Clec16a
entrez
74374
canonical
uniprot
Q80U30
canonical
ensembl
ENSMUSG00000068663
resolver
ensp
ENSMUSP00000065423
resolver
ensp
ENSMUSP00000111494
resolver
ensp
ENSMUSP00000123189
resolver
ensp
ENSMUSP00000274371
resolver
ensp
ENSMUSP00000330195
resolver
genesymbol
Clec16a
resolver
genesymbol_syn
Kiaa0350
resolver
uniprot
A6X932
resolver
uniprot
B2RSL3
resolver
uniprot
Q3TCF2
resolver
uniprot
Q3U0F5
resolver
uniprot
Q3U2F6
resolver
uniprot
Q8CEQ8
resolver
uniprot_entry
CL16A_MOUSE
resolver
uniprot_sec
A6X932
resolver
uniprot_sec
B2RSL3
resolver
uniprot_sec
Q3TCF2
resolver
uniprot_sec
Q3U0F5
resolver
uniprot_sec
Q3U2F6
resolver
uniprot_sec
Q8CEQ8
resolver
amino_acid_sequence
MFGRSRSWVGGGHSKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVSLDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENPDKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYTKPAQDVPRSSAKPSIRCFIKPTETLERSLEMNKHKGKKRMQKRPNYKNVGEEEDEERGSAEDAQEDAEKTKEIEMVIMKLGKLSEVAAAGTSVQEQNTTDEEKSAATNSENAQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLKRIQLPVPSEAEKTTYNHLLAERLIRIMNNAAQPDGRIRLATLELSCLLLKQQVLTSSGCVIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMVQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLCSSSSSSQHLPFRFYEQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSPSPPFASGSPGGSGSTSHCDSGGSSSAPSATQSPADAPTTPEQPQPHLDQSVIGNEMDVNSKPSKNSSARSSEGETMHLSPSLLPAQQPTISLLYEDTADTLSVESLTIVPPVDPHSLRALSGISQLPTLPAADTETPAEGAVNPEPAEPTEH
uniprot
proteins
function
FUNCTION: Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteasomal degradation, RNF41/NRDP1 which regulates proteasomal degradation of PRKN. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health. {ECO:0000269|PubMed:24949970}.
uniprot
proteins
mass_dalton
116232
uniprot
proteins
protein_family
CLEC16A/gop-1 family
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19855005
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24949970
uniprot
proteins
sequence_length
1036
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:24949970}; Peripheral membrane protein {ECO:0000269|PubMed:24949970}. Lysosome membrane {ECO:0000269|PubMed:24949970}; Peripheral membrane protein {ECO:0000269|PubMed:24949970}. Note=Associates with the endolysosome membrane. {ECO:0000269|PubMed:24949970}.
uniprot
proteins