P24268
uniprot
P24268
canonical
amino_acid_sequence
MQTPGVLLLILGLLDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL
uniprot
proteins
ec_number
3.4.23.5
uniprot
proteins
function
FUNCTION: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. {ECO:0000250|UniProtKB:P07339}.
uniprot
proteins
mass_dalton
44681
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:P07339}.; PTM: Undergoes proteolytic cleavage and activation by ADAM30. {ECO:0000250|UniProtKB:P07339}.
uniprot
proteins
protein_family
Peptidase A1 family
uniprot
proteins
pubmed
1883350
uniprot
proteins
pubmed
2243802
uniprot
proteins
pubmed
24090084
uniprot
proteins
pubmed
3182800
uniprot
proteins
sequence_length
407
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome. Melanosome {ECO:0000250}. Secreted, extracellular space {ECO:0000250}.
uniprot
proteins