Dis3l
entrez
213550
canonical
uniprot
Q8C0S1
canonical
ensembl
ENSMUSG00000032396
resolver
ensp
ENSMUSP00000109522
resolver
ensp
ENSMUSP00000113503
resolver
ensp
ENSMUSP00000129772
resolver
genesymbol
Dis3l
resolver
genesymbol_syn
Kiaa1955
resolver
uniprot
Q69Z56
resolver
uniprot_entry
DI3L1_MOUSE
resolver
uniprot_sec
Q69Z56
resolver
amino_acid_sequence
MLQKREKVLLLRTFQGRTLRIVREHYLRPSVPCNSPLCPQPAACRNDGKLLAAEVTHYVIPDWKVVQDYLEVLEFPELKGVIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCVLFANEFQQHCYLPREKGEAMEKWQTRSIYNSAVWYYHHCEDRMPIVMVTEDEEAIQKYGSETEGVFVISFKNYLDNFWPDLKAAHDLCDSILQSRRERETESQETHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLHGASSKDSGLVSDILIHGSKARNRSIHGDVVVVEMLPKSEWKGRTAALGENDSDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAEALQDFRVVVRIDSWEATSVYPNGHFVRVLGRIGDLEGEIATILVENSISVVPFSEAQMCEMPVNTPENPWKVSPKEEQERKDLRTTHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDKQSQQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPKDPLVNKLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETEERCIADGVIYSIRTNGVLVFIPRFGIKGAAYLKNKDSLVISCGPEGSSEWKPGSLQRSQNKIISTTAGGQSVTFHLFDHVTVRISVQASRCHSDTIRLEIVSNKPYMIPNTELCHQSSLLKSELVKEVTRSVEEAQLAQEVKGKVIQEEHQEYCQTKGRSLYTLLEEIRDLALLDVSDSCAM
uniprot
proteins
ec_number
3.1.13.1
uniprot
proteins
function
FUNCTION: Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. {ECO:0000250|UniProtKB:Q8TF46}.
uniprot
proteins
mass_dalton
120284
uniprot
proteins
protein_family
RNR ribonuclease family
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1053
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8TF46}.
uniprot
proteins