Aldh3a1
entrez
25375
canonical
uniprot
P11883
canonical
ensembl
ENSRNOG00000002331
resolver
ensp
ENSRNOP00000003182
resolver
genesymbol
Aldh3a1
resolver
genesymbol_syn
Aldd
resolver
genesymbol_syn
Aldh3
resolver
uniprot_entry
AL3A1_RAT
resolver
amino_acid_sequence
MSSISDTVKRAREAFNSGKTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSYYEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQYMDQNLYLVVKGGVPETTELLKERFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDNQKVAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLEEAIQFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVKSLLNEEAHKARYPPSPAKMPRH
uniprot
proteins
ec_number
1.2.1.5
uniprot
proteins
function
FUNCTION: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:2831537). Preferentially oxidizes aromatic aldehyde substrates (PubMed:2831537). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). {ECO:0000250|UniProtKB:P47739, ECO:0000269|PubMed:2831537, ECO:0000305}.
uniprot
proteins
mass_dalton
50339
uniprot
proteins
protein_family
Aldehyde dehydrogenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2091023
uniprot
proteins
pubmed
2713359
uniprot
proteins
pubmed
2831537
uniprot
proteins
pubmed
8509394
uniprot
proteins
pubmed
9095201
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P47739}.
uniprot
proteins