Tnfrsf1a
entrez
25625
canonical
uniprot
P22934
canonical
ensembl
ENSRNOG00000031312
resolver
ensp
ENSRNOP00000042371
resolver
enst
ENSRNOT00000048529
resolver
genesymbol
Tnfrsf1a
resolver
genesymbol_syn
Tnfr-1
resolver
genesymbol_syn
Tnfr1
resolver
uniprot
A0A0G2JSU9
resolver
uniprot
Q5U1X6
resolver
uniprot
Q91V30
resolver
uniprot
Q91Y93
resolver
uniprot_entry
A0A0G2JSU9_RAT
resolver
uniprot_entry
TNR1A_RAT
resolver
uniprot_sec
Q5U1X6
resolver
uniprot_sec
Q91V30
resolver
uniprot_sec
Q91Y93
resolver
amino_acid_sequence
MGLPIVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDNLCPQGKYAHPKNNSICCTKCHKGTYLVSDCPSPGQETVCEVCDKGTFTASQNHVRQCLSCKTCRKEMFQVEISPCKADMDTVCGCKKNQFQRYLSETHFQCVDCSPCFNGTVTIPCKEKQNTVCNCHAGFFLSGNECTPCSHCKKNQECMKLCLPPVANVTNPQDSGTAVLLPLVIFLGLCLLFFICISLLCRYPQWRPRVYSIICRDSAPVKEVEGEGIVTKPLTPASIPAFSPNPGFNPTLGFSTTPRFSHPVSSTPISPVFGPSNWHNFVPPVREVVPTQGADPLLYGSLNPVPIPAPVRKWEDVVAAQPQRLDTADPAMLYAVVDGVPPTRWKEFMRLLGLSEHEIERLELQNGRCLREAHYSMLEAWRRRTPRHEATLDVVGRVLCDMNLRGCLENIRETLESPAHSSTTHLPR
uniprot
proteins
function
FUNCTION: Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
50969
uniprot
proteins
pubmed
11486281
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1702293
uniprot
proteins
sequence_length
461
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 212..234; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins