Cnr2
entrez
57302
canonical
uniprot
Q9QZN9
canonical
ensembl
ENSRNOG00000009260
resolver
ensp
ENSRNOP00000012342
resolver
ensp
ENSRNOP00000066697
resolver
genesymbol
Cnr2
resolver
uniprot
C6G964
resolver
uniprot
C6G965
resolver
uniprot
Q9EP74
resolver
uniprot_entry
C6G964_RAT
resolver
uniprot_entry
CNR2_RAT
resolver
uniprot_sec
C6G965
resolver
uniprot_sec
Q9EP74
resolver
amino_acid_sequence
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
uniprot
proteins
function
FUNCTION: Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
39359
uniprot
proteins
post_translational_modification
PTM: Constitutively phosphorylated on Ser-352; phosphorylation increases cell internalization and desensitizes the receptor. {ECO:0000250}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10688601
uniprot
proteins
pubmed
12084572
uniprot
proteins
pubmed
12153574
uniprot
proteins
pubmed
16224028
uniprot
proteins
pubmed
18286196
uniprot
proteins
sequence_length
360
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:18286196}; Multi-pass membrane protein {ECO:0000269|PubMed:18286196}. Cell projection, dendrite {ECO:0000269|PubMed:18286196}. Perikaryon {ECO:0000269|PubMed:18286196}. Note=Localizes to apical dendrite of pyramidal neurons.
uniprot
proteins
transmembrane_region
TRANSMEM 34..59; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 72..92; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 105..129; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 150..172; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 189..214; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 247..267; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 280..301; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins