ODF2
entrez
4957
canonical
uniprot
Q5BJF6
canonical
ensembl
ENSG00000136811
resolver
ensp
ENSP00000342581
resolver
ensp
ENSP00000361877
resolver
ensp
ENSP00000361893
resolver
ensp
ENSP00000361901
resolver
ensp
ENSP00000377161
resolver
ensp
ENSP00000377166
resolver
ensp
ENSP00000396687
resolver
ensp
ENSP00000403453
resolver
ensp
ENSP00000437579
resolver
ensp
ENSP00000473949
resolver
enst
ENST00000351030
resolver
enst
ENST00000393527
resolver
genesymbol
ODF2
resolver
hgnc
HGNC:8114
resolver
uniprot
A0A024R8A5
resolver
uniprot
A0A8J8YVX4
resolver
uniprot
A0A8J8Z1C3
resolver
uniprot
B1AND3
resolver
uniprot
B3KSD5
resolver
uniprot
B4DRK4
resolver
uniprot
B4DUU0
resolver
uniprot
B4DX03
resolver
uniprot
B4DX73
resolver
uniprot
B4DX85
resolver
uniprot
B4DZ02
resolver
uniprot
E7EWL2
resolver
uniprot
F5H6J4
resolver
uniprot
O14721
resolver
uniprot
O60631
resolver
uniprot
Q1W2J6
resolver
uniprot
Q6UN26
resolver
uniprot
Q7Z5I6
resolver
uniprot
Q96FN2
resolver
uniprot_entry
A0A024R8A5_HUMAN
resolver
uniprot_entry
A0A8J8YVX4_HUMAN
resolver
uniprot_entry
A0A8J8Z1C3_HUMAN
resolver
uniprot_entry
B3KSD5_HUMAN
resolver
uniprot_entry
B4DUU0_HUMAN
resolver
uniprot_entry
B4DX03_HUMAN
resolver
uniprot_entry
B4DX85_HUMAN
resolver
uniprot_entry
ODFP2_HUMAN
resolver
uniprot_sec
B1AND3
resolver
uniprot_sec
B4DRK4
resolver
uniprot_sec
B4DX73
resolver
uniprot_sec
B4DZ02
resolver
uniprot_sec
E7EWL2
resolver
uniprot_sec
F5H6J4
resolver
uniprot_sec
O14721
resolver
uniprot_sec
O60631
resolver
uniprot_sec
Q1W2J6
resolver
uniprot_sec
Q6UN26
resolver
uniprot_sec
Q7Z5I6
resolver
uniprot_sec
Q96FN2
resolver
amino_acid_sequence
MSASSSGGSPRFPSCGKNGVTSLTQKKVLRAPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARPVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERMKEEKDFTILQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYSTFLTSSPIRSRSPPA
uniprot
proteins
function
FUNCTION: Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly. {ECO:0000269|PubMed:16966375}.
uniprot
proteins
mass_dalton
95401
uniprot
proteins
post_translational_modification
PTM: Tyrosine phosphorylated. Phosphorylated by TSSK4 on Ser-95. {ECO:0000250|UniProtKB:A3KGV1, ECO:0000250|UniProtKB:Q2MJU7}.
uniprot
proteins
protein_family
ODF2 family
uniprot
proteins
pubmed
10381817
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16966375
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23400999
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
30683861
uniprot
proteins
sequence_length
829
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:16966375}. Cell projection, cilium {ECO:0000250|UniProtKB:A3KGV1}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23400999}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:A3KGV1}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A3KGV1}. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles. {ECO:0000250|UniProtKB:A3KGV1}.
uniprot
proteins