EEF1AKMT4-ECE2
entrez
110599583
canonical
uniprot
P0DPD8
canonical
ensembl
ENSG00000284917
resolver
ensp
ENSP00000384223
resolver
enst
ENST00000402825
resolver
genesymbol
EEF1AKMT4-ECE2
resolver
hgnc
HGNC:53615
resolver
uniprot
A5PLK8
resolver
uniprot
O60344
resolver
uniprot
Q6NTG7
resolver
uniprot
Q6UW36
resolver
uniprot
Q8NFD7
resolver
uniprot
Q96NX3
resolver
uniprot
Q96NX4
resolver
uniprot
Q9BRZ8
resolver
uniprot_entry
EFCE2_HUMAN
resolver
uniprot_sec
A5PLK8
resolver
uniprot_sec
O60344
resolver
uniprot_sec
Q6NTG7
resolver
uniprot_sec
Q6UW36
resolver
uniprot_sec
Q8NFD7
resolver
uniprot_sec
Q96NX3
resolver
uniprot_sec
Q96NX4
resolver
uniprot_sec
Q9BRZ8
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by phosphoramidon. {ECO:0000250|UniProtKB:P0DPE2}.
uniprot
proteins
amino_acid_sequence
MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
ec_number
3.4.24.71
uniprot
proteins
function
FUNCTION: Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity (By similarity). May play a role in amyloid-beta processing (By similarity). {ECO:0000250|UniProtKB:P0DPD9, ECO:0000250|UniProtKB:P0DPE2}.
uniprot
proteins
mass_dalton
99773
uniprot
proteins
protein_family
Methyltransferase superfamily; Peptidase M13 family
uniprot
proteins
pubmed
11718899
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
16641997
uniprot
proteins
sequence_length
883
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:P0DPE2}; Single-pass membrane protein {ECO:0000250|UniProtKB:P0DPE2}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:P0DPE2}.
uniprot
proteins
transmembrane_region
TRANSMEM 179..199; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins