Adcy4
entrez
104110
canonical
uniprot
Q91WF3
canonical
ensembl
ENSMUSG00000022220
resolver
ensp
ENSMUSP00000002398
resolver
ensp
ENSMUSP00000130530
resolver
ensp
ENSMUSP00000289683
resolver
enst
ENSMUST00000002398
resolver
enst
ENSMUST00000170223
resolver
genesymbol
Adcy4
resolver
uniprot_entry
ADCY4_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Activated by forskolin. Insensitive to calcium/calmodulin. Stimulated by GNAS and by the G protein beta and gamma subunit complex. {ECO:0000250|UniProtKB:P26770}.
uniprot
proteins
amino_acid_sequence
MARLFSPRPPPSEDLFYETYYSLSQQYPLLILLLVIVLCALVALPAVAWASGRELTSDPSFLTTVLCALGGFSLLLGLASREQQLQRWTRPLSGLIWVALLALGYGFLFTGGVVSAWDQVSFFLFIIFTVYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWQPESQRALLPQLAANAVLFLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQRSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRVATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGAYAVERADTEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAKGLLSSLEGHTMRPSLLMTRYLESWGAAKPFAHLSHLDSPVSTSTPLPEKAFSPQWSLDRSRTPRGLDDELDTGDAKFFQVIEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQMLVTTRPPALIITYSITFLLFFLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGFRVALGTATILLVFTMAIASLLFLPVSSDCLFLASNVSSVTFNASWEMPGSLPLISIPLISIPYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYQSPSDSRPGVLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDSERSCSHLGTMVEFAVALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETARALQSLGYTCYSRGSIKVKGKGELCTYFLNTDLTRTGSPSAS
uniprot
proteins
ec_number
4.6.1.1
uniprot
proteins
function
FUNCTION: Catalyzes the formation of the signaling molecule cAMP in response to G protein signaling. {ECO:0000250|UniProtKB:P26770}.
uniprot
proteins
mass_dalton
120380
uniprot
proteins
protein_family
Adenylyl cyclase class-4/guanylyl cyclase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
1077
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P26770}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P26770}. Cytoplasm {ECO:0000250|UniProtKB:Q8NFM4}.
uniprot
proteins
transmembrane_region
TRANSMEM 29..50; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 61..80; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 94..117; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 120..138; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 141..162; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 170..190; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 583..604; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 608..630; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 661..684; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 718..738; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 746..766; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 793..809; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins