Tmeff2
entrez
56363
canonical
uniprot
Q9QYM9
canonical
ensembl
ENSMUSG00000026109
resolver
ensp
ENSMUSP00000080533
resolver
ensp
ENSMUSP00000182696
resolver
genesymbol
Tmeff2
resolver
uniprot
Q3UY20
resolver
uniprot
Q8CDH1
resolver
uniprot
Q9JJE3
resolver
uniprot_entry
TEFF2_MOUSE
resolver
uniprot_sec
Q3UY20
resolver
uniprot_sec
Q8CDH1
resolver
uniprot_sec
Q9JJE3
resolver
amino_acid_sequence
MVLWESPRQCSSWTLCEGFCWLLLLPVTLLIIARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDTGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI
uniprot
proteins
function
FUNCTION: May be a survival factor for hippocampal and mesencephalic neurons. The shedded form may up-regulate cell proliferation (By similarity). {ECO:0000250|UniProtKB:Q9UIK5}.
uniprot
proteins
mass_dalton
41415
uniprot
proteins
post_translational_modification
PTM: O-glycosylated; contains chondroitin sulfate glycosaminoglycans. {ECO:0000250|UniProtKB:Q9UIK5}.; PTM: A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or pro-inflammatory cytokines such as TNFalpha, and is mediated by a metalloproteinase ADAM (By similarity). {ECO:0000250|UniProtKB:Q9UIK5}.
uniprot
proteins
protein_family
Tomoregulin family
uniprot
proteins
pubmed
10600548
uniprot
proteins
pubmed
10903839
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
374
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 321..341; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins