Psmb8
entrez
24968
canonical
uniprot
P28064
canonical
ensembl
ENSRNOG00000000456
resolver
ensp
ENSRNOP00000000528
resolver
enst
ENSRNOT00000000528
resolver
genesymbol
Psmb8
resolver
uniprot
A0A023IKD2
resolver
uniprot
A0A023IMI6
resolver
uniprot
Q6MGA4
resolver
uniprot_entry
A0A023IMI6_RAT
resolver
uniprot_entry
PSB8_RAT
resolver
uniprot_sec
A0A023IKD2
resolver
uniprot_sec
Q6MGA4
resolver
amino_acid_sequence
MALLDLCGAPRGQRPEWAAVDAGSGLRSDPGHYSFSVQAPELALPRGMQPTEFLRSFGDDQERKVQIEMAHGTTTLAFKFQHGVIVAVDSRASAGSYIATIRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKKGPGLYYVDDNGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLARRAIVYATHRDSYSGGVVNMYHMKKDGWVKVESTDVSDLLHKYREATL
uniprot
proteins
ec_number
3.4.25.1
uniprot
proteins
function
FUNCTION: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. May participate in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity). Required for adipocyte differentiation (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:P28062}.
uniprot
proteins
mass_dalton
30570
uniprot
proteins
post_translational_modification
PTM: Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity. {ECO:0000250|UniProtKB:O35955}.
uniprot
proteins
protein_family
Peptidase T1B family
uniprot
proteins
pubmed
1451788
uniprot
proteins
pubmed
15060004
uniprot
proteins
pubmed
16988215
uniprot
proteins
sequence_length
276
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
uniprot
proteins