RXFP4
entrez
339403
canonical
uniprot
Q8TDU9
canonical
ensembl
ENSG00000173080
resolver
ensp
ENSP00000357301
resolver
enst
ENST00000368318
resolver
genesymbol
RXFP4
resolver
genesymbol_syn
GPCR142
resolver
genesymbol_syn
GPR100
resolver
genesymbol_syn
RLN3R2
resolver
hgnc
HGNC:14666
resolver
uniprot
B0M0L4
resolver
uniprot
Q3MJB1
resolver
uniprot
Q8NGZ8
resolver
uniprot_entry
RL3R2_HUMAN
resolver
uniprot_sec
B0M0L4
resolver
uniprot_sec
Q3MJB1
resolver
uniprot_sec
Q8NGZ8
resolver
amino_acid_sequence
MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFGVEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
uniprot
proteins
function
FUNCTION: High affinity receptor for INSL5. Also acts as a receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. {ECO:0000269|PubMed:14522967, ECO:0000269|PubMed:15525639}.
uniprot
proteins
mass_dalton
41141
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12044878
uniprot
proteins
pubmed
14522967
uniprot
proteins
pubmed
14530218
uniprot
proteins
pubmed
14623098
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15525639
uniprot
proteins
pubmed
16710414
uniprot
proteins
sequence_length
374
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 44..64; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 79..99; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 155..175; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 210..230; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 250..270; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 282..302; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins