TAS2R8
entrez
50836
canonical
uniprot
Q9NYW2
canonical
ensembl
ENSG00000121314
resolver
ensembl
ENSG00000272712
resolver
ensembl
ENSG00000277316
resolver
ensp
ENSP00000240615
resolver
ensp
ENSP00000461158
resolver
ensp
ENSP00000484163
resolver
enst
ENST00000240615
resolver
enst
ENST00000572823
resolver
enst
ENST00000610444
resolver
genesymbol
TAS2R8
resolver
hgnc
HGNC:14915
resolver
uniprot
Q4KN29
resolver
uniprot
Q645Y2
resolver
uniprot_entry
TA2R8_HUMAN
resolver
uniprot_sec
Q4KN29
resolver
uniprot_sec
Q645Y2
resolver
amino_acid_sequence
MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYILTNLVIARICLISVMVVNGIVIVLNPDVYTKNKQQIVIFTFWTFANYLNMWITTCLNVFYFLKIASSSHPLFLWLKWKIDMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHAIAKHKRNITEMFHVSKIPYFEPLTLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMTSFIFFFFLYYISSILMTFSYLMTKYKLAVEFGEIAAILYPLGHSLILIVLNNKLRQTFVRMLTCRKIACMI
uniprot
proteins
function
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
uniprot
proteins
mass_dalton
35877
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
10761934
uniprot
proteins
pubmed
10761935
uniprot
proteins
pubmed
11696554
uniprot
proteins
pubmed
12139982
uniprot
proteins
pubmed
12581520
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15496549
uniprot
proteins
sequence_length
309
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 51..71; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 83..103; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 132..152; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 185..205; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 240..260; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 267..287; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins