Ift122
entrez
81896
canonical
uniprot
Q6NWV3
canonical
ensembl
ENSMUSG00000030323
resolver
ensp
ENSMUSP00000045468
resolver
ensp
ENSMUSP00000108545
resolver
ensp
ENSMUSP00000108547
resolver
ensp
ENSMUSP00000322598
resolver
enst
ENSMUST00000112923
resolver
genesymbol
Ift122
resolver
genesymbol_syn
Wdr10
resolver
uniprot
E9Q9G8
resolver
uniprot
Q6KAU2
resolver
uniprot
Q8C8U5
resolver
uniprot
Q8CD77
resolver
uniprot_entry
E9Q9G8_MOUSE
resolver
uniprot_entry
IF122_MOUSE
resolver
uniprot_sec
Q6KAU2
resolver
uniprot_sec
Q8C8U5
resolver
uniprot_sec
Q8CD77
resolver
amino_acid_sequence
MRAVLTWRDKAEQCIYDLAFKPDGTQLILAAGNRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSIIIWTSKLEGILKYTHNDSIQCVSYNPVTHQLASCSSSDFGLWSPEQKSVSKHKSSSKITCCSWTNDGQYLALGMANGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSREEHNDILAVADWGQKLSFYQLSGKQIGKDRPLNFDPCCISYFTKGEYILVGGSDKQVSLFTKDGVRLGTVGEQNSWVWTCRVKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIKCRELVKKIAIYKNRLAIQLPEKILIYELYSEDSTDMHYRVKEKIVKKFECNLLVVCADHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPAGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRNKLAVVDENDTCLVYDIHTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHQQKLQGFVVGYNGSKIFCLHVFSMSAVEVPQSAPMYQYLDRKMFKEAYQIACLGVTDADWRELAMEALEGLEFETARKAFTRVQDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALDMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNINEPKAAVEMYISAGEHAKAIEISGSHGWVDMLIDIARKLDKAEREPLLMCACYFKKLDSPGYAAETYLKIGDLKSLVQLYVDTKRWDEAFALGEKHPEFKDDVYVPYAQWLAENDRFEEAQKAFHKAGRQGEAVRVLEQLTHNAVVESRFNDAAYYYWMLSMQCLDMAQDPAQKDAMLDKFHHFQHLAELYHGYQTIHRYTEEPFSFDLPETLFNISKFLLHSLTKATPLGISKVNTLFTLAKQSKALGAYKLARHAYDKLRGLQIPARIQKSIELGTLTIRSKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYEVLHLVEFYLEEGITDEEAVALIDLEAPRHKREGKWRETSSNNSQTLKLDETMDSIGEDDPFTAKLSFEQGSSEFVPVVVNRSVLRSMSRRDVLIKRWPPPLQWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQHACCPYCRRRIDDTGP
uniprot
proteins
function
FUNCTION: As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking (By similarity). Involved in cilia formation during neuronal patterning (PubMed:19000668, PubMed:21209331). Acts as a negative regulator of Shh signaling (PubMed:19000668, PubMed:21209331). {ECO:0000250|UniProtKB:Q9HBG6, ECO:0000269|PubMed:19000668, ECO:0000269|PubMed:21209331}.
uniprot
proteins
mass_dalton
134798
uniprot
proteins
pubmed
15449545
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19000668
uniprot
proteins
pubmed
19208653
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21209331
uniprot
proteins
sequence_length
1182
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000269|PubMed:21209331}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:21209331}. Note=Localizes to photoreceptor connecting cilia. {ECO:0000269|PubMed:21209331}.
uniprot
proteins