IPPK
entrez
64768
canonical
uniprot
Q9H8X2
canonical
ensembl
ENSG00000127080
resolver
ensp
ENSP00000287996
resolver
ensp
ENSP00000364672
resolver
ensp
ENSP00000656844
resolver
ensp
ENSP00000783945
resolver
enst
ENST00000287996
resolver
enst
ENST00000375522
resolver
genesymbol
IPPK
resolver
genesymbol_syn
C9orf12
resolver
hgnc
HGNC:14645
resolver
uniprot
Q5T9F7
resolver
uniprot
Q9H7V8
resolver
uniprot
X6R9A6
resolver
uniprot_entry
IPPK_HUMAN
resolver
uniprot_entry
X6R9A6_HUMAN
resolver
uniprot_sec
Q5T9F7
resolver
uniprot_sec
Q9H7V8
resolver
amino_acid_sequence
MEEGKMDENEWGYHGEGNKSLVVAHAQRCVVLRFLKFPPNRKKTSEEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLCLKIQSERPESRCDKDLDTLSGYAMCLPNLTRLQTYRFAEHRPILCVEIKPKCGFIPFSSDVTHEMKHKVCRYCMHQHLKVATGKWKQISKYCPLDLYSGNKQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVADWSELAHHLKPFFFPSNGLASGPHCTRAVIRELVHVITRVLLSGSDKGRAGTLSPGLGPQGPRVCEASPFSRSLRCQGKNTPERSGLPKGCLLYKTLQVQMLDLLDIEGLYPLYNRVERYLEEFPEERKTLQIDGPYDEAFYQKLLDLSTEDDGTVAFALTKVQQYRVAMTAKDCSIMIALSPCLQDASSDQRPVVPSSRSRFAFSVSVLDLDLKPYESIPHQYKLDGKIVNYYSKTVRAKDNAVMSTRFKESEDCTLVLHKV
uniprot
proteins
ec_number
2.7.1.158
uniprot
proteins
function
FUNCTION: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-induced apoptosis. {ECO:0000269|PubMed:12084730, ECO:0000269|PubMed:15967797}.
uniprot
proteins
mass_dalton
56017
uniprot
proteins
protein_family
IPK1 type 2 family
uniprot
proteins
pubmed
12084730
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15967797
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
491
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins