Nuf2
entrez
304951
canonical
uniprot
Q6AYL9
canonical
ensembl
ENSRNOG00000002711
resolver
ensembl
ENSRNOG00055023056
resolver
ensembl
ENSRNOG00060020699
resolver
ensembl
ENSRNOG00065020828
resolver
ensp
ENSRNOP00000003650
resolver
ensp
ENSRNOP00055032170
resolver
ensp
ENSRNOP00060029532
resolver
ensp
ENSRNOP00065028475
resolver
enst
ENSRNOT00000003650
resolver
enst
ENSRNOT00055039624
resolver
enst
ENSRNOT00060035887
resolver
enst
ENSRNOT00065035365
resolver
genesymbol
Nuf2
resolver
genesymbol_syn
Cdca1
resolver
uniprot_entry
NUF2_RAT
resolver
amino_acid_sequence
METLSFPRYNIAEIVVHIRNKLLTGADGKNLSKSDFLPNPKPEVLYMIYMRALQLVYGVRLEHFYMMPVNIEVMYPHIMEGFLPVSNLFFHLDSFMPICRVNDFEIADILYPKANRTSRFLSGIINFIHFRETCLEKYEEFLLQNKSSVDKIQQLSNAHQEALMKLEKLNSVPVEEQEEFKQLKDDIQELQHLLNQDFRQKTTLLQERYTKMKSDFSEKTKHVNELKLSVVSLKEVQDSLKSKIVDSPEKLKNYKEKMKDTVQKLRSAREEVMEKYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSILKESLNLEGQIDSDSSELKKLKTEENSLIRLMTLKKERLATMQFKINKKQEDVKQYKRTMIEDCNKVQEKRDAVCEQVTAINQDIHKIKSGIQQLRDAEKREKLKSQEILVDLKSALEKYHEGIEKTTEECCTRIGGKTAELKRRMFKMPP
uniprot
proteins
function
FUNCTION: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. {ECO:0000250|UniProtKB:Q9BZD4}.
uniprot
proteins
mass_dalton
54556
uniprot
proteins
post_translational_modification
PTM: Can be phosphorylated by AURKA and AURKB. {ECO:0000250}.
uniprot
proteins
protein_family
NUF2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
464
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore (By similarity). {ECO:0000250}.
uniprot
proteins