RAPGEF5
entrez
9771
canonical
uniprot
Q92565
canonical
ensembl
ENSG00000136237
resolver
ensp
ENSP00000343656
resolver
ensp
ENSP00000384044
resolver
ensp
ENSP00000499535
resolver
enst
ENST00000344041
resolver
genesymbol
RAPGEF5
resolver
genesymbol_syn
GFR
resolver
genesymbol_syn
KIAA0277
resolver
genesymbol_syn
MRGEF
resolver
hgnc
HGNC:16862
resolver
uniprot
A0A0S2Z561
resolver
uniprot
A4D140
resolver
uniprot
A8MQ07
resolver
uniprot
Q8IXU5
resolver
uniprot_entry
A0A0S2Z561_HUMAN
resolver
uniprot_entry
A8MQ07_HUMAN
resolver
uniprot_entry
RPGF5_HUMAN
resolver
uniprot_sec
A4D140
resolver
uniprot_sec
Q8IXU5
resolver
amino_acid_sequence
MGSSRLRVFDPHLERKDSAAALSDRELPLPTFDVPYFKYIDEEDEDDEWSSRSQSSTEDDSVDSLLSDRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPRRKRKVLHLVSQWIALYKDWLPEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVTETEEIFCHVYITEHSYVSVKAKVSSIAQEILKVVAEKIQYAEEDLALVAITFSGEKHELQPNDLVISKSLEASGRIYVYRKDLADTLNPFAENEESQQRSMRILGMNTWDLALELMNFDWSLFNSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGDLSPKEHQELKSYVNHLYVIDSQQALFELSHRIEPRV
uniprot
proteins
function
FUNCTION: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation. {ECO:0000269|PubMed:10777494, ECO:0000269|PubMed:10934204}.
uniprot
proteins
mass_dalton
67733
uniprot
proteins
pubmed
10486569
uniprot
proteins
pubmed
10777494
uniprot
proteins
pubmed
10934204
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9039502
uniprot
proteins
sequence_length
580
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins