TMEM174
entrez
134288
canonical
uniprot
Q8WUU8
canonical
ensembl
ENSG00000164325
resolver
ensp
ENSP00000296776
resolver
genesymbol
TMEM174
resolver
hgnc
HGNC:28187
resolver
uniprot
B2RDA0
resolver
uniprot
Q96N81
resolver
uniprot_entry
TM174_HUMAN
resolver
uniprot_sec
B2RDA0
resolver
uniprot_sec
Q96N81
resolver
amino_acid_sequence
MEQGSGRLEDFPVNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPVLLSVGVTFILIAVCKFKMLSCQLCKESEERVPDSEQTPGGPSFVFTGINQPITFHGATVVQYIPPPYGSPEPMGINTSYLQSVVSPCGLITSGGAAAAMSSPPQYYTIYPQDNSAFVVDEGCLSFTDGGNHRPNPDVDQLEETQLEEEACACFSPPPYEEIYSLPR
uniprot
proteins
function
FUNCTION: Regulator of plasma phosphate homeostasis. Decreases serum inorganic phosphate (Pi) uptake by regulating the sodium-phosphate cotransporter SLC34A1 trafficking by PTH and FGF23 in the kidney. {ECO:0000250|UniProtKB:Q9DCX7}.
uniprot
proteins
mass_dalton
26287
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20331980
uniprot
proteins
pubmed
35459732
uniprot
proteins
sequence_length
243
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20331980}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:35459732}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins