Drc5
entrez
21645
canonical
uniprot
A6H639
canonical
ensembl
ENSMUSG00000023949
resolver
ensp
ENSMUSP00000109175
resolver
ensp
ENSMUSP00000156920
resolver
enst
ENSMUST00000113547
resolver
enst
ENSMUST00000233588
resolver
genesymbol
Drc5
resolver
genesymbol_syn
D17sil1
resolver
genesymbol_syn
Tcte1
resolver
uniprot
Q62294
resolver
uniprot_entry
DRC5_MOUSE
resolver
uniprot_sec
Q62294
resolver
amino_acid_sequence
MQETPSVPSNSSSHSQSVLTIQRQVSALGSSSTGPTSLKTSSTPTPGQLKTKVPNVRRMRRIISEDAEWSLAIVPLLTELCIQHIVKNFQNNPILKQLPLEHQKKVLSNLPPELPLTVTANLIDDENYWHRCCIKRWSVCHVSRHGGSWKRMFFERHLENLLKLFIPGTTDPNVILDLLPLCRNYVRRIHVDQFLPPVRMPTPLQGEEQSDSGSEGEGSEPEKDHYQLQTLVGGLKHLEELDLVYGVKDCGMNFEWNLFLFTYRDCYSLAATIKACHTLKIFKLTRSKVDDDKARILIRSLLDHPALEELDLSHNLIGDRGARAAAKLLSHSRLRVLNLANNQLQAPGAQSLAHALAHNTNLVFLNLRLNCIEDEGGQAIAHALETNKCLSVLHLGGNKLSEPTATLLSQMLTVNTTLVSLNLSCNHIGQDGGKQLLEGISDNKTILEFDLRLSDVSQESEYLIGQVLHANREAARQRTLNPGHFSSPTNNCTENSVV
uniprot
proteins
function
FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC (By similarity). Required for sperm motility (PubMed:28630322). {ECO:0000250|UniProtKB:A8HMZ4, ECO:0000269|PubMed:28630322}.
uniprot
proteins
mass_dalton
55518
uniprot
proteins
protein_family
DRC5 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2568335
uniprot
proteins
pubmed
28630322
uniprot
proteins
pubmed
31961863
uniprot
proteins
sequence_length
498
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000269|Ref.2}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A8HMZ4}. Note=Detected along the length of the sperm flagellum. {ECO:0000269|Ref.2}.
uniprot
proteins