Necab3
entrez
56846
canonical
uniprot
Q9D6J4
canonical
ensembl
ENSMUSG00000027489
resolver
ensp
ENSMUSP00000000895
resolver
ensp
ENSMUSP00000105338
resolver
ensp
ENSMUSP00000256373
resolver
genesymbol
Necab3
resolver
genesymbol_syn
Apba2bp
resolver
genesymbol_syn
Xb51
resolver
uniprot
A1L0S0
resolver
uniprot
A1L0S1
resolver
uniprot
A2AKE8
resolver
uniprot
A2AKE9
resolver
uniprot
Q3TYZ9
resolver
uniprot
Q9ESR0
resolver
uniprot_entry
NECA3_MOUSE
resolver
uniprot_sec
A1L0S0
resolver
uniprot_sec
A1L0S1
resolver
uniprot_sec
A2AKE8
resolver
uniprot_sec
A2AKE9
resolver
uniprot_sec
Q3TYZ9
resolver
uniprot_sec
Q9ESR0
resolver
amino_acid_sequence
MACAGLLTVCLLGPPAPQQPRHSAPAAGHALFQDVFRRADKNDDGKLSFEEFQNYFADGVLSSAELRELFSGIDDHLTDNLETEKLCDYFSTHLGVYRPVLAALESLNRAVLTAMDTTKLEYEQASKVDQFVTRFLLRETVNQLQALQTSLEGASDTLEAQAHGQRLDEETIKAQSRPCGSRRAGRRALRSISWSPSWSPGSSDTGRSSEAEQQWRLQVNRLQELIDQLECKAPRLEPTHEEDLTKGFDSHILVAQRQVQVAEDALQDFHRALCCYMNFTGAQSHCLHVSAQKMLDNAAFTLYEFWQDEASWRRHQQSPCSKAFQRTLIDHLQAPDTLTTVFFPASWWIMNNN
uniprot
proteins
function
FUNCTION: Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta (By similarity). May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3 (By similarity). {ECO:0000250|UniProtKB:Q96P71}.
uniprot
proteins
mass_dalton
39906
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by NEK2. {ECO:0000250|UniProtKB:Q96P71}.
uniprot
proteins
pubmed
10833507
uniprot
proteins
pubmed
14697346
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
353
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q96P71}.
uniprot
proteins