CA14
entrez
23632
canonical
uniprot
Q9ULX7
canonical
ensembl
ENSG00000118298
resolver
ensp
ENSP00000358107
resolver
ensp
ENSP00000498013
resolver
ensp
ENSP00000558860
resolver
ensp
ENSP00000605377
resolver
ensp
ENSP00000627200
resolver
ensp
ENSP00000654012
resolver
enst
ENST00000369111
resolver
enst
ENST00000647854
resolver
genesymbol
CA14
resolver
hgnc
HGNC:1372
resolver
uniprot
A8K3J4
resolver
uniprot
Q5TB24
resolver
uniprot
Q8NCF4
resolver
uniprot_entry
A8K3J4_HUMAN
resolver
uniprot_entry
CAH14_HUMAN
resolver
uniprot_sec
Q5TB24
resolver
uniprot_sec
Q8NCF4
resolver
activity_regulation
ACTIVITY REGULATION: Activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. Inhibited by coumarins, saccharin, and sulfonamide carbonic anhydrase inhibitors including acetazolamide (AZA) and aminobenzolamide, as well as by foscarnet (phosphonoformate trisodium salt). {ECO:0000269|PubMed:16039848, ECO:0000269|PubMed:16686544, ECO:0000269|PubMed:16807956, ECO:0000269|PubMed:17127057, ECO:0000269|PubMed:17314045, ECO:0000269|PubMed:17705204, ECO:0000269|PubMed:19186056, ECO:0000269|PubMed:19206230}.
uniprot
proteins
amino_acid_sequence
MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
uniprot
proteins
ec_number
4.2.1.1
uniprot
proteins
function
FUNCTION: Reversible hydration of carbon dioxide. {ECO:0000269|PubMed:16039848, ECO:0000269|PubMed:16686544, ECO:0000269|PubMed:16807956, ECO:0000269|PubMed:17127057, ECO:0000269|PubMed:17314045, ECO:0000269|PubMed:17705204, ECO:0000269|PubMed:19186056, ECO:0000269|PubMed:19206230}.
uniprot
proteins
mass_dalton
37668
uniprot
proteins
protein_family
Alpha-carbonic anhydrase family
uniprot
proteins
pubmed
10512682
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16039848
uniprot
proteins
pubmed
16686544
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16807956
uniprot
proteins
pubmed
17127057
uniprot
proteins
pubmed
17314045
uniprot
proteins
pubmed
17705204
uniprot
proteins
pubmed
19186056
uniprot
proteins
pubmed
19206230
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24374484
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 291..311; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins