Ccnb1
entrez
268697
canonical
uniprot
P24860
canonical
ensembl
ENSMUSG00000041431
resolver
ensp
ENSMUSP00000071989
resolver
enst
ENSMUST00000072119
resolver
genesymbol
Ccnb1
resolver
genesymbol_syn
Ccn-2
resolver
genesymbol_syn
Ccnb1-rs13
resolver
genesymbol_syn
Cycb
resolver
genesymbol_syn
Cycb1
resolver
uniprot
Q3TQW9
resolver
uniprot_entry
CCNB1_MOUSE
resolver
uniprot_entry
Q3TQW9_MOUSE
resolver
amino_acid_sequence
MALRVTRNTKINAENKAKVSMAGAKRVPVTVTAASKPGLRPRTALGDIGNKVSEELQARVPLKREAKTLGTGKGTVKALPKPVEKVPVCEPEVELAEPEPEPELEHVREEKLSPEPILVDNPSPSPMETSGCAPAEEYLCQAFSDVILAVSDVDADDGADPNLCSEYVKDIYAYLRQLEEEQSVRPKYLQGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNSCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKVGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILDNGEWTPTLQHYLSYSEDSLLPVMQHLAKNVVMVNCGLTKHMTVKNKYAASKHAKISTLAQLNCTLVQNLSKAVTKA
uniprot
proteins
function
FUNCTION: Essential for the control of the cell cycle at the G2/M (mitosis) transition (By similarity). Binds and activates cyclin-dependent protein kinase CDK1/CDC2 (By similarity). {ECO:0000250|UniProtKB:P14635}.
uniprot
proteins
mass_dalton
48052
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Deubiquitinated by USP22 during G2/M phase (By similarity). {ECO:0000250}.; PTM: Phosphorylated by PLK1 at Ser-130 on centrosomes during prophase: phosphorylation by PLK1 does not cause nuclear import. Phosphorylation at Ser-144 was also reported to be mediated by PLK1 but Ser-130 seems to be the primary phosphorylation site (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Cyclin AB subfamily
uniprot
proteins
protein_family
Cyclin family
uniprot
proteins
pubmed
12525704
uniprot
proteins
pubmed
1280449
uniprot
proteins
pubmed
1387105
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1836195
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
uniprot
proteins