Gfra4
entrez
66023
canonical
uniprot
Q9EPI2
canonical
ensembl
ENSRNOG00000021241
resolver
ensp
ENSRNOP00000042875
resolver
ensp
ENSRNOP00000106510
resolver
ensp
ENSRNOP00000109889
resolver
enst
ENSRNOT00000132677
resolver
enst
ENSRNOT00000152461
resolver
genesymbol
Gfra4
resolver
uniprot
A0ABK0LWI9
resolver
uniprot
A0ABK0M4Q0
resolver
uniprot
Q9EPI3
resolver
uniprot_entry
A0ABK0LWI9_RAT
resolver
uniprot_entry
A0ABK0M4Q0_RAT
resolver
uniprot_entry
GFRA4_RAT
resolver
uniprot_sec
Q9EPI3
resolver
amino_acid_sequence
MLSGAYLRVLNERPGQAVLWSLGCQRGSASSTEGNRCVEAAEACTADEQCQQLRSEYVAQCLGRAGWRGPGSCVRSRCRRALRRFFARGPPALTHALLFCGCEGPACAERRRQTFAPACAFSGPQLAPPSCLKPLDRCERSRRCRPRLFAFQASCAPAPGSRDGCPEEGGPRCLRAYAGLVGTVVTPNYLDNVSARVAPWCGCEASGNRREECEAFRKLFTRNPCLDGAIQAFDSSQPSVLQDQWNPYQNAGCCFLWVSSMSILTALALQALL
uniprot
proteins
function
FUNCTION: Receptor for persephin (PSPN), a growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons (PubMed:10958791). Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor (By similarity). May be important in C-cell development and, in the postnatal development of the adrenal medulla (By similarity). {ECO:0000250|UniProtKB:Q9GZZ7, ECO:0000269|PubMed:10958791}.
uniprot
proteins
mass_dalton
29682
uniprot
proteins
protein_family
GDNFR family
uniprot
proteins
pubmed
10958791
uniprot
proteins
sequence_length
273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform A]: Cell membrane {ECO:0000269|PubMed:10958791}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9GZZ7}.; SUBCELLULAR LOCATION: [Isoform B]: Secreted {ECO:0000305|PubMed:10958791}.
uniprot
proteins