Dusp3
entrez
72349
canonical
uniprot
Q9D7X3
canonical
ensembl
ENSMUSG00000003518
resolver
ensp
ENSMUSP00000003612
resolver
ensp
ENSMUSP00000102790
resolver
enst
ENSMUST00000003612
resolver
enst
ENSMUST00000107172
resolver
genesymbol
Dusp3
resolver
uniprot_entry
DUS3_MOUSE
resolver
amino_acid_sequence
MSSSFELSVQDLNDLLSDGSGCYSLPSQPCNEVVPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGIKANDTQEFNLSAYFERATDFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSTVRQNREIGPNDGFLAQLCQLNDRLAKEGKVKL
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines (PubMed:16845380). Specifically dephosphorylates and inactivates ERK1 and ERK2 (PubMed:16845380). {ECO:0000269|PubMed:16845380}.
uniprot
proteins
mass_dalton
20472
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16845380
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
37865089
uniprot
proteins
sequence_length
185
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16845380}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37865089}.
uniprot
proteins