Esrp1
entrez
207920
canonical
uniprot
Q3US41
canonical
ensembl
ENSMUSG00000040728
resolver
ensp
ENSMUSP00000037921
resolver
ensp
ENSMUSP00000103946
resolver
ensp
ENSMUSP00000103947
resolver
ensp
ENSMUSP00000103949
resolver
ensp
ENSMUSP00000288673
resolver
ensp
ENSMUSP00000330664
resolver
enst
ENSMUST00000108311
resolver
genesymbol
Esrp1
resolver
genesymbol_syn
Rbm35a
resolver
uniprot
A2AJQ4
resolver
uniprot
A2AJQ5
resolver
uniprot
A2AJQ6
resolver
uniprot
A2AJQ7
resolver
uniprot
A2AJQ8
resolver
uniprot
F8WGU3
resolver
uniprot
Q3TLQ3
resolver
uniprot
Q6PCL4
resolver
uniprot
Q8C9F5
resolver
uniprot
Q8K0G2
resolver
uniprot_entry
ESRP1_MOUSE
resolver
uniprot_entry
F8WGU3_MOUSE
resolver
uniprot_sec
A2AJQ4
resolver
uniprot_sec
A2AJQ5
resolver
uniprot_sec
A2AJQ6
resolver
uniprot_sec
A2AJQ7
resolver
uniprot_sec
A2AJQ8
resolver
uniprot_sec
Q3TLQ3
resolver
uniprot_sec
Q6PCL4
resolver
uniprot_sec
Q8C9F5
resolver
uniprot_sec
Q8K0G2
resolver
amino_acid_sequence
MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHIRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFPAPTAVIPTEAAIYQPSLLLNPRALQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLSSVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYATEDGLVHTNDQARTLPKEWVCI
uniprot
proteins
function
FUNCTION: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity). Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium (PubMed:29107558). {ECO:0000250|UniProtKB:Q6NXG1, ECO:0000269|PubMed:29107558}.
uniprot
proteins
mass_dalton
75549
uniprot
proteins
protein_family
ESRP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19285943
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29107558
uniprot
proteins
sequence_length
680
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins