Mpg
entrez
268395
canonical
uniprot
Q04841
canonical
ensembl
ENSMUSG00000020287
resolver
ensp
ENSMUSP00000020528
resolver
enst
ENSMUST00000020528
resolver
genesymbol
Mpg
resolver
genesymbol_syn
Mid1
resolver
uniprot
A2AVE7
resolver
uniprot
Q64182
resolver
uniprot_entry
3MG_MOUSE
resolver
uniprot_sec
A2AVE7
resolver
uniprot_sec
Q64182
resolver
activity_regulation
ACTIVITY REGULATION: Binding to SSBP1 in mitochondria inhibits glycosylase activity in the context of a single-stranded DNA (ssDNA), but not a double-stranded DNA (dsDNA) substrates. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MPARGGSARPGRGALKPVSVTLLPDTEQPPFLGRARRPGNARAGSLVTGYHEVGQMPAPLSRKIGQKKQRLADSEQQQTPKERLLSTPGLRRSIYFSSPEDHSGRLGPEFFDQPAVTLARAFLGQVLVRRLADGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYLIYGMYFCLNVSSQGAGACVLLRALEPLEGLETMRQLRNSLRKSTVGRSLKDRELCSGPSKLCQALAIDKSFDQRDLAQDDAVWLEHGPLESSSPAVVVAAARIGIGHAGEWTQKPLRFYVQGSPWVSVVDRVAEQMDQPQQTACSEGLLIVQK
uniprot
proteins
ec_number
3.2.2.21
uniprot
proteins
function
FUNCTION: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
uniprot
proteins
mass_dalton
36472
uniprot
proteins
protein_family
DNA glycosylase MPG family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
7832991
uniprot
proteins
pubmed
8318735
uniprot
proteins
pubmed
8435858
uniprot
proteins
pubmed
8589517
uniprot
proteins
sequence_length
333
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins