EFHD2
entrez
79180
canonical
uniprot
Q96C19
canonical
ensembl
ENSG00000142634
resolver
ensp
ENSP00000365147
resolver
ensp
ENSP00000576315
resolver
enst
ENST00000375980
resolver
genesymbol
EFHD2
resolver
genesymbol_syn
SWS1
resolver
hgnc
HGNC:28670
resolver
uniprot
A0A024QZ77
resolver
uniprot
A0A140VJI8
resolver
uniprot
Q5JYW9
resolver
uniprot_entry
A0A024QZ77_HUMAN
resolver
uniprot_entry
EFHD2_HUMAN
resolver
uniprot_sec
A0A140VJI8
resolver
uniprot_sec
Q5JYW9
resolver
amino_acid_sequence
MATDELATKLSRRLQMEGEGGGETPEQPGLNGAAAAAAGAPDEAAEALGSADCELSAKLLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLCVLARLSEIDVSSEGVKGAKSFFEAKVQAINVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQSTFK
uniprot
proteins
function
FUNCTION: May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. {ECO:0000250}.
uniprot
proteins
mass_dalton
26697
uniprot
proteins
pubmed
11788997
uniprot
proteins
pubmed
15274114
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19118655
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
240
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane raft {ECO:0000250}. Note=In a mouse immature B-cell line WEHI-231. {ECO:0000250}.
uniprot
proteins