P28309
uniprot
P28309
canonical
amino_acid_sequence
MKPLVLLSALVLLSFQVQADPIQNTDEETKTEEQSGEEDQAVSVSFGDREGASLQEESLRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR
uniprot
proteins
function
FUNCTION: Has broad-spectrum antimicrobial properties. Has antibacterial activity against the Gram-positive bacterium L.monocytogenes EGD and the Gram-negative bacteria E.coli ML-35p and avirulent S.typhimurium 7953, but not against the mouse-virulent S.typhimurium 14028S. Probably contributes to the antimicrobial barrier function of the small bowel mucosa. {ECO:0000269|PubMed:1500163}.
uniprot
proteins
mass_dalton
10560
uniprot
proteins
protein_family
Alpha-defensin family
uniprot
proteins
pubmed
1500163
uniprot
proteins
pubmed
1500431
uniprot
proteins
pubmed
8043949
uniprot
proteins
pubmed
8188287
uniprot
proteins
sequence_length
93
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins