Gldc
entrez
104174
canonical
uniprot
Q91W43
canonical
ensembl
ENSMUSG00000024827
resolver
ensp
ENSMUSP00000025778
resolver
enst
ENSMUST00000025778
resolver
genesymbol
Gldc
resolver
uniprot_entry
GCSP_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Stimulated by lipoic acid. Inhibited in presence of methylamine (By similarity). {ECO:0000250|UniProtKB:P15505}.
uniprot
proteins
amino_acid_sequence
MQLCARAWGLRLGRGAGGGHRLARGTGLSWAQRSRDSSGGGGGGGGGDRGAAGASRLLERLLPRHDDFSRRHIGPGDKDRREMLQALGLASIDELIEKTVPASIRLKRPLKMEDPICENEILETLHAIASKNQIWRSYIGMGYYNCSVPQTILRNLLENSGWVTQYTPYQPEVSQGRLESLLNYQTMVSDITGLDMANASLLDEATAAAEAMQLCHRHNKRKKFFVDPRCHPQTIAVVQTRAKYRGVLVELKLPHEMDFSGKDVCGVLFQYPDTEGKVEDFTELVDRAHQTGSLTCCATDLLALCILRPPGEFGVDIALGNSQRFGVPLGYGGPHAAFFAVKENLVRMMPGRMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSQGLKHIAKRVHNATLILSEGLKRAGHQLQHDLFFDTLKVQCGCSVKEVLGRAAQRQINFRLFDDGTLGISLDETVTEKDLDDLLWIFGCESSAELVAEGMGEERRGLLGSSFKRTSPFLTHQVFNSYHSETNLVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWREFANIHPFVPLDQAQGYQQLFQGLEKDLCEITGYDRVSFQPNSGAQGEYAGLATIRAYLDQKGERHRTVCLIPKSAHGTNPASAHMAGMKIQPVEVDRYGNIDVAHLKAMVDQHKENLAAIMITYPSTNGVFEENIGDVCALIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKKHLSPFLPSHPVISIKPTEGTWPVGTVSAAPWGSSSILPISWAYIKMMGGKGLKEATEIAILNANYMAKRLEKHYRVLFRGARGYVAHEFILDTRPFKKSANVEAVDVAKRLQDYGFHAPTMSWPVAGTLMIEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSCWDRPYSREVAAFPLPFVKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS
uniprot
proteins
ec_number
1.4.4.2
uniprot
proteins
function
FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH) (By similarity). {ECO:0000250|UniProtKB:P15505}.
uniprot
proteins
mass_dalton
113267
uniprot
proteins
protein_family
GcvP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
sequence_length
1025
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P15505}.
uniprot
proteins