B4galt6
entrez
65196
canonical
uniprot
O88419
canonical
ensembl
ENSRNOG00000015895
resolver
ensembl
ENSRNOG00055018341
resolver
ensembl
ENSRNOG00060012590
resolver
ensembl
ENSRNOG00065015185
resolver
ensp
ENSRNOP00000021764
resolver
ensp
ENSRNOP00000082568
resolver
ensp
ENSRNOP00055025125
resolver
ensp
ENSRNOP00060016865
resolver
ensp
ENSRNOP00065019702
resolver
enst
ENSRNOT00000111678
resolver
enst
ENSRNOT00055031163
resolver
enst
ENSRNOT00060021366
resolver
enst
ENSRNOT00065025162
resolver
genesymbol
B4galt6
resolver
uniprot_entry
B4GT6_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by EDTA. {ECO:0000269|PubMed:9593693}.
uniprot
proteins
amino_acid_sequence
MSALKRMMRVSNRSLIAFIFFFSLSTSCLYFIYVAPGIANTYLFMVQARGIMLRENVKTIGHMIRLYTNKNTTLNGTDYPEGNNTSDYLVQTTTYLPQNFTYSPHLPCPEKLPYMRGFLSVNVSEISFDEVHQLFSKDSEIEPGGHWRPQDCKPRWKVAVLIPFRNRHEHLPIFFLHLIPMLQKQRLEFAFYVIEQTGTQPFNRAMLFNVGFKEAMKDRAWDCVIFHDVDHLPENDRNYYGCGEMPRHFAAKLDKYMYILPYKEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVHYSGYNVTRPEGDLGKYTSIPHHHRGEVQFLGRYKLLRYSKERQFIDGLNNLLYTPKILVDRLYTNISVNLMPELAPVEDY
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
ec_number
2.4.1.274
uniprot
proteins
function
FUNCTION: Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:9593693). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). {ECO:0000250|UniProtKB:Q9WVK5, ECO:0000269|PubMed:9593693}.
uniprot
proteins
mass_dalton
44778
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.; PATHWAY: Sphingolipid metabolism.
uniprot
proteins
protein_family
Glycosyltransferase 7 family
uniprot
proteins
pubmed
9593693
uniprot
proteins
sequence_length
382
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:P15291}; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack. {ECO:0000250|UniProtKB:P15291}.
uniprot
proteins
transmembrane_region
TRANSMEM 16..35; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins