MARCHF3
entrez
115123
canonical
uniprot
Q86UD3
canonical
ensembl
ENSG00000173926
resolver
ensp
ENSP00000309141
resolver
ensp
ENSP00000598570
resolver
ensp
ENSP00000714462
resolver
genesymbol
MARCHF3
resolver
genesymbol_syn
MARCH3
resolver
genesymbol_syn
RNF173
resolver
hgnc
HGNC:28728
resolver
uniprot
A8K264
resolver
uniprot
B9EJE7
resolver
uniprot_entry
MARH3_HUMAN
resolver
uniprot_sec
A8K264
resolver
uniprot_sec
B9EJE7
resolver
amino_acid_sequence
MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVNVPSNQPSLLGLHSVKRNSKETVV
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000250|UniProtKB:Q5XIE5}.
uniprot
proteins
mass_dalton
28504
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16428329
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
253
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane {ECO:0000269|PubMed:16428329}; Multi-pass membrane protein {ECO:0000269|PubMed:16428329}. Early endosome membrane {ECO:0000269|PubMed:16428329}; Multi-pass membrane protein {ECO:0000269|PubMed:16428329}.
uniprot
proteins
transmembrane_region
TRANSMEM 145..165; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 182..202; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins