P2ry2
entrez
18442
canonical
uniprot
P35383
canonical
ensembl
ENSMUSG00000032860
resolver
ensp
ENSMUSP00000036765
resolver
ensp
ENSMUSP00000137152
resolver
ensp
ENSMUSP00000146352
resolver
ensp
ENSMUSP00000146679
resolver
enst
ENSMUST00000037540
resolver
enst
ENSMUST00000178340
resolver
enst
ENSMUST00000207916
resolver
enst
ENSMUST00000208340
resolver
genesymbol
P2ry2
resolver
genesymbol_syn
P2ru1
resolver
uniprot
A0A0R4J289
resolver
uniprot
O09031
resolver
uniprot
Q9CPZ4
resolver
uniprot_entry
A0A0R4J289_MOUSE
resolver
uniprot_entry
P2RY2_MOUSE
resolver
uniprot_sec
O09031
resolver
uniprot_sec
Q9CPZ4
resolver
amino_acid_sequence
MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
uniprot
proteins
function
FUNCTION: Receptor for ATP and UTP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.
uniprot
proteins
mass_dalton
42175
uniprot
proteins
mutagenesis
MUTAGEN 107; /note="K->I: No effect on receptor activation."; /evidence="ECO:0000269|PubMed:7876172"; MUTAGEN 110; /note="R->L: No effect on receptor activation."; /evidence="ECO:0000269|PubMed:7876172"; MUTAGEN 262; /note="H->L: Decrease in receptor activation."; /evidence="ECO:0000269|PubMed:7876172"; MUTAGEN 265; /note="R->L: Decrease in receptor activation."; /evidence="ECO:0000269|PubMed:7876172"; MUTAGEN 289; /note="K->I: No effect on receptor activation."; /evidence="ECO:0000269|PubMed:7876172"; MUTAGEN 292; /note="R->L: Decrease in receptor activation."; /evidence="ECO:0000269|PubMed:7876172
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
7685114
uniprot
proteins
pubmed
7876172
uniprot
proteins
pubmed
8739319
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 33..59; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 71..93; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 111..129; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 153..172; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 195..220; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 247..269; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 288..309; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins