MPND
entrez
84954
canonical
uniprot
Q8N594
canonical
ensembl
ENSG00000008382
resolver
ensp
ENSP00000262966
resolver
ensp
ENSP00000353015
resolver
ensp
ENSP00000471189
resolver
ensp
ENSP00000471735
resolver
enst
ENST00000599840
resolver
genesymbol
MPND
resolver
hgnc
HGNC:25934
resolver
uniprot
Q96SJ0
resolver
uniprot
Q9Y2P1
resolver
uniprot
Q9Y2P2
resolver
uniprot
W4VSR2
resolver
uniprot_entry
MPND_HUMAN
resolver
uniprot_entry
W4VSR2_HUMAN
resolver
uniprot_sec
Q96SJ0
resolver
uniprot_sec
Q9Y2P1
resolver
uniprot_sec
Q9Y2P2
resolver
amino_acid_sequence
MAAPEPLSPAGGAGEEAPEEDEDEAEAEDPERPNAGAGGGRSGGGGSSVSGGGGGGGAGAGGCGGPGGALTRRAVTLRVLLKDALLEPGAGVLSIYYLGKKFLGDLQPDGRIMWQETGQTFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKATWLRLHQLHTPATAADESPASEGEEEELLMEEEEEDVLAGVSAEDKSRRPLGKSPSEPAHPEATTPGKRVDSKIRVPVRYCMLGSRDLARNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHSHLTRSEVVGYLGGRWDVNSQMLTVLRAFPCRSRLGDAETAAAIEEEIYQSLFLRGLSLVGWYHSHPHSPALPSLQDIDAQMDYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKISPFWVMPPPEMLLVEFYKGSPDLVRLQEPWSQEHTYLDKLKISLASRTPKDQSLCHVLEQVCGVLKQGS
uniprot
proteins
ec_number
3.4.-.-
uniprot
proteins
function
FUNCTION: Probable protease (By similarity). Acts as a sensor of N(6)-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation (PubMed:30982744). Binds only double strand DNA (dsDNA) in a sequence-independent manner (By similarity). {ECO:0000250|UniProtKB:Q3TV65, ECO:0000250|UniProtKB:Q5VVJ2, ECO:0000269|PubMed:30982744}.
uniprot
proteins
mass_dalton
50662
uniprot
proteins
post_translational_modification
PTM: Degraded following binding to N(6)-methyladenosine methylated DNA (m6A). {ECO:0000269|PubMed:30982744}.
uniprot
proteins
protein_family
Peptidase M67 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
30982744
uniprot
proteins
sequence_length
471
uniprot
proteins