TAX1BP3
entrez
30851
canonical
uniprot
O14907
canonical
ensembl
ENSG00000213977
resolver
ensp
ENSP00000225525
resolver
ensp
ENSP00000484776
resolver
enst
ENST00000225525
resolver
enst
ENST00000611779
resolver
genesymbol
TAX1BP3
resolver
genesymbol_syn
TIP1
resolver
hgnc
HGNC:30684
resolver
uniprot
A0A087X282
resolver
uniprot
B2RD53
resolver
uniprot
D3DTJ6
resolver
uniprot
Q7LCQ4
resolver
uniprot_entry
A0A087X282_HUMAN
resolver
uniprot_entry
TX1B3_HUMAN
resolver
uniprot_sec
B2RD53
resolver
uniprot_sec
D3DTJ6
resolver
uniprot_sec
Q7LCQ4
resolver
amino_acid_sequence
MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS
uniprot
proteins
function
FUNCTION: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:16855024, ECO:0000269|PubMed:21139582}.
uniprot
proteins
mass_dalton
13735
uniprot
proteins
mutagenesis
MUTAGEN 20; /note="K->A: Abolishes interaction with KCNJ4."; /evidence="ECO:0000269|PubMed:16855024"; MUTAGEN 90; /note="H->A: Abolishes interaction with KCNJ4."; /evidence="ECO:0000269|PubMed:16855024
uniprot
proteins
pubmed
10673275
uniprot
proteins
pubmed
10940294
uniprot
proteins
pubmed
11163757
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16855024
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19635485
uniprot
proteins
pubmed
19685007
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21139582
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21417405
uniprot
proteins
pubmed
21787750
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25645515
uniprot
proteins
pubmed
9482110
uniprot
proteins
sequence_length
124
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins.
uniprot
proteins