Acot4
entrez
171282
canonical
uniprot
Q8BWN8
canonical
ensembl
ENSMUSG00000052392
resolver
ensp
ENSMUSP00000021652
resolver
ensp
ENSMUSP00000160747
resolver
enst
ENSMUST00000021652
resolver
genesymbol
Acot4
resolver
genesymbol_syn
Pte1b
resolver
genesymbol_syn
Pte2b
resolver
uniprot
Q14DI6
resolver
uniprot
Q8BJQ1
resolver
uniprot
Q8BL20
resolver
uniprot
Q9QYR8
resolver
uniprot_entry
ACOT4_MOUSE
resolver
uniprot_entry
Q14DI6_MOUSE
resolver
uniprot_sec
Q8BJQ1
resolver
uniprot_sec
Q8BL20
resolver
uniprot_sec
Q9QYR8
resolver
amino_acid_sequence
MAATLSVEPTGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARVPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFLVELEVLDGHEPDGGRRLARTVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGIIDVYGVGGGLLEYRAGLVAGHGFATLALAFYDFEDLPKELNVIEVDYFEEAVRYMLRHPKVKGPDIGLLGLSLGADVCLIMASFLNNVSATVSINGSAFSGNRHIKYKQTMIPPLGHDLRRMKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELYTQIASDRLQAHGKERPQVLSYPGTGHYIEPPYFPMCPASLHKIVNEAVIWGGEVKAHSKAQIDAWKQILFFFGKHLGSTHSRASCRL
uniprot
proteins
ec_number
3.1.2.3
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16141203, PubMed:16940157). In contrast to its human ortholog, functions essentially as a succinyl-CoA thioesterase with no activity with medium to long chain saturated acyl-CoAs and with a low activity toward glutaryl-CoA (PubMed:16141203, PubMed:16940157). {ECO:0000269|PubMed:16141203, ECO:0000269|PubMed:16940157}.
uniprot
proteins
mass_dalton
46481
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid metabolism. {ECO:0000305|PubMed:16141203, ECO:0000305|PubMed:16940157}.
uniprot
proteins
protein_family
C/M/P thioester hydrolase family
uniprot
proteins
pubmed
10567408
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16141203
uniprot
proteins
pubmed
16940157
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
421
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000269|PubMed:16141203}.
uniprot
proteins