CNMD
entrez
11061
canonical
uniprot
O75829
canonical
ensembl
ENSG00000136110
resolver
ensp
ENSP00000367198
resolver
ensp
ENSP00000388576
resolver
ensp
ENSP00000533346
resolver
ensp
ENSP00000586525
resolver
ensp
ENSP00000586527
resolver
ensp
ENSP00000586528
resolver
ensp
ENSP00000732148
resolver
genesymbol
CNMD
resolver
genesymbol_syn
CHMI
resolver
genesymbol_syn
LECT1
resolver
genesymbol_syn
MYETS1
resolver
hgnc
HGNC:17005
resolver
uniprot
Q5TAM4
resolver
uniprot
Q8TAY6
resolver
uniprot
Q9UM18
resolver
uniprot_entry
CNMD_HUMAN
resolver
uniprot_sec
Q5TAM4
resolver
uniprot_sec
Q8TAY6
resolver
uniprot_sec
Q9UM18
resolver
amino_acid_sequence
MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
uniprot
proteins
function
FUNCTION: Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization. {ECO:0000269|PubMed:16980969}.
uniprot
proteins
mass_dalton
37102
uniprot
proteins
post_translational_modification
PTM: After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
uniprot
proteins
protein_family
Chondromodulin-1 family
uniprot
proteins
pubmed
10103018
uniprot
proteins
pubmed
10570955
uniprot
proteins
pubmed
10912526
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16980969
uniprot
proteins
pubmed
9731231
uniprot
proteins
sequence_length
334
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Chondromodulin-1]: Secreted, extracellular space, extracellular matrix. Note=Accumulated in the inter-territorial matrix of cartilage.; SUBCELLULAR LOCATION: [Chondrosurfactant protein]: Endomembrane system {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins