GRM3
entrez
2913
canonical
uniprot
Q14832
canonical
ensembl
ENSG00000198822
resolver
ensp
ENSP00000355316
resolver
ensp
ENSP00000398767
resolver
genesymbol
GRM3
resolver
genesymbol_syn
GPRC1C
resolver
genesymbol_syn
MGLUR3
resolver
hgnc
HGNC:4595
resolver
uniprot
A4D1D0
resolver
uniprot
Q2PNZ6
resolver
uniprot
Q75MV4
resolver
uniprot
Q75N17
resolver
uniprot
Q86YG6
resolver
uniprot
Q8TBH9
resolver
uniprot_entry
A4D1D0_HUMAN
resolver
uniprot_entry
GRM3_HUMAN
resolver
uniprot_sec
Q2PNZ6
resolver
uniprot_sec
Q75MV4
resolver
uniprot_sec
Q75N17
resolver
uniprot_sec
Q86YG6
resolver
uniprot_sec
Q8TBH9
resolver
amino_acid_sequence
MKMLTRLQVLTLALFSKGFLLSLGDHNFLRREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNHRRVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLADEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNVVTHRLHLNRFSVSGTGTTYSQSSASTYVPTVCNGREVLDSTTSSL
uniprot
proteins
function
FUNCTION: G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:8840013}.
uniprot
proteins
mass_dalton
98879
uniprot
proteins
protein_family
G protein-coupled receptor 3 family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16417579
uniprot
proteins
pubmed
8840013
uniprot
proteins
sequence_length
879
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:8840013}; Multi-pass membrane protein {ECO:0000269|PubMed:8840013}.
uniprot
proteins
transmembrane_region
TRANSMEM 577..599; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 614..634; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 646..664; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 689..709; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 735..756; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 770..792; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 803..828; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins