RXFP1
entrez
59350
canonical
uniprot
Q9HBX9
canonical
ensembl
ENSG00000171509
resolver
ensp
ENSP00000303248
resolver
ensp
ENSP00000345889
resolver
ensp
ENSP00000405841
resolver
ensp
ENSP00000414885
resolver
ensp
ENSP00000420712
resolver
ensp
ENSP00000423306
resolver
ensp
ENSP00000480522
resolver
ensp
ENSP00000549841
resolver
ensp
ENSP00000715049
resolver
enst
ENST00000423548
resolver
enst
ENST00000448688
resolver
enst
ENST00000460056
resolver
enst
ENST00000613319
resolver
genesymbol
RXFP1
resolver
genesymbol_syn
LGR7
resolver
hgnc
HGNC:19718
resolver
uniprot
A0A087WWV0
resolver
uniprot
A0A0A0MSX0
resolver
uniprot
A0A0A0MT52
resolver
uniprot
B3KV27
resolver
uniprot
B4DGP2
resolver
uniprot
B4DHD1
resolver
uniprot
B4DTV2
resolver
uniprot
E9PCA3
resolver
uniprot
Q2M215
resolver
uniprot
Q3KU24
resolver
uniprot
Q3KU25
resolver
uniprot
Q3KU26
resolver
uniprot
Q59H16
resolver
uniprot_entry
A0A087WWV0_HUMAN
resolver
uniprot_entry
A0A0A0MSX0_HUMAN
resolver
uniprot_entry
A0A0A0MT52_HUMAN
resolver
uniprot_entry
B3KV27_HUMAN
resolver
uniprot_entry
B4DGP2_HUMAN
resolver
uniprot_entry
E9PCA3_HUMAN
resolver
uniprot_entry
Q59H16_HUMAN
resolver
uniprot_entry
RXFP1_HUMAN
resolver
uniprot_sec
B4DHD1
resolver
uniprot_sec
B4DTV2
resolver
uniprot_sec
Q2M215
resolver
uniprot_sec
Q3KU24
resolver
uniprot_sec
Q3KU25
resolver
uniprot_sec
Q3KU26
resolver
amino_acid_sequence
MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADEDNCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
uniprot
proteins
function
FUNCTION: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
uniprot
proteins
mass_dalton
86975
uniprot
proteins
mutagenesis
MUTAGEN 637; /note="D->Y: Leads to constitutive increase of basal cAMP."; /evidence="ECO:0000269|PubMed:10935549
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10935549
uniprot
proteins
pubmed
11517286
uniprot
proteins
pubmed
12506116
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16051677
uniprot
proteins
pubmed
17148455
uniprot
proteins
pubmed
18533687
uniprot
proteins
pubmed
24014093
uniprot
proteins
sequence_length
757
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16051677}; Multi-pass membrane protein {ECO:0000269|PubMed:16051677}.
uniprot
proteins
transmembrane_region
TRANSMEM 410..430; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 444..464; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 487..507; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 528..548; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 578..598; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 630..650; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 652..672; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins