Apobec3
entrez
80287
canonical
uniprot
Q99J72
canonical
ensembl
ENSMUSG00000009585
resolver
ensp
ENSMUSP00000023054
resolver
ensp
ENSMUSP00000105249
resolver
ensp
ENSMUSP00000132391
resolver
ensp
ENSMUSP00000135079
resolver
enst
ENSMUST00000023054
resolver
enst
ENSMUST00000109620
resolver
enst
ENSMUST00000165537
resolver
genesymbol
Apobec3
resolver
genesymbol_syn
APOBEC3
resolver
uniprot
A0A2I3BNY6
resolver
uniprot
E9QMH1
resolver
uniprot
F8WJK5
resolver
uniprot
H3BJL0
resolver
uniprot
Q3TI69
resolver
uniprot
Q3U5C5
resolver
uniprot
Q8C7L0
resolver
uniprot
Q8C8V7
resolver
uniprot_entry
A0A2I3BNY6_MOUSE
resolver
uniprot_entry
ABEC3_MOUSE
resolver
uniprot_entry
E9QMH1_MOUSE
resolver
uniprot_entry
F8WJK5_MOUSE
resolver
uniprot_entry
Q3TI69_MOUSE
resolver
uniprot_entry
Q3U5C5_MOUSE
resolver
uniprot_sec
H3BJL0
resolver
uniprot_sec
Q8C7L0
resolver
uniprot_sec
Q8C8V7
resolver
amino_acid_sequence
MQPQRLGPRAGMGPFCLGCSHRKCYSPIRNLISQETFKFHFKNLGYAKGRKDTFLCYEVTRKDCDSPVSLHHGVFKNKDNIHAEICFLYWFHDKVLKVLSPREEFKITWYMSWSPCFECAEQIVRFLATHHNLSLDIFSSRLYNVQDPETQQNLCRLVQEGAQVAAMDLYEFKKCWKKFVDNGGRRFRPWKRLLTNFRYQDSKLQEILRPCYISVPSSSSSTLSNICLTKGLPETRFWVEGRRMDPLSEEEFYSQFYNQRVKHLCYYHRMKPYLCYQLEQFNGQAPLKGCLLSEKGKQHAEILFLDKIRSMELSQVTITCYLTWSPCPNCAWQLAAFKRDRPDLILHIYTSRLYFHWKRPFQKGLCSLWQSGILVDVMDLPQFTDCWTNFVNPKRPFWPWKGLEIISRRTQRRLRRIKESWGLQDLVNDFGNLQLGPPMS
uniprot
proteins
ec_number
3.5.4.38
uniprot
proteins
function
FUNCTION: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity against HIV-1, simian immunodeficiency viruses (SIVs), mouse mammary tumor virus (MMTV) and friend murine leukemia virus (FrMLV) and may inhibit the mobility of LTR retrotransposons. {ECO:0000269|PubMed:16378963, ECO:0000269|PubMed:16527742, ECO:0000269|PubMed:17259974, ECO:0000269|PubMed:18786991}.
uniprot
proteins
mass_dalton
52213
uniprot
proteins
mutagenesis
MUTAGEN 84; /note="E->A: Decrease in cytidine deaminase and antiviral activity."; /evidence="ECO:0000269|PubMed:17020885"; MUTAGEN 84; /note="E->A: Decrease in cytidine deaminase and antiviral activity; when associated with A-301."; /evidence="ECO:0000269|PubMed:17020885"; MUTAGEN 301; /note="E->A: Decrease in cytidine deaminase and antiviral activity; when associated with A-84."; /evidence="ECO:0000269|PubMed:17020885"; MUTAGEN 301; /note="E->A: No effect on cytidine deaminase and antiviral activity."; /evidence="ECO:0000269|PubMed:17020885
uniprot
proteins
protein_family
Cytidine and deoxycytidylate deaminase family
uniprot
proteins
pubmed
12859895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16378963
uniprot
proteins
pubmed
16527742
uniprot
proteins
pubmed
17020885
uniprot
proteins
pubmed
17259974
uniprot
proteins
pubmed
18304004
uniprot
proteins
pubmed
18786991
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
440
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16527742}.
uniprot
proteins