Dguok
entrez
27369
canonical
uniprot
Q9QX60
canonical
ensembl
ENSMUSG00000014554
resolver
ensp
ENSMUSP00000014698
resolver
ensp
ENSMUSP00000109520
resolver
enst
ENSMUST00000113888
resolver
genesymbol
Dguok
resolver
genesymbol_syn
Dgk
resolver
uniprot
F6UU70
resolver
uniprot
Q504N4
resolver
uniprot
Q8CBU2
resolver
uniprot
Q9R0Y2
resolver
uniprot
Q9WUT9
resolver
uniprot_entry
DGUOK_MOUSE
resolver
uniprot_entry
F6UU70_MOUSE
resolver
uniprot_entry
Q504N4_MOUSE
resolver
uniprot_sec
Q8CBU2
resolver
uniprot_sec
Q9R0Y2
resolver
uniprot_sec
Q9WUT9
resolver
amino_acid_sequence
MAAGRFLLRRLRASFRSPLRNALVDAPHARAMHDGGGPRRLCIEGNIAVGKSTFVKLLMKTHPEWQVATEPIAEWQNIQAAGAQKDGTSKRLGNLLEMMYQEPARWSYTFQTLSFMSRLKVQLEPIPGRLLQAEKSVRVFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLQEFANRLLLHGFIYLQASPQVCMERLYQRDREEEKGIELAYLQQLHSQHEDWFINKTTKLHFEALQHVPVLVLDVTEDFSENAARQEELMGQVNTFMRNL
uniprot
proteins
ec_number
2.7.1.113
uniprot
proteins
ec_number
2.7.1.76
uniprot
proteins
function
FUNCTION: Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine (PubMed:10455141). In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs (PubMed:10455141). Widely used as target of antiviral and chemotherapeutic agents. {ECO:0000250|UniProtKB:Q16854, ECO:0000269|PubMed:10455141}.
uniprot
proteins
mass_dalton
32281
uniprot
proteins
protein_family
DCK/DGK family
uniprot
proteins
pubmed
10455141
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
277
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:10455141}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:10455141}.
uniprot
proteins