Crxos
entrez
546024
canonical
uniprot
Q3UL53
canonical
ensembl
ENSMUSG00000074365
resolver
genesymbol
Crxos
resolver
genesymbol_syn
AY590891
resolver
genesymbol_syn
Crxos1
resolver
uniprot
B6ZND8
resolver
uniprot
B6ZND9
resolver
uniprot
Q3UEY5
resolver
uniprot_entry
CRXOS_MOUSE
resolver
uniprot_entry
Q3UEY5_MOUSE
resolver
uniprot_sec
B6ZND8
resolver
uniprot_sec
B6ZND9
resolver
amino_acid_sequence
MEASPRSLTSCTLGPLDQKFSWEQLSELEAYFKVEPYPDLQDRKIMATRLKLKEEQVEAWFIQRSLEEEMRPPLARLQQSALDGTSSPSHKALCCRPPSWKYRLIPINPPESSTSCLKDSKTVLISKTELTDEQFQKLRKHFETDRCPNEETLQAFAEELKLRKDLIRSWFITQRHRMRGYRRLFMRYYRDWKTSREYSTTRSFDRQKNSKECSQNDPGLPEALEALKRLKLSSGYQSRDGMSQDF
uniprot
proteins
function
FUNCTION: Transcription factor that acts as a regulator of embryonic stem cell differentiation during the preimplantation stages of embryonic development. {ECO:0000269|PubMed:20018908, ECO:0000269|PubMed:22608553, ECO:0000269|PubMed:29423137}.; FUNCTION: [Isoform 1]: Transcription factor that acts as a positive regulator of embryonic stem cell differentiation. {ECO:0000269|PubMed:20018908}.; FUNCTION: [Isoform 2]: Transcription factor that promotes embryonic stem cell pluripotency. {ECO:0000269|PubMed:19800316, ECO:0000269|PubMed:20018908, ECO:0000269|PubMed:25817697, ECO:0000269|PubMed:26983934}.; FUNCTION: [Isoform 3]: Transcription factor that promotes embryonic stem cell pluripotency (PubMed:22367590, PubMed:22785471). Also involved in extraembryonic tissues development by promoting the expression of placental prolactin family genes (PubMed:21084569). {ECO:0000269|PubMed:21084569, ECO:0000269|PubMed:22367590, ECO:0000269|PubMed:22785471}.
uniprot
proteins
mass_dalton
29090
uniprot
proteins
mutagenesis
MUTAGEN 163..177; /note="RKDLIRSWFITQRHR->AADLIASWFITQAHA: Strongly reduced nuclear localization."; /evidence="ECO:0000269|PubMed:23510645
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19800316
uniprot
proteins
pubmed
20018908
uniprot
proteins
pubmed
21084569
uniprot
proteins
pubmed
22367590
uniprot
proteins
pubmed
22608553
uniprot
proteins
pubmed
22785471
uniprot
proteins
pubmed
23510645
uniprot
proteins
pubmed
25817697
uniprot
proteins
pubmed
26983934
uniprot
proteins
pubmed
29423137
uniprot
proteins
sequence_length
246
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:23510645}.
uniprot
proteins