MMP15
entrez
4324
canonical
uniprot
P51511
canonical
ensembl
ENSG00000102996
resolver
ensp
ENSP00000219271
resolver
enst
ENST00000219271
resolver
genesymbol
MMP15
resolver
hgnc
HGNC:7161
resolver
uniprot
A0A2U6
resolver
uniprot
Q14111
resolver
uniprot_entry
MMP15_HUMAN
resolver
uniprot_sec
A0A2U6
resolver
uniprot_sec
Q14111
resolver
amino_acid_sequence
MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKRSLQEWV
uniprot
proteins
ec_number
3.4.24.-
uniprot
proteins
function
FUNCTION: Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. {ECO:0000269|PubMed:9461298}.
uniprot
proteins
mass_dalton
75807
uniprot
proteins
post_translational_modification
PTM: The precursor is cleaved by a furin endopeptidase. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase M10A family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
7649159
uniprot
proteins
pubmed
9119382
uniprot
proteins
pubmed
9461298
uniprot
proteins
sequence_length
669
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}; Extracellular side {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 626..646; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins