MAFF
entrez
23764
canonical
uniprot
Q9ULX9
canonical
ensembl
ENSG00000185022
resolver
ensp
ENSP00000345393
resolver
ensp
ENSP00000391589
resolver
ensp
ENSP00000416493
resolver
ensp
ENSP00000442060
resolver
genesymbol
MAFF
resolver
hgnc
HGNC:6780
resolver
uniprot
B4DV49
resolver
uniprot
Q9Y525
resolver
uniprot_entry
MAFF_HUMAN
resolver
uniprot_sec
B4DV49
resolver
uniprot_sec
Q9Y525
resolver
amino_acid_sequence
MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS
uniprot
proteins
function
FUNCTION: Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:8932385). However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene (PubMed:16549056, PubMed:8932385). May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition (PubMed:10527846). {ECO:0000269|PubMed:10527846, ECO:0000269|PubMed:16549056, ECO:0000269|PubMed:8932385}.
uniprot
proteins
mass_dalton
17760
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
protein_family
Maf subfamily
uniprot
proteins
pubmed
10527846
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
11772409
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16549056
uniprot
proteins
pubmed
8932385
uniprot
proteins
sequence_length
164
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins