Slc7a1
entrez
11987
canonical
uniprot
Q09143
canonical
ensembl
ENSMUSG00000041313
resolver
ensp
ENSMUSP00000046714
resolver
ensp
ENSMUSP00000117781
resolver
enst
ENSMUST00000048116
resolver
genesymbol
Slc7a1
resolver
genesymbol_syn
Atrc1
resolver
genesymbol_syn
Rec-1
resolver
uniprot
P30824
resolver
uniprot
Q3TQZ8
resolver
uniprot
Q3UGD6
resolver
uniprot_entry
CTR1_MOUSE
resolver
uniprot_entry
Q3TQZ8_MOUSE
resolver
uniprot_entry
Q3UGD6_MOUSE
resolver
uniprot_sec
P30824
resolver
amino_acid_sequence
MGCKNLLGLGQQMLRRKVVDCSREESRLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIVVSGFVKGSIKNWQLTEKNFSCNNNDTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDIDSPLPGAFKHQGWEEAKYAVAIGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFKFLAKINNRTKTPVIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMARTTEELDRVDQNELVSASESQTGFLPVAEKFSLKSILSPKNVEPSKFSGLIVNISAGLLAALIITVCIVAVLGREALAEGTLWAVFVMTGSVLLCMLVTGIIWRQPESKTKLSFKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIGFTIYFGYGIWHSEEASLAAGQAKTPDSNLDQCK
uniprot
proteins
function
FUNCTION: High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. {ECO:0000269|PubMed:1652100, ECO:0000269|PubMed:1908564, ECO:0000269|PubMed:9174363}.; FUNCTION: (Microbial infection) Acts as a receptor for the ecotropic murine retroviral leukemia virus. {ECO:0000269|PubMed:1908564, ECO:0000269|PubMed:2541919}.
uniprot
proteins
mass_dalton
67092
uniprot
proteins
protein_family
Amino acid-polyamine-organocation (APC) superfamily
uniprot
proteins
protein_family
Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
uniprot
proteins
pubmed
1652100
uniprot
proteins
pubmed
1908564
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22081021
uniprot
proteins
pubmed
2541919
uniprot
proteins
pubmed
25683716
uniprot
proteins
pubmed
28973536
uniprot
proteins
pubmed
9174363
uniprot
proteins
sequence_length
622
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:25683716, ECO:0000269|PubMed:28973536}; Multi-pass membrane protein {ECO:0000255}. Note=In the absence of SCO1 in cardiomyocytes a mislocalization to the cytoplasm is seen. {ECO:0000269|PubMed:28973536}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..57; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 62..82; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 163..183; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 192..212; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 240..260; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 281..300; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 331..351; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 378..398; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 402..422; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 486..506; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 520..544; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 553..573; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 578..598; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins