Trim2
entrez
80890
canonical
uniprot
Q9ESN6
canonical
ensembl
ENSMUSG00000027993
resolver
ensp
ENSMUSP00000049902
resolver
ensp
ENSMUSP00000069922
resolver
ensp
ENSMUSP00000103319
resolver
ensp
ENSMUSP00000103320
resolver
ensp
ENSMUSP00000103321
resolver
ensp
ENSMUSP00000103323
resolver
ensp
ENSMUSP00000168501
resolver
ensp
ENSMUSP00000168507
resolver
ensp
ENSMUSP00000168510
resolver
ensp
ENSMUSP00000168515
resolver
ensp
ENSMUSP00000168517
resolver
ensp
ENSMUSP00000168536
resolver
ensp
ENSMUSP00000168543
resolver
enst
ENSMUST00000054990
resolver
enst
ENSMUST00000065380
resolver
enst
ENSMUST00000107691
resolver
enst
ENSMUST00000107692
resolver
enst
ENSMUST00000107693
resolver
enst
ENSMUST00000107695
resolver
genesymbol
Trim2
resolver
genesymbol_syn
Kiaa0517
resolver
genesymbol_syn
Narf
resolver
uniprot
E9QKC6
resolver
uniprot
F6UAI9
resolver
uniprot
Q3UHH4
resolver
uniprot
Q3UHP5
resolver
uniprot
Q5DU27
resolver
uniprot
Q8C981
resolver
uniprot_entry
E9QKC6_MOUSE
resolver
uniprot_entry
F6UAI9_MOUSE
resolver
uniprot_entry
Q3UHH4_MOUSE
resolver
uniprot_entry
TRIM2_MOUSE
resolver
uniprot_sec
Q3UHP5
resolver
uniprot_sec
Q5DU27
resolver
uniprot_sec
Q8C981
resolver
amino_acid_sequence
MASEGASIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNGEDSSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits new world arenavirus infection independently of its ubiquitin ligase activity by decreasing virus internalization (PubMed:30726215). {ECO:0000269|PubMed:18687884, ECO:0000269|PubMed:21478148, ECO:0000269|PubMed:30726215}.
uniprot
proteins
mass_dalton
81445
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
post_translational_modification
PTM: RING-type zinc finger-dependent and UBE2D1-dependent autoubiquitination. {ECO:0000269|PubMed:18687884}.
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
11331580
uniprot
proteins
pubmed
11432975
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18687884
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21478148
uniprot
proteins
pubmed
30726215
uniprot
proteins
sequence_length
744
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11432975, ECO:0000269|PubMed:30726215}.
uniprot
proteins