TTLL9
entrez
164395
canonical
uniprot
Q3SXZ7
canonical
ensembl
ENSG00000131044
resolver
ensp
ENSP00000442515
resolver
ensp
ENSP00000483865
resolver
enst
ENST00000620043
resolver
genesymbol
TTLL9
resolver
genesymbol_syn
C20orf125
resolver
hgnc
HGNC:16118
resolver
uniprot
A0A087X135
resolver
uniprot
A6NH06
resolver
uniprot
A6NIS5
resolver
uniprot
B3KSG8
resolver
uniprot
Q3SXZ8
resolver
uniprot
Q5JYS3
resolver
uniprot
Q5JYS4
resolver
uniprot_entry
A0A087X135_HUMAN
resolver
uniprot_entry
TTLL9_HUMAN
resolver
uniprot_sec
A6NH06
resolver
uniprot_sec
A6NIS5
resolver
uniprot_sec
B3KSG8
resolver
uniprot_sec
Q3SXZ8
resolver
uniprot_sec
Q5JYS3
resolver
uniprot_sec
Q5JYS4
resolver
amino_acid_sequence
MVPSREALLGPGTTAIRCPKKLQNQNYKGHGLSKGKEREQRASIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIENPYLIGGRKFDLRVYVLVMSVFAECLLWSGHRRQDVHLTNVAVQKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGREKRVGGFDLMWNDGPVSREEGAPDLSGMGNFVTNTHLGCVNDRKKQLRQLFCSLQVQKKASS
uniprot
proteins
ec_number
6.3.2.-
uniprot
proteins
function
FUNCTION: Probable tubulin polyglutamylase that generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins. Similar to TTLL1, may acquire enzymatic activity only in complex with other proteins as it is most likely lacking domains important for autonomous activity. Mediates tubulin polyglutamylation which induces establishment of microtubule heterogeneity in sperm flagella, thereby playing a role in normal motile flagella axoneme structure and sperm flagella beating pattern. {ECO:0000250|UniProtKB:A2APC3}.
uniprot
proteins
mass_dalton
51472
uniprot
proteins
protein_family
Tubulin--tyrosine ligase family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
439
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A2APC3}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A2APC3}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A2APC3}.
uniprot
proteins