Faf1
entrez
14084
canonical
uniprot
P54731
canonical
ensembl
ENSMUSG00000010517
resolver
ensp
ENSMUSP00000099785
resolver
ensp
ENSMUSP00000280488
resolver
enst
ENSMUST00000102724
resolver
genesymbol
Faf1
resolver
uniprot
Q6P1F8
resolver
uniprot_entry
FAF1_MOUSE
resolver
uniprot_sec
Q6P1F8
resolver
amino_acid_sequence
MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSDFGGETMPGPTFDPASHPAPASTPSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDSCTVGEIKQILENELQIPVPKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTVQEVKRNVYDLTSIPVRHQLWEGWPASATDDSMCLAESGLSYPCHRLTVGRRTSPVQTREQSEEQSTDVHMVSDSDGDDFEDASEFGVDDGEVFGMASSTLRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDTNRARFLTMCNRHFGSVIAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFSAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVNLFPQETLFLQAKE
uniprot
proteins
function
FUNCTION: Ubiquitin-binding protein (By similarity). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (By similarity). Potentiates but cannot initiate FAS-induced apoptosis (PubMed:8524870). {ECO:0000250|UniProtKB:Q9UNN5, ECO:0000269|PubMed:8524870}.
uniprot
proteins
mass_dalton
73863
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8524870
uniprot
proteins
sequence_length
649
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9UNN5}.
uniprot
proteins