FXYD2
entrez
486
canonical
uniprot
P54710
canonical
ensembl
ENSG00000137731
resolver
ensp
ENSP00000260287
resolver
ensp
ENSP00000292079
resolver
genesymbol
FXYD2
resolver
genesymbol_syn
ATP1C
resolver
genesymbol_syn
ATP1G1
resolver
hgnc
HGNC:4026
resolver
uniprot
Q15332
resolver
uniprot
Q53YC1
resolver
uniprot
Q9GZP3
resolver
uniprot
Q9GZQ7
resolver
uniprot_entry
ATNG_HUMAN
resolver
uniprot_sec
Q15332
resolver
uniprot_sec
Q53YC1
resolver
uniprot_sec
Q9GZP3
resolver
uniprot_sec
Q9GZQ7
resolver
amino_acid_sequence
MTGLSMDGGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDEP
uniprot
proteins
disease_involvement
DISEASE: Hypomagnesemia 2 (HOMG2) [MIM:154020]: A disorder due to primary renal wasting of magnesium. Plasma levels of other electrolytes are normal. The only abnormality found, in addition to low magnesium levels, is lowered renal excretion of calcium resulting in hypocalciuria. {ECO:0000269|PubMed:11062458}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
uniprot
proteins
mass_dalton
7283
uniprot
proteins
protein_family
FXYD family
uniprot
proteins
pubmed
11062458
uniprot
proteins
pubmed
11112438
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9048881
uniprot
proteins
sequence_length
66
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 29..46; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins