TNFRSF6B
entrez
8771
canonical
uniprot
O95407
canonical
ensembl
ENSG00000243509
resolver
ensp
ENSP00000359013
resolver
ensp
ENSP00000548561
resolver
ensp
ENSP00000548562
resolver
enst
ENST00000369996
resolver
enst
ENST00000878502
resolver
enst
ENST00000878503
resolver
genesymbol
TNFRSF6B
resolver
genesymbol_syn
DCR3
resolver
genesymbol_syn
TR6
resolver
hgnc
HGNC:11921
resolver
uniprot_entry
TNF6B_HUMAN
resolver
amino_acid_sequence
MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
uniprot
proteins
function
FUNCTION: Soluble decoy receptor that binds and neutralizes the TNF-family ligands TNFSF14/LIGHT, TNFSF15, and FASLG, preventing them from interacting with their cognate receptors and thereby blocking apoptosis and other immune-signaling pathway. {ECO:0000269|PubMed:10318773, ECO:0000269|PubMed:11390428, ECO:0000269|PubMed:21300286, ECO:0000269|PubMed:25087510, ECO:0000269|PubMed:27806260, ECO:0000269|PubMed:9872321}.
uniprot
proteins
mass_dalton
32680
uniprot
proteins
pubmed
10318773
uniprot
proteins
pubmed
10655513
uniprot
proteins
pubmed
11390428
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21300286
uniprot
proteins
pubmed
25087510
uniprot
proteins
pubmed
27806260
uniprot
proteins
pubmed
9872321
uniprot
proteins
sequence_length
300
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10318773}.
uniprot
proteins