BICDL1
entrez
92558
canonical
uniprot
Q6ZP65
canonical
ensembl
ENSG00000135127
resolver
ensp
ENSP00000380690
resolver
ensp
ENSP00000447477
resolver
ensp
ENSP00000596911
resolver
ensp
ENSP00000629934
resolver
ensp
ENSP00000758336
resolver
enst
ENST00000548673
resolver
genesymbol
BICDL1
resolver
genesymbol_syn
BICDR1
resolver
genesymbol_syn
CCDC64
resolver
hgnc
HGNC:28095
resolver
uniprot
A8MUC8
resolver
uniprot
B4DWL0
resolver
uniprot
B5MDJ0
resolver
uniprot
H0YHP2
resolver
uniprot
O95000
resolver
uniprot_entry
BICL1_HUMAN
resolver
uniprot_entry
H0YHP2_HUMAN
resolver
uniprot_sec
A8MUC8
resolver
uniprot_sec
B4DWL0
resolver
uniprot_sec
B5MDJ0
resolver
uniprot_sec
O95000
resolver
amino_acid_sequence
MSAFCLGLVGRASAPAEPDSACCMELPAAAGDAVRSPAAAAALIFPGGSGELELALEEELALLAAGERPSDPGEHPQAEPGSLAEGAGPQPPPSQDPELLSVIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELESDVKQLQDELERQQIHLREADREKSRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALREDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSCRQLQVKVEELTEERSLQSSAATSTSLLSEIEQSMEAEELEQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRTALNELKRLIQSIVDGMEPTVTLLSVEMTALKEERDRLRVTSEDKEPKEQLQKAIRDRDEAIAKKNAVELELAKCRMDMMSLNSQLLDAIQQKLNLSQQLEAWQDDMHRVIDRQLMDTHLKERSQPAAALCRGHSAGRGDEPSIAEGKRLFSFFRKI
uniprot
proteins
function
FUNCTION: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor. Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis. {ECO:0000250|UniProtKB:A0JNT9}.
uniprot
proteins
mass_dalton
64841
uniprot
proteins
protein_family
BICDR family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16541075
uniprot
proteins
sequence_length
573
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0JNT9}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:A0JNT9}. Note=Localizes around the centrosome. {ECO:0000250|UniProtKB:A0JNT9}.
uniprot
proteins