TBC1D2
entrez
55357
canonical
uniprot
Q9BYX2
canonical
ensembl
ENSG00000095383
resolver
ensp
ENSP00000364203
resolver
ensp
ENSP00000364205
resolver
ensp
ENSP00000364207
resolver
ensp
ENSP00000481721
resolver
ensp
ENSP00000677757
resolver
ensp
ENSP00000736352
resolver
genesymbol
TBC1D2
resolver
genesymbol_syn
PARIS1
resolver
genesymbol_syn
PP8997
resolver
genesymbol_syn
TBC1D2A
resolver
hgnc
HGNC:18026
resolver
uniprot
B3KWD1
resolver
uniprot
B4DQ05
resolver
uniprot
B9A6J7
resolver
uniprot
Q59EU0
resolver
uniprot
Q5TBQ5
resolver
uniprot
Q6IPC7
resolver
uniprot
Q7L1K8
resolver
uniprot
Q8WYT1
resolver
uniprot
Q9H6A2
resolver
uniprot
Q9NSH4
resolver
uniprot_entry
TBD2A_HUMAN
resolver
uniprot_sec
B3KWD1
resolver
uniprot_sec
B4DQ05
resolver
uniprot_sec
B9A6J7
resolver
uniprot_sec
Q59EU0
resolver
uniprot_sec
Q5TBQ5
resolver
uniprot_sec
Q6IPC7
resolver
uniprot_sec
Q7L1K8
resolver
uniprot_sec
Q8WYT1
resolver
uniprot_sec
Q9H6A2
resolver
uniprot_sec
Q9NSH4
resolver
amino_acid_sequence
MEGAGENAPESSSSAPGSEESARDPQVPPPEEESGDCARSLEAVPKKLCGYLSKFGGKGPIRGWKSRWFFYDERKCQLYYSRTAQDANPLDSIDLSSAVFDCKADAEEGIFEIKTPSRVITLKAATKQAMLYWLQQLQMKRWEFHNSPPAPPATPDAALAGNGPVLHLELGQEEAELEEFLCPVKTPPGLVGVAAALQPFPALQNISLKHLGTEIQNTMHNIRGNKQAQGTGHEPPGEDSPQSGEPQREEQPLASDASTPGREPEDSPKPAPKPSLTISFAQKAKRQNNTFPFFSEGITRNRTAQEKVAALEQQVLMLTKELKSQKELVKILHKALEAAQQEKRASSAYLAAAEDKDRLELVRHKVRQIAELGRRVEALEQERESLAHTASLREQQVQELQQHVQLLMDKNHAKQQVICKLSEKVTQDFTHPPDQSPLRPDAANRDFLSQQGKIEHLKDDMEAYRTQNCFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEALGDEASECSELLRQLVQEALQWEAGEASSDSIELSPISKYDEYGFLTVPDYEVEDLKLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSAELKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASRRRAVSEGCASEDEVEGEA
uniprot
proteins
function
FUNCTION: Acts as a GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion. {ECO:0000269|PubMed:20116244}.
uniprot
proteins
mass_dalton
105414
uniprot
proteins
pubmed
11785977
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19077034
uniprot
proteins
pubmed
20116244
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
sequence_length
928
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20116244}. Cytoplasmic vesicle {ECO:0000269|PubMed:20116244}. Cell junction {ECO:0000269|PubMed:20116244}.
uniprot
proteins