Mmp19
entrez
58223
canonical
uniprot
Q9JHI0
canonical
ensembl
ENSMUSG00000025355
resolver
ensp
ENSMUSP00000026411
resolver
ensp
ENSMUSP00000151437
resolver
enst
ENSMUST00000026411
resolver
enst
ENSMUST00000219404
resolver
genesymbol
Mmp19
resolver
genesymbol_syn
Rasi
resolver
uniprot
A0A1W2P6X6
resolver
uniprot
Q2KHP2
resolver
uniprot
Q3UW97
resolver
uniprot
Q8C360
resolver
uniprot_entry
A0A1W2P6X6_MOUSE
resolver
uniprot_entry
MMP19_MOUSE
resolver
uniprot_entry
Q2KHP2_MOUSE
resolver
uniprot_entry
Q3UW97_MOUSE
resolver
uniprot_sec
Q8C360
resolver
amino_acid_sequence
MDWQQLWLAFLLPMTVSGRALGPTEKEAVLDYLLQYGYLQKPLEGADDFRLEDITEALRTFQEASGLPISGQMDDATRARMKQPRCGLEDPFNQKSLKYLLLGHWRKKNLTFRIFNVPSTLSLPRVRAALHQAFKYWSSVAPLTFREVKAGWADIRLSFHGRQSLYCSNTFDGPGKVLAHADIPELGSIHFDKDELWTEGTYQGVNLRIIAAHEVGHALGLGHSRYTQALMAPVYAGYQPFFKLHPDDVAGIQALYGKRSPETRDEEEETEMLTVSPVTAKPGPMPNPCSGEVDAMVLGPRGKTYAFKGDYVWTVTDSGPGPLFQISALWEGLPGNLDAAVYSPRTRRTHFFKGNKVWRYVDFKMSPGFPMKFNRVEPNLDAALYWPVNQKVFLFKGSGYWQWDELARTDLSRYPKPIKELFTGVPDRPSAAMSWQDGQVYFFKGKEYWRLNQQLRVAKGYPRNTTHWMHCGSQTPDTNSSTGDVTPSTTDTVLGTTPSTMGSTLDIPSATDSASLSFSANVTLLGA
uniprot
proteins
ec_number
3.4.24.-
uniprot
proteins
function
FUNCTION: Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis (By similarity). Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
59122
uniprot
proteins
post_translational_modification
PTM: Activated by autolytic cleavage after Lys-98. {ECO:0000250}.; PTM: Tyrosine phosphorylated by PKDCC/VLK. {ECO:0000250|UniProtKB:Q99542}.
uniprot
proteins
protein_family
Peptidase M10A family
uniprot
proteins
pubmed
11054540
uniprot
proteins
pubmed
11092553
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
527
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}; Extracellular side {ECO:0000305}. Secreted, extracellular space, extracellular matrix {ECO:0000305}.
uniprot
proteins