Tmtc1
entrez
387314
canonical
uniprot
Q3UV71
canonical
ensembl
ENSMUSG00000030306
resolver
ensp
ENSMUSP00000056353
resolver
ensp
ENSMUSP00000098335
resolver
ensp
ENSMUSP00000220446
resolver
ensp
ENSMUSP00000220448
resolver
genesymbol
Tmtc1
resolver
uniprot
E9QM13
resolver
uniprot
Q8BQV5
resolver
uniprot_entry
TMTC1_MOUSE
resolver
uniprot_sec
E9QM13
resolver
uniprot_sec
Q8BQV5
resolver
amino_acid_sequence
MLVTRGDRGGGERAPSRRPRCGLVPAGAAALLAGASCLCYGRSLRGEFVHDDVWAIVNNPDVRPGTPLRWAIFANDFWGKGLADSTSHKSYRPLCVLSFRLNIFLTGMNPFYFHAVNVILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPVHTEAVAGIVGRADVLACLLFLLAFLSYQRSLDQGCAGQCFPTTASPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSPSHKQDKLSNGAVCQHSSGQPGSPQPSSQQAHPHRESRKQRFPHKDSWGGCHSPLPPEPKSSGFPMSPRAMWSLMRCLTGSTNRNFLLTLRPFLKRAILVISYVTVILYFRLWIMGGTMPLFSEQDNPASFSPYILTRFLTYSYLLAFNVWLLLAPITLCYDWQVGSIPLVETIWDVRNLATILLAVVMALLSLHCVAAFKRLEHKEVLAGLLFLVFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLSKLCAGLSRCGATSLMASTVLLLLLFSWKTVKQNEIWLSRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQERFKEAEDIYQAGIKNCPDSSDLHNNYAVFLVDSGFPEKAVAHYQQAIQLSPSHHVAVVNLGRLYRSLGENSKAEEWYRRALKVARTAEVLSPLGALYYNTGRHKEALEVYREAVSLQPSQRELRLALAQVLAVMGQTKEAEKITSHIVSEEPRCLECYRLLSAIHSKQEHHGKALEAIEKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYEAAVTLDPDQAQAWMNMGGIRHIQGSYVSARAYYERALKLVPDSKLLKENLAKLDRLERRLQEVRERDQT
uniprot
proteins
ec_number
2.4.1.109
uniprot
proteins
function
FUNCTION: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. {ECO:0000250|UniProtKB:Q8IUR5}.
uniprot
proteins
mass_dalton
105811
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q8IUR5}.
uniprot
proteins
protein_family
TMTC family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
942
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8IUR5}.
uniprot
proteins
transmembrane_region
TRANSMEM 21..41; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 110..130; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 141..157; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 160..180; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 197..217; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 332..352; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 374..394; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 415..435; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 442..462; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 464..484; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 499..519; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins