Ppm1b
entrez
24667
canonical
uniprot
P35815
canonical
ensembl
ENSRNOG00000030667
resolver
ensembl
ENSRNOG00055022700
resolver
ensembl
ENSRNOG00060004300
resolver
ensembl
ENSRNOG00065007932
resolver
ensp
ENSRNOP00000099191
resolver
ensp
ENSRNOP00000102147
resolver
ensp
ENSRNOP00000109449
resolver
enst
ENSRNOT00000154745
resolver
enst
ENSRNOT00000167508
resolver
genesymbol
Ppm1b
resolver
genesymbol_syn
Pp2c2
resolver
genesymbol_syn
Pppm1b
resolver
genesymbol_syn
ppm1b2
resolver
uniprot
A0ABK0L5V2
resolver
uniprot
A0ABK0LFW6
resolver
uniprot
A6H9I0
resolver
uniprot
D3ZLY2
resolver
uniprot
Q546R0
resolver
uniprot
Q64046
resolver
uniprot
Q642F2
resolver
uniprot
Q99ND8
resolver
uniprot_entry
A0ABK0L5V2_RAT
resolver
uniprot_entry
A0ABK0LFW6_RAT
resolver
uniprot_entry
A6H9I0_RAT
resolver
uniprot_entry
PPM1B_RAT
resolver
uniprot_entry
Q642F2_RAT
resolver
uniprot_sec
D3ZLY2
resolver
uniprot_sec
Q546R0
resolver
uniprot_sec
Q64046
resolver
uniprot_sec
Q99ND8
resolver
amino_acid_sequence
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGFALEPSVENVKTGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPTHIYFINCGDSRAVLCRNGQVCFSTQDHKPCNPMEKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFVVLACDGIWDVMSNEELCEFVNSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFANAPKVSDEAVKRDLELDKHLESRVEEIMQKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPNKDNDGGAGDLEDSLVAL
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Enzyme with a broad specificity. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
42889
uniprot
proteins
post_translational_modification
PTM: Isgylation negatively regulates its activity. {ECO:0000250}.; PTM: N-myristoylation is essential for the recognition of its substrates for dephosphorylation. {ECO:0000250}.
uniprot
proteins
protein_family
PP2C family
uniprot
proteins
pubmed
1312947
uniprot
proteins
pubmed
7532404
uniprot
proteins
sequence_length
390
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P36993}. Membrane {ECO:0000250|UniProtKB:P36993}; Lipid-anchor {ECO:0000250|UniProtKB:P36993}. Note=Weakly associates at the membrane and N-myristoylation mediates the membrane localization. {ECO:0000250|UniProtKB:P36993}.
uniprot
proteins