FGF19
entrez
9965
canonical
uniprot
O95750
canonical
ensembl
ENSG00000162344
resolver
ensp
ENSP00000294312
resolver
ensp
ENSP00000581962
resolver
enst
ENST00000294312
resolver
enst
ENST00000911903
resolver
genesymbol
FGF19
resolver
hgnc
HGNC:3675
resolver
uniprot_entry
FGF19_HUMAN
resolver
amino_acid_sequence
MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
uniprot
proteins
function
FUNCTION: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. {ECO:0000269|PubMed:12815072, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:17623664, ECO:0000269|PubMed:19085950}.
uniprot
proteins
mass_dalton
24003
uniprot
proteins
protein_family
Heparin-binding growth factors family
uniprot
proteins
pubmed
10525310
uniprot
proteins
pubmed
12815072
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14730967
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16597617
uniprot
proteins
pubmed
17339340
uniprot
proteins
pubmed
17623664
uniprot
proteins
pubmed
18829467
uniprot
proteins
pubmed
19085950
uniprot
proteins
pubmed
20094046
uniprot
proteins
pubmed
23747249
uniprot
proteins
pubmed
9931477
uniprot
proteins
sequence_length
216
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins