Fabp4
entrez
11770
canonical
uniprot
P04117
canonical
ensembl
ENSMUSG00000062515
resolver
ensp
ENSMUSP00000029041
resolver
ensp
ENSMUSP00000245943
resolver
ensp
ENSMUSP00000245949
resolver
enst
ENSMUST00000029041
resolver
genesymbol
Fabp4
resolver
genesymbol_syn
Ap2
resolver
uniprot
Q542H7
resolver
uniprot_entry
FABP4_MOUSE
resolver
uniprot_entry
Q542H7_MOUSE
resolver
amino_acid_sequence
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDLVTIRSESTFKNTEISFKLGVEFDEITADDRKVKSIITLDGGALVQVQKWDGKSTTIKRKRDGDKLVVECVMKGVTSTRVYERA
uniprot
proteins
function
FUNCTION: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. {ECO:0000269|PubMed:12077340, ECO:0000269|PubMed:16574478, ECO:0000269|PubMed:17516629}.
uniprot
proteins
mass_dalton
14650
uniprot
proteins
mutagenesis
MUTAGEN 22; /note="K->A: Abolishes ligand-induced translocation to the nucleus; when associated with A-31 and A-32."; /evidence="ECO:0000269|PubMed:17516629"; MUTAGEN 31; /note="R->A: Abolishes ligand-induced translocation to the nucleus; when associated with A-22 and A-32."; /evidence="ECO:0000269|PubMed:17516629"; MUTAGEN 32; /note="K->A: Abolishes ligand-induced translocation to the nucleus; when associated with A-22 and A-31."; /evidence="ECO:0000269|PubMed:17516629"; MUTAGEN 58; /note="F->A: Abolishes ligand-induced translocation to the nucleus."; /evidence="ECO:0000269|PubMed:17761196"; MUTAGEN 67; /note="L->A: Abolishes export from nucleus; when associated with A-87 and A-92."; /evidence="ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196"; MUTAGEN 87; /note="L->A: Abolishes export from nucleus; when associated with A-67 and A-92."; /evidence="ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196"; MUTAGEN 92; /note="L->A: Abolishes export from nucleus; when associated with A-67 and A-87."; /evidence="ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196
uniprot
proteins
protein_family
Calycin superfamily
uniprot
proteins
protein_family
Fatty-acid binding protein (FABP) family
uniprot
proteins
pubmed
10423455
uniprot
proteins
pubmed
12077340
uniprot
proteins
pubmed
14594993
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1554730
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16574478
uniprot
proteins
pubmed
17516629
uniprot
proteins
pubmed
17761196
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2452440
uniprot
proteins
pubmed
2844775
uniprot
proteins
pubmed
3015943
uniprot
proteins
pubmed
3520554
uniprot
proteins
pubmed
3968175
uniprot
proteins
pubmed
6206497
uniprot
proteins
pubmed
7929228
uniprot
proteins
pubmed
8161548
uniprot
proteins
pubmed
8447836
uniprot
proteins
pubmed
8463311
uniprot
proteins
sequence_length
132
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196}. Nucleus {ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196}. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus (PubMed:17516629). Subject to constitutive nuclear export (PubMed:17516629, PubMed:17761196). {ECO:0000269|PubMed:17516629, ECO:0000269|PubMed:17761196}.
uniprot
proteins