DFFA
entrez
1676
canonical
uniprot
O00273
canonical
ensembl
ENSG00000160049
resolver
ensp
ENSP00000366235
resolver
ensp
ENSP00000366237
resolver
genesymbol
DFFA
resolver
genesymbol_syn
DFF1
resolver
genesymbol_syn
DFF45
resolver
hgnc
HGNC:2772
resolver
uniprot
Q5T6G5
resolver
uniprot
Q5T6G6
resolver
uniprot
Q96I97
resolver
uniprot
Q9Y6C6
resolver
uniprot_entry
DFFA_HUMAN
resolver
uniprot_sec
Q5T6G5
resolver
uniprot_sec
Q5T6G6
resolver
uniprot_sec
Q96I97
resolver
uniprot_sec
Q9Y6C6
resolver
amino_acid_sequence
MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDLQNPKRARQDPT
uniprot
proteins
function
FUNCTION: Inhibitor of the caspase-activated DNase (DFF40).
uniprot
proteins
mass_dalton
36522
uniprot
proteins
post_translational_modification
PTM: Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
uniprot
proteins
pubmed
10409614
uniprot
proteins
pubmed
10497265
uniprot
proteins
pubmed
11371636
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9108473
uniprot
proteins
sequence_length
331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins