Siva1
entrez
30954
canonical
uniprot
O54926
canonical
ensembl
ENSMUSG00000064326
resolver
ensp
ENSMUSP00000021728
resolver
ensp
ENSMUSP00000105377
resolver
genesymbol
Siva1
resolver
genesymbol_syn
Siva
resolver
uniprot
Q3U6J2
resolver
uniprot
Q921I8
resolver
uniprot
Q9CWL1
resolver
uniprot
Q9R1Q0
resolver
uniprot
Q9R1Q1
resolver
uniprot_entry
SIVA_MOUSE
resolver
uniprot_sec
Q3U6J2
resolver
uniprot_sec
Q921I8
resolver
uniprot_sec
Q9CWL1
resolver
uniprot_sec
Q9R1Q0
resolver
uniprot_sec
Q9R1Q1
resolver
amino_acid_sequence
MPKRSCPFADAAPLQLKVHVGLKELSHGVFAERYSREVFERTKQLLFQGARAYRDHISSEDCSVNHLQESLKSGVVGAPQPARGQMLIGPDGRLTRCQAQASEGGLPRTAPIACSSCMRSVDGKAVCSQCERALCGQCVYTCWGCGALACVLCGLADYADDGEKTLCTSCAMFEA
uniprot
proteins
function
FUNCTION: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis (By similarity). {ECO:0000250, ECO:0000269|PubMed:9177220}.
uniprot
proteins
mass_dalton
18770
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by ABL2/ARG in response to oxidative stress. {ECO:0000250}.
uniprot
proteins
pubmed
10597319
uniprot
proteins
pubmed
10756043
uniprot
proteins
pubmed
12478477
uniprot
proteins
pubmed
15105421
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
9177220
uniprot
proteins
sequence_length
175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus {ECO:0000250}. Note=In the nucleus, accumulates in dot-like structures. {ECO:0000250}.
uniprot
proteins