PRSS2
entrez
5645
canonical
uniprot
P07478
canonical
ensembl
ENSG00000275896
resolver
ensembl
ENSG00000282049
resolver
ensp
ENSP00000487952
resolver
ensp
ENSP00000488338
resolver
ensp
ENSP00000488437
resolver
ensp
ENSP00000488789
resolver
enst
ENST00000539842
resolver
enst
ENST00000632112
resolver
enst
ENST00000632998
resolver
enst
ENST00000633969
resolver
genesymbol
PRSS2
resolver
genesymbol_syn
TRY2
resolver
genesymbol_syn
TRYP2
resolver
hgnc
HGNC:9483
resolver
uniprot
A0A0J9YXK0
resolver
uniprot
A0A0J9YYC8
resolver
uniprot
A6XMV9
resolver
uniprot
Q5NV56
resolver
uniprot
Q6PK75
resolver
uniprot_entry
A0A0J9YXK0_HUMAN
resolver
uniprot_entry
A0A0J9YYC8_HUMAN
resolver
uniprot_entry
A6XMV9_HUMAN
resolver
uniprot_entry
Q5NV56_HUMAN
resolver
uniprot_entry
Q6PK75_HUMAN
resolver
uniprot_entry
TRY2_HUMAN
resolver
amino_acid_sequence
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTIAANS
uniprot
proteins
ec_number
3.4.21.4
uniprot
proteins
function
FUNCTION: In the ileum, may be involved in defensin processing, including DEFA5. {ECO:0000269|PubMed:12021776}.
uniprot
proteins
mass_dalton
26488
uniprot
proteins
post_translational_modification
PTM: Sulfated on tyrosine. {ECO:0000269|PubMed:17087724}.; PTM: Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins. {ECO:0000269|PubMed:25010489}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
12021776
uniprot
proteins
pubmed
17087724
uniprot
proteins
pubmed
18986305
uniprot
proteins
pubmed
25010489
uniprot
proteins
pubmed
2598466
uniprot
proteins
pubmed
3011602
uniprot
proteins
sequence_length
247
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space.
uniprot
proteins