Nudt8
entrez
66387
canonical
uniprot
Q9CR24
canonical
ensembl
ENSMUSG00000024869
resolver
ensembl
ENSMUSG00000110949
resolver
ensp
ENSMUSP00000025802
resolver
ensp
ENSMUSP00000119218
resolver
enst
ENSMUST00000025802
resolver
enst
ENSMUST00000155405
resolver
genesymbol
Nudt8
resolver
uniprot
Q3TDQ2
resolver
uniprot_entry
NUDT8_MOUSE
resolver
uniprot_sec
Q3TDQ2
resolver
amino_acid_sequence
MLPDGLSAEDEQRCRQLLARTTARLRSRPAAAAVLVPLCLVRGVPALLYTLRSSRLVGRHKGEVSFPGGKCDPDDQDVIHTALRETQEELGLEVPKEHVWGVLQPVYDREKATIVPVLANVGPLDLQSLRPNLEEVDEVFEMSLAHLLQTQNQGYTHFCQGGHFSYTLPVFLHGPHRVWGLTAVITELTLKLLAPGFYQPSLAVPELPRG
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
ec_number
3.6.1.77
uniprot
proteins
function
FUNCTION: Acyl-CoA diphosphatase that mediates the hydrolysis of a wide range of CoA and CoA esters yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products (PubMed:31004344). Hydrolyzes short- and medium-chain acyl-CoAs, exhibiting the highest activity toward free CoA, hexanoyl-CoA, and octanoyl-CoA and the lowest activity against acetyl-CoA (PubMed:31004344). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (PubMed:32432673). {ECO:0000269|PubMed:31004344, ECO:0000269|PubMed:32432673}.
uniprot
proteins
mass_dalton
23253
uniprot
proteins
protein_family
Nudix hydrolase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
31004344
uniprot
proteins
pubmed
32432673
uniprot
proteins
sequence_length
210
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:31004344}.
uniprot
proteins