Tent5a
entrez
212943
canonical
uniprot
D3Z5S8
canonical
ensembl
ENSMUSG00000032265
resolver
ensp
ENSMUSP00000034802
resolver
ensp
ENSMUSP00000140869
resolver
enst
ENSMUST00000034802
resolver
enst
ENSMUST00000187711
resolver
genesymbol
Tent5a
resolver
genesymbol_syn
Fam46a
resolver
uniprot
A0A087WS27
resolver
uniprot_entry
A0A087WS27_MOUSE
resolver
uniprot_entry
TET5A_MOUSE
resolver
amino_acid_sequence
MHQRYFWTDQGQVAFGGHYMAEGEGYFAMAEDELTGGPYIPLGGDFGGGGSSFGDRCSDYCESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLEEKGIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEEEFQTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKNVELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSENPMTETFHPTIIGESVYGDFHEAFDHLCNKIIATRNPEEIRGGGLLKYCNLLVRGFRPASEEIKTLQRYMCSRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYDYLMTLHGVVNESTVCLMGHERRQTLNLITMLAIRVLADQNVIPNVANVTCYYQPAPYVADANFSNYYIAQVQPVFTCQQQTYSTWLPCN
uniprot
proteins
ec_number
2.7.7.19
uniprot
proteins
function
FUNCTION: Cytoplasmic non-canonical poly(A) RNA polymerase that catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and participates in the cytoplasmic polyadenylation (PubMed:33882302). Polyadenylates mRNA encoding extracellular matrix constituents and other genes crucial for bone mineralization and during osteoblast mineralization, mainly focuses on ER-targeted mRNAs (PubMed:26803617, PubMed:33882302). {ECO:0000269|PubMed:26803617, ECO:0000269|PubMed:33882302}.
uniprot
proteins
mass_dalton
50793
uniprot
proteins
mutagenesis
MUTAGEN 157..447; /note="Missing: Homozygous mice show severe morphological and skeletal abnormalities including short stature along with limb, rib, pelvis, and skull deformities with minimal trabecular bone and reduced cortical bone thickness in long bones."; /evidence="ECO:0000269|PubMed:26803617
uniprot
proteins
protein_family
TENT family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19740458
uniprot
proteins
pubmed
26803617
uniprot
proteins
pubmed
33882302
uniprot
proteins
sequence_length
447
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:33882302}.
uniprot
proteins