Cyb561d2
entrez
56368
canonical
uniprot
Q9WUE3
canonical
ensembl
ENSMUSG00000037190
resolver
ensp
ENSMUSP00000044093
resolver
ensp
ENSMUSP00000141723
resolver
enst
ENSMUST00000041459
resolver
enst
ENSMUST00000195235
resolver
genesymbol
Cyb561d2
resolver
genesymbol_syn
101f6
resolver
uniprot
Q3TRQ1
resolver
uniprot_entry
C56D2_MOUSE
resolver
uniprot_sec
Q3TRQ1
resolver
amino_acid_sequence
MALSVETESHIYRALRTASGAAAHLVALGFTIFVAVLARPGSSLFSWHPVLMSLAFSFLMTEALLMFSPESSLLRSLSRKVRARCHWVLQLLALLCALLGLGLVILHKEQLGKAHLTTRHGQAGLLAVLWAGLQCSGGMGLLYPKLLPRWPLAKLKLYHATSGLVGYLLGSASLLLGMFSLWFTATVTGGAWYLAVLCPILTSLVIMNQVSNAYLYRKRIQP
uniprot
proteins
ec_number
7.2.1.3
uniprot
proteins
function
FUNCTION: Transmembrane reductase that may use ascorbate as an electron donor in the cytoplasm and transfer electrons across endoplasmic reticulum membranes to reduce monodehydro-L-ascorbate radical and iron cations Fe(3+) in the lumen of that compartment. {ECO:0000269|PubMed:17938141, ECO:0000269|PubMed:19943161}.
uniprot
proteins
mass_dalton
24187
uniprot
proteins
mutagenesis
MUTAGEN 111..222; /note="Missing: Loss of heme binding."; /evidence="ECO:0000269|PubMed:17938141"; MUTAGEN 139..222; /note="Missing: Loss of heme binding."; /evidence="ECO:0000269|PubMed:17938141
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17938141
uniprot
proteins
pubmed
19943161
uniprot
proteins
sequence_length
222
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:17938141}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:17938141}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 47..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 123..143; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 163..183; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 187..207; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins