Hsd3b3
entrez
15494
canonical
uniprot
P26150
canonical
ensembl
ENSMUSG00000062410
resolver
ensp
ENSMUSP00000088246
resolver
ensp
ENSMUSP00000091592
resolver
ensp
ENSMUSP00000102632
resolver
ensp
ENSMUSP00000102633
resolver
ensp
ENSMUSP00000278340
resolver
ensp
ENSMUSP00000278341
resolver
ensp
ENSMUSP00000362440
resolver
enst
ENSMUST00000090743
resolver
enst
ENSMUST00000094050
resolver
enst
ENSMUST00000107018
resolver
enst
ENSMUST00000107019
resolver
genesymbol
Hsd3b3
resolver
uniprot
E9PXG7
resolver
uniprot_entry
3BHS3_MOUSE
resolver
uniprot_entry
E9PXG7_MOUSE
resolver
amino_acid_sequence
MPGWSCLVTGAGGFLGQRIIQLLVQEKDLEEIRVLDKVFKPETREQFFNLGTSIKVTVLEGDILDTQYLRRACQGISVVIHTAAIIDVTGVIPRQTILDVNLKGTQNLLEACIQASVPAFIFSSSVDVAGPNSYKDIVLNGHEDEHRESTWSDPYPYSKKMAEKAVLAANGSMLKNGGTLQTCALRPMCIYGERSQFLSNTIIKALKNKFILRGGGKFSTANPVYVGNVAWAHILAARGLRNPKKSPNIQGEFYYISDDTPHQSYDDLNYTLSKEWGFCLNSRWYLPVPILYWLAFLLETVSFLLSPIYRYIPPFNRHLVTLTASTFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
uniprot
proteins
ec_number
1.1.1.145
uniprot
proteins
ec_number
5.3.3.1
uniprot
proteins
function
FUNCTION: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
uniprot
proteins
mass_dalton
42031
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; steroid biosynthesis.
uniprot
proteins
protein_family
3-beta-HSD family
uniprot
proteins
pubmed
1924345
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins