Grwd1
entrez
308592
canonical
uniprot
Q5XI13
canonical
ensembl
ENSRNOG00000021058
resolver
ensp
ENSRNOP00000053027
resolver
genesymbol
Grwd1
resolver
uniprot_entry
GRWD1_RAT
resolver
amino_acid_sequence
MAARKGRRHTCETGEPMEAETYDLGSEGPSQVYLPGRGPPLGEGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLSLYLCAGTQAESAQSNRLMMLRMHNLHGTRPPPSEGSDDEDDEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFALRRLLQVVDDPQALAIFLRDEQARVKPIFSFAGHMGEGFALDWSPRVPGRLLTGDCQKNIHLWTPTDGGSWNVDQRPFVGHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLLSGGDDGTLKVWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDPESGETETDPGLAALPQQLLFVHQGETDLKELHWHPQCPGVLISTALSGFTVFRTISV
uniprot
proteins
function
FUNCTION: Histone binding protein that regulates chromatin dynamics and loading of minichromosome maintenance (MCM) complex at replication origins, possibly by promoting chromatin openness. Plays a role in ribosomal biogenesis. {ECO:0000250|UniProtKB:Q9BQ67}.
uniprot
proteins
mass_dalton
49169
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
445
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9BQ67}. Nucleus {ECO:0000250|UniProtKB:Q9BQ67}. Chromosome {ECO:0000250|UniProtKB:Q9BQ67}. Note=Present in the nucleus throughout interphase and is detached from chromatin at the onset of mitosis and rebinds at telophase when the pre-replication complexes (pre-RC) is formed. {ECO:0000250|UniProtKB:Q9BQ67}.
uniprot
proteins