HLA-DOA
entrez
3111
canonical
uniprot
P06340
canonical
ensembl
ENSG00000204252
resolver
ensembl
ENSG00000206292
resolver
ensembl
ENSG00000230141
resolver
ensembl
ENSG00000231558
resolver
ensembl
ENSG00000232957
resolver
ensembl
ENSG00000232962
resolver
ensembl
ENSG00000235744
resolver
ensp
ENSP00000229829
resolver
ensp
ENSP00000372713
resolver
ensp
ENSP00000395737
resolver
ensp
ENSP00000397945
resolver
ensp
ENSP00000398819
resolver
ensp
ENSP00000401504
resolver
ensp
ENSP00000416448
resolver
enst
ENST00000229829
resolver
enst
ENST00000383226
resolver
enst
ENST00000426070
resolver
enst
ENST00000426685
resolver
enst
ENST00000434335
resolver
enst
ENST00000438987
resolver
enst
ENST00000452598
resolver
genesymbol
HLA-DOA
resolver
genesymbol_syn
HLA-DNA
resolver
genesymbol_syn
HLA-DZA
resolver
hgnc
HGNC:4936
resolver
uniprot
Q58HU0
resolver
uniprot
Q58HU1
resolver
uniprot
Q5STC7
resolver
uniprot
Q9TQC6
resolver
uniprot
Q9TQC7
resolver
uniprot
Q9TQC8
resolver
uniprot
Q9TQC9
resolver
uniprot
Q9TQD0
resolver
uniprot
Q9TQD1
resolver
uniprot
Q9TQD2
resolver
uniprot
Q9TQD3
resolver
uniprot_entry
DOA_HUMAN
resolver
uniprot_sec
Q58HU0
resolver
uniprot_sec
Q58HU1
resolver
uniprot_sec
Q5STC7
resolver
uniprot_sec
Q9TQC6
resolver
uniprot_sec
Q9TQC7
resolver
uniprot_sec
Q9TQC8
resolver
uniprot_sec
Q9TQC9
resolver
uniprot_sec
Q9TQD0
resolver
uniprot_sec
Q9TQD1
resolver
uniprot_sec
Q9TQD2
resolver
uniprot_sec
Q9TQD3
resolver
amino_acid_sequence
MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFVPSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR
uniprot
proteins
function
FUNCTION: Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
uniprot
proteins
mass_dalton
27599
uniprot
proteins
protein_family
MHC class II family
uniprot
proteins
pubmed
10323340
uniprot
proteins
pubmed
10837054
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16101837
uniprot
proteins
pubmed
2370084
uniprot
proteins
pubmed
2499532
uniprot
proteins
pubmed
3000765
uniprot
proteins
sequence_length
250
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
uniprot
proteins
transmembrane_region
TRANSMEM 218..240; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins