Nr0b1
entrez
11614
canonical
uniprot
Q61066
canonical
ensembl
ENSMUSG00000025056
resolver
ensp
ENSMUSP00000026036
resolver
enst
ENSMUST00000026036
resolver
genesymbol
Nr0b1
resolver
genesymbol_syn
Ahch
resolver
genesymbol_syn
Dax1
resolver
uniprot
O09068
resolver
uniprot
O09147
resolver
uniprot
Q53ZY9
resolver
uniprot_entry
NR0B1_MOUSE
resolver
uniprot_entry
Q53ZY9_MOUSE
resolver
uniprot_sec
O09068
resolver
uniprot_sec
O09147
resolver
amino_acid_sequence
MAGEDHPWQGSILYNLLMSAKQKHASQEEREVRLGAQCWGCACGAQPVLGGERLSGGQARSLLYRCCFCGENHPRQGGILYSMLTNARQPSVATQAPRARFGAPCWGCACGSAEPLVGREGLPAGQAPSLLYRCCFCGEEHPRQGSILYSLLTSAQQTHVSREAPEAHRRGEWWQLSYCTQSVGGPEGLQSTQAMAFLYRSYVCGEEQPQQISVASGTPVSADQTPATPQEQPRAPWWDASPGVQRLITLKDPQVVCEAASAGLLKTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLELAQDHLHFEMMEIPETNTTQEMLTTRRQETEGPEPAEPQATEQPQMVSAEAGHLLPAAAVQAIKSFFFKCWSLNIDTKEYAYLKGTVLFNPDLPGLQCVKYIEGLQWRTQQILTEHIRMMQREYQIRSAELNSALFLLRFINSDVVTELFFRPIIGAVSMDDMMLEMLCAKL
uniprot
proteins
function
FUNCTION: Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions (PubMed:19015525). Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis (By similarity). May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (PubMed:16466956). {ECO:0000250|UniProtKB:P51843, ECO:0000269|PubMed:16466956, ECO:0000269|PubMed:19015525}.
uniprot
proteins
mass_dalton
52576
uniprot
proteins
protein_family
NR0 subfamily
uniprot
proteins
protein_family
Nuclear hormone receptor family
uniprot
proteins
pubmed
16466956
uniprot
proteins
pubmed
19015525
uniprot
proteins
pubmed
27601327
uniprot
proteins
pubmed
8756567
uniprot
proteins
pubmed
8921887
uniprot
proteins
sequence_length
472
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P51843}. Cytoplasm {ECO:0000250|UniProtKB:P51843}. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus. {ECO:0000250|UniProtKB:P51843}.
uniprot
proteins