Tmem214
entrez
362711
canonical
uniprot
A1L1L2
canonical
ensembl
ENSRNOG00000008812
resolver
ensembl
ENSRNOG00055020006
resolver
ensembl
ENSRNOG00060011658
resolver
ensembl
ENSRNOG00065023772
resolver
ensp
ENSRNOP00000011838
resolver
ensp
ENSRNOP00055027713
resolver
ensp
ENSRNOP00060015533
resolver
ensp
ENSRNOP00065033239
resolver
enst
ENSRNOT00000011838
resolver
enst
ENSRNOT00055034166
resolver
enst
ENSRNOT00060019741
resolver
enst
ENSRNOT00065040750
resolver
genesymbol
Tmem214
resolver
uniprot
Q5U4F5
resolver
uniprot_entry
TM214_RAT
resolver
uniprot_sec
Q5U4F5
resolver
amino_acid_sequence
MAARAAGSGGWEVVKRSRRPGASSGGRGGGGDRRALGEANGVWKYDLSSPIQPTSTLYERGFEKIMKRQNKEQVPPPAAESKKPVNKKQPKKVTAVASQNQKQGPFRSLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMYPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLTSWEQIPKKARKCLQETIQSFTLTNQELLKKGSGSNEHVVTCDTACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLQSSGLLPVAQQVCAKLYSYSLQSYNWLQETLPACGSYLLAVVQPSLQLAWTYIYATFSFLSAYCASYLAFFSDSLAGVLQRVQLPEALHQLFHSLKELLLLFYHSVLLPMWHLLLAALAQVQEHCHEACRGEMTWDCIKTQFSTAAHWTWLCLQDVTVAFLDWALTMISQQ
uniprot
proteins
function
FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
76566
uniprot
proteins
protein_family
TMEM214 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
685
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 479..499; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 612..632; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins