Kctd1
entrez
291772
canonical
uniprot
Q8R4G8
canonical
ensembl
ENSRNOG00000016467
resolver
ensp
ENSRNOP00000109347
resolver
enst
ENSRNOT00000171210
resolver
genesymbol
Kctd1
resolver
genesymbol_syn
Vad6
resolver
uniprot
A0ABK0M2H2
resolver
uniprot_entry
A0ABK0M2H2_RAT
resolver
uniprot_entry
KCTD1_RAT
resolver
amino_acid_sequence
MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETSRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELRRTPRVPSVIRIKQEPLD
uniprot
proteins
function
FUNCTION: Is a regulator of different signaling pathways. Up-regulates ADCY5 thereby enhancing cAMP signaling, and is involved in the negative regulation of Wnt canonical, Hh and Notch signaling (By similarity). Is a repressor of transcriptional activation mediated by AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent (By similarity). {ECO:0000250|UniProtKB:Q719H9}.
uniprot
proteins
mass_dalton
29435
uniprot
proteins
post_translational_modification
PTM: Sumoylated. {ECO:0000250}.
uniprot
proteins
pubmed
12878178
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
257
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q719H9}.
uniprot
proteins