SYP
entrez
6855
canonical
uniprot
P08247
canonical
ensembl
ENSG00000102003
resolver
ensp
ENSP00000263233
resolver
genesymbol
SYP
resolver
hgnc
HGNC:11506
resolver
uniprot
B2R7L6
resolver
uniprot
B7Z359
resolver
uniprot
Q6P2F7
resolver
uniprot_entry
SYPH_HUMAN
resolver
uniprot_sec
B2R7L6
resolver
uniprot_sec
B7Z359
resolver
uniprot_sec
Q6P2F7
resolver
amino_acid_sequence
MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLSIEVEFEYPFRLHQVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGDYGQQGYGPQGAPTSFSNQM
uniprot
proteins
disease_involvement
DISEASE: Intellectual developmental disorder, X-linked 96 (XLID96) [MIM:300802]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. {ECO:0000269|PubMed:19377476}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33845
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. {ECO:0000250}.; PTM: Phosphorylated by SRC. {ECO:0000250|UniProtKB:P07825}.
uniprot
proteins
protein_family
Synaptophysin/synaptobrevin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
17296554
uniprot
proteins
pubmed
18662323
uniprot
proteins
pubmed
19377476
uniprot
proteins
pubmed
1975480
uniprot
proteins
pubmed
28669405
uniprot
proteins
pubmed
3120152
uniprot
proteins
pubmed
8838578
uniprot
proteins
pubmed
9344658
uniprot
proteins
sequence_length
313
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:18662323}; Multi-pass membrane protein {ECO:0000255}. Synapse, synaptosome {ECO:0000269|PubMed:18662323}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..49; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 107..130; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 138..161; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 200..223; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins