Kynu
entrez
70789
canonical
uniprot
Q9CXF0
canonical
ensembl
ENSMUSG00000026866
resolver
ensp
ENSMUSP00000028223
resolver
ensp
ENSMUSP00000061775
resolver
ensp
ENSMUSP00000108445
resolver
ensp
ENSMUSP00000159520
resolver
ensp
ENSMUSP00000191870
resolver
ensp
ENSMUSP00000191871
resolver
enst
ENSMUST00000028223
resolver
enst
ENSMUST00000240759
resolver
genesymbol
Kynu
resolver
genesymbol_syn
KYNU
resolver
uniprot
A2ARD6
resolver
uniprot
Q6NSV5
resolver
uniprot_entry
A2ARD6_MOUSE
resolver
uniprot_entry
KYNU_MOUSE
resolver
uniprot_entry
Q6NSV5_MOUSE
resolver
amino_acid_sequence
MEPSPLELPVDAVRRIAAELNCDPTDERVALRLDEEDKLSHFRNCFYIPKMRDLPSIDLSLVSEDDDAIYFLGNSLGLQPKMVRTYLEEELDKWAKMGAYGHDVGKRPWIVGDESIVSLMKDIVGAHEKEIALMNALTINLHLLLLSFFKPTPKRHKILLEAKAFPSDHYAIESQIQLHGLDVEKSMRMVKPREGEETLRMEDILEVIEEEGDSIAVILFSGLHFYTGQLFNIPAITKAGHAKGCFVGFDLAHAVGNVELRLHDWGVDFACWCSYKYLNSGAGGLAGAFVHEKHAHTVKPALVGWFGHDLSTRFNMDNKLQLIPGANGFRISNPPILLVCSLHASLEVFQQATMTALRRKSILLTGYLEYMLKHYHSKDNTENKGPIVNIITPSRAEERGCQLTLTFSIPKKSVFKELEKRGVVCDKREPDGIRVAPVPLYNSFHDVYKFIRLLTSILDSSERS
uniprot
proteins
ec_number
3.7.1.3
uniprot
proteins
function
FUNCTION: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. {ECO:0000255|HAMAP-Rule:MF_03017}.
uniprot
proteins
mass_dalton
52325
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. {ECO:0000255|HAMAP-Rule:MF_03017, ECO:0000269|PubMed:28792876}.; PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3. {ECO:0000255|HAMAP-Rule:MF_03017}.
uniprot
proteins
protein_family
Kynureninase family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28792876
uniprot
proteins
sequence_length
464
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000255|HAMAP-Rule:MF_03017}.
uniprot
proteins