Timm17a
entrez
21854
canonical
uniprot
Q9Z0V8
canonical
ensembl
ENSMUSG00000062580
resolver
ensp
ENSMUSP00000079883
resolver
enst
ENSMUST00000081104
resolver
genesymbol
Timm17a
resolver
genesymbol_syn
Tim17a
resolver
uniprot
Q545U2
resolver
uniprot_entry
Q545U2_MOUSE
resolver
uniprot_entry
TI17A_MOUSE
resolver
amino_acid_sequence
MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAFKGFRNSPVGINHRLRGSLTAIKTRAPQLGGSFAVWGGLFSTIDCSMVQIRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFASAQFPNGPQFTEDHSQLPSSQLPSSPFGDYRQYQ
uniprot
proteins
function
FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. {ECO:0000250|UniProtKB:Q99595}.
uniprot
proteins
mass_dalton
18112
uniprot
proteins
post_translational_modification
PTM: Degraded by YMEL1 downstream of the integrated stress response (ISR). {ECO:0000250|UniProtKB:Q99595}.
uniprot
proteins
protein_family
Tim17/Tim22/Tim23 family
uniprot
proteins
pubmed
10339406
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
171
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q99595}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..37; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 63..77; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 113..133; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins