Kcng2
entrez
307234
canonical
uniprot
Q9QYU3
canonical
ensembl
ENSRNOG00000053640
resolver
ensp
ENSRNOP00000069556
resolver
enst
ENSRNOT00000088054
resolver
genesymbol
Kcng2
resolver
uniprot_entry
KCNG2_RAT
resolver
amino_acid_sequence
MARLPGHPEVPGAEPGSAVRGGRGGRGARARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDELLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARATPPARGPQTSPGRALGSGRLERGRRRLRDVVENPHSGLAGKLFAYVSVAFVAVTAVGLCLSTMPDVRAEEERGECSTKCRNLFVLETVCVAWFSFEFLLRSLQAESKCAFLRTPLAIIDILAILPFYVSLLAGLAAGPTGSKMLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTVRRCAREFGLLLLFLCVAMALFAPLVHLAERELGAHRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPVLREDSTRDDSTRSASATEDSSQDPETAGAAGSLPGPVGP
uniprot
proteins
function
FUNCTION: Regulatory alpha-subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1, can modulate the kinetics and conductance-voltage relationship (PubMed:10551266). Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values (PubMed:10551266). Potassium channel subunit that does not form functional channels by itself (PubMed:10551266). {ECO:0000269|PubMed:10551266}.
uniprot
proteins
mass_dalton
52536
uniprot
proteins
protein_family
G (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv6.2/KCNG2 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
10551266
uniprot
proteins
sequence_length
480
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q14721}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P63142}.
uniprot
proteins
transmembrane_region
TRANSMEM 188..209; /note="Helical; Name=Segment S1"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 231..252; /note="Helical; Name=Segment S2"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 264..284; /note="Helical; Name=Segment S3"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 297..317; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 333..354; /note="Helical; Name=Segment S5"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 397..425; /note="Helical; Name=Segment S6"; /evidence="ECO:0000250|UniProtKB:P63142
uniprot
proteins