Actg1
entrez
287876
canonical
uniprot
P63259
canonical
ensembl
ENSRNOG00000036701
resolver
ensembl
ENSRNOG00000053452
resolver
ensembl
ENSRNOG00055029822
resolver
ensembl
ENSRNOG00060030597
resolver
ensembl
ENSRNOG00065001279
resolver
ensembl
ENSRNOG00065004754
resolver
ensp
ENSRNOP00000096150
resolver
ensp
ENSRNOP00000108101
resolver
ensp
ENSRNOP00000109636
resolver
ensp
ENSRNOP00055042614
resolver
ensp
ENSRNOP00060044215
resolver
ensp
ENSRNOP00065001174
resolver
ensp
ENSRNOP00065004707
resolver
enst
ENSRNOT00000079310
resolver
enst
ENSRNOT00000102734
resolver
enst
ENSRNOT00000108494
resolver
enst
ENSRNOT00055051673
resolver
enst
ENSRNOT00060053173
resolver
enst
ENSRNOT00065001687
resolver
enst
ENSRNOT00065006881
resolver
genesymbol
Actg1
resolver
genesymbol_syn
Actg
resolver
uniprot
P02571
resolver
uniprot
P14104
resolver
uniprot
P99022
resolver
uniprot_entry
ACTG_RAT
resolver
uniprot_sec
P02571
resolver
uniprot_sec
P14104
resolver
uniprot_sec
P99022
resolver
amino_acid_sequence
MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. May play a role in the repair of noise-induced stereocilia gaps thereby maintains hearing sensitivity following loud noise damage (By similarity). {ECO:0000250|UniProtKB:P63260, ECO:0000250|UniProtKB:P63261}.
uniprot
proteins
mass_dalton
41793
uniprot
proteins
post_translational_modification
PTM: [Actin, cytoplasmic 2]: N-terminal cleavage of acetylated methionine of immature cytoplasmic actin by ACTMAP. {ECO:0000250|UniProtKB:P63261}.; PTM: Oxidation of Met-44 and Met-47 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promote actin repolymerization. {ECO:0000250|UniProtKB:P63260}.; PTM: Monomethylation at Lys-84 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. {ECO:0000250|UniProtKB:P63261}.; PTM: [Actin, cytoplasmic 2, N-terminally processed]: N-terminal acetylation by NAA80 affects actin filament depolymerization and elongation, including elongation driven by formins. In contrast, filament nucleation by the Arp2/3 complex is not affected. {ECO:0000250|UniProtKB:P63261}.; PTM: Methylated at His-73 by SETD3. {ECO:0000250|UniProtKB:P63261}.
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
2372296
uniprot
proteins
pubmed
2402472
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P63261}.
uniprot
proteins