Q5HZE8
uniprot
Q5HZE8
canonical
amino_acid_sequence
MAAVALPLLLLLASPATPTPARDPFSPQLGDTQRCQQRCRQRHPGLPPAQPEPEGPSESPNNKAVLINACERGCRLFSICRFVARSSRPNATETECEAACTEAYVKAKEQQACSEGCWGQIPEPETQLEQKELALDPPSGSLSLRHLFTMLCSDLMSSAQDLISSTWTYSLQTDNRKTQPVVENFAFQGSRLQRVEVTWRGSHPKALEVHMDPMSPLEKVRRAKPHLKTSKAKVESEDQQESDFLSCMSRRSGLPRWVLFCCLFLSVLIILWLSCCTLVTTPGQHLKFQPLTAEQHKGLLVESNWPLYPPLPPAYEDSPPPYKLKLDLTTL
uniprot
proteins
function
FUNCTION: Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
36976
uniprot
proteins
protein_family
TMEM59 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 258..278; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins