Meox2
entrez
29279
canonical
uniprot
P39020
canonical
ensembl
ENSRNOG00000006588
resolver
ensp
ENSRNOP00000008803
resolver
enst
ENSRNOT00000008803
resolver
genesymbol
Meox2
resolver
genesymbol_syn
Gax
resolver
genesymbol_syn
Mox-2
resolver
genesymbol_syn
Mox2
resolver
uniprot
G3V6T9
resolver
uniprot_entry
G3V6T9_RAT
resolver
uniprot_entry
MEOX2_RAT
resolver
amino_acid_sequence
MEHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHRGHHHHHHHHHHHHQQQQHQALQSNWHLPQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGSSTPTGAACAPRDYGRQALSPAEVEKRSGSKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAATLQQTGDSLANDDSRDSDHSSEHAHL
uniprot
proteins
function
FUNCTION: Mesodermal transcription factor that plays a key role in somitogenesis and somitogenesis and limb muscle differentiation. Required during limb development for normal appendicular muscle formation and for the normal regulation of myogenic genes (By similarity). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle (PubMed:8098844). Also acts as a negative regulator of angiogenesis. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (By similarity). Together with TCF15, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells (By similarity). {ECO:0000250|UniProtKB:P32443, ECO:0000250|UniProtKB:P50222, ECO:0000269|PubMed:8098844}.
uniprot
proteins
mass_dalton
33605
uniprot
proteins
pubmed
8098844
uniprot
proteins
sequence_length
303
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P50222}. Nucleus speckle {ECO:0000250|UniProtKB:P50222}.
uniprot
proteins