Gins1
entrez
69270
canonical
uniprot
Q9CZ15
canonical
ensembl
ENSMUSG00000027454
resolver
ensp
ENSMUSP00000028948
resolver
enst
ENSMUST00000028948
resolver
genesymbol
Gins1
resolver
genesymbol_syn
Gins4
resolver
genesymbol_syn
Psf1
resolver
uniprot
Q8K1A2
resolver
uniprot_entry
PSF1_MOUSE
resolver
uniprot_entry
Q8K1A2_MOUSE
resolver
amino_acid_sequence
MFCEKAMELVRELHRAPEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSAGRGDLIPTVKFRHCALLRNRRCTIAYLYDRLLRIRALRWEYGSVLPNSLRFHMSAEETEWFNHYKKSLATYMRSLGGDEGLDITQDVKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHVLS
uniprot
proteins
function
FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. {ECO:0000250|UniProtKB:Q14691}.
uniprot
proteins
mass_dalton
22893
uniprot
proteins
protein_family
GINS1/PSF1 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
196
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q14691}. Chromosome {ECO:0000250|UniProtKB:Q14691}. Note=Associates with chromatin. {ECO:0000250|UniProtKB:Q14691}.
uniprot
proteins