Slc9c1
entrez
208169
canonical
uniprot
Q6UJY2
canonical
ensembl
ENSMUSG00000033210
resolver
ensp
ENSMUSP00000124969
resolver
enst
ENSMUST00000159945
resolver
genesymbol
Slc9c1
resolver
genesymbol_syn
Gm610
resolver
genesymbol_syn
Slc9a10
resolver
uniprot
E0CX34
resolver
uniprot
Q7M6Y7
resolver
uniprot_entry
SL9C1_MOUSE
resolver
uniprot_sec
E0CX34
resolver
uniprot_sec
Q7M6Y7
resolver
amino_acid_sequence
MEMEEISENLTASHSIKLTNMWLELLKSVFLSTPQDLPEIILILSLICTVGAFLNMHLKDFPIPLPVILFLIGCCFEILSFASTQIQIYADAIQWMDPDIFFGIFTPVIIFNVAFDMDIYMLQKLFWQILVITIPGFLINYTLILWYLQSVNKLSLKTVPWLLFSAVLISSDPMLTSASIRDLGLSRSLTNLINGESLLTSVLSLVIYSGVVHIRFKSKSVNHTLAHKVMSTAWSYIVESFITGIVFTKVIQLWMATIFGDDVNHITLIFSVLYLIFYVCELVGMSGIFTLATIGLFLNSTSFKPGVEAFLLEFWNCLSFIGFLMVFTFIGLLIPAHTYLHISFSDVYYSLNIYFTLIVLRLLVFLLMSPILSRLGHGFSWRWAFIMVWSEMKGTPNINMALLLAYSDISLGSERERSQILFHGVSVCVITLIVNRFILPMAVTKLGLRDVTSTKYKSVYYTFQHFQELTKSTAMALKFDKDLANADWNMVDNAIILQNPYAMNQEEITEHQKVKCPDCNKEIDETLNIEAMELTNRRLLSAQIASYQRQYRNEVLSQSAVQVLVGAAGSFGEKKGEYMSPENIKNFSESKKLLSFLRKLLLNWVYNTKKDKGVPSRYMFLHACHRIVFTNEFEYTGYLVVLMSTYPMIICWISRLKDIYDNEIKCANYYFLAFYILEALLKVAAMRKEFFSHTWLLFELGITLVGVLDIILIETDSISYNFDLTETVVFMNVIRLLRILRILKLVTPKLLQIIDKRMSQQISFRYSILKGYVQGEMDVLNIIDQIASSKQTKQILLKRVMRNMEHAMKELGYLEYDHPEIAVTMKTKEEINVMLNMAREIVKAFRSKGIIHKVEGTEINKLIMAKKIQVLDLQSVIQPFNVEEAPCNIPWLSEDPEAITFIQEKAKVVTFDCGNNIFEEGDEPEGIYVIISGMVKLKRSKPHLEMERVSAESEIKIHPLPHTEYLLSGEIIGELNCLTKERMQYSATCKTVVETYFIPISHLYEGFEKRCPNMKHKMWQKIGLAITAQKIREHLSFEDWNYKLQLKLCNAFIRDIPKSMKTDIYDETVTHVVLIHGSAEDCQLRKIYKAPFLIPVTCHQIQGMEDFTKVMIIQTSIAVRKFRWNVRKYIPPRRISMKPDSERESFETLDETSEEDNGKKENQENEELIEENINI
uniprot
proteins
function
FUNCTION: Sperm-specific solute carrier involved in intracellular pH regulation of spermatozoa (PubMed:14634667). Required for sperm motility and fertility (PubMed:14634667). Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization (PubMed:14634667). Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (ADCY10) (PubMed:17517652). {ECO:0000269|PubMed:14634667, ECO:0000269|PubMed:17517652}.
uniprot
proteins
mass_dalton
135545
uniprot
proteins
protein_family
Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family
uniprot
proteins
pubmed
12783626
uniprot
proteins
pubmed
14634667
uniprot
proteins
pubmed
17517652
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
37669933
uniprot
proteins
pubmed
41091759
uniprot
proteins
sequence_length
1175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:14634667}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..59; /note="Helical; Name=TM1"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 65..82; /note="Helical; Name=TM2"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 99..115; /note="Helical; Name=TM3"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 126..151; /note="Helical; Name=TM4"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 158..183; /note="Helical; Name=TM5"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 187..212; /note="Helical; Name=TM6"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 226..257; /note="Helical; Name=TM7, linker"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 262..283; /note="Helical; Name=TM8"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 287..300; /note="Helical; Name=TM9"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 308..339; /note="Helical; Name=TM10"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 345..374; /note="Helical; Name=TM11"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 381..411; /note="Helical; Name=TM12"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 416..446; /note="Helical; Name=TM13"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 633..653; /note="Helical; Name=S1"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 658..684; /note="Helical; Name=S2"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 692..716; /note="Helical; Name=S3"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 725..751; /note="Helical; Name=S4"; /evidence="ECO:0000250|UniProtKB:A3RL54
uniprot
proteins