Akap4
entrez
11643
canonical
uniprot
Q60662
canonical
ensembl
ENSMUSG00000050089
resolver
ensp
ENSMUSP00000050962
resolver
ensp
ENSMUSP00000111417
resolver
genesymbol
Akap4
resolver
genesymbol_syn
Akap82
resolver
genesymbol_syn
Fsc1
resolver
uniprot
A1L3T6
resolver
uniprot
B1AXM7
resolver
uniprot
Q60630
resolver
uniprot
Q8R2G7
resolver
uniprot_entry
A1L3T6_MOUSE
resolver
uniprot_entry
AKAP4_MOUSE
resolver
uniprot_sec
B1AXM7
resolver
uniprot_sec
Q60630
resolver
uniprot_sec
Q8R2G7
resolver
amino_acid_sequence
MIAYCGTTTMSDDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVSTLNVEDKDSKGAAGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDLQKYALGFQHALSPSASSCKHKVGDLEGDYSKIPSENCYSVYADQVNFDYLNKGPQNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPEGECSMDDLSFYVNRLSSLVIQMARKEIKDKLEGGSKCLHHSMYTSGDKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEDCRDGRKTFLYSEMCNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGKPIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNAADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTNDPKCKNQSLEFSAMKAEMKGKDKCKSKADPCCKSLTSAERVSEHILKESLTMWNNQKQGNQGKVTNKVCCTSKDEKREKISPSTDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKCGGGQSSKSLSMKHFETRGAPGPSTCMKENQLESQKMDMSNMVLSLIQKLLSESPFSCDELTESDNKRCCDPRSSKAAPMAKRPEEQCQDNAELDFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQAALVGSGSRCGRDAMMSQNYSETPGPEVIVNNQCSTTNLQKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLDEAVGNMARKQLLDWLLANL
uniprot
proteins
function
FUNCTION: Major structural component of sperm fibrous sheath (PubMed:12167408). Plays a role in sperm motility (PubMed:12167408, PubMed:31255637). {ECO:0000269|PubMed:12167408, ECO:0000269|PubMed:31255637}.
uniprot
proteins
mass_dalton
93796
uniprot
proteins
mutagenesis
MUTAGEN 428; /note="R->H: Knockin mice display male subfertility due to decreased sperm motility."; /evidence="ECO:0000269|PubMed:38050179
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by STK33 during sperm flagella assembly. {ECO:0000269|PubMed:37146716}.
uniprot
proteins
protein_family
AKAP110 family
uniprot
proteins
pubmed
12167408
uniprot
proteins
pubmed
12606363
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23446454
uniprot
proteins
pubmed
31255637
uniprot
proteins
pubmed
35618043
uniprot
proteins
pubmed
37146716
uniprot
proteins
pubmed
38050179
uniprot
proteins
pubmed
7711182
uniprot
proteins
pubmed
8088444
uniprot
proteins
pubmed
9852104
uniprot
proteins
sequence_length
849
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q5JQC9}. Note=Localizes to the principle piece of the sperm flagellum. {ECO:0000250|UniProtKB:Q5JQC9}.
uniprot
proteins