Shld1
entrez
73747
canonical
uniprot
Q9D112
canonical
ensembl
ENSMUSG00000044991
resolver
ensp
ENSMUSP00000057009
resolver
ensp
ENSMUSP00000105759
resolver
ensp
ENSMUSP00000293985
resolver
enst
ENSMUST00000061891
resolver
enst
ENSMUST00000110132
resolver
genesymbol
Shld1
resolver
genesymbol_syn
1110034G24Rik
resolver
genesymbol_syn
RINN3
resolver
uniprot
A2AW53
resolver
uniprot
B2RR16
resolver
uniprot_entry
B2RR16_MOUSE
resolver
uniprot_entry
SHLD1_MOUSE
resolver
uniprot_sec
A2AW53
resolver
amino_acid_sequence
MESQAATPSSLSGESCTLDLPAVCDTSSYEASQRVSQGSSNSLSSLESHPFLSSSTTDPDSNSLNTEQKGSWDSENFWLDPSSKGQLETNEEEDGLRKSLDRFYEAFAHPLPGSGDPLSASVCQCLSQTISELEGQESQRYALRSFQMAQVIFSRDGCSILQRHSRDTRFYPLEQEGSSVDDEEPTPGLSREVIRFLLEQTVMKDS
uniprot
proteins
function
FUNCTION: Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. {ECO:0000250|UniProtKB:Q8IYI0}.
uniprot
proteins
mass_dalton
22697
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
206
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Chromosome {ECO:0000250|UniProtKB:Q8IYI0}.
uniprot
proteins