Tanc1
entrez
311055
canonical
uniprot
Q6F6B3
canonical
ensembl
ENSRNOG00000025394
resolver
ensp
ENSRNOP00000033136
resolver
enst
ENSRNOT00000038983
resolver
genesymbol
Tanc1
resolver
genesymbol_syn
Tanc
resolver
uniprot
G3V917
resolver
uniprot_entry
G3V917_RAT
resolver
uniprot_entry
TANC1_RAT
resolver
amino_acid_sequence
MLKAVLKKSREGVKGSKKEAGGDFGSETPTLSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSHLTQSRANKKSPGPVRKPKYVESPRVPGDPVMIPFREGSKPAEPIETEAKVDNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRLDNCSPVAEEETTGSAESVLPKAESSAGDGPVPYSQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHSTAGARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFQQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQVASSSPSSSLKTSDPTHDLPGTPLLSPSSSTSALSAARTPPGPGTVDSQRPREDAVKYLASRVVAYHYCQADNTYTCLVPEFVHSIATLLCRSHQLAAYRDLLIREPQLQSMLNLRSCVQDPVAAFKRGILEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDHGDTLSSFITKIIPKFPPWLKLIVTVRADFQEIISTLPFVKLSLDDFPGNQDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSRLVLRNLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQKMEALSCFLIKKRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTVELGHHILKAHIFKGLSKKTGVSSSHPQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLTKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSAVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKLEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVQLLLDRGCDVNPNDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATFKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGPGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPTNQEIKRLLARVEEECKQLQRNQQQKQQAPLPAPPNDSDNDEEAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRPASPQSWAGISKSLRETVAQPGLVMQPTKQAQIVKTNQHLGSGQSSMRNSNTKVQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFSTGTGCGHFGDRLGPSQSLQLQRGESGTAYPLPSKVKAAERLLAHASVAVDMALPSQGGPVSCSDVRHPASLSSSGSSGSPSSSVKMSSSTSSLTSSSSVSDGFKAQGPDCRIRDRGTTQVQGGTAEHRPRNTPFMGIMDKIARFQQQVNPPSRSWHCPVTEGLLTNTATAAGLQTNSEKPALKPGGYCSQAKPCSVPPLGMGVHNGAQVKELEENKCQVPALCQDNRKTKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV
uniprot
proteins
function
FUNCTION: May be a scaffold component in the postsynaptic density.
uniprot
proteins
mass_dalton
200507
uniprot
proteins
mutagenesis
MUTAGEN 1849; /note="Missing: Abolishes interaction with DLG1, DLG4 and HOMER1."; /evidence="ECO:0000269|PubMed:15673434
uniprot
proteins
post_translational_modification
PTM: Phosphorylated; by MINK1 and TNIK upon stimulation by RAP2A. {ECO:0000250}.
uniprot
proteins
protein_family
TANC family
uniprot
proteins
pubmed
15673434
uniprot
proteins
pubmed
18930710
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1849
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic density {ECO:0000269|PubMed:15673434}. Note=Largly colocalizes with SYP/synaptophysin, DLG1, DLG4 and GRIA1 at synaptic sites.
uniprot
proteins