GART
entrez
2618
canonical
uniprot
P22102
canonical
ensembl
ENSG00000159131
resolver
ensembl
ENSG00000262473
resolver
ensp
ENSP00000354388
resolver
ensp
ENSP00000371236
resolver
ensp
ENSP00000371253
resolver
ensp
ENSP00000371261
resolver
ensp
ENSP00000459391
resolver
ensp
ENSP00000459532
resolver
ensp
ENSP00000461700
resolver
ensp
ENSP00000550432
resolver
ensp
ENSP00000550433
resolver
ensp
ENSP00000550434
resolver
enst
ENST00000571089
resolver
enst
ENST00000573055
resolver
enst
ENST00000575273
resolver
genesymbol
GART
resolver
genesymbol_syn
PGFT
resolver
genesymbol_syn
PRGS
resolver
hgnc
HGNC:4163
resolver
uniprot
A8K945
resolver
uniprot
A8KA32
resolver
uniprot
D3DSF3
resolver
uniprot
D3DSF4
resolver
uniprot
O14659
resolver
uniprot
Q52M77
resolver
uniprot
Q59HH3
resolver
uniprot_entry
PUR2_HUMAN
resolver
uniprot_entry
Q59HH3_HUMAN
resolver
uniprot_sec
A8K945
resolver
uniprot_sec
A8KA32
resolver
uniprot_sec
D3DSF3
resolver
uniprot_sec
D3DSF4
resolver
uniprot_sec
O14659
resolver
uniprot_sec
Q52M77
resolver
amino_acid_sequence
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE
uniprot
proteins
ec_number
2.1.2.2
uniprot
proteins
ec_number
6.3.3.1
uniprot
proteins
ec_number
6.3.4.13
uniprot
proteins
function
FUNCTION: Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway. {ECO:0000305|PubMed:12450384, ECO:0000305|PubMed:12755606, ECO:0000305|PubMed:20631005, ECO:0000305|PubMed:2183217}.
uniprot
proteins
mass_dalton
107767
uniprot
proteins
pathway_participation
PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. {ECO:0000305|PubMed:12450384}.; PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2. {ECO:0000305|PubMed:2183217}.; PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1. {ECO:0000305|PubMed:2183217}.
uniprot
proteins
protein_family
GARS family; AIR synthase family; GART family
uniprot
proteins
pubmed
12450384
uniprot
proteins
pubmed
12755606
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
16026156
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
20631005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
2147474
uniprot
proteins
pubmed
2183217
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9224613
uniprot
proteins
sequence_length
1010
uniprot
proteins