Mttp
entrez
17777
canonical
uniprot
O08601
canonical
ensembl
ENSMUSG00000028158
resolver
ensp
ENSMUSP00000029805
resolver
ensp
ENSMUSP00000096179
resolver
ensp
ENSMUSP00000240131
resolver
ensp
ENSMUSP00000240135
resolver
genesymbol
Mttp
resolver
genesymbol_syn
Mtp
resolver
uniprot
B2CXA7
resolver
uniprot
Q3UJA0
resolver
uniprot
Q91X33
resolver
uniprot_entry
MTP_MOUSE
resolver
uniprot_sec
B2CXA7
resolver
uniprot_sec
Q3UJA0
resolver
uniprot_sec
Q91X33
resolver
amino_acid_sequence
MILLAVLFLCFFSSYSASVKGHTTGLSLNNERLYKLTYSTEVFLDGGKGKPQDSVGYKISSDVDVVLLWRNPDGDDDQVIQVTITAVNVENAGQQRGEKSIFQGKSTPKIIGKDNLEALQRPMLLHLVRGKVKEFYSYENEPVGIENLKRGLASLFQMQLSSGTTNEVDISGDCKVTYQAQQDKVVKIKALDTCKIERSGFTTANQVLGVSSKATSVTTYKIEDSFVTAVLAEETRAFALNFQQTIAGKIVSKQKLELKTTEAGPRMIPGKQVAGVIKAVDSKYKAIPIVGQVLERVCKGCPSLAEHWKSIRKNLEPENLSKAEAVQSFLAFIQHLRTSRREEILQILKAEKKEVLPQLVDAVTSAQTPDSLEAILDFLDFKSDSSIILQERFLYACGFATHPDEELLRALLSKFKGSFASNDIRESVMIIIGALVRKLCQNEGCKLKAVVEAKKLILGGLEKPEKKEDTTMYLLALKNALLPEGIPLLLKYAEAGEGPVSHLATTVLQRYDVSFITDEVKKTLNRIYHQNRKVHEKTVRTTAAAVILKNPSYMDVKNILLSIGELPKEMNKYMLTVVQDILHFEMPASKMIRRVLKEMAVHNYDRFSKSGSSSAYTGYVERSPRAASTYSLDILYSGSGILRRSNLNIFQYIGKAELHGSQVVIEAQGLEGLIAATPDEGEENLDSYAGMSAILFDVQLRPVTFFNGYSDLMSKMLSASGDPVSVVKGLILLIDHSQDIQLQSGLKANMEIQGGLAIDISGSMEFSLWYRESKTRVKNRVAVVITSDVTVDASFVKAGVESRAETEAGLEFISTVQFSQYPFLVCMQMDKAEAPLRQFETKYERLSTGRGYVSRRRKESLVAGCELPLHQENSEMCNVVFPPQPESDNSGGWF
uniprot
proteins
function
FUNCTION: Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:15897609, PubMed:16478722, PubMed:18502767, PubMed:33168624). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:10713055, PubMed:17635917, PubMed:18502767, PubMed:33168624, PubMed:9502759). May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (PubMed:18502767). {ECO:0000269|PubMed:10713055, ECO:0000269|PubMed:15897609, ECO:0000269|PubMed:16478722, ECO:0000269|PubMed:17635917, ECO:0000269|PubMed:18502767, ECO:0000269|PubMed:33168624, ECO:0000269|PubMed:9502759}.; FUNCTION: [Isoform 2]: Critical for the development of natural killer T (NKT) cells (PubMed:17312007). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:17635917). {ECO:0000269|PubMed:17312007, ECO:0000269|PubMed:17635917}.
uniprot
proteins
mass_dalton
99099
uniprot
proteins
post_translational_modification
PTM: [Isoform 2]: Cleaved by signal peptidase between residues Gln-33 and Asn-34. {ECO:0000269|PubMed:17312007, ECO:0000269|PubMed:17635917}.
uniprot
proteins
pubmed
10713055
uniprot
proteins
pubmed
10744773
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15897609
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16478722
uniprot
proteins
pubmed
17312007
uniprot
proteins
pubmed
17635917
uniprot
proteins
pubmed
18497885
uniprot
proteins
pubmed
18502767
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24353284
uniprot
proteins
pubmed
33168624
uniprot
proteins
pubmed
8660984
uniprot
proteins
pubmed
9502759
uniprot
proteins
sequence_length
894
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:33168624}.; SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum {ECO:0000269|PubMed:17312007, ECO:0000269|PubMed:17635917}. Golgi apparatus {ECO:0000250|UniProtKB:P55157}. Note=Colocalizes with P4HB/PDI in the endoplasmic reticulum (By similarity). {ECO:0000250|UniProtKB:P55157}.; SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum {ECO:0000269|PubMed:17312007}. Golgi apparatus {ECO:0000269|PubMed:17635917}.
uniprot
proteins