P08508
uniprot
P08508
canonical
amino_acid_sequence
MFQNAHSGSQWLLPPLTILLLFAFADRQSAALPKAVVKLDPPWIQVLKEDMVTLMCEGTHNPGNSSTQWFHNGRSIRSQVQASYTFKATVNDSGEYRCQMEQTRLSDPVDLGVISDWLLLQTPQRVFLEGETITLRCHSWRNKLLNRISFFHNEKSVRYHHYKSNFSIPKANHSHSGDYYCKGSLGSTQHQSKPVTITVQDPATTSSISLVWYHTAFSLVMCLLFAVDTGLYFYVRRNLQTPREYWRKSLSIRKHQAPQDK
uniprot
proteins
function
FUNCTION: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor which binds to IgG1, IgG2a and IgG2b (PubMed:17558411). Mediates neutrophil activation by IgG complexes redundantly with Fcgr4 (PubMed:18097064). {ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064}.
uniprot
proteins
mass_dalton
30036
uniprot
proteins
pubmed
12393695
uniprot
proteins
pubmed
17558411
uniprot
proteins
pubmed
18097064
uniprot
proteins
pubmed
2946078
uniprot
proteins
pubmed
8070412
uniprot
proteins
sequence_length
261
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17558411}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 216..235; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins