Atp5mf
entrez
690441
canonical
uniprot
D3ZAF6
canonical
genesymbol
Atp5mf
resolver
genesymbol_syn
Atp5j2
resolver
uniprot_entry
ATPK_RAT
resolver
amino_acid_sequence
MASIVPLKEKKLMEVKLRELPSWILMRDFTPSGIAGAFRRGYDRYYNKYINVRKGSISGINMVLAAYVVFSYCISYKELKHERRRKYH
uniprot
proteins
function
FUNCTION: Subunit f, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (By similarity). {ECO:0000250|UniProtKB:P19483, ECO:0000250|UniProtKB:P56134}.
uniprot
proteins
mass_dalton
10452
uniprot
proteins
protein_family
ATPase F chain family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
17575325
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
88
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 62..79; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P56134
uniprot
proteins