Cplx2
entrez
116657
canonical
uniprot
P84087
canonical
ensembl
ENSRNOG00000000105
resolver
ensembl
ENSRNOG00055014037
resolver
ensembl
ENSRNOG00060017677
resolver
ensembl
ENSRNOG00065010425
resolver
ensp
ENSRNOP00000072664
resolver
ensp
ENSRNOP00055019682
resolver
ensp
ENSRNOP00060024398
resolver
ensp
ENSRNOP00065012918
resolver
enst
ENSRNOT00000091046
resolver
enst
ENSRNOT00055024121
resolver
enst
ENSRNOT00060030229
resolver
enst
ENSRNOT00065016877
resolver
genesymbol
Cplx2
resolver
uniprot
O09056
resolver
uniprot
Q13329
resolver
uniprot
Q28184
resolver
uniprot
Q64386
resolver
uniprot_entry
CPLX2_RAT
resolver
uniprot_sec
O09056
resolver
uniprot_sec
Q13329
resolver
uniprot_sec
Q28184
resolver
uniprot_sec
Q64386
resolver
amino_acid_sequence
MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK
uniprot
proteins
function
FUNCTION: Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis (PubMed:15870114). {ECO:0000269|PubMed:15870114}.
uniprot
proteins
mass_dalton
15394
uniprot
proteins
post_translational_modification
PTM: Ser-93 is dephosphorylated by PP2A.
uniprot
proteins
protein_family
Complexin/synaphin family
uniprot
proteins
pubmed
10051208
uniprot
proteins
pubmed
10430466
uniprot
proteins
pubmed
10777504
uniprot
proteins
pubmed
11751907
uniprot
proteins
pubmed
15870114
uniprot
proteins
pubmed
15911881
uniprot
proteins
pubmed
16499873
uniprot
proteins
pubmed
7553862
uniprot
proteins
pubmed
7654227
uniprot
proteins
pubmed
9753100
uniprot
proteins
sequence_length
134
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:7654227}. Presynapse {ECO:0000269|PubMed:15911881, ECO:0000269|PubMed:7654227}. Nucleus. Perikaryon {ECO:0000269|PubMed:9753100}. Note=Translocated from the perikaryon to the presynaptic terminals during maturation of neuronal cells (PubMed:7654227). In mast cells, cytosol and nucleus. Becomes enriched near plasma membrane following stimulation. {ECO:0000269|PubMed:7654227}.
uniprot
proteins