Ccl17
entrez
117518
canonical
uniprot
Q9ERE0
canonical
ensembl
ENSRNOG00000016278
resolver
ensp
ENSRNOP00000021842
resolver
enst
ENSRNOT00000021842
resolver
genesymbol
Ccl17
resolver
genesymbol_syn
Abcd-2
resolver
genesymbol_syn
Tarc
resolver
uniprot
E9PTY9
resolver
uniprot_entry
CCL17_RAT
resolver
uniprot_entry
E9PTY9_RAT
resolver
amino_acid_sequence
MMSLQMLLLAALLLGTSLQHASAARATNVGRECCLDYFKGAIPIRKLVTWFRTSVECPKDAIVFETVQGRLICTDPKDKHVKKAIRHLKNQRL
uniprot
proteins
function
FUNCTION: Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation (By similarity). In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound (By similarity). {ECO:0000250|UniProtKB:Q92583, ECO:0000250|UniProtKB:Q9WUZ6}.
uniprot
proteins
mass_dalton
10480
uniprot
proteins
protein_family
Intercrine beta (chemokine CC) family
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
93
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q92583}.
uniprot
proteins