Aen
entrez
68048
canonical
uniprot
Q9CZI9
canonical
ensembl
ENSMUSG00000030609
resolver
ensp
ENSMUSP00000103044
resolver
ensp
ENSMUSP00000103046
resolver
ensp
ENSMUSP00000103048
resolver
genesymbol
Aen
resolver
genesymbol_syn
Isg20l1
resolver
uniprot
Q3TKV9
resolver
uniprot
Q8BTJ8
resolver
uniprot
Q8C095
resolver
uniprot_entry
AEN_MOUSE
resolver
uniprot_sec
Q3TKV9
resolver
uniprot_sec
Q8BTJ8
resolver
uniprot_sec
Q8C095
resolver
amino_acid_sequence
MVAGEVPESTQCPSLTSLNTKDVVRRRHKRRSRQHQRFMARKALLQEQELLSTAPGPGLCLLPSPSQMPAVTEASDSRRQRPKARSGSNGLCSKKSVPREAPRPGPIKCVAIDCEMVGTGPQGRVSELARCSVVSYSGDVLYDKYIRPEMPIVDYRTRWSGITRQHMHKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNLLSQPSSLIRTRVSLKDLALNLLHKKIQVGHQGHSSVEDAMTAMELYQLVEVQWEQQVASSAQAPAEDRGPDSSTDVEQYMDDQYWPEDLTQSTGAETNGGPDRQEGEEGQGARSAPP
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
336
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction (By similarity). {ECO:0000250}.
uniprot
proteins