Rph3al
entrez
380714
canonical
uniprot
Q768S4
canonical
ensembl
ENSMUSG00000020847
resolver
ensp
ENSMUSP00000021208
resolver
ensp
ENSMUSP00000064202
resolver
ensp
ENSMUSP00000104058
resolver
ensp
ENSMUSP00000113869
resolver
ensp
ENSMUSP00000213718
resolver
ensp
ENSMUSP00000213719
resolver
ensp
ENSMUSP00000213720
resolver
ensp
ENSMUSP00000213721
resolver
genesymbol
Rph3al
resolver
genesymbol_syn
Gm1753
resolver
genesymbol_syn
Noc2
resolver
uniprot
Q9D353
resolver
uniprot_entry
RPH3L_MOUSE
resolver
uniprot_sec
Q9D353
resolver
amino_acid_sequence
MADTIFSSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRSQCLSPGELEIILQVIQRAERLDILEQQRIGRLVERLETMQRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPVEPTETQPPSAETSRVYTWARGRVVSSDSDSDSDLSSSSLEDRPLPSGVKGTKGDKPRGDSGASMESPRLGPARPPSHLSGSQSSLGSEAGTGATEPQGGTPAQPEPRVPGKRHTWATPRY
uniprot
proteins
function
FUNCTION: Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Regulates the exocytosis of dense-core vesicles in neuroendocrine cells through interaction with RAB27A. Acts as a potential RAB3B effector protein in epithelial cells. {ECO:0000269|PubMed:14722103, ECO:0000269|PubMed:15159548}.
uniprot
proteins
mass_dalton
33259
uniprot
proteins
mutagenesis
MUTAGEN 51..55; /note="ELEII->ALEIA: Loss of binding to RAB27A, remaining cytoplasmic."; /evidence="ECO:0000269|PubMed:14722103
uniprot
proteins
pubmed
12578829
uniprot
proteins
pubmed
14722103
uniprot
proteins
pubmed
15159548
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16835753
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
302
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Note=Recruited to the exocytic secretory vesicles by RAB27A.
uniprot
proteins