Sumo3
entrez
20610
canonical
uniprot
Q9Z172
canonical
ensembl
ENSMUSG00000020265
resolver
ensp
ENSMUSP00000020501
resolver
ensp
ENSMUSP00000097136
resolver
ensp
ENSMUSP00000133466
resolver
ensp
ENSMUSP00000134416
resolver
enst
ENSMUST00000129492
resolver
enst
ENSMUST00000141228
resolver
genesymbol
Sumo3
resolver
genesymbol_syn
Smt3a
resolver
genesymbol_syn
Smt3h1
resolver
uniprot
G3UWX9
resolver
uniprot
G3UZA7
resolver
uniprot
Q14C17
resolver
uniprot
Q3TBL9
resolver
uniprot
Q3UDI5
resolver
uniprot_entry
G3UWX9_MOUSE
resolver
uniprot_entry
G3UZA7_MOUSE
resolver
uniprot_entry
SUMO3_MOUSE
resolver
uniprot_sec
Q14C17
resolver
uniprot_sec
Q3TBL9
resolver
uniprot_sec
Q3UDI5
resolver
amino_acid_sequence
MSEEKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGSASRGSVPTPNRCPDLCY
uniprot
proteins
function
FUNCTION: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. Plays a role in the regulation of sumoylation status of SETX (By similarity). {ECO:0000250|UniProtKB:P55854}.
uniprot
proteins
mass_dalton
12430
uniprot
proteins
post_translational_modification
PTM: Polymeric chains can be formed through Lys-11 cross-linking. {ECO:0000250}.; PTM: Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function. {ECO:0000250}.
uniprot
proteins
protein_family
SUMO subfamily
uniprot
proteins
protein_family
Ubiquitin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18644859
uniprot
proteins
pubmed
9891849
uniprot
proteins
sequence_length
110
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Nucleus, PML body {ECO:0000269|PubMed:18644859}.
uniprot
proteins