RNASE2
entrez
6036
canonical
uniprot
P10153
canonical
ensembl
ENSG00000169385
resolver
ensp
ENSP00000303276
resolver
enst
ENST00000304625
resolver
genesymbol
RNASE2
resolver
genesymbol_syn
EDN
resolver
genesymbol_syn
RNS2
resolver
hgnc
HGNC:10045
resolver
uniprot
Q52M39
resolver
uniprot
Q9H2B7
resolver
uniprot
Q9UCG7
resolver
uniprot_entry
RNAS2_HUMAN
resolver
uniprot_sec
Q52M39
resolver
uniprot_sec
Q9H2B7
resolver
uniprot_sec
Q9UCG7
resolver
amino_acid_sequence
MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
uniprot
proteins
ec_number
4.6.1.18
uniprot
proteins
function
FUNCTION: This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. {ECO:0000269|PubMed:12578357, ECO:0000269|PubMed:3458170}.
uniprot
proteins
mass_dalton
18354
uniprot
proteins
post_translational_modification
PTM: A particular signal processing and glycosylation pattern may differentiate the UpI2 RNase, found specifically in pregnant women urine, from other nonsecretory RNases. {ECO:0000269|PubMed:7947762, ECO:0000269|PubMed:9450956}.
uniprot
proteins
protein_family
Pancreatic ribonuclease family
uniprot
proteins
pubmed
11102386
uniprot
proteins
pubmed
11154698
uniprot
proteins
pubmed
12578357
uniprot
proteins
pubmed
12855582
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15755456
uniprot
proteins
pubmed
1587793
uniprot
proteins
pubmed
16401072
uniprot
proteins
pubmed
18694936
uniprot
proteins
pubmed
2387583
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2591744
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
2734298
uniprot
proteins
pubmed
2745977
uniprot
proteins
pubmed
3166997
uniprot
proteins
pubmed
3182786
uniprot
proteins
pubmed
3458170
uniprot
proteins
pubmed
3926759
uniprot
proteins
pubmed
7547911
uniprot
proteins
pubmed
7947762
uniprot
proteins
pubmed
8471426
uniprot
proteins
pubmed
8759319
uniprot
proteins
pubmed
9450956
uniprot
proteins
sequence_length
161
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000305}. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
uniprot
proteins