PDE1A
entrez
5136
canonical
uniprot
P54750
canonical
ensembl
ENSG00000115252
resolver
ensp
ENSP00000309269
resolver
ensp
ENSP00000350858
resolver
ensp
ENSP00000386767
resolver
ensp
ENSP00000387037
resolver
ensp
ENSP00000410309
resolver
ensp
ENSP00000512257
resolver
ensp
ENSP00000512258
resolver
ensp
ENSP00000778711
resolver
ensp
ENSP00000784152
resolver
genesymbol
PDE1A
resolver
hgnc
HGNC:8774
resolver
uniprot
B7Z226
resolver
uniprot
B7Z3A7
resolver
uniprot
B7Z7A2
resolver
uniprot
D3DPG5
resolver
uniprot
Q86VZ0
resolver
uniprot
Q9C0K8
resolver
uniprot
Q9C0K9
resolver
uniprot
Q9C0L0
resolver
uniprot
Q9C0L1
resolver
uniprot
Q9C0L2
resolver
uniprot
Q9C0L3
resolver
uniprot
Q9C0L4
resolver
uniprot
Q9UFX3
resolver
uniprot
Q9Y633
resolver
uniprot_entry
B7Z226_HUMAN
resolver
uniprot_entry
B7Z3A7_HUMAN
resolver
uniprot_entry
B7Z7A2_HUMAN
resolver
uniprot_entry
PDE1A_HUMAN
resolver
uniprot_entry
Q9Y633_HUMAN
resolver
uniprot_sec
D3DPG5
resolver
uniprot_sec
Q86VZ0
resolver
uniprot_sec
Q9C0K8
resolver
uniprot_sec
Q9C0K9
resolver
uniprot_sec
Q9C0L0
resolver
uniprot_sec
Q9C0L1
resolver
uniprot_sec
Q9C0L2
resolver
uniprot_sec
Q9C0L3
resolver
uniprot_sec
Q9C0L4
resolver
uniprot_sec
Q9UFX3
resolver
activity_regulation
ACTIVITY REGULATION: Type I PDE are activated by the binding of calmodulin in the presence of Ca(2+). {ECO:0000250|UniProtKB:Q61481}.
uniprot
proteins
amino_acid_sequence
MGSSATEIEELENTTFKYLTGEQTEKMWQRLKGILRCLVKQLERGDVNVVDLKKNIEYAASVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIFVERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLIEEASKAETSSYVASSSTTIVGLHIADALRRSNTKGSMSDGSYSPDYSLAAVDLKSFKNNLVDIIQQNKERWKELAAQEARTSSQKCEFIHQ
uniprot
proteins
ec_number
3.1.4.17
uniprot
proteins
function
FUNCTION: Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. {ECO:0000269|PubMed:8557689}.
uniprot
proteins
mass_dalton
61252
uniprot
proteins
protein_family
Cyclic nucleotide phosphodiesterase family
uniprot
proteins
protein_family
PDE1 subfamily
uniprot
proteins
pubmed
11342109
uniprot
proteins
pubmed
11747989
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959763
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
8557689
uniprot
proteins
sequence_length
535
uniprot
proteins