Pkn3
entrez
263803
canonical
uniprot
Q8K045
canonical
ensembl
ENSMUSG00000026785
resolver
ensp
ENSMUSP00000041025
resolver
enst
ENSMUST00000045246
resolver
genesymbol
Pkn3
resolver
genesymbol_syn
Pknbeta
resolver
uniprot
Q3UQS3
resolver
uniprot_entry
PKN3_MOUSE
resolver
uniprot_entry
Q3UQS3_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Two specific sites, Thr-707 (activation loop of the kinase domain) and Thr-849 (turn motif), need to be phosphorylated for its full activation. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MEHRKPGTGQRAPKDEKEMVRRAIQKELKIKEGMENMRRVATDRRHLGHVQQLLRASNRRLEQLHGELRELHAQVLLPASAEPVTSEPQPRAEQSRARLSEALHRQLQVELKVKQGAENMIHTCASGTPKERKLLAAAQQMLKDSQLKVALLRMKISSLESSGSPEPGPDLLAEELQHRLRVEAAVAAGAKNVVKLLGGQRMQDRKALAEAQAQLQESSQKLDLLRLALELLLERLPPTHSLRSRVTQELWMAMLGNPQPLGTLVKPIALTGTLQVRLLGCKDLLVAVPGRSPMAVLAGSPSESWLRTRSRQQRGGGELASEVLAVLKVDNRVVGQTGWGLVAEKSWDQSFIISLDRARELEIGVHWRDWRQLCGVAFLKLEDFLDNACHQLSLSLVPQGRLFAQVTFCEPVIERRPRLQRQRCIFSKRRGRDFMRASQMNLSMAAWGRLVMSLLPPCSSPNTASPPKGRPSTAVCGTPSAASPSNFLPMKTLSKEDTKPPPKPPRLYLQEPAPGTPCTKRPHMDPRPAVVPALAALSTRKPPRLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVGRTGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQIHEDVFPEPQACFYLACVVLGLQFLHEKRIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSADVPCPHFLSVQGLELIQKLLQKSPEKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVSQSSLTARQQAAFRDFDFVSEQFLES
uniprot
proteins
ec_number
2.7.11.13
uniprot
proteins
function
FUNCTION: Contributes to invasiveness in malignant prostate cancer. {ECO:0000269|PubMed:15282551}.
uniprot
proteins
mass_dalton
97881
uniprot
proteins
post_translational_modification
PTM: Autophosphorylated. {ECO:0000250}.
uniprot
proteins
protein_family
AGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
PKC subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
15282551
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
878
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Nuclear and perinuclear Golgi region. {ECO:0000250}.
uniprot
proteins