CARD10
entrez
29775
canonical
uniprot
Q9BWT7
canonical
ensembl
ENSG00000100065
resolver
ensp
ENSP00000251973
resolver
genesymbol
CARD10
resolver
genesymbol_syn
CARMA3
resolver
hgnc
HGNC:16422
resolver
uniprot
Q14CQ8
resolver
uniprot
Q5TFG6
resolver
uniprot
Q8NC81
resolver
uniprot
Q9UGR5
resolver
uniprot
Q9UGR6
resolver
uniprot
Q9Y3H0
resolver
uniprot_entry
CAR10_HUMAN
resolver
uniprot_sec
Q14CQ8
resolver
uniprot_sec
Q5TFG6
resolver
uniprot_sec
Q8NC81
resolver
uniprot_sec
Q9UGR5
resolver
uniprot_sec
Q9UGR6
resolver
uniprot_sec
Q9Y3H0
resolver
amino_acid_sequence
MPGRAEAGEAEEEAGAGSGSEAEEDALWERIEGVRHRLARALNPAKLTPYLRQCRVIDEQDEEEVLSTYRFPCRVNRTGRLMDILRCRGKRGYEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRVLEEERAGLEQRLRDQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPPPGAEEKEKEKEKEKEPDNVDLVSELRAENQRLTASLRELQEGLQQEASRPGAPGSERILLDILEHDWREAQDSRQELCQKLHAVQGELQWAEELRDQYLQEMEDLRLKHRTLQKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTLTSLEGTKALLEVQLQRAQGGTCLKACASSHSLCSNLSSTWSLSEFPSPLGGPEATGEAAVMGGPEPHNSEEATDSEKEINRLSILPFPPSAGSILRRQREEDPAPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDFLNRSLAIRVSGRSPPGGPEPQDKGPDGLSFYGDRWSGAVVRRVLSGPGSARMEPREQRVEAAGLEGACLEAEAQQRTLLWNQGSTLPSLMDSKACQSFHEALEAWAKGPGAEPFYIRANLTLPERADPHALCVKAQEILRLVDSAYKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLPSSRHRGPRSNLKKRALDQLRLVRPKPVGAPAGDSPDQLLLEPCAEPERSLRPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAESLSGEELCPSSAPGAPKAQPATPGLGSRIRAIQESVGKKHCLLELGARGVRELVQNEIYPIVIHVEVTEKNVREVRGLLGRPGWRDSELLRQCRGSEQVLWGLPCSWVQVPAHEWGHAEELAKVVRGRILQEQARLVWVECGSSRGCPSSSEA
uniprot
proteins
disease_involvement
DISEASE: Immunodeficiency 89 and autoimmunity (IMD89) [MIM:619632]: An autosomal recessive disorder characterized by adult onset of recurrent infections, allergies, microcytic anemia, and Crohn disease. {ECO:0000269|PubMed:32238915}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR. {ECO:0000269|PubMed:27991920}.
uniprot
proteins
mass_dalton
115931
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
11259443
uniprot
proteins
pubmed
11356195
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27991920
uniprot
proteins
pubmed
32238915
uniprot
proteins
sequence_length
1032
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins