ITIH4
entrez
3700
canonical
uniprot
Q14624
canonical
ensembl
ENSG00000055955
resolver
ensp
ENSP00000266041
resolver
ensp
ENSP00000384425
resolver
ensp
ENSP00000417824
resolver
ensp
ENSP00000525422
resolver
ensp
ENSP00000525430
resolver
enst
ENST00000485816
resolver
enst
ENST00000855363
resolver
enst
ENST00000855371
resolver
genesymbol
ITIH4
resolver
genesymbol_syn
IHRP
resolver
genesymbol_syn
ITIHL1
resolver
genesymbol_syn
PK120
resolver
hgnc
HGNC:6169
resolver
uniprot
A0ACI8PIV5
resolver
uniprot
B2RMS9
resolver
uniprot
B7Z545
resolver
uniprot
B7ZKJ8
resolver
uniprot
E9PGN5
resolver
uniprot
Q15135
resolver
uniprot
Q9P190
resolver
uniprot
Q9UQ54
resolver
uniprot_entry
A0ACI8PIV5_HUMAN
resolver
uniprot_entry
B2RMS9_HUMAN
resolver
uniprot_entry
B7ZKJ8_HUMAN
resolver
uniprot_entry
ITIH4_HUMAN
resolver
uniprot_sec
B7Z545
resolver
uniprot_sec
E9PGN5
resolver
uniprot_sec
Q15135
resolver
uniprot_sec
Q9P190
resolver
uniprot_sec
Q9UQ54
resolver
amino_acid_sequence
MKPPRPVRTCSKVLVLLSLLAIHQTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIIDGMTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSVSVAPNAKITFELVYEELLKRRLGVYELLLKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNQLVDALTTWQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPEGLTTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQLQDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLTATVSGKLPTQNITFQTESSVAEQEAEFQSPKYIFHNFMERLWAYLTIQQLLEQTVSASDADQQALRNQALNLSLAYSFVTPLTSMVVTKPDDQEQSQVAEKPMEGESRNRNVHSGSTFFKYYLQGAKIPKPEASFSPRRGWNRQAGAAGSRMNFRPGVLSSRQLGLPGPPDVPDHAAYHPFRRLAILPASAPPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEGLRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDYQEGPPGVEISCWSVEL
uniprot
proteins
function
FUNCTION: Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. {ECO:0000269|PubMed:19263524}.
uniprot
proteins
mass_dalton
103357
uniprot
proteins
post_translational_modification
PTM: Cleaved by plasma kallikrein to yield 100 kDa and 35 kDa fragments, and the resulting 100 kDa fragment is further converted to a 70 kDa fragment.; PTM: N- and O-glycosylated. In urine, O-linked glycosylation on threonine residues in the region from Thr-719 to Thr-725 consists of core 1 or possibly core 8 glycans. Mainly Hex(HexNAc)(2), but also some Hex(3)(HexNAc)(3). N-glycosylated but not O-glycosylated in plasma. {ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:7541790}.
uniprot
proteins
protein_family
ITIH family
uniprot
proteins
pubmed
10486281
uniprot
proteins
pubmed
12147176
uniprot
proteins
pubmed
12754519
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14760718
uniprot
proteins
pubmed
16271702
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
19263524
uniprot
proteins
pubmed
21137033
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22171320
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24884609
uniprot
proteins
pubmed
7541790
uniprot
proteins
pubmed
7775381
uniprot
proteins
pubmed
7805892
uniprot
proteins
pubmed
7947966
uniprot
proteins
pubmed
8797089
uniprot
proteins
sequence_length
930
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins