KIF23
entrez
9493
canonical
uniprot
Q02241
canonical
ensembl
ENSG00000137807
resolver
ensp
ENSP00000304978
resolver
ensp
ENSP00000497065
resolver
ensp
ENSP00000504770
resolver
ensp
ENSP00000572352
resolver
ensp
ENSP00000572353
resolver
ensp
ENSP00000572355
resolver
ensp
ENSP00000603248
resolver
ensp
ENSP00000633473
resolver
ensp
ENSP00000746551
resolver
ensp
ENSP00000746555
resolver
enst
ENST00000679126
resolver
genesymbol
KIF23
resolver
genesymbol_syn
KNSL5
resolver
genesymbol_syn
MKLP1
resolver
hgnc
HGNC:6392
resolver
uniprot
A0A7I2V5Y5
resolver
uniprot
B4E1K0
resolver
uniprot
Q8WVP0
resolver
uniprot_entry
A0A7I2V5Y5_HUMAN
resolver
uniprot_entry
KIF23_HUMAN
resolver
uniprot_sec
B4E1K0
resolver
uniprot_sec
Q8WVP0
resolver
amino_acid_sequence
MKSARAKTPRKPTVKKGSQTNLKDPVGVYCRVRPLGFPDQECCIEVINNTTVQLHTPEGYRLNRNGDYKETQYSFKQVFGTHTTQKELFDVVANPLVNDLIHGKNGLLFTYGVTGSGKTHTMTGSPGEGGLLPRCLDMIFNSIGSFQAKRYVFKSNDRNSMDIQCEVDALLERQKREAMPNPKTSSSKRQVDPEFADMITVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVPFDPIKPKPPQSKLLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARPVDKAICGLTPGRRYRNQPRGPVGNEPLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQMMIDEFNKQSNAFKALLQEFDNAVLSKENHMQGKLNEKEKMISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELETQNQKLQRQFSDKRRLEARLQGMVTETTMKWEKECERRVAAKQLEMQNKLWVKDEKLKQLKAIVTEPKTEKPERPSRERDREKVTQRSVSPSPVPLSSNYIAQISNGQQLMSQPQLHRRSNSCSSISVASCISEWEQKIPTYNTPLKVTSIARRRQQEPGQSKTCIVSDRRRGMYWTEGREVVPTFRNEIEIEEDHCGRLLFQPDQNAPPIRLRHRRSRSAGDRWVDHKPASNMQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIETKLIKGDIYKTRGGGQSVQFTDIETLKQESPNGSRKRRSSTVAPAQPDGAESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP
uniprot
proteins
disease_involvement
DISEASE: Anemia, congenital dyserythropoietic, 3A (CDAN3A) [MIM:105600]: An autosomal dominant blood disorder characterized by ineffective erythropoiesis, hemolytic anemia, macrocytosis in the peripheral blood, intravascular hemolysis, and giant multinucleated erythroblasts in the bone marrow. {ECO:0000269|PubMed:23570799, ECO:0000269|PubMed:33159567}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. {ECO:0000269|PubMed:16103226, ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:22522702, ECO:0000269|PubMed:23570799}.
uniprot
proteins
mass_dalton
110059
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated. Deubiquitinated by USP8/UBPY. {ECO:0000269|PubMed:18329369}.
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
11782313
uniprot
proteins
pubmed
1406973
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15197175
uniprot
proteins
pubmed
15297875
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16103226
uniprot
proteins
pubmed
16213214
uniprot
proteins
pubmed
16236794
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18329369
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19468300
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22522702
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23570799
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
25772364
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
33159567
uniprot
proteins
pubmed
36825683
uniprot
proteins
pubmed
41361016
uniprot
proteins
sequence_length
960
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring {ECO:0000269|PubMed:16213214}. Midbody {ECO:0000269|PubMed:36825683}. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.
uniprot
proteins