RNF180
entrez
285671
canonical
uniprot
Q86T96
canonical
ensembl
ENSG00000164197
resolver
ensp
ENSP00000296615
resolver
ensp
ENSP00000373752
resolver
ensp
ENSP00000546221
resolver
ensp
ENSP00000546222
resolver
ensp
ENSP00000546223
resolver
ensp
ENSP00000546226
resolver
ensp
ENSP00000777880
resolver
genesymbol
RNF180
resolver
hgnc
HGNC:27752
resolver
uniprot
Q0JSU3
resolver
uniprot
Q495A8
resolver
uniprot
Q8NBD1
resolver
uniprot_entry
RN180_HUMAN
resolver
uniprot_sec
Q0JSU3
resolver
uniprot_sec
Q495A8
resolver
uniprot_sec
Q8NBD1
resolver
amino_acid_sequence
MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYLENQVIKDKDDSVDAQNICHVWHMNVEALPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRTDYQPTQAGRLMRPSVKYLSHPRVQSGCDKEALLTGGGSENRNHRLLNMARNNNDPGRLTEALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCATRAFHRKSHSLDLNISEKLTLLPTLYEIHSKTTAYSRLNETQPIDLSGLPLQSSKNSYSFQNPSSFDPSMLLQRFSVAPHETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHSANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGLLDHMTLNNEMSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCHHIFCEPCLRTLAKDNPSSTPCPLCRTIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFRRHAAPVTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2. {ECO:0000250|UniProtKB:Q3U827}.
uniprot
proteins
mass_dalton
68254
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
592
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus envelope {ECO:0000250|UniProtKB:Q3U827}.
uniprot
proteins
transmembrane_region
TRANSMEM 565..585; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins