Kif26a
entrez
668303
canonical
uniprot
Q52KG5
canonical
ensembl
ENSMUSG00000021294
resolver
ensp
ENSMUSP00000119482
resolver
enst
ENSMUST00000128402
resolver
genesymbol
Kif26a
resolver
genesymbol_syn
Kiaa1236
resolver
uniprot
C9EF47
resolver
uniprot
Q6PCY3
resolver
uniprot
Q6ZPV4
resolver
uniprot
Q99PT4
resolver
uniprot_entry
KI26A_MOUSE
resolver
uniprot_sec
C9EF47
resolver
uniprot_sec
Q6PCY3
resolver
uniprot_sec
Q6ZPV4
resolver
uniprot_sec
Q99PT4
resolver
amino_acid_sequence
MVGRGASLCAVQPAVAECGPARETPPLEVSPRKRLPAGLDQDPCSSRPAPEGAGASAEQSHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTPLRDPCLSTLLLDKLPASGVQPACRPDTESRCDVCTTHLHQLTREALRLLQTPASHEDPNASRGGLAAPSSRDPPGPVGLMGRQPPVGPDRRKATAWPPGPSVQVSVAPAGLGGALSTVTIQAQQCLEGVWSLSRVNSFLPPTCLAEAAVAAVAVADTVRDCAPAAGPERMSKAWGRGAACTTALVTPAPGTSAGGSTGPSAAASFFIRAAQKLSLASKRKKHHPPPAPSTRGTSTYPTDFSGSLQLWPPPVPPCLLRAASKAKENPSSFGKVKVMLRIWPAQGVQRSAESTSFLKVDSRKKQVTLYDPAAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWLFRLIDERKERLGTRFSIRVSAVEVCGHDQSLRDLLAEVASGSLQDTQSPGVYLREDPVCGTQLQNQNELRAPTAEKAAFYLDAALAARSTSRAGCGEEARRSSHMLFTLHVYQYRVEKCGQGGMSGGRSRLHLIDLGSCDAAVGRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATTNCRTTMIAHISDSPAHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGRARRPPHLRPFHPRAVVLDPDRSAPGLSGDPDYSSSSEQSCDTVIYVGPGGMALSDRELTDNEGPPDFVPIIPALSRRRPSEGPRDADHFRCSTFAELQERLECIDGSEAFPGPQGGSDGAQASPARGGRKPSLPEATPSRKAVAPTVVTSCPRGSPGHDTHRSASDPSKTGTQSEQRVDGSRPEPPASDKTSGGGGRRPLPSPAPPPPRQPEAQGIPKEPGGEGTDSVLRTPPVGMSGQAALPPLLSDSAYLSPSARGRHLERGLLTTTVTLQQPVELNGEDELVFTVVEELPLGGLAGATRPSSLASMSSDCSLQALASGSRPVSIISSINDEFDAYTSQMSEGPGDPGEFPEGTAWAGGSPASSIGSWLSDVGVCLSESRGPTPQPPFSPNSAAGPGPPEFPTPGSSLEESKVRSSECGRPDNPGSARSLHPGEAVATTQTQPGREPWARSPHEVASAQTIHSSLPRKPRTTSTASRARPSRGPYSPGGLFEDPWLLRAEDCDTRQIASTGRAPSPTPGSPRLPETQMMLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPAASCGDAPAEAVVHSGSLKTTSGSKKSVSPKGAFFPRPSGAGPPAPPVRKSSLEQSTALTPTQALGLTRAGAPSAFRGEEEARPSGRSDSSVPKATSSLKARAGKMDVPYRPSGHMSLERCEGLAHGSSKVRDVVGRPPRAVPRLGVPSASPPLGPAPACRNSPAKGVGATKPPAGGAKGRNLGPSTSRALGAPVKPLGPVAGKTAGGAVPGPRAAPRAVPGIGAKAGRGTIMGTKQAFRAAHSRVHELAASGSPSRGGLSWGSTDSDSGNDSGVNLAEERQPSSPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAPDSMSESGTASLGARSRSLKSPKKRATGLQRRRLIPAPLPDAAALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRHRLPLRENEAKPSQDAEKGPVCISSKLRLAERRQQRLQEVQAKRDHLCEELAETQGRLMVEPGRWLEQFEVDPELEPESAEYLVALEQATAALEQCVNLCKAHVMMVTCFDIGVAATTAVPGPQEVDV
uniprot
proteins
function
FUNCTION: Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (PubMed:19914172). Plays a critical role in cerebral cortical development. It probably acts as a microtubule stabilizer that regulates neurite growth and radial migration of cortical excitatory neurons (PubMed:36228617). {ECO:0000269|PubMed:19914172, ECO:0000269|PubMed:36228617}.
uniprot
proteins
mass_dalton
196313
uniprot
proteins
protein_family
KIF26 subfamily
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
11416179
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19914172
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
36228617
uniprot
proteins
sequence_length
1881
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}.
uniprot
proteins