Tas2r4
entrez
57253
canonical
uniprot
Q9JKT3
canonical
ensembl
ENSMUSG00000037140
resolver
ensp
ENSMUSP00000044089
resolver
enst
ENSMUST00000038750
resolver
genesymbol
Tas2r4
resolver
genesymbol_syn
Tas2r108
resolver
genesymbol_syn
Tas2r8
resolver
uniprot
Q53Z44
resolver
uniprot_entry
TA2R4_MOUSE
resolver
uniprot_sec
Q53Z44
resolver
amino_acid_sequence
MLWELYVFVFAASVFLNFVGIIANLFIIVIIIKTWVNSRRIASPDRILFSLAITRFLTLGLFLLNSVYIATNTGRSVYFSTFFLLCWKFLDANSLWLVTILNSLYCVKITNFQHPVFLLLKRTISMKTTSLLLACLLISALTTLLYYMLSQISRFPEHIIGRNDTSFDLSDGILTLVASLVLNSLLQFMLNVTFASLLIHSLRRHIQKMQRNRTSFWNPQTEAHMGAMRLMICFLVLYIPYSIATLLYLPSYMRKNLRAQAICMIITAAYPPGHSVLLIITHHKLKAKAKKIFCFYK
uniprot
proteins
function
FUNCTION: Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
34202
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
10761934
uniprot
proteins
pubmed
10761935
uniprot
proteins
pubmed
11696554
uniprot
proteins
pubmed
12139982
uniprot
proteins
pubmed
12581520
uniprot
proteins
pubmed
14627538
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15886333
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 12..32; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 47..67; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 81..101; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 129..149; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 172..192; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins