ATP5ME
entrez
521
canonical
uniprot
P56385
canonical
ensembl
ENSG00000169020
resolver
ensp
ENSP00000306003
resolver
enst
ENST00000304312
resolver
genesymbol
ATP5ME
resolver
genesymbol_syn
ATP5I
resolver
genesymbol_syn
ATP5K
resolver
hgnc
HGNC:846
resolver
uniprot
Q0D2L9
resolver
uniprot_entry
ATP5I_HUMAN
resolver
uniprot_sec
Q0D2L9
resolver
amino_acid_sequence
MVPPVQVSPLIKLGRYSALFLGVAYGATRYNYLKPRAEEERRIAAEEKKKQDELKRIARELAEDDSILK
uniprot
proteins
function
FUNCTION: Subunit e, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (PubMed:37244256). {ECO:0000250|UniProtKB:P19483, ECO:0000269|PubMed:37244256, ECO:0000305|PubMed:37244256}.
uniprot
proteins
mass_dalton
7933
uniprot
proteins
protein_family
ATPase e subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19892738
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
37244256
uniprot
proteins
sequence_length
69
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion. Mitochondrion inner membrane.
uniprot
proteins