Cep350
entrez
74081
canonical
uniprot
E9Q309
canonical
ensembl
ENSMUSG00000033671
resolver
ensp
ENSMUSP00000120085
resolver
enst
ENSMUST00000138762
resolver
genesymbol
Cep350
resolver
genesymbol_syn
Kiaa0480
resolver
uniprot
A0A1D5RMJ4
resolver
uniprot
D3YTP2
resolver
uniprot
Q6A062
resolver
uniprot
Q8BXM7
resolver
uniprot_entry
CE350_MOUSE
resolver
uniprot_sec
A0A1D5RMJ4
resolver
uniprot_sec
D3YTP2
resolver
uniprot_sec
Q6A062
resolver
uniprot_sec
Q8BXM7
resolver
amino_acid_sequence
MRSSKSKEVPLPNPRNSQSKETIQDVTTSWDALSQTKAALRHIENKLEVTPTSTAVIDSVMDTKKSASATRKISRKDGRCLDDSWASAPTSKFSKPRKEKSRSPLRATTLESNVKKNNRVEFREPLVSYRETHGTPFSLSPSHLESKHVYCIHEEKPESGKQMVVSREDRNIQCCDFESAQPSVISDTVVRFLNDGPAIDALHSSECLMKMGVHVRTEDEMPNRTKGSENNSKPSLNNMEHDVDPKVMLLSDSSPSSSACNSQRSDISKRQQHDIKLEKLKERIRKQWEHSEEINGQAQTLGHIDHPVMVVNVDNSVTTKVRKVATAPPAPAYKGFNPSETKIRTPDGKVWQEAEFQSMSRELYRDLALQFTDDTSVKEKPVEKSKEKKVVKPVRKIQKVTQLSNPECKTGSSRLISTSSWRDGQKLVKKILGPAPKMEQKERRPTSNDRSGRERVAKFGGHIGRAESDPKLDVSHKQLPRSSARSRSSRAWSETNIVKSALSLPDNKQEESAALNKDFLPVEIRGILDDLQLDSSAQAVRQEAGEGQNQKSSAPEQVPRSHSPVKRKPDKITANEDPPVISKKRHYDTDEVRQYIVRQQEERRRRQHEEKKAQKEATEQKNKRLQELYRRQREAFSKAKTVPPSDPLVSRRLQETYSKLLLEKTLLEEPARQHVTQDIQARPGYQPSGESDKENKIQERPPSASSSSDLSLSEPPQPLARRDLMEPTWMQPDRLSPRVHSSQAQPLAGTTENLLSHLLHLEHVGILHKDYESVLPAKKSHNTASGPLTFTPQPYLTSQAPHPDALLKPSTSQYKTKLDRIEALKATAASLSSRIESEAKKLAGASINYGSVWNTECDVKLAPQENGPWTKAISPPVKEDIEDAFSARIQKMLGTCVSHAAFDDELPGVGSLSEYKKLPEMIRPQSAISSLRMKSPSPKPGGLLAQLCRRQTDSSSSDIQACSQERAKRSLCSSIDSVSEGPLLSEGSLSEEEERRDARPLLKVAEILKEKEFCAGERNSYEPIKEFQKEAEKFLPLFGHIGGTQSKGPWEELAKGSPHSVINIFTKSYQLYGKGFEDRGTLVSRPLNATATPLSSVSYEDDFVSSPGSGTLTERKSTLESQVDGSSLGVQEEHLSRQFACDLASVDATSQHSSGARSAGSTRSSSASKGKKGKKDKMDWLDSLTGSAQNPLIDEEKVQSDSERGSHPSRKLGTGSKLAVGDSEQTLDAESTLEDLSGHSVSGSSDKGRSQKTPTSPLSPSSQKLLQFDLPGTSLERSKSSVIVPPTTTGFKPTAAFTDVNKTEMASAPGPQRFSPAGLQHRMAAELSYLSALEESVRQLSDVERVRGIALAQQESVSLAQIIKAQQQRHERDLALLKLKAEQEALECQRQLEETRNKTAQVHAESLQQVVKSQREVTEVLQEATCKIAAQQSETARLTTDAARQICEMAELTRTHLADAITTSGVPLATLYDHQRQHFPDFMRKLRTKAETDRISHSASHSQSKEGAVDSKRQKFSPSRDSYSESSRYKSHDYRSSGSSRQDSPSVPPSKENEKPFHGEKMESSVDEQLQTAADDSLRSDSIPSLPDEKDSTSIATEYSLKFDESMTEDEIEEKSFRSLLPSESHRRFNMEKKRGHHDDSDEDASPDKTALSSTKELSMPFSGGQDSFSKFTMEMVRQYMKEEEVRAAHQSSLLRLREKALKEKTKAELAWLEHQKKHLRDKGEDDKMPPLRKKQRGLLLRLQQEKAEIKRLQEANKAARKERQLILKQQEEIERIRQTTIKLQEKLKSAGEKKLGSLADDDEAEDNKAASPGPPGLETRSPSPISISSSETSSIMQKLKSMRSRMDEKFLTKREQKLMQRRQHAEELLEWKRRLDAEEAEIQQMEKQALAAWDKELVKPRTPKKEQESQRTEQKGIASEEGSPMPSYSPRNSESCIPEDLGSPSDLCVPSEARVQAQPGSPEHSTLTEEMVFSQELESTSPSKHSPPKSCLSMSKQESSKASHRTEGHCHLPVKSHQPCYSWSDESLSMTQSETTSDQSDIEGRIRALKDELRKRKSVVEQLKREQRKRQKERLKAQEASLLRQLETYDEFIKKTEGELSQDLDISPTSKFQMKTLSSVSEKPKIKPHPLHRSETAKTWKSVTESERSRGSLASIAEHVDSSLSCSERAISERSLSAYAKRGVELDSRIEHLQASSPDLSSRKAQTESRDSLESAPSLSPVKELNAPDRIYDVSEAKAEDTSQKSEIQEIESMKLESSEVEDACCKQSGGSEVLLKLDLASETLSSKELPSDSANVQQDLDKPATETSHEKEEALKEDQSNHSTDDRSPDIQSAGGIPEQGCRESGDSTCSGQLSVPKESSYSEDFEVSSFRKGISADEISKDDSEGSSPSSLRKDSQSHRDRSQLTRSSRSRATGSGSDEEISECLGEKSLSVHSGVHSERLLELRSPTELMKSKERSDVGHEQGGTEPLPLAATEELLDFHIGDRVLIGSVQPGTLRFKGETDFAKGFWAGVELDKPEGNNNGTYDGIVYFVCKDKHGIFAPPQKISHLLENFDDTDINEDEESYSDEQYQPYNQEQKDIKCLKDRENNIAEYFCEKSLPSMHNTDASVDKDRSLNIETDTSEVLEVHGHQQPSVDPLISYKENKVLVSDATESVPAAAGAATSDNTFSGESKQQQLAEKEENFYSQVLEKPSTPLLDLLTREKNQLEAQLKSSISEEKKSKQQLETVSLLTDSLLQVFVKDTVSQLQQVKKARNEKIQLSNQEFLDQKKVPPQDLPQNTEEQSPSVPSCFLRSELEDEKEEISSPDMCPRPESPVFGASGQEELAKRLAELEISREFLSALDDQDWFDEDFGLSSSHKIQKNKAEETIVPLMAEPKRAPQKPCETLLAVPHTAEEVESLVHNAAEELWKWKELGQDLHGLSLPTTFLGGASKGLDIGSTSRRVYKQAVFDLTKEIFEEIFAEDPNVNQPVWMKPCRINSSYFRRVKNPNNLDEIKHFITTEVLKLLSLKKEPNHKTDWQKMMKFGRKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIFETLIKDTIDVLNQISEKQGRMLLV
uniprot
proteins
function
FUNCTION: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CPAP. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation. {ECO:0000250|UniProtKB:Q5VT06}.
uniprot
proteins
mass_dalton
346456
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis. {ECO:0000250|UniProtKB:Q5VT06}.
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27965440
uniprot
proteins
sequence_length
3095
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q5VT06}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q5VT06}. Nucleus {ECO:0000250|UniProtKB:Q5VT06}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q5VT06}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q5VT06}. Note=Associated with mitotic spindles. Nuclear, in discrete foci. Associated with intermediate filaments. Also present in the pericentrosomal area. Localizes on both mother and daughter centrioles. Localizes to an axial position on the mother centriole. Localizes to the distal end of the centriole on the subdistal appendage region. {ECO:0000250|UniProtKB:Q5VT06}.
uniprot
proteins