PRKACG
entrez
5568
canonical
uniprot
P22612
canonical
ensembl
ENSG00000165059
resolver
ensp
ENSP00000366488
resolver
enst
ENST00000377276
resolver
genesymbol
PRKACG
resolver
hgnc
HGNC:9382
resolver
uniprot
O60850
resolver
uniprot
Q5VZ02
resolver
uniprot
Q86YI1
resolver
uniprot_entry
KAPCG_HUMAN
resolver
uniprot_sec
O60850
resolver
uniprot_sec
Q5VZ02
resolver
uniprot_sec
Q86YI1
resolver
activity_regulation
ACTIVITY REGULATION: Activated by cAMP.
uniprot
proteins
amino_acid_sequence
MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
uniprot
proteins
disease_involvement
DISEASE: Bleeding disorder, platelet-type, 19 (BDPLT19) [MIM:616176]: A disorder characterized by increased bleeding tendency due to platelet dysfunction. Clinical features include epistaxis, hematomas, bleeding after tooth extraction, and menorrhagia. {ECO:0000269|PubMed:25061177}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
2.7.11.11
uniprot
proteins
function
FUNCTION: Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
uniprot
proteins
mass_dalton
40434
uniprot
proteins
protein_family
AGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
cAMP subfamily
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
2342480
uniprot
proteins
pubmed
25061177
uniprot
proteins
pubmed
9598317
uniprot
proteins
sequence_length
351
uniprot
proteins