Tmx2
entrez
66958
canonical
uniprot
Q9D710
canonical
ensembl
ENSMUSG00000050043
resolver
ensp
ENSMUSP00000059582
resolver
ensp
ENSMUSP00000107293
resolver
ensp
ENSMUSP00000107294
resolver
enst
ENSMUST00000053664
resolver
enst
ENSMUST00000111664
resolver
enst
ENSMUST00000111665
resolver
genesymbol
Tmx2
resolver
genesymbol_syn
Txndc14
resolver
uniprot
D3Z2J6
resolver
uniprot
Q8BW13
resolver
uniprot_entry
D3Z2J6_MOUSE
resolver
uniprot_entry
TMX2_MOUSE
resolver
uniprot_sec
Q8BW13
resolver
amino_acid_sequence
MAVLAPLIALVYSVPRLSRWLARPYCLLSALLSIAFLLVRKLPPICNGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLTRQLPTLILFQGGKEVIRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKHSKGGDMSEEKPVDPAPTTVPDGENKKDK
uniprot
proteins
function
FUNCTION: Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain. {ECO:0000250|UniProtKB:Q9Y320}.
uniprot
proteins
mass_dalton
33943
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
295
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Y320}; Single-pass type I membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q9Y320}; Single-pass type I membrane protein {ECO:0000255}. Note=Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria. {ECO:0000250|UniProtKB:Q9Y320}.
uniprot
proteins
transmembrane_region
TRANSMEM 103..125; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins