Il1f10
entrez
215274
canonical
uniprot
Q8R459
canonical
ensembl
ENSMUSG00000046845
resolver
ensp
ENSMUSP00000063004
resolver
enst
ENSMUST00000058056
resolver
genesymbol
Il1f10
resolver
uniprot
Q3KNF2
resolver
uniprot_entry
IL1FA_MOUSE
resolver
uniprot_entry
Q3KNF2_MOUSE
resolver
amino_acid_sequence
MCSLPMARYYIIKDAHQKALYTRNGQLLLGDPDSDNYSPEKVCILPNRGLDRSKVPIFLGMQGGSCCLACVKTREGPLLQLEDVNIEDLYKGGEQTTRFTFFQRSLGSAFRLEAAACPGWFLCGPAEPQQPVQLTKESEPSTHTEFYFEMSR
uniprot
proteins
function
FUNCTION: Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
17078
uniprot
proteins
protein_family
IL-1 family
uniprot
proteins
pubmed
11991723
uniprot
proteins
sequence_length
152
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8WWZ1}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250|UniProtKB:Q8WWZ1}. Secreted {ECO:0000250|UniProtKB:Q8WWZ1}. Note=The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. {ECO:0000250|UniProtKB:Q8WWZ1}.
uniprot
proteins