Crym
entrez
117024
canonical
uniprot
Q9QYU4
canonical
ensembl
ENSRNOG00000061215
resolver
ensembl
ENSRNOG00055007180
resolver
ensembl
ENSRNOG00060020924
resolver
ensembl
ENSRNOG00065030922
resolver
ensp
ENSRNOP00000073313
resolver
ensp
ENSRNOP00055009414
resolver
ensp
ENSRNOP00060029865
resolver
ensp
ENSRNOP00065043795
resolver
enst
ENSRNOT00000088482
resolver
enst
ENSRNOT00055011904
resolver
enst
ENSRNOT00060036299
resolver
enst
ENSRNOT00065053301
resolver
genesymbol
Crym
resolver
uniprot_entry
CRYM_RAT
resolver
amino_acid_sequence
MRRAPAFLSADEVQDHLRSSSLLIPPLEAALANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEGHSNNAVPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIATKFLKPPGSDVLCILGAGVQAYSHYEIFTEQFSFKEVRMWNRTRENAEKFASSVQGDVRVCSSVQEAVTGADVIITVTMATEPILFGEWVKPGAHINAVGASRPDWRELDDELMKQAVLYVDSREAALKESGDVLLSGADIFAELGEVVSGAKPAYCEKTTVFKSLGMAVEDLVAAKLVYDSWSSGK
uniprot
proteins
ec_number
1.5.1.1
uniprot
proteins
ec_number
1.5.1.25
uniprot
proteins
function
FUNCTION: Catalyzes the NAD(P)H-dependent reduction of imine double bonds of a number of cyclic ketimine substrates, including sulfur-containing cyclic ketimines. Under physiological conditions, it efficiently catalyzes delta(1)-piperideine-2-carboxylate (P2C) and delta(1)-pyrroline-2-carboxylate (Pyr2C) reduction, suggesting a central role in lysine and glutamate metabolism. Additional substrates are delta(2)-thiazoline-2-carboxylate (T2C), 3,4-dehydrothiomorpholine-3-carboxylate (AECK), and (R)-lanthionine ketimine (LK) that is reduced at very low rate compared to other substrates (By similarity). Also catalyzes the NAD(P)H-dependent reduction of (S)-cystathionine ketimine (CysK) (By similarity). {ECO:0000250|UniProtKB:Q14894, ECO:0000250|UniProtKB:Q2KHX6}.
uniprot
proteins
mass_dalton
33554
uniprot
proteins
protein_family
Ornithine cyclodeaminase/mu-crystallin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
313
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q14894}.
uniprot
proteins