Il22ra2
entrez
237310
canonical
uniprot
Q80XF5
canonical
ensembl
ENSMUSG00000039760
resolver
ensp
ENSMUSP00000042642
resolver
enst
ENSMUST00000036564
resolver
genesymbol
Il22ra2
resolver
uniprot
Q3UU14
resolver
uniprot
Q7TNI5
resolver
uniprot_entry
I22R2_MOUSE
resolver
uniprot_sec
Q3UU14
resolver
uniprot_sec
Q7TNI5
resolver
amino_acid_sequence
MMPKHCLLGLLIILLSSATEIQPARVSLTPQKVRFQSRNFHNILHWQAGSSLPSNNSIYFVQYKMYGQSQWEDKVDCWGTTALFCDLTNETLDPYELYYGRVMTACAGRHSAWTRTPRFTPWWETKLDPPVVTITRVNASLRVLLRPPELPNRNQSGKNASMETYYGLVYRVFTINNSLEKEQKAYEGTQRAVEIEGLIPHSSYCVVAEMYQPMFDRRSPRSKERCVHIP
uniprot
proteins
function
FUNCTION: Receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. {ECO:0000269|PubMed:12700595}.
uniprot
proteins
mass_dalton
26613
uniprot
proteins
mutagenesis
MUTAGEN 66; /note="Y->A: Abolishes IL22-binding."; /evidence="ECO:0000269|PubMed:19285080"; MUTAGEN 118; /note="R->A: Abolishes IL22-binding."; /evidence="ECO:0000269|PubMed:19285080
uniprot
proteins
protein_family
Type II cytokine receptor family
uniprot
proteins
pubmed
12700595
uniprot
proteins
pubmed
15201862
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19285080
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
230
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12700595}.
uniprot
proteins