Gpx2
entrez
14776
canonical
uniprot
Q9JHC0
canonical
ensembl
ENSMUSG00000042808
resolver
ensp
ENSMUSP00000081012
resolver
genesymbol
Gpx2
resolver
uniprot
Q3V2B2
resolver
uniprot_entry
GPX2_MOUSE
resolver
uniprot_sec
Q3V2B2
resolver
amino_acid_sequence
MAYIAKSFYDLSAIGLDGEKIDFNTFRGRAVLIENVASLUGTTTRDYNQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFSLTQKCDVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVSWNFEKFLIGPEGEPFRRYSRSFQTINIEPDIKRLLKVAI
uniprot
proteins
ec_number
1.11.1.12
uniprot
proteins
ec_number
1.11.1.9
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide. {ECO:0000250|UniProtKB:P18283}.
uniprot
proteins
mass_dalton
21990
uniprot
proteins
protein_family
Glutathione peroxidase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
8661011
uniprot
proteins
sequence_length
190
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P18283}.
uniprot
proteins