Abhd17a
entrez
216169
canonical
uniprot
Q99JW1
canonical
ensembl
ENSMUSG00000003346
resolver
ensp
ENSMUSP00000003436
resolver
ensp
ENSMUSP00000188911
resolver
ensp
ENSMUSP00000188922
resolver
genesymbol
Abhd17a
resolver
genesymbol_syn
D10Bwg1364e
resolver
uniprot
Q5DU54
resolver
uniprot_entry
AB17A_MOUSE
resolver
uniprot_sec
Q5DU54
resolver
amino_acid_sequence
MNGLSVSELCCLFCCPPCPGRIAAKLAFLPPDPTYSLVPEPEPGPGGAGAAPSGPLRTSAATPGRWKIHLTERADFQYGQRELDTIEVFVTKSARANRIACMYVRCVPGARYTVLFSHGNAVDLGQMCSFYVGLGTRIGCNIFSYDYSGYGISSGRPSEKNLYADIDAAWQALRTRYGISPDSIILYGQSIGTVPTVDLASRYECAAVVLHSPLTSGMRVAFPDTKKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALYERCPKAVEPLWVEGAGHNDIELYSQYLERLRRFISQELPSQRA
uniprot
proteins
ec_number
3.1.2.22
uniprot
proteins
function
FUNCTION: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS. Has depalmitoylating activity towards DLG4/PSD95. May have depalmitoylating activity towars MAP6. {ECO:0000250|UniProtKB:Q5XIJ5, ECO:0000250|UniProtKB:Q96GS6}.
uniprot
proteins
mass_dalton
33950
uniprot
proteins
post_translational_modification
PTM: Palmitoylated on cysteine residues located in a cysteine cluster at the N-terminus which promotes membrane localization. Palmitoylation is required for post-synaptic localization and for depalmitoylating activity towards DLG4/PSD95. {ECO:0000250|UniProtKB:Q7M759}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
ABHD17 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
310
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q96GS6}; Lipid-anchor {ECO:0000250|UniProtKB:Q96GS6}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96GS6}. Endosome membrane {ECO:0000250|UniProtKB:Q96GS6}; Lipid-anchor {ECO:0000250|UniProtKB:Q96GS6}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96GS6}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q5XIJ5}. Postsynaptic density membrane {ECO:0000250|UniProtKB:Q5XIJ5}.
uniprot
proteins