Rbbp9
entrez
29459
canonical
uniprot
O88350
canonical
ensembl
ENSRNOG00000007972
resolver
ensembl
ENSRNOG00055001668
resolver
ensembl
ENSRNOG00055024382
resolver
ensembl
ENSRNOG00060001699
resolver
ensembl
ENSRNOG00065028517
resolver
ensp
ENSRNOP00000010678
resolver
ensp
ENSRNOP00055002002
resolver
ensp
ENSRNOP00055034144
resolver
ensp
ENSRNOP00060001710
resolver
ensp
ENSRNOP00065040325
resolver
enst
ENSRNOT00055002681
resolver
enst
ENSRNOT00055041907
resolver
enst
ENSRNOT00060002604
resolver
enst
ENSRNOT00065049175
resolver
genesymbol
Rbbp9
resolver
genesymbol_syn
Bog
resolver
uniprot
Q3T1H7
resolver
uniprot_entry
RBBP9_RAT
resolver
uniprot_sec
Q3T1H7
resolver
amino_acid_sequence
MASPTKAVIVPGNGGGDVATHGWYGWVRKGLEQIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHQVYALILVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIIQFGSTDDPFLPWKEQQEVADRLDAKLYKFTDRGHFQNTEFHELIRVVKSMLTPAL
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Serine hydrolase. Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir (By similarity). May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation (By similarity). May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 (PubMed:9697699). {ECO:0000250|UniProtKB:O75884, ECO:0000269|PubMed:9697699}.
uniprot
proteins
mass_dalton
20995
uniprot
proteins
mutagenesis
MUTAGEN 63; /note="L->Q: Loss of binding to RB1 binding."; /evidence="ECO:0000269|PubMed:9697699
uniprot
proteins
protein_family
RBBP9 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9697699
uniprot
proteins
sequence_length
186
uniprot
proteins