ARHGAP9
entrez
64333
canonical
uniprot
Q9BRR9
canonical
ensembl
ENSG00000123329
resolver
ensp
ENSP00000377380
resolver
ensp
ENSP00000377386
resolver
ensp
ENSP00000394307
resolver
ensp
ENSP00000397950
resolver
ensp
ENSP00000473445
resolver
ensp
ENSP00000576831
resolver
ensp
ENSP00000576832
resolver
ensp
ENSP00000576833
resolver
ensp
ENSP00000576834
resolver
ensp
ENSP00000657924
resolver
ensp
ENSP00000679683
resolver
genesymbol
ARHGAP9
resolver
hgnc
HGNC:14130
resolver
uniprot
B3KQ74
resolver
uniprot
B4DVI3
resolver
uniprot
E9PDX9
resolver
uniprot
Q8NAF3
resolver
uniprot
Q8TCJ3
resolver
uniprot
Q8WYR0
resolver
uniprot
Q96EZ2
resolver
uniprot
Q96S74
resolver
uniprot_entry
B3KQ74_HUMAN
resolver
uniprot_entry
RHG09_HUMAN
resolver
uniprot_sec
B4DVI3
resolver
uniprot_sec
E9PDX9
resolver
uniprot_sec
Q8NAF3
resolver
uniprot_sec
Q8TCJ3
resolver
uniprot_sec
Q8WYR0
resolver
uniprot_sec
Q96EZ2
resolver
uniprot_sec
Q96S74
resolver
amino_acid_sequence
MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
uniprot
proteins
function
FUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate. {ECO:0000269|PubMed:11396949}.
uniprot
proteins
mass_dalton
83260
uniprot
proteins
mutagenesis
MUTAGEN 343; /note="K->A: Strongly reduced affinity for phosphoinositides."; /evidence="ECO:0000269|PubMed:17339315"; MUTAGEN 399; /note="R->A: Reduced affinity for phosphoinositides."; /evidence="ECO:0000269|PubMed:17339315
uniprot
proteins
pubmed
11396949
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
17339315
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
19807924
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
750
uniprot
proteins