Bphl
entrez
68021
canonical
uniprot
Q8R164
canonical
ensembl
ENSMUSG00000038286
resolver
ensp
ENSMUSP00000046168
resolver
ensp
ENSMUSP00000163526
resolver
ensp
ENSMUSP00000163532
resolver
enst
ENSMUST00000040656
resolver
genesymbol
Bphl
resolver
uniprot
Q8BVH2
resolver
uniprot
Q8R589
resolver
uniprot
Q9DCC6
resolver
uniprot_entry
BPHL_MOUSE
resolver
uniprot_sec
Q8BVH2
resolver
uniprot_sec
Q8R589
resolver
uniprot_sec
Q9DCC6
resolver
amino_acid_sequence
MATATVRPAAQRLRLLLSPLKSRICVPQAEPVATFGTAVTSAKVAVNGVHLHYQRVGEGEHAILLLPGMLGSGKTDFAPQLQSLNKKRFTLVAWDPRGYGYSRPPDRDFPRDFFERDAKDAVDLMKALQFKQVSLLGWSDGGITALIAAAKYPSYIRKMVIWGANAYVTEEDSRIYQGIRDVSKWSEKARKPLEALYGYDYLAKTCEDWVDGISQFKQLPEGNICRHLLPLVQCPTLIVHGEKDPLVPRFHADFLLQHVKGSRLHLMPEGKHNLHLRFADEFNRLVEDFLQ
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Specific alpha-amino acid ester serine hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. Has homocysteine-thiolactonase activity (in vitro) and may play a significant role in the detoxification of homocysteine thiolactone in vivo. Catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir, converting them into their active forms (acyclovir and ganciclovir). {ECO:0000250|UniProtKB:Q86WA6}.
uniprot
proteins
mass_dalton
32851
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
Lipase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
30121252
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q86WA6}.
uniprot
proteins