Gar1
entrez
68147
canonical
uniprot
Q9CY66
canonical
ensembl
ENSMUSG00000028010
resolver
ensp
ENSMUSP00000029643
resolver
ensp
ENSMUSP00000199029
resolver
genesymbol
Gar1
resolver
genesymbol_syn
Nola1
resolver
uniprot
Q80X93
resolver
uniprot
Q8C6C5
resolver
uniprot
Q8VDH0
resolver
uniprot_entry
GAR1_MOUSE
resolver
uniprot_sec
Q80X93
resolver
uniprot_sec
Q8C6C5
resolver
uniprot_sec
Q8VDH0
resolver
amino_acid_sequence
MSFRGGGRGGFNRGGGGGGFNRGGGSNNHFRGGGGGGGGSFRGGGGGGGGSFRGGGRGGFGRGGGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQVGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGFRGGRGGGGFRGRGH
uniprot
proteins
function
FUNCTION: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
23474
uniprot
proteins
protein_family
GAR1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
231
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. Nucleus, Cajal body {ECO:0000250}. Note=Also localized to Cajal bodies (coiled bodies). {ECO:0000250}.
uniprot
proteins