Calhm4
entrez
270711
canonical
uniprot
Q8CE93
canonical
ensembl
ENSMUSG00000039508
resolver
ensp
ENSMUSP00000042466
resolver
enst
ENSMUST00000048052
resolver
genesymbol
Calhm4
resolver
genesymbol_syn
Fam26d
resolver
uniprot_entry
CAHM4_MOUSE
resolver
amino_acid_sequence
MSPDLNCISSSLLRSEPCINSLIAILTVCGQQLFSSYTFSCPCQVGKNFYYGSAFLVVPALILLIAGYALRGQMWTVASEYCCCSCTPPYRRSSPLERRLACLMFFDITGRALVAPLTWLTVTLLTGTYYECAASEFASVDQYPMFANVTPSKREEMLAGFPCYTSAPSDVIPIRDEVALLHRYQSQMLGWILVVLATIALLLSKCLARCCSPLTSLQHHYWTNHLHNERVLFEKAAEEHSQLLIRHRIKKVFGFVPGSEDIKHIRIPSCQDWREISVPNLLCVGDTSQGPYSFLGDRVVEENEEDRQEGIEMKP
uniprot
proteins
function
FUNCTION: May assemble to form gap junction channel-like structures involved in intercellular communication. Channel gating and ion conductance are likely regulated by membrane lipids rather than by membrane depolarization or extracellular calcium levels. {ECO:0000250|UniProtKB:Q5JW98}.
uniprot
proteins
mass_dalton
35429
uniprot
proteins
protein_family
CALHM family
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
315
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5JW98}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 15..37; /note="Helical; Name=S1"; /evidence="ECO:0000250|UniProtKB:Q5JW98"; TRANSMEM 49..71; /note="Helical; Name=S2"; /evidence="ECO:0000250|UniProtKB:Q5JW98"; TRANSMEM 105..130; /note="Helical; Name=S3"; /evidence="ECO:0000250|UniProtKB:Q5JW98"; TRANSMEM 185..208; /note="Helical; Name=S4"; /evidence="ECO:0000250|UniProtKB:Q5JW98
uniprot
proteins