CBLN4
entrez
140689
canonical
uniprot
Q9NTU7
canonical
ensembl
ENSG00000054803
resolver
ensp
ENSP00000064571
resolver
enst
ENST00000064571
resolver
genesymbol
CBLN4
resolver
genesymbol_syn
CBLNL1
resolver
hgnc
HGNC:16231
resolver
uniprot
A8K0S5
resolver
uniprot_entry
CBLN4_HUMAN
resolver
uniprot_sec
A8K0S5
resolver
amino_acid_sequence
MGSGRRALSAVPAVLLVLTLPGLPVWAQNDTEPIVLEGKCLVVCDSNPATDSKGSSSSPLGISVRAANSKVAFSAVRSTNHEPSEMSNKTRIIYFDQILVNVGNFFTLESVFVAPRKGIYSFSFHVIKVYQSQTIQVNLMLNGKPVISAFAGDKDVTREAATNGVLLYLDKEDKVYLKLEKGNLVGGWQYSTFSGFLVFPL
uniprot
proteins
function
FUNCTION: Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity). Essential for the formation and maintenance of inhibitory GABAergic synapses (By similarity). Promotes the development of dendrite-targeting inhibitory GABAergic synapses made by somatostatin-positive interneurons (By similarity). May contribute to the function of ventral medial habenula region of the brain implicated in the regulation of anxiety-related behaviors (By similarity). May play a role in CBLN3 export from the endoplasmic reticulum and secretion (By similarity). {ECO:0000250|UniProtKB:Q8BME9}.
uniprot
proteins
mass_dalton
21808
uniprot
proteins
post_translational_modification
PTM: Sialoglycoprotein. {ECO:0000250|UniProtKB:Q8BME9}.
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
201
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8BME9}. Synapse {ECO:0000250|UniProtKB:Q8BME9}. Note=Detected at GABAergic synapses. {ECO:0000250|UniProtKB:Q8BME9}.
uniprot
proteins