Rabep1
entrez
54190
canonical
uniprot
O35550
canonical
ensembl
ENSRNOG00000005015
resolver
ensp
ENSRNOP00000090309
resolver
ensp
ENSRNOP00000093398
resolver
ensp
ENSRNOP00000100373
resolver
ensp
ENSRNOP00000104261
resolver
enst
ENSRNOT00000107871
resolver
enst
ENSRNOT00000128672
resolver
enst
ENSRNOT00000137271
resolver
genesymbol
Rabep1
resolver
genesymbol_syn
Rabpt5
resolver
genesymbol_syn
Rabpt5a
resolver
uniprot
A0A8I6AFR7
resolver
uniprot
A0ABK0LFP3
resolver
uniprot
A0ABK0LFW1
resolver
uniprot
P70609
resolver
uniprot_entry
A0A8I6AFR7_RAT
resolver
uniprot_entry
A0ABK0LFP3_RAT
resolver
uniprot_entry
A0ABK0LFW1_RAT
resolver
uniprot_entry
RABE1_RAT
resolver
uniprot_sec
P70609
resolver
amino_acid_sequence
MAQPGPAPQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRAKFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERAQWAQYRESADREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKGKDNKKIDTEEEVKIPVVCALTQEESSTPLSNEEEHLDSTHGSVHSLDADLLLPSGDPFSKSDNDMFKEGLRRAQSTDSLGTSSSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFDTVSLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLRQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVQVLRELVLKYRENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEIKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLPET
uniprot
proteins
function
FUNCTION: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Forms a complex with RABGEF1 that stimulates RABGEF1-mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium. {ECO:0000250|UniProtKB:O35551, ECO:0000250|UniProtKB:Q15276}.
uniprot
proteins
mass_dalton
99428
uniprot
proteins
post_translational_modification
PTM: Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity. {ECO:0000250}.
uniprot
proteins
protein_family
Rabaptin family
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
22841712
uniprot
proteins
sequence_length
862
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Recycling endosome {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}.
uniprot
proteins