Krt19
entrez
16669
canonical
uniprot
P19001
canonical
ensembl
ENSMUSG00000020911
resolver
ensp
ENSMUSP00000007317
resolver
enst
ENSMUST00000007317
resolver
genesymbol
Krt19
resolver
genesymbol_syn
Krt1-19
resolver
uniprot
B1AQ78
resolver
uniprot_entry
B1AQ78_MOUSE
resolver
uniprot_entry
K1C19_MOUSE
resolver
amino_acid_sequence
MTSYSYRQTSAMSSFGGTGGGSVRIGSGGVFRAPSIHGGSGGRGVSVSSTRFVTSSSGSYGGVRGGSFSGTLAVSDGLLSGNEKITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKQGPGPSRDYNHYFKTIEDLRDKILGATIDNSKIVLQIDNARLAADDFRTKFETEHALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEEEITALRSQVGGQVSVEVDSTPGVDLAKILSEMRSQYEIMAEKNRKDAEATYLARIEELNTQVAVHSEQIQISKTEVTDLRRTLQGLEIELQSQLSMKAALEGTLAETEARYGVQLSQIQSVISGFEAQLSDVRADIERQNQEYKQLMDIKSRLEQEIATYRSLLEGQEAHYNNLPTPKAI
uniprot
proteins
function
FUNCTION: Structural component of intermediate filaments in epithelial cells. Forms intermediate filaments by heterodimerizing with the type II keratin KRT8, providing mechanical integrity to epithelial cells (By similarity). Integrates into the intermediate filament network of skeletal muscle fibers alongside desmin and KRT18, contributing to force transmission (PubMed:31721615). Specifically interacts with the actin-binding domain of dystrophin, helping to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity). {ECO:0000250|UniProtKB:P08727, ECO:0000269|PubMed:31721615}.; FUNCTION: Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
44542
uniprot
proteins
protein_family
Intermediate filament family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1701153
uniprot
proteins
pubmed
21049038
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
2479589
uniprot
proteins
pubmed
2483396
uniprot
proteins
pubmed
31721615
uniprot
proteins
sequence_length
403
uniprot
proteins