Eif2d
entrez
16865
canonical
uniprot
Q61211
canonical
ensembl
ENSMUSG00000026427
resolver
ensp
ENSMUSP00000063894
resolver
ensp
ENSMUSP00000108065
resolver
ensp
ENSMUSP00000137678
resolver
ensp
ENSMUSP00000138061
resolver
ensp
ENSMUSP00000264617
resolver
ensp
ENSMUSP00000264618
resolver
ensp
ENSMUSP00000264620
resolver
ensp
ENSMUSP00000264626
resolver
ensp
ENSMUSP00000264627
resolver
ensp
ENSMUSP00000264633
resolver
enst
ENSMUST00000112446
resolver
enst
ENSMUST00000131855
resolver
genesymbol
Eif2d
resolver
genesymbol_syn
Lgtn
resolver
uniprot
A0A0R4J298
resolver
uniprot
E9PUG7
resolver
uniprot
Q3TDE0
resolver
uniprot
Q3THV5
resolver
uniprot
Q3TTP4
resolver
uniprot
Q8C491
resolver
uniprot
Q8CBF1
resolver
uniprot
Q8CC17
resolver
uniprot
Q8R1I9
resolver
uniprot
Q8R3M5
resolver
uniprot_entry
A0A0R4J298_MOUSE
resolver
uniprot_entry
E9PUG7_MOUSE
resolver
uniprot_entry
EIF2D_MOUSE
resolver
uniprot_sec
Q3TDE0
resolver
uniprot_sec
Q3THV5
resolver
uniprot_sec
Q3TTP4
resolver
uniprot_sec
Q8C491
resolver
uniprot_sec
Q8CBF1
resolver
uniprot_sec
Q8CC17
resolver
uniprot_sec
Q8R1I9
resolver
uniprot_sec
Q8R3M5
resolver
amino_acid_sequence
MFAKAFRVKSNTAIKGSDRRKLRADVTAAFPALGTDQISELIPGKEELNVVKLYVHKGDSVTVYTSGGNPILFELEKNLYPTVYTLWAYPDILPTFITWPLVLEKLVGGADLMLPGVVVPPTGLPQVQQGDLCAIALVGNRAPVAIGVAAMSTAQMLASGLKGKGVSVLHTYQDHLWRSGDKSSPPAIAPLDPTDSCEEKVHLGLQGNLKSLTLDGEEENGQVPLREASEDTSSRAPSQDSLDGKPLQEQMDDLLLRCFLHALKSRVKKADLPLLTSTLLGSHMFSCCPEGQQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSKGVESIVAVDWRHPRITSFVIPEPSLTSQTVQEVSREQPYLPPDIKSLYCVPANMTQLFLESGHKKGSTLEGSEVRKIITDYAKRNRLVDADNRNLVKLDPILCDCILEKNEQHLVTKLPWDCLLTRCLKNMQPAYQVTFPGQEPILKKGKLCPIDITLALKTYNKKVTVVRNLETYGLDPCSVAAILQQRCQASTIVSPAPGAKDSLQVQVQGNQIHHLGQLLLEEYRLPGKYIQGLEKAPKPGKK
uniprot
proteins
function
FUNCTION: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
62830
uniprot
proteins
protein_family
EIF2D family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9070942
uniprot
proteins
sequence_length
570
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins