Gp6
entrez
243816
canonical
uniprot
P0C191
canonical
ensembl
ENSMUSG00000078810
resolver
ensp
ENSMUSP00000104231
resolver
ensp
ENSMUSP00000145740
resolver
ensp
ENSMUSP00000361668
resolver
enst
ENSMUST00000206928
resolver
genesymbol
Gp6
resolver
uniprot
E9QPN2
resolver
uniprot_entry
GPVI_MOUSE
resolver
uniprot_sec
E9QPN2
resolver
amino_acid_sequence
MSPASPTFFCIGLCVLQVIQTQSGPLPKPSLQAQPSSLVPLGQSVILRCQGPPDVDLYRLEKLKPEKYEDQDFLFIPTMERSNAGRYRCSYQNGSHWSLPSDQLELIATGVYAKPSLSAHPSSAVPQGRDVTLKCQSPYSFDEFVLYKEGDTGSYKRPEKWYRANFPIITVTAAHSGTYRCYSFSSSSPYLWSAPSDPLVLVVTGLSATPSQVPTEESFPVTESSRRPSILPTNKISTTEKPMNITASPEGLSPPFGFAHQHYAKGNLVRICLGATIIIILLGLLAEDWHSRKKCLQHRMRALQRPLPPLPLA
uniprot
proteins
function
FUNCTION: Collagen receptor involved in collagen-induced platelet adhesion and activation (PubMed:16139873, PubMed:24368846). Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. {ECO:0000269|PubMed:10961879, ECO:0000269|PubMed:16139873, ECO:0000269|PubMed:16254207, ECO:0000269|PubMed:24368846}.
uniprot
proteins
mass_dalton
34595
uniprot
proteins
pubmed
10961879
uniprot
proteins
pubmed
16139873
uniprot
proteins
pubmed
16254207
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
24368846
uniprot
proteins
sequence_length
313
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:24368846}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins