Taar2
entrez
209512
canonical
uniprot
Q5QD17
canonical
ensembl
ENSMUSG00000059763
resolver
ensp
ENSMUSP00000078137
resolver
enst
ENSMUST00000079134
resolver
genesymbol
Taar2
resolver
genesymbol_syn
Gm225
resolver
genesymbol_syn
Gpr58
resolver
uniprot
A6H6B2
resolver
uniprot
Q80T53
resolver
uniprot_entry
TAAR2_MOUSE
resolver
uniprot_sec
A6H6B2
resolver
uniprot_sec
Q80T53
resolver
amino_acid_sequence
MASFEAQQETFDCSEYGNGSCPENERSLGVRAAMYSLMACAIFITIFGNLAMIISISYFKQLHTPTNLLILSMAVTDFLLGFTIMPYSMVRSVENCWYFGLTFCKIHYSFDLMLSITSIFHLCSVAVDRFYAICHPLHYCTKMTIPVVRRLLLVCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFVAGFFTPSSMMVGIYGKIFAVSKKHARVIDNLPENQNNQMRKDKKAAKTLGIVMGVFLLCWFPCFFTILLDPFLNFSTPAVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSHFHNTNLFTQKETE
uniprot
proteins
function
FUNCTION: Orphan olfactory receptor specific for trace amines (By similarity). Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors (By similarity). Ligand-binding causes a conformation change that triggers signaling via the G(s)-class of G proteins which activate adenylate cyclase (By similarity). May also be required to provide olfactory input into limbic brain areas to regulate emotional behaviors likely via modulation of the dopamine system (PubMed:35431833). {ECO:0000250|UniProtKB:Q5QD04, ECO:0000269|PubMed:35431833}.
uniprot
proteins
mass_dalton
38517
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12679517
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15718104
uniprot
proteins
pubmed
16878137
uniprot
proteins
pubmed
23624375
uniprot
proteins
pubmed
35431833
uniprot
proteins
sequence_length
339
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5QD04}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 37..57; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 107..127; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 151..171; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 196..216; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 252..272; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 288..310; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins