Slc39a3
entrez
106947
canonical
uniprot
Q99K24
canonical
ensembl
ENSMUSG00000046822
resolver
ensp
ENSMUSP00000057094
resolver
ensp
ENSMUSP00000113147
resolver
ensp
ENSMUSP00000128256
resolver
enst
ENSMUST00000059551
resolver
enst
ENSMUST00000117276
resolver
enst
ENSMUST00000168076
resolver
genesymbol
Slc39a3
resolver
genesymbol_syn
Zip3
resolver
uniprot
A0A452J893
resolver
uniprot_entry
A0A452J893_MOUSE
resolver
uniprot_entry
S39A3_MOUSE
resolver
amino_acid_sequence
MTKLLVAKVLCMVGVFFFMLLGSLLPVKVIEADLEKAHRSKKVLSLCNTFGGGVFLATCFNALLPAVRDKLQQVLSLGHISTDYPLAETLMMVGFFLTVFVEQLVLTFRRERPPFIDLETFNAGSDAGSDSEYESPFVGVGNRSHSLYPEPTAHTHGAGLRLRELGRPGPLRLLSLVFALSAHSVFEGLALGLQEEGERVVSLFVGVAIHETLVAVALGISMARSAVPLRDAAKLAVTVSAMIPVGIGLGLGIESARSVASSVASALLQGLAGGTFLFVTFLEILAKELEERSEQLLKVLFLVLGYAVLAGMVFLKW
uniprot
proteins
function
FUNCTION: Transporter for the divalent cation Zn(2+). Mediates the influx of Zn(2+) into cells from extracellular space (PubMed:14525987, PubMed:15634741, PubMed:35169020). Controls Zn(2+) accumulation into dentate gyrus granule cells in the hippocampus (PubMed:35169020). Mediates Zn(2+) reuptake from the secreted milk within the alveolar lumen (PubMed:19458277). {ECO:0000269|PubMed:14525987, ECO:0000269|PubMed:15634741, ECO:0000269|PubMed:19458277, ECO:0000269|PubMed:35169020}.
uniprot
proteins
mass_dalton
34002
uniprot
proteins
protein_family
ZIP transporter (TC 2.A.5) family
uniprot
proteins
pubmed
14525987
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15634741
uniprot
proteins
pubmed
15964816
uniprot
proteins
pubmed
19458277
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
35169020
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15634741}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:19458277}; Multi-pass membrane protein {ECO:0000255}. Note=Localized primarily at the cell surface but also found in a perinuclear compartment in HC11 cells (PubMed:15634741). In mammary epithelial cell, localized primary to the apical membrane (PubMed:19458277). {ECO:0000269|PubMed:15634741, ECO:0000269|PubMed:19458277}.
uniprot
proteins
transmembrane_region
TRANSMEM 4..24; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 173..193; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 200..220; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 233..253; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 295..315; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins