Riok2
entrez
67045
canonical
uniprot
Q9CQS5
canonical
ensembl
ENSMUSG00000116564
resolver
ensp
ENSMUSP00000024620
resolver
enst
ENSMUST00000024620
resolver
genesymbol
Riok2
resolver
uniprot
Q91XF3
resolver
uniprot_entry
RIOK2_MOUSE
resolver
uniprot_sec
Q91XF3
resolver
amino_acid_sequence
MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPCSLIASIASLKHGGCNKILRELVKHKLIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEAGQQLALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVIMELINGYPLCQIHHVEDPASVYDEAMELIVKLGNHGLIHGDFNEFNLMLDKDDHITMIDFPQMVSTSHPNAEWYFDRDVKCIREFFMKRFSYESELYPTFSDIRKEDSLDVEVSASGYTKEMQADDELLHPVGPDDKITETEEDSDFTFSDEEMLEKAKVWRSELEKEADPADESGGSWCCSSTDSKQIKDGGLPEESAHVSSFEVTALSQAVEEMERQVLPHRSVTEFSEESRRTENDGQPGQRSPAGSEDCDDEPPHLIALSSVNREFRPFRDEESMSSVTRHRTRTLSVTSAGSALSCSTIPPELVKQKVKRQLTRQQKAAARRRLQKGEANVFTKQRRENMQNIKSSLEAASFWGD
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. May regulate the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, may regulate this function. {ECO:0000250|UniProtKB:Q9BVS4}.
uniprot
proteins
mass_dalton
62490
uniprot
proteins
post_translational_modification
PTM: Autophosphorylated (in vitro). Phosphorylation affects the timing of the metaphase-anaphase transition. {ECO:0000250|UniProtKB:Q9BVS4}.
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
RIO-type Ser/Thr kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
547
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BVS4}.
uniprot
proteins