PITPNC1
entrez
26207
canonical
uniprot
Q9UKF7
canonical
ensembl
ENSG00000154217
resolver
ensp
ENSP00000463626
resolver
ensp
ENSP00000464006
resolver
enst
ENST00000580974
resolver
genesymbol
PITPNC1
resolver
hgnc
HGNC:21045
resolver
uniprot
A0A0C4DGP0
resolver
uniprot
A8K473
resolver
uniprot
J3QR20
resolver
uniprot
Q96I07
resolver
uniprot_entry
A0A0C4DGP0_HUMAN
resolver
uniprot_entry
PITC1_HUMAN
resolver
uniprot_sec
A8K473
resolver
uniprot_sec
J3QR20
resolver
uniprot_sec
Q96I07
resolver
amino_acid_sequence
MLLKEYRICMPLTVDEYKIGQLYMISKHSHEQSDRGEGVEVVQNEPFEDPHHGNGQFTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDTIFDNEAKDVEREVCFIDIACDEIPERYYKESEDPKHFKSEKTGRGQLREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISISSIPLLPSSVRSAPSSAPSTPLSTDAPEFLSVPKDRPRKKSAPETLTLPDPEKKATLNLPGMHSSDKPCRPKSE
uniprot
proteins
function
FUNCTION: [Isoform 1]: Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes (PubMed:10531358, PubMed:22822086). Binds PA derived from the phospholipase D signaling pathway and among the cellular PA species, preferably binds to the C16:0/16:1 and C16:1/18:1 PA species (PubMed:22822086). {ECO:0000269|PubMed:10531358, ECO:0000269|PubMed:22822086}.; FUNCTION: [Isoform 2]: Catalyzes the transfer of phosphatidylinositol between membranes. {ECO:0000269|PubMed:22822086}.
uniprot
proteins
mass_dalton
38388
uniprot
proteins
protein_family
PI transfer class IIB subfamily
uniprot
proteins
protein_family
PtdIns transfer protein family
uniprot
proteins
pubmed
10531358
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
22822086
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:10531358}. Note=Primarily localized in the cytosol, interfaces with membranes to bind and transfer lipids. {ECO:0000305|PubMed:22822086}.
uniprot
proteins