LYZL6
entrez
57151
canonical
uniprot
O75951
canonical
ensembl
ENSG00000275722
resolver
ensembl
ENSG00000277042
resolver
ensp
ENSP00000482955
resolver
ensp
ENSP00000483358
resolver
ensp
ENSP00000483897
resolver
ensp
ENSP00000488304
resolver
enst
ENST00000612374
resolver
enst
ENST00000615905
resolver
enst
ENST00000618542
resolver
enst
ENST00000632590
resolver
genesymbol
HEL-S-6a
resolver
genesymbol
LYZL6
resolver
genesymbol_syn
LYC1
resolver
genesymbol_syn
LYZL6
resolver
hgnc
HGNC:29614
resolver
uniprot
A0A080YUZ6
resolver
uniprot
Q6UW30
resolver
uniprot_entry
A0A080YUZ6_HUMAN
resolver
uniprot_entry
LYZL6_HUMAN
resolver
uniprot_sec
Q6UW30
resolver
amino_acid_sequence
MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNISKINENADGSFDYGLFQINSHYWCNDYKSYSENLCHVDCQDLLNPNLLAGIHCAKRIVSGARGMNNWVEWRLHCSGRPLFYWLTGCRLR
uniprot
proteins
ec_number
3.2.1.17
uniprot
proteins
function
FUNCTION: May be involved sperm-egg plasma membrane adhesion and fusion during fertilization (PubMed:28182716). Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus (PubMed:24013621, PubMed:28182716). Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH (PubMed:28182716). Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6 (PubMed:28182716). {ECO:0000269|PubMed:24013621, ECO:0000269|PubMed:28182716}.
uniprot
proteins
mass_dalton
16956
uniprot
proteins
protein_family
Glycosyl hydrolase 22 family
uniprot
proteins
pubmed
10213461
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16014814
uniprot
proteins
pubmed
24013621
uniprot
proteins
pubmed
28182716
uniprot
proteins
sequence_length
148
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:28182716}. Cell surface {ECO:0000269|PubMed:28182716}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9DA11}. Note=Detected on the postacrosomal membrane of mature spermatozoa (PubMed:28182716). {ECO:0000269|PubMed:28182716}.
uniprot
proteins