CFAP57
entrez
149465
canonical
uniprot
Q96MR6
canonical
ensembl
ENSG00000243710
resolver
ensp
ENSP00000361570
resolver
ensp
ENSP00000435310
resolver
ensp
ENSP00000479773
resolver
ensp
ENSP00000561739
resolver
ensp
ENSP00000561740
resolver
ensp
ENSP00000624548
resolver
ensp
ENSP00000778429
resolver
enst
ENST00000610710
resolver
genesymbol
CFAP57
resolver
genesymbol_syn
WDR65
resolver
hgnc
HGNC:26485
resolver
uniprot
A0A087WVY5
resolver
uniprot
A6NKQ3
resolver
uniprot
Q17RI9
resolver
uniprot
Q5TAI0
resolver
uniprot_entry
A0A087WVY5_HUMAN
resolver
uniprot_entry
CFA57_HUMAN
resolver
uniprot_sec
A6NKQ3
resolver
uniprot_sec
Q17RI9
resolver
uniprot_sec
Q5TAI0
resolver
amino_acid_sequence
MSAVVAQTLHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETVQEKPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSPPESNLVYWLWEKQKVMAIVRIDTQNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFAEGTLKQTSFQRGEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPTNGSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAGPGRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQLYSITMSLTEISKGEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNLLIDDIRSFKEYSVRGCGECSFSNGGHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLSTGKRETECVLKSCSYNCVTVSPDAKIIFAVGSDHTLKEIADSLILREISAFDVTYTAIVISHSGRMMFVGTSVGTIRAMKYPLPLQKEFNEYQAHAGPITKMLLTFDDQFLLTAAEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQVMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQVLRTEKEKQDVYHHEHIEDLLDKQSRELQDMECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTTLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYEKKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIETLKGEQMKLQGVIKSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELGKFKFVLDYKIKELKKQIEPRENEIRVMKEQIQEMEAELENFHKQNTQLELNITELWQKLRATDQEMRRERQKERDLEALVKRFKTDLHNCVAYIQEPRLLKEKVRGLFEKYVQRADMVEIAGLNTDLQQEYTRQREHLERNLATLKKKVVKEGELHRTDYVRIMQENVSLIKEINELRRELKFTRSQVYDLEAALKLTKKVRPQEVSETEPSRDMLSTAPTARLNEQEETGRIIEMQRLEIQRLRDQIQEQEQVTGFHTLAGVRLPSLSNSEVDLEVKTN
uniprot
proteins
disease_involvement
DISEASE: Spermatogenic failure 95 (SPGF95) [MIM:620917]: An autosomal recessive, male infertility disorder characterized by markedly reduced progressive sperm motility and multiple morphologic abnormalities of the flagella, including irregularly shaped, short, absent, coiled, and bent flagella. {ECO:0000269|PubMed:36752199}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Associates with components of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility, and might act as an inner dynein arm (IDA) hub or linkage. {ECO:0000305|PubMed:32764743}.
uniprot
proteins
mass_dalton
144961
uniprot
proteins
protein_family
CFAP57 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21574244
uniprot
proteins
pubmed
32764743
uniprot
proteins
pubmed
36752199
uniprot
proteins
sequence_length
1250
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:32764743}.
uniprot
proteins