Htr7
entrez
15566
canonical
uniprot
P32304
canonical
ensembl
ENSMUSG00000024798
resolver
ensp
ENSMUSP00000097105
resolver
ensp
ENSMUSP00000126150
resolver
ensp
ENSMUSP00000126847
resolver
enst
ENSMUST00000099505
resolver
enst
ENSMUST00000164639
resolver
enst
ENSMUST00000166074
resolver
genesymbol
Htr7
resolver
uniprot
B6VJS2
resolver
uniprot
B6VJS3
resolver
uniprot
F6ZW06
resolver
uniprot
F7CNY5
resolver
uniprot
Q14A50
resolver
uniprot_entry
5HT7R_MOUSE
resolver
uniprot_entry
B6VJS2_MOUSE
resolver
uniprot_entry
B6VJS3_MOUSE
resolver
uniprot_entry
F6ZW06_MOUSE
resolver
uniprot_entry
F7CNY5_MOUSE
resolver
uniprot_sec
Q14A50
resolver
amino_acid_sequence
MMDVNSSGRPDLYGHLRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFPEVTASPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQPESVISLNGVVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNCDHCGKKGHDT
uniprot
proteins
function
FUNCTION: G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:8394987). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (By similarity). HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity (By similarity). {ECO:0000250|UniProtKB:P34969, ECO:0000269|PubMed:8394987}.
uniprot
proteins
mass_dalton
49916
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8394987
uniprot
proteins
sequence_length
448
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P34969}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P34969}.
uniprot
proteins
transmembrane_region
TRANSMEM 87..111; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:P34969"; TRANSMEM 122..143; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:P34969"; TRANSMEM 156..181; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:P34969"; TRANSMEM 202..222; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:P34969"; TRANSMEM 241..263; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:P34969"; TRANSMEM 330..355; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:P34969"; TRANSMEM 367..390; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:P34969
uniprot
proteins