Taar9
entrez
319107
canonical
uniprot
Q923Y6
canonical
ensembl
ENSRNOG00000026096
resolver
ensp
ENSRNOP00000037691
resolver
genesymbol
Taar9
resolver
genesymbol_syn
Ta3
resolver
genesymbol_syn
Tar3
resolver
genesymbol_syn
Trar3
resolver
uniprot_entry
TAAR9_RAT
resolver
amino_acid_sequence
MELCYENVNGSCIKSSYSPWPRAILYAVLGLGALLAVFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHTCFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFTISVSGVCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKQQARKIEGSANQPQASSESYKERVARRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSRTNLFSEEAGAG
uniprot
proteins
function
FUNCTION: Olfactory receptor specific for trace amines, such as triethylamine, N-methylpiperidine, N,N-dimethylcyclohexylamine (DMCHA), beta-phenylethylamine (beta-PEA), cadaverine (CAD) and polyamines such as spermidine (PubMed:22545963, PubMed:34600890). Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors (By similarity). Trace amine-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS) (By similarity). In mature olfactory sensory neurons, Taar9 is coupled with GNAL/G(olf)G alpha protein and mediates activation of adenylate cyclase activity to activate cAMP signaling and eventually transmit odorant signals to achieve membrane depolarization (By similarity). In immature olfactory sensory neurons, Taar9 is coupled with GNAS/G(s) G alpha proteins (By similarity). {ECO:0000250|UniProtKB:Q5QD04, ECO:0000269|PubMed:22545963, ECO:0000269|PubMed:34600890}.
uniprot
proteins
mass_dalton
37846
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11459929
uniprot
proteins
pubmed
22545963
uniprot
proteins
pubmed
33799339
uniprot
proteins
pubmed
34600890
uniprot
proteins
pubmed
36551251
uniprot
proteins
sequence_length
338
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5QD04}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5QD04}.
uniprot
proteins
transmembrane_region
TRANSMEM 24..48; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 59..80; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 96..118; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 139..160; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 187..208; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 247..270; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 284..304; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q5QD04
uniprot
proteins