Snrpb
entrez
20638
canonical
uniprot
P27048
canonical
ensembl
ENSMUSG00000027404
resolver
ensp
ENSMUSP00000099488
resolver
enst
ENSMUST00000103199
resolver
genesymbol
Snrpb
resolver
uniprot
Q3UJT1
resolver
uniprot_entry
RSMB_MOUSE
resolver
uniprot_sec
Q3UJT1
resolver
amino_acid_sequence
MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGLPPGRGTPMGMPPPGMRPPPPGMRGLL
uniprot
proteins
function
FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:28263986). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:19470752). {ECO:0000250|UniProtKB:P14678, ECO:0000269|PubMed:19470752, ECO:0000269|PubMed:28263986}.
uniprot
proteins
mass_dalton
23656
uniprot
proteins
post_translational_modification
PTM: Methylated by PRMT5 (PubMed:28263986). Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine (By similarity). {ECO:0000250|UniProtKB:P14678, ECO:0000305|PubMed:28263986}.
uniprot
proteins
protein_family
SnRNP SmB/SmN family
uniprot
proteins
pubmed
1376292
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19470752
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
28263986
uniprot
proteins
sequence_length
231
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P14678}. Nucleus {ECO:0000269|PubMed:19470752}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000250|UniProtKB:P14678}.
uniprot
proteins