SERTAD3
entrez
29946
canonical
uniprot
Q9UJW9
canonical
ensembl
ENSG00000167565
resolver
ensp
ENSP00000325414
resolver
ensp
ENSP00000375882
resolver
ensp
ENSP00000469245
resolver
ensp
ENSP00000535408
resolver
ensp
ENSP00000535409
resolver
ensp
ENSP00000535410
resolver
ensp
ENSP00000535411
resolver
ensp
ENSP00000535412
resolver
ensp
ENSP00000535413
resolver
ensp
ENSP00000535414
resolver
ensp
ENSP00000535415
resolver
ensp
ENSP00000535416
resolver
ensp
ENSP00000591175
resolver
ensp
ENSP00000591176
resolver
ensp
ENSP00000591177
resolver
ensp
ENSP00000591178
resolver
ensp
ENSP00000591179
resolver
ensp
ENSP00000591180
resolver
ensp
ENSP00000591181
resolver
ensp
ENSP00000591182
resolver
ensp
ENSP00000591183
resolver
ensp
ENSP00000591184
resolver
ensp
ENSP00000591185
resolver
ensp
ENSP00000591186
resolver
ensp
ENSP00000617027
resolver
ensp
ENSP00000617028
resolver
enst
ENST00000322354
resolver
enst
ENST00000392028
resolver
enst
ENST00000865349
resolver
enst
ENST00000865350
resolver
enst
ENST00000865351
resolver
enst
ENST00000865352
resolver
enst
ENST00000865353
resolver
enst
ENST00000865354
resolver
enst
ENST00000865355
resolver
enst
ENST00000865356
resolver
enst
ENST00000865357
resolver
enst
ENST00000921116
resolver
enst
ENST00000921117
resolver
enst
ENST00000921118
resolver
enst
ENST00000921119
resolver
enst
ENST00000921120
resolver
enst
ENST00000921121
resolver
enst
ENST00000921122
resolver
enst
ENST00000921123
resolver
enst
ENST00000921124
resolver
enst
ENST00000921125
resolver
enst
ENST00000921126
resolver
enst
ENST00000921127
resolver
enst
ENST00000946968
resolver
enst
ENST00000946969
resolver
genesymbol
SERTAD3
resolver
genesymbol_syn
RBT1
resolver
hgnc
HGNC:17931
resolver
uniprot
B3KQB3
resolver
uniprot
Q96CQ2
resolver
uniprot_entry
SRTD3_HUMAN
resolver
uniprot_sec
B3KQB3
resolver
uniprot_sec
Q96CQ2
resolver
amino_acid_sequence
MVGGLKRKHSDLEEEEERWEWSPAGLQSYQQALLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQAALRLAPAPALPPEPLFLGEEDFSLSATIGSILRELDTSMDGTEPPQNPVTPLGLQNEVPPQPDPVFLEALSSRYLGDSGLDDFFLDIDTSAVEKEPARAPPEPPHNLFCAPGSWEWNELDHIMEIILGS
uniprot
proteins
function
FUNCTION: Antiviral interferon-stimulated protein that plays a role in innate immunity and in the suppression of viruses through different mechanisms (PubMed:33147462, PubMed:36594413). Plays a role in the late phase response of TLR-induced immune effector expression (By similarity). During influenza infection, interacts with PB2, PB1, and PA to disrupt the formation of the viral RdRp complex (PubMed:33147462). Inhibits zika virus by interacting with the capsid protein in the nucleolus and reducing its abundance through proteasomal degradation (PubMed:36594413). Strong transcriptional coactivator (PubMed:10982866). {ECO:0000250|UniProtKB:Q9ERC3, ECO:0000269|PubMed:10982866, ECO:0000269|PubMed:33147462, ECO:0000269|PubMed:36594413}.
uniprot
proteins
mass_dalton
21769
uniprot
proteins
pubmed
10982866
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
33147462
uniprot
proteins
pubmed
36594413
uniprot
proteins
sequence_length
196
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10982866}.
uniprot
proteins