Lzts1
entrez
266711
canonical
uniprot
Q8CFC9
canonical
ensembl
ENSRNOG00000011826
resolver
ensembl
ENSRNOG00055004022
resolver
ensembl
ENSRNOG00060016849
resolver
ensembl
ENSRNOG00065005040
resolver
ensp
ENSRNOP00000015800
resolver
ensp
ENSRNOP00055004903
resolver
ensp
ENSRNOP00060023184
resolver
ensp
ENSRNOP00065005135
resolver
enst
ENSRNOT00000015799
resolver
enst
ENSRNOT00055006410
resolver
enst
ENSRNOT00060028811
resolver
enst
ENSRNOT00065007385
resolver
genesymbol
Lzts1
resolver
uniprot_entry
LZTS1_RAT
resolver
amino_acid_sequence
MGSVSSLISGHSLHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGRGKSSSKMGKSEDFFYIKVSQKARGSHRPDYTALSSGDMGGQTGVDFDPATPPKLMPFSSQLEMSSDKAAVRPTAFKPVLPRSGAILHSSPESTNHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQLDPLVTPVGPTSRFGGSAHNITQGIILQDSNMMSLKALSFSDGGSKLAHPGKVEKGSSCVRSPLSTDECTIQELEQKLLQRETALQKLQRSFDEKEFASGQTFEERPRRTRDELECLEPKSKLKPASQKSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTNFAPALEETQWEVCQKSGEISLLKQQLKESQMEVNAKASEILSLKAQLKDTRGKLEGMELKTQDLESALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELLELRAQAALHRDAAPLGPPGIGLTFSEDIPALQRELDRLRAELKEERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYLAMYQRNQRLEKALQQLARGDIAGEPFEIDLEGADIPYEDIIATEI
uniprot
proteins
function
FUNCTION: Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as tumor suppressor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
67565
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on serine residues. Hyperphosphorylated by the cAMP-dependent kinase PKA during cell-cycle progression (By similarity). {ECO:0000250}.; PTM: Ubiquitinated by the ECS(ASB7) complex, leading to its degradation. {ECO:0000250|UniProtKB:Q9Y250}.
uniprot
proteins
protein_family
LZTS family
uniprot
proteins
pubmed
12415013
uniprot
proteins
sequence_length
601
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12415013}. Cell membrane {ECO:0000250}. Cell projection, dendritic spine {ECO:0000269|PubMed:12415013}. Postsynaptic density {ECO:0000269|PubMed:12415013}. Synapse {ECO:0000269|PubMed:12415013}. Note=Associated with the plasma membrane and with microtubules (By similarity). Detected in dendritic spines, especially in the postsynaptic density. {ECO:0000250}.
uniprot
proteins