Sdcbp2
entrez
228765
canonical
uniprot
Q99JZ0
canonical
ensembl
ENSMUSG00000027456
resolver
ensp
ENSMUSP00000028950
resolver
ensp
ENSMUSP00000350640
resolver
enst
ENSMUST00000028950
resolver
genesymbol
Sdcbp2
resolver
uniprot
Q3UN51
resolver
uniprot_entry
SDCB2_MOUSE
resolver
uniprot_sec
Q3UN51
resolver
amino_acid_sequence
MSVLYPSLEDLKVGQVIQAQGRASPTMPTLPAPMASAPPLSELYPNLAELESYMGLSLSSQEVQKNLTQIPDSDNMVVTSPGPGQVVAPVSGNNLGILRAEIKPGVREIHLCKDERGKTGLRLQAVDKGLFVQLVQANTPASLVGLRFGDQILQIDGCDCAGWNTHKAHKVLKKASAEKIVMVIRDRPFQRTVTMHKDSSGQVGFSIKKGKIVSVVKGSSAARNGLLTNHYVCEVNGQNVIGLKDKKVTEILTTAGDVITLTIIPTVIYEHMIKRLSPLLLHHTMDHSIPDT
uniprot
proteins
function
FUNCTION: Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival. {ECO:0000250|UniProtKB:Q9H190}.
uniprot
proteins
mass_dalton
31565
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
292
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H190}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9H190}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9H190}. Cell membrane {ECO:0000250|UniProtKB:Q9H190}. Nucleus speckle {ECO:0000250|UniProtKB:Q9H190}. Note=Associates with intracellular membranes and enriched in the apical region of the cell and in intracellular compartments. Colocalizes with TM4SF1 in the apical region of the cell. Predominantly targeted to nuclear PIP2 pools. Shuttles between several subcellular compartments. PIP2 plays an important role in the distribution of SDCBP2. {ECO:0000250|UniProtKB:Q9H190}.
uniprot
proteins