Ctps2
entrez
55936
canonical
uniprot
P70303
canonical
ensembl
ENSMUSG00000031360
resolver
ensp
ENSMUSP00000033727
resolver
ensp
ENSMUSP00000107920
resolver
ensp
ENSMUSP00000107921
resolver
ensp
ENSMUSP00000107922
resolver
ensp
ENSMUSP00000288343
resolver
ensp
ENSMUSP00000288348
resolver
ensp
ENSMUSP00000288350
resolver
genesymbol
Ctps2
resolver
uniprot
Q3TPQ2
resolver
uniprot
Q3TT59
resolver
uniprot_entry
PYRG2_MOUSE
resolver
uniprot_sec
Q3TPQ2
resolver
uniprot_sec
Q3TT59
resolver
activity_regulation
ACTIVITY REGULATION: Strongly inhibited by CTP. {ECO:0000250|UniProtKB:Q9NRF8}.
uniprot
proteins
amino_acid_sequence
MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAIQEWVMNQAKVSVDGNKEDPQICVIELGGTIGDIEGMAFVEAFRQFQFKAKKENFYNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSIYRVPLLLEEQGVVKYFQERLGLPINDCSSNLLFKWKAMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEPVTKAEDPVKFHEAWQKLCLADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGICLGMQLAVIEFARNCLNLKDANSTEFEPNTPVPLVIDMPEHNPGDLGGTMRLGLRRTVFTTENSILKKLYGDVPYIEERHRHRYEVNPNLINQFENKDLCFVGEDVDGKRMEIVELTSHPYFIGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAHLQQMNKLPYSDGYSDASDDSFPEAKLAELDLN
uniprot
proteins
ec_number
6.3.4.2
uniprot
proteins
function
FUNCTION: CTP synthase involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. {ECO:0000250|UniProtKB:Q9NRF8}.
uniprot
proteins
mass_dalton
65514
uniprot
proteins
pathway_participation
PATHWAY: Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2. {ECO:0000250|UniProtKB:Q9NRF8}.
uniprot
proteins
protein_family
CTP synthase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
34583994
uniprot
proteins
pubmed
38438357
uniprot
proteins
sequence_length
586
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9NRF8}. Nucleus {ECO:0000250|UniProtKB:Q9NRF8}. Note=Cytoplasmic and nuclear; detected in long filamentous structures named cytoophidium. {ECO:0000250|UniProtKB:Q9NRF8}.
uniprot
proteins