Lipa
entrez
16889
canonical
uniprot
Q9Z0M5
canonical
ensembl
ENSMUSG00000024781
resolver
ensp
ENSMUSP00000053270
resolver
ensp
ENSMUSP00000136967
resolver
enst
ENSMUST00000049572
resolver
enst
ENSMUST00000178114
resolver
genesymbol
Lipa
resolver
genesymbol_syn
Lip1
resolver
uniprot
Q3TEL5
resolver
uniprot
Q8C2G7
resolver
uniprot_entry
LICH_MOUSE
resolver
uniprot_entry
Q3TEL5_MOUSE
resolver
uniprot_sec
Q8C2G7
resolver
amino_acid_sequence
MQLQGLVFVFTIGILLSRVPTGTVSAVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ
uniprot
proteins
ec_number
3.1.1.13
uniprot
proteins
function
FUNCTION: Catalyzes the deacylation of cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. Hydrolyzes triglycerides (1,2,3-triacylglycerol) and diglycerides (such as 1,2-diacylglycerol and 1,3-diacylglycerol) with preference for the acyl moieties at the sn-1 or sn-3 positions. {ECO:0000250|UniProtKB:P38571}.
uniprot
proteins
mass_dalton
45325
uniprot
proteins
post_translational_modification
PTM: Glycosylation is not essential for catalytic activity. {ECO:0000250|UniProtKB:P38571}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
Lipase family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8725147
uniprot
proteins
sequence_length
397
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000250|UniProtKB:Q64194}.
uniprot
proteins