Tnfrsf8
entrez
25069
canonical
uniprot
P97525
canonical
ensembl
ENSRNOG00000016782
resolver
ensp
ENSRNOP00000022967
resolver
enst
ENSRNOT00000022968
resolver
genesymbol
Tnfrsf8
resolver
genesymbol_syn
Cd30
resolver
uniprot
A0A0G2K7Z6
resolver
uniprot
F1LNN5
resolver
uniprot_entry
F1LNN5_RAT
resolver
uniprot_entry
TNR8_RAT
resolver
uniprot_sec
A0A0G2K7Z6
resolver
amino_acid_sequence
MSILLKAAGLLFLGMLQAFPKDRPLDTTCTGDLSYYPGEAARNCCYQCPSGLSPTQPCPQGPATARSSVILTTTNEDRKCTACVTCLPGLVEKAPCSGNSPRICECQPGMYCSTPAVNSCARCSEKTVVKFPDTAEKNTICDLPSPGSGPNGSNPDDCKTLTSHTTPQAIPTLESPANDSVRSLLPKQVTDFVNEGATKLVKVPESSSSKASMPSPDPGNAEMNMTLKLPPPGTVPDISTSENSMEPASTASTLSLLVDARTSSRMQPTSPLSTGTPFLDPGSMLFWVAMVVLLVGSASFLLCYWKACRRRFQRKFHLNYLQQTFQPKMEQVDSCPTEKLTQLQRSGSVTDSSAGHTLSPLSPPAVETGASVGTACLETLPLLDDSITGNSFAPREPPEPRVSTEHTNNRIEKIYIMKADTVIVGSVKTEVPEGRAPVGSTESELEAELEVDHTPHYPEQETEPPLGSCTEVMFSVEEGGKEDHEPTTVSEK
uniprot
proteins
function
FUNCTION: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts (By similarity). Regulates gene expression through activation of NF-kappa-B (PubMed:8982082). {ECO:0000250|UniProtKB:P28908, ECO:0000269|PubMed:8982082}.
uniprot
proteins
mass_dalton
52613
uniprot
proteins
protein_family
TNFR8 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
8982082
uniprot
proteins
sequence_length
492
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P28908}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 283..303; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins