NT5C3B
entrez
115024
canonical
uniprot
Q969T7
canonical
ensembl
ENSG00000141698
resolver
ensp
ENSP00000389948
resolver
ensp
ENSP00000569697
resolver
genesymbol
NT5C3B
resolver
genesymbol_syn
NT5C3L
resolver
hgnc
HGNC:28300
resolver
uniprot
A8MWB9
resolver
uniprot
C9JKC4
resolver
uniprot
Q7L3B7
resolver
uniprot_entry
5NT3B_HUMAN
resolver
uniprot_sec
A8MWB9
resolver
uniprot_sec
C9JKC4
resolver
uniprot_sec
Q7L3B7
resolver
amino_acid_sequence
MAEEVSTLMKATVLMRQPGRVQEIVGALRKGGGDRLQVISDFDMTLSRFAYNGKRCPSSYNILDNSKIISEECRKELTALLHHYYPIEIDPHRTVKEKLPHMVEWWTKAHNLLCQQKIQKFQIAQVVRESNAMLREGYKTFFNTLYHNNIPLFIFSAGIGDILEEIIRQMKVFHPNIHIVSNYMDFNEDGFLQGFKGQLIHTYNKNSSACENSGYFQQLEGKTNVILLGDSIGDLTMADGVPGVQNILKIGFLNDKVEERRERYMDSYDIVLEKDETLDVVNGLLQHILCQGVQLEMQGP
uniprot
proteins
ec_number
3.1.3.5
uniprot
proteins
ec_number
3.1.3.91
uniprot
proteins
function
FUNCTION: Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233). {ECO:0000269|PubMed:23223233, ECO:0000269|PubMed:24603684}.
uniprot
proteins
mass_dalton
34389
uniprot
proteins
protein_family
Pyrimidine 5'-nucleotidase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23223233
uniprot
proteins
pubmed
24603684
uniprot
proteins
sequence_length
300
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins