CREM
entrez
1390
canonical
uniprot
Q03060
canonical
ensembl
ENSG00000095794
resolver
ensp
ENSP00000265372
resolver
ensp
ENSP00000341875
resolver
ensp
ENSP00000344365
resolver
ensp
ENSP00000346804
resolver
ensp
ENSP00000349387
resolver
ensp
ENSP00000354593
resolver
ensp
ENSP00000363853
resolver
ensp
ENSP00000363858
resolver
ensp
ENSP00000363866
resolver
ensp
ENSP00000379225
resolver
ensp
ENSP00000393538
resolver
ensp
ENSP00000417165
resolver
ensp
ENSP00000417327
resolver
ensp
ENSP00000417460
resolver
ensp
ENSP00000417562
resolver
ensp
ENSP00000417807
resolver
ensp
ENSP00000418336
resolver
ensp
ENSP00000418798
resolver
ensp
ENSP00000419018
resolver
ensp
ENSP00000419075
resolver
ensp
ENSP00000419684
resolver
ensp
ENSP00000419810
resolver
ensp
ENSP00000420437
resolver
ensp
ENSP00000420511
resolver
ensp
ENSP00000420681
resolver
ensp
ENSP00000509489
resolver
ensp
ENSP00000510546
resolver
ensp
ENSP00000660496
resolver
enst
ENST00000344351
resolver
enst
ENST00000374721
resolver
enst
ENST00000460270
resolver
enst
ENST00000474362
resolver
genesymbol
CREM
resolver
hgnc
HGNC:2352
resolver
uniprot
A8K014
resolver
uniprot
A8K3J7
resolver
uniprot
A8K6A1
resolver
uniprot
A8MPQ2
resolver
uniprot
B4DXC1
resolver
uniprot
C9J785
resolver
uniprot
C9JZ10
resolver
uniprot
E9PAR2
resolver
uniprot
E9PAR4
resolver
uniprot
E9PB41
resolver
uniprot
E9PHM1
resolver
uniprot
G5E998
resolver
uniprot
O75519
resolver
uniprot
Q14501
resolver
uniprot
Q14503
resolver
uniprot
Q14504
resolver
uniprot
Q14505
resolver
uniprot
Q14506
resolver
uniprot
Q15731
resolver
uniprot
Q16114
resolver
uniprot
Q16116
resolver
uniprot
Q5T9H7
resolver
uniprot
Q5W1A6
resolver
uniprot
Q5W1A7
resolver
uniprot
Q5W1A8
resolver
uniprot
Q5W1A9
resolver
uniprot
Q5W1B0
resolver
uniprot
Q5W1B2
resolver
uniprot
Q7Z2Q6
resolver
uniprot
Q8IVD4
resolver
uniprot
Q96AG7
resolver
uniprot
Q9NZ98
resolver
uniprot
Q9NZ99
resolver
uniprot
Q9NZB9
resolver
uniprot_entry
CREM_HUMAN
resolver
uniprot_entry
E9PAR2_HUMAN
resolver
uniprot_entry
E9PB41_HUMAN
resolver
uniprot_entry
G5E998_HUMAN
resolver
uniprot_sec
A8K014
resolver
uniprot_sec
A8K3J7
resolver
uniprot_sec
A8K6A1
resolver
uniprot_sec
A8MPQ2
resolver
uniprot_sec
B4DXC1
resolver
uniprot_sec
C9J785
resolver
uniprot_sec
C9JZ10
resolver
uniprot_sec
E9PAR4
resolver
uniprot_sec
E9PHM1
resolver
uniprot_sec
O75519
resolver
uniprot_sec
Q14501
resolver
uniprot_sec
Q14503
resolver
uniprot_sec
Q14504
resolver
uniprot_sec
Q14505
resolver
uniprot_sec
Q14506
resolver
uniprot_sec
Q15731
resolver
uniprot_sec
Q16114
resolver
uniprot_sec
Q16116
resolver
uniprot_sec
Q5T9H7
resolver
uniprot_sec
Q5W1A6
resolver
uniprot_sec
Q5W1A7
resolver
uniprot_sec
Q5W1A8
resolver
uniprot_sec
Q5W1A9
resolver
uniprot_sec
Q5W1B0
resolver
uniprot_sec
Q5W1B2
resolver
uniprot_sec
Q7Z2Q6
resolver
uniprot_sec
Q8IVD4
resolver
uniprot_sec
Q96AG7
resolver
uniprot_sec
Q9NZ98
resolver
uniprot_sec
Q9NZ99
resolver
uniprot_sec
Q9NZB9
resolver
amino_acid_sequence
MTMETVESQHDGSITASLTESKSAHVQTQTGQNSIPALAQVSVAGSGTRRGSPAVTLVQLPSGQTIHVQGVIQTPQPWVIQSSEIHTVQVAAIAETDESAESEGVIDSHKRREILSRRPSYRKILNELSSDVPGVPKIEEERSEEEGTPPSIATMAVPTSIYQTSTGQYIAIAQGGTIQISNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFVPGSQVVVQDEETELAPSHMAAATGDMPTYQIRAPTAALPQGVVMAASPGSLHSPQQLAEEATRKRELRLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTDY
uniprot
proteins
function
FUNCTION: Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550). {ECO:0000269|PubMed:10373550}.; FUNCTION: [Isoform 6]: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter. {ECO:0000250}.
uniprot
proteins
mass_dalton
37006
uniprot
proteins
post_translational_modification
PTM: Isoform 9 is ubiquitinated by CDC34 and RAD6B in order to be degraded by the proteasome. {ECO:0000269|PubMed:10373550}.; PTM: Stimulated by phosphorylation. Phosphorylated on Ser-116 by TSSK4 in vitro. {ECO:0000250|UniProtKB:P27699, ECO:0000250|UniProtKB:Q01147}.
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
pubmed
10373550
uniprot
proteins
pubmed
11044457
uniprot
proteins
pubmed
12397208
uniprot
proteins
pubmed
14511788
uniprot
proteins
pubmed
1461747
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16143638
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
7916662
uniprot
proteins
pubmed
8206879
uniprot
proteins
pubmed
8622971
uniprot
proteins
sequence_length
345
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.; SUBCELLULAR LOCATION: [Isoform 6]: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins