Tfip11
entrez
288718
canonical
uniprot
Q5U2Y6
canonical
ensembl
ENSRNOG00000000663
resolver
ensembl
ENSRNOG00055002143
resolver
ensembl
ENSRNOG00065005884
resolver
ensp
ENSRNOP00000000828
resolver
ensp
ENSRNOP00055002559
resolver
ensp
ENSRNOP00065006224
resolver
enst
ENSRNOT00000000828
resolver
enst
ENSRNOT00055003432
resolver
enst
ENSRNOT00065008805
resolver
genesymbol
Tfip11
resolver
genesymbol_syn
Stip
resolver
uniprot_entry
TFP11_RAT
resolver
amino_acid_sequence
MSLSHLYRDGEGHLDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDEERPSFGGKRARDYSAPVNFISAGLKKGAAEEADSEDSDAEEKPVKQEDFPKDLGPKKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQSLQDFPVADSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRVSKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHSVPDEGVPLLAQLPPTAGKEAKVPGFALPELEHNLQLLIERTEQEIIQSDRQLQYERDMVVSLSHELEKTAEVLAHEERVISNLSKVLALVEECEHRMQPHGADPLTLDECARIFETLQDKYYEEYRLADRADLAVAIVYPLVKDYFKDWHPLEDSNYGTQIISKWKSLLENDQLLSHSSQDLSSDAFHRLMWEVWMPFVRNVVAQWQPRNCEPMVDFLDSWAHIIPVWILDNILDQLIFPKLQKEVDNWNPLTDTVPIHSWIHPWLPLMQARLEPLYSPVRSKLSSALQKWHPSDASAKLILQPWKEVLTPGSWEAFMLRNIVPKLGMCLGELVINPHQQHMDAFYWVMDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK
uniprot
proteins
function
FUNCTION: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
96152
uniprot
proteins
protein_family
TFP11/STIP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17289020
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
837
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles. {ECO:0000250}.
uniprot
proteins