Slc19a2
entrez
116914
canonical
uniprot
Q9EQN9
canonical
ensembl
ENSMUSG00000040918
resolver
ensp
ENSMUSP00000037561
resolver
ensp
ENSMUSP00000123870
resolver
genesymbol
Slc19a2
resolver
uniprot
Q8BRH5
resolver
uniprot
Q8R4Y1
resolver
uniprot_entry
S19A2_MOUSE
resolver
uniprot_sec
Q8BRH5
resolver
uniprot_sec
Q8R4Y1
resolver
amino_acid_sequence
MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVYNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGIVTDTPAANHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFRVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNADIYNGGVEAVSTLLGASAVFAVGYIKLSWSTWGEMTLFLCSLLIAAAVYVMDTVQSIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARGLGLCITTQFLIYASYFAAISVVFLANGIVSIIKKCRKQEDPSSSPQASTS
uniprot
proteins
function
FUNCTION: High-affinity transporter for the intake of thiamine (PubMed:11481326, PubMed:11592824, PubMed:12031504, PubMed:12393806, PubMed:22194418, PubMed:24961373, PubMed:35724964). Essential for spermatogenesis (PubMed:14567973, PubMed:14738878). Mediates H(+)-dependent pyridoxine transport (PubMed:35512554, PubMed:35724964). {ECO:0000269|PubMed:11481326, ECO:0000269|PubMed:11592824, ECO:0000269|PubMed:12031504, ECO:0000269|PubMed:12393806, ECO:0000269|PubMed:14567973, ECO:0000269|PubMed:14738878, ECO:0000269|PubMed:22194418, ECO:0000269|PubMed:35512554, ECO:0000269|PubMed:35724964}.
uniprot
proteins
mass_dalton
55676
uniprot
proteins
protein_family
Reduced folate carrier (RFC) transporter (TC 2.A.48) family
uniprot
proteins
pubmed
11386850
uniprot
proteins
pubmed
11481326
uniprot
proteins
pubmed
11592824
uniprot
proteins
pubmed
12031504
uniprot
proteins
pubmed
12393806
uniprot
proteins
pubmed
14567973
uniprot
proteins
pubmed
14738878
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16642288
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22194418
uniprot
proteins
pubmed
24961373
uniprot
proteins
pubmed
35512554
uniprot
proteins
pubmed
35724964
uniprot
proteins
pubmed
39217145
uniprot
proteins
sequence_length
498
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11481326, ECO:0000269|PubMed:11592824}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 29..46; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 72..92; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 129..149; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 187..207; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 296..316; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 335..355; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 361..381; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 387..407; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 424..444; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 457..477; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins