Aldh4a1
entrez
212647
canonical
uniprot
Q8CHT0
canonical
ensembl
ENSMUSG00000028737
resolver
ensp
ENSMUSP00000043821
resolver
ensp
ENSMUSP00000231874
resolver
enst
ENSMUST00000039818
resolver
genesymbol
Aldh4a1
resolver
uniprot
B1AXW8
resolver
uniprot
Q7TND0
resolver
uniprot
Q8BXM3
resolver
uniprot
Q8R0N1
resolver
uniprot
Q8R1S2
resolver
uniprot_entry
AL4A1_MOUSE
resolver
uniprot_sec
B1AXW8
resolver
uniprot_sec
Q7TND0
resolver
uniprot_sec
Q8BXM3
resolver
uniprot_sec
Q8R0N1
resolver
uniprot_sec
Q8R1S2
resolver
amino_acid_sequence
MLPLPSLRRSLLSHAWRGAGLRWKHTSSLKVTNEPILAFSQGSPERDALQKALKDLKGQMEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAIVQEATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWRYSYMQ
uniprot
proteins
ec_number
1.2.1.88
uniprot
proteins
function
FUNCTION: Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
61841
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.
uniprot
proteins
post_translational_modification
PTM: Acetylation of Lys-98, Lys-113 and Lys-401 is observed in liver mitochondria from fasted mice but not from fed mice.
uniprot
proteins
protein_family
Aldehyde dehydrogenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22516612
uniprot
proteins
pubmed
22868767
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
562
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
uniprot
proteins