T
entrez
20997
canonical
uniprot
P20293
canonical
ensembl
ENSMUSG00000062327
resolver
ensp
ENSMUSP00000074236
resolver
enst
ENSMUST00000074667
resolver
genesymbol
T
resolver
genesymbol
Tbxt
resolver
genesymbol_syn
T
resolver
uniprot
Q78ZW9
resolver
uniprot_entry
Q78ZW9_MOUSE
resolver
uniprot_entry
TBXT_MOUSE
resolver
amino_acid_sequence
MSSPGTESAGKSLQYRVDHLLSAVESELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVTADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNDHKDVMEEPGDCQQPGYSQWGWLVPGAGTLCPPASSHPQFGGSLSLPSTHGCERYPALRNHRSSPYPSPYAHRNSSPTYADNSSACLSMLQSHDNWSSLGVPGHTSMLPVSHNASPPTGSSQYPSLWSVSNGTITPGSQTAGVSNGLGAQFFRGSPAHYTPLTHTVSAATSSSSGSPMYEGAATVTDISDSQYDTAQSLLIASWTPVSPPSM
uniprot
proteins
disease_involvement
DISEASE: Note=Embryo lacking the T gene fail to form the notochord, the entire posterior region and the allantois, and die at about 10 days of gestation.
uniprot
proteins
function
FUNCTION: Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation (PubMed:7588606). Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site (PubMed:7588606, PubMed:8344258). {ECO:0000269|PubMed:7588606, ECO:0000269|PubMed:8344258}.
uniprot
proteins
mass_dalton
47440
uniprot
proteins
pubmed
2154694
uniprot
proteins
pubmed
7588606
uniprot
proteins
pubmed
8344258
uniprot
proteins
sequence_length
436
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:7588606}.
uniprot
proteins