LSM4
entrez
25804
canonical
uniprot
Q9Y4Z0
canonical
ensembl
ENSG00000130520
resolver
ensp
ENSP00000469468
resolver
ensp
ENSP00000475950
resolver
enst
ENST00000252816
resolver
enst
ENST00000593829
resolver
genesymbol
LSM4
resolver
hgnc
HGNC:17259
resolver
uniprot
U3KQK1
resolver
uniprot_entry
LSM4_HUMAN
resolver
uniprot_entry
U3KQK1_HUMAN
resolver
amino_acid_sequence
MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECYIRGSTIKYLRIPDEIIDMVKEEVVAKGRGRGGLQQQKQQKGRGMGGAGRGVFGGRGRGGIPGTGRGQPEKKPGRQAGKQ
uniprot
proteins
function
FUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). {ECO:0000269|PubMed:10523320, ECO:0000269|PubMed:28781166}.
uniprot
proteins
mass_dalton
15350
uniprot
proteins
protein_family
SnRNP Sm proteins family
uniprot
proteins
pubmed
10369684
uniprot
proteins
pubmed
10523320
uniprot
proteins
pubmed
10931946
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26912367
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
28781166
uniprot
proteins
sequence_length
139
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10523320, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28781166}.
uniprot
proteins