Elp2
entrez
307545
canonical
uniprot
Q496Z0
canonical
ensembl
ENSRNOG00000015301
resolver
ensp
ENSRNOP00000020601
resolver
genesymbol
Elp2
resolver
genesymbol_syn
Statip1
resolver
uniprot
Q562B6
resolver
uniprot_entry
ELP2_RAT
resolver
uniprot_sec
Q562B6
resolver
amino_acid_sequence
MVSSVLEVSYVFCCPNRARGALSWNSGPGGLLAFGTSCSVVLYDPQKKVVITNLNGHTARVNCLHWIRTEDGSPSTELVSGASDNRVIHWELENNQVLKSVRLQGHEGPVYAVHGIYQSGPSDGEQHALIASAASDSTVRLWSKKGSEVKCLQILKFGDGFVLTVCLSTLPDTDAPVLACGDDGGRIHLFVQQDDWFQKMLSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIWRLYMKPTSLETEDGSIRLKENTFTIKDGGVSTTVAVILETVLAGHENWVNAIHWQPSFYKDGVLHQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYGCQFGENGSMIIAHAFHGAMHLWKQSTVNPRQWAPEIVISGHFDGVQDLIWDPEGEFIITTSTDQTTRLFAPWKKKNQSQVTWHEIARPQIHGYNLKCLAMIDRFQFVSGADEKVLRVFSAPRNFVENFSVISRQSLSHMLYDEDNDLPEGATVPALGLSNKAVFEGDMTYLTSEEEELLSPAFGYPQVIFQPAVLSEPPTEDHLLQNTLWPEVQKLYGHGYEIFCVTCNNSKTLLASACKAAQKEHAAIILWSTTSWKQVQSLAYHTLTVTQMAFSPDDKFLLAVSRDRTWSLWKRQDVTSAEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGECNSSYNPMEHPINPCSSILDVGSCVTAVSVCPVLNPAQRYIVAVGLESGKICIYSWSKTNQETKDWTSCVETTPSQSHTLGIRRLCWKSCSGSTEQSEEGTEWLDFASCGEDHTVKIYRVNRCAL
uniprot
proteins
function
FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. {ECO:0000250|UniProtKB:Q6IA86}.
uniprot
proteins
mass_dalton
91746
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. {ECO:0000250|UniProtKB:Q6IA86}.
uniprot
proteins
protein_family
WD repeat ELP2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
821
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6IA86}. Nucleus {ECO:0000250|UniProtKB:Q6IA86}.
uniprot
proteins