TYW1B
entrez
441250
canonical
uniprot
Q6NUM6
canonical
ensembl
ENSG00000277149
resolver
ensp
ENSP00000482502
resolver
ensp
ENSP00000572377
resolver
ensp
ENSP00000784292
resolver
genesymbol
TYW1B
resolver
genesymbol_syn
RSAFD2
resolver
hgnc
HGNC:33908
resolver
uniprot
A0A087WZB2
resolver
uniprot
A6NG09
resolver
uniprot
B4DFY2
resolver
uniprot
Q3KQX2
resolver
uniprot_entry
TYW1B_HUMAN
resolver
uniprot_sec
A0A087WZB2
resolver
uniprot_sec
A6NG09
resolver
uniprot_sec
B4DFY2
resolver
uniprot_sec
Q3KQX2
resolver
amino_acid_sequence
MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPSLACANKCVFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLMLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKNKSKAISGC
uniprot
proteins
ec_number
4.1.3.44
uniprot
proteins
function
FUNCTION: Involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame (By similarity). Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity). {ECO:0000250|UniProtKB:Q08960}.
uniprot
proteins
mass_dalton
76946
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
uniprot
proteins
protein_family
TYW1 family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
668
uniprot
proteins