CLDN7
entrez
1366
canonical
uniprot
O95471
canonical
ensembl
ENSG00000181885
resolver
ensembl
ENSG00000288292
resolver
ensp
ENSP00000353475
resolver
ensp
ENSP00000396638
resolver
ensp
ENSP00000445131
resolver
ensp
ENSP00000500433
resolver
enst
ENST00000538261
resolver
enst
ENST00000673003
resolver
genesymbol
CLDN7
resolver
genesymbol_syn
CEPTRL2
resolver
genesymbol_syn
CPETRL2
resolver
hgnc
HGNC:2049
resolver
uniprot
A0A384ME58
resolver
uniprot
B2R9X7
resolver
uniprot
D3DTP0
resolver
uniprot
F5H496
resolver
uniprot
Q6IPN3
resolver
uniprot
Q7Z4Y7
resolver
uniprot
Q9BVN0
resolver
uniprot_entry
A0A384ME58_HUMAN
resolver
uniprot_entry
CLD7_HUMAN
resolver
uniprot_entry
F5H496_HUMAN
resolver
uniprot_sec
B2R9X7
resolver
uniprot_sec
D3DTP0
resolver
uniprot_sec
Q6IPN3
resolver
uniprot_sec
Q7Z4Y7
resolver
uniprot_sec
Q9BVN0
resolver
amino_acid_sequence
MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCSCPGNESKAGYRVPRSYPKSNSSKEYV
uniprot
proteins
function
FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space. {ECO:0000250}.
uniprot
proteins
mass_dalton
22418
uniprot
proteins
mutagenesis
MUTAGEN 32; /note="M->I: Interacts with CD81, and exhibits HCV infection susceptibility in cell culture."; /evidence="ECO:0000269|PubMed:20375010"; MUTAGEN 48; /note="K->E: Interacts with CD81, and exhibits HCV infection susceptibility in cell culture."; /evidence="ECO:0000269|PubMed:20375010
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000269|PubMed:16054130}.
uniprot
proteins
protein_family
Claudin family
uniprot
proteins
pubmed
12673207
uniprot
proteins
pubmed
14502431
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16054130
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
20375010
uniprot
proteins
sequence_length
211
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12673207, ECO:0000269|PubMed:14502431, ECO:0000269|PubMed:20375010}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:16054130}. Cell junction, tight junction {ECO:0000269|PubMed:16054130}. Note=Co-localizes with EPCAM at the basolateral cell membrane and tight junction. {ECO:0000269|PubMed:16054130}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 118..138; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 161..181; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins