Commd2
entrez
52245
canonical
uniprot
Q8BXC6
canonical
ensembl
ENSMUSG00000036513
resolver
ensp
ENSMUSP00000124819
resolver
enst
ENSMUST00000160959
resolver
genesymbol
Commd2
resolver
uniprot
Q497T6
resolver
uniprot
Q8BJI3
resolver
uniprot_entry
COMD2_MOUSE
resolver
uniprot_entry
Q497T6_MOUSE
resolver
uniprot_sec
Q8BJI3
resolver
amino_acid_sequence
MLLDLSEEHKEHLAFLPQVDTAVVAEFGRIAVEFLRRGSNPKIYEGAARKLNVSSDTIQHGVEGLTYLLTESSKLMISELDFQDSVFVLGFSEELNKLLLQLYLDNRKEIRTILNELAPRLPSYHSLEWRLDVQLASRSLRQQIKPAVTIKLHLDQNGDHSTHFLQTDPATLLHLVQQLEQALEEMKTNHCRRVVRSIK
uniprot
proteins
function
FUNCTION: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity). May down-regulate activation of NF-kappa-B (By similarity). {ECO:0000250|UniProtKB:Q86X83}.
uniprot
proteins
mass_dalton
22848
uniprot
proteins
protein_family
COMM domain-containing protein 2 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
199
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86X83}.
uniprot
proteins