P70619
uniprot
P70619
canonical
amino_acid_sequence
VNVGCVPKKVMWNTAVHSEFIHDHVDYGFQNCKSKFNWHVIKEKRDAYVSRLNNIYQNNLTKSHIEVIHGYATFRDGPQPTAEVNGKKFTAPHILIATGGVPTVPHENQIPGASLGITSDGFFQLEDLPSRSVIVGAGYIAVEIAGILSALGSKTSLMIRHDKVLRSFDSLISSNCTEELENAGGVEVLTVKKFSQVKEVKKTSSGLELHVVTALPGRKPTVTTIPDVDCLLWAIGRDPNSKGLNLNKLGIQTDDKGHILVDEFQNTNVKGVYAVGDVCGKALLTPVAIAAGRKLAHRLFEGKEDSRLDYDNIPTVVFSHPPIGTVGLTEDEAVHKYGKDNVKIYSTAFTPMYHAVTTRKTKCVMKMVCANKEEKVVGIHMQGIGCDEMLQGFAVAVKMGATKADFDNRVAIHPTSSEELVTLR
uniprot
proteins
ec_number
1.8.1.7
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol. {ECO:0000250|UniProtKB:P00390}.
uniprot
proteins
mass_dalton
46301
uniprot
proteins
protein_family
Class-I pyridine nucleotide-disulfide oxidoreductase family
uniprot
proteins
sequence_length
424
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P00390}. Cytoplasm {ECO:0000250|UniProtKB:P00390}.
uniprot
proteins