Tmem81
entrez
74626
canonical
uniprot
Q9D5K1
canonical
ensembl
ENSMUSG00000048174
resolver
ensp
ENSMUSP00000062565
resolver
ensp
ENSMUSP00000139911
resolver
ensp
ENSMUSP00000205027
resolver
enst
ENSMUST00000058167
resolver
enst
ENSMUST00000188789
resolver
genesymbol
Tmem81
resolver
uniprot
Q4VBF9
resolver
uniprot_entry
TMM81_MOUSE
resolver
uniprot_sec
Q4VBF9
resolver
amino_acid_sequence
MKTGAIVFILRSLLSITYLPLVLMTLDIPEELQKAVGRVIVNATGCSVTCGLGYKEETECEVGPDGVRRNCTFQRLECVTNWICGMLHFTIVHGKTFELNCLSSDILEKGQEAFRFTWRLARGIISTNDELFRPFRANSPFIGFKPAYEYNAGTYRCDVQLLKNLKFVKRLYFGLRVLPPKLVNLNFQQSLTEDQKLIDKGWEVNLDNGSKPHLPVWQRKVTSALGIGIVAGVVGGVLVSVAVFKALGGTDGSGGRTRL
uniprot
proteins
function
FUNCTION: Essential fertilization factor required for male fertility. Part of a conserved trimeric sperm complex with the essential fertilization factors IZUMO1 and SPACA6 which bridges sperm and oocyte membranes during fertilization by binding to IZUMO1R/JUNO on the oocyte. {ECO:0000250|UniProtKB:Q6P7N7}.
uniprot
proteins
mass_dalton
28748
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
39423812
uniprot
proteins
sequence_length
259
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:B8JI67}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins