Cycs
entrez
25309
canonical
uniprot
P62898
canonical
ensembl
ENSRNOG00000010452
resolver
ensembl
ENSRNOG00000065095
resolver
ensembl
ENSRNOG00055010600
resolver
ensembl
ENSRNOG00055026915
resolver
ensembl
ENSRNOG00060010835
resolver
ensembl
ENSRNOG00060026085
resolver
ensembl
ENSRNOG00065014463
resolver
ensembl
ENSRNOG00065023326
resolver
ensp
ENSRNOP00000014058
resolver
ensp
ENSRNOP00000094836
resolver
ensp
ENSRNOP00055014440
resolver
ensp
ENSRNOP00055038109
resolver
ensp
ENSRNOP00060014295
resolver
ensp
ENSRNOP00060037474
resolver
ensp
ENSRNOP00065018582
resolver
ensp
ENSRNOP00065032410
resolver
enst
ENSRNOT00000014058
resolver
enst
ENSRNOT00000102631
resolver
enst
ENSRNOT00055017936
resolver
enst
ENSRNOT00055046461
resolver
enst
ENSRNOT00060018337
resolver
enst
ENSRNOT00060045164
resolver
enst
ENSRNOT00065023877
resolver
enst
ENSRNOT00065039843
resolver
genesymbol
Cycs
resolver
uniprot
P00009
resolver
uniprot
Q8C2S2
resolver
uniprot_entry
CYC_RAT
resolver
uniprot_sec
P00009
resolver
uniprot_sec
Q8C2S2
resolver
amino_acid_sequence
MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAAGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKGERADLIAYLKKATNE
uniprot
proteins
function
FUNCTION: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; FUNCTION: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11605
uniprot
proteins
post_translational_modification
PTM: Binds 1 heme c group covalently per subunit.; PTM: Phosphorylation at Tyr-49 and Tyr-98 both reduce by half the turnover in the reaction with cytochrome c oxidase, down-regulating mitochondrial respiration. {ECO:0000250}.
uniprot
proteins
protein_family
Cytochrome c family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
191069
uniprot
proteins
pubmed
2834389
uniprot
proteins
pubmed
30980393
uniprot
proteins
pubmed
6130852
uniprot
proteins
pubmed
6263917
uniprot
proteins
sequence_length
105
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
uniprot
proteins