NRD1
entrez
4898
canonical
uniprot
O43847
canonical
ensembl
ENSG00000078618
resolver
ensp
ENSP00000262679
resolver
ensp
ENSP00000346890
resolver
ensp
ENSP00000444416
resolver
enst
ENST00000539524
resolver
genesymbol
NRD1
resolver
genesymbol
NRDC
resolver
genesymbol_syn
NRD1
resolver
hgnc
HGNC:7995
resolver
uniprot
A6NI41
resolver
uniprot
G3V1R5
resolver
uniprot
O15241
resolver
uniprot
O15242
resolver
uniprot
Q5VUL0
resolver
uniprot
Q6UUU9
resolver
uniprot
Q96HB2
resolver
uniprot
Q9NU57
resolver
uniprot_entry
G3V1R5_HUMAN
resolver
uniprot_entry
NRDC_HUMAN
resolver
uniprot_entry
Q6UUU9_HUMAN
resolver
uniprot_sec
A6NI41
resolver
uniprot_sec
O15241
resolver
uniprot_sec
O15242
resolver
uniprot_sec
Q5VUL0
resolver
uniprot_sec
Q96HB2
resolver
uniprot_sec
Q9NU57
resolver
amino_acid_sequence
MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTTLNLLPYHKIVK
uniprot
proteins
ec_number
3.4.24.61
uniprot
proteins
function
FUNCTION: Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs. Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination. Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH) (By similarity). {ECO:0000250|UniProtKB:Q8BHG1}.
uniprot
proteins
mass_dalton
131701
uniprot
proteins
protein_family
Peptidase M16 family
uniprot
proteins
pubmed
11042131
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28017472
uniprot
proteins
pubmed
9479496
uniprot
proteins
pubmed
9581555
uniprot
proteins
sequence_length
1151
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:28017472}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8BHG1}.
uniprot
proteins