Mchr1
entrez
207911
canonical
uniprot
Q8JZL2
canonical
ensembl
ENSMUSG00000050164
resolver
ensp
ENSMUSP00000126191
resolver
genesymbol
Mchr1
resolver
genesymbol_syn
Gpr24
resolver
genesymbol_syn
Slc1
resolver
uniprot
Q3UY93
resolver
uniprot
Q8K3M8
resolver
uniprot_entry
MCHR1_MOUSE
resolver
uniprot_sec
Q3UY93
resolver
uniprot_sec
Q8K3M8
resolver
amino_acid_sequence
MDLQASLLSTGPNASNISDGQDNFTLAGPPPRTRSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT
uniprot
proteins
function
FUNCTION: G protein-coupled receptor for melanin-concentrating hormone (MCH) that signals primarily through G(i/o) to inhibit adenylyl cyclase, and can additionally couple to G(q/11) to stimulate phospholipase C and mobilize intracellular calcium (By similarity). Predominantly localized within the central nervous system where it regulates various physiological processes including feeding behavior, energy homeostasis, stress/anxiety-related behaviors and sleep (PubMed:12072376, PubMed:15988472, PubMed:18380672). {ECO:0000250|UniProtKB:Q99705, ECO:0000269|PubMed:12072376, ECO:0000269|PubMed:15988472, ECO:0000269|PubMed:18380672}.
uniprot
proteins
mass_dalton
39120
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11159839
uniprot
proteins
pubmed
11471062
uniprot
proteins
pubmed
12072376
uniprot
proteins
pubmed
15093132
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15988472
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18380672
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
353
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q99705}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 46..66; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 80..100; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 117..139; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 162..182; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 205..225; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 257..277; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 295..315; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins