Alkbh7
entrez
66400
canonical
uniprot
Q9D6Z0
canonical
ensembl
ENSMUSG00000002661
resolver
ensp
ENSMUSP00000002737
resolver
ensp
ENSMUSP00000073775
resolver
genesymbol
Alkbh7
resolver
genesymbol_syn
Spata11
resolver
uniprot
Q8K1H3
resolver
uniprot
Q9CY41
resolver
uniprot
Q9D942
resolver
uniprot_entry
ALKB7_MOUSE
resolver
uniprot_sec
Q8K1H3
resolver
uniprot_sec
Q9CY41
resolver
uniprot_sec
Q9D942
resolver
amino_acid_sequence
MAGSRRLAMRLLSGCAWVRGSDSAVLGRLRDEAVVHPGFLSQEEEDTLTRELEPQLRRRRYEYDHWDAAIHGFRETEKSCWSDASQVILQRVRAAAFGPDQSLLSPVHVLDLEPRGYIKPHVDSVKFCGSTIAGLSLLSPSVMKLVHTQEPEQWLELLLEPGSLYILRGSARYDFSHEILRDEESFFGEHRVPRGRRISVICRSLPEGMGPGRPEEPPPAC
uniprot
proteins
ec_number
1.14.11.-
uniprot
proteins
function
FUNCTION: RNA demethylase that demethylates N(2)-dimethylguanosine and N(1)-methyladenosine within mitochondrial pre-tRNA regions. This demethylation activity plays a crucial role in regulating the processing of nascent polycistronic mitochondrial RNA, thereby influencing mitochondrial gene expression and overall mitochondrial activity (By similarity). In response to extensive DNA damage is required for programmed necrosis induced by alkylation and oxidation. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (By similarity). Involved in fatty acid metabolism (PubMed:23572141). {ECO:0000250|UniProtKB:Q9BT30, ECO:0000269|PubMed:23572141}.
uniprot
proteins
mass_dalton
24970
uniprot
proteins
protein_family
AlkB family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23572141
uniprot
proteins
sequence_length
221
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:23572141}.
uniprot
proteins