PROZ
entrez
8858
canonical
uniprot
P22891
canonical
ensembl
ENSG00000126231
resolver
ensp
ENSP00000344458
resolver
ensp
ENSP00000364697
resolver
ensp
ENSP00000675229
resolver
ensp
ENSP00000675233
resolver
genesymbol
PROZ
resolver
hgnc
HGNC:9460
resolver
uniprot
A6NMB4
resolver
uniprot
Q15213
resolver
uniprot
Q5JVF5
resolver
uniprot
Q5JVF6
resolver
uniprot_entry
PROZ_HUMAN
resolver
uniprot_sec
A6NMB4
resolver
uniprot_sec
Q15213
resolver
uniprot_sec
Q5JVF5
resolver
uniprot_sec
Q5JVF6
resolver
amino_acid_sequence
MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN
uniprot
proteins
function
FUNCTION: Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.
uniprot
proteins
mass_dalton
44744
uniprot
proteins
post_translational_modification
PTM: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19528533
uniprot
proteins
pubmed
20427285
uniprot
proteins
pubmed
2129367
uniprot
proteins
pubmed
2244898
uniprot
proteins
pubmed
2403355
uniprot
proteins
pubmed
2511201
uniprot
proteins
pubmed
9578570
uniprot
proteins
sequence_length
400
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins