Adam22
entrez
11496
canonical
uniprot
Q9R1V6
canonical
ensembl
ENSMUSG00000040537
resolver
ensp
ENSMUSP00000049120
resolver
ensp
ENSMUSP00000055000
resolver
ensp
ENSMUSP00000086139
resolver
ensp
ENSMUSP00000111043
resolver
ensp
ENSMUSP00000111044
resolver
ensp
ENSMUSP00000111046
resolver
ensp
ENSMUSP00000203499
resolver
ensp
ENSMUSP00000203500
resolver
ensp
ENSMUSP00000203501
resolver
ensp
ENSMUSP00000203502
resolver
ensp
ENSMUSP00000203503
resolver
ensp
ENSMUSP00000203506
resolver
enst
ENSMUST00000115385
resolver
enst
ENSMUST00000115386
resolver
genesymbol
Adam22
resolver
uniprot
D3YUP9
resolver
uniprot
D3YUQ0
resolver
uniprot
D6QSS8
resolver
uniprot
Q5TLI8
resolver
uniprot
Q5TLI9
resolver
uniprot
Q5TLJ0
resolver
uniprot
Q5TLJ1
resolver
uniprot
Q5TLJ2
resolver
uniprot
Q5TLJ3
resolver
uniprot
Q5TLJ4
resolver
uniprot
Q5TLJ5
resolver
uniprot
Q5TLJ6
resolver
uniprot
Q5TLJ7
resolver
uniprot
Q5TLJ8
resolver
uniprot
Q5TLJ9
resolver
uniprot
Q5TLK0
resolver
uniprot
Q5TLK1
resolver
uniprot
Q5TLK2
resolver
uniprot
Q5TLK3
resolver
uniprot
Q5TLK4
resolver
uniprot
Q5TLK5
resolver
uniprot
Q5TLK6
resolver
uniprot
Q5TLK7
resolver
uniprot
Q5TLK8
resolver
uniprot
Q8BSF2
resolver
uniprot
Q9R1V5
resolver
uniprot_entry
ADA22_MOUSE
resolver
uniprot_entry
D3YUP9_MOUSE
resolver
uniprot_entry
D3YUQ0_MOUSE
resolver
uniprot_entry
D6QSS8_MOUSE
resolver
uniprot_sec
Q5TLI8
resolver
uniprot_sec
Q5TLI9
resolver
uniprot_sec
Q5TLJ0
resolver
uniprot_sec
Q5TLJ1
resolver
uniprot_sec
Q5TLJ2
resolver
uniprot_sec
Q5TLJ3
resolver
uniprot_sec
Q5TLJ4
resolver
uniprot_sec
Q5TLJ5
resolver
uniprot_sec
Q5TLJ6
resolver
uniprot_sec
Q5TLJ7
resolver
uniprot_sec
Q5TLJ8
resolver
uniprot_sec
Q5TLJ9
resolver
uniprot_sec
Q5TLK0
resolver
uniprot_sec
Q5TLK1
resolver
uniprot_sec
Q5TLK2
resolver
uniprot_sec
Q5TLK3
resolver
uniprot_sec
Q5TLK4
resolver
uniprot_sec
Q5TLK5
resolver
uniprot_sec
Q5TLK6
resolver
uniprot_sec
Q5TLK7
resolver
uniprot_sec
Q5TLK8
resolver
uniprot_sec
Q8BSF2
resolver
uniprot_sec
Q9R1V5
resolver
amino_acid_sequence
MQAAAAASFWLLCVLGTCPLARCGRAGVASLKGLERGKENRFLERQSIIPLRLIYRLGGEDETQHNQLDTRVRGDPGGPQLTHVDKASFRVDAFGTSFVLDVLLNHELLSSGYVERQIEHGGKVVENKGGEHCYYQGQIRGNPVSFVALSTCHGLHGMFYDGNHTYLIEPEENEKSQESSHCHSVYKSRQFEFPLDDLPSEFQRVNITPPQFILKPRLKRRKRQLLRFPRNVEEETKYIELMIVNDHLMFKKHRLSVVYTNTYAKSVVNMADVIYKDQLKTRIVLVAMETWAADNKFAISENPLITLREFMKYRRDFIKEKADAVHLFSGSQFESSRSGAAYIGGICSLLRGGGVNEFGKTDLMAVTLAQSLAHNVGIISDKRKLASGECKCEDTWSGCIMGDTGYYLPKKFTQCNVEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECALEGAECCKKCTLTQDSQCSDGLCCKKCKFQPLGTVCREAVNDCDIREICSGNSSQCAPNVHKMDGYSCDGTQGICFGGRCKTRDRQCKYIWGQKVTASDRYCYEKLNIEGTEKGNCGKDKDTWTQCNKRDVLCGYLLCTNIGNIPRLGELDGEITSTLVVQQGRTLNCSGAHVKLEEDVDLGYVEDGTPCGPQMMCLEHRCLPVASFNFSTCSSSKAGTVCSGNGVCSNELKCVCNRHWTGADCGTHFPHNDDAKTGITLSGNGVAGTNIIIGIIAGTILVLALILGITAWGYKNYREQRQLPQGDYVKKPGDGDSFYSDFPPGGSTNSASSSKKRSNGLSHSWSERIPDTKHISDICENGRPRSNSWQGNMGGNKKKIRGKRFRPRSNSTETLSPAKSPSSSTGSIASSRKYPYPMPPLPDEGKTAGRQSARLWETSI
uniprot
proteins
function
FUNCTION: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1. {ECO:0000250|UniProtKB:Q9P0K1, ECO:0000269|PubMed:16990550}.
uniprot
proteins
mass_dalton
99715
uniprot
proteins
mutagenesis
MUTAGEN 509; /note="D->N: Fails to bind to LGI1."; /evidence="ECO:0000269|PubMed:16990550
uniprot
proteins
post_translational_modification
PTM: The precursor is cleaved by a furin endopeptidase. {ECO:0000250}.
uniprot
proteins
pubmed
10433968
uniprot
proteins
pubmed
15876356
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16990550
uniprot
proteins
pubmed
18974846
uniprot
proteins
pubmed
20089912
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26269648
uniprot
proteins
sequence_length
904
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20089912}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000269|PubMed:20089912}.
uniprot
proteins
transmembrane_region
TRANSMEM 735..755; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins