Ppp2r5c
entrez
26931
canonical
uniprot
Q60996
canonical
ensembl
ENSMUSG00000017843
resolver
ensp
ENSMUSP00000082053
resolver
ensp
ENSMUSP00000105458
resolver
ensp
ENSMUSP00000152282
resolver
ensp
ENSMUSP00000152865
resolver
ensp
ENSMUSP00000176105
resolver
ensp
ENSMUSP00000176106
resolver
ensp
ENSMUSP00000176107
resolver
ensp
ENSMUSP00000176112
resolver
ensp
ENSMUSP00000176113
resolver
ensp
ENSMUSP00000176116
resolver
ensp
ENSMUSP00000176121
resolver
genesymbol
Ppp2r5c
resolver
genesymbol_syn
mKIAA0044
resolver
uniprot
O35708
resolver
uniprot
Q6TQF7
resolver
uniprot
Q6ZQK4
resolver
uniprot
Q99KW8
resolver
uniprot
Q99N67
resolver
uniprot
Q99N68
resolver
uniprot_entry
2A5G_MOUSE
resolver
uniprot_entry
Q6ZQK4_MOUSE
resolver
uniprot_sec
O35708
resolver
uniprot_sec
Q6TQF7
resolver
uniprot_sec
Q99KW8
resolver
uniprot_sec
Q99N67
resolver
uniprot_sec
Q99N68
resolver
amino_acid_sequence
MLTCNKAGSGMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEAVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAVSIPVAMETDGPQFEDVQMLKKTVSDEARQAQKELKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR
uniprot
proteins
function
FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
60824
uniprot
proteins
protein_family
Phosphatase 2A regulatory subunit B56 family
uniprot
proteins
pubmed
12507892
uniprot
proteins
pubmed
15051958
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8617797
uniprot
proteins
pubmed
8752144
uniprot
proteins
sequence_length
524
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere {ECO:0000250}.
uniprot
proteins