Mgll
entrez
29254
canonical
uniprot
Q8R431
canonical
ensembl
ENSRNOG00000014508
resolver
ensp
ENSRNOP00000030271
resolver
ensp
ENSRNOP00000080270
resolver
enst
ENSRNOT00000110964
resolver
genesymbol
Mgll
resolver
genesymbol_syn
Mgl2
resolver
uniprot
A0A8I5ZPF3
resolver
uniprot
Q32PZ2
resolver
uniprot_entry
A0A8I5ZPF3_RAT
resolver
uniprot_entry
MGLL_RAT
resolver
uniprot_sec
Q32PZ2
resolver
amino_acid_sequence
MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLGHSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRIDSSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADRLCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGARCLP
uniprot
proteins
ec_number
3.1.1.23
uniprot
proteins
function
FUNCTION: Converts monoacylglycerides to free fatty acids and glycerol (PubMed:12136125). Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:12136125, PubMed:17649977). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (By similarity). {ECO:0000250|UniProtKB:O35678, ECO:0000269|PubMed:12136125, ECO:0000269|PubMed:17649977}.
uniprot
proteins
mass_dalton
33500
uniprot
proteins
pathway_participation
PATHWAY: Glycerolipid metabolism; triacylglycerol degradation. {ECO:0000250|UniProtKB:O35678}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
Monoacylglycerol lipase family
uniprot
proteins
pubmed
12136125
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17649977
uniprot
proteins
pubmed
9341166
uniprot
proteins
sequence_length
303
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35678}. Membrane {ECO:0000250|UniProtKB:O35678}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35678}.
uniprot
proteins