Trim58
entrez
216781
canonical
uniprot
Q5NCC9
canonical
ensembl
ENSMUSG00000037124
resolver
ensp
ENSMUSP00000074594
resolver
enst
ENSMUST00000075084
resolver
genesymbol
Trim58
resolver
genesymbol_syn
Gm16
resolver
uniprot_entry
TRI58_MOUSE
resolver
amino_acid_sequence
MATAPGERLQEEARCSVCLDFLQEPISVDCGHSFCLRCISEFCEKSDSAQGVYACPQCRGPFRPASFRPNRQLASLVDSVRQLGLGTGHAGSRQCARHGEDLSHFCEEDQTMLCWVCDTSPEHRSHRTETLQEAASRYQRMLRASLELVKKEMEEALTQEANVGKKTIIWKEKVEMQRQRFRLEFEKHRGFLAQEEQLQLRRLEEEERATLQRLRDSRNRLAQQNKALKELAEELEERSQRPAPGLLEGARGVLTRCEAITRLEPEAVPMDLKTVCRIPGMREMLRKFQVDVKLDPATAHPSLLLTADLRSVQDAEVWRDVPSNPERFDTWPCILGLQGFSSGRHYWEVIVGERAEWGLGVCRDSVLRKGETTPSPENGVWAMWLLRGNEYMVLSSPSVPVLQDERPRRIGIFLDYEAGEISFYNVTNGSYIYTFNHLFSGVLRPYFFVCDTTPLILPPMTEAAPGNWTPRGIFDLAAAARNEEY
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization. {ECO:0000250|UniProtKB:Q8NG06}.
uniprot
proteins
mass_dalton
55371
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:Q8NG06}.
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
25241935
uniprot
proteins
sequence_length
485
uniprot
proteins