Nyap1
entrez
243300
canonical
uniprot
Q6PFX7
canonical
ensembl
ENSMUSG00000045348
resolver
ensp
ENSMUSP00000113397
resolver
ensp
ENSMUSP00000148318
resolver
genesymbol
Nyap1
resolver
uniprot
E1CB66
resolver
uniprot
Q3UF51
resolver
uniprot
Q8BNR4
resolver
uniprot
Q8CCL6
resolver
uniprot_entry
NYAP1_MOUSE
resolver
uniprot_sec
E1CB66
resolver
uniprot_sec
Q3UF51
resolver
uniprot_sec
Q8BNR4
resolver
uniprot_sec
Q8CCL6
resolver
amino_acid_sequence
MNLLYRKTKLEWRQHKEEEAKRSSSKEAAPTGPVGPGAVPGPGVRVRDIASLRRSLRMGFMTMPASQEHTPHPCRSTMAPRSLSCHSVGSMDSVGGGPGGGLTEDSSTRRPPAKPRRHPSTKLSMAGPGAETPPSKKAGSQKPAPECRESSRKVPPQKPRRSPNTQLSVSFDESCAPAPSPRGANLPLQRLSRASRITGDLDAGAQEEEPVYIEMVGDVFRGGGRSGGGLAGPPLGSGGPTPPAAADSDSEDSEAIYEEMKYPLPEEAGDGRANGPPPLTAPSPPQQTHILQPHPHPHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRAPGDGVSRLPVLCHSKEPAGSTPAPQVPARERETPPLPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQTRGERELPNSHSMICPKAAGVPAAHPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGVGEPKTEEISVLHGMLCASSRPPVPGKSSPHSGAMGSAAGVLHHRSCLASPHSLPDPTGGSLTPLWTYPATAAGLKRPPAYDSLKAGGVLNKGCGMGAPSPMVKIQLQEQGTDGGAFASISCAHVIASAGTPEEEEEMGAAFGAGWALQRKVLYGGRKAKEVDTEEDGARAWNGSTEGPGKVEHEDRGPVPSGIPVRSQGAEGLLARIHHDRGGSRTALPVPCQTFPACHRNGDFTGGYRLGRSASTSGVRQAALHTPRPCSQPRDALSQTHPVLPLPLPPQPARERDGKLLEVIERKRCVCKEIKARHRPDRGLCKQESMPILPSWRRVPEPRKSGTPPCRRQHTVLWDTAI
uniprot
proteins
function
FUNCTION: Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis. {ECO:0000269|PubMed:21946561}.
uniprot
proteins
mass_dalton
87668
uniprot
proteins
mutagenesis
MUTAGEN 212; /note="Y->F: Abolishes binding to PIK3R2. Slight reduction of phosphorylation in HEK293T cells. Abolishes phosphorylation in HEK293T cells and in neurons; when associated with F-257."; /evidence="ECO:0000269|PubMed:21946561"; MUTAGEN 257; /note="Y->F: Reduced binding to PIK3R2. Slight reduction of phosphorylation in HEK293T cells. Abolishes phosphorylation in HEK293T cells and neurons; when associated with F-212."; /evidence="ECO:0000269|PubMed:21946561
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues by FYN upon stimulation with CNTN5. Phosphorylation begins at 14 dpc, reaches a peak during perinatal days in brain, then gradually decreases. {ECO:0000269|PubMed:21946561}.
uniprot
proteins
protein_family
NYAP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21946561
uniprot
proteins
sequence_length
833
uniprot
proteins