Rmi2
entrez
223970
canonical
uniprot
Q3UPE3
canonical
ensembl
ENSMUSG00000037991
resolver
ensp
ENSMUSP00000042676
resolver
genesymbol
Rmi2
resolver
genesymbol_syn
Gm929
resolver
uniprot
Q3V2Y5
resolver
uniprot_entry
RMI2_MOUSE
resolver
uniprot_sec
Q3V2Y5
resolver
amino_acid_sequence
MAAAASESLSSGGPGAVRLPRLPPLKVLAGQLRRHAEGGPGAWRLSRAAVGRAPLELVAVWMQGTVLAAEGGQARLRDSSGAFSVRGLERVPRGRPCLLPGKYVMVMGVVQACSPEPCLQAVKMTDLSDNPVHESMWELEVEDLHRNIP
uniprot
proteins
function
FUNCTION: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM. {ECO:0000250|UniProtKB:Q96E14}.
uniprot
proteins
mass_dalton
15838
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis. {ECO:0000250}.
uniprot
proteins
protein_family
RMI2 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
149
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Colocalizes with BLM at nuclear DNA repair foci. {ECO:0000250}.
uniprot
proteins