Dmc1
entrez
13404
canonical
uniprot
Q61880
canonical
ensembl
ENSMUSG00000022429
resolver
ensp
ENSMUSP00000023065
resolver
ensp
ENSMUSP00000155228
resolver
ensp
ENSMUSP00000328253
resolver
ensp
ENSMUSP00000328259
resolver
enst
ENSMUST00000023065
resolver
enst
ENSMUST00000229408
resolver
genesymbol
Dmc1
resolver
genesymbol_syn
Dmc1h
resolver
genesymbol_syn
Lim15
resolver
uniprot
A0A2R8W6Q0
resolver
uniprot
Q14AN8
resolver
uniprot
Q8C610
resolver
uniprot_entry
A0A2R8W6Q0_MOUSE
resolver
uniprot_entry
DMC1_MOUSE
resolver
uniprot_entry
Q14AN8_MOUSE
resolver
uniprot_entry
Q8C610_MOUSE
resolver
amino_acid_sequence
MKEDQVVQEESGFQDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGTGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Homologous DNA recombinase that catalyzes strand exchange during meiotic recombination (PubMed:17639081, PubMed:32610038, PubMed:37891173, PubMed:9660953, PubMed:9660954). Specifically required for meiotic recombination, facilitating the search and repair of DNA using the homolog rather than the sister chromatid, and can tolerate mismatches in heteroduplex DNA, unlike the higher-fidelity RAD51 (PubMed:17639081, PubMed:32610038). {ECO:0000269|PubMed:17639081, ECO:0000269|PubMed:32610038, ECO:0000269|PubMed:37891173, ECO:0000269|PubMed:9660953, ECO:0000269|PubMed:9660954}.
uniprot
proteins
mass_dalton
37821
uniprot
proteins
protein_family
DMC1 subfamily
uniprot
proteins
protein_family
RecA family
uniprot
proteins
pubmed
15834424
uniprot
proteins
pubmed
17639081
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21307306
uniprot
proteins
pubmed
22549958
uniprot
proteins
pubmed
30746471
uniprot
proteins
pubmed
30760716
uniprot
proteins
pubmed
30949703
uniprot
proteins
pubmed
32463460
uniprot
proteins
pubmed
32610038
uniprot
proteins
pubmed
37891173
uniprot
proteins
pubmed
8581742
uniprot
proteins
pubmed
8602360
uniprot
proteins
pubmed
9660953
uniprot
proteins
pubmed
9660954
uniprot
proteins
sequence_length
340
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Chromosome {ECO:0000269|PubMed:21307306, ECO:0000269|PubMed:22549958, ECO:0000269|PubMed:30746471, ECO:0000269|PubMed:30760716, ECO:0000269|PubMed:30949703, ECO:0000269|PubMed:32463460, ECO:0000269|PubMed:32610038}. Nucleus {ECO:0000269|PubMed:21307306}. Note=Binds single-stranded DNA (ssDNA) near the break site. {ECO:0000269|PubMed:32610038}.
uniprot
proteins