Klhl17
entrez
246757
canonical
uniprot
Q8K430
canonical
ensembl
ENSRNOG00000020302
resolver
ensembl
ENSRNOG00055015352
resolver
ensembl
ENSRNOG00060004853
resolver
ensembl
ENSRNOG00065010691
resolver
ensp
ENSRNOP00000027547
resolver
ensp
ENSRNOP00055021326
resolver
ensp
ENSRNOP00060006050
resolver
ensp
ENSRNOP00065013255
resolver
enst
ENSRNOT00055026221
resolver
enst
ENSRNOT00060008077
resolver
enst
ENSRNOT00065017311
resolver
genesymbol
Klhl17
resolver
uniprot_entry
KLH17_RAT
resolver
amino_acid_sequence
MQPRGERPAGRTQSPEHSSPGPGPEAPPPPQPPAPEAERARPRQARPAAPMEGAMQLLSREGHSVAHNSKRHYHDAFVAMSRMRQRGLLCDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESRQTHVTLHDIDPQALDQLVQFAYTAEIVVGEGNVQTLLPAASLLQLNGVRDACCKFLLSQLDPSNCLGIRGFADTHSCSDLLKAAHRYVLQHFVDVAKTEEFMLLPLKQVLELVSSDSLNVPSEEDVYRAVLSWVKHDVDTRRQHVPRLMKCVRLPLLSRDFLLGHVDAESLVRHHPDCKDLLIEALKFHLLPEQRGVLGTSRTRPRRCEGAGPVLFAVGGGSLFAIHGDCEAYDTRTDRWHVVASMSTRRARVGVAAVGNRLYAVGGYDGTSDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYAAGGYDGASCLNSAERYDPLTGTWTSIAAMSTRRRYVRVATLDGNLYAVGGYDSSSHLATVEKYEPQVNSWTPVASMLSRRSSAGVAVLEGALYVAGGNDGTSCLNSVERYSTKAGAWESVAPMNIRRSTHDLVAMDGWLYAVGGNDGSSSLNSIEKYNPRTNKWVAASCMFTRRSSVGVAVLELLNFPPPSSPTLSVSSTSL
uniprot
proteins
function
FUNCTION: Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes. The BCR(KLHL17) complex mediates the ubiquitination and subsequent degradation of GLUR6. May play a role in the actin-based neuronal function. {ECO:0000269|PubMed:17062563}.
uniprot
proteins
mass_dalton
69732
uniprot
proteins
mutagenesis
MUTAGEN 638..640; /note="Missing: No interaction with PDZK1."; /evidence="ECO:0000269|PubMed:16054660
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
12063253
uniprot
proteins
pubmed
16054660
uniprot
proteins
pubmed
17062563
uniprot
proteins
sequence_length
640
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic density {ECO:0000269|PubMed:12063253}. Synapse {ECO:0000269|PubMed:12063253}.
uniprot
proteins