Mturn
entrez
297109
canonical
uniprot
Q5XI20
canonical
ensembl
ENSRNOG00000010205
resolver
ensp
ENSRNOP00000096014
resolver
ensp
ENSRNOP00000105309
resolver
enst
ENSRNOT00000107913
resolver
genesymbol
Mturn
resolver
uniprot
A0A8I6ARQ2
resolver
uniprot_entry
A0A8I6ARQ2_RAT
resolver
uniprot_entry
MTURN_RAT
resolver
amino_acid_sequence
MDFQQLADVAEKWCSSTPFELIAAEETERRMDFYADPGVSFYVLCPDNGCGDSFHVWSESEDCLPFLQLAQDYISSCGKKTLQEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ
uniprot
proteins
function
FUNCTION: Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression (By similarity). Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser- 536' (By similarity). May be involved in early neuronal development (By similarity). {ECO:0000250|UniProtKB:Q7ZX36, ECO:0000250|UniProtKB:Q8N3F0}.
uniprot
proteins
mass_dalton
14832
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Tyr-34 is essential for its ability to promote megakaryocyte differentiation. {ECO:0000250|UniProtKB:Q8N3F0}.
uniprot
proteins
protein_family
MTURN family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
131
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8N3F0}.
uniprot
proteins