Ramp2
entrez
58966
canonical
uniprot
Q9JHJ1
canonical
ensembl
ENSRNOG00065003184
resolver
ensp
ENSRNOP00065003215
resolver
enst
ENSRNOT00065004495
resolver
genesymbol
Ramp2
resolver
uniprot_entry
RAMP2_RAT
resolver
amino_acid_sequence
MAPLRVERAPGGSQLAVTSAQRPAALRLPPLLLLLLLLLLGAVSTSPESLNQSHPTEDSLLSKGKMEDYETNVLPCWYYYKTSMDSVKDWCNWTLISRYYSNLRYCLEYEADKFGLGFPNPLAESIILEAHLIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLVTLVVWRSKDGDAQA
uniprot
proteins
function
FUNCTION: Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed:11556887). Required for the transport of CALCRL to the plasma membrane (By similarity). Together with CALCRL, form a receptor complex for adrenomedullin/ADM (PubMed:11556887). Together with CALCR, act as a receptor complex for calcitonin/CT/CALC. Together with CALCR, also act as a receptor complex for amylin/IAPP (By similarity). {ECO:0000250|UniProtKB:O60895, ECO:0000269|PubMed:11556887}.
uniprot
proteins
mass_dalton
20300
uniprot
proteins
protein_family
RAMP family
uniprot
proteins
pubmed
10733909
uniprot
proteins
pubmed
11230971
uniprot
proteins
pubmed
11556887
uniprot
proteins
sequence_length
182
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O60895}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:O60895}.
uniprot
proteins
transmembrane_region
TRANSMEM 151..172; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O60895
uniprot
proteins