Fuz
entrez
70300
canonical
uniprot
Q3UYI6
canonical
ensembl
ENSMUSG00000011658
resolver
ensp
ENSMUSP00000071194
resolver
ensp
ENSMUSP00000146434
resolver
ensp
ENSMUSP00000146681
resolver
ensp
ENSMUSP00000146725
resolver
ensp
ENSMUSP00000147169
resolver
ensp
ENSMUSP00000237244
resolver
enst
ENSMUST00000071207
resolver
enst
ENSMUST00000209039
resolver
genesymbol
Fuz
resolver
uniprot
A0A140LI55
resolver
uniprot
E9QL29
resolver
uniprot
Q9D0P9
resolver
uniprot_entry
A0A140LI55_MOUSE
resolver
uniprot_entry
E9QL29_MOUSE
resolver
uniprot_entry
FUZZY_MOUSE
resolver
uniprot_sec
Q9D0P9
resolver
amino_acid_sequence
MGDEGPGSPVHLLCLAASSGVPLFCRSSSGGAPSRQQLPFSVIGSLNGVHMFGQNLDVQLNSARTEDTTVVWKNFHDSITLIVLSSEEGTSELRLERMLHMVFGAMVLIVGLEELTNIRNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSAMQETLSGFAEATGTAFVSLLVSGRVVAATEGWWRLGMPEAVLLPWLVGSLPPQAARDYPVYLPHGSPTVPHRLLTLTLLRGLELCLLCGPRPPLGQLDPQLMERWWQPLLEPLRACLPLGPRALPEGFPLHSDILGLLLLHLELRRCLFTMEPSKDKEPSPEQRRRLLRNFYTLVATTHFPPEPGPAEKQEDTVYPAQMPRACYLVLGPGMGWQLVAVQLGLRLLLLLLSPHTPTHGLRSLATRTLQALTPLL
uniprot
proteins
function
FUNCTION: Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:19767740, PubMed:19877275, PubMed:27158779). May regulate the morphogenesis of hair follicles which depends on functional primary cilia (PubMed:20962855). Binds phosphatidylinositol 3-phosphate with highest affinity, followed by phosphatidylinositol 4-phosphate and phosphatidylinositol 5-phosphate (PubMed:35427153). {ECO:0000269|PubMed:19767740, ECO:0000269|PubMed:19877275, ECO:0000269|PubMed:20962855, ECO:0000269|PubMed:35427153, ECO:0000305|PubMed:27158779}.
uniprot
proteins
mass_dalton
45588
uniprot
proteins
protein_family
Fuzzy family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19767740
uniprot
proteins
pubmed
19877275
uniprot
proteins
pubmed
20962855
uniprot
proteins
pubmed
27158779
uniprot
proteins
pubmed
35427153
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q2HZX7}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q2HZX7}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000305}.
uniprot
proteins