Oas1b
entrez
23961
canonical
uniprot
Q60856
canonical
ensembl
ENSMUSG00000029605
resolver
genesymbol
Oas1b
resolver
genesymbol_syn
Flv
resolver
genesymbol_syn
Oias2
resolver
uniprot
A8YPE5
resolver
uniprot
A8YPE7
resolver
uniprot
A8YPE8
resolver
uniprot
A8YPE9
resolver
uniprot
E9QKP6
resolver
uniprot
Q78ZX0
resolver
uniprot
Q8JZN0
resolver
uniprot
Q8JZN4
resolver
uniprot
Q8VI98
resolver
uniprot_entry
OAS1B_MOUSE
resolver
uniprot_sec
A8YPE5
resolver
uniprot_sec
A8YPE7
resolver
uniprot_sec
A8YPE8
resolver
uniprot_sec
A8YPE9
resolver
uniprot_sec
E9QKP6
resolver
uniprot_sec
Q78ZX0
resolver
uniprot_sec
Q8JZN0
resolver
uniprot_sec
Q8JZN4
resolver
uniprot_sec
Q8VI98
resolver
amino_acid_sequence
MEQDLRSIPASKLDKFIENHLPDTSFCADLREVIDALCALLKDRSFRGPVRRMRASKGVKGKGTTLKGRSDADLVVFLNNLTSFEDQLNQQGVLIKEIKKQLCEVQHERRCGVKFEVHSLRSPNSRALSFKLSAPDLLKEVKFDVLPAYDLLDHLNILKKPNQQFYANLISGRTPPGKEGKLSICFMGLRKYFLNCRPTKLKRLIRLVTHWYQLCKEKLGDPLPPQYALELLTVYAWEYGSRVTKFNTAQGFRTVLELVTKYKQLQIYWTVYYDFRHQEVSEYLHQQLKKDRPVILDPADPTRNIAGLNPKDWRRLAGEAAAWLQYPCFKYRDGSSVCSWEVPTEVGVPMKYLLCRIFWLLFWSLFHFIFGKTSSG
uniprot
proteins
function
FUNCTION: Does not have 2'-5'-OAS activity, but can bind double-stranded RNA (PubMed:12396720, PubMed:27663720). The full-length protein displays antiviral activity against flaviviruses such as west Nile virus (WNV) via an alternative antiviral pathway independent of RNase L (PubMed:12080145, PubMed:16371364, PubMed:17904183, PubMed:27663720). The truncated form of the protein lacks antiviral activity (PubMed:12080145, PubMed:16371364, PubMed:17904183). {ECO:0000269|PubMed:12080145, ECO:0000269|PubMed:12396720, ECO:0000269|PubMed:16371364, ECO:0000269|PubMed:17904183, ECO:0000269|PubMed:27663720}.
uniprot
proteins
mass_dalton
43620
uniprot
proteins
protein_family
2-5A synthase family
uniprot
proteins
pubmed
12080145
uniprot
proteins
pubmed
12186974
uniprot
proteins
pubmed
12396720
uniprot
proteins
pubmed
16371364
uniprot
proteins
pubmed
17024523
uniprot
proteins
pubmed
1709495
uniprot
proteins
pubmed
17904183
uniprot
proteins
pubmed
18460447
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22305621
uniprot
proteins
pubmed
22623793
uniprot
proteins
pubmed
27663720
uniprot
proteins
sequence_length
376
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305|PubMed:22623793}; Single-pass type IV membrane protein {ECO:0000305|PubMed:22623793}.
uniprot
proteins
transmembrane_region
TRANSMEM 352..370; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins