Rgn
entrez
25106
canonical
uniprot
Q03336
canonical
ensembl
ENSRNOG00000007949
resolver
ensembl
ENSRNOG00055016646
resolver
ensembl
ENSRNOG00060022372
resolver
ensp
ENSRNOP00000010984
resolver
ensp
ENSRNOP00000103000
resolver
ensp
ENSRNOP00055022764
resolver
ensp
ENSRNOP00060032033
resolver
enst
ENSRNOT00000010984
resolver
enst
ENSRNOT00000123249
resolver
enst
ENSRNOT00055028283
resolver
enst
ENSRNOT00060038781
resolver
genesymbol
Rgn
resolver
genesymbol_syn
Smp30
resolver
uniprot
A0ABK0LNM0
resolver
uniprot
Q63496
resolver
uniprot
Q925W3
resolver
uniprot
Q9QWP2
resolver
uniprot_entry
A0ABK0LNM0_RAT
resolver
uniprot_entry
RGN_RAT
resolver
uniprot_sec
Q63496
resolver
uniprot_sec
Q925W3
resolver
uniprot_sec
Q9QWP2
resolver
amino_acid_sequence
MSSIKIECVLRENYRCGESPVWEEASKCLLFVDIPSKTVCRWDSISNRVQRVGVDAPVSSVALRQSGGYVATIGTKFCALNWEDQSVFILAMVDEDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYSLFPDHSVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYTVDAFDYDLPTGQISNRRTVYKMEKDEQIPDGMCIDVEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDYSEMYVTCARDGMSAEGLLRQPDAGNIFKITGLGVKGIAPYSYAG
uniprot
proteins
ec_number
3.1.1.17
uniprot
proteins
function
FUNCTION: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. {ECO:0000269|PubMed:15251439, ECO:0000269|PubMed:16585534, ECO:0000269|PubMed:8794449}.
uniprot
proteins
mass_dalton
33390
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; L-ascorbate biosynthesis via UDP-alpha-D-glucuronate pathway; L-ascorbate from UDP-alpha-D-glucuronate: step 3/4. {ECO:0000269|PubMed:16585534}.
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
SMP-30/CGR1 family
uniprot
proteins
pubmed
1420310
uniprot
proteins
pubmed
15251439
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16585534
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8348951
uniprot
proteins
pubmed
8569761
uniprot
proteins
pubmed
8794449
uniprot
proteins
pubmed
8979263
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins