RPL12
entrez
6136
canonical
uniprot
P30050
canonical
ensembl
ENSG00000197958
resolver
ensp
ENSP00000354739
resolver
genesymbol
RPL12
resolver
hgnc
HGNC:10302
resolver
uniprot
Q5VVV2
resolver
uniprot
Q6PB27
resolver
uniprot_entry
RL12_HUMAN
resolver
uniprot_sec
Q5VVV2
resolver
uniprot_sec
Q6PB27
resolver
amino_acid_sequence
MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS
uniprot
proteins
function
FUNCTION: Component of the large ribosomal subunit (PubMed:25901680). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:25901680). Binds directly to 26S ribosomal RNA (PubMed:25901680). {ECO:0000269|PubMed:25901680}.
uniprot
proteins
mass_dalton
17819
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated at Lys-48 and Lys-83 by RNF14 and RNF25 in response to ribosome collisions (ribosome stalling). {ECO:0000269|PubMed:36638793}.
uniprot
proteins
protein_family
Universal ribosomal protein uL11 family
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23636399
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24524803
uniprot
proteins
pubmed
25901680
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
36638793
uniprot
proteins
pubmed
8441690
uniprot
proteins
sequence_length
165
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:25901680}.
uniprot
proteins