Crls1
entrez
66586
canonical
uniprot
Q80ZM8
canonical
ensembl
ENSMUSG00000027357
resolver
ensp
ENSMUSP00000028835
resolver
ensp
ENSMUSP00000129137
resolver
ensp
ENSMUSP00000132682
resolver
enst
ENSMUST00000028835
resolver
enst
ENSMUST00000124836
resolver
genesymbol
Crls1
resolver
uniprot
A0A0C3SFZ5
resolver
uniprot
Q9D4U1
resolver
uniprot_entry
A0A0C3SFZ5_MOUSE
resolver
uniprot_entry
CRLS1_MOUSE
resolver
uniprot_sec
Q9D4U1
resolver
amino_acid_sequence
MLAWRVARGAWGPLRVALRPPGARLGRGGSRRALLPPAACCLGCLAERWRLRPAAFALRLPGAGPRTHCSGAGKAAPEPAAGGGGAAAQAPSARWVPASAASSYENPWTIPNLLSMTRIGLAPVLGYLILEEDFNVALGVFALAGLTDLLDGFIARNWANQKSALGSALDPLADKVLISILYISLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCCTAFTTAASAYSYYHYGRKTVQVIKGK
uniprot
proteins
ec_number
2.7.8.41
uniprot
proteins
function
FUNCTION: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. {ECO:0000250|UniProtKB:Q9UJA2}.
uniprot
proteins
mass_dalton
32502
uniprot
proteins
protein_family
CDP-alcohol phosphatidyltransferase class-I family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
35147173
uniprot
proteins
pubmed
36563328
uniprot
proteins
sequence_length
303
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9UJA2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9UJA2}.
uniprot
proteins
transmembrane_region
TRANSMEM 110..130; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 134..154; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 191..213; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 251..271; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 272..290; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins