Myo16
entrez
244281
canonical
uniprot
Q5DU14
canonical
ensembl
ENSMUSG00000039057
resolver
ensp
ENSMUSP00000146677
resolver
genesymbol
Myo16
resolver
genesymbol_syn
Kiaa0865
resolver
genesymbol_syn
Nyap3
resolver
uniprot
B2RX94
resolver
uniprot
E1CB68
resolver
uniprot
Q6GQW7
resolver
uniprot
Q8BUV4
resolver
uniprot_entry
MYO16_MOUSE
resolver
uniprot_sec
B2RX94
resolver
uniprot_sec
E1CB68
resolver
uniprot_sec
Q6GQW7
resolver
uniprot_sec
Q8BUV4
resolver
amino_acid_sequence
MEIDQCLLESLPLGQRQRLVKRMRCEQIKAYYEREKVFQKQEGPLKRSKPGKRQKVRFGLADMIQDAVIHHHDKEVLQLLKEGADPHTLVSSGGSLLHLCARYDNVFIAEVLIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLILAGANVFLQDVNGNIPLDYAVEGTESSAILLAYLDEKGVDLSSLRQIKLQRPLSMLTDVRHFLSSGGDVNEKNDDGVTLLHMACASGYKEVVLLLLEHGGDLNGTDDRYWTPLHLAAKYGQTTLVKLLLAHQANPHLVNCNGEKPSDIAASESIEEMLLKAEIAWEEKMKESPSAPSLAQEELYEILHDLPDLSSKLSPLVLPIAKQDSLLEKDIMFKDTTKGLCKQESQDGPPETSMTSNCGKPEQVQVMPPAPSDDLATLSELNDSSLLYEIQKRFGNDQIHTFIGDIFLLVNPFKELPIYSTMVSQMYLSPTGQRSPSLPPHLFSCAERAFHRLFQERKPQNIILSGERGSGKTQASKQIMKYLTSRASSSCTMFDSRLRHAIYIVEAFGHAKTTLNNVSSCLIQYWELQCCQRRKHITGARISTYMLEKSRVVAQPPGQGTFLIFSWLMDGLSSEEKCGLHLNNFCAHRYVSQGMREDVSTAEHSLNKERLAALKHALNVIGFSTLEVENLFVILSAILHIGDIQFTALTEADSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDVIIRRHTIQMAAFYRDLLAKSLYSRLFGFLINTVNCCLQNQDEYKSLQTLDIGILDIFGFEEFQKNEFEQLCVNLTNEKMHHYIQEVLFLQEQTECVQEGVAMETACSPGNQAGVLDFFFQKPSGFFSLLDEESQVIWSGEPNLPRKLQGLLESSNTNAVYSPVKDGNGNVAFKGQGAAFTVMHYAGRVMYEMGGAVERNKDSLSQNLLFVMKTSENVVISHLFQSKLSQTGSLISSYPSFKFGGHKSTLLSKRTASSMVGVNKNYLELSKLLKKKGTSTFLQRLERGEPATAASQLTKSLADITAKLQRGSPHFILCIKPNTSQLPGVFDHFYVSAQLQYLGVLGLVRLFRSGYPVRPSFEDFLSRYEPLASVLLGETKGQAAEERCRLVLQRCKLQGWQIGVHKVFLKYWHVDQLSDLWLQLQRKIVTCQKVIRGFLARQHLLQRMSIKQQEVTSIKSFLQSTEDMALKTYDALVIQNASDIAREHDRLRKEVHTAYHRNRQEEGTKRAEDQGGCRHVHSNSVPVPMVVDSLAQALTGPSTRPPSLHSVFSMDDSTGLPSPRKQPPPKPKRDPNTRLSASYEAVSACLSAAKDAAGEALTRPRPHSDDYSTMKKIPPRKPKRSPHTKLSGSYEEIWGPPRPSGTMGQGGRHQAPGTLSVQWARPDSVPQCTPQLPLHLPLPQGDYDDDAEPVYIEMVGNAARAGGSETDSPDQGESVYEEMKYILPEEGCGLGMLTFLPASPPLFLETRKAIILEAAEGNCQPSKDTCDIPPPFPNLLPHRPPLLVFPPTPVTRSPASDESPLTPLEVKKLPVLETNLKYPVQSEGSSPLSPQYSKAQKGDNDQLASPGFPVFNGPSRISPPATPPPPPGPPPAPCGPPPAPCGPPPAPCGPPPAPCGPPPAPCGPPPAPCGAASASCGVAPAPCRPPTHFAFPPESVLVTAAKALTNSDLPRTQPKPSSAPVPGPCSSFVKAPYSPGKTARADLRKTSSTFSPPSPYSPPNSRPLSSPLDELASLFNSGRSVLRRSAVGRRIREAEGFETNMNLSSRDEPSSSEMASETQDRNANNHGTQLSSSLSSDVTAENGNPVTNGLAEDDGCSRLCLSGMGTSSFQRNRESHTTQVIHQLRLSENESVALQELLDWRRKLCEAREGWQEALQHPEPRAPPPPPCKKPTLLKKPEGGSCTRLPSQLWDSSM
uniprot
proteins
function
FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development (By similarity). Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis. {ECO:0000250, ECO:0000269|PubMed:21946561}.
uniprot
proteins
mass_dalton
211383
uniprot
proteins
mutagenesis
MUTAGEN 1416; /note="Y->F: Slight reduction of phosphorylation in HEK293T cells. Abolishes phosphorylation in HEK293T cells and neurons; when associated with F-1441."; /evidence="ECO:0000269|PubMed:21946561"; MUTAGEN 1441; /note="Y->F: Slight reduction of phosphorylation in HEK293T cells. Abolishes phosphorylation in HEK293T cells and in neurons; when associated with F-1416."; /evidence="ECO:0000269|PubMed:21946561
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues by FYN upon stimulation with CNTN5. Phosphorylation begins at 14 dpc, reaches a peak during perinatal days in brain, then gradually decreases. {ECO:0000269|PubMed:21946561}.
uniprot
proteins
protein_family
Myosin family; NYAP family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
21946561
uniprot
proteins
sequence_length
1919
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9ERC1}. Note=Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells. {ECO:0000250|UniProtKB:Q9ERC1}.
uniprot
proteins