Fnta
entrez
25318
canonical
uniprot
Q04631
canonical
ensembl
ENSRNOG00000014462
resolver
ensp
ENSRNOP00000019594
resolver
genesymbol
Fnta
resolver
uniprot
F7FMZ5
resolver
uniprot_entry
F7FMZ5_RAT
resolver
uniprot_entry
FNTA_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Activated by the AGRIN-induced phosphorylation which is mediated by MUSK. {ECO:0000250|UniProtKB:Q61239}.
uniprot
proteins
amino_acid_sequence
MAATEGVGESAPGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPSPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYIIAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSRESDIPASV
uniprot
proteins
ec_number
2.5.1.58
uniprot
proteins
ec_number
2.5.1.59
uniprot
proteins
function
FUNCTION: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. {ECO:0000269|PubMed:14609943, ECO:0000269|PubMed:18844669, ECO:0000269|PubMed:19219049, ECO:0000269|PubMed:22963166}.
uniprot
proteins
mass_dalton
44049
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA (By similarity). {ECO:0000250|UniProtKB:Q61239}.
uniprot
proteins
protein_family
Protein prenyltransferase subunit alpha family
uniprot
proteins
pubmed
10377218
uniprot
proteins
pubmed
10673434
uniprot
proteins
pubmed
11687658
uniprot
proteins
pubmed
12374986
uniprot
proteins
pubmed
12657282
uniprot
proteins
pubmed
12667062
uniprot
proteins
pubmed
14609943
uniprot
proteins
pubmed
15170324
uniprot
proteins
pubmed
15451670
uniprot
proteins
pubmed
1763049
uniprot
proteins
pubmed
18844669
uniprot
proteins
pubmed
19219049
uniprot
proteins
pubmed
22963166
uniprot
proteins
pubmed
9065406
uniprot
proteins
pubmed
9609683
uniprot
proteins
pubmed
9657673
uniprot
proteins
pubmed
9843427
uniprot
proteins
sequence_length
377
uniprot
proteins