Idh2
entrez
269951
canonical
uniprot
P54071
canonical
ensembl
ENSMUSG00000030541
resolver
ensp
ENSMUSP00000103007
resolver
ensp
ENSMUSP00000268656
resolver
enst
ENSMUST00000107384
resolver
genesymbol
Idh2
resolver
uniprot
Q8C2R9
resolver
uniprot
Q9EQK1
resolver
uniprot_entry
IDHP_MOUSE
resolver
uniprot_sec
Q8C2R9
resolver
uniprot_sec
Q9EQK1
resolver
amino_acid_sequence
MAGYLRAVSSLCRASGSARTWAPAALTVPSWPEQPRRHYAEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ
uniprot
proteins
ec_number
1.1.1.42
uniprot
proteins
function
FUNCTION: Plays a role in intermediary metabolism and energy production (PubMed:8867815). It may tightly associate or interact with the pyruvate dehydrogenase complex (PubMed:8867815). {ECO:0000269|PubMed:8867815}.
uniprot
proteins
mass_dalton
50906
uniprot
proteins
post_translational_modification
PTM: Acetylation at Lys-413 dramatically reduces catalytic activity. Deacetylated by SIRT3 (By similarity). {ECO:0000250|UniProtKB:P48735}.
uniprot
proteins
protein_family
Isocitrate and isopropylmalate dehydrogenases family
uniprot
proteins
pubmed
11278619
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
8867815
uniprot
proteins
sequence_length
452
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:8867815}.
uniprot
proteins