HSBP1
entrez
3281
canonical
uniprot
O75506
canonical
ensembl
ENSG00000230989
resolver
ensp
ENSP00000392896
resolver
ensp
ENSP00000458007
resolver
ensp
ENSP00000629517
resolver
ensp
ENSP00000629518
resolver
ensp
ENSP00000629519
resolver
enst
ENST00000433866
resolver
enst
ENST00000570259
resolver
enst
ENST00000959458
resolver
enst
ENST00000959459
resolver
enst
ENST00000959460
resolver
genesymbol
HSBP1
resolver
genesymbol_syn
HSF1BP
resolver
hgnc
HGNC:5203
resolver
uniprot
Q53XA8
resolver
uniprot
Q7Z5Z3
resolver
uniprot_entry
HSBP1_HUMAN
resolver
uniprot_sec
Q53XA8
resolver
uniprot_sec
Q7Z5Z3
resolver
amino_acid_sequence
MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELESENKIPATQKS
uniprot
proteins
function
FUNCTION: Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process.
uniprot
proteins
mass_dalton
8544
uniprot
proteins
mutagenesis
MUTAGEN 16; /note="V->K: Loss of interaction with HSF1; in association with K-19."; /evidence="ECO:0000269|PubMed:9649501"; MUTAGEN 19; /note="L->K: Loss of interaction with HSF1; in association with K-16."; /evidence="ECO:0000269|PubMed:9649501"; MUTAGEN 45; /note="I->K: Loss of interaction with HSF1; in association with K-48."; /evidence="ECO:0000269|PubMed:9649501"; MUTAGEN 48; /note="L->K: Loss of interaction with HSF1; in association with K-45."; /evidence="ECO:0000269|PubMed:9649501
uniprot
proteins
protein_family
HSBP1 family
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18767159
uniprot
proteins
pubmed
9649501
uniprot
proteins
sequence_length
76
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins