BATF3
entrez
55509
canonical
uniprot
Q9NR55
canonical
ensembl
ENSG00000123685
resolver
ensp
ENSP00000243440
resolver
enst
ENST00000243440
resolver
genesymbol
BATF3
resolver
genesymbol_syn
SNFT
resolver
hgnc
HGNC:28915
resolver
uniprot_entry
BATF3_HUMAN
resolver
amino_acid_sequence
MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKADKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDPVAGCLPR
uniprot
proteins
function
FUNCTION: AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. {ECO:0000250, ECO:0000269|PubMed:10878360, ECO:0000269|PubMed:12087103, ECO:0000269|PubMed:15467742}.
uniprot
proteins
mass_dalton
14468
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
pubmed
10878360
uniprot
proteins
pubmed
12087103
uniprot
proteins
pubmed
15467742
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12087103}.
uniprot
proteins