Ap4b1
entrez
67489
canonical
uniprot
Q9WV76
canonical
ensembl
ENSMUSG00000032952
resolver
ensp
ENSMUSP00000044262
resolver
ensp
ENSMUSP00000075904
resolver
ensp
ENSMUSP00000102436
resolver
ensp
ENSMUSP00000224389
resolver
ensp
ENSMUSP00000224395
resolver
enst
ENSMUST00000047285
resolver
enst
ENSMUST00000076599
resolver
enst
ENSMUST00000106823
resolver
genesymbol
Ap4b1
resolver
uniprot
B0V3P2
resolver
uniprot
B0V3P4
resolver
uniprot
Q7TND3
resolver
uniprot
Q9D8S2
resolver
uniprot_entry
AP4B1_MOUSE
resolver
uniprot_entry
B0V3P4_MOUSE
resolver
uniprot_entry
Q7TND3_MOUSE
resolver
uniprot_entry
Q9D8S2_MOUSE
resolver
uniprot_sec
B0V3P2
resolver
amino_acid_sequence
MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRHMTQGLDMSDVFMEMVKASATVDIVQKKLVYLYMGTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPVVNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSYLKSSSTGVVMGATKLFLILAKKFPHVQTDVLVRVKGPLLAACSSESRELCFAALCHVRQVLHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEELRGYCTDVAADFAQAAIFAIGSIAKTYTDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEENIQDSEGKQALIWLLGVHGEKIPNAPYVLEDFVDNVKSETFPAVKMELLTALMRLVLSRPAECQDMLGRLLHYCIEEEKDMAVRDRGLFYYRLLLVGIDKVKQILCSPKSDPSLGLLEDQPERPVNSWASDFNTLAPVYGRAHWATISKCQQVERHRLELPHNASFATSGHLISEENKEGAQEPDSDTLMLVPNLQLTAEYFEKTWLSLRVSYQQVFPWQGEVQPDTLQMALKVVNIQTIAMSRAGAQPWKAYLSAQDDTGGLFLAELLLKPENSEMQISVKQSKARTESLHGFVSVLETVIGTVGDIKS
uniprot
proteins
function
FUNCTION: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (PubMed:18341993). AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (By similarity). {ECO:0000250|UniProtKB:Q9Y6B7, ECO:0000269|PubMed:18341993}.
uniprot
proteins
mass_dalton
82976
uniprot
proteins
protein_family
Adaptor complexes large subunit family
uniprot
proteins
pubmed
10436028
uniprot
proteins
pubmed
18341993
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
738
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q9Y6B7}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9Y6B7}.
uniprot
proteins