Faim2
entrez
246274
canonical
uniprot
O88407
canonical
ensembl
ENSRNOG00000045554
resolver
ensembl
ENSRNOG00055029574
resolver
ensembl
ENSRNOG00060006516
resolver
ensembl
ENSRNOG00065022426
resolver
ensp
ENSRNOP00000064487
resolver
ensp
ENSRNOP00055042207
resolver
ensp
ENSRNOP00060007913
resolver
ensp
ENSRNOP00065030986
resolver
enst
ENSRNOT00000072309
resolver
enst
ENSRNOT00055051238
resolver
enst
ENSRNOT00060010680
resolver
enst
ENSRNOT00065038274
resolver
genesymbol
Faim2
resolver
genesymbol_syn
Lfg
resolver
genesymbol_syn
Lfg2
resolver
genesymbol_syn
Nmp35
resolver
uniprot_entry
LFG2_RAT
resolver
amino_acid_sequence
MTQGKLSVANKAPGTEGQQQANGEKKDAPAVPSAPPSYEEATSGEGLKAGAFPQGPTAVPLHPSWAYVDPSSSSGYEGGFPAGHHELFSTFSWDDQKVRQLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTIFSFQTKFDFTSCHGVLFVLLMTLFFSGLLLAILLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE
uniprot
proteins
function
FUNCTION: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. Plays a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
35036
uniprot
proteins
protein_family
BI1 family
uniprot
proteins
protein_family
LFG subfamily
uniprot
proteins
pubmed
12414123
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9698393
uniprot
proteins
sequence_length
316
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12414123}; Multi-pass membrane protein {ECO:0000269|PubMed:12414123}. Membrane raft {ECO:0000250}. Postsynaptic cell membrane {ECO:0000269|PubMed:12414123}.
uniprot
proteins
transmembrane_region
TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 138..158; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 251..271; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 290..310; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins