Hyal2
entrez
15587
canonical
uniprot
O35632
canonical
ensembl
ENSMUSG00000010047
resolver
ensp
ENSMUSP00000010191
resolver
ensp
ENSMUSP00000141280
resolver
ensp
ENSMUSP00000260766
resolver
ensp
ENSMUSP00000260771
resolver
enst
ENSMUST00000010191
resolver
enst
ENSMUST00000195752
resolver
genesymbol
Hyal2
resolver
uniprot
O35631
resolver
uniprot
Q3UZE4
resolver
uniprot
Q99MS9
resolver
uniprot
Q99MT0
resolver
uniprot_entry
HYAL2_MOUSE
resolver
uniprot_entry
Q3UZE4_MOUSE
resolver
uniprot_sec
O35631
resolver
uniprot_sec
Q99MS9
resolver
uniprot_sec
Q99MT0
resolver
amino_acid_sequence
MRAGLGPIITLALVLEVAWAGELKPTAPPIFTGRPFVVAWNVPTQECAPRHKVPLDLRAFDVKATPNEGFFNQNITTFYYDRLGLYPRFDAAGTSVHGGVPQNGSLCAHLPMLKESVERYIQTQEPGGLAVIDWEEWRPVWVRNWQEKDVYRQSSRQLVASRHPDWPSDRVMKQAQYEFEFAARQFMLNTLRYVKAVRPQHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAWLWAESTALFPSVYLDETLASSVHSRNFVSFRVREALRVAHTHHANHALPVYVFTRPTYTRGLTGLSQVDLISTIGESAALGSAGVIFWGDSEDASSMETCQYLKNYLTQLLVPYIVNVSWATQYCSWTQCHGHGRCVRRNPSANTFLHLNASSFRLVPGHTPSEPQLRPEGQLSEADLNYLQKHFRCQCYLGWGGEQCQRNYKGAAGNASRAWAGSHLTSLLGLVAVALTWTL
uniprot
proteins
ec_number
3.2.1.35
uniprot
proteins
function
FUNCTION: Catalyzes hyaluronan degradation into small fragments that are endocytosed and degraded in lysosomes by HYAL1 and exoglycosidases (Probable). Essential for the breakdown of extracellular matrix hyaluronan (PubMed:18772348, PubMed:23172227, PubMed:26515055, PubMed:28081210). {ECO:0000269|PubMed:18772348, ECO:0000269|PubMed:23172227, ECO:0000269|PubMed:26515055, ECO:0000269|PubMed:28081210, ECO:0000305|PubMed:23172227}.
uniprot
proteins
mass_dalton
53618
uniprot
proteins
protein_family
Glycosyl hydrolase 56 family
uniprot
proteins
pubmed
11296287
uniprot
proteins
pubmed
11731268
uniprot
proteins
pubmed
11960552
uniprot
proteins
pubmed
18772348
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
23172227
uniprot
proteins
pubmed
26515055
uniprot
proteins
pubmed
28081210
uniprot
proteins
pubmed
9790770
uniprot
proteins
sequence_length
473
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26515055}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q12891}.
uniprot
proteins