P47226
uniprot
P47226
canonical
amino_acid_sequence
MSATHPTRLGTRTKESNACASQGLVRKPPWANEGEGFELHFWRKICRNCNVVKKSMTVLLSNEEDRKVGRLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKFPSEMNAQGDKVHNCGNRHAPAAVASKDKSAESKKTQYSCYCCKHTTNEGEPAIYAERAGYDKLWHPACFICSTCGELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDHILAGKIYVMVTDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKRMMS
uniprot
proteins
function
FUNCTION: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
47983
uniprot
proteins
protein_family
Prickle / espinas / testin family
uniprot
proteins
pubmed
16033868
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21278383
uniprot
proteins
pubmed
7758969
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21278383}. Cell junction, focal adhesion {ECO:0000250}. Note=Detected along actin stress fibers (By similarity). Detected at the subacrosomal layer in round spermatids. {ECO:0000250}.
uniprot
proteins