TMED3
entrez
23423
canonical
uniprot
Q9Y3Q3
canonical
ensembl
ENSG00000166557
resolver
ensp
ENSP00000299705
resolver
ensp
ENSP00000414983
resolver
ensp
ENSP00000440228
resolver
ensp
ENSP00000446062
resolver
ensp
ENSP00000709651
resolver
enst
ENST00000536821
resolver
enst
ENST00000543455
resolver
genesymbol
TMED3
resolver
genesymbol_syn
C15orf22
resolver
hgnc
HGNC:28889
resolver
uniprot
A0A140VKD1
resolver
uniprot
A8K069
resolver
uniprot
B4DN05
resolver
uniprot
B4E277
resolver
uniprot
F5H4M7
resolver
uniprot
G3V1J9
resolver
uniprot
Q2T9F8
resolver
uniprot_entry
A0A140VKD1_HUMAN
resolver
uniprot_entry
B4E277_HUMAN
resolver
uniprot_entry
F5H4M7_HUMAN
resolver
uniprot_entry
G3V1J9_HUMAN
resolver
uniprot_entry
TMED3_HUMAN
resolver
uniprot_sec
A8K069
resolver
uniprot_sec
B4DN05
resolver
uniprot_sec
Q2T9F8
resolver
amino_acid_sequence
MGSTVPRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS
uniprot
proteins
function
FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. {ECO:0000269|PubMed:10852829}.
uniprot
proteins
mass_dalton
24777
uniprot
proteins
protein_family
EMP24/GP25L family
uniprot
proteins
pubmed
10852829
uniprot
proteins
pubmed
12237308
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
16940185
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
217
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:12237308}; Single-pass type I membrane protein {ECO:0000255}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:10852829, ECO:0000269|PubMed:12237308}; Single-pass type I membrane protein {ECO:0000255}. Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q6AY25}; Single-pass type I membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:10852829}; Single-pass type I membrane protein {ECO:0000255}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000305|PubMed:16940185}; Single-pass type I membrane protein {ECO:0000255}. Note=Probably cycles between compartments of the early secretatory pathway. {ECO:0000269|PubMed:10852829}.
uniprot
proteins
transmembrane_region
TRANSMEM 181..201; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins