MEX3B
entrez
84206
canonical
uniprot
Q6ZN04
canonical
ensembl
ENSG00000183496
resolver
ensp
ENSP00000329918
resolver
genesymbol
MEX3B
resolver
genesymbol_syn
KIAA2009
resolver
genesymbol_syn
RKHD3
resolver
genesymbol_syn
RNF195
resolver
hgnc
HGNC:25297
resolver
uniprot
Q4G0W1
resolver
uniprot
Q8IVG2
resolver
uniprot
Q9H0J0
resolver
uniprot_entry
MEX3B_HUMAN
resolver
uniprot_sec
Q4G0W1
resolver
uniprot_sec
Q8IVG2
resolver
uniprot_sec
Q9H0J0
resolver
amino_acid_sequence
MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS
uniprot
proteins
function
FUNCTION: RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.
uniprot
proteins
mass_dalton
58832
uniprot
proteins
mutagenesis
MUTAGEN 177; /note="G->D: Prevents RNA binding."; /evidence="ECO:0000269|PubMed:17267406
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Ser-462 creates a docking site for 14-3-3, which stabilizes the protein and modulates its ability to bind RNA. {ECO:0000269|PubMed:17267406, ECO:0000269|PubMed:18779327}.
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17267406
uniprot
proteins
pubmed
18779327
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
569
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18779327}. Cytoplasm {ECO:0000269|PubMed:18779327}. Cytoplasm, P-body {ECO:0000269|PubMed:18779327}. Cytoplasmic granule {ECO:0000269|PubMed:18779327}. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3.
uniprot
proteins