Efna3
entrez
13638
canonical
uniprot
O08545
canonical
ensembl
ENSMUSG00000028039
resolver
ensp
ENSMUSP00000029673
resolver
ensp
ENSMUSP00000143539
resolver
enst
ENSMUST00000029673
resolver
enst
ENSMUST00000200436
resolver
genesymbol
Efna3
resolver
genesymbol_syn
Epl3
resolver
genesymbol_syn
Eplg3
resolver
genesymbol_syn
Lerk3
resolver
uniprot
A0A0G2JGE9
resolver
uniprot
O55217
resolver
uniprot
Q08AV0
resolver
uniprot_entry
A0A0G2JGE9_MOUSE
resolver
uniprot_entry
EFNA3_MOUSE
resolver
uniprot_sec
O55217
resolver
uniprot_sec
Q08AV0
resolver
amino_acid_sequence
MAAAPLLLLLLLVPVPLLPLLAQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSSGPGGGAEQYVLYMVNLSGYRTCNASQGSKRWECNRQHASHSPIKFSEKFQRYSAFSLGYEFHAGQEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTLLAS
uniprot
proteins
function
FUNCTION: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. {ECO:0000269|PubMed:9053851}.
uniprot
proteins
mass_dalton
25632
uniprot
proteins
protein_family
Ephrin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
27446912
uniprot
proteins
pubmed
8903354
uniprot
proteins
pubmed
9053851
uniprot
proteins
pubmed
9465306
uniprot
proteins
sequence_length
230
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
uniprot
proteins