Ppt1
entrez
19063
canonical
uniprot
O88531
canonical
ensembl
ENSMUSG00000028657
resolver
ensp
ENSMUSP00000030412
resolver
enst
ENSMUST00000030412
resolver
genesymbol
Ppt1
resolver
genesymbol_syn
Cln1
resolver
genesymbol_syn
Ppt
resolver
uniprot
Q3TEL0
resolver
uniprot
Q3U6J9
resolver
uniprot
Q3U6W3
resolver
uniprot
Q9D681
resolver
uniprot
Q9WTY3
resolver
uniprot_entry
PPT1_MOUSE
resolver
uniprot_entry
Q3TEL0_MOUSE
resolver
uniprot_entry
Q3U6J9_MOUSE
resolver
uniprot_entry
Q3U6W3_MOUSE
resolver
uniprot_sec
Q9D681
resolver
uniprot_sec
Q9WTY3
resolver
amino_acid_sequence
MASSCSRRLLAAALLPWCCAAWALGHLDPPSPPPLVIWHGMGDSCCNPMSMGVIKKMVEKEIPGIYVLSLEIGKNMMEDVENSFFLNVNVQVNMVCQILEKDPKLQQGYNAIGFSQGGQFLRAVAQRCPTPPMMTLISVGGQHQGVFGLPRCPGESSHICDFIRKSLNAGAYSKLVQERLVQAQYWHDPIKESVYRNYSIFLADINQERCVNESYKKNLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQESTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFLK
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
ec_number
3.1.2.22
uniprot
proteins
function
FUNCTION: Has thioesterase activity against fatty acid thioesters with 14 -18 carbons, including palmitoyl-CoA, S-palmitoyl-N-acetylcysteamine, and palmitoylated proteins. In contrast to PPT2, PPT1 can hydrolyze palmitoylated proteins and palmitoylcysteine. {ECO:0000250|UniProtKB:P50897}.
uniprot
proteins
mass_dalton
34490
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000269|PubMed:9685319}.
uniprot
proteins
protein_family
Palmitoyl-protein thioesterase family
uniprot
proteins
pubmed
10231585
uniprot
proteins
pubmed
11717424
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19941651
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9685319
uniprot
proteins
sequence_length
306
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000269|PubMed:19941651, ECO:0000269|PubMed:9685319}. Secreted {ECO:0000269|PubMed:9685319}. Golgi apparatus {ECO:0000250|UniProtKB:P50897}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P50897}.
uniprot
proteins