Glce
entrez
93683
canonical
uniprot
Q9EPS3
canonical
ensembl
ENSMUSG00000032252
resolver
ensp
ENSMUSP00000034785
resolver
ensp
ENSMUSP00000139949
resolver
enst
ENSMUST00000034785
resolver
enst
ENSMUST00000185675
resolver
genesymbol
Glce
resolver
uniprot
Q505E6
resolver
uniprot
Q99MM0
resolver
uniprot_entry
GLCE_MOUSE
resolver
uniprot_sec
Q505E6
resolver
uniprot_sec
Q99MM0
resolver
amino_acid_sequence
MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRHLSSGFRVDGLEKRSAASESNHYANHIAKQQSEEAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIKGRREGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDRNIRPNEWTVPKGCFMASVADKSRSTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKLLTNGSVSVVLETTEKNQLFTVHYVSNTQLIAFRDRDIYYGIGPRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKGGWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDYVFLSSALRATAPYKFPSEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGETLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN
uniprot
proteins
ec_number
5.1.3.17
uniprot
proteins
function
FUNCTION: Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins. {ECO:0000269|PubMed:11274177, ECO:0000269|PubMed:11279150, ECO:0000269|PubMed:16532012, ECO:0000269|PubMed:20208005}.
uniprot
proteins
mass_dalton
70089
uniprot
proteins
pathway_participation
PATHWAY: Glycan metabolism; heparan sulfate biosynthesis. {ECO:0000305|PubMed:11274177, ECO:0000305|PubMed:11279150}.; PATHWAY: Glycan metabolism; heparin biosynthesis. {ECO:0000305|PubMed:11274177, ECO:0000305|PubMed:11279150}.
uniprot
proteins
protein_family
D-glucuronyl C5-epimerase family
uniprot
proteins
pubmed
11274177
uniprot
proteins
pubmed
11279150
uniprot
proteins
pubmed
11687650
uniprot
proteins
pubmed
12788935
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16532012
uniprot
proteins
pubmed
20208005
uniprot
proteins
sequence_length
618
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:11279150}; Single-pass type II membrane protein {ECO:0000269|PubMed:11279150}.
uniprot
proteins
transmembrane_region
TRANSMEM 12..29; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins