PUM3
entrez
9933
canonical
uniprot
Q15397
canonical
ensembl
ENSG00000080608
resolver
ensp
ENSP00000380982
resolver
ensp
ENSP00000531087
resolver
ensp
ENSP00000531093
resolver
ensp
ENSP00000531094
resolver
ensp
ENSP00000531095
resolver
ensp
ENSP00000592264
resolver
ensp
ENSP00000592265
resolver
ensp
ENSP00000592266
resolver
ensp
ENSP00000592268
resolver
ensp
ENSP00000592271
resolver
ensp
ENSP00000592272
resolver
ensp
ENSP00000592274
resolver
ensp
ENSP00000592275
resolver
ensp
ENSP00000592276
resolver
enst
ENST00000397885
resolver
enst
ENST00000861028
resolver
enst
ENST00000861034
resolver
enst
ENST00000861035
resolver
enst
ENST00000861036
resolver
enst
ENST00000922205
resolver
enst
ENST00000922206
resolver
enst
ENST00000922207
resolver
enst
ENST00000922209
resolver
enst
ENST00000922212
resolver
enst
ENST00000922213
resolver
enst
ENST00000922215
resolver
enst
ENST00000922216
resolver
enst
ENST00000922217
resolver
genesymbol
PUM3
resolver
genesymbol_syn
KIAA0020
resolver
genesymbol_syn
PUF-A
resolver
genesymbol_syn
XTP5
resolver
genesymbol_syn
cPERP-C
resolver
hgnc
HGNC:29676
resolver
uniprot
A8K804
resolver
uniprot
Q547G7
resolver
uniprot
Q5SZY9
resolver
uniprot
Q6IB47
resolver
uniprot
Q96B27
resolver
uniprot
Q96L78
resolver
uniprot
Q96L79
resolver
uniprot
Q96L80
resolver
uniprot_entry
PUM3_HUMAN
resolver
uniprot_sec
A8K804
resolver
uniprot_sec
Q547G7
resolver
uniprot_sec
Q5SZY9
resolver
uniprot_sec
Q6IB47
resolver
uniprot_sec
Q96B27
resolver
uniprot_sec
Q96L78
resolver
uniprot_sec
Q96L79
resolver
uniprot_sec
Q96L80
resolver
amino_acid_sequence
MEVKGKKQFTGKSTKTAQEKNRFHKNSDSGSSKTFPTRKVAKEGGPKVTSRNFEKSITKLGKKGVKQFKNKQQGDKSPKNKFQPANKFNKKRKFQPDGRSDESAAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKQMWEILRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCYIQYGNEEQRKQAFEELRDDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHAEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADHRTLDKVLEVQPEKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKLRSEMIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLLSPRDPAHTVREIIEVLQKGDGNAHSKKDTEVRRRELLESISPALLSYLQEHAQEVVLDKSACVLVSDILGSATGDVQPTMNAIASLAATGLHPGGKDGELHIAEHPAGHLVLKWLIEQDKKMKENGREGCFAKTLVEHVGMKNLKSWASVNRGAIILSSLLQSCDLEVANKVKAALKSLIPTLEKTKSTSKGIEILLEKLST
uniprot
proteins
function
FUNCTION: Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351). Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524). Involved in development of the eye and of primordial germ cells (By similarity). {ECO:0000250|UniProtKB:X1WGX5, ECO:0000269|PubMed:21266351, ECO:0000269|PubMed:25512524}.
uniprot
proteins
mass_dalton
73584
uniprot
proteins
pubmed
11148223
uniprot
proteins
pubmed
12429849
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20813266
uniprot
proteins
pubmed
21266351
uniprot
proteins
pubmed
25512524
uniprot
proteins
pubmed
7584026
uniprot
proteins
sequence_length
648
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:21266351, ECO:0000269|Ref.6}. Nucleus, nucleoplasm {ECO:0000269|PubMed:21266351}. Chromosome {ECO:0000269|PubMed:20813266}. Note=Localizes predominantly in the nucleolus with minor punctate signals in the nucleoplasm. {ECO:0000269|PubMed:21266351}.
uniprot
proteins