Herpud1
entrez
64209
canonical
uniprot
Q9JJK5
canonical
ensembl
ENSMUSG00000031770
resolver
ensp
ENSMUSP00000034220
resolver
ensp
ENSMUSP00000124201
resolver
enst
ENSMUST00000034220
resolver
enst
ENSMUST00000161576
resolver
genesymbol
Herpud1
resolver
uniprot
F8WIK1
resolver
uniprot
Q3TMN9
resolver
uniprot
Q8C4N0
resolver
uniprot_entry
F8WIK1_MOUSE
resolver
uniprot_entry
HERP1_MOUSE
resolver
uniprot_entry
Q3TMN9_MOUSE
resolver
uniprot_entry
Q8C4N0_MOUSE
resolver
amino_acid_sequence
MEPEPQPEPVTLLVKSPNQRHRDLELSGDRSWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVKNPSKMPETSTKGAESTEQPDNSNQTQHPGDSSSDGLRQREVLRNLSPSGWENISRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGTFVPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGGPRDAANQDPNNNLQGGMDPEMEDPNRLPPDREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN
uniprot
proteins
function
FUNCTION: Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway. {ECO:0000250|UniProtKB:Q15011}.
uniprot
proteins
mass_dalton
43907
uniprot
proteins
pubmed
10922362
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
391
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 264..284; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 290..310; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins