SPACA6
entrez
147650
canonical
uniprot
W5XKT8
canonical
ensembl
ENSG00000182310
resolver
ensp
ENSP00000490829
resolver
ensp
ENSP00000518379
resolver
enst
ENST00000710615
resolver
genesymbol
SPACA6
resolver
genesymbol_syn
SPACA6P
resolver
hgnc
HGNC:27113
resolver
uniprot
A0AA34QVJ1
resolver
uniprot
C0H5Y6
resolver
uniprot
Q6UWG3
resolver
uniprot_entry
A0AA34QVJ1_HUMAN
resolver
uniprot_entry
SACA6_HUMAN
resolver
uniprot_sec
C0H5Y6
resolver
uniprot_sec
Q6UWG3
resolver
amino_acid_sequence
MALLALASAVPSALLALAVFRVPAWACLLCFTTYSERLRICQMFVGMRSPKLEECEEAFTAAFQGLSDTEINYDERSHLHDTFTQMTHALQELAAAQGSFEVAFPDAAEKMKKVITQLKEAQACIPPCGLQEFARRFLCSGCYSRVCDLPLDCPVQDVTVTRGDQAMFSCIVNFQLPKEEITYSWKFAGGGLRTQDLSYFRDMPRAEGYLARIRPAQLTHRGTFSCVIKQDQRPLARLYFFLNVTGPPPRAETELQASFREVLRWAPRDAELIEPWRPSLGELLARPEALTPSNLFLLAVLGALASASATVLAWMFFRWYCSGN
uniprot
proteins
function
FUNCTION: Sperm protein required for fusion of sperm with the egg membrane during fertilization (By similarity). May regulate the expression of sperm surface protein DCST2 (By similarity). {ECO:0000250|UniProtKB:A0A8M9PDM1, ECO:0000250|UniProtKB:E9Q8Q8}.
uniprot
proteins
mass_dalton
36333
uniprot
proteins
protein_family
SPACA6 family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24275887
uniprot
proteins
pubmed
32210282
uniprot
proteins
pubmed
36115925
uniprot
proteins
pubmed
39423812
uniprot
proteins
sequence_length
324
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000269|PubMed:32210282}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 296..316; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins