NOBOX
entrez
135935
canonical
uniprot
O60393
canonical
ensembl
ENSG00000106410
resolver
ensp
ENSP00000495343
resolver
ensp
ENSP00000496732
resolver
enst
ENST00000645489
resolver
genesymbol
NOBOX
resolver
hgnc
HGNC:22448
resolver
uniprot
A0A2R8Y8C8
resolver
uniprot
A6NCD3
resolver
uniprot
A8MZN5
resolver
uniprot_entry
A0A2R8Y8C8_HUMAN
resolver
uniprot_entry
NOBOX_HUMAN
resolver
uniprot_sec
A6NCD3
resolver
uniprot_sec
A8MZN5
resolver
amino_acid_sequence
MALLLTLTSPDLEGTWDTRDKDGFKAQEGPPLAVPEFPVCGLYRIYGVCGSFSSFFIIRCSLCALETLKSPQHDPLEIPEQSLKLIPLVSGKRELTRGQKAGEKPLAAGPGEEELLRGSAPHAQDTQSEELPPSCTISGEKKPPAVSGEATGADAGRLCPPPRSRAPHKDRTLARSRPQTQGEDCSLPVGEVKIGKRSYSPAPGKQKKPNAMGLAPTSSPGAPNSARATHNPVPCGSGRGPCHLANLLSTLAQSNQNRDHKQGPPEVTCQIRKKTRTLYRSDQLEELEKIFQEDHYPDSDKRREIAQTVGVTPQRIMVKGAGSLVAGWSGGGPTIETLELQSERSAVAWVWFQNRRAKWRKMEKLNGKESKDNPAAPGPASSQCSSAAEILPAVPMEPKPDPFPQESPLDTFPEPPMLLTSDQTLAPTQPSEGAQRVVTPPLFSPPPVRRADLPFPLGPVHTPQLMPLLMDVAGSDSSHKDGPCGSWGTSITLPPPCSYLEELEPQDYQQSNQPGPFQFSQAPQPPLFQSPQPKLPYLPTFPFSMPSSLTLPPPEDSLFMFPCGPSGGTSQGYCPGASSGQILMQPPAGNIGTASWSDPCLPELPFPGPFCPQALGHPPGGDGYFPDLFPTPCPQALGRQPSSALSWMPEGARPGTGPLLSKAKEEPPAASLDQPSALEEARGDDKNSHVP
uniprot
proteins
disease_involvement
DISEASE: Premature ovarian failure 5 (POF5) [MIM:611548]: An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. {ECO:0000269|PubMed:17701902, ECO:0000269|PubMed:21837770, ECO:0000269|PubMed:25514101, ECO:0000269|PubMed:27798098}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Transcription factor which may play a role in oogenesis. Binds preferentially to the DNA sequences 5'-TAATTG-3', 5'-TAGTTG-3' and 5'-TAATTA-3'. {ECO:0000269|PubMed:25514101, ECO:0000269|PubMed:27798098}.
uniprot
proteins
mass_dalton
73906
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
16597639
uniprot
proteins
pubmed
17701902
uniprot
proteins
pubmed
21837770
uniprot
proteins
pubmed
25514101
uniprot
proteins
pubmed
27798098
uniprot
proteins
sequence_length
691
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:27798098}.
uniprot
proteins