Akirin1
entrez
68050
canonical
uniprot
Q99LF1
canonical
ensembl
ENSMUSG00000023075
resolver
ensp
ENSMUSP00000099696
resolver
enst
ENSMUST00000102636
resolver
genesymbol
Akirin1
resolver
genesymbol_syn
Mighty
resolver
uniprot
Q9JJB7
resolver
uniprot_entry
AKIR1_MOUSE
resolver
uniprot_sec
Q9JJB7
resolver
amino_acid_sequence
MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPPDAEPPPLQMQTPPASLQQPAPPGSERRLPTPEQIFQNIKQEYNRYQRWRHLEVVLSQSEACTSETQPSSSALTAPGSPGAFWMKKDQPTFTLRQVGIICERLLKDYEDKVREEYEQILSTKLAEQYESFVKFTHDQIMRRYGTRPTSYVS
uniprot
proteins
function
FUNCTION: Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development (PubMed:18255059, PubMed:19406121, PubMed:30746755). Functions as a signal transducer for MSTN during skeletal muscle regeneration and myogenesis (PubMed:18255059, PubMed:19406121). May regulate chemotaxis of both macrophages and myoblasts by reorganising actin cytoskeleton, leading to more efficient lamellipodia formation via a PI3 kinase dependent pathway (PubMed:19406121). In contrast to AKIRIN2, not involved in nuclear import of proteasomes (By similarity). {ECO:0000250|UniProtKB:Q9H9L7, ECO:0000269|PubMed:18255059, ECO:0000269|PubMed:19406121, ECO:0000269|PubMed:30746755}.
uniprot
proteins
mass_dalton
21676
uniprot
proteins
protein_family
Akirin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18066067
uniprot
proteins
pubmed
18255059
uniprot
proteins
pubmed
19406121
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23516508
uniprot
proteins
pubmed
30746755
uniprot
proteins
sequence_length
191
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9H9L7}.
uniprot
proteins