Apoc1
entrez
11812
canonical
uniprot
P34928
canonical
ensembl
ENSMUSG00000040564
resolver
ensp
ENSMUSP00000045571
resolver
ensp
ENSMUSP00000104091
resolver
enst
ENSMUST00000045035
resolver
enst
ENSMUST00000108451
resolver
genesymbol
Apoc1
resolver
uniprot
Q505B2
resolver
uniprot_entry
APOC1_MOUSE
resolver
uniprot_sec
Q505B2
resolver
amino_acid_sequence
MRLFIALPVLIVVVAMTLEGPAPAQAAPDLSGTLESIPDKLKEFGNTLEDKARAAIEHIKQKEILTKTRAWFSEAFGKVKEKLKTTFS
uniprot
proteins
function
FUNCTION: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein (By similarity). Binds free fatty acids and reduces their intracellular esterification. {ECO:0000250|UniProtKB:P02654, ECO:0000250|UniProtKB:P33047, ECO:0000269|PubMed:17339654}.
uniprot
proteins
mass_dalton
9696
uniprot
proteins
protein_family
Apolipoprotein C1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16876491
uniprot
proteins
pubmed
17339654
uniprot
proteins
pubmed
8276416
uniprot
proteins
sequence_length
88
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P02654}.
uniprot
proteins