B3galnt2
entrez
97884
canonical
uniprot
Q8BG28
canonical
ensembl
ENSMUSG00000039242
resolver
ensp
ENSMUSP00000097336
resolver
ensp
ENSMUSP00000152397
resolver
ensp
ENSMUSP00000152755
resolver
genesymbol
B3galnt2
resolver
uniprot
Q5U4F9
resolver
uniprot
Q8BXL0
resolver
uniprot_entry
B3GL2_MOUSE
resolver
uniprot_sec
Q5U4F9
resolver
uniprot_sec
Q8BXL0
resolver
amino_acid_sequence
MRNWLVLLCPCVLGAALHLWHLWLRSPPDPHNTGPSAADQSALFPHWKFSHYDVVVGVLSARNNHELRNVIRNTWLKNLLHHPTLSQRVLVKFIIGARGCEVPVEDREDPYSCRLLNITNPVLNQEIEAFSFPEDASSSRLSEDRVVSVSFRVLYPIVITSLGVFYDASDVGFQRNITVKLYQTEQEEALFIARFSPPSCGVQVNKLWYKPVEQFILPESFEGTIVWESQDLHGLVSRNLHRVTVNDGGGVLRVLAAGEGALPHEFMEGVEGVAGGFIYTVQEGDALLRSLYSRPQRLADHIQDLQVEDALLQEESSVHDDIVFVDVVDTYRNVPAKLLNFYRWTVESTSFDLLLKTDDDCYIDLEAVFNRIAQKNLDGPNFWWGNFRLNWAVDRTGKWQELEYPSPAYPAFACGSGYVISKDIVDWLAGNSRRLKTYQGEDVSMGIWMAAIGPKRHQDSLWLCEKTCETGMLSSPQYSPEELSKLWELKELCGDPCQCEAKVR
uniprot
proteins
ec_number
2.4.1.313
uniprot
proteins
function
FUNCTION: Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
57219
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
14724282
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
504
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 4..24; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins