BBOF1
entrez
80127
canonical
uniprot
Q8ND07
canonical
ensembl
ENSG00000119636
resolver
ensp
ENSP00000377577
resolver
ensp
ENSP00000571204
resolver
ensp
ENSP00000571205
resolver
ensp
ENSP00000722848
resolver
ensp
ENSP00000722851
resolver
enst
ENST00000394009
resolver
genesymbol
BBOF1
resolver
genesymbol_syn
C14orf45
resolver
genesymbol_syn
CCDC176
resolver
hgnc
HGNC:19855
resolver
uniprot
Q0P604
resolver
uniprot
Q9H5P8
resolver
uniprot_entry
BBOF1_HUMAN
resolver
uniprot_sec
Q0P604
resolver
uniprot_sec
Q9H5P8
resolver
amino_acid_sequence
MPSKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRILAKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVERFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVNQDLLEAEKWTHIEGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQSSRPPVPDYVVSDSGETKEFGDESKLQDKIFITQQIAISDSSGEVVLPTIPKEPQESDTGTF
uniprot
proteins
function
FUNCTION: Plays an essential role in sperm motility and male fertility by stabilizing the sperm flagellar axonemal structure. May be required for the stability of ODF2 and MANS1 proteins. Dispensable for the assembly and function of motile cilia. {ECO:0000250|UniProtKB:Q3V079}.
uniprot
proteins
mass_dalton
61987
uniprot
proteins
protein_family
BBOF1 family
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
529
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A0JMY4}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q3V079}. Note=Localizes to a polar structure adjacent to the basal body. {ECO:0000250|UniProtKB:A0JMY4}.
uniprot
proteins