Q5U301
uniprot
Q5U301
canonical
amino_acid_sequence
MEIGVSVAECKSVPGITSTPHSKDHSSPFYSPSHNGLLTDHHESLDNDVAREIQYLDEVLEANCCDSSVDGTYNGISSPEPGAAILVSSLGSPAHSATKVEPIEKASGRQLPPHIELSRSPSDSMAEGERANGHSTDQPQDMLGNSLQAPASPSSSTSSHCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEEDEHEKEQFCIRKVRPSEEMIELEKERRELIRSQAVKKNPGIAAKWWNPPQKKTIEEQLDEEHLESHRKYKERKEKRAQQEQLQLQQQQQQQLQQLQQLQQQQQQQLSTSQLCTAPAAHEHLDSIEHTKEDVVTEQIDFSAARKQFQQMENSRQTLAKGQSTPRLFSIKPFYKPLGSINSDKPPTILRPATIGGTVEDSSTQAAKEQKALCVSESQSAGAGTGNAATQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDEDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETPNALQENSLADFSLPQTPQTDNPSEGREGVSKSFSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDKAEVHTSKEGSEQQEPGAMVEEAGSQAPGSEKPQGMFAPPQVSSPVQEKRDVLPKILPGEDKTLREKGPSQPPTAVQPSGPVNMKETRPEGGYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVRQSTPSPRAQNAPSLPSRTTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGAQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE
uniprot
proteins
function
FUNCTION: Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. Binds to and modulates the structure of the actin cytoskeleton. {ECO:0000250|UniProtKB:O54931}.
uniprot
proteins
mass_dalton
95941
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641100
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
870
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:O54931}; Lipid-anchor, GPI-like-anchor {ECO:0000250|UniProtKB:O54931}; Cytoplasmic side {ECO:0000250|UniProtKB:O54931}. Note=Accumulates near the inner, apical surface of highly polarized epithelium in tubules of nephrons. {ECO:0000250|UniProtKB:O54931}.
uniprot
proteins