Viral immunoevasion
cv_term_accession
KW-0899
canonical
uniprot_keyword
KW-0899
canonical
name
Viral immunoevasion
uniprot
synonym
Immunoevasin
uniprot
synonym
Viral host defense evasion
uniprot
synonym
Viral immune evasion
uniprot
definition
Viral protein involved in evading host innate and adaptive immune responses, allowing optimized viral replication, propagation, or persistence in the host. The protein allows viruses to avoid/escape immune detection or neutralize/inactivate the host immune defenses to ensure virus survival within its host. The innate immune system is a non-specific defense system found in all cellular organisms. In metazoans and plants, it includes the intracellular pattern recognition receptors (PRRs) that detect pathogen-associated molecular patterns (PAMPs). In plants and invertebrates, it includes the RNA interference (RNAi) system. Plants also have effector-triggered immunity (ETI). In metazoans, it includes the cell-dependent mechanisms (e.g. phagocytes) or secreted factors. Bacteria and archaea have an innate immune system relying on various systems (e.g. the restriction-modification system, Pycsar). The adaptive (or acquired) immune system is a specific defense. In vertebrates, it is mediated by T and B lymphocytes expressing specific receptors. Bacteria and archaea have adaptive immunity, the CRISPR-Cas system.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords