Dok4
entrez
114255
canonical
uniprot
Q99KE3
canonical
ensembl
ENSMUSG00000040631
resolver
ensp
ENSMUSP00000043554
resolver
ensp
ENSMUSP00000148355
resolver
ensp
ENSMUSP00000270495
resolver
ensp
ENSMUSP00000270497
resolver
enst
ENSMUST00000046461
resolver
enst
ENSMUST00000212810
resolver
genesymbol
Dok4
resolver
uniprot
Q3U0X3
resolver
uniprot_entry
DOK4_MOUSE
resolver
uniprot_sec
Q3U0X3
resolver
amino_acid_sequence
MATNFNDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITGSQNIAEASSYGESYGAAQASSETDLLNRFILLKPKPSQEDSSEAKTPAQ
uniprot
proteins
function
FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37040
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues in response to insulin, IGF1 or RET stimulation. {ECO:0000250}.
uniprot
proteins
protein_family
DOK family
uniprot
proteins
protein_family
Type B subfamily
uniprot
proteins
pubmed
11470823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
325
uniprot
proteins