Acsm5
entrez
361637
canonical
uniprot
Q6AYT9
canonical
ensembl
ENSRNOG00000031211
resolver
ensp
ENSRNOP00000047613
resolver
enst
ENSRNOT00000046025
resolver
genesymbol
Acsm5
resolver
genesymbol_syn
Macs3
resolver
uniprot_entry
ACSM5_RAT
resolver
amino_acid_sequence
MRLWLRGLVYQARRSSWGVFRIHTQPPPPPIPEVVATWEAISLGKRPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTFEELGKQSRKAANILEGACGLKPGDRLMLVLPRLPEWWLTIVACMRTGVVMIPGISQLTQKDLKYRLQAARVKSIITSDALAPHVDAISADCPSLQSRLLVSDTSRPGWINFRELLRVASPEHNCLRTRSGDSMAIYFTSGTTGTPKMVEHSQCSYGLGFVASGRRLMALTESDIFWNTTDTGWVKAAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRLLVQEDLTRYKFQCLRHCLAGGEALNSDVRDKWKNQTGLEIHEGYGQSETVLICGNFRGSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFNCYLDNPEKTAASEQGDFYITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYVSHDPEALTRELQEHVKTVTAPYKYPRKVAFISELPKTVSGKILRSKLRNQEWGR
uniprot
proteins
ec_number
6.2.1.2
uniprot
proteins
function
FUNCTION: Acyl-CoA synthetase that catalyzes the ATP-dependent activation of fatty acids to their corresponding acyl-CoA thioesters, the first committed step in fatty acid metabolism (By similarity). Negatively regulates lipid accumulation via inhibition of FABP4-PPARgamma signaling (By similarity). {ECO:0000250|UniProtKB:Q08AH1, ECO:0000250|UniProtKB:Q6NUN0}.
uniprot
proteins
mass_dalton
64623
uniprot
proteins
protein_family
ATP-dependent AMP-binding enzyme family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
578
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q91VA0}.
uniprot
proteins