Haus8
entrez
76478
canonical
uniprot
Q99L00
canonical
ensembl
ENSMUSG00000035439
resolver
ensp
ENSMUSP00000040802
resolver
ensp
ENSMUSP00000105698
resolver
ensp
ENSMUSP00000246515
resolver
genesymbol
Haus8
resolver
genesymbol_syn
Hice1
resolver
uniprot
Q9CWT4
resolver
uniprot_entry
HAUS8_MOUSE
resolver
uniprot_sec
Q9CWT4
resolver
amino_acid_sequence
MADSSERDAGKSAAAGACAVPKTKGRRVQGRRVVESRYLQYDKKAKKVSGAAKEEKPPEGRKASTVPRSREESQVMGTGNLQSTMLEGHGMNPPDLDLSAIDDKILSRKASWPDREMTDKAKSTSFISCDKKRILRKKRRDLQETMDMMESQTLLMTLLSVKMENNLALLEERAEKDLAAMCHEKERLQRQALELRRQLLLRQKHQELAATLDAQIEVLSPLQPVLERFKEEYMTLGRALDTTRHELPMQAVHMEGSGQELLDDLEPALRITLQLLGDLSICSPYATAQVQGASAQEPGASTQLSCLLKELKGLVTEKDLELRRLVSQVVELSSQASKEAALMNQEVWEEAEGALTSSQWYFSPDACRDDSPS
uniprot
proteins
function
FUNCTION: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000250}.
uniprot
proteins
mass_dalton
41653
uniprot
proteins
protein_family
HAUS8 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BT25}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9BT25}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9BT25}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q9BT25}. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively. Localizes to mitotic spindle microtubules (By similarity). {ECO:0000250|UniProtKB:Q9BT25}.
uniprot
proteins