PCMT1
entrez
5110
canonical
uniprot
P22061
canonical
ensembl
ENSG00000120265
resolver
ensp
ENSP00000356350
resolver
ensp
ENSP00000356354
resolver
ensp
ENSP00000420813
resolver
ensp
ENSP00000438247
resolver
enst
ENST00000367380
resolver
enst
ENST00000544496
resolver
genesymbol
PCMT1
resolver
hgnc
HGNC:8728
resolver
uniprot
A0A384MDK7
resolver
uniprot
A0A3F2YNX8
resolver
uniprot
A8K109
resolver
uniprot
B7Z972
resolver
uniprot
F6S8N6
resolver
uniprot
J3KP72
resolver
uniprot
Q14661
resolver
uniprot
Q16556
resolver
uniprot
Q5VYC1
resolver
uniprot
Q5VYC2
resolver
uniprot
Q93061
resolver
uniprot
Q96II9
resolver
uniprot
Q99625
resolver
uniprot
Q9BQV7
resolver
uniprot
Q9BQV8
resolver
uniprot
Q9NP03
resolver
uniprot_entry
A0A384MDK7_HUMAN
resolver
uniprot_entry
A0A3F2YNX8_HUMAN
resolver
uniprot_entry
B7Z972_HUMAN
resolver
uniprot_entry
F6S8N6_HUMAN
resolver
uniprot_entry
PIMT_HUMAN
resolver
uniprot_sec
A8K109
resolver
uniprot_sec
J3KP72
resolver
uniprot_sec
Q14661
resolver
uniprot_sec
Q16556
resolver
uniprot_sec
Q5VYC1
resolver
uniprot_sec
Q5VYC2
resolver
uniprot_sec
Q93061
resolver
uniprot_sec
Q96II9
resolver
uniprot_sec
Q99625
resolver
uniprot_sec
Q9BQV7
resolver
uniprot_sec
Q9BQV8
resolver
uniprot_sec
Q9NP03
resolver
amino_acid_sequence
MAWKSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKCNPYMDSPQSIGFQATISAPHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSVNNVRKDDPTLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSIKMKPLMGVIYVPLTDKEKQWSRWK
uniprot
proteins
ec_number
2.1.1.77
uniprot
proteins
function
FUNCTION: Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins (PubMed:3167043, PubMed:6469980). Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin C-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein (By similarity). {ECO:0000250|UniProtKB:P23506, ECO:0000269|PubMed:3167043, ECO:0000269|PubMed:6469980}.
uniprot
proteins
mass_dalton
24636
uniprot
proteins
protein_family
L-isoaspartyl/D-aspartyl protein methyltransferase family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
10496068
uniprot
proteins
pubmed
11792715
uniprot
proteins
pubmed
11847284
uniprot
proteins
pubmed
1339271
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1998518
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
2684970
uniprot
proteins
pubmed
3167043
uniprot
proteins
pubmed
6469980
uniprot
proteins
pubmed
7592526
uniprot
proteins
pubmed
8074695
uniprot
proteins
pubmed
8914929
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:3167043}.
uniprot
proteins