Mroh2b
entrez
223825
canonical
uniprot
Q7M6Y6
canonical
ensembl
ENSMUSG00000022155
resolver
ensp
ENSMUSP00000036148
resolver
genesymbol
Mroh2b
resolver
genesymbol_syn
Heatr7b2
resolver
uniprot
A0A096XFP7
resolver
uniprot
A0A096XFP8
resolver
uniprot_entry
MRO2B_MOUSE
resolver
uniprot_sec
A0A096XFP7
resolver
uniprot_sec
A0A096XFP8
resolver
amino_acid_sequence
MEEYGDMFGDINLTIGMLSKEDNISKEDIYCHLTSFIQNTDIMDDAIVQRLIYYTSKDMRDEEIPRELRMLAGEVLVSLAAHDFNSVMYEVQSNFRILELPNEFVVLALAELATSYVSQSIPFMMMTLLTMQTMLRLVEDENMRQTFCIALENFSKSIYKYVNHWKDFPYPKLDANRLSDKIFMLFRYIMEKWAPQASPMHALAIIKAHGPTVSLLLHREDFCEFALSQISWLLLQYRDKENDFYITQSLKQILTAAVLYDIALPKNLRRSVLSSLLHQICKVPEPPIKENKLEASSCFLILAHANPVDLLDFFDEQIRSTNEAVRTGILTLLRSTINAEEPKFRNHTTSIEKTVKLVMGDLSVKVRKSTLLLIQTMCEKGYIEAREGWPLIDYIFSQFAMSNRNLENPIKSNSQEDENGEKSVQETSLEVLKSLDPLVIGMPQVLWPRILTYVVPKEYTGTLDYLFNIIRILIMAEEKKKRDIQESTALVVSTGAVKLPSPQQLLARLLVISILASLGQLCGAGAIGLLKIMPEIIHPKLAEMWKTRMPALLQPLEGSNASIVLWETMLLQLLKESLWKISDVAWTSQLSRDFSLQMGSYSNSSMEKKFLWKALGTTLASCQDKDFVSSQINEFLVTPSLLGDHRQGTTSILGFCAENHLDIVLNVLKTFQDKEKFFVNRCKGIFSGKKSLTKTDLILIYGAVALHAPKQQLLARLDQDIMGQILLLYGQCCQILGVSVINKDMDLQMSFTRSITEVGIAVQDAEDQKFQFTYKEMLIGSMLDLIKDEPLNTLASPVRWKVLIAIRYLSKLKPALSLNDHLNILEENIRRLLPLPPLEKLKSQGETDKDRERIEFLYERSMDALGKLLRSMIWDNTDAQNCEEMFNLLRMWLVSQKQWERERAFQVTSKVLTKDVEAPQNFRIGSLLGLLAPHSCDTLPTIRQAATSSTIGLLCAKGICQEVDRLQGLQEGLDSEDEQVQIKISSKIAKIVCKFIPSEEIQVFLEETLDGLETLDPLCTKACGIWMIAALKEHGALLEDQLLEILSTIYHHMPVLRQKEESFQFMLEAISQIASFHMDAVVNNLLQKPLPFDRDTKTLWKALAENPASSGKLMRALIKKLVARLEDDIAGTEAISVACAIYEVILTGAHITHLYPELFTLLLKLVSCSLGQKMPMSTLSQRRRVMQLGERQRFPDPCRLSTATLKCLQAQAMREGLAKESDEGDNLWTLLSNPDTHHIGVCALARSMAVWQHGVILDIMEHLLSSLTSSSENYRITGMAFFSELMKEPILWKHGNLRDVLIFMDQNARDSNAILRQMAIRGLGNTACGAPHKVRKYKQMMLECIIRGLYHLARTEVVCESLKALKKILELLTERDINFYFKEIVLQTRTFFEDEQDDVRLTAISLFEDLATLTGRRWKIFFAEEVKKSMISFLLHLWDPNPKIGAACRDVLVICIPFLGLQELYGLLDHLLERDLPRARDFYRQLCMKLSKKNQEILWILHTHSFTFFTSSWEMIRSAAVKLTDAIILHLTKRYVELLDREQLTMRLQALRQDPCISVQRAAEATLQTLLRRCKEISIPL
uniprot
proteins
function
FUNCTION: May play a role in the process of sperm capacitation (PubMed:27105888). {ECO:0000269|PubMed:27105888}.
uniprot
proteins
mass_dalton
180480
uniprot
proteins
post_translational_modification
PTM: Constitutively phosphorylated on serine and threonine residues in acrosomal region of the sperm head, midpiece and flagellar regions of noncapacitated spermatozoa. Phosphorylation on tyrosine residues increases upon sperm capacitation within the acrosomal and tail regions in a protein kinase A (PKA)-dependent signaling pathway. {ECO:0000269|PubMed:27105888}.
uniprot
proteins
pubmed
12783626
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
27105888
uniprot
proteins
sequence_length
1581
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27105888}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:27105888}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:27105888}. Note=Colocalizes with PRKACA and TCP11 on the acrosome and tail regions in round spermatids and spermatozoa regardless of the capacitation status of the sperm. {ECO:0000269|PubMed:27105888}.
uniprot
proteins