RRH
entrez
10692
canonical
uniprot
O14718
canonical
ensembl
ENSG00000180245
resolver
ensp
ENSP00000314992
resolver
enst
ENST00000317735
resolver
genesymbol
RRH
resolver
hgnc
HGNC:10450
resolver
uniprot
A1A4V2
resolver
uniprot
Q7RTS4
resolver
uniprot_entry
OPSX_HUMAN
resolver
uniprot_sec
A1A4V2
resolver
uniprot_sec
Q7RTS4
resolver
amino_acid_sequence
MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
uniprot
proteins
function
FUNCTION: Opsin-family protein localized to the apical microvilli of the retinal pigment epithelium (RPE), where it may participate in retinoid exchange between photoreceptors and RPE or light-dependent retinoid processing. Although it possesses the structural features of a GPCR, no evidence for canonical G protein activation in vivo has been reported. {ECO:0000250|UniProtKB:O35214}.
uniprot
proteins
mass_dalton
37423
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
protein_family
Opsin subfamily
uniprot
proteins
pubmed
12542842
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9275222
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:O35214}; Multi-pass membrane protein {ECO:0000255}. Note=Localized to the apical microvilli of RPE cells. {ECO:0000250|UniProtKB:O35214}.
uniprot
proteins
transmembrane_region
TRANSMEM 27..49; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 62..87; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 102..121; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 141..164; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 189..212; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 241..264; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 273..297; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins