PDGFRL
entrez
5157
canonical
uniprot
Q15198
canonical
ensembl
ENSG00000104213
resolver
ensp
ENSP00000251630
resolver
ensp
ENSP00000444211
resolver
enst
ENST00000251630
resolver
enst
ENST00000541323
resolver
genesymbol
PDGFRL
resolver
genesymbol_syn
PRLTS
resolver
hgnc
HGNC:8805
resolver
uniprot
A8K085
resolver
uniprot
Q6FH04
resolver
uniprot_entry
PGFRL_HUMAN
resolver
uniprot_sec
A8K085
resolver
uniprot_sec
Q6FH04
resolver
amino_acid_sequence
MKVWLLLGLLLVHEALEDVTGQHLPKNKRPKEPGENRIKPTNKKVKPKIPKMKDRDSANSAPKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIGWSYPAYLDTFKDSRLSVKQNERYGQLTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFFTEKGELFVPSPSYFDVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYDMKRGFVYLQPHSEHQGVVYCRAEAGGRSQISVKYQLLYVAVPSGPPSTTILASSNKVKSGDDISVLCTVLGEPDVEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVITVEDFETIDAGYYICTAQNLQGQTTVATTVEFS
uniprot
proteins
disease_involvement
DISEASE: Colorectal cancer (CRC) [MIM:114500]: A complex disease characterized by malignant lesions arising from the inner wall of the large intestine (the colon) and the rectum. Genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. Risk factors for cancer of the colon and rectum include colon polyps, long-standing ulcerative colitis, and genetic family history. {ECO:0000269|PubMed:7898930}. Note=The gene represented in this entry is involved in disease pathogenesis.; DISEASE: Note=A polymorphism in PDGFRL has been reported to be associated with susceptibility to Behcet disease (PubMed:22926996). Behcet disease is a complex multiple-system disorder characterized by recurrent oral ulcerations, recurrent genital ulcerations, typical skin lesions, and uveitis. Behcet disease also involves joints, blood vessels, musculoskeletal, neurological systems, and the gastrointestinal tract. {ECO:0000269|PubMed:22926996}.
uniprot
proteins
mass_dalton
41861
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19815557
uniprot
proteins
pubmed
22926996
uniprot
proteins
pubmed
7898930
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins