Ccny
entrez
67974
canonical
uniprot
Q8BGU5
canonical
ensembl
ENSMUSG00000024286
resolver
ensp
ENSMUSP00000050001
resolver
ensp
ENSMUSP00000282189
resolver
genesymbol
Ccny
resolver
genesymbol_syn
Cfp1
resolver
uniprot
Q8CI87
resolver
uniprot
Q9CYN5
resolver
uniprot_entry
CCNY_MOUSE
resolver
uniprot_sec
Q8CI87
resolver
uniprot_sec
Q9CYN5
resolver
amino_acid_sequence
MGNTTSCCVSSSPKLRRNAHSRLESYRPDTDLSREDTGCNLQHISDRENIDDLNMEFNPSDHPRASTIFLSKSQTDVREKRKSLFINHHPPGQTSRKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRLCEDKYKDLRKPMRKRSASADNLILPRWSPAIIS
uniprot
proteins
function
FUNCTION: Positive regulatory subunit of the cyclin-dependent kinase CDK14/PFTK1. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway (By similarity). Recruits CDK16 to the plasma membrane (By similarity). Positive regulatory subunit of the cyclin-dependent kinase CDK16. {ECO:0000250, ECO:0000269|PubMed:22184064}.
uniprot
proteins
mass_dalton
39395
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated; leading to its degradation. {ECO:0000250}.; PTM: Heavily phosphorylated. Phosphorylation at Ser-71 and Ser-73 by CDK14 is enhanced during the G2 and M cell cycle phases, and creates a phosphodegron triggering SCF-dependent ubiquitination. {ECO:0000250|UniProtKB:Q8ND76}.
uniprot
proteins
protein_family
Cyclin Y subfamily
uniprot
proteins
protein_family
Cyclin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22184064
uniprot
proteins
sequence_length
341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
uniprot
proteins