Dnajb11
entrez
67838
canonical
uniprot
Q99KV1
canonical
ensembl
ENSMUSG00000004460
resolver
ensp
ENSMUSP00000004574
resolver
ensp
ENSMUSP00000126828
resolver
ensp
ENSMUSP00000137542
resolver
enst
ENSMUST00000004574
resolver
enst
ENSMUST00000166487
resolver
enst
ENSMUST00000178320
resolver
genesymbol
Dnajb11
resolver
uniprot
A6X957
resolver
uniprot
Q543I7
resolver
uniprot
Q8BK79
resolver
uniprot
Q8VCY1
resolver
uniprot
Q8VHB1
resolver
uniprot_entry
DJB11_MOUSE
resolver
uniprot_sec
A6X957
resolver
uniprot_sec
Q543I7
resolver
uniprot_sec
Q8BK79
resolver
uniprot_sec
Q8VCY1
resolver
uniprot_sec
Q8VHB1
resolver
amino_acid_sequence
MAPQNLSTFCLLLLYLIGTVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHRIFERRGDDLYTNVTVSLVEALVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAKEGIKQLLKQGPVQKVYNGLQGY
uniprot
proteins
function
FUNCTION: As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1. {ECO:0000250|UniProtKB:Q9UBS4}.
uniprot
proteins
mass_dalton
40555
uniprot
proteins
post_translational_modification
PTM: Contains high-mannose Endo H-sensitive carbohydrates. {ECO:0000250}.; PTM: Cys-169, Cys-171, Cys-193 and Cys-196 form intramolecular disulfide bonds. The preferential partner for each Cys is not known (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
11584023
uniprot
proteins
pubmed
12475965
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15525676
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
358
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000269|PubMed:15525676}.
uniprot
proteins