Nol9
entrez
74035
canonical
uniprot
Q3TZX8
canonical
ensembl
ENSMUSG00000028948
resolver
ensp
ENSMUSP00000081133
resolver
ensp
ENSMUSP00000099486
resolver
ensp
ENSMUSP00000297454
resolver
genesymbol
Nol9
resolver
uniprot
A0PJC7
resolver
uniprot
B1AS65
resolver
uniprot
Q05A31
resolver
uniprot
Q8BQE1
resolver
uniprot
Q8C8L5
resolver
uniprot
Q8C9A8
resolver
uniprot
Q9D678
resolver
uniprot_entry
NOL9_MOUSE
resolver
uniprot_sec
A0PJC7
resolver
uniprot_sec
B1AS65
resolver
uniprot_sec
Q05A31
resolver
uniprot_sec
Q8BQE1
resolver
uniprot_sec
Q8C8L5
resolver
uniprot_sec
Q8C9A8
resolver
uniprot_sec
Q9D678
resolver
amino_acid_sequence
MAESEVLHRRAPSRSSWLRVRKARPHLLLSRRGRRRFGVLTRVELRRLRRRLLRAHALGGDWKQVAPAGAHVAVKCKLRARSRPAPRSPPTPSVPPAPCTASATCSLLNPRNHSTPQSRAGRPVRKVSPNVTQPVRDLGSGRVLMMLPPGEGFTFSGICRVTCVYGQLEVYGHIINQGQPPQDVFSVYTHSYLTINGVPYAEPEKSEKAIRREIRALLKPYTKLDDRNWVVRYFPPLGSIMILERMQSRFVDFLKTYKCSSYVLLQENAPVRVNSEFTTLKKIGIRRQKRKKAICLSESGLCALEELVSVSCDGCPVILLCGACDIGKSTFNRILINQLLNSIPGVDYLECDLGQTEFTPPGCVALLTITEPLLGPPYTHQRKPQRMVYYGKMNCYNDYENYIDIVKYVFRDYKREFPLIINTMGWVSDNGLRLLVDLIRVLSPNYVVQLYSDRCKFTPTLTSEYVELTDGLYTKSKIKRYRGFEIPEFGDNLEFTYEEKESSPLPVFTGHVLLSVHSEFLSSKNEKNRAKYNRIFRDLAVLGYLSQLMLPVPESLSPLHSLTPYQVPFSAVAIRVLHADVAPTHILYAVNASWVGLCRIVDDMKGYTRGPILLAQNPICDCLGFGICRGIDMDKRTYHILTPLPPEELKTVNCLLVGSISIPHCIFQNQPGPEGSVPYVTTDYNLNIPGATEKIGEREYGKAFPRHKLRQRRK
uniprot
proteins
ec_number
2.7.1.78
uniprot
proteins
function
FUNCTION: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of single-stranded and double-stranded RNA and DNA substrates (By similarity). Involved in rRNA processing and its kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. Required for the efficient pre-rRNA processing of internal transcribed spacer 2 (ITS2). Associates with LAS1L to form an ITS2 pre-rRNA endonuclease-kinase complex and is responsible for the transport of this complex into the nucleolus (By similarity). {ECO:0000250|UniProtKB:Q5SY16}.
uniprot
proteins
mass_dalton
80840
uniprot
proteins
protein_family
Clp1 family
uniprot
proteins
protein_family
NOL9/GRC3 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22872859
uniprot
proteins
sequence_length
714
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q5SY16}. Nucleus {ECO:0000269|PubMed:22872859}. Note=Colocalizes with pre-60S rRNP particles. {ECO:0000250|UniProtKB:Q5SY16}.
uniprot
proteins