DEPDC1
entrez
55635
canonical
uniprot
Q5TB30
canonical
ensembl
ENSG00000024526
resolver
ensp
ENSP00000360005
resolver
ensp
ENSP00000412292
resolver
genesymbol
DEPDC1
resolver
genesymbol_syn
DEPDC1A
resolver
hgnc
HGNC:22949
resolver
uniprot
A8QXE0
resolver
uniprot
A8QXE1
resolver
uniprot
Q05DU3
resolver
uniprot
Q5TB28
resolver
uniprot
Q9H9I3
resolver
uniprot
Q9NX21
resolver
uniprot
Q9NXZ0
resolver
uniprot_entry
DEP1A_HUMAN
resolver
uniprot_sec
A8QXE0
resolver
uniprot_sec
A8QXE1
resolver
uniprot_sec
Q05DU3
resolver
uniprot_sec
Q5TB28
resolver
uniprot_sec
Q9H9I3
resolver
uniprot_sec
Q9NX21
resolver
uniprot_sec
Q9NXZ0
resolver
amino_acid_sequence
MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYPELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRSSGIHKIQDDPQSSKFLHLNNLNSFKSTECLLLSLLHREKNKEESDSTERLQISNPGFQERCAKKMQLVNLRNRRVSANDIMGGSCHNLIGLSNMHDLSSNSKPRCCSLEGIVDVPGNSSKEASSVFHQSFPNIEGQNNKLFLESKPKQEFLLNLHSEENIQKPFSAGFKRTSTLTVQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEIIMKPNVGQGSTSVQTAMESELGESSATINKRLCKSTIELSENSLLPASSMLTGTQSLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR
uniprot
proteins
function
FUNCTION: May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. {ECO:0000269|PubMed:20587513}.
uniprot
proteins
mass_dalton
92960
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17452976
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20587513
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
811
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17452976, ECO:0000269|PubMed:20587513}. Note=Colocalizes with ZNF224 at the nucleus.
uniprot
proteins