Colec11
entrez
71693
canonical
uniprot
Q3SXB8
canonical
ensembl
ENSMUSG00000036655
resolver
ensp
ENSMUSP00000049285
resolver
ensp
ENSMUSP00000152876
resolver
ensp
ENSMUSP00000315810
resolver
enst
ENSMUST00000036136
resolver
enst
ENSMUST00000220836
resolver
genesymbol
Colec11
resolver
uniprot
A0A0R4J0M6
resolver
uniprot
A0A1Y7VKG6
resolver
uniprot
A0A7R7GPI6
resolver
uniprot
Q3SXB7
resolver
uniprot
Q9DC75
resolver
uniprot_entry
A0A0R4J0M6_MOUSE
resolver
uniprot_entry
A0A1Y7VKG6_MOUSE
resolver
uniprot_entry
A0A7R7GPI6_MOUSE
resolver
uniprot_entry
COL11_MOUSE
resolver
uniprot_sec
Q3SXB7
resolver
uniprot_sec
Q9DC75
resolver
amino_acid_sequence
MMMRDLALAGMLISLAFLSLLPSGCPQQTTEDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGTVGRHGKIGPIGAKGEKGDSGDIGPPGPSGEPGIPCECSQLRKAIGEMDNQVTQLTTELKFIKNAVAGLRETESKIYLLVKEEKRYADAQLSCQARGGTLSMPKDEAANGLMASYLAQAGLARVFIGINDLEKEGAFVYSDRSPMQTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHITMYFMCEFDKENL
uniprot
proteins
function
FUNCTION: Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis. {ECO:0000250|UniProtKB:Q9BWP8}.
uniprot
proteins
mass_dalton
28989
uniprot
proteins
protein_family
COLEC10/COLEC11 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21258343
uniprot
proteins
sequence_length
272
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q9BWP8}.
uniprot
proteins