GSTO1
entrez
9446
canonical
uniprot
P78417
canonical
ensembl
ENSG00000148834
resolver
ensp
ENSP00000358724
resolver
ensp
ENSP00000358727
resolver
ensp
ENSP00000441488
resolver
genesymbol
GSTO1
resolver
genesymbol
HEL-S-21
resolver
genesymbol_syn
GSTO1
resolver
genesymbol_syn
GSTTLP28
resolver
hgnc
HGNC:13312
resolver
uniprot
D3DRA3
resolver
uniprot
F5H7H0
resolver
uniprot
Q5TA03
resolver
uniprot
Q7Z3T2
resolver
uniprot
V9HWG9
resolver
uniprot_entry
GSTO1_HUMAN
resolver
uniprot_entry
V9HWG9_HUMAN
resolver
uniprot_sec
D3DRA3
resolver
uniprot_sec
F5H7H0
resolver
uniprot_sec
Q5TA03
resolver
uniprot_sec
Q7Z3T2
resolver
activity_regulation
ACTIVITY REGULATION: Monomethylarsonic acid reductase activity is competitively inhibited by 1-chloro 2,4-dinitrobenzene (CDNB) and by deoxycholate.
uniprot
proteins
amino_acid_sequence
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
uniprot
proteins
ec_number
1.20.4.2
uniprot
proteins
ec_number
1.8.5.1
uniprot
proteins
ec_number
2.5.1.18
uniprot
proteins
function
FUNCTION: Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Also has glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. {ECO:0000269|PubMed:10783391, ECO:0000269|PubMed:11511179, ECO:0000269|PubMed:17226937, ECO:0000269|PubMed:18028863, ECO:0000269|PubMed:21106529}.
uniprot
proteins
mass_dalton
27566
uniprot
proteins
mutagenesis
MUTAGEN 32; /note="C->A: Loss of activity."; /evidence="ECO:0000269|PubMed:17226937
uniprot
proteins
protein_family
GST superfamily
uniprot
proteins
protein_family
Omega family
uniprot
proteins
pubmed
10783391
uniprot
proteins
pubmed
11271497
uniprot
proteins
pubmed
11511179
uniprot
proteins
pubmed
12618591
uniprot
proteins
pubmed
12928150
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17226937
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18028863
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21106529
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
241
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:11511179}.
uniprot
proteins