Neto2
entrez
307757
canonical
uniprot
C6K2K4
canonical
ensembl
ENSRNOG00000016245
resolver
ensembl
ENSRNOG00055020093
resolver
ensembl
ENSRNOG00060015203
resolver
ensembl
ENSRNOG00065010632
resolver
ensp
ENSRNOP00000021739
resolver
ensp
ENSRNOP00055027806
resolver
ensp
ENSRNOP00060020900
resolver
ensp
ENSRNOP00065013162
resolver
enst
ENSRNOT00000021739
resolver
enst
ENSRNOT00055034329
resolver
enst
ENSRNOT00060026106
resolver
enst
ENSRNOT00065017214
resolver
genesymbol
Neto2
resolver
genesymbol_syn
Btcl2
resolver
uniprot_entry
NETO2_RAT
resolver
amino_acid_sequence
MALEQLCAVLKVLLITVLVVEGIAVAQKTQDGQNIGIKHVPATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDERYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGMKSPALIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSAIENLKAKFCSTVANDVMLKTGVGVIRMWADEGSRLSRFRMLFTSFVEPPCTSSTFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGLFEQITKTHGTIIGVTSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLREKEISADLADLSEELDNYQKLRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRNDFAQPQPMKTFNSTFKKSSYTFKQTHDCPEQALEDRVMEEIPCEIYVRGRDDSAQASISIDF
uniprot
proteins
function
FUNCTION: Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission. {ECO:0000269|PubMed:19217376}.
uniprot
proteins
mass_dalton
59342
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:19217376}.
uniprot
proteins
pubmed
19217376
uniprot
proteins
sequence_length
525
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 348..368; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins