P97366
uniprot
P97366
canonical
amino_acid_sequence
MVTTKMTAAFRNPNRRQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPTQSPSSPSKLSPDDLELLAKLEEQNRLIETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWDDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCNAQSMTIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRELVTVRAVLSSLDCCCMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEYLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGGPEKLIQSAYQVKYNSKKMKKLEKEYTTIKTKEMEEQGEIKRLRTENRLLKQRIETLEKHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPDENNIARLQEELIAVKLREAEAIMGLKELRQQVRTLEEHWQRHLARTSGRWKDPPKKNAVNELQDELMSIRLREAETQAEIREMKQRMMEMETQNQINSNQLRRAEQEVNSLQEKVCSLSVKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAELQQHIAELEIQKEEGKLQGQLNRSDSNQYIRELKDQIAELTHELRCLKGQRDFSSRPPFDGIHIVSHLIGDDELFHSSDEDFIDSSLQESAIGFPLHRKSGPMSLNPALADGSESEAEDGMLGPQESDPEAPQKQPPQRESYSTTV
uniprot
proteins
function
FUNCTION: Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
92943
uniprot
proteins
post_translational_modification
PTM: Probably phosphorylated by PLK1; may be required for degradation during mitosis. {ECO:0000250}.; PTM: Ubiquitinated. Degradation during prophase is ubiquitin-dependent (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9070650
uniprot
proteins
sequence_length
809
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis. {ECO:0000250}.
uniprot
proteins