Syde1
entrez
362842
canonical
uniprot
D3ZZN9
canonical
ensembl
ENSRNOG00000007307
resolver
ensp
ENSRNOP00000009606
resolver
enst
ENSRNOT00000009606
resolver
genesymbol
Syde1
resolver
uniprot_entry
SYDE1_RAT
resolver
amino_acid_sequence
MAEPLLRKTFSRLRGREKLPRKKSDAKDRGRPAQRSEPKPPEPEPRVLEGSQAGAEVPLSPETPRSPARGAYLQSLEPSSRRWVLGGAKPPEEISLGPRTPSSGEPAGEIWYNPIPEEDPRPPAPEPVGSQLASSEPEGPILQGAAPTSPPTKTSRTKSPGPARRLSMKMKKLPELRRRLSLRSTRTSRERERTAPAGSVISRYHLDSSVATPGQASVAGGTRSPRGGYLSDGDSPERPGGPPSPTAFRPYEVGPSARAPPAALWGRLSLHLYGLGGLRPTPGATPRDLCCLLQVDGVARARTGPLRSGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTIFRGCQAQQLAVRLEPQGLLYAKLTLSEQQEAPATVEPRVFGLPLQLLVEREQSPGQVPLIIRKCVGQIECRGLRVVGLYRLCGSAAVKKELRDAFEQDSAAVCLSEDVYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMAQGHPSRASLGPEGTRGLLSCLPDVERATLTLLLDHLRLVSSFHTHNRMTPQNLAVCFGPVLLPARQTPSRTRLRGSGPGVSSAVDFKRHIEVLHYLLQSWPDTRRPSETPDVAPYLRPKRQPPLHLPLDGPEVVTRPRGRGGPESPPSNRYAGDWSVCGGDLLPRGRDFLSGPDYDHVTGSDSEEDEDESGEPRGTTDFEDEFDAPFNPHLNLKDFDALILDLERELSKQINVCL
uniprot
proteins
function
FUNCTION: GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1. {ECO:0000250|UniProtKB:Q6ZW31}.
uniprot
proteins
mass_dalton
80378
uniprot
proteins
post_translational_modification
PTM: Palmitoylated (PubMed:23687301). Probably palmitoylated by ZDHHC3 and ZDHHC7 (PubMed:23687301). {ECO:0000269|PubMed:23687301}.
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
23687301
uniprot
proteins
sequence_length
735
uniprot
proteins