Nsun5
entrez
100609
canonical
uniprot
Q8K4F6
canonical
ensembl
ENSMUSG00000000916
resolver
ensp
ENSMUSP00000000940
resolver
ensp
ENSMUSP00000257829
resolver
ensp
ENSMUSP00000257853
resolver
ensp
ENSMUSP00000345947
resolver
enst
ENSMUST00000000940
resolver
genesymbol
Nsun5
resolver
genesymbol_syn
Wbscr20a
resolver
uniprot
Q3U0Q8
resolver
uniprot
Q80WG3
resolver
uniprot
Q8C568
resolver
uniprot_entry
NSUN5_MOUSE
resolver
uniprot_sec
Q3U0Q8
resolver
uniprot_sec
Q80WG3
resolver
uniprot_sec
Q8C568
resolver
amino_acid_sequence
MGLYAAAAAVLAGVESRQGSLKGLVYSSNFQNLKQLYALVCETQRYSAVLDAVIASAGLLRAEKKLRPHLAKVLVYELLLGKGFRGGGGRWKALLGRHQARLKAELARLKVHRGVSRNEDLLQESSRPGQAYQVPRFVRVNTLKTRPEDAIDYFKRQGFSYQGRASSLEDLRALKGQHFLLDPLLPELLVFPAQTDLHEHPLYRAGHLILQDKASCLPAMLLSPPPGSHVIDACAAPGNKTSYIAALLKNQGKIFAFDQDAKRLAAMATLVARAGVSCCELAEKDFLTVSPSDQRYSQVQYILLDPSCSGSGMLSRQLEEHGEGTPSKERLQALAGFQQRALCHALRFPSLQRLVYSTCSLCQEENEDVVQEALQHNSGTFRLAPVLPTWPHRGLSTFPGSEHCLRASPETTLTGGFFIAVFERAEVVPTPAPQTDAMDPEPLSQVPKRKRRRKAAVGASMQPST
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3438 (m5C3438) in 28S rRNA (PubMed:31722427). m5C3782 promotes protein translation without affecting ribosome biogenesis and fidelity (By similarity). Required for corpus callosum and cerebral cortex development (PubMed:31174389, PubMed:31462248). {ECO:0000250|UniProtKB:Q96P11, ECO:0000269|PubMed:31174389, ECO:0000269|PubMed:31462248, ECO:0000269|PubMed:31722427}.
uniprot
proteins
mass_dalton
51030
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
RsmB/NOP family
uniprot
proteins
pubmed
12073013
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
30485550
uniprot
proteins
pubmed
31174389
uniprot
proteins
pubmed
31462248
uniprot
proteins
pubmed
31722427
uniprot
proteins
sequence_length
465
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q96P11}.
uniprot
proteins