NUDT6
entrez
11162
canonical
uniprot
P53370
canonical
ensembl
ENSG00000170917
resolver
ensp
ENSP00000306070
resolver
ensp
ENSP00000344011
resolver
genesymbol
NUDT6
resolver
genesymbol_syn
FGF2AS
resolver
hgnc
HGNC:8053
resolver
uniprot
A8K756
resolver
uniprot
B4DG76
resolver
uniprot
O95097
resolver
uniprot
Q9UQD9
resolver
uniprot_entry
B4DG76_HUMAN
resolver
uniprot_entry
NUDT6_HUMAN
resolver
uniprot_sec
A8K756
resolver
uniprot_sec
O95097
resolver
uniprot_sec
Q9UQD9
resolver
activity_regulation
ACTIVITY REGULATION: Mn(2+) has a strong inhibitory effet on ADP-ribose diphosphatase activity. {ECO:0000269|PubMed:37343711}.
uniprot
proteins
amino_acid_sequence
MRQPLSWGRWRAMLARTYGPGPSAGYRWASGAQGYVRNPPVGACDLQGELDRFGGISVRLARLDALDRLDAAAFQKGLQAAVQQWRSEGRTAVWLHIPILQSRFIAPAASLGFCFHHAESDSSTLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEEDIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQEECLRCEWMDLNDLAKTENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKLYHKELPENYKTMKGID
uniprot
proteins
ec_number
3.6.1.18
uniprot
proteins
ec_number
3.6.1.22
uniprot
proteins
function
FUNCTION: Mediates the hydrolysis of some nucleoside diphosphate derivatives, such as NADH and FAD (in vitro) (PubMed:37343711). May contribute to the regulation of cell proliferation (PubMed:11266510). {ECO:0000269|PubMed:11266510, ECO:0000269|PubMed:37343711}.
uniprot
proteins
mass_dalton
35679
uniprot
proteins
protein_family
Nudix hydrolase family
uniprot
proteins
pubmed
10022609
uniprot
proteins
pubmed
11266510
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17569023
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
37343711
uniprot
proteins
pubmed
7984147
uniprot
proteins
sequence_length
316
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:17569023, ECO:0000269|PubMed:37343711}. Note=Localizes exclusively to the mitochondria. {ECO:0000269|PubMed:37343711}.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus {ECO:0000269|PubMed:17569023}. Cytoplasm {ECO:0000269|PubMed:17569023}.
uniprot
proteins