CPNE3
entrez
8895
canonical
uniprot
O75131
canonical
ensembl
ENSG00000085719
resolver
ensp
ENSP00000477590
resolver
ensp
ENSP00000547783
resolver
ensp
ENSP00000547784
resolver
ensp
ENSP00000547786
resolver
ensp
ENSP00000547787
resolver
ensp
ENSP00000547789
resolver
ensp
ENSP00000608009
resolver
ensp
ENSP00000640568
resolver
ensp
ENSP00000640569
resolver
ensp
ENSP00000640570
resolver
ensp
ENSP00000640571
resolver
ensp
ENSP00000640572
resolver
ensp
ENSP00000640573
resolver
enst
ENST00000517490
resolver
enst
ENST00000877724
resolver
enst
ENST00000877725
resolver
enst
ENST00000877727
resolver
enst
ENST00000877728
resolver
enst
ENST00000877730
resolver
enst
ENST00000937950
resolver
enst
ENST00000970509
resolver
enst
ENST00000970510
resolver
enst
ENST00000970511
resolver
enst
ENST00000970512
resolver
enst
ENST00000970513
resolver
enst
ENST00000970514
resolver
genesymbol
CPNE3
resolver
genesymbol_syn
CPN3
resolver
genesymbol_syn
KIAA0636
resolver
hgnc
HGNC:2316
resolver
uniprot
A8KA47
resolver
uniprot
Q8IYA1
resolver
uniprot_entry
CPNE3_HUMAN
resolver
uniprot_sec
A8KA47
resolver
uniprot_sec
Q8IYA1
resolver
amino_acid_sequence
MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ
uniprot
proteins
function
FUNCTION: Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation (PubMed:20010870). {ECO:0000269|PubMed:20010870}.
uniprot
proteins
mass_dalton
60131
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on serine and threonine residues (PubMed:11041869). {ECO:0000269|PubMed:11041869}.
uniprot
proteins
protein_family
Copine family
uniprot
proteins
pubmed
11041869
uniprot
proteins
pubmed
12949241
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20010870
uniprot
proteins
pubmed
21087455
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9734811
uniprot
proteins
sequence_length
537
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20010870, ECO:0000269|PubMed:21087455}. Cytoplasm {ECO:0000269|PubMed:12949241, ECO:0000269|PubMed:20010870, ECO:0000269|PubMed:21087455}. Cell membrane {ECO:0000269|PubMed:20010870, ECO:0000269|PubMed:21087455}. Cell junction {ECO:0000269|PubMed:20010870}. Cell junction, focal adhesion {ECO:0000269|PubMed:20010870}. Note=Associates to the membrane in a calcium-dependent manner (PubMed:20010870). Translocates to the cell membrane and the nucleus in a calcium- or growth factor heregulin-dependent manner (PubMed:20010870, PubMed:21087455). Colocalizes with the tyrosine phosphorylated ERBB2 form at cell membrane and focal adhesions in a calcium- or growth factor heregulin-dependent manner (PubMed:20010870). {ECO:0000269|PubMed:20010870, ECO:0000269|PubMed:21087455}.
uniprot
proteins