BLMH
entrez
642
canonical
uniprot
Q13867
canonical
ensembl
ENSG00000108578
resolver
ensp
ENSP00000261714
resolver
enst
ENST00000261714
resolver
genesymbol
BLMH
resolver
hgnc
HGNC:1059
resolver
uniprot
B2R796
resolver
uniprot
Q53F86
resolver
uniprot
Q9UER9
resolver
uniprot_entry
BLMH_HUMAN
resolver
uniprot_sec
B2R796
resolver
uniprot_sec
Q53F86
resolver
uniprot_sec
Q9UER9
resolver
amino_acid_sequence
MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE
uniprot
proteins
ec_number
3.4.22.40
uniprot
proteins
function
FUNCTION: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity. {ECO:0000250}.
uniprot
proteins
mass_dalton
52562
uniprot
proteins
protein_family
Peptidase C1 family
uniprot
proteins
pubmed
10404591
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
31875550
uniprot
proteins
pubmed
8620487
uniprot
proteins
pubmed
8639621
uniprot
proteins
sequence_length
455
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:31875550}. Cytoplasmic granule {ECO:0000269|PubMed:31875550}. Note=Co-localizes with NUDT12 in the cytoplasmic granules. {ECO:0000269|PubMed:31875550}.
uniprot
proteins