APCS
entrez
325
canonical
uniprot
P02743
canonical
ensembl
ENSG00000132703
resolver
ensp
ENSP00000255040
resolver
enst
ENST00000255040
resolver
genesymbol
APCS
resolver
genesymbol
HEL-S-92n
resolver
genesymbol_syn
APCS
resolver
genesymbol_syn
PTX2
resolver
hgnc
HGNC:584
resolver
uniprot
V9HWP0
resolver
uniprot_entry
SAMP_HUMAN
resolver
uniprot_entry
V9HWP0_HUMAN
resolver
amino_acid_sequence
MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYSDLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESSSGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
uniprot
proteins
disease_involvement
DISEASE: Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
uniprot
proteins
function
FUNCTION: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
uniprot
proteins
mass_dalton
25387
uniprot
proteins
post_translational_modification
PTM: N-glycosylated with a complex biantennary oligosaccharide chain with a sialic acid at the end (disialo-SAP). Monosialo-SAP as well as asioalo-SAP are also detected (PubMed:15174148). {ECO:0000269|PubMed:15174148, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218}.
uniprot
proteins
protein_family
Pentraxin family
uniprot
proteins
pubmed
15174148
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2987268
uniprot
proteins
pubmed
3029048
uniprot
proteins
pubmed
4055725
uniprot
proteins
pubmed
8114934
uniprot
proteins
pubmed
81686
uniprot
proteins
pubmed
8202534
uniprot
proteins
pubmed
9217261
uniprot
proteins
sequence_length
223
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins