Eras
entrez
353283
canonical
uniprot
Q7TN89
canonical
ensembl
ENSMUSG00000031160
resolver
ensp
ENSMUSP00000033500
resolver
enst
ENSMUST00000033500
resolver
genesymbol
Eras
resolver
uniprot
Q0VEC9
resolver
uniprot_entry
Q0VEC9_MOUSE
resolver
uniprot_entry
RASE_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).
uniprot
proteins
amino_acid_sequence
MALPTKSSILDLSSGTPCTRSPEESHEAWAQCKDAGRQLPEYKAVVVGASGVGKSALTIQMTHQCFVKDHDPTIQDSYWKEVARDNGGYILNVLDTSGQDIHRALRDQCLASGDGVLGVFALDDPSSLDQLQQIWSTWTPHHKQPLVLVGNKCDLVTTAGDAHAAAALLAHKLGAPLVKTSAKTRQGVEEAFALLVHEIQRAQEAVAESSKKTRHQKAVCSCGCSVA
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. {ECO:0000269|PubMed:12774123}.
uniprot
proteins
mass_dalton
24321
uniprot
proteins
protein_family
Ras family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
12774123
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
uniprot
proteins