STS
entrez
412
canonical
uniprot
P08842
canonical
ensembl
ENSG00000101846
resolver
ensp
ENSP00000217961
resolver
ensp
ENSP00000499472
resolver
ensp
ENSP00000501534
resolver
ensp
ENSP00000540857
resolver
ensp
ENSP00000540858
resolver
ensp
ENSP00000540859
resolver
ensp
ENSP00000604658
resolver
ensp
ENSP00000632919
resolver
enst
ENST00000217961
resolver
enst
ENST00000666110
resolver
enst
ENST00000674429
resolver
enst
ENST00000870798
resolver
enst
ENST00000870799
resolver
enst
ENST00000870800
resolver
enst
ENST00000934599
resolver
enst
ENST00000962860
resolver
genesymbol
STS
resolver
genesymbol_syn
ARSC1
resolver
hgnc
HGNC:11425
resolver
uniprot
A0A590UJL0
resolver
uniprot
A0A6I8PRU4
resolver
uniprot
A6PYA4
resolver
uniprot
B2RA47
resolver
uniprot
Q0W975
resolver
uniprot_entry
A0A590UJL0_HUMAN
resolver
uniprot_entry
A6PYA4_HUMAN
resolver
uniprot_entry
Q0W975_HUMAN
resolver
uniprot_entry
STS_HUMAN
resolver
uniprot_sec
A0A6I8PRU4
resolver
uniprot_sec
B2RA47
resolver
amino_acid_sequence
MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNGCFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQTLPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR
uniprot
proteins
disease_involvement
DISEASE: Ichthyosis, X-linked (IXL) [MIM:308100]: A keratinization disorder manifesting with mild erythroderma and generalized exfoliation of the skin within a few weeks after birth. Affected boys later develop large, polygonal, dark brown scales, especially on the neck, extremities, trunk, and buttocks. {ECO:0000269|PubMed:10679952, ECO:0000269|PubMed:10844566, ECO:0000269|PubMed:1539590, ECO:0000269|PubMed:9252398}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
3.1.6.2
uniprot
proteins
function
FUNCTION: Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid. {ECO:0000269|PubMed:10844566, ECO:0000269|PubMed:23466819, ECO:0000269|PubMed:9252398}.
uniprot
proteins
mass_dalton
65492
uniprot
proteins
post_translational_modification
PTM: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. {ECO:0000269|PubMed:12657638}.
uniprot
proteins
protein_family
Sulfatase family
uniprot
proteins
pubmed
10679952
uniprot
proteins
pubmed
10844566
uniprot
proteins
pubmed
12657638
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
1539590
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23466819
uniprot
proteins
pubmed
2668275
uniprot
proteins
pubmed
2765556
uniprot
proteins
pubmed
3032454
uniprot
proteins
pubmed
3203382
uniprot
proteins
pubmed
9252398
uniprot
proteins
sequence_length
583
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, microneme membrane {ECO:0000269|PubMed:2668275}; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000269|PubMed:2668275}; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 185..208; /note="Helical"; /evidence="ECO:0000269|PubMed:2668275"; TRANSMEM 213..234; /note="Helical"; /evidence="ECO:0000269|PubMed:2668275
uniprot
proteins