Bpnt2
entrez
312952
canonical
uniprot
D4AD37
canonical
ensembl
ENSRNOG00000046647
resolver
ensembl
ENSRNOG00055020100
resolver
ensembl
ENSRNOG00060010407
resolver
ensembl
ENSRNOG00065015569
resolver
ensp
ENSRNOP00000067120
resolver
ensp
ENSRNOP00055027822
resolver
ensp
ENSRNOP00060013712
resolver
ensp
ENSRNOP00065020362
resolver
enst
ENSRNOT00000072803
resolver
enst
ENSRNOT00055034350
resolver
enst
ENSRNOT00060017641
resolver
enst
ENSRNOT00065025876
resolver
genesymbol
Bpnt2
resolver
genesymbol_syn
Impa3
resolver
genesymbol_syn
Impad1
resolver
uniprot_entry
IMPA3_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Strongly inhibited by lithium. {ECO:0000250|UniProtKB:Q80V26}.
uniprot
proteins
amino_acid_sequence
MAPMGIRLSPLGVAVFFLLGLGVLYHLYSGFLAGRFSLFGLGGEPAGGAAEVAVDGGTVDLREMLAVAVLAAERGGDEVRRVRESNVLHEKSKGKTREGAEDKMTSGDVLSNRKMFYLLKTAFPNVQINTEEHVDASDKEVIVWNRKIPEDILKEIAAPKEVPAESVTVWIDPLDATQEYTEDLRKYVTTMVCVAVNGKPVLGVIHKPFSEYTAWAMVDSGSNVKARSSYNEKTPKIIVSRSHAGMVKQVALQTFGNQTLIIPAGGAGYKVLALLDVPDMTQEKADLYIHVTYIKKWDICAGNAILKALGGHMTTLSGEEISYTGSDGIEGGLLASIRMNHQALVRKLPDLEKSGH
uniprot
proteins
ec_number
3.1.3.7
uniprot
proteins
function
FUNCTION: Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4. {ECO:0000250|UniProtKB:Q80V26}.
uniprot
proteins
mass_dalton
38569
uniprot
proteins
pathway_participation
PATHWAY: Sulfur metabolism. {ECO:0000250|UniProtKB:Q80V26}.
uniprot
proteins
post_translational_modification
PTM: Contains N-linked glycan resistant to endoglycosydase H. {ECO:0000250|UniProtKB:Q9NX62}.
uniprot
proteins
protein_family
Inositol monophosphatase superfamily
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q80V26, ECO:0000250|UniProtKB:Q9NX62}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q80V26, ECO:0000250|UniProtKB:Q9NX62}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9NX62}. Note=The catalytic core is predicted to reside within the Golgi lumen. {ECO:0000250|UniProtKB:Q9NX62}.
uniprot
proteins
transmembrane_region
TRANSMEM 13..33; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins