Gpr19
entrez
14760
canonical
uniprot
Q61121
canonical
ensembl
ENSMUSG00000032641
resolver
ensp
ENSMUSP00000047630
resolver
ensp
ENSMUSP00000107563
resolver
ensp
ENSMUSP00000112214
resolver
ensp
ENSMUSP00000127876
resolver
ensp
ENSMUSP00000297608
resolver
ensp
ENSMUSP00000297613
resolver
ensp
ENSMUSP00000297614
resolver
ensp
ENSMUSP00000343019
resolver
genesymbol
Gpr19
resolver
uniprot
Q810I4
resolver
uniprot
Q8VDJ9
resolver
uniprot_entry
GPR19_MOUSE
resolver
uniprot_sec
Q810I4
resolver
uniprot_sec
Q8VDJ9
resolver
amino_acid_sequence
MVFAHRMDNDQPPVVTATLLVPLQNSSCAEAAEALLPHGLMGLHEEHSWMSNRTELQYELNPGEVATASIFFGALWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVVLQFTTGRWTLGSAMCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWILDAAFVTPVFFFYGSNWDSHCNYFLPPSWEGTAYTVIHFLVGFVIPSILIILFYQKVIKYIWRIGTDGRTLRRTMNIVPRTKVKTVKMFLLLNLVFLFSWLPFHVAQLWHPHEQDYKKSSLVFTAVTWVSFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKRNYVGISEIPPVSRTITKDSIYDSFDREAREKKLAWPINSNPPNTFV
uniprot
proteins
function
FUNCTION: G protein-coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism (PubMed:34789778, PubMed:37061564). Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain (PubMed:34789778). May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence (By similarity). Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity (By similarity). {ECO:0000250|UniProtKB:P70585, ECO:0000250|UniProtKB:Q15760, ECO:0000269|PubMed:34789778, ECO:0000269|PubMed:37061564}.
uniprot
proteins
mass_dalton
47533
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
34789778
uniprot
proteins
pubmed
37061564
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 70..90; /note="Helical; Name=1"; TRANSMEM 103..123; /note="Helical; Name=2"; TRANSMEM 153..173; /note="Helical; Name=3"; TRANSMEM 183..203; /note="Helical; Name=4"; TRANSMEM 222..242; /note="Helical; Name=5"; TRANSMEM 278..298; /note="Helical; Name=6"; TRANSMEM 310..332; /note="Helical; Name=7
uniprot
proteins