Ric3
entrez
320360
canonical
uniprot
Q8BPM6
canonical
ensembl
ENSMUSG00000048330
resolver
ensp
ENSMUSP00000056990
resolver
ensp
ENSMUSP00000112788
resolver
ensp
ENSMUSP00000337745
resolver
enst
ENSMUST00000120876
resolver
genesymbol
Ric3
resolver
uniprot
D3YTZ9
resolver
uniprot
Q6PCM7
resolver
uniprot
Q8C4G2
resolver
uniprot_entry
D3YTZ9_MOUSE
resolver
uniprot_entry
RIC3_MOUSE
resolver
uniprot_sec
Q6PCM7
resolver
uniprot_sec
Q8C4G2
resolver
amino_acid_sequence
MAYSTVQRVALASGLVLAVSLLLPKAFLSRGKRPEPPPGPEGKLDRFPPMMHHHSAPSDGQTPGARFQRSHLAEAFAKAKGAGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTAEDRNCSTAPPGNAHRKITNFELVQLQEKLKETEEAMEKLINRVGPNGESRAQAVTSDQEKRLLHQLREITRVMKEGKFIDTSPEKEAEEAPYMEDWEGYPEETYPIYDLSDGIKRRQETILVDYPDLKEPSAEEIAEQMGEIEEEGSERLSWDHLPTDPGAQKDNSVAPCDPKPESCSCCVHEEEDPAVLAENAGFSADGYSEQEEATKENLPQDFTNEGLGVSTDNAHVGGMLRKRNPQGFE
uniprot
proteins
function
FUNCTION: Molecular chaperone which promotes the proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) nicotinic acetylcholine receptor (PubMed:19812337, PubMed:32204458). Promotes the proper subunit assembly and cell surface expression of alpha-8 (CHRNA8) nicotinic acetylcholine receptor (By similarity). May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4 (By similarity). {ECO:0000250|UniProtKB:Q7Z5B4, ECO:0000269|PubMed:19812337, ECO:0000269|PubMed:32204458}.
uniprot
proteins
mass_dalton
40283
uniprot
proteins
protein_family
Ric-3 family
uniprot
proteins
pubmed
12821669
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19812337
uniprot
proteins
pubmed
32204458
uniprot
proteins
sequence_length
367
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19812337}; Single-pass membrane protein {ECO:0000269|PubMed:19812337}.
uniprot
proteins
transmembrane_region
TRANSMEM 96..116; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins