Pdgfb
entrez
18591
canonical
uniprot
P31240
canonical
ensembl
ENSMUSG00000000489
resolver
ensp
ENSMUSP00000000500
resolver
ensp
ENSMUSP00000155133
resolver
enst
ENSMUST00000000500
resolver
genesymbol
Pdgfb
resolver
genesymbol_syn
Sis
resolver
uniprot
A0A0R4IZW4
resolver
uniprot
Q6P3C4
resolver
uniprot_entry
A0A0R4IZW4_MOUSE
resolver
uniprot_entry
PDGFB_MOUSE
resolver
uniprot_sec
Q6P3C4
resolver
amino_acid_sequence
MNRCWALFLPLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHRDSVDEDGAELDLNMTRAHSGVELESSSRGRRSLGSLAAAEPAVIAECKTRTEVFQISRNLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRASQVQMRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETIVTPRPVTRSPGTSREQRAKTPQARVTIRTVRIRRPPKGKHRKFKHTHDKAALKETLGA
uniprot
proteins
function
FUNCTION: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. {ECO:0000269|PubMed:10734101, ECO:0000269|PubMed:14561699, ECO:0000269|PubMed:19030102, ECO:0000269|PubMed:7958863}.
uniprot
proteins
mass_dalton
27382
uniprot
proteins
protein_family
PDGF/VEGF growth factor family
uniprot
proteins
pubmed
10734101
uniprot
proteins
pubmed
11264163
uniprot
proteins
pubmed
14514732
uniprot
proteins
pubmed
14561699
uniprot
proteins
pubmed
15207812
uniprot
proteins
pubmed
15207813
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19030102
uniprot
proteins
pubmed
2045107
uniprot
proteins
pubmed
7958863
uniprot
proteins
pubmed
9211853
uniprot
proteins
sequence_length
241
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted. Note=Released by platelets upon wounding. {ECO:0000250}.
uniprot
proteins