Fbln5
entrez
23876
canonical
uniprot
Q9WVH9
canonical
ensembl
ENSMUSG00000021186
resolver
ensp
ENSMUSP00000021603
resolver
ensp
ENSMUSP00000152680
resolver
ensp
ENSMUSP00000178581
resolver
enst
ENSMUST00000021603
resolver
enst
ENSMUST00000222587
resolver
genesymbol
Fbln5
resolver
genesymbol_syn
Dance
resolver
uniprot
A0A1Y7VJW9
resolver
uniprot
Q541Z7
resolver
uniprot_entry
A0A1Y7VJW9_MOUSE
resolver
uniprot_entry
FBLN5_MOUSE
resolver
uniprot_sec
Q541Z7
resolver
amino_acid_sequence
MPGLKRILTVTILALWLPHPGNAQQQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSTSYSGPYPAAAPPVPASNYPTISRPLVCRFGYQMDEGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNDDGRSCQDVNECETENPCVQTCVNTYGSFICRCDPGYELEEDGIHCSDMDECSFSEFLCQHECVNQPGSYFCSCPPGYVLLDDNRSCQDINECEHRNHTCTSLQTCYNLQGGFKCIDPISCEEPYLLIGENRCMCPAEHTSCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPRDIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF
uniprot
proteins
function
FUNCTION: Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (By similarity). Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:11805835). May act as an adapter that mediates the interaction between FBN1 and ELN (By similarity). {ECO:0000250|UniProtKB:Q9UBX5, ECO:0000269|PubMed:11805835}.
uniprot
proteins
mass_dalton
50193
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q9UBX5}.
uniprot
proteins
protein_family
Fibulin family
uniprot
proteins
pubmed
10428823
uniprot
proteins
pubmed
11805835
uniprot
proteins
pubmed
14745449
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
448
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q9UBX5}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:14745449}. Note=co-localizes with ELN in elastic fibers. {ECO:0000250|UniProtKB:Q9UBX5}.
uniprot
proteins