Ptgr2
entrez
77219
canonical
uniprot
Q8VDQ1
canonical
ensembl
ENSMUSG00000072946
resolver
ensp
ENSMUSP00000115704
resolver
ensp
ENSMUSP00000119981
resolver
ensp
ENSMUSP00000169042
resolver
genesymbol
Ptgr2
resolver
genesymbol_syn
Zadh1
resolver
uniprot
Q3TG36
resolver
uniprot
Q3ULY3
resolver
uniprot
Q8BZA2
resolver
uniprot
Q9D1W8
resolver
uniprot_entry
PTGR2_MOUSE
resolver
uniprot_sec
Q3TG36
resolver
uniprot_sec
Q3ULY3
resolver
uniprot_sec
Q8BZA2
resolver
uniprot_sec
Q9D1W8
resolver
amino_acid_sequence
MIIQRVVLNSRPGKNGNPVAENFRVEEFSLPDALNEGQVQVRTLYLSVDPYMRCKMNEDTGTDYLAPWQLAQVADGGGIGVVEESKHQKLTKGDFVTSFYWPWQTKAILDGNGLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHLLGCSRVVGICGTQEKCLFLTSELGFDAAVNYKTGNVAEQLREACPGGVDVYFDNVGGDISNAVISQMNENSHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVLNYKDKFEPGILQLSQWFKEGKLKVKETMAKGLENMGVAFQSMMTGGNVGKQIVCISEDSSL
uniprot
proteins
ec_number
1.3.1.48
uniprot
proteins
function
FUNCTION: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. {ECO:0000269|PubMed:17449869}.
uniprot
proteins
mass_dalton
38015
uniprot
proteins
mutagenesis
MUTAGEN 259; /note="Y->F: Significant reduction in catalytic efficiency."; /evidence="ECO:0000269|PubMed:17449869
uniprot
proteins
protein_family
NADP-dependent oxidoreductase L4BD family
uniprot
proteins
pubmed
15229897
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17449869
uniprot
proteins
pubmed
19000823
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
351
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins