TMEM263
entrez
90488
canonical
uniprot
Q8WUH6
canonical
ensembl
ENSG00000151135
resolver
ensp
ENSP00000280756
resolver
ensp
ENSP00000446537
resolver
ensp
ENSP00000446717
resolver
ensp
ENSP00000449106
resolver
ensp
ENSP00000449785
resolver
ensp
ENSP00000450350
resolver
ensp
ENSP00000576403
resolver
ensp
ENSP00000576404
resolver
ensp
ENSP00000576405
resolver
ensp
ENSP00000576406
resolver
ensp
ENSP00000576407
resolver
ensp
ENSP00000576408
resolver
ensp
ENSP00000590930
resolver
ensp
ENSP00000590931
resolver
ensp
ENSP00000590932
resolver
ensp
ENSP00000632079
resolver
ensp
ENSP00000632081
resolver
ensp
ENSP00000632082
resolver
ensp
ENSP00000632083
resolver
enst
ENST00000280756
resolver
enst
ENST00000547081
resolver
enst
ENST00000547242
resolver
enst
ENST00000548125
resolver
enst
ENST00000550344
resolver
enst
ENST00000551813
resolver
enst
ENST00000906344
resolver
enst
ENST00000906345
resolver
enst
ENST00000906346
resolver
enst
ENST00000906347
resolver
enst
ENST00000906348
resolver
enst
ENST00000906349
resolver
enst
ENST00000920871
resolver
enst
ENST00000920872
resolver
enst
ENST00000920873
resolver
enst
ENST00000962020
resolver
enst
ENST00000962022
resolver
enst
ENST00000962023
resolver
enst
ENST00000962024
resolver
genesymbol
TMEM263
resolver
genesymbol_syn
C12orf23
resolver
hgnc
HGNC:28281
resolver
uniprot
B3KMN9
resolver
uniprot_entry
TM263_HUMAN
resolver
uniprot_sec
B3KMN9
resolver
amino_acid_sequence
MNQTDKNQQEIPSYLNDEPPEGSMKDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVTTVPSMGIGLVKGGVSAVAGGVTAVGSAVVNKVPLTGKKKDKSD
uniprot
proteins
disease_involvement
DISEASE: Note=Defect in TMEM263 has been found in a fetus with severe lethal skeletal dysplasia. The homozygous frameshift mutation found in this fetus results in the creation of a premature stop codon at Lys-68. {ECO:0000269|PubMed:34238371}.
uniprot
proteins
function
FUNCTION: May play a role in bone development. {ECO:0000269|PubMed:34238371}.
uniprot
proteins
mass_dalton
11748
uniprot
proteins
protein_family
TMEM263 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
34238371
uniprot
proteins
sequence_length
116
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 78..98; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins