RILPL2
entrez
196383
canonical
uniprot
Q969X0
canonical
ensembl
ENSG00000150977
resolver
ensp
ENSP00000280571
resolver
ensp
ENSP00000520842
resolver
ensp
ENSP00000520843
resolver
enst
ENST00000280571
resolver
enst
ENST00000718482
resolver
enst
ENST00000718483
resolver
genesymbol
RILPL2
resolver
genesymbol_syn
RLP2
resolver
hgnc
HGNC:28787
resolver
uniprot
A0ABB0MVH7
resolver
uniprot
A0ABB0MVJ7
resolver
uniprot_entry
A0ABB0MVH7_HUMAN
resolver
uniprot_entry
A0ABB0MVJ7_HUMAN
resolver
uniprot_entry
RIPL2_HUMAN
resolver
amino_acid_sequence
MEEPPVREEEEEEGEEDEERDEVGPEGALGKSPFQLTAEDVYDISYLLGRELMALGSDPRVTQLQFKVVRVLEMLEALVNEGSLALEELKMERDHLRKEVEGLRRQSPPASGEVNLGPNKMVVDLTDPNRPRFTLQELRDVLQERNKLKSQLLVVQEELQCYKSGLIPPREGPGGRREKDAVVTSAKNAGRNKEEKTIIKKLFFFRSGKQT
uniprot
proteins
function
FUNCTION: Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (By similarity). May function via activation of RAC1 and PAK1 (By similarity). {ECO:0000250|UniProtKB:Q6AYA0, ECO:0000250|UniProtKB:Q99LE1}.
uniprot
proteins
mass_dalton
23986
uniprot
proteins
mutagenesis
MUTAGEN 130; /note="R->E: Loss of interaction with RAB8A, RAB10 and RAB12."; /evidence="ECO:0000269|PubMed:29125462"; MUTAGEN 132; /note="R->E: Loss of interaction with RAB8A, RAB10 and RAB12."; /evidence="ECO:0000269|PubMed:29125462"; MUTAGEN 149; /note="K->E: Loss of interaction with RAB8A, RAB10 and RAB12."; /evidence="ECO:0000269|PubMed:29125462
uniprot
proteins
protein_family
RILPL family
uniprot
proteins
pubmed
14668488
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
29125462
uniprot
proteins
sequence_length
211
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:14668488}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell projection, cilium {ECO:0000250}.
uniprot
proteins