SNX11
entrez
29916
canonical
uniprot
Q9Y5W9
canonical
ensembl
ENSG00000002919
resolver
ensp
ENSP00000352175
resolver
ensp
ENSP00000377059
resolver
ensp
ENSP00000462188
resolver
ensp
ENSP00000463948
resolver
ensp
ENSP00000553878
resolver
ensp
ENSP00000553879
resolver
genesymbol
SNX11
resolver
hgnc
HGNC:14975
resolver
uniprot
B3KRL6
resolver
uniprot
B4DPY5
resolver
uniprot
D3DTV0
resolver
uniprot
Q53YC0
resolver
uniprot
Q9H885
resolver
uniprot_entry
SNX11_HUMAN
resolver
uniprot_sec
B3KRL6
resolver
uniprot_sec
B4DPY5
resolver
uniprot_sec
D3DTV0
resolver
uniprot_sec
Q53YC0
resolver
uniprot_sec
Q9H885
resolver
amino_acid_sequence
MGFWCRMSENQEQEEVITVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQLSVPEIEACVQGRSTMTVSDAILRYAMSNCGWAQEERQSSSHLAKGDQPKSCCFLPRSGRRSSPSPPPSEEKDHLEVWAPVVDSEVPSLESPTLPPLSSPLCCDFGRPKEGTSTLQSVRRAVGGDHAVPLDPGQLETVLEK
uniprot
proteins
function
FUNCTION: Phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes (PubMed:23615901). Regulates the levels of TRPV3 by promoting its trafficking from the cell membrane to lysosome for degradation (PubMed:26818531). {ECO:0000269|PubMed:23615901, ECO:0000269|PubMed:26818531}.
uniprot
proteins
mass_dalton
30433
uniprot
proteins
mutagenesis
MUTAGEN 59; /note="R->A: Abolishes lipid-binding."; /evidence="ECO:0000269|PubMed:23615901"; MUTAGEN 135..139; /note="IEACV->AAAAA: Impairs function in membrane trafficking."; /evidence="ECO:0000269|PubMed:23615901
uniprot
proteins
protein_family
Sorting nexin family
uniprot
proteins
pubmed
11485546
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
23615901
uniprot
proteins
pubmed
26818531
uniprot
proteins
sequence_length
270
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26818531}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Endosome {ECO:0000269|PubMed:23615901}. Cytoplasm {ECO:0000269|PubMed:26818531}.
uniprot
proteins