Rhog
entrez
56212
canonical
uniprot
P84096
canonical
ensembl
ENSMUSG00000073982
resolver
ensp
ENSMUSP00000095832
resolver
ensp
ENSMUSP00000102536
resolver
enst
ENSMUST00000098230
resolver
enst
ENSMUST00000106923
resolver
genesymbol
Rhog
resolver
genesymbol_syn
Arhg
resolver
genesymbol_syn
Sid10750
resolver
uniprot
P35238
resolver
uniprot
Q3UDZ1
resolver
uniprot
Q8NI04
resolver
uniprot_entry
Q3UDZ1_MOUSE
resolver
uniprot_entry
RHOG_MOUSE
resolver
uniprot_sec
P35238
resolver
uniprot_sec
Q8NI04
resolver
amino_acid_sequence
MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Plays a role in immunological synaptic F-actin density and architecture organization (By similarity). Regulates actin reorganization in lymphocytes, possibly through the modulation of Rac1 activity (By similarity). Acts as an activator of the ELMO-DOCK-Rac pathway (By similarity). Required for the formation of membrane ruffles during macropinocytosis (By similarity). Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes (By similarity). Binds phospholipids in an activation-dependent manner; thereby acting as an anchor for other proteins to the plasma membrane (PM) (By similarity). Plays a role in exocytosis of cytotoxic granules (CG) by lymphocytes/Component of the exocytosis machinery in natural killer (NK) and CD8+ T cells (By similarity). Promotes the docking of cytotoxic granules (CG) to the plasma membrane through the interaction with UNC13D (By similarity). Involved in the cytotoxic activity of lymphocytes/primary CD8+ T cells (By similarity). {ECO:0000250|UniProtKB:P84095}.
uniprot
proteins
mass_dalton
21309
uniprot
proteins
protein_family
Rho family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
32651375
uniprot
proteins
sequence_length
191
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins