Flrt2
entrez
299236
canonical
uniprot
D3ZTV3
canonical
ensembl
ENSRNOG00000003732
resolver
ensembl
ENSRNOG00055015467
resolver
ensembl
ENSRNOG00060004953
resolver
ensembl
ENSRNOG00065014295
resolver
ensp
ENSRNOP00000004955
resolver
ensp
ENSRNOP00000076725
resolver
ensp
ENSRNOP00000079728
resolver
ensp
ENSRNOP00000083901
resolver
ensp
ENSRNOP00000099707
resolver
ensp
ENSRNOP00000106525
resolver
ensp
ENSRNOP00000112796
resolver
ensp
ENSRNOP00055021439
resolver
ensp
ENSRNOP00055021443
resolver
ensp
ENSRNOP00055021446
resolver
ensp
ENSRNOP00055021447
resolver
ensp
ENSRNOP00060006209
resolver
ensp
ENSRNOP00060006215
resolver
ensp
ENSRNOP00060006216
resolver
ensp
ENSRNOP00060006217
resolver
ensp
ENSRNOP00065018332
resolver
ensp
ENSRNOP00065018335
resolver
ensp
ENSRNOP00065018339
resolver
ensp
ENSRNOP00065018342
resolver
enst
ENSRNOT00000004955
resolver
enst
ENSRNOT00000108960
resolver
enst
ENSRNOT00000113363
resolver
enst
ENSRNOT00000120043
resolver
enst
ENSRNOT00000139761
resolver
enst
ENSRNOT00000140813
resolver
enst
ENSRNOT00000173081
resolver
enst
ENSRNOT00055026387
resolver
enst
ENSRNOT00055026392
resolver
enst
ENSRNOT00055026395
resolver
enst
ENSRNOT00055026396
resolver
enst
ENSRNOT00060008260
resolver
enst
ENSRNOT00060008266
resolver
enst
ENSRNOT00060008268
resolver
enst
ENSRNOT00060008270
resolver
enst
ENSRNOT00065023570
resolver
enst
ENSRNOT00065023574
resolver
enst
ENSRNOT00065023579
resolver
enst
ENSRNOT00065023583
resolver
genesymbol
Flrt2
resolver
uniprot_entry
FLRT2_RAT
resolver
amino_acid_sequence
MGLQTAKWPSHGTFVLKFWLIMSLGLYSHVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIADGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSLNVRGFMCQGPEQVRGMAVRELNMNLLSCPTTTPGLPVFTPAPSTVSPTTQSPTVSVPSPSRGSVPPAPAPSKLPTIPDWDGRERATPPISERIQLSIHFVNDTSIQVSWLSLFTVMAYKLTWVKMGHSLVGGIVQERIVSGEKQHLSLVNLEPRSTYRICLVPLDAFNYRTVEDTICSEATTHASYLNNGSNTASSHEQTTSHTMGSPFLLAGLIGGAVIFVLVVLLSVFCWHMHKKGRYTSQKWKYNRGRRKDDYCEAGTKKDNSILEMTETSFQIVSLNNDQLLKGDFRLQPIYTPNGGINYTDCHIPNNMRYCNSSVPDLEHCHT
uniprot
proteins
function
FUNCTION: Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis. {ECO:0000250|UniProtKB:Q8BLU0}.
uniprot
proteins
mass_dalton
73874
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q8BLU0}.; PTM: Proteolytic cleavage in the juxtamembrane region gives rise to a soluble ectodomain. Cleavage is probably effected by a metalloprotease. {ECO:0000250|UniProtKB:Q8BLU0}.
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22405201
uniprot
proteins
sequence_length
660
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8BLU0}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q8BLU0}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8BLU0}. Synapse, synaptosome {ECO:0000269|PubMed:22405201}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q8BLU0}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q8BLU0}. Microsome membrane {ECO:0000250|UniProtKB:Q8BLU0}. Secreted {ECO:0000250|UniProtKB:Q8BLU0}. Note=Proteolytic cleavage gives rise to a shedded ectodomain. {ECO:0000250|UniProtKB:Q8BLU0}.
uniprot
proteins
transmembrane_region
TRANSMEM 541..561; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins