Lta
entrez
16992
canonical
uniprot
P09225
canonical
ensembl
ENSMUSG00000024402
resolver
ensp
ENSMUSP00000025266
resolver
ensp
ENSMUSP00000362914
resolver
enst
ENSMUST00000025266
resolver
genesymbol
Lta
resolver
genesymbol_syn
Tnfb
resolver
genesymbol_syn
Tnfsf1
resolver
genesymbol_syn
Tnlg1e
resolver
uniprot
Q542S2
resolver
uniprot_entry
Q542S2_MOUSE
resolver
uniprot_entry
TNFB_MOUSE
resolver
amino_acid_sequence
MTLLGRLHLLRVLGTPPVFLLGLLLALPLGAQGLSGVRFSAARTAHPLPQKHLTHGILKPAAHLVGYPSKQNSLLWRASTDRAFLRHGFSLSNNSLLIPTSGLYFVYSQVVFSGESCSPRAIPTPIYLAHEVQLFSSQYPFHVPLLSAQKSVYPGLQGPWVRSMYQGAVFLLSKGDQLSTHTDGISHLHFSPSSVFFGAFAL
uniprot
proteins
function
FUNCTION: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. {ECO:0000250|UniProtKB:P01374}.
uniprot
proteins
mass_dalton
21999
uniprot
proteins
protein_family
Tumor necrosis factor family
uniprot
proteins
pubmed
14656967
uniprot
proteins
pubmed
1700275
uniprot
proteins
pubmed
2884262
uniprot
proteins
pubmed
2885372
uniprot
proteins
pubmed
3147435
uniprot
proteins
pubmed
3490653
uniprot
proteins
pubmed
3588316
uniprot
proteins
pubmed
3684584
uniprot
proteins
sequence_length
202
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Membrane {ECO:0000250}. Note=The homotrimer is secreted. The heterotrimer is membrane-associated. {ECO:0000250}.
uniprot
proteins