Elmo1
entrez
140580
canonical
uniprot
Q8BPU7
canonical
ensembl
ENSMUSG00000041112
resolver
ensp
ENSMUSP00000072334
resolver
ensp
ENSMUSP00000160033
resolver
ensp
ENSMUSP00000309876
resolver
ensp
ENSMUSP00000309877
resolver
ensp
ENSMUSP00000309882
resolver
genesymbol
Elmo1
resolver
uniprot
Q8BSY9
resolver
uniprot
Q8K2C5
resolver
uniprot
Q91ZU3
resolver
uniprot_entry
ELMO1_MOUSE
resolver
uniprot_sec
Q8BSY9
resolver
uniprot_sec
Q8K2C5
resolver
uniprot_sec
Q91ZU3
resolver
amino_acid_sequence
MPPPSDIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRYIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN
uniprot
proteins
function
FUNCTION: Regulates the activity of DOCK guanine nucleotide exchange factors (GEFs). Acts in association with DOCK1, DOCK2 and CRK. Promotes RAC1 activation by DOCK5; the activity is stimulated by RHOG. Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. {ECO:0000250|UniProtKB:Q92556}.
uniprot
proteins
mass_dalton
83936
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by HCK. {ECO:0000250}.
uniprot
proteins
pubmed
11595183
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17960134
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27505886
uniprot
proteins
sequence_length
727
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK. {ECO:0000250}.
uniprot
proteins