ERAS
entrez
3266
canonical
uniprot
Q7Z444
canonical
ensembl
ENSG00000187682
resolver
ensp
ENSP00000339136
resolver
ensp
ENSP00000490793
resolver
enst
ENST00000338270
resolver
enst
ENST00000636362
resolver
genesymbol
ERAS
resolver
genesymbol_syn
HRAS2
resolver
genesymbol_syn
HRASP
resolver
hgnc
HGNC:5174
resolver
uniprot_entry
RASE_HUMAN
resolver
activity_regulation
ACTIVITY REGULATION: Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).
uniprot
proteins
amino_acid_sequence
MELPTKPGTFDLGLATWSPSFQGETHRAQARRRDVGRQLPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQAIHRALRDQCLAVCDGVLGVFALDDPSSLIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDAHAAAAALAHSWGAHFVETSAKTRQGVEEAFSLLVHEIQRVQEAMAKEPMARSCREKTRHQKATCHCGCSVA
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
25287
uniprot
proteins
protein_family
Ras family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
12774123
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
uniprot
proteins