Cd55
entrez
13136
canonical
uniprot
Q61475
canonical
ensembl
ENSMUSG00000026399
resolver
ensp
ENSMUSP00000027650
resolver
ensp
ENSMUSP00000163434
resolver
ensp
ENSMUSP00000163435
resolver
enst
ENSMUST00000027650
resolver
genesymbol
Cd55
resolver
genesymbol_syn
Cd55a
resolver
genesymbol_syn
Daf
resolver
genesymbol_syn
Daf1
resolver
uniprot
P97732
resolver
uniprot
Q3TU32
resolver
uniprot
Q4FJS4
resolver
uniprot
Q61397
resolver
uniprot
Q76N72
resolver
uniprot
Q921P0
resolver
uniprot
Q9R1C1
resolver
uniprot_entry
DAF1_MOUSE
resolver
uniprot_sec
P97732
resolver
uniprot_sec
Q3TU32
resolver
uniprot_sec
Q4FJS4
resolver
uniprot_sec
Q61397
resolver
uniprot_sec
Q76N72
resolver
uniprot_sec
Q921P0
resolver
uniprot_sec
Q9R1C1
resolver
amino_acid_sequence
MIRGRAPRTRPSPPPPLLPLLSLSLLLLSPTVRGDCGPPPDIPNARPILGRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWSSHETFCEKSCVAPERLSFASLKKEYLNMNFFPVGTIVEYECRPGFRKQPPLPGKATCLEDLVWSPVAQFCKKKSCPNPKDLDNGHINIPTGILFGSEINFSCNPGYRLVGVSSTFCSVTGNTVDWDDEFPVCTEIHCPEPPKINNGIMRGESDSYTYSQVVTYSCDKGFILVGNASIYCTVSKSDVGQWSSPPPRCIEKSKVPTKKPTINVPSTGTPSTPQKPTTESVPNPGDQPTPQKPSTVKVSATQHVPVTKTTVRHPIRTSTDKGEPNTGGDRYIYGHTCLITLTVLHVMLSLIGYLT
uniprot
proteins
function
FUNCTION: This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. {ECO:0000250|UniProtKB:P08174}.
uniprot
proteins
mass_dalton
42618
uniprot
proteins
protein_family
Receptors of complement activation (RCA) family
uniprot
proteins
pubmed
10417349
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7545711
uniprot
proteins
pubmed
8671624
uniprot
proteins
pubmed
9435343
uniprot
proteins
sequence_length
390
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
uniprot
proteins