Frmd4b
entrez
232288
canonical
uniprot
Q920B0
canonical
ensembl
ENSMUSG00000030064
resolver
ensp
ENSMUSP00000032146
resolver
ensp
ENSMUSP00000108982
resolver
ensp
ENSMUSP00000108986
resolver
ensp
ENSMUSP00000285588
resolver
enst
ENSMUST00000113359
resolver
genesymbol
Frmd4b
resolver
genesymbol_syn
mKIAA1013
resolver
uniprot
F6ZNP9
resolver
uniprot
Q3V1S1
resolver
uniprot
Q6ZQ04
resolver
uniprot
Q8C0E8
resolver
uniprot
Q920B1
resolver
uniprot
Q9ESP9
resolver
uniprot_entry
F6ZNP9_MOUSE
resolver
uniprot_entry
FRM4B_MOUSE
resolver
uniprot_entry
Q6ZQ04_MOUSE
resolver
uniprot_entry
Q8C0E8_MOUSE
resolver
uniprot_sec
Q3V1S1
resolver
uniprot_sec
Q920B1
resolver
uniprot_sec
Q9ESP9
resolver
amino_acid_sequence
MASVFMCGVEDLLFSGSRFVWNLTVSTLRRWYTERLRACHQVLRTWCGLRDVYQMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPTLLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRGSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLQKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDDPNDSFTLAGQRPSSVPHSPRILPPKSLGIERIHFRKSSINEQFMDTRHSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAASPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDPLRNGVYSKGQDPPPSGYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYRSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPRKAAVKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSEYENPVHSPYTSYYGSIYNPLSSPSRQYAETTPLDGTDGSQLEDNLEGSEQRLFWHEDSKPGTLV
uniprot
proteins
function
FUNCTION: Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (PubMed:20080746). Plays a redundant role with FRMD4A in epithelial polarization (PubMed:20080746). {ECO:0000269|PubMed:20080746}.
uniprot
proteins
mass_dalton
118007
uniprot
proteins
pubmed
11445584
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
20080746
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1035
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11445584}. Cell junction, tight junction {ECO:0000269|PubMed:20080746}. Cell junction, adherens junction {ECO:0000269|PubMed:20080746}. Note=Colocalized with PARD3 at adherens junction and tight junction (PubMed:20080746). {ECO:0000269|PubMed:20080746}.
uniprot
proteins