Pdxk
entrez
216134
canonical
uniprot
Q8K183
canonical
ensembl
ENSMUSG00000032788
resolver
ensp
ENSMUSP00000038540
resolver
enst
ENSMUST00000041616
resolver
genesymbol
Pdxk
resolver
genesymbol_syn
Pkh
resolver
uniprot
Q3TM83
resolver
uniprot
Q8BJQ5
resolver
uniprot_entry
PDXK_MOUSE
resolver
uniprot_sec
Q3TM83
resolver
uniprot_sec
Q8BJQ5
resolver
activity_regulation
ACTIVITY REGULATION: Activity is increased in the presence of K(+)or Na(+). {ECO:0000250|UniProtKB:O00764}.
uniprot
proteins
amino_acid_sequence
MEGECRVLSIQSHVVRGYVGNRAAMFPLQVLGFEVDAVNSVQFSNHTGYAHWKGQVLKSQELHELYEGLKVNDVNKYDYVLTGYTRDKSFLAMVVDIVRELKQQNSRLVYVCDPVMGDKWNGEGSMYVPQDLLPVYRDKVVPVADIITPNQFEAELLSGRKIHSQEEAFEVMDMLHCMGPDTVVITSSDLPSSQGSDYLIALGSQRMRKPDGSTVTQRIRMEMRKVEAVFVGTGDLFAAMLLAWTHKHPDNLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSPAQLELRMVQSKRDIEDPEIVVQATVL
uniprot
proteins
ec_number
2.7.1.35
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (By similarity). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions (By similarity). {ECO:0000250|UniProtKB:O00764}.
uniprot
proteins
mass_dalton
35015
uniprot
proteins
pathway_participation
PATHWAY: Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxal: step 1/1. {ECO:0000250|UniProtKB:O00764}.; PATHWAY: Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxine 5'-phosphate from pyridoxine: step 1/1. {ECO:0000250|UniProtKB:O00764}.; PATHWAY: Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxamine 5'-phosphate from pyridoxamine: step 1/1. {ECO:0000250|UniProtKB:O00764}.
uniprot
proteins
protein_family
Pyridoxine kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
312
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:O00764}.
uniprot
proteins