Meiob
entrez
685099
canonical
uniprot
B0BMX9
canonical
ensembl
ENSRNOG00000014711
resolver
ensembl
ENSRNOG00055023617
resolver
ensembl
ENSRNOG00060007037
resolver
ensembl
ENSRNOG00065009296
resolver
ensp
ENSRNOP00000057290
resolver
ensp
ENSRNOP00000082963
resolver
ensp
ENSRNOP00055032974
resolver
ensp
ENSRNOP00060008681
resolver
ensp
ENSRNOP00065011105
resolver
enst
ENSRNOT00000060551
resolver
enst
ENSRNOT00055040586
resolver
enst
ENSRNOT00060011561
resolver
enst
ENSRNOT00065014856
resolver
genesymbol
Meiob
resolver
uniprot_entry
MEIOB_RAT
resolver
amino_acid_sequence
MAKFFALKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPNHFVNVSSWGSEDYIRSLSDNFKVGECVIIENPLIQRKETEREERFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLFDETEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANILLNFIRENKETSIADEIDSYLKESVNLNTIVNVYTVEQLKGKALENEGKVDPFYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNDASNTCTICSKDSSRSRSFCLSFDVLVDLTDHTGTLRSCSLSGSVAEETLGCTINEFLTMTSEQKTKLKWQLLLERSKIYLKLILSHRARGGLKVTILSCKLADPIEASRDLAGQGHT
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro. {ECO:0000250|UniProtKB:Q9D513}.
uniprot
proteins
mass_dalton
52819
uniprot
proteins
protein_family
MEIOB family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
470
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9D513}. Nucleus {ECO:0000250|UniProtKB:Q9D513}. Chromosome {ECO:0000250|UniProtKB:Q9D513}. Note=Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on SPATA22. {ECO:0000250|UniProtKB:Q9D513}.
uniprot
proteins