HEL-S-18
entrez
85413
canonical
uniprot
Q86VW1
canonical
ensembl
ENSG00000004809
resolver
ensp
ENSP00000357915
resolver
ensp
ENSP00000395642
resolver
ensp
ENSP00000416310
resolver
ensp
ENSP00000611136
resolver
ensp
ENSP00000611137
resolver
genesymbol
HEL-S-18
resolver
genesymbol
SLC22A16
resolver
genesymbol_syn
OCT6
resolver
hgnc
HGNC:20302
resolver
uniprot
A0A0K0K1K9
resolver
uniprot
O14567
resolver
uniprot
Q5JXM1
resolver
uniprot
Q8IUG8
resolver
uniprot
Q8IZD5
resolver
uniprot
Q96M90
resolver
uniprot
Q96RU0
resolver
uniprot_entry
A0A0K0K1K9_HUMAN
resolver
uniprot_entry
S22AG_HUMAN
resolver
uniprot_sec
O14567
resolver
uniprot_sec
Q5JXM1
resolver
uniprot_sec
Q8IUG8
resolver
uniprot_sec
Q8IZD5
resolver
uniprot_sec
Q96M90
resolver
uniprot_sec
Q96RU0
resolver
amino_acid_sequence
MGSRHFEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNSGLEKTEAITPRDSGLGE
uniprot
proteins
function
FUNCTION: Facilitative organic cation transporter that mediates the transport of carnitine as well as the polyamine spermidine (PubMed:12089149, PubMed:20037140). Mediates the partially Na(+)-dependent bidirectional transport of carnitine (PubMed:12089149). May mediate L-carnitine secretion from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa (PubMed:12089149). {ECO:0000269|PubMed:12089149, ECO:0000269|PubMed:20037140}.
uniprot
proteins
mass_dalton
64614
uniprot
proteins
protein_family
Major facilitator (TC 2.A.1) superfamily
uniprot
proteins
protein_family
Organic cation transporter (TC 2.A.1.19) family
uniprot
proteins
pubmed
12089149
uniprot
proteins
pubmed
12372408
uniprot
proteins
pubmed
12384147
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15963465
uniprot
proteins
pubmed
17197897
uniprot
proteins
pubmed
17581421
uniprot
proteins
pubmed
20037140
uniprot
proteins
sequence_length
577
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12089149, ECO:0000269|PubMed:20037140}; Multi-pass membrane protein {ECO:0000305}. Note=Detected in the plasma membrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis. {ECO:0000269|PubMed:12089149}.
uniprot
proteins
transmembrane_region
TRANSMEM 23..43; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 152..172; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 183..203; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 214..234; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 244..264; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 268..288; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 359..379; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 389..409; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 416..436; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 441..461; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 476..496; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 501..521; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins