Fshb
entrez
14308
canonical
uniprot
Q60687
canonical
ensembl
ENSMUSG00000027120
resolver
ensp
ENSMUSP00000028533
resolver
enst
ENSMUST00000028533
resolver
genesymbol
Fshb
resolver
uniprot_entry
FSHB_MOUSE
resolver
amino_acid_sequence
MMKLIQLCILFWCWRAICCHSCELTNITISVEKEECRFCISINTTWCAGYCYTRDLVYKDPARPNTQKVCTFKELVYETVRLPGCARHSDSLYTYPVATECHCGKCDSDSTDCTVRGLGPSYCSFSEMKE
uniprot
proteins
function
FUNCTION: Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (By similarity). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:11416011, PubMed:9020850). {ECO:0000250|UniProtKB:P01225, ECO:0000269|PubMed:11416011, ECO:0000269|PubMed:9020850}.
uniprot
proteins
mass_dalton
14919
uniprot
proteins
protein_family
Glycoprotein hormones subunit beta family
uniprot
proteins
pubmed
11416011
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
23371388
uniprot
proteins
pubmed
8543187
uniprot
proteins
pubmed
9020850
uniprot
proteins
sequence_length
130
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P01225}. Note=Efficient secretion requires dimerization with CGA. {ECO:0000250|UniProtKB:P01225}.
uniprot
proteins