Rxfp2
entrez
140498
canonical
uniprot
Q91ZZ5
canonical
ensembl
ENSMUSG00000053368
resolver
ensp
ENSMUSP00000067897
resolver
ensp
ENSMUSP00000106122
resolver
ensp
ENSMUSP00000144536
resolver
enst
ENSMUST00000065745
resolver
enst
ENSMUST00000110496
resolver
enst
ENSMUST00000201612
resolver
genesymbol
Rxfp2
resolver
genesymbol_syn
Gpr106
resolver
genesymbol_syn
Great
resolver
genesymbol_syn
Lgr8
resolver
uniprot
A0A0J9YV81
resolver
uniprot
B7ZMU5
resolver
uniprot
E9Q0U9
resolver
uniprot
Q0VB90
resolver
uniprot_entry
A0A0J9YV81_MOUSE
resolver
uniprot_entry
B7ZMU5_MOUSE
resolver
uniprot_entry
E9Q0U9_MOUSE
resolver
uniprot_entry
RXFP2_MOUSE
resolver
uniprot_sec
Q0VB90
resolver
amino_acid_sequence
MWLLLHVILLTEVKDFALADSSMVAPLCPKGYFPCGNLTKCLPRAFHCDGVDDCGNGADEDNCGDTSGWTTIFGTVHGNVNKVTLTQECFLSQYPQHCYCRENELECVKADLKAVPKVSSNVTLLSLKKNKIHRLPVKVFSRYTELRKIYLQHNCITHISRRAFLGLHNLQILYLSHNCITSLRPGIFKDLHQLAWLILDDNPITRISQKSFMGLNSLFFLSMVGNRLEALPETLCAQMPQLNWVDLANNGIKYITNSTFLTCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNMITKLPVHLFSDLHLLQKLNLSSNPLLYVHKNQFGSLKQLQSLDLERIEIPNISTGMFQPMKNLSHIYLKTFRYCSYVPHVRICMPSTDGISSSEDLLANGILRVSVWVIAFITCVGNFLVIAVRSLIKAENTTHAMSIKILCCADCLMGVYLFSVGVFDIKYRGQYQKYALLWMESVPCRLLGFLATLSTEVSVLLLTFLTLEKFLVIVFPFSNLRLGKRQTAVALASIWVVGFLIAAVPFTREDYFGNFYGKNGVCFPLHYDQAEDFGSRGYSLGIFLGVNLLAFLVIVISYVTMFCSIHKTALQTAEVRSHIGKEVAVANRFFFIVFSDAICWIPVFVVKILSLLQVEIPGTITSWIVVFFLPVNSALNPILYTLTTSFFKDKLKQLLHKHRRKPIFKVKKKSLSASIVWTDESSLKLGVLSKIALGDSIMKPVSP
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Rxfp2 seems to be a cause of impaired testicular descent (known as cryptorchidism). {ECO:0000305|PubMed:11353515}.
uniprot
proteins
function
FUNCTION: Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3) (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
82934
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11353515
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
737
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 400..420; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 439..459; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 479..501; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 521..541; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 576..596; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 623..643; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 654..674; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins