B3gnt7
entrez
227327
canonical
uniprot
Q8K0J2
canonical
ensembl
ENSMUSG00000079445
resolver
ensp
ENSMUSP00000108931
resolver
enst
ENSMUST00000113306
resolver
genesymbol
B3gnt7
resolver
uniprot
Q3U3L9
resolver
uniprot
Q3V283
resolver
uniprot
Q6PA02
resolver
uniprot
Q8BJS5
resolver
uniprot
Q8K437
resolver
uniprot_entry
B3GN7_MOUSE
resolver
uniprot_sec
Q3U3L9
resolver
uniprot_sec
Q3V283
resolver
uniprot_sec
Q6PA02
resolver
uniprot_sec
Q8BJS5
resolver
uniprot_sec
Q8K437
resolver
amino_acid_sequence
MSLWKKTLYKSVCLALALLVAVTVFQRSVTPGQFLQDPLPPTPGPAKTGNLVNPNSFWKSSKDVAAPTPTVPRGPQVWDVITTNCSININLTHQPWFQSLEPHFRQFLAYRHCRYFPMLLNHPEKCAGDVYMLVVVKSVITQHDRREVIRQTWGHEWESAGLGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYADILQWDFLDSFFNLTLKEIHFLKWLDIYCPNVPFVFKGDDDVFVNPTNLLEFLSDRQPQENLFVGDVLKHARPIRKKDNKYYIPAVMYGKATYPPYAGGGGFLMSGSLARQLHHACDTLELFPIDDVFLGMCLEVLGVKPTGHEGFKTFGISRVRSSRMNKEPCFYRAMLVVHKLLPAELLAMWDLVHSNLTCSVKFQVL
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
function
FUNCTION: N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer (By similarity). Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (PubMed:29625490). May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (PubMed:12061784). {ECO:0000250|UniProtKB:Q8NFL0, ECO:0000269|PubMed:12061784, ECO:0000269|PubMed:29625490}.
uniprot
proteins
mass_dalton
45379
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q8NFL0}.
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
12061784
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
29625490
uniprot
proteins
sequence_length
397
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..26; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins