Ddx49
entrez
234374
canonical
uniprot
Q4FZF3
canonical
ensembl
ENSMUSG00000057788
resolver
ensp
ENSMUSP00000008004
resolver
enst
ENSMUST00000008004
resolver
genesymbol
Ddx49
resolver
uniprot_entry
DDX49_MOUSE
resolver
amino_acid_sequence
MAGFAEIGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSSNTFNMKKIQFLVMDEADRLLEQGCTDFTTDLETILAAVPARRQTLLFSATLTDTLKELQGLATNEPFFWEAQATVRTVEQLDQRYLLVPEKVKDAYLVHLVQTFQDQLEDCSIIIFTNTCKTCQILCMMLRKFNFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLLHAIEEQIKQQLAELVVEEAEVLQILTQVNVVRRECEIKLEASHFDEKKEINKRKQMILEGKDPDLEAKRKAELAKIKQQNRRFKEKVGQTLRRQKAGSTVRRSRPPRSRPQEPAQAEAQD
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: ATP-dependent RNA helicase that plays a role in various aspects of RNA metabolism including the regulation of mRNA export and the levels of pre-ribosomal RNA. Regulates the stability and synthesis of pre-ribosomal RNA and thereby regulates cell proliferation. Also possesses antiviral activity by recognizing gammaherpesvirus transcripts in the context of lytic reactivation. {ECO:0000250|UniProtKB:Q9Y6V7}.
uniprot
proteins
mass_dalton
54094
uniprot
proteins
protein_family
DDX49/DBP8 subfamily
uniprot
proteins
protein_family
DEAD box helicase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
480
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9Y6V7}.
uniprot
proteins