SERPINA10
entrez
51156
canonical
uniprot
Q9UK55
canonical
ensembl
ENSG00000140093
resolver
ensembl
ENSG00000278767
resolver
ensp
ENSP00000261994
resolver
ensp
ENSP00000376809
resolver
ensp
ENSP00000450896
resolver
ensp
ENSP00000450971
resolver
ensp
ENSP00000482029
resolver
ensp
ENSP00000484632
resolver
ensp
ENSP00000573676
resolver
ensp
ENSP00000573678
resolver
ensp
ENSP00000573679
resolver
ensp
ENSP00000573681
resolver
ensp
ENSP00000573682
resolver
ensp
ENSP00000573683
resolver
ensp
ENSP00000573684
resolver
ensp
ENSP00000573685
resolver
ensp
ENSP00000573686
resolver
ensp
ENSP00000573687
resolver
ensp
ENSP00000573688
resolver
ensp
ENSP00000573689
resolver
ensp
ENSP00000613613
resolver
ensp
ENSP00000613614
resolver
enst
ENST00000261994
resolver
enst
ENST00000393096
resolver
enst
ENST00000554173
resolver
enst
ENST00000554723
resolver
enst
ENST00000614630
resolver
enst
ENST00000616057
resolver
enst
ENST00000903617
resolver
enst
ENST00000903619
resolver
enst
ENST00000903620
resolver
enst
ENST00000903622
resolver
enst
ENST00000903623
resolver
enst
ENST00000903624
resolver
enst
ENST00000903625
resolver
enst
ENST00000903626
resolver
enst
ENST00000903627
resolver
enst
ENST00000903628
resolver
enst
ENST00000903629
resolver
enst
ENST00000903630
resolver
enst
ENST00000943554
resolver
enst
ENST00000943555
resolver
genesymbol
SERPINA10
resolver
genesymbol_syn
ZPI
resolver
hgnc
HGNC:15996
resolver
uniprot
A5Z2A5
resolver
uniprot
G3V2W1
resolver
uniprot
Q6UWX9
resolver
uniprot
Q86U20
resolver
uniprot_entry
G3V2W1_HUMAN
resolver
uniprot_entry
ZPI_HUMAN
resolver
uniprot_sec
A5Z2A5
resolver
uniprot_sec
Q6UWX9
resolver
uniprot_sec
Q86U20
resolver
amino_acid_sequence
MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL
uniprot
proteins
function
FUNCTION: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. {ECO:0000269|PubMed:11049983}.
uniprot
proteins
mass_dalton
50707
uniprot
proteins
mutagenesis
MUTAGEN 408; /note="Y->A: Loss of inhibitory activity."; /evidence="ECO:0000269|PubMed:10460162
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by FAM20C in the extracellular medium. {ECO:0000269|PubMed:26091039}.
uniprot
proteins
protein_family
Serpin family
uniprot
proteins
pubmed
10460162
uniprot
proteins
pubmed
11049983
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
19528533
uniprot
proteins
pubmed
20427285
uniprot
proteins
pubmed
22540147
uniprot
proteins
pubmed
23375655
uniprot
proteins
pubmed
26091039
uniprot
proteins
pubmed
9689066
uniprot
proteins
sequence_length
444
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins