CIBAR2
entrez
339145
canonical
uniprot
Q6ZTR7
canonical
ensembl
ENSG00000153789
resolver
ensp
ENSP00000443411
resolver
enst
ENST00000539556
resolver
genesymbol
CIBAR2
resolver
genesymbol_syn
FAM92B
resolver
hgnc
HGNC:24781
resolver
uniprot
A0A0D9SG36
resolver
uniprot
A0A1X7SC74
resolver
uniprot_entry
CBAR2_HUMAN
resolver
uniprot_sec
A0A0D9SG36
resolver
uniprot_sec
A0A1X7SC74
resolver
amino_acid_sequence
MNIVFSRDSQVRVMENTVANTEKYFGQFCSLLAAYTRKTARLRDKADQLVKQLIDFANSENPELRATMRGFAEDLAKVQDYRQAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKLEKLRQKSPSDQQMISQAETRVQRAAVDSSRTTLQLEETVDGFQRQKLKDLQKFFCDFVTIEMVFHAKAVEVYSSAFQTLEKYDLERDLLDFRAKMQGVYGHYDTRLLANTSPPPSVLQSLASQGTLQVQLSRANEDPEHPHANHGRFSLCEWVVKGQPAHCVCGQGGHLMLPGHSL
uniprot
proteins
function
FUNCTION: May play a role in ciliogenesis (By similarity). In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis (PubMed:27528616). {ECO:0000250|UniProtKB:A1XBS5, ECO:0000269|PubMed:27528616}.
uniprot
proteins
mass_dalton
34785
uniprot
proteins
mutagenesis
MUTAGEN 105; /note="K->E: Abolishes ability to induce membrane remodeling in the presence of CBY1; when associated with E-108; E-112; E-130; E-132 and E-134."; /evidence="ECO:0000269|PubMed:27528616"; MUTAGEN 108; /note="R->E: Abolishes ability to induce membrane remodeling in the presence of CBY1; when associated with E-105; E-112; E-130; E-132 and E-134."; /evidence="ECO:0000269|PubMed:27528616"; MUTAGEN 112; /note="K->E: Abolishes ability to induce membrane remodeling in the presence of CBY1; when associated with E-105; E-108; E-130; E-132 and E-134."; /evidence="ECO:0000269|PubMed:27528616"; MUTAGEN 130; /note="K->E: Abolishes ability to induce membrane remodeling in the presence of CBY1; when associated with E-105; E-108; E-112; E-132 and E-134."; /evidence="ECO:0000269|PubMed:27528616"; MUTAGEN 132; /note="R->E: Abolishes ability to induce membrane remodeling in the presence of CBY1; when associated with E-105; E-108; E-112; E-130 and E-134."; /evidence="ECO:0000269|PubMed:27528616"; MUTAGEN 134; /note="K->E: Abolishes ability to induce membrane remodeling in the presence of CBY1; when associated with E-105; E-108; E-1112; E-130 and E-132."; /evidence="ECO:0000269|PubMed:27528616
uniprot
proteins
protein_family
CIBAR family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
27528616
uniprot
proteins
sequence_length
304
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q3V2J0}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q3V2J0}. Note=Extensive colocalization with CBY1 at mother centrioles. {ECO:0000250|UniProtKB:Q3V2J0}.
uniprot
proteins