ATG101
entrez
60673
canonical
uniprot
Q9BSB4
canonical
ensembl
ENSG00000123395
resolver
ensp
ENSP00000338990
resolver
ensp
ENSP00000450088
resolver
ensp
ENSP00000578736
resolver
ensp
ENSP00000578737
resolver
ensp
ENSP00000608107
resolver
ensp
ENSP00000608108
resolver
ensp
ENSP00000608109
resolver
ensp
ENSP00000608110
resolver
ensp
ENSP00000608111
resolver
ensp
ENSP00000608112
resolver
enst
ENST00000336854
resolver
enst
ENST00000908677
resolver
enst
ENST00000908678
resolver
enst
ENST00000938048
resolver
enst
ENST00000938049
resolver
enst
ENST00000938050
resolver
enst
ENST00000938051
resolver
enst
ENST00000938052
resolver
enst
ENST00000938053
resolver
genesymbol
ATG101
resolver
genesymbol_syn
C12orf44
resolver
hgnc
HGNC:25679
resolver
uniprot
Q9HAE2
resolver
uniprot
Q9HBN1
resolver
uniprot_entry
ATGA1_HUMAN
resolver
uniprot_sec
Q9HAE2
resolver
uniprot_sec
Q9HBN1
resolver
amino_acid_sequence
MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITDALGTSVTTTMRRLIKDTLAL
uniprot
proteins
function
FUNCTION: Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation. {ECO:0000269|PubMed:19287211, ECO:0000269|PubMed:19597335}.
uniprot
proteins
mass_dalton
25003
uniprot
proteins
mutagenesis
MUTAGEN 31; /note="H->S: Impairs interaction with ATG13; when associated with R-54."; /evidence="ECO:0000269|PubMed:26299944"; MUTAGEN 54; /note="D->R: Impairs interaction with ATG13; when associated with S-31."; /evidence="ECO:0000269|PubMed:26299944"; MUTAGEN 152; /note="I->D: Abolishes interaction with ATG13; when associated with D-153 and D-156."; /evidence="ECO:0000269|PubMed:26299944"; MUTAGEN 153; /note="I->D: Abolishes interaction with ATG13; when associated with D-152 and D-156."; /evidence="ECO:0000269|PubMed:26299944"; MUTAGEN 156; /note="V->D: Abolishes interaction with ATG13; when associated with D-152 and D-152."; /evidence="ECO:0000269|PubMed:26299944
uniprot
proteins
protein_family
ATG101 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15498874
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
19287211
uniprot
proteins
pubmed
19597335
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
26236954
uniprot
proteins
pubmed
26299944
uniprot
proteins
sequence_length
218
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19597335}. Preautophagosomal structure {ECO:0000269|PubMed:19597335}. Note=Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. {ECO:0000269|PubMed:19597335}.
uniprot
proteins