LRRC14
entrez
9684
canonical
uniprot
Q15048
canonical
ensembl
ENSG00000160959
resolver
ensp
ENSP00000292524
resolver
ensp
ENSP00000434768
resolver
ensp
ENSP00000557410
resolver
ensp
ENSP00000597436
resolver
ensp
ENSP00000597437
resolver
ensp
ENSP00000597438
resolver
ensp
ENSP00000623122
resolver
ensp
ENSP00000623123
resolver
ensp
ENSP00000623124
resolver
ensp
ENSP00000623125
resolver
ensp
ENSP00000623126
resolver
ensp
ENSP00000623127
resolver
enst
ENST00000292524
resolver
enst
ENST00000529022
resolver
enst
ENST00000887351
resolver
enst
ENST00000927377
resolver
enst
ENST00000927378
resolver
enst
ENST00000927379
resolver
enst
ENST00000953063
resolver
enst
ENST00000953064
resolver
enst
ENST00000953065
resolver
enst
ENST00000953066
resolver
enst
ENST00000953067
resolver
enst
ENST00000953068
resolver
genesymbol
LRRC14
resolver
genesymbol_syn
KIAA0014
resolver
hgnc
HGNC:20419
resolver
uniprot
A8K0A8
resolver
uniprot
D3DWM8
resolver
uniprot_entry
LRC14_HUMAN
resolver
uniprot_sec
A8K0A8
resolver
uniprot_sec
D3DWM8
resolver
amino_acid_sequence
MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTVVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERPSTESMQAVILGLTARLHTSEPGASTQPLCRKHALRVLDMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQGGAAEPGPAPIPVEVRVDLRVNRASYAFLREALRSSVGSPLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRVDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFTCLRELSMGSSLLSGRLDQLLSTLQSPLESLELAFCALLPEDLRFLARSPHAAHLKKLDLSGNDLSGSQLAPFQGLLQASAATLLHLELTECQLADTQLLATLPILTQCASLRYLGLYGNPLSMAGLKELLRDSVAQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFSL
uniprot
proteins
function
FUNCTION: Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB. {ECO:0000269|PubMed:27426725}.
uniprot
proteins
mass_dalton
54513
uniprot
proteins
protein_family
LRRC14 subfamily
uniprot
proteins
protein_family
PRAME family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27426725
uniprot
proteins
pubmed
7584026
uniprot
proteins
sequence_length
493
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27426725}.
uniprot
proteins