ARID3A
entrez
1820
canonical
uniprot
Q99856
canonical
ensembl
ENSG00000116017
resolver
ensp
ENSP00000263620
resolver
ensp
ENSP00000522957
resolver
ensp
ENSP00000607860
resolver
ensp
ENSP00000607861
resolver
enst
ENST00000263620
resolver
enst
ENST00000852898
resolver
enst
ENST00000937801
resolver
enst
ENST00000937802
resolver
genesymbol
ARID3A
resolver
genesymbol_syn
DRIL1
resolver
genesymbol_syn
DRIL3
resolver
genesymbol_syn
DRX
resolver
genesymbol_syn
E2FBP1
resolver
hgnc
HGNC:3031
resolver
uniprot
Q5I858
resolver
uniprot
Q6P9C6
resolver
uniprot
Q8IZA7
resolver
uniprot
Q8N4Z3
resolver
uniprot_entry
ARI3A_HUMAN
resolver
uniprot_sec
Q5I858
resolver
uniprot_sec
Q6P9C6
resolver
uniprot_sec
Q8IZA7
resolver
uniprot_sec
Q8N4Z3
resolver
amino_acid_sequence
MKLQAVMETLLQRQQRARQELEARQQLPPDPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASPGGSEDGPPGSEEEDAAREGTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGEDEEEEEEDYEDEEEEEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGVPRVLGGQERPGPGPAHPGGAAHVAPQLQPPDHGDWTYEEQFKQLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP
uniprot
proteins
function
FUNCTION: Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. {ECO:0000269|PubMed:11812999, ECO:0000269|PubMed:12692263}.
uniprot
proteins
mass_dalton
62889
uniprot
proteins
mutagenesis
MUTAGEN 325; /note="Y->A: Abolishes DNA-binding."; /evidence="ECO:0000269|PubMed:16738337"; MUTAGEN 461; /note="K->A: Abolishes nuclear targeting."; /evidence="ECO:0000269|PubMed:17400556"; MUTAGEN 527; /note="G->A,P: Impairs DNA-binding but not self-association."; /evidence="ECO:0000269|PubMed:17400556"; MUTAGEN 530; /note="Y->A: Impairs DNA-binding but not self-association."; /evidence="ECO:0000269|PubMed:17400556"; MUTAGEN 530; /note="Y->F: No effect on DNA-binding."; /evidence="ECO:0000269|PubMed:17400556"; MUTAGEN 532; /note="G->A: Impairs DNA-binding."; /evidence="ECO:0000269|PubMed:17400556"; MUTAGEN 534; /note="L->A: Impairs DNA-binding."; /evidence="ECO:0000269|PubMed:17400556
uniprot
proteins
pubmed
11812999
uniprot
proteins
pubmed
12692263
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16738337
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17400556
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20455271
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
9722953
uniprot
proteins
pubmed
9780002
uniprot
proteins
sequence_length
593
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000269|PubMed:17400556}. Cytoplasm {ECO:0000269|PubMed:17400556}. Note=Shuttles between nucleus and cytoplasm.
uniprot
proteins