Hsd17b1
entrez
15485
canonical
uniprot
P51656
canonical
ensembl
ENSMUSG00000019301
resolver
ensp
ENSMUSP00000019445
resolver
enst
ENSMUST00000019445
resolver
genesymbol
Hsd17b1
resolver
genesymbol_syn
Edh17b1
resolver
uniprot
Q790P4
resolver
uniprot_entry
DHB1_MOUSE
resolver
uniprot_entry
Q790P4_MOUSE
resolver
amino_acid_sequence
MDPTVVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGSLEILELDVRDSKSVAAAQACVTEGRVDVLVCNAGRGLFGPLEAHELNAVGAVLDVNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVHVSLIECGAVHTAFYEKLVGGPGGALERADAQTRHLFAHYLRGYEQALSEAQDPEEVTELFLTAMRAPQPALRYFSTNRFLPLARMRTEDPSGSSYVAAMHQEAFSNLQTQENAKAGAQVPGVSDTASSALICLPECAIPRVASELGWSASDKPGQDNSCYQQKI
uniprot
proteins
ec_number
1.1.1.51
uniprot
proteins
ec_number
1.1.1.62
uniprot
proteins
function
FUNCTION: Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed:9658408). Also has 20-alpha-HSD activity. Uses preferentially NADH (By similarity). {ECO:0000250|UniProtKB:P14061, ECO:0000269|PubMed:9658408}.
uniprot
proteins
mass_dalton
36785
uniprot
proteins
pathway_participation
PATHWAY: Steroid biosynthesis; estrogen biosynthesis. {ECO:0000269|PubMed:9658408}.
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
8612620
uniprot
proteins
pubmed
9658408
uniprot
proteins
sequence_length
344
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins