Tmem88
entrez
67020
canonical
uniprot
Q9D0N8
canonical
ensembl
ENSMUSG00000045377
resolver
ensp
ENSMUSP00000055528
resolver
enst
ENSMUST00000050140
resolver
genesymbol
Tmem88
resolver
uniprot
Q497Z2
resolver
uniprot
Q8BRC2
resolver
uniprot_entry
TMM88_MOUSE
resolver
uniprot_sec
Q497Z2
resolver
uniprot_sec
Q8BRC2
resolver
amino_acid_sequence
MAEVPGAQRPVLAGGPEPRDPLDCWACAVLVTAQNLLVAVFNLLLLALVLGTILLPAVIMLGFGFLCHSQFLRSQAPLCTSHLRDPGFTALLVTGFLLLVPLLVLALATYRRLCLRLRLADCLVPYSRALYRRRRIPQPKQIPVSPGSRSVPTPGKVWV
uniprot
proteins
function
FUNCTION: Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
17358
uniprot
proteins
protein_family
TMEM88 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
159
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins