EXTL1
entrez
2134
canonical
uniprot
Q92935
canonical
ensembl
ENSG00000158008
resolver
ensp
ENSP00000363398
resolver
ensp
ENSP00000552675
resolver
ensp
ENSP00000697369
resolver
enst
ENST00000374280
resolver
genesymbol
EXTL1
resolver
genesymbol_syn
EXTL
resolver
hgnc
HGNC:3515
resolver
uniprot
Q6GSC1
resolver
uniprot_entry
EXTL1_HUMAN
resolver
uniprot_sec
Q6GSC1
resolver
amino_acid_sequence
MQSWRRRKSLWLALSASWLLLVLLGGFSLLRLALPPRPRPGASQGWPRWLDAELLQSFSQPGELPEDAVSPPQAPHGGSCNWESCFDTSKCRGDGLKVFVYPAVGTISETHRRILASIEGSRFYTFSPAGACLLLLLSLDAQTGECSSMPLQWNRGRNHLVLRLHPAPCPRTFQLGQAMVAEASPTVDSFRPGFDVALPFLPEAHPLRGGAPGQLRQHSPQPGVALLALEEERGGWRTADTGSSACPWDGRCEQDPGPGQTQRQETLPNATFCLISGHRPEAASRFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALQEMSPARVLALRQQTQFLWDAYFSSVEKVIHTTLEVIQDRIFGTSAHPSLLWNSPPGALLALSTFSTSPQDFPFYYLQQGSRPEGRFSALIWVGPPGQPPLKLIQAVAGSQHCAQILVLWSNERPLPSRWPETAVPLTVIDGHRKVSDRFYPYSTIRTDAILSLDARSSLSTSEVDFAFLVWQSFPERMVGFLTSSHFWDEAHGGWGYTAERTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTLADEAPTCVDVLMNFIVAAVTKLPPIKVPYGKQRQEAAPLAPGGPGPRPKPPAPAPDCINQIAAAFGHMPLLSSRLRLDPVLFKDPVSVQRKKYRSLEKP
uniprot
proteins
ec_number
2.4.1.224
uniprot
proteins
function
FUNCTION: Glycosyltransferase required for the biosynthesis of heparan-sulfate (HS) (PubMed:11390981). Transfers N-acetyl-alpha-D-glucosamine to the nascent HS chain (GlcNAcT-II activity) (PubMed:11390981). Appears to lack GlcNAcT I and GlcAT-II activities (PubMed:11390981). {ECO:0000269|PubMed:11390981}.
uniprot
proteins
mass_dalton
74697
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000305|PubMed:11390981}.
uniprot
proteins
protein_family
Glycosyltransferase 47 family
uniprot
proteins
pubmed
10480354
uniprot
proteins
pubmed
10575224
uniprot
proteins
pubmed
11390981
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
9037597
uniprot
proteins
sequence_length
676
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 10..30; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins