COMMD10
entrez
51397
canonical
uniprot
Q9Y6G5
canonical
ensembl
ENSG00000145781
resolver
ensp
ENSP00000274458
resolver
ensp
ENSP00000427319
resolver
ensp
ENSP00000488332
resolver
enst
ENST00000274458
resolver
enst
ENST00000515539
resolver
enst
ENST00000632434
resolver
genesymbol
COMMD10
resolver
hgnc
HGNC:30201
resolver
uniprot
D3DT07
resolver
uniprot
D6RJ90
resolver
uniprot
Q9P077
resolver
uniprot_entry
COMDA_HUMAN
resolver
uniprot_entry
D6RJ90_HUMAN
resolver
uniprot_sec
D3DT07
resolver
uniprot_sec
Q9P077
resolver
amino_acid_sequence
MAVPAALILRESPSMKKAVSLINAIDTGRFPRLLTRILQKLHLKAESSFSEEEEEKLQAAFSLEKQDLHLVLETISFILEQAVYHNVKPAALQQQLENIHLRQDKAEAFVNTWSSMGQETVEKFRQRILAPCKLETVGWQLNLQMAHSAQAKLKSPQAVLQLGVNNEDSKSLEKVLVEFSHKELFDFYNKLETIQAQLDSLT
uniprot
proteins
function
FUNCTION: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:37172566, ECO:0000269|PubMed:38459129, ECO:0000305|PubMed:21778237}.
uniprot
proteins
mass_dalton
22966
uniprot
proteins
protein_family
COMM domain-containing protein 10 family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15799966
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21778237
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23563313
uniprot
proteins
pubmed
23637203
uniprot
proteins
pubmed
25355947
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
37172566
uniprot
proteins
pubmed
38459129
uniprot
proteins
pubmed
38504028
uniprot
proteins
sequence_length
202
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}.
uniprot
proteins