ANKRD16
entrez
54522
canonical
uniprot
Q6P6B7
canonical
ensembl
ENSG00000134461
resolver
ensp
ENSP00000352361
resolver
ensp
ENSP00000369434
resolver
ensp
ENSP00000369436
resolver
genesymbol
ANKRD16
resolver
hgnc
HGNC:23471
resolver
uniprot
A6NEF0
resolver
uniprot
F8WEI4
resolver
uniprot
Q9NT01
resolver
uniprot_entry
ANR16_HUMAN
resolver
uniprot_sec
A6NEF0
resolver
uniprot_sec
F8WEI4
resolver
uniprot_sec
Q9NT01
resolver
amino_acid_sequence
MAQPGDPRRLCRLVQEGRLRALKEELQAAGGCPGPAGDTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSGLKDSEDITGTLAQQLPRRADVLQGSGHSAMT
uniprot
proteins
function
FUNCTION: Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. {ECO:0000250|UniProtKB:A2AS55}.
uniprot
proteins
mass_dalton
39284
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19690332
uniprot
proteins
sequence_length
361
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:A2AS55}. Nucleus {ECO:0000250|UniProtKB:A2AS55}.
uniprot
proteins