Pum3
entrez
52874
canonical
uniprot
Q8BKS9
canonical
ensembl
ENSMUSG00000041360
resolver
ensp
ENSMUSP00000075573
resolver
ensp
ENSMUSP00000157590
resolver
ensp
ENSMUSP00000282789
resolver
enst
ENSMUST00000076219
resolver
enst
ENSMUST00000236702
resolver
genesymbol
Pum3
resolver
genesymbol_syn
D19Bwg1357e
resolver
genesymbol_syn
Kiaa0020
resolver
uniprot
A0A0N4SUH4
resolver
uniprot
Q6A0E6
resolver
uniprot
Q8BU15
resolver
uniprot_entry
A0A0N4SUH4_MOUSE
resolver
uniprot_entry
PUM3_MOUSE
resolver
uniprot_sec
Q6A0E6
resolver
uniprot_sec
Q8BU15
resolver
amino_acid_sequence
MEVKGKKKFTGKSPQTSQGKNKFHKNSESSSSKTFPRKAVKEGGPKVTSKNFEKGATKPGKKGVKQFKNKPQGGKGPKDKFQKANKFSKKRKFQPDGESDESGAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKHIWESLRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCFIQYGNEEQRKQAFQELQGDLVELSKAKYSRNIVKKFLMYGSKPQVAEIIRSFKGHVRKMLRHSEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADHPTLDKVLELQPAKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKPRSELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLMSPRDPAHTVPELIELLQKGDGNAHSKKDTAIRRRELLESISPALLSYLQGHTQEVVLDKSACVLVSDMLGSATGDVQPAMDAIASLAAAELHPGGKDGELHVAEHPAGHLVLKWLLEQDKKMKESGKEGCFAKTLVERVGMKNLKSWASINRGAIILSSLLQSCDQEVVNKVKGGLKPLIPTLEKNKSSSRGIQTLLEKLTA
uniprot
proteins
function
FUNCTION: Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells. {ECO:0000250|UniProtKB:Q15397, ECO:0000250|UniProtKB:X1WGX5}.
uniprot
proteins
mass_dalton
72800
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19319195
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
647
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q15397}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q15397}. Chromosome {ECO:0000250|UniProtKB:Q15397}. Note=Localizes predominantly in the nucleolus with minor punctate signals in the nucleoplasm. {ECO:0000250|UniProtKB:Q15397}.
uniprot
proteins