Cuzd1
entrez
16433
canonical
uniprot
P70412
canonical
ensembl
ENSMUSG00000040205
resolver
ensp
ENSMUSP00000037168
resolver
enst
ENSMUST00000046611
resolver
genesymbol
Cuzd1
resolver
genesymbol_syn
Itmap1
resolver
uniprot
B2RU69
resolver
uniprot
Q9CTZ7
resolver
uniprot_entry
CUZD1_MOUSE
resolver
uniprot_sec
B2RU69
resolver
uniprot_sec
Q9CTZ7
resolver
amino_acid_sequence
MEVTGRLFIWAILAVSCGAQLNSTEAEGKSRCTASLGGANLGETHKALVLQLSANENCTWTIERPENRSIRIIFSYIKLDPGSRCETENIKVFDGSSTSGPLLGKACSRNDFVPVFESSSNSMTFQIVTGLTKFPRSVFIFYYFFSAATVIPNCGGDLRALEGSFSSPNYPKPHPELAYCVWHIQVGKGYKIQLKFTDLLLEMDENCKFDFIAVYDGPSTTAGLLKQLCGRGKPTLESSSDAMTVVLSTDYANSYKGFSASYTSIYIHDVNTTSLSCVSDKMRVIISKSYLPALNYNESNLQLNDPTCRPNVSNVIEFSIPLHECGTVKKIEDHAISYTNRITFIESPVSAVITRQKLLQIVVTCEMEYNSTVEIMYITEDDIIQNQSVLGKYNTSLALYESDSFENLVQESPYYVDLNQTLFVQATLHTSDPSLVVFLDTCRASPTSDFASPTYDLISSGCCQDETCKVYPLFGHYGRFQFNAFKFLKHLNSVYLKCKILICDNNDQTSRCNQGCVPRRKRDIPSYKWKTDSVIGPIRLKRDRSASRDSGLLPQIHEAEISNQPLSRLYLFSFMVLALNVVIVAITTVKHFLNRWMDHRYQKLQVY
uniprot
proteins
function
FUNCTION: Localized to zymogen granules, where it functions in trypsinogen activation (PubMed:12401800). May indirectly regulate cell motility, cell-cell and cell/extracellular matrix interactions (By similarity). {ECO:0000250|UniProtKB:Q86UP6, ECO:0000269|PubMed:12401800}.
uniprot
proteins
mass_dalton
68195
uniprot
proteins
pubmed
12401800
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9480914
uniprot
proteins
sequence_length
607
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Zymogen granule membrane {ECO:0000269|PubMed:12401800}; Single-pass type I membrane protein {ECO:0000269|PubMed:12401800}.
uniprot
proteins
transmembrane_region
TRANSMEM 569..589; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins