Maged1
entrez
84469
canonical
uniprot
Q9ES73
canonical
ensembl
ENSRNOG00000006756
resolver
ensembl
ENSRNOG00065010147
resolver
ensp
ENSRNOP00000009870
resolver
ensp
ENSRNOP00065012413
resolver
enst
ENSRNOT00000009870
resolver
enst
ENSRNOT00065016356
resolver
genesymbol
Maged1
resolver
genesymbol_syn
Nrage
resolver
uniprot
Q66HP3
resolver
uniprot
Q9JHZ6
resolver
uniprot
Q9QX92
resolver
uniprot_entry
MAGD1_RAT
resolver
uniprot_sec
Q66HP3
resolver
uniprot_sec
Q9JHZ6
resolver
uniprot_sec
Q9QX92
resolver
amino_acid_sequence
MAQKPDGGAGLRGFQAEASVEDSALLVQTLMEAIQISEAPPTSQATAAASGPNASPQSSQPPTANEKADTEVSAAAARPKTGFKAQNTTTKGPNDYSQARNAKEMPKNQPKVAFKSQNATSKGPHAASDFSHAASTGKSAAKKSEMAFKGQNTTTKAGPSATYNFTQSPSANEMTNNQPKTAKAWNDTTKIPGADAQTQNVNQAKMADVGTSAGISETDGAAAQTSADGSQAQNVESRTIIRGKRTRKINNLNVEENSNGDQRRASLASGNWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGWQNQTARQTPPARQSPPARQTPSAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPIVWPNPMAWQSTPGWQSPPSWQAPPSWQSPQDWQGPPDWQLPPDWSMPPDWSFPSDWPFPPDWIPADWPIPPDWQNLRPSPNLRSSPNSRASQNQGPPQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGIIFMNGNRATEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARNRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQAFTGPIIGPSGTATANFAANFGAIGFFWVE
uniprot
proteins
function
FUNCTION: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as BMAL1 and NFIL3, induced, or NR1D1, repressed. {ECO:0000269|PubMed:10985348}.
uniprot
proteins
mass_dalton
85798
uniprot
proteins
pubmed
10985348
uniprot
proteins
pubmed
11014239
uniprot
proteins
pubmed
12598531
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
775
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus {ECO:0000250}. Note=Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF.
uniprot
proteins