Fbxw20
entrez
434440
canonical
uniprot
Q5U467
canonical
ensembl
ENSMUSG00000061701
resolver
ensp
ENSMUSP00000078503
resolver
enst
ENSMUST00000079548
resolver
genesymbol
Fbxw20
resolver
genesymbol_syn
BC085247
resolver
genesymbol_syn
Fbxw12
resolver
uniprot
L7MTZ5
resolver
uniprot_entry
L7MTZ5_MOUSE
resolver
uniprot_entry
Q5U467_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: In oocytes and preimplantation embryos, SCF(Fbxw20) ubiquitin ligase complex is maintained inactive by cytoplasmic lattices. {ECO:0000269|PubMed:41986725}.
uniprot
proteins
amino_acid_sequence
MEVHLPRLPLMKIFSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLFCDMVTLQLLGTETWKQFFVFRTWQEHAKTRAKPEDFTYKEIPAEYGFRANACYISGCGLTRNVQDRSVICMVSSMTKLSTWDIREGIMTWVSTEQPAYIKLLTTLPEMHIAVTVDTHSTIKLWDCHNREALATNCLFSSCKLLKAVFSKDDPIVLVGDISGNLYIFRIPDLHLISKVNVFPYGIDELHCSPQKKWVFLIMKHPRVLTKVVYMNSLLRTSEFSAPVSTILKFSLCDKAFWTPRREDRITQMSRGVPPRPTKFATFDMKLEEIGNKVTVQEYLVASFSLQDYEASPEWMGVSNKDVIVCSTGSSLLLFNIHGLRLQTFHYCPEEILRLWVDPLHVIVTCNDGSMDVYAWEERSLLLRKCYRLQNRRNLPPESFIFKTLCDDVSIIGVMTNSPAPCFLMAYTLASALEN
uniprot
proteins
function
FUNCTION: Substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, which mediates ubiquitination and degradation of target proteins. {ECO:0000250|UniProtKB:E9PXM9}.
uniprot
proteins
mass_dalton
53974
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:E9PXM9}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
41986725
uniprot
proteins
sequence_length
468
uniprot
proteins