Rpgrip1
entrez
77945
canonical
uniprot
Q9EPQ2
canonical
ensembl
ENSMUSG00000057132
resolver
ensp
ENSMUSP00000107227
resolver
ensp
ENSMUSP00000107230
resolver
ensp
ENSMUSP00000138027
resolver
enst
ENSMUST00000111600
resolver
genesymbol
Rpgrip1
resolver
uniprot
E9QQ97
resolver
uniprot
Q0VGR8
resolver
uniprot
Q8CAC2
resolver
uniprot
Q8CDJ9
resolver
uniprot
Q91WE0
resolver
uniprot
Q9CUK6
resolver
uniprot
Q9D5Q1
resolver
uniprot_entry
E9QQ97_MOUSE
resolver
uniprot_entry
Q0VGR8_MOUSE
resolver
uniprot_entry
RPGR1_MOUSE
resolver
uniprot_sec
Q8CAC2
resolver
uniprot_sec
Q8CDJ9
resolver
uniprot_sec
Q91WE0
resolver
uniprot_sec
Q9CUK6
resolver
uniprot_sec
Q9D5Q1
resolver
amino_acid_sequence
MQHLLEYMPEDLPVRDTDSSPLLKGTSGKNVRAQPHLGRMNQKELNCRRLHLHEEPTLVKEPSPKQRDKNRRRRTNVQRSTTTQPDLRTLAVLQEPERRRRPWVSASPSPSAPPRAPVPGRKAHVQRLCPSTAVGSAQPRVHAGRRLPHIAGPNDRRSHTAPPAFKDYVADKNTRIEITREPSQLTHTMTTDSTHVEEIPRSPEKTSKVEKPEQRSSEECTQKAAELRASIKENVELIRLKKLLQERNTSLAATEAQLTRVQEAYEDLLQKNQGILDTAHNAFLSQVNELKAELSEESKKAVSLRTQLGDVSILQITLKEFQVRVEDLEKERKLLSDSYDRLLENMLDSSHQPLDSSHQPHWSTELTGKQLPPQVCPLLDQMGTALEETKVFRQATNKAAQDGKLKFQDTDILYQHEQEEESLQSTATVASSPEELCELAAQPTLLPQTDQRESSEPKAQDENDLSQVLSELQVSHAETTLELEKTRDMLLLQRKINMCYQEELEATLTKADRENRDHEEKLERLNHLLDFKNSRIKQLEGILRSHGLPTSEQLKDVAYGTLPPSLCLEPLAAHRGDDEVDMSLLHPSENLFELHVHQAFLTPAALTQAGDTQPTTFCTYSFYDFETHCTPLSTGPQPLYDFTSQYVVQADYLLLHYLQGTSVRLDLHQAMASEYHVLATGWISLDKVLGTVERVHGLATLAGAGGEDLGVLEYWMRLCLPLKPSLQACNKRKKAQAYLSVSVLGARKVQSNESRSETWAPQNELRVEITRCCGLRSRRLGRQPSPYVMYRFFTFPDHDTIIIPASSNPYFKDQALFPVLVTSDLDQYLRREALSVYVFDDEDPEPGSYLGRAQVPLLPLAQNKSIKGDFNLTDSGEKSNGSIKVQLDWKSHYLAPEGFQMSEAEKPEGEEKEEEGGEEEVKEEEVEEEEEEEEEEEEVKEEKEEEEEEEREEEEEKEEEKEEEEEEDEKEEEEEEEEEEEEEEEDENKDVLEASFTEEWVPFFSQDQIASTEIPIEAGQYPEKRKPPVIAEKKEREHQVASYSRRKHSKKPGVQDKNRMEYLSCNILNGNTQQMHYTEWKFSGLKKAEDGGLKAQDKREEPPSPRSALRQEHPSHPRNAFSLADQESCEQASEVSETQTTDSDDIIVTPQAQTVPKADSEKMCIEIVSLAFCPEADVMSDETIQQVYVEYKFCDLPLSETETPMSLRKPRAGEEIHFHFSKVIDLDPVEHQSRRQFLFAMLHAQDSDEGRFKFTVVSDPLDEEKKECQDIGYAYLELWQIFQSGKDILEQELEIVSPRNQAIQIGRLKVSLQAAAALHGIYKEMTEDLFS
uniprot
proteins
function
FUNCTION: May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells. {ECO:0000269|PubMed:12651948}.
uniprot
proteins
mass_dalton
151996
uniprot
proteins
protein_family
RPGRIP1 family
uniprot
proteins
pubmed
11104772
uniprot
proteins
pubmed
12140192
uniprot
proteins
pubmed
12651948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
25398945
uniprot
proteins
pubmed
29100828
uniprot
proteins
pubmed
29899041
uniprot
proteins
sequence_length
1331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000269|PubMed:11104772, ECO:0000269|PubMed:12651948, ECO:0000269|PubMed:29100828}. Note=Situated between the axonemal microtubules and the plasma membrane (PubMed:11104772, PubMed:12651948). In the retinal photoreceptor cell layer, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (PubMed:29100828, PubMed:29899041). Colocalizes with RGPR in the photoreceptor connecting cilium (PubMed:11104772, PubMed:12140192, PubMed:12651948). {ECO:0000269|PubMed:11104772, ECO:0000269|PubMed:12140192, ECO:0000269|PubMed:12651948, ECO:0000269|PubMed:29100828, ECO:0000269|PubMed:29899041}.
uniprot
proteins