Pomt2
entrez
217734
canonical
uniprot
Q8BGQ4
canonical
ensembl
ENSMUSG00000034126
resolver
ensp
ENSMUSP00000035260
resolver
ensp
ENSMUSP00000330524
resolver
genesymbol
Pomt2
resolver
uniprot
Q8R4Z0
resolver
uniprot_entry
POMT2_MOUSE
resolver
uniprot_sec
Q8R4Z0
resolver
amino_acid_sequence
MLYASGRLLAARAATTLSAPPRARGPALRGKRRELQIPWHLETPSYDPLTGQRTRPGVPPARRVILRKGRMPPAIGGGLAGSELRPRRGRCVPQAARAVSRDVVPQAAARKLKRPAWSSRRFQAAGWWATLAVVTLLSFATRFHRLDQPAHICWDETHFGKMGSYYINRTFFFDVHPPLGKMLIGLAGYLSGYDGTFLFQKPGDRYEHHSYMGMRGFCAFLGSWLIPFAYLTVLDLSKSFPAALLTAALLTFDTGCLTLSQYILLDPILMFFIMAAMLSMVKYNSCANRPFSAPWWFWLSLTGISLAGALGVKFVGLFIIVQVGLNTISDLWHLFGDLSLSLVTVGKHLTARILCLIVLPLVLYVTIFAVHVMVLNKSGPGDGFFSSAFQARLSGNSLHNASIPEHLAYGSVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHKDYNNLWIIKKYNANTDPLDPSFPVEFVRHGDIIRLEHKETTRNLHSHYHEAPLTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFGNRIKVLRSRIRLIHLVTGCVLGSSGKILPKWGWEQLEVTCTPYLKETTNSIWNIEEHINPKLPNISLDVLQPSFPEILLESHMVMIRGNNGLKPKDNEFTSKPWHWPINYQGLRFSGANDTDFRVYLLGNPVVWWLNLVSIVLYLLSGSTIAVAMQRGIQLPAELQGLTKVLLRGGGQLLLGWMLHYFPFFLMGRILYFHHYFPAMLFSSMLTGILWDTLLRLCAWGLAPSPLGRRIHAVGILSLLLTTAYSFYLFHPLAYGMVGPLAQEPESPMAGLRWLESWDF
uniprot
proteins
ec_number
2.4.1.109
uniprot
proteins
function
FUNCTION: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. {ECO:0000250|UniProtKB:Q9UKY4}.
uniprot
proteins
mass_dalton
92386
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:12460945}.
uniprot
proteins
protein_family
Glycosyltransferase 39 family
uniprot
proteins
pubmed
12460945
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
820
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 124..144; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 170..190; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 216..236; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 301..321; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 353..373; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 659..679; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 713..733; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 735..755; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 774..794; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins