Hmgn1
entrez
15312
canonical
uniprot
P18608
canonical
ensembl
ENSMUSG00000040681
resolver
ensp
ENSMUSP00000061012
resolver
enst
ENSMUST00000050884
resolver
genesymbol
Hmgn1
resolver
genesymbol_syn
Hmg-14
resolver
genesymbol_syn
Hmg14
resolver
uniprot
Q5HZY9
resolver
uniprot
Q8CEW1
resolver
uniprot_entry
HMGN1_MOUSE
resolver
uniprot_entry
Q8CEW1_MOUSE
resolver
uniprot_sec
Q5HZY9
resolver
amino_acid_sequence
MPKRKVSADGAAKAEPKRRSARLSAKPAPAKVDAKPKKAAGKDKASDKKVQIKGKRGAKGKQADVADQQTTELPAENGETENQSPASEEEKEAKSD
uniprot
proteins
function
FUNCTION: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2. {ECO:0000269|PubMed:15327773}.
uniprot
proteins
mass_dalton
10152
uniprot
proteins
post_translational_modification
PTM: Phosphorylation favors cytoplasmic localization (By similarity). Phosphorylation on Ser-20 and Ser-24 weakens binding to nucleosomes and increases the rate of H3 phosphorylation. {ECO:0000250, ECO:0000269|PubMed:15327773, ECO:0000269|PubMed:7925294}.
uniprot
proteins
protein_family
HMGN family
uniprot
proteins
pubmed
15327773
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
2402471
uniprot
proteins
pubmed
3342876
uniprot
proteins
pubmed
7925294
uniprot
proteins
sequence_length
96
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}. Note=Cytoplasmic enrichment upon phosphorylation. {ECO:0000250}.
uniprot
proteins