Lmbrd2
entrez
320506
canonical
uniprot
Q8C561
canonical
ensembl
ENSMUSG00000039704
resolver
ensp
ENSMUSP00000087858
resolver
ensp
ENSMUSP00000154020
resolver
ensp
ENSMUSP00000252719
resolver
genesymbol
Lmbrd2
resolver
uniprot
Q3U5C1
resolver
uniprot
Q501M6
resolver
uniprot
Q8BQ06
resolver
uniprot_entry
LMBD2_MOUSE
resolver
uniprot_sec
Q3U5C1
resolver
uniprot_sec
Q501M6
resolver
uniprot_sec
Q8BQ06
resolver
amino_acid_sequence
MSGAALGLEIVFVFFLALFLLHRYGDFKKQHRLVIIGTLLAWYLCFLIVFILPLDVSTTIYNRCRHAAANSSPPENTNVTGLDASVTPAPRQHPCFKPWSYIPDGIMPIFWRVVYWTSQFLTWILLPFMQSYARSGGFSITGKIKTALIENAIYYGTYLLIFGAFLIYVAVNPRLHLEWNQLQTIGIAAANTWGLFLLVLLLGYGLVEIPRSYWNGAKRGYLLMKTYFKAAKLMTEKADAEENLEDVMEEVRKVNESIKYNHPLRKCVDTILKKCPTDYQEKMGRNMDDYEDFDEKRNTYPSEKSLVKLHKQVIYSVQRHRRTQVQWQILLEQAFYLEDVAKNETSATHQFVHTFQSPEPENRFIQYFYNPTVEWYWECLLRPWFHRTLAVVLSIFSVIVVWSECTFFSTTPVLSLFAVFIQLAERTYNYIYIEIACFLSIFFLSICVYSTVFRIRVFNYYYLASHHQTDAYSLLFSGMLFCRLTPPLCLNFLGLTHMDSSISHQNTQPTAYTSIMGSMKVLSFIADGFYIYYPMLVVILCIATYFSLGTRCLNLLGFQQFMGDNDMTSDLVDEGKELIRREKRKRQRQEEGENRRREWKERYGHNREDSTRNRNVHPDPKESNFSDTTTNWSSKYTRANNRTERDRIELLQDAEPLDFNAETFTDESLEPESGRYQPGGRYLSMSSSIIFEDI
uniprot
proteins
function
FUNCTION: Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G protein-coupled receptors including type-1 angiotensin II receptor/AGTR1. {ECO:0000250|UniProtKB:Q68DH5}.
uniprot
proteins
mass_dalton
81101
uniprot
proteins
protein_family
LIMR family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
694
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q68DH5}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 4..21; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 33..53; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 151..171; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 187..207; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 388..408; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 433..453; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 474..494; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 522..542; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins