TKTL2
entrez
84076
canonical
uniprot
Q9H0I9
canonical
ensembl
ENSG00000151005
resolver
ensp
ENSP00000280605
resolver
enst
ENST00000280605
resolver
genesymbol
TKTL2
resolver
hgnc
HGNC:25313
resolver
uniprot
A0A140VKC2
resolver
uniprot
A4FVB4
resolver
uniprot
Q8NCT0
resolver
uniprot
Q96M82
resolver
uniprot_entry
A0A140VKC2_HUMAN
resolver
uniprot_entry
TKTL2_HUMAN
resolver
uniprot_sec
A4FVB4
resolver
uniprot_sec
Q8NCT0
resolver
uniprot_sec
Q96M82
resolver
amino_acid_sequence
MMANDAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDPEHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVDVATGSLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPTAIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQISITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHPERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSELLDMFGISTRHIIAAVTLTLMK
uniprot
proteins
ec_number
2.2.1.1
uniprot
proteins
function
FUNCTION: Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. {ECO:0000269|PubMed:17321041}.
uniprot
proteins
mass_dalton
67877
uniprot
proteins
protein_family
Transketolase family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17321041
uniprot
proteins
sequence_length
626
uniprot
proteins