CALR3
entrez
125972
canonical
uniprot
Q96L12
canonical
ensembl
ENSG00000269058
resolver
ensp
ENSP00000269881
resolver
enst
ENST00000269881
resolver
genesymbol
CALR3
resolver
genesymbol_syn
CRT2
resolver
hgnc
HGNC:20407
resolver
uniprot
A0A140VJF7
resolver
uniprot
D9N574
resolver
uniprot
Q96LN3
resolver
uniprot_entry
A0A140VJF7_HUMAN
resolver
uniprot_entry
CALR3_HUMAN
resolver
uniprot_sec
D9N574
resolver
uniprot_sec
Q96LN3
resolver
amino_acid_sequence
MARALVQLWAICMLRVALATVYFQEEFLDGEHWRNRWLQSTNDSRFGHFRLSSGKFYGHKEKDKGLQTTQNGRFYAISARFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQKNLNGKSQYYIMFGPDICGFDIKKVHVILHFKNKYHENKKLIRCKVDGFTHLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWEKHFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGIHKDVWLHRKMKNTDYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPEREMDAIQAKEEMKKAREEEEEELLSGKINRHEHYFNQFHRRNEL
uniprot
proteins
function
FUNCTION: During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity). CALR3 capacity for calcium-binding may be absent or much lower than that of CALR. {ECO:0000250, ECO:0000269|PubMed:21590275}.
uniprot
proteins
mass_dalton
44996
uniprot
proteins
protein_family
Calreticulin family
uniprot
proteins
pubmed
12384296
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17655857
uniprot
proteins
pubmed
21590275
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
384
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:21590275}.
uniprot
proteins