Slain2
entrez
75991
canonical
uniprot
Q8CI08
canonical
ensembl
ENSMUSG00000036087
resolver
ensp
ENSMUSP00000115871
resolver
ensp
ENSMUSP00000116528
resolver
genesymbol
Slain2
resolver
genesymbol_syn
Kiaa1458
resolver
uniprot
Q05DK1
resolver
uniprot
Q3UJI9
resolver
uniprot
Q6ZPQ5
resolver
uniprot_entry
SLAI2_MOUSE
resolver
uniprot_sec
Q05DK1
resolver
uniprot_sec
Q3UJI9
resolver
uniprot_sec
Q6ZPQ5
resolver
amino_acid_sequence
MEDVNSNVNADQEVRKLQELVKKLEKQNEQLRSRSGAVQGAGLLGPGSPARVGVSTPSSGAASPRGFPLGLGAKASGGAGSGPRRTSSEDLRDATSLLAAGEGGLLDEVEPLRPDELERLSGWEEEEESWLYSSPKKKLTPMQKSVSPLVWCRQVLDYPSPDVECAKKSLIHKLDQTMSALKRQNLYNNPFNSVSYSNSYSPNASSPYSSGFNSPSSTPVRPPIVKQLILPGNSGNFKSSSDRNPPLSPQSSIDSELSASELDEDSIGSNYKLNDVTDVQILARMQEESLRQEYAASTSRRSSGSSCNSTRRGTFSDQELDAQSLDDEDDSLQHAVHPALNRFSPSPRNSPRPSPKQSPRNSPRSRSPARGIEYSRASPQPMISRLQQPRLSLQGHPTDLQTSNVKNEEKLRRSLPNLSRTSSTQVDSVKSSRSDSNFQVPNGGIPRMQPQASAIPSPGKFRSPAAPSPLALRQPVKAFSNHGSGSGSQETTQFTQTTSSPGPPVVQNSAPANPSSNINSATLTRPAGTTAMRSGLPRPSAPSAGGIPVPRSKLVQPVRRSLPAPKSYGSMKDDSWKDGCY
uniprot
proteins
function
FUNCTION: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. {ECO:0000269|PubMed:21646404}.
uniprot
proteins
mass_dalton
62378
uniprot
proteins
post_translational_modification
PTM: Is highly phosphorylated during mitosis, but not during interphase. The highly phosphorylated form does not localize at microtubule plus ends and does not interact with MAPRE1 or CKAP5 (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
SLAIN motif-containing family
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21646404
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
581
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules (By similarity). {ECO:0000250}.
uniprot
proteins