IRGC
entrez
56269
canonical
uniprot
Q6NXR0
canonical
ensembl
ENSG00000124449
resolver
ensp
ENSP00000244314
resolver
enst
ENST00000244314
resolver
genesymbol
IFGGE
resolver
genesymbol
IRGC
resolver
genesymbol_syn
IIGP5
resolver
genesymbol_syn
IRGC
resolver
genesymbol_syn
IRGC1
resolver
hgnc
HGNC:28835
resolver
uniprot
J7NNX4
resolver
uniprot
Q05BR8
resolver
uniprot_entry
IIGP5_HUMAN
resolver
uniprot_entry
J7NNX4_HUMAN
resolver
uniprot_sec
Q05BR8
resolver
amino_acid_sequence
MATSKLPVVPGEEENTILMAKERLEALRTAFESGDLPQAASHLQELLASTESIRLEVGVTGESGAGKSSLINALRGLEAEDPGAALTGVMETTMQPSPYPHPQFPDVTLWDLPGAGSPGCPADKYLKQVDFSRYDFFLLVSPRRCGAVETRLAAEILCQGKKFYFVRTKVDEDLAATRTQRPSGFREAAVLQEIRDHCAERLREAGVADPRIFLVSNLSPARYDFPTLVSTWEHDLPSHRRHAGLLSLPDISLEALQKKKAMLQEQVLKTALVLGVIQALPVPGLAAAYDDALLIHSLRGYHRSFGLDDDSLAKLAEQVGKQAGDLRSVIRSPLANEVSPETVLRLYSQSSDGAMRVARAFERGIPVFGTLVAGGISFGAVYTMLQGCLNEMAEDAQRVRIKALEDDEPQPEVSLEVASDNGVEKGGSGEGGGEEAPLSTCRKLGLLLKYILDSWKKHDSEEK
uniprot
proteins
ec_number
3.6.5.-
uniprot
proteins
function
FUNCTION: GTPase required for sperm motility and therefore male fertility, via positive regulation of spermatozoa fibrous sheath formation. {ECO:0000250|UniProtKB:Q8C262, ECO:0000250|UniProtKB:Q9QZ85}.
uniprot
proteins
mass_dalton
50288
uniprot
proteins
protein_family
IRG family
uniprot
proteins
protein_family
TRAFAC class dynamin-like GTPase superfamily
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
37195149
uniprot
proteins
sequence_length
463
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000269|PubMed:37195149}. Lipid droplet {ECO:0000269|PubMed:37195149}. Note=Expressed in the sperm mitochondrial sheath. {ECO:0000269|PubMed:37195149}.
uniprot
proteins