HGH1
entrez
51236
canonical
uniprot
Q9BTY7
canonical
ensembl
ENSG00000235173
resolver
ensp
ENSP00000321320
resolver
enst
ENST00000347708
resolver
genesymbol
C8orf30A
resolver
genesymbol
HGH1
resolver
genesymbol_syn
C8orf30A
resolver
genesymbol_syn
C8orf30B
resolver
genesymbol_syn
FAM203A
resolver
genesymbol_syn
FAM203B
resolver
hgnc
HGNC:24161
resolver
uniprot
P0CB43
resolver
uniprot
Q96BK8
resolver
uniprot_entry
HGH1_HUMAN
resolver
uniprot_entry
Q96BK8_HUMAN
resolver
uniprot_sec
P0CB43
resolver
amino_acid_sequence
MGEAGAGAGASGGPEASPEAEVVKLLPFLAPGARADLQAAAVRHVLALTGCGPGRALLAGQAALLQALMELAPASAPARDAARALVNLAADPGLHETLLAADPGLPARLMGRALDPQWPWAEEAAAALANLSREPAPCAALMAALAAAEPADSGLERLVRALCTPGYNARAPLHYLAPLLSNLSQRPAARAFLLDPDRCVVQRLLPLTQYPDSSVRRGGVVGTLRNCCFEHRHHEWLLGPEVDILPFLLLPLAGPEDFSEEEMERLPVDLQYLPPDKQREPDADIRKMLVEAIMLLTATAPGRQQVRDQGAYLILRELHSWEPEPDVRTACEKLIQVLIGDEPERGMENLLEVQVPEDVEQQLQQLDCREQEQLERELAPEPWVERATPT
uniprot
proteins
function
FUNCTION: Co-chaperone involved in the folding of nascent eukaryotic elongation factor eEF2, an essential component of the translation machinery. Recognizes a non-native conformation in the central domain of eEF2 and recruits the chaperonin-containing T-complex (TRiC) to the C-terminal region of the nascent polypeptide, preventing unproductive interactions and promoting efficient folding of the N-terminal GTPase domain. May also assist in eEF2 maturation by recruiting the molecular chaperone Hsp90. {ECO:0000250|UniProtKB:P48362}.
uniprot
proteins
mass_dalton
42129
uniprot
proteins
protein_family
HGH1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
390
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P48362}.
uniprot
proteins