Ppp1r11
entrez
294207
canonical
uniprot
Q6MFY6
canonical
ensembl
ENSRNOG00000082306
resolver
ensembl
ENSRNOG00055009082
resolver
ensembl
ENSRNOG00060003409
resolver
ensembl
ENSRNOG00065028577
resolver
ensp
ENSRNOP00000103917
resolver
genesymbol
Ppp1r11
resolver
uniprot
Q6AXZ8
resolver
uniprot_entry
PP1RB_RAT
resolver
uniprot_sec
Q6AXZ8
resolver
amino_acid_sequence
MAEAGAGGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCGHTHCVRGHRKGRRPTTPGPTPTTPPQPPDPSQPPPGPMQH
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. {ECO:0000250|UniProtKB:O60927}.
uniprot
proteins
mass_dalton
13936
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
post_translational_modification
PTM: Auto-ubiquitinated. {ECO:0000250|UniProtKB:O60927}.
uniprot
proteins
pubmed
15060004
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
127
uniprot
proteins