Cnot11
entrez
52846
canonical
uniprot
Q9CWN7
canonical
ensembl
ENSMUSG00000003135
resolver
ensp
ENSMUSP00000003219
resolver
ensp
ENSMUSP00000125638
resolver
enst
ENSMUST00000003219
resolver
enst
ENSMUST00000161515
resolver
genesymbol
Cnot11
resolver
genesymbol_syn
D1Bwg0212e
resolver
uniprot
Q3TJG9
resolver
uniprot_entry
CNO11_MOUSE
resolver
uniprot_sec
Q3TJG9
resolver
amino_acid_sequence
MPGGGASTASGRLLSSADPRGAREAAAFRSGPAGSSGGRGGAGGPGPGIGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSGFDSSVASRITESLVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPSETKISK
uniprot
proteins
function
FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Does not seem to be required for complex deadenylase function (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
54959
uniprot
proteins
protein_family
CNOT11 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
505
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins