TAS2R50
entrez
259296
canonical
uniprot
P59544
canonical
ensembl
ENSG00000212126
resolver
ensembl
ENSG00000273431
resolver
ensembl
ENSG00000276167
resolver
ensp
ENSP00000424040
resolver
ensp
ENSP00000458551
resolver
ensp
ENSP00000479785
resolver
enst
ENST00000506868
resolver
enst
ENST00000575654
resolver
enst
ENST00000613831
resolver
genesymbol
TAS2R50
resolver
hgnc
HGNC:18882
resolver
uniprot
P59545
resolver
uniprot
Q2M255
resolver
uniprot
Q645Y0
resolver
uniprot_entry
T2R50_HUMAN
resolver
uniprot_sec
P59545
resolver
uniprot_sec
Q2M255
resolver
uniprot_sec
Q645Y0
resolver
amino_acid_sequence
MITFLYIFFSILIMVLFVLGNFANGFIALVNFIDWVKRKKISSADQILTALAVSRIGLLWALLLNWYLTVLNPAFYSVELRITSYNAWVVTNHFSMWLAANLSIFYLLKIANFSNLLFLHLKRRVRSVILVILLGTLIFLVCHLLVANMDESMWAEEYEGNMTGKMKLRNTVHLSYLTVTTLWSFIPFTLSLISFLMLICSLCKHLKKMQLHGEGSQDLSTKVHIKALQTLISFLLLCAIFFLFLIVSVWSPRRLRNDPVVMVSKAVGNIYLAFDSFILIWRTKKLKHTFLLILCQIRC
uniprot
proteins
function
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
34558
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
11696554
uniprot
proteins
pubmed
12139982
uniprot
proteins
pubmed
12379855
uniprot
proteins
pubmed
12581520
uniprot
proteins
pubmed
12584440
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15496549
uniprot
proteins
pubmed
16541075
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 2..22; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 56..76; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 127..147; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 182..202; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 260..280; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins