Desi1
entrez
315160
canonical
uniprot
Q4KM30
canonical
ensembl
ENSRNOG00000005577
resolver
ensembl
ENSRNOG00055028759
resolver
ensembl
ENSRNOG00060031049
resolver
ensembl
ENSRNOG00065029894
resolver
ensp
ENSRNOP00000007424
resolver
ensp
ENSRNOP00055041015
resolver
ensp
ENSRNOP00060044721
resolver
ensp
ENSRNOP00065042531
resolver
enst
ENSRNOT00055049817
resolver
enst
ENSRNOT00060053920
resolver
enst
ENSRNOT00065051663
resolver
genesymbol
Desi1
resolver
genesymbol_syn
Fam152b
resolver
genesymbol_syn
Pppde2
resolver
uniprot_entry
DESI1_RAT
resolver
amino_acid_sequence
MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSSGISSCTPGGTLLGPPDSVVDVGNTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPFGQALRPFLDSIQIQPPGGNSVGRPNGQS
uniprot
proteins
ec_number
3.1.2.22
uniprot
proteins
ec_number
3.4.-.-
uniprot
proteins
function
FUNCTION: Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46 (By similarity). Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity). Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5) (By similarity). {ECO:0000250|UniProtKB:Q6ICB0, ECO:0000250|UniProtKB:Q9CQT7}.
uniprot
proteins
mass_dalton
18385
uniprot
proteins
protein_family
DeSI family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
168
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6ICB0}. Nucleus {ECO:0000250|UniProtKB:Q6ICB0}. Note=Shuttles between the nucleus and the cytoplasm; exported from the nucleus in a XPO1/CRM1-dependent manner via its nuclear export signal motifs. {ECO:0000250|UniProtKB:Q6ICB0}.
uniprot
proteins