PLEKHA2
entrez
59339
canonical
uniprot
Q9HB19
canonical
ensembl
ENSG00000169499
resolver
ensp
ENSP00000482228
resolver
ensp
ENSP00000482319
resolver
ensp
ENSP00000483078
resolver
ensp
ENSP00000573069
resolver
enst
ENST00000616927
resolver
enst
ENST00000617275
resolver
enst
ENST00000903010
resolver
genesymbol
PLEKHA2
resolver
genesymbol_syn
TAPP2
resolver
hgnc
HGNC:14336
resolver
uniprot
A0A087WZ32
resolver
uniprot
A8K727
resolver
uniprot_entry
A0A087WZ32_HUMAN
resolver
uniprot_entry
PKHA2_HUMAN
resolver
uniprot_sec
A8K727
resolver
amino_acid_sequence
MPYVDRQNRICGFLDIEEHENSGKFLRRYFILDTQANCLLWYMDNPQNLAMGAGAVGALQLTYISKVSIATPKQKPKTPFCFVINALSQRYFLQANDQKDMKDWVEALNQASKITVPKGGGLPMTTEVLKSLAAPPALEKKPQVAYKTEIIGGVVVHTPISQNGGDGQEGSEPGSHTILRRSQSYIPTSGCRASTGPPLIKSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLRTIFLKDVLKTHECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAVQALKCHPRETSFSRSISLTRPGSSSLSSGPNSILCRGRPPLEEKKALCKAPSVASSWQPWTPVPQAGEKLLPPGDTSEDSLFTPRPGEGSAPGVLPSSRIRHRSEPQHPKEKPFMFNLDDENIRTSDV
uniprot
proteins
function
FUNCTION: Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
47245
uniprot
proteins
pubmed
11001876
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25218447
uniprot
proteins
sequence_length
425
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. {ECO:0000250}.
uniprot
proteins