Ifne
entrez
230405
canonical
uniprot
Q80ZF2
canonical
ensembl
ENSMUSG00000045364
resolver
ensp
ENSMUSP00000059199
resolver
enst
ENSMUST00000056014
resolver
genesymbol
Ifne
resolver
genesymbol_syn
Ifne1
resolver
genesymbol_syn
Ifnt1
resolver
uniprot_entry
IFNE_MOUSE
resolver
amino_acid_sequence
MVHRQLPETVLLLLVSSTIFSLEPKRIPFQLWMNRESLQLLKPLPSSSVQQCLAHRKNFLLPQQPVSPHQYQEGQVLAVVHEILQQIFTLLQTHGTMGIWEENHIEKVLAALHRQLEYVESLGGLNAAQKSGGSSAQNLRLQIKAYFRRIHDYLENQRYSSCAWIIVQTEIHRCMFFVFRFTTWLSRQDPDP
uniprot
proteins
function
FUNCTION: Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral, including HSV-2, and bacterial, including Chlamydia muridarum, genital infections. {ECO:0000269|PubMed:23449591}.
uniprot
proteins
mass_dalton
22372
uniprot
proteins
protein_family
Type-I (or alpha/beta) interferon family
uniprot
proteins
pubmed
15233997
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
23449591
uniprot
proteins
sequence_length
192
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins