Tmed5
entrez
289883
canonical
uniprot
Q6AXN3
canonical
genesymbol
Tmed5
resolver
uniprot_entry
TMED5_RAT
resolver
amino_acid_sequence
MGVRMWLPFPMLLLSALPATLLSGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDGGELDIDFHLASPEGRTLVFEQRKSDGVHTVETEDGDYMFCFDNTFSTISEKVIFFELILDNMGEEVEGQEDWKKYITNTDVLEMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSVVNLMVMVVVSAIQVYTLKSLFEDKRKSRT
uniprot
proteins
function
FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
26136
uniprot
proteins
protein_family
EMP24/GP25L family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
229
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Probably cycles between compartments of the early secretatory pathway. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 197..217; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins