CRYZL1
entrez
9946
canonical
uniprot
O95825
canonical
ensembl
ENSG00000205758
resolver
ensp
ENSP00000370966
resolver
genesymbol
CRYZL1
resolver
genesymbol_syn
4P11
resolver
genesymbol_syn
FERRY4
resolver
hgnc
HGNC:2420
resolver
uniprot
B2RDX1
resolver
uniprot
B3KQ77
resolver
uniprot
Q96DY0
resolver
uniprot
Q9NVY7
resolver
uniprot_entry
QORL1_HUMAN
resolver
uniprot_sec
B2RDX1
resolver
uniprot_sec
B3KQ77
resolver
uniprot_sec
Q96DY0
resolver
uniprot_sec
Q9NVY7
resolver
amino_acid_sequence
MKGLYFQQSSTDEEITFVFQEKEDLPVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFPVGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKVHVAESCLEETGGLGVDIVLDAGVRLYSKDDEPAVKLQLLPHKHDIITLLGVGGHWVTTEENLQLDPPDSHCLFLKGATLAFLNDEVWNLSNVQQGKYLCILKDVMEKLSTGVFRPQLDEPIPLYEAKVSMEAVQKNQGRKKQVVQF
uniprot
proteins
function
FUNCTION: Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary) (PubMed:37267905, PubMed:37267906). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (PubMed:37267905). {ECO:0000269|PubMed:37267905, ECO:0000269|PubMed:37267906}.
uniprot
proteins
mass_dalton
38697
uniprot
proteins
protein_family
Quinone oxidoreductase subfamily
uniprot
proteins
protein_family
Zinc-containing alcohol dehydrogenase family
uniprot
proteins
pubmed
10191096
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
37267905
uniprot
proteins
pubmed
37267906
uniprot
proteins
sequence_length
349
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Early endosome {ECO:0000269|PubMed:37267905}.
uniprot
proteins