Chst8
entrez
68947
canonical
uniprot
Q8BQ86
canonical
ensembl
ENSMUSG00000060402
resolver
ensp
ENSMUSP00000077752
resolver
ensp
ENSMUSP00000145646
resolver
ensp
ENSMUSP00000159050
resolver
enst
ENSMUST00000078686
resolver
enst
ENSMUST00000205259
resolver
enst
ENSMUST00000238947
resolver
genesymbol
Chst8
resolver
uniprot
Q76EC6
resolver
uniprot
Q80XD4
resolver
uniprot_entry
CHST8_MOUSE
resolver
uniprot_sec
Q76EC6
resolver
uniprot_sec
Q80XD4
resolver
amino_acid_sequence
MTPRLGTMRLACMFSSILLFGAAGLLLFISLQDPIELSPQQVPGIKFSIRPQQPQHDSHLRISTEKGTRDSPSGSPRGLQLQAPDQPRPHPKAAGSPLRLRQRRRRLLIKKMPAAGTNQGNNSSETFIQPRPRTMDSRWVSLHQTQQERKRVMREACAKYRASSSRRAVTPRHVSRIFVEDRHRVLYCEVPKAGCSNWKRVLMVLAGLASSTADIQHNTVHYGSALKRLDTFDRQGIVHRLSTYTKMLFVREPFERLVSAFRDKFEHPNSYYHPVFGKAILARYRANASREALRTGSGVQFPEFVQYLLDVHRPVGMDIHWDHVSRLCSPCLIDYDFVGKFESMEDDANFFLRLIHAPGNLTFPRFKDRHSEEARTTSRITHQYFAQLSSLQRQRTYDFYYMDYLMFNYSKPFSDLY
uniprot
proteins
ec_number
2.8.2.-
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans (By similarity). Transfers sulfate to the 4-position of GalNAc in the context of GalNAcbeta1->4GlcNAcbeta1->R attached to both N-linked and core 2 branched O-linked oligosaccharides (By similarity). Required for biosynthesis of glycoprotein hormones such as LH, by mediating sulfation of their carbohydrate structure (PubMed:18431515). Not active toward chondroitin (By similarity). {ECO:0000250|UniProtKB:Q9H2A9, ECO:0000269|PubMed:18431515}.
uniprot
proteins
mass_dalton
48282
uniprot
proteins
protein_family
Sulfotransferase 2 family
uniprot
proteins
pubmed
12944377
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18431515
uniprot
proteins
sequence_length
417
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins