TP53INP2
entrez
58476
canonical
uniprot
Q8IXH6
canonical
ensembl
ENSG00000078804
resolver
ensp
ENSP00000363942
resolver
ensp
ENSP00000363943
resolver
ensp
ENSP00000564641
resolver
ensp
ENSP00000564642
resolver
ensp
ENSP00000564643
resolver
ensp
ENSP00000564644
resolver
ensp
ENSP00000564645
resolver
ensp
ENSP00000564647
resolver
ensp
ENSP00000564648
resolver
ensp
ENSP00000564649
resolver
ensp
ENSP00000564650
resolver
ensp
ENSP00000564651
resolver
ensp
ENSP00000564652
resolver
ensp
ENSP00000564653
resolver
ensp
ENSP00000564654
resolver
ensp
ENSP00000564655
resolver
ensp
ENSP00000564656
resolver
ensp
ENSP00000564657
resolver
ensp
ENSP00000632492
resolver
enst
ENST00000374809
resolver
enst
ENST00000374810
resolver
enst
ENST00000894582
resolver
enst
ENST00000894583
resolver
enst
ENST00000894584
resolver
enst
ENST00000894585
resolver
enst
ENST00000894586
resolver
enst
ENST00000894588
resolver
enst
ENST00000894589
resolver
enst
ENST00000894590
resolver
enst
ENST00000894591
resolver
enst
ENST00000894592
resolver
enst
ENST00000894593
resolver
enst
ENST00000894594
resolver
enst
ENST00000894595
resolver
enst
ENST00000894596
resolver
enst
ENST00000894597
resolver
enst
ENST00000894598
resolver
enst
ENST00000962433
resolver
genesymbol
TP53INP2
resolver
genesymbol_syn
C20orf110
resolver
genesymbol_syn
DOR
resolver
genesymbol_syn
PINH
resolver
hgnc
HGNC:16104
resolver
uniprot
A8K8S8
resolver
uniprot
E1P5P6
resolver
uniprot
Q5JX64
resolver
uniprot
Q8IYL5
resolver
uniprot
Q9NU00
resolver
uniprot_entry
T53I2_HUMAN
resolver
uniprot_sec
A8K8S8
resolver
uniprot_sec
E1P5P6
resolver
uniprot_sec
Q5JX64
resolver
uniprot_sec
Q8IYL5
resolver
uniprot_sec
Q9NU00
resolver
amino_acid_sequence
MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY
uniprot
proteins
function
FUNCTION: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. {ECO:0000269|PubMed:18030323, ECO:0000269|PubMed:19056683, ECO:0000269|PubMed:22470510}.
uniprot
proteins
mass_dalton
23980
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18030323
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19056683
uniprot
proteins
pubmed
19145107
uniprot
proteins
pubmed
22470510
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
220
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.
uniprot
proteins