Hgh1
entrez
59053
canonical
uniprot
Q8C3I8
canonical
ensembl
ENSMUSG00000022554
resolver
ensp
ENSMUSP00000023213
resolver
ensp
ENSMUSP00000258166
resolver
enst
ENSMUST00000023213
resolver
genesymbol
Hgh1
resolver
genesymbol_syn
Brp16
resolver
genesymbol_syn
Fam203a
resolver
uniprot
Q9JJF4
resolver
uniprot_entry
HGH1_MOUSE
resolver
uniprot_sec
Q9JJF4
resolver
amino_acid_sequence
MRGPGVGSGFSGERGLLEQEAGADTEAVELLPFLVLGARADLQAAAAQHVLALTGAGSGRTLLAGQPELLRALVDLAVAPAPAPSRDASRALVNLAADPNVHWQLLAADPELPARLLRCVLDPQWPWAEEAAAVLANLSREPAPCAALMEKLMAAEPERLGLERLVNALCTPSYNAAAPLHYLGPLLSNLSQQAEVRAFLLDPDRCVVQRLLPLTQYTDSSVRRGGVVGTLRNCCFEHRHHKWLLGAQVDILPFLLLPLAGPEEFSEEEMDQLPVDLQYLSPDKQREPDADIRKMLIEAVMLLTATAPGRKQVRDQGAYLILRELHSWEPEPDVRMACEKLIQVLIGDEPEAGMENLLEVQVPEDVEQQLQELDQQEQQELAQELRGNGAPHT
uniprot
proteins
function
FUNCTION: Co-chaperone involved in the folding of nascent eukaryotic elongation factor eEF2, an essential component of the translation machinery. Recognizes a non-native conformation in the central domain of eEF2 and recruits the chaperonin-containing T-complex (TRiC) to the C-terminal region of the nascent polypeptide, preventing unproductive interactions and promoting efficient folding of the N-terminal GTPase domain. May also assist in eEF2 maturation by recruiting the molecular chaperone Hsp90. {ECO:0000250|UniProtKB:P48362}.
uniprot
proteins
mass_dalton
42916
uniprot
proteins
protein_family
HGH1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
393
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P48362}.
uniprot
proteins