TESK2
entrez
10420
canonical
uniprot
Q96S53
canonical
ensembl
ENSG00000070759
resolver
ensp
ENSP00000361158
resolver
genesymbol
TESK2
resolver
hgnc
HGNC:11732
resolver
uniprot
B4DFN2
resolver
uniprot
Q5T422
resolver
uniprot
Q5T423
resolver
uniprot
Q8N520
resolver
uniprot
Q9Y3Q6
resolver
uniprot_entry
B4DFN2_HUMAN
resolver
uniprot_entry
TESK2_HUMAN
resolver
uniprot_sec
Q5T422
resolver
uniprot_sec
Q5T423
resolver
uniprot_sec
Q8N520
resolver
uniprot_sec
Q9Y3Q6
resolver
activity_regulation
ACTIVITY REGULATION: Activated by autophosphorylation on Ser-219. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFTCEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPSKSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSDGPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
uniprot
proteins
ec_number
2.7.12.1
uniprot
proteins
function
FUNCTION: Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
uniprot
proteins
mass_dalton
63639
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
TKL Ser/Thr protein kinase family
uniprot
proteins
pubmed
10512679
uniprot
proteins
pubmed
11418599
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
571
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11418599}.
uniprot
proteins