Tti2
entrez
234138
canonical
uniprot
Q8BGV4
canonical
ensembl
ENSMUSG00000031577
resolver
ensp
ENSMUSP00000096441
resolver
ensp
ENSMUSP00000147846
resolver
ensp
ENSMUSP00000147956
resolver
ensp
ENSMUSP00000148056
resolver
enst
ENSMUST00000098842
resolver
enst
ENSMUST00000209851
resolver
enst
ENSMUST00000209986
resolver
enst
ENSMUST00000210129
resolver
genesymbol
Tti2
resolver
genesymbol_syn
BC019943
resolver
genesymbol_syn
Rbm13
resolver
uniprot
A0A1B0GSJ1
resolver
uniprot
Q3UTH3
resolver
uniprot
Q8BNA7
resolver
uniprot
Q8VE31
resolver
uniprot_entry
A0A1B0GSJ1_MOUSE
resolver
uniprot_entry
Q8BNA7_MOUSE
resolver
uniprot_entry
TTI2_MOUSE
resolver
uniprot_sec
Q3UTH3
resolver
uniprot_sec
Q8VE31
resolver
amino_acid_sequence
MKLDSAEEKSGVGCSLPAEGSPPALEPAFSKILNRLSRPKSSGQGGARNAALKDLGALIEAAEGDRFFEGSGSGGSLRGMPEILGQVVRALEKFAAPEEKADGVEEHPEVPEKATEVGSLFLKLLGKVEAAKSSPDCPAWKTGLRHMSGPVYIFAITHRLKQPWTSPASQHVAGEVLSLLLRVTECSSVAGFLCGENEDDRGRFAVVLGLLKPHLNKETWKKNPAVKHVFSWTLQQVTQPWLNQHLEKILPPSLLISDDYQTENKILGVQCLHHIVVTVPAADLLQYNRAQVLYHALFNHLYMPEHHLIQAVLLCLLDLFPVLEKALHWKGDTARVTTHCHEVLQLILTHMEPEHRLLLRRTYARHLPAFVKRLGILTVRHLKRLEQVILGYLEVYDEPEDETRLKILETLKLVMQYTWPRIPCRVVVLLKALLKLICDISRDTIPTTEAAKSTMLQEATDCLILLDHCSQGQVKGLLAKIAVSCEDSTVVSCIRKVQQGSADSPGDDTEGD
uniprot
proteins
function
FUNCTION: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
56702
uniprot
proteins
protein_family
TTI2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
512
uniprot
proteins