LTO1
entrez
220064
canonical
uniprot
Q8WV07
canonical
ensembl
ENSG00000149716
resolver
ensp
ENSP00000279147
resolver
ensp
ENSP00000446129
resolver
enst
ENST00000279147
resolver
enst
ENST00000535657
resolver
genesymbol
LTO1
resolver
genesymbol_syn
ORAOV1
resolver
genesymbol_syn
TAOS1
resolver
hgnc
HGNC:17589
resolver
uniprot
B2R4R2
resolver
uniprot
Q8NFK0
resolver
uniprot_entry
LTO1_HUMAN
resolver
uniprot_sec
B2R4R2
resolver
uniprot_sec
Q8NFK0
resolver
amino_acid_sequence
MAGSQDIFDAIVMADERFHGEGYREGYEEGSSLGVMEGRQHGTLHGAKIGSEIGCYQGFAFAWKCLLHSCTTEKDSRKMKVLESLIGMIQKFPYDDPTYDKLHEDLDKIRGKFKQFCSLLNVQPDFKISAEGSGLSF
uniprot
proteins
function
FUNCTION: The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery (PubMed:26182403). May be required for biogenesis of the large ribosomal subunit and initiation of translation (PubMed:23318452). May play a role in the regulation of proline metabolism and ROS production (PubMed:24930674). {ECO:0000269|PubMed:23318452, ECO:0000269|PubMed:24930674, ECO:0000269|PubMed:26182403}.
uniprot
proteins
mass_dalton
15354
uniprot
proteins
protein_family
LTO1 family
uniprot
proteins
pubmed
12172009
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23318452
uniprot
proteins
pubmed
24930674
uniprot
proteins
pubmed
26182403
uniprot
proteins
sequence_length
137
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P53846}.
uniprot
proteins