LIAT1
entrez
400566
canonical
uniprot
Q6ZQX7
canonical
ensembl
ENSG00000187624
resolver
ensembl
ENSG00000283985
resolver
ensp
ENSP00000353245
resolver
genesymbol
LIAT1
resolver
genesymbol_syn
C17orf97
resolver
hgnc
HGNC:33800
resolver
uniprot
A0A0H4IV28
resolver
uniprot
A5D8T6
resolver
uniprot
Q6NSI2
resolver
uniprot
Q6PFW9
resolver
uniprot_entry
A0A0H4IV28_HUMAN
resolver
uniprot_entry
LIAT1_HUMAN
resolver
uniprot_sec
A5D8T6
resolver
uniprot_sec
Q6NSI2
resolver
uniprot_sec
Q6PFW9
resolver
amino_acid_sequence
METRGPGLAVRAESRRLVGIGPRAPPGRVGLQPSGRLDRRGGAGTMGYKDNDGEEEEREGGAAGPRGSRLPPITGGASELAKRKVKKKKRKKKTKGSGKGDDKHQSQSLKSQPLSSSFHDILSPCKERGPKPEHRQSKVEKKHLPSDSSTVSLPDFAEIENLANRINESLRWDGILADPEAEKERIRIYKLNRRKRYRCLALKGFHPDPEALKGFHPDPDALKGFHPDPEALKGFHPDPEALKGFHPDPEALKGFHPDPEALKGIHPDPEALKGIHPDPEALKGFHPDPEALKGFHPDPEALKGFHTDPEALKGFHIDPEALKGFHPDPKALKGFHPDPKALKGFHTDPEALKGFHPDPKALKGFHPDPEALKGFHPDPEALKGFHPDPEALKGFHTDPNAEEAPENLPYLSDKDGSSSHRQPTSKAECPNLCFEGNLTPKLLHSDLAPTLLE
uniprot
proteins
function
FUNCTION: Participates in nucleolar liquid-liquid phase separation (LLPS) through its N-terminal intrinsically disordered region (IDR). May be involved in ATE1-mediated N-terminal arginylation. {ECO:0000250|UniProtKB:Q810M6}.
uniprot
proteins
mass_dalton
49656
uniprot
proteins
post_translational_modification
PTM: Post-translationally modified by JMJD6 lysyl-hydroxylase activity at its Lys-rich domain, which inhibits its self-association and nucleolar localization. {ECO:0000250|UniProtKB:Q810M6}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
25369936
uniprot
proteins
pubmed
33443146
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:33443146}. Cytoplasm {ECO:0000269|PubMed:33443146}. Note=Shuttles between the cytoplasm and nucleoplasm, a significant portion localizes to the nucleolus. {ECO:0000269|PubMed:33443146}.
uniprot
proteins