Ctsz
entrez
64138
canonical
uniprot
Q9WUU7
canonical
ensembl
ENSMUSG00000016256
resolver
ensp
ENSMUSP00000016400
resolver
enst
ENSMUST00000016400
resolver
genesymbol
Ctsz
resolver
uniprot
Q545I6
resolver
uniprot_entry
CATZ_MOUSE
resolver
uniprot_entry
Q545I6_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: The disulfide bridge formed between Cys-35 in the propeptide and the active site residue Cys-94 may prevent activation of the zymogen through formation of a reversible covalent bond with the active site residue. {ECO:0000250|UniProtKB:Q9UBR2}.
uniprot
proteins
amino_acid_sequence
MASSGSVQQLPLVLLMLLLASAARARLYFRSGQTCYHPIRGDQLALLGRRTYPRPHEYLSPADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWPSILLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQDCDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATEMMSNYTGGIYAEHQDQAVINHIISVAGWGVSNDGIEYWIVRNSWGEPWGEKGWMRIVTSTYKGGTGDSYNLAIESACTFGDPIV
uniprot
proteins
ec_number
3.4.18.1
uniprot
proteins
function
FUNCTION: Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity). {ECO:0000250|UniProtKB:Q9R1T3, ECO:0000250|UniProtKB:Q9UBR2}.
uniprot
proteins
mass_dalton
33996
uniprot
proteins
protein_family
Peptidase C1 family
uniprot
proteins
pubmed
10760573
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
306
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome.
uniprot
proteins