Kcnab3
entrez
58981
canonical
uniprot
Q63494
canonical
ensembl
ENSRNOG00000008480
resolver
ensembl
ENSRNOG00055032773
resolver
ensembl
ENSRNOG00060019763
resolver
ensembl
ENSRNOG00065026266
resolver
ensp
ENSRNOP00000011523
resolver
ensp
ENSRNOP00000103130
resolver
ensp
ENSRNOP00055046769
resolver
ensp
ENSRNOP00060027960
resolver
ensp
ENSRNOP00065037187
resolver
enst
ENSRNOT00000011523
resolver
enst
ENSRNOT00000122661
resolver
enst
ENSRNOT00055056663
resolver
enst
ENSRNOT00060034120
resolver
enst
ENSRNOT00065045351
resolver
genesymbol
Kcnab3
resolver
genesymbol_syn
Ckbeta3
resolver
uniprot
A0ABK0LD03
resolver
uniprot
Q2KML7
resolver
uniprot_entry
A0ABK0LD03_RAT
resolver
uniprot_entry
KCAB3_RAT
resolver
uniprot_sec
Q2KML7
resolver
amino_acid_sequence
MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPVGGGHGNPPGGGGLGSKSRTAVVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDLLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLQGSLDRLQLEYVDIVFANRSDPSSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACSLITSKYDGQVPDACKATVKGYQWLKEKVQSEDGKKQQARVTDLLPIAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLGQLTPQTVMEIDALLGNKSHSKK
uniprot
proteins
ec_number
1.1.1.-
uniprot
proteins
function
FUNCTION: Regulatory subunit of the voltage-gated potassium (Kv) channels composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits (PubMed:8549760). The beta-3/KCNAB3 subunit may mediate closure of potassium channels (By similarity). Inactivates Kv1.4/KCNA4 alpha subunit-containing Kv channel current but not Kv1.1/KCNA1 or Kv1.5/KCNA5 channels (PubMed:8549760). May display nicotinamide adenine dinucleotide phosphate (NADPH)-dependent aldoketoreductase activity (By similarity). The binding of oxidized and reduced NADP(H) cofactors may be required for the regulation of potassium channel activity (By similarity). {ECO:0000250|UniProtKB:P63144, ECO:0000269|PubMed:8549760}.
uniprot
proteins
mass_dalton
43690
uniprot
proteins
protein_family
Shaker potassium channel beta subunit family
uniprot
proteins
pubmed
8549760
uniprot
proteins
sequence_length
404
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q14722}.
uniprot
proteins