Rab9b
entrez
319642
canonical
uniprot
Q8BHH2
canonical
ensembl
ENSMUSG00000043463
resolver
ensp
ENSMUSP00000049739
resolver
enst
ENSMUST00000058814
resolver
genesymbol
Rab9b
resolver
genesymbol_syn
Rab9B
resolver
uniprot
Q3KNA5
resolver
uniprot_entry
Q3KNA5_MOUSE
resolver
uniprot_entry
RAB9B_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. Regulated by GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity. Inhibited by GDP dissociation inhibitors (GDIs). {ECO:0000305}.
uniprot
proteins
amino_acid_sequence
MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPDHFPFVVLGNKVDKEDRQVTTEEAQAWCMENGNYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTIDLNSGSKASSSCC
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB9B is involved in the transport of proteins between the endosomes and the trans Golgi network (By similarity). May use NDE1/NDEL1 as an effector to interact with the dynein motor complex in order to control retrograde trafficking of RAB9-associated late endosomes to the TGN (By similarity). {ECO:0000250|UniProtKB:P51151, ECO:0000250|UniProtKB:P62820, ECO:0000250|UniProtKB:Q9NP90}.
uniprot
proteins
mass_dalton
22704
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25220469
uniprot
proteins
sequence_length
201
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or Mycobacterium. {ECO:0000250}.
uniprot
proteins