Pfkp
entrez
56421
canonical
uniprot
Q9WUA3
canonical
ensembl
ENSMUSG00000021196
resolver
ensp
ENSMUSP00000021614
resolver
ensp
ENSMUSP00000117030
resolver
ensp
ENSMUSP00000236263
resolver
enst
ENSMUST00000021614
resolver
genesymbol
Pfkp
resolver
genesymbol_syn
Pfkc
resolver
uniprot
F8WGW9
resolver
uniprot
Q3TNA9
resolver
uniprot
Q3U4P1
resolver
uniprot
Q3U7G4
resolver
uniprot
Q4KUG1
resolver
uniprot
Q543K8
resolver
uniprot
Q8C5I6
resolver
uniprot
Q8C605
resolver
uniprot
Q9JI86
resolver
uniprot_entry
F8WGW9_MOUSE
resolver
uniprot_entry
PFKAP_MOUSE
resolver
uniprot_entry
Q8C605_MOUSE
resolver
uniprot_sec
Q3TNA9
resolver
uniprot_sec
Q3U4P1
resolver
uniprot_sec
Q3U7G4
resolver
uniprot_sec
Q4KUG1
resolver
uniprot_sec
Q543K8
resolver
uniprot_sec
Q8C5I6
resolver
uniprot_sec
Q9JI86
resolver
activity_regulation
ACTIVITY REGULATION: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate. {ECO:0000255|HAMAP-Rule:MF_03184}.
uniprot
proteins
amino_acid_sequence
MSDLDSSSSSAYPKYLEHLSGDGKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWDCVSSILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENMCLKLSENRARKKRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLRGRRFEGNLNTYKRLAIKLPDEKIVKSNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHKMFAIYDGFEGFANGQIKEIGWADVGGWTGQGGSILGTKRTLPGKYLEKIAEQMHSHSINALLIIGGFEAYLGLLELAAAREKHEAFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALAAGADAAYIFEEPFDIGDLQSNVVHLTEKMKTSIQRGLVLRNESCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMEWISAKLKGSQGTGKKFVSDDSICVLGICKRDLLFQPVAELKKVTDFEHRIPKEQWWLKLRPIMKILAKYEASYDMSDSGKLESLQHHEEL
uniprot
proteins
ec_number
2.7.1.11
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
uniprot
proteins
mass_dalton
85455
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. {ECO:0000255|HAMAP-Rule:MF_03184}.
uniprot
proteins
post_translational_modification
PTM: GlcNAcylation decreases enzyme activity. {ECO:0000250}.
uniprot
proteins
protein_family
ATP-dependent PFK group I subfamily
uniprot
proteins
protein_family
Eukaryotic two domain clade 'E' sub-subfamily
uniprot
proteins
protein_family
Phosphofructokinase type A (PFKA) family
uniprot
proteins
pubmed
10814514
uniprot
proteins
pubmed
11137296
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15919810
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17947660
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
784
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}.
uniprot
proteins