Ticrr
entrez
77011
canonical
uniprot
Q8BQ33
canonical
ensembl
ENSMUSG00000046591
resolver
ensp
ENSMUSP00000041377
resolver
enst
ENSMUST00000035977
resolver
genesymbol
Ticrr
resolver
uniprot
B2RY55
resolver
uniprot
Q8C9N4
resolver
uniprot
Q8CCI2
resolver
uniprot_entry
TICRR_MOUSE
resolver
uniprot_sec
B2RY55
resolver
uniprot_sec
Q8C9N4
resolver
uniprot_sec
Q8CCI2
resolver
amino_acid_sequence
MACCHKVMLLVDTAGVSAPHSPARRAALRLLTYLSCRFGLARVHWTFKFFDSQGARSRPSRVSDFRELGSRSWEDFEEELEARLGDRPPGAHLPGPTPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDADGEAREAQAALGGFGNAVFLLAPCPHSQRELLQFVSGCEAQAQRVPLTPKQVMEKVLPKRVQEVMIARNITLYWVDTTERSKLWASPDHVGYWTVCELLHHGGGTILPAETWSLGFTKARETVLPCGGELSHKPHPSPWISALPIDATVNCLLYNSEYEASFPRIEGTLFLPVQGKEIEETWAISLEPLAMHQRHFQKPVRIVLRGSVAQWSLPVSSALGTDSWMLQSPEEHRSTQRLLFQELVSRLTAEEFHLVASVDPGEGWPPITGIISPFSANAMILTVFRAKEAEFQSHFLQTAATEGSQDTASLFSDVVDSVLNQSHNLFEDPASSAPCVPEWVQQELSHTSSWSPALVEKWFPFSNASGATSDLMESFWLLHAASPDNDESSKTESELTRCLSELYQRSHEESTVVNQERSRKKRGIPRTPVRQKMNTMSRSLKMLNVARLNVKAQKLHPDGSPDTAVEKGLQKAVIGRTADKLEDRGRILRSSKLKEFKTEEELLAYIHDNYQKAVATEEITLYSCAQNMVSTIKMFLKSKDIKELEVACLSHVNSNLLKTSKTLRQNLAGKMDTEDKVGECQLQVFLRLEMCEQCPSVLDRPDEVERIVEEVTDLLRLVCLTKDSAYLSEFLEEILRLYIGSIPGTIGQLYHSLGLKIPQKLAGVLPTGFFSDDSMSQESMSPPPSSSTHRSVSAITESEQLEELRTRSAKKRRKNALIRHKSIAEISQTLRQIEVPKVSKRATRNENSHSASIQLPVPRKDTIQEVTKVRRNLFNQEMLSPSKRGLKKGLPRSHSVSALECLHHKQDKFKKTKSSTFQGYCKLLTKSVAETPVHKQISRRLLHRQIKGRSSDPGPDIHVVEESPEKEDEMTLRRSPRIKQLSFSRTNSGSFYSVSQPKSRSVQRIHSSQQESEQRENFPVQSIQSPKTLLFGALSEIPSSSKKGSAQIKRSLRSMLDSEISTSYETPKKSNQKSPSFSKTTPRRFPRTAQTLLYTPERLQNSPTEMTSAEGTISEATIKTPSSHGYNSPFASKVTSQKTVSPAKEETSPPLTKLPSTPRESDVQPPQCSSDCTWPHSVNSSPEGPYYPASPPPMAGQARSQCLTPIRYSFRTPPRTALAGTSKQQEHQELPLPRASQTQEPPQGLEKKALKIPKKPAHTSTSPLSPEEHYSGCDVSPHQPRNSLSASPPPGELNWKEHQTSPSVTSSVSCPVPSTPPRTPQRMTCPIPPSPPSKLRRSCRKKSCPPQDFPECHPGPSAAPVLSSATSPGAVTGSREEQSQFSEGQSYLGTGFRSDCHVSSPVLTASDTKCLPLIDEAQLHGLKNQEVKSGILPGEEGEEPESTIADELPSVSDPGILVPAPSSVSSSSELLPYPLCCTADGKQRQDAAQQGSPRASEATSSPQTYEVELEMQASGLPKLRIKKIDPGVLLEAEALGKEAPLGEEGALPALCMPKASKSSGRTEHPYLSPPCLRPSHSTPGKNGGQTFICQSCTPSRCPPSTPSPFQADAGVSWTPSPKQSGKTTPEIIKDWPRRKRAVDCSAGPSAGRGEASMDLPGSLSLLEPEPEGKERSLEQDLSKVLISEEFELEGVCQLPDQSPPKDSASVTEETSWGQFGLGRKRFLSAKEESEYKVKRVCDSLSEDPQASKQKECSPRWSALPLHSVGDDEVFVSGSTPPSGCMVRSCLSASGLQALTQSPLLFQGRTPSSHSTDTRDEEVDVFPSTAEESPFSHTLSRKRPFRTYTRKKLIS
uniprot
proteins
function
FUNCTION: Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
208335
uniprot
proteins
protein_family
Treslin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1889
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Associates with chromatin.
uniprot
proteins