Shpk
entrez
74637
canonical
uniprot
Q9D5J6
canonical
ensembl
ENSMUSG00000005951
resolver
ensp
ENSMUSP00000006105
resolver
enst
ENSMUST00000006105
resolver
genesymbol
Shpk
resolver
genesymbol_syn
Carkl
resolver
uniprot
Q5SSE0
resolver
uniprot_entry
SHPK_MOUSE
resolver
uniprot_sec
Q5SSE0
resolver
amino_acid_sequence
MASRPVTLGIDLGTTSVKAALLEAAPSLPSGFVVLASCARAARAETESAVAGPQGREQDVTRIIQALNECLDALPRQQLQRVRGIGVSGQMHGILFWKAGQGCEWMEGGPAFVFEPRAVSHLVTWQDGRCNSSFLASLPKPDSHLSVATGFGCATIFWLLKNSPEFLKSYDAAGTIQDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNLDTLEKAGFPIHLLPDIAEPGSMAGRTSHTWFEIPKGTQVGIALGDLQASVYSCMGQRTDAVLNISTSVQLAASMPVGFQPLQTPDPAAPVAFFPYFDRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAAQQKDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPFQQLKEWGVARVVGSGSALSRNEVLKQEVQRAFPFPVCFGQDVDAAFGAALVMLQRDLSQKEP
uniprot
proteins
ec_number
2.7.1.14
uniprot
proteins
function
FUNCTION: Acts as a modulator of macrophage activation through control of glucose metabolism. {ECO:0000269|PubMed:18775706, ECO:0000269|PubMed:22682222}.
uniprot
proteins
mass_dalton
51303
uniprot
proteins
mutagenesis
MUTAGEN 14; /note="T->M: Decreases sedoheptulose kinase activity; when associated with K-15."; /evidence="ECO:0000269|PubMed:22682222"; MUTAGEN 15; /note="T->K: Decreases sedoheptulose kinase activity; when associated with M-14."; /evidence="ECO:0000269|PubMed:22682222"; MUTAGEN 125; /note="W->D: Decreases sedoheptulose kinase activity."; /evidence="ECO:0000269|PubMed:22682222"; MUTAGEN 126; /note="Q->K: Decreases sedoheptulose kinase activity."; /evidence="ECO:0000269|PubMed:22682222
uniprot
proteins
protein_family
FGGY kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18775706
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22682222
uniprot
proteins
sequence_length
476
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22682222}.
uniprot
proteins