A3galt2
entrez
215493
canonical
uniprot
Q3V1N9
canonical
ensembl
ENSMUSG00000028794
resolver
ensp
ENSMUSP00000030585
resolver
genesymbol
A3galt2
resolver
genesymbol_syn
Igb3s
resolver
uniprot
B2KGX5
resolver
uniprot
B2KGX6
resolver
uniprot
M9MMK2
resolver
uniprot_entry
A3LT2_MOUSE
resolver
uniprot_sec
B2KGX5
resolver
uniprot_sec
B2KGX6
resolver
uniprot_sec
M9MMK2
resolver
amino_acid_sequence
MALGTELGVSWPGSHGSCREQEGQRQRGPGKPTWGLSRAKKRLLWRFFLSAFGFLGLYHYRFIIIRLIEGSIPMGTCPTAIMPLPRDNFTGVLHHWARPEVLTCTSWGAPIIWDGTFDPHVAQQEARRRNLTIGLTVFAVGRYLEKYLEHFLVSAEQHFMVGQNVVYYVFTDRPEAVPYVALGQGRLLRAKPVQRERRWQDVSMARMPTLHEALGGQLGQEADFVFCLDVDQYFTGNFGPEVLADLVAQLHAWHYRWPRWLLPYERDKRSAAALSLSEGDFYYHAAVFGGSVAALLKLTAHCATGQQLDHKRGIEALWHDESHLNKFFWLNKPTKLLSPEFCWAEEIIWRREIHHPRLLWAPKEYTLVRN
uniprot
proteins
ec_number
2.4.1.87
uniprot
proteins
function
FUNCTION: Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo-series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and is solely responsible for initiating the synthesis of isoglobo-series glycosphingolipids. {ECO:0000269|PubMed:15539565, ECO:0000269|PubMed:16456004}.
uniprot
proteins
mass_dalton
42649
uniprot
proteins
protein_family
Glycosyltransferase 6 family
uniprot
proteins
pubmed
15539565
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16456004
uniprot
proteins
pubmed
17372206
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
370
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:A0A4Z3}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:A0A4Z3}. Note=Also found in numerous large vesicles throughout the cytoplasm of the soma. {ECO:0000250|UniProtKB:A0A4Z3}.
uniprot
proteins
transmembrane_region
TRANSMEM 43..65; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins