Trmt2b
entrez
215201
canonical
uniprot
Q8BQJ6
canonical
ensembl
ENSMUSG00000067369
resolver
ensp
ENSMUSP00000084819
resolver
ensp
ENSMUSP00000084820
resolver
ensp
ENSMUSP00000108878
resolver
ensp
ENSMUSP00000171533
resolver
ensp
ENSMUSP00000344585
resolver
enst
ENSMUST00000087540
resolver
enst
ENSMUST00000087541
resolver
enst
ENSMUST00000113252
resolver
genesymbol
Trmt2b
resolver
uniprot
F6RS51
resolver
uniprot
Q8C8J3
resolver
uniprot
Q8CE55
resolver
uniprot_entry
F6RS51_MOUSE
resolver
uniprot_entry
Q8C8J3_MOUSE
resolver
uniprot_entry
TRM2B_MOUSE
resolver
uniprot_sec
Q8CE55
resolver
amino_acid_sequence
MHNPRLFLSRAGFFSKPGLLPWDTGRPPDLSQSLLGRAYKGSFTSVIAKKHPSRQKYQKKQRHCRDDSWQERLADVVTPLWRLSYEAQLKVKFEAQKKLLQSLESHLKVLHGVSDTVAAHQSEGLRCLLHPIIPSPTTTGYRNKSTFSVYRSPDGNPKTVGYYLGTWKDGNVVCLPCNHLKNIPEKHSQVAQYYEVFLRQSSVEPCLLFHEGGHWRELVVRTNRQGHTMAIVTFHPQGLSEEEVCVQKVTLKDFFTKGPGAICELTSLYFQESTMTRCSHQQSPYQLLFGEPHIFEDLLGLKIRISPDAFFQINTAGAEMLYRIIGELSGVNSESLLLDICCGTGVIGLSVAQRASQVHGIELVEQAVEDARWTAAFNGVTNCEFHAGRAETILPQLLKSQKDEKLTVAVVNPARAGLHYRVVRAIRNCRTIHTLVFVSCKPHGESTRNFIELCCPPNSAKQLLGDPFVLREAVPVDLFPHTPHCELVLLFTR
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
ec_number
2.1.1.35
uniprot
proteins
function
FUNCTION: Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and 12S rRNA (PubMed:31736397). Catalyzes the methylation of uridine at position 54 (m5U54) in all tRNAs (PubMed:31736397). Specifically methylates the uridine in position 425 of 12S rRNA (m5U425) (PubMed:31736397). Does not affect RNA stability or mitochondrial translation (By similarity). {ECO:0000250|UniProtKB:Q96GJ1, ECO:0000269|PubMed:31736397}.
uniprot
proteins
mass_dalton
55476
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
RNA M5U methyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
31736397
uniprot
proteins
sequence_length
493
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q96GJ1}.
uniprot
proteins