Exoc8
entrez
245709
canonical
uniprot
O54924
canonical
ensembl
ENSRNOG00000071599
resolver
ensembl
ENSRNOG00055022082
resolver
ensembl
ENSRNOG00060024218
resolver
ensembl
ENSRNOG00065019454
resolver
ensp
ENSRNOP00000026757
resolver
ensp
ENSRNOP00000101058
resolver
ensp
ENSRNOP00000102714
resolver
ensp
ENSRNOP00000108001
resolver
ensp
ENSRNOP00000112365
resolver
ensp
ENSRNOP00055030989
resolver
ensp
ENSRNOP00060034752
resolver
ensp
ENSRNOP00065026184
resolver
enst
ENSRNOT00000026757
resolver
enst
ENSRNOT00000138617
resolver
enst
ENSRNOT00000153061
resolver
enst
ENSRNOT00000157508
resolver
enst
ENSRNOT00000170200
resolver
enst
ENSRNOT00055037948
resolver
enst
ENSRNOT00060041906
resolver
enst
ENSRNOT00065032759
resolver
genesymbol
Exoc8
resolver
genesymbol_syn
Exo84
resolver
uniprot_entry
EXOC8_RAT
resolver
amino_acid_sequence
MSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRVQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLALLPAAAAGASTGEDTAGAGPRERGAAQAGFLPGPAGVPREGPGTGEEGKQRTLTTLLEKVEGCRDLLETPGQYLVYNGDLVEYEADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEETKRALSDKRRREQEEAAALRAPPPVTSKGSNPFEDEAEEELATPEAEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPSVKELRAKVDERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIRLGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFETDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGEIGLDLTFIIHALLVKDIQGALLSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMRSCGVSNFEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEVILVAVQHVDYSLRCEQDPEKKTFIRQNASFLYDTVLPVVERRFEEGVGKPAKQLQDLRNASRLLRVNPESTTSVV
uniprot
proteins
function
FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
uniprot
proteins
mass_dalton
81043
uniprot
proteins
mutagenesis
MUTAGEN 228; /note="A->W: Strongly reduces interaction with RALA."; /evidence="ECO:0000269|PubMed:15920473"; MUTAGEN 233; /note="K->W: Strongly reduces interaction with RALA."; /evidence="ECO:0000269|PubMed:15920473
uniprot
proteins
protein_family
EXO84 family
uniprot
proteins
pubmed
12954101
uniprot
proteins
pubmed
15920473
uniprot
proteins
pubmed
21658605
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9405631
uniprot
proteins
sequence_length
716
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12954101}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:12954101}. Cell projection, growth cone {ECO:0000269|PubMed:12954101}. Cell projection {ECO:0000269|PubMed:21658605}. Note=Binds lipids with phosphatidylinositol 3,4,5-trisphosphate groups (By similarity). Perinuclear in undifferentiated PC12 cells. Redistributes to growing neurites and growth cones during NGF-induced neuronal differentiation (PubMed:12954101). Localizes at the leading edge of migrating cells (PubMed:21658605). {ECO:0000250, ECO:0000269|PubMed:12954101, ECO:0000269|PubMed:21658605}.
uniprot
proteins