Ccdc8
entrez
494320
canonical
uniprot
P62521
canonical
ensembl
ENSRNOG00000027936
resolver
ensp
ENSRNOP00000068789
resolver
ensp
ENSRNOP00000106529
resolver
enst
ENSRNOT00000029810
resolver
enst
ENSRNOT00000147970
resolver
genesymbol
Ccdc8
resolver
uniprot
A0A0G2JTP3
resolver
uniprot
Q6P9Z5
resolver
uniprot_entry
A0A0G2JTP3_RAT
resolver
uniprot_entry
CCDC8_RAT
resolver
uniprot_sec
Q6P9Z5
resolver
amino_acid_sequence
MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAVFRERLIQFLQEEGRTLEDVARIIEKSTPHPPQPPKKAKVPRVRRVPQMVTPPLRLVVGTYDSSNGSDSELSDFDTSKVKGNRGSGKTRKVRKMPVSYLGSKFLGSDESEDDQELVEAFLRRGEKKPSAPPPRRRVNLPVPMFENNLGPQPSKGDRWREYVSQVSWGKLKQRVRGWAPRSGSEVGQAQQSSIAERAGEMRHSHTSPDLDDSSRNTGDLSDQTLITRRWKPKIKWVSLRRCRKEQVPPLAHGTAEEPPEAAENQGAGAAAEHGVEAAASQRPEAAASPRAEAAANPRAEATANPRAEAAANPRAEAAASPRAEAAANPRAEAAANPRAEATANPRAEAAANPRAEATANPRAEAAVNPRTEAAVNPRTEAAANPRAEAAVNPRAEATASPRAEAEVNQKTEATASPRAETAASPRVEAAASLRVEAAASPRAEATVSPRAEAVATPRAETAASARVEAAANLRAGVLPDQRAEAIDSQRAEGPVNQSTGATENQRVEVLADQRAGVLHDQREEAGPQAILEASADSGSRARKQVKTVRFQTPGRFSWFHMRRKAFWHTPRLPTLPKRGPRAGAGEARSLRVLRADTRADMEHREQEEQL
uniprot
proteins
function
FUNCTION: Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Required for localization of CUL7 to the centrosome. {ECO:0000250|UniProtKB:Q9H0W5}.
uniprot
proteins
mass_dalton
69589
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
643
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H0W5}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9H0W5}.
uniprot
proteins