Phgdh
entrez
58835
canonical
uniprot
O08651
canonical
ensembl
ENSRNOG00000019328
resolver
ensp
ENSRNOP00000053019
resolver
enst
ENSRNOT00000056173
resolver
genesymbol
Phgdh
resolver
uniprot
Q546Q9
resolver
uniprot_entry
SERA_RAT
resolver
uniprot_sec
Q546Q9
resolver
amino_acid_sequence
MAFANLRKILISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHSPGVPGEQGIGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLLFRAQPSDPVMLPTMIGLLAEAGVQLLSYQTSKVSDGDTWHVMGLSSLLPSLDAWKQHVSEAFQFCF
uniprot
proteins
ec_number
1.1.1.95
uniprot
proteins
function
FUNCTION: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. {ECO:0000269|PubMed:9163325}.
uniprot
proteins
mass_dalton
56493
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3. {ECO:0000269|PubMed:9163325}.
uniprot
proteins
protein_family
D-isomer specific 2-hydroxyacid dehydrogenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9163325
uniprot
proteins
sequence_length
533
uniprot
proteins