Srpx2
entrez
317181
canonical
uniprot
B5DF94
canonical
ensembl
ENSRNOG00000003715
resolver
ensembl
ENSRNOG00055014592
resolver
ensembl
ENSRNOG00060019766
resolver
ensembl
ENSRNOG00065006239
resolver
ensp
ENSRNOP00000085502
resolver
ensp
ENSRNOP00055020454
resolver
ensp
ENSRNOP00060027952
resolver
ensp
ENSRNOP00065006838
resolver
enst
ENSRNOT00055025023
resolver
enst
ENSRNOT00060034112
resolver
enst
ENSRNOT00065009528
resolver
genesymbol
Srpx2
resolver
uniprot_entry
SRPX2_RAT
resolver
amino_acid_sequence
MKTGSLTQRGALLLLLLLAPAVTPTWYAGSGYSPDESYNEVYAEEVPDTRALDYRVPRWCYTLNIQDGEATCYSPRGGNYHSSLGTRCELSCDRGFRLIGRKSVQCLPSRRWSGTAYCRQMRCHTLPFITSGTYTCTNGMLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKIAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPILKPPQHGYLTCSSAGDNYGAICEYHCDGGYERQGTPSRVCQSSRQWSGSPPVCTPMKINVNVNSAAGLLDQFYEKQRLLIVSAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSAGIIEELRQFQRLTRSYFNMVLIDKQGIDRERYMEPVTPEEIFTFIDDYLLSNQELARRAEQRDVCE
uniprot
proteins
function
FUNCTION: Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF (By similarity). Promotes synapse formation. {ECO:0000250|UniProtKB:O60687, ECO:0000250|UniProtKB:Q8R054, ECO:0000269|PubMed:24179158}.
uniprot
proteins
mass_dalton
52853
uniprot
proteins
mutagenesis
MUTAGEN 73; /note="Y->S: Dominant negative; secreted and retains ability to homooligomerize."; /evidence="ECO:0000269|PubMed:24179158
uniprot
proteins
post_translational_modification
PTM: Contains chondroitin sulfate chains. {ECO:0000250|UniProtKB:O60687}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24179158
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:O60687}. Cytoplasm {ECO:0000250|UniProtKB:O60687}. Cell surface {ECO:0000269|PubMed:24179158}. Synapse {ECO:0000269|PubMed:24179158}.
uniprot
proteins