DUSP10
entrez
11221
canonical
uniprot
Q9Y6W6
canonical
ensembl
ENSG00000143507
resolver
ensp
ENSP00000355866
resolver
ensp
ENSP00000784299
resolver
genesymbol
DUSP10
resolver
genesymbol_syn
MKP5
resolver
hgnc
HGNC:3065
resolver
uniprot
D3DTB4
resolver
uniprot
Q6GSI4
resolver
uniprot
Q9H9Z5
resolver
uniprot_entry
DUS10_HUMAN
resolver
uniprot_sec
D3DTB4
resolver
uniprot_sec
Q6GSI4
resolver
uniprot_sec
Q9H9Z5
resolver
amino_acid_sequence
MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSANPGSNSHPPVIATTVVSLKAANLTYMPSSSGSARSLNCGCSSASCCTVATYDKDNQAQTQAIAAGTTTTAIGTSTTCPANQMVNNNENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38. {ECO:0000269|PubMed:10391943, ECO:0000269|PubMed:10597297, ECO:0000269|PubMed:22375048}.
uniprot
proteins
mass_dalton
52642
uniprot
proteins
mutagenesis
MUTAGEN 180..181; /note="FM->DD: Reduced enzyme activity with MAPK14."; /evidence="ECO:0000269|PubMed:22375048"; MUTAGEN 203..204; /note="RR->AA: Strongly reduced affinity for MAPK14. Almost abolishes enzyme activity with MAPK14."; /evidence="ECO:0000269|PubMed:22375048
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
10391943
uniprot
proteins
pubmed
10597297
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16806267
uniprot
proteins
pubmed
17400920
uniprot
proteins
pubmed
22375048
uniprot
proteins
pubmed
29043977
uniprot
proteins
sequence_length
482
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
uniprot
proteins