Or2at4
entrez
259066
canonical
uniprot
E9Q518
canonical
ensembl
ENSMUSG00000073998
resolver
ensp
ENSMUSP00000095864
resolver
ensp
ENSMUSP00000151459
resolver
enst
ENSMUST00000098264
resolver
enst
ENSMUST00000220185
resolver
genesymbol
Or2at4
resolver
genesymbol_syn
Olfr520
resolver
uniprot_entry
E9Q518_MOUSE
resolver
amino_acid_sequence
MEATTCNGSVDGSTVFYLVGIPSLPEPFYLPVFFLFLLFYLLILVGNALILVAVVAERSLHKPMYFFLINLSALDILFTTTTVPKMLSLLLLGDRFLSFPACLLQMYLFQSFTCSEAFILVVMAYDRYVAICRPLHYPVHMTPQTNTALAASAWITALLLPVPAVVKTSQMVYNDIAYIYHCFCDHLALVQSSCSDTTPQTLMGFCIAMVVSFLPLLLVLLSYVRILTSVLRINSKEGRSKAFSTCSSHLLVVGTYYSSIAIAYVAYRANLPLDFHIMGNVVYSILTPILNPLIYTLRNKDVKVAITKIVYLKGMM
uniprot
proteins
function
FUNCTION: Olfactory receptor activated by the synthetic sandalwood odorant sandalore (By similarity). Endogenous ligand is unknown (By similarity). The activity of this receptor is probably mediated by G proteins which induce elevation of intracellular Ca(2+), a cAMP-dependent pathway and phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and p38 MAPKs (By similarity). Activation of OR2AT4 induces proliferation, migration, and re-epithelialization during wound-healing processes of keratinocytes (By similarity). {ECO:0000250|UniProtKB:A6NND4}.
uniprot
proteins
mass_dalton
35263
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
316
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:A6NND4}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 32..52; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 63..83; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 146..166; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 246..266; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 277..297; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins