Mgarp
entrez
67749
canonical
uniprot
Q8VI64
canonical
ensembl
ENSMUSG00000037161
resolver
ensp
ENSMUSP00000040703
resolver
enst
ENSMUST00000038154
resolver
genesymbol
Mgarp
resolver
genesymbol_syn
Cesp1
resolver
genesymbol_syn
Hummr
resolver
genesymbol_syn
Osap
resolver
uniprot
Q96EB2
resolver
uniprot
Q9D9Y5
resolver
uniprot_entry
HUMMR_MOUSE
resolver
uniprot_sec
Q96EB2
resolver
uniprot_sec
Q9D9Y5
resolver
amino_acid_sequence
MYLRRAVSKTLALPRRAPPGPAPLGKDASLRRMSSRKFPGTSGSNMIYYLVVGVTVSAGGYYTYKALTSKQVRRTEHVAEPKEQTKAELQPLPGEKEEHVAEAEQVCSEPGDTAVTEAESVDAEEVPEAAVVLPEESQASAPSEVPAEAAVVEASLSSSEPELKITEASLVETTESVPESTQEVESAAPDQDDVCNEGADTSQEGADTSQEGADTSQEGADTTKEEADNSKEAEGTTTEDPRSISEESAELEESPPLGSEPPAQPESQEEETQVTEETASPQG
uniprot
proteins
function
FUNCTION: Plays a role in the trafficking of mitochondria along microtubules (PubMed:19325000). Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia (PubMed:19325000). Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion (PubMed:19325000). Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (PubMed:19528298). Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons (PubMed:24323429). {ECO:0000269|PubMed:19325000, ECO:0000269|PubMed:19528298, ECO:0000269|PubMed:24323429}.
uniprot
proteins
mass_dalton
29925
uniprot
proteins
pubmed
10919256
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16565373
uniprot
proteins
pubmed
19325000
uniprot
proteins
pubmed
19528298
uniprot
proteins
pubmed
20107910
uniprot
proteins
pubmed
21447634
uniprot
proteins
pubmed
24323429
uniprot
proteins
pubmed
31202457
uniprot
proteins
sequence_length
283
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:19325000, ECO:0000269|PubMed:19528298, ECO:0000269|PubMed:20107910, ECO:0000269|PubMed:24323429}. Mitochondrion outer membrane {ECO:0000269|PubMed:19528298}; Single-pass type IV membrane protein {ECO:0000305|PubMed:19528298}; Cytoplasmic side {ECO:0000305|PubMed:19528298}. Mitochondrion inner membrane {ECO:0000269|PubMed:31202457}; Single-pass type IV membrane protein {ECO:0000305|PubMed:31202457}; Cytoplasmic side {ECO:0000305|PubMed:31202457}. Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion. {ECO:0000269|PubMed:19528298}.
uniprot
proteins
transmembrane_region
TRANSMEM 42..64; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins