Sgsm3
entrez
362963
canonical
uniprot
Q6P6R7
canonical
ensembl
ENSRNOG00000018745
resolver
ensp
ENSRNOP00000025381
resolver
ensp
ENSRNOP00000080335
resolver
enst
ENSRNOT00000025382
resolver
genesymbol
Sgsm3
resolver
genesymbol_syn
Bdif1
resolver
genesymbol_syn
Rutbc3
resolver
uniprot
F1LQU9
resolver
uniprot
Q76KK4
resolver
uniprot_entry
F1LQU9_RAT
resolver
uniprot_entry
SGSM3_RAT
resolver
uniprot_sec
Q76KK4
resolver
amino_acid_sequence
MSGNHTPSASGPFSALTPSIWPQEILAKSSQKEDSSEPEICYDEFGFRVDKEGSEPGCSQMAGTPLVEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKKNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLFFYEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMQLAGSLTDVAVETQRRKHLAYLIADQGQTLGTSTTTSLSQVVRRRTQRRKSGITSLLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACLRSHRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNVTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREEEKQPLKEGVQDMLVKHHLFSWDIDG
uniprot
proteins
function
FUNCTION: GTPase-activating protein (GAP) specific for Rab5 small GTPase for which it accelerates the intrinsic GTP hydrolysis rate, thereby controlling trafficking through the early endocytic pathway. May play a cooperative role in NF2-mediated growth suppression of cells. {ECO:0000250|UniProtKB:Q96HU1}.
uniprot
proteins
mass_dalton
85188
uniprot
proteins
protein_family
Small G protein signaling modulator family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21453730
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
749
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8VCZ6}.
uniprot
proteins