Cfap263
entrez
244608
canonical
uniprot
Q8C5T8
canonical
ensembl
ENSMUSG00000036598
resolver
ensp
ENSMUSP00000049497
resolver
enst
ENSMUST00000041569
resolver
genesymbol
Cfap263
resolver
genesymbol_syn
Ccdc113
resolver
uniprot_entry
CF263_MOUSE
resolver
amino_acid_sequence
MSEEDSDSVITDSQAEEEGELPVIQLCGLVEELSYGNSALKTETEMFEKYYSRLEPRDHRMTRLSDIKITAAEFSQLRSRRKSKARGGLDRTLGLTVEQKLELVQKELEDTRDEIRHMRANAERDLQHHEAIIEEADIRWNEVQKAVHEFEKDILKTISKKKGSILATQKVMKYIEDMNRRRDNIKDKLCLKNVSLKVQRKKMLSQLRQKEEVGEALHDVDFQQLKIENAQFLETIEARNKELIQLKLASGNTLQVLNTYKNKLHRAMEIYVNLDKEILLRNELLGKIEKETIQAEEDRAKAHILNDKLRKQLAEFRAPQVMMYVKEKILNGELEKTIKMWERKVEIAEMSLKGYRKAWNKMKTSDEQLQIIRPPGK
uniprot
proteins
function
FUNCTION: Component of centriolar satellites contributing to primary cilium formation (By similarity). In complex with CFAP263, acts as a regulator of ciliary beating that connects radial spoke 3 (RS3) to the inner dynein arm (IDA) and the nexin-dynein regulatory complex (N-DRC). The complex is positioned parallel to N-DRC and forms a connection between the arch at the base of RS3, the IDA tail and N-DRC (By similarity). {ECO:0000250|UniProtKB:Q22KK0, ECO:0000250|UniProtKB:Q9H0I3}.
uniprot
proteins
mass_dalton
44215
uniprot
proteins
protein_family
CFAP263 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
377
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000250|UniProtKB:Q9H0I3}. Cell projection, cilium {ECO:0000250|UniProtKB:Q22KK0}. Note=Colocalized with HAP1 at centriolar satellites. Centriolar satellite localization requires PCM1 (By similarity). Localizes at cilium but not at the ciliary tips (By similarity). {ECO:0000250|UniProtKB:Q22KK0, ECO:0000250|UniProtKB:Q9H0I3}.
uniprot
proteins