Abhd3
entrez
106861
canonical
uniprot
Q91ZH7
canonical
ensembl
ENSMUSG00000002475
resolver
ensp
ENSMUSP00000113137
resolver
ensp
ENSMUSP00000249349
resolver
ensp
ENSMUSP00000249369
resolver
ensp
ENSMUSP00000354418
resolver
genesymbol
Abhd3
resolver
genesymbol_syn
Labh3
resolver
uniprot
Q3UNF7
resolver
uniprot_entry
ABHD3_MOUSE
resolver
uniprot_sec
Q3UNF7
resolver
amino_acid_sequence
MQRLAMDLRVLSRELALYLEHQVRVGFFGSGVGLSLILGFSVAYACYYLSSIAKKPQLVIGGESFSRFLQDHCPVVTETYYPTVWCWESRGQTLLRPFITSKPPVQYRNELIKTADGGQISLDWFDNNNSAYYVDASTRPTILLLPGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGESLLTPRTYCCANTEDLEAVVHHVHSLYPGAPFLAAGVSMGGMLLLNYLGKIGSKTPLMAAATFSVGWNTFACSESLERPLNWLLFNYYLTTCLQSSVKKHRHMFVEQIDMDQVMKAKSIREFDKRFTAVMFGYRTLDDYYTDASPNRRLKSVGIPVLCLNATDDVFSPSHAIPIETAKQNPNVALVLTAYGGHIGFLEGIWPRQCTYMDRVFKQFVQAMVEHGHELSNM
uniprot
proteins
ec_number
3.1.1.32
uniprot
proteins
ec_number
3.1.1.4
uniprot
proteins
function
FUNCTION: Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids. {ECO:0000269|PubMed:21926997}.
uniprot
proteins
mass_dalton
46232
uniprot
proteins
mutagenesis
MUTAGEN 220; /note="S->A: Loss of phospholipase activity."; /evidence="ECO:0000269|PubMed:21926997
uniprot
proteins
protein_family
AB hydrolase 4 family
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
pubmed
11922611
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21926997
uniprot
proteins
sequence_length
411
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins