CCDC38
entrez
120935
canonical
uniprot
Q502W7
canonical
ensembl
ENSG00000165972
resolver
ensp
ENSP00000345470
resolver
enst
ENST00000344280
resolver
genesymbol
CCDC38
resolver
hgnc
HGNC:26843
resolver
uniprot
Q8N835
resolver
uniprot_entry
CCD38_HUMAN
resolver
uniprot_sec
Q8N835
resolver
amino_acid_sequence
MSSNLLPTLNSGGKVKDGSTKEDRPYKIFFRDLFLVKENEMAAKETEKFMNRNMKVYQKTTFSSRMKSHSYLSQLAFYPKRSGRSFEKFGPGPAPIPRLIEGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDALAFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMKYGFFLLQMSPKHWQIQQALKRAQASKSKANIILPKILAKLSLHSSNKEGILEESGRTAVLSEDASQGRDSQGKPSRSLTRTPEKKKSNLAESFGSEDSLEFLLDDEMDVDLEPALYFKEPEELLQVLRELEEQNLTLFQYSQDVDENLEEVNKREKVIQDKTNSNIEFLLEQEKMLKANCVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGLNPIQKLVKVESRLVELCDLIESIPKENVEAIERMKQKEWRQKFRDEKMKEKQRHQQERLKAALEKAVAQPKKKLGRRLVFHSKPPSGNKQQLPLVNETKTKSQEEEYFFT
uniprot
proteins
function
FUNCTION: Essential for male fertility. Required for sperm flagellum biogenesis. Also required for acrosome biogenesis. Required for the attachment of developing acrosomes to the nucleus during spermiogenesis and may be involved in the transport of fibrous sheath components. {ECO:0000250|UniProtKB:Q8CDN8}.
uniprot
proteins
mass_dalton
65315
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
25074808
uniprot
proteins
sequence_length
563
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:25074808}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8CDN8}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q8CDN8}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8CDN8}. Note=Localizes to the sperm flagellum, manchette and the perinuclear region of the sperm head. {ECO:0000250|UniProtKB:Q8CDN8}.
uniprot
proteins