Lypd6b
entrez
71897
canonical
uniprot
Q9D7F2
canonical
ensembl
ENSMUSG00000026765
resolver
ensp
ENSMUSP00000028103
resolver
ensp
ENSMUSP00000205550
resolver
ensp
ENSMUSP00000205551
resolver
ensp
ENSMUSP00000205552
resolver
ensp
ENSMUSP00000205553
resolver
ensp
ENSMUSP00000205557
resolver
ensp
ENSMUSP00000205559
resolver
ensp
ENSMUSP00000205562
resolver
ensp
ENSMUSP00000205575
resolver
genesymbol
Lypd6b
resolver
uniprot
A0JNT6
resolver
uniprot_entry
LPD6B_MOUSE
resolver
uniprot_sec
A0JNT6
resolver
amino_acid_sequence
MLLLCHILAVTILQILIISENWVFAKNINFYNVRPPLDPTPFPNSFKCFTCENAGDNYNCNRWAEDKWCPQDTQYCLTVHHFTSHGRSTSITKKCASKNECHFVGCRHSRDSEHTECRSCCEGMICNVELPTNHTNAVFAVMHAQRTSGSSVSSVPSPYLLVLAWLFMLPLL
uniprot
proteins
function
FUNCTION: Likely acts as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence. However, according to another report in vitro it can weakly inhibits alpha-7 nAChRs. {ECO:0000250|UniProtKB:Q8NI32}.
uniprot
proteins
mass_dalton
19528
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
172
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
uniprot
proteins