Spata7
entrez
104871
canonical
uniprot
Q80VP2
canonical
ensembl
ENSMUSG00000021007
resolver
ensp
ENSMUSP00000045827
resolver
ensp
ENSMUSP00000098704
resolver
ensp
ENSMUSP00000098705
resolver
ensp
ENSMUSP00000259009
resolver
enst
ENSMUST00000048402
resolver
enst
ENSMUST00000101144
resolver
enst
ENSMUST00000101146
resolver
genesymbol
Spata7
resolver
uniprot
F6WL33
resolver
uniprot
F6WL42
resolver
uniprot
Q3TTL3
resolver
uniprot
Q3U5D0
resolver
uniprot
Q8BK23
resolver
uniprot_entry
F6WL33_MOUSE
resolver
uniprot_entry
F6WL42_MOUSE
resolver
uniprot_entry
Q3TTL3_MOUSE
resolver
uniprot_entry
Q3U5D0_MOUSE
resolver
uniprot_entry
SPAT7_MOUSE
resolver
uniprot_sec
Q8BK23
resolver
amino_acid_sequence
MDGSRRVRATSVLPRYSPPCLFTGHLSTKSNAFCTDSSSLRLSTLQLVKNHMAIHYNKILSAKAAVDCSIPVSVNTSIKYADQQRREKLRKELARCEKEFKLSKSAMQTNSKMNSKFFVNSLQKPSGEPQDQDVFIEEMTRYPSFSKSLIPSSEGLHLSLPESSKMLMSGTQKHASTSPSRHSGCGHGCDRRPRSAHQFQVALAKTPSGDLLEKHSDLFSNKQSPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFSDQRMEAETQTELSSFNSELGTAEKTSSKDSEVNINQVPNYTRNGAEDKIAPLPSQGQNLAWDSIQDGILQQSSERASCKLSTEFSPDSKIYSDEEELLYLSFMENVTDEILKLGLFSNRFLERLFERHIKKNKHHLEEGKMRYLLHGLKVDLGCISEEDPAKQKHFRMLNQLHFQKALISRENEFVSDEETVSHHERQQYQEALDMLSAVPKDENKMFSLPGEFLIPAHKVKHSEGVIIQQVNDETDNEASPWNENNPSVSDSVIDQETSVDVIEGDSDFERAETSRELCCLSTSLSPSGPFPSINGGSNHGKELSTLRIMGMSIED
uniprot
proteins
function
FUNCTION: Involved in the maintenance of both rod and cone photoreceptor cells (PubMed:25398945, PubMed:29100828, PubMed:29899041). Required for photoreceptor-specific localization of proximal connecting cilium (CC) proteins RPGR, AHI1, NPHP1, NPHP4, and RPGRIP1 at the distal CC, a photoreceptor-specific extension of the primary cilium transition zone (PubMed:25398945, PubMed:29100828, PubMed:29899041). Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration (PubMed:25398945, PubMed:29899041). {ECO:0000269|PubMed:25398945, ECO:0000269|PubMed:29100828, ECO:0000269|PubMed:29899041}.
uniprot
proteins
mass_dalton
65655
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19268277
uniprot
proteins
pubmed
25398945
uniprot
proteins
pubmed
29100828
uniprot
proteins
pubmed
29899041
uniprot
proteins
sequence_length
582
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:29899041}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:29100828, ECO:0000269|PubMed:29899041}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9P0W8}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:25398945, ECO:0000269|PubMed:29100828, ECO:0000269|PubMed:29899041}. Note=Localizes to the microtubule network. {ECO:0000250|UniProtKB:Q9P0W8}.
uniprot
proteins