Paip2
entrez
361309
canonical
uniprot
Q6AXZ0
canonical
ensembl
ENSRNOG00000019934
resolver
ensembl
ENSRNOG00055023384
resolver
ensembl
ENSRNOG00060026721
resolver
ensembl
ENSRNOG00065000632
resolver
ensembl
ENSRNOG00065012803
resolver
ensp
ENSRNOP00000026989
resolver
ensp
ENSRNOP00055032618
resolver
ensp
ENSRNOP00060038449
resolver
ensp
ENSRNOP00065000733
resolver
ensp
ENSRNOP00065016118
resolver
enst
ENSRNOT00000026989
resolver
enst
ENSRNOT00055040176
resolver
enst
ENSRNOT00060046279
resolver
enst
ENSRNOT00065000901
resolver
enst
ENSRNOT00065020913
resolver
genesymbol
Paip2
resolver
uniprot_entry
PAIP2_RAT
resolver
amino_acid_sequence
MKDPSRSSTSPSIINDDVIINGHSHEEDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY
uniprot
proteins
function
FUNCTION: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
14700
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation by the proteasome. {ECO:0000250|UniProtKB:Q9BPZ3}.
uniprot
proteins
protein_family
PAIP2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
124
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins