Elp6
entrez
363150
canonical
uniprot
B2RYG8
canonical
ensembl
ENSRNOG00000020847
resolver
ensembl
ENSRNOG00055007506
resolver
ensembl
ENSRNOG00060016837
resolver
ensembl
ENSRNOG00065007398
resolver
ensp
ENSRNOP00000028288
resolver
ensp
ENSRNOP00055009933
resolver
ensp
ENSRNOP00060023181
resolver
ensp
ENSRNOP00065008397
resolver
enst
ENSRNOT00000028288
resolver
enst
ENSRNOT00055012514
resolver
enst
ENSRNOT00060028808
resolver
enst
ENSRNOT00065011539
resolver
genesymbol
Elp6
resolver
uniprot_entry
ELP6_RAT
resolver
amino_acid_sequence
MFPELNNLLSITPDRTEQGKLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALVQSFSHYNIVGQKLGVSLTAARERGQLVFLEGLKSSVEVLFHSQEEPHPLQFLREAGAGNLQSLYTFIQDTLKPADSGESPWKCPVLLVDNLSVLLSLGVGAVAVLDFMQYCRATVCCELKGNVVALVHDTEGAEDEENNILLNGLSHQSHLILRTQGLATGFCKDVHGQLSILWRRSSQPTAQRARSLTYQYKIQDKNVSFFAKGMSRAVL
uniprot
proteins
function
FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Involved in cell migration (By similarity). {ECO:0000250|UniProtKB:Q0PNE2, ECO:0000250|UniProtKB:Q8BK75}.
uniprot
proteins
mass_dalton
29459
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. {ECO:0000250|UniProtKB:Q0PNE2}.
uniprot
proteins
protein_family
ELP6 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
266
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q0PNE2}. Nucleus {ECO:0000250|UniProtKB:Q0PNE2}. Note=Concentrates in the nucleus upon insulin stimulation. {ECO:0000250|UniProtKB:Q0PNE2}.
uniprot
proteins