Trim9
entrez
94090
canonical
uniprot
Q8C7M3
canonical
ensembl
ENSMUSG00000021071
resolver
ensp
ENSMUSP00000106149
resolver
ensp
ENSMUSP00000106151
resolver
ensp
ENSMUSP00000127081
resolver
ensp
ENSMUSP00000152147
resolver
ensp
ENSMUSP00000152496
resolver
ensp
ENSMUSP00000152692
resolver
ensp
ENSMUSP00000152887
resolver
ensp
ENSMUSP00000159335
resolver
ensp
ENSMUSP00000160250
resolver
ensp
ENSMUSP00000247122
resolver
ensp
ENSMUSP00000247123
resolver
ensp
ENSMUSP00000247124
resolver
ensp
ENSMUSP00000247125
resolver
ensp
ENSMUSP00000247126
resolver
ensp
ENSMUSP00000247127
resolver
ensp
ENSMUSP00000247128
resolver
ensp
ENSMUSP00000247131
resolver
ensp
ENSMUSP00000247133
resolver
ensp
ENSMUSP00000247134
resolver
ensp
ENSMUSP00000247143
resolver
ensp
ENSMUSP00000247146
resolver
ensp
ENSMUSP00000247147
resolver
ensp
ENSMUSP00000247157
resolver
ensp
ENSMUSP00000247164
resolver
ensp
ENSMUSP00000247166
resolver
ensp
ENSMUSP00000247171
resolver
ensp
ENSMUSP00000247176
resolver
ensp
ENSMUSP00000247177
resolver
ensp
ENSMUSP00000354321
resolver
enst
ENSMUST00000110522
resolver
enst
ENSMUST00000167755
resolver
enst
ENSMUST00000221306
resolver
enst
ENSMUST00000222603
resolver
enst
ENSMUST00000223160
resolver
genesymbol
Trim9
resolver
genesymbol_syn
Kiaa0282
resolver
uniprot
A0A1Y7VP88
resolver
uniprot
A0A6I8MWZ7
resolver
uniprot
E9Q524
resolver
uniprot
E9QLH4
resolver
uniprot
Q3TR28
resolver
uniprot
Q6ZQE5
resolver
uniprot
Q80WT6
resolver
uniprot
Q8C7Z4
resolver
uniprot
Q8CC32
resolver
uniprot
Q8CEG2
resolver
uniprot
Q99PQ3
resolver
uniprot_entry
A0A1Y7VP88_MOUSE
resolver
uniprot_entry
A0A6I8MWZ7_MOUSE
resolver
uniprot_entry
E9Q524_MOUSE
resolver
uniprot_entry
E9QLH4_MOUSE
resolver
uniprot_entry
Q3TR28_MOUSE
resolver
uniprot_entry
TRIM9_MOUSE
resolver
uniprot_sec
Q6ZQE5
resolver
uniprot_sec
Q80WT6
resolver
uniprot_sec
Q8C7Z4
resolver
uniprot_sec
Q8CC32
resolver
uniprot_sec
Q8CEG2
resolver
uniprot_sec
Q99PQ3
resolver
amino_acid_sequence
MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSRRASGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPPTHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRTMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVAADGYILELDDGSGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEAAGAHETKPMKDTDSEEQTLPFPVPSERLPLRRMSPFSSTLNLQPSFPGRSYFDFRSSPHQLSLHSSLQSLNAPGCNFETQSASYSQLVDIKKLLAVAWFAFDPGSAHSDIIFSNDNLTVTCSSYDDRVVLGKTGFSKGVHYWELTIDRYDNHPDPAFGVARIDVMKDMMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKTLTFFVNNEQQGPIAFENVEGLFFPAVSLNRNVQVSLWAPGLRACSGCYFKVCPGAVKSPQAPAP
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation (By similarity). Regulates filopodial dynamics in brain by promoting the ubiquitination and degradation of actin polymerase VASP; this activity is antagonized by TRIM67 (PubMed:31820781). May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. {ECO:0000250|UniProtKB:Q9C026, ECO:0000269|PubMed:31820781}.
uniprot
proteins
mass_dalton
90870
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:Q9C026}.
uniprot
proteins
post_translational_modification
PTM: Auto-ubiquitinated. Poly-ubiquitinated in cultured cells, whereas it is monoubiquitinated in vitro (By similarity). {ECO:0000250|UniProtKB:Q9C026}.
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
11331580
uniprot
proteins
pubmed
11960705
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20085810
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
31820781
uniprot
proteins
sequence_length
817
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20085810}. Cell projection, dendrite {ECO:0000269|PubMed:20085810}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q91ZY8}. Synapse {ECO:0000250|UniProtKB:Q91ZY8}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:31820781}. Note=Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (PubMed:31820781). Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (PubMed:20085810). {ECO:0000250|UniProtKB:Q91ZY8, ECO:0000269|PubMed:20085810, ECO:0000269|PubMed:31820781}.
uniprot
proteins