Q9QZ49
uniprot
Q9QZ49
canonical
amino_acid_sequence
MASRGVVGLFLLSALPLLCLELRRGIPSLGIKDLILLSGRIFLLLALLTLVISVTTSWFNSLKPSQGHLKEGEKENEKRRRLVRERQQEAQGEKASRYIENVLKPQQEMKLKKLEERFYQMTGETWKLTAGHRLLEGDEDSEFENSSQASFETINGEAARRQNLPKFSTEISPAARPLLRKEVPDLPEEPSETAEEVVTVALRCPNGRVLRRRFFKSWNSQVLLDWMMKVGYHKSLYRLSTSFPRRALEVEGGSSLEDIGITVDTVLNVEEKEQSSQ
uniprot
proteins
function
FUNCTION: Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
31555
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21949850
uniprot
proteins
pubmed
9931425
uniprot
proteins
sequence_length
277
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 2..22; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 34..54; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins