Slc22a21
entrez
56517
canonical
uniprot
Q9WTN6
canonical
ensembl
ENSMUSG00000063652
resolver
ensp
ENSMUSP00000075814
resolver
ensp
ENSMUSP00000300511
resolver
enst
ENSMUST00000076493
resolver
genesymbol
Slc22a21
resolver
genesymbol_syn
Octn3
resolver
genesymbol_syn
Slc22a9
resolver
uniprot
A2RSK7
resolver
uniprot
Q5SWV0
resolver
uniprot_entry
A2RSK7_MOUSE
resolver
uniprot_entry
S22AL_MOUSE
resolver
uniprot_sec
Q5SWV0
resolver
amino_acid_sequence
MLDYDEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTVNLSSAWRNHSIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAIITLFFPESSGVSLPETIDEMQKVKKLKQRQSLSKKGSPKESKGNVSRTSRTSEPKGF
uniprot
proteins
function
FUNCTION: Sodium-ion independent, medium affinity carnitine transporter. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 746. {ECO:0000269|PubMed:11010964}.
uniprot
proteins
mass_dalton
63321
uniprot
proteins
protein_family
Major facilitator (TC 2.A.1) superfamily
uniprot
proteins
protein_family
Organic cation transporter (TC 2.A.1.19) family
uniprot
proteins
pubmed
11010964
uniprot
proteins
pubmed
12535646
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16288981
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
564
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000269|PubMed:11010964, ECO:0000269|PubMed:12535646, ECO:0000269|PubMed:16288981}; Multi-pass membrane protein {ECO:0000269|PubMed:11010964, ECO:0000269|PubMed:12535646, ECO:0000269|PubMed:16288981}.
uniprot
proteins
transmembrane_region
TRANSMEM 21..41; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 143..163; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 173..193; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 198..218; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 233..253; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 345..365; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 377..397; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 410..430; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 434..454; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 466..486; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 492..512; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins