Cacng5
entrez
140726
canonical
uniprot
Q8VHW8
canonical
ensembl
ENSRNOG00000003288
resolver
ensembl
ENSRNOG00055028667
resolver
ensembl
ENSRNOG00060013726
resolver
ensembl
ENSRNOG00065018994
resolver
ensp
ENSRNOP00000004578
resolver
ensp
ENSRNOP00055040803
resolver
ensp
ENSRNOP00060018583
resolver
ensp
ENSRNOP00065025493
resolver
enst
ENSRNOT00000004578
resolver
enst
ENSRNOT00055049599
resolver
enst
ENSRNOT00060023426
resolver
enst
ENSRNOT00065031939
resolver
genesymbol
Cacng5
resolver
uniprot_entry
CCG5_RAT
resolver
amino_acid_sequence
MSTCGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILPQNQSTEVKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNSQMTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWIRGRSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC
uniprot
proteins
function
FUNCTION: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. According to PubMed:18817736, shows only specificity for GRIA2 and specifically to the form of GRIA2 for which a single amino acid in the pore region has been edited from a glutamine to an arginine residue. Thought to stabilize the calcium channel in an inactivated (closed) state. {ECO:0000269|PubMed:18817736, ECO:0000269|PubMed:19234459}.
uniprot
proteins
mass_dalton
30924
uniprot
proteins
protein_family
CACNG subfamily
uniprot
proteins
protein_family
PMP-22/EMP/MP20 family
uniprot
proteins
pubmed
11738816
uniprot
proteins
pubmed
18817736
uniprot
proteins
pubmed
19234459
uniprot
proteins
pubmed
19265014
uniprot
proteins
sequence_length
275
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Postsynaptic density membrane {ECO:0000269|PubMed:18817736}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 129..149; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 181..201; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins