Ndufa10
entrez
67273
canonical
uniprot
Q99LC3
canonical
ensembl
ENSMUSG00000026260
resolver
ensp
ENSMUSP00000027478
resolver
enst
ENSMUST00000027478
resolver
genesymbol
Ndufa10
resolver
uniprot
Q3UKK0
resolver
uniprot
Q8BL57
resolver
uniprot
Q9CW21
resolver
uniprot_entry
NDUAA_MOUSE
resolver
uniprot_sec
Q3UKK0
resolver
uniprot_sec
Q8BL57
resolver
uniprot_sec
Q9CW21
resolver
amino_acid_sequence
MALRLLRLVPASAPARGLAAGAQRVGRIHTSVHCKLRYGLLAAILGDKTTKKLHEYSRVITVDGNICSGKNKLAKEIAQQLGMKHYPEAGIQYSSTTTGDGRPLDIEFSGSCSLEKFYDDPKSNDGNSYRLQSWLYASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGYIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVPEVQSRIQKKGDPHEMKVTSAYLQDIENAYKKTFLPKMSEMCEVLVYDSWEAEDPTKVVEDIEYLKYNKGPWLKQDDWTFHYLRMLVQDKTEVLNYTTIPVYLPEITIGAHQGSRIYNSFRELPGRKYAPGYNAEVGDKWIWLK
uniprot
proteins
function
FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. {ECO:0000269|PubMed:24652937, ECO:0000269|PubMed:38575788}.
uniprot
proteins
mass_dalton
40603
uniprot
proteins
mutagenesis
MUTAGEN 250; /note="S->A: Leads to mitochondrial depolarization."; /evidence="ECO:0000269|PubMed:24652937"; MUTAGEN 250; /note="S->D: Phosphomimetic mutant; able to rescue mitochondrial depolarization in a Pink1 mutant background."; /evidence="ECO:0000269|PubMed:24652937
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Ser-250 by PINK1 is required for the binding and/or reduction of the complex I substrate ubiquinone. {ECO:0000269|PubMed:24652937}.; PTM: Acetylation of Lys-242 is observed in liver mitochondria from fasted mice but not from fed mice.
uniprot
proteins
protein_family
Complex I NDUFA10 subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24652937
uniprot
proteins
pubmed
38575788
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:38575788}.
uniprot
proteins