Dnajb1
entrez
81489
canonical
uniprot
Q9QYJ3
canonical
ensembl
ENSMUSG00000005483
resolver
ensp
ENSMUSP00000005620
resolver
ensp
ENSMUSP00000148685
resolver
enst
ENSMUST00000005620
resolver
enst
ENSMUST00000212300
resolver
genesymbol
Dnajb1
resolver
genesymbol_syn
Hsp40
resolver
genesymbol_syn
Hspf1
resolver
uniprot
A0A1D5RM96
resolver
uniprot
Q3TU79
resolver
uniprot
Q3TYL7
resolver
uniprot_entry
A0A1D5RM96_MOUSE
resolver
uniprot_entry
DNJB1_MOUSE
resolver
uniprot_entry
Q3TU79_MOUSE
resolver
uniprot_entry
Q3TYL7_MOUSE
resolver
amino_acid_sequence
MGKDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEGLKGGSPSGGSSGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGMDIDDTFSSFPMGMGGFTNMNFGRSRPSQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSRTILEQVLPI
uniprot
proteins
function
FUNCTION: Interacts with HSP70 and can stimulate its ATPase activity. Acts also with TTC1 as a chaperone adapter that regulates HSP70-dependent folding process by interacting with the HSP70 amino terminal region. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). {ECO:0000250|UniProtKB:P25685}.
uniprot
proteins
mass_dalton
38167
uniprot
proteins
pubmed
11092732
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
340
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P25685}. Nucleus {ECO:0000250|UniProtKB:P25685}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P25685}. Note=Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock. {ECO:0000250|UniProtKB:P25685}.
uniprot
proteins