Dcaf7
entrez
71833
canonical
uniprot
P61963
canonical
ensembl
ENSMUSG00000049354
resolver
ensp
ENSMUSP00000058168
resolver
enst
ENSMUST00000058438
resolver
genesymbol
Dcaf7
resolver
genesymbol_syn
Han11
resolver
genesymbol_syn
Wdr68
resolver
uniprot
O15491
resolver
uniprot
Q3TMV9
resolver
uniprot
Q80ZU1
resolver
uniprot
Q9DAE4
resolver
uniprot_entry
DCAF7_MOUSE
resolver
uniprot_entry
Q80ZU1_MOUSE
resolver
uniprot_sec
O15491
resolver
uniprot_sec
Q3TMV9
resolver
uniprot_sec
Q9DAE4
resolver
amino_acid_sequence
MSLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV
uniprot
proteins
function
FUNCTION: Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
38926
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
protein_family
WD repeat DCAF7 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16887337
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
342
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000250}. Note=Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm.
uniprot
proteins