Dync2i1
entrez
217935
canonical
uniprot
Q8C761
canonical
ensembl
ENSMUSG00000042050
resolver
ensp
ENSMUSP00000047334
resolver
ensp
ENSMUSP00000302572
resolver
enst
ENSMUST00000039349
resolver
genesymbol
Dync2i1
resolver
genesymbol_syn
Wdr60
resolver
uniprot
Q3UN53
resolver
uniprot
Q3UNM4
resolver
uniprot_entry
DC2I1_MOUSE
resolver
uniprot_entry
Q3UN53_MOUSE
resolver
uniprot_sec
Q3UNM4
resolver
amino_acid_sequence
MEPGKRRTKDDTWKADDLRKHLKVQSGSPKEEKKLREKKAHKDSESAAPEYREHKSRDPDREARHKEKTAERDLYTSTEHPRGERDRERHKERRKDAKDREKDKLKERHRDQEAEKAHSRGKDREREKDRRARKEEIRQSMAYHDLLSRDMRGRQMAEKVEKKASKIRTEERERRDEDSERIDEDRERRYRERKLQYGDSKEHPLSYWLYKEDGEKKHRKAKDADREKRLREKSSMREKRERHAREKGSSLSDREVEDRHREKRHKEGLHYDDERRRSHADKKERSSKEEHKKRELKELEKEDNDLEATGPDEYLPNLEDDFVDYEDDFEVCDGDDDSNNEHEAREKAEELPLAQKREIQEIQKAISAENERVGELSLKMFQKQGWTEYTKEPWTDANDSPSRTPVCGIFVDFATASHRQKSRSQALKQKTRSSKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQYNEDNVERDIQTEDIETREVWTQHPGEGTAVSGGSEEKDFSDVTVVPKIDTPRLANFLRAACQVVAVLLEEDRLAAGPSWIPRAQDKALNISDSSSQLNTSLPFLQSRKVSCLHASRVQRQTVVSVHDLPEKAFAPSLDSRHLLCVWDIWQPSGPQKVLICESKVTCCCFSPLKAFLLFAGTVHGSVVVWDLREDSRIHHYVRLSNCFWAFRTPTFSTDGILTSVNHRSPLQAIEPVATSAYKKQSFVLSPFSTQEEMAGLSFHIASLDETGVLNVWVVVELPKADISGSMSDLGLIPGGRIKLVHSTVIQLGNSLSHKDSELWGSTQTLSVKFLPSDPNHFVVGTDMGLISHSTRQDWRVSPRVFKPEQHGVRPIKVNVIDFSPFEETVFLAGCSDGSIRLHQLTSERPIMQWDNSTSGHAVTSLQWSPTRPAVFLVQDDASRIYVWDLLENDLGPVAQQPISPDKLVAMTIVGEPEKTSGSFVALVLARTSGTVDVQNLKRRWTTPAVDEHSQLRLLLQK
uniprot
proteins
function
FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I1 plays a major role in retrograde ciliary protein trafficking in cilia and flagella. Also requires to maintain a functional transition zone. {ECO:0000250|UniProtKB:Q8WVS4}.
uniprot
proteins
mass_dalton
115382
uniprot
proteins
protein_family
Dynein light intermediate chain family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
999
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000250|UniProtKB:Q8WVS4}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8WVS4}. Note=Located at the base of the primary cilium in serum-starved fibroblasts. {ECO:0000250|UniProtKB:Q8WVS4}.
uniprot
proteins