Sfxn1
entrez
14057
canonical
uniprot
Q99JR1
canonical
ensembl
ENSMUSG00000021474
resolver
ensp
ENSMUSP00000021930
resolver
ensp
ENSMUSP00000217705
resolver
ensp
ENSMUSP00000217716
resolver
enst
ENSMUST00000021930
resolver
genesymbol
Sfxn1
resolver
uniprot
Q3UB44
resolver
uniprot
Q9CZG4
resolver
uniprot_entry
SFXN1_MOUSE
resolver
uniprot_sec
Q3UB44
resolver
uniprot_sec
Q9CZG4
resolver
amino_acid_sequence
MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPRNILLTNEQLENARKVVHDYRQGIVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKRVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDELQASIQRTHPEIRRVYFNKGL
uniprot
proteins
function
FUNCTION: Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. May also transport other amino acids including alanine and cysteine. {ECO:0000250|UniProtKB:Q9H9B4}.
uniprot
proteins
mass_dalton
35649
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
11274051
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
322
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000305|PubMed:11274051}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 103..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 147..167; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 175..195; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 229..249; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 267..287; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins