Sdsl
entrez
360816
canonical
uniprot
A0A6N3IN21
canonical
ensembl
ENSRNOG00000001391
resolver
ensp
ENSRNOP00000001882
resolver
genesymbol
Sdsl
resolver
genesymbol_syn
Sdhl
resolver
genesymbol_syn
Stdhgr
resolver
uniprot
D3ZHV7
resolver
uniprot_entry
SDSL_RAT
resolver
uniprot_sec
D3ZHV7
resolver
activity_regulation
ACTIVITY REGULATION: Serine dehydratase activity is inhibited by manganese chloride, ferrous chloride, cobalt chloride, cupric chloride, nickel chloride and zinc chloride. Glutamate racemase activity is inhibited by manganese chloride, ferrous chloride, cupric chloride and zinc chloride. {ECO:0000269|PubMed:33079132}.
uniprot
proteins
amino_acid_sequence
MEGASAECVRAEPFHRVTPLLESWALSQVAGMPVFLKYENVQIAGSFKIRGIGHFCQQMAKRGCRHLVCSSGGNAGIAAAYSAQKLGIPVTIVLPESTSKQVVRRLEGEGAEVQLTGKVWDEANVRAQELATRDGWVNVSPFDHPLIWEGNASLVRELKESLRTPPGAVVLAVGGGGLLAGVVAGLLEVGWQHVPIVAMETRGAHSFNAALLAGRLVTLPDITSVARSLGAKTVAARTLECAKECEVLSEVVEDREAVRAVQRFLDDERMLVEPACGAALAAVYSGILGRLQTEGRLSPALDSVVVIVCGGNNISSQQLQELKTQLNCS
uniprot
proteins
ec_number
4.3.1.17
uniprot
proteins
ec_number
4.3.1.19
uniprot
proteins
ec_number
5.1.1.3
uniprot
proteins
function
FUNCTION: Catalyzes the pyridoxal-phosphate-dependent dehydrative deamination of L-threonine and L-serine to ammonia and alpha-ketobutyrate and pyruvate, respectively (PubMed:33079132). Also exhibits racemase activity towards L-glutamate and D-glutamate (PubMed:33079132). {ECO:0000269|PubMed:33079132}.
uniprot
proteins
mass_dalton
34953
uniprot
proteins
protein_family
Serine/threonine dehydratase family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
33079132
uniprot
proteins
sequence_length
329
uniprot
proteins