Foxo6
entrez
329934
canonical
uniprot
Q70KY4
canonical
ensembl
ENSMUSG00000052135
resolver
ensp
ENSMUSP00000099716
resolver
enst
ENSMUST00000102656
resolver
genesymbol
Foxo6
resolver
uniprot_entry
FOXO6_MOUSE
resolver
amino_acid_sequence
MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGSEDCGPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLHLPERSPDDSPPGAPVPGPLSASAKWAASPASHASDDYEAWADFRGSRRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGARCPGELPRLAELGGPLGLHGGGVAGLPDALLDGAQDAYGPRARAGTPSYFGSCKASAYGGGGGFGPPALGSLRRLPMQTIQENKQASFVQAAAPFRPGALPALLPPPPPAPRPGPLLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPAHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAGPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
uniprot
proteins
function
FUNCTION: Transcriptional activator. {ECO:0000269|PubMed:12857750}.
uniprot
proteins
mass_dalton
57595
uniprot
proteins
mutagenesis
MUTAGEN 26; /note="T->A: No IGF1-induced increase in cytoplasmic localization."; /evidence="ECO:0000269|PubMed:12857750"; MUTAGEN 184; /note="S->A: No IGF1-induced increase in cytoplasmic localization. Increased transactivation activity."; /evidence="ECO:0000269|PubMed:12857750
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Ser-184 is be important in regulating the transacriptional activity. {ECO:0000269|PubMed:12857750}.
uniprot
proteins
pubmed
12857750
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
559
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12857750}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089, ECO:0000269|PubMed:12857750}. Note=When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors.
uniprot
proteins