Mtfr1l
entrez
298549
canonical
uniprot
Q5XII9
canonical
ensembl
ENSRNOG00000016937
resolver
ensembl
ENSRNOG00055026578
resolver
ensembl
ENSRNOG00060031974
resolver
ensembl
ENSRNOG00065026946
resolver
ensp
ENSRNOP00000022908
resolver
ensp
ENSRNOP00055037642
resolver
ensp
ENSRNOP00060045898
resolver
ensp
ENSRNOP00065038180
resolver
enst
ENSRNOT00000022908
resolver
enst
ENSRNOT00055045911
resolver
enst
ENSRNOT00060055454
resolver
enst
ENSRNOT00065046553
resolver
genesymbol
Mtfr1l
resolver
genesymbol_syn
Fam54b
resolver
uniprot_entry
MFR1L_RAT
resolver
amino_acid_sequence
MEANVTIPIWQNKPHGAARSVVRRIGTNLPLKPCPRASFETLPNISDLCLKDVPPVPTLADIAWIAADEEETYARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAASASLTPDFLSSGSSNVSSPLPCFGSSFHSTTSFVISDITEETEVEVPELPTIPLLCSASPECCKSEHKTTCSSSEEDDCISLSKASSFADMMGILKDFHRIKQSQDLSRSLLKEEDPAVLISEVLRRKFALKEEDISRKGN
uniprot
proteins
function
FUNCTION: Mitochondrial protein required for adaptation of mitochondrial dynamics to metabolic changes. Regulates mitochondrial morphology at steady state and mediates AMPK-dependent stress-induced mitochondrial fragmentation via the control of OPA1 levels. {ECO:0000250|UniProtKB:Q9H019}.
uniprot
proteins
mass_dalton
31730
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by AMPK. Upon stress, phosphorylation by AMPK is sufficient to induce mitochondrial fragmentation. {ECO:0000250|UniProtKB:Q9H019}.
uniprot
proteins
protein_family
MTFR1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
289
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9H019}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9H019}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9H019}.
uniprot
proteins