DEGS2
entrez
123099
canonical
uniprot
Q6QHC5
canonical
ensembl
ENSG00000168350
resolver
ensp
ENSP00000307126
resolver
enst
ENST00000305631
resolver
genesymbol
DEGS2
resolver
genesymbol_syn
C14orf66
resolver
hgnc
HGNC:20113
resolver
uniprot
Q6P492
resolver
uniprot_entry
DEGS2_HUMAN
resolver
uniprot_sec
Q6P492
resolver
amino_acid_sequence
MGNSASRSDFEWVYTDQPHTQRRKEILAKYPAIKALMRPDPRLKWAVLVLVLVQMLACWLVRGLAWRWLLFWAYAFGGCVNHSLTLAIHDISHNAAFGTGRAARNRWLAVFANLPVGVPYAASFKKYHVDHHRYLGGDGLDVDVPTRLEGWFFCTPARKLLWLVLQPFFYSLRPLCVHPKAVTRMEVLNTLVQLAADLAIFALWGLKPVVYLLASSFLGLGLHPISGHFVAEHYMFLKGHETYSYYGPLNWITFNVGYHVEHHDFPSIPGYNLPLVRKIAPEYYDHLPQHHSWVKVLWDFVFEDSLGPYARVKRVYRLAKDGL
uniprot
proteins
ec_number
1.14.18.5
uniprot
proteins
ec_number
1.14.19.17
uniprot
proteins
function
FUNCTION: Bifunctional enzyme which acts both as a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase. {ECO:0000269|PubMed:15063729}.
uniprot
proteins
mass_dalton
37197
uniprot
proteins
pathway_participation
PATHWAY: Membrane lipid metabolism; sphingolipid biosynthesis.
uniprot
proteins
protein_family
DEGS subfamily
uniprot
proteins
protein_family
Fatty acid desaturase type 1 family
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
15063729
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8R2F2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8R2F2}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 210..231; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins