Hgf
entrez
15234
canonical
uniprot
Q08048
canonical
ensembl
ENSMUSG00000028864
resolver
ensp
ENSMUSP00000030683
resolver
ensp
ENSMUSP00000142517
resolver
ensp
ENSMUSP00000143424
resolver
ensp
ENSMUSP00000201664
resolver
genesymbol
Hgf
resolver
uniprot
O55027
resolver
uniprot
Q53WS5
resolver
uniprot
Q61662
resolver
uniprot
Q64007
resolver
uniprot
Q6LBE6
resolver
uniprot
Q8C9G5
resolver
uniprot_entry
HGF_MOUSE
resolver
uniprot_entry
Q8C9G5_MOUSE
resolver
uniprot_sec
O55027
resolver
uniprot_sec
Q53WS5
resolver
uniprot_sec
Q61662
resolver
uniprot_sec
Q64007
resolver
uniprot_sec
Q6LBE6
resolver
amino_acid_sequence
MMWGTKLLPVLLLQHVLLHLLLLHVAIPYAEGQKKRRNTLHEFKKSAKTTLTKEDPLLKIKTKKVNSADECANRCIRNRGFTFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEFDLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKTCAHSAVNETDVPMETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTQTTVGWMVSLKYRNKHICGGSLIKESWVLTARQCFPARNKDLKDYEAWLGIHDVHERGEEKRKQILNISQLVYGPEGSDLVLLKLARPAILDNFVSTIDLPSYGCTIPEKTTCSIYGWGYTGLINADGLLRVAHLYIMGNEKCSQHHQGKVTLNESELCAGAEKIGSGPCEGDYGGPLICEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKVILTYKL
uniprot
proteins
function
FUNCTION: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed:20624990). Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity). Activates MAPK signaling following TMPRSS13 cleavage and activation (By similarity). {ECO:0000250|UniProtKB:P14210, ECO:0000269|PubMed:20624990}.
uniprot
proteins
mass_dalton
82945
uniprot
proteins
post_translational_modification
PTM: The single-chain precursor undergoes proteolytic processing by TMPRSS13 resulting in an active two-chain form. The single-chain precursor undergoes proteolytic processing by HGFAC resulting in an active two-chain form. {ECO:0000250|UniProtKB:P14210}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
protein_family
Plasminogen subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17804794
uniprot
proteins
pubmed
1831975
uniprot
proteins
pubmed
20624990
uniprot
proteins
pubmed
2142751
uniprot
proteins
pubmed
2144630
uniprot
proteins
pubmed
7822318
uniprot
proteins
pubmed
8081873
uniprot
proteins
pubmed
8135822
uniprot
proteins
pubmed
8241272
uniprot
proteins
pubmed
9488442
uniprot
proteins
sequence_length
728
uniprot
proteins