Viral penetration via permeabilization of host membrane
uniprot_keyword
KW-1173
canonical
name
Viral penetration via permeabilization of host membrane
uniprot
synonym
Viral penetration via host membrane disruption by virus
uniprot
synonym
Viral penetration via perforation of host membrane by virus
uniprot
definition
Viral membrane-penetration protein, usually associated with the viral capsid or released through partial programmed disassembly of the capsid, that locally permeabilizes the bilayer of a host membrane to allow virion penetration into the cytoplasm. Viral membrane- penetration proteins often need to be activated, mostly through endosomal acidic pH or receptor binding to display their membrane penetrating activity. Non-enveloped viruses such as parvovirus, human reovirus, BDV, BTV, rotavirus, papillomavirus, Flock house virus permeabilize the host endosomal membrane to penetrate the host cytoplasm.
uniprot
keywords
is_obsolete
false
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keywords
ontology_id
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keywords