SULT1A4
entrez
445329
canonical
uniprot
P0DMN0
canonical
ensembl
ENSG00000213648
resolver
ensembl
ENSG00000261052
resolver
ensp
ENSP00000343645
resolver
ensp
ENSP00000353600
resolver
ensp
ENSP00000378570
resolver
ensp
ENSP00000541892
resolver
ensp
ENSP00000541893
resolver
ensp
ENSP00000541896
resolver
ensp
ENSP00000541897
resolver
ensp
ENSP00000541898
resolver
ensp
ENSP00000541899
resolver
ensp
ENSP00000541900
resolver
ensp
ENSP00000627158
resolver
enst
ENST00000338971
resolver
enst
ENST00000360423
resolver
enst
ENST00000395138
resolver
enst
ENST00000871833
resolver
enst
ENST00000871834
resolver
enst
ENST00000871837
resolver
enst
ENST00000871838
resolver
enst
ENST00000871839
resolver
enst
ENST00000871840
resolver
enst
ENST00000871841
resolver
enst
ENST00000957099
resolver
genesymbol
SULT1A4
resolver
hgnc
HGNC:30004
resolver
uniprot
B4DNV0
resolver
uniprot
O95603
resolver
uniprot
P50224
resolver
uniprot
Q1ET66
resolver
uniprot
Q6ZWJ5
resolver
uniprot_entry
ST1A4_HUMAN
resolver
uniprot_sec
B4DNV0
resolver
uniprot_sec
O95603
resolver
uniprot_sec
P50224
resolver
uniprot_sec
Q1ET66
resolver
uniprot_sec
Q6ZWJ5
resolver
amino_acid_sequence
MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL
uniprot
proteins
ec_number
2.8.2.1
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, (R)-adrenaline/epinephrine, (R)-noradrenaline/norepinephrine and serotonin) and phenolic and catechol drugs (PubMed:15358107, PubMed:29524394). Catalyzes the sulfation of T4 (L-thyroxine/3,5,3',5'-tetraiodothyronine), T3 (3,5,3'-triiodothyronine), rT3 (3,3',5'-triiodothyronine) and 3,3'-T2 (3,3'-diiodothyronine), with a substrate preference of 3,3'-T2 > rT3 > T3 > T4 (PubMed:10199779). {ECO:0000269|PubMed:10199779, ECO:0000269|PubMed:15358107, ECO:0000269|PubMed:29524394}.
uniprot
proteins
mass_dalton
34196
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
10199779
uniprot
proteins
pubmed
15358107
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
29524394
uniprot
proteins
sequence_length
295
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P0DMM9}.
uniprot
proteins