NT5M
entrez
56953
canonical
uniprot
Q9NPB1
canonical
ensembl
ENSG00000205309
resolver
ensp
ENSP00000373674
resolver
ensp
ENSP00000481269
resolver
ensp
ENSP00000549663
resolver
ensp
ENSP00000715158
resolver
enst
ENST00000389022
resolver
enst
ENST00000616989
resolver
genesymbol
NT5M
resolver
genesymbol_syn
DNT2
resolver
hgnc
HGNC:15769
resolver
uniprot
A0A087WXT5
resolver
uniprot
A6NCJ5
resolver
uniprot
Q2I378
resolver
uniprot_entry
A0A087WXT5_HUMAN
resolver
uniprot_entry
NT5M_HUMAN
resolver
uniprot_entry
Q2I378_HUMAN
resolver
uniprot_sec
A6NCJ5
resolver
amino_acid_sequence
MIRLGGWCARRLCSAAVPAGRRGAAGGLGLAGGRALRVLVDMDGVLADFEGGFLRKFRARFPDQPFIALEDRRGFWVSEQYGRLRPGLSEKAISIWESKNFFFELEPLPGAVEAVKEMASLQNTDVFICTSPIKMFKYCPYEKYAWVEKYFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAEPTPSWEHVLFTACHNQHLQLQPPRRRLHSWADDWKAILDSKRPC
uniprot
proteins
ec_number
3.1.3.-
uniprot
proteins
function
FUNCTION: Dephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates (PubMed:10899995, PubMed:16004879). Shows low activity toward dGMP and marginal activity toward dIMP (PubMed:10899995, PubMed:16004879). {ECO:0000269|PubMed:10899995, ECO:0000269|PubMed:16004879}.
uniprot
proteins
mass_dalton
25862
uniprot
proteins
mutagenesis
MUTAGEN 41; /note="D->N: Loss of activity."; /evidence="ECO:0000269|PubMed:16004879
uniprot
proteins
protein_family
5'(3')-deoxyribonucleotidase family
uniprot
proteins
pubmed
10899995
uniprot
proteins
pubmed
12352955
uniprot
proteins
pubmed
15044615
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16004879
uniprot
proteins
sequence_length
228
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:10899995}.
uniprot
proteins