GALP
entrez
85569
canonical
uniprot
Q9UBC7
canonical
ensembl
ENSG00000197487
resolver
ensp
ENSP00000349884
resolver
ensp
ENSP00000411521
resolver
genesymbol
GALP
resolver
hgnc
HGNC:24840
resolver
uniprot
A1KXL3
resolver
uniprot_entry
GALP_HUMAN
resolver
uniprot_sec
A1KXL3
resolver
amino_acid_sequence
MAPPSVPLVLLLVLLLSLAETPASAPAHRGRGGWTLNSAGYLLGPVLHLPQMGDQDGKRETALEILDLWKAIDGLPYSHPPQPSKRNVMETFAKPEIGDLGMLSMKIPKEEDVLKS
uniprot
proteins
function
FUNCTION: [Isoform 1]: Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion.; FUNCTION: [Isoform 2]: Exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. Exhibits antimicrobial activity against Gram-negative bacterias, inducing bacterial membrane blebbing (PubMed:23537644). {ECO:0000269|PubMed:23537644}.
uniprot
proteins
mass_dalton
12545
uniprot
proteins
protein_family
Galanin family
uniprot
proteins
pubmed
10601261
uniprot
proteins
pubmed
16954604
uniprot
proteins
pubmed
17535903
uniprot
proteins
pubmed
23537644
uniprot
proteins
sequence_length
116
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins