FGF16
entrez
8823
canonical
uniprot
O43320
canonical
ensembl
ENSG00000196468
resolver
ensp
ENSP00000399324
resolver
enst
ENST00000439435
resolver
genesymbol
FGF16
resolver
hgnc
HGNC:3672
resolver
uniprot_entry
FGF16_HUMAN
resolver
amino_acid_sequence
MAEVGGVFASLDWDLHGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFHYR
uniprot
proteins
disease_involvement
DISEASE: Metacarpal 4-5 fusion (MF4) [MIM:309630]: A rare congenital malformation of the hand characterized by the partial or complete fusion of the fourth and fifth metacarpals. The anomaly occurs as an isolated trait or part of a syndrome. {ECO:0000269|PubMed:23709756, ECO:0000269|PubMed:25333065}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. {ECO:0000269|PubMed:16597617}.
uniprot
proteins
mass_dalton
23759
uniprot
proteins
protein_family
Heparin-binding growth factors family
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
16597617
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20094046
uniprot
proteins
pubmed
23709756
uniprot
proteins
pubmed
25333065
uniprot
proteins
pubmed
9473496
uniprot
proteins
sequence_length
207
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:O54769}.
uniprot
proteins