NMD3
entrez
51068
canonical
uniprot
Q96D46
canonical
ensembl
ENSG00000169251
resolver
ensp
ENSP00000307525
resolver
ensp
ENSP00000417559
resolver
ensp
ENSP00000419004
resolver
ensp
ENSP00000548811
resolver
ensp
ENSP00000548813
resolver
ensp
ENSP00000587201
resolver
ensp
ENSP00000615591
resolver
ensp
ENSP00000615592
resolver
enst
ENST00000351193
resolver
enst
ENST00000460469
resolver
enst
ENST00000472947
resolver
enst
ENST00000878752
resolver
enst
ENST00000917142
resolver
enst
ENST00000945532
resolver
enst
ENST00000945533
resolver
genesymbol
NMD3
resolver
hgnc
HGNC:24250
resolver
uniprot
C9JA08
resolver
uniprot
D3DNM7
resolver
uniprot
Q9Y2Z6
resolver
uniprot_entry
C9JA08_HUMAN
resolver
uniprot_entry
NMD3_HUMAN
resolver
uniprot_sec
D3DNM7
resolver
uniprot_sec
Q9Y2Z6
resolver
amino_acid_sequence
MEYMAESTDRSPGHILCCECGVPISPNPANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSAIHLIDPNTLQVADIDGSTFWSHPFNSLCHPKQLEEFIVMECSIVQDIKRAAGAGMISKKHTLGEVWVQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARERENMDTDDERQYQDFLEDLEEDEAIRKNVNIYRDSAIPVESDTDDEGAPRISLAEMLEDLHISQDATGEEGASMLT
uniprot
proteins
function
FUNCTION: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit. {ECO:0000269|PubMed:12724356, ECO:0000269|PubMed:12773398}.
uniprot
proteins
mass_dalton
57603
uniprot
proteins
mutagenesis
MUTAGEN 405; /note="K->A: Reduces accumulation in the nucleus. Loss of nucleolar localization; when associated with A-406."; /evidence="ECO:0000269|PubMed:12773398"; MUTAGEN 406; /note="K->A: Reduces accumulation in the nucleus. Loss of nucleolar localization; when associated with A-405."; /evidence="ECO:0000269|PubMed:12773398"; MUTAGEN 480; /note="L->A: Reduces nuclear export."; /evidence="ECO:0000269|PubMed:12773398"; MUTAGEN 484; /note="L->A: Reduces nuclear export."; /evidence="ECO:0000269|PubMed:12724356, ECO:0000269|PubMed:12773398"; MUTAGEN 487; /note="L->A: Reduces nuclear export."; /evidence="ECO:0000269|PubMed:12724356, ECO:0000269|PubMed:12773398
uniprot
proteins
protein_family
NMD3 family
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
12724356
uniprot
proteins
pubmed
12773398
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
32669547
uniprot
proteins
sequence_length
503
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12724356, ECO:0000269|PubMed:12773398}. Nucleus {ECO:0000269|PubMed:12724356, ECO:0000269|PubMed:12773398}. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner. {ECO:0000269|PubMed:12724356, ECO:0000269|PubMed:12773398}.
uniprot
proteins