MAT2B
entrez
27430
canonical
uniprot
Q9NZL9
canonical
ensembl
ENSG00000038274
resolver
ensp
ENSP00000280969
resolver
ensp
ENSP00000325425
resolver
genesymbol
MAT2B
resolver
genesymbol_syn
TGR
resolver
hgnc
HGNC:6905
resolver
uniprot
A0A140VJP2
resolver
uniprot
B2R5Y6
resolver
uniprot
Q1WAI7
resolver
uniprot
Q27J92
resolver
uniprot
Q3LIE8
resolver
uniprot
Q567T7
resolver
uniprot
Q6NYC7
resolver
uniprot
Q9BS89
resolver
uniprot
Q9H3E1
resolver
uniprot
Q9UJ54
resolver
uniprot_entry
A0A140VJP2_HUMAN
resolver
uniprot_entry
MAT2B_HUMAN
resolver
uniprot_sec
B2R5Y6
resolver
uniprot_sec
Q1WAI7
resolver
uniprot_sec
Q27J92
resolver
uniprot_sec
Q3LIE8
resolver
uniprot_sec
Q567T7
resolver
uniprot_sec
Q6NYC7
resolver
uniprot_sec
Q9BS89
resolver
uniprot_sec
Q9H3E1
resolver
uniprot_sec
Q9UJ54
resolver
amino_acid_sequence
MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH
uniprot
proteins
function
FUNCTION: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511). {ECO:0000269|PubMed:10644686, ECO:0000269|PubMed:23189196, ECO:0000269|PubMed:23425511, ECO:0000269|PubMed:25075345}.
uniprot
proteins
mass_dalton
37552
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1. {ECO:0000269|PubMed:10644686, ECO:0000269|PubMed:23189196, ECO:0000269|PubMed:25075345}.
uniprot
proteins
protein_family
DTDP-4-dehydrorhamnose reductase family
uniprot
proteins
protein_family
MAT2B subfamily
uniprot
proteins
pubmed
10644686
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11337507
uniprot
proteins
pubmed
12671891
uniprot
proteins
pubmed
12880961
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23189196
uniprot
proteins
pubmed
23425511
uniprot
proteins
pubmed
25075345
uniprot
proteins
sequence_length
334
uniprot
proteins