Cep112
entrez
76380
canonical
uniprot
Q5PR68
canonical
ensembl
ENSMUSG00000020728
resolver
ensp
ENSMUSP00000050597
resolver
ensp
ENSMUSP00000102326
resolver
ensp
ENSMUSP00000102335
resolver
ensp
ENSMUSP00000114569
resolver
ensp
ENSMUSP00000114627
resolver
ensp
ENSMUSP00000138235
resolver
enst
ENSMUST00000106724
resolver
genesymbol
Cep112
resolver
genesymbol_syn
Ccdc46
resolver
uniprot
F6Z089
resolver
uniprot
Q3TV83
resolver
uniprot
Q80ZN6
resolver
uniprot
Q99JS4
resolver
uniprot
Q9D9T1
resolver
uniprot
Q9DAQ8
resolver
uniprot_entry
CE112_MOUSE
resolver
uniprot_entry
F6Z089_MOUSE
resolver
uniprot_entry
Q3TV83_MOUSE
resolver
uniprot_entry
Q9DAQ8_MOUSE
resolver
uniprot_sec
Q80ZN6
resolver
uniprot_sec
Q99JS4
resolver
uniprot_sec
Q9D9T1
resolver
amino_acid_sequence
METGSEEEKWEKLDAEFDHFVVDMKPFVLKLPHRSERQRCALWIRKLCEPSGTGAGLMGRKNRNLYAKLLLHMLRRGILEGPFTHRPEPGTLKTLPSYMSIYFDEPNQAQPKDSSPEKLPDWVRGELQTGEQRLSDSWQCSSGEDNTLVLAASDAHREQYTGKLRMRSHSVSPTYREDKQHITSKICEVHSKTSPISLDDSDIEVRLNSWNLGIENPRYLRQKPLPVSLMTPKGSLRKASSLHDDHFLSRMHEKELDMKTKMMEAKFSEEKLKLQQKHDAEVQKILERKNNELEELKILYKKKQTETEETIRKLEKKVQILIRDCQVIRETKENQITELKKICEQSTESLNNDWEKKLHNAVAEMEKDKFELQKHHTETIQELLEDTNVRLSKMEADYVVQMQSTNHMIKELEGRVQQLMGEAENSNLQRQKLTQEKLELERCYQITCNELQELKTRRNILHKEKEHLVNDYEQNVKLLKTKYDSDINLLRQEHALSTSKTSGVIEELEQNICQLKQQVQESELQRKQQVKDQENKFHMEKNHLKHTYEKKVHELQSELDKEKEDAQRKIHKFEEALKEKEEQLSRVTEVQRLQAQQADAALEEFKRQVEVNSEKVYGEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDAKQRYEQQIVELKLEHEQEKTHLLQQHSAEKDSLVRDHDREIENLEKQLRAANMEHENQIQESKKRDAQVIADMEAQVHKLREELISVNSQRKQQLIELGLLREEEKQRAAKDHETAVKKLKAESERVKMELKKTHAAETEMTLEKANSRLKQIEKEYTQKLAKSSQIIAELQTTISSLKEESSRQQLAAERRLQDVIQKFEDEKQQLIRDNDQAIKALQDELETRSHQVRSAEKKLHHKELEAQEQIMYIRQEYETKFKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQSRR
uniprot
proteins
function
FUNCTION: Recruits mRNAs essential for sperm development, such as CFAP61 and FSIP2 mRNAs, into phase-separated condensates, thereby regulating their translation through a mechanism of liquid-liquid phase separation. {ECO:0000269|PubMed:39349455}.
uniprot
proteins
mass_dalton
112676
uniprot
proteins
pubmed
11544199
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
39349455
uniprot
proteins
sequence_length
954
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8N8E3}. Nucleus {ECO:0000269|PubMed:39349455}. Cytoplasm {ECO:0000269|PubMed:39349455}. Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000269|PubMed:39349455}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:39349455}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:39349455}. Note=In spermatogonia and early spermatocytes, CEP112 has diffuse localization in both the cytoplasm and nucleus. As cells progress to the round spermatid stage, it begins to concentrate in distinct cytoplasmic foci. In elongating spermatids, these foci become more pronounced and localized primarily to the cytoplasm, often in close proximity to the developing acrosome and manchette. In mature spermatozoa, is localized to the neck region, atypical centrioles and the base of the axoneme. {ECO:0000269|PubMed:39349455}.
uniprot
proteins