Got2
entrez
25721
canonical
uniprot
P00507
canonical
ensembl
ENSRNOG00000011782
resolver
ensembl
ENSRNOG00055008989
resolver
ensembl
ENSRNOG00060013790
resolver
ensembl
ENSRNOG00065011935
resolver
ensp
ENSRNOP00000015956
resolver
ensp
ENSRNOP00055012162
resolver
ensp
ENSRNOP00060018725
resolver
ensp
ENSRNOP00065014836
resolver
enst
ENSRNOT00000015956
resolver
enst
ENSRNOT00055015203
resolver
enst
ENSRNOT00060023570
resolver
enst
ENSRNOT00065019394
resolver
genesymbol
Got2
resolver
genesymbol_syn
Maat
resolver
uniprot
Q64551
resolver
uniprot
Q9QV50
resolver
uniprot_entry
AATM_RAT
resolver
uniprot_sec
Q64551
resolver
uniprot_sec
Q9QV50
resolver
amino_acid_sequence
MALLHSGRVLSGMAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAGKNLDKEYLPIGGLADFCKASAELALGENSEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEMAAVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK
uniprot
proteins
ec_number
2.6.1.1
uniprot
proteins
ec_number
2.6.1.7
uniprot
proteins
function
FUNCTION: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids (By similarity). {ECO:0000250, ECO:0000269|PubMed:17442055}.
uniprot
proteins
mass_dalton
47314
uniprot
proteins
protein_family
Class-I pyridoxal-phosphate-dependent aminotransferase family
uniprot
proteins
pubmed
11962739
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17442055
uniprot
proteins
pubmed
3004464
uniprot
proteins
pubmed
3322287
uniprot
proteins
pubmed
7309704
uniprot
proteins
pubmed
7470110
uniprot
proteins
pubmed
7759512
uniprot
proteins
pubmed
8238519
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:11962739}. Cell membrane {ECO:0000269|PubMed:11962739}. Note=Located in the mitochondria of liver, pancreas, spleen, heart, pituitary gland and submandibular gland cells. In kidney, located in the mitochondria, on the cell surface of regions with protrusions in distal tubules, on the apical cell surface of protrusions along the microvilli in cortical collecting ducts, in condensing vacuoles, on the cell surface at cell boundaries of adjoining kidney cells and on the cell surface of endothelial cells lining capillaries in the glomerulus. Also located at the cell surface of endothelial cells lining arterioles and on the cell surface of lymphocytes.
uniprot
proteins