P30823
uniprot
P30823
canonical
amino_acid_sequence
MGCKNLLSLGQQMLRRKVVDCSREESRLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIMVSGFVKGSIENWQLTENKSSPLCGNNDTNVKYGEGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDTDSPLPGAFKYRGWEEAKYAVAVGSLCALSTSPLGSMFPMPRVIYAMAEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMARTTDELDQVDQNEMVSASESQTGFLPAAEKFSLKTILSPKNMEPSKFSGLIVNISAGLLAVLIITVCIVAVLGREALAEGTLWAVFVMTGSVLLCMLVTGIIWRQPESKTKLSFKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIAFAIYFGYGVWHSEEASLAAGQAKTPDSNLDQCK
uniprot
proteins
function
FUNCTION: High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. {ECO:0000250|UniProtKB:Q09143}.; FUNCTION: (Microbial infection) Acts as a receptor for the ecotropic murine retroviral leukemia virus. {ECO:0000269|PubMed:10196347}.
uniprot
proteins
mass_dalton
67267
uniprot
proteins
protein_family
Amino acid-polyamine-organocation (APC) superfamily
uniprot
proteins
protein_family
Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
uniprot
proteins
pubmed
10196347
uniprot
proteins
pubmed
8473910
uniprot
proteins
sequence_length
624
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q09143}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..57; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 62..82; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 163..183; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 192..212; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 242..262; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 283..302; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 333..353; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 380..400; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 404..424; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 488..508; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 522..546; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 555..575; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 580..600; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins