Defb4
entrez
56519
canonical
uniprot
P82019
canonical
ensembl
ENSMUSG00000059230
resolver
ensp
ENSMUSP00000079808
resolver
enst
ENSMUST00000081017
resolver
genesymbol
Defb4
resolver
genesymbol_syn
Bdef4
resolver
uniprot
Q499H9
resolver
uniprot_entry
DEFB4_MOUSE
resolver
uniprot_entry
Q499H9_MOUSE
resolver
amino_acid_sequence
MRIHYLLFTFLLVLLSPLAAFTQIINNPITCMTNGAICWGPCPTAFRQIGNCGHFKVRCCKIR
uniprot
proteins
function
FUNCTION: Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells (PubMed:20068036). {ECO:0000269|PubMed:20068036}.
uniprot
proteins
mass_dalton
7129
uniprot
proteins
protein_family
Beta-defensin family
uniprot
proteins
pubmed
10922379
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20068036
uniprot
proteins
sequence_length
63
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
uniprot
proteins