Gmds
entrez
218138
canonical
uniprot
Q8K0C9
canonical
ensembl
ENSMUSG00000038372
resolver
ensp
ENSMUSP00000036696
resolver
ensp
ENSMUSP00000301352
resolver
enst
ENSMUST00000041859
resolver
genesymbol
Gmds
resolver
uniprot_entry
GMDS_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by GDP-fucose. {ECO:0000250|UniProtKB:O60547}.
uniprot
proteins
amino_acid_sequence
MAQAPAKCPSYPGSGDGEMGKLRKVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAIKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFMHIGKTIVWEGKNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQGDCSKAQQKLNWKPRVAFDELVREMVQADVELMRTNPNA
uniprot
proteins
ec_number
4.2.1.47
uniprot
proteins
function
FUNCTION: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose. {ECO:0000250|UniProtKB:O60547}.
uniprot
proteins
mass_dalton
41985
uniprot
proteins
pathway_participation
PATHWAY: Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 1/2. {ECO:0000250|UniProtKB:O60547}.
uniprot
proteins
protein_family
6-dehydratase subfamily
uniprot
proteins
protein_family
GDP-mannose 4
uniprot
proteins
protein_family
NAD(P)-dependent epimerase/dehydratase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
372
uniprot
proteins