Adam3
entrez
11497
canonical
uniprot
F8VQ03
canonical
ensembl
ENSMUSG00000031553
resolver
ensp
ENSMUSP00000033958
resolver
ensp
ENSMUSP00000132651
resolver
enst
ENSMUST00000033958
resolver
enst
ENSMUST00000171438
resolver
genesymbol
Adam3
resolver
genesymbol_syn
Cyrn
resolver
genesymbol_syn
Cyrn1
resolver
uniprot
Q62287
resolver
uniprot
Q810R6
resolver
uniprot_entry
ADAM3_MOUSE
resolver
uniprot_entry
Q62287_MOUSE
resolver
uniprot_entry
Q810R6_MOUSE
resolver
amino_acid_sequence
MLPLFLVLSYLGQVIAAGKDVETPLLQITVPEKIDTNIQDAKEAETQVTYVVRIEGKAYTLQLEKQSFLHPLFGTYLRDKLGTLQPYFSLVKTHCFYQGHAAEIPVSTVTLSTCSGLRGLLQLENITYGIEPLESSATFEHILYEIKNNKIDYSPLKENFANSEQESQSYRILVKPEKGSNSTLTKRILRIKIIMDKAMFDHMGSEVGVATQKVVHIFGLINTMFSQLKMTVMLNSLEIWSEQDKIETNGDADEVLQRFLLWKSKEISQKAQDITYLLLYKDHPDYVGATYHGMACNPNFTAGIALHPKTLAVEGFAIVLSQLLGINLGLAYDDVYNCFCPGSTCIMNPSAIRSQGIKVFSSCSVDEFKQLASQPELDCLRNTSETEFVVQPQGGSYCGNHLLEVPEQCDCGPPETCTHKKCCNPKDCTLIDAAQCGTGPCCDKRTCTIAERGRLCRKSKDQCDFPEFCNGETEGCAPDTKAADLEPCNNETAYCFGGVCRDPDRQCTDLFGKYAKGPNYVCAQEVNLQNDKFGNCHGRCNYSAIFCGKAVCYWNFAEVIQTEKYDVQYTYLGGQVCVSAHLRSQTGTRDDTYVHDGTVCGSGQVCFRGDCLRVHVLRGTRECEADDKCQGHGICNNLNNCQCESGFAPPECDMTPSSPGGSMDDGFWLPFDKSTPLIFKRHGLKYKKVLLISFYILLPFLVVLAFMAVKRMIGKRLAKQNISKALEHKEEAFNRGSMNPGVVSGGNTDQNLMTVPGSFNSYAYHGNTDQNFMTVPGSFNSYSYHGNTDQNFMTVPGSFNSYSYQDVPYYRSIPEDGNDSQQ
uniprot
proteins
function
FUNCTION: Involved in fertilization by controlling sperm migration into the oviduct (PubMed:19339711). Promotes the binding of sperm to the oocyte zona pellucida (PubMed:32529245). {ECO:0000269|PubMed:19339711, ECO:0000269|PubMed:32529245}.
uniprot
proteins
mass_dalton
91444
uniprot
proteins
post_translational_modification
PTM: Initially synthesized as a 110-kDa precursor in round spermatids, and the precursor is then processed into a 42-kDa mature protein during the sperm transport into and/or once in the epididymis. {ECO:0000269|PubMed:15514464, ECO:0000269|PubMed:24501175}.
uniprot
proteins
pubmed
11439107
uniprot
proteins
pubmed
15514464
uniprot
proteins
pubmed
19339711
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20945367
uniprot
proteins
pubmed
23633567
uniprot
proteins
pubmed
24501175
uniprot
proteins
pubmed
32529245
uniprot
proteins
sequence_length
822
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15514464}; Single-pass membrane protein {ECO:0000255}. Note=Localized in round and elongating spermatids. Localized on the anterior part of the sperm head, and is removed during the acrosome reaction. {ECO:0000269|PubMed:15514464}.
uniprot
proteins
transmembrane_region
TRANSMEM 689..709; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins