Gk5
entrez
235533
canonical
uniprot
Q8BX05
canonical
ensembl
ENSMUSG00000041440
resolver
ensp
ENSMUSP00000082313
resolver
ensp
ENSMUSP00000112717
resolver
genesymbol
Gk5
resolver
uniprot
Q14B67
resolver
uniprot
Q3TK02
resolver
uniprot
Q3TSE0
resolver
uniprot
Q80VA9
resolver
uniprot_entry
GLPK5_MOUSE
resolver
uniprot_sec
Q14B67
resolver
uniprot_sec
Q3TK02
resolver
uniprot_sec
Q3TSE0
resolver
uniprot_sec
Q80VA9
resolver
amino_acid_sequence
MSGQQERAERQREELSASASPPSRFVLGLDVGSTVIRCHVYDQTARVRGSSAQKVENVYPQPGWVEIDPDSLWAQFVAVIKDAVKAAGVQMNQIVGLGISTQRATFITWNKKTGHHFHNFISWQDLRAAELVKSWNNSLIMKLLHGATRVLHFFSRSKVMLTVSRFNFSTQHATLRLTWILQNLSEVKRAVEEDNCCFGTIDTWLLYKLTKGSSYATDYSNASTTGFFDPYAMRWSRLITTMVSIPLSILPPVKDTSYNFGSVDEKIFGVPIPVVALVGDQQSAMFGECCFETGDVKLTMGTGTFLDINTGKNLQHVNGGFYPLIGWKIGQELVCLAEGNAGDTGTAIMWAQKLDLFTDAAETEKMALSLEDSEGVYFVPSFSGLQAPLNDPCACASFMGLKHSTNKYHLVRAILESIAFRNKQLYDMLQREIQIPVTNIRADGGVCNNAFVMQMTSDLINEKIDRPAHFDMSCLGAASLAGLAVGFWADKEELQKLRQSEMVFKPQKKWQEYEVNMENWVKAVKRSMNWYNKT
uniprot
proteins
ec_number
2.7.1.30
uniprot
proteins
function
FUNCTION: Skin-specific kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Involved in skin-specific regulation of sterol regulatory element-binding protein (SREBP) processing and lipid biosynthesis. {ECO:0000269|PubMed:28607088}.
uniprot
proteins
mass_dalton
59812
uniprot
proteins
mutagenesis
MUTAGEN 175..534; /note="Missing: In ENU mutant Toku; mutant animals show progressive hair loss and accumulation of dermal lipids."; /evidence="ECO:0000269|PubMed:28607088"; MUTAGEN 280; /note="D->N: Reduced glycerol kinase activity. Mutant mice exhibit hair loss similar to that observed in Toku homozygotes."; /evidence="ECO:0000269|PubMed:28607088"; MUTAGEN 443; /note="D->N: Reduced glycerol kinase activity."; /evidence="ECO:0000269|PubMed:28607088
uniprot
proteins
pathway_participation
PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. {ECO:0000269|PubMed:28607088}.
uniprot
proteins
protein_family
FGGY kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
28607088
uniprot
proteins
sequence_length
534
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:28607088}.
uniprot
proteins