Rhov
entrez
171581
canonical
uniprot
Q9Z1Y0
canonical
ensembl
ENSRNOG00000013380
resolver
ensembl
ENSRNOG00055002882
resolver
ensembl
ENSRNOG00060026256
resolver
ensembl
ENSRNOG00065023810
resolver
ensp
ENSRNOP00000018277
resolver
ensp
ENSRNOP00000103357
resolver
ensp
ENSRNOP00055003339
resolver
ensp
ENSRNOP00060037747
resolver
ensp
ENSRNOP00065033291
resolver
enst
ENSRNOT00000124375
resolver
enst
ENSRNOT00055004505
resolver
enst
ENSRNOT00060045464
resolver
enst
ENSRNOT00065040805
resolver
genesymbol
Rhov
resolver
uniprot
A0A0H2UHK9
resolver
uniprot
A0ABK0LG78
resolver
uniprot_entry
A0ABK0LG78_RAT
resolver
uniprot_entry
RHOV_RAT
resolver
uniprot_sec
A0A0H2UHK9
resolver
amino_acid_sequence
MPPRELSEAEPPPLPASTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPSRYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPEPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway. {ECO:0000269|PubMed:9778532}.
uniprot
proteins
mass_dalton
26165
uniprot
proteins
mutagenesis
MUTAGEN 40; /note="G->V: Constitutively GTP-bound and constitutively active."; /evidence="ECO:0000269|PubMed:15664990"; MUTAGEN 56; /note="Y->L: Increase in GDP/GTP cycling."; /evidence="ECO:0000269|PubMed:15664990"; MUTAGEN 226..228; /note="RCR->QCQ: Loss of subcellular location to plasma membrane, decreased association with endomembranes."; /evidence="ECO:0000269|PubMed:16641371"; MUTAGEN 226; /note="R->Q: Loss of subcellular location to plasma membrane."; /evidence="ECO:0000269|PubMed:16641371"; MUTAGEN 227; /note="C->S: No effect on subcellular location."; /evidence="ECO:0000269|PubMed:15664990"; MUTAGEN 228; /note="R->Q: Loss of subcellular location to plasma membrane."; /evidence="ECO:0000269|PubMed:16641371"; MUTAGEN 229; /note="W->Y: Loss of subcellular location to plasma and endosomal membrane."; /evidence="ECO:0000269|PubMed:16641371"; MUTAGEN 230..231; /note="KK->QQ: Loss of subcellular location to plasma membrane, decreased association with endomembranes."; /evidence="ECO:0000269|PubMed:16641371"; MUTAGEN 230; /note="K->Q: Loss of subcellular location to plasma membrane, decreased association with endomembranes."; /evidence="ECO:0000269|PubMed:16641371"; MUTAGEN 231; /note="K->Q: Loss of subcellular location to plasma membrane, decreased association with endomembranes."; /evidence="ECO:0000269|PubMed:16641371"; MUTAGEN 234; /note="C->S: Loss of subcellular location to plasma and endosomal membranes."; /evidence="ECO:0000269|PubMed:15664990
uniprot
proteins
protein_family
Rho family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15664990
uniprot
proteins
pubmed
16641371
uniprot
proteins
pubmed
9778532
uniprot
proteins
sequence_length
236
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15664990, ECO:0000269|PubMed:16641371}; Lipid-anchor {ECO:0000269|PubMed:15664990, ECO:0000269|PubMed:16641371}; Cytoplasmic side {ECO:0000269|PubMed:15664990, ECO:0000269|PubMed:16641371}. Endosome membrane {ECO:0000269|PubMed:15664990, ECO:0000269|PubMed:16641371}; Lipid-anchor {ECO:0000269|PubMed:15664990, ECO:0000269|PubMed:16641371}; Cytoplasmic side {ECO:0000269|PubMed:15664990, ECO:0000269|PubMed:16641371}. Note=Treatment with TNF activates endosomal but not plasma membrane RHOV. {ECO:0000269|PubMed:15664990, ECO:0000269|PubMed:16641371}.
uniprot
proteins