TRMT6
entrez
51605
canonical
uniprot
Q9UJA5
canonical
ensembl
ENSG00000089195
resolver
ensp
ENSP00000203001
resolver
ensp
ENSP00000392070
resolver
genesymbol
TRMT6
resolver
genesymbol_syn
KIAA1153
resolver
genesymbol_syn
TRM6
resolver
hgnc
HGNC:20900
resolver
uniprot
B4DUV6
resolver
uniprot
Q76P92
resolver
uniprot
Q9BQV5
resolver
uniprot
Q9ULR7
resolver
uniprot
Q9Y2Z8
resolver
uniprot_entry
TRM6_HUMAN
resolver
uniprot_sec
B4DUV6
resolver
uniprot_sec
Q76P92
resolver
uniprot_sec
Q9BQV5
resolver
uniprot_sec
Q9ULR7
resolver
uniprot_sec
Q9Y2Z8
resolver
amino_acid_sequence
MEGSGEQPGPQPQHPGDHRIRDGDFVVLKREDVFKAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFEVTSGGSLQPKKKREEPTAETKEAGTDNRNIVDDGKSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITVVKPSTRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMGGFGSIIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSAKMLSSEPKDSALVEESNGTLEEKQASEQENEDSMAEAPESNHPEDQETMETISQDPEHKGPKERGSKKDYIQEKQRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVAMDNLKADTSLKSNASTLESHETEEPAAKKRKCPESDS
uniprot
proteins
function
FUNCTION: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508). Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29072297, PubMed:29107537). {ECO:0000269|PubMed:16043508, ECO:0000269|PubMed:29072297, ECO:0000269|PubMed:29107537}.
uniprot
proteins
mass_dalton
55799
uniprot
proteins
protein_family
TRM6/GCD10 family
uniprot
proteins
pubmed
10574461
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16043508
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26470919
uniprot
proteins
pubmed
29072297
uniprot
proteins
pubmed
29107537
uniprot
proteins
sequence_length
497
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P41814}.
uniprot
proteins