CBX8
entrez
57332
canonical
uniprot
Q9HC52
canonical
ensembl
ENSG00000141570
resolver
ensp
ENSP00000269385
resolver
enst
ENST00000269385
resolver
genesymbol
CBX8
resolver
genesymbol_syn
PC3
resolver
genesymbol_syn
RC1
resolver
hgnc
HGNC:15962
resolver
uniprot
Q96H39
resolver
uniprot
Q9NR07
resolver
uniprot_entry
CBX8_HUMAN
resolver
uniprot_sec
Q96H39
resolver
uniprot_sec
Q9NR07
resolver
amino_acid_sequence
MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRAREGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGKFPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR
uniprot
proteins
function
FUNCTION: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. {ECO:0000269|PubMed:21282530}.
uniprot
proteins
mass_dalton
43396
uniprot
proteins
pubmed
10825164
uniprot
proteins
pubmed
11313972
uniprot
proteins
pubmed
12167701
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19636380
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21047797
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21282530
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
389
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21282530}.
uniprot
proteins