Ndufa13
entrez
67184
canonical
uniprot
Q9ERS2
canonical
ensembl
ENSMUSG00000036199
resolver
ensp
ENSMUSP00000105796
resolver
ensp
ENSMUSP00000309970
resolver
enst
ENSMUST00000110167
resolver
genesymbol
Ndufa13
resolver
genesymbol_syn
Grim19
resolver
uniprot
Q9DC98
resolver
uniprot
Q9DCA1
resolver
uniprot_entry
NDUAD_MOUSE
resolver
uniprot_sec
Q9DC98
resolver
uniprot_sec
Q9DCA1
resolver
amino_acid_sequence
MAASKVKQDMPPPGGYGPIDYKRNLPRRGLSGYSMFAVGIGALIFGYWRMMRWNQERRRLLIEDLEARIALMPLFQAEKDRRTLQILRENLEEEAIIMKDVPNWKVGESVFHTTRWVPPLIGEMYGLRTKEEMSNANFGFTWYT
uniprot
proteins
function
FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes. {ECO:0000269|PubMed:38575788}.
uniprot
proteins
mass_dalton
16860
uniprot
proteins
protein_family
Complex I NDUFA13 subunit family
uniprot
proteins
pubmed
10924506
uniprot
proteins
pubmed
12628925
uniprot
proteins
pubmed
12867595
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
38575788
uniprot
proteins
sequence_length
144
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:38575788, ECO:0000305|PubMed:12628925}; Single-pass membrane protein {ECO:0000269|PubMed:38575788, ECO:0000305|PubMed:12628925}; Matrix side {ECO:0000269|PubMed:38575788, ECO:0000305|PubMed:12628925}. Nucleus {ECO:0000269|PubMed:12628925}. Note=Localizes mainly in the mitochondrion. May be translocated into the nucleus upon IFN/RA treatment. {ECO:0000250|UniProtKB:Q9P0J0}.
uniprot
proteins
transmembrane_region
TRANSMEM 30..51; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins