Gja3
entrez
79217
canonical
uniprot
P29414
canonical
ensembl
ENSRNOG00000008847
resolver
ensp
ENSRNOP00000011699
resolver
ensp
ENSRNOP00000102347
resolver
enst
ENSRNOT00000011699
resolver
enst
ENSRNOT00000148468
resolver
genesymbol
Gja3
resolver
genesymbol_syn
Cxn-46
resolver
uniprot
G3V747
resolver
uniprot_entry
CXA3_RAT
resolver
uniprot_entry
G3V747_RAT
resolver
amino_acid_sequence
MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEEVWGDEQSDFTCNTQQPGCENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEELLRRDNPQHGRGREPMRTGSPRDPPLRDDRGKVRIAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFQLQPLYRCDRWPCPNTVDCFISRPTEKTIFVIFMLAVACASLVLNMLEIYHLGWKKLKQGVTNHFNPDASEVRHKPLDPLSEAANSGPPSVSIGLPPYYTHPACPTVQGKATGFPGAPLLPADFTVVTLNDAQGRGHPVKHCNGHHLTTEQNWASLGAEPQTPASKPSSAASSPHGRKGLTDSSGSSLEESALVVTPEGEQALATTVEMHSPPLVLLDPERSSKSSSGRARPGDLAI
uniprot
proteins
function
FUNCTION: Structural component of lens fiber gap junctions (Probable). Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (Probable). {ECO:0000250|UniProtKB:Q9TU17, ECO:0000305|PubMed:1659572}.
uniprot
proteins
mass_dalton
46013
uniprot
proteins
protein_family
Alpha-type (group II) subfamily
uniprot
proteins
protein_family
Connexin family
uniprot
proteins
pubmed
1659572
uniprot
proteins
sequence_length
416
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:1659572}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9TU17}. Cell junction, gap junction {ECO:0000250|UniProtKB:Q9TU17}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..40; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q9TU17"; TRANSMEM 72..92; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q9TU17"; TRANSMEM 159..179; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q9TU17"; TRANSMEM 208..228; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q9TU17
uniprot
proteins