Gcsh
entrez
68133
canonical
uniprot
Q91WK5
canonical
ensembl
ENSMUSG00000034424
resolver
ensp
ENSMUSP00000037131
resolver
enst
ENSMUST00000040484
resolver
genesymbol
Gcsh
resolver
uniprot
Q9CY75
resolver
uniprot
Q9D197
resolver
uniprot_entry
GCSH_MOUSE
resolver
uniprot_sec
Q9CY75
resolver
uniprot_sec
Q9D197
resolver
amino_acid_sequence
MSLQVSRSLRVVAYSLRTALTFCSPRPCVPSAAAVRSLRTGSALLSVRKFTEKHEWITTEEGIGTVGISNFAQEALGDVVYCSLPEVGTKLKKQEEFGALESVKAASELYSPLSGEVTEVNEALAENPGLVNKSCYEDGWLIKMTLSDPSEMDELMSEEAYEKYVKSIEE
uniprot
proteins
function
FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Has a pivotal role in the lipoylation of enzymes involved in cellular energetics such as the mitochondrial dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (DLAT), and the mitochondrial dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (DLST). {ECO:0000250|UniProtKB:P23434}.
uniprot
proteins
mass_dalton
18637
uniprot
proteins
protein_family
GcvH family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
170
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P23434}.
uniprot
proteins