Maob
entrez
25750
canonical
uniprot
P19643
canonical
ensembl
ENSRNOG00000029778
resolver
ensembl
ENSRNOG00055016304
resolver
ensembl
ENSRNOG00060018700
resolver
ensembl
ENSRNOG00065021133
resolver
ensp
ENSRNOP00000101104
resolver
ensp
ENSRNOP00055022193
resolver
ensp
ENSRNOP00060026318
resolver
ensp
ENSRNOP00065029013
resolver
enst
ENSRNOT00000164539
resolver
enst
ENSRNOT00055027658
resolver
enst
ENSRNOT00060032306
resolver
enst
ENSRNOT00065035977
resolver
genesymbol
Maob
resolver
uniprot
Q5EBB5
resolver
uniprot_entry
AOFB_RAT
resolver
uniprot_sec
Q5EBB5
resolver
amino_acid_sequence
MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNTFLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
uniprot
proteins
ec_number
1.4.3.21
uniprot
proteins
ec_number
1.4.3.4
uniprot
proteins
function
FUNCTION: Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:20493079). Preferentially degrades benzylamine and phenylethylamine (PubMed:20493079). {ECO:0000269|PubMed:20493079}.
uniprot
proteins
mass_dalton
58459
uniprot
proteins
mutagenesis
MUTAGEN 139; /note="L->H: No change in substrate affinity."; MUTAGEN 199; /note="I->F: Increased affinity for serotonin and tyramine."; /evidence="ECO:0000269|PubMed:9162023
uniprot
proteins
protein_family
Flavin monoamine oxidase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20493079
uniprot
proteins
pubmed
2974701
uniprot
proteins
pubmed
4156831
uniprot
proteins
pubmed
6428396
uniprot
proteins
pubmed
9162023
uniprot
proteins
sequence_length
520
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.
uniprot
proteins
transmembrane_region
TRANSMEM 490..516; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000250
uniprot
proteins