IMMP2L
entrez
83943
canonical
uniprot
Q96T52
canonical
ensembl
ENSG00000184903
resolver
ensp
ENSP00000329553
resolver
ensp
ENSP00000384966
resolver
ensp
ENSP00000388327
resolver
genesymbol
IMMP2L
resolver
hgnc
HGNC:14598
resolver
uniprot
A4D0S9
resolver
uniprot
Q75MF1
resolver
uniprot
Q75MN9
resolver
uniprot
Q75MP0
resolver
uniprot
Q75MS5
resolver
uniprot
Q75MS8
resolver
uniprot
Q96HJ2
resolver
uniprot_entry
A4D0S9_HUMAN
resolver
uniprot_entry
IMP2L_HUMAN
resolver
uniprot_sec
Q75MF1
resolver
uniprot_sec
Q75MN9
resolver
uniprot_sec
Q75MP0
resolver
uniprot_sec
Q75MS5
resolver
uniprot_sec
Q75MS8
resolver
uniprot_sec
Q96HJ2
resolver
amino_acid_sequence
MAQSQGWVKRYIKAFCKGFFVAVPVAVTFLDRVACVARVEGASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE
uniprot
proteins
disease_involvement
DISEASE: Gilles de la Tourette syndrome (GTS) [MIM:137580]: Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. {ECO:0000269|PubMed:11254443}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. {ECO:0000269|PubMed:15814844}.
uniprot
proteins
mass_dalton
19718
uniprot
proteins
protein_family
IMP2 subfamily
uniprot
proteins
protein_family
Peptidase S26 family
uniprot
proteins
pubmed
11254443
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15814844
uniprot
proteins
sequence_length
175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000305|PubMed:15814844}; Single-pass membrane protein {ECO:0000305|PubMed:15814844}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..37; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins