SERPINA3
entrez
12
canonical
uniprot
P01011
canonical
ensembl
ENSG00000196136
resolver
ensp
ENSP00000376793
resolver
ensp
ENSP00000560422
resolver
ensp
ENSP00000560423
resolver
ensp
ENSP00000560426
resolver
genesymbol
SERPINA3
resolver
genesymbol_syn
AACT
resolver
hgnc
HGNC:16
resolver
uniprot
B3KVQ7
resolver
uniprot
Q13703
resolver
uniprot
Q2TU87
resolver
uniprot
Q2TU88
resolver
uniprot
Q59GP9
resolver
uniprot
Q6LBY8
resolver
uniprot
Q6LDT7
resolver
uniprot
Q6NSC9
resolver
uniprot
Q8N177
resolver
uniprot
Q96DW8
resolver
uniprot
Q9UC47
resolver
uniprot
Q9UNU9
resolver
uniprot_entry
AACT_HUMAN
resolver
uniprot_sec
B3KVQ7
resolver
uniprot_sec
Q13703
resolver
uniprot_sec
Q2TU87
resolver
uniprot_sec
Q2TU88
resolver
uniprot_sec
Q59GP9
resolver
uniprot_sec
Q6LBY8
resolver
uniprot_sec
Q6LDT7
resolver
uniprot_sec
Q6NSC9
resolver
uniprot_sec
Q8N177
resolver
uniprot_sec
Q96DW8
resolver
uniprot_sec
Q9UC47
resolver
uniprot_sec
Q9UNU9
resolver
amino_acid_sequence
MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA
uniprot
proteins
function
FUNCTION: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. {ECO:0000269|PubMed:2404007}.
uniprot
proteins
mass_dalton
47651
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:23234360}.
uniprot
proteins
protein_family
Serpin family
uniprot
proteins
pubmed
10618372
uniprot
proteins
pubmed
11289720
uniprot
proteins
pubmed
12754519
uniprot
proteins
pubmed
1351206
uniprot
proteins
pubmed
14668352
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14760718
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15638460
uniprot
proteins
pubmed
1618300
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
2016749
uniprot
proteins
pubmed
23234360
uniprot
proteins
pubmed
2404007
uniprot
proteins
pubmed
2787670
uniprot
proteins
pubmed
3257719
uniprot
proteins
pubmed
6547997
uniprot
proteins
pubmed
6556193
uniprot
proteins
pubmed
6606438
uniprot
proteins
pubmed
6687683
uniprot
proteins
pubmed
7521171
uniprot
proteins
pubmed
8244391
uniprot
proteins
pubmed
8647626
uniprot
proteins
pubmed
8836107
uniprot
proteins
pubmed
9521649
uniprot
proteins
pubmed
9880565
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins