PBR
entrez
706
canonical
uniprot
P30536
canonical
ensembl
ENSG00000100300
resolver
ensp
ENSP00000328973
resolver
ensp
ENSP00000338004
resolver
ensp
ENSP00000379563
resolver
ensp
ENSP00000534389
resolver
ensp
ENSP00000534390
resolver
ensp
ENSP00000534391
resolver
ensp
ENSP00000534392
resolver
ensp
ENSP00000534393
resolver
ensp
ENSP00000534394
resolver
ensp
ENSP00000534396
resolver
ensp
ENSP00000534397
resolver
ensp
ENSP00000534398
resolver
ensp
ENSP00000534399
resolver
ensp
ENSP00000534400
resolver
ensp
ENSP00000534401
resolver
ensp
ENSP00000594394
resolver
ensp
ENSP00000642445
resolver
ensp
ENSP00000642446
resolver
ensp
ENSP00000642447
resolver
ensp
ENSP00000642448
resolver
enst
ENST00000329563
resolver
enst
ENST00000337554
resolver
enst
ENST00000396265
resolver
enst
ENST00000864330
resolver
enst
ENST00000864331
resolver
enst
ENST00000864332
resolver
enst
ENST00000864333
resolver
enst
ENST00000864334
resolver
enst
ENST00000864335
resolver
enst
ENST00000864337
resolver
enst
ENST00000864338
resolver
enst
ENST00000864339
resolver
enst
ENST00000864340
resolver
enst
ENST00000864341
resolver
enst
ENST00000864342
resolver
enst
ENST00000924335
resolver
enst
ENST00000972386
resolver
enst
ENST00000972387
resolver
enst
ENST00000972388
resolver
enst
ENST00000972389
resolver
genesymbol
PBR
resolver
genesymbol
TSPO
resolver
genesymbol_syn
BZRP
resolver
genesymbol_syn
MBR
resolver
hgnc
HGNC:1158
resolver
uniprot
O76068
resolver
uniprot
Q53Y59
resolver
uniprot
Q6ICF9
resolver
uniprot
Q96TF6
resolver
uniprot_entry
O76068_HUMAN
resolver
uniprot_entry
TSPO_HUMAN
resolver
uniprot_sec
Q53Y59
resolver
uniprot_sec
Q6ICF9
resolver
uniprot_sec
Q96TF6
resolver
amino_acid_sequence
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
uniprot
proteins
function
FUNCTION: Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678). {ECO:0000250, ECO:0000269|PubMed:1847678, ECO:0000269|PubMed:24814875}.
uniprot
proteins
mass_dalton
18828
uniprot
proteins
protein_family
TspO/BZRP family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
11215759
uniprot
proteins
pubmed
11304832
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16189298
uniprot
proteins
pubmed
16822554
uniprot
proteins
pubmed
17143515
uniprot
proteins
pubmed
1847678
uniprot
proteins
pubmed
19846611
uniprot
proteins
pubmed
20600583
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24814875
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
27641616
uniprot
proteins
pubmed
37047353
uniprot
proteins
pubmed
7721091
uniprot
proteins
pubmed
9915832
uniprot
proteins
sequence_length
169
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000269|PubMed:1847678}; Multi-pass membrane protein {ECO:0000269|PubMed:1847678}.
uniprot
proteins
transmembrane_region
TRANSMEM 6..26; /note="Helical; Name=1"; /evidence="ECO:0000250"; TRANSMEM 47..67; /note="Helical; Name=2"; /evidence="ECO:0000250"; TRANSMEM 80..100; /note="Helical; Name=3"; /evidence="ECO:0000250"; TRANSMEM 106..126; /note="Helical; Name=4"; /evidence="ECO:0000250"; TRANSMEM 135..155; /note="Helical; Name=5"; /evidence="ECO:0000250
uniprot
proteins