Tspan18
entrez
241556
canonical
uniprot
Q80WR1
canonical
ensembl
ENSMUSG00000027217
resolver
ensp
ENSMUSP00000028646
resolver
ensp
ENSMUSP00000106896
resolver
ensp
ENSMUSP00000287855
resolver
enst
ENSMUST00000028646
resolver
enst
ENSMUST00000111265
resolver
genesymbol
Tspan18
resolver
uniprot_entry
TSN18_MOUSE
resolver
amino_acid_sequence
MEGDCLSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYIVLAMGGLLFLLGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDTDVFSATWNSVMITFGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDGVVLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCLFRGIQ
uniprot
proteins
function
FUNCTION: Plays a role in the cell surface localization of ORAI1 and may participate in the regulation of Ca(2+) signaling and the VWF release in response to inflammatory stimuli. {ECO:0000269|PubMed:30573509}.
uniprot
proteins
mass_dalton
27801
uniprot
proteins
protein_family
Tetraspanin (TM4SF) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
30573509
uniprot
proteins
pubmed
32694189
uniprot
proteins
sequence_length
248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 14..34; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 50..70; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 84..104; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins