Armc3
entrez
70882
canonical
uniprot
A2AU72
canonical
ensembl
ENSMUSG00000037683
resolver
ensp
ENSMUSP00000048784
resolver
ensp
ENSMUSP00000110287
resolver
ensp
ENSMUSP00000304594
resolver
ensp
ENSMUSP00000304595
resolver
enst
ENSMUST00000049255
resolver
genesymbol
Armc3
resolver
uniprot
A2AU71
resolver
uniprot
B7ZN53
resolver
uniprot
Q8BY67
resolver
uniprot_entry
A2AU71_MOUSE
resolver
uniprot_entry
ARMC3_MOUSE
resolver
uniprot_entry
B7ZN53_MOUSE
resolver
uniprot_sec
Q8BY67
resolver
amino_acid_sequence
MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISALCENLSCKEFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKSDTSPPPSMEDKSSDVGYGRSISSSSSLRRGSKEKANAIFGSPTEEKSEPASVRNTILSRAFTKEKGVSKKKSRLQLICSSYLLWKGKGKKEEEKVKEEEEILALPKFTEGSPEKEWNPPPDPEFCVYVLEVTKSILPIVNLKEQIEVLAKYVADKMGGKIPKEKLADFSWELHISELKFQLKSNVVPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGMIGNLPPPEEYIVDLMFHPGNLLKLRSKEADLYRFL
uniprot
proteins
function
FUNCTION: Essential for male fertility and sperm motility. During spermatogenesis, promotes the autophagic degradation of excessive ribosomes, providing energy resources for mitochondria and thus ensuring sperm flagellar motility. {ECO:0000269|PubMed:34428398}.
uniprot
proteins
mass_dalton
97357
uniprot
proteins
mutagenesis
MUTAGEN 507; /note="C->A: Reduced level of palmitoylation and inability to rescue the autophagic flux in ARMC3-deficient embryonic fibrobalsts; when associated with A-518."; /evidence="ECO:0000269|PubMed:34428398"; MUTAGEN 518; /note="C->A: Reduced level of palmitoylation and inability to rescue the autophagic flux in ARMC3-deficient embryonic fibrobalsts; when associated with A-507."; /evidence="ECO:0000269|PubMed:34428398
uniprot
proteins
post_translational_modification
PTM: Palmitoylation is important for its function in autophagy. {ECO:0000269|PubMed:34428398}.
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
34428398
uniprot
proteins
pubmed
39704931
uniprot
proteins
sequence_length
881
uniprot
proteins