TAS2R38
entrez
5726
canonical
uniprot
P59533
canonical
ensembl
ENSG00000257138
resolver
ensp
ENSP00000448219
resolver
enst
ENST00000547270
resolver
genesymbol
TAS2R38
resolver
genesymbol_syn
PTC
resolver
hgnc
HGNC:9584
resolver
uniprot
A4D1U6
resolver
uniprot
P59552
resolver
uniprot
Q2M3E8
resolver
uniprot
Q645W3
resolver
uniprot
Q86UK3
resolver
uniprot_entry
T2R38_HUMAN
resolver
uniprot_sec
A4D1U6
resolver
uniprot_sec
P59552
resolver
uniprot_sec
Q2M3E8
resolver
uniprot_sec
Q645W3
resolver
uniprot_sec
Q86UK3
resolver
amino_acid_sequence
MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCLSISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLEAHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC
uniprot
proteins
function
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37892
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
11696554
uniprot
proteins
pubmed
12139982
uniprot
proteins
pubmed
12379855
uniprot
proteins
pubmed
12581520
uniprot
proteins
pubmed
12584440
uniprot
proteins
pubmed
12595690
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15496549
uniprot
proteins
pubmed
16720576
uniprot
proteins
sequence_length
333
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 56..76; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 95..115; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 143..163; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 191..211; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 252..272; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 277..297; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins