Ninl
entrez
78177
canonical
uniprot
Q6ZQ12
canonical
ensembl
ENSMUSG00000068115
resolver
ensp
ENSMUSP00000105522
resolver
ensp
ENSMUSP00000309174
resolver
ensp
ENSMUSP00000309180
resolver
genesymbol
Ninl
resolver
genesymbol_syn
Kiaa0980
resolver
genesymbol_syn
Nlp
resolver
uniprot
A2ANB8
resolver
uniprot
Q6NXH6
resolver
uniprot_entry
NINL_MOUSE
resolver
uniprot_sec
A2ANB8
resolver
uniprot_sec
Q6NXH6
resolver
amino_acid_sequence
MDNEEENHYVSRLRDVYSSCDTTGTGFLDQEELTQLCTKLGLEEQLPALLHILLGDDRLARVNFEEFKEGFVAVLSSGSGVEPSDEEGSSSESATSCAVPPKYMSGSKWYGRRSLPELGDSATATKYGSEQQAKGSVKPPLRRSASLESVESLKSDEDAESAKEPQNELFEAQGQLRSWGCEVFGTLRKSCSPSFSTPENLVQGIWHELGIGSSGHLNEQELAVVCRSIGLHSLEKQELEELFSKLDQDGDGRVSLAEFQLGLFGHEPPSLPASSSLIKPNRLWSHYQEESGCHTTTTSSLVSVCSGLRLFSSVDDGSGFAFPEQVISAWAQEGIQNGREILQSLDFSVDEKVNLLELTWALDNELLTVDGVIQQAALACYRQELSYHQGQVDQLVQERDKARQDLEKAEKRNLDFVREMDDCHSALEQLTEKKIKHLEQEYRGRLSLLRSEVEMERELFWEQARRQRAVLEQDVGRLQAEETSLREKLTLALKENSRLQKEIIEVVEKLSDSEKLVLRLQSDLQFVLKDKLEPQSMELLAQEEQFTAILNDYELKCRDLQDRNDELQAELEGLRLRLPRSRQSPAGTPGTHRRRIPGRGPADNLFVGESTPVSLETEIMVEQMKEHYQELRMQLETKVNYYEKEIEVMKRNFEKDKKEMEQAFQLEVSVLEGQKADLEALYAKSQEVILGLKEQLQDAAQSPEPAPAGLAHCCAQALCTLAQRLEVEMHLRHQDQLLQIRQEAEEELNQKLSWLEAQHAACCESLSLQHQCEKDQLLQTHLQRVKDLAAQLDLEKGRREEREQEVLAHCRRQQLKLQAVMSEEQARICRSFTLEKEKLEQTYREQVEGLVQEADVLRALLKNGTTVVSDQQERTPSSMSLGPDSRQQPTARQAVSPDGRTGAPAEWPGPEKAEGRDFPGQLCSIDAMPSPTPTLLSRRSSENLGVRDNHQRPLNAEEGAIPKEPEPSARTLTGQGQKLPLPVHPQMLEPSLGTTALDRKAASVGVQGQASEGPVGDGEGVQEAWLQFRGEATRMRPSLPCSELPNPQEATVMPAMSESEMKDVKIKLLQLEDVVRALEKADSRESYRAELQRLSEENLVLKSDLGKIQLELETSESKNEVQRQEIEVLKRDKEQACCDLEELSTQTQKYKDEMSQLNCRVLQLEGEPSGLHTQKEENHGAIQVLMKKLEEAGCREEQQGDQIQNLKIELERVNEECQYLRLSQAELTESLEESRSQLYSVQLRLEAAQSQHGRIVQRLQEQMSQLVPGARVAELQHLLNVKEEEARRLSAQQEEYRQQLKAREDQVEDAEARLRNVEWLLQEKVEELRKQFEKNTRSDLLLKELYVENAHLMKAVQLTEEKQRGAEKKNCVLEEKVRALNKLISKMAPASLSV
uniprot
proteins
function
FUNCTION: Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly (By similarity). Involved in vesicle transport in photoreceptor cells (By similarity). {ECO:0000250|UniProtKB:G9G127, ECO:0000250|UniProtKB:Q9Y2I6}.
uniprot
proteins
mass_dalton
157838
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PLK1 which disrupts its centrosome association and interaction with gamma-tubulin. {ECO:0000250|UniProtKB:Q9Y2I6}.; PTM: Ubiquitinated by the APC/C complex leading to its degradation. {ECO:0000250|UniProtKB:Q9Y2I6}.
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1394
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9Y2I6}. Cytoplasm {ECO:0000250|UniProtKB:Q9Y2I6}. Note=In interphase cells, NLP is transported to the centrosomes by the dynein-dynactin motor complex. During centrosome maturation, PLK1 directly phosphorylates NLP resulting in its release into the cytoplasm. {ECO:0000250|UniProtKB:Q9Y2I6}.
uniprot
proteins