Blvra
entrez
109778
canonical
uniprot
Q9CY64
canonical
ensembl
ENSMUSG00000001999
resolver
ensp
ENSMUSP00000002064
resolver
ensp
ENSMUSP00000292734
resolver
ensp
ENSMUSP00000350486
resolver
enst
ENSMUST00000002064
resolver
genesymbol
Blvra
resolver
uniprot
Q3T9C6
resolver
uniprot
Q80WR6
resolver
uniprot
Q9DD21
resolver
uniprot_entry
BIEA_MOUSE
resolver
uniprot_sec
Q3T9C6
resolver
uniprot_sec
Q80WR6
resolver
uniprot_sec
Q9DD21
resolver
amino_acid_sequence
MSTEPKRKFGVVVVGVGRAGSVRIRDLKDPHSSAFLNLIGYVSRRELGSLDNVRQISLEDALRSQEVDVAYICTESSSHEDYIRQFLQAGKHVLVEYPMALSFAAAQELWELAAQKGRVLHEEHIELLMEEFEFLKREVAGKELLKGSLRFTASPLEEEKFGFPAFSGISRLTWLVSLFGELSLISATMENRKEDQYMKMTVQLETQNKSPLSWIEEKGPGLKRNRHISIHFKSGSLEEVPNVGVNKNIFLKDQDIFIQKLLGQVSAEDLAAEKKRILHCLELASDIQRLCHRKQ
uniprot
proteins
ec_number
1.3.1.24
uniprot
proteins
function
FUNCTION: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Does not reduce bilirubin IXbeta (PubMed:29195835). Uses the reactants NADH or NADPH depending on the pH; NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7) (By similarity). NADPH, however, is the probable reactant in biological systems (By similarity). {ECO:0000250|UniProtKB:P53004, ECO:0000269|PubMed:29195835}.
uniprot
proteins
mass_dalton
33525
uniprot
proteins
pathway_participation
PATHWAY: Porphyrin-containing compound metabolism; protoheme degradation.
uniprot
proteins
protein_family
Biliverdin reductase subfamily
uniprot
proteins
protein_family
Gfo/Idh/MocA family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29195835
uniprot
proteins
pubmed
30657454
uniprot
proteins
sequence_length
295
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P53004}.
uniprot
proteins