CCNE2
entrez
9134
canonical
uniprot
O96020
canonical
ensembl
ENSG00000175305
resolver
ensp
ENSP00000309181
resolver
ensp
ENSP00000429089
resolver
ensp
ENSP00000530283
resolver
ensp
ENSP00000693544
resolver
genesymbol
CCNE2
resolver
hgnc
HGNC:1590
resolver
uniprot
O95439
resolver
uniprot_entry
CCNE2_HUMAN
resolver
uniprot_sec
O95439
resolver
amino_acid_sequence
MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
uniprot
proteins
function
FUNCTION: Essential for the control of the cell cycle at the late G1 and early S phase. {ECO:0000269|PubMed:9840927, ECO:0000269|PubMed:9840943, ECO:0000269|PubMed:9858585}.
uniprot
proteins
mass_dalton
46757
uniprot
proteins
mutagenesis
MUTAGEN 392; /note="T->A: Increase of steady state level."; /evidence="ECO:0000269|PubMed:9840943
uniprot
proteins
post_translational_modification
PTM: Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway. {ECO:0000269|PubMed:9858585}.; PTM: Lactylated at Lys-348 (PubMed:36896611). Delactylated by SIRT3 (PubMed:36896611). {ECO:0000269|PubMed:36896611}.
uniprot
proteins
protein_family
Cyclin E subfamily
uniprot
proteins
protein_family
Cyclin family
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
36896611
uniprot
proteins
pubmed
9840927
uniprot
proteins
pubmed
9840943
uniprot
proteins
pubmed
9858585
uniprot
proteins
sequence_length
404
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9840943}.
uniprot
proteins