Prdm15
entrez
114604
canonical
uniprot
E9Q8T2
canonical
ensembl
ENSMUSG00000014039
resolver
ensp
ENSMUSP00000093533
resolver
ensp
ENSMUSP00000113791
resolver
ensp
ENSMUSP00000312384
resolver
ensp
ENSMUSP00000312385
resolver
ensp
ENSMUSP00000312386
resolver
ensp
ENSMUSP00000312387
resolver
ensp
ENSMUSP00000312392
resolver
ensp
ENSMUSP00000312393
resolver
ensp
ENSMUSP00000312394
resolver
genesymbol
Prdm15
resolver
uniprot
E9Q6A1
resolver
uniprot
Q3UML7
resolver
uniprot_entry
PRD15_MOUSE
resolver
uniprot_sec
E9Q6A1
resolver
uniprot_sec
Q3UML7
resolver
amino_acid_sequence
MCPPTIWEKGGQVGARWSLRAPEVSAMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSKDIPAGTELRVWYAAFYAKKMDKPMLKQACSSVQAAGTPEPSVSVEPERGQWVCKVCSNTFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDAPRMEPPTAAESKSIQSVMVTKEPKKKPRRGRKPKASKVEQPLVIIKDKEPSEHVAEIITEIPPDEPVSATPDERIMELVLGKLAAPTNEASSVPKFPHHPSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTAPSSSVGLTNITVTPITTAAGTQFTNLQPVAVGHLTNPDRQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEATNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming. Involved in early embryo development. {ECO:0000269|PubMed:28740264}.
uniprot
proteins
mass_dalton
132870
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
28740264
uniprot
proteins
sequence_length
1174
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:28740264}.
uniprot
proteins