Fbxl12
entrez
30843
canonical
uniprot
Q9EPX5
canonical
ensembl
ENSMUSG00000066892
resolver
ensp
ENSMUSP00000083649
resolver
ensp
ENSMUSP00000083650
resolver
ensp
ENSMUSP00000114466
resolver
ensp
ENSMUSP00000115058
resolver
ensp
ENSMUSP00000119124
resolver
ensp
ENSMUSP00000121429
resolver
enst
ENSMUST00000086458
resolver
enst
ENSMUST00000086459
resolver
enst
ENSMUST00000131128
resolver
enst
ENSMUST00000140702
resolver
enst
ENSMUST00000148631
resolver
enst
ENSMUST00000151861
resolver
genesymbol
Fbxl12
resolver
genesymbol_syn
Fbl12
resolver
uniprot
A0A0R4J1Q8
resolver
uniprot
A0A0R4J1W2
resolver
uniprot
Q3UVH7
resolver
uniprot
Q8CDX0
resolver
uniprot
Q9CY04
resolver
uniprot
Q9QZN5
resolver
uniprot_entry
A0A0R4J1Q8_MOUSE
resolver
uniprot_entry
A0A0R4J1W2_MOUSE
resolver
uniprot_entry
FXL12_MOUSE
resolver
uniprot_sec
Q3UVH7
resolver
uniprot_sec
Q8CDX0
resolver
uniprot_sec
Q9CY04
resolver
uniprot_sec
Q9QZN5
resolver
amino_acid_sequence
MATLFDLPDLVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLLRRYMASRLYSLRMGGYLFSGSQAPQLSPALMRALGQKCPNLKRLCLHVADLSMVPITSLPSTLRTLELHSCEISMIWLQKEQDPTVLPLLECIVLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDASLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVGGLSAQGLVFLEGMPVLESLCFQGPLITPDMPTPTQIVSSCLTMPKLRVLEVQGLGWEGQEAEKILCKGLPHCIVIVRACPKESMDWWM
uniprot
proteins
function
FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37231
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
10531037
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
326
uniprot
proteins