DOK6
entrez
220164
canonical
uniprot
Q6PKX4
canonical
ensembl
ENSG00000206052
resolver
ensp
ENSP00000372160
resolver
enst
ENST00000382713
resolver
genesymbol
DOK6
resolver
genesymbol_syn
DOK5L
resolver
hgnc
HGNC:28301
resolver
uniprot
A6NNG3
resolver
uniprot
Q4V9S3
resolver
uniprot
Q8WUZ8
resolver
uniprot
Q96HI2
resolver
uniprot
Q96LU2
resolver
uniprot_entry
DOK6_HUMAN
resolver
uniprot_sec
A6NNG3
resolver
uniprot_sec
Q4V9S3
resolver
uniprot_sec
Q8WUZ8
resolver
uniprot_sec
Q96HI2
resolver
uniprot_sec
Q96LU2
resolver
amino_acid_sequence
MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVTELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDISLGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGFSYSSSLIQ
uniprot
proteins
function
FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. {ECO:0000269|PubMed:15286081}.
uniprot
proteins
mass_dalton
38318
uniprot
proteins
post_translational_modification
PTM: On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase. {ECO:0000269|PubMed:15286081}.
uniprot
proteins
protein_family
DOK family
uniprot
proteins
protein_family
Type B subfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15286081
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16177791
uniprot
proteins
sequence_length
331
uniprot
proteins