HAUS6
entrez
54801
canonical
uniprot
Q7Z4H7
canonical
ensembl
ENSG00000147874
resolver
ensp
ENSP00000369865
resolver
ensp
ENSP00000369871
resolver
ensp
ENSP00000678685
resolver
genesymbol
HAUS6
resolver
genesymbol_syn
DGT6
resolver
genesymbol_syn
FAM29A
resolver
genesymbol_syn
KIAA1574
resolver
hgnc
HGNC:25948
resolver
uniprot
B3KPK4
resolver
uniprot
B4DX82
resolver
uniprot
Q05CG1
resolver
uniprot
Q14CB6
resolver
uniprot
Q14CD9
resolver
uniprot
Q2TA91
resolver
uniprot
Q6IQ10
resolver
uniprot
Q6NZX5
resolver
uniprot
Q8IZQ4
resolver
uniprot
Q96FN0
resolver
uniprot
Q9H950
resolver
uniprot
Q9H998
resolver
uniprot
Q9HCJ8
resolver
uniprot
Q9NXT8
resolver
uniprot_entry
HAUS6_HUMAN
resolver
uniprot_sec
B3KPK4
resolver
uniprot_sec
B4DX82
resolver
uniprot_sec
Q05CG1
resolver
uniprot_sec
Q14CB6
resolver
uniprot_sec
Q14CD9
resolver
uniprot_sec
Q2TA91
resolver
uniprot_sec
Q6IQ10
resolver
uniprot_sec
Q6NZX5
resolver
uniprot_sec
Q8IZQ4
resolver
uniprot_sec
Q96FN0
resolver
uniprot_sec
Q9H950
resolver
uniprot_sec
Q9H998
resolver
uniprot_sec
Q9HCJ8
resolver
uniprot_sec
Q9NXT8
resolver
amino_acid_sequence
MSSASVTAFEKEHLWMYLQALGFEPGPATIACGKIVSHTHLGVNMFDKLNRDAFHIISYFLFQVLDQSLTKEVFKFCWPPFDQKSDTEFRKHCCEWIKRISGECGSSFPQVVGSLFLSPGGPKFIHLMYHFARFVAMKYIKSNSKNSSHHFVETFNIKPQDLHKCIARCHFARSRFLQILQRQDCVTQKYQENAQLSVKQVRNLRSECIGLENQIKKMEPYDDHSNMEEKIQKVRSLWASVNETLMFLEKEREVVSSVLSLVNQYALDGTNVAINIPRLLLDKIEKQMFQLHIGNVYEAGKLNLLTVIQLLNEVLKVMKYERCQADQARLTVDLHYLEKETKFQKERLSDLKHMRYRIKDDLTTIRHSVVEKQGEWHKKWKEFLGLSPFSLIKGWTPSVDLLPPMSPLSFDPASEEVYAKSILCQYPASLPDAHKQHNQENGCRGDSDTLGALHDLANSPASFLSQSVSSSDRNSVTVLEKDTKMGTPKEKNEAISKKIPEFEVENSPLSDVAKNTESSAFGGSLPAKKSDPFQKEQDHLVEEVARAVLSDSPQLSEGKEIKLEELIDSLGSNPFLTRNQIPRTPENLITEIRSSWRKAIEMEENRTKEPIQMDAEHREVLPESLPVLHNQREFSMADFLLETTVSDFGQSHLTEEKVISDCECVPQKHVLTSHIDEPPTQNQSDLLNKKVICKQDLECLAFTKLSETSRMETFSPAVGNRIDVMGGSEEEFMKILDHLEVSCNKPSTNKTMLWNSFQISSGISSKSFKDNDFGILHETLPEEVGHLSFNSSSSSEANFKLEPNSPMHGGTLLEDVVGGRQTTPESDFNLQALRSRYEALKKSLSKKREESYLSNSQTPERHKPELSPTPQNVQTDDTLNFLDTCDLHTEHIKPSLRTSIGERKRSLSPLIKFSPVEQRLRTTIACSLGELPNLKEEDILNKSLDAKEPPSDLTR
uniprot
proteins
function
FUNCTION: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin. {ECO:0000269|PubMed:19029337, ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.
uniprot
proteins
mass_dalton
108621
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis. {ECO:0000269|PubMed:19029337}.
uniprot
proteins
protein_family
HAUS6 family
uniprot
proteins
pubmed
10997877
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18443220
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19029337
uniprot
proteins
pubmed
19369198
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19427217
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
30723163
uniprot
proteins
sequence_length
955
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18443220, ECO:0000269|PubMed:19029337}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:19029337, ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}.
uniprot
proteins