Rbm5
entrez
300996
canonical
uniprot
B2GV05
canonical
ensembl
ENSRNOG00000018153
resolver
ensembl
ENSRNOG00055013482
resolver
ensembl
ENSRNOG00060029517
resolver
ensembl
ENSRNOG00065008425
resolver
ensp
ENSRNOP00000024529
resolver
ensp
ENSRNOP00055018780
resolver
ensp
ENSRNOP00060042837
resolver
ensp
ENSRNOP00065009899
resolver
enst
ENSRNOT00000024529
resolver
enst
ENSRNOT00055023141
resolver
enst
ENSRNOT00060051503
resolver
enst
ENSRNOT00065013371
resolver
genesymbol
Rbm5
resolver
uniprot_entry
RBM5_RAT
resolver
amino_acid_sequence
MGSDKRVSRTERSGRYGSIIDRDDRDERESRSRRRDSDYKRSSDDRRGDRYDDYRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERESKTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESVQSVDYYCDTIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLPDGNRVSAFSVASTAIAAAQWSSTQSQSGEGGNVDYSYMQPGQDGYTQYTQYSQDYQQFYQQQTGGLESDASATSGTTVTTTSAAVVSQSPQLYNQTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGTKYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSNQQAGLPSTKEGKEKKEKPKSKTAQQIAKDMERWAKSLNKQKENFKNSFQPVNSLREEERRESAAADAGFALFEKKGALAERQQLIPELVRNGDEENPLKRGLVAAYSGDSDNEEELVERLESEEEKLADWKKMACLLCRRQFPNRDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAGTVNYEQPTKDGIDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME
uniprot
proteins
function
FUNCTION: Component of the spliceosome A complex. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3' (By similarity). Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes production of a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes production of a catalytically active form of CASP2/Caspase-2 that induces apoptosis (By similarity). {ECO:0000250|UniProtKB:P52756}.
uniprot
proteins
mass_dalton
92352
uniprot
proteins
protein_family
RBM5/RBM10 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
815
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins