BORCS5
entrez
118426
canonical
uniprot
Q969J3
canonical
ensembl
ENSG00000165714
resolver
ensembl
ENSG00000280689
resolver
ensp
ENSP00000298571
resolver
ensp
ENSP00000321546
resolver
ensp
ENSP00000443023
resolver
ensp
ENSP00000485829
resolver
ensp
ENSP00000795395
resolver
enst
ENST00000542728
resolver
enst
ENST00000625206
resolver
genesymbol
BORCS5
resolver
genesymbol_syn
LOH12CR1
resolver
hgnc
HGNC:17950
resolver
uniprot
G3V1P3
resolver
uniprot
Q96QS5
resolver
uniprot_entry
BORC5_HUMAN
resolver
uniprot_entry
G3V1P3_HUMAN
resolver
uniprot_sec
Q96QS5
resolver
amino_acid_sequence
MGSEQSSEAESRPNDLNSSVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFSFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLLDRLNSMLPEGERLEPFSMKPDRELRL
uniprot
proteins
function
FUNCTION: As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility. {ECO:0000269|PubMed:25898167}.
uniprot
proteins
mass_dalton
22222
uniprot
proteins
mutagenesis
MUTAGEN 2; /note="G->A: Loss of myristoylation and loss of localization to lysosomal membranes."; /evidence="ECO:0000269|PubMed:25898167
uniprot
proteins
post_translational_modification
PTM: Myristoylation at Gly-2 mediates attachment to lysosome membranes. {ECO:0000269|PubMed:25898167}.
uniprot
proteins
protein_family
BORCS5 family
uniprot
proteins
pubmed
11896457
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25807930
uniprot
proteins
pubmed
25898167
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
196
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000269|PubMed:25898167}; Lipid-anchor {ECO:0000269|PubMed:25898167}; Cytoplasmic side {ECO:0000269|PubMed:25898167}.
uniprot
proteins