PGD
entrez
5226
canonical
uniprot
P52209
canonical
ensembl
ENSG00000142657
resolver
ensp
ENSP00000270776
resolver
ensp
ENSP00000627191
resolver
genesymbol
PGD
resolver
genesymbol_syn
PGDH
resolver
hgnc
HGNC:8891
resolver
uniprot
A8K2Y9
resolver
uniprot
B4DQJ8
resolver
uniprot
B4E2U0
resolver
uniprot
Q9BWD8
resolver
uniprot_entry
6PGD_HUMAN
resolver
uniprot_entry
B4E2U0_HUMAN
resolver
uniprot_sec
A8K2Y9
resolver
uniprot_sec
B4DQJ8
resolver
uniprot_sec
Q9BWD8
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by (2R)-3-phosphoglycerate. {ECO:0000269|PubMed:23153533}.
uniprot
proteins
amino_acid_sequence
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA
uniprot
proteins
ec_number
1.1.1.44
uniprot
proteins
function
FUNCTION: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. {ECO:0000269|PubMed:23153533, ECO:0000269|PubMed:3965621}.
uniprot
proteins
mass_dalton
53140
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.
uniprot
proteins
protein_family
6-phosphogluconate dehydrogenase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23153533
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
3965621
uniprot
proteins
pubmed
8978909
uniprot
proteins
sequence_length
483
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P85968}.
uniprot
proteins