PHPT1
entrez
29085
canonical
uniprot
Q9NRX4
canonical
ensembl
ENSG00000054148
resolver
ensp
ENSP00000247665
resolver
ensp
ENSP00000360724
resolver
genesymbol
HEL-S-132P
resolver
genesymbol
PHPT1
resolver
genesymbol_syn
PHP14
resolver
hgnc
HGNC:30033
resolver
uniprot
B1AMX0
resolver
uniprot
B1AMX1
resolver
uniprot
Q9H0Y3
resolver
uniprot
V9HWC4
resolver
uniprot_entry
PHP14_HUMAN
resolver
uniprot_entry
V9HWC4_HUMAN
resolver
uniprot_sec
B1AMX0
resolver
uniprot_sec
B1AMX1
resolver
uniprot_sec
Q9H0Y3
resolver
amino_acid_sequence
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY
uniprot
proteins
ec_number
3.9.1.3
uniprot
proteins
function
FUNCTION: Exhibits phosphohistidine phosphatase activity. {ECO:0000269|PubMed:19836471, ECO:0000269|PubMed:25574816}.
uniprot
proteins
mass_dalton
13833
uniprot
proteins
mutagenesis
MUTAGEN 21; /note="K->A: Decreased affinity for substrate and strongly reduced catalytic activity."; /evidence="ECO:0000269|PubMed:18991813"; MUTAGEN 45; /note="R->A: Slightly decreased affinity for substrate, but no effect on catalytic activity."; /evidence="ECO:0000269|PubMed:16219293, ECO:0000269|PubMed:18991813"; MUTAGEN 53; /note="H->A: Loss of activity."; /evidence="ECO:0000269|PubMed:16219293, ECO:0000269|PubMed:18991813"; MUTAGEN 78; /note="R->A: Decreased affinity for substrate and reduced catalytic activity."; /evidence="ECO:0000269|PubMed:16219293, ECO:0000269|PubMed:18991813"; MUTAGEN 94; /note="S->A: Decreased affinity for substrate and strongly reduced catalytic activity."; MUTAGEN 102; /note="H->A: Decreased affinity for substrate and slightly reduced catalytic activity."; /evidence="ECO:0000269|PubMed:16219293, ECO:0000269|PubMed:18991813
uniprot
proteins
protein_family
Janus family
uniprot
proteins
pubmed
10931946
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11342225
uniprot
proteins
pubmed
12383260
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16219293
uniprot
proteins
pubmed
16990267
uniprot
proteins
pubmed
18991813
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19836471
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
25574816
uniprot
proteins
sequence_length
125
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins