CYP2D7
entrez
1564
canonical
uniprot
A0A087X1C5
canonical
genesymbol
CYP2D7
resolver
hgnc
HGNC:2624
resolver
uniprot
Q6XP50
resolver
uniprot_entry
CP2D7_HUMAN
resolver
uniprot_sec
Q6XP50
resolver
amino_acid_sequence
MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEKAKGSPESSFNDENLRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCPIVGTHVCPVRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR
uniprot
proteins
ec_number
1.14.14.1
uniprot
proteins
function
FUNCTION: May be responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It may be involved in the metabolism of codeine to morphine (PubMed:15051713). However, another study could not confirm it (PubMed:18838503). {ECO:0000269|PubMed:15051713, ECO:0000269|PubMed:18838503}.
uniprot
proteins
mass_dalton
57489
uniprot
proteins
protein_family
Cytochrome P450 family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
15051713
uniprot
proteins
pubmed
16169517
uniprot
proteins
pubmed
17494644
uniprot
proteins
pubmed
18838503
uniprot
proteins
sequence_length
515
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000305|PubMed:15051713}. Mitochondrion {ECO:0000269|PubMed:18838503}.
uniprot
proteins
transmembrane_region
TRANSMEM 3..23; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 302..322; /note="Helical; Name=2"; /evidence="ECO:0000255
uniprot
proteins