Tmem225
entrez
75667
canonical
uniprot
Q9D9S2
canonical
ensembl
ENSMUSG00000040541
resolver
ensp
ENSMUSP00000036816
resolver
enst
ENSMUST00000046333
resolver
genesymbol
Tmem225
resolver
genesymbol_syn
Pmp22cd
resolver
uniprot_entry
TM225_MOUSE
resolver
amino_acid_sequence
MMHIPNRSIQAANIFFSSGAILLLIVGLIMEDWVELIPKVRKDKTTHSPWLGCCPPFWPEESLEVVRRIMRMTLNISIYLNLIIGLQFSYMISQNKCVHLLVGFLSFFAGCLLFYAIIVYHHKLNKGQYVYFVNYKTKWIAFTVYLTIALFLTCGIFCFIQSTNRCECMKFCIPHTESKSQEMIPSTIEVVSLPPRCAMPRSIVHVHSVTSKDGSLNRPHTQARRVTWAL
uniprot
proteins
function
FUNCTION: Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC. {ECO:0000269|PubMed:25605614}.
uniprot
proteins
mass_dalton
26483
uniprot
proteins
mutagenesis
MUTAGEN 224..228; /note="Missing: Abolishes interaction with PPP1CC."; /evidence="ECO:0000269|PubMed:25605614
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
25605614
uniprot
proteins
sequence_length
230
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000269|PubMed:25605614}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 72..92; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 140..160; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins