E2f2
entrez
242705
canonical
uniprot
P56931
canonical
ensembl
ENSMUSG00000018983
resolver
ensp
ENSMUSP00000050047
resolver
enst
ENSMUST00000061721
resolver
genesymbol
E2f2
resolver
uniprot
A2AW43
resolver
uniprot
Q8BID0
resolver
uniprot
Q8BJ38
resolver
uniprot_entry
E2F2_MOUSE
resolver
uniprot_entry
Q8BJ38_MOUSE
resolver
uniprot_sec
A2AW43
resolver
uniprot_sec
Q8BID0
resolver
amino_acid_sequence
MLRAPRTLAPATAQPTKSLPALNPTELWPSGLSSPQLCPATTATTYYTSLYTQTVPSSVALGTCLDATPHGPEGQIVRCAPAGRLPAKRKLDLEGIGRPTVPEFRTPKGKCIRVDGLPSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKSKNNIQWVGRELFEDPTRPSRQQQLGQELKELMNAEQTLDQLIQSCSLSFKHLTEDNANKKLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRAEENLQIYLKSTQGPIEVYLCPEEGQEPDSPAKEALPSTSALSPIPDCAQPGCSTDSGIAETIEPSVLIPQPIPPPPPPPLPPAPSLVPLEATDNMLELSHPLLQQTEDQFLSPILAANSPLISFSPPLDQDEYLWGMDEGEGISDLFDSYDLGDLLIN
uniprot
proteins
function
FUNCTION: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.
uniprot
proteins
mass_dalton
48499
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase. {ECO:0000250}.
uniprot
proteins
protein_family
E2F/DP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15716352
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
9149906
uniprot
proteins
pubmed
9376316
uniprot
proteins
sequence_length
443
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins