Syt5
entrez
53420
canonical
uniprot
Q9R0N5
canonical
ensembl
ENSMUSG00000004961
resolver
ensp
ENSMUSP00000070322
resolver
ensp
ENSMUSP00000171904
resolver
ensp
ENSMUSP00000171905
resolver
enst
ENSMUST00000065957
resolver
genesymbol
Syt5
resolver
genesymbol_syn
Syt9
resolver
uniprot_entry
SYT5_MOUSE
resolver
amino_acid_sequence
MFPEPPTLGSPAPKTPPDSSRIRQGAVPAWVLATIVLGSGLLVFSSCFCLYRKRCRRRMGKKSQAQAQVHLQEVKELGRSYIDKVQPEIEELDRSPSMPGQQVSDKHQLGRLQYSLDYDFQTGQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAVGGAGLRHWADMLANPRRPIAQWHSLRPPDRARPIPAP
uniprot
proteins
function
FUNCTION: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface. {ECO:0000269|PubMed:11751925}.
uniprot
proteins
mass_dalton
43130
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
10531343
uniprot
proteins
pubmed
11751925
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:11751925}; Single-pass membrane protein {ECO:0000269|PubMed:11751925}. Recycling endosome membrane {ECO:0000269|PubMed:11751925}; Single-pass membrane protein {ECO:0000269|PubMed:11751925}. Note=In mast cells, localizes to the endocytic recycling compartment.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins