MIDN
entrez
90007
canonical
uniprot
Q504T8
canonical
ensembl
ENSG00000167470
resolver
ensp
ENSP00000300952
resolver
ensp
ENSP00000467679
resolver
ensp
ENSP00000507955
resolver
ensp
ENSP00000542639
resolver
ensp
ENSP00000607389
resolver
ensp
ENSP00000607390
resolver
ensp
ENSP00000607391
resolver
ensp
ENSP00000607392
resolver
ensp
ENSP00000607393
resolver
enst
ENST00000300952
resolver
enst
ENST00000591446
resolver
enst
ENST00000682408
resolver
enst
ENST00000937331
resolver
enst
ENST00000937332
resolver
enst
ENST00000937333
resolver
enst
ENST00000937334
resolver
genesymbol
MIDN
resolver
hgnc
HGNC:16298
resolver
uniprot
A0A804HKJ8
resolver
uniprot
Q96BW8
resolver
uniprot_entry
A0A804HKJ8_HUMAN
resolver
uniprot_entry
MIDN_HUMAN
resolver
uniprot_sec
Q96BW8
resolver
amino_acid_sequence
MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAARGDPSIASPVSSPCRPVSSAARVPPVPTSPSPASPSPITAGSFRSHAASTTCPEQMDCSPTASSSASPGASTTSTPGASPAPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLAQLRCHAQCSPASPAPDLAPRTTSCEKLTAAPSASLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWSPSRKAGRSDSSSSGGGGSPSEASGLGLDFEDSVWKPEVNPDIKSEFVVA
uniprot
proteins
function
FUNCTION: Facilitates the ubiquitin-independent proteasomal degradation of stimulus-induced transcription factors such as FOSB, EGR1, NR4A1, and IRF4 to the proteasome for degradation (PubMed:37616343). Promotes also the degradation of other substrates such as CBX4 (By similarity). Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion. {ECO:0000250|UniProtKB:D4AE48, ECO:0000250|UniProtKB:Q3TPJ7, ECO:0000269|PubMed:37616343}.
uniprot
proteins
mass_dalton
49213
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24187134
uniprot
proteins
pubmed
37616343
uniprot
proteins
sequence_length
468
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q3TPJ7}. Nucleus {ECO:0000269|PubMed:24187134, ECO:0000269|PubMed:37616343}. Cytoplasm, cytosol {ECO:0000269|PubMed:24187134}. Note=Detected in the nucleus and nucleolus with no expression in the cytoplasm (By similarity). However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus (PubMed:24187134). {ECO:0000250|UniProtKB:Q3TPJ7, ECO:0000269|PubMed:24187134}.
uniprot
proteins