Mgat4a
entrez
269181
canonical
uniprot
Q812G0
canonical
ensembl
ENSMUSG00000026110
resolver
ensp
ENSMUSP00000114175
resolver
ensp
ENSMUSP00000121181
resolver
ensp
ENSMUSP00000313087
resolver
ensp
ENSMUSP00000346716
resolver
genesymbol
Mgat4a
resolver
uniprot
Q3TQT1
resolver
uniprot
Q80UI0
resolver
uniprot_entry
MGT4A_MOUSE
resolver
uniprot_sec
Q3TQT1
resolver
uniprot_sec
Q80UI0
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by UDP. {ECO:0000250|UniProtKB:O77836}.
uniprot
proteins
amino_acid_sequence
MRLRNGTVATALVFVTSFLTLSWYTTWQNGKEKLIAYQREFLALKERLRVAEHRISQRSSELNTIVQQFRRAGAETNGSKTALSTISDNTIKLLKELTSKKSLRVPSIYYHLPHLLQNERSLQPAVQIGSGRTGVSIVMGIPTVKREVKSYLVETLHSLIDNLYPEEKLDCVIVVFIGETDLDYVHSVVANLEKEFSREISSGLLEIISPPESYYPDLTNLKETFGDSKERVRWRTKQNLDYCFLMMYAQEKGIYYIQLEDDIIVKQNYFNTIKNFALQLSSEEWMILEFSQLGFIGKMFQAPDLALVVEFILMFYKEKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFRPSLFQHVGLHSSLSGKIQKLTDKDYMKPLLLKVHVNPPAEVSTSLKVYQGHTLEKTYMGEDFFWAITPTAGDYILFKFDKPVNVESYLFHSGNQEHPGDILLNTTVDVLPLKSDSLEISKETKDKRLEDGYFRIGKFEYGVAEGIVDPGLNPISAFRLSVIQNSAVWAILNEIHIKKVTS
uniprot
proteins
ec_number
2.4.1.145
uniprot
proteins
function
FUNCTION: Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:16377570). Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (PubMed:16377570). {ECO:0000269|PubMed:16377570}.
uniprot
proteins
mass_dalton
61480
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000269|PubMed:16377570}.
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:O77836}.
uniprot
proteins
protein_family
Glycosyltransferase 54 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16377570
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9D4R2}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9D4R2}.; SUBCELLULAR LOCATION: [Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form]: Secreted {ECO:0000250|UniProtKB:O77836}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..27; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins