St8sia4
entrez
20452
canonical
uniprot
Q64692
canonical
ensembl
ENSMUSG00000040710
resolver
ensp
ENSMUSP00000043477
resolver
ensp
ENSMUSP00000140534
resolver
ensp
ENSMUSP00000239960
resolver
ensp
ENSMUSP00000239961
resolver
enst
ENSMUST00000043336
resolver
enst
ENSMUST00000189556
resolver
genesymbol
St8sia4
resolver
genesymbol_syn
Pst
resolver
genesymbol_syn
ST8SiaIV
resolver
genesymbol_syn
Siat8d
resolver
uniprot
A0A087WRA0
resolver
uniprot
Q53WR7
resolver
uniprot
Q6PAS1
resolver
uniprot_entry
A0A087WRA0_MOUSE
resolver
uniprot_entry
Q53WR7_MOUSE
resolver
uniprot_entry
Q6PAS1_MOUSE
resolver
uniprot_entry
SIA8D_MOUSE
resolver
amino_acid_sequence
MRSIRKRWTICTISLLLIFYKTKEIARTEEHQETQLIGDGELCLSRSLVNSSDKIIRKAGSTIFQHSVQGWKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHNLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSGCGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLQVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCMKQ
uniprot
proteins
ec_number
2.4.3.-
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of a sialic acid from a CMP-linked sialic acid donor onto a terminal alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid of an N-linked glycan protein acceptor through alpha-2,8-linkages (PubMed:8690732). Therefore, participates in polysialic acid synthesis on various sialylated N-acetyllactosaminyl oligosaccharides, including NCAM1 N-glycans, FETUB N-glycans and AHSG (By similarity). It is noteworthy that alpha-2,3-linked sialic acid is apparently a better acceptor than alpha-2,6-linked sialic acid (By similarity). {ECO:0000250|UniProtKB:Q92187, ECO:0000269|PubMed:8690732}.
uniprot
proteins
mass_dalton
41256
uniprot
proteins
post_translational_modification
PTM: Autopolysialylated. {ECO:0000250|UniProtKB:Q92187}.
uniprot
proteins
protein_family
Glycosyltransferase 29 family
uniprot
proteins
pubmed
8690732
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q92187}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q92187}. Secreted {ECO:0000250|UniProtKB:Q92187}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..20; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins