Cdk10
entrez
361434
canonical
uniprot
Q4KM47
canonical
ensembl
ENSRNOG00000016088
resolver
ensp
ENSRNOP00000021607
resolver
ensp
ENSRNOP00000059465
resolver
enst
ENSRNOT00000021607
resolver
enst
ENSRNOT00000066552
resolver
genesymbol
Cdk10
resolver
uniprot
F1LSV8
resolver
uniprot
G3V814
resolver
uniprot_entry
CDK10_RAT
resolver
uniprot_entry
F1LSV8_RAT
resolver
uniprot_entry
G3V814_RAT
resolver
amino_acid_sequence
MSQCQIWVRHHLCCSFQIPTLAASLFQLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCILLQVLRGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPAATEGQSKRCRP
uniprot
proteins
ec_number
2.7.11.22
uniprot
proteins
function
FUNCTION: Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling. {ECO:0000250|UniProtKB:Q15131}.
uniprot
proteins
mass_dalton
40634
uniprot
proteins
protein_family
CDC2/CDKX subfamily
uniprot
proteins
protein_family
CMGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
358
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q15131}.
uniprot
proteins