Homer3
entrez
29548
canonical
uniprot
Q9Z2X5
canonical
ensembl
ENSRNOG00000020229
resolver
ensp
ENSRNOP00000027428
resolver
ensp
ENSRNOP00000091926
resolver
ensp
ENSRNOP00000093275
resolver
ensp
ENSRNOP00000107309
resolver
enst
ENSRNOT00000027428
resolver
enst
ENSRNOT00000098457
resolver
enst
ENSRNOT00000108210
resolver
enst
ENSRNOT00000126363
resolver
genesymbol
Homer3
resolver
genesymbol_syn
Vesl3
resolver
uniprot
A0A8I6AH27
resolver
uniprot
A0A8I6AJC0
resolver
uniprot
A0A8L2QEN4
resolver
uniprot
A0ABK0LTA8
resolver
uniprot
Q6IRH2
resolver
uniprot_entry
A0A8I6AH27_RAT
resolver
uniprot_entry
A0A8I6AJC0_RAT
resolver
uniprot_entry
A0A8L2QEN4_RAT
resolver
uniprot_entry
A0ABK0LTA8_RAT
resolver
uniprot_entry
HOME3_RAT
resolver
uniprot_entry
Q6IRH2_RAT
resolver
amino_acid_sequence
MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFGSEQQLTQFAEKFQEVKEAARLAREKSQDGGELTSTALAMASHQVPPSPLVSTNGPEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNQRLAGALREANAAATQWRQQLEVQRAEAEHLRQRVAELEAQVAAEPVRAGEKEATSQSVEQLEARVQTKDQEIQTLKNQSTGPREAPDTAEREETQQQVQDLETRNAELEQQLRAMESNLEEARAERERARAEVGRAAQLLDVRLFELSELREGLARLAEAAP
uniprot
proteins
function
FUNCTION: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release (By similarity). Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q99JP6, ECO:0000250|UniProtKB:Q9NSC5}.
uniprot
proteins
mass_dalton
39891
uniprot
proteins
protein_family
Homer family
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
358
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Postsynaptic density {ECO:0000250}. Synapse {ECO:0000250}. Note=Postsynaptic density of neuronal cells. {ECO:0000250}.
uniprot
proteins