TNP2
entrez
7142
canonical
uniprot
Q05952
canonical
ensembl
ENSG00000178279
resolver
ensp
ENSP00000325738
resolver
enst
ENST00000312693
resolver
genesymbol
TNP2
resolver
hgnc
HGNC:11952
resolver
uniprot
Q4VB56
resolver
uniprot
Q9NZB0
resolver
uniprot_entry
Q4VB56_HUMAN
resolver
uniprot_entry
STP2_HUMAN
resolver
uniprot_sec
Q9NZB0
resolver
amino_acid_sequence
MDTQTHSLPITHTQLHSNSQPQSRTCTRHCQTFSQSCRQSHRGSRSQSSSQSPASHRNPTGAHSSSGHQSQSPNTSPPPKRHKKTMNSHHSPMRPTILHCRCPKNRKNLEGKLKKKKMAKRIQQVYKTKTRSSGWKSN
uniprot
proteins
function
FUNCTION: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. {ECO:0000250|UniProtKB:P11378}.
uniprot
proteins
mass_dalton
15641
uniprot
proteins
protein_family
Nuclear transition protein 2 family
uniprot
proteins
pubmed
10659848
uniprot
proteins
pubmed
1385303
uniprot
proteins
pubmed
7983046
uniprot
proteins
pubmed
8428967
uniprot
proteins
pubmed
9809674
uniprot
proteins
sequence_length
138
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P11101}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P11101}. Chromosome {ECO:0000250|UniProtKB:P11101}. Note=Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is mediated by IPO4. Nucleolar localization requires the protein to be phosphorylated (By similarity). {ECO:0000250|UniProtKB:P11101, ECO:0000250|UniProtKB:P11378}.
uniprot
proteins