Sgsm3
entrez
105835
canonical
uniprot
Q8VCZ6
canonical
ensembl
ENSMUSG00000042303
resolver
ensp
ENSMUSP00000122543
resolver
ensp
ENSMUSP00000155794
resolver
ensp
ENSMUSP00000229740
resolver
ensp
ENSMUSP00000229742
resolver
enst
ENSMUST00000139517
resolver
genesymbol
Sgsm3
resolver
genesymbol_syn
Cip85
resolver
genesymbol_syn
Rutbc3
resolver
uniprot
Q3TCB6
resolver
uniprot_entry
SGSM3_MOUSE
resolver
uniprot_sec
Q3TCB6
resolver
amino_acid_sequence
MSGNHTPSASGPFSALTPSIWPQEILAKYSQKEESSEQPELCYDEFGFRVDKEGSEPGCSQMTGSPLVEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKKNSELSYREIIKNSSNDETIAAKQIEKDLLRTMPSNACFANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLFFYEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMRLAGSLTDVAVETQRRKHLAYLIADQGQTLGTGTTTNLSQVVRRRTQRRKSGITSLLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACLRSHRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNVTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPARREEEKQPLKEGVQDMLVKHHLFSWDIDG
uniprot
proteins
function
FUNCTION: GTPase-activating protein (GAP) specific for Rab5 small GTPase for which it accelerates the intrinsic GTP hydrolysis rate, thereby controlling trafficking through the early endocytic pathway. May play a cooperative role in NF2-mediated growth suppression of cells. {ECO:0000250|UniProtKB:Q96HU1}.
uniprot
proteins
mass_dalton
85490
uniprot
proteins
protein_family
Small G protein signaling modulator family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15709751
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17509819
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
750
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96HU1}.
uniprot
proteins