TM4SF4
entrez
7104
canonical
uniprot
P48230
canonical
ensembl
ENSG00000169903
resolver
ensp
ENSP00000305852
resolver
enst
ENST00000305354
resolver
genesymbol
TM4SF4
resolver
genesymbol_syn
ILTMP
resolver
hgnc
HGNC:11856
resolver
uniprot
B2RDA4
resolver
uniprot_entry
T4S4_HUMAN
resolver
uniprot_sec
B2RDA4
resolver
amino_acid_sequence
MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMIFPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLMANSTWGYPFHDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVNGLLGTLCGDCQCCGCCGGDGPV
uniprot
proteins
function
FUNCTION: Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
uniprot
proteins
mass_dalton
21396
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. Glycosylation is required for the growth inhibitory effect. {ECO:0000269|PubMed:19159218}.
uniprot
proteins
protein_family
L6 tetraspanin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
7665614
uniprot
proteins
sequence_length
202
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 10..30; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 46..66; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 94..114; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 159..179; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins