Acsm1
entrez
117147
canonical
uniprot
Q91VA0
canonical
ensembl
ENSMUSG00000033533
resolver
ensp
ENSMUSP00000036140
resolver
ensp
ENSMUSP00000215868
resolver
genesymbol
Acsm1
resolver
genesymbol_syn
Bucs1
resolver
genesymbol_syn
Lae
resolver
genesymbol_syn
Macs1
resolver
uniprot
Q3UED4
resolver
uniprot_entry
ACSM1_MOUSE
resolver
uniprot_sec
Q3UED4
resolver
amino_acid_sequence
MQWLKSFQICKVLQGFSLSPTQLHRRLFSRVGAPRWNDHDSPEEFNFASDVLDYWAQMEEEGKRGPSPAFWWVNGQGDEIKWSFRKLRDLTCRTANVFEQICGLQQGDHLALILPRVPEWWLVTVGCMRTGIIFMPGTTQLKAKDILYRIQISRAKAIVTTASLVPEVESVASECPDLKTKLVVSDHSHEGWLDFCSLIKSASPDHTCIKSKMKDPMAIFFTSGTTGYPKMAKHNQGLAFRSYIPSCRKLLKLKTSDILWCMSDPGWILATVGCLIEPWTSGCTVFIHHLPQFDPKVIVEVLFKYPITQCLAAPGVYRMVLQQKTSNLRFPTLEHCTTGGESLLPEEYEQWKQRTGLSIHEVYGQSETGISSATLREMKIKRGSIGKAILPFDLQIIDEKGNILPPNTEGYIGIRIKPTRPLGLFMEYENSPESTSEVECGDFYNSGDRATIDEEGYIWFLGRGDDVINASGYRIGPVEVENALAEHPAVAESAVVSSPDKDRGEVVKAFIVLNPEFLSHDQEQLIKELQHHVKSVTAPYKYPRKVEFVSELPKTVTGKIKRKELRNKEFGQL
uniprot
proteins
ec_number
6.2.1.2
uniprot
proteins
ec_number
6.2.1.25
uniprot
proteins
function
FUNCTION: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed:11470804, PubMed:12709059). Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate (PubMed:11470804, PubMed:12709059). Also catalyzes the activation of lipoate to lipoyl-nucleoside monophosphate (By similarity). Activates lipoate with GTP at a 1000-fold higher rate than with ATP and activates both (R)- and (S)-lipoate to the respective lipoyl-GMP, with a preference for (R)-lipoate (By similarity). {ECO:0000250|UniProtKB:Q9BEA2, ECO:0000269|PubMed:11470804, ECO:0000269|PubMed:12709059}.
uniprot
proteins
mass_dalton
64760
uniprot
proteins
protein_family
ATP-dependent AMP-binding enzyme family
uniprot
proteins
pubmed
11470804
uniprot
proteins
pubmed
12709059
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16378734
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
573
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:11470804}. Mitochondrion {ECO:0000269|PubMed:12709059}.
uniprot
proteins