Gpr135
entrez
314213
canonical
uniprot
Q7TQN7
canonical
ensembl
ENSRNOG00000004499
resolver
ensembl
ENSRNOG00055010048
resolver
ensp
ENSRNOP00000005933
resolver
ensp
ENSRNOP00000100567
resolver
ensp
ENSRNOP00055013640
resolver
enst
ENSRNOT00000005933
resolver
enst
ENSRNOT00000131704
resolver
enst
ENSRNOT00055016949
resolver
genesymbol
Gpr135
resolver
uniprot_entry
GP135_RAT
resolver
amino_acid_sequence
MEEQARPPSRPAASATLPGSAHPGGAASTATAAALSFSSVATVTLGNQSDAGRPEAAGSRGPAPLLWHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFAPPGDSGPWRSFCAASRFFSSCFGIVSTFSVALISLDRYCAIVRPPRDKLGRRRALQLLAGAWLAALGFSLPWELLRAPREPPTPQSFHRCLYRTSPDPAQLGAAYSVGLVVACYLLPFLLMCFCRYHICKTVRLSDVRVRPMTTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAATRQGQTTQAPSLLNVAAVWLTWANGAINPVIYAIRNPNISMFLGRNREEGYRTRNMDVFLPSQGLGFQARSRNRLRNGCANRLGACSRMPSSNPASGSGGEVVMWARKNPVVLFFREDPPDPVMAVYKQHKSETRDSSI
uniprot
proteins
function
FUNCTION: Orphan receptor. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). {ECO:0000250|UniProtKB:Q8IZ08}.
uniprot
proteins
mass_dalton
49581
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
14623098
uniprot
proteins
sequence_length
457
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8IZ08}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000250|UniProtKB:Q8IZ08}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome. {ECO:0000250|UniProtKB:Q8IZ08}.
uniprot
proteins
transmembrane_region
TRANSMEM 65..85; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 110..130; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 157..177; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 190..210; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 236..256; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 296..316; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 330..350; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins