Cacna2d1
entrez
12293
canonical
uniprot
O08532
canonical
ensembl
ENSMUSG00000040118
resolver
ensp
ENSMUSP00000049457
resolver
ensp
ENSMUSP00000077391
resolver
ensp
ENSMUSP00000099117
resolver
ensp
ENSMUSP00000136260
resolver
ensp
ENSMUSP00000142881
resolver
ensp
ENSMUSP00000254748
resolver
ensp
ENSMUSP00000254753
resolver
ensp
ENSMUSP00000254754
resolver
ensp
ENSMUSP00000254755
resolver
ensp
ENSMUSP00000347215
resolver
genesymbol
Cacna2d1
resolver
genesymbol_syn
Cacna2
resolver
uniprot
A0A411ACY8
resolver
uniprot
O08533
resolver
uniprot
O08534
resolver
uniprot
O08535
resolver
uniprot
O08536
resolver
uniprot
Q14BH8
resolver
uniprot_entry
A0A411ACY8_MOUSE
resolver
uniprot_entry
CA2D1_MOUSE
resolver
uniprot_entry
Q14BH8_MOUSE
resolver
uniprot_sec
O08533
resolver
uniprot_sec
O08534
resolver
uniprot_sec
O08535
resolver
uniprot_sec
O08536
resolver
amino_acid_sequence
MAAGCLLALTLTLFQSGLIGPSSEEPFPSPVTIKSWVDKMQEDLVTLAKTASGVTQLADIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLAMEAEKVQAAHQWREDFASNEVVYYNAKDDLDPERNESEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKRNRDEDPTLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNVTGQSENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGVGIPTINLRKRRPNVQNPKSQEPVTLDFLDAELENEIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARYSETLKPDNFEESGYTFIAPREYCNDLKPSDNNTEFLLNFNEFIDRKTPNNPSCNTDLINRILLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVELYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSMMRHLVNISLYAFNKSYDYQSVCDPGAAPKQGAGHRSAYVPSIADILQIGWWATAAAWSILQQLLLSLTFPRLLEAVEMEEDDFTASLSKQSCITEQTQYFFKNDTKSFSGLLDCGNCSRIFHVEKLMNTNLVFIMVESKGTCPCDTRLLMQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWSIFGLQFILLWLVSGSRHYLL
uniprot
proteins
function
FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (By similarity). Plays an important role in excitation-contraction coupling (By similarity). {ECO:0000250|UniProtKB:P54289}.
uniprot
proteins
mass_dalton
124630
uniprot
proteins
post_translational_modification
PTM: Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked. {ECO:0000250}.
uniprot
proteins
protein_family
Calcium channel subunit alpha-2/delta family
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
19656770
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8955374
uniprot
proteins
sequence_length
1103
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell membrane {ECO:0000250|UniProtKB:P54289}.
uniprot
proteins
transmembrane_region
TRANSMEM 1074..1094; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins