BLOC1S4
entrez
55330
canonical
uniprot
Q9NUP1
canonical
ensembl
ENSG00000186222
resolver
ensp
ENSP00000318128
resolver
enst
ENST00000320776
resolver
genesymbol
BLOC1S4
resolver
genesymbol_syn
CNO
resolver
hgnc
HGNC:24206
resolver
uniprot
Q6NVY6
resolver
uniprot
Q96G84
resolver
uniprot_entry
BL1S4_HUMAN
resolver
uniprot_sec
Q6NVY6
resolver
uniprot_sec
Q96G84
resolver
amino_acid_sequence
MEGSFSDGGALPEGLAEEAEPQGAAWSGDSGTVSQSHSSASGPWEDEGAEDGAPGRDLPLLRRAAAGYAACLLPGAGARPEVEALDASLEDLLTRVDEFVGMLDMLRGDSSHVVSEGVPRIHAKAAEMRRIYSRIDRLEAFVRMVGGRVARMEEQVTKAEAELGTFPRAFKKLLHTMNVPSLFSKSAPSRPQQAGYEAPVLFRTEDYFPCCSERPQL
uniprot
proteins
function
FUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:17182842}.
uniprot
proteins
mass_dalton
23351
uniprot
proteins
protein_family
BLOC1S4 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17182842
uniprot
proteins
pubmed
22203680
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
217
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins