B3glct
entrez
381694
canonical
uniprot
Q8BHT6
canonical
ensembl
ENSMUSG00000051950
resolver
ensp
ENSMUSP00000097972
resolver
genesymbol
B3glct
resolver
genesymbol_syn
B3galtl
resolver
genesymbol_syn
Gm1057
resolver
uniprot
E9QMK8
resolver
uniprot
Q0PCR7
resolver
uniprot
Q149S5
resolver
uniprot_entry
B3GLT_MOUSE
resolver
uniprot_sec
E9QMK8
resolver
uniprot_sec
Q0PCR7
resolver
uniprot_sec
Q149S5
resolver
amino_acid_sequence
MRPPALLALFSCSAAFALMSEEIKEKVTPSQDLRQSSLPGRHDIDLKEIVFVIQSQSNSFHAKRAEQLKKNILKQAANLTQDLPRVLLLHQLAKQEGAWTILPLLPHFSVTYSKNSAWIFFCEEETRLQIPRLLDTLRRYDPSKEWFLGKALYDEESTIIHHYAFSENPTVFKYPDFAAGWALSIPLVNKLAKRLKSEALKSDFTIDLKHEIALYIWDKGGGPALTPVPEFCTEDVDPRCVTTFHSFLPLCGVPVKKEEIFVAVKTCKKFHADRIPIVKKTWAAQASLIEYYSDYAETAIPTVDLGIPNTDRGHCGKTFAILEKFLNHSHNKISWLVIVDDDTLISISRLRHLLSCYDSSDPVFLGERYGYGLGTGGYSYVTGGGGMVFSREAIRRLLVSSCRCYSNDAPDDMVLGMCFSGLGVPVTHSPLFHQARPVDYPKDYLAHQIPVSFHKHWHIDPVKVYLTWLAPSEEDQATQETQKDPREEL
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
function
FUNCTION: Beta-1,3-glucosyltransferase involved in one of the two pathways responsible for protein O-linked fucosylation, a unique post-translational modification of cysteine-knotted proteins that regulates various biological processes. This pathway targets proteins with Thrombospondin type-1 (TSP1) repeats (TSR) in the endoplasmic reticulum. It starts with POFUT2, which attaches fucose via an O-glycosidic bond to a conserved serine or threonine residue. B3GLCT extends this modification by transferring a glucose molecule from UDP-glucose to the fucose. {ECO:0000250|UniProtKB:Q6Y288}.
uniprot
proteins
mass_dalton
55358
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q6Y288}.
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16899492
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
489
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q6Y288, ECO:0000255|PROSITE-ProRule:PRU10138}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q6Y288}.
uniprot
proteins
transmembrane_region
TRANSMEM 2..22; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins