Timm21
entrez
67105
canonical
uniprot
Q8CCM6
canonical
ensembl
ENSMUSG00000024645
resolver
ensp
ENSMUSP00000025547
resolver
genesymbol
Timm21
resolver
genesymbol_syn
Tim21
resolver
uniprot
Q3THX0
resolver
uniprot
Q8CE44
resolver
uniprot
Q9CYU8
resolver
uniprot
Q9CZS4
resolver
uniprot_entry
TIM21_MOUSE
resolver
uniprot_sec
Q3THX0
resolver
uniprot_sec
Q8CE44
resolver
uniprot_sec
Q9CYU8
resolver
uniprot_sec
Q9CZS4
resolver
amino_acid_sequence
MICAFLRVVQHAEKLHGSLGRQLLPHFVFTKACFKTQPLRWGLREQKITVQPRTVLRFTQKTFWTQGPDPRKAKEDSTKQVSIRRNQREETGVSMSQKVREAGRDVSYLIVVLFGVGLTGGLLYAIFKELFFSSSPNIIYGKALGKCRTHPEVIGVFGEPLKGYGEMSRRGRRQHVRFSEYVNNGLKRIRVKFYIEGSEPGKQGTVHAEVEENPGSGQFEFRYIFVEVTPTRSIIVEDNRSEQS
uniprot
proteins
function
FUNCTION: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. {ECO:0000250|UniProtKB:Q9BVV7}.
uniprot
proteins
mass_dalton
27911
uniprot
proteins
protein_family
TIM21 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
244
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 107..127; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins