Suppressor of RNA silencing
uniprot_keyword
KW-0941
canonical
name
Suppressor of RNA silencing
uniprot
synonym
Suppressor of RNA interference
uniprot
synonym
Suppressor of RNAi
uniprot
definition
Protein which suppresses host RNA-mediated gene silencing. The most common form of RNA-mediated gene silencing is RNA interference (RNAi), a sequence-specific RNA-degradation mechanism that operates as a natural antiviral system in plants and invertebrates cells. RNAi is mediated by small interfering RNAs (siRNA) of about 21- to 25-nt that target homologous RNAs for destruction. RNA silencing by endogenous micro-RNAs (miRNAs) may also play a role in the antiviral defences of mammals. miRNAs differ from siRNAs in that they generally base pair imperfectly with target RNAs and inhibit their translation by an unknown mechanism.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords