Igsf1
entrez
209268
canonical
uniprot
Q7TQA1
canonical
ensembl
ENSMUSG00000031111
resolver
ensp
ENSMUSP00000033442
resolver
ensp
ENSMUSP00000071919
resolver
ensp
ENSMUSP00000110541
resolver
ensp
ENSMUSP00000110543
resolver
ensp
ENSMUSP00000231049
resolver
ensp
ENSMUSP00000231050
resolver
ensp
ENSMUSP00000231051
resolver
ensp
ENSMUSP00000231053
resolver
ensp
ENSMUSP00000231055
resolver
genesymbol
Igsf1
resolver
genesymbol_syn
Kiaa0364
resolver
uniprot
Q6ZQD0
resolver
uniprot
Q7TQ99
resolver
uniprot
Q7TQA0
resolver
uniprot
Q8BMN5
resolver
uniprot_entry
IGSF1_MOUSE
resolver
uniprot_sec
Q6ZQD0
resolver
uniprot_sec
Q7TQ99
resolver
uniprot_sec
Q7TQA0
resolver
uniprot_sec
Q8BMN5
resolver
amino_acid_sequence
MMLRTFTLLLLCIWLNPGMTSLAVESQPELWIESNYPQAPWENITLWCKSPSRVSSKFLLLKDNSQMTWIRPPYKTFQVSFFIGALTESNTGLYRCCYWKEKGWSKPSKILELEAPGQLPKPIFWIQAETPPLPGCNVNIFCHGWLQDLVFMLFKEGYTEPVDYQVPTGTMAIFSIDNLAPENEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPILAPGESLSLRCQGPIYGMTFALMRLEDLKKSFYHKKPIKNEAYFYFQDLKIQDTGHYLCFYYDGSYRGSLLSDILKIWVTDTFPKTWLLVQPSPVIQMGQNVSLRCGGLMDGVGLALYKKGEEKPLQFLDASSNTGNNSFFLKNVTYRDAGIYSCHYYLTWKTSIKMATYNTVELMVVAWPSSVFKVGKTITLQCRVSHPVLEFSLEWEERTTFQKFSVDGDFLITDIEGQGTGTYSCSYRIEAHPNTWSHRSKPLKLVGPAGFLTWNSILNEAVRVSLTMQLASLLLLVVWIRWKCRRLRLREAWLLGTAQGVAMLFILMALLCCGLCNGALTEEIEIVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTHSHTGSYHCHSWEEMAVSEPSEALELVGTDILPKPVISASLPIRGQELQIRCKGWLEGLGFALYKKGEQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEMQPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGSRVTFNCSTSHEHMSFILYKDGNEIASSDLAWGNPGGSTAHFLIISVGIGDGGNYSCRYYDFSIWSEPSNPVELVVTEFYPKPTLLAQPGPVVLPGKNVTLRCQGIFQGMRFALLQEGTHTPLQFQSTSGTSADFLLHTVGAQDFGNYSCVYYETTMSNRGSSLSTPLMIWVTDTFPRPWLSAEPSSVVTMGQNVTLWCQGPVRGVGYILHKEGEATSMQLWGSTSNEGAFPIINISGASIGRYSCCYHPDWMSPIKIQPSNTLELIVTGLLPKPSLLVQPGPMVAPGENVTLQCQGELPDSTFVLLKEGTRQPLEQQRPSGYRADFWMPVVRDQDSGVYSCVYYLDSAPLVASNHSNSLEIWVTDKPPKPSLSAWPSTIFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQQFSEDGDFVIDNLEGKGIGNYSCSYRLQAYPDIWSEPSDTLELVGAAGPVAQECTVGNIVRSTLIVVVVVALGIVLAVEWKKWPRLRTRGSETDGRDQTVVLEECNQEGEPGTTTNSPSSASQEVSVELTVPI
uniprot
proteins
function
FUNCTION: Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
147010
uniprot
proteins
pubmed
12832474
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23143598
uniprot
proteins
sequence_length
1317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 3]: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 4]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 5]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 500..520; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 532..552; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins