P23571
uniprot
P23571
canonical
activity_regulation
ACTIVITY REGULATION: Binding to SSBP1 in mitochondria inhibits glycosylase activity in the context of a single-stranded DNA (ssDNA), but not a double-stranded DNA (dsDNA) substrates. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
SKEPVSVVLPDAEHPAFPGRTRRPGNARAGSQVTGSREVGQMPAPLSRKIGQKKQQLAQSEQQQTPKEKLSSTPGLLRSIYFSSPEDRPARLGPEYFDQPAVTLARAFLGQVLVRRLADGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYLIYGMYFCLNVSSQGAGACVLLRALEPLEGLETMRQLRNSLRKSTVGRSLKDRELCNGPSKLCQALARSKSFDQRDLAQDEAVWLEHGPLESSSPAVVAAAAGIGHAGEWTQKPLRFYVQGSPWVSVVDRVAEQMYQPQQTACSDXALIVQK
uniprot
proteins
ec_number
3.2.2.21
uniprot
proteins
function
FUNCTION: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
uniprot
proteins
mass_dalton
34814
uniprot
proteins
protein_family
DNA glycosylase MPG family
uniprot
proteins
pubmed
1698614
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins