Cfap298
entrez
288269
canonical
uniprot
Q5U3Z0
canonical
ensembl
ENSRNOG00000021399
resolver
ensembl
ENSRNOG00055017025
resolver
ensembl
ENSRNOG00060017837
resolver
ensembl
ENSRNOG00065006665
resolver
ensp
ENSRNOP00000030489
resolver
ensp
ENSRNOP00055023279
resolver
ensp
ENSRNOP00060024743
resolver
ensp
ENSRNOP00065007546
resolver
enst
ENSRNOT00000030279
resolver
enst
ENSRNOT00055028924
resolver
enst
ENSRNOT00060030592
resolver
enst
ENSRNOT00065010316
resolver
genesymbol
Cfap298
resolver
uniprot_entry
CF298_RAT
resolver
amino_acid_sequence
MVVLHVKRGDESQFLLQAPGSTELEELTAQVTRVYNGRLKVHRLCTEIEELAEHGVFLPPNMQGLTDEQIEELKLKDEWGEKCVPSGGSVFTKDDIGRRNGHAPNEKMKQVLKKTVEEAKAMVSKKQVEAGVFVTMEMVKDALDQLRGAVMIVYPMGLPPYDPIRMEFENKEDLSGTQAALEVIQESEAQLWWAAKELRRTKKLSDYVGKNEKTKIIVKIQQRGQGAPAREPLISSEEHKQLMLFYHRRQEELKKLEENDDDSCLNSPWADNTALKRHFHGVKDIKWRPR
uniprot
proteins
function
FUNCTION: Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance of cilium motility. Required for correct positioning of cilia at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway. May suppress canonical Wnt signaling activity. {ECO:0000250|UniProtKB:Q6DRC3}.
uniprot
proteins
mass_dalton
33243
uniprot
proteins
protein_family
CFAP298 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24094744
uniprot
proteins
sequence_length
290
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:24094744}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A0A1L8HCK2}. Note=Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization. {ECO:0000269|PubMed:24094744}.
uniprot
proteins