Slc2a3
entrez
20527
canonical
uniprot
P32037
canonical
ensembl
ENSMUSG00000003153
resolver
ensp
ENSMUSP00000032476
resolver
enst
ENSMUST00000032476
resolver
genesymbol
Slc2a3
resolver
genesymbol_syn
Glut3
resolver
uniprot
Q3TPL8
resolver
uniprot
Q8BLF7
resolver
uniprot_entry
GTR3_MOUSE
resolver
uniprot_entry
Q3TPL8_MOUSE
resolver
uniprot_entry
Q8BLF7_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Deoxyglucose transport is inhibited by D-glucose, D-galactose and maltose. Galactose transport is inhibited by D-glucose and maltose. {ECO:0000250|UniProtKB:P11169}.
uniprot
proteins
amino_acid_sequence
MGTTKVTPSLVFAVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINKKEEDQATEILQRLWGTSDVVQEIQEMKDESVRMSQEKQVTVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDDYEAMSFVCIVAILIYVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGRTFEDIARAFEGQAHSGKGPAGVELNSMQPVKETPGNA
uniprot
proteins
function
FUNCTION: Facilitative glucose transporter (PubMed:35810171). Can also mediate the uptake of various other monosaccharides across the cell membrane (By similarity). Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate (By similarity). Does not mediate fructose transport (By similarity). Required for mesendoderm differentiation (PubMed:35810171). {ECO:0000250|UniProtKB:P11169, ECO:0000269|PubMed:35810171}.
uniprot
proteins
mass_dalton
53479
uniprot
proteins
protein_family
Glucose transporter subfamily
uniprot
proteins
protein_family
Major facilitator superfamily
uniprot
proteins
protein_family
Sugar transporter (TC 2.A.1.1) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1730609
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
35618043
uniprot
proteins
pubmed
35810171
uniprot
proteins
sequence_length
493
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:1730609, ECO:0000269|PubMed:35810171}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P11169}. Perikaryon {ECO:0000250|UniProtKB:Q07647}. Cell projection {ECO:0000250|UniProtKB:Q07647}. Note=Localized to densely spaced patches along neuronal processes. {ECO:0000250|UniProtKB:Q07647}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..32; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 65..85; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 91..111; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:P11169"; TRANSMEM 119..142; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 154..174; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 184..204; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 270..290; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 305..325; /note="Helical; Name=8"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 332..352; /note="Helical; Name=9"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 364..389; /note="Helical; Name=10"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 400..420; /note="Helical; Name=11"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 430..450; /note="Helical; Name=12"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255
uniprot
proteins