Nubp1
entrez
287042
canonical
uniprot
Q5I0L4
canonical
ensembl
ENSRNOG00000077863
resolver
ensembl
ENSRNOG00055018023
resolver
ensembl
ENSRNOG00060012974
resolver
ensembl
ENSRNOG00065002864
resolver
ensp
ENSRNOP00000105084
resolver
ensp
ENSRNOP00055024577
resolver
ensp
ENSRNOP00060017494
resolver
ensp
ENSRNOP00065002839
resolver
enst
ENSRNOT00000134135
resolver
enst
ENSRNOT00055030530
resolver
enst
ENSRNOT00060022079
resolver
enst
ENSRNOT00065003985
resolver
genesymbol
Nubp1
resolver
uniprot_entry
NUBP1_RAT
resolver
amino_acid_sequence
MEGAPHGCPGADSAQAGRGASCQGCPNQKLCASGAGAAPDPAVEEIREKMKTVRHRILVLSGKGGVGKSTFSAHLAHGLAEDGDTQVALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPVYVEDNLGVMSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGDVDYLVIDTPPGTSDEHLSVVQYLAAAHIDGAVILTTPQEVALQDVRKEISFCHKVKLPIIGVVENMSGFICPKCKRESQIFPPTTGGAEAMCQALKIPLLGKVPLDPHIGKSCDKGQSFFVEAPDSPATAAYKSIIQRIREFCNSRQSHDENLISP
uniprot
proteins
function
FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure. {ECO:0000250|UniProtKB:Q9R060, ECO:0000255|HAMAP-Rule:MF_03038}.
uniprot
proteins
mass_dalton
34045
uniprot
proteins
protein_family
Mrp/NBP35 ATP-binding proteins family
uniprot
proteins
protein_family
NUBP1/NBP35 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
320
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03038}. Nucleus {ECO:0000250|UniProtKB:Q9R060}. Cell projection {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q9R060}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9R060}. Note=Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis. Localized at centrioles and in the nucleus at interphase. Colocalizes with nubp-2 at prometaphase. Specifically localizes to the axenome of motile cilia as opposed to primary non-motile cilia. Localization is independent of NUBP2 and KIFC1. {ECO:0000250|UniProtKB:Q9R060}.
uniprot
proteins