Slc25a14
entrez
20523
canonical
uniprot
Q9Z2B2
canonical
ensembl
ENSMUSG00000031105
resolver
ensp
ENSMUSP00000033431
resolver
ensp
ENSMUSP00000110586
resolver
ensp
ENSMUSP00000120332
resolver
ensp
ENSMUSP00000181891
resolver
ensp
ENSMUSP00000181892
resolver
ensp
ENSMUSP00000181893
resolver
ensp
ENSMUSP00000181894
resolver
ensp
ENSMUSP00000181895
resolver
ensp
ENSMUSP00000181905
resolver
ensp
ENSMUSP00000181907
resolver
ensp
ENSMUSP00000181913
resolver
ensp
ENSMUSP00000181918
resolver
enst
ENSMUST00000134257
resolver
genesymbol
Slc25a14
resolver
genesymbol_syn
Bmcp1
resolver
genesymbol_syn
Ucp5
resolver
uniprot
A0A0A0MQJ8
resolver
uniprot
Q9ESI8
resolver
uniprot_entry
A0A0A0MQJ8_MOUSE
resolver
uniprot_entry
UCP5_MOUSE
resolver
uniprot_sec
Q9ESI8
resolver
amino_acid_sequence
MGIFPGIILIFLRVKFATAAVIVSGHQKSSTLSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQI
uniprot
proteins
function
FUNCTION: Transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate and glutamate and tricarboxylates. May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide. Also can mediate a very low unidirectional transport of anions including sulfate, phosphate, (S)-malate, citrate, L-aspartate and L-glutamate. Maintains oxidative balance (through uncoupling activities) and ATP production (by modifying mitochondrial membrane potential). Is able to transport protons across lipid membranes. Also exhibits transmembrane chloride transport activity to a lesser extent (By similarity). May modify mitochondrial respiratory efficiency and mitochondrial oxidant production (PubMed:11701769). {ECO:0000250|UniProtKB:O95258, ECO:0000269|PubMed:11701769}.
uniprot
proteins
mass_dalton
36286
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
10928996
uniprot
proteins
pubmed
11701769
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9852133
uniprot
proteins
sequence_length
325
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000305|PubMed:11701769}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 38..54; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 112..128; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 145..165; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 199..215; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 240..256; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 298..315; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins