FAXDC2
entrez
10826
canonical
uniprot
Q96IV6
canonical
ensembl
ENSG00000170271
resolver
ensp
ENSP00000320604
resolver
ensp
ENSP00000558461
resolver
ensp
ENSP00000558462
resolver
genesymbol
FAXDC2
resolver
genesymbol_syn
C5orf4
resolver
hgnc
HGNC:1334
resolver
uniprot
B4DIE1
resolver
uniprot
Q9BSX6
resolver
uniprot
Q9H8C7
resolver
uniprot_entry
FXDC2_HUMAN
resolver
uniprot_sec
B4DIE1
resolver
uniprot_sec
Q9BSX6
resolver
uniprot_sec
Q9H8C7
resolver
amino_acid_sequence
MKGEAGHMLHNEKSKQEGHIWGSMRRTAFILGSGLLSFVAFWNSVTWHLQRFWGASGYFWQAQWERLLTTFEGKEWILFFIGAIQVPCLFFWSFNGLLLVVDTTGKPNFISRYRIQVGKNEPVDPVKLRQSIRTVLFNQCMISFPMVVFLYPFLKWWRDPCRRELPTFHWFLLELAIFTLIEEVLFYYSHRLLHHPTFYKKIHKKHHEWTAPIGVISLYAHPIEHAVSNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCGYHLPFLPSPEFHDYHHLKFNQCYGVLGVLDHLHGTDTMFKQTKAYERHVLLLGFTPLSESIPDSPKRME
uniprot
proteins
function
FUNCTION: Promotes megakaryocyte differentiation by enhancing ERK phosphorylation and up-regulating RUNX1 expression. {ECO:0000269|PubMed:27689744}.
uniprot
proteins
mass_dalton
39002
uniprot
proteins
protein_family
Sterol desaturase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27689744
uniprot
proteins
sequence_length
333
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27689744}. Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 29..49; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 134..154; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 168..188; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 215..235; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 237..257; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins