Phox2a
entrez
116648
canonical
uniprot
Q62782
canonical
ensembl
ENSRNOG00000019706
resolver
ensp
ENSRNOP00000026702
resolver
enst
ENSRNOT00000026702
resolver
genesymbol
Phox2a
resolver
genesymbol_syn
Arix
resolver
genesymbol_syn
Pmx2a
resolver
uniprot
G3V8L2
resolver
uniprot_entry
G3V8L2_RAT
resolver
uniprot_entry
PHX2A_RAT
resolver
amino_acid_sequence
MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAATAKGAAGATGAKKGEARCSSEDDDSKESTCSHTPDSTASLPPPPPAPSLASPLLSPSPLPAALGSGPGPQPLKGALWAGVAGGGGGGPGTGAAELLKAWQPAEPGPGPFSGVLSSFHRKPGPALKTNLF
uniprot
proteins
function
FUNCTION: May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype (By similarity). {ECO:0000250|UniProtKB:Q62066}.
uniprot
proteins
mass_dalton
29525
uniprot
proteins
post_translational_modification
PTM: Monoubiquitinated at Lys-178 by the RNF220/ZC4H2 complex; leading to enhanced DNA-binding ability and transactivity. {ECO:0000250|UniProtKB:Q62066}.
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
8613746
uniprot
proteins
sequence_length
281
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
uniprot
proteins