RRAD
entrez
6236
canonical
uniprot
P55042
canonical
ensembl
ENSG00000166592
resolver
ensp
ENSP00000299759
resolver
ensp
ENSP00000559848
resolver
ensp
ENSP00000559849
resolver
ensp
ENSP00000559852
resolver
ensp
ENSP00000627096
resolver
ensp
ENSP00000627097
resolver
ensp
ENSP00000627098
resolver
ensp
ENSP00000627099
resolver
ensp
ENSP00000627100
resolver
ensp
ENSP00000627101
resolver
ensp
ENSP00000627104
resolver
enst
ENST00000299759
resolver
enst
ENST00000889788
resolver
enst
ENST00000889790
resolver
enst
ENST00000889793
resolver
enst
ENST00000957037
resolver
enst
ENST00000957038
resolver
enst
ENST00000957039
resolver
enst
ENST00000957040
resolver
enst
ENST00000957041
resolver
enst
ENST00000957042
resolver
enst
ENST00000957045
resolver
genesymbol
RRAD
resolver
genesymbol_syn
RAD
resolver
hgnc
HGNC:10446
resolver
uniprot
Q96F39
resolver
uniprot_entry
RAD_HUMAN
resolver
uniprot_sec
Q96F39
resolver
amino_acid_sequence
MTLNGGGSGAGGSRGGGQERERRRGSTPWGPAPPLHRRSMPVDERDLQAALTPGALTAAAAGTGTQGPRLDWPEDSEDSLSSGGSDSDESVYKVLLLGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLVRSREVSVDEGRACAVVFDCKFIETSAALHHNVQALFEGVVRQIRLRRDSKEANARRQAGTRRRESLGKKAKRFLGRIVARNSRKMAFRAKSKSCHDLSVL
uniprot
proteins
function
FUNCTION: May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force (By similarity). May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents (By similarity). Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway (PubMed:18056528). Inhibits phosphorylation and activation of CAMK2D (PubMed:18056528). {ECO:0000250|UniProtKB:O88667, ECO:0000269|PubMed:18056528}.
uniprot
proteins
mass_dalton
33245
uniprot
proteins
protein_family
RGK family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18056528
uniprot
proteins
pubmed
8248782
uniprot
proteins
pubmed
9115241
uniprot
proteins
sequence_length
308
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}.
uniprot
proteins