Frk
entrez
79209
canonical
uniprot
Q62662
canonical
ensembl
ENSRNOG00000000543
resolver
ensembl
ENSRNOG00065003179
resolver
ensp
ENSRNOP00000000653
resolver
ensp
ENSRNOP00065003205
resolver
enst
ENSRNOT00000000653
resolver
enst
ENSRNOT00065004482
resolver
genesymbol
Frk
resolver
genesymbol_syn
Gask
resolver
uniprot_entry
FRK_RAT
resolver
amino_acid_sequence
MGSVCMRLWAYLQPFLPCWSQEADKSVVIENPGAYCPPEANRSQGQYFVALFDYEARTAEDLSFHAGDKLQVLDTSHEGWWLARHLEKKGPGLGQQLQGYIPSNYVAEDRSLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEGVVKHYRIRRLDEGGFFLTRRKTFSTLNEFVNYYTTTSDGLCVKLEKPCLKIQVPTPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFETLHWKLEDYFEPDSSYSDTNNFIN
uniprot
proteins
ec_number
2.7.10.2
uniprot
proteins
function
FUNCTION: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
58166
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
SRC subfamily
uniprot
proteins
protein_family
Tyr protein kinase family
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8167158
uniprot
proteins
pubmed
8760296
uniprot
proteins
sequence_length
506
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery. {ECO:0000250}.
uniprot
proteins