Ank3
entrez
11735
canonical
uniprot
G5E8K5
canonical
ensembl
ENSMUSG00000069601
resolver
ensp
ENSMUSP00000045834
resolver
ensp
ENSMUSP00000061698
resolver
ensp
ENSMUSP00000090087
resolver
ensp
ENSMUSP00000090088
resolver
ensp
ENSMUSP00000090089
resolver
ensp
ENSMUSP00000138285
resolver
ensp
ENSMUSP00000138326
resolver
ensp
ENSMUSP00000138337
resolver
ensp
ENSMUSP00000138347
resolver
ensp
ENSMUSP00000138356
resolver
ensp
ENSMUSP00000138686
resolver
ensp
ENSMUSP00000151906
resolver
enst
ENSMUST00000047061
resolver
enst
ENSMUST00000092431
resolver
enst
ENSMUST00000092432
resolver
enst
ENSMUST00000182439
resolver
enst
ENSMUST00000182992
resolver
enst
ENSMUST00000218680
resolver
genesymbol
Ank3
resolver
uniprot
A0A1W2P812
resolver
uniprot
G3X971
resolver
uniprot
G5E8K2
resolver
uniprot
G5E8K3
resolver
uniprot
G5E8K4
resolver
uniprot
O08866
resolver
uniprot
O08867
resolver
uniprot
Q3TSJ8
resolver
uniprot
Q4U205
resolver
uniprot
Q4U206
resolver
uniprot
Q4U256
resolver
uniprot
Q4U260
resolver
uniprot
Q61305
resolver
uniprot
Q61306
resolver
uniprot
Q61307
resolver
uniprot
Q61308
resolver
uniprot
Q61309
resolver
uniprot
Q61310
resolver
uniprot
Q8CBN3
resolver
uniprot
Q8VC68
resolver
uniprot
S4R2K9
resolver
uniprot_entry
A0A1W2P812_MOUSE
resolver
uniprot_entry
ANK3_MOUSE
resolver
uniprot_entry
G3X971_MOUSE
resolver
uniprot_entry
G5E8K2_MOUSE
resolver
uniprot_entry
G5E8K3_MOUSE
resolver
uniprot_entry
S4R2K9_MOUSE
resolver
uniprot_sec
G5E8K4
resolver
uniprot_sec
O08866
resolver
uniprot_sec
O08867
resolver
uniprot_sec
Q3TSJ8
resolver
uniprot_sec
Q4U205
resolver
uniprot_sec
Q4U206
resolver
uniprot_sec
Q4U256
resolver
uniprot_sec
Q4U260
resolver
uniprot_sec
Q61305
resolver
uniprot_sec
Q61306
resolver
uniprot_sec
Q61307
resolver
uniprot_sec
Q61308
resolver
uniprot_sec
Q61309
resolver
uniprot_sec
Q61310
resolver
uniprot_sec
Q8CBN3
resolver
uniprot_sec
Q8VC68
resolver
amino_acid_sequence
MSEEPKEKPAKPAHRKRKGKKSDANASYLRAARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVVTEEIMTTTTITEKHKMNVPETMNEVLDMSDDEVRKASAPEKLSDGEYISDGEEGDKCTWFKIPKVQEVLVKSEDAITGDTDKYLGPQDLKELGDDSLPAEGYVGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLTFTREFDSDSLRHYSWAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSENGETWKEHQFDSKNEDLAELLNGMDEELDSPEELGTKRICRIITKDFPQYFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDATPNLRLLCSITGGTSPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMAKFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKAEKADRRQSFASLALRKRYSYLTEPSMSPQSPCERTDIRMAIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGHPSFQVELETPMGLYCTPPNPFQQDDHFSDISSIESPFRTPSRLSDGLVPSQGNIEHPTGGPPVVTAEDTSLEDSKMDDSVTVTDPADPLDVDESQLKDLCQSECAQCWASVPGIPNDGRQAEPLRPQTRKVGMSSEQQEKGKSGPDEEVTEDKVKSLFEDIQLEEVEAEEMTEDQGQAMLNRVQRAELAMSSLAGWQNETPSGSLESPAQARRLTGGLLDRLDDSSDQARDSITSYLTGEPGKIEANGNHTAEVIPEAKAKPYFPESQNDIGKQSIKENLKPKTHGCGRTEEPVSPLTAYQKSLEETSKLVIEDAPKPCVPVGMKKMTRTTADGKARLNLQEEEGSTRSEPKQGEGYKVKTKKEIRNVEKKTH
uniprot
proteins
function
FUNCTION: Required for the organization of specialized membrane domains by linking the membrane to the cytoskeleton (By similarity). In neurons, participates in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (By similarity). In skeletal muscle, required for the localization of dystrophin (DMD) and beta-dystroglycan (betaDAG1) to costameres (PubMed:19109891). In rod photoreceptors, required for the transport of cyclic nucleotide-gated (CNG) channel subunits from the inner segment to the sensory cilium outer segment, which is critical for phototransduction and outer segment morphogenesis (PubMed:19299621). Regulates the activity of the potassium channel KCNA1 in response to dietary Mg(2+) levels, contributing to renal Mg(2+) reabsorption (PubMed:23903368). Promotes intracellular adhesion and junctional conductance in myocytes by stabilizing GJA1/CX43 protein abundance and facilitating the localization of PKP2, GJA1/CX43, and SCN5A/Nav1.5 to cell-cell junctions (By similarity). {ECO:0000250|UniProtKB:O70511, ECO:0000250|UniProtKB:Q12955, ECO:0000269|PubMed:19109891, ECO:0000269|PubMed:19299621, ECO:0000269|PubMed:23903368}.
uniprot
proteins
mass_dalton
214062
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18550753
uniprot
proteins
pubmed
19109891
uniprot
proteins
pubmed
19299621
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21223964
uniprot
proteins
pubmed
23903368
uniprot
proteins
pubmed
7615634
uniprot
proteins
pubmed
9060470
uniprot
proteins
sequence_length
1961
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q12955}. Cell projection, axon {ECO:0000250|UniProtKB:O70511}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q12955}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:O70511}. Lysosome {ECO:0000269|PubMed:9060470}. Cell membrane, sarcolemma, T-tubule {ECO:0000250|UniProtKB:O70511}. Photoreceptor outer segment membrane {ECO:0000269|PubMed:19299621}. Cell projection, cilium membrane {ECO:0000269|PubMed:19299621}. Note=In skeletal muscle, localized at costameres and neuromuscular junctions. In bone marrow-derived macrophages, isoforms 2 and 3 are associated with lysosomes. Localized in rod outer segment membranes (PubMed:19299621). Localized to the principle piece of the sperm flagellum and to olfactory cilia (PubMed:19299621). {ECO:0000269|PubMed:19299621}.
uniprot
proteins