Patl1
entrez
225929
canonical
uniprot
Q3TC46
canonical
ensembl
ENSMUSG00000046139
resolver
ensp
ENSMUSP00000060398
resolver
ensp
ENSMUSP00000179190
resolver
enst
ENSMUST00000061618
resolver
genesymbol
Patl1
resolver
uniprot
Q3TD30
resolver
uniprot
Q3U4Q3
resolver
uniprot
Q3UD09
resolver
uniprot
Q6PD49
resolver
uniprot
Q8BN50
resolver
uniprot
Q8C3S7
resolver
uniprot_entry
PATL1_MOUSE
resolver
uniprot_sec
Q3TD30
resolver
uniprot_sec
Q3U4Q3
resolver
uniprot_sec
Q3UD09
resolver
uniprot_sec
Q6PD49
resolver
uniprot_sec
Q8BN50
resolver
uniprot_sec
Q8C3S7
resolver
amino_acid_sequence
MFRYESLEDCPLDEDEDAFQGLGEEDEEIDQFNDDTFGSGAVDDDWQEAHERLAELEEKLPVAADEQTGNGERDEMDLLGDHEENLAERLSKMVIENELEDPAIMRAVQTRPVLQPQPGSLNSSIWDGSEVLRRIRGPLLAQEMPTVSVLEYALPQRPLQGPEDDRDLSERALPRRSTSPIIGSPPVRAVPIGTPPKQMAVPSFNQQILCPKPVHVRPPMPPRYPAPYGERISPNQLCSVPNSSLLGHPFPPNVPPVLSPLQRAQLLGGAQLQPGRMSPSQFARVPGFVGSPLAAMNPKLLQGRVGQMLPPAPSFRAFFSAPPPATPPPQQHPPGPGPHLQNLRPQAPMFRADTTHLHPQHRRLLHQRQLQSRNQHRNLNGTGDRGGHQSSHQDHLRKDPYANLMLQREKDWVSKIQMMQLQSTDPYLDDFYYQNYFEKLEKLSAAEEIQGDGPKKERTKLITPQVAKLEHAYQPVQFEGSLGKLTVSSVNNPRKMIDAVVTSRSEDDETKEKQVRDKRRKTLVIIEKTYSLLLDVEDYERRYLLSLEEERPALMDERKHKICSMYDNLRGKLPGQERPSDDHFVQIMCIRKGKRMVARILPFLSTEQAADILMATARNLPFLIKKDAQDEVLPCLLSPFSLLLYHLPSVTVTSLLQQLMNLPQSASAPAPSNSHLTAVLQNKFGLSLLLILLSRGEDLQSSDPAIESTQNNQWTEVMFMATRELLRIPQAALAKPISIPTNLVSLFSRYVDRQKLNLLETKLQLVQGIR
uniprot
proteins
function
FUNCTION: RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. {ECO:0000250|UniProtKB:Q86TB9}.
uniprot
proteins
mass_dalton
86770
uniprot
proteins
protein_family
PAT1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
770
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, P-body {ECO:0000250|UniProtKB:Q86TB9}. Nucleus {ECO:0000250|UniProtKB:Q86TB9}. Nucleus, PML body {ECO:0000250|UniProtKB:Q86TB9}. Nucleus speckle {ECO:0000250|UniProtKB:Q86TB9}. Note=Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Enriched in splicing speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus. {ECO:0000250|UniProtKB:Q86TB9}.
uniprot
proteins