Slc35g1
entrez
240660
canonical
uniprot
Q8BY79
canonical
ensembl
ENSMUSG00000044026
resolver
ensp
ENSMUSP00000061282
resolver
enst
ENSMUST00000054098
resolver
genesymbol
Slc35g1
resolver
genesymbol_syn
Tmem20
resolver
uniprot
B2RPY9
resolver
uniprot_entry
S35G1_MOUSE
resolver
uniprot_sec
B2RPY9
resolver
activity_regulation
ACTIVITY REGULATION: Citrate transport is inhibited by chloride ions at physiologically extracellular concentrations. {ECO:0000250|UniProtKB:Q2M3R5}.
uniprot
proteins
amino_acid_sequence
MGPPESAAELAAEAVELREPELQLADPASPGEEHVDVEAEGAPGRGRCWPCGAWACGSRGEPEAKKKAPCPGLGLFYTVLSAFLFSVASLFVKKVQGVHAVEISAFRCVVQMLVIIPCLIYRKTGFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPPFIFGSDTSGMRESYSEHIKGTFAAIGHAVLAAITLVILRKMGKSVDYFLSIWYYVILGLPEAIIILFVIGEWSLPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQGSK
uniprot
proteins
function
FUNCTION: Chloride-sensitive citrate transporter localized on the basolateral membrane of enterocytes that mediates efflux of citrate into the bloodstream. May also play a role in intracellular calcium sensing and homeostasis by acting as a negative regulator of plasma membrane calcium-transporting ATPases, thereby preventing calcium efflux from the cell. {ECO:0000250|UniProtKB:Q2M3R5}.
uniprot
proteins
mass_dalton
40217
uniprot
proteins
protein_family
SLC35G solute transporter family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
368
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000250|UniProtKB:Q2M3R5}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q2M3R5}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q2M3R5}; Multi-pass membrane protein {ECO:0000255}. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane. {ECO:0000250|UniProtKB:Q2M3R5}.
uniprot
proteins
transmembrane_region
TRANSMEM 72..92; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 134..154; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 161..181; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 256..276; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 289..309; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 316..336; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 340..360; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins