RASSF2
entrez
9770
canonical
uniprot
P50749
canonical
ensembl
ENSG00000101265
resolver
ensp
ENSP00000368684
resolver
ensp
ENSP00000368710
resolver
ensp
ENSP00000542703
resolver
ensp
ENSP00000542704
resolver
ensp
ENSP00000542706
resolver
ensp
ENSP00000608008
resolver
ensp
ENSP00000639859
resolver
ensp
ENSP00000639861
resolver
genesymbol
RASSF2
resolver
genesymbol_syn
CENP-34
resolver
genesymbol_syn
KIAA0168
resolver
hgnc
HGNC:9883
resolver
uniprot
A6NIX9
resolver
uniprot
A8K5Z3
resolver
uniprot
Q17S06
resolver
uniprot
Q53HD0
resolver
uniprot
Q6AHZ2
resolver
uniprot
Q8IZA5
resolver
uniprot_entry
RASF2_HUMAN
resolver
uniprot_sec
A6NIX9
resolver
uniprot_sec
A8K5Z3
resolver
uniprot_sec
Q17S06
resolver
uniprot_sec
Q53HD0
resolver
uniprot_sec
Q6AHZ2
resolver
uniprot_sec
Q8IZA5
resolver
amino_acid_sequence
MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISWGLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQMPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKYTVLRLMIRQRLEEIAETPATI
uniprot
proteins
function
FUNCTION: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. {ECO:0000269|PubMed:12732644, ECO:0000269|PubMed:16012945, ECO:0000269|PubMed:19525978}.
uniprot
proteins
mass_dalton
37790
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by STK3/MST2 and STK4/MST1. {ECO:0000269|PubMed:19525978}.
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12732644
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15569673
uniprot
proteins
pubmed
16012945
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19525978
uniprot
proteins
pubmed
20813266
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
8724849
uniprot
proteins
sequence_length
326
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}. Note=Translocates to the cytoplasm in the presence of STK3/MST2 and STK4/MST1.
uniprot
proteins