Slc26a11
entrez
268512
canonical
uniprot
Q80ZD3
canonical
ensembl
ENSMUSG00000039908
resolver
ensp
ENSMUSP00000050999
resolver
ensp
ENSMUSP00000299034
resolver
genesymbol
Slc26a11
resolver
uniprot
B2RQF3
resolver
uniprot
Q8BTP1
resolver
uniprot
Q8BWL3
resolver
uniprot
Q8CHW8
resolver
uniprot_entry
S2611_MOUSE
resolver
uniprot_sec
B2RQF3
resolver
uniprot_sec
Q8BTP1
resolver
uniprot_sec
Q8BWL3
resolver
uniprot_sec
Q8CHW8
resolver
amino_acid_sequence
MAPDTCCCSATALRRRLPVLAWVPDYSLQWLRLDFIAGLSVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQIKNLLGLQKIPRQFFLQVYHTFLHIGETRVGDAVLGLASMLLLLVLKCMREHMPPPHPEMPLAVKFSRGLVWTVTTARNALVVSSAALIAYAFEVTGSHPFVLTGKIAEGLPPVRIPPFSVTRDNKTISFSEMVQDMGAGLAVVPLMGLLESIAVAKSFASQNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGALVLLSLNYLTSLFSYIPKSALAAVIITAVTPLFDVKIFRSLWRVQRLDLLPLCVTFLLSFWEIQYGILAGSLVSLLILLHSVARPKTQVSEGQIFVLQPASGLYFPAIDALREAITNRALEASPPRSAVLECTHISSVDYTVIVGLGELLEDFQKKGVALAFVGLQVPVLRTLLAADLKGFRYFTTLEEAEKFLQQEPGTEPNSIHEDAVPEQRSSLLKSPSGP
uniprot
proteins
function
FUNCTION: Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport (By similarity). Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC) (By similarity). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion (PubMed:21716257). May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum (PubMed:23733100, PubMed:27390771). {ECO:0000250|UniProtKB:G3C7W6, ECO:0000250|UniProtKB:Q86WA9, ECO:0000269|PubMed:21716257, ECO:0000269|PubMed:23733100, ECO:0000269|PubMed:27390771}.
uniprot
proteins
mass_dalton
64109
uniprot
proteins
protein_family
SLC26A/SulP transporter (TC 2.A.53) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21716257
uniprot
proteins
pubmed
23733100
uniprot
proteins
pubmed
27390771
uniprot
proteins
sequence_length
593
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23733100}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000250|UniProtKB:Q86WA9}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:21716257}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:21716257}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 35..55; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 57..77; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 83..100; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 107..127; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 177..197; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 234..254; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 325..345; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 362..382; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 384..404; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 418..438; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins