Ndor1
entrez
78797
canonical
uniprot
A2AI05
canonical
ensembl
ENSMUSG00000006471
resolver
ensembl
ENSMUSG00000115074
resolver
ensp
ENSMUSP00000097903
resolver
ensp
ENSMUSP00000109989
resolver
ensp
ENSMUSP00000154261
resolver
ensp
ENSMUSP00000171831
resolver
ensp
ENSMUSP00000171836
resolver
enst
ENSMUST00000228052
resolver
genesymbol
Ndor1
resolver
uniprot
A0A2I3BQN1
resolver
uniprot
Q3TQZ6
resolver
uniprot
Q80WC5
resolver
uniprot_entry
A0A2I3BQN1_MOUSE
resolver
uniprot_entry
NDOR1_MOUSE
resolver
uniprot_sec
Q3TQZ6
resolver
uniprot_sec
Q80WC5
resolver
amino_acid_sequence
MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPPCLGDDQHELGPDAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFDITDSNISFAAGDVVFILPSNSEAHTQQFCQVLCLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALEREKLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGNFLFFGCRQRDQDFYWQTEWQKLEQKGWLTLVTAFSREQEQKVYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYLPTDVSEALMSIFQEEGRLSTADASAYLARLQQTLRFQTETWA
uniprot
proteins
ec_number
1.18.1.-
uniprot
proteins
function
FUNCTION: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair (By similarity). In vitro can fully activate methionine synthase/MTR in the presence of soluble cytochrome b5/CYB5A (By similarity). {ECO:0000250|UniProtKB:Q9UHB4, ECO:0000255|HAMAP-Rule:MF_03178}.
uniprot
proteins
mass_dalton
67183
uniprot
proteins
protein_family
NADPH-dependent diflavin oxidoreductase NDOR1 family; Flavodoxin family; Flavoprotein pyridine nucleotide cytochrome reductase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
598
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000255|HAMAP-Rule:MF_03178}. Note=Concentrated in perinuclear structure. {ECO:0000255|HAMAP-Rule:MF_03178}.
uniprot
proteins