ANKS1B
entrez
56899
canonical
uniprot
Q7Z6G8
canonical
ensembl
ENSG00000185046
resolver
ensp
ENSP00000331256
resolver
ensp
ENSP00000345510
resolver
ensp
ENSP00000447312
resolver
ensp
ENSP00000447839
resolver
ensp
ENSP00000447999
resolver
ensp
ENSP00000448203
resolver
ensp
ENSP00000448205
resolver
ensp
ENSP00000448512
resolver
ensp
ENSP00000448744
resolver
ensp
ENSP00000448993
resolver
ensp
ENSP00000449629
resolver
ensp
ENSP00000450015
resolver
ensp
ENSP00000508105
resolver
enst
ENST00000333732
resolver
enst
ENST00000683438
resolver
genesymbol
ANKS1B
resolver
hgnc
HGNC:24600
resolver
uniprot
A0A804HKX1
resolver
uniprot
A5PKY5
resolver
uniprot
A7E259
resolver
uniprot
A8K153
resolver
uniprot
A8MSN4
resolver
uniprot
B1VKB5
resolver
uniprot
B4DFP6
resolver
uniprot
B4DH98
resolver
uniprot
B7Z9I9
resolver
uniprot
F8VPM3
resolver
uniprot
F8VR14
resolver
uniprot
F8VZR9
resolver
uniprot
F8WC27
resolver
uniprot
Q5XLJ0
resolver
uniprot
Q6IVB5
resolver
uniprot
Q6NUS4
resolver
uniprot
Q6V0K8
resolver
uniprot
Q7Z6G6
resolver
uniprot
Q7Z6G7
resolver
uniprot
Q8TAP3
resolver
uniprot
Q9NRX7
resolver
uniprot
Q9Y5K9
resolver
uniprot_entry
A0A804HKX1_HUMAN
resolver
uniprot_entry
ANS1B_HUMAN
resolver
uniprot_entry
B1VKB5_HUMAN
resolver
uniprot_entry
B7Z9I9_HUMAN
resolver
uniprot_entry
F8VR14_HUMAN
resolver
uniprot_entry
Q6V0K8_HUMAN
resolver
uniprot_sec
A5PKY5
resolver
uniprot_sec
A7E259
resolver
uniprot_sec
A8K153
resolver
uniprot_sec
A8MSN4
resolver
uniprot_sec
B4DFP6
resolver
uniprot_sec
B4DH98
resolver
uniprot_sec
F8VPM3
resolver
uniprot_sec
F8VZR9
resolver
uniprot_sec
F8WC27
resolver
uniprot_sec
Q5XLJ0
resolver
uniprot_sec
Q6IVB5
resolver
uniprot_sec
Q6NUS4
resolver
uniprot_sec
Q7Z6G6
resolver
uniprot_sec
Q7Z6G7
resolver
uniprot_sec
Q8TAP3
resolver
uniprot_sec
Q9NRX7
resolver
uniprot_sec
Q9Y5K9
resolver
amino_acid_sequence
MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHPSQKSLQIATLLQEYLEGVGRSTVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHTISDHYLDNLSKISEEELGKNGSQSVRTSSTINLSPGEVEEEDDDENTCGPSGLWEALTPCNGCRNLGFPMLAQESYPKKRNYTMEIVPSASLDTFPSENENFLCDLMDTAVTKKPCSLEIARAPSPRTDNASEVAVTTPGTSNHRNSSTGPTPDCSPPSPDTALKNIVKVIRPQPKQRTSIVSSLDFHRMNHNQEYFEINTSTGCTSFTASPPASPPTSSVGTTEVKNEGTNHTDDLSRQDDNDPPKEYDPGQFAGLLHGSSPACESPENPFHLYGKREQCEKGQDEVSLANSPLPFKQSPIENNSEPLVKKIKPKVVSRTIFHKKSNQLENHTIVGTRSTRSGSRNGDQWVMNAGGFVERACTLGRIRSLPKALIDMHLSKSVSKSDSDLIAYPSNEKTSRVNWSESSTAEHSSKGNSERTPSFTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
uniprot
proteins
function
FUNCTION: Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells.; FUNCTION: Isoform 3 can regulate global protein synthesis by altering nucleolar numbers. {ECO:0000250, ECO:0000269|PubMed:15347684, ECO:0000269|PubMed:15862129}.; FUNCTION: Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing.
uniprot
proteins
mass_dalton
138066
uniprot
proteins
post_translational_modification
PTM: Isoform 3 nuclear translocation requires an NMDAR-dependent proteolytic cleavage. {ECO:0000250}.
uniprot
proteins
pubmed
10490826
uniprot
proteins
pubmed
10931946
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15004329
uniprot
proteins
pubmed
15347684
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15862129
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
16769578
uniprot
proteins
pubmed
17875921
uniprot
proteins
pubmed
19666031
uniprot
proteins
sequence_length
1248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15004329, ECO:0000269|PubMed:15347684, ECO:0000269|PubMed:15862129, ECO:0000269|PubMed:19666031}.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 3]: Postsynaptic density. Cell projection, dendritic spine. Nucleus. Nucleus, Cajal body. Note=The synaptic localization requires DLG4 interaction. Translocation to the nucleus in response to stimulation of NMDA receptors (NMDARs) in a calcium-independent manner (By similarity). {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 4]: Nucleus. Note=The interaction with APP causes its partial exclusion from the nucleus, when APP is overexpressed.; SUBCELLULAR LOCATION: [Isoform 6]: Nucleus.
uniprot
proteins