Slc10a7
entrez
76775
canonical
uniprot
Q5PT53
canonical
ensembl
ENSMUSG00000031684
resolver
ensp
ENSMUSP00000034111
resolver
ensp
ENSMUSP00000147659
resolver
ensp
ENSMUSP00000148199
resolver
ensp
ENSMUSP00000200778
resolver
ensp
ENSMUSP00000200783
resolver
ensp
ENSMUSP00000335811
resolver
ensp
ENSMUSP00000335812
resolver
genesymbol
Slc10a7
resolver
genesymbol_syn
P7
resolver
uniprot
Q5PT51
resolver
uniprot
Q8BV58
resolver
uniprot
Q8BYD0
resolver
uniprot
Q9CWD6
resolver
uniprot_entry
NTCP7_MOUSE
resolver
uniprot_sec
Q5PT51
resolver
uniprot_sec
Q8BV58
resolver
uniprot_sec
Q8BYD0
resolver
uniprot_sec
Q9CWD6
resolver
amino_acid_sequence
MRLLERARKEWFMVGIVVAIGAAKLEPSVGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLRLHLFIQIFTLAFFPAAIWLFLQLLSVTSINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPVLLLLFLGSSSSVPFTSIFSQLFMTVVVPLVIGQIVRRYIKDWLERKKPPFGVVSSSVLLMIIYTTFCDTFSNPNIDLDKFSLILILFIIVSVQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV
uniprot
proteins
function
FUNCTION: Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization (PubMed:30082715). Also involved in the regulation of cellular calcium homeostasis (By similarity). Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate). {ECO:0000250|UniProtKB:Q0GE19, ECO:0000269|PubMed:30082715}.
uniprot
proteins
mass_dalton
37256
uniprot
proteins
protein_family
Bile acid:sodium symporter (BASS) (TC 2.A.28) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17628207
uniprot
proteins
pubmed
30082715
uniprot
proteins
pubmed
31191616
uniprot
proteins
sequence_length
340
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q0GE19}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q0GE19}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q0GE19}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q0GE19}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q0GE19}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 38..58; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 72..92; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..159; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 164..184; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 235..255; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 271..291; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 299..319; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins