Mpp3
entrez
114202
canonical
uniprot
O88954
canonical
ensembl
ENSRNOG00000033653
resolver
ensp
ENSRNOP00000028264
resolver
enst
ENSRNOT00000028264
resolver
genesymbol
Mpp3
resolver
genesymbol_syn
Dlg3
resolver
genesymbol_syn
Dusp3
resolver
uniprot
A6HJG0
resolver
uniprot_entry
MPP3_RAT
resolver
uniprot_sec
A6HJG0
resolver
amino_acid_sequence
MPVLSEDSGLHETLALLTSQLRPDSNHREEMGFLRDVFSEKSLGYLMKIHEKLRYYERQSPTPVLHSAMALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGITVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKESKVFMRALFHYDPREDRAIPCQEAGLPFQQRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTIPSPQNLRKPLYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLTGSQEVKVPVGAESQVLLTYEEVARYQHQPGERSRLVVLIGSLGAHLHELKQRVVAEDPQHFGVAVPHTTRPRKSHEREGVEYHFVSKQAFEADIQHNKFLEHGEHKENLYGTSLEAIQTVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKPAIQEKRKTPPVSPDSEDPATPLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQSVCSQLRAVIESLSKDTYWVPISWVR
uniprot
proteins
function
FUNCTION: Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K) (By similarity). Stabilizes HTR2C at the plasma membrane and prevents its desensitization. May participates in the maintenance of adherens junctions (By similarity). {ECO:0000250|UniProtKB:O88910, ECO:0000250|UniProtKB:Q13368}.
uniprot
proteins
mass_dalton
66589
uniprot
proteins
protein_family
MAGUK family
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9753324
uniprot
proteins
sequence_length
585
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:O88910}. Cell membrane {ECO:0000250|UniProtKB:Q13368}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q13368}. Note=Localized in apical villi of Mueller glia cells. Localized at the apical membrane in the developing cortex and colocalized with apical proteins and adherens junction proteins (By similarity). Localized at the outer limiting membrane (OLM), and outer plexiform (OPL) of retina (By similarity). {ECO:0000250|UniProtKB:O88910, ECO:0000250|UniProtKB:Q13368}.
uniprot
proteins