Gpr61
entrez
229714
canonical
uniprot
Q8C010
canonical
ensembl
ENSMUSG00000046793
resolver
ensp
ENSMUSP00000055557
resolver
ensp
ENSMUSP00000111988
resolver
enst
ENSMUST00000062028
resolver
enst
ENSMUST00000116284
resolver
genesymbol
Gpr61
resolver
uniprot
Q3UZR6
resolver
uniprot_entry
GPR61_MOUSE
resolver
uniprot_sec
Q3UZR6
resolver
amino_acid_sequence
MESSPIPQSSGNSSTLGRALQTPGPSTASGVPELGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVYWEEGAPSVNPGCSLQWSHSAYCQLFVVVFAVLYFLLPLILIFVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAHQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISAGQVENVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKAAPEEELRLPSREGSIEENFLQFLQGTSENWVSRPLPSPKREPPPVVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAPSPRLES
uniprot
proteins
function
FUNCTION: Orphan G protein-coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). May be involved in the regulation of food intake and body weight (PubMed:21971119). {ECO:0000250|UniProtKB:Q9BZJ8, ECO:0000269|PubMed:21971119}.
uniprot
proteins
mass_dalton
49382
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21971119
uniprot
proteins
pubmed
28912303
uniprot
proteins
sequence_length
449
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9BZJ8}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000250|UniProtKB:Q9BZJ8}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome (By similarity). {ECO:0000250|UniProtKB:Q9BZJ8}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..67; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 76..98; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 113..135; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 156..178; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 207..229; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 288..310; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 325..344; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins