RDM1
entrez
201299
canonical
uniprot
Q8NG50
canonical
ensembl
ENSG00000276432
resolver
ensembl
ENSG00000278023
resolver
ensp
ENSP00000478915
resolver
ensp
ENSP00000479310
resolver
ensp
ENSP00000479622
resolver
ensp
ENSP00000480131
resolver
ensp
ENSP00000482288
resolver
ensp
ENSP00000483387
resolver
ensp
ENSP00000483549
resolver
ensp
ENSP00000483933
resolver
ensp
ENSP00000747993
resolver
genesymbol
RDM1
resolver
genesymbol_syn
RAD52B
resolver
hgnc
HGNC:19950
resolver
uniprot
A0JP55
resolver
uniprot
A8MV46
resolver
uniprot
A8MY68
resolver
uniprot
A8MZ92
resolver
uniprot
A8RCS5
resolver
uniprot
A8RCT0
resolver
uniprot
A8RCT5
resolver
uniprot
A8RCT8
resolver
uniprot
A8RCU3
resolver
uniprot
A8RCU8
resolver
uniprot
A8RCW0
resolver
uniprot
A8RCW5
resolver
uniprot_entry
RDM1_HUMAN
resolver
uniprot_sec
A0JP55
resolver
uniprot_sec
A8MV46
resolver
uniprot_sec
A8MY68
resolver
uniprot_sec
A8MZ92
resolver
uniprot_sec
A8RCS5
resolver
uniprot_sec
A8RCT0
resolver
uniprot_sec
A8RCT5
resolver
uniprot_sec
A8RCT8
resolver
uniprot_sec
A8RCU3
resolver
uniprot_sec
A8RCU8
resolver
uniprot_sec
A8RCW0
resolver
uniprot_sec
A8RCW5
resolver
amino_acid_sequence
MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVEEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGVRCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD
uniprot
proteins
function
FUNCTION: May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. {ECO:0000269|PubMed:15611051}.
uniprot
proteins
mass_dalton
31970
uniprot
proteins
mutagenesis
MUTAGEN 98..100; /note="RHK->AAA: Reduces its nuclear and nucleolar accumulation. Increases its cytoplasmic accumulation."; /evidence="ECO:0000269|PubMed:17905820"; MUTAGEN 120..122; /note="YYF->AAA: Does not affect its subcellular distribution."; /evidence="ECO:0000269|PubMed:17905820
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15611051
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
17905820
uniprot
proteins
sequence_length
284
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17905820}. Cytoplasm {ECO:0000269|PubMed:17905820}. Nucleus, nucleolus {ECO:0000269|PubMed:17905820}. Note=Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Nucleus, PML body. Nucleus, Cajal body. Note=Isoform 1 is predominantly cytoplasmic. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress.
uniprot
proteins