POU2F1
entrez
5451
canonical
uniprot
P14859
canonical
ensembl
ENSG00000143190
resolver
ensp
ENSP00000356836
resolver
ensp
ENSP00000356840
resolver
ensp
ENSP00000401217
resolver
ensp
ENSP00000415993
resolver
ensp
ENSP00000441285
resolver
genesymbol
POU2F1
resolver
genesymbol_syn
OCT1
resolver
genesymbol_syn
OTF1
resolver
hgnc
HGNC:9212
resolver
uniprot
B1AL91
resolver
uniprot
B1AL93
resolver
uniprot
B4E029
resolver
uniprot
J3KP77
resolver
uniprot
Q5TBT7
resolver
uniprot
Q6PK46
resolver
uniprot
Q8NEU9
resolver
uniprot
Q9BPV1
resolver
uniprot_entry
PO2F1_HUMAN
resolver
uniprot_sec
B1AL91
resolver
uniprot_sec
B1AL93
resolver
uniprot_sec
B4E029
resolver
uniprot_sec
J3KP77
resolver
uniprot_sec
Q5TBT7
resolver
uniprot_sec
Q6PK46
resolver
uniprot_sec
Q8NEU9
resolver
uniprot_sec
Q9BPV1
resolver
amino_acid_sequence
MNNPSETSKPSMESGDGNTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQPSVQAAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSAATTLTVSPVLPLTSAAVTNLSVTGTSDTTSNNTATVISTAPPASSAVTSPSLSPSPSASASTSEASSASETSTTQTTSTPLSSPLGTSQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPSLMAPSQFAAGGALLSLNPGTLSGALSPALMSNSTLATIQALASGGSLPITSLDATGNLVFANAGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASAGNSAPVASLHATSTSAESIQNSLFTVASASGAASTTTTASKAQ
uniprot
proteins
function
FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. {ECO:0000269|PubMed:10480874, ECO:0000269|PubMed:1684878, ECO:0000269|PubMed:7859290}.; FUNCTION: (Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. {ECO:0000305|PubMed:12826401}.
uniprot
proteins
mass_dalton
76472
uniprot
proteins
mutagenesis
MUTAGEN 385; /note="S->A: Loss of inhibition of DNA binding."; /evidence="ECO:0000269|PubMed:1684878
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PRKDC. {ECO:0000269|PubMed:14612514, ECO:0000269|PubMed:1684878}.
uniprot
proteins
protein_family
Class-2 subfamily
uniprot
proteins
protein_family
POU transcription factor family
uniprot
proteins
pubmed
10480874
uniprot
proteins
pubmed
10629049
uniprot
proteins
pubmed
12663137
uniprot
proteins
pubmed
12826401
uniprot
proteins
pubmed
14612514
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
1684878
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17537858
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2905684
uniprot
proteins
pubmed
7663141
uniprot
proteins
pubmed
7859290
uniprot
proteins
pubmed
8156594
uniprot
proteins
pubmed
8462099
uniprot
proteins
pubmed
8479524
uniprot
proteins
sequence_length
743
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins