SIGLEC9
entrez
27180
canonical
uniprot
Q9Y336
canonical
ensembl
ENSG00000129450
resolver
ensp
ENSP00000250360
resolver
ensp
ENSP00000413861
resolver
ensp
ENSP00000520938
resolver
enst
ENST00000850849
resolver
genesymbol
SIGLEC9
resolver
hgnc
HGNC:10878
resolver
uniprot
A0ABJ7H890
resolver
uniprot
Q6GTU4
resolver
uniprot
Q9BYI9
resolver
uniprot_entry
A0ABJ7H890_HUMAN
resolver
uniprot_entry
SIGL9_HUMAN
resolver
uniprot_sec
Q6GTU4
resolver
uniprot_sec
Q9BYI9
resolver
amino_acid_sequence
MLLLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGYWFREGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFRMEKGSIKWNYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWIGTSVSPLDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQSKATSGVTQGVVGGAGATALVFLSFCVIFVVVRSCRKKSARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARSSVGEGELQYASLSFQMVKPWDSRGQEATDTEYSEIKIHR
uniprot
proteins
function
FUNCTION: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
uniprot
proteins
mass_dalton
50082
uniprot
proteins
mutagenesis
MUTAGEN 120; /note="R->K: Loss of sialic acid binding."; /evidence="ECO:0000269|PubMed:10801860
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
protein_family
SIGLEC (sialic acid binding Ig-like lectin) family
uniprot
proteins
pubmed
10801860
uniprot
proteins
pubmed
10801862
uniprot
proteins
pubmed
10903842
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
463
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 349..369; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins