Gpat4
entrez
102247
canonical
uniprot
Q8K2C8
canonical
ensembl
ENSMUSG00000031545
resolver
ensp
ENSMUSP00000127325
resolver
ensp
ENSMUSP00000313824
resolver
enst
ENSMUST00000167004
resolver
genesymbol
Gpat4
resolver
genesymbol_syn
Agpat6
resolver
genesymbol_syn
Tsarg7
resolver
uniprot
Q3TF78
resolver
uniprot
Q5QHR4
resolver
uniprot_entry
GPAT4_MOUSE
resolver
uniprot_sec
Q3TF78
resolver
uniprot_sec
Q5QHR4
resolver
amino_acid_sequence
MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKTLLKIFAWATLRMERGAKERNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDKTPEFELSDIFYFCRKGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTILWGLGVLIRYCFLLPLRIALAFTGIGLLVVGTTMVGYLPNGRFKEFLSKHVHLMCYRICVRALTAIITYHNRKNRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREKDEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDTFKEEQQKLYSKMIVGNHEDRSRS
uniprot
proteins
ec_number
2.3.1.15
uniprot
proteins
function
FUNCTION: Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (PubMed:18238778). Active against both saturated and unsaturated long-chain fatty acyl-CoAs (By similarity). Protects cells against lipotoxicity (By similarity). {ECO:0000250|UniProtKB:Q86UL3, ECO:0000269|PubMed:18238778}.
uniprot
proteins
mass_dalton
52181
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
uniprot
proteins
protein_family
1-acyl-sn-glycerol-3-phosphate acyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15944755
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18238778
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
456
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q86UL3}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 156..176; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 180..200; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins