Flywch1
entrez
224613
canonical
uniprot
Q8CI03
canonical
ensembl
ENSMUSG00000040097
resolver
ensp
ENSMUSP00000083505
resolver
ensp
ENSMUSP00000154618
resolver
genesymbol
Flywch1
resolver
genesymbol_syn
Kiaa1552
resolver
uniprot
E9QKQ2
resolver
uniprot
Q3TH83
resolver
uniprot
Q6ZPN0
resolver
uniprot
Q8C792
resolver
uniprot_entry
FWCH1_MOUSE
resolver
uniprot_sec
E9QKQ2
resolver
uniprot_sec
Q3TH83
resolver
uniprot_sec
Q6ZPN0
resolver
uniprot_sec
Q8C792
resolver
amino_acid_sequence
MPLPEPSEQDCESLRAGQEPSVGARKPQESSNLVPARDKERPKPTDVASQETSSTATLPNNTLQVAPVKKQGRIIHRKRSRVDAVPPQPLEFLKTPFGGRLLVHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTEMRDHCHPPEKEGLDRKKRHRGRPPSSALPEGAEVQEDEVSLWLYPVEPEPTPQPSIETPEEEQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGGKVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDIEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDSLLQGVDSLFYRRGQGTLTLSRSKSKSKSKSRSKSKSKSRSRSRKRAKKQQESSQEPPEEDQDVDPRGPEFLKTPLGGNFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRSHCHPPDLLGLETLRQREKRPGPSQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGDKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGGLEALRQRENFPNLTHWEGPEPLQPLEFLRTSLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHPPDLAGLEALRQREKAPSAAKKKKKKKKKKKGIH
uniprot
proteins
function
FUNCTION: Transcription cofactor. Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding. May play a role in DNA-damage response signaling. Binds specifically to DNA sequences at peri-centromeric chromatin loci. {ECO:0000250|UniProtKB:Q4VC44}.
uniprot
proteins
mass_dalton
77096
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
673
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q4VC44}. Chromosome, centromere {ECO:0000250|UniProtKB:Q4VC44}. Note=Localized to peri-centromeric, H3K9me3-marked heterochromatin. {ECO:0000250|UniProtKB:Q4VC44}.
uniprot
proteins