PTH2R
entrez
5746
canonical
uniprot
P49190
canonical
ensembl
ENSG00000144407
resolver
ensp
ENSP00000272847
resolver
ensp
ENSP00000482485
resolver
enst
ENST00000272847
resolver
enst
ENST00000617735
resolver
genesymbol
PTH2R
resolver
genesymbol_syn
PTHR2
resolver
hgnc
HGNC:9609
resolver
uniprot
A0A087WZA2
resolver
uniprot
B4DFN8
resolver
uniprot
Q8N429
resolver
uniprot_entry
A0A087WZA2_HUMAN
resolver
uniprot_entry
B4DFN8_HUMAN
resolver
uniprot_entry
PTH2R_HUMAN
resolver
uniprot_sec
Q8N429
resolver
amino_acid_sequence
MAGLGASLHVWGWLMLGSCLLARAQLDSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNLSVDWKRTPPCGSRRCGSVLTTVTHSTSSQSQVAASTRMVLISGKAAKIASRQPDSHITLPGYVWSNSEQDCLPHSFHEETKEDSGRQGDDILMEKPSRPMESNPDTEGCQGETEDVL
uniprot
proteins
function
FUNCTION: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
62236
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
11861531
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7797535
uniprot
proteins
pubmed
8921382
uniprot
proteins
sequence_length
550
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 146..169; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 177..196; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 238..260; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 276..297; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 317..337; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 365..383; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 395..417; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins