F7
entrez
14068
canonical
uniprot
P70375
canonical
ensembl
ENSMUSG00000031443
resolver
ensp
ENSMUSP00000033820
resolver
enst
ENSMUST00000033820
resolver
genesymbol
F7
resolver
genesymbol_syn
Cf7
resolver
uniprot
Q542C2
resolver
uniprot
Q61109
resolver
uniprot_entry
FA7_MOUSE
resolver
uniprot_entry
Q542C2_MOUSE
resolver
uniprot_sec
Q61109
resolver
amino_acid_sequence
MVPQAHGLLLLCFLLQLQGPLGTAVFITQEEAHGVLHRQRRANSLLEELWPGSLERECNEEQCSFEEAREIFKSPERTKQFWIVYSDGDQCASNPCQNGGTCQDHLKSYVCFCLLDFEGRNCEKSKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYTLQPDEVSCKPKVEYPCGRIPVVEKRNSSSRQGRIVGGNVCPKGECPWQAVLKINGLLLCGAVLLDARWIVTAAHCFDNIRYWGNITVVMGEHDFSEKDGDEQVRRVTQVIMPDKYIRGKINHDIALLRLHRPVTFTDYVVPLCLPEKSFSENTLARIRFSRVSGWGQLLDRGATALELMSIEVPRLMTQDCLEHAKHSSNTPKITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVRHMDSKLQVGVFRLPLL
uniprot
proteins
ec_number
3.4.21.21
uniprot
proteins
function
FUNCTION: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
50276
uniprot
proteins
post_translational_modification
PTM: The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. {ECO:0000250}.; PTM: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. {ECO:0000250}.; PTM: Can be either O-glucosylated or O-xylosylated at Ser-93 by POGLUT1. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18316400
uniprot
proteins
pubmed
8701412
uniprot
proteins
pubmed
8972017
uniprot
proteins
sequence_length
446
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins