Mpped2
entrez
362185
canonical
uniprot
B1WBP0
canonical
ensembl
ENSRNOG00000004863
resolver
ensembl
ENSRNOG00055022961
resolver
ensembl
ENSRNOG00060002300
resolver
ensembl
ENSRNOG00065015563
resolver
ensp
ENSRNOP00000062716
resolver
ensp
ENSRNOP00055032028
resolver
ensp
ENSRNOP00060002518
resolver
ensp
ENSRNOP00065020336
resolver
enst
ENSRNOT00000065168
resolver
enst
ENSRNOT00055039453
resolver
enst
ENSRNOT00060003630
resolver
enst
ENSRNOT00065025850
resolver
genesymbol
Mpped2
resolver
uniprot
Q8CFG1
resolver
uniprot_entry
MPPD2_RAT
resolver
uniprot_sec
Q8CFG1
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by nmolar levels of AMP and GMP. {ECO:0000269|PubMed:21824479}.
uniprot
proteins
amino_acid_sequence
MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQGS
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Displays low metallophosphoesterase activity (in vitro) (PubMed:19004815, PubMed:21824479). May play a role in the development of the nervous system (Probable). {ECO:0000269|PubMed:19004815, ECO:0000269|PubMed:21824479, ECO:0000305}.
uniprot
proteins
mass_dalton
33336
uniprot
proteins
mutagenesis
MUTAGEN 65; /note="D->A: Loss of phosphodiesterase activity."; /evidence="ECO:0000269|PubMed:19004815"; MUTAGEN 67; /note="H->A,R: Loss of phosphodiesterase activity. Disrupts metal cofactor binding."; /evidence="ECO:0000269|PubMed:19004815"; MUTAGEN 86; /note="D->A: Loss of phosphodiesterase activity."; /evidence="ECO:0000269|PubMed:19004815"; MUTAGEN 117; /note="N->A: Loss of phosphodiesterase activity."; /evidence="ECO:0000269|PubMed:19004815"; MUTAGEN 118; /note="H->A: Loss of phosphodiesterase activity."; /evidence="ECO:0000269|PubMed:19004815"; MUTAGEN 183; /note="F->A: Decreased affinity for manganese. Decreased inhibition by AMP and GMP."; /evidence="ECO:0000269|PubMed:19004815, ECO:0000269|PubMed:21824479"; MUTAGEN 252; /note="G->H: Increased affinity for manganese. Decreased inhibition by AMP and GMP."; /evidence="ECO:0000269|PubMed:19004815, ECO:0000269|PubMed:21824479
uniprot
proteins
protein_family
UPF0046 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19004815
uniprot
proteins
pubmed
21824479
uniprot
proteins
sequence_length
294
uniprot
proteins