Septin14
entrez
74222
canonical
uniprot
Q9DA97
canonical
ensembl
ENSMUSG00000034219
resolver
ensp
ENSMUSP00000138729
resolver
enst
ENSMUST00000182386
resolver
genesymbol
Septin14
resolver
genesymbol_syn
Sept14
resolver
uniprot
E9QMM2
resolver
uniprot
S4R2P6
resolver
uniprot_entry
S4R2P6_MOUSE
resolver
uniprot_entry
SEP14_MOUSE
resolver
uniprot_sec
E9QMM2
resolver
amino_acid_sequence
MAEKPTNTSVPIPGSEDPQKENIRCLSTLGHFGFECLPTQLVNKSIQKGFSFNILCVGETGIGKTTLINTLFNTNLKETKSSHFYSKVGLTVKTYELLERNIPLRLTVVKTVGYGDQINKEASYQPVVDYLDAQFEAYLQEELKIKRSLADYHDSRIHVCLYFITPTGHSLKSLDLLTMKSIDRRVNIIPLIAKADSLSKNDLQRFKNNIMSELNSNGIQIYQFQVDDEASAQVNSSGLLPFAVVGSMEEVKVGKRMVRGRHYPWGVLQEVENENHCDFVKLRDLLLSTNMEDLKDQTHTQHYECYRSNRLQKLGFSDTGPDNRPVSFQEMYEAKRREFHNQCQKEEEELKQTFMQRVKEKELTFKDAEKELQDKFEHLKRIQQEEILKLEEERRKLEEQIIDFYKMKAASESAQAQVCTNIKKDKDRKK
uniprot
proteins
function
FUNCTION: Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (PubMed:20181826). Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments (By similarity). {ECO:0000250|UniProtKB:Q6ZU15, ECO:0000269|PubMed:20181826, ECO:0000305}.
uniprot
proteins
mass_dalton
49811
uniprot
proteins
protein_family
Septin GTPase family
uniprot
proteins
protein_family
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20181826
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
33228246
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20181826}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:33228246}. Cell projection, axon {ECO:0000269|PubMed:20181826}. Cell projection, dendrite {ECO:0000269|PubMed:20181826}. Perikaryon {ECO:0000269|PubMed:20181826}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:33228246}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q6ZU15}. Note=Colocalizes with actin stress fibers (By similarity). Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (PubMed:33228246). {ECO:0000250|UniProtKB:Q6ZU15, ECO:0000269|PubMed:33228246}.
uniprot
proteins