Tkt
entrez
21881
canonical
uniprot
P40142
canonical
ensembl
ENSMUSG00000021957
resolver
ensp
ENSMUSP00000022529
resolver
enst
ENSMUST00000022529
resolver
genesymbol
Tkt
resolver
uniprot
Q3U7Y1
resolver
uniprot
Q3UK62
resolver
uniprot
Q545A1
resolver
uniprot
Q9ESA0
resolver
uniprot_entry
TKT_MOUSE
resolver
uniprot_sec
Q3U7Y1
resolver
uniprot_sec
Q3UK62
resolver
uniprot_sec
Q545A1
resolver
uniprot_sec
Q9ESA0
resolver
amino_acid_sequence
MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDIYQKRCEAFGWHTIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQSKKKILATPPQEDAPSVDIANIRMPTPPSYKVGDKIATRKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG
uniprot
proteins
ec_number
2.2.1.1
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity). Thus, catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate (By similarity). The phosphate group of the substrate plays a role in stabilizing the substrate-thiamine intermediate while preventing the formation of the reactive enamine intermediate (By similarity). Can also use fructose-6-phosphate as a ketose donor (By similarity). {ECO:0000250|UniProtKB:P29401}.
uniprot
proteins
mass_dalton
67630
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; pentose phosphate pathway. {ECO:0000305}.
uniprot
proteins
protein_family
Transketolase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
8617775
uniprot
proteins
pubmed
9521875
uniprot
proteins
sequence_length
623
uniprot
proteins