Pou2f3
entrez
116544
canonical
uniprot
P42571
canonical
ensembl
ENSRNOG00000009118
resolver
ensembl
ENSRNOG00055019514
resolver
ensembl
ENSRNOG00060021548
resolver
ensembl
ENSRNOG00065025576
resolver
ensp
ENSRNOP00000084235
resolver
genesymbol
Pou2f3
resolver
genesymbol_syn
Otf11
resolver
genesymbol_syn
Skn-1
resolver
genesymbol_syn
Skn1
resolver
uniprot
A0A8I6A0U7
resolver
uniprot
P42572
resolver
uniprot_entry
PO2F3_RAT
resolver
uniprot_sec
A0A8I6A0U7
resolver
uniprot_sec
P42572
resolver
amino_acid_sequence
MVNLEPMHTEIKMSGDVADSTDARSTFGQVESGNDRNGLDFNRQIKTEDLGDTLQQSLSHRPCHLSQGPTMMPGNQMSGDMASLHPLQQLVLVPGHLQSVSQFLLSQTPPGQQGLQPNLLSFPQQQSTLLLPQTGPGLTSQAVGRPGLSGSSLEPHLEASQHLPGPKHLPGPGGNDEPTDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSASTPSSYPTLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPVKPPIYNSRLVSPSGSLGSLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAMNPSSAAFNSSGSWYRWNHPAYLH
uniprot
proteins
function
FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation (PubMed:7682011). The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues (By similarity). {ECO:0000250|UniProtKB:Q9UKI9, ECO:0000269|PubMed:7682011}.; FUNCTION: [Isoform 2]: Inhibits transactivation by POU2F1. {ECO:0000269|PubMed:7682011}.
uniprot
proteins
mass_dalton
46805
uniprot
proteins
protein_family
Class-2 subfamily
uniprot
proteins
protein_family
POU transcription factor family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
7682011
uniprot
proteins
pubmed
8248794
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P31362}.
uniprot
proteins