Odad2
entrez
74934
canonical
uniprot
B2RY50
canonical
ensembl
ENSMUSG00000061802
resolver
ensp
ENSMUSP00000080028
resolver
ensp
ENSMUSP00000157197
resolver
ensp
ENSMUSP00000272892
resolver
enst
ENSMUST00000081275
resolver
enst
ENSMUST00000234788
resolver
genesymbol
Odad2
resolver
genesymbol_syn
Armc4
resolver
uniprot
Q9CUL6
resolver
uniprot_entry
ODAD2_MOUSE
resolver
uniprot_sec
Q9CUL6
resolver
amino_acid_sequence
MGVALTRLAQWTAAGYETGTLEITPLNESILNEITKFVESFSYKYPQEAKFVFVEPLEWKTYLEPSAFELGYVVSATTAESEETGKDGQPLLFLSVPYIKVRSFGQLSQLLSIATDSKLQEAQACIEANRDPVVKILGPDYNEMKEDPTRLTLLDTIIKDKETYMKRKVAILLKQLDLHLLNHSLKYISLEISLNPGTFKKDIELLKRFSGKGEQTVLESIEYTSDYEFSNGCRAPPWRQIQGEICYVLVKPHDMETLCLTCSTEGVFLNGGKTEEEGEINYERKGEIYKDLVTCLKDKSPVFSENMSKHEIRFTEEQQKDNQIFEKPKTEDGHSSVAGSEKSKIEKISFGKSPMTKRLEPSLNWRVTVDYKDHKSSIKDSQEEKQGKLEKSSSVSVAPSRAQSHRKGGEKVEETVSESSSESEEDEEPPDHRQEANADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFNLAQETCQLAIRDVGGLEVLINLLDTDEVKCKIGSLKILKEISHNPQIRRNIVDLGGLPIMVNILDSPHKSLKCLSAETIANVAKFKRARRAVRQHGGITKLVALLDCGQNSTEPTQPSLYETRDVEVARCGALALWSCSKSHSNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDEETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVIKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQEYENRVLVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMAIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIENAKDAGEMVRSFVGGLELVVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNDKLRRHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATEKARYN
uniprot
proteins
function
FUNCTION: Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule (By similarity). Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (PubMed:23849778). {ECO:0000250|UniProtKB:E1B8W3, ECO:0000269|PubMed:23849778}.
uniprot
proteins
mass_dalton
115266
uniprot
proteins
mutagenesis
MUTAGEN 993; /note="M->K: In Aotea; randomization of laterality. Mutants exhibit a range of cardiovascular anomalies, including right aortic arch, perimembranous and muscular ventricular septal defects, ventricular non-compaction and anomalous venous return. Respiratory cilia are either immotile or have slow dyskinetic motion compared to wild-type animals. Tracheal airway cilia show a marked reduction in outer dynein arms. In the brain, fluid flow is generated by ependymal cilia, but is slower than in wild-type animals. Aotea mutants develop hydrocephalus at 3 to 4 weeks of age and die."; /evidence="ECO:0000269|PubMed:23849778
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23849778
uniprot
proteins
pubmed
24055424
uniprot
proteins
pubmed
34792097
uniprot
proteins
sequence_length
1037
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q5T2S8}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q5T2S8}.
uniprot
proteins