PTPRG
entrez
5793
canonical
uniprot
P23470
canonical
ensembl
ENSG00000144724
resolver
ensp
ENSP00000295874
resolver
ensp
ENSP00000418112
resolver
genesymbol
PTPRG
resolver
genesymbol_syn
PTPG
resolver
hgnc
HGNC:9671
resolver
uniprot
B2RU12
resolver
uniprot
B7ZLX5
resolver
uniprot
Q15623
resolver
uniprot
Q49A02
resolver
uniprot
Q59EE0
resolver
uniprot
Q68DU5
resolver
uniprot_entry
PTPRG_HUMAN
resolver
uniprot_entry
Q49A02_HUMAN
resolver
uniprot_sec
B2RU12
resolver
uniprot_sec
B7ZLX5
resolver
uniprot_sec
Q15623
resolver
uniprot_sec
Q59EE0
resolver
uniprot_sec
Q68DU5
resolver
amino_acid_sequence
MRRLLEPCWWILFLKITSSVLHYVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVVSKSAVRDSWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGIPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFGGGGISSFPSTVWPTRLPTAASASKQAARPVLATTEALASPGPDGDSSPTKDGEGTEEGEKDEKSESEDGEREHEEDGEKDSEKKEKSGVTHAAEERNQTEPSPTPSSPNRTAEGGHQTIPGHEQDHTAVPTDQTGGRRDAGPGLDPDMVTSTQVPPTATEEQYAGSDPKRPEMPSKKPMSRGDRFSEDSRFITVNPAEKNTSGMISRPAPGRMEWIIPLIVVSALTFVCLILLIAVLVYWRGCNKIKSKGFPRRFREVPSSGERGEKGSRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFVKHIGELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYVNSILIPGVGGKTRLEKQFKLVTQCNAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKAMLSLVSTKENGNGPMTVDKNGAVLIADESDPAESMESLV
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Possesses tyrosine phosphatase activity. {ECO:0000269|PubMed:19167335}.
uniprot
proteins
mass_dalton
162003
uniprot
proteins
mutagenesis
MUTAGEN 958; /note="R->E: Loss of dimerization; when associated with E-960."; /evidence="ECO:0000269|PubMed:19167335"; MUTAGEN 960; /note="K->E: Loss of dimerization; when associated with E-958."; /evidence="ECO:0000269|PubMed:19167335"; MUTAGEN 1305; /note="D->K: Loss of dimerization; when associated with K-1306."; /evidence="ECO:0000269|PubMed:19167335"; MUTAGEN 1306; /note="D->K: Loss of dimerization; when associated with K-1305."; /evidence="ECO:0000269|PubMed:19167335
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
protein_family
Receptor class 5 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19167335
uniprot
proteins
pubmed
20133774
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
2169617
uniprot
proteins
pubmed
2170109
uniprot
proteins
pubmed
8382771
uniprot
proteins
pubmed
8833149
uniprot
proteins
sequence_length
1445
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 737..762; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins