Rpain
entrez
69723
canonical
uniprot
Q9CWY9
canonical
ensembl
ENSMUSG00000018449
resolver
ensp
ENSMUSP00000018593
resolver
ensp
ENSMUSP00000127315
resolver
ensp
ENSMUSP00000128903
resolver
ensp
ENSMUSP00000136592
resolver
enst
ENSMUST00000018593
resolver
enst
ENSMUST00000167509
resolver
enst
ENSMUST00000169965
resolver
enst
ENSMUST00000178822
resolver
genesymbol
Rpain
resolver
genesymbol_syn
Rip
resolver
uniprot
F6U9A8
resolver
uniprot
F7B2H8
resolver
uniprot
J3QN46
resolver
uniprot
Q0PL79
resolver
uniprot
Q0PL81
resolver
uniprot
Q0PL82
resolver
uniprot_entry
F6U9A8_MOUSE
resolver
uniprot_entry
F7B2H8_MOUSE
resolver
uniprot_entry
J3QN46_MOUSE
resolver
uniprot_entry
Q0PL79_MOUSE
resolver
uniprot_entry
Q0PL81_MOUSE
resolver
uniprot_entry
Q0PL82_MOUSE
resolver
uniprot_entry
RIP_MOUSE
resolver
amino_acid_sequence
MAESSGSPHRLLYKQVGSPHWKETFRQGCLERMRNSRHRLLNKYRQAAGSTPGTASDRLLVQEVMEEEWASLQSVENCPEALLQLELPLDLAVLQDIEQELCNEEKSIISEYEEDLEFDESCLRRMLAEWEANSLICPVCIKYNLRIMNSVVTCPCGLHIPVHSTDLTEQKLRACLEENVNEHSVHCPHTPVFSVTGGTEEKPSLLMNCLTCDTWAVIL
uniprot
proteins
function
FUNCTION: Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Sumoylation mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
24897
uniprot
proteins
post_translational_modification
PTM: Sumoylated; required for localization in the nuclear PML body and transport of RPA complex in PML body. Upon UV irradiation and during S phase, it is desumoylated, releasing RPA complex that is translocated to sites of DNA damage. Sumoylation takes place at different Lys residues (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
219
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins