Gadd45gip1
entrez
288916
canonical
uniprot
Q5XJW2
canonical
ensembl
ENSRNOG00000003011
resolver
ensembl
ENSRNOG00055007751
resolver
ensembl
ENSRNOG00060012653
resolver
ensembl
ENSRNOG00065010378
resolver
ensp
ENSRNOP00000004027
resolver
ensp
ENSRNOP00055010356
resolver
ensp
ENSRNOP00060016990
resolver
ensp
ENSRNOP00065012824
resolver
enst
ENSRNOT00000004027
resolver
enst
ENSRNOT00055012972
resolver
enst
ENSRNOT00060021493
resolver
enst
ENSRNOT00065016782
resolver
genesymbol
Gadd45gip1
resolver
genesymbol_syn
Mrpl59
resolver
uniprot_entry
G45IP_RAT
resolver
amino_acid_sequence
MAAPATRSRYLLRLTVTLGPRSRSYHAPPPPRRRPAPHWPDRENLMTPRWQLTPRYAAKQFGRHGAISGVPPASLWPSSEQLCELEAEEREWYPSLATMQESLRVQQQAAEARRQAREQHIAECMAKMPQMIENWRKQKRERWEKIQADKERRARLQAEAQEQLGYHVDPRSARFQELLQDLDKQQRKRLKEERQRQKKEARIAAMASAEGQDSAEAQDSAASGKPSS
uniprot
proteins
function
FUNCTION: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but also occur in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. {ECO:0000250|UniProtKB:Q8TAE8}.
uniprot
proteins
mass_dalton
26467
uniprot
proteins
protein_family
Mitochondrion-specific ribosomal protein mL64 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
228
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q8TAE8}. Nucleus {ECO:0000250|UniProtKB:Q8TAE8}. Note=Using N-terminally tagged constructs, has been found in the nucleus. C-terminally tagged constructs are targeted exclusively to mitochondria. This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag. {ECO:0000250|UniProtKB:Q8TAE8}.
uniprot
proteins