TIMM21
entrez
29090
canonical
uniprot
Q9BVV7
canonical
ensembl
ENSG00000075336
resolver
ensp
ENSP00000169551
resolver
enst
ENST00000169551
resolver
genesymbol
C18orf55
resolver
genesymbol
TIMM21
resolver
genesymbol_syn
C18orf55
resolver
genesymbol_syn
TIM21
resolver
hgnc
HGNC:25010
resolver
uniprot
A8K1K8
resolver
uniprot
Q9P010
resolver
uniprot_entry
A8K1K8_HUMAN
resolver
uniprot_entry
TIM21_HUMAN
resolver
uniprot_sec
Q9P010
resolver
amino_acid_sequence
MICTFLRAVQYTEKLHRSSAKRLLLPYIVLNKACLKTEPSLRCGLQYQKKTLRPRCILGVTQKTIWTQGPSPRKAKEDGSKQVSVHRSQRGGTAVPTSQKVKEAGRDFTYLIVVLFGISITGGLFYTIFKELFSSSSPSKIYGRALEKCRSHPEVIGVFGESVKGYGEVTRRGRRQHVRFTEYVKDGLKHTCVKFYIEGSEPGKQGTVYAQVKENPGSGEYDFRYIFVEIESYPRRTIIIEDNRSQDD
uniprot
proteins
function
FUNCTION: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. {ECO:0000269|PubMed:23260140}.
uniprot
proteins
mass_dalton
28202
uniprot
proteins
protein_family
TIM21 family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23260140
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26321642
uniprot
proteins
sequence_length
248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 108..128; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins