NCOA5
entrez
57727
canonical
uniprot
Q9HCD5
canonical
ensembl
ENSG00000124160
resolver
ensp
ENSP00000290231
resolver
ensp
ENSP00000521141
resolver
ensp
ENSP00000540836
resolver
ensp
ENSP00000604653
resolver
ensp
ENSP00000604654
resolver
ensp
ENSP00000638289
resolver
enst
ENST00000290231
resolver
enst
ENST00000870777
resolver
enst
ENST00000934594
resolver
enst
ENST00000934595
resolver
enst
ENST00000968230
resolver
genesymbol
NCOA5
resolver
genesymbol_syn
KIAA1637
resolver
hgnc
HGNC:15909
resolver
uniprot
B2RTV9
resolver
uniprot
E1P5R0
resolver
uniprot
Q6HA99
resolver
uniprot
Q9H1F2
resolver
uniprot
Q9H2T2
resolver
uniprot
Q9H4Y9
resolver
uniprot_entry
NCOA5_HUMAN
resolver
uniprot_sec
B2RTV9
resolver
uniprot_sec
E1P5R0
resolver
uniprot_sec
Q6HA99
resolver
uniprot_sec
Q9H1F2
resolver
uniprot_sec
Q9H2T2
resolver
uniprot_sec
Q9H4Y9
resolver
amino_acid_sequence
MNTAPSRPSPTRRDPYGFGDSRDSRRDRSPIRGSPRREPRDGRNGRDARDSRDIRDPRDLRDHRHSRDLRDHRDSRSVRDVRDVRDLRDFRDLRDSRDFRDQRDPMYDRYRDMRDSRDPMYRREGSYDRYLRMDDYCRRKDDSYFDRYRDSFDGRGPPGPESQSRAKERLKREERRREELYRQYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNECREKEREEIARQAAKMADEAILQERERGGPEEGVRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRERKERLMRSSTDSLPGPISRQPLGATSGASLKTQPSSQPLQSGQVLPSATPTPSAPPTSQQELQAKILSLFNSGTVTANSSSASPSVAAGNTPNQNFSTAANSQPQQRSQASGNQPPSILGQGGSAQNMGPRPGAPSQGLFGQPSSRLAPASNMTSQRPVSSTGINFDNPSVQKALDTLIQSGPALSHLVSQTTAQMGQPQAPMGSYQRHY
uniprot
proteins
function
FUNCTION: Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). {ECO:0000269|PubMed:15073177}.
uniprot
proteins
mass_dalton
65536
uniprot
proteins
mutagenesis
MUTAGEN 342; /note="I->A: Abolishes E2-inducible strong interaction with ESR1, but not basal interaction."; /evidence="ECO:0000269|PubMed:11113208"; MUTAGEN 348..349; /note="LL->AA: Abolishes interaction with ESR1."; /evidence="ECO:0000269|PubMed:11113208
uniprot
proteins
pubmed
10997877
uniprot
proteins
pubmed
11113208
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12168954
uniprot
proteins
pubmed
15073177
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17890166
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
579
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins