Asrgl1
entrez
246307
canonical
uniprot
Q8VI04
canonical
ensembl
ENSRNOG00000020202
resolver
ensembl
ENSRNOG00055017847
resolver
ensembl
ENSRNOG00060033187
resolver
ensembl
ENSRNOG00065033931
resolver
ensp
ENSRNOP00000027459
resolver
ensp
ENSRNOP00055024269
resolver
ensp
ENSRNOP00060047502
resolver
ensp
ENSRNOP00065047942
resolver
enst
ENSRNOT00000027459
resolver
enst
ENSRNOT00055030197
resolver
enst
ENSRNOT00060057540
resolver
enst
ENSRNOT00065058265
resolver
genesymbol
Asrgl1
resolver
genesymbol_syn
Alp
resolver
genesymbol_syn
Gliap
resolver
genesymbol_syn
Hiob
resolver
uniprot
Q8CG44
resolver
uniprot_entry
ASGL1_RAT
resolver
uniprot_sec
Q8CG44
resolver
amino_acid_sequence
MATARPSSCGRDSVPATPRASIDVSLVVVVHGGGASNISPGRKELVSEGIAKAATEGYNILKAGGSAVDAVEGAVTMLENDPEFNAGYGSVLNADGDIEMDASIMDGKDLSAGAVSAVRCIANPVKLARLVMEKTPHCFLTGRGAEKFAADMGIPQTPAEKLITERTKKHLEKEKLEKGAQKADCPKNSGTVGAVALDCKGNLAYATSTGGIVNKMVGRVGDSPCIGAGGYADNNLGAVSTTGHGESILKVNLARLALFHVEQGKTVDEAATLALDYMKSKLKGLGGLILINKTGDWVAKWTSASMPWAAVKNGKLQAGIDLCETKTRNLPTC
uniprot
proteins
ec_number
3.4.19.5
uniprot
proteins
ec_number
3.5.1.1
uniprot
proteins
function
FUNCTION: Has both L-asparaginase and beta-aspartyl peptidase activity. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine (By similarity). May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. {ECO:0000250|UniProtKB:Q7L266, ECO:0000269|PubMed:12753071}.
uniprot
proteins
mass_dalton
34410
uniprot
proteins
post_translational_modification
PTM: Cleaved into an alpha and beta chain by autocatalysis; this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity. {ECO:0000250|UniProtKB:Q7L266}.
uniprot
proteins
protein_family
Ntn-hydrolase family
uniprot
proteins
pubmed
11984834
uniprot
proteins
pubmed
12753071
uniprot
proteins
sequence_length
333
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11984834, ECO:0000269|PubMed:12753071}. Note=Midpiece of sperm tail.
uniprot
proteins