LVRN
entrez
206338
canonical
uniprot
Q6Q4G3
canonical
ensembl
ENSG00000172901
resolver
ensp
ENSP00000350541
resolver
genesymbol
LVRN
resolver
genesymbol_syn
AQPEP
resolver
hgnc
HGNC:26904
resolver
uniprot
A8K6J0
resolver
uniprot
C9JGD2
resolver
uniprot
Q32MR1
resolver
uniprot
Q4G0I9
resolver
uniprot
Q4G0V2
resolver
uniprot
Q86XA3
resolver
uniprot
Q8NBZ2
resolver
uniprot_entry
AMPQ_HUMAN
resolver
uniprot_sec
A8K6J0
resolver
uniprot_sec
C9JGD2
resolver
uniprot_sec
Q32MR1
resolver
uniprot_sec
Q4G0I9
resolver
uniprot_sec
Q4G0V2
resolver
uniprot_sec
Q86XA3
resolver
uniprot_sec
Q8NBZ2
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by bestatin. {ECO:0000269|PubMed:17525158}.
uniprot
proteins
amino_acid_sequence
MGPPSSSGFYVSRAVALLLAGLVAALLLALAVLAALYGHCERVPPSELPGLRDLEAESSPPLRQKPTPTPKPSSARELAVTTTPSNWRPPGPWDQLRLPPWLVPLHYDLELWPQLRPDELPAGSLPFTGRVNITVRCTVATSRLLLHSLFQDCERAEVRGPLSPGTGNATVGRVPVDDVWFALDTEYMVLELSEPLKPGSSYELQLSFSGLVKEDLREGLFLNVYTDQGERRALLASQLEPTFARYVFPCFDEPALKATFNITMIHHPSYVALSNMPKLGQSEKEDVNGSKWTVTTFSTTPHMPTYLVAFVICDYDHVNRTERGKEIRIWARKDAIANGSADFALNITGPIFSFLEDLFNISYSLPKTDIIALPSFDNHAMENWGLMIFDESGLLLEPKDQLTEKKTLISYVVSHEIGHQWFGNLVTMNWWNNIWLNEGFASYFEFEVINYFNPKLPRNEIFFSNILHNILREDHALVTRAVAMKVENFKTSEIQELFDIFTYSKGASMARMLSCFLNEHLFVSALKSYLKTFSYSNAEQDDLWRHFQMAIDDQSTVILPATIKNIMDSWTHQSGFPVITLNVSTGVMKQEPFYLENIKNRTLLTSNDTWIVPILWIKNGTTQPLVWLDQSSKVFPEMQVSDSDHDWVILNLNMTGYYRVNYDKLGWKKLNQQLEKDPKAIPVIHRLQLIDDAFSLSKNNYIEIETALELTKYLAEEDEIIVWHTVLVNLVTRDLVSEVNIYDIYSLLKRYLLKRLNLIWNIYSTIIRENVLALQDDYLALISLEKLFVTACWLGLEDCLQLSKELFAKWVDHPENEIPYPIKDVVLCYGIALGSDKEWDILLNTYTNTTNKEEKIQLAYAMSCSKDPWILNRYMEYAISTSPFTSNETNIIEVVASSEVGRYVAKDFLVNNWQAVSKRYGTQSLINLIYTIGRTVTTDLQIVELQQFFSNMLEEHQRIRVHANLQTIKNENLKNKKLSARIAAWLRRNT
uniprot
proteins
ec_number
3.4.11.-
uniprot
proteins
function
FUNCTION: Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C. {ECO:0000269|PubMed:17525158}.
uniprot
proteins
mass_dalton
113283
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:17525158}.
uniprot
proteins
protein_family
Peptidase M1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14706636
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17525158
uniprot
proteins
sequence_length
990
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000303|PubMed:17525158}; Single-pass type II membrane protein {ECO:0000303|PubMed:17525158}.
uniprot
proteins
transmembrane_region
TRANSMEM 14..34; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins