Ifi27l2a
entrez
76933
canonical
uniprot
Q8R412
canonical
ensembl
ENSMUSG00000079017
resolver
ensp
ENSMUSP00000054698
resolver
ensp
ENSMUSP00000329969
resolver
ensp
ENSMUSP00000359068
resolver
enst
ENSMUST00000055071
resolver
genesymbol
Ifi27l2a
resolver
genesymbol_syn
Ifi27
resolver
genesymbol_syn
Isg12
resolver
uniprot_entry
IF27A_MOUSE
resolver
amino_acid_sequence
MLGTLFGSAIGGALAVAGAPVALAAMGFTGTGIAAASIAAKMMSAAAIANGGGVAAGSLVATLQSAGVLGLSTSTNAILGAAGAAVGALL
uniprot
proteins
function
FUNCTION: May be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors (PubMed:22427340). Through the regulation of NR4A1 transcriptional activity, may play a role in the vascular response to injury (PubMed:22427340). {ECO:0000269|PubMed:22427340}.
uniprot
proteins
mass_dalton
7929
uniprot
proteins
protein_family
IFI6/IFI27 family
uniprot
proteins
pubmed
12388728
uniprot
proteins
pubmed
14728724
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22427340
uniprot
proteins
sequence_length
90
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus inner membrane {ECO:0000305|PubMed:22427340}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 28..48; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 67..89; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins