Morf4l2
entrez
56397
canonical
uniprot
Q9R0Q4
canonical
ensembl
ENSMUSG00000031422
resolver
ensp
ENSMUSP00000033797
resolver
ensp
ENSMUSP00000108720
resolver
ensp
ENSMUSP00000108722
resolver
ensp
ENSMUSP00000126363
resolver
ensp
ENSMUSP00000129774
resolver
ensp
ENSMUSP00000131909
resolver
ensp
ENSMUSP00000132643
resolver
ensp
ENSMUSP00000218398
resolver
enst
ENSMUST00000033797
resolver
enst
ENSMUST00000080411
resolver
enst
ENSMUST00000113097
resolver
enst
ENSMUST00000164609
resolver
enst
ENSMUST00000166478
resolver
enst
ENSMUST00000166930
resolver
enst
ENSMUST00000169418
resolver
genesymbol
Morf4l2
resolver
genesymbol_syn
Kiaa0026
resolver
genesymbol_syn
Sid393
resolver
uniprot
A2AEB2
resolver
uniprot
Q3UL62
resolver
uniprot
Q6DIB1
resolver
uniprot
Q6ZQK7
resolver
uniprot
Q8C201
resolver
uniprot
Q8C6C2
resolver
uniprot_entry
MO4L2_MOUSE
resolver
uniprot_sec
A2AEB2
resolver
uniprot_sec
Q3UL62
resolver
uniprot_sec
Q6DIB1
resolver
uniprot_sec
Q6ZQK7
resolver
uniprot_sec
Q8C201
resolver
uniprot_sec
Q8C6C2
resolver
amino_acid_sequence
MSSRKQASQTRGQQSAEEDNFKKPTRSNMQRSKMRGAASGKKSAGSQPKNLDPALPGRWGGRSAENPPSGSVRKTRKNKQKAPGNGDGGSTSEVPQPPRKKRARADPTVESEEAFKSRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKSQGNVDNKEYAVNEVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAPMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL
uniprot
proteins
function
FUNCTION: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
32184
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
288
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00972}.
uniprot
proteins