Osgep
entrez
66246
canonical
uniprot
Q8BWU5
canonical
ensembl
ENSMUSG00000006289
resolver
ensp
ENSMUSP00000124039
resolver
ensp
ENSMUSP00000125155
resolver
enst
ENSMUST00000159292
resolver
enst
ENSMUST00000160393
resolver
genesymbol
Osgep
resolver
uniprot
A0A0R4J1Y3
resolver
uniprot
Q3UQ67
resolver
uniprot
Q99LN8
resolver
uniprot_entry
A0A0R4J1Y3_MOUSE
resolver
uniprot_entry
OSGEP_MOUSE
resolver
uniprot_entry
Q3UQ67_MOUSE
resolver
uniprot_sec
Q99LN8
resolver
amino_acid_sequence
MPAVLGFEGSANKIGVGVVRDGTVLANPRRTYVTAPGTGFLPGDTARHHRAVILDLLQEALAEAGLTSKDIDCIAFTKGPGMGAPLASVAVVARTVAQLWNKPLLGVNHCIGHIEMGRLITGAVNPTVLYVSGGNTQVISYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRGKKLVELPYTVKGMDVSFSGILSFIEDAAQRMLATGECTPEDLCFSLQETVFAMLVEITERAMAHCGSKEALIVGGVGCNLRLQEMMGTMCQERGAQLFATDERFCVDNGAMIAQAGWEMFQAGHRTPLKDSAITQRYRTDEVEVTWRD
uniprot
proteins
ec_number
2.3.1.234
uniprot
proteins
function
FUNCTION: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. {ECO:0000255|HAMAP-Rule:MF_03180}.
uniprot
proteins
mass_dalton
36301
uniprot
proteins
protein_family
KAE1 / TsaD family
uniprot
proteins
pubmed
12200116
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28805828
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03180}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03180}.
uniprot
proteins