NPAS1
entrez
4861
canonical
uniprot
Q99742
canonical
ensembl
ENSG00000130751
resolver
ensp
ENSP00000398689
resolver
ensp
ENSP00000469142
resolver
ensp
ENSP00000472679
resolver
ensp
ENSP00000576500
resolver
ensp
ENSP00000689945
resolver
ensp
ENSP00000758362
resolver
ensp
ENSP00000797655
resolver
genesymbol
NPAS1
resolver
genesymbol_syn
BHLHE11
resolver
genesymbol_syn
MOP5
resolver
genesymbol_syn
PASD5
resolver
hgnc
HGNC:7894
resolver
uniprot
B4DR69
resolver
uniprot
Q99632
resolver
uniprot
Q9BY83
resolver
uniprot_entry
NPAS1_HUMAN
resolver
uniprot_sec
B4DR69
resolver
uniprot_sec
Q99632
resolver
uniprot_sec
Q9BY83
resolver
amino_acid_sequence
MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRKEKSRNAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPPWGLRAAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPGPPTPPSVSSSSSSSSSLADTPEIEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVIHVTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKSPGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAAPAENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPVRPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPGTIRYGPAELGLVYPHLQRLGPGPALPEAFYPPLGLPYPGPAGTRLPRKGD
uniprot
proteins
function
FUNCTION: May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level (By similarity). Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:P97459}.
uniprot
proteins
mass_dalton
62702
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9012850
uniprot
proteins
pubmed
9079689
uniprot
proteins
sequence_length
590
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
uniprot
proteins