SLC39A12
entrez
221074
canonical
uniprot
Q504Y0
canonical
ensembl
ENSG00000148482
resolver
ensp
ENSP00000366586
resolver
ensp
ENSP00000366588
resolver
ensp
ENSP00000366591
resolver
ensp
ENSP00000440445
resolver
genesymbol
SLC39A12
resolver
genesymbol_syn
ZIP12
resolver
hgnc
HGNC:20860
resolver
uniprot
B7Z2Y9
resolver
uniprot
B7ZL35
resolver
uniprot
C9JJL4
resolver
uniprot
F5GX72
resolver
uniprot
Q49AN8
resolver
uniprot
Q4G0L3
resolver
uniprot
Q5VWV8
resolver
uniprot
Q5VWV9
resolver
uniprot
Q6NZY5
resolver
uniprot
Q96NN4
resolver
uniprot_entry
S39AC_HUMAN
resolver
uniprot_sec
B7Z2Y9
resolver
uniprot_sec
B7ZL35
resolver
uniprot_sec
C9JJL4
resolver
uniprot_sec
F5GX72
resolver
uniprot_sec
Q49AN8
resolver
uniprot_sec
Q4G0L3
resolver
uniprot_sec
Q5VWV8
resolver
uniprot_sec
Q5VWV9
resolver
uniprot_sec
Q6NZY5
resolver
uniprot_sec
Q96NN4
resolver
amino_acid_sequence
MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNHSRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI
uniprot
proteins
function
FUNCTION: Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane. The transport activity is temperature dependent. May play a role in neurulation and neurite extension. May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis. {ECO:0000250|UniProtKB:Q5FWH7}.
uniprot
proteins
mass_dalton
76666
uniprot
proteins
protein_family
ZIP transporter (TC 2.A.5) family
uniprot
proteins
pubmed
12107410
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15342556
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16311021
uniprot
proteins
pubmed
16959974
uniprot
proteins
sequence_length
691
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q5FWH7}; Multi-pass membrane protein {ECO:0000255}. Note=At low Zn(2+) extracellular concentration, is redistributed from the perinuclear space to the cytoplasm and plasma membrane. {ECO:0000250|UniProtKB:Q5FWH7}.
uniprot
proteins
transmembrane_region
TRANSMEM 203..223; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 370..390; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 399..419; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 449..469; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 539..559; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 603..623; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 632..652; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 664..684; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins