Asb1
entrez
65247
canonical
uniprot
Q9WV74
canonical
ensembl
ENSMUSG00000026311
resolver
ensp
ENSMUSP00000084054
resolver
ensp
ENSMUSP00000140281
resolver
ensp
ENSMUSP00000140731
resolver
enst
ENSMUST00000086843
resolver
enst
ENSMUST00000188879
resolver
genesymbol
Asb1
resolver
uniprot
G3X9J5
resolver
uniprot
Q3U5A0
resolver
uniprot_entry
ASB1_MOUSE
resolver
uniprot_entry
G3X9J5_MOUSE
resolver
uniprot_entry
Q3U5A0_MOUSE
resolver
amino_acid_sequence
MAEGGTGPDGRAGPGPAGPNLKEWLREQFCDHPLEHCDDTRLHDAAYVGDLQTLRNLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTEILLEAGADPNGSRHHRSTPVYHASRVGRDDILKALIRYGADVDVNHHLTPDTRPPFSRRLTSLVVCPLYISAAYHNLQCFRLLLQAGANPDFNCNGPVNTQEFYRGSPGCVMDAVLRHGCEAAFVSLLVEFGANLNLVKWESLGPEARGRRKMDPEALQVFKEARSIPRTLLSLCRVAVRRALGKYRLHLVPSLPLPDPIKKFLLYE
uniprot
proteins
function
FUNCTION: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Mediates Notch-induced ubiquitination and degradation of TCF3/E2A and JAK2 (By similarity). May play a role in testis development (PubMed:11509662). {ECO:0000250|UniProtKB:Q9Y576, ECO:0000269|PubMed:11509662}.
uniprot
proteins
mass_dalton
37232
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
protein_family
Ankyrin SOCS box (ASB) family
uniprot
proteins
pubmed
11111040
uniprot
proteins
pubmed
11509662
uniprot
proteins
pubmed
33431678
uniprot
proteins
sequence_length
336
uniprot
proteins