DLX1
entrez
1745
canonical
uniprot
P56177
canonical
ensembl
ENSG00000144355
resolver
ensembl
ENSG00000292098
resolver
ensp
ENSP00000341786
resolver
ensp
ENSP00000354478
resolver
genesymbol
DLX1
resolver
hgnc
HGNC:2914
resolver
uniprot
D3DPD7
resolver
uniprot
Q53ZU4
resolver
uniprot
Q7Z724
resolver
uniprot
Q8IYB2
resolver
uniprot
X5D2F9
resolver
uniprot_entry
DLX1_HUMAN
resolver
uniprot_entry
X5D2F9_HUMAN
resolver
uniprot_sec
D3DPD7
resolver
uniprot_sec
Q53ZU4
resolver
uniprot_sec
Q7Z724
resolver
uniprot_sec
Q8IYB2
resolver
amino_acid_sequence
MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTSWYPSAHQEAMQQPQLM
uniprot
proteins
function
FUNCTION: Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (By similarity). Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity). {ECO:0000250|UniProtKB:Q64317, ECO:0000269|PubMed:14671321}.
uniprot
proteins
mass_dalton
27320
uniprot
proteins
protein_family
Distal-less homeobox family
uniprot
proteins
pubmed
14671321
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
7907794
uniprot
proteins
sequence_length
255
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14671321}.
uniprot
proteins