Cotl1
entrez
72042
canonical
uniprot
Q9CQI6
canonical
ensembl
ENSMUSG00000031827
resolver
ensp
ENSMUSP00000034285
resolver
enst
ENSMUST00000034285
resolver
genesymbol
Cotl1
resolver
genesymbol_syn
Clp
resolver
uniprot
Q544F6
resolver
uniprot_entry
COTL1_MOUSE
resolver
uniprot_entry
Q544F6_MOUSE
resolver
amino_acid_sequence
MATKIDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIRSELKKAGGANYDAQSE
uniprot
proteins
function
FUNCTION: Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis (By similarity). {ECO:0000250, ECO:0000269|PubMed:11785969}.
uniprot
proteins
mass_dalton
15944
uniprot
proteins
protein_family
Actin-binding proteins ADF family
uniprot
proteins
protein_family
Coactosin subfamily
uniprot
proteins
pubmed
11785969
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
142
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q14019}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q14019}. Nucleus {ECO:0000250|UniProtKB:Q14019}.
uniprot
proteins