Rbm47
entrez
305340
canonical
uniprot
Q66H68
canonical
ensembl
ENSRNOG00000002408
resolver
ensembl
ENSRNOG00055017912
resolver
ensembl
ENSRNOG00060015515
resolver
ensembl
ENSRNOG00065013986
resolver
ensp
ENSRNOP00000003327
resolver
ensp
ENSRNOP00055024403
resolver
ensp
ENSRNOP00060021242
resolver
ensp
ENSRNOP00065017988
resolver
enst
ENSRNOT00000003327
resolver
enst
ENSRNOT00055030343
resolver
enst
ENSRNOT00060026565
resolver
enst
ENSRNOT00065023100
resolver
genesymbol
Rbm47
resolver
uniprot_entry
RBM47_RAT
resolver
amino_acid_sequence
MTAEDSTTAMNSDPTVGSSTKVPEGVAGAPNEAALLALMERTGYNMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFETVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRGEILEEIAKVTEGVLNVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMQTVKILYVRNLMIETTEETIKRSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAAKGGGGSAEAVAQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKTGSIRGRGRGAAGNRTPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEISAVNPVAIKPGTVAIPAIGAQYSMFQAAPAPKIIEDGKIHTMEHMISPIAVQPDPATAAAAAAAAAAAAVIPAVSTPPPFQGRPITPVYTVAPNVPRIPTAGIYGASYVPFAAPATATIATLQKNAAAAVYGGYAGYIPQAFPAALQVPIHDVYQTY
uniprot
proteins
function
FUNCTION: Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing. Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules. Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10. Also involved in the alternative splicing of several genes including TJP1. Binds the pre-mRNA (U)GCAUG consensus sequences in downstream intronic regions of alternative exons regulating their exclusion and inclusion into mRNAs (By similarity). Independently of its RNA-binding activity, could negatively regulate MAVS by promoting its lysosomal degradation (By similarity). {ECO:0000250|UniProtKB:A0A8M1NHK4, ECO:0000250|UniProtKB:A0AV96}.
uniprot
proteins
mass_dalton
64094
uniprot
proteins
protein_family
RRM RBM47 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
590
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:A0AV96}. Cytoplasm {ECO:0000250|UniProtKB:A0AV96}.
uniprot
proteins