Txndc17
entrez
52700
canonical
uniprot
Q9CQM5
canonical
ensembl
ENSMUSG00000020803
resolver
ensp
ENSMUSP00000021158
resolver
enst
ENSMUST00000021158
resolver
genesymbol
Txndc17
resolver
genesymbol_syn
Txnl5
resolver
uniprot
Q3TE14
resolver
uniprot
Q921A9
resolver
uniprot
Q9D0Y4
resolver
uniprot_entry
TXD17_MOUSE
resolver
uniprot_sec
Q3TE14
resolver
uniprot_sec
Q921A9
resolver
uniprot_sec
Q9D0Y4
resolver
amino_acid_sequence
MATFEEVSVLGFEEFDKAVKEHEGKTIFAYFSGSKDTEGKSWCPDCVEAEPVIREGLKHVTEDCVFIYCQVGDKPYWKDPNNDFRQKLKITAVPTLLKYGTPQKLVESECCQSSLVEMIFSED
uniprot
proteins
function
FUNCTION: Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
14015
uniprot
proteins
post_translational_modification
PTM: The oxidized protein is reduced by TRXR1. {ECO:0000250}.
uniprot
proteins
protein_family
Thioredoxin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
123
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins