Jade2
entrez
76901
canonical
uniprot
Q6ZQF7
canonical
ensembl
ENSMUSG00000020387
resolver
ensp
ENSMUSP00000020655
resolver
ensp
ENSMUSP00000273104
resolver
ensp
ENSMUSP00000273106
resolver
ensp
ENSMUSP00000273108
resolver
genesymbol
Jade2
resolver
genesymbol_syn
Kiaa0239
resolver
genesymbol_syn
Phf15
resolver
uniprot
Q3UHD5
resolver
uniprot
Q6IE83
resolver
uniprot_entry
JADE2_MOUSE
resolver
uniprot_sec
Q3UHD5
resolver
uniprot_sec
Q6IE83
resolver
amino_acid_sequence
MEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRLLPPLKGPPTQMSPDSPTLGEGAHPDWPGGSRYDLDEIDAYWLELLNSELKEMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCITAFHVTCAFDRGLEMRTILADNDEVKFKSLCQEHSDGGPRSEPTSEPVEPSQAVEDLEKVTLRKQRLQQLEENFYELVEPAEVAERLDLAEALVDFIYQYWKLKRRANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGKKNDSKRKGREGPKGSSPEKKEKVKAGPESVLGQLGLSTSFPIDGTFFNSWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPSPLQDGPSARTTPDKQPKKAWAQDGKGTQGPPMRKPPRRTSSHLPSSPAAGDCPVPATLESPPPLASEILDKTAPMASDLNVQVPGPTVSPKPLGRLRPPREMKVSRKSPGARSDAGTGLPSAVAERPKVSLHFDTEADGYFSDEEMSDSEVEAEDSGVQRASREAGAEEVVRMGVLAS
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (By similarity). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself (PubMed:25018020). Positive regulator of neurogenesis (PubMed:25018020). {ECO:0000250|UniProtKB:Q9NQC1, ECO:0000269|PubMed:25018020}.
uniprot
proteins
mass_dalton
92174
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000305|PubMed:25018020}.
uniprot
proteins
protein_family
JADE family
uniprot
proteins
pubmed
14612400
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
25018020
uniprot
proteins
sequence_length
829
uniprot
proteins