LTB4R
entrez
1241
canonical
uniprot
Q15722
canonical
ensembl
ENSG00000213903
resolver
ensembl
ENSG00000285456
resolver
ensp
ENSP00000307445
resolver
ensp
ENSP00000380002
resolver
ensp
ENSP00000380008
resolver
ensp
ENSP00000494730
resolver
ensp
ENSP00000495466
resolver
ensp
ENSP00000495785
resolver
ensp
ENSP00000532070
resolver
ensp
ENSP00000532071
resolver
ensp
ENSP00000532072
resolver
ensp
ENSP00000594225
resolver
ensp
ENSP00000594226
resolver
ensp
ENSP00000594227
resolver
ensp
ENSP00000630536
resolver
ensp
ENSP00000630537
resolver
enst
ENST00000345363
resolver
enst
ENST00000396782
resolver
enst
ENST00000396789
resolver
enst
ENST00000646659
resolver
enst
ENST00000646739
resolver
enst
ENST00000647085
resolver
enst
ENST00000862011
resolver
enst
ENST00000862012
resolver
enst
ENST00000862013
resolver
enst
ENST00000924166
resolver
enst
ENST00000924167
resolver
enst
ENST00000924168
resolver
enst
ENST00000960477
resolver
enst
ENST00000960478
resolver
genesymbol
LTB4R
resolver
genesymbol_syn
BLT
resolver
genesymbol_syn
BLT1
resolver
genesymbol_syn
BLTR
resolver
genesymbol_syn
CMKRL1
resolver
genesymbol_syn
GPR16
resolver
genesymbol_syn
P2RY7
resolver
hgnc
HGNC:6713
resolver
uniprot
Q13305
resolver
uniprot
Q53XV5
resolver
uniprot
Q92641
resolver
uniprot
Q9BSU5
resolver
uniprot_entry
LT4R1_HUMAN
resolver
uniprot_sec
Q13305
resolver
uniprot_sec
Q53XV5
resolver
uniprot_sec
Q92641
resolver
uniprot_sec
Q9BSU5
resolver
amino_acid_sequence
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
uniprot
proteins
function
FUNCTION: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
uniprot
proteins
mass_dalton
37557
uniprot
proteins
mutagenesis
MUTAGEN 308; /note="T->P,A: No effect on affinity for leukotriene B4, induces resistance to desensitization by GRK6, but minor effect on phosphorylation by GRK6."; /evidence="ECO:0000269|PubMed:12077128"; MUTAGEN 310; /note="S->A: No effect on affinity for leukotriene B4 or on desensitization by GRK6."; /evidence="ECO:0000269|PubMed:12077128
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization. {ECO:0000269|PubMed:12077128}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10934229
uniprot
proteins
pubmed
12077128
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8558062
uniprot
proteins
pubmed
8702478
uniprot
proteins
pubmed
8921391
uniprot
proteins
pubmed
9177352
uniprot
proteins
sequence_length
352
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 20..42; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 92..113; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 139..159; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 222..242; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 269..289; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins