Slc25a51
entrez
230125
canonical
uniprot
Q5HZI9
canonical
ensembl
ENSMUSG00000045973
resolver
ensp
ENSMUSP00000112044
resolver
ensp
ENSMUSP00000134132
resolver
enst
ENSMUST00000116341
resolver
enst
ENSMUST00000132815
resolver
genesymbol
Slc25a51
resolver
genesymbol_syn
Mcart1
resolver
uniprot
Q3U190
resolver
uniprot
Q3UCW5
resolver
uniprot_entry
S2551_MOUSE
resolver
uniprot_sec
Q3U190
resolver
uniprot_sec
Q3UCW5
resolver
amino_acid_sequence
MMDSEAHEKRPPMLTSSNQDLSPHIAGVGDMKHYLCGYCAAFNNVAITYPVQKILFRQQLYGIKTRDAVLQLRKDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSRLLHKHVSSAPEFATRSVAALLAGTTEAILTPFERVQTLLQDHKHHDKFTNTYQAFRALRCHGIAEYYRGMVPILFRNGFGNVLFFGLRGPIKESLPTATTYSAHLVNDFICGGVLGAVLGFLSFPINVVKARIQSQIGGPFLSLPMVFKTIWIERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKIV
uniprot
proteins
function
FUNCTION: Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria. Mitochondrial NAD(+) is required for glycolysis and mitochondrial respiration. Compared to SLC25A52, SLC25A51-mediated transport is essential for the import of NAD(+) in mitochondria. The transport mechanism, uniport or antiport, its electrogenicity and substrate selectivity, remain to be elucidated. {ECO:0000250|UniProtKB:Q9H1U9}.
uniprot
proteins
mass_dalton
33689
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9H1U9}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..56; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 85..105; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 119..139; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 180..200; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 216..236; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 269..290; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins