NUTF2
entrez
10204
canonical
uniprot
P61970
canonical
ensembl
ENSG00000102898
resolver
ensp
ENSP00000219169
resolver
ensp
ENSP00000456428
resolver
ensp
ENSP00000457022
resolver
ensp
ENSP00000457989
resolver
ensp
ENSP00000515103
resolver
ensp
ENSP00000515104
resolver
ensp
ENSP00000569842
resolver
ensp
ENSP00000569843
resolver
ensp
ENSP00000569844
resolver
ensp
ENSP00000569846
resolver
ensp
ENSP00000609688
resolver
ensp
ENSP00000609689
resolver
ensp
ENSP00000609690
resolver
ensp
ENSP00000609691
resolver
enst
ENST00000219169
resolver
enst
ENST00000568396
resolver
enst
ENST00000569436
resolver
enst
ENST00000700613
resolver
enst
ENST00000700614
resolver
enst
ENST00000899783
resolver
enst
ENST00000899784
resolver
enst
ENST00000899785
resolver
enst
ENST00000899787
resolver
enst
ENST00000939629
resolver
enst
ENST00000939630
resolver
enst
ENST00000939631
resolver
enst
ENST00000939632
resolver
genesymbol
NUTF2
resolver
genesymbol_syn
NTF2
resolver
hgnc
HGNC:13722
resolver
uniprot
B2R4G7
resolver
uniprot
P13662
resolver
uniprot
Q6IB67
resolver
uniprot_entry
NTF2_HUMAN
resolver
uniprot_sec
B2R4G7
resolver
uniprot_sec
P13662
resolver
uniprot_sec
Q6IB67
resolver
amino_acid_sequence
MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG
uniprot
proteins
function
FUNCTION: Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import. {ECO:0000269|PubMed:10679025, ECO:0000269|PubMed:7744965}.
uniprot
proteins
mass_dalton
14478
uniprot
proteins
mutagenesis
MUTAGEN 42; /note="E->K: No effect on localization to the nucleoplasm."; /evidence="ECO:0000269|PubMed:10679025"; MUTAGEN 124; /note="Missing: No effect on localization to the nucleoplasm."; /evidence="ECO:0000269|PubMed:10679025
uniprot
proteins
pubmed
10679025
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18266911
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
3380696
uniprot
proteins
pubmed
7744965
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:10679025, ECO:0000269|PubMed:7744965}. Nucleus outer membrane {ECO:0000250|UniProtKB:P61972}. Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P61972}. Nucleus inner membrane {ECO:0000250|UniProtKB:P61972}. Nucleus, nucleoplasm {ECO:0000269|PubMed:10679025}. Note=At steady state it is essentially nucleoplasmic, enriched in nucleoplasmic foci. {ECO:0000269|PubMed:10679025}.
uniprot
proteins