ODAD2
entrez
55130
canonical
uniprot
Q5T2S8
canonical
ensembl
ENSG00000169126
resolver
ensp
ENSP00000306410
resolver
ensp
ENSP00000499983
resolver
ensp
ENSP00000500120
resolver
ensp
ENSP00000500782
resolver
ensp
ENSP00000522682
resolver
ensp
ENSP00000593142
resolver
ensp
ENSP00000593147
resolver
enst
ENST00000672841
resolver
genesymbol
ODAD2
resolver
genesymbol_syn
ARMC4
resolver
hgnc
HGNC:25583
resolver
uniprot
A0A140VKF7
resolver
uniprot
A0A5F9ZH22
resolver
uniprot
A8K906
resolver
uniprot
B7Z7A1
resolver
uniprot
B7Z7I1
resolver
uniprot
B7Z7Y0
resolver
uniprot
Q9H0C0
resolver
uniprot_entry
A0A140VKF7_HUMAN
resolver
uniprot_entry
A0A5F9ZH22_HUMAN
resolver
uniprot_entry
B7Z7A1_HUMAN
resolver
uniprot_entry
B7Z7Y0_HUMAN
resolver
uniprot_entry
ODAD2_HUMAN
resolver
uniprot_sec
A8K906
resolver
uniprot_sec
B7Z7I1
resolver
uniprot_sec
Q9H0C0
resolver
amino_acid_sequence
MGVALRKLTQWTAAGHGTGILEITPLNEAILKEIIVFVESFIYKHPQEAKFVFVEPLEWNTSLAPSAFESGYVVSETTVKSEEVDKNGQPLLFLSVPQIKIRSFGQLSRLLLIAKTGKLKEAQACVEANRDPIVKILGSDYNTMKENSIALNILGKITRDDDPESEIKMKIAMLLKQLDLHLLNHSLKHISLEISLSPMTVKKDIELLKRFSGKGNQTVLESIEYTSDYEFSNGCRAPPWRQIRGEICYVLVKPHDGETLCITCSAGGVFLNGGKTDDEGDVNYERKGSIYKNLVTFLREKSPKFSENMSKLGISFSEDQQKEKDQLGKAPKKEEAAALRKDISGSDKRSLEKNQINFWRNQMTKRWEPSLNWKTTVNYKGKGSAKEIQEDKHTGKLEKPRPSVSHGRAQLLRKSAEKIEETVSDSSSESEEDEEPPDHRQEASADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEVKCKIGSLKILKEISHNPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVAKFKRARRVVRQHGGITKLVALLDCAHDSTKPAQSSLYEARDVEVARCGALALWSCSKSHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQERENRVIVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMMIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFVGGLELIVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNNKLRHHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATEKARYT
uniprot
proteins
disease_involvement
DISEASE: Ciliary dyskinesia, primary, 23 (CILD23) [MIM:615451]: A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Patients may exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. {ECO:0000269|PubMed:23849778, ECO:0000269|PubMed:25186273}. Note=The disease is caused by variants affecting the gene represented in this entry. Contrary to the wild-type protein, disease-causing variant Trp-927 is unable to rescue the phenotype (randomization of heart looping) of the morpholino knockdown of the orthologous protein in zebrafish (PubMed:23849778). {ECO:0000269|PubMed:23849778}.
uniprot
proteins
function
FUNCTION: Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule (PubMed:27486780). Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (PubMed:23849778). {ECO:0000269|PubMed:23849778, ECO:0000269|PubMed:27486780}.
uniprot
proteins
mass_dalton
115679
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23849778
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
25186273
uniprot
proteins
pubmed
27486780
uniprot
proteins
sequence_length
1044
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:23849778}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:23849778}.
uniprot
proteins