Optc
entrez
269120
canonical
uniprot
Q920A0
canonical
ensembl
ENSMUSG00000010311
resolver
ensp
ENSMUSP00000115661
resolver
ensp
ENSMUSP00000117086
resolver
ensp
ENSMUSP00000120568
resolver
ensp
ENSMUSP00000123262
resolver
enst
ENSMUST00000124051
resolver
enst
ENSMUST00000126123
resolver
enst
ENSMUST00000149380
resolver
enst
ENSMUST00000153617
resolver
genesymbol
Optc
resolver
genesymbol_syn
Opt
resolver
uniprot
A0AB53B6B2
resolver
uniprot
A0ACM8Q8K1
resolver
uniprot
E9PUR1
resolver
uniprot
F6Z4X6
resolver
uniprot
G3UVW2
resolver
uniprot
Q14BF5
resolver
uniprot
Q3U5A9
resolver
uniprot
Q4KL49
resolver
uniprot
Q8K3K2
resolver
uniprot
Q91ZZ9
resolver
uniprot_entry
A0AB53B6B2_MOUSE
resolver
uniprot_entry
A0ACM8Q8K1_MOUSE
resolver
uniprot_entry
E9PUR1_MOUSE
resolver
uniprot_entry
G3UVW2_MOUSE
resolver
uniprot_entry
OPT_MOUSE
resolver
uniprot_entry
Q14BF5_MOUSE
resolver
uniprot_entry
Q4KL49_MOUSE
resolver
uniprot_sec
F6Z4X6
resolver
uniprot_sec
Q3U5A9
resolver
uniprot_sec
Q8K3K2
resolver
uniprot_sec
Q91ZZ9
resolver
amino_acid_sequence
MKFLAFLSLLSLVLQKAETASLLGEREREEQSPEEGDTYASLYVGNHTLSIEDYNEVIDLSNYEELADYGDQIPEAKISNLTLPTRTSPTSTVAQKTLSPNLTMAVPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDADLENIPPLPQMTTYLYARFNHISHIQAGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAFVALKKLQFLYLANNMLDSIPGPLPLSLRSLHLQNNMIETMESDTFCDTGEHRHERRQLEDIRLDGNPINLSLFPEAYFCLPRLPVGHFT
uniprot
proteins
function
FUNCTION: Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (PubMed:22159013). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (PubMed:29323130). {ECO:0000250|UniProtKB:P58874, ECO:0000269|PubMed:22159013, ECO:0000269|PubMed:29323130}.
uniprot
proteins
mass_dalton
36422
uniprot
proteins
post_translational_modification
PTM: O-glycosylated. {ECO:0000305}.; PTM: Sulfated on tyrosine residues. {ECO:0000250|UniProtKB:Q9UBM4}.; PTM: Proteolytically cleaved by MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, ADAMTS4, and ADAMTS5 (By similarity). Proteolytically cleaved by MMP13 (By similarity). {ECO:0000250|UniProtKB:P58874, ECO:0000250|UniProtKB:Q9UBM4}.
uniprot
proteins
protein_family
SLRP class III subfamily
uniprot
proteins
protein_family
Small leucine-rich proteoglycan (SLRP) family
uniprot
proteins
pubmed
11527931
uniprot
proteins
pubmed
12019215
uniprot
proteins
pubmed
22159013
uniprot
proteins
pubmed
29323130
uniprot
proteins
sequence_length
328
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P58874}.
uniprot
proteins