Ptrh2
entrez
217057
canonical
uniprot
Q8R2Y8
canonical
ensembl
ENSMUSG00000072582
resolver
ensp
ENSMUSP00000103656
resolver
ensp
ENSMUSP00000103657
resolver
enst
ENSMUST00000108021
resolver
enst
ENSMUST00000108022
resolver
genesymbol
Ptrh2
resolver
genesymbol_syn
Pth2
resolver
uniprot
Q8BI01
resolver
uniprot
Q8BI31
resolver
uniprot_entry
PTH2_MOUSE
resolver
uniprot_sec
Q8BI01
resolver
uniprot_sec
Q8BI31
resolver
amino_acid_sequence
MLSKFLTMEYLVHPGTLSLAAGVACGMCLGWGLRSHLGMFPQNSTSEANRDTETGTEASILGESGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAPDEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY
uniprot
proteins
ec_number
3.1.1.29
uniprot
proteins
function
FUNCTION: Peptidyl-tRNA hydrolase which releases tRNAs from the ribosome during protein synthesis. Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1. {ECO:0000250|UniProtKB:Q9Y3E5}.
uniprot
proteins
mass_dalton
19527
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. {ECO:0000250|UniProtKB:Q9Y3E5}.
uniprot
proteins
protein_family
PTH2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
181
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9Y3E5}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 10..32; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins