ICE2
entrez
79664
canonical
uniprot
Q659A1
canonical
ensembl
ENSG00000128915
resolver
ensp
ENSP00000261520
resolver
ensp
ENSP00000454162
resolver
ensp
ENSP00000544634
resolver
ensp
ENSP00000585400
resolver
ensp
ENSP00000675552
resolver
ensp
ENSP00000758552
resolver
enst
ENST00000561114
resolver
genesymbol
ICE2
resolver
genesymbol_syn
BRCC1
resolver
genesymbol_syn
NARG2
resolver
hgnc
HGNC:29885
resolver
uniprot
B2RU08
resolver
uniprot
H0YNU9
resolver
uniprot
Q05CT1
resolver
uniprot
Q3B7W6
resolver
uniprot
Q63HP4
resolver
uniprot
Q658Q0
resolver
uniprot
Q68CN8
resolver
uniprot
Q6IPW7
resolver
uniprot
Q6UX23
resolver
uniprot
Q71H65
resolver
uniprot
Q96CY5
resolver
uniprot
Q9HAA2
resolver
uniprot_entry
H0YNU9_HUMAN
resolver
uniprot_entry
ICE2_HUMAN
resolver
uniprot_sec
B2RU08
resolver
uniprot_sec
Q05CT1
resolver
uniprot_sec
Q3B7W6
resolver
uniprot_sec
Q63HP4
resolver
uniprot_sec
Q658Q0
resolver
uniprot_sec
Q68CN8
resolver
uniprot_sec
Q6IPW7
resolver
uniprot_sec
Q6UX23
resolver
uniprot_sec
Q71H65
resolver
uniprot_sec
Q96CY5
resolver
uniprot_sec
Q9HAA2
resolver
amino_acid_sequence
MSSKMVISEPGLNWDISPKNGLKTFFSRENYKDHSMAPSLKELRVLSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTIGMVLLPKPRVPYPRFSRFSQREQRSYVDLLVKYAKIPANSKAVGINKNDYLQYLDMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEKILRACIEQVKKYSEFYTLHEVTSLMGFFPFRVEMGLKLEKTLLALGSVKYVKTVFPSMPIKLQLSKDDIATIETSEQTAEAMHYDISKDPNAEKLVSRYHPQIALTSQSLFTLLNNHGPTYKEQWEIPVCIQVIPVAGSKPVKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEFISEMDMSCEVNECRKIESLENLYLDFDDDVTELETFGVTTTKVSKSPSPASTSTVPNMTDAPTAPKAGTTTVAPSAPDISANSRSLSQILMEQLQKEKQLVTGMDGGPEECKNKDDQGFESCEKVSNSDKPLIQDSDLKTSDALQLENSQEIETSNKNDMTIDILHADGERPNVLENLDNSKEKTVGSEAAKTEDTVLCSSDTDEECLIIDTECKNNSDGKTAVVGSNLSSRPASPNSSSGQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKVPELPLMNLENSKQPSVSEQLSGPSDSSSWPKSGWPSAFQKPKGRLPYELQDYVEDTSEYLAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISNLFNILQHILKKLSSLQEGSYLLSHAAEDSSLLIYKASDGKVTRTAYNLYKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLDTTTQQKIGGTRMPTRSHRNPVSMETKSSCLPAQQVETEGVAPHKRKIT
uniprot
proteins
function
FUNCTION: Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. {ECO:0000269|PubMed:23932780}.
uniprot
proteins
mass_dalton
110011
uniprot
proteins
protein_family
ICE2 family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15606750
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22195968
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23932780
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
982
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23932780}. Note=Colocalizes with COIL in subnuclear Cajal and histone locus bodies. Translocates in the LEC complex to Cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.
uniprot
proteins