Mthfs
entrez
107885
canonical
uniprot
Q9D110
canonical
ensembl
ENSMUSG00000066442
resolver
ensp
ENSMUSP00000082354
resolver
enst
ENSMUST00000085256
resolver
genesymbol
Mthfs
resolver
uniprot
B2KF82
resolver
uniprot_entry
MTHFS_MOUSE
resolver
uniprot_sec
B2KF82
resolver
amino_acid_sequence
MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQDEVETEVIIKDIFKQGKICFIPRYQFQSNHMDMVRLTSSEEIALLPKTSWNIHQPGEGDVREEALSTGGLDLIFLPGLGFDKDGNRLGRGKGYYDTYLKRCVQHQEVKPYTMALAFKEQICPQIPVDEHDMKVDEVLYEDSPAS
uniprot
proteins
ec_number
6.3.3.2
uniprot
proteins
function
FUNCTION: Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10-methenyltetrahydrofolate (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
23202
uniprot
proteins
protein_family
5-formyltetrahydrofolate cyclo-ligase family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
203
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins