Mpv17
entrez
17527
canonical
uniprot
P19258
canonical
ensembl
ENSMUSG00000107283
resolver
ensp
ENSMUSP00000115292
resolver
ensp
ENSMUSP00000143843
resolver
ensp
ENSMUSP00000144119
resolver
ensp
ENSMUSP00000144198
resolver
ensp
ENSMUSP00000144331
resolver
enst
ENSMUST00000154241
resolver
enst
ENSMUST00000200744
resolver
enst
ENSMUST00000200864
resolver
enst
ENSMUST00000201353
resolver
enst
ENSMUST00000202241
resolver
genesymbol
Mpv17
resolver
uniprot
E9Q1I6
resolver
uniprot
G3UVW1
resolver
uniprot_entry
E9Q1I6_MOUSE
resolver
uniprot_entry
G3UVW1_MOUSE
resolver
uniprot_entry
MPV17_MOUSE
resolver
amino_acid_sequence
MALWRAYQRALAAHPWKVQVLTAGSLMGVGDMISQQLVERRGLQQHQAGRTLTMVSLGCGFVGPVVGGWYKVLDHLIPGTTKVHALKKMLLDQGGFAPCFLGCFLPLVGILNGMSAQDNWAKLKRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAIVWNSYLSWKAHQF
uniprot
proteins
function
FUNCTION: Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis (By similarity). Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (PubMed:26760297). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (Probable). {ECO:0000250|UniProtKB:P39210, ECO:0000269|PubMed:26760297, ECO:0000305|PubMed:7957077}.
uniprot
proteins
mass_dalton
19686
uniprot
proteins
protein_family
Peroxisomal membrane protein PXMP2/4 family
uniprot
proteins
pubmed
11377883
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1696177
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26760297
uniprot
proteins
pubmed
7957077
uniprot
proteins
pubmed
9447939
uniprot
proteins
sequence_length
176
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P39210}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P39210}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 94..114; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..151; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins