Myocd
entrez
246297
canonical
uniprot
Q8R5I7
canonical
ensembl
ENSRNOG00000003669
resolver
ensembl
ENSRNOG00055031666
resolver
ensembl
ENSRNOG00060025678
resolver
ensp
ENSRNOP00000054372
resolver
ensp
ENSRNOP00000072988
resolver
ensp
ENSRNOP00055045336
resolver
ensp
ENSRNOP00060036991
resolver
enst
ENSRNOT00000057562
resolver
enst
ENSRNOT00000078675
resolver
enst
ENSRNOT00055054854
resolver
enst
ENSRNOT00060044636
resolver
genesymbol
Myocd
resolver
genesymbol_syn
Mycd
resolver
uniprot
A0A0G2K4C5
resolver
uniprot
Q7M6Y4
resolver
uniprot
Q8R5I8
resolver
uniprot_entry
A0A0G2K4C5_RAT
resolver
uniprot_entry
MYCD_RAT
resolver
uniprot_sec
Q7M6Y4
resolver
uniprot_sec
Q8R5I8
resolver
amino_acid_sequence
MTLLGSEHSLLIRRKFRSVLQLRLQQRRTQEQLANQGLIPPLKSPTEFHDPRKKLDSAKTEDSLRRKVRNRSDRASLVNMHILQASTAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEVSLSKAADAFAFEDDSSRDGLSPDQARSEDPQGSGGSTPDIKSTEAPLAGPLDTIQDLTPGSESDKNDTASQLSNQSDSGKQVLGPLSTPIPVHTAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQQQQQQQQQQQQQQQRFSYPGMHQAHLKEPNEQMTRNPNSSSTPLNNTPLSPVKNSLSGQTGVSSLKPGPLPPNLDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPFQDCAGNPVPNFGDITTVTFPVTPNTLPSYQSSPSGFYHFGSTSSSPPISPASSDLSAAGSLPDTFTDASPGFGLHASPVPACTDESLLSSLNGGSGPSEPDGLDSEKDKMLVEKQKVINQLTWKLRQEQRQVEELRMQLQKQKSGCNDQKPLPFLATTIKQEDVSSCPFAAQQASGKGQGHSSDSPPPACETAQLLPHCVESSGQTHVLSSTFLSPQCSPQHSPLGTLKSPQHISLPPSPNNHYFLASSSGAQRENHGVSSPNSSQGCAQMTGLQSSDKVGPTFSIPSPTFPKSSPTVPEITQPPSYEDAVKQQMTRSQQMDELLDVLIESGEMPADAREDHSCLQKIPKIPGSSCSPTTILPKSSASFEQASSGGQISFDHYATDSEEHLEVLLNSHSPIGKVSDVTLLKIGSEEPPFDGIMDGFPGKAAEDLFSAHELLPGPLSPMHTQLSPPSVDSSGLQLSFTESPWETMEWLDLTPPSSTPGFSNLTSSGPSIFNIDFLDVTDLNLNSPMDLHLQQW
uniprot
proteins
function
FUNCTION: Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes (By similarity). Plays a crucial role in cardiogenesis, urinary bladder development, and differentiation of the smooth muscle cell lineage (myogenesis) (By similarity). Positively regulates the transcription of genes involved in vascular smooth muscle contraction (PubMed:19237536). {ECO:0000250, ECO:0000269|PubMed:19237536}.
uniprot
proteins
mass_dalton
101872
uniprot
proteins
mutagenesis
MUTAGEN 534; /note="I->T: Abolishes homodimerization."; /evidence="ECO:0000269|PubMed:12756293"; MUTAGEN 537; /note="L->T: Abolishes homodimerization."; /evidence="ECO:0000269|PubMed:12756293"; MUTAGEN 541; /note="L->T: Abolishes homodimerization."; /evidence="ECO:0000269|PubMed:12756293
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated; by STUB1/CHIP at the C-terminus, leading to its degradation by the proteasome (PubMed:19237536). Phosphorylation by GSK3B is required for STUB1/CHIP-mediated ubiquitination (PubMed:19237536). {ECO:0000269|PubMed:19237536}.; PTM: Phosphorylation negatively regulates transcriptional activity (By similarity). Phosphorylated; by GSK3B (PubMed:19237536). {ECO:0000250|UniProtKB:Q8VIM5, ECO:0000269|PubMed:19237536}.
uniprot
proteins
pubmed
12392995
uniprot
proteins
pubmed
12663482
uniprot
proteins
pubmed
12756293
uniprot
proteins
pubmed
19237536
uniprot
proteins
pubmed
20385216
uniprot
proteins
sequence_length
938
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12392995, ECO:0000269|PubMed:19237536}.
uniprot
proteins