Myo1d
entrez
25485
canonical
uniprot
Q63357
canonical
ensembl
ENSRNOG00000003276
resolver
ensembl
ENSRNOG00055024739
resolver
ensembl
ENSRNOG00060031090
resolver
ensembl
ENSRNOG00065018964
resolver
ensp
ENSRNOP00000004609
resolver
ensp
ENSRNOP00055034828
resolver
ensp
ENSRNOP00060044775
resolver
ensp
ENSRNOP00065025460
resolver
enst
ENSRNOT00000004609
resolver
enst
ENSRNOT00055042653
resolver
enst
ENSRNOT00060053988
resolver
enst
ENSRNOT00065031903
resolver
genesymbol
Myo1d
resolver
genesymbol_syn
Myr4
resolver
uniprot
Q5PQU2
resolver
uniprot_entry
MYO1D_RAT
resolver
uniprot_sec
Q5PQU2
resolver
amino_acid_sequence
MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTVHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN
uniprot
proteins
function
FUNCTION: Unconventional myosin that functions as actin-based motor protein with ATPase activity (PubMed:12719468, PubMed:15853803). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (PubMed:26446290). {ECO:0000250|UniProtKB:F1PRN2, ECO:0000269|PubMed:12719468, ECO:0000269|PubMed:15853803, ECO:0000269|PubMed:26446290}.
uniprot
proteins
mass_dalton
116095
uniprot
proteins
protein_family
Myosin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
12719468
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15853803
uniprot
proteins
pubmed
24903835
uniprot
proteins
pubmed
26446290
uniprot
proteins
pubmed
30139971
uniprot
proteins
pubmed
8034741
uniprot
proteins
sequence_length
1006
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:24903835, ECO:0000269|PubMed:8034741}. Perikaryon {ECO:0000269|PubMed:8034741}. Cell projection, dendrite {ECO:0000269|PubMed:8034741}. Early endosome {ECO:0000250|UniProtKB:F1PRN2}. Cytoplasm, cell cortex {ECO:0000269|PubMed:26446290}. Note=Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane (PubMed:26446290). Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles (PubMed:8034741). {ECO:0000269|PubMed:26446290, ECO:0000269|PubMed:8034741}.
uniprot
proteins