KCNIP4
entrez
80333
canonical
uniprot
Q6PIL6
canonical
ensembl
ENSG00000185774
resolver
ensp
ENSP00000371583
resolver
ensp
ENSP00000371585
resolver
ensp
ENSP00000371587
resolver
ensp
ENSP00000399080
resolver
ensp
ENSP00000423257
resolver
ensp
ENSP00000494651
resolver
enst
ENST00000382149
resolver
genesymbol
KCNIP4
resolver
genesymbol_syn
CALP
resolver
genesymbol_syn
KCHIP4
resolver
hgnc
HGNC:30083
resolver
uniprot
A0A2R8YDJ5
resolver
uniprot
A8K4N3
resolver
uniprot
Q3YAB7
resolver
uniprot
Q3YAB8
resolver
uniprot
Q3YAB9
resolver
uniprot
Q3YAC0
resolver
uniprot
Q3YAC1
resolver
uniprot
Q3YAC2
resolver
uniprot
Q4W5G8
resolver
uniprot
Q8NEU0
resolver
uniprot
Q9BWT2
resolver
uniprot
Q9H294
resolver
uniprot
Q9H2A4
resolver
uniprot_entry
A0A2R8YDJ5_HUMAN
resolver
uniprot_entry
A8K4N3_HUMAN
resolver
uniprot_entry
KCIP4_HUMAN
resolver
uniprot_entry
Q3YAB7_HUMAN
resolver
uniprot_sec
Q3YAB8
resolver
uniprot_sec
Q3YAB9
resolver
uniprot_sec
Q3YAC0
resolver
uniprot_sec
Q3YAC1
resolver
uniprot_sec
Q3YAC2
resolver
uniprot_sec
Q4W5G8
resolver
uniprot_sec
Q8NEU0
resolver
uniprot_sec
Q9BWT2
resolver
uniprot_sec
Q9H294
resolver
uniprot_sec
Q9H2A4
resolver
amino_acid_sequence
MNVRRVESISAQLEEASSTGGFLYAQNSTKRSIKERLMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI
uniprot
proteins
function
FUNCTION: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. {ECO:0000250|UniProtKB:Q6PHZ8, ECO:0000269|PubMed:11847232, ECO:0000269|PubMed:18957440, ECO:0000269|PubMed:23576435}.
uniprot
proteins
mass_dalton
28729
uniprot
proteins
protein_family
Recoverin family
uniprot
proteins
pubmed
11805342
uniprot
proteins
pubmed
11847232
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16112838
uniprot
proteins
pubmed
18957440
uniprot
proteins
pubmed
22057399
uniprot
proteins
pubmed
23576435
uniprot
proteins
pubmed
24811166
uniprot
proteins
sequence_length
250
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11847232}; Peripheral membrane protein {ECO:0000305|PubMed:11847232}. Cytoplasm {ECO:0000269|PubMed:11847232, ECO:0000269|PubMed:23576435}. Peroxisome {ECO:0000269|PubMed:22057399}.; SUBCELLULAR LOCATION: [Isoform 4]: Endoplasmic reticulum {ECO:0000269|PubMed:23576435}.
uniprot
proteins