Rhot1
entrez
59040
canonical
uniprot
Q8BG51
canonical
ensembl
ENSMUSG00000017686
resolver
ensp
ENSMUSP00000017831
resolver
ensp
ENSMUSP00000057669
resolver
ensp
ENSMUSP00000076664
resolver
ensp
ENSMUSP00000090533
resolver
ensp
ENSMUSP00000117941
resolver
ensp
ENSMUSP00000270994
resolver
ensp
ENSMUSP00000271025
resolver
genesymbol
Rhot1
resolver
genesymbol_syn
Arht1
resolver
uniprot
Q3TJB7
resolver
uniprot
Q3UGU4
resolver
uniprot
Q5SYC3
resolver
uniprot
Q5SYC6
resolver
uniprot
Q8BLW3
resolver
uniprot
Q8BMH1
resolver
uniprot
Q922N0
resolver
uniprot
Q9D2R1
resolver
uniprot
Q9JKB9
resolver
uniprot_entry
MIRO1_MOUSE
resolver
uniprot_sec
Q3TJB7
resolver
uniprot_sec
Q3UGU4
resolver
uniprot_sec
Q5SYC3
resolver
uniprot_sec
Q5SYC6
resolver
uniprot_sec
Q8BLW3
resolver
uniprot_sec
Q8BMH1
resolver
uniprot_sec
Q922N0
resolver
uniprot_sec
Q9D2R1
resolver
uniprot_sec
Q9JKB9
resolver
amino_acid_sequence
MRAGRVRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQKKIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAETICDVVCLVYDVTNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEHSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHVTQADLKSSTFWLRASFGATVFAVVGFAMYRALLKQR
uniprot
proteins
ec_number
3.6.5.-
uniprot
proteins
function
FUNCTION: Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Promotes mitochondrial fission during high calcium conditions. Can hydrolyze GTP, ATP and UTP (By similarity). {ECO:0000250|UniProtKB:Q8IXI2}.
uniprot
proteins
mass_dalton
72242
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30 (By similarity). {ECO:0000250|UniProtKB:Q8IXI2}.; PTM: Acetylation on Lys-105 decreases sensitivity of mitochondrial transport to elevated Ca(2+) levels, increases mitochondrial transport and promotes axon growth. Deacetylated by HDAC6 which blocks mitochondrial transport and mediates axon growth inhibition. {ECO:0000250|UniProtKB:A1L1L6}.
uniprot
proteins
protein_family
Mitochondrial Rho GTPase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28009275
uniprot
proteins
sequence_length
631
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8IXI2}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q8IXI2}. Note=Colocalizes with MGARP and RHOT2 at the mitochondria. {ECO:0000250|UniProtKB:Q8IXI2}.
uniprot
proteins
transmembrane_region
TRANSMEM 606..628; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins