PLD2
entrez
5338
canonical
uniprot
O14939
canonical
ensembl
ENSG00000129219
resolver
ensp
ENSP00000263088
resolver
ensp
ENSP00000459571
resolver
ensp
ENSP00000689049
resolver
ensp
ENSP00000689057
resolver
genesymbol
PLD2
resolver
hgnc
HGNC:9068
resolver
uniprot
I3L2C9
resolver
uniprot
O43540
resolver
uniprot
O43579
resolver
uniprot
O43580
resolver
uniprot
Q6PGR0
resolver
uniprot
Q96BY3
resolver
uniprot_entry
PLD2_HUMAN
resolver
uniprot_sec
I3L2C9
resolver
uniprot_sec
O43540
resolver
uniprot_sec
O43579
resolver
uniprot_sec
O43580
resolver
uniprot_sec
Q6PGR0
resolver
uniprot_sec
Q96BY3
resolver
activity_regulation
ACTIVITY REGULATION: Stimulated by phosphatidylinositol 4,5-bisphosphate and slightly activated by the ADP-ribosylation factor-1 (ARF-1). {ECO:0000269|PubMed:9582313}.
uniprot
proteins
amino_acid_sequence
MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
uniprot
proteins
ec_number
3.1.4.4
uniprot
proteins
function
FUNCTION: Function as phospholipase selective for phosphatidylcholine (PubMed:9582313). May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity). {ECO:0000250|UniProtKB:P97813, ECO:0000269|PubMed:9582313}.
uniprot
proteins
mass_dalton
105987
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by FGR. {ECO:0000250|UniProtKB:P70498}.
uniprot
proteins
protein_family
Phospholipase D family
uniprot
proteins
pubmed
11032811
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
9582313
uniprot
proteins
pubmed
9761774
uniprot
proteins
sequence_length
933
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P97813}; Lipid-anchor {ECO:0000250|UniProtKB:P97813}.
uniprot
proteins