Tent4b
entrez
214627
canonical
uniprot
Q68ED3
canonical
ensembl
ENSMUSG00000036779
resolver
ensp
ENSMUSP00000067971
resolver
ensp
ENSMUSP00000112608
resolver
ensp
ENSMUSP00000112766
resolver
ensp
ENSMUSP00000160021
resolver
ensp
ENSMUSP00000218019
resolver
ensp
ENSMUSP00000218020
resolver
enst
ENSMUST00000066748
resolver
enst
ENSMUST00000118952
resolver
enst
ENSMUST00000119033
resolver
enst
ENSMUST00000249924
resolver
genesymbol
Tent4b
resolver
genesymbol_syn
Papd5
resolver
uniprot
A6H635
resolver
uniprot
B7ZMU2
resolver
uniprot
E9QJT6
resolver
uniprot
F8WI26
resolver
uniprot
Q8C0K6
resolver
uniprot_entry
B7ZMU2_MOUSE
resolver
uniprot_entry
E9QJT6_MOUSE
resolver
uniprot_entry
F8WI26_MOUSE
resolver
uniprot_entry
PAPD5_MOUSE
resolver
uniprot_sec
A6H635
resolver
uniprot_sec
Q8C0K6
resolver
amino_acid_sequence
MFRSGERPLGGLAVPAEQRDFLPLETTNNNNNHHQPAAWARRASAGPSASPVPSAPSSPRPAAALPASESTDPASGSSNKRKRDNKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLQNRPEPSCNGNGVTLIVDTQQLDKCNNNLSEEKEALGKCRSNASEPLSKHSSNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQLLCRPPTVTRVGSQDVSLEVSQAVGKMQSTQTTNTPNNANKSQHGSARLFRSSSKGFQGTAQTSHGALMTSKQHQGKSNTQYYHGKKRRHKRDAPLSELCR
uniprot
proteins
ec_number
2.7.7.-
uniprot
proteins
ec_number
2.7.7.19
uniprot
proteins
function
FUNCTION: Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active deadenylation (By similarity). Also functions as a catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion (By similarity). {ECO:0000250|UniProtKB:Q8NDF8}.
uniprot
proteins
mass_dalton
69704
uniprot
proteins
protein_family
DNA polymerase type-B-like family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
633
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8NDF8}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q8NDF8}. Cytoplasm {ECO:0000250|UniProtKB:Q8NDF8}. Note=Predominantly expressed in the cytoplasm. {ECO:0000250|UniProtKB:Q8NDF8}.
uniprot
proteins