POLR2I
entrez
5438
canonical
uniprot
P36954
canonical
ensembl
ENSG00000105258
resolver
ensp
ENSP00000221859
resolver
enst
ENST00000221859
resolver
genesymbol
POLR2I
resolver
hgnc
HGNC:9196
resolver
uniprot
B2R5J2
resolver
uniprot
Q6NW05
resolver
uniprot_entry
RPB9_HUMAN
resolver
uniprot_sec
B2R5J2
resolver
uniprot_sec
Q6NW05
resolver
amino_acid_sequence
MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE
uniprot
proteins
function
FUNCTION: Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. POLR2I/RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template. {ECO:0000250|UniProtKB:P27999, ECO:0000269|PubMed:27193682, ECO:0000269|PubMed:30190596, ECO:0000269|PubMed:9852112}.
uniprot
proteins
mass_dalton
14523
uniprot
proteins
protein_family
Archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
27193682
uniprot
proteins
pubmed
30190596
uniprot
proteins
pubmed
8265347
uniprot
proteins
pubmed
9852112
uniprot
proteins
sequence_length
125
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:9852112}.
uniprot
proteins