Sln
entrez
367086
canonical
uniprot
Q6SLE7
canonical
ensembl
ENSRNOG00000009047
resolver
ensembl
ENSRNOG00055029080
resolver
ensembl
ENSRNOG00060015147
resolver
ensembl
ENSRNOG00065016582
resolver
ensp
ENSRNOP00000011970
resolver
ensp
ENSRNOP00055041441
resolver
ensp
ENSRNOP00060020775
resolver
ensp
ENSRNOP00065021748
resolver
enst
ENSRNOT00000011974
resolver
enst
ENSRNOT00055050355
resolver
enst
ENSRNOT00060025962
resolver
enst
ENSRNOT00065027627
resolver
genesymbol
Sln
resolver
uniprot_entry
SARCO_RAT
resolver
amino_acid_sequence
MERSTQELFINFTVVLITVLLMWLLVRSYQY
uniprot
proteins
function
FUNCTION: Reversibly inhibits the activity of ATP2A1/SERCA1 and ATP2A2/SERCA2 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Also inhibits the activity of ATP2A3/SERCA3. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis (By similarity). {ECO:0000250|UniProtKB:O00631, ECO:0000250|UniProtKB:Q9CQD6}.
uniprot
proteins
mass_dalton
3808
uniprot
proteins
protein_family
Sarcolipin family
uniprot
proteins
sequence_length
31
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9CQD6}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P42532}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..26; /note="Helical"; /evidence="ECO:0000250
uniprot
proteins