TLX1
entrez
3195
canonical
uniprot
P31314
canonical
ensembl
ENSG00000107807
resolver
ensp
ENSP00000359215
resolver
ensp
ENSP00000434914
resolver
genesymbol
TLX1
resolver
genesymbol_syn
HOX11
resolver
genesymbol_syn
TCL3
resolver
hgnc
HGNC:5056
resolver
uniprot
A1L4G3
resolver
uniprot
O75699
resolver
uniprot
Q5VXP2
resolver
uniprot
Q9HCA0
resolver
uniprot
Q9UD59
resolver
uniprot_entry
TLX1_HUMAN
resolver
uniprot_sec
A1L4G3
resolver
uniprot_sec
O75699
resolver
uniprot_sec
Q5VXP2
resolver
uniprot_sec
Q9HCA0
resolver
uniprot_sec
Q9UD59
resolver
amino_acid_sequence
MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
uniprot
proteins
disease_involvement
DISEASE: Note=A chromosomal aberration involving TLX1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(10;14)(q24;q11) with TCRD. {ECO:0000269|PubMed:1676542, ECO:0000269|PubMed:1681546, ECO:0000269|PubMed:1717256}.
uniprot
proteins
function
FUNCTION: Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
uniprot
proteins
mass_dalton
34365
uniprot
proteins
pubmed
10393251
uniprot
proteins
pubmed
1352396
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1676542
uniprot
proteins
pubmed
1681546
uniprot
proteins
pubmed
1717256
uniprot
proteins
pubmed
17303350
uniprot
proteins
pubmed
19559479
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
7518789
uniprot
proteins
pubmed
9778044
uniprot
proteins
sequence_length
330
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins