St8sia1
entrez
20449
canonical
uniprot
Q64687
canonical
ensembl
ENSMUSG00000030283
resolver
ensp
ENSMUSP00000032421
resolver
enst
ENSMUST00000032421
resolver
genesymbol
St8sia1
resolver
genesymbol_syn
Siat8
resolver
genesymbol_syn
Siat8a
resolver
uniprot
Q3V3B1
resolver
uniprot
Q8K1C1
resolver
uniprot_entry
Q3V3B1_MOUSE
resolver
uniprot_entry
SIA8A_MOUSE
resolver
uniprot_sec
Q8K1C1
resolver
amino_acid_sequence
MSPCGRALHTSRGAMAMLARKFPRTRLPVGASALCVVVLCWLYIFPVYRLPNEKEIVQGVLAQRTAWRTNQTSASLFRRQMEDCCDPAHLFAMTKMNSPMGKSLWYDGELLYSFTIDNSTYSLFPQATPFQLPLKKCAVVGNGGILKMSGCGRQIDEANFVMRCNLPPLSSEYTRDVGSKTQLVTANPSIIRQRFENLLWSRKKFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLKDVGANQTVLFANPNFLRNIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVSIYGFWPFSVNMQGDPISHHYYDNVLPFSGYHAMPEEFLQLWYLHKIGALRMQLDPCEEPSPQPTS
uniprot
proteins
ec_number
2.4.3.8
uniprot
proteins
function
FUNCTION: Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphingolipds that contain one or more residues of sialic acid (PubMed:8910600). Can catalyze the addition of a second alpha-2,8- sialic acid to GD3 to form GT3 (PubMed:8910600). Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively (PubMed:8910600). {ECO:0000269|PubMed:8910600}.
uniprot
proteins
mass_dalton
40324
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.; PATHWAY: Lipid metabolism; sphingolipid metabolism.
uniprot
proteins
protein_family
Glycosyltransferase 29 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15843597
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8910600
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 29..47; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins