Sult1c2
entrez
171072
canonical
uniprot
Q9WUW8
canonical
ensembl
ENSRNOG00000065530
resolver
ensembl
ENSRNOG00000067413
resolver
ensembl
ENSRNOG00055018845
resolver
ensembl
ENSRNOG00055018873
resolver
ensembl
ENSRNOG00060023965
resolver
ensembl
ENSRNOG00060025885
resolver
ensembl
ENSRNOG00065014883
resolver
ensembl
ENSRNOG00065014894
resolver
ensp
ENSRNOP00000062844
resolver
ensp
ENSRNOP00000069149
resolver
ensp
ENSRNOP00055025967
resolver
ensp
ENSRNOP00055026032
resolver
ensp
ENSRNOP00060034408
resolver
ensp
ENSRNOP00060037168
resolver
ensp
ENSRNOP00065019204
resolver
ensp
ENSRNOP00065019222
resolver
enst
ENSRNOT00000082579
resolver
enst
ENSRNOT00055032109
resolver
enst
ENSRNOT00055032174
resolver
enst
ENSRNOT00060041524
resolver
enst
ENSRNOT00060044818
resolver
enst
ENSRNOT00065024611
resolver
enst
ENSRNOT00065024633
resolver
genesymbol
Sult1c2
resolver
genesymbol_syn
Sultk1
resolver
uniprot
F1LZL1
resolver
uniprot
Q3ZAV3
resolver
uniprot_entry
ST1C2_RAT
resolver
uniprot_sec
F1LZL1
resolver
uniprot_sec
Q3ZAV3
resolver
amino_acid_sequence
MALAPELSRQTKLKEVAGIPLQAPTVDNWSQIQTFKAKPDDLLICTYPKSGTTWIQEIVDMIEQNGDVEKCQRTIIQHRHPFIEWARPPQPSGVDKANAMPAPRILRTHLPTQLLPPSFWTNNCKFLYVARNAKDCMVSYYHFYRMSQVLPDPGTWNEYFETFINGKVSWGSWFDHVKGWWEIRDRYQILFLFYEDMKRDPKREIQKVMQFMGKNLDEEVVDKIVLETSFEKMKENPMTNRSTVPKSVLDQSISPFMRKGTVGDWKNHFTVAQNDRFDEIYKQKMGGTSLNFCMEL
uniprot
proteins
ec_number
2.8.2.1
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the sulfate conjugation of phenolic compounds (PubMed:10872834). Does not transfer sulfate to steroids, dopamine, acetaminophen, or alpha-naphthol (PubMed:10872834). Except in mitochondria, where it can add sulfate to cholesterol producing cholesterol sulfate, which alters mitochondrial membrane organization, and impacts protein complex mobility increasing state-III respiration, thereby modulating mitochondrial respiration (PubMed:39194960). Catalyzes the sulfation of the carcinogenic N-hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis (By similarity). {ECO:0000250|UniProtKB:O00338, ECO:0000269|PubMed:10872834, ECO:0000269|PubMed:39194960}.
uniprot
proteins
mass_dalton
34731
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
10872834
uniprot
proteins
pubmed
12164856
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
39194960
uniprot
proteins
sequence_length
296
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O46503}. Lysosome {ECO:0000269|PubMed:10872834}. Mitochondrion {ECO:0000269|PubMed:39194960}.
uniprot
proteins