TAS2R40
entrez
259286
canonical
uniprot
P59535
canonical
ensembl
ENSG00000221937
resolver
ensp
ENSP00000386210
resolver
enst
ENST00000408947
resolver
genesymbol
TAS2R40
resolver
genesymbol_syn
GPR60
resolver
hgnc
HGNC:18885
resolver
uniprot
A4D2I2
resolver
uniprot
Q645W6
resolver
uniprot_entry
T2R40_HUMAN
resolver
uniprot_sec
A4D2I2
resolver
uniprot_sec
Q645W6
resolver
amino_acid_sequence
MATVNTDATDKDISKFKVTFTLVVSGIECITGILGSGFITAIYGAEWARGKTLPTGDRIMLMLSFSRLLLQIWMMLENIFSLLFRIVYNQNSVYILFKVITVFLNHSNLWFAAWLKVFYCLRIANFNHPLFFLMKRKIIVLMPWLLRLSVLVSLSFSFPLSRDVFNVYVNSSIPIPSSNSTEKKYFSETNMVNLVFFYNMGIFVPLIMFILAATLLILSLKRHTLHMGSNATGSRDPSMKAHIGAIKATSYFLILYIFNAIALFLSTSNIFDTYSSWNILCKIIMAAYPAGHSVQLILGNPGLRRAWKRFQHQVPLYLKGQTL
uniprot
proteins
function
FUNCTION: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
uniprot
proteins
mass_dalton
36812
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
11696554
uniprot
proteins
pubmed
12139982
uniprot
proteins
pubmed
12379855
uniprot
proteins
pubmed
12581520
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15496549
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 15..35; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 59..79; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 101..121; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 141..162; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 191..211; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 248..268; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 277..297; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins