Card14
entrez
170720
canonical
uniprot
Q99KF0
canonical
ensembl
ENSMUSG00000013483
resolver
ensp
ENSMUSP00000053665
resolver
ensp
ENSMUSP00000101857
resolver
ensp
ENSMUSP00000298661
resolver
enst
ENSMUST00000053245
resolver
enst
ENSMUST00000106250
resolver
genesymbol
Card14
resolver
genesymbol_syn
Bimp2
resolver
uniprot_entry
CAR14_MOUSE
resolver
amino_acid_sequence
MAELCRMDSTLTALDEEMLWDMLESHRCRIVQSICPSRLTPYLRQAKVLGQLDEEEILHSSRFTNSAMRVGHLLDLLKARGKNGAIAFLESLKFHNPDVYTLVTGLQSDIDFSTFSGLMETSKLTECLAGAISSLQEELAQEKAQKEVLLRRCQQLKERLGLAEAHAEGLRQLEVDHSRMKREVSTHFHEVLKLKDEMLNLSLHYSNALREKELAATRCHSLQEELYLVKQELQRASLVSSCERESRERSLKMASNLEPQGEELNRLKEENEKLRSMTFSLVEKDILEQSLDEARESKQELVDRIHSLRERAVAAERQQKQYWEEKEQTLLQFRKTQVDCELYKEKMTMLQGQVAELQKERDQAYTARDRAQMEISQRLVEKDALRRRVFELTEQVCELRTQLRRLQAEAPGGPKQEAGARELCLRGKQRLVRMHAVCPPDDSDCSLLSSTESRLWWDLNSTSSREQMDSFRSSSPMPPSQQSLYKRVAEDFLEDPESLSFPEVLEMRLQGATVDDTDTDLEFEMIDGADLSQTEDSLQGSSRSLNVSESSVPVRRRPARKILSQVTVLAFQGDALLEQIGVIGGNLTGIFIHRVTPGSAADEMALRPGTQIMMVDYKPTKPSLRATLENTTLEQAVGLLRRVNGSCYLSVKINTEGYKNLIQDLDAKVVTSGDSFYIRVNLAMQRGGDGELQTHCNDILHVTDTMFQGRSCWHAHHVNPYTMKDMEPGTIPNYSQAQQQLLALIQDMTQRCTVPRKPPGGPQKLVRIVSVDKAAVSPLTSSFDQSQWDSGKEEGGPSVCFWSESCFTLAPYTLVHPHRPARPRPVLFVPRLVGRILGKKLCLLQGFKQCSAEYLSQEEYATWSQRGDIIQEGESIGDHHWITRHAVESLMNMSTHALLDVRLDSVRVLHRMDMFPIIIHVSVNEKTAKKLRKGLHRLGSSEEQFLEVARQEEGELDRVPCLYSSLAPDSWSDLDSLLSCVRLAIADEQKKVVWTESPC
uniprot
proteins
function
FUNCTION: Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. {ECO:0000250|UniProtKB:Q9BXL6}.
uniprot
proteins
mass_dalton
113497
uniprot
proteins
pubmed
11387339
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
999
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BXL6}.
uniprot
proteins