Trarg1
entrez
237858
canonical
uniprot
Q8C838
canonical
ensembl
ENSMUSG00000046275
resolver
ensp
ENSMUSP00000061634
resolver
enst
ENSMUST00000062024
resolver
genesymbol
Trarg1
resolver
genesymbol_syn
Tusc5
resolver
uniprot_entry
TARG1_MOUSE
resolver
amino_acid_sequence
MANPAQPPLQDPGSTSPLELPEMEKLLTKVENKDDQALNLSKSLSGALDLEQNGHSLPFKVISEGHRQPSLSGSPSRVSSRRASSVITTSYAQDQEAPKDYLVLAIASCFCPVWPLNLIPLIFSIMSRSSVQQGDLDGARRLGRLARLLSITFIILGIVIIIVAVTVNFTVPK
uniprot
proteins
function
FUNCTION: Regulates insulin-mediated adipose tissue glucose uptake and transport by modulation of SLC2A4 recycling. Not required for SLC2A4 membrane fusion upon an initial stimulus, but rather is necessary for proper protein recycling during prolonged insulin stimulation. {ECO:0000269|PubMed:26240143, ECO:0000269|PubMed:26629404}.
uniprot
proteins
mass_dalton
18719
uniprot
proteins
protein_family
CD225/Dispanin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22363774
uniprot
proteins
pubmed
26240143
uniprot
proteins
pubmed
26629404
uniprot
proteins
pubmed
29787242
uniprot
proteins
sequence_length
173
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26240143, ECO:0000269|PubMed:26629404, ECO:0000269|PubMed:29787242}; Single-pass membrane protein {ECO:0000305|PubMed:29787242}. Endomembrane system {ECO:0000269|PubMed:26240143, ECO:0000269|PubMed:26629404}; Single-pass membrane protein {ECO:0000305|PubMed:29787242}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:26240143}. Note=Shifts from low-density microsome vesicles to the cell membrane upon insulin stimulation. {ECO:0000269|PubMed:26240143, ECO:0000269|PubMed:26629404}.
uniprot
proteins
transmembrane_region
TRANSMEM 151..171; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins