Ckap4
entrez
216197
canonical
uniprot
Q8BMK4
canonical
ensembl
ENSMUSG00000046841
resolver
ensp
ENSMUSP00000050336
resolver
enst
ENSMUST00000053871
resolver
genesymbol
Ckap4
resolver
uniprot
B2RRB4
resolver
uniprot
Q8BTK8
resolver
uniprot
Q8R3F2
resolver
uniprot_entry
CKAP4_MOUSE
resolver
uniprot_sec
B2RRB4
resolver
uniprot_sec
Q8BTK8
resolver
uniprot_sec
Q8R3F2
resolver
amino_acid_sequence
MPSAKQRGSKGGHGAASPSDKGAHPSGGADDVAKKPPAAPQQPQPPAPHPPQHPQNQAHRGGHRGRSSAATANASSASCSRRLGRVLNFLFYLSLVAAAAFSGWYVHHVLEEVQQVRRGHQDFSRQRDELGQGLQGVEQKVQSLQATFGTFESLLRNSQHKQDLTEKAVKEGESELNRISEVLQKLQNEILKDLSDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTDVQKRSQKEINEVKMKVASLEESKGDRSQDVKTLKDAVKEVQASMMSRERDIEALKSSLQTMESDVYTEVRELVSLKQEQQAFKQAADSERLALQALTEKLLRSEESSSRLPEDIRRLEEELQQLKVGAHGSEEGAVFKDSKALEELQRQIEGLGARLQYVEDGVYSMQVASARHTESLESLLSKSQEYEQRLAMLQEHVGNLGSSSDLASTVRSLGETQLALSSDLKELKQSLGELPGTVESLQEQVLSLLSQDQAQAEGLPPQDFLDRLSSLDNLKSSVSQVESDLKMLRTAVDSLVAYSVKIETNENNLESAKGLLDDLRNDLDRLFLKVEKIHEKI
uniprot
proteins
function
FUNCTION: High-affinity epithelial cell surface receptor for APF. {ECO:0000250}.; FUNCTION: Mediates the anchoring of the endoplasmic reticulum to microtubules. {ECO:0000250}.
uniprot
proteins
mass_dalton
63692
uniprot
proteins
post_translational_modification
PTM: Reversibly palmitoylated. Palmitoylation at Cys-79 by DHHC2 is required for its trafficking from the ER to the plasma membrane and for its perinuclear localization (By similarity). {ECO:0000250}.; PTM: Increased phosphorylation during mitosis prevents binding to microtubules. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
32075961
uniprot
proteins
sequence_length
575
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:32075961}; Single-pass type II membrane protein {ECO:0000305}. Cell membrane {ECO:0000250|UniProtKB:Q07065}; Single-pass type II membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Translocates to the perinuclear region upon APF-stimulation. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 86..108; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins