Cntnap2
entrez
66797
canonical
uniprot
Q9CPW0
canonical
ensembl
ENSMUSG00000039419
resolver
ensp
ENSMUSP00000110288
resolver
ensp
ENSMUSP00000143528
resolver
enst
ENSMUST00000114641
resolver
genesymbol
Cntnap2
resolver
genesymbol_syn
Kiaa0868
resolver
uniprot
E9QNF7
resolver
uniprot
Q3SYI6
resolver
uniprot
Q6P2K4
resolver
uniprot
Q6ZQ31
resolver
uniprot_entry
CNTP2_MOUSE
resolver
uniprot_entry
E9QNF7_MOUSE
resolver
uniprot_entry
Q3SYI6_MOUSE
resolver
uniprot_sec
Q6P2K4
resolver
uniprot_sec
Q6ZQ31
resolver
amino_acid_sequence
MVMSLRAGYRAALSLWILSSFICRAWTAPSTFQKCDEPLISGLPHVSFSSSSSLSSSYAPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDSVVRHDLQHAVVARYVRIVPLDWNGEGHIGLRAEVYGCAYWADVINFDGHGVLPYRFRNKKMKTLKDVIALKFKTSESEGVLLHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVTSGSLLDDHHWHSVLIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSNRKNFKGCMESINYNGVNITDLARRKKLGPSNMGNLSFSCVEPYTVPVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPSGLLLFSHFADNLGNVEIDLVESKVGVHINNTQTKTSQIDISSGSGLNDGQWHEVRFLAKENFAVLTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNHMNNASYSALQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVTIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIVSHDLQMQTTVVGYNPEKYSVTQLIYSASMDQISAITSSAEYCEQYVSYFCRMSRLLNTPDGSPYTWWVGKANEKHYYWGGSEPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLIPRGVFLENLGNTDFIKLELKSATEVSFSFDVGNGPVEIVVRSPSPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFKSGCSGHCTSYGANCENGGKCIEKYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPAVTARDTGSRAENSADQQQHLAPDLAQEQIHFSFSTTKAPCILLYVSSLTTDFLAVLVKPTGNLQIRYNLGGTREPFNIDVDHRNMANGQPHSVNITRHERTIILKLDHYPAVGYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNHIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI
uniprot
proteins
function
FUNCTION: Required for gap junction formation (By similarity). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons (PubMed:25378149). Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction (Probable) (PubMed:25378149). {ECO:0000250|UniProtKB:Q9UHC6, ECO:0000269|PubMed:25378149, ECO:0000305|PubMed:11567047}.
uniprot
proteins
mass_dalton
148197
uniprot
proteins
protein_family
Neurexin family
uniprot
proteins
pubmed
11567047
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25378149
uniprot
proteins
sequence_length
1332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:11567047}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000269|PubMed:11567047, ECO:0000269|PubMed:25378149}. Cell junction, paranodal septate junction {ECO:0000269|PubMed:25378149}. Note=Expressed in the juxtaparadonal region. {ECO:0000269|PubMed:25378149}.
uniprot
proteins
transmembrane_region
TRANSMEM 1263..1283; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins