Lipn
entrez
70166
canonical
uniprot
Q3U4B4
canonical
ensembl
ENSMUSG00000024770
resolver
ensp
ENSMUSP00000025682
resolver
enst
ENSMUST00000025682
resolver
genesymbol
Lipn
resolver
genesymbol_syn
Lipl4
resolver
uniprot_entry
LIPN_MOUSE
resolver
amino_acid_sequence
MPMMWLFLTTACLIPGTLSAGGFLDFENKVNPEVWMNASEIIMYNGYPSEEYDVTTADGYILAINRIPHGRAQTGQTGPRPVVYMQHALFADNAYWLENFANGSLGFILADAGYDVWMGNSRGNTWSRRHKTLSANEEKFWAFSFNEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPVISFKYPTSVFTNLFLLPKSIIKLVFGTKGVLLEDKNARMSFITFCNQKLLQPLCSEFMSLWAGFNKKNMNMSRLDVYMAHAPTGSSIQNMLHIKQLYRSDEFRAYDWGSEAENMNHYNQSYPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPDWNHFDFVWGLDAPQRLYSKIISLMKEYF
uniprot
proteins
ec_number
3.1.1.13
uniprot
proteins
ec_number
3.1.1.3
uniprot
proteins
function
FUNCTION: Plays a highly specific role in the last step of keratinocyte differentiation. Contains two distinct domains: the alpha/beta hydrolase fold and the abhydrolase-associated lipase region, also features the consensus sequence of the active site of a genuine lipase. May have an essential function in lipid metabolism of the most differentiated epidermal layers. {ECO:0000250|UniProtKB:Q5VXI9, ECO:0000269|PubMed:20598663}.
uniprot
proteins
mass_dalton
45744
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
Lipase family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20598663
uniprot
proteins
sequence_length
400
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins