Sucla2
entrez
20916
canonical
uniprot
Q9Z2I9
canonical
ensembl
ENSMUSG00000022110
resolver
ensp
ENSMUSP00000022706
resolver
ensp
ENSMUSP00000123765
resolver
enst
ENSMUST00000022706
resolver
enst
ENSMUST00000160507
resolver
genesymbol
Sucla2
resolver
uniprot
Q3TVH1
resolver
uniprot
Q8BGS6
resolver
uniprot_entry
SUCB1_MOUSE
resolver
uniprot_sec
Q3TVH1
resolver
uniprot_sec
Q8BGS6
resolver
amino_acid_sequence
MAASMFYGRQLAAAALRSHRPQTTLRAAAQVLGNSGLFNKHGLQVQQQQQRTLSLHEYLSMELLQEAGVSVPKGFVAKSSDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFTSGLKGGVKIVFSPEEAKAVSSQMIGQKLITKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSAQGGVNIEDVAAENPEAIVKEPIDIVEGIKKEQAVTLAQKMGFPSNIVDSAAENMIKLYNLFLKYDATMVEINPMVEDSDGKVLCMDAKINFDSNSAYRQKKIFDLQDWSQEDERDKEAANADINYIGLDGSIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVQQVTEAFKLITSDKKVQAILVNIFGGIMRCDVIAQGIVMAVKDLEIRIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAAKMVVKLSEIVTLAKEAHVDVKFQLPI
uniprot
proteins
ec_number
6.2.1.-
uniprot
proteins
ec_number
6.2.1.5
uniprot
proteins
ec_number
6.2.1.9
uniprot
proteins
function
FUNCTION: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Also able to act as an ATP-specific itaconyl- and malyl-CoA synthetase. {ECO:0000255|HAMAP-Rule:MF_03220}.
uniprot
proteins
mass_dalton
50114
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_03220}.
uniprot
proteins
protein_family
ATP-specific subunit beta subfamily
uniprot
proteins
protein_family
Succinate/malate CoA ligase beta subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17114649
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
9765291
uniprot
proteins
sequence_length
463
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03220}.
uniprot
proteins