ACSM5
entrez
54988
canonical
uniprot
Q6NUN0
canonical
ensembl
ENSG00000183549
resolver
ensp
ENSP00000327916
resolver
ensp
ENSP00000460112
resolver
ensp
ENSP00000579310
resolver
ensp
ENSP00000788540
resolver
genesymbol
ACSM5
resolver
genesymbol_syn
MACS3
resolver
hgnc
HGNC:26060
resolver
uniprot
Q96AV1
resolver
uniprot
Q96CX8
resolver
uniprot
Q9NWV3
resolver
uniprot_entry
ACSM5_HUMAN
resolver
uniprot_sec
Q96AV1
resolver
uniprot_sec
Q96CX8
resolver
uniprot_sec
Q9NWV3
resolver
amino_acid_sequence
MRPWLRHLVLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK
uniprot
proteins
ec_number
6.2.1.2
uniprot
proteins
function
FUNCTION: Acyl-CoA synthetase that catalyzes the ATP-dependent activation of fatty acids to their corresponding acyl-CoA thioesters, the first committed step in fatty acid metabolism (By similarity). Negatively regulates lipid accumulation via inhibition of FABP4-PPARgamma signaling (PubMed:37957699). {ECO:0000250|UniProtKB:Q08AH1, ECO:0000269|PubMed:37957699}.
uniprot
proteins
mass_dalton
64760
uniprot
proteins
protein_family
ATP-dependent AMP-binding enzyme family
uniprot
proteins
pubmed
12654705
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
27351777
uniprot
proteins
pubmed
37957699
uniprot
proteins
sequence_length
579
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q91VA0}.
uniprot
proteins