Med28
entrez
66999
canonical
uniprot
Q920D3
canonical
ensembl
ENSMUSG00000015804
resolver
ensp
ENSMUSP00000115882
resolver
enst
ENSMUST00000156481
resolver
genesymbol
Med28
resolver
uniprot
Q3U4G7
resolver
uniprot
Q9CQF2
resolver
uniprot_entry
MED28_MOUSE
resolver
uniprot_sec
Q3U4G7
resolver
uniprot_sec
Q9CQF2
resolver
amino_acid_sequence
MAASLGGMFTGQPPGPPPPPPGLPGQASLLQAAPGAPRPSNSTLVDELESSFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDIARQTECFFLQKRLQLSVQKPDQVIKEDVSELRSELQRKDALVQKHLTKLRHWQQVLEDINVQHKKPADMPQGSLAFLEQASANIPAPLKQT
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
19538
uniprot
proteins
protein_family
Mediator complex subunit 28 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
178
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=May be also cytoplasmic and membrane-associated. {ECO:0000250}.
uniprot
proteins