Tfec
entrez
26296
canonical
uniprot
Q63302
canonical
ensembl
ENSRNOG00000061595
resolver
ensembl
ENSRNOG00055017991
resolver
ensembl
ENSRNOG00060000796
resolver
ensembl
ENSRNOG00065007741
resolver
ensp
ENSRNOP00000073175
resolver
ensp
ENSRNOP00055024537
resolver
ensp
ENSRNOP00060000296
resolver
ensp
ENSRNOP00065008839
resolver
enst
ENSRNOT00000086810
resolver
enst
ENSRNOT00055030484
resolver
enst
ENSRNOT00060000974
resolver
enst
ENSRNOT00065012110
resolver
genesymbol
Tfec
resolver
genesymbol_syn
Tcfec
resolver
uniprot_entry
TFEC_RAT
resolver
amino_acid_sequence
MTLDHRLFSQTLKRAQPLAASCMPLAEHGPRSPDSDAGCAGNPFTNPLALGKEDGVVEWRLSGSILDVYSGEQGISPVNTGLMNASCPSILPMKKEIAETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDIRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLMLRIQELEIQARAHGLPILASLGTADFGTHITKQQTHSEKNSVGCCQQLTPSQGTSPEFYEQAVAFSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISPAVSKASSRSSLSSEDGDEL
uniprot
proteins
function
FUNCTION: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:8336698}.
uniprot
proteins
mass_dalton
35175
uniprot
proteins
protein_family
MiT/TFE family
uniprot
proteins
pubmed
8336698
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
uniprot
proteins