FCGR2A
entrez
2212
canonical
uniprot
P12318
canonical
ensembl
ENSG00000143226
resolver
ensp
ENSP00000271450
resolver
ensp
ENSP00000356949
resolver
ensp
ENSP00000514258
resolver
ensp
ENSP00000684390
resolver
enst
ENST00000699277
resolver
genesymbol
FCGR2A
resolver
genesymbol_syn
CD32
resolver
genesymbol_syn
FCG2
resolver
genesymbol_syn
FCGR2A1
resolver
genesymbol_syn
IGFR2
resolver
hgnc
HGNC:3616
resolver
uniprot
A0A8V8TPS4
resolver
uniprot
Q8WUN1
resolver
uniprot
Q8WW64
resolver
uniprot_entry
A0A8V8TPS4_HUMAN
resolver
uniprot_entry
FCG2A_HUMAN
resolver
uniprot_sec
Q8WUN1
resolver
uniprot_sec
Q8WW64
resolver
amino_acid_sequence
MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDKNIYLTLPPNDHVNSNN
uniprot
proteins
function
FUNCTION: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. {ECO:0000269|PubMed:19011614}.
uniprot
proteins
mass_dalton
35001
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. {ECO:0000269|PubMed:8132624, ECO:0000269|PubMed:8756631}.
uniprot
proteins
pubmed
10331870
uniprot
proteins
pubmed
10397151
uniprot
proteins
pubmed
11397093
uniprot
proteins
pubmed
11711607
uniprot
proteins
pubmed
12690104
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
19011614
uniprot
proteins
pubmed
2526077
uniprot
proteins
pubmed
2529342
uniprot
proteins
pubmed
2824655
uniprot
proteins
pubmed
28566370
uniprot
proteins
pubmed
2965389
uniprot
proteins
pubmed
3402431
uniprot
proteins
pubmed
37421619
uniprot
proteins
pubmed
8132624
uniprot
proteins
pubmed
8327512
uniprot
proteins
pubmed
8636449
uniprot
proteins
pubmed
8756631
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19011614}; Single-pass type I membrane protein {ECO:0000269|PubMed:19011614}.
uniprot
proteins
transmembrane_region
TRANSMEM 218..240; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins