Tsga10
entrez
211484
canonical
uniprot
Q6NY15
canonical
ensembl
ENSMUSG00000060771
resolver
ensp
ENSMUSP00000048859
resolver
ensp
ENSMUSP00000085391
resolver
ensp
ENSMUSP00000110552
resolver
ensp
ENSMUSP00000159265
resolver
ensp
ENSMUSP00000314688
resolver
genesymbol
Tsga10
resolver
uniprot
Q68RJ4
resolver
uniprot
Q8K3V2
resolver
uniprot_entry
TSG10_MOUSE
resolver
uniprot_sec
Q68RJ4
resolver
uniprot_sec
Q8K3V2
resolver
amino_acid_sequence
MMRNRSKSPRRPSPTSRAANCDVELLKSTARDREELKCMLEKYERHLAEIQGNVKVLTSERDKTFLLYEQAQEEIARLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMANMTLMKETITTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGATLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQSTEALIMCEQDISRMRRQLDETNDELGQIARERDILAHENDNLQEQFAKVKQENQALSKKLNDTHNELSDIKQKVQDTNLEVNKLKNILKSEESENRQIMEQLRKANEDAENWENKARQTEAENNTLKLELITAEAEGNRLKEKVDALNREVEQHLNAERSYKSQIATLHKSLVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMMENELDSARSEIELLRSQMTNERISMQNLEALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYNLGPMKPNTKCHSPERAHHRSPDRGLDRSLEENLCYRDF
uniprot
proteins
function
FUNCTION: Plays a role in spermatogenesis (PubMed:14585816). When overexpressed, prevents nuclear localization of HIF1A (PubMed:16777103). {ECO:0000269|PubMed:14585816, ECO:0000269|PubMed:16777103}.
uniprot
proteins
mass_dalton
81262
uniprot
proteins
post_translational_modification
PTM: Processed into N-terminal 27-kDa and C-terminal 55-kDa fragments. {ECO:0000269|PubMed:14585816}.
uniprot
proteins
protein_family
CEP135/TSGA10 family
uniprot
proteins
pubmed
14585816
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16643851
uniprot
proteins
pubmed
16777103
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
697
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Z220}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9BZW7}. Note=In mature spermatozoa, localizes to the centriole and midpiece (By similarity). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (PubMed:16643851, PubMed:16777103). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). {ECO:0000250|UniProtKB:Q9BZW7, ECO:0000250|UniProtKB:Q9Z220, ECO:0000269|PubMed:16643851, ECO:0000269|PubMed:16777103}.
uniprot
proteins