Cox20
entrez
66359
canonical
uniprot
Q9D7J4
canonical
ensembl
ENSMUSG00000026500
resolver
ensp
ENSMUSP00000027781
resolver
enst
ENSMUST00000027781
resolver
genesymbol
Cox20
resolver
genesymbol_syn
Fam36a
resolver
uniprot
Q8BT52
resolver
uniprot_entry
COX20_MOUSE
resolver
uniprot_sec
Q8BT52
resolver
amino_acid_sequence
MAAAPEPHETEKKPFKLLGILDVENTPCARESILYGSLGSIVTGLGHFLVTSRIRRSCDVGVGGFILVTLGCWFHCRYNFAKQRIQERIAREGIKNKILYESTHLDPERKMKTNNSS
uniprot
proteins
function
FUNCTION: Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme. {ECO:0000250|UniProtKB:Q5RI15}.
uniprot
proteins
mass_dalton
13163
uniprot
proteins
protein_family
COX20 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
117
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q5RI15}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 33..50; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 60..76; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins