RBP1
entrez
5947
canonical
uniprot
P09455
canonical
ensembl
ENSG00000114115
resolver
ensp
ENSP00000429166
resolver
ensp
ENSP00000477621
resolver
ensp
ENSP00000482165
resolver
ensp
ENSP00000500931
resolver
enst
ENST00000672186
resolver
genesymbol
RBP1
resolver
genesymbol_syn
CRBP1
resolver
hgnc
HGNC:9919
resolver
uniprot
A0A0A0MQT0
resolver
uniprot
A8K2Q0
resolver
uniprot
B7Z7A0
resolver
uniprot
E7EWV0
resolver
uniprot
F2Z2F2
resolver
uniprot
Q6FGX8
resolver
uniprot_entry
A0A0A0MQT0_HUMAN
resolver
uniprot_entry
RET1_HUMAN
resolver
uniprot_sec
A8K2Q0
resolver
uniprot_sec
B7Z7A0
resolver
uniprot_sec
E7EWV0
resolver
uniprot_sec
F2Z2F2
resolver
uniprot_sec
Q6FGX8
resolver
amino_acid_sequence
MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
uniprot
proteins
function
FUNCTION: Cytoplasmic retinol-binding protein (PubMed:22665496, PubMed:26900151, PubMed:28057518). Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis (PubMed:15632377, PubMed:22665496). {ECO:0000269|PubMed:15632377, ECO:0000269|PubMed:22665496, ECO:0000269|PubMed:26900151, ECO:0000269|PubMed:28057518}.
uniprot
proteins
mass_dalton
15850
uniprot
proteins
mutagenesis
MUTAGEN 22; /note="R->A: No effect on retinol binding. Abolishes interaction with STA6 and the ability to enhance STA6-mediated vitamin A uptake."; /evidence="ECO:0000269|PubMed:28057518"; MUTAGEN 30; /note="L->A: Decreases cellular retinol uptake and impairs retinol storage."; /evidence="ECO:0000269|PubMed:15632377"; MUTAGEN 31; /note="R->A: No effect on retinol binding. Abolishes interaction with STA6 and the ability to enhance STA6-mediated vitamin A uptake."; /evidence="ECO:0000269|PubMed:28057518"; MUTAGEN 32; /note="K->A: No effect on retinol binding. Abolishes interaction with STA6 and the ability to enhance STA6-mediated vitamin A uptake."; /evidence="ECO:0000269|PubMed:28057518"; MUTAGEN 41; /note="K->L: Strongly decreased affinity for retinol. Further decrease in affinity for retinol; when associated with L-109."; /evidence="ECO:0000269|PubMed:28057518"; MUTAGEN 59; /note="R->E: Decreases cellular retinol uptake and impairs retinol storage."; /evidence="ECO:0000269|PubMed:15632377"; MUTAGEN 109; /note="Q->L: Strongly decreased affinity for retinol. Further decrease in for retinol; when associated with L-41."; /evidence="ECO:0000269|PubMed:28057518
uniprot
proteins
protein_family
Calycin superfamily
uniprot
proteins
protein_family
Fatty-acid binding protein (FABP) family
uniprot
proteins
pubmed
11274389
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15632377
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22665496
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
26900151
uniprot
proteins
pubmed
28057518
uniprot
proteins
pubmed
2856408
uniprot
proteins
pubmed
2992469
uniprot
proteins
pubmed
3356192
uniprot
proteins
sequence_length
135
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305|PubMed:22665496}. Lipid droplet {ECO:0000269|PubMed:15632377}.
uniprot
proteins