Rbsn
entrez
78287
canonical
uniprot
Q80Y56
canonical
ensembl
ENSMUSG00000014550
resolver
ensp
ENSMUSP00000014694
resolver
enst
ENSMUST00000014694
resolver
genesymbol
Rbsn
resolver
genesymbol_syn
Zfyve20
resolver
uniprot
Q8K0L6
resolver
uniprot
Q9CTW0
resolver
uniprot_entry
RBNS5_MOUSE
resolver
uniprot_sec
Q8K0L6
resolver
uniprot_sec
Q9CTW0
resolver
amino_acid_sequence
MASLDDPGEVREGFLCPLCLKDLQSFYQLQSHYEEEHLEDRDVKGQIKNLVQKARKAKNKLLKREGDDRVEPGTQGYESFSYGGVDPYMWEPQELGAMRSHLSDFKKHRAARIDHYVVEVNKLIIRLEKLTAFDRTNTETSKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELIGLPLAHKLTSASKDSLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDKLLKREQQMDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYNLEHANDLRVEVQKVYELIDALSKKILTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDLEQKRTVERQAALESRRKLEERQSGLASHTANGDVRSLRGIPPPLRKAEGWLPLSEGQGQSEDPDPLLQQIYNITSFIRQAKAAGRTDEVRTLQENLRQLQDEYDQQQTEKAIELSRKQAEEEELQREQLQMLRKRELEREQEQFLAASLQTRTRVLELREVIPFQLEASRGPHIDLSYSLDQDSSPVQSSTAPDILTPGSALAPMHLWSGPPALGQETLPQSTMSQQSDKASLNPFDEDDLSSPTEGAISPAAVEAFLGPPAAVTKEYNPFEEDAEEEEVAELGAGNPFTDPDSPAPNPFDEDDGPRPASPAAPGNPFEECPSTNPFEVDSDSGMEAEEHIEEELLLQQIDNIKAYIFDAKQCGRMDEVEVLTENLRELKCTLAKQKGAPN
uniprot
proteins
function
FUNCTION: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3). Plays a role in the recycling of transferrin receptor to the plasma membrane (By similarity). {ECO:0000250|UniProtKB:Q9H1K0}.
uniprot
proteins
mass_dalton
88491
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
783
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Early endosome membrane {ECO:0000250|UniProtKB:Q9H1K0}; Lipid-anchor {ECO:0000250}. Note=Enriched in endosomes that are in close proximity to clathrin-enriched regions at the cell surface (By similarity). {ECO:0000250|UniProtKB:Q9H1K0}.
uniprot
proteins