Lrrc34
entrez
499589
canonical
uniprot
Q4V8D9
canonical
ensembl
ENSRNOG00000027935
resolver
ensp
ENSRNOP00000033262
resolver
ensp
ENSRNOP00000109342
resolver
enst
ENSRNOT00000152786
resolver
genesymbol
Lrrc34
resolver
uniprot
A0ABK0LEX2
resolver
uniprot_entry
A0ABK0LEX2_RAT
resolver
uniprot_entry
LRC34_RAT
resolver
amino_acid_sequence
MEKLQDQYSFLCSENIRKTNPLILNILQKLDEEIEKRPKEKITVNIAGNSRLDSGQRITSEDFWLLSKALRNHPCIGGVDVRYNLIGDVGAYYAAKLLQKQPNITYLNLMFNDIGPEGGELIAKALQKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQSVIAFSTVLTQNKAIKGINLNRPILYGEQEESTVHIGHMSKQNHVLVELHMCKHGMKNYGIQQLCNALHSNSTLRYLDVSCNKITRDGMVFLADVLKSNSTLEVLDLSFNRIENAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMNTNLVLSNIYIWGNKFDEDTCVAYSNLIESGRLKPENTDVEPYVVDEHIYLSEVSNGLKRHYYWTPTYGECYVPSSSAGFALVPVGERL
uniprot
proteins
function
FUNCTION: Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. {ECO:0000250|UniProtKB:Q9DAM1}.
uniprot
proteins
mass_dalton
46469
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9DAM1}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9DAM1}. Cytoplasm {ECO:0000250|UniProtKB:Q9DAM1}. Note=As stem cells differentiate, translocates from the nucleolus to the nucleus and then to the cytoplasm. Colocalizes with NPM1 and NCL in the nucleolus. {ECO:0000250|UniProtKB:Q9DAM1}.
uniprot
proteins