Ssx2ip
entrez
308023
canonical
uniprot
Q8CGZ2
canonical
ensembl
ENSRNOG00000015425
resolver
ensembl
ENSRNOG00055025031
resolver
ensembl
ENSRNOG00060000856
resolver
ensembl
ENSRNOG00065012819
resolver
ensp
ENSRNOP00000043877
resolver
ensp
ENSRNOP00000101432
resolver
ensp
ENSRNOP00055035207
resolver
ensp
ENSRNOP00060000365
resolver
ensp
ENSRNOP00065016154
resolver
enst
ENSRNOT00000041186
resolver
enst
ENSRNOT00000144435
resolver
enst
ENSRNOT00055043153
resolver
enst
ENSRNOT00060001060
resolver
enst
ENSRNOT00065020949
resolver
genesymbol
Ssx2ip
resolver
uniprot
A0ABK0L8S8
resolver
uniprot_entry
A0ABK0L8S8_RAT
resolver
uniprot_entry
ADIP_RAT
resolver
amino_acid_sequence
MGDWMTVTDPVLCTENKNLSQYTSETKMSPSSLYSQQVLCSATPLSKNVHGVFSAFCTGENIEQSISYLDQELTTFGFPSLYEESKSKEAKRELSIVALLNCMNELLVLQRKNLLAQESVETQNLKLGSDMDHLQSCYAKLKEQLEASRREMISLQERDRQLQCKNRNLHQLLKNEKEEVQKLQNIIASRATQYNHDVKRKEREYNKLKERLHQLVMNKKDKNIAMDVLNYVGRVDGKRGSWRTDKTEARNEDEMYKILLNDYEYRQKQILLENAELKKVLQQMKKEMISLLSPQKKKPRERAEDSTGTVVISDVEDDAGELSRDGVWSLSCDTVREQLTNSIRKQWRILKSHVEKLDNQASKVHSEGFHEEDVISRQDHEQETEKLELEIERCKEMIKAQQQLLQQQLATACDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWVKQQFLNMTTFDHQNSENVKLFSAFSGSSDPDNLIVHPRPRQKKPHSVANGVPACTSKLAKSLPTSPSDFCPSRSCVSEHSPVSALTVTPEETKPNEVGRESTDQKWSVVSRPSSREGCYGGCSSAYTSSHVERDDLP
uniprot
proteins
function
FUNCTION: Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (PubMed:12446711). Involved in ciliogenesis (By similarity). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (By similarity). {ECO:0000250|UniProtKB:Q8VC66, ECO:0000250|UniProtKB:Q9Y2D8, ECO:0000269|PubMed:12446711}.
uniprot
proteins
mass_dalton
70679
uniprot
proteins
protein_family
ADIP family
uniprot
proteins
pubmed
12446711
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
613
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, adherens junction {ECO:0000269|PubMed:12446711}. Nucleus {ECO:0000250|UniProtKB:Q9Y2D8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000250|UniProtKB:Q9Y2D8}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9Y2D8}. Note=Not found at cell-matrix AJs.
uniprot
proteins