GIGYF1
entrez
64599
canonical
uniprot
O75420
canonical
ensembl
ENSG00000146830
resolver
ensp
ENSP00000275732
resolver
ensp
ENSP00000494292
resolver
ensp
ENSP00000503354
resolver
ensp
ENSP00000563874
resolver
ensp
ENSP00000563875
resolver
ensp
ENSP00000563878
resolver
ensp
ENSP00000563880
resolver
ensp
ENSP00000595415
resolver
ensp
ENSP00000631763
resolver
ensp
ENSP00000631764
resolver
ensp
ENSP00000631766
resolver
enst
ENST00000275732
resolver
enst
ENST00000646601
resolver
enst
ENST00000678049
resolver
enst
ENST00000893815
resolver
enst
ENST00000893816
resolver
enst
ENST00000893819
resolver
enst
ENST00000893821
resolver
enst
ENST00000925356
resolver
enst
ENST00000961704
resolver
enst
ENST00000961705
resolver
enst
ENST00000961707
resolver
genesymbol
GIGYF1
resolver
genesymbol_syn
CDS2
resolver
genesymbol_syn
PERQ1
resolver
hgnc
HGNC:9126
resolver
uniprot
Q6Y7W7
resolver
uniprot
Q8WZ38
resolver
uniprot_entry
GGYF1_HUMAN
resolver
uniprot_sec
Q6Y7W7
resolver
uniprot_sec
Q8WZ38
resolver
amino_acid_sequence
MAAETLNFGPEWLRALSGGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGRGSTRSRGRGRGDSCFYQRSIEEGDGAFGRSPREIQRSQSWDDRGERRFEKSARRDGARCGFEEGGAGPRKEHARSDSENWRSLREEQEEEEEGSWRLGAGPRRDGDRWRSASPDGGPRSAGWREHGERRRKFEFDLRGDRGGCGEEEGRGGGGSSHLRRCRAPEGFEEDKDGLPEWCLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQELDFQGLEEEEEPSEGLEEEGPEAGGKELTPLPPQEEKSSSPSPLPTLGPLWGTNGDGDETAEKEPPAAEDDIRGIQLSPGVGSSAGPPGDLEDDEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSAAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQQFLQLVSSRQLPQCALREKAALGDLTPPPPPPPQQQQQQLTAFLQQLQALKPPRGGDQNLLPTMSRSLSVPDSGRLWDVHTSASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRRQQQQEEQKRRQEEEELFRRKHVRQQELLLKLLQQQQAVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQLEGERQLHKQPPPREPARAQAPNHRVQLGGLGTAPLNQWVSEAGPLWGGPDKSGGGSSGLGLWEDTPKSGGSLVRGLGLKNSRSSPSLSDSYSHLSGRPIRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATGSLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQEAWLSSASLQTAFQANHSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGSSGEIESVDDY
uniprot
proteins
function
FUNCTION: May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity). {ECO:0000250, ECO:0000269|PubMed:12771153}.
uniprot
proteins
mass_dalton
114601
uniprot
proteins
mutagenesis
MUTAGEN 294; /note="W->A: Abolishes interaction with DDX6."; /evidence="ECO:0000269|PubMed:31439631"; MUTAGEN 306; /note="F->A: Abolishes interaction with DDX6; when associated with A-312."; /evidence="ECO:0000269|PubMed:31439631"; MUTAGEN 312; /note="F->A: Abolishes interaction with DDX6; when associated with A-306."; /evidence="ECO:0000269|PubMed:31439631
uniprot
proteins
protein_family
GIGYF family
uniprot
proteins
pubmed
12771153
uniprot
proteins
pubmed
15498874
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
31439631
uniprot
proteins
pubmed
9799793
uniprot
proteins
sequence_length
1035
uniprot
proteins