CXCL1
entrez
2919
canonical
uniprot
P09341
canonical
ensembl
ENSG00000163739
resolver
ensp
ENSP00000379110
resolver
enst
ENST00000395761
resolver
genesymbol
CXCL1
resolver
genesymbol_syn
GRO
resolver
genesymbol_syn
GRO1
resolver
genesymbol_syn
GROA
resolver
genesymbol_syn
MGSA
resolver
genesymbol_syn
SCYB1
resolver
hgnc
HGNC:4602
resolver
uniprot
Q9UCR7
resolver
uniprot_entry
GROA_HUMAN
resolver
uniprot_sec
Q9UCR7
resolver
amino_acid_sequence
MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN
uniprot
proteins
function
FUNCTION: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. {ECO:0000269|PubMed:10095777}.
uniprot
proteins
mass_dalton
11301
uniprot
proteins
post_translational_modification
PTM: N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. {ECO:0000269|PubMed:10095777}.
uniprot
proteins
protein_family
Intercrine alpha (chemokine CxC) family
uniprot
proteins
pubmed
10095777
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1755384
uniprot
proteins
pubmed
2129556
uniprot
proteins
pubmed
2182761
uniprot
proteins
pubmed
2655583
uniprot
proteins
pubmed
2670560
uniprot
proteins
pubmed
2890161
uniprot
proteins
pubmed
2970963
uniprot
proteins
pubmed
7806518
uniprot
proteins
pubmed
8089846
uniprot
proteins
pubmed
8397104
uniprot
proteins
sequence_length
107
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins