Spdya
entrez
192209
canonical
uniprot
Q8R496
canonical
ensembl
ENSRNOG00000004534
resolver
ensembl
ENSRNOG00055019844
resolver
ensembl
ENSRNOG00060012729
resolver
ensembl
ENSRNOG00065021129
resolver
ensp
ENSRNOP00000006073
resolver
ensp
ENSRNOP00000110560
resolver
ensp
ENSRNOP00055027552
resolver
ensp
ENSRNOP00060017082
resolver
ensp
ENSRNOP00065028962
resolver
enst
ENSRNOT00000006073
resolver
enst
ENSRNOT00000141813
resolver
enst
ENSRNOT00055033928
resolver
enst
ENSRNOT00060021615
resolver
enst
ENSRNOT00065035923
resolver
genesymbol
Spdya
resolver
genesymbol_syn
Spdy1
resolver
uniprot
A0ABK0LW84
resolver
uniprot
Q68G34
resolver
uniprot_entry
A0ABK0LW84_RAT
resolver
uniprot_entry
SPDYA_RAT
resolver
uniprot_sec
Q68G34
resolver
amino_acid_sequence
MRHNQMCCETPPTVTVHVKSGSNRSHQTRKPVSLKRPILKDSWQASEKNAHNNKPKRPRGPCLIIQRQEMTAFFKLFDDDLIQDFLWMDCCCKIADKYLLAMTFVYFKRAKFTISEHTRINFFIALYLANTVEEDEEEAKYEIFPWALGKNWRKLFPNFLKLRDQLWDRIDYRAIVSRRCCEEVMAIAPSHYIWQRERSVHHSGAARNYNRDEVHLPRGPSATPVDCSLCGKKGRYVRLGLSSSSSSSSDIVELTGKRSQELHNSLSMDMIGDPSQANTYSQVANDHQSKKENETNFVKKTKSMGWFAESEE
uniprot
proteins
function
FUNCTION: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Interferes with CDKN1B-mediated inhibition of CDK2. Mediates cell survival during the DNA damage process through activation of CDK2. {ECO:0000250|UniProtKB:Q5IBH7, ECO:0000250|UniProtKB:Q5MJ70}.
uniprot
proteins
mass_dalton
36223
uniprot
proteins
protein_family
Speedy/Ringo family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
312
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q5MJ70}.
uniprot
proteins