Dis3l
entrez
363077
canonical
uniprot
Q5U2P0
canonical
ensembl
ENSRNOG00000010537
resolver
ensembl
ENSRNOG00055024442
resolver
ensembl
ENSRNOG00060020141
resolver
ensembl
ENSRNOG00065006417
resolver
ensp
ENSRNOP00000014071
resolver
ensp
ENSRNOP00055034263
resolver
ensp
ENSRNOP00060028651
resolver
ensp
ENSRNOP00065007185
resolver
enst
ENSRNOT00000014071
resolver
enst
ENSRNOT00055042027
resolver
enst
ENSRNOT00060034897
resolver
enst
ENSRNOT00065009883
resolver
genesymbol
Dis3l
resolver
uniprot_entry
DI3L1_RAT
resolver
amino_acid_sequence
MLQKREKVLLLRTFQGRTLRIVREHYLRPSVPCNSPLCPQPATCRNDGKLLSAEVTHYVIPDWKVVQDYLEVLEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCVLFANEFQQHCYLPREKGEAMEKWQTRSIYNSAVWYYHHCEDRMPIVMVTEDEEAIQQYGSETEGVFVISFKNYLDNFWPDLKAAHELCDSIIQSRRERESESQETHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSGLVSDILIHGSKARNRSIHGDVVVVELLPKSEWKGRTAALCENDSEDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAEALQDFRVVVRIDSWETTSVYPNGHFVRVLGRIGDLEGEIATILVENSINVVPFSEAQMCEMPVNTAENPWKVSPKEEQERRDLRSTHLVFSIDPKGCEDVDDALSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPEFKTLEEQNRQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPSDPLVNKLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKVEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDPETEERCVVDGIIYSIRTNGVLVFIPRFGIKGAAYLKNKDGLVISCGPEGSSEWKPGSLQRSQNKIISTTAGGQSVTFHLFDHVTVRISVQPSRCHSDMIRLEIVSNKPYMMPNTELCHQSSLLLKSELVKEVTRSVEEAQLAQEVKGKVIEEEHQEYRQTKGRSLYTLLEEIRDLALLDVSDSYAM
uniprot
proteins
ec_number
3.1.13.1
uniprot
proteins
function
FUNCTION: Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. {ECO:0000250|UniProtKB:Q8TF46}.
uniprot
proteins
mass_dalton
120759
uniprot
proteins
protein_family
RNR ribonuclease family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
1054
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8TF46}.
uniprot
proteins