SAMM50
entrez
25813
canonical
uniprot
Q9Y512
canonical
ensembl
ENSG00000100347
resolver
ensp
ENSP00000345445
resolver
enst
ENST00000350028
resolver
genesymbol
SAMM50
resolver
genesymbol_syn
SAM50
resolver
hgnc
HGNC:24276
resolver
uniprot
Q53HC4
resolver
uniprot
Q56VW7
resolver
uniprot
Q969Y9
resolver
uniprot
Q96I46
resolver
uniprot
Q9NW85
resolver
uniprot
Q9UQM9
resolver
uniprot_entry
SAM50_HUMAN
resolver
uniprot_sec
Q53HC4
resolver
uniprot_sec
Q56VW7
resolver
uniprot_sec
Q969Y9
resolver
uniprot_sec
Q96I46
resolver
uniprot_sec
Q9NW85
resolver
uniprot_sec
Q9UQM9
resolver
amino_acid_sequence
MGTVHARSLEPLPSSGPDFGGLGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLGRTKDDIIICEIGDVFKAKNLIEVMRKSHEAREKLLRLGIFRQVDVLIDTCQGDDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYGTKETSYGLSFFKPRPGNFERNFSVNLYKVTGQFPWSSLRETDRGMSAEYSFPIWKTSHTVKWEGVWRELGCLSRTASFAVRKESGHSLKSSLSHAMVIDSRNSSILPRRGALLKVNQELAGYTGGDVSFIKEDFELQLNKQLIFDSVFSASFWGGMLVPIGDKPSSIADRFYLGGPTSIRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGIVLRLGNIARLELNYCVPMGVQTGDRICDGVQFGAGIRFL
uniprot
proteins
function
FUNCTION: Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes (PubMed:22252321, PubMed:25781180). Required for the assembly of TOMM40 into the TOM complex (PubMed:15644312). {ECO:0000269|PubMed:15644312, ECO:0000269|PubMed:22252321, ECO:0000269|PubMed:25781180}.
uniprot
proteins
mass_dalton
51976
uniprot
proteins
protein_family
SAM50/omp85 family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15644312
uniprot
proteins
pubmed
21081504
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22114354
uniprot
proteins
pubmed
22252321
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25781180
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
25997101
uniprot
proteins
pubmed
28567444
uniprot
proteins
pubmed
31644573
uniprot
proteins
pubmed
35025629
uniprot
proteins
sequence_length
469
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000269|PubMed:15644312}; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q6AXV4}. Mitochondrion {ECO:0000269|PubMed:25781180}.
uniprot
proteins