Gpaa1
entrez
14731
canonical
uniprot
Q9WTK3
canonical
ensembl
ENSMUSG00000022561
resolver
ensp
ENSMUSP00000023221
resolver
enst
ENSMUST00000023221
resolver
genesymbol
Gpaa1
resolver
genesymbol_syn
Gaa1
resolver
uniprot
Q3TNU9
resolver
uniprot
Q9R1U8
resolver
uniprot_entry
GPAA1_MOUSE
resolver
uniprot_sec
Q3TNU9
resolver
uniprot_sec
Q9R1U8
resolver
amino_acid_sequence
MGLLSDPVRRRALARIVLRLNTPLCVLSYVAGIAWFLALAFPPLTQRTYMSENAMGSTMVEEQFVGGDRARSFARDFAAHRKKPGALPVAWLERSMRSVGLEVYTQSFSRKLPFPDETHERYMVSGTNVYGILRAPRSASTESLVLTVPCGPDATNSQAVGLLLALAAHFRGQIYWAKDIIFLVTDHDLLGTEAWLEAYHDINVTGIQSSPLQGRAGAIQAAVALELSSDVVTSLDVTVEGLNGQLPNLDLLNLFQTFCQKGGLLCTLQGKLQPQDWTSLEGPLQGLQTLLLMVLRQASGRPHGPHGLFLRYGVEALTLRGINSFRQYKYDLATVGKALEGMFRKLNHLLERLHQSFFFYLLPALSRFVSIGLYMPATGFLLLVLGLKALELWMQLHQAGVNPEEAGKAPSPGTPLLPTQGVGLASLTAPLLISQAMGLALYFLPVLGQHLATQHFPVAEAEAVVLTLLAIYVAGLALPHNTHRVVNSQVPDRGWMALKLVALIYLALQLGCIALLNFSLGFLLAATMVPAAALAKPHGPRTLYAALLVVTSPAVTLFGSLFLWRELLEVPLSLAEGWQLFLTALAQGVLEHYTYGALLFPILALGLYPCWLLFWNVLFWK
uniprot
proteins
function
FUNCTION: Component of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis (PubMed:10793132, PubMed:10898732). Binds GPI-anchor (By similarity). {ECO:0000250|UniProtKB:O43292, ECO:0000269|PubMed:10793132, ECO:0000269|PubMed:10898732}.
uniprot
proteins
mass_dalton
67949
uniprot
proteins
pathway_participation
PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis. {ECO:0000269|PubMed:10793132, ECO:0000269|PubMed:10898732}.
uniprot
proteins
pubmed
10393431
uniprot
proteins
pubmed
10793132
uniprot
proteins
pubmed
10898732
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
621
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O43292}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O43292}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..41; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292"; TRANSMEM 371..393; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292"; TRANSMEM 426..450; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292"; TRANSMEM 463..483; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292"; TRANSMEM 496..519; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292"; TRANSMEM 520..536; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292"; TRANSMEM 541..563; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292"; TRANSMEM 598..619; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O43292
uniprot
proteins