A2ANX9
uniprot
A2ANX9
canonical
amino_acid_sequence
MESGGGSLGLHTSDARMAHTMIMQDFVAGMAGTAHIDGDHIVVSVPEAVLVSDVVTDDGITLDHGLAAEVVHGPDIITETDVVTEGVIVPEAVLEADVAIEEDLEEDDGDHILTSELITETVRVPEQVFVADLVSGPDGHLEHVVQDCVSGVDSPTMVSEEVLVTNSDTETVIQAGGGVPGSTVTIKTEEDDDDDVKSTSEDYLMISLDDVGEKLEHMGNTPLKIASDGSQEDVKEDAFGSEVIKVYIFKAEAEDDVEIGGTEIVTESEYSSGHSVAGVLDQSRMQREKMVYMAVKDSSQEQDDIRDERRVSRRYEECQAPGNTFDSALENRNTTAAQYLQICDSMNTNKVLKQKIKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSRGFLKRHMKNHPDHLMRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKSFPHVCVECGKGFRHPSELKKHMRTHTGEKPYQCQYCAFRCADQSNLKTHIKSKHGSNLPYKCEHCPQAFGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHTGRKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCKKGFRRPSEKKQHIMRHHKETLM
uniprot
proteins
function
FUNCTION: Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activated expression of genes involved in neuron development, such as KDM5C. May compete with transcription factor ARX for activation of expression of KDM5C. {ECO:0000250|UniProtKB:Q9Y462}.
uniprot
proteins
mass_dalton
86415
uniprot
proteins
protein_family
Krueppel C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
761
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins