Miga2
entrez
108958
canonical
uniprot
Q8BK03
canonical
ensembl
ENSMUSG00000026858
resolver
ensp
ENSMUSP00000077127
resolver
ensp
ENSMUSP00000097787
resolver
ensp
ENSMUSP00000228098
resolver
genesymbol
Miga2
resolver
genesymbol_syn
Fam73b
resolver
uniprot
A6PX05
resolver
uniprot
Q3U4J7
resolver
uniprot
Q3UST7
resolver
uniprot_entry
MIGA2_MOUSE
resolver
uniprot_sec
A6PX05
resolver
uniprot_sec
Q3U4J7
resolver
uniprot_sec
Q3UST7
resolver
amino_acid_sequence
MAFRRTEGMSMIQALAMTVAEIPVFLYTTFGQSAFSQLRLTPGLRKVLFATALGTVALALAAHQLKRRRRKKKQVGPEMGGEQLGTVPMPILMARKVPSVKKGCSSRRVQSPSSKSNDTLSGISSIEPSKHSGSSHSLASMVVVNSSSPTAACSGSWEARGMEESVPTTDGSAESLYVQGMELFEEALQKWEQALSVGQRGDGGSTPTPGDSLQNPDTASEALSEPESQRREFAEKLESLLHRAYHLQEEFGSTFPSDSMLLDLERTLMLPLTEGSLRLRADDEDSLTSEDSFFSATEIFESLQIGEYPLPLSRPAAAYEEALQLVKEGRVPCRTLRTELLGCYSDQDFLAKLHCVRQAFEGLLEERSNQIFFGEVGRQMVTGLMTKAEKSPKGFLESYEEMLSYALRPETWATTRLELEGRGVACMSFFDIVLDFILMDAFEDLENPPSSVLAVLRNRWLSDSFKETALATACWSVLKAKRRLLMVPDGFISHFYSVSEHVSPVLAFGFLGPKPQLSEVCAFFKHQIVQYLRDMFDLDNVRYTSVPALAEDILQLSRRRSEILLGYLGAPVASSIGLNGPLPRENGPLEELQ
uniprot
proteins
function
FUNCTION: Regulator of mitochondrial fusion (PubMed:26711011). Acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD (By similarity). {ECO:0000250|UniProtKB:Q7L4E1, ECO:0000269|PubMed:26711011}.
uniprot
proteins
mass_dalton
65548
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Ser-295 of the FFAT motif activates interaction with MOSPD2. {ECO:0000250|UniProtKB:Q7L4E1}.
uniprot
proteins
protein_family
Mitoguardin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26711011
uniprot
proteins
pubmed
26716412
uniprot
proteins
sequence_length
593
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q7L4E1}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 42..62; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins