MAP4K5
entrez
11183
canonical
uniprot
Q9Y4K4
canonical
ensembl
ENSG00000012983
resolver
ensp
ENSP00000013125
resolver
ensp
ENSP00000507200
resolver
ensp
ENSP00000542413
resolver
ensp
ENSP00000607410
resolver
ensp
ENSP00000607411
resolver
enst
ENST00000013125
resolver
enst
ENST00000682126
resolver
genesymbol
MAP4K5
resolver
hgnc
HGNC:6867
resolver
uniprot
A0A0A0MQR1
resolver
uniprot
A0A804HIS2
resolver
uniprot
B3KWC4
resolver
uniprot
Q8IYF6
resolver
uniprot_entry
B3KWC4_HUMAN
resolver
uniprot_entry
M4K5_HUMAN
resolver
uniprot_sec
A0A0A0MQR1
resolver
uniprot_sec
A0A804HIS2
resolver
uniprot_sec
Q8IYF6
resolver
amino_acid_sequence
MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNHAHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPKPAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILAGHENSY
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. {ECO:0000269|PubMed:9038372}.
uniprot
proteins
mass_dalton
95054
uniprot
proteins
mutagenesis
MUTAGEN 49; /note="K->R: Loss of kinase activity and ability to activate JNK family."; /evidence="ECO:0000269|PubMed:9038372
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
STE Ser/Thr protein kinase family
uniprot
proteins
protein_family
STE20 subfamily
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9038372
uniprot
proteins
pubmed
9788432
uniprot
proteins
sequence_length
846
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:9038372}.
uniprot
proteins