MACC1
entrez
346389
canonical
uniprot
Q6ZN28
canonical
ensembl
ENSG00000183742
resolver
ensp
ENSP00000328410
resolver
ensp
ENSP00000383185
resolver
ensp
ENSP00000466864
resolver
ensp
ENSP00000580193
resolver
ensp
ENSP00000580194
resolver
ensp
ENSP00000580195
resolver
ensp
ENSP00000580196
resolver
ensp
ENSP00000609118
resolver
enst
ENST00000332878
resolver
enst
ENST00000400331
resolver
enst
ENST00000589011
resolver
enst
ENST00000910134
resolver
enst
ENST00000910135
resolver
enst
ENST00000910136
resolver
enst
ENST00000910137
resolver
enst
ENST00000939059
resolver
genesymbol
MACC1
resolver
hgnc
HGNC:30215
resolver
uniprot
A8MUS5
resolver
uniprot
B2RNR9
resolver
uniprot
Q6ZQN8
resolver
uniprot
Q7Z5A5
resolver
uniprot_entry
MACC1_HUMAN
resolver
uniprot_sec
A8MUS5
resolver
uniprot_sec
B2RNR9
resolver
uniprot_sec
Q6ZQN8
resolver
uniprot_sec
Q7Z5A5
resolver
amino_acid_sequence
MLITERKHFRSGRIAQSMSEANLIDMEAGKLSKSCNITECQDPDLLHNWPDAFTLRGNNASKVANPFWNQLSASNPFLDDITQLRNNRKRNNISILKEDPFLFCREIENGNSFDSSGDELDVHQLLRQTSSRNSGRSKSVSELLDILDDTAHAHQSIHNSDQILLHDLEWLKNDREAYKMAWLSQRQLARSCLDLNTISQSPGWAQTQLAEVTIACKVNHQGGSVQLPESDITVHVPQGHVAVGEFQEVSLRAFLDPPHMLNHDLSCTVSPLLEIMLGNLNTMEALLLEMKIGAEVRKDPFSQVMTEMVCLHSLGKEGPFKVLSNCYIYKDTIQVKLIDLSQVMYLVVAAQAKALPSPAATIWDYIHKTTSIGIYGPKYIHPSFTVVLTVCGHNYMPGQLTISDIKKGGKNISPVVFQLWGKQSFLLDKPQDLSISIFSCDPDFEVKTEGERKEIKQKQLEAGEVVHQQFLFSLVEHREMHLFDFCVQVEPPNGEPVAQFSITTPDPTPNLKRLSNLPGYLQKKEEIKSAPLSPKILVKYPTFQDKTLNFSNYGVTLKAVLRQSKIDYFLEYFKGDTIALLGEGKVKAIGQSKVKEWYVGVLRGKIGLVHCKNVKVISKEQVMFMSDSVFTTRNLLEQIVLPLKKLTYIYSVVLTLVSEKVYDWKVLADVLGYSHLSLEDFDQIQADKESEKVSYVIKKLKEDCHTERNTRKFLYELIVALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGNTGDVAVEMMWKPAYDFLYTWSAHYGNNYRDVLQDLQSALDRMKNPVTKHWRELTGVLILVNSLEVLRVTAFSTSEEV
uniprot
proteins
function
FUNCTION: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. {ECO:0000269|PubMed:19098908}.
uniprot
proteins
mass_dalton
96639
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19098908
uniprot
proteins
pubmed
19807924
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
852
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19098908}. Nucleus {ECO:0000269|PubMed:19098908}. Note=Mainly found in the cytoplasm in non-metastasizing tumors.
uniprot
proteins