Spcs2
entrez
66624
canonical
uniprot
Q9CYN2
canonical
ensembl
ENSMUSG00000035227
resolver
ensp
ENSMUSP00000041152
resolver
ensp
ENSMUSP00000146514
resolver
enst
ENSMUST00000036274
resolver
enst
ENSMUST00000207063
resolver
genesymbol
Spcs2
resolver
genesymbol_syn
Spc25
resolver
uniprot
A0A140LHR3
resolver
uniprot
Q3THR2
resolver
uniprot
Q80X74
resolver
uniprot
Q921V8
resolver
uniprot
Q9CXK1
resolver
uniprot_entry
A0A140LHR3_MOUSE
resolver
uniprot_entry
SPCS2_MOUSE
resolver
uniprot_sec
Q3THR2
resolver
uniprot_sec
Q80X74
resolver
uniprot_sec
Q921V8
resolver
uniprot_sec
Q9CXK1
resolver
amino_acid_sequence
MAASASQGGRSGGGGGSSGAGGGPSCGTSSSRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLATERKIK
uniprot
proteins
function
FUNCTION: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity). {ECO:0000250|UniProtKB:Q04969, ECO:0000250|UniProtKB:Q15005}.
uniprot
proteins
mass_dalton
24978
uniprot
proteins
protein_family
SPCS2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
226
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q28250}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q28250}.
uniprot
proteins
transmembrane_region
TRANSMEM 87..107; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 112..132; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins