Foxa3
entrez
15377
canonical
uniprot
P35584
canonical
ensembl
ENSMUSG00000040891
resolver
ensp
ENSMUSP00000043173
resolver
enst
ENSMUST00000036018
resolver
genesymbol
Foxa3
resolver
genesymbol_syn
Hnf3g
resolver
genesymbol_syn
Tcf-3g
resolver
genesymbol_syn
Tcf3g
resolver
uniprot_entry
FOXA3_MOUSE
resolver
amino_acid_sequence
MLGSVKMEAHDLAEWSYYPEAGEVYSPVNPVPTMAPLNSYMTLNPLSSPYPPGGLQASPLPTGPLAPPAPTAPLGPTFPSLGTGGSTGGSASGYVAPGPGLVHGKEMAKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAKKGNSATSASRNGTAGSATSATTTAATAVTSPAQPQPTPSEPEAQSGDDVGGLDCASPPSSTPYFSGLELPGELKLDAPYNFNHPFSINNLMSEQTSTPSKLDVGFGGYGAESGEPGVYYQSLYSRSLLNAS
uniprot
proteins
function
FUNCTION: Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; activates GLUT2 transcription. Involved in regulation of neuronal-specific transcription. Involved in regulation of spermatogenesis; required for the maintenance of the testicular germ cell population and male fertility. {ECO:0000250, ECO:0000269|PubMed:11546810, ECO:0000269|PubMed:17488644, ECO:0000269|PubMed:9632808}.
uniprot
proteins
mass_dalton
37601
uniprot
proteins
pubmed
11546810
uniprot
proteins
pubmed
17488644
uniprot
proteins
pubmed
8034310
uniprot
proteins
pubmed
9632808
uniprot
proteins
sequence_length
353
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins