CFAP20
entrez
29105
canonical
uniprot
Q9Y6A4
canonical
ensembl
ENSG00000070761
resolver
ensp
ENSP00000262498
resolver
enst
ENST00000262498
resolver
genesymbol
CFAP20
resolver
genesymbol_syn
BUG22
resolver
genesymbol_syn
C16orf80
resolver
genesymbol_syn
GTL3
resolver
hgnc
HGNC:29523
resolver
uniprot_entry
CFA20_HUMAN
resolver
amino_acid_sequence
MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLLDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ
uniprot
proteins
function
FUNCTION: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (PubMed:24414207). Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). Involved in the regulation of the size and morphology of cilia (PubMed:24414207). Required for axonemal microtubules polyglutamylation (PubMed:24414207). {ECO:0000269|PubMed:24414207, ECO:0000269|PubMed:36191189}.
uniprot
proteins
mass_dalton
22774
uniprot
proteins
protein_family
CFAP20 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
20118210
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24414207
uniprot
proteins
pubmed
36191189
uniprot
proteins
sequence_length
193
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24414207}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:24414207}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:24414207}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:24414207, ECO:0000269|PubMed:36191189}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q8BTU1}.
uniprot
proteins