Mmp9
entrez
17395
canonical
uniprot
P41245
canonical
ensembl
ENSMUSG00000017737
resolver
ensp
ENSMUSP00000017881
resolver
enst
ENSMUST00000017881
resolver
genesymbol
Mmp9
resolver
genesymbol_syn
Clg4b
resolver
uniprot
Q06788
resolver
uniprot
Q80XI8
resolver
uniprot
Q9DC02
resolver
uniprot_entry
MMP9_MOUSE
resolver
uniprot_sec
Q06788
resolver
uniprot_sec
Q80XI8
resolver
uniprot_sec
Q9DC02
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by histatin-3 1/24 (histatin-5). Inhibited by ECM1. {ECO:0000250|UniProtKB:P14780}.
uniprot
proteins
amino_acid_sequence
MSPWQPLLLALLAFGCSSAAPYQRQPTFVVFPKDLKTSNLTDTQLAEAYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSQTLKAIRTPRCGVPDVGRFQTFKGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFAVWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDDDELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDGKFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLYGFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRGSKPDPRPPATTTTEPQPTAPPTMCPTIPPTAYPTVGPTVGPTGAPSPGPTSSPSPGPTGAPSPGPTAPPTAGSSEASTESLSPADNPCNVDVFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDPQTKRVFFFSGRQMWVYTGKTVLGPRSLDKLGLGPEVTHVSGLLPRRLGKALLFSKGRVWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQDKAYFCHGKFFWRVSFQNEVNKVDHEVNQVDDVGYVTYDLLQCP
uniprot
proteins
ec_number
3.4.24.35
uniprot
proteins
function
FUNCTION: Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (By similarity). Could play a role in bone osteoclastic resorption (PubMed:8132709). Cleaves KiSS1 at a Gly-|-Leu bond (By similarity). Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed:23142597, PubMed:32883094). Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide (By similarity). {ECO:0000250|UniProtKB:P14780, ECO:0000269|PubMed:23142597, ECO:0000269|PubMed:32883094, ECO:0000269|PubMed:8132709}.
uniprot
proteins
mass_dalton
80535
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:P14780}.
uniprot
proteins
protein_family
Peptidase M10A family
uniprot
proteins
pubmed
11500442
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19893577
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23142597
uniprot
proteins
pubmed
32883094
uniprot
proteins
pubmed
8132709
uniprot
proteins
pubmed
8219207
uniprot
proteins
pubmed
8243459
uniprot
proteins
pubmed
8382489
uniprot
proteins
sequence_length
730
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P14780}.
uniprot
proteins