P2ry4
entrez
57385
canonical
uniprot
Q9JJS7
canonical
ensembl
ENSMUSG00000044359
resolver
ensp
ENSMUSP00000055869
resolver
enst
ENSMUST00000053373
resolver
genesymbol
P2ry4
resolver
genesymbol_syn
P2y4r
resolver
uniprot
Q0VBT7
resolver
uniprot_entry
P2RY4_MOUSE
resolver
uniprot_entry
Q0VBT7_MOUSE
resolver
amino_acid_sequence
MTSADSLLFTSLGPSPSSGDGDCKFNEEFKFILLPLSYAVVFVLGLALNAPTLWLFLFRLRPWDATATYMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGFCKFVRFLFYWNLYCSVLFLTCISVHRYMGICHPLRAIRWGRPRFAGLLCLGVWLVVAGCLVPNLFFVTTNANGTTILCHDTTLPEEFDHYVYFSSTIMVLLFGFPFLITLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLNAECRVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRNQLQQLCRGSTPKRRTTASSLALVTLHEESISRWADIHQDSIFPAYEGDRL
uniprot
proteins
function
FUNCTION: Receptor for ATP and UTP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system.
uniprot
proteins
mass_dalton
41034
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Ser-329 and Ser-330 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium-activated kinases (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11290369
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
361
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 31..58; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 69..91; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 109..127; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 150..170; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 193..218; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 243..265; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 284..305; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins