RPS6KC1
entrez
26750
canonical
uniprot
Q96S38
canonical
ensembl
ENSG00000136643
resolver
ensp
ENSP00000355926
resolver
ensp
ENSP00000355927
resolver
ensp
ENSP00000439282
resolver
ensp
ENSP00000442306
resolver
ensp
ENSP00000483873
resolver
ensp
ENSP00000484471
resolver
ensp
ENSP00000652701
resolver
ensp
ENSP00000652704
resolver
ensp
ENSP00000706163
resolver
ensp
ENSP00000706167
resolver
ensp
ENSP00000706177
resolver
enst
ENST00000543354
resolver
enst
ENST00000543470
resolver
enst
ENST00000614059
resolver
enst
ENST00000615329
resolver
genesymbol
RPS6KC1
resolver
genesymbol_syn
RPK118
resolver
hgnc
HGNC:10439
resolver
uniprot
A0A087X1U5
resolver
uniprot
B1APS8
resolver
uniprot
B3KVM4
resolver
uniprot
D3DTA4
resolver
uniprot
F5H7T0
resolver
uniprot
F6RJM5
resolver
uniprot
Q8TDD3
resolver
uniprot
Q9NSF4
resolver
uniprot
Q9UL66
resolver
uniprot_entry
A0A087X1U5_HUMAN
resolver
uniprot_entry
F5H7T0_HUMAN
resolver
uniprot_entry
F6RJM5_HUMAN
resolver
uniprot_entry
KS6C1_HUMAN
resolver
uniprot_sec
B1APS8
resolver
uniprot_sec
B3KVM4
resolver
uniprot_sec
D3DTA4
resolver
uniprot_sec
Q8TDD3
resolver
uniprot_sec
Q9NSF4
resolver
uniprot_sec
Q9UL66
resolver
amino_acid_sequence
MTSYRERSADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKNLFRHSELFPPFAKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDFFKGGIINDSSELIGPAEAHSDSLIDTFPECSTEGFSSDSDLVSLTVDVDSLAELDDGMASNQNSPIRTFGLNLSSDSSALGAVASDSEQSKTEEERESRSLFPGSLKPKLGKRDYLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAESISSLYGKPQLDDVSQPPGSLSSRPLWNLRSPAEELKAFRVLGVIDKVLLVMDTRTEQTFILKGLRKSSEYSRNRKTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGKLWSYISKFLNRSPEESFDIKEVKKPTLAKVHLQQPTSSPQDSSSFESRGSDGGSMLKALPLKSSLTPSSQDDSNQEDDGQDSSPKWPDSGSSSEEECTTSYLTLCNEYGQEKIEPGSLNEEPFMKTEGNGVDTKAIKSFPAHLAADSDSPSTQLRAHELKFFPNDDPEAVSSPRTSDSLSRSKNSPMEFFRIDSKDSASELLGLDFGEKLYSLKSEPLKPFFTLPDGDSASRSFNTSESKVEFKAQDTISRGSDDSVPVISFKDAAFDDVSGTDEGRPDLLVNLPGELESTREAAAMGPTKFTQTNIGIIENKLLEAPDVLCLRLSTEQCQAHEEKGIEELSDPSGPKSYSITEKHYAQEDPRMLFVAAVDHSSSGDMSLLPSSDPKFQGLGVVESAVTANNTEESLFRICSPLSGANEYIASTDTLKTEEVLLFTDQTDDLAKEEPTSLFQRDSETKGESGLVLEGDKEIHQIFEDLDKKLALASRFYIPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPLERLGAGVAGVEDIKSHPFFTPVDWAELMR
uniprot
proteins
disease_involvement
DISEASE: Neurodevelopmental disorder with spasticity, thin corpus callosum, and decreased brain white matter (NEDSCW) [MIM:621460]: An autosomal recessive disorder characterized by global developmental delay, impaired intellectual development and progressive spasticity of the lower limbs with hyperreflexia. Brain imaging shows thin corpus callosum and reduced white matter volume. {ECO:0000269|PubMed:41130203}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed:12077123). Plays a role in the recruitment of PRDX3 to early endosomes (PubMed:15750338). {ECO:0000269|PubMed:12077123, ECO:0000269|PubMed:15750338}.
uniprot
proteins
mass_dalton
118682
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
S6 kinase subfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
10552933
uniprot
proteins
pubmed
12077123
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15750338
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
41130203
uniprot
proteins
sequence_length
1066
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12077123, ECO:0000269|PubMed:15750338}. Membrane {ECO:0000269|PubMed:12077123}. Early endosome {ECO:0000269|PubMed:15750338}.
uniprot
proteins