Tnfrsf1b
entrez
21938
canonical
uniprot
P25119
canonical
ensembl
ENSMUSG00000028599
resolver
ensp
ENSMUSP00000030336
resolver
enst
ENSMUST00000030336
resolver
genesymbol
Tnfrsf1b
resolver
genesymbol_syn
Tnfr-2
resolver
genesymbol_syn
Tnfr2
resolver
uniprot
O88734
resolver
uniprot
P97893
resolver
uniprot
Q545P4
resolver
uniprot_entry
Q545P4_MOUSE
resolver
uniprot_entry
TNR1B_MOUSE
resolver
uniprot_sec
O88734
resolver
uniprot_sec
P97893
resolver
amino_acid_sequence
MAPAALWVALVFELQLWATGHTVPAQVVLTPYKPEPGYECQISQEYYDRKAQMCCAKCPPGQYVKHFCNKTSDTVCADCEASMYTQVWNQFRTCLSCSSSCTTDQVEIRACTKQQNRVCACEAGRYCALKTHSGSCRQCMRLSKCGPGFGVASSRAPNGNVLCKACAPGTFSDTTSSTDVCRPHRICSILAIPGNASTDAVCAPESPTLSAIPRTLYVSQPEPTRSQPLDQEPGPSQTPSILTSLGSTPIIEQSTKGGISLPIGLIVGVTSLGLLMLGLVNCIILVQRKKKPSCLQRDAKVPHVPDEKSQDAVGLEQQHLLTTAPSSSSSSLESSASAGDRRAPPGGHPQARVMAEAQGFQEARASSRISDSSHGSHGTHVNVTCIVNVCSSSDHSSQCSSQASATVGDPDAKPSASPKDEQVPFSQEECPSQSPCETTETLQSHEKPLPLGVPDMGMKPSQAGWFDQIAVKVA
uniprot
proteins
function
FUNCTION: Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
50320
uniprot
proteins
pubmed
1645445
uniprot
proteins
pubmed
1849278
uniprot
proteins
pubmed
9740674
uniprot
proteins
sequence_length
474
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 259..288; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins