AFF3
entrez
3899
canonical
uniprot
P51826
canonical
ensembl
ENSG00000144218
resolver
ensp
ENSP00000317421
resolver
ensp
ENSP00000386834
resolver
ensp
ENSP00000387207
resolver
ensp
ENSP00000500419
resolver
genesymbol
AFF3
resolver
genesymbol_syn
LAF4
resolver
hgnc
HGNC:6473
resolver
uniprot
B7ZM46
resolver
uniprot
B9EGL9
resolver
uniprot
D3DVI6
resolver
uniprot
Q53RD6
resolver
uniprot
Q53S47
resolver
uniprot
Q53SI6
resolver
uniprot
Q53TB9
resolver
uniprot
Q59F27
resolver
uniprot
Q8IWJ5
resolver
uniprot
Q8NAP7
resolver
uniprot_entry
AFF3_HUMAN
resolver
uniprot_entry
Q8NAP7_HUMAN
resolver
uniprot_sec
B7ZM46
resolver
uniprot_sec
B9EGL9
resolver
uniprot_sec
D3DVI6
resolver
uniprot_sec
Q53RD6
resolver
uniprot_sec
Q53S47
resolver
uniprot_sec
Q53SI6
resolver
uniprot_sec
Q53TB9
resolver
uniprot_sec
Q59F27
resolver
uniprot_sec
Q8IWJ5
resolver
amino_acid_sequence
MDSFDLALLQEWDLESLCVYEPDRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAAVPVQQSKRGTMGWQKAGHPPSDGQQRATQQGSLRTLLGDGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSSGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSSETSVHCTSYRGVPASKPEPARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPPAVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLS
uniprot
proteins
disease_involvement
DISEASE: KINSSHIP syndrome (KINS) [MIM:619297]: An autosomal dominant disease characterized by developmental delay, impaired intellectual development, seizures, short stature, mesomelic dysplasia, dysmorphic facial features, horseshoe or hypoplastic kidney, and failure to thrive. {ECO:0000269|PubMed:31388108, ECO:0000269|PubMed:33961779}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double-stranded DNA.
uniprot
proteins
mass_dalton
133503
uniprot
proteins
protein_family
AF4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
28397838
uniprot
proteins
pubmed
31388108
uniprot
proteins
pubmed
33961779
uniprot
proteins
pubmed
8555498
uniprot
proteins
sequence_length
1226
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins