Cyct
entrez
25310
canonical
uniprot
P10715
canonical
ensembl
ENSRNOG00000077437
resolver
ensembl
ENSRNOG00055020923
resolver
ensembl
ENSRNOG00060015111
resolver
ensembl
ENSRNOG00065017280
resolver
ensp
ENSRNOP00000008371
resolver
ensp
ENSRNOP00055028967
resolver
ensp
ENSRNOP00060020727
resolver
ensp
ENSRNOP00065022790
resolver
enst
ENSRNOT00000008371
resolver
enst
ENSRNOT00055035706
resolver
enst
ENSRNOT00060025912
resolver
enst
ENSRNOT00065028804
resolver
genesymbol
Cyct
resolver
uniprot_entry
CYC2_RAT
resolver
amino_acid_sequence
MGDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKMIFAGIKKKSEREDLIQYLKEATSS
uniprot
proteins
function
FUNCTION: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; FUNCTION: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11743
uniprot
proteins
post_translational_modification
PTM: Binds 1 heme c group covalently per subunit.; PTM: Phosphorylation at Tyr-49 and Tyr-98 both reduce by half the turnover in the reaction with cytochrome c oxidase, down-regulating mitochondrial respiration. {ECO:0000250}.
uniprot
proteins
protein_family
Cytochrome c family
uniprot
proteins
pubmed
2834389
uniprot
proteins
sequence_length
105
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
uniprot
proteins