P3H4
entrez
10609
canonical
uniprot
Q92791
canonical
ensembl
ENSG00000141696
resolver
ensp
ENSP00000347649
resolver
ensp
ENSP00000377505
resolver
ensp
ENSP00000561225
resolver
ensp
ENSP00000671438
resolver
enst
ENST00000355468
resolver
enst
ENST00000393928
resolver
genesymbol
P3H4
resolver
genesymbol_syn
LEPREL4
resolver
genesymbol_syn
NOL55
resolver
genesymbol_syn
SC65
resolver
hgnc
HGNC:16946
resolver
uniprot
Q53GI6
resolver
uniprot
Q9H4F6
resolver
uniprot_entry
SC65_HUMAN
resolver
uniprot_sec
Q53GI6
resolver
uniprot_sec
Q9H4F6
resolver
amino_acid_sequence
MARVAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPAAKPDPDGGRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPPRQLLRDFQSRLPYQYLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALSEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAMLYHNQTAELRELLEFTHMYLQSDDEMELEETEPPLEPEDALSDAEFEGEGDYEEGMYADWWQEPDAKGDEAEAEPEPELA
uniprot
proteins
function
FUNCTION: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. {ECO:0000250|UniProtKB:Q8K2B0}.
uniprot
proteins
mass_dalton
50381
uniprot
proteins
protein_family
Leprecan family
uniprot
proteins
pubmed
10952778
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23959653
uniprot
proteins
pubmed
8862517
uniprot
proteins
sequence_length
437
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:23959653}.
uniprot
proteins