Nol12
entrez
362955
canonical
uniprot
Q5D1Z3
canonical
ensembl
ENSRNOG00000010209
resolver
ensembl
ENSRNOG00055029174
resolver
ensembl
ENSRNOG00060023113
resolver
ensembl
ENSRNOG00065032228
resolver
ensp
ENSRNOP00000013764
resolver
ensp
ENSRNOP00055041627
resolver
ensp
ENSRNOP00060033030
resolver
ensp
ENSRNOP00065045642
resolver
enst
ENSRNOT00055050546
resolver
enst
ENSRNOT00060040002
resolver
enst
ENSRNOT00065055475
resolver
genesymbol
Nol12
resolver
genesymbol_syn
Nop25
resolver
uniprot_entry
NOL12_RAT
resolver
amino_acid_sequence
MGRNKKKKRDGDDRRPRLILNFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTVSDLDLSGARLLGLPLPEQGDQDGSQEEEVSSMEKPTKALPKKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHNGE
uniprot
proteins
function
FUNCTION: Multifunctional RNA binding protein that plays a role in RNA metabolism and DNA maintenance. Participates in the resolution of DNA stress and the maintenance of genome integrity by localizing to sites of DNA insults. Also plays a role in proper nucleolar organization by limiting nucleolar size and regulating nucleolar number. Mechanistically, regulates the nucleolar levels of fibrillarin and nucleolin, two key players in pre-rRNA processing and ribosome assembly. {ECO:0000250|UniProtKB:Q9UGY1}.
uniprot
proteins
mass_dalton
25186
uniprot
proteins
protein_family
RRP17 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16430885
uniprot
proteins
sequence_length
216
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9UGY1}. Nucleus {ECO:0000250|UniProtKB:Q9UGY1}. Cytoplasm {ECO:0000250|UniProtKB:Q9UGY1}.
uniprot
proteins