CADPS
entrez
8618
canonical
uniprot
Q9ULU8
canonical
ensembl
ENSG00000163618
resolver
ensp
ENSP00000283269
resolver
ensp
ENSP00000350632
resolver
ensp
ENSP00000373215
resolver
ensp
ENSP00000484365
resolver
ensp
ENSP00000605233
resolver
ensp
ENSP00000621751
resolver
ensp
ENSP00000621752
resolver
ensp
ENSP00000621753
resolver
ensp
ENSP00000621754
resolver
enst
ENST00000612439
resolver
genesymbol
CADPS
resolver
genesymbol_syn
CAPS
resolver
genesymbol_syn
CAPS1
resolver
genesymbol_syn
KIAA1121
resolver
hgnc
HGNC:1426
resolver
uniprot
A0A087X1P6
resolver
uniprot
A6NF60
resolver
uniprot
F1T0E5
resolver
uniprot
Q13339
resolver
uniprot
Q6GQQ6
resolver
uniprot
Q8N2Z5
resolver
uniprot
Q8N3M7
resolver
uniprot
Q8NFR0
resolver
uniprot
Q96BC2
resolver
uniprot_entry
A0A087X1P6_HUMAN
resolver
uniprot_entry
CAPS1_HUMAN
resolver
uniprot_entry
F1T0E5_HUMAN
resolver
uniprot_sec
A6NF60
resolver
uniprot_sec
Q13339
resolver
uniprot_sec
Q6GQQ6
resolver
uniprot_sec
Q8N2Z5
resolver
uniprot_sec
Q8N3M7
resolver
uniprot_sec
Q8NFR0
resolver
uniprot_sec
Q96BC2
resolver
amino_acid_sequence
MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVGAGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQLYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAKFDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD
uniprot
proteins
function
FUNCTION: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
152786
uniprot
proteins
pubmed
10574461
uniprot
proteins
pubmed
12168954
uniprot
proteins
pubmed
12659812
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15857609
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
9289490
uniprot
proteins
sequence_length
1353
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Synapse {ECO:0000250|UniProtKB:Q62717}. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane {ECO:0000250|UniProtKB:Q62717}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q62717}. Note=Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Preferentially binds to dense core vesicles but not to synaptic vesicles. Binds phosphoinosides, with a strong selectivity for PtdIns(4,5)P2 over PtdIns(3,4,5)P3. Probably localizes to different vesicles compared to CADPS2. {ECO:0000250|UniProtKB:Q62717}.
uniprot
proteins