TNFRSF18
entrez
8784
canonical
uniprot
Q9Y5U5
canonical
ensembl
ENSG00000186891
resolver
ensp
ENSP00000328207
resolver
ensp
ENSP00000368567
resolver
ensp
ENSP00000368570
resolver
genesymbol
TNFRSF18
resolver
genesymbol_syn
AITR
resolver
genesymbol_syn
GITR
resolver
hgnc
HGNC:11914
resolver
uniprot
A0A0R7FDM1
resolver
uniprot
B1AME1
resolver
uniprot
O95851
resolver
uniprot
Q5U0I4
resolver
uniprot
Q9NYJ9
resolver
uniprot_entry
A0A0R7FDM1_HUMAN
resolver
uniprot_entry
TNR18_HUMAN
resolver
uniprot_sec
B1AME1
resolver
uniprot_sec
O95851
resolver
uniprot_sec
Q5U0I4
resolver
uniprot_sec
Q9NYJ9
resolver
amino_acid_sequence
MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
uniprot
proteins
function
FUNCTION: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
uniprot
proteins
mass_dalton
26000
uniprot
proteins
pubmed
10037686
uniprot
proteins
pubmed
10074428
uniprot
proteins
pubmed
10836847
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
sequence_length
241
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
uniprot
proteins
transmembrane_region
TRANSMEM 163..183; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins