Tlcd1
entrez
68385
canonical
uniprot
Q99JT6
canonical
ensembl
ENSMUSG00000019437
resolver
ensp
ENSMUSP00000090556
resolver
ensp
ENSMUSP00000114202
resolver
genesymbol
Tlcd1
resolver
uniprot
Q3V372
resolver
uniprot
Q5SYM9
resolver
uniprot
Q8CHT9
resolver
uniprot
Q9DCK5
resolver
uniprot_entry
TLCD1_MOUSE
resolver
uniprot_sec
Q3V372
resolver
uniprot_sec
Q5SYM9
resolver
uniprot_sec
Q8CHT9
resolver
uniprot_sec
Q9DCK5
resolver
amino_acid_sequence
MPLLFHPAWPLLLGATLTFRALRRVLCRLPQPAHVQTDPLRTWRWHNLLVSFTHSIVSGIWALLCLWQTPEMLVEIETAWSASGYLLVCFSAGYFIHDTVDIVVSKQTRASWEYLVHHVMAMGAFFSGIFWKRFVGGGVLTLLVEVSNIFLTLRMMMKINNAQDLLLYKVNKYINLVMYFLFRLAPQAYLTKFFLQYAGQRTLGTFLLAILLMLDLMIIIYFSRLLRSDFCPERAPRRQQKDKFLTE
uniprot
proteins
function
FUNCTION: Regulates the composition and fluidity of the plasma membrane (By similarity). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity). Does not appear to have any effect on LCPUFA synthesis (By similarity). {ECO:0000250|UniProtKB:Q96CP7}.
uniprot
proteins
mass_dalton
28787
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
247
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q96CP7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F1NZP5}.
uniprot
proteins
transmembrane_region
TRANSMEM 47..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 84..104; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins