RETSAT
entrez
54884
canonical
uniprot
Q6NUM9
canonical
ensembl
ENSG00000042445
resolver
ensembl
ENSG00000292155
resolver
ensp
ENSP00000295802
resolver
ensp
ENSP00000691327
resolver
genesymbol
RETSAT
resolver
genesymbol_syn
PPSIG
resolver
hgnc
HGNC:25991
resolver
uniprot
A6NIK3
resolver
uniprot
Q53R95
resolver
uniprot
Q53SA9
resolver
uniprot
Q6UX05
resolver
uniprot
Q8N2H5
resolver
uniprot
Q96FA4
resolver
uniprot
Q9NXE5
resolver
uniprot_entry
RETST_HUMAN
resolver
uniprot_sec
A6NIK3
resolver
uniprot_sec
Q53R95
resolver
uniprot_sec
Q53SA9
resolver
uniprot_sec
Q6UX05
resolver
uniprot_sec
Q8N2H5
resolver
uniprot_sec
Q96FA4
resolver
uniprot_sec
Q9NXE5
resolver
amino_acid_sequence
MWLPLVLLLAVLLLAVLCKVYLGLFSGSSPNPFSEDVKRPPAPLVTDKEARKKVLKQAFSANQVPEKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGGCCHTFGKNGLEFDTGIHYIGRMEEGSIGRFILDQITEGQLDWAPLSSPFDIMVLEGPNGRKEYPMYSGEKAYIQGLKEKFPQEEAIIDKYIKLVKVVSSGAPHAILLKFLPLPVVQLLDRCGLLTRFSPFLQASTQSLAEVLQQLGASSELQAVLSYIFPTYGVTPNHSAFSMHALLVNHYMKGGFYPRGGSSEIAFHTIPVIQRAGGAVLTKATVQSVLLDSAGKACGVSVKKGHELVNIYCPIVVSNAGLFNTYEHLLPGNARCLPGVKQQLGTVRPGLGMTSVFICLRGTKEDLHLPSTNYYVYYDTDMDQAMERYVSMPREEAAEHIPLLFFAFPSAKDPTWEDRFPGRSTMIMLIPTAYEWFEEWQAELKGKRGSDYETFKNSFVEASMSVVLKLFPQLEGKVESVTAGSPLTNQFYLAAPRGACYGADHDLGRLHPCVMASLRAQSPIPNLYLTGQDIFTCGLVGALQGALLCSSAILKRNLYSDLKNLDSRIRAQKKKN
uniprot
proteins
ec_number
1.3.99.23
uniprot
proteins
function
FUNCTION: Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation. {ECO:0000250|UniProtKB:Q64FW2}.
uniprot
proteins
mass_dalton
66820
uniprot
proteins
protein_family
Carotenoid/retinoid oxidoreductase family
uniprot
proteins
protein_family
CrtISO subfamily
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
19139408
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
28855500
uniprot
proteins
sequence_length
610
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q64FW2}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q64FW2}.
uniprot
proteins