Scarb1
entrez
25073
canonical
uniprot
P97943
canonical
ensembl
ENSRNOG00000000981
resolver
ensp
ENSRNOP00000001299
resolver
ensp
ENSRNOP00000085701
resolver
genesymbol
Scarb1
resolver
uniprot_entry
SCRB1_RAT
resolver
amino_acid_sequence
MGVSSRARWVALGLGVLGLLCAALGVIMILMVPSLIKQQVLKNVRIDPSSLSFGMWKEIPVPFYLSVYFFEVVNPSEVLNGQKPVVRERGPYVYREFRQKVNITFNDNDTVSYIENRSLRFQPDRSQGSESDYIVLPNILVLGGAVMMEDKPTSLKLLMTLGLVTMGQRAFMNRTVGEILWGYEDPFVNFLSKYFPDMFPIKGKFGLFVGMNDSSSGVFTVFTGVQNFSKIHLVDKWNGLSEVNYWHSEQCNMINGTAGQMWAPFMTPESSLEFFSPEACRSMKLTYQESRVFEGIPTYRFTAPDTLFANGSVYPPNEGFCPCRESGIQNVSTCRFGAPLFLSQPHFYNADPVLSEAVLGLNPDPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGVGQTGKIEPVVLPLLWFEQSGMMGGKTLNTFYTQLVLMPQVLHYAQYVLLGLGGLLLLVPIIYQLRSQEKCFLFWSGSKKGSQDKEAMQAYSESLMSPAAKGTVLQEAKL
uniprot
proteins
function
FUNCTION: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. {ECO:0000250|UniProtKB:Q8WTV0}.
uniprot
proteins
mass_dalton
56957
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:12016218}.; PTM: The six cysteines of the extracellular domain are all involved in intramolecular disulfide bonds. {ECO:0000250}.
uniprot
proteins
protein_family
CD36 family
uniprot
proteins
pubmed
10829064
uniprot
proteins
pubmed
12016218
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9177301
uniprot
proteins
pubmed
9291126
uniprot
proteins
sequence_length
509
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8WTV0}; Multi-pass membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250|UniProtKB:Q61009}; Multi-pass membrane protein {ECO:0000250}. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 12..32; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 441..461; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins