TRNP1
entrez
388610
canonical
uniprot
Q6NT89
canonical
ensembl
ENSG00000253368
resolver
ensp
ENSP00000429216
resolver
ensp
ENSP00000436467
resolver
enst
ENST00000522111
resolver
enst
ENST00000531285
resolver
genesymbol
TRNP1
resolver
genesymbol_syn
C1orf225
resolver
genesymbol_syn
TRNP
resolver
hgnc
HGNC:34348
resolver
uniprot_entry
TRNP1_HUMAN
resolver
amino_acid_sequence
MPGCRISACGPGAQEGTAEQRSPPPPWDPMPSSQPPPPTPTLTPTPTPGQSPPLPDAAGASAGAAEDQELQRWRQGASGIAGLAGPGGGSGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGPRRGRRGRPPALLASALGLGGCVPWGAGRLRRGHGPEPDSPFRRSPPRGPASPQR
uniprot
proteins
function
FUNCTION: DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex. Regulates neural stem cells proliferation and the production of intermediate neural progenitors and basal radial glial cells affecting the process of cerebral cortex gyrification. May control the proliferation rate of cells by regulating their progression through key cell-cycle transition points (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
23482
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation by the proteasome. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
23622239
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins