Tnfrsf13c
entrez
72049
canonical
uniprot
Q9D8D0
canonical
ensembl
ENSMUSG00000068105
resolver
ensp
ENSMUSP00000086564
resolver
ensp
ENSMUSP00000154899
resolver
enst
ENSMUST00000231049
resolver
genesymbol
Tnfrsf13c
resolver
genesymbol_syn
Baffr
resolver
genesymbol_syn
Bcmd
resolver
genesymbol_syn
Br3
resolver
uniprot
A0A2R8W6G5
resolver
uniprot
Q3SXS6
resolver
uniprot
Q3SXS7
resolver
uniprot_entry
A0A2R8W6G5_MOUSE
resolver
uniprot_entry
Q3SXS6_MOUSE
resolver
uniprot_entry
Q3SXS7_MOUSE
resolver
uniprot_entry
TR13C_MOUSE
resolver
amino_acid_sequence
MGARRLRVRSQRSRDSSVPTQCNQTECFDPLVRNCVSCELFHTPDTGHTSSLEPGTALQPQEGSALRPDVALLVGAPALLGLILALTLVGLVSLVSWRWRQQLRTASPDTSEGVQQESLENVFVPSSETPHASAPTWPPLKEDADSALPRHSVPVPATELGSTELVTTKTAGPEQ
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Tnfrsf13c are a cause of severe B-cell deficiency. B-cell deficient strain A/WySnJ has a 4.7 kb insertion in the BAFFR gene leading to an altered C-terminus. The mutant RNA is not detectable. B-cell lymphopoiesis is normal, but the life span of peripheral B-cells is much reduced. {ECO:0000269|PubMed:11591325}.
uniprot
proteins
function
FUNCTION: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. {ECO:0000269|PubMed:11747827}.
uniprot
proteins
mass_dalton
18798
uniprot
proteins
pubmed
11509692
uniprot
proteins
pubmed
11591325
uniprot
proteins
pubmed
11747827
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 72..92; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins