Ift172
entrez
67661
canonical
uniprot
Q6VH22
canonical
ensembl
ENSMUSG00000038564
resolver
ensp
ENSMUSP00000049335
resolver
genesymbol
Ift172
resolver
genesymbol_syn
Kiaa1179
resolver
genesymbol_syn
Wim
resolver
uniprot
Q6NZK1
resolver
uniprot
Q80TI4
resolver
uniprot
Q80W19
resolver
uniprot
Q9DAB0
resolver
uniprot_entry
IF172_MOUSE
resolver
uniprot_sec
Q6NZK1
resolver
uniprot_sec
Q80TI4
resolver
uniprot_sec
Q80W19
resolver
uniprot_sec
Q9DAB0
resolver
amino_acid_sequence
MQLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYVIVFGLAEGKVRLANTKTNKSSTIYGTESYVVALTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRRIVAYGKEGHVLQTFDYSRDPQEREFTTAAASPGGQSVVLGSYDRLRVFNWSPRRSIWEEAKPKEIANLYTVTALAWKRDGSRLCAGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSDTLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGSNDSLGSVRTEFMNPHLISVRINERCQRGMEDNKKLAYLVDIKTIAIVDLIGGYNIGTISHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYVQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMSSIRGDVVGLERGGGKTEVMVTEGVTTVAYTLDEGLIEFGTAIDDGNYTRATAFLETLEMTPETEAMWKTLSKLALEARQLHTAERCFSALGHVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMDMYQELHRWEECIAVAEAKGHPALEKLRRDYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITTALIKGELYERAGDLFEKIRNPQRALECYCKGNAFMKAVELARLAFPVEVVRLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPRVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVEEPDLAITMFKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRSSGLWEEAYRVAKAHGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEATIDHAADNCSFEFAFELSRLAFKHKAPEIHLKYAMYLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPGQLEALQEEYEREATKKGGRGVEGLVEQARQWEQAGEYSRAVDCYLKVRDSGSSGLMEKCWMKAAELSIKFLPPQRSLEVVRVVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVVAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGGYAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNNAEAYHSWADLRDVLFNLCENLVKSSEANSAAHEEFEMMLLISHYYATRSAAQSIKQLETVAARLSVSLLRHTQLLPADKAFYEAGTAAKEVGWENMAFIFLNRFLDLTDAIEEGTLDALDHSDFQDTDIPFEVPLPAKQHVPEAQREEVRDWVLTVSMDQRLEQVLPRDERGVYEASLVAASTGVRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ
uniprot
proteins
function
FUNCTION: Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway. {ECO:0000269|PubMed:14603322, ECO:0000269|PubMed:16061793}.
uniprot
proteins
mass_dalton
197548
uniprot
proteins
mutagenesis
MUTAGEN 1564; /note="L->P: In wim; embryos arrest at 10.5-11.5 dpc and display an open neural tube in the head that lack the normal groove on the ventral midline. They lack ventral neural cell types and display other phenotypes characteristic of defects in Sonic hedgehog signaling."; /evidence="ECO:0000269|PubMed:14603322
uniprot
proteins
protein_family
IFT172 family
uniprot
proteins
pubmed
11062270
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
14603322
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16061793
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23055941
uniprot
proteins
pubmed
23810713
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24339785
uniprot
proteins
sequence_length
1749
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000305}.
uniprot
proteins