Kif5a
entrez
16572
canonical
uniprot
P33175
canonical
ensembl
ENSMUSG00000074657
resolver
ensp
ENSMUSP00000096775
resolver
ensp
ENSMUSP00000151402
resolver
enst
ENSMUST00000099172
resolver
enst
ENSMUST00000217895
resolver
genesymbol
Kif5a
resolver
genesymbol_syn
Kiaa4086
resolver
genesymbol_syn
Kif5
resolver
genesymbol_syn
Nkhc1
resolver
uniprot
Q3US62
resolver
uniprot
Q5DTP1
resolver
uniprot
Q6PDY7
resolver
uniprot
Q9Z2F9
resolver
uniprot_entry
KIF5A_MOUSE
resolver
uniprot_entry
Q3US62_MOUSE
resolver
uniprot_sec
Q5DTP1
resolver
uniprot_sec
Q6PDY7
resolver
uniprot_sec
Q9Z2F9
resolver
amino_acid_sequence
MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVIIGGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENVETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEDSALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMRDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQTVELKKRHLEESYDSLSDELARLQAHETVHEVALKDKEPDTQDAEEVKKALELQMENHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYERLKNEENEKSAKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPECISYTNNLFQNYQNLHLQAAPSSTSDMYFASSGATSVAPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQAKLFPLHQETAAS
uniprot
proteins
ec_number
5.6.1.3
uniprot
proteins
function
FUNCTION: Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (PubMed:12682084). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons (PubMed:21976701). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity). {ECO:0000250|UniProtKB:Q6QLM7, ECO:0000269|PubMed:12682084, ECO:0000269|PubMed:21976701}.
uniprot
proteins
mass_dalton
117019
uniprot
proteins
mutagenesis
MUTAGEN 93; /note="T->N: Loss of ability to induce formation of neurite-like membrane protrusions in non-neuronal cells."; /evidence="ECO:0000269|PubMed:21976701
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
Kinesin subfamily
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
11986669
uniprot
proteins
pubmed
12682084
uniprot
proteins
pubmed
1447303
uniprot
proteins
pubmed
14600269
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18539120
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21976701
uniprot
proteins
pubmed
24251978
uniprot
proteins
pubmed
9782088
uniprot
proteins
sequence_length
1027
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q6QLM7}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q6QLM7}. Perikaryon {ECO:0000250|UniProtKB:Q6QLM7}. Note=Concentrated in the cell body of the neurons, particularly in the perinuclear region. {ECO:0000250|UniProtKB:Q6QLM7}.
uniprot
proteins