MON1A
entrez
84315
canonical
uniprot
Q86VX9
canonical
ensembl
ENSG00000164077
resolver
ensp
ENSP00000296473
resolver
ensp
ENSP00000404793
resolver
ensp
ENSP00000494452
resolver
ensp
ENSP00000534214
resolver
genesymbol
MON1A
resolver
genesymbol_syn
SAND1
resolver
hgnc
HGNC:28207
resolver
uniprot
B2RDQ1
resolver
uniprot
G5E9N1
resolver
uniprot
Q8NAV7
resolver
uniprot
Q9BRF3
resolver
uniprot
X6R3V9
resolver
uniprot_entry
MON1A_HUMAN
resolver
uniprot_sec
B2RDQ1
resolver
uniprot_sec
G5E9N1
resolver
uniprot_sec
Q8NAV7
resolver
uniprot_sec
Q9BRF3
resolver
uniprot_sec
X6R3V9
resolver
amino_acid_sequence
MHPGGGPSRAERLELGLGRERPAKAIFLHRRPGEGGGRERCLRCGHVCVRRGPGPREAVPSGRPRPDTLTPPWVRQRAVTGTFCASWTPLRNRRAQRMATDMQRKRSSECLDGTLTPSDGQSMERAESPTPGMAQGMEPGAGQEGAMFVHARSYEDLTESEDGAASGDSHKEGTRGPPPLPTDMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPPGAVGRPATEPPREGTTEGDEEDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHADGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDPSFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSILLARNQLVALVRRKDQFLHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALRTPYYSVAQVGIPDLRHFLYKSKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY
uniprot
proteins
function
FUNCTION: Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991). {ECO:0000250|UniProtKB:Q6PDG8, ECO:0000269|PubMed:23084991}.
uniprot
proteins
mass_dalton
72895
uniprot
proteins
protein_family
MON1/SAND family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
23084991
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
29038162
uniprot
proteins
pubmed
34432599
uniprot
proteins
pubmed
40174224
uniprot
proteins
sequence_length
652
uniprot
proteins