CCIN
entrez
881
canonical
uniprot
Q13939
canonical
ensembl
ENSG00000185972
resolver
ensp
ENSP00000334996
resolver
enst
ENST00000335119
resolver
genesymbol
CCIN
resolver
hgnc
HGNC:1568
resolver
uniprot
Q8WWB2
resolver
uniprot
Q8WX35
resolver
uniprot
Q9BXG7
resolver
uniprot_entry
CALI_HUMAN
resolver
uniprot_entry
Q8WWB2_HUMAN
resolver
uniprot_entry
Q8WX35_HUMAN
resolver
uniprot_sec
Q9BXG7
resolver
amino_acid_sequence
MKLEFTEKNYNSFVLQNLNRQRKRKEYWDMALSVDNHVFFAHRNVLAAVSPLVRSLISSNDMKTADELFITIDTSYLSPVTVDQLLDYFYSGKVVISEQNVEELLRGAQYFNTPRLRVHCNDFLIKSICRANCLRYLFLAELFELKEVSDVAYSGIRDNFHYWASPEGSMHFMRCPPVIFGRLLRDENLHVLNEDQALSALINWVYFRKEDREKYFKKFFNYINLNAVSNKTLVFASNKLVGMENTSSHTTLIESVLMDRKQERPCSLLVYQRKGALLDSVVILGGQKAHGQFNDGVFAYIIQENLWMKLSDMPYRAAALSATSAGRYIYISGGTTEQISGLKTAWRYDMDDNSWTKLPDLPIGLVFHTMVTCGGTVYSVGGSIAPRRYVSNIYRYDERKEVWCLAGKMSIPMDGTAVITKGDRHLYIVTGRCLVKGYISRVGVVDCFDTSTGDVVQCITFPIEFNHRPLLSFQQDNILCVHSHRQSVEINLQKVKASKTTTSVPVLPNSCPLDVSHAICSIGDSKVFVCGGVTTASDVQTKDYTINPNAFLLDQKTGKWKTLAPPPEALDCPACCLAKLPCKILQRI
uniprot
proteins
disease_involvement
DISEASE: Spermatogenic failure 91 (SPGF91) [MIM:620838]: An autosomal recessive, male infertility disorder due to globozoospermia and asthenoteratozoospermia. Patient sperm show defects of the head, including a misshapen rounded head and detachment of the acrosome, and the sperm fail to attach to the zona pellucida of the egg. {ECO:0000269|PubMed:31985809, ECO:0000269|PubMed:36527329, ECO:0000269|PubMed:36546111}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Required for both nuclear and acrosomal shaping during spermiogenesis. {ECO:0000269|PubMed:36546111}.
uniprot
proteins
mass_dalton
66582
uniprot
proteins
pubmed
31985809
uniprot
proteins
pubmed
36527329
uniprot
proteins
pubmed
36546111
uniprot
proteins
pubmed
38573307
uniprot
proteins
pubmed
7641791
uniprot
proteins
sequence_length
588
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, perinuclear theca, calyx {ECO:0000269|PubMed:36527329, ECO:0000269|PubMed:36546111}.
uniprot
proteins