Syp
entrez
20977
canonical
uniprot
Q62277
canonical
ensembl
ENSMUSG00000031144
resolver
ensp
ENSMUSP00000069429
resolver
enst
ENSMUST00000069520
resolver
genesymbol
Syp
resolver
uniprot
Q8BRQ0
resolver
uniprot
Q91WI8
resolver
uniprot_entry
SYPH_MOUSE
resolver
uniprot_sec
Q8BRQ0
resolver
uniprot_sec
Q91WI8
resolver
amino_acid_sequence
MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYTGELRLSVECANKTESALNIEVEFEYPFRLHQVYFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFMRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPASGGGGGYGPQGDYGQQGYGQQGAPTSFSNQM
uniprot
proteins
function
FUNCTION: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane (By similarity). Involved in the regulation of short-term and long-term synaptic plasticity. {ECO:0000250, ECO:0000269|PubMed:10595519}.
uniprot
proteins
mass_dalton
34025
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. {ECO:0000250}.; PTM: Phosphorylated by SRC. {ECO:0000250|UniProtKB:P07825}.
uniprot
proteins
protein_family
Synaptophysin/synaptobrevin family
uniprot
proteins
pubmed
10595519
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
19196426
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24995978
uniprot
proteins
pubmed
9210520
uniprot
proteins
sequence_length
314
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:24995978}; Multi-pass membrane protein {ECO:0000255}. Synapse, synaptosome {ECO:0000250|UniProtKB:P08247}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..49; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 108..131; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..162; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..224; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins