COX17
entrez
10063
canonical
uniprot
Q14061
canonical
ensembl
ENSG00000138495
resolver
ensp
ENSP00000261070
resolver
ensp
ENSP00000417651
resolver
ensp
ENSP00000417805
resolver
ensp
ENSP00000417923
resolver
ensp
ENSP00000566641
resolver
ensp
ENSP00000566643
resolver
ensp
ENSP00000566644
resolver
ensp
ENSP00000581360
resolver
ensp
ENSP00000581363
resolver
ensp
ENSP00000628329
resolver
enst
ENST00000261070
resolver
enst
ENST00000468918
resolver
enst
ENST00000484810
resolver
enst
ENST00000497116
resolver
enst
ENST00000896582
resolver
enst
ENST00000896584
resolver
enst
ENST00000896585
resolver
enst
ENST00000911301
resolver
enst
ENST00000911304
resolver
enst
ENST00000958270
resolver
genesymbol
COX17
resolver
hgnc
HGNC:2264
resolver
uniprot
B2R5D2
resolver
uniprot
C9J8T6
resolver
uniprot
D3DN84
resolver
uniprot
Q3MHD6
resolver
uniprot_entry
C9J8T6_HUMAN
resolver
uniprot_entry
COX17_HUMAN
resolver
uniprot_sec
B2R5D2
resolver
uniprot_sec
D3DN84
resolver
uniprot_sec
Q3MHD6
resolver
amino_acid_sequence
MPGLVDSNPAPPESQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI
uniprot
proteins
function
FUNCTION: Copper metallochaperone involved in the assembly of cytochrome c oxidase (respiratory chain complex IV, CIV) (PubMed:15229189, PubMed:19393246, PubMed:31903891, PubMed:35750769). Binds two copper ions and delivers them to metallochaperones SCO1 and SCO2, which co-chaperone the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2), and to metallochaperone COX11 which relays the copper to the Cu(B) site on the cytochrome c oxidase subunit I (MT-CO1/COX1) (PubMed:15229189, PubMed:19393246, PubMed:35750769). {ECO:0000269|PubMed:15229189, ECO:0000269|PubMed:19393246, ECO:0000269|PubMed:31903891, ECO:0000269|PubMed:35750769}.
uniprot
proteins
mass_dalton
6915
uniprot
proteins
post_translational_modification
PTM: Acetylation by KAT8 promotes assembly of the mitochondrial respiratory chain complex IV (CIV). {ECO:0000250|UniProtKB:P56394}.
uniprot
proteins
protein_family
COX17 family
uniprot
proteins
pubmed
10982038
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15229189
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18093982
uniprot
proteins
pubmed
19393246
uniprot
proteins
pubmed
21059946
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21816817
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22356826
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
31903891
uniprot
proteins
pubmed
35750769
uniprot
proteins
pubmed
9050918
uniprot
proteins
sequence_length
63
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000269|PubMed:19393246, ECO:0000305|PubMed:35750769}. Cytoplasm {ECO:0000269|PubMed:19393246}.
uniprot
proteins