OR1A2
entrez
26189
canonical
uniprot
Q9Y585
canonical
ensembl
ENSG00000172150
resolver
ensp
ENSP00000371377
resolver
enst
ENST00000381951
resolver
genesymbol
OR1A2
resolver
hgnc
HGNC:8180
resolver
uniprot
Q3KPH3
resolver
uniprot
Q6IFM0
resolver
uniprot
Q6NTD8
resolver
uniprot
Q96R86
resolver
uniprot_entry
OR1A2_HUMAN
resolver
uniprot_sec
Q3KPH3
resolver
uniprot_sec
Q6IFM0
resolver
uniprot_sec
Q6NTD8
resolver
uniprot_sec
Q96R86
resolver
amino_acid_sequence
MKKENQSFNLDFILLGVTSQQEQNNVFFVIFLCIYPITLTGNLLIILAICADIRLHNPMYFLLANLSLVDIIFSSVTIPKVLANHLLGSKFISFGGCLMQMYFMIALAKADSYTLAAMAYDRAVAISCPLHYTTIMSPRSCILLIAGSWVIGNTSALPHTLLTASLSFCGNQEVANFYCDIMPLLKLSCSDVHFNVKMMYLGVGVFSLPLLCIIVSYVQVFSTVFQVPSTKSLFKAFCTCGSHLTVVFLYYGTTMGMYFRPLTSYSPKDAVITVMYVAVTPALNPFIYSLRNWDMKAALQKLFSKRISS
uniprot
proteins
function
FUNCTION: Olfactory receptor activated by citronellal, a citronellic terpenoid often described as having citrus, fruity or herbal smells (PubMed:17601748). Ligand-binding causes a conformation change that triggers signaling via G(s)-class of G alpha protein GNAL/G(olf), mediating activation of adenylate cyclase activity and increased production of cAMP, initiating a neuronal response that triggers the perception of a smell (By similarity). {ECO:0000250|UniProtKB:Q9P1Q5, ECO:0000269|PubMed:17601748}.
uniprot
proteins
mass_dalton
34396
uniprot
proteins
mutagenesis
MUTAGEN 108; /note="A->G: Promotes activation by citronellol."; /evidence="ECO:0000269|PubMed:17601748"; MUTAGEN 109; /note="K->N: Promotes activation by citronellol."; /evidence="ECO:0000269|PubMed:17601748
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10673334
uniprot
proteins
pubmed
12213199
uniprot
proteins
pubmed
14983052
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17601748
uniprot
proteins
sequence_length
309
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17601748}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..49; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 58..79; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 101..120; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 140..158; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 196..218; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 236..258; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 271..290; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins