Tfap2e
entrez
332937
canonical
uniprot
Q6VUP9
canonical
ensembl
ENSMUSG00000042477
resolver
ensp
ENSMUSP00000035902
resolver
enst
ENSMUST00000048194
resolver
genesymbol
Tfap2e
resolver
genesymbol_syn
Tcfap2e
resolver
uniprot
A2A883
resolver
uniprot_entry
AP2E_MOUSE
resolver
uniprot_sec
A2A883
resolver
amino_acid_sequence
MLVHTYSAMERPDGLGAAAGGTRLSSLPQAAYGPAPPLCHTPAASATADYHPPYFPPPYPQAPLPYGQGPDATAAFPHLAADPYGGLAPLAQPQPPQAAWAAPRAAARAHDEPPGLLAPPARALGLDPRRDYAAAVPRLLHSLADGAHGLADAPLGLPGLAEPPGLEELQAIDDPGMSLLDQSVIKKVPIPSKAGSLSTLALSKDSLVGGISNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLEKMFLSGAGGGHGESKASEKDTKHRK
uniprot
proteins
function
FUNCTION: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation. {ECO:0000269|PubMed:14572467, ECO:0000269|PubMed:14636996, ECO:0000269|PubMed:16684505}.
uniprot
proteins
mass_dalton
46283
uniprot
proteins
protein_family
AP-2 family
uniprot
proteins
pubmed
14572467
uniprot
proteins
pubmed
14636996
uniprot
proteins
pubmed
16684505
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
442
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16684505}.
uniprot
proteins