Nfkbil1
entrez
18038
canonical
uniprot
O88995
canonical
ensembl
ENSMUSG00000042419
resolver
ensp
ENSMUSP00000035452
resolver
enst
ENSMUST00000048994
resolver
genesymbol
Nfkbil1
resolver
genesymbol_syn
Ikbl
resolver
uniprot
Q91X16
resolver
uniprot
Q9R1Y3
resolver
uniprot_entry
IKBL1_MOUSE
resolver
uniprot_sec
Q91X16
resolver
uniprot_sec
Q9R1Y3
resolver
amino_acid_sequence
MSNPSPQAPEEEASTSVCRPQSCSMASASRRHRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEDEEVSKEREWRQKLQGELEDEWQEVIGRFEDDASRDTQEPESFSAWSERLAREHAQKQRQQLEAEGSCRPPRAEGSSHSWRQHEEEQRLFRERARAKEKELCESRARRAQEAQRDKGPEPPRAGPRAEHPRGAERGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALKRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
uniprot
proteins
function
FUNCTION: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
43202
uniprot
proteins
pubmed
10023090
uniprot
proteins
pubmed
14656967
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
381
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus (By similarity). {ECO:0000250}.
uniprot
proteins