TAF2
entrez
6873
canonical
uniprot
Q6P1X5
canonical
ensembl
ENSG00000064313
resolver
ensp
ENSP00000367406
resolver
ensp
ENSP00000509206
resolver
ensp
ENSP00000509978
resolver
ensp
ENSP00000510174
resolver
enst
ENST00000378164
resolver
enst
ENST00000685235
resolver
enst
ENST00000686879
resolver
enst
ENST00000688645
resolver
genesymbol
TAF2
resolver
genesymbol_syn
CIF150
resolver
genesymbol_syn
TAF2B
resolver
hgnc
HGNC:11536
resolver
uniprot
A0A8I5KSY6
resolver
uniprot
A0A8I5KV60
resolver
uniprot
A0A8I5QJR0
resolver
uniprot
B2RE82
resolver
uniprot
B3KMD8
resolver
uniprot
O43487
resolver
uniprot
O43604
resolver
uniprot
O60668
resolver
uniprot
Q86WW7
resolver
uniprot
Q8IWK4
resolver
uniprot_entry
A0A8I5KSY6_HUMAN
resolver
uniprot_entry
A0A8I5KV60_HUMAN
resolver
uniprot_entry
A0A8I5QJR0_HUMAN
resolver
uniprot_entry
B3KMD8_HUMAN
resolver
uniprot_entry
TAF2_HUMAN
resolver
uniprot_sec
B2RE82
resolver
uniprot_sec
O43487
resolver
uniprot_sec
O43604
resolver
uniprot_sec
O60668
resolver
uniprot_sec
Q86WW7
resolver
uniprot_sec
Q8IWK4
resolver
amino_acid_sequence
MPLTGVEPARMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDLEAAFIYNDPTLEVCHSESKQRNLNYFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLKIHINFSLDQPKGGLHFVVPSVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLTIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQSLAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKEELDKIVAYELKTGGVLLHPIFGGGKEKDNPASHLHFSIKHPHTLSWEYYSMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNKKKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQADFMWQYQLRYERDVVAQQESILALEKFPTPASRLALTDILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKSCPNIVKTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEMIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNMEKLLPSYRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIRIAALEAVVDYTKVDRSYEELQWLLNMIQNDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSGTSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVAGNQEAANNPSSHPQLVGFQNPFSSSQDEEEIDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTKESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPSLSD
uniprot
proteins
disease_involvement
DISEASE: Neurodevelopmental disorder with feeding difficulties, thin corpus callosum, and foot deformity (NEDFCF) [MIM:615599]: An autosomal recessive disorder characterized by impaired intellectual development, microcephaly, delayed psychomotor development, pyramidal signs, thin corpus callosum, and foot deformity. {ECO:0000269|PubMed:21937992, ECO:0000269|PubMed:24084144}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473, PubMed:9418870, PubMed:9774672). TAF2 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF1 (PubMed:33795473, PubMed:9774672). {ECO:0000269|PubMed:33795473, ECO:0000269|PubMed:9418870, ECO:0000269|PubMed:9774672}.
uniprot
proteins
mass_dalton
136971
uniprot
proteins
protein_family
TAF2 family
uniprot
proteins
pubmed
12601814
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21937992
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24084144
uniprot
proteins
pubmed
33795473
uniprot
proteins
pubmed
9418870
uniprot
proteins
pubmed
9774672
uniprot
proteins
sequence_length
1199
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9774672}.
uniprot
proteins