RBM38
entrez
55544
canonical
uniprot
Q9H0Z9
canonical
ensembl
ENSG00000132819
resolver
ensp
ENSP00000348538
resolver
ensp
ENSP00000407848
resolver
ensp
ENSP00000669390
resolver
ensp
ENSP00000797202
resolver
genesymbol
RBM38
resolver
genesymbol_syn
RNPC1
resolver
genesymbol_syn
SEB4
resolver
hgnc
HGNC:15818
resolver
uniprot
A6NDK1
resolver
uniprot
A6NMU6
resolver
uniprot
Q15350
resolver
uniprot
Q15351
resolver
uniprot
Q9BYK3
resolver
uniprot
Q9BYK4
resolver
uniprot_entry
RBM38_HUMAN
resolver
uniprot_sec
A6NDK1
resolver
uniprot_sec
A6NMU6
resolver
uniprot_sec
Q15350
resolver
uniprot_sec
Q15351
resolver
uniprot_sec
Q9BYK3
resolver
uniprot_sec
Q9BYK4
resolver
amino_acid_sequence
MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPAAPVPSLSSPYIEYTPASPAYAQYPPATYDQYPYAASPATAASFVGYSYPAAVPQALSAAAPAGTTFVQYQAPQLQPDRMQ
uniprot
proteins
function
FUNCTION: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. {ECO:0000269|PubMed:17050675, ECO:0000269|PubMed:19285943}.; FUNCTION: (Microbial infection) Essential factor for the splicing of the pre-mRNAs of human parvovirus B19 (B19V) and for the expression of B19V 11-kDa protein, which enhances viral replication. {ECO:0000269|PubMed:29437973}.
uniprot
proteins
mass_dalton
25498
uniprot
proteins
protein_family
RBM38 family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12200376
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17050675
uniprot
proteins
pubmed
19285943
uniprot
proteins
pubmed
29437973
uniprot
proteins
sequence_length
239
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:17050675}. Nucleus {ECO:0000269|PubMed:17050675}.
uniprot
proteins