Nelfa
entrez
24116
canonical
uniprot
Q8BG30
canonical
ensembl
ENSMUSG00000029111
resolver
ensp
ENSMUSP00000030993
resolver
ensp
ENSMUSP00000235655
resolver
ensp
ENSMUSP00000235664
resolver
enst
ENSMUST00000030993
resolver
genesymbol
Nelfa
resolver
genesymbol_syn
Whsc2
resolver
genesymbol_syn
Whsc2h
resolver
uniprot
Q8BVE4
resolver
uniprot
Q8VEI7
resolver
uniprot
Q9CSJ9
resolver
uniprot
Q9Z1V9
resolver
uniprot_entry
NELFA_MOUSE
resolver
uniprot_sec
Q8BVE4
resolver
uniprot_sec
Q8VEI7
resolver
uniprot_sec
Q9CSJ9
resolver
uniprot_sec
Q9Z1V9
resolver
amino_acid_sequence
MASMRESDTGLWLHNKLGATDELWAPPSIASLLTAAVIDNIRLCFHRLSSAVKLKLLLGTLHLPRRTVDEMKAALMDIIQLATLDSDPWVLMVADILKSFPDTGSLNLDLEEQNPNVQDILGELREKVSECEASAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLQKSTETAQQLKRSAGVPFHAKGRGLLRKMDTTTPLKGIPKQAPFRSPTTPSVFSPSGNRTPIPPSRTPLQKERGVKLLDISELNTVGAGREAKRRRKTLDTEVVEKPTKEETVVENATPDYAAGLVSTQKLGSLNSEPTLPSTSYLPSTPSVVPASSYIPSSETPPAPPSREASRPPEEPSAPSPTLPTQFKQRAPMYNSGLSPATPAPAAPTSPLTPTTPPAVTPTAQTPPVAMVAPQTQAPAPVQQQPKKNLSLTREQMFAAQEMFKTANKVTRPEKALILGFMAGSRENPCPEQGDVIQIKLSEHTEDLPKADGQGSTTMLVDTVFEMNYATGQWTRFKKYKPMTNVS
uniprot
proteins
function
FUNCTION: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity). {ECO:0000250|UniProtKB:Q9H3P2}.
uniprot
proteins
mass_dalton
57585
uniprot
proteins
protein_family
NELF-A family
uniprot
proteins
pubmed
10409432
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26010750
uniprot
proteins
sequence_length
530
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9H3P2}.
uniprot
proteins