Ppef1
entrez
237178
canonical
uniprot
O35655
canonical
ensembl
ENSMUSG00000062168
resolver
ensp
ENSMUSP00000071191
resolver
enst
ENSMUST00000071204
resolver
genesymbol
Ppef1
resolver
genesymbol_syn
Dres10
resolver
genesymbol_syn
Ppef
resolver
uniprot
A2AIC6
resolver
uniprot_entry
PPE1_MOUSE
resolver
uniprot_sec
A2AIC6
resolver
activity_regulation
ACTIVITY REGULATION: Activated by calcium. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MGCGTSSKKGNKSKKVIKAALVIQNWYRRYRARLRVRQHYALAIFQSIEYSDEQGQMQLSSFFSFMLENYTKTNNEDSALVTRIFDNTRRESQIKDRDDFLGLIEVPDSYDGPRLQFPLTFTDIHILLQAFKQQQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIGTIIDNEILVIHGGISESTDLNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEPDKTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHECKPDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLSYGTMPQFFQYQVTSTSCLNPLHQRMNAMESSAFKILKEKMISRKTDLINAFELRDHSRSGRISLAEWAFSMENILGLNLPWRSLSSHLVTIDSSGSVDYMSSFDDIRIEKPTKDMKSNLTETMYRYRSDLKIIFNIIDSDQSGLISMDEFRTMWKLFNAHYKAHIDDSQIDELASIVDFNKDGNIDFNEFLKAFYVVHKYDKPGTSLA
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Dephosphorylates and destabilises PDCD5 to inhibit TP53/p53-mediated signaling (PubMed:28051100). May have a role in the recovery or adaptation response of photoreceptors (By similarity). {ECO:0000250|UniProtKB:P40421, ECO:0000269|PubMed:28051100}.
uniprot
proteins
mass_dalton
75058
uniprot
proteins
protein_family
PPP phosphatase family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
28051100
uniprot
proteins
pubmed
9215685
uniprot
proteins
sequence_length
650
uniprot
proteins