NCL
entrez
4691
canonical
uniprot
P19338
canonical
ensembl
ENSG00000115053
resolver
ensp
ENSP00000318195
resolver
enst
ENST00000322723
resolver
genesymbol
NCL
resolver
hgnc
HGNC:7667
resolver
uniprot
B3KM80
resolver
uniprot
Q53SK1
resolver
uniprot
Q8NB06
resolver
uniprot
Q9UCF0
resolver
uniprot
Q9UDG1
resolver
uniprot_entry
B3KM80_HUMAN
resolver
uniprot_entry
NUCL_HUMAN
resolver
uniprot_sec
Q53SK1
resolver
uniprot_sec
Q8NB06
resolver
uniprot_sec
Q9UCF0
resolver
uniprot_sec
Q9UDG1
resolver
amino_acid_sequence
MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
uniprot
proteins
function
FUNCTION: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. {ECO:0000269|PubMed:10393184}.
uniprot
proteins
mass_dalton
76614
uniprot
proteins
post_translational_modification
PTM: Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity). {ECO:0000250}.; PTM: Symmetrically methylated by PRMT5. {ECO:0000269|PubMed:21081503}.
uniprot
proteins
pubmed
10393184
uniprot
proteins
pubmed
12147681
uniprot
proteins
pubmed
12429849
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15044383
uniprot
proteins
pubmed
15371412
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17215513
uniprot
proteins
pubmed
17289661
uniprot
proteins
pubmed
17487921
uniprot
proteins
pubmed
17674968
uniprot
proteins
pubmed
17924679
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
19710015
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20221403
uniprot
proteins
pubmed
20858735
uniprot
proteins
pubmed
21081503
uniprot
proteins
pubmed
21242313
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
21474449
uniprot
proteins
pubmed
21536856
uniprot
proteins
pubmed
21700224
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23848194
uniprot
proteins
pubmed
2394707
uniprot
proteins
pubmed
23972994
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24658146
uniprot
proteins
pubmed
24980433
uniprot
proteins
pubmed
25114211
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26103640
uniprot
proteins
pubmed
26845719
uniprot
proteins
pubmed
2737305
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
28589727
uniprot
proteins
pubmed
7718615
uniprot
proteins
pubmed
7993898
uniprot
proteins
pubmed
8321232
uniprot
proteins
sequence_length
710
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:26103640}. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
uniprot
proteins