TMEM170A
entrez
124491
canonical
uniprot
Q8WVE7
canonical
ensembl
ENSG00000166822
resolver
ensp
ENSP00000350230
resolver
ensp
ENSP00000454404
resolver
ensp
ENSP00000455491
resolver
ensp
ENSP00000456194
resolver
ensp
ENSP00000456509
resolver
enst
ENST00000566980
resolver
enst
ENST00000567796
resolver
enst
ENST00000569540
resolver
genesymbol
TMEM170A
resolver
genesymbol_syn
TMEM170
resolver
hgnc
HGNC:29577
resolver
uniprot
B2R4R3
resolver
uniprot
B3KT46
resolver
uniprot
B4DPS4
resolver
uniprot
D3DUK2
resolver
uniprot
H3BPW0
resolver
uniprot
H3BRD7
resolver
uniprot
H3BS26
resolver
uniprot
Q7Z6F3
resolver
uniprot_entry
B3KT46_HUMAN
resolver
uniprot_entry
H3BPW0_HUMAN
resolver
uniprot_entry
H3BRD7_HUMAN
resolver
uniprot_entry
H3BS26_HUMAN
resolver
uniprot_entry
T170A_HUMAN
resolver
uniprot_sec
B2R4R3
resolver
uniprot_sec
B4DPS4
resolver
uniprot_sec
D3DUK2
resolver
uniprot_sec
Q7Z6F3
resolver
amino_acid_sequence
MEREGSGGSGGSAGLLQQILSLKVVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGILTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVLVVSFLRILATL
uniprot
proteins
function
FUNCTION: Acts as a regulator of endoplasmic reticulum (ER) and nuclear envelope (NE) morphogenesis. Affects the ratio between tubular ER and ER sheets by promoting sheet formation at the expense of tubules. Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins (PubMed:26906412). {ECO:0000269|PubMed:26906412}.
uniprot
proteins
mass_dalton
15250
uniprot
proteins
protein_family
TMEM170 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
26906412
uniprot
proteins
sequence_length
144
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:26906412}; Multi-pass membrane protein {ECO:0000255}. Nucleus envelope {ECO:0000269|PubMed:26906412}.
uniprot
proteins
transmembrane_region
TRANSMEM 51..71; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins