Lrig3
entrez
320398
canonical
uniprot
Q6P1C6
canonical
ensembl
ENSMUSG00000020105
resolver
ensp
ENSMUSP00000074360
resolver
enst
ENSMUST00000074807
resolver
genesymbol
Lrig3
resolver
genesymbol_syn
Kiaa3016
resolver
uniprot
Q6ZPE6
resolver
uniprot
Q8BRF0
resolver
uniprot
Q8BS51
resolver
uniprot
Q8C5E4
resolver
uniprot_entry
LRIG3_MOUSE
resolver
uniprot_sec
Q6ZPE6
resolver
uniprot_sec
Q8BRF0
resolver
uniprot_sec
Q8BS51
resolver
uniprot_sec
Q8C5E4
resolver
amino_acid_sequence
MGAPGLRAATAALGLLLCAGLGRAGPAGSGGHGAPGQLLDDDAQRPCPAACHCLGDLLDCSRRRLVRLPDPLPAWVTRLDLSHNRLSFIQTSSLSHLQSLQEVKLNNNELETIPNLGSISANIRQLSLAGNAIDKILPEQLEAFQSLETLDLSNNNISELRTAFPPLQLKYLYINNNRVSSMEPGYFDNLASTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEVLQLDHNNLTEITKGWLYGLLMLRELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNALHIGNNKVSYIADCAFRGLTSLKTLDLRNNEISWTIEDMSGAFSGLDRLRQLILQGNRIRSITKKAFAGLDTLEHLDLSGNAIMSLQSNAFSQMKKLQQLHLNTSSLLCDCQLRWLPQWVAENNFQSFVNASCAHPQLLKGRSIFTVSPDGFVCDDFPKPQITVQPETQSAIKGSDVSFTCSAASSSDSPMTFAWKKDNEALQDAEMENYAHLRAQGGELMEYTTILRLRNVEFTSEGKYQCVISNHFGSSYSVKAKLTINMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSVSANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPHMTAPSLDGDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYISSESGSHHQFVTSSGGGFFLPQHDGAGTCHFDDSSEADVEAASDPFLCPFVGSTGPVYLQGNLYSPDPFEVYLPGCSSDPRTALMDHCESSYVKQDRFSCARPSEEPCERSLKSIPWPHSRKLTDSTYPPNEGHTVQTLCLNKSSVDFSTGPEPGSATSSNSFMGTFGKPLRRPHLDAFSSSAQPPDCQPRPCHGKSLSSPELDSESEENDKERTDFREENHRCTYQQIFHTYRTPDCQPCDSDT
uniprot
proteins
function
FUNCTION: Plays a role in craniofacial and inner ear morphogenesis during embryonic development. Acts within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1. {ECO:0000269|PubMed:19004851, ECO:0000269|PubMed:20126551}.
uniprot
proteins
mass_dalton
122688
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15203213
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19004851
uniprot
proteins
pubmed
20126551
uniprot
proteins
sequence_length
1117
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20126551}; Single-pass type I membrane protein {ECO:0000269|PubMed:20126551}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:20126551}; Single-pass type I membrane protein {ECO:0000269|PubMed:20126551}. Note=Detected in cytoplasmic vesicles when coexpressed with ERBB4.
uniprot
proteins
transmembrane_region
TRANSMEM 810..830; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins