Hhip
entrez
15245
canonical
uniprot
Q7TN16
canonical
ensembl
ENSMUSG00000064325
resolver
ensp
ENSMUSP00000078047
resolver
enst
ENSMUST00000079038
resolver
genesymbol
Hhip
resolver
genesymbol_syn
Hip
resolver
uniprot
Q8C0B0
resolver
uniprot
Q9WU59
resolver
uniprot_entry
HHIP_MOUSE
resolver
uniprot_sec
Q8C0B0
resolver
uniprot_sec
Q9WU59
resolver
amino_acid_sequence
MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRVMSQLELLSGGEILCGGFYPRVSCCLQSDSPGLGRLENKIFSATNNSECSRLLEEIQCAPCSPHSQSLFYTPERDVLDGDLALPLLCKDYCKEFFYTCRGHIPGLLQTTADEFCFYYARKDAGLCFPDFPRKQVRGPASNYLGQMEDYEKVGGISRKHKHNCLCVQEVMSGLRQPVSAVHSGDGSHRLFILEKEGYVKILTPEGELFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLYVSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDVRTARVFLEVAELHRKHLGGQLLFGPDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQPPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGRDYESEPSLLEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGASSSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRVTVQPAQPLTSDCSRLCRNGYYTPTGKCCCSPGWEGDFCRIAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNVRRVTRAGILDQIIDMTSYLLDLTSYIV
uniprot
proteins
function
FUNCTION: Modulates hedgehog signaling in several cell types, including brain and lung through direct interaction with members of the hedgehog family. Soluble forms inhibit Shh-induced differentiation in the fibroblast cell line C3H/10T1/2.
uniprot
proteins
mass_dalton
78513
uniprot
proteins
protein_family
HHIP family
uniprot
proteins
pubmed
10050855
uniprot
proteins
pubmed
15019948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
700
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10050855}; Peripheral membrane protein {ECO:0000269|PubMed:10050855}. Secreted {ECO:0000269|PubMed:10050855}. Note=The last 22 C-terminal amino acids may participate in cell membrane attachment.
uniprot
proteins