B3gat1
entrez
76898
canonical
uniprot
Q9CW73
canonical
ensembl
ENSMUSG00000045994
resolver
ensp
ENSMUSP00000124067
resolver
ensp
ENSMUSP00000125700
resolver
ensp
ENSMUSP00000168625
resolver
genesymbol
B3gat1
resolver
uniprot
Q6PIG8
resolver
uniprot
Q8BXN8
resolver
uniprot
Q8R1V2
resolver
uniprot
Q8R531
resolver
uniprot_entry
B3GA1_MOUSE
resolver
uniprot_entry
Q8R1V2_MOUSE
resolver
uniprot_sec
Q6PIG8
resolver
uniprot_sec
Q8BXN8
resolver
uniprot_sec
Q8R531
resolver
amino_acid_sequence
MPKRRDILAIVLIVLPWTLLITVWHQSSLAPLLAVHKDEGSDPRHEAPPGADPREYCMSDRDIVEVVRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTARLLRDTGLNYTHLHVETPRNYKLRGDARDPRIPRGTMQRNLALRWLRETFPRNSTQPGVVYFADDDNTYSLELFEEMRSTRRVSVWPVAFVGGLRYEAPRVNGAGKVVGWKTVFDPHRPFAIDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPSVEI
uniprot
proteins
ec_number
2.4.1.135
uniprot
proteins
function
FUNCTION: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. {ECO:0000250|UniProtKB:O35789}.
uniprot
proteins
mass_dalton
38237
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.
uniprot
proteins
post_translational_modification
PTM: The soluble form derives from the membrane form by proteolytic processing. {ECO:0000250|UniProtKB:O35789}.
uniprot
proteins
protein_family
Glycosyltransferase 43 family
uniprot
proteins
pubmed
11872162
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
334
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Golgi apparatus membrane {ECO:0000250|UniProtKB:O35789}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O35789}. Secreted {ECO:0000250|UniProtKB:O35789}.; SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus membrane {ECO:0000250|UniProtKB:O35789}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O35789}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O35789}. Secreted {ECO:0000250|UniProtKB:O35789}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..27; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins