Srm
entrez
20810
canonical
uniprot
Q64674
canonical
ensembl
ENSMUSG00000006442
resolver
ensp
ENSMUSP00000006611
resolver
enst
ENSMUST00000006611
resolver
genesymbol
Srm
resolver
uniprot
Q543H0
resolver
uniprot_entry
Q543H0_MOUSE
resolver
uniprot_entry
SPEE_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: The activity is thought to be regulated mainly by the availability of decarboxylated S-adenosylmethionine.
uniprot
proteins
amino_acid_sequence
MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIEVSKKFLPGMAVGFSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVDYAYCSIPTYPSGQIGFMLCSKNPSTNFREPVQQLTQAQVEQMQLKYYNSDMHRAAFVLPEFTRKALNDIS
uniprot
proteins
ec_number
2.5.1.16
uniprot
proteins
function
FUNCTION: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33995
uniprot
proteins
pathway_participation
PATHWAY: Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.
uniprot
proteins
protein_family
Spermidine/spermine synthase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7803821
uniprot
proteins
sequence_length
302
uniprot
proteins