Hpn
entrez
29135
canonical
uniprot
Q05511
canonical
ensembl
ENSRNOG00000021097
resolver
ensp
ENSRNOP00000028644
resolver
ensp
ENSRNOP00000075632
resolver
ensp
ENSRNOP00000092304
resolver
enst
ENSRNOT00000079631
resolver
enst
ENSRNOT00000117697
resolver
genesymbol
Hpn
resolver
uniprot
A0A0G2KB31
resolver
uniprot
A0A8I6AHA6
resolver
uniprot_entry
A0A0G2KB31_RAT
resolver
uniprot_entry
A0A8I6AHA6_RAT
resolver
uniprot_entry
HEPS_RAT
resolver
amino_acid_sequence
MAKEGGRTAPCCSRPKVAALTVGTLLFLTGIGAASWAIVTILLRSDQEPLYQVQLSPGDSRLLVLDKTEGTWRLLCSSRSNARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGGLPLAQRLLDVISVCDCPRGRFLTATCQDCGRRKLPVDRIVGGQDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQAVVLQEARVPIISNEVCNSPDFYGNQIKPKMFCAGYPEGGIDACQGDSGGHFVCEDRISGTSRWRLCGIVSWGTGCALARKPGVYTKVIDFREWIFQAIKTHSEATGMVTQP
uniprot
proteins
ec_number
3.4.21.106
uniprot
proteins
function
FUNCTION: Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization. {ECO:0000250|UniProtKB:P05981}.
uniprot
proteins
mass_dalton
44926
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
17918732
uniprot
proteins
pubmed
8318546
uniprot
proteins
sequence_length
416
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P05981}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P05981}. Apical cell membrane {ECO:0000250|UniProtKB:P05981}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P05981}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins