Tnfsf15
entrez
252878
canonical
uniprot
Q8K3Y7
canonical
ensembl
ENSRNOG00000008930
resolver
ensp
ENSRNOP00000011845
resolver
ensp
ENSRNOP00000104629
resolver
enst
ENSRNOT00000011845
resolver
genesymbol
Tnfsf15
resolver
genesymbol_syn
Tl1
resolver
genesymbol_syn
Vegi
resolver
uniprot
A0A0H2UHG9
resolver
uniprot_entry
A0A0H2UHG9_RAT
resolver
uniprot_entry
TNF15_RAT
resolver
amino_acid_sequence
MAEELGLGFGEAVPVEMLPEGCRHRREARTGLAARSKACLALTCCLLSFPILAGLSTLLMTGQLRIPGKDCMFPTVTEERSAPSAQPVYTPSRDKPKAHLTIMRQTPVPHLKNELAALHWENNLGMAFTKNRMNYTNKFLVIPESGDYFIYSQITFRGTTSECGDISRVRRPKKPDSITVVITKVADSYPEPAHLLTGTKSVCEISSNWFQPIYLGAMFSLEEGDRLMVNVSDISLVDYTKEDKTFFGAFLI
uniprot
proteins
function
FUNCTION: Cytokine that signals through TNFRSF25 receptor. Functions as a T-cell costimulator, that increases IL-2 responsiveness and secretion of proinflammatory cytokines which enhances T-cell activation, proliferation and the survival of activated T-cells. Inhibits vascular endothelial growth and angiogenesis (in vitro). {ECO:0000250|UniProtKB:O95150}.
uniprot
proteins
mass_dalton
28029
uniprot
proteins
protein_family
Tumor necrosis factor family
uniprot
proteins
pubmed
11911831
uniprot
proteins
sequence_length
252
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:O95150}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O95150}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins