Ccdc85b
entrez
240514
canonical
uniprot
Q6PDY0
canonical
ensembl
ENSMUSG00000095098
resolver
ensp
ENSMUSP00000137537
resolver
ensp
ENSMUSP00000157571
resolver
enst
ENSMUST00000179549
resolver
enst
ENSMUST00000236881
resolver
genesymbol
Ccdc85b
resolver
genesymbol_syn
Dipa
resolver
uniprot
A0A494B9B6
resolver
uniprot_entry
A0A494B9B6_MOUSE
resolver
uniprot_entry
CC85B_MOUSE
resolver
amino_acid_sequence
MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPGGAVGSGAGPTPELALPPCGPRDLGDGSSSTGSVGSPDQLPLACSPDD
uniprot
proteins
function
FUNCTION: Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (PubMed:15644333, PubMed:22666460). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). {ECO:0000250|UniProtKB:A2CEM9, ECO:0000269|PubMed:15644333, ECO:0000269|PubMed:22666460}.
uniprot
proteins
mass_dalton
22133
uniprot
proteins
protein_family
CCDC85 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15644333
uniprot
proteins
pubmed
22666460
uniprot
proteins
pubmed
27404227
uniprot
proteins
sequence_length
202
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15644333, ECO:0000269|PubMed:22666460}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q15834}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q15834}.
uniprot
proteins