MTHFD2L
entrez
441024
canonical
uniprot
Q9H903
canonical
ensembl
ENSG00000163738
resolver
ensp
ENSP00000321984
resolver
ensp
ENSP00000557870
resolver
ensp
ENSP00000769836
resolver
ensp
ENSP00000795744
resolver
genesymbol
MTHFD2L
resolver
hgnc
HGNC:31865
resolver
uniprot
Q6P079
resolver
uniprot
Q8N560
resolver
uniprot_entry
MTD2L_HUMAN
resolver
uniprot_sec
Q6P079
resolver
uniprot_sec
Q8N560
resolver
amino_acid_sequence
MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSAFRGFRSSGVRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY
uniprot
proteins
ec_number
1.5.1.15
uniprot
proteins
ec_number
1.5.1.5
uniprot
proteins
ec_number
3.5.4.9
uniprot
proteins
function
FUNCTION: Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. {ECO:0000250|UniProtKB:D3ZUA0}.
uniprot
proteins
mass_dalton
37315
uniprot
proteins
pathway_participation
PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion. {ECO:0000250|UniProtKB:D3ZUA0}.
uniprot
proteins
protein_family
Tetrahydrofolate dehydrogenase/cyclohydrolase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
21163947
uniprot
proteins
sequence_length
347
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:D3ZUA0}; Peripheral membrane protein {ECO:0000250|UniProtKB:D3ZUA0}; Matrix side {ECO:0000250|UniProtKB:D3ZUA0}.
uniprot
proteins