Tbc1d4
entrez
210789
canonical
uniprot
Q8BYJ6
canonical
ensembl
ENSMUSG00000033083
resolver
ensp
ENSMUSP00000097913
resolver
ensp
ENSMUSP00000124511
resolver
ensp
ENSMUSP00000124909
resolver
ensp
ENSMUSP00000125509
resolver
ensp
ENSMUSP00000223995
resolver
ensp
ENSMUSP00000223996
resolver
ensp
ENSMUSP00000223997
resolver
ensp
ENSMUSP00000223998
resolver
enst
ENSMUST00000161991
resolver
enst
ENSMUST00000162617
resolver
genesymbol
Tbc1d4
resolver
genesymbol_syn
As160
resolver
genesymbol_syn
Kiaa0603
resolver
uniprot
E0CX53
resolver
uniprot
E9Q6Q8
resolver
uniprot
Q149C0
resolver
uniprot
Q149C1
resolver
uniprot
Q3T9E8
resolver
uniprot
Q3TAQ5
resolver
uniprot
Q5DU23
resolver
uniprot
Q66JU2
resolver
uniprot
Q6P2M2
resolver
uniprot
Q8BMH6
resolver
uniprot
Q8BXM2
resolver
uniprot_entry
E0CX53_MOUSE
resolver
uniprot_entry
E9Q6Q8_MOUSE
resolver
uniprot_entry
TBCD4_MOUSE
resolver
uniprot_sec
Q149C0
resolver
uniprot_sec
Q149C1
resolver
uniprot_sec
Q3T9E8
resolver
uniprot_sec
Q3TAQ5
resolver
uniprot_sec
Q5DU23
resolver
uniprot_sec
Q66JU2
resolver
uniprot_sec
Q6P2M2
resolver
uniprot_sec
Q8BMH6
resolver
uniprot_sec
Q8BXM2
resolver
amino_acid_sequence
MESPSCIQDEPFPHPLEPEPSAPAQPGATKPGDKRFRLWYVGGSCLDRRTTLPMLPWLMAEIRRRSQKPDAGGCGAPAAREVILVLSAPFLRCVPAPGAGVGGGAGSGAVQPNTGVFIFEHKAQHISRFIHNSHDLTYFAYLIKAQPDDPESQMACHVFRATDPNQVPDVISSIRQLSKAAMKEDSKPSKDNEDAFYNSQKFEVLYCGRVIVTHKKAPSSLIDDCKDKFSLHEQQRLKLQGERGGDPGDEMGVLEVESPVSPDDSLPEKADGTVNSPRALPSLASLPALASQPALASSRVCFPERILEDCGFDEQQEFRSRCSSVTGVMQKKVHENNQKTQPRRRHASAPSHVQPSDSEKNRTMLFQVGRFEINLISPDTKSVVLEKNFKDISSCSQGIKHVDHFGFICRESPEPGLSQYICYVFQCANESLVDEVMLTLKQAFSTAAALQSAKTQIKLCETCPMHSLHKLCERIEGLYPPRAKLVIQRHLSSLTDNEQADIFERVQKMKPISDQEENELVILHLRQLCEAKQRTHVHIGEGPAIISNSTIPENVTSGGRFKLDVLKNKAKRSLTSSLENIFSRGANRMRGRLGSMDSFERANSLASEKDFSPGDSPPGTPPASPLSSAWHAFPEEDSDSPQFRRRAHTFSHPPSSSRRKLNLQDGKAHGLRSPLLRQSSSEQCSIVPSARRMYKESNSSCSLPSLHTSFSAPSFTAPSFLKSFYQNSGRLSPQYENEIRQDTASESSDGEGRKRTSSTCSNESLNAGGTPVTPRRVSWRQRIFLRVASPVNKSPSAMQQQKDGLDRTELLPLSPLSPTMEEEPLIIFLSGDEDTEKVEEKKKSKELKSLWKKAIHQQILLLRMEKENQKLEEARRDELQSRKVKLDYEEVGTCQKEILIAWDKKLLNCRTKIRCDMEDIHTSLKEGVPKSRRGEIWQFLALQYRLRHRLPNKHQPPDTSYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGAGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRELYNHLEENEISPSLYAAPWFLTLFASQFPLGFVARVFDIIFLQGTEVIFKVALSLLSSQEALIMECENFENIVEFLKSTLPDMNTTEMEKIITQVFEMDISKQLHAYEVEYHVLQDELLESSYACEDNESLEKLERANNQLKRQNMDLLEKLQVAHAKIQALESNLETLLTRETKMKALIRTLEQDKMAYQKTVEQIRKLLPADALANCELLLKDLTHPTNDKAKAGNKP
uniprot
proteins
function
FUNCTION: May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
147451
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by AKT1; insulin-induced. Also phosphorylated by AMPK in response to insulin. Insulin-stimulated phosphorylation is required for SLC2A4/GLUT4 translocation. Has no effect on SLC2A4/GLUT4 internalization. {ECO:0000269|PubMed:11994271, ECO:0000269|PubMed:12637568, ECO:0000269|PubMed:16804075, ECO:0000269|PubMed:16804077}.
uniprot
proteins
pubmed
11994271
uniprot
proteins
pubmed
12637568
uniprot
proteins
pubmed
15254270
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16804075
uniprot
proteins
pubmed
16804077
uniprot
proteins
pubmed
18276765
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
1307
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11994271}. Note=Cytoplasmic perinuclear. {ECO:0000250}.
uniprot
proteins