Mrpl32
entrez
75398
canonical
uniprot
Q9DCI9
canonical
ensembl
ENSMUSG00000015672
resolver
ensp
ENSMUSP00000152345
resolver
enst
ENSMUST00000220621
resolver
genesymbol
Mrpl32
resolver
genesymbol_syn
Heg1
resolver
uniprot
Q91XR6
resolver
uniprot_entry
RM32_MOUSE
resolver
uniprot_sec
Q91XR6
resolver
amino_acid_sequence
MAPSLLLLSLPWPVRPGPLQRCWELLQRQLQQSWSRFVSPPWAPALAVQRPSILTELAHDTCENKENSSFLDSIFWMAAPKNRRTIEVNRCRRRNPQKLIKIKNNIDICPECGHLKQKHVLCGYCYEKVRQETTKIRQQIGAQEGGPFRAPSVETMVLYTGEKPSEKDQGKRIVERNIKRPSWFTQN
uniprot
proteins
function
FUNCTION: Component of the mitochondrial large ribosomal subunit (mt-LSU). The mitochondrial ribosome (mitoribosome) is a large ribonucleoprotein complex responsible for the synthesis of proteins inside mitochondria. {ECO:0000250|UniProtKB:Q9BYC8}.
uniprot
proteins
mass_dalton
21733
uniprot
proteins
post_translational_modification
PTM: MRPL32 precursor is processed by the m-AAA protease (composed of AFG3L2 and SPG7), which cleaves the N-terminal transit peptide (PubMed:16239145). Cleavage by the m-AAA protease takes place prior to assembly into the large subunit, an essential step for mitochondrial ribosome (mitoribosome) assembly (PubMed:16239145). Proper processing by the m-AAA protease is dependent on the zinc-binding region within the tightly folded C-terminal domain of MRPL32: zinc-dependent folding halts degradation initiated from the N-terminus and triggers the release of mature MRPL32 (By similarity). {ECO:0000250|UniProtKB:P25348, ECO:0000269|PubMed:16239145}.
uniprot
proteins
protein_family
Bacterial ribosomal protein bL32 family
uniprot
proteins
pubmed
11279069
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16239145
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
187
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9BYC8}.
uniprot
proteins