Kcnh7
entrez
170739
canonical
uniprot
O54852
canonical
ensembl
ENSRNOG00000007528
resolver
ensembl
ENSRNOG00055000680
resolver
ensembl
ENSRNOG00060009915
resolver
ensp
ENSRNOP00000009920
resolver
ensp
ENSRNOP00000072574
resolver
ensp
ENSRNOP00000078968
resolver
ensp
ENSRNOP00055000942
resolver
ensp
ENSRNOP00060013163
resolver
enst
ENSRNOT00000009920
resolver
enst
ENSRNOT00000085246
resolver
enst
ENSRNOT00000119314
resolver
enst
ENSRNOT00055001187
resolver
enst
ENSRNOT00060016841
resolver
genesymbol
Kcnh7
resolver
genesymbol_syn
Erg3
resolver
uniprot
A0A0G2K3B8
resolver
uniprot
A0A0H2UHF2
resolver
uniprot_entry
A0A0G2K3B8_RAT
resolver
uniprot_entry
A0A0H2UHF2_RAT
resolver
uniprot_entry
KCNH7_RAT
resolver
amino_acid_sequence
MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEDNAASPERVNPILPVKSVNRKLFGFKFPGLRVLTYRKQSLPQEDPDVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSQCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLTHSRSRESLCSIRRASSVHDIEGFNVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDVKTEKKNTSPPSSDKTIIAPKVKERTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAVHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGTQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKSQSINDSEGDTCKLRRRRLSFESEGDKDFSKENSANDADDSTDTIRRYQSSKKHFEEKKSRSSSFISSIDDEQKPLFLGTVDSTPRMVKASRHHGEEAAPPSGRIHTDKRSHSCKDITDTHSWEREHARAQPEECSPSGLQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQAILQLLQKQTTVVPPAYSMVTAGAEYQRPILRLLRTSHPRASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGKRLNTASEDNLTSLLKQDSDASSELDPRQRKSYLHPIRHPSLPDSSLSTVGILGLHRHVSDPGLPGK
uniprot
proteins
function
FUNCTION: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel (PubMed:11212207, PubMed:9390998). Exhibits faster activation and deactivation kinetics and slow inactivation at membrane potentials positive to 240 mV, resulting in the weakest inward rectification (PubMed:11212207, PubMed:9390998). {ECO:0000269|PubMed:11212207, ECO:0000269|PubMed:9390998}.
uniprot
proteins
mass_dalton
134901
uniprot
proteins
mutagenesis
MUTAGEN 480; /note="E->S: Lower channel activity."; /evidence="ECO:0000269|PubMed:11212207
uniprot
proteins
protein_family
H (Eag) (TC 1.A.1.20) subfamily
uniprot
proteins
protein_family
Kv11.3/KCNH7 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
10718922
uniprot
proteins
pubmed
11212207
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9390998
uniprot
proteins
sequence_length
1195
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q12809}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q12809}.
uniprot
proteins
transmembrane_region
TRANSMEM 413..433; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 450..470; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 495..515; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 522..542; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 550..570; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 642..662; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins