Trdn
entrez
59299
canonical
uniprot
Q9QX75
canonical
ensembl
ENSRNOG00000012609
resolver
ensp
ENSRNOP00000041570
resolver
enst
ENSRNOT00000042072
resolver
genesymbol
Trdn
resolver
uniprot
E9PTN7
resolver
uniprot
F1LY11
resolver
uniprot
Q5DVI6
resolver
uniprot
Q5DVI7
resolver
uniprot
Q9JKZ5
resolver
uniprot
Q9JKZ6
resolver
uniprot
Q9QX76
resolver
uniprot_entry
F1LY11_RAT
resolver
uniprot_entry
TRDN_RAT
resolver
uniprot_sec
E9PTN7
resolver
uniprot_sec
Q5DVI6
resolver
uniprot_sec
Q5DVI7
resolver
uniprot_sec
Q9JKZ5
resolver
uniprot_sec
Q9JKZ6
resolver
uniprot_sec
Q9QX76
resolver
amino_acid_sequence
MTEITAEGNASITTTVIDNKNGSVPKSPGKVLKRTVTEDIVTTFSSPAAWLLVIALIITWSAVAIVMFDLVDYKNFSASSIAKIGSDPLKLVNDAVEETTDWIYGFFSLLSDIISSDGDEDDEDADEDIDKGEIEEPPLKRKEIQKEKAEKQEKPEKKIQTKVSHREKEKGKEKLKGEKPEKKATHKEKLEKKERTETKMAAKEDKKIKTKEKTEEKAKKEMKVGKQEKAKPAAAKAKETPKTTPKAREKDDKETPAVPKHEQKDQYAFCRYMIDMFVHGDLKPGQSPAVPPPSLTASRPALSTPSLEEKEKEEKKKVEKKVTSDTKKKEKGEAKKKSEKETVIDGKGKEPGKPPETKQTTTKLTTQAAATKDEKKEDSKKMKKPPEEKPKGKKQEKKEKHIEPAKTPKKEHPAPSEKHRKAKAEQAKEEIAPASTKKALHGKKEEKAKTVEQGKDVKPKLPQPQLKKEEKSEPQPKKEVKLETQLKKEEKSEPQVKKEAKLASSEKGQTRKQNITRPEQVIPHGKPEQKVPKQIKAITAEKTEKAERQEKYHPSIKTEGKPEVTDSGKKKIEKPEKESKVPPKQENLQVRNVTRAEKRGKISKDSKDAPAPKKDKDSKDVLHSKKDKEVTNNVSSPKKQKSPISFFQCVYLDGYNGYGFQFPVTPVQHSGENPGKSNSPGQKQQEQ
uniprot
proteins
function
FUNCTION: Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. {ECO:0000250|UniProtKB:E9Q9K5}.
uniprot
proteins
mass_dalton
77200
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by CaMK2. {ECO:0000250|UniProtKB:Q28820}.; PTM: N-glycosylated. {ECO:0000269|PubMed:10713145}.
uniprot
proteins
pubmed
10713145
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15927957
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
687
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q28820}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q28820}. Microsome {ECO:0000269|PubMed:15927957}. Cell membrane, sarcolemma {ECO:0000269|PubMed:15927957}.
uniprot
proteins
transmembrane_region
TRANSMEM 48..68; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins