Spaca1
entrez
67652
canonical
uniprot
Q9DA48
canonical
ensembl
ENSMUSG00000028264
resolver
ensp
ENSMUSP00000029927
resolver
ensp
ENSMUSP00000081785
resolver
enst
ENSMUST00000029927
resolver
enst
ENSMUST00000084734
resolver
genesymbol
Spaca1
resolver
uniprot
B1AWF1
resolver
uniprot
B1AWF2
resolver
uniprot_entry
B1AWF1_MOUSE
resolver
uniprot_entry
B1AWF2_MOUSE
resolver
uniprot_entry
SACA1_MOUSE
resolver
amino_acid_sequence
MRARGAGCPAGLLAVGWLILVGLQASQASNVTSSGGGVQEPAVAREGESESESESEEEAENEGEVPESETTAEADAEEEVQNRTIVKEVEFGMCTVTCGVGIREVILTNGCPGGESKCVVRVEECRGPVDCGWGKPISENLDSARLSCVHISPENRFKYVWKLLKPDQQPVILTNDSAVLEITREIRPLAFECDTLDNNEMVASVKFTVYTTNELQMRRSSRPDTDAVLVFVLTIGVIICIFVIFVLIFIIINWAAVKSFWGSKTSATEIQSELSSMRYKDSTSLDQSPTDIPVHEDDALSEWNE
uniprot
proteins
function
FUNCTION: Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility. {ECO:0000269|PubMed:22949614}.
uniprot
proteins
mass_dalton
33343
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:22949614}.
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22949614
uniprot
proteins
pubmed
34231842
uniprot
proteins
pubmed
38573307
uniprot
proteins
sequence_length
305
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane {ECO:0000269|PubMed:22949614}; Single-pass type I membrane protein {ECO:0000305}. Note=Primarily found in the equatorial segment of the acrosome (PubMed:22949614). The tyrosine phosphorylated protein localizes to a smaller region within the equatorial segment (By similarity). Also expressed weakly in the principal segment (By similarity). {ECO:0000250|UniProtKB:D5K8A9, ECO:0000250|UniProtKB:Q9HBV2}.
uniprot
proteins
transmembrane_region
TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins