FITM1
entrez
161247
canonical
uniprot
A5D6W6
canonical
ensembl
ENSG00000139914
resolver
ensembl
ENSG00000285321
resolver
ensp
ENSP00000267426
resolver
genesymbol
FITM1
resolver
genesymbol_syn
FIT1
resolver
hgnc
HGNC:33714
resolver
uniprot
Q8IUQ7
resolver
uniprot_entry
FITM1_HUMAN
resolver
uniprot_sec
Q8IUQ7
resolver
amino_acid_sequence
MERGPVVGAGLGAGARIQALLGCLLKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVNPRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLATRRVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRRSCLAAGHQWRGYTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPLRLVFLLNVLLLGLWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGSPGHGLFPRPHSSRKHN
uniprot
proteins
function
FUNCTION: Plays an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity) (PubMed:18160536). Directly binds to diacylglycerol (DAGs) and triacylglycerol (By similarity). {ECO:0000255|HAMAP-Rule:MF_03229, ECO:0000269|PubMed:18160536}.
uniprot
proteins
mass_dalton
32207
uniprot
proteins
protein_family
FIT family
uniprot
proteins
protein_family
FIT1 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18160536
uniprot
proteins
sequence_length
292
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03229, ECO:0000269|PubMed:18160536}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03229}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 95..115; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 142..162; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 188..208; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 221..241; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 250..270; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins