Cct4
entrez
12464
canonical
uniprot
P80315
canonical
ensembl
ENSMUSG00000007739
resolver
ensp
ENSMUSP00000133523
resolver
enst
ENSMUST00000173867
resolver
genesymbol
Cct4
resolver
genesymbol_syn
Cctd
resolver
uniprot
Q564F4
resolver
uniprot_entry
Q564F4_MOUSE
resolver
uniprot_entry
TCPD_MOUSE
resolver
amino_acid_sequence
MPENVASRSGAPTAGPGSRGKSAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPVQLSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDVEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVSLNGSGKLFKITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGGISNILEEMVVQPLLVSVSALTLATETVRSILKIDDVVNTR
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
function
FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. {ECO:0000250|UniProtKB:P50991}.
uniprot
proteins
mass_dalton
58066
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
TCP-1 chaperonin family
uniprot
proteins
pubmed
10336634
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
23807208
uniprot
proteins
pubmed
23872636
uniprot
proteins
pubmed
7919332
uniprot
proteins
pubmed
7953530
uniprot
proteins
sequence_length
539
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23807208}. Melanosome {ECO:0000250|UniProtKB:P50991}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23807208}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:23807208}.
uniprot
proteins