Rnaseh1
entrez
298933
canonical
uniprot
Q5BK46
canonical
ensembl
ENSRNOG00000008584
resolver
ensembl
ENSRNOG00055005723
resolver
ensembl
ENSRNOG00060008941
resolver
ensembl
ENSRNOG00065010534
resolver
ensp
ENSRNOP00000011819
resolver
ensp
ENSRNOP00055007083
resolver
ensp
ENSRNOP00060011629
resolver
ensp
ENSRNOP00065013060
resolver
enst
ENSRNOT00000011819
resolver
enst
ENSRNOT00055009242
resolver
enst
ENSRNOT00060014991
resolver
enst
ENSRNOT00065017052
resolver
genesymbol
Rnaseh1
resolver
uniprot_entry
RNH1_RAT
resolver
activity_regulation
ACTIVITY REGULATION: In the presence of magnesium, manganese is inhibitory. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MRWLLPLFRTVTLAVVRVRRGVCGLGMFYAVRRGRRTGVFLSWSECKAQVDRFPAARFKKFATEDEAWAFVRSSSSPDGSKGQESAHVQKLQVKTSKRPREPLGEEEEPPEPGAKHTRQDTEPAALVSKDAFSYMGESVVVYTDGCCSSNGRKRARAGIGVYWGPGHPLNVGIRLPGRQTNQRAEIHAACKAITQAKAQNISKLVLYTDSMFTINGITNWVQGWKKNGWRTSTGKDVINKEDFMELDELTQGMDIQWMHIPGHSGFVGNEEADRLAREGAKQSEG
uniprot
proteins
ec_number
3.1.26.4
uniprot
proteins
function
FUNCTION: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. {ECO:0000250|UniProtKB:O60930}.
uniprot
proteins
mass_dalton
31773
uniprot
proteins
protein_family
RNase H family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
285
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins