Rbm33
entrez
381626
canonical
uniprot
Q9CXK9
canonical
ensembl
ENSMUSG00000048271
resolver
ensp
ENSMUSP00000062449
resolver
ensp
ENSMUSP00000110534
resolver
ensp
ENSMUSP00000328521
resolver
enst
ENSMUST00000114884
resolver
genesymbol
Rbm33
resolver
genesymbol_syn
Prr8
resolver
uniprot
D3Z5I9
resolver
uniprot
Q3U5Z3
resolver
uniprot
Q8C5J6
resolver
uniprot_entry
D3Z5I9_MOUSE
resolver
uniprot_entry
RBM33_MOUSE
resolver
uniprot_sec
Q3U5Z3
resolver
uniprot_sec
Q8C5J6
resolver
amino_acid_sequence
MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEEEENFSSQGVTISLNTTSGIVTSFELSDNTNDQSGEQESEYEQGDDELAYHKPEEQELYTQEYPEEGQYEGHDAELTEDQIEYGDEPEEEQLYSDEVLDIEINEPLDEFTDEEYLQAYGGQQGLQVREDCEAEDDLDEITDSQVASETHEGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYGSRRGGRRGGSLMCRGMGDQRRDNSERGRMKEHRPALLPTQPSVVAHSPRLIPPPQPQPPPPPPPPPPQQQPIRSLFQQQQLQPLLPLQHPHHPSPPQGVHMPPQIETPRMMLTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFNQPPRLPLQDQWRAPPPPQERDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATARPFIPPRQPFLPSPGQPFLPTHAQPNLQGPLHPPLPPPHQPQPQPQQPQQQPQHHQHQPPLQPPLQPPHQPPPQHQPPPQHQPQQHQHHHHLSAPPPPLMPMSQPQFRPHVQTAQPQPSSSRMQCTPHQGLRHNAASQNISKRPMQQMQPTAPRNSNLRELPIAPSHVLEMSGNRCSSTPVAQVKSIVNTSPPCRAVVSSRSSQGNTDAKAKPLSPEAQPKEEAKPEAEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQQQQQQHQPQQQQQQPQQIYGSQTSMEQEELAATPSPTNGNPLLPFPGAQCRQNVKTRLLVKNQDITTASVQPKAVNFVPPGANVQHQGQHLRPLKHLRQLPHKVLQVKPMDMEETPHSPQAARVTSLQGRPQDTKPGVKRTVMHRANSGGGGDGPHVSSKVRVIKLSGGQGGESDGFSHTEGQPQRLPQPPDMRQQPTRKVTLTKGVPQQPQHLPVGPHMYPAIPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDVQLKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMIDLSHINVALIVE
uniprot
proteins
function
FUNCTION: RNA reader protein, which recognizes and binds specific RNAs, thereby regulating RNA metabolic processes, such as mRNA export, mRNA stability and/or translation. Binds a subset of intronless RNAs containing GC-rich elements, such as NORAD, and promotes their nuclear export by recruiting target RNAs to components of the NXF1-NXT1 RNA export machinery. Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, promoting their demethylation by ALKBH5. Acts as an molecular adapter, which (1) promotes ALKBH5 recruitment to m6A-containing transcripts and (2) activates ALKBH5 demethylase activity by recruiting SENP1, leading to ALKBH5 deSUMOylation and subsequent activation. {ECO:0000250|UniProtKB:Q96EV2}.
uniprot
proteins
mass_dalton
137325
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
1231
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q96EV2}. Cytoplasm {ECO:0000250|UniProtKB:Q96EV2}. Note=Localizes predominantly to the nucleus. {ECO:0000250|UniProtKB:Q96EV2}.
uniprot
proteins