Kcne4
entrez
57814
canonical
uniprot
Q9WTW3
canonical
ensembl
ENSMUSG00000047330
resolver
ensp
ENSMUSP00000055415
resolver
enst
ENSMUST00000057262
resolver
genesymbol
Kcne4
resolver
uniprot_entry
KCNE4_MOUSE
resolver
amino_acid_sequence
MLRMEPLNSTYPSAAASSSPLESHVPSNSSGNGNEYFYILVVMSFYGVFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPMMSGLRSGQVPMMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLPIQEEGADDELEETSETPLNDSSEGSSENIHQNS
uniprot
proteins
function
FUNCTION: Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. {ECO:0000250|UniProtKB:Q8WWG9}.
uniprot
proteins
mass_dalton
18639
uniprot
proteins
protein_family
Potassium channel KCNE family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19773357
uniprot
proteins
pubmed
27802162
uniprot
proteins
pubmed
32370164
uniprot
proteins
sequence_length
170
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q8WWG9}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..56; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins