GTPBP4
entrez
23560
canonical
uniprot
Q9BZE4
canonical
ensembl
ENSG00000107937
resolver
ensp
ENSP00000354040
resolver
genesymbol
GTPBP4
resolver
genesymbol_syn
CRFG
resolver
genesymbol_syn
NOG1
resolver
hgnc
HGNC:21535
resolver
uniprot
B3KMC5
resolver
uniprot
B4DY13
resolver
uniprot
B7Z7A3
resolver
uniprot
O95446
resolver
uniprot
Q5T3R8
resolver
uniprot
Q9NVJ8
resolver
uniprot_entry
GTPB4_HUMAN
resolver
uniprot_sec
B3KMC5
resolver
uniprot_sec
B4DY13
resolver
uniprot_sec
B7Z7A3
resolver
uniprot_sec
O95446
resolver
uniprot_sec
Q5T3R8
resolver
uniprot_sec
Q9NVJ8
resolver
amino_acid_sequence
MAHYNFKKITVVPSAKDFIDLTLSKTQRKTPTVIHKHYQIHRIRHFYMRKVKFTQQNYHDRLSQILTDFPKLDDIHPFYADLMNILYDKDHYKLALGQINIAKNLVDNVAKDYVRLMKYGDSLYRCKQLKRAALGRMCTVIKRQKQSLEYLEQVRQHLSRLPTIDPNTRTLLLCGYPNVGKSSFINKVTRADVDVQPYAFTTKSLFVGHMDYKYLRWQVVDTPGILDHPLEDRNTIEMQAITALAHLRAAVLYVMDLSEQCGHGLREQLELFQNIRPLFINKPLIVVANKCDVKRIAELSEDDQKIFTDLQSEGFPVIETSTLTEEGVIKVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAIPTRRDDKERPPFIPEGVVARRKRMETEESRKKRERDLELEMGDDYILDLQKYWDLMNLSEKHDKIPEIWEGHNIADYIDPAIMKKLEELEKEEELRTAAGEYDSVSESEDEEMLEIRQLAKQIREKKKLKILESKEKNTQGPRMPRTAKKVQRTVLEKEMRSLGVDMDDKDDAHYAVQARRSRSITRKRKREDSAPPSSVARSGSCSRTPRDVSGLRDVKMVKKAKTMMKNAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR
uniprot
proteins
function
FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit (PubMed:32669547). Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest (PubMed:20308539). {ECO:0000269|PubMed:20308539, ECO:0000269|PubMed:32669547}.
uniprot
proteins
mass_dalton
73964
uniprot
proteins
protein_family
NOG subfamily
uniprot
proteins
protein_family
OBG GTPase family
uniprot
proteins
protein_family
TRAFAC class OBG-HflX-like GTPase superfamily
uniprot
proteins
pubmed
11316846
uniprot
proteins
pubmed
12429849
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20308539
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
32669547
uniprot
proteins
pubmed
35393574
uniprot
proteins
sequence_length
634
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:11316846, ECO:0000269|PubMed:12429849, ECO:0000269|Ref.8}.
uniprot
proteins