CDKN2B
entrez
1030
canonical
uniprot
P42772
canonical
ensembl
ENSG00000147883
resolver
ensp
ENSP00000276925
resolver
ensp
ENSP00000369487
resolver
genesymbol
CDKN2B
resolver
genesymbol_syn
MTS2
resolver
hgnc
HGNC:1788
resolver
uniprot
K7PPU3
resolver
uniprot
O15125
resolver
uniprot
Q6FI09
resolver
uniprot_entry
CDN2B_HUMAN
resolver
uniprot_entry
K7PPU3_HUMAN
resolver
uniprot_sec
O15125
resolver
uniprot_sec
Q6FI09
resolver
amino_acid_sequence
MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEERGHRDVAGYLRTATGD
uniprot
proteins
function
FUNCTION: Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
uniprot
proteins
mass_dalton
14722
uniprot
proteins
protein_family
CDKN2 cyclin-dependent kinase inhibitor family
uniprot
proteins
pubmed
10892805
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7882351
uniprot
proteins
pubmed
8001816
uniprot
proteins
pubmed
8078588
uniprot
proteins
pubmed
8153634
uniprot
proteins
pubmed
9230210
uniprot
proteins
sequence_length
138
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:9230210}. Note=Also found in the nucleus.
uniprot
proteins