Ano7
entrez
367318
canonical
uniprot
Q6IFT6
canonical
ensembl
ENSRNOG00000023427
resolver
ensembl
ENSRNOG00060009030
resolver
ensp
ENSRNOP00000033330
resolver
ensp
ENSRNOP00060011771
resolver
enst
ENSRNOT00000033233
resolver
enst
ENSRNOT00060015146
resolver
genesymbol
Ano7
resolver
genesymbol_syn
Ngep
resolver
genesymbol_syn
Tmem16g
resolver
uniprot_entry
ANO7_RAT
resolver
amino_acid_sequence
MLRKQAGEEDSVVLIDMTSPEAGNGCSYGSTAQASEAGKQQVAPSRVGSSANPPIDFVLVWEEDLRSRENPTQDKTDTHEIWRETFLENLRVAGLKIDQRDVQDEAAAVHYILLSAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLENVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHQKKGLFGIDQLLAEGVFSAAFPLHDGPFSVVPESSQVLGLTQRQVLFKHWARWGKWRKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLAGCFLVFSDVPTQELCHSSDTFDMCPLCSDCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSIILYRAVMAIIVSKSNNAFLSAWASRIASLTGSVVNLVFILILSKVYVILAQVLTRWEMHRTQTAFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGVRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKLCSRRKKAGMGANPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRVYYSWTRAPDLRGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSTGRFLDLLVPDIPESVEIKVKREYYLAKQALADNEALLGATGVKGEQPPSSEPSLGLPA
uniprot
proteins
function
FUNCTION: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). May play a role in cell-cell interactions (By similarity). {ECO:0000250|UniProtKB:Q14AT5, ECO:0000250|UniProtKB:Q6IWH7}.
uniprot
proteins
mass_dalton
97170
uniprot
proteins
protein_family
Anoctamin family
uniprot
proteins
pubmed
14981236
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
860
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q6IWH7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q6IWH7}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q6IWH7}. Note=Concentrates at sites of cell-cell contact. Shows an intracellular localization. {ECO:0000250|UniProtKB:Q6IWH7}.
uniprot
proteins
transmembrane_region
TRANSMEM 298..318; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 363..383; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 442..462; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 493..513; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 531..551; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 653..673; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 702..722; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 780..800; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins