Slc6a11
entrez
79213
canonical
uniprot
P31647
canonical
ensembl
ENSRNOG00000005697
resolver
ensembl
ENSRNOG00055008132
resolver
ensembl
ENSRNOG00060012908
resolver
ensembl
ENSRNOG00065028538
resolver
ensp
ENSRNOP00000008342
resolver
ensp
ENSRNOP00055011042
resolver
ensp
ENSRNOP00060017380
resolver
ensp
ENSRNOP00065040353
resolver
enst
ENSRNOT00000008342
resolver
enst
ENSRNOT00055013751
resolver
enst
ENSRNOT00060021963
resolver
enst
ENSRNOT00065049209
resolver
genesymbol
Slc6a11
resolver
genesymbol_syn
Gabt3
resolver
genesymbol_syn
Gat-3
resolver
genesymbol_syn
Gat-b
resolver
uniprot_entry
S6A11_RAT
resolver
activity_regulation
ACTIVITY REGULATION: GABA transport is inhibited by beta-alanine. {ECO:0000269|PubMed:1400419, ECO:0000269|PubMed:1497897}.
uniprot
proteins
amino_acid_sequence
MTAEQALPLGNGKAAEEARGSEALGGGGGGAAGTREARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIVSYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWLMALSSMLCIPLWIFIKLWKTEGTLPEKLQKLTVPSADLKMRGKLGASPRMVTVNDCEAKVKGDGTISAITEKETHF
uniprot
proteins
function
FUNCTION: Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:1400419, PubMed:1497897). Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity). {ECO:0000250|UniProtKB:P31650, ECO:0000269|PubMed:1400419, ECO:0000269|PubMed:1497897}.
uniprot
proteins
mass_dalton
69947
uniprot
proteins
protein_family
SLC6A11 subfamily
uniprot
proteins
protein_family
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family
uniprot
proteins
pubmed
1400419
uniprot
proteins
pubmed
1497897
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8731228
uniprot
proteins
sequence_length
627
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:8731228}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 54..74; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 82..101; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 126..146; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 221..239; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 248..265; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 301..318; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 330..351; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 384..403; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 433..451; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 468..488; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 509..528; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 548..566; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins