Gon4l
entrez
76022
canonical
uniprot
Q9DB00
canonical
ensembl
ENSMUSG00000054199
resolver
ensp
ENSMUSP00000080397
resolver
ensp
ENSMUSP00000103122
resolver
ensp
ENSMUSP00000312579
resolver
ensp
ENSMUSP00000312580
resolver
enst
ENSMUST00000081695
resolver
enst
ENSMUST00000107498
resolver
genesymbol
Gon4l
resolver
genesymbol_syn
5830417I10Rik
resolver
genesymbol_syn
Gon4
resolver
genesymbol_syn
Kiaa1606
resolver
uniprot
E9Q507
resolver
uniprot
E9Q5N3
resolver
uniprot
F8WGY9
resolver
uniprot
Q32NZ8
resolver
uniprot
Q80TB4
resolver
uniprot
Q91YI9
resolver
uniprot_entry
E9Q507_MOUSE
resolver
uniprot_entry
GON4L_MOUSE
resolver
uniprot_entry
Q32NZ8_MOUSE
resolver
uniprot_sec
E9Q5N3
resolver
uniprot_sec
F8WGY9
resolver
uniprot_sec
Q80TB4
resolver
uniprot_sec
Q91YI9
resolver
amino_acid_sequence
MLPCKKRRLSVTESSQQQDDQEGDDLDLEAAVKPDTDQLPDSASESLSWGQSQDSAVCPEGLSMQDGDDQLRAEGLSLNSKMLAQHVNLAVLEAVDVAVSQEIPLPSLESSHSLPVHVDKGRLQVSASKKGKRVVFTPGQVTREDRGDHPVPEEPPSGEPAEEAKTEGGELELRSDGEVPLLSSSSQSAKPGAQPRKSVQPDGSAFPQDKPLGPLVRQAEEEMEDGGLFIPTEEQDSEESDKKKKTKKGTKRKRDGKGPEQGTMVYDPKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPLFEPKMTRSKLKEVVEKGVVIPTWNISPIKKASEIKQPPQFVDIHLEEDDSSDEEYSPDEEEEDETAEESLLESDVESTASSPRGVKRSRLRLSSEVAETDEESGMLSEVEKAATPALRHISAEVVPMGPPPPPKPKQSRDSVFMEKLDAVDEELASSPVCMDSFQPMEDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKQWLGGLINDDVENEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNGLMEELFETVQSVVPSKFQDEMGFSNMEDDGPEEEERATESRPSFNTPQALRFEEPLANLLNERHRTVKELLEQLKMKKPSVRQQPEVEKLKPQEEAAHQTLVLDPAQRSRLQQQMQQHVQLLTQIYLLTTSNPNLSSEASTTRIFLKELGTFAENSIALHQQFNPRFQTLFQPCNWMGAMRLIEDFTQVSIDCSPHKTAKKTASEFPCLPKQVAWILATNKVFMYPELLPICSLKANNPRDKTIFTKAEDNLLALGLKHFEGTEFPKPLISKYLVTCKTAHQLTVRIKNLNLNRAPNNVIKFYKKTKQLPVLVRCCEEIQPHQWKPPFEKEEHRLPFWLKASLQSIQDELRNISEGATEGGSVTTATESSTDQHLQKASPALGDEPQYPLLLPKGVVLKLKPGSKRFSRKAWRQKRPLVQKPLLIQPSPSVQPVFNPGKMATWPTQSEVPPSNTVVQIPHLIQPAAVLQTLPGFPSVGVRGEDGFESPTALPAMPCGSEARTTFPLSETQSAPPSCSAPKLMLPSLAPSKFRKPYVRRKPTRRKGAKVSPCVKPAPIIHPTPVIFTVPATTVKVVSIGGGCNMIQPVSAAVAPSPQTIPITTLLVNPTTFPCSLNQPLVASSISPLIVSSNPLTLPVTSIPEDKAQVKLDVAEGKNAPQNPESKLKPQELTPLCTTVFSKEEPKSWHSSADTGSQEAFSESSACSWAVVKTESQEGSSEKSACGWTVVKTEDGGHAVEPLPQNLQDSLSSSSKDLLNMVKMEAQDCMVEISSNFPKQDIGEEVKEECSMELDSESPQEKPSSASEMSKQTVLQREDMQAAKSPSVPQDAAAEGRTSSHASRGLPKSTLSSMGQGGGLSGPPGKLEDSANADGQSVGTPAGPDTGGEKDGPEEEEEEDFDDLTQDEEDELSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMETLQKEDEVNDEAVGDAAKKPPSTLASPQTAPEIETSIAPAGESIKAAGKGRSSHRARNKRGSRARASKDTSKLLLLYDEDILDRDPLREQKDLAFAQAYLTRVREALQHTPGKYEDFLQIIYEFESSTQMHSAVDLFKSLQTLLQDWPQLLKDFAAFLLPEQALSCGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQDIAELKTQMWQLLRGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVILPDVEEDEEPAKVSTASKSKRRKEIGVQHQDKDTEWPEAAKDCSCSCHEGGPESKLKKSKRRNCHCSSKVCDSKPYKSKEPPELVGSGPLHEASTVPGSKEAGQGKDMLEEEILEEQENMEVTQSKTARTTRKGEAPAPGSTIGSTLLCPAEVTPMELLLEGPALCSAETPRLPPQTGAVVCSVRRNQAGPEVVSCLSTSSLPPEEGEDQRAAANSETIAPHREASETERLPETVEHSAPLPSPVSTRTRDTGRRHICGKAGSQSWLIESRAEAEAAHVAAPICEKSSGARASEAAPKTAREVLAEDSGTQGMGPEGALPKASEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPHTFSVISQQLGNKTPVEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE
uniprot
proteins
function
FUNCTION: Acts as a key transcription regulator of histones (By similarity). Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with GON4L and MIZF. Together with CRAMP1, binds to the promoters of H1 genes (H1-2, H1-3, H1-4, H1-5 and H1-10/H1x), driving their transcription (By similarity). Also acts as a transcription corepressor, as part of a complex with YY1, SIN3A and HDAC1 (PubMed:21454521). Required for B-cell lymphopoiesis (PubMed:20530203). {ECO:0000250|UniProtKB:Q3T8J9, ECO:0000269|PubMed:20530203, ECO:0000269|PubMed:21454521}.
uniprot
proteins
mass_dalton
248742
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20530203
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21454521
uniprot
proteins
sequence_length
2260
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00810, ECO:0000269|PubMed:21454521}. Chromosome {ECO:0000250|UniProtKB:Q3T8J9}. Note=Localizes to histone locus bodies (HLB). {ECO:0000250|UniProtKB:Q3T8J9}.
uniprot
proteins