AK3
entrez
50808
canonical
uniprot
Q9UIJ7
canonical
ensembl
ENSG00000147853
resolver
ensp
ENSP00000352948
resolver
ensp
ENSP00000371230
resolver
ensp
ENSP00000413933
resolver
ensp
ENSP00000482308
resolver
genesymbol
AK3
resolver
genesymbol_syn
AK3L1
resolver
genesymbol_syn
AK6
resolver
genesymbol_syn
AKL3L
resolver
hgnc
HGNC:17376
resolver
uniprot
B4DP58
resolver
uniprot
D3DRI1
resolver
uniprot
E7ET30
resolver
uniprot
Q5VYW6
resolver
uniprot
Q7Z4Y4
resolver
uniprot
Q9H576
resolver
uniprot
Q9HC01
resolver
uniprot
Q9NPB4
resolver
uniprot_entry
KAD3_HUMAN
resolver
uniprot_entry
Q7Z4Y4_HUMAN
resolver
uniprot_sec
B4DP58
resolver
uniprot_sec
D3DRI1
resolver
uniprot_sec
E7ET30
resolver
uniprot_sec
Q5VYW6
resolver
uniprot_sec
Q9H576
resolver
uniprot_sec
Q9HC01
resolver
uniprot_sec
Q9NPB4
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by ATP. {ECO:0000269|PubMed:32822537}.
uniprot
proteins
amino_acid_sequence
MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
uniprot
proteins
ec_number
2.7.4.10
uniprot
proteins
function
FUNCTION: Mitochondrial adenylate kinase with a specific GTP:AMP phosphotransferase activity (PubMed:11485571, PubMed:32822537). Could also use ITP as phosphate donor (PubMed:11485571). Its physiological function is to recycle GTP into GDP which is necessary for the TCA cycle in the mitochondrial matrix (Probable). {ECO:0000269|PubMed:11485571, ECO:0000269|PubMed:32822537, ECO:0000305|PubMed:11485571, ECO:0000305|PubMed:35457131}.
uniprot
proteins
mass_dalton
25565
uniprot
proteins
protein_family
AK3 subfamily
uniprot
proteins
protein_family
Adenylate kinase family
uniprot
proteins
pubmed
11485571
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
32822537
uniprot
proteins
pubmed
35457131
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|PubMed:11485571}.
uniprot
proteins