Apba1
entrez
83589
canonical
uniprot
O35430
canonical
ensembl
ENSRNOG00000014928
resolver
ensembl
ENSRNOG00055031190
resolver
ensembl
ENSRNOG00060021137
resolver
ensembl
ENSRNOG00065024825
resolver
ensp
ENSRNOP00000020123
resolver
ensp
ENSRNOP00000089303
resolver
enst
ENSRNOT00000020123
resolver
genesymbol
Apba1
resolver
genesymbol_syn
Mint1
resolver
genesymbol_syn
X11
resolver
uniprot
F1LR60
resolver
uniprot_entry
APBA1_RAT
resolver
uniprot_entry
F1LR60_RAT
resolver
amino_acid_sequence
MNHLEGSAEVEVADEAPGGEVNESVEADLEHPEVEEEQQPSPPPPAGHAPEDHRAHPAPPPPPPPQEEEEERGECLARSASTESGFHNHTDTAEGDVLAAARDGYEAERAQDADDESAYAVQYRPEAEEYTEQAEAEHAEAAQRRALPNHLHFHSLEHEEAMNAAYSGYVYTHRLFHRAEDEPYAEPYADYGGLQEHVYEEIGDAPELEARDGLRLYERERDEAAAYRQEALGARLHHYDERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQDLERAPTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSSPLGAESSITPLHPGDPTEASTNKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHPSQDAKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI
uniprot
proteins
function
FUNCTION: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta.
uniprot
proteins
mass_dalton
92654
uniprot
proteins
mutagenesis
MUTAGEN 633; /note="Y->E: Enhanced APP binding and amyloid-beta production."; /evidence="ECO:0000269|PubMed:22355143"; MUTAGEN 633; /note="Y->F: No change in APP binding."; /evidence="ECO:0000269|PubMed:22355143
uniprot
proteins
pubmed
20531236
uniprot
proteins
pubmed
22355143
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9395480
uniprot
proteins
pubmed
9753324
uniprot
proteins
sequence_length
839
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20531236}. Note=Only a small proportion of the protein is nuclear.; SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus {ECO:0000250}.
uniprot
proteins