Adipor2
entrez
68465
canonical
uniprot
Q8BQS5
canonical
ensembl
ENSMUSG00000030168
resolver
ensp
ENSMUSP00000032272
resolver
ensp
ENSMUSP00000126138
resolver
ensp
ENSMUSP00000286041
resolver
genesymbol
Adipor2
resolver
genesymbol_syn
D6Ucla1e
resolver
genesymbol_syn
Paqr2
resolver
genesymbol_syn
Parq2
resolver
uniprot
Q53YY3
resolver
uniprot
Q8CA45
resolver
uniprot
Q8CID6
resolver
uniprot_entry
PAQR2_MOUSE
resolver
uniprot_entry
Q53YY3_MOUSE
resolver
uniprot_sec
Q8CA45
resolver
uniprot_sec
Q8CID6
resolver
amino_acid_sequence
MNEPAKHRLGCTRTPEPDIRLRKGHQLDDTRGSNNDNYQGDLEPSLETPVCSSYYENSPEEPECHDDNSQEDEGFMGMSPLLQAHHAMERMEEFVCKVWEGRWRVIPHDVLPDWLKDNDFLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGCVFFLCLGIFYMFRPNISFVAPLQEKVVFGLFFLGAILCLSFSWLFHTVYCHSEGVSRLFSKLDYSGIALLIMGSFVPWLYYSFYCNPQPCFIYLIVICVLGIAAIIVSQWDMFATPQYRGVRAGVFVGLGLSGIIPTLHYVISEGFLKAATIGQIGWLMLMASLYITGAALYAARIPERFFPGKCDIWFHSHQLFHIFVVAGAFVHFHGVSNLQEFRFMIGGGCTEEDAL
uniprot
proteins
function
FUNCTION: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:17068142, PubMed:17268472, PubMed:17327425, PubMed:24742672). Required for normal body fat and glucose homeostasis (PubMed:17068142, PubMed:17268472, PubMed:17327425, PubMed:24742672). ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake (PubMed:12802337, PubMed:17268472, PubMed:24742672). Has intermediate affinity for globular and full-length adiponectin (PubMed:12802337). Required for normal revascularization after chronic ischemia caused by severing of blood vessels (PubMed:24742672). {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:17068142, ECO:0000269|PubMed:17268472, ECO:0000269|PubMed:17327425, ECO:0000269|PubMed:24742672}.
uniprot
proteins
mass_dalton
43981
uniprot
proteins
protein_family
ADIPOR family
uniprot
proteins
pubmed
12802337
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17068142
uniprot
proteins
pubmed
17268472
uniprot
proteins
pubmed
17327425
uniprot
proteins
pubmed
19661063
uniprot
proteins
pubmed
24742672
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q86V24}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q86V24}. Note=Localized to the cell membrane and intracellular organelles. {ECO:0000250|UniProtKB:Q86V24}.
uniprot
proteins
transmembrane_region
TRANSMEM 148..168; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q86V24"; TRANSMEM 182..202; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q86V24"; TRANSMEM 214..234; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q86V24"; TRANSMEM 246..266; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q86V24"; TRANSMEM 274..294; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q86V24"; TRANSMEM 310..330; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q86V24"; TRANSMEM 349..369; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q86V24
uniprot
proteins