GPLD1
entrez
2822
canonical
uniprot
P80108
canonical
ensembl
ENSG00000112293
resolver
ensp
ENSP00000230036
resolver
ensp
ENSP00000647416
resolver
genesymbol
GPLD1
resolver
genesymbol_syn
PIGPLD1
resolver
hgnc
HGNC:4459
resolver
uniprot
Q15127
resolver
uniprot
Q15128
resolver
uniprot
Q2M2F2
resolver
uniprot
Q5T3Y0
resolver
uniprot
Q7Z6T8
resolver
uniprot
Q8TCV0
resolver
uniprot
Q8WW82
resolver
uniprot
Q96ID6
resolver
uniprot
Q9H167
resolver
uniprot
Q9H4M1
resolver
uniprot
Q9UJC9
resolver
uniprot_entry
PHLD_HUMAN
resolver
uniprot_sec
Q15127
resolver
uniprot_sec
Q15128
resolver
uniprot_sec
Q2M2F2
resolver
uniprot_sec
Q5T3Y0
resolver
uniprot_sec
Q7Z6T8
resolver
uniprot_sec
Q8TCV0
resolver
uniprot_sec
Q8WW82
resolver
uniprot_sec
Q96ID6
resolver
uniprot_sec
Q9H167
resolver
uniprot_sec
Q9H4M1
resolver
uniprot_sec
Q9UJC9
resolver
amino_acid_sequence
MSAFRLWPGLLIMLGSLCHRGSPCGLSTHVEIGHRALEFLQLHNGRVNYRELLLEHQDAYQAGIVFPDCFYPSICKGGKFHDVSESTHWTPFLNASVHYIRENYPLPWEKDTEKLVAFLFGITSHMAADVSWHSLGLEQGFLRTMGAIDFHGSYSEAHSAGDFGGDVLSQFEFNFNYLARRWYVPVKDLLGIYEKLYGRKVITENVIVDCSHIQFLEMYGEMLAVSKLYPTYSTKSPFLVEQFQEYFLGGLDDMAFWSTNIYHLTSFMLENGTSDCNLPENPLFIACGGQQNHTQGSKMQKNDFHRNLTTSLTESVDRNINYTERGVFFSVNSWTPDSMSFIYKALERNIRTMFIGGSQLSQKHVSSPLASYFLSFPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHGVTVDNRTLLLVGSPTWKNASRLGHLLHIRDEKKSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLTVTLHQGGATRMYALTSDAQPLLLSTFSGDRRFSRFGGVLHLSDLDDDGLDEIIMAAPLRIADVTSGLIGGEDGRVYVYNGKETTLGDMTGKCKSWITPCPEEKAQYVLISPEASSRFGSSLITVRSKAKNQVVIAAGRSSLGARLSGALHVYSLGSD
uniprot
proteins
ec_number
3.1.4.50
uniprot
proteins
function
FUNCTION: Hydrolyzes the inositol phosphate linkage of glycosylphosphatidylinositol (GPI)-anchored membrane proteins, thereby releasing them from the cell surface. Cleaves on the inositol side of the anchor, leaving the phosphate group attached to the membrane (PubMed:17720976, PubMed:2760042). This release of GPI-anchored proteins can modulate diverse biological processes, including the activation of signaling pathways (PubMed:17720976). {ECO:0000269|PubMed:17720976, ECO:0000269|PubMed:2760042}.
uniprot
proteins
mass_dalton
92336
uniprot
proteins
protein_family
GPLD1 family
uniprot
proteins
pubmed
11072085
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1606959
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
17720976
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
2760042
uniprot
proteins
sequence_length
840
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:2760042}. Note=Associated with the High-Density Lipoproteins (HDL). {ECO:0000250|UniProtKB:P80109}.
uniprot
proteins