Tmprss11e
entrez
243084
canonical
uniprot
Q5S248
canonical
ensembl
ENSMUSG00000054537
resolver
ensp
ENSMUSP00000124534
resolver
enst
ENSMUST00000161306
resolver
genesymbol
Tmprss11e
resolver
genesymbol_syn
Desc1
resolver
uniprot
A4FUP5
resolver
uniprot
Q8BM10
resolver
uniprot_entry
TM11E_MOUSE
resolver
uniprot_sec
A4FUP5
resolver
uniprot_sec
Q8BM10
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by SERPINA5. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MYRSCVVRARKRTCVEPWVIGIISFLSLIVLAVCIGLTVHYVRYNHRRTYNYYSTLSFTSDKLYSEFGREASKNFTEMSQRIETMVKHAFHKSPLRGQLVKAHIIKFSKEDDGVLAHMLLIFRIRSTEDPETVHKIIEYVLHEKLKYATGPPNVDPESVKIKKINKTESDNYFNHCCGTRRNKSTVQTSVRIVGGTPVEEEEWPWQSSLRWDGSHRCGATLINNTWLVTAAHCFRTHKDPSRWSATFGATLQPRKLTTGIRRIIVHEKYKYPSHDYDIALAELSKPVPCTNAVHKVCLPDANHEFQPGQRMFVTGFGALKNDGFTQNNLRQVQVDYIDTQTCNQPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVTADVRDIWYLAGVVSWGDECGQPNKPGVYTRVTAFRHWIASNTGI
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. {ECO:0000269|PubMed:15328353}.
uniprot
proteins
mass_dalton
48065
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:15328353}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
15328353
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15328353}; Single-pass type II membrane protein {ECO:0000269|PubMed:15328353}.; SUBCELLULAR LOCATION: [Transmembrane protease serine 11E catalytic chain]: Secreted {ECO:0000269|PubMed:15328353}. Note=Activated by cleavage and secreted. {ECO:0000269|PubMed:15328353}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins