Efemp1
entrez
216616
canonical
uniprot
Q8BPB5
canonical
ensembl
ENSMUSG00000020467
resolver
ensp
ENSMUSP00000020759
resolver
ensp
ENSMUSP00000293078
resolver
enst
ENSMUST00000020759
resolver
genesymbol
Efemp1
resolver
genesymbol_syn
Fbln3
resolver
uniprot
Q6Y3N6
resolver
uniprot_entry
FBLN3_MOUSE
resolver
uniprot_sec
Q6Y3N6
resolver
amino_acid_sequence
MLQTLFLTMLTLALVKSQYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
uniprot
proteins
function
FUNCTION: Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth (By similarity). {ECO:0000250|UniProtKB:Q12805}.
uniprot
proteins
mass_dalton
54953
uniprot
proteins
protein_family
Fibulin family
uniprot
proteins
pubmed
12915309
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17872905
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26162006
uniprot
proteins
sequence_length
493
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:26162006}. Note=Localizes to the lamina propria underneath the olfactory epithelium. {ECO:0000250|UniProtKB:O35568}.
uniprot
proteins