Ppat
entrez
117544
canonical
uniprot
P35433
canonical
ensembl
ENSRNOG00000002128
resolver
ensembl
ENSRNOG00055005127
resolver
ensembl
ENSRNOG00060017990
resolver
ensembl
ENSRNOG00065020270
resolver
ensp
ENSRNOP00000087004
resolver
ensp
ENSRNOP00000106250
resolver
ensp
ENSRNOP00055006190
resolver
ensp
ENSRNOP00060025024
resolver
ensp
ENSRNOP00065027427
resolver
enst
ENSRNOT00000100016
resolver
enst
ENSRNOT00000169394
resolver
enst
ENSRNOT00055008218
resolver
enst
ENSRNOT00060030904
resolver
enst
ENSRNOT00065034250
resolver
genesymbol
Ppat
resolver
uniprot
A0A8I6A2E8
resolver
uniprot_entry
A0A8I6A2E8_RAT
resolver
uniprot_entry
PUR1_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Activated by the substrate 5-phospho-alpha-D-ribosyl-1-pyrophosphate and inhibited by the purine ribonucleotides, the end products of purine biosynthesis.
uniprot
proteins
amino_acid_sequence
MELEESGIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPKFRVHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPAAYSLVIMHRDVIYAVRDPYGNRPLCIGRLMPVSDINDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKPGEIVEISRHGVRTLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAVEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKHPCFMGINIPTKEELIANKPEFEYLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQKVKKRDITIQENGNGLEYFEKTGHCTACLTGQYPVDLEW
uniprot
proteins
ec_number
2.4.2.14
uniprot
proteins
function
FUNCTION: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. {ECO:0000269|PubMed:8463258}.
uniprot
proteins
mass_dalton
57437
uniprot
proteins
pathway_participation
PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. {ECO:0000269|PubMed:8463258}.
uniprot
proteins
protein_family
Purine/pyrimidine phosphoribosyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7742366
uniprot
proteins
pubmed
8463258
uniprot
proteins
sequence_length
517
uniprot
proteins