RDH10
entrez
157506
canonical
uniprot
Q8IZV5
canonical
ensembl
ENSG00000121039
resolver
ensp
ENSP00000240285
resolver
enst
ENST00000240285
resolver
genesymbol
RDH10
resolver
genesymbol_syn
SDR16C4
resolver
hgnc
HGNC:19975
resolver
uniprot_entry
RDH10_HUMAN
resolver
amino_acid_sequence
MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI
uniprot
proteins
ec_number
1.1.1.300
uniprot
proteins
function
FUNCTION: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. {ECO:0000269|PubMed:12407145}.
uniprot
proteins
mass_dalton
38087
uniprot
proteins
pathway_participation
PATHWAY: Cofactor metabolism; retinol metabolism.
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
12407145
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14596915
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Microsome membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 3..23; /note="Helical; Signal-anchor"; /evidence="ECO:0000255
uniprot
proteins