Pts
entrez
29498
canonical
uniprot
P27213
canonical
ensembl
ENSRNOG00000009250
resolver
ensembl
ENSRNOG00055027317
resolver
ensembl
ENSRNOG00060015615
resolver
ensembl
ENSRNOG00065016807
resolver
ensp
ENSRNOP00000012434
resolver
ensp
ENSRNOP00055038882
resolver
ensp
ENSRNOP00060021430
resolver
ensp
ENSRNOP00065022172
resolver
enst
ENSRNOT00000012434
resolver
enst
ENSRNOT00055047302
resolver
enst
ENSRNOT00060026755
resolver
enst
ENSRNOT00065028056
resolver
genesymbol
Pts
resolver
uniprot_entry
PTPS_RAT
resolver
amino_acid_sequence
MNAAVGLRRRARLSRLVSFSASHRLHSPSLSAEENLKVFGKCNNPNGHGHNYKVVVTIHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADVVSTTENVAVYIWENLQRLLPVGALYKVKVYETDNNIVVYKGE
uniprot
proteins
disease_involvement
DISEASE: Note=Deficiency leads to phenylketonuria.
uniprot
proteins
ec_number
4.2.3.12
uniprot
proteins
function
FUNCTION: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
uniprot
proteins
mass_dalton
16241
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Ser-18 is required for maximal enzyme activity. {ECO:0000250}.
uniprot
proteins
protein_family
PTPS family
uniprot
proteins
pubmed
10024455
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1939130
uniprot
proteins
pubmed
8137809
uniprot
proteins
sequence_length
144
uniprot
proteins