Senp7
entrez
288167
canonical
uniprot
D3ZF42
canonical
ensembl
ENSRNOG00000001616
resolver
ensp
ENSRNOP00000043376
resolver
ensp
ENSRNOP00000082802
resolver
ensp
ENSRNOP00000083696
resolver
ensp
ENSRNOP00000084584
resolver
enst
ENSRNOT00000106202
resolver
enst
ENSRNOT00000113252
resolver
enst
ENSRNOT00000117624
resolver
genesymbol
Senp7
resolver
genesymbol_syn
Susp2
resolver
uniprot
A0A8I5ZVM4
resolver
uniprot
A0A8I5ZZN8
resolver
uniprot
A0A8I5ZZQ8
resolver
uniprot_entry
A0A8I5ZVM4_RAT
resolver
uniprot_entry
A0A8I5ZZN8_RAT
resolver
uniprot_entry
A0A8I5ZZQ8_RAT
resolver
uniprot_entry
SENP7_RAT
resolver
amino_acid_sequence
MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLPKLRGSECWWTRSLRNKVICLDHKTTKAAHGCPPKALPKRHLKVMLTNVLWTDLGREFRKTLPRNDAKLCDTSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERIPRVILTDIRQTELGRKYLKIPSVTEASLSDTASPKSEELSSSADGSLESCQNVNHLKSFLSERGSKPSRTGDISAKEAANGRQEQGDDGDIAPEMVTPQSKDFNSGNKGDYHEEGTSNKNTSYSHSETDHTPVSRKRKKRGRSNFHNSHNPKSSVDKSTEYIKEEENESTVSSKLEESNEDSHQDPAPPEGLTPDSLETEATNVCSFVVQEPDVSAASGRACSPNKSSESSVSSEVAENSSAAEKGEASTVKEAPPPGGNSEENQLLMSAEPIVVSSDEEGPVEHKNSVILKLQPSQDYEFMSENQTTSDPQLSELMLGACESVQVSSELCPYNPDMENISCINPNSEMDLKLDFIFTCVYIGKIKGTSKGCITFTKKYIKIPFQVSMNEISLTVDTARLKRFGLWESKDDDHSKRSHAILFLWVSSNYLQDIQTQLENPMLSQQSKANEFIFLELNSPISQREELKLKDIMMEIGATNGELQLSCPLPWVQAFPLFQDLSPQEISFLHYYCASASSFPAVAGADMKKKPVSQPSNADVVKPTYTFLHKQSSGCYSLSITSSPDEEWREVRNTGPVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQEFQDQQSQHDNKTIDNDPHTTSTVFTSAEESQSTETSMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS
uniprot
proteins
ec_number
3.4.22.-
uniprot
proteins
function
FUNCTION: Protease that acts as a positive regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS. Desumoylation of CGAS promotes DNA-binding activity of CGAS, subsequent oligomerization and activation (By similarity). Deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms (By similarity). {ECO:0000250|UniProtKB:Q8BUH8, ECO:0000250|UniProtKB:Q9BQF6}.
uniprot
proteins
mass_dalton
116872
uniprot
proteins
protein_family
Peptidase C48 family
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1037
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8BUH8}.
uniprot
proteins