PADI2
entrez
11240
canonical
uniprot
Q9Y2J8
canonical
ensembl
ENSG00000117115
resolver
ensembl
ENSG00000291387
resolver
ensp
ENSP00000364635
resolver
ensp
ENSP00000645973
resolver
genesymbol
PADI2
resolver
genesymbol_syn
KIAA0994
resolver
genesymbol_syn
PAD2
resolver
genesymbol_syn
PDI2
resolver
hgnc
HGNC:18341
resolver
uniprot
Q96DA7
resolver
uniprot
Q9UPN2
resolver
uniprot_entry
PADI2_HUMAN
resolver
uniprot_sec
Q96DA7
resolver
uniprot_sec
Q9UPN2
resolver
amino_acid_sequence
MLRERTVRLQYGSRVEAVYVLGTYLWTDVYSAAPAGAQTFSLKHSEHVWVEVVRDGEAEEVATNGKQRWLLSPSTTLRVTMSQASTEASSDKVTVNYYDEEGSIPIDQAGLFLTAIEISLDVDADRDGVVEKNNPKKASWTWGPEGQGAILLVNCDRETPWLPKEDCRDEKVYSKEDLKDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRRKLYHVVKYTGGSAELLFFVEGLCFPDEGFSGLVSIHVSLLEYMAQDIPLTPIFTDTVIFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYLNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPVKELLGPDFGYVTREPLFESVTSLDSFGNLEVSPPVTVNGKTYPLGRILIGSSFPLSGGRRMTKVVRDFLKAQQVQAPVELYSDWLTVGHVDEFMSFVPIPGTKKFLLLMASTSACYKLFREKQKDGHGEAIMFKGLGGMSSKRITINKILSNESLVQENLYFQRCLDWNRDILKKELGLTEQDIIDLPALFKMDEDHRARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLEMHVRGLLEPLGLECTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP
uniprot
proteins
ec_number
3.5.3.15
uniprot
proteins
function
FUNCTION: Catalyzes the deimination of arginine residues of proteins. {ECO:0000269|PubMed:12392711, ECO:0000269|PubMed:25621824, ECO:0000269|PubMed:30044909}.
uniprot
proteins
mass_dalton
75564
uniprot
proteins
mutagenesis
MUTAGEN 123; /note="D->N: Mildly reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 125; /note="D->A: Mildly reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 166; /note="D->A: Reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 169; /note="D->A: Mildly reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 177; /note="D->A: Reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 348; /note="W->A: Loss of enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 350; /note="Q->A: Strongly reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 354; /note="E->A: Loss of enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 370; /note="D->A: Reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 373; /note="R->A: Strongly reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 374; /note="D->A: Reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 389; /note="D->A: Reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 412; /note="E->A: Strongly reduced enzyme activity."; /evidence="ECO:0000269|PubMed:25621824"; MUTAGEN 647; /note="C->A: Loss of enzyme activity."; /evidence="ECO:0000269|PubMed:25621824
uniprot
proteins
protein_family
Protein arginine deiminase family
uniprot
proteins
pubmed
10231032
uniprot
proteins
pubmed
12392711
uniprot
proteins
pubmed
15087120
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
25621824
uniprot
proteins
pubmed
30044909
uniprot
proteins
sequence_length
665
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12392711}.
uniprot
proteins