Deup1
entrez
234964
canonical
uniprot
Q7M6Y5
canonical
ensembl
ENSMUSG00000039977
resolver
ensp
ENSMUSP00000039912
resolver
ensp
ENSMUSP00000111256
resolver
ensp
ENSMUSP00000162656
resolver
ensp
ENSMUSP00000162657
resolver
ensp
ENSMUSP00000362201
resolver
ensp
ENSMUSP00000362202
resolver
genesymbol
Deup1
resolver
genesymbol_syn
Ccdc67
resolver
uniprot
E9QL16
resolver
uniprot
Q4VA46
resolver
uniprot
U5KUF9
resolver
uniprot_entry
DEUP1_MOUSE
resolver
uniprot_entry
U5KUF9_MOUSE
resolver
uniprot_sec
E9QL16
resolver
uniprot_sec
Q4VA46
resolver
amino_acid_sequence
MENQAHTTAGASPCEAELQELMEQIDIMVSNKKLDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLVMTQNYEGQLQTLKAQFSKLTSNFEKLRLHQMKQNQIHRKESSSKEELPFELSSLNQKLEEFRAKSREWDKQEVLYQTHLVSLDAQQKLLSEKCSQFQKQAQNYQTQLNGKKQCAEDSSSEIPRLVCESDPGCEATQRDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLHLHRELLRMGEVQTAQDNRKRVESSYSPSPKEAERKRKELFPMVSDQPNHEKELSKMRSQLYQEEGLCSEQERLRSEISELTQELHQKEVTIATVMKKAALLERQLKIELEIKERMLAKQQVSDRRYKAVRTENTHLKGMMGDLDPARYLAVDLSNKKHSQCTSINKLEYENERLRSDLAKLHGNGKAAWPNQSSYGEAGAYVFQSQLKTETSGDRISQDCELNRSPTPLSPLPFQTKEMASPLVGDNEVLALSPPDISFRASLAAQHFLMEEERRAKELEKLLNTHIDELQRHTEFTLNKYTKLKQSRHI
uniprot
proteins
function
FUNCTION: Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis. {ECO:0000269|PubMed:24240477}.
uniprot
proteins
mass_dalton
69678
uniprot
proteins
protein_family
CEP63 family
uniprot
proteins
pubmed
12783626
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
24240477
uniprot
proteins
sequence_length
601
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:24240477}. Note=Localizes to the deuterosome.
uniprot
proteins