FAM64A
entrez
54478
canonical
uniprot
Q9BSJ6
canonical
ensembl
ENSG00000129195
resolver
ensp
ENSP00000250056
resolver
ensp
ENSP00000458534
resolver
ensp
ENSP00000459235
resolver
ensp
ENSP00000459597
resolver
ensp
ENSP00000460894
resolver
enst
ENST00000570337
resolver
enst
ENST00000571373
resolver
genesymbol
FAM64A
resolver
genesymbol
PIMREG
resolver
genesymbol_syn
CATS
resolver
genesymbol_syn
FAM64A
resolver
genesymbol_syn
RCS1
resolver
hgnc
HGNC:25483
resolver
uniprot
A0A0S2Z5C7
resolver
uniprot
A0A0S2Z5F0
resolver
uniprot
I3L419
resolver
uniprot
Q96CT4
resolver
uniprot
Q9NVV1
resolver
uniprot
Q9NWB5
resolver
uniprot_entry
A0A0S2Z5C7_HUMAN
resolver
uniprot_entry
A0A0S2Z5F0_HUMAN
resolver
uniprot_entry
I3L419_HUMAN
resolver
uniprot_entry
PIMRE_HUMAN
resolver
uniprot_sec
Q96CT4
resolver
uniprot_sec
Q9NVV1
resolver
uniprot_sec
Q9NWB5
resolver
amino_acid_sequence
MASRWQNMGTSVRRRSLQHQEQLEDSKELQPVVSHQETSVGALGSLCRQFQRRLPLRAVNLNLRAGPSWKRLETPEPGQQGLQAAARSAKSALGAVSQRIQESCQSGTKWLVETQVKARRRKRGAQKGSGSPTHSLSQKSTRLSGAAPAHSAADPWEKEHHRLSVRMGSHAHPLRRSRREAAFRSPYSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQELDEAIMAEERKQALSDRQGFILKDVYASP
uniprot
proteins
function
FUNCTION: During mitosis, may play a role in the control of metaphase-to-anaphase transition. {ECO:0000269|PubMed:18757745}.
uniprot
proteins
mass_dalton
27480
uniprot
proteins
mutagenesis
MUTAGEN 14..17; /note="RRSL->ARSA: Weak reduction in ubiquitination. Complete loss of ubiquitination; when associated with 53-A--A-56."; /evidence="ECO:0000269|PubMed:18757745"; MUTAGEN 53..56; /note="RLPL->ALPA: Great reduction in ubiquitination. Complete loss of ubiquitination; when associated with 14-A--A-17."; /evidence="ECO:0000269|PubMed:18757745"; MUTAGEN 129; /note="S->A: No effect on phosphorylation."; /evidence="ECO:0000269|PubMed:23419774"; MUTAGEN 131; /note="S->A: Reduced phosphorylation."; /evidence="ECO:0000269|PubMed:23419774
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C) complex in the presence of FZR1, leading to its degradation by the proteasome during mitotic exit. However, degradation is not essential for normal mitotic progression within a single cell cycle. {ECO:0000269|PubMed:18757745}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16491119
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
18757745
uniprot
proteins
pubmed
19383357
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23419774
uniprot
proteins
sequence_length
248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16491119, ECO:0000269|PubMed:19383357}. Nucleus, nucleolus {ECO:0000269|PubMed:19383357}. Note=Partially localizes to the nucleolus. {ECO:0000269|PubMed:19383357}.
uniprot
proteins