Lpar2
entrez
53978
canonical
uniprot
Q9JL06
canonical
ensembl
ENSMUSG00000031861
resolver
ensp
ENSMUSP00000034325
resolver
ensp
ENSMUSP00000128261
resolver
enst
ENSMUST00000034325
resolver
enst
ENSMUST00000164890
resolver
genesymbol
Lpar2
resolver
genesymbol_syn
Edg4
resolver
genesymbol_syn
Lpa2
resolver
uniprot
Q6P290
resolver
uniprot_entry
LPAR2_MOUSE
resolver
uniprot_sec
Q6P290
resolver
amino_acid_sequence
MGQCYYNETIGFFYNNSGKELSLHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGMAYLFLMFHTGPRTARLSIKGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVTLIVGVWAAALGLGLLPAHFWHCLCDLDSCSRMVPLFSRSYLAAWALSSLLVFLLMVAVYTRIFFYVRRRVERMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLDCKSCNVLAVEKYFLLLAEANSLVNAVVYSCRDAEMRRTFRRLLCCMCLRWSSHKSARYSASAQTGASTRIMLPENGRPLMDSTL
uniprot
proteins
function
FUNCTION: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
39003
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10729222
uniprot
proteins
pubmed
11093753
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
348
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell surface {ECO:0000250}. Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA colocalizes with RALA in the endocytic vesicles. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 31..51; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 67..87; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 105..124; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 145..165; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 186..206; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 240..260; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 271..291; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins