NDRG2
entrez
57447
canonical
uniprot
Q9UN36
canonical
ensembl
ENSG00000165795
resolver
ensp
ENSP00000298687
resolver
ensp
ENSP00000344620
resolver
ensp
ENSP00000353649
resolver
ensp
ENSP00000380943
resolver
ensp
ENSP00000380945
resolver
ensp
ENSP00000380949
resolver
ensp
ENSP00000380951
resolver
ensp
ENSP00000380956
resolver
ensp
ENSP00000385889
resolver
ensp
ENSP00000451712
resolver
ensp
ENSP00000452006
resolver
ensp
ENSP00000452038
resolver
ensp
ENSP00000452216
resolver
ensp
ENSP00000452306
resolver
ensp
ENSP00000546764
resolver
ensp
ENSP00000546786
resolver
ensp
ENSP00000546788
resolver
ensp
ENSP00000546790
resolver
ensp
ENSP00000546791
resolver
ensp
ENSP00000546794
resolver
ensp
ENSP00000546800
resolver
ensp
ENSP00000546807
resolver
ensp
ENSP00000546810
resolver
ensp
ENSP00000619316
resolver
ensp
ENSP00000656227
resolver
genesymbol
NDRG2
resolver
genesymbol_syn
KIAA1248
resolver
genesymbol_syn
SYLD
resolver
hgnc
HGNC:14460
resolver
uniprot
B3KUE3
resolver
uniprot
B4DE86
resolver
uniprot
B7WP11
resolver
uniprot
B7WPD5
resolver
uniprot
D3DS07
resolver
uniprot
D3DS10
resolver
uniprot
Q567T1
resolver
uniprot
Q68DW2
resolver
uniprot
Q86U08
resolver
uniprot
Q86U46
resolver
uniprot
Q96FD3
resolver
uniprot
Q96FT0
resolver
uniprot
Q96JU0
resolver
uniprot
Q96PN0
resolver
uniprot
Q9BQH5
resolver
uniprot
Q9ULH2
resolver
uniprot_entry
NDRG2_HUMAN
resolver
uniprot_sec
B3KUE3
resolver
uniprot_sec
B4DE86
resolver
uniprot_sec
B7WP11
resolver
uniprot_sec
B7WPD5
resolver
uniprot_sec
D3DS07
resolver
uniprot_sec
D3DS10
resolver
uniprot_sec
Q567T1
resolver
uniprot_sec
Q68DW2
resolver
uniprot_sec
Q86U08
resolver
uniprot_sec
Q86U46
resolver
uniprot_sec
Q96FD3
resolver
uniprot_sec
Q96FT0
resolver
uniprot_sec
Q96JU0
resolver
uniprot_sec
Q96PN0
resolver
uniprot_sec
Q9BQH5
resolver
uniprot_sec
Q9ULH2
resolver
amino_acid_sequence
MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC
uniprot
proteins
function
FUNCTION: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation. {ECO:0000269|PubMed:12845671, ECO:0000269|PubMed:16103061, ECO:0000269|PubMed:21247902}.
uniprot
proteins
mass_dalton
40798
uniprot
proteins
mutagenesis
MUTAGEN 186; /note="L->D: Decreased interaction with CTNNB1. Abolishes down-regulation of Wnt signaling."; /evidence="ECO:0000269|PubMed:21247902
uniprot
proteins
protein_family
NDRG family
uniprot
proteins
pubmed
10574462
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11352569
uniprot
proteins
pubmed
11936845
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
12845671
uniprot
proteins
pubmed
14572661
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15207261
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15526377
uniprot
proteins
pubmed
16103061
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21247902
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
371
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone {ECO:0000250}. Note=In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons (By similarity). {ECO:0000250}.
uniprot
proteins