Man1a
entrez
17155
canonical
uniprot
P45700
canonical
ensembl
ENSMUSG00000003746
resolver
ensp
ENSMUSP00000003843
resolver
ensp
ENSMUSP00000101110
resolver
ensp
ENSMUSP00000151568
resolver
enst
ENSMUST00000003843
resolver
enst
ENSMUST00000105470
resolver
genesymbol
Man1a
resolver
genesymbol
Man1a1
resolver
genesymbol_syn
Man1a
resolver
uniprot
Q544T7
resolver
uniprot_entry
MA1A1_MOUSE
resolver
uniprot_entry
Q544T7_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by both 1-deoxymannojirimycin and kifunensine. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MPVGGLLPLFSSPGGGGLGSGLGGGLGGGRKGSGPAAFRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSNPALQPPAEHKPGLGARAEDAAEGRVRHREEGAPGDPGAGLEDNLARIRENHERALREAKETLQKLPEEIQRDILLEKEKVAQDQLRDKDLFRGLPKVDFLPPVGVENREPADATIREKRAKIKEMMTHAWNNYKRYAWGLNELKPISKEGHSSSLFGNIKGATIVDALDTLFIMGMKTEFQEAKSWIKKYLDFNVNAEVSVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGDPVFAEKVMKIRTVLNKLDKPEGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSGGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADGAPEARAQHYLELGAEIARTCHESYNRTYVKLGPEAFRFDGGVEAIATRQNEKYYILRPEVIETYMYMWRLTHDPKYRTWAWEAVEALESHCRVNGGYSGLRDVYIARESYDDVQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNTEAHPFPILREQKKEIDGKEK
uniprot
proteins
ec_number
3.2.1.113
uniprot
proteins
function
FUNCTION: Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
uniprot
proteins
mass_dalton
73276
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:P32906}.
uniprot
proteins
post_translational_modification
PTM: N-linked glycan at Asn-515 consists of Man(6)-GlcNAc(2). {ECO:0000269|PubMed:15102839}.
uniprot
proteins
protein_family
Glycosyl hydrolase 47 family
uniprot
proteins
pubmed
15102839
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8144580
uniprot
proteins
sequence_length
655
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type II membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 44..64; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins