Nobox
entrez
18291
canonical
uniprot
Q8VIH1
canonical
ensembl
ENSMUSG00000029736
resolver
ensp
ENSMUSP00000031749
resolver
enst
ENSMUST00000031749
resolver
genesymbol
Nobox
resolver
genesymbol_syn
Og2x
resolver
uniprot
P70367
resolver
uniprot_entry
NOBOX_MOUSE
resolver
uniprot_sec
P70367
resolver
amino_acid_sequence
MEPTEKLCKKMQGQEAGDKPRTAALETEGPLQDSALPIQDDQDKQSSLPRASLGKRPLSKTSEELMDAGTCRVHKAPTAAACGPQSEEEGCSPPERKAESLKPSISAVPGQATAGSLNSHEGDLKKESLEVTCQFRKKTRTLYRSDQLEELERIFQEDHYPDSDKRHEISQMVGVTPQRIMVWFQNRRAKWRKVEKLNEKETKNGPAAPSADSSQHRSAPELLDPMPTDLEPGPVPPENILDVFPEPPMLLTSEQTLTPFQNNEGAERVAVTPPLLSPPPIRRANLPLPLGPVQTPQVLPPMRDVPGSDSIYKDKAYVSWGTSIASPPTYSNLEDLGSQDYQASSQLGSFQLSQAPHLPLFPSLQSQFPYLPPFPYPIPSSMPFLPPEDSLFSFPFGFSGDSSQDYCPGPPPGQILLQPPAENMGTGPWSGHCLPEPPFPRPHYPQALGQPLGAEGYFPNLLPTPYALTMSKQSSLGLNGLLEGTRVETGSSLSKMSDEQTSSSLEQPALEEVRDKNKNSHAAGAKE
uniprot
proteins
function
FUNCTION: Transcription factor which plays an essential role in postnatal follicle development. Binds preferentially to the DNA sequences 5'-TAATTG-3', 5'-TAGTTG-3' and 5'-TAATTA-3'. Directly regulates the transcription of POU5F1 and GDF9 during early folliculogenesis. {ECO:0000269|PubMed:15326356, ECO:0000269|PubMed:16997917}.
uniprot
proteins
mass_dalton
57565
uniprot
proteins
mutagenesis
MUTAGEN 186; /note="N->Q: Abolishes DNA-binding."; /evidence="ECO:0000269|PubMed:16997917"; MUTAGEN 187; /note="R->H: Abolishes DNA-binding."; /evidence="ECO:0000269|PubMed:17701902"; MUTAGEN 192; /note="R->Q: No effect on DNA-binding."; /evidence="ECO:0000269|PubMed:17701902
uniprot
proteins
pubmed
11804785
uniprot
proteins
pubmed
15326356
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16997917
uniprot
proteins
pubmed
17701902
uniprot
proteins
pubmed
8855241
uniprot
proteins
sequence_length
527
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins