Slurp2
entrez
69462
canonical
uniprot
P0DP59
canonical
ensembl
ENSMUSG00000075605
resolver
ensp
ENSMUSP00000051457
resolver
enst
ENSMUST00000057932
resolver
genesymbol
Slurp2
resolver
uniprot
Q08EF7
resolver
uniprot
Q3TRB5
resolver
uniprot
Q9WVC2
resolver
uniprot_entry
SLUR2_MOUSE
resolver
uniprot_sec
Q08EF7
resolver
uniprot_sec
Q3TRB5
resolver
uniprot_sec
Q9WVC2
resolver
amino_acid_sequence
MRLPFWFLLAVVLSMELAVTQGLQCHLCKGFGGCSRPSSCPWSSTHCVIIATRSPISFTDLPLVTKMCYSGCPDVSSLGLGPHVSIACCQSNLCNRD
uniprot
proteins
function
FUNCTION: Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs, strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner. {ECO:0000250|UniProtKB:P0DP57}.
uniprot
proteins
mass_dalton
10452
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17286989
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
97
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P0DP57}.
uniprot
proteins