MLXIP
entrez
22877
canonical
uniprot
Q9HAP2
canonical
ensembl
ENSG00000175727
resolver
ensembl
ENSG00000281178
resolver
ensp
ENSP00000312834
resolver
ensp
ENSP00000560571
resolver
ensp
ENSP00000788573
resolver
genesymbol
MLXIP
resolver
genesymbol_syn
BHLHE36
resolver
genesymbol_syn
KIAA0867
resolver
genesymbol_syn
MIR
resolver
genesymbol_syn
MONDOA
resolver
hgnc
HGNC:17055
resolver
uniprot
A7MBN0
resolver
uniprot
O94945
resolver
uniprot
Q7LC47
resolver
uniprot
Q8IXP1
resolver
uniprot
Q8TAH9
resolver
uniprot
Q8WVQ0
resolver
uniprot
Q8WYA5
resolver
uniprot_entry
MLXIP_HUMAN
resolver
uniprot_sec
A7MBN0
resolver
uniprot_sec
O94945
resolver
uniprot_sec
Q7LC47
resolver
uniprot_sec
Q8IXP1
resolver
uniprot_sec
Q8TAH9
resolver
uniprot_sec
Q8WVQ0
resolver
uniprot_sec
Q8WYA5
resolver
amino_acid_sequence
MAADVFMCSPRRPRSRGRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLVQDDDMLYWHKHGDGWKTPVPMEEDPLLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAITLQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQLSTSTSILTDPAQLPEQASKAVTRIGKRLGES
uniprot
proteins
function
FUNCTION: Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. {ECO:0000250|UniProtKB:Q2VPU4, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}.
uniprot
proteins
mass_dalton
101185
uniprot
proteins
pubmed
10048485
uniprot
proteins
pubmed
11073985
uniprot
proteins
pubmed
12446771
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16782875
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
919
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}. Mitochondrion outer membrane {ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}. Note=Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus. {ECO:0000250|UniProtKB:Q2VPU4, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}.
uniprot
proteins