DNAJC27
entrez
51277
canonical
uniprot
Q9NZQ0
canonical
ensembl
ENSG00000115137
resolver
ensp
ENSP00000264711
resolver
ensp
ENSP00000440086
resolver
ensp
ENSP00000786126
resolver
genesymbol
DNAJC27
resolver
genesymbol_syn
RABJS
resolver
genesymbol_syn
RBJ
resolver
hgnc
HGNC:30290
resolver
uniprot
Q5JV88
resolver
uniprot
Q86Y24
resolver
uniprot_entry
DJC27_HUMAN
resolver
uniprot_sec
Q5JV88
resolver
uniprot_sec
Q86Y24
resolver
amino_acid_sequence
MEANMPKRKEPGRSLRIKVISMGNAEVGKSCIIKRYCEKRFVSKYLATIGIDYGVTKVHVRDREIKVNIFDMAGHPFFYEVRNEFYKDTQGVILVYDVGQKDSFDALDAWLAEMKQELGPHGNMENIIFVVCANKIDCTKHRCVDESEGRLWAESKGFLYFETSAQTGEGINEMFQTFYISIVDLCENGGKRPTTNSSASFTKEQADAIRRIRNSKDSWDMLGVKPGASRDEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK
uniprot
proteins
function
FUNCTION: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. {ECO:0000250|UniProtKB:Q8CFP6}.
uniprot
proteins
mass_dalton
30855
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
14980719
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
24746703
uniprot
proteins
sequence_length
273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8CFP6}.
uniprot
proteins