Lax1
entrez
498232
canonical
uniprot
Q5FVQ5
canonical
ensembl
ENSRNOG00000028250
resolver
ensembl
ENSRNOG00055021778
resolver
ensembl
ENSRNOG00060017402
resolver
ensp
ENSRNOP00000108130
resolver
ensp
ENSRNOP00055030394
resolver
ensp
ENSRNOP00060023957
resolver
enst
ENSRNOT00055037309
resolver
enst
ENSRNOT00060029741
resolver
genesymbol
Lax1
resolver
genesymbol_syn
Lax
resolver
uniprot_entry
LAX1_RAT
resolver
amino_acid_sequence
MYTTPAPPEITRRSSEPSTQQGTLGSLEGEKGHLLFPGFVVLVTIFLVVIVTCILWSRKKQKKRRVPYLQVTPSLALPPPRQRAKNIYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEVPQASGSLQKHRASVHAVEYTVGVYDNGTVAQMCGPLASSAHRVCDGTSRNNSISSKESNDYVNIPTAEDTSETLTCTKSTPESHLGLPSGQRLEFAEGGHAGCGKATDRTGVWAPGLQGSNSLSEGDDSSQSSNDYVNMTGLDLEDIQESRPRVAFQCCRDYENVPPVVANGSQLQTVEEVTSSTTDRGEPAQRTLPSVYHMAFRPSAWSEDGAMIPGEEASNGDSSDYENVLVPELEGKDWKQGPGTWHPSDERTPSDQAGKFCEAVYPAGSLATETSGEEV
uniprot
proteins
function
FUNCTION: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells. {ECO:0000250}.
uniprot
proteins
mass_dalton
43936
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosines upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
406
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 34..54; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins