Cnbp
entrez
64530
canonical
uniprot
P62634
canonical
ensembl
ENSRNOG00000010239
resolver
ensp
ENSRNOP00000013884
resolver
genesymbol
Cnbp
resolver
genesymbol_syn
Znf9
resolver
uniprot
P20694
resolver
uniprot
Q5QJQ8
resolver
uniprot_entry
CNBP_RAT
resolver
uniprot_sec
P20694
resolver
uniprot_sec
Q5QJQ8
resolver
amino_acid_sequence
MSSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGGFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA
uniprot
proteins
function
FUNCTION: Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (By similarity). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (PubMed:7788528). Binds G-rich elements in target mRNA coding sequences (By similarity). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (By similarity). {ECO:0000250|UniProtKB:P53996, ECO:0000250|UniProtKB:P62633, ECO:0000269|PubMed:7788528}.
uniprot
proteins
mass_dalton
19463
uniprot
proteins
post_translational_modification
PTM: Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding. {ECO:0000250|UniProtKB:P62633}.
uniprot
proteins
pubmed
14505273
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15978772
uniprot
proteins
pubmed
7788528
uniprot
proteins
sequence_length
177
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P53996}. Cytoplasm {ECO:0000250|UniProtKB:P62633}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P53996}.
uniprot
proteins