Sema6d
entrez
214968
canonical
uniprot
Q76KF0
canonical
ensembl
ENSMUSG00000027200
resolver
ensp
ENSMUSP00000061123
resolver
ensp
ENSMUSP00000075674
resolver
ensp
ENSMUSP00000077014
resolver
ensp
ENSMUSP00000099528
resolver
ensp
ENSMUSP00000099529
resolver
ensp
ENSMUSP00000099530
resolver
ensp
ENSMUSP00000099531
resolver
ensp
ENSMUSP00000207840
resolver
ensp
ENSMUSP00000207841
resolver
ensp
ENSMUSP00000207842
resolver
ensp
ENSMUSP00000207843
resolver
ensp
ENSMUSP00000207844
resolver
ensp
ENSMUSP00000207845
resolver
ensp
ENSMUSP00000207847
resolver
ensp
ENSMUSP00000207848
resolver
ensp
ENSMUSP00000207849
resolver
ensp
ENSMUSP00000207850
resolver
ensp
ENSMUSP00000207851
resolver
ensp
ENSMUSP00000207853
resolver
ensp
ENSMUSP00000207854
resolver
ensp
ENSMUSP00000207855
resolver
ensp
ENSMUSP00000207856
resolver
ensp
ENSMUSP00000207857
resolver
ensp
ENSMUSP00000207859
resolver
ensp
ENSMUSP00000207860
resolver
ensp
ENSMUSP00000207862
resolver
ensp
ENSMUSP00000207863
resolver
ensp
ENSMUSP00000207864
resolver
ensp
ENSMUSP00000207865
resolver
enst
ENSMUST00000103240
resolver
genesymbol
Sema6d
resolver
genesymbol_syn
Kiaa1479
resolver
uniprot
A2AW72
resolver
uniprot
A2AW73
resolver
uniprot
Q76KF1
resolver
uniprot
Q76KF2
resolver
uniprot
Q76KF3
resolver
uniprot
Q76KF4
resolver
uniprot
Q80TD0
resolver
uniprot_entry
A2AW73_MOUSE
resolver
uniprot_entry
SEM6D_MOUSE
resolver
uniprot_sec
A2AW72
resolver
uniprot_sec
Q76KF1
resolver
uniprot_sec
Q76KF2
resolver
uniprot_sec
Q76KF3
resolver
uniprot_sec
Q76KF4
resolver
uniprot_sec
Q80TD0
resolver
amino_acid_sequence
MGFLLLWFCVLFLLVSRLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPQTEVIPSKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLRTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDDTLAFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIEVDRSAGPYQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNPAKCSAESEEDRKVVSLQLDKDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGWLSQGVCERVTLGMLPGGYEQDTEYGNTAHLGDCHESLPPSTTPDYKIFGGPTSDMEVSSSSVTTVASSPEITSKVIDTWRPKLTSSRKFVVQDDPNTSDFTDTISGIPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNTDTKSMAVDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHSHGASRKEHPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQSMDHPLTKSSSKREHRRSVDSRNTLNDLLKHLNDPNSNPKAILGEIHMAHQTLMLDPVGPMAEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAVPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY
uniprot
proteins
function
FUNCTION: Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections (By similarity). Ligand of TREM2 with PLXNA1 as coreceptor in dendritic cells, plays a role in the generation of immune responses and skeletal homeostasis (PubMed:16715077). {ECO:0000250, ECO:0000269|PubMed:16715077}.
uniprot
proteins
mass_dalton
119815
uniprot
proteins
protein_family
Semaphorin family
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
14715272
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16715077
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1073
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:16715077}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 663..683; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins