Spry1
entrez
24063
canonical
uniprot
Q9QXV9
canonical
ensembl
ENSMUSG00000037211
resolver
ensp
ENSMUSP00000049292
resolver
ensp
ENSMUSP00000103742
resolver
ensp
ENSMUSP00000103744
resolver
ensp
ENSMUSP00000202257
resolver
ensp
ENSMUSP00000202258
resolver
enst
ENSMUST00000038569
resolver
enst
ENSMUST00000108107
resolver
enst
ENSMUST00000108109
resolver
genesymbol
Spry1
resolver
uniprot
Q53ZU1
resolver
uniprot_entry
Q53ZU1_MOUSE
resolver
uniprot_entry
SPY1_MOUSE
resolver
amino_acid_sequence
MDSPSQHGSHTSLVVIQPPAVEGRQRLDYDRDTQPATILSLDQIKAIRGSNEYTEGPSVARRPAPRTAPRPEKQERTHEIIPANVNSSYEHRPASHPGNARGSVLSRSTSTGSAASSGSSSSVSSEQGLLGRSPPTRPIPGHRSDRVIRTQPKQLLVEDLKASLKEDPTQHKFICEQCGKCKCGECTAPRALPSCLACDRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDDGGSYSDNPCSCSQSHCCSRYLCMGALSLCLPCLLCYPPAKGCLKLCRGCYDWTHRPGCRCRNSNTVYCKLESCPSRAQGKLS
uniprot
proteins
function
FUNCTION: Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (PubMed:29501879). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (PubMed:25576668). {ECO:0000269|PubMed:25576668, ECO:0000269|PubMed:29501879}.
uniprot
proteins
mass_dalton
34004
uniprot
proteins
protein_family
Sprouty family
uniprot
proteins
pubmed
10498682
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16877379
uniprot
proteins
pubmed
17974561
uniprot
proteins
pubmed
25576668
uniprot
proteins
pubmed
29501879
uniprot
proteins
sequence_length
313
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
uniprot
proteins