AP3S2
entrez
10239
canonical
uniprot
P59780
canonical
ensembl
ENSG00000157823
resolver
ensp
ENSP00000338777
resolver
genesymbol
AP3S2
resolver
hgnc
HGNC:571
resolver
uniprot
B2R677
resolver
uniprot
B4DGQ3
resolver
uniprot
O09077
resolver
uniprot
O09149
resolver
uniprot
Q53H83
resolver
uniprot
Q99589
resolver
uniprot_entry
AP3S2_HUMAN
resolver
uniprot_sec
B2R677
resolver
uniprot_sec
B4DGQ3
resolver
uniprot_sec
O09077
resolver
uniprot_sec
O09149
resolver
uniprot_sec
Q53H83
resolver
uniprot_sec
Q99589
resolver
amino_acid_sequence
MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYILQEVVMGGMVLETNMNEIVAQIEAQNRLEKSEGGLSAAPARAVSAVKNINLPEIPRNINIGDLNIKVPNLSQFV
uniprot
proteins
function
FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
uniprot
proteins
mass_dalton
22017
uniprot
proteins
protein_family
Adaptor complexes small subunit family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
9118953
uniprot
proteins
sequence_length
193
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250}.
uniprot
proteins