Pno1
entrez
289809
canonical
uniprot
Q6VBQ8
canonical
ensembl
ENSRNOG00000005524
resolver
ensp
ENSRNOP00000088236
resolver
genesymbol
Pno1
resolver
uniprot_entry
PNO1_RAT
resolver
amino_acid_sequence
METQNTGTEDGFTPVTHRGGRRAKKRQAEQSSAAGQDGDAGRMDTEEARPAKRPVFPPLSGDQLLTGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKDTKDVSALTKAADFVKAFVLGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF
uniprot
proteins
function
FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA. {ECO:0000250|UniProtKB:Q9NRX1}.
uniprot
proteins
mass_dalton
27472
uniprot
proteins
protein_family
PNO1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15497447
uniprot
proteins
sequence_length
248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9NRX1}.
uniprot
proteins