RHCE
entrez
6006
canonical
uniprot
P18577
canonical
ensembl
ENSG00000188672
resolver
ensp
ENSP00000294413
resolver
ensp
ENSP00000311185
resolver
ensp
ENSP00000334570
resolver
ensp
ENSP00000344485
resolver
ensp
ENSP00000345084
resolver
ensp
ENSP00000415417
resolver
genesymbol
RHCE
resolver
genesymbol_syn
RHC
resolver
genesymbol_syn
RHE
resolver
hgnc
HGNC:10008
resolver
uniprot
A0A1L3H056
resolver
uniprot
A0A220QMN8
resolver
uniprot
A7DW68
resolver
uniprot
B7UDF3
resolver
uniprot
B7UDF4
resolver
uniprot
B7UDF5
resolver
uniprot
B7UDF6
resolver
uniprot
B7UDF7
resolver
uniprot
B7UDF8
resolver
uniprot
B7UDF9
resolver
uniprot
B7UDG0
resolver
uniprot
B7UDG1
resolver
uniprot
B7UDG2
resolver
uniprot
B7UDG3
resolver
uniprot
Q02163
resolver
uniprot
Q02164
resolver
uniprot
Q02165
resolver
uniprot
Q16160
resolver
uniprot
Q2MJW0
resolver
uniprot
Q2VC86
resolver
uniprot
Q3LTM6
resolver
uniprot
Q6AZX5
resolver
uniprot
Q6J2U3
resolver
uniprot
Q7RU06
resolver
uniprot
Q8IZT2
resolver
uniprot
Q8IZT3
resolver
uniprot
Q8IZT4
resolver
uniprot
Q8IZT5
resolver
uniprot
Q9UD13
resolver
uniprot
Q9UD14
resolver
uniprot
Q9UD15
resolver
uniprot
Q9UD16
resolver
uniprot
Q9UD73
resolver
uniprot
Q9UD74
resolver
uniprot
Q9UEC2
resolver
uniprot
Q9UEC3
resolver
uniprot
Q9UPN0
resolver
uniprot_entry
A0A220QMN8_HUMAN
resolver
uniprot_entry
RHCE_HUMAN
resolver
uniprot_sec
A0A1L3H056
resolver
uniprot_sec
A7DW68
resolver
uniprot_sec
B7UDF3
resolver
uniprot_sec
B7UDF4
resolver
uniprot_sec
B7UDF5
resolver
uniprot_sec
B7UDF6
resolver
uniprot_sec
B7UDF7
resolver
uniprot_sec
B7UDF8
resolver
uniprot_sec
B7UDF9
resolver
uniprot_sec
B7UDG0
resolver
uniprot_sec
B7UDG1
resolver
uniprot_sec
B7UDG2
resolver
uniprot_sec
B7UDG3
resolver
uniprot_sec
Q02163
resolver
uniprot_sec
Q02164
resolver
uniprot_sec
Q02165
resolver
uniprot_sec
Q16160
resolver
uniprot_sec
Q2MJW0
resolver
uniprot_sec
Q2VC86
resolver
uniprot_sec
Q3LTM6
resolver
uniprot_sec
Q6AZX5
resolver
uniprot_sec
Q6J2U3
resolver
uniprot_sec
Q7RU06
resolver
uniprot_sec
Q8IZT2
resolver
uniprot_sec
Q8IZT3
resolver
uniprot_sec
Q8IZT4
resolver
uniprot_sec
Q8IZT5
resolver
uniprot_sec
Q9UD13
resolver
uniprot_sec
Q9UD14
resolver
uniprot_sec
Q9UD15
resolver
uniprot_sec
Q9UD16
resolver
uniprot_sec
Q9UD73
resolver
uniprot_sec
Q9UD74
resolver
uniprot_sec
Q9UEC2
resolver
uniprot_sec
Q9UEC3
resolver
uniprot_sec
Q9UPN0
resolver
amino_acid_sequence
MSSKYPRSVRRCLPLCALTLEAALILLFYFFTHYDASLEDQKGLVASYQVGQDLTVMAALGLGFLTSNFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFPPGKVVITLFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMNLRHFYVFAAYFGLTVAWCLPKPLPKGTEDNDQRATIPSLSAMLGALFLWMFWPSVNSALLRSPIQRKNAMFNTYYALAVSVVTAISGSSLAHPQRKISMTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISIGGAKCLPVCCNRVLGIHHISVMHSIFSLLGLLGEITYIVLLVLHTVWNGNGMIGFQVLLSIGELSLAIVIALTSGLLTGLLLNLKIWKAPHVAKYFDDQVFWKFPHLAVGF
uniprot
proteins
disease_involvement
DISEASE: Rh-null, amorph type (RHNA) [MIM:617970]: An autosomal recessive condition characterized by red blood cells that lack all Rh antigens, have increased osmotic fragility, diminished lifespan, and show changes in morphology resulting in stomatocytosis. Rh-null individuals have mild to moderate hemolytic anemia. They are at risk of having adverse reactions in response to transfusion or pregnancy, because they may produce antibodies against several of the Rh antigens. {ECO:0000269|PubMed:25413218, ECO:0000269|PubMed:9657769}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane (PubMed:35835865). Mediates the primary membrane attachment site for ANK1 when associated with RHAG (PubMed:35835865). May participate in the ammonium and carbon dioxide transport through the heterotrimer form (Probable). {ECO:0000269|PubMed:35835865, ECO:0000305}.
uniprot
proteins
mass_dalton
45451
uniprot
proteins
protein_family
Ammonium transporter (TC 2.A.49) family
uniprot
proteins
protein_family
Rh subfamily
uniprot
proteins
pubmed
11380456
uniprot
proteins
pubmed
11724987
uniprot
proteins
pubmed
11902138
uniprot
proteins
pubmed
12393640
uniprot
proteins
pubmed
1379850
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
1696722
uniprot
proteins
pubmed
1898705
uniprot
proteins
pubmed
2123099
uniprot
proteins
pubmed
25413218
uniprot
proteins
pubmed
3135863
uniprot
proteins
pubmed
3146980
uniprot
proteins
pubmed
35835865
uniprot
proteins
pubmed
7789951
uniprot
proteins
pubmed
7916743
uniprot
proteins
pubmed
8117271
uniprot
proteins
pubmed
8188244
uniprot
proteins
pubmed
8220426
uniprot
proteins
pubmed
9657769
uniprot
proteins
sequence_length
417
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 12..32; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 44..64; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 125..145; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 172..192; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 203..223; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 238..258; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 265..285; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 287..307; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 331..351; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 358..378; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins