TAAR9
entrez
134860
canonical
uniprot
Q96RI9
canonical
ensembl
ENSG00000237110
resolver
ensp
ENSP00000424607
resolver
enst
ENST00000434551
resolver
genesymbol
TAAR9
resolver
genesymbol_syn
TA3
resolver
genesymbol_syn
TAR3
resolver
genesymbol_syn
TRAR3
resolver
hgnc
HGNC:20977
resolver
uniprot_entry
TAAR9_HUMAN
resolver
amino_acid_sequence
MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
uniprot
proteins
function
FUNCTION: Olfactory receptor specific for trace amines, such as N,N-dimethylcyclohexylamine (DMCHA) and beta-phenylethylamine (beta-PEA) (By similarity). In contrast to mouse and rat orthologs, not activated by triethylamine, cadaverine (CAD) or spermidine (PubMed:34600890). Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors (By similarity). Trace amine-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS) (By similarity). In mature olfactory sensory neurons, TAAR9 is coupled with GNAL/G(olf)G alpha protein and mediates activation of adenylate cyclase activity to activate cAMP signaling and eventually transmit odorant signals to achieve membrane depolarization (By similarity). In immature olfactory sensory neurons, TAAR9 is coupled with GNAS/G(s) G alpha proteins (By similarity). {ECO:0000250|UniProtKB:Q5QD04, ECO:0000269|PubMed:34600890}.
uniprot
proteins
mass_dalton
39016
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11459929
uniprot
proteins
pubmed
34600890
uniprot
proteins
sequence_length
348
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5QD04}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5QD04}.
uniprot
proteins
transmembrane_region
TRANSMEM 34..58; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 69..90; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 106..128; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 149..170; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 197..218; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 257..280; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q5QD04"; TRANSMEM 294..314; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q5QD04
uniprot
proteins