Ripor1
entrez
291974
canonical
uniprot
Q4FZU8
canonical
ensembl
ENSRNOG00000017604
resolver
ensembl
ENSRNOG00055019210
resolver
ensembl
ENSRNOG00060011194
resolver
ensp
ENSRNOP00000023710
resolver
ensp
ENSRNOP00000069592
resolver
ensp
ENSRNOP00000096363
resolver
ensp
ENSRNOP00055026630
resolver
ensp
ENSRNOP00060014785
resolver
enst
ENSRNOT00000089022
resolver
enst
ENSRNOT00055032880
resolver
enst
ENSRNOT00060018958
resolver
genesymbol
Ripor1
resolver
genesymbol_syn
Fam65a
resolver
uniprot
A0A0G2JVR9
resolver
uniprot_entry
A0A0G2JVR9_RAT
resolver
uniprot_entry
RIPR1_RAT
resolver
amino_acid_sequence
MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRNFTVFSPPGPQRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYAALKRGLTAYLEVHQQEQEKLQRQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARYSSTPKPLVQQPEPLPVQVTFRRPESLSSGSMDEEPPLTPALVNGHAPYSRTLSHISEASVDAALTEAMEAVDLKCPAPGPSPLVYPESTHVEHVSSVPPVADNGRSATSPALSTAGPAPTFIDPASSTQLDLVHKATDSGSSELPSITHTMASSTYSAVSPINSVPGLTSTTVGSTHKPMPSPLTSTGSIPSVTDSIQTTTSPTHTTPSPTHTTVSPTHSTPSPTHTTVSPSNAALSPSNATPSLSHSTTSPTQKATMSTHTTSAVGPVQTTTSPISTTVSPSPSVDTAIISSSSAVPSVPGPEARPCSHPTSTPYTKADPTAACTSSPSLASSGPKPLTSPAPDSLEQILKSPSSSPSSIVPEPQRSELSLALVAQAPVPEATGGAGDRRLEEALRTLMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDNDSPGDRPTSSPEVVAEERLDSSNAQCLSTGCSALDATLVQHLYHCSCLLLKLGTFGPLRCQEAWALERLLREARVLQEVCEHSKLWGNAVTSAQEVVQFSASRPGFLTFWDQCTEGLNPFLCPVEQVLLTFCSQYGARLSLRQPGLAEAVCVKFLEDALGQKLPRRPHSGPGEQLTIFQFWSYVEVLDSPSMEAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRLRKDGLRALSSLLVHGNSKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRQLEESLDALPCLFGPSSMASTAF
uniprot
proteins
function
FUNCTION: Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation. {ECO:0000250|UniProtKB:Q6ZS17}.
uniprot
proteins
mass_dalton
131731
uniprot
proteins
protein_family
RIPOR family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1217
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6ZS17}. Golgi apparatus {ECO:0000250|UniProtKB:Q6ZS17}. Note=Localizes to the podocyte major processes and cell body. Colocalized with STK26 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with STK26 upon serum stimulation in a Rho- and PDCD10-dependent manner. {ECO:0000250|UniProtKB:Q68FE6, ECO:0000250|UniProtKB:Q6ZS17}.
uniprot
proteins