Cnot9
entrez
301513
canonical
uniprot
Q5PQL2
canonical
ensembl
ENSRNOG00000016034
resolver
ensembl
ENSRNOG00055010144
resolver
ensembl
ENSRNOG00060006504
resolver
ensembl
ENSRNOG00065008795
resolver
ensp
ENSRNOP00000021548
resolver
ensp
ENSRNOP00055013771
resolver
ensp
ENSRNOP00060007906
resolver
ensp
ENSRNOP00065010474
resolver
enst
ENSRNOT00000021548
resolver
enst
ENSRNOT00055017119
resolver
enst
ENSRNOT00060010666
resolver
enst
ENSRNOT00065014034
resolver
genesymbol
Cnot9
resolver
genesymbol_syn
Rcd1
resolver
genesymbol_syn
Rqcd1
resolver
uniprot_entry
CNOT9_RAT
resolver
amino_acid_sequence
MHSLATAAPVPTALAQVDREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ
uniprot
proteins
function
FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors. May play a role in cell differentiation (By similarity). {ECO:0000250, ECO:0000269|PubMed:18180299}.
uniprot
proteins
mass_dalton
33601
uniprot
proteins
protein_family
CNOT9 family
uniprot
proteins
pubmed
12356739
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18180299
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9JKY0}. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q9JKY0}. Note=NANOS2 promotes its localization to P-body. {ECO:0000250|UniProtKB:Q9JKY0}.
uniprot
proteins