Rabep1
entrez
54189
canonical
uniprot
O35551
canonical
ensembl
ENSMUSG00000020817
resolver
ensp
ENSMUSP00000075619
resolver
ensp
ENSMUSP00000080102
resolver
ensp
ENSMUSP00000136069
resolver
ensp
ENSMUSP00000137267
resolver
ensp
ENSMUSP00000164801
resolver
enst
ENSMUST00000177731
resolver
genesymbol
Rabep1
resolver
genesymbol_syn
Rab5ep
resolver
genesymbol_syn
Rabpt5
resolver
genesymbol_syn
Rabpt5a
resolver
uniprot
A1L322
resolver
uniprot
J3QJV7
resolver
uniprot
Q5QNU3
resolver
uniprot
Q99L08
resolver
uniprot
Q9CRP3
resolver
uniprot
Q9EQF9
resolver
uniprot
Q9JI94
resolver
uniprot_entry
J3QJV7_MOUSE
resolver
uniprot_entry
RABE1_MOUSE
resolver
uniprot_sec
A1L322
resolver
uniprot_sec
Q5QNU3
resolver
uniprot_sec
Q99L08
resolver
uniprot_sec
Q9CRP3
resolver
uniprot_sec
Q9EQF9
resolver
uniprot_sec
Q9JI94
resolver
amino_acid_sequence
MAQPGPAPQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRAKFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEAIDEVKRQWREEVASLQAIMKETVRDYEHQFHLRLEQERAQWAQYRESAEREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRVNKRKDNKKTDTEEEVKIPVVCALTQEESSTPLSNEEEHLDSTHGSVHSLDADLMLPSGDPFSKSDNDMFKDGLRRAQSTDSLGTSSSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFDTVSLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKEKQELEDFLKQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVEVLRELVLKYRENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEMKVNLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLPET
uniprot
proteins
function
FUNCTION: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Forms a complex with RABGEF1 that stimulates RABGEF1-mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (PubMed:25405894). {ECO:0000250|UniProtKB:Q15276, ECO:0000269|PubMed:25405894}.
uniprot
proteins
mass_dalton
99524
uniprot
proteins
post_translational_modification
PTM: Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity. {ECO:0000250}.
uniprot
proteins
protein_family
Rabaptin family
uniprot
proteins
pubmed
11977240
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22841712
uniprot
proteins
pubmed
25405894
uniprot
proteins
pubmed
9427343
uniprot
proteins
sequence_length
862
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Early endosome {ECO:0000250}. Recycling endosome {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}.
uniprot
proteins