Pilrb
entrez
170741
canonical
uniprot
Q2YFS2
canonical
ensembl
ENSMUSG00000066684
resolver
ensp
ENSMUSP00000106606
resolver
enst
ENSMUST00000110978
resolver
genesymbol
Pilrb
resolver
genesymbol_syn
Fdfact
resolver
genesymbol_syn
Pilrb1
resolver
uniprot_entry
PILRB_MOUSE
resolver
amino_acid_sequence
MALLISLPGGTPAMAQVLLLLSSGCLHAGNSERYNRKNGFGVNQPERCSGVQGGSIDIPFSFYFPWKLAKDPQMSIAWKWKDFHGEVIYNSSLPFIHEHFKGRLILNWTQGQTSGVLRILNLKESDQAQYFSRVNLQSTEGMKLWQSIPGTQLNVTQALNTTMRSPFIVTSEFTTAGLEHTSDQRNPSLMNLGAMVTMLLAKVLVIVLVYGWMIFLRWKQRPAH
uniprot
proteins
function
FUNCTION: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. Seems to associate with DAP12 and is a receptor for CD99. May be involved in target cell recognition by natural killer cells and in activation of dendritic cells. {ECO:0000269|PubMed:14970179}.
uniprot
proteins
mass_dalton
25200
uniprot
proteins
pubmed
14970179
uniprot
proteins
sequence_length
224
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 196..216; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins