Myod1
entrez
337868
canonical
uniprot
Q02346
canonical
ensembl
ENSRNOG00000011306
resolver
ensp
ENSRNOP00000015109
resolver
enst
ENSRNOT00000015109
resolver
genesymbol
Myod1
resolver
genesymbol_syn
Myod
resolver
uniprot
A0JPK9
resolver
uniprot
F7F8D2
resolver
uniprot_entry
A0JPK9_RAT
resolver
uniprot_entry
F7F8D2_RAT
resolver
uniprot_entry
MYOD1_RAT
resolver
amino_acid_sequence
MELLSPPLRDTDLLGPDGSLCSFATRDDFYDDPCFDSPDLRFFEDLDPRLVHVGALLKPEEHAHFPTTVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDAAYYSEASSEPRPGKSAAVSSLDCLSSIVERISTDSPAAPSLLLPDAPPESPPGPPEETSSSDAEQGTQTPSPDSTPQCPAGSKPNPIYQVL
uniprot
proteins
function
FUNCTION: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
34359
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation (By similarity). {ECO:0000250}.; PTM: Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function (By similarity). {ECO:0000250}.; PTM: Ubiquitinated on the N-terminus; which is required for proteasomal degradation. {ECO:0000250}.; PTM: Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity. {ECO:0000250}.
uniprot
proteins
pubmed
1321778
uniprot
proteins
pubmed
9234731
uniprot
proteins
sequence_length
318
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins