Esrrg
entrez
26381
canonical
uniprot
P62509
canonical
ensembl
ENSMUSG00000026610
resolver
ensp
ENSMUSP00000027906
resolver
ensp
ENSMUSP00000106563
resolver
ensp
ENSMUSP00000106564
resolver
genesymbol
Esrrg
resolver
genesymbol_syn
Err3
resolver
genesymbol_syn
Kiaa0832
resolver
genesymbol_syn
Nr3b3
resolver
uniprot
O75454
resolver
uniprot
O96021
resolver
uniprot
Q8CHC9
resolver
uniprot
Q9R1F3
resolver
uniprot_entry
ERR3_MOUSE
resolver
uniprot_sec
O75454
resolver
uniprot_sec
O96021
resolver
uniprot_sec
Q8CHC9
resolver
uniprot_sec
Q9R1F3
resolver
amino_acid_sequence
MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
uniprot
proteins
function
FUNCTION: Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle. {ECO:0000269|PubMed:10428842}.
uniprot
proteins
mass_dalton
51306
uniprot
proteins
mutagenesis
MUTAGEN 449; /note="L->A: Loss of transcriptional activation; when associated with A-450."; /evidence="ECO:0000269|PubMed:10428842"; MUTAGEN 450; /note="F->A: Loss of transcriptional activation; when associated with A-449."; /evidence="ECO:0000269|PubMed:10428842"; MUTAGEN 453; /note="M->A: Loss of transcriptional activation; when associated with A-454."; /evidence="ECO:0000269|PubMed:10428842"; MUTAGEN 454; /note="L->A: Loss of transcriptional activation; when associated with A-453."; /evidence="ECO:0000269|PubMed:10428842
uniprot
proteins
post_translational_modification
PTM: Acetylated by PCAF/KAT2 (in vitro). {ECO:0000250}.; PTM: Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. {ECO:0000250}.; PTM: Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. {ECO:0000250}.
uniprot
proteins
protein_family
NR3 subfamily
uniprot
proteins
protein_family
Nuclear hormone receptor family
uniprot
proteins
pubmed
10428842
uniprot
proteins
pubmed
12465718
uniprot
proteins
pubmed
15161930
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28572090
uniprot
proteins
sequence_length
458
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins