Suds3
entrez
71954
canonical
uniprot
Q8BR65
canonical
ensembl
ENSMUSG00000066900
resolver
ensp
ENSMUSP00000083662
resolver
ensp
ENSMUSP00000130535
resolver
enst
ENSMUST00000086471
resolver
enst
ENSMUST00000166397
resolver
genesymbol
Suds3
resolver
genesymbol_syn
Sds3
resolver
uniprot
A0A0R4J243
resolver
uniprot
Q3UC92
resolver
uniprot
Q6P6K1
resolver
uniprot
Q7TNT0
resolver
uniprot
Q8BRR7
resolver
uniprot
Q8K5B4
resolver
uniprot_entry
A0A0R4J243_MOUSE
resolver
uniprot_entry
SDS3_MOUSE
resolver
uniprot_sec
Q3UC92
resolver
uniprot_sec
Q6P6K1
resolver
uniprot_sec
Q7TNT0
resolver
uniprot_sec
Q8BRR7
resolver
uniprot_sec
Q8K5B4
resolver
amino_acid_sequence
MSAAGLLAPAPAPAAAPAAPEYYPEDEEELESAEDDERSCRGRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYRERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYVGQLQRGLFVIRRRSAA
uniprot
proteins
function
FUNCTION: Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways through regulation of apoptosis. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity). {ECO:0000250|UniProtKB:Q9H7L9, ECO:0000269|PubMed:11909966}.
uniprot
proteins
mass_dalton
38107
uniprot
proteins
post_translational_modification
PTM: Polyubiquitinated. 'Lys-63'-polyubiquitinated SUDS3 positively regulates histone deacetylation. Regulated through deubiquitination by USP17L2/USP17 that cleaves 'Lys-63'-linked ubiquitin chains (By similarity). {ECO:0000250|UniProtKB:Q9H7L9}.
uniprot
proteins
protein_family
SDS3 family
uniprot
proteins
pubmed
11909966
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
328
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9H7L9}.
uniprot
proteins