Asb6
entrez
72323
canonical
uniprot
Q91ZU1
canonical
ensembl
ENSMUSG00000039483
resolver
ensp
ENSMUSP00000043462
resolver
enst
ENSMUST00000041726
resolver
genesymbol
Asb6
resolver
uniprot
Q8VEC6
resolver
uniprot_entry
ASB6_MOUSE
resolver
uniprot_sec
Q8VEC6
resolver
amino_acid_sequence
MPFLHGFRRIIFEYQPLVDAILGALGIQDLERQEPLDDSASSEESRILVLTELLEQKAHSPFYQEGVSNALLKMAELGLTRAAAVLLQSGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKNGKTALLHALASSDGVQIHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVCGDKEEAPMINRFCFQVTQLLLAHGADPSECPAHESLTHICLKSFKLHFPLLCFLLESGAAYNCSLHGASCWSGFNLVFERLCSHPGCAEDDSHIELLHKAETVLDLMVTSSQRLQLPENLNIHPVGSLAGKIQALHASLRQLESYPPPLKHLCRVSIRLCLRPWPVDTKVKALPLPDRLKWYLLSAHSDTQDTC
uniprot
proteins
function
FUNCTION: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the regulation of cell proliferation and autophagy by promoting the ubiquitination and degradation of SQSTM1. {ECO:0000250|UniProtKB:Q9NWX5, ECO:0000269|PubMed:15231829}.
uniprot
proteins
mass_dalton
46276
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
protein_family
Ankyrin SOCS box (ASB) family
uniprot
proteins
pubmed
11509662
uniprot
proteins
pubmed
15231829
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
418
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15231829}.
uniprot
proteins