Arrdc3
entrez
309945
canonical
uniprot
Q6TXF1
canonical
ensembl
ENSRNOG00000045649
resolver
ensembl
ENSRNOG00055023151
resolver
ensembl
ENSRNOG00060002727
resolver
ensembl
ENSRNOG00065005415
resolver
ensp
ENSRNOP00000078331
resolver
ensp
ENSRNOP00055032302
resolver
ensp
ENSRNOP00060003067
resolver
ensp
ENSRNOP00065005619
resolver
enst
ENSRNOT00000106948
resolver
enst
ENSRNOT00055039788
resolver
enst
ENSRNOT00060004361
resolver
enst
ENSRNOT00065008034
resolver
genesymbol
Arrdc3
resolver
uniprot_entry
ARRD3_RAT
resolver
amino_acid_sequence
MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNCEEGFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEVKQLVANLRGESLSSGKTETWDGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMDLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLGLSLPERPEAPPSYAEVVTEEQRRNNLAPVSACDDFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSSEDRPSCPSR
uniprot
proteins
function
FUNCTION: Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes. {ECO:0000250|UniProtKB:Q96B67}.
uniprot
proteins
mass_dalton
46301
uniprot
proteins
protein_family
Arrestin family
uniprot
proteins
sequence_length
414
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96B67}. Cell membrane {ECO:0000250|UniProtKB:Q96B67}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96B67}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96B67}. Lysosome {ECO:0000250|UniProtKB:Q96B67}. Endosome {ECO:0000250|UniProtKB:Q96B67}. Early endosome {ECO:0000250|UniProtKB:Q96B67}. Note=Associated with plasma membrane, as well as with endosomes and lysosomes during endocytosis. {ECO:0000250|UniProtKB:Q96B67}.
uniprot
proteins