Slc10a2
entrez
29500
canonical
uniprot
Q62633
canonical
ensembl
ENSRNOG00000037753
resolver
ensembl
ENSRNOG00055013915
resolver
ensembl
ENSRNOG00060004193
resolver
ensembl
ENSRNOG00065002519
resolver
ensp
ENSRNOP00000088268
resolver
ensp
ENSRNOP00000095418
resolver
ensp
ENSRNOP00055019519
resolver
ensp
ENSRNOP00060005281
resolver
ensp
ENSRNOP00065002256
resolver
enst
ENSRNOT00000100219
resolver
enst
ENSRNOT00000113335
resolver
enst
ENSRNOT00055023925
resolver
enst
ENSRNOT00060006994
resolver
enst
ENSRNOT00065003307
resolver
genesymbol
Slc10a2
resolver
genesymbol_syn
Ntcp2
resolver
uniprot_entry
NTCP2_RAT
resolver
amino_acid_sequence
MDNSSVCSPNATFCEGDSCLVTESNFNAILSTVMSTVLTILLAMVMFSMGCNVEINKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFIYTKMWVDSGTIVIPYDSIGISLVALVIPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAIILGMYVTYKKCHGKNDAEFLEKTDNDMDPMPSFQETNKGFQPDEK
uniprot
proteins
function
FUNCTION: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine (PubMed:7860756). Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids. Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation (By similarity). {ECO:0000250|UniProtKB:Q12908, ECO:0000269|PubMed:7860756}.
uniprot
proteins
mass_dalton
38024
uniprot
proteins
protein_family
Bile acid:sodium symporter (BASS) (TC 2.A.28) family
uniprot
proteins
pubmed
7860756
uniprot
proteins
sequence_length
348
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 29..49; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 127..147; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 158..178; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 196..216; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 285..305; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins