Sycn
entrez
245917
canonical
uniprot
O35775
canonical
ensembl
ENSRNOG00055009190
resolver
ensembl
ENSRNOG00055033234
resolver
ensp
ENSRNOP00055012462
resolver
ensp
ENSRNOP00055047350
resolver
enst
ENSRNOT00055015547
resolver
enst
ENSRNOT00055057436
resolver
genesymbol
Sycn
resolver
genesymbol_syn
Sip9
resolver
uniprot_entry
SYCN_RAT
resolver
amino_acid_sequence
MSPLCLLLLALALVAVPGARGACPVPADLKKSDGTRTCARLYENSDPYYDNCCQGPELSVDPGTDLPYLPSDWSNSASSLVVAQRCELTVWSLPGKRGKTRKFSTGSYPRLEEYRKGIFGTWAKSISGLYCKCY
uniprot
proteins
function
FUNCTION: Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues. {ECO:0000269|PubMed:12235484, ECO:0000269|PubMed:15766266, ECO:0000269|PubMed:15817827}.
uniprot
proteins
mass_dalton
14635
uniprot
proteins
post_translational_modification
PTM: Contains intrachain disulfide bonds.
uniprot
proteins
pubmed
10666056
uniprot
proteins
pubmed
10753942
uniprot
proteins
pubmed
11389693
uniprot
proteins
pubmed
11853552
uniprot
proteins
pubmed
12235484
uniprot
proteins
pubmed
15766266
uniprot
proteins
pubmed
15817827
uniprot
proteins
pubmed
16517980
uniprot
proteins
pubmed
9244306
uniprot
proteins
sequence_length
134
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Zymogen granule membrane {ECO:0000269|PubMed:10753942, ECO:0000269|PubMed:11389693, ECO:0000269|PubMed:11853552}; Peripheral membrane protein {ECO:0000269|PubMed:10753942, ECO:0000269|PubMed:11389693, ECO:0000269|PubMed:11853552}; Lumenal side {ECO:0000269|PubMed:10753942, ECO:0000269|PubMed:11389693, ECO:0000269|PubMed:11853552}. Zymogen granule lumen {ECO:0000269|PubMed:11389693}. Note=Associated in a cholesterol-dependent manner with lipid rafts of zymogen granule membranes. {ECO:0000269|PubMed:11389693}.
uniprot
proteins