Ap4m1
entrez
304344
canonical
uniprot
Q2PWT8
canonical
ensembl
ENSRNOG00000001353
resolver
ensembl
ENSRNOG00055011456
resolver
ensembl
ENSRNOG00060020753
resolver
ensembl
ENSRNOG00065000061
resolver
ensp
ENSRNOP00000001827
resolver
ensp
ENSRNOP00055015685
resolver
ensp
ENSRNOP00060029584
resolver
ensp
ENSRNOP00065000100
resolver
enst
ENSRNOT00055019452
resolver
enst
ENSRNOT00060035953
resolver
enst
ENSRNOT00065000101
resolver
genesymbol
Ap4m1
resolver
uniprot_entry
AP4M1_RAT
resolver
amino_acid_sequence
MISQFFILSSKGDPLIYKDFRGDSGGRDVAELFYRKLTGLPGGESPVVMYHDDRHFIHIRHSGLYLVATTSENVSPFSLLELLSRLATLLGDYCGSLNEGTISRNVALVYELLDEVLDYGYVQTTSTDMLRNFIQTEAAVSKPFSLFDLSSVGLFGAETQQNRVAPSSAASRPVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSSSEICIGLTEEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILHLQPPQGELTVMRYQLSDDLPSPLPFRLFPSVQWDQGSGRLQVYLKLRCDLPPKSQALNIHLHLPLPRGVVSLSQELSSPDQKAELGEGALHWDLPRVQGGSQLSGLFQMDVPGLQGPPSRGPSPSAPPLGLGPASLSFELPRHTCSGLQVRFLRLSFSACGNANPHKWVRHLSHSNAYVIRI
uniprot
proteins
function
FUNCTION: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos (By similarity). The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal (PubMed:14572453). {ECO:0000250|UniProtKB:O00189, ECO:0000269|PubMed:14572453}.
uniprot
proteins
mass_dalton
49853
uniprot
proteins
protein_family
Adaptor complexes medium subunit family
uniprot
proteins
pubmed
14572453
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane {ECO:0000305|PubMed:14572453}; Peripheral membrane protein {ECO:0000305|PubMed:14572453}. Early endosome {ECO:0000250|UniProtKB:O00189}. Note=Found in soma and dendritic shafts of neuronal cells. {ECO:0000269|PubMed:14572453}.
uniprot
proteins