PWP1
entrez
11137
canonical
uniprot
Q13610
canonical
ensembl
ENSG00000136045
resolver
ensp
ENSP00000387365
resolver
ensp
ENSP00000445249
resolver
enst
ENST00000541166
resolver
genesymbol
PWP1
resolver
hgnc
HGNC:17015
resolver
uniprot
A8K3R6
resolver
uniprot
B4DJV5
resolver
uniprot
F6SKR6
resolver
uniprot
Q7Z3X9
resolver
uniprot_entry
B4DJV5_HUMAN
resolver
uniprot_entry
F6SKR6_HUMAN
resolver
uniprot_entry
PWP1_HUMAN
resolver
uniprot_sec
A8K3R6
resolver
uniprot_sec
Q7Z3X9
resolver
amino_acid_sequence
MNRSRQVTCVAWVRCGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGGSDEEETGSPSEDGMQSARTQARPREPLEDGDPEDDRTLDDDELAEYDLDKYDEEGDPDAETLGESLLGLTVYGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHVYNQEEDSFYVHHDILLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVLGSARNSSISGPFGSRSSDTPMES
uniprot
proteins
function
FUNCTION: Chromatin-associated factor that regulates transcription (PubMed:29065309). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309). Regulates the epigenetic status of rDNA (PubMed:29065309). {ECO:0000269|PubMed:29065309}.
uniprot
proteins
mass_dalton
55828
uniprot
proteins
protein_family
WD repeat PWP1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17487921
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
29065309
uniprot
proteins
pubmed
7828893
uniprot
proteins
sequence_length
501
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:7828893}. Nucleus, nucleolus {ECO:0000269|PubMed:29065309}. Chromosome {ECO:0000269|PubMed:29065309}. Note=Associates with chromatin regions of rDNA. {ECO:0000269|PubMed:29065309}.
uniprot
proteins