Ncl
entrez
17975
canonical
uniprot
P09405
canonical
ensembl
ENSMUSG00000026234
resolver
ensp
ENSMUSP00000027438
resolver
ensp
ENSMUSP00000168661
resolver
enst
ENSMUST00000027438
resolver
genesymbol
Ncl
resolver
genesymbol_syn
Nuc
resolver
uniprot
Q548M9
resolver
uniprot
Q61991
resolver
uniprot
Q8BQD8
resolver
uniprot
Q99K50
resolver
uniprot_entry
NUCL_MOUSE
resolver
uniprot_sec
Q548M9
resolver
uniprot_sec
Q61991
resolver
uniprot_sec
Q8BQD8
resolver
uniprot_sec
Q99K50
resolver
amino_acid_sequence
MVKLAKAGKTHGEAKKMAPPPKEVEEDSEDEEMSEDEDDSSGEEEVVIPQKKGKKATTTPAKKVVVSQTKKAAVPTPAKKAAVTPGKKAVATPAKKNITPAKVIPTPGKKGAAQAKALVPTPGKKGAATPAKGAKNGKNAKKEDSDEDEDEEDEDDSDEDEDDEEEDEFEPPIVKGVKPAKAAPAAPASEDEEDDEDEDDEEDDDEEEEDDSEEEVMEITTAKGKKTPAKVVPMKAKSVAEEEDDEEEDEDDEDEDDEEEDDEDDDEEEEEEEPVKAAPGKRKKEMTKQKEAPEAKKQKVEGSEPTTPFNLFIGNLNPNKSVNELKFAISELFAKNDLAVVDVRTGTNRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAARTLLAKNLSFNITEDELKEVFEDAMEIRLVSQDGKSKGIAYIEFKSEADAEKNLEEKQGAEIDGRSVSLYYTGEKGQRQERTGKTSTWSGESKTLVLSNLSYSATKETLEEVFEKATFIKVPQNPHGKPKGYAFIEFASFEDAKEALNSCNKMEIEGRTIRLELQGSNSRSQPSKTLFVKGLSEDTTEETLKESFEGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDFKPQGKKTKFE
uniprot
proteins
function
FUNCTION: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats (By similarity). {ECO:0000250, ECO:0000269|PubMed:8065340}.
uniprot
proteins
mass_dalton
76723
uniprot
proteins
post_translational_modification
PTM: Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group.; PTM: Symmetrically methylated by PRMT5. {ECO:0000250|UniProtKB:P19338}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17622165
uniprot
proteins
pubmed
1860869
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19524510
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21474449
uniprot
proteins
pubmed
21518874
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24991885
uniprot
proteins
pubmed
28784777
uniprot
proteins
pubmed
2906027
uniprot
proteins
pubmed
3137346
uniprot
proteins
pubmed
8065340
uniprot
proteins
pubmed
9642267
uniprot
proteins
sequence_length
707
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:P19338}. Cytoplasm {ECO:0000250}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000250}.
uniprot
proteins