Batf3
entrez
381319
canonical
uniprot
Q9D275
canonical
ensembl
ENSMUSG00000026630
resolver
ensp
ENSMUSP00000027943
resolver
enst
ENSMUST00000027943
resolver
genesymbol
Batf3
resolver
uniprot_entry
BATF3_MOUSE
resolver
amino_acid_sequence
MSQGPPAVSVLQRSVDAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKADKLHEEHESLEQENSVLRREISKLKEELRHLSEVLKEHEKMCPLLLCPMNFVQLRSDPVASCLPR
uniprot
proteins
function
FUNCTION: AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens. {ECO:0000269|PubMed:19008445, ECO:0000269|PubMed:20351058, ECO:0000269|PubMed:21867928}.
uniprot
proteins
mass_dalton
13657
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19008445
uniprot
proteins
pubmed
20351058
uniprot
proteins
pubmed
21867927
uniprot
proteins
pubmed
21867928
uniprot
proteins
pubmed
22992524
uniprot
proteins
sequence_length
118
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
uniprot
proteins