Them5
entrez
66198
canonical
uniprot
Q9CQJ0
canonical
ensembl
ENSMUSG00000028148
resolver
ensp
ENSMUSP00000029794
resolver
genesymbol
Them5
resolver
genesymbol_syn
Acot15
resolver
uniprot
Q9CTI2
resolver
uniprot_entry
THEM5_MOUSE
resolver
uniprot_sec
Q9CTI2
resolver
amino_acid_sequence
MLRTSFQGVARLVRHKALYRSPCLLPRVHLASAFGSSTESLVARFCPEKTDLKDYALPNASWCSDMLSLYQEFLEKTKSGGWIKLPSFKSNRDHIQGLKLPFGLETASDKQDWRLFTRSIQLEGQGYEYVIFFHPSEKKSVCLFQPGPYLEGAPGFAHGGSLAALMDETYSKTAYLAGEGLFTLSLNIKFKNLIPVGSLAVLDIQVEKIEDQKLYMSCIAQSRDKQTVYAKSSGVFLQLQLEEQSQEQ
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
function
FUNCTION: Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters (By similarity). Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin (PubMed:22586271). Required for normal mitochondrial function (PubMed:22586271). {ECO:0000250|UniProtKB:Q8N1Q8, ECO:0000269|PubMed:22586271}.
uniprot
proteins
mass_dalton
27865
uniprot
proteins
protein_family
THEM4/THEM5 thioesterase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
22586271
uniprot
proteins
sequence_length
248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q8N1Q8}.
uniprot
proteins