Prelid1
entrez
66494
canonical
uniprot
Q8R107
canonical
ensembl
ENSMUSG00000021486
resolver
ensp
ENSMUSP00000021942
resolver
enst
ENSMUST00000021942
resolver
genesymbol
Prelid1
resolver
genesymbol_syn
Preli
resolver
uniprot
Q3UCN0
resolver
uniprot
Q4QQJ9
resolver
uniprot
Q6PCZ5
resolver
uniprot
Q78IE2
resolver
uniprot
Q9D1F7
resolver
uniprot_entry
PRLD1_MOUSE
resolver
uniprot_sec
Q3UCN0
resolver
uniprot_sec
Q4QQJ9
resolver
uniprot_sec
Q6PCZ5
resolver
uniprot_sec
Q78IE2
resolver
uniprot_sec
Q9D1F7
resolver
amino_acid_sequence
MVKYFLGQSVLRSSWDQVFAAFWQRYPNPYSKHVLTEDIVHREVTPDQKLLSRRLLTKTNRMPRWAERLFPANVAHSVYILEDSIVDPQNQTMTTFTWNINHARLMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFGVSRAVQEFGLARFKSNVTKTMKGFEYILAKLQGEAPSKTLVETAKEAKEKAKETALAATEKAKDLANKAATKQQQRQLV
uniprot
proteins
function
FUNCTION: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs (By similarity). {ECO:0000250|UniProtKB:Q9Y255, ECO:0000269|PubMed:21364629}.
uniprot
proteins
mass_dalton
24960
uniprot
proteins
pubmed
14640972
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21364629
uniprot
proteins
sequence_length
217
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:14640972}. Mitochondrion intermembrane space {ECO:0000250|UniProtKB:Q9Y255}.
uniprot
proteins