TLX2
entrez
3196
canonical
uniprot
O43763
canonical
ensembl
ENSG00000115297
resolver
ensp
ENSP00000233638
resolver
enst
ENST00000233638
resolver
genesymbol
TLX2
resolver
genesymbol_syn
HOX11L1
resolver
genesymbol_syn
NCX
resolver
hgnc
HGNC:5057
resolver
uniprot
Q9UD56
resolver
uniprot
Q9UQ48
resolver
uniprot_entry
TLX2_HUMAN
resolver
uniprot_sec
Q9UD56
resolver
uniprot_sec
Q9UQ48
resolver
amino_acid_sequence
MEPGMLGPHNLPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
uniprot
proteins
function
FUNCTION: Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
30251
uniprot
proteins
pubmed
10446220
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
20389279
uniprot
proteins
pubmed
7518789
uniprot
proteins
sequence_length
284
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins