KRTAP12-3
entrez
386683
canonical
uniprot
P60328
canonical
ensembl
ENSG00000205439
resolver
ensp
ENSP00000381005
resolver
enst
ENST00000397907
resolver
genesymbol
KRTAP12-3
resolver
genesymbol_syn
KAP12.3
resolver
genesymbol_syn
KRTAP12.3
resolver
hgnc
HGNC:20531
resolver
uniprot_entry
KR123_HUMAN
resolver
amino_acid_sequence
MCHTSCSPACQPTCCIHSPCQASCYVPVSCQSSVCMPVSCTRIVCVAPSCQPSVCVPVSCRPIIYVTPSCQSSGCCQPPCTTALCRPISCSTPSCC
uniprot
proteins
function
FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
uniprot
proteins
mass_dalton
9947
uniprot
proteins
protein_family
KRTAP type 12 family
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
14962103
uniprot
proteins
pubmed
15028290
uniprot
proteins
sequence_length
96
uniprot
proteins