CNEP1R1
entrez
255919
canonical
uniprot
Q8N9A8
canonical
ensembl
ENSG00000205423
resolver
ensp
ENSP00000394224
resolver
ensp
ENSP00000405635
resolver
genesymbol
CNEP1R1
resolver
genesymbol_syn
C16orf69
resolver
genesymbol_syn
TMEM188
resolver
hgnc
HGNC:26759
resolver
uniprot
Q4G1A9
resolver
uniprot
Q5H9V0
resolver
uniprot
Q8NE06
resolver
uniprot_entry
NEPR1_HUMAN
resolver
uniprot_sec
Q4G1A9
resolver
uniprot_sec
Q5H9V0
resolver
uniprot_sec
Q8NE06
resolver
amino_acid_sequence
MNSLEQAEDLKAFERRLTEYIHCLQPATGRWRMLLIVVSVCTATGAWNWLIDPETQKVSFFTSLWNHPFFTISCITLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHVQ
uniprot
proteins
function
FUNCTION: Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. {ECO:0000269|PubMed:22134922}.
uniprot
proteins
mass_dalton
14267
uniprot
proteins
protein_family
CNEP1R1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
22134922
uniprot
proteins
pubmed
22814378
uniprot
proteins
sequence_length
125
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000269|PubMed:22134922}; Multi-pass membrane protein {ECO:0000269|PubMed:22134922}. Cytoplasm {ECO:0000269|PubMed:22134922}. Note=Filamentous pattern in the cytoplasm.
uniprot
proteins
transmembrane_region
TRANSMEM 33..53; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 65..85; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins