CEACAM4
entrez
1089
canonical
uniprot
O75871
canonical
ensembl
ENSG00000105352
resolver
ensembl
ENSG00000274131
resolver
ensp
ENSP00000221954
resolver
ensp
ENSP00000473018
resolver
ensp
ENSP00000481247
resolver
ensp
ENSP00000572965
resolver
ensp
ENSP00000698302
resolver
ensp
ENSP00000763287
resolver
enst
ENST00000221954
resolver
enst
ENST00000616476
resolver
genesymbol
CEACAM4
resolver
genesymbol_syn
CGM7
resolver
hgnc
HGNC:1816
resolver
uniprot
A0A077JIU5
resolver
uniprot
A0A077JJN3
resolver
uniprot
Q03715
resolver
uniprot
Q7LDZ7
resolver
uniprot_entry
A0A077JIU5_HUMAN
resolver
uniprot_entry
A0A077JJN3_HUMAN
resolver
uniprot_entry
CEAM4_HUMAN
resolver
uniprot_sec
Q03715
resolver
uniprot_sec
Q7LDZ7
resolver
amino_acid_sequence
MGPPSAAPRGGHRPWQGLLITASLLTFWHPPTTVQFTIEALPSSAAEGKDVLLLACNISETIQAYYWHKGKTAEGSPLIAGYITDIQANIPGAAYSGRETVYPNGSLLFQNITLEDAGSYTLRTINASYDSDQATGQLHVHQNNVPGLPVGAVAGIVTGVLVGVALVAALVCFLLLSRTGRASIQRDLREQPPPASTPGHGPSHRSTFSAPLPSPRTATPIYEELLYSDANIYCQIDHKADVVS
uniprot
proteins
function
FUNCTION: Granulocyte orphan receptor that acts as an trigger efficient phagocytosis of attached particles. {ECO:0000269|PubMed:25567962}.
uniprot
proteins
mass_dalton
25909
uniprot
proteins
mutagenesis
MUTAGEN 222; /note="Y->F: No internalization of bacteria; when associated with F-233."; /evidence="ECO:0000269|PubMed:25567962"; MUTAGEN 233; /note="Y->F: No internalization of bacteria; when associated with F-222."; /evidence="ECO:0000269|PubMed:25567962
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:2050678}.; PTM: The cytoplasmic ITAM-like sequence becomes tyrosine phosphorylated by SRC family PTKs upon ligand-mediated receptor clustering and allows to initiate phagocytosis of bound ligand. {ECO:0000269|PubMed:25567962}.
uniprot
proteins
protein_family
CEA family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
2050678
uniprot
proteins
pubmed
25567962
uniprot
proteins
sequence_length
244
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 156..176; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins