Sox10
entrez
29361
canonical
uniprot
O55170
canonical
ensembl
ENSRNOG00000011305
resolver
ensembl
ENSRNOG00055031334
resolver
ensembl
ENSRNOG00060019038
resolver
ensembl
ENSRNOG00065033091
resolver
ensp
ENSRNOP00000015283
resolver
ensp
ENSRNOP00055044884
resolver
ensp
ENSRNOP00060026908
resolver
ensp
ENSRNOP00065046871
resolver
enst
ENSRNOT00000015283
resolver
enst
ENSRNOT00055054279
resolver
enst
ENSRNOT00060032911
resolver
enst
ENSRNOT00065056930
resolver
genesymbol
Sox10
resolver
uniprot_entry
SOX10_RAT
resolver
amino_acid_sequence
MAEEQDLSEVELSPVGSEEPRCLSPSSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGETDQGGAAAIQAHYKSAHLDHRHPEEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSLGEGGKPHIDFGNVDIGEISHEVMSNMETFDVTELDQYLPPNGHPGHVGSYSAAGYGLSSALAVASGHSAWISKPPGVALPTVSPPAVDAKAQVKTETTGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHAGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
uniprot
proteins
function
FUNCTION: Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). Transcriptional activator of MBP, via binding to the gene promoter (PubMed:26525805). {ECO:0000250|UniProtKB:P56693, ECO:0000250|UniProtKB:Q04888, ECO:0000269|PubMed:26525805}.
uniprot
proteins
mass_dalton
50039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
26525805
uniprot
proteins
pubmed
9412504
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q04888}. Nucleus {ECO:0000269|PubMed:9412504}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q04888}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q04888}; Cytoplasmic side {ECO:0000250|UniProtKB:Q04888}.
uniprot
proteins