Rasgef1b
entrez
320292
canonical
uniprot
Q8JZL7
canonical
ensembl
ENSMUSG00000089809
resolver
ensp
ENSMUSP00000031276
resolver
ensp
ENSMUSP00000129652
resolver
genesymbol
Rasgef1b
resolver
genesymbol_syn
Gpig4
resolver
uniprot
F5H8M5
resolver
uniprot
Q3UE12
resolver
uniprot
Q8C189
resolver
uniprot_entry
RGF1B_MOUSE
resolver
uniprot_sec
F5H8M5
resolver
uniprot_sec
Q3UE12
resolver
uniprot_sec
Q8C189
resolver
amino_acid_sequence
MPQTPPFSAMFDSSGYNRNLYQSAEDSCGGLYYHDNNLLSGSLEALIQHLVPNVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCVEHQRLSEGDGDKNQMRKIAPKILQLLTEWTETFPYDFRDERMMRNLKDLAHRMASGEEQTYRKNVQQMMQCLIRKLAALSQYEEVLAKLSSTATDRLTVLKTKPQSIQRDIMTVCSDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCVNRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKVLQYLLSVPVFSEDALYLASYESEGPENNIEKDRWKSLRSSLLGRV
uniprot
proteins
function
FUNCTION: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro). {ECO:0000269|PubMed:20090772}.
uniprot
proteins
mass_dalton
55273
uniprot
proteins
pubmed
12488504
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20090772
uniprot
proteins
sequence_length
473
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Early endosome {ECO:0000269|PubMed:20090772}. Late endosome {ECO:0000269|PubMed:20090772}. Midbody {ECO:0000250}. Note=Localizes to midbody at telophase (By similarity). May shuttle between early and late endosomes. Does not colocalize with lysosomal markers. {ECO:0000250}.
uniprot
proteins