PAOX
entrez
196743
canonical
uniprot
Q6QHF9
canonical
ensembl
ENSG00000148832
resolver
ensp
ENSP00000278060
resolver
ensp
ENSP00000349847
resolver
ensp
ENSP00000435514
resolver
genesymbol
PAOX
resolver
genesymbol_syn
PAO
resolver
hgnc
HGNC:20837
resolver
uniprot
D3DXI6
resolver
uniprot
Q5VWY0
resolver
uniprot
Q6QHF5
resolver
uniprot
Q6QHF6
resolver
uniprot
Q6QHF7
resolver
uniprot
Q6QHF8
resolver
uniprot
Q6QHG0
resolver
uniprot
Q6QHG1
resolver
uniprot
Q6QHG2
resolver
uniprot
Q6QHG3
resolver
uniprot
Q6QHG4
resolver
uniprot
Q6QHG5
resolver
uniprot
Q6QHG6
resolver
uniprot
Q86WP9
resolver
uniprot
Q8N555
resolver
uniprot
Q8NCX3
resolver
uniprot_entry
PAOX_HUMAN
resolver
uniprot_sec
D3DXI6
resolver
uniprot_sec
Q5VWY0
resolver
uniprot_sec
Q6QHF5
resolver
uniprot_sec
Q6QHF6
resolver
uniprot_sec
Q6QHF7
resolver
uniprot_sec
Q6QHF8
resolver
uniprot_sec
Q6QHG0
resolver
uniprot_sec
Q6QHG1
resolver
uniprot_sec
Q6QHG2
resolver
uniprot_sec
Q6QHG3
resolver
uniprot_sec
Q6QHG4
resolver
uniprot_sec
Q6QHG5
resolver
uniprot_sec
Q6QHG6
resolver
uniprot_sec
Q86WP9
resolver
uniprot_sec
Q8N555
resolver
uniprot_sec
Q8NCX3
resolver
amino_acid_sequence
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL
uniprot
proteins
ec_number
1.5.3.13
uniprot
proteins
function
FUNCTION: Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). {ECO:0000269|PubMed:12477380}.
uniprot
proteins
mass_dalton
55513
uniprot
proteins
pathway_participation
PATHWAY: Amine and polyamine metabolism; spermine metabolism. {ECO:0000269|PubMed:12477380}.
uniprot
proteins
protein_family
Flavin monoamine oxidase family
uniprot
proteins
pubmed
12477380
uniprot
proteins
pubmed
12660232
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
22814378
uniprot
proteins
sequence_length
511
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000250}. Cytoplasm {ECO:0000250}.
uniprot
proteins