MPG
entrez
4350
canonical
uniprot
P29372
canonical
ensembl
ENSG00000103152
resolver
ensp
ENSP00000219431
resolver
ensp
ENSP00000348809
resolver
ensp
ENSP00000380918
resolver
genesymbol
MPG
resolver
genesymbol_syn
AAG
resolver
genesymbol_syn
ANPG
resolver
genesymbol_syn
MID1
resolver
hgnc
HGNC:7211
resolver
uniprot
G5E9E2
resolver
uniprot
Q13770
resolver
uniprot
Q15275
resolver
uniprot
Q15961
resolver
uniprot
Q5J9I4
resolver
uniprot
Q96BZ6
resolver
uniprot
Q96S33
resolver
uniprot
Q9NNX5
resolver
uniprot_entry
3MG_HUMAN
resolver
uniprot_sec
G5E9E2
resolver
uniprot_sec
Q13770
resolver
uniprot_sec
Q15275
resolver
uniprot_sec
Q15961
resolver
uniprot_sec
Q5J9I4
resolver
uniprot_sec
Q96BZ6
resolver
uniprot_sec
Q96S33
resolver
uniprot_sec
Q9NNX5
resolver
activity_regulation
ACTIVITY REGULATION: Binding to SSBP1 in mitochondria inhibits glycosylase activity in the context of a single-stranded DNA (ssDNA), but not a double-stranded DNA (dsDNA) substrates. {ECO:0000269|PubMed:23290262}.
uniprot
proteins
amino_acid_sequence
MVTPALQMKKPKQFCRRMGQKKQRPARAGQPHSSSDAAQAPAEQPHSSSDAAQAPCPRERCLGPPTTPGPYRSIYFSSPKGHLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYIIYGMYFCMNISSQGDGACVLLRALEPLEGLETMRQLRSTLRKGTASRVLKDRELCSGPSKLCQALAINKSFDQRDLAQDEAVWLERGPLEPSEPAVVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQDTQA
uniprot
proteins
ec_number
3.2.2.21
uniprot
proteins
function
FUNCTION: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
uniprot
proteins
mass_dalton
32869
uniprot
proteins
protein_family
DNA glycosylase MPG family
uniprot
proteins
pubmed
11157797
uniprot
proteins
pubmed
14555760
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
1645538
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
1874728
uniprot
proteins
pubmed
1924375
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23290262
uniprot
proteins
pubmed
8318735
uniprot
proteins
pubmed
8475094
uniprot
proteins
pubmed
9790531
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23290262}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:23290262}. Nucleus {ECO:0000269|PubMed:23290262}.
uniprot
proteins