Fabp5
entrez
140868
canonical
uniprot
P55053
canonical
ensembl
ENSRNOG00000049075
resolver
ensembl
ENSRNOG00055001808
resolver
ensembl
ENSRNOG00060001912
resolver
ensembl
ENSRNOG00065013312
resolver
ensp
ENSRNOP00000064809
resolver
ensp
ENSRNOP00055002201
resolver
ensp
ENSRNOP00060001949
resolver
ensp
ENSRNOP00065016957
resolver
enst
ENSRNOT00000075493
resolver
enst
ENSRNOT00055002924
resolver
enst
ENSRNOT00060002960
resolver
enst
ENSRNOT00065021881
resolver
genesymbol
Fabp5
resolver
uniprot
P97757
resolver
uniprot_entry
FABP5_RAT
resolver
uniprot_sec
P97757
resolver
amino_acid_sequence
MASLKDLEGKWRLVESHGFEDYMKELGVGLALRKMGAMAKPDCIITLDGNNLTVKTESTVKTTVFSCTLGEKFDETTADGRKTETVCTFTDGALVQHQKWEGKESTITRKLKDGKMVVECVMNNAICTRVYEKVQ
uniprot
proteins
function
FUNCTION: Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (By similarity). Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity). {ECO:0000250|UniProtKB:Q01469, ECO:0000250|UniProtKB:Q05816}.
uniprot
proteins
mass_dalton
15059
uniprot
proteins
protein_family
Calycin superfamily
uniprot
proteins
protein_family
Fatty-acid binding protein (FABP) family
uniprot
proteins
pubmed
10965032
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
7607553
uniprot
proteins
pubmed
8166694
uniprot
proteins
pubmed
8723767
uniprot
proteins
sequence_length
135
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q05816}. Nucleus {ECO:0000250|UniProtKB:Q01469}. Synapse {ECO:0000250|UniProtKB:Q05816}. Postsynaptic density {ECO:0000250|UniProtKB:Q05816}. Secreted {ECO:0000250|UniProtKB:Q05816}. Note=Localizes primarily to the cytoplasm. Upon certain ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into nucleus (By similarity). Secreted by astrocytes, but not by neurons (By similarity). {ECO:0000250|UniProtKB:Q01469, ECO:0000250|UniProtKB:Q05816}.
uniprot
proteins