Tctn2
entrez
689779
canonical
uniprot
Q3B7D3
canonical
ensembl
ENSRNOG00000088480
resolver
ensp
ENSRNOP00000072568
resolver
enst
ENSRNOT00000084553
resolver
genesymbol
Tctn2
resolver
genesymbol_syn
Tect2
resolver
uniprot_entry
TECT2_RAT
resolver
amino_acid_sequence
MGSLSPLSFLWGLLLLQGVLRPLRGDPVFIPPFIRMSSPEVRASLVGGSEDVTVSLTPLQIKEGVLPVPTCGGLRNETGDWNLTVSPQANMLEVTVRWKRGLDWCSPDETASFSEAPCIVQTLLVSASHNASCLAHLLIQVEIYPNTSVTHNASENMTVIPNQVYQPLGPCPCDLTAKACDIRCCCDQDCQPELRELFERFCFSGVFGGYVSPPSHHRCAARTTHQTPDWFPFLCVQSPPSTSPFLGHFYHGAISPRHSPGFETHSHLDLRDFFADASYKQGDPIMTTNGYFTIPQASLAGQCLQDAPVAFLRNFHSVCTTDLEVQERDRLIPEDMRIRTTGGLVTPTVTYEEATDLDKLITSPDTILSAGSAPRNVTVEEHYVFRWQNNSISSLDITIIRAEINAHQRGTMTQRFTVKFLSPNSGGEKEFSGNPGYQLGKPVRALHTDGMNVTTLHLWQPAGRGLCTSAALRPVLFGEDASSGCLLEVGIKENCTQLRENVLQRLDLLIQATHVARRGNSDYGDLSDGWLEVIRVDAPDAGADLPLSSANGMCPEVPTHVTIRILTAEAGAVEGEAQREILAVETRFSTVTWQYQCGLTCEEDKADLLPLSASVKFINIPAQMPRPTRFQINFTEYDCTRNELCWPQLLYPLTQYYQGEPRPQCVAKGLMLLSLLMLAILLRHPWVGMCKAWSSASIQH
uniprot
proteins
function
FUNCTION: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
77301
uniprot
proteins
protein_family
Tectonic family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
700
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 666..682; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins