CD1B
entrez
910
canonical
uniprot
P29016
canonical
ensembl
ENSG00000158485
resolver
ensp
ENSP00000357150
resolver
ensp
ENSP00000572943
resolver
genesymbol
CD1B
resolver
hgnc
HGNC:1635
resolver
uniprot
Q5TDK9
resolver
uniprot
Q5TDL0
resolver
uniprot
Q9UMM2
resolver
uniprot_entry
CD1B_HUMAN
resolver
uniprot_sec
Q5TDK9
resolver
uniprot_sec
Q5TDL0
resolver
uniprot_sec
Q9UMM2
resolver
amino_acid_sequence
MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP
uniprot
proteins
function
FUNCTION: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:10981968, ECO:0000269|PubMed:14716313}.
uniprot
proteins
mass_dalton
36939
uniprot
proteins
mutagenesis
MUTAGEN 329..330; /note="YQ->AA: Strongly reduced internalization and trafficking to endosomes."; /evidence="ECO:0000269|PubMed:10981968
uniprot
proteins
pubmed
10899914
uniprot
proteins
pubmed
10981968
uniprot
proteins
pubmed
12118248
uniprot
proteins
pubmed
14716313
uniprot
proteins
pubmed
14764708
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16874306
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
2447586
uniprot
proteins
pubmed
2701945
uniprot
proteins
pubmed
3097645
uniprot
proteins
sequence_length
333
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10899914, ECO:0000269|PubMed:10981968, ECO:0000269|PubMed:14716313}; Single-pass type I membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:10899914, ECO:0000269|PubMed:14716313}; Single-pass type I membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:10899914, ECO:0000269|PubMed:10981968, ECO:0000269|PubMed:14716313}; Single-pass type I membrane protein {ECO:0000255}. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. {ECO:0000269|PubMed:10899914, ECO:0000269|PubMed:10981968, ECO:0000269|PubMed:14716313}.
uniprot
proteins
transmembrane_region
TRANSMEM 304..324; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins