Apcdd1
entrez
494504
canonical
uniprot
Q3U128
canonical
ensembl
ENSMUSG00000071847
resolver
ensp
ENSMUSP00000094302
resolver
ensp
ENSMUSP00000157539
resolver
enst
ENSMUST00000096554
resolver
enst
ENSMUST00000236135
resolver
genesymbol
Apcdd1
resolver
genesymbol_syn
Drapc1
resolver
uniprot
B2RUN4
resolver
uniprot
Q3TA99
resolver
uniprot_entry
APCD1_MOUSE
resolver
uniprot_sec
B2RUN4
resolver
uniprot_sec
Q3TA99
resolver
amino_acid_sequence
MSRVRRLLLGYLFPALLLHGLGEGSALLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLHNGARITVQMPPTIEGHWVSTGCEVRSGPEFMTRSYRFYNNNTFKAYQFYYGSNRCTNPTYTLIIRGKIRLRQASWIIRGGTEADYQLHGVQVICHTEAVAEQLSRLVNRTCPGFLAPGGPWVQDVAYDLWQEESNHECTKAVNFAMHELQLIRVEKQYPHHSLDHLVEELFLGDIHTDATQRVFYRPSSYQPPLQNAKNHNHACIACRIIFRSDEHHPPILPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFTIYARGRYSRGVLSSKVMGGTEFVFKVNHMKVTPMDAATASLLNVFSGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHTEYEIFKMEQDTRGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASSSPRAEELLEDSQGHLYGRAAGRTAGSLLLPAFVSLWTLPHWRILR
uniprot
proteins
function
FUNCTION: Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
58638
uniprot
proteins
post_translational_modification
PTM: N-Glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
APCDD1 family
uniprot
proteins
pubmed
15465500
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
514
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 493..513; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins