Dok5
entrez
76829
canonical
uniprot
Q91ZM9
canonical
ensembl
ENSMUSG00000027560
resolver
ensp
ENSMUSP00000029075
resolver
ensp
ENSMUSP00000297987
resolver
enst
ENSMUST00000029075
resolver
genesymbol
Dok5
resolver
uniprot
Q8BRI3
resolver
uniprot
Q9CSM6
resolver
uniprot_entry
DOK5_MOUSE
resolver
uniprot_sec
Q8BRI3
resolver
uniprot_sec
Q9CSM6
resolver
amino_acid_sequence
MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVTELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKKSERAASLSTVVPLPRSAYWQHITRQHSTGQLYHLQDVTSPLKLHRTETFPTYRSEH
uniprot
proteins
function
FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. {ECO:0000269|PubMed:11470823}.
uniprot
proteins
mass_dalton
35453
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues in response to insulin, IGF1 and GDNF. {ECO:0000250}.
uniprot
proteins
protein_family
DOK family
uniprot
proteins
protein_family
Type B subfamily
uniprot
proteins
pubmed
11470823
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
306
uniprot
proteins