Ppp1r14b
entrez
18938
canonical
uniprot
Q62084
canonical
ensembl
ENSMUSG00000056612
resolver
ensp
ENSMUSP00000064129
resolver
enst
ENSMUST00000070850
resolver
genesymbol
Ppp1r14b
resolver
genesymbol_syn
Png
resolver
uniprot
Q640Q7
resolver
uniprot_entry
PP14B_MOUSE
resolver
uniprot_sec
Q640Q7
resolver
amino_acid_sequence
MADSGPAGGAALAAPAPGPGSGSTGPRVYFQSPPGAAGEGPGGADDDGPVRRQGKVTVKYDRKELRKRLNLEEWILEQLTRLYDCQEEEIPELEIDVDELLDMESDDTRAARVKELLVDCYKPTEAFISGLLDKIRGMQKLSTPQKK
uniprot
proteins
function
FUNCTION: Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated. {ECO:0000269|PubMed:10606530, ECO:0000269|PubMed:12144526}.
uniprot
proteins
mass_dalton
15957
uniprot
proteins
mutagenesis
MUTAGEN 57; /note="T->A: Abolishes phosphorylation and strongly reduces inhibitory activity."; /evidence="ECO:0000269|PubMed:10606530
uniprot
proteins
post_translational_modification
PTM: Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro). {ECO:0000269|PubMed:10606530, ECO:0000269|PubMed:12144526}.
uniprot
proteins
protein_family
PP1 inhibitor family
uniprot
proteins
pubmed
10606530
uniprot
proteins
pubmed
12144526
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8670283
uniprot
proteins
sequence_length
147
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins