FCGR3B
entrez
2215
canonical
uniprot
O75015
canonical
ensembl
ENSG00000162747
resolver
ensp
ENSP00000356941
resolver
ensp
ENSP00000394204
resolver
ensp
ENSP00000497461
resolver
ensp
ENSP00000578350
resolver
ensp
ENSP00000578351
resolver
enst
ENST00000367964
resolver
enst
ENST00000421702
resolver
enst
ENST00000650385
resolver
enst
ENST00000908291
resolver
genesymbol
FCGR3B
resolver
genesymbol_syn
CD16B
resolver
genesymbol_syn
FCG3
resolver
genesymbol_syn
FCGR3
resolver
genesymbol_syn
IGFR3
resolver
hgnc
HGNC:3620
resolver
uniprot
A0A3B3ISU3
resolver
uniprot
H0Y4U3
resolver
uniprot_entry
A0A3B3ISU3_HUMAN
resolver
uniprot_entry
FCG3B_HUMAN
resolver
uniprot_entry
H0Y4U3_HUMAN
resolver
amino_acid_sequence
MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNENLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVSFCLVMVLLFAVDTGLYFSVKTNI
uniprot
proteins
function
FUNCTION: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
uniprot
proteins
mass_dalton
26243
uniprot
proteins
mutagenesis
MUTAGEN 203; /note="S->P: Abolishes membrane anchoring via glycosylphosphatidylinositol."; /evidence="ECO:0000269|PubMed:1825220"; MUTAGEN 203; /note="S->T,Y,A,D,K: Has no effect on membrane anchoring via glycosylphosphatidylinositol."; /evidence="ECO:0000269|PubMed:1825220
uniprot
proteins
post_translational_modification
PTM: Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3.; PTM: The soluble form is produced by a proteolytic cleavage.
uniprot
proteins
pubmed
10917521
uniprot
proteins
pubmed
11021536
uniprot
proteins
pubmed
15245367
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
1825220
uniprot
proteins
pubmed
2521732
uniprot
proteins
pubmed
2525780
uniprot
proteins
pubmed
2526846
uniprot
proteins
pubmed
28566370
uniprot
proteins
pubmed
2967436
uniprot
proteins
pubmed
7836402
uniprot
proteins
pubmed
9028335
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:1825220}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:1825220}. Secreted. Note=Secreted after cleavage.
uniprot
proteins