ING3
entrez
54556
canonical
uniprot
Q9NXR8
canonical
ensembl
ENSG00000071243
resolver
ensp
ENSP00000320566
resolver
ensp
ENSP00000341697
resolver
ensp
ENSP00000771089
resolver
ensp
ENSP00000780288
resolver
genesymbol
ING3
resolver
hgnc
HGNC:14587
resolver
uniprot
A8K790
resolver
uniprot
B7ZKQ7
resolver
uniprot
O60394
resolver
uniprot
Q567P3
resolver
uniprot
Q6GMT3
resolver
uniprot
Q7Z762
resolver
uniprot
Q969G0
resolver
uniprot
Q96DT4
resolver
uniprot
Q9HC99
resolver
uniprot
Q9P081
resolver
uniprot_entry
B7ZKQ7_HUMAN
resolver
uniprot_entry
ING3_HUMAN
resolver
uniprot_sec
A8K790
resolver
uniprot_sec
O60394
resolver
uniprot_sec
Q567P3
resolver
uniprot_sec
Q6GMT3
resolver
uniprot_sec
Q7Z762
resolver
uniprot_sec
Q969G0
resolver
uniprot_sec
Q96DT4
resolver
uniprot_sec
Q9HC99
resolver
uniprot_sec
Q9P081
resolver
amino_acid_sequence
MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK
uniprot
proteins
disease_involvement
DISEASE: Squamous cell carcinoma of the head and neck (HNSCC) [MIM:275355]: A non-melanoma skin cancer affecting the head and neck. The hallmark of cutaneous SCC is malignant transformation of normal epidermal keratinocytes. {ECO:0000269|PubMed:12080476}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome. {ECO:0000269|PubMed:12545155, ECO:0000269|PubMed:14966270, ECO:0000269|PubMed:24463511}.
uniprot
proteins
mass_dalton
46743
uniprot
proteins
protein_family
ING family
uniprot
proteins
pubmed
12080476
uniprot
proteins
pubmed
12545155
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
12963728
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14966270
uniprot
proteins
pubmed
15196461
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16387653
uniprot
proteins
pubmed
16728974
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19154204
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
24463511
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25772364
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
418
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins