Adarb2
entrez
117088
canonical
uniprot
P97616
canonical
ensembl
ENSRNOG00000030775
resolver
ensp
ENSRNOP00000047468
resolver
ensp
ENSRNOP00000110240
resolver
enst
ENSRNOT00000157779
resolver
genesymbol
Adarb2
resolver
genesymbol_syn
Adar3
resolver
genesymbol_syn
Red2
resolver
uniprot
A0ABK0M5S9
resolver
uniprot_entry
A0ABK0M5S9_RAT
resolver
uniprot_entry
RED2_RAT
resolver
amino_acid_sequence
MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLAPFKYLSPGTTNTEDEDNLSTSSAEVKENRNVSNLGTRPLPPGDWARGGSTPSVKRKRPLEEGNGGHFCKLQLIWKKLSWSMTPKNALVQLHELKPGLQYRMVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAEMALKSFVQFPNAFQAHLAMGSSTSPCTDFTSDQADFPDTLFKEFEPSSRNEDFPGCCPVDTEFLSSAYRRGRLLYHTLDLMGQALPDRSRLAPGALGERNPVVVLNELRSGLRYVCLSETAEKPRVKSFVMAVCVDGRTFEGSGRSKKLAKGQAAQAALQALFDIRLPGHIPSRSKSNLLPQDFADSVSQLVTQKFRELTVGLTSVYARHKTLAGIVMTKGLDTKQAQVIVLSSGTKCISGEHISDQGLVVNDCHAEIVARRAFLHFLYTQLELHLSKHQEDPERSIFIRVKEGGYRLRENILFHLYVSTSPCGDARLNSPYEITIDLNSSKHIVRKFRGHLRTKIESGEGTVPVRGPSAVQTWDGILLGEQLVTMSCTDKIASWNVLGLQGALLCHFIEPVYLHSIIVGSLHHTGHLARVMSHRMEGIGQLPASYRQNRPLLSGVSNAEARQPGKSPHFSANWVVGSADLEIINATTGKRSCGGSSRLCKHVFSARWARLHGRLSTRIPGHGDTPSMYCEAKRGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQDQFLLSL
uniprot
proteins
function
FUNCTION: Single- and double-stranded RNA-binding protein that interferes with the RNA editing activities of ADAR/ADAR1 and ADARB1/ADAR2. Likely competes with these proteins for target binding, repressing RNA editing across the transcriptome (PubMed:8943218). Additionally, it binds and stabilizes specific mRNAs and regulates the expression of proteins such as MAVS, DUSP1, and EGR1, independently of RNA editing mechanisms (By similarity). {ECO:0000250|UniProtKB:Q9NS39, ECO:0000269|PubMed:8943218}.
uniprot
proteins
mass_dalton
82227
uniprot
proteins
pubmed
8943218
uniprot
proteins
sequence_length
746
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NS39}.
uniprot
proteins