TUSC2
entrez
11334
canonical
uniprot
O75896
canonical
ensembl
ENSG00000114383
resolver
ensp
ENSP00000232496
resolver
enst
ENST00000232496
resolver
genesymbol
TUSC2
resolver
genesymbol_syn
C3orf11
resolver
genesymbol_syn
FUS1
resolver
genesymbol_syn
LGCC
resolver
genesymbol_syn
PDAP2
resolver
hgnc
HGNC:17034
resolver
uniprot
B2R4Y9
resolver
uniprot_entry
TUSC2_HUMAN
resolver
uniprot_sec
B2R4Y9
resolver
amino_acid_sequence
MGASGSKARGLWPFASAAGGGGSEAAGAEQALVRPRGRAVPPFVFTRRGSMFYDEDGDLAHEFYEETIVTKNGQKRAKLRRVHKNLIPQGIVKLDHPRIHVDFPVILYEV
uniprot
proteins
function
FUNCTION: May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
uniprot
proteins
mass_dalton
12074
uniprot
proteins
post_translational_modification
PTM: Myristoylation is required for tumor suppressor activity. {ECO:0000269|PubMed:15126327}.
uniprot
proteins
protein_family
TUSC2 family
uniprot
proteins
pubmed
11593436
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15126327
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
110
uniprot
proteins