Setd6
entrez
291844
canonical
uniprot
D3ZSK5
canonical
ensembl
ENSRNOG00000012447
resolver
ensembl
ENSRNOG00055021414
resolver
ensembl
ENSRNOG00060013884
resolver
ensembl
ENSRNOG00065011196
resolver
ensp
ENSRNOP00000112070
resolver
ensp
ENSRNOP00055029732
resolver
ensp
ENSRNOP00060018875
resolver
ensp
ENSRNOP00065013808
resolver
enst
ENSRNOT00055036595
resolver
enst
ENSRNOT00060023723
resolver
enst
ENSRNOT00065018124
resolver
genesymbol
Setd6
resolver
uniprot_entry
SETD6_RAT
resolver
amino_acid_sequence
MAAPAKRARVSDASPLAAPCPVPRAAARVPLPLPAGPSGHEPESDAVAGFLRWCTRVGLELSPKVLVSRQGTVAGYGMVARESVQPGELLFAVPRSALLSPHTCSISDLLERERGALQSLSGWVPLLLALLHELQAPASPWSPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPTVRSLELYRQLVALVMAYSFQEPLEEEEDEKEPNSPLMVPAADILNHIANHNANLEYSAEYLRMVATQPILKGHEIFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVAVREAALQGTEDETERLLLCERWDFLCKQELVGEEGAFVIGREEVLTEEELATTLKVLCMPAEEFRDYKERAGWGEEETEDGSLAITNIPKLQESWKRLLRDSVLLTLQTYATDLKTEQDLLSNKEVYAKLSWREQQALQVRYGQKMILHRLLELTS
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (By similarity). Required for the maintenance of embryonic stem cell self-renewal (By similarity). Methylates PAK4. {ECO:0000250|UniProtKB:Q8TBK2, ECO:0000250|UniProtKB:Q9CWY3}.
uniprot
proteins
mass_dalton
53362
uniprot
proteins
post_translational_modification
PTM: Automethylated. {ECO:0000250|UniProtKB:Q8TBK2}.
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
Histone-lysine methyltransferase family
uniprot
proteins
protein_family
SETD6 subfamily
uniprot
proteins
sequence_length
474
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8TBK2}.
uniprot
proteins