ARHGEF10
entrez
9639
canonical
uniprot
O15013
canonical
ensembl
ENSG00000104728
resolver
ensembl
ENSG00000274726
resolver
ensp
ENSP00000340297
resolver
ensp
ENSP00000381571
resolver
ensp
ENSP00000427768
resolver
ensp
ENSP00000427909
resolver
ensp
ENSP00000431012
resolver
ensp
ENSP00000532922
resolver
ensp
ENSP00000532923
resolver
ensp
ENSP00000532924
resolver
ensp
ENSP00000532925
resolver
ensp
ENSP00000596789
resolver
ensp
ENSP00000596791
resolver
ensp
ENSP00000596795
resolver
genesymbol
ARHGEF10
resolver
genesymbol_syn
KIAA0294
resolver
hgnc
HGNC:14103
resolver
uniprot
O14665
resolver
uniprot
Q2KHR8
resolver
uniprot
Q68D55
resolver
uniprot
Q8IWD9
resolver
uniprot
Q8IY77
resolver
uniprot_entry
ARHGA_HUMAN
resolver
uniprot_sec
O14665
resolver
uniprot_sec
Q2KHR8
resolver
uniprot_sec
Q68D55
resolver
uniprot_sec
Q8IWD9
resolver
uniprot_sec
Q8IY77
resolver
amino_acid_sequence
MRPPGFLSRAPSLNRAERGIWSCSMDQREPLPPAPAENEMKYDTNNNEEEEGEQFDFDSGDEIPEADRQAPSAPETGGAGASEAPAPTGGEDGAGAETTPVAEPTKLVLPMKVNPYSVIDITPFQEDQPPTPVPSAEEENVGLHVPCGYLVPVPCGYAVPSNLPLLLPAYSSPVIICATSLDEEAETPEVTEDRQPNSLSSEEPPTSEDQVGREDSALARWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGDEGGNSSLEYGWSSSEFESYEEQSDSECKNGIPRSFLRSNHKKQLSHDLTRLKEHYEKKMRDLMASTVGVVEIQQLRQKHELKMQKLVKAAKDGTKDGLERTRAAVKRGRSFIRTKSLIAQDHRSSLEEEQNLFIDVDCKHPEAILTPMPEGLSQQQVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCHSLFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKQEQEASPDRTTLYSLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLSSGSRYLIRSDDMIETVYNDRGEIVKTKERRVFMLNDVLMCATVSSRPSHDSRVMSSQRYLLKWSVPLGHVDAIEYGSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPGQLYQDLQNLLHDLNVIGQITQLIGNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDKSGRPTFFTAVFNTFTPAIKESWVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLVGHMPVMVAKQQEFKIECAAYNPEPYLNNESQPDSFSTAHGFLWIGSCTHQMGQIAIVSFQNSTPKVIECFNVESRILCMLYVPVEEKRREPGAPPDPETPAVRASDVPTICVGTEEGSISIYKSSQGSKKVRLQHFFTPEKSTVMSLACTSQSLYAGLVNGAVASYARAPDGSWDSEPQKVIKLGVLPVRSLLMMEDTLWAASGGQVFIISVETHAVEGQLEAHQEEGMVISHMAVSGVGIWIAFTSGSTLRLFHTETLKHLQDINIATPVHNMLPGHQRLSVTSLLVCHGLLMVGTSLGVLVALPVPRLQGIPKVTGRGMVSYHAHNSPVKFIVLATALHEKDKDKSRDSLAPGPEPQDEDQKDALPSGGAGSSLSQGDPDAAIWLGDSLGSMTQKSDLSSSSGSLSLSHGSSSLEHRSEDSTIYDLLKDPVSLRSKARRAKKAKASSALVVCGGQGHRRVHRKARQPHQEELAPTVMVWQIPLLNI
uniprot
proteins
disease_involvement
DISEASE: Slowed nerve conduction velocity (SNCV) [MIM:608236]: Affected individuals present a reduction in nerve conduction velocities without any clinical signs of peripheral or central nervous system dysfunction. SNCV inheritance is autosomal dominant. {ECO:0000269|PubMed:14508709}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: May play a role in developmental myelination of peripheral nerves. {ECO:0000269|PubMed:14508709}.
uniprot
proteins
mass_dalton
151612
uniprot
proteins
mutagenesis
MUTAGEN 1338; /note="Q->R: Abolishes methylation by N6AMT1."; /evidence="ECO:0000269|PubMed:26797129
uniprot
proteins
post_translational_modification
PTM: Methylated at Gln-1338 by N6AMT1. {ECO:0000269|PubMed:26797129}.
uniprot
proteins
pubmed
12168954
uniprot
proteins
pubmed
14508709
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24627108
uniprot
proteins
pubmed
26797129
uniprot
proteins
pubmed
9205841
uniprot
proteins
pubmed
9314494
uniprot
proteins
sequence_length
1369
uniprot
proteins