CST4
entrez
1472
canonical
uniprot
P01036
canonical
ensembl
ENSG00000101441
resolver
ensp
ENSP00000217423
resolver
enst
ENST00000217423
resolver
genesymbol
CST4
resolver
hgnc
HGNC:2476
resolver
uniprot
Q9UBI5
resolver
uniprot
Q9UCS9
resolver
uniprot_entry
CYTS_HUMAN
resolver
uniprot_sec
Q9UBI5
resolver
uniprot_sec
Q9UCS9
resolver
amino_acid_sequence
MARPLCTLLLLMATLAGALASSSKEENRIIPGGIYDADLNDEWVQRALHFAISEYNKATEDEYYRRPLQVLRAREQTFGGVNYFFDVEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFEIYEVPWEDRMSLVNSRCQEA
uniprot
proteins
function
FUNCTION: This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
uniprot
proteins
mass_dalton
16214
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at both its N- and C-terminal regions. {ECO:0000269|PubMed:1741693, ECO:0000269|PubMed:1747107, ECO:0000269|PubMed:1778989, ECO:0000269|PubMed:1898055, ECO:0000269|PubMed:20189825}.
uniprot
proteins
protein_family
Cystatin family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
1334620
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
1741693
uniprot
proteins
pubmed
1747107
uniprot
proteins
pubmed
1778989
uniprot
proteins
pubmed
1898055
uniprot
proteins
pubmed
1898352
uniprot
proteins
pubmed
20189825
uniprot
proteins
pubmed
25946035
uniprot
proteins
pubmed
3496880
uniprot
proteins
pubmed
6394600
uniprot
proteins
pubmed
6501254
uniprot
proteins
sequence_length
141
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:20189825}.
uniprot
proteins