DET1
entrez
55070
canonical
uniprot
Q7L5Y6
canonical
ensembl
ENSG00000140543
resolver
ensembl
ENSG00000173867
resolver
ensp
ENSP00000268148
resolver
ensp
ENSP00000456340
resolver
ensp
ENSP00000565663
resolver
genesymbol
DET1
resolver
hgnc
HGNC:25477
resolver
uniprot
B3KNN6
resolver
uniprot
Q2VPC0
resolver
uniprot
Q9NWD5
resolver
uniprot_entry
DET1_HUMAN
resolver
uniprot_sec
B3KNN6
resolver
uniprot_sec
Q2VPC0
resolver
uniprot_sec
Q9NWD5
resolver
amino_acid_sequence
MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVNIRGRLFERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFFEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT
uniprot
proteins
function
FUNCTION: Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation. {ECO:0000269|PubMed:14739464}.
uniprot
proteins
mass_dalton
63848
uniprot
proteins
protein_family
DET1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14739464
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
550
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins