Ciao2a
entrez
68250
canonical
uniprot
Q9DCL2
canonical
ensembl
ENSMUSG00000032381
resolver
ensp
ENSMUSP00000034945
resolver
ensp
ENSMUSP00000297442
resolver
ensp
ENSMUSP00000297443
resolver
enst
ENSMUST00000034945
resolver
genesymbol
Ciao2a
resolver
genesymbol_syn
Fam96a
resolver
uniprot
Q3TD02
resolver
uniprot
Q9D171
resolver
uniprot_entry
CIA2A_MOUSE
resolver
uniprot_sec
Q3TD02
resolver
uniprot_sec
Q9D171
resolver
amino_acid_sequence
MERVSGLLSWTLSRVLWLSGFSEHGAAWQPRIMEEKALEVYDLIRTIRDPEKPNTLEELEVVTESCVEVQEINEDDYLVIIKFTPTVPHCSLATLIGLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVAAAMENPNLREIVEQCVLEPD
uniprot
proteins
function
FUNCTION: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2 (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). {ECO:0000250, ECO:0000269|PubMed:23891004, ECO:0000269|PubMed:25716227}.
uniprot
proteins
mass_dalton
18418
uniprot
proteins
protein_family
MIP18 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23891004
uniprot
proteins
pubmed
25716227
uniprot
proteins
pubmed
29320706
uniprot
proteins
sequence_length
160
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins