Gtpbp3
entrez
70359
canonical
uniprot
Q923K4
canonical
ensembl
ENSMUSG00000007610
resolver
ensp
ENSMUSP00000007754
resolver
ensp
ENSMUSP00000179781
resolver
genesymbol
Gtpbp3
resolver
uniprot
B2RRS4
resolver
uniprot
Q58E73
resolver
uniprot
Q99M99
resolver
uniprot_entry
B2RRS4_MOUSE
resolver
uniprot_entry
GTPB3_MOUSE
resolver
uniprot_sec
Q58E73
resolver
uniprot_sec
Q99M99
resolver
amino_acid_sequence
MWRGLSALVTQAAWAPLRLCARCSTSAESLVPSSTIFALSSGQGRCAIAVIRTSGPASGLALRSLTALQEPPPARRACLRLLRHPCSGEPLDRSLVLWFPGPQSFTGEDCVEFHVHGGPAVVSGVLQALGSVPGLRPAEAGEFTRRAFAHGKLSLTEVEGLADLIRAETEAQRRQALRQLDGELSQLCQGWAKTLTKALAYVEAYIDFGEDDNLEEGVLEQADREVRALEVALGSHLRDARRGQRLLSGANVVVTGPPNAGKSSLVNLLSQKPVSIVSPEPGTTRDVLETPVDLAGFPVLLSDTAGLREGVGAVEQEGVRRARHRLEQADIILGVLDASDLASSSSCSFLDTVVTPLLAQSQDSGGQRLLLLLNKSDLLSANAPACDIALPPHLLLSCHTGAGMDSLLQALKTELAAVCGDPSTGPPLLTRVRHQYHLQGCLDALGHYQLATDLALAAEALRQARRQLNHLTGGGGTEEILDLIFQDFCVGK
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
function
FUNCTION: GTPase component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity. {ECO:0000250|UniProtKB:Q969Y2}.
uniprot
proteins
mass_dalton
52175
uniprot
proteins
protein_family
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
uniprot
proteins
protein_family
TrmE GTPase family
uniprot
proteins
pubmed
14680828
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
492
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:14680828}.
uniprot
proteins