Slc67a1
entrez
18400
canonical
uniprot
Q78KK3
canonical
ensembl
ENSMUSG00000000154
resolver
ensp
ENSMUSP00000056082
resolver
ensp
ENSMUSP00000101537
resolver
ensp
ENSMUSP00000215607
resolver
ensp
ENSMUSP00000353583
resolver
enst
ENSMUST00000052348
resolver
enst
ENSMUST00000105917
resolver
genesymbol
Slc22a18
resolver
genesymbol
Slc67a1
resolver
genesymbol_syn
Impt1
resolver
genesymbol_syn
Itm
resolver
genesymbol_syn
Orctl2
resolver
genesymbol_syn
Slc22a18
resolver
genesymbol_syn
Tssc5
resolver
uniprot
A0A0R4J0P7
resolver
uniprot
O35428
resolver
uniprot
O54959
resolver
uniprot
O88283
resolver
uniprot
Q99NF4
resolver
uniprot_entry
A0A0R4J0P7_MOUSE
resolver
uniprot_entry
S67A1_MOUSE
resolver
uniprot_sec
O35428
resolver
uniprot_sec
O54959
resolver
uniprot_sec
O88283
resolver
uniprot_sec
Q99NF4
resolver
amino_acid_sequence
MAALPRQGIIILTYVLAALELTCLFMQFSILPYLSRTLGLDSVSFGYLQTTFGVLQLLGGPVFGRFADQCGARAALSLSFLAASALYLLLVASCSPALPGVFLLFASRIPSALMHTLPAAQMVITDLTAPTERPAALGRLGLCFGIGIIFGSLLGGTLNTAYGIQCPAILAFVVTLLGAVLSFTCVPATTKEASVQSAPQGGTKASVFDLKAITRLLLLPRVLPVFLVKVISGLPSGLFLVMFSIISMDFFQLEAAQAGYLMSFFGILQMMIQGLVIGRLSTHFPEEALLRSSVLVFAVVGLGMALMSSVLHFCFLMPGLVFSLCTLNVVTDSMLTKAVSASDTGTMLGLSASVQPLTRTLGPTLGGLLYRSYGVPIFGHVQLMVNLLVLLVLWKKPLSQKGEKAR
uniprot
proteins
function
FUNCTION: May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney (By similarity). Plays a role in the regulation of lipid metabolism (PubMed:38626531). {ECO:0000250|UniProtKB:Q96BI1, ECO:0000269|PubMed:38626531}.
uniprot
proteins
mass_dalton
43013
uniprot
proteins
protein_family
Major facilitator (TC 2.A.1) superfamily
uniprot
proteins
protein_family
Organic cation transporter (TC 2.A.1.19) family
uniprot
proteins
pubmed
11063728
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
38626531
uniprot
proteins
pubmed
9499412
uniprot
proteins
pubmed
9570947
uniprot
proteins
pubmed
9802569
uniprot
proteins
sequence_length
406
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:Q96BI1}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96BI1}. Note=Localized at the apical membrane surface of renal proximal tubules. {ECO:0000250|UniProtKB:Q96BI1}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 85..105; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 140..160; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 168..188; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 295..315; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 316..336; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 374..394; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins