Slc22a15
entrez
242126
canonical
uniprot
Q504N2
canonical
ensembl
ENSMUSG00000033147
resolver
ensp
ENSMUSP00000102541
resolver
genesymbol
Slc22a15
resolver
uniprot
A7MCW2
resolver
uniprot
F8WJ00
resolver
uniprot
Q8CDR3
resolver
uniprot_entry
S22AF_MOUSE
resolver
uniprot_sec
A7MCW2
resolver
uniprot_sec
F8WJ00
resolver
uniprot_sec
Q8CDR3
resolver
amino_acid_sequence
MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMADLLPNQSHSNQTLGKGQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIANRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFALDILFAVANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAVLVNLQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAKRNRKLKCTFSLTHPANRSYRATGSFLDLFRYRILLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPSLKEVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQMYSYRRLGEEALSLQTLDPPQPLDKVSSESEEEEEFYDADEETQMIK
uniprot
proteins
function
FUNCTION: Organic zwitterion/cation transporter with apparent specificity for amino acids and their derivatives. Substrate selectivity and the transport mechanism, symport with sodium or facilitated diffusion allosterically regulated by sodium, remain to be elucidated. {ECO:0000250|UniProtKB:Q8IZD6, ECO:0000269|PubMed:33124720}.
uniprot
proteins
mass_dalton
60286
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q8IZD6}.
uniprot
proteins
protein_family
Major facilitator (TC 2.A.1) superfamily
uniprot
proteins
protein_family
Organic cation transporter (TC 2.A.1.19) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
33124720
uniprot
proteins
sequence_length
544
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8IZD6}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 111..131; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 170..190; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 303..323; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 338..358; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 368..388; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 401..420; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 433..453; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 462..482; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins