Sgsm1
entrez
52850
canonical
uniprot
Q8BPQ7
canonical
ensembl
ENSMUSG00000042216
resolver
ensp
ENSMUSP00000046544
resolver
ensp
ENSMUSP00000084106
resolver
ensp
ENSMUSP00000107944
resolver
enst
ENSMUST00000048112
resolver
enst
ENSMUST00000112325
resolver
genesymbol
Sgsm1
resolver
genesymbol_syn
Rutbc2
resolver
uniprot
B2RQR5
resolver
uniprot
D3Z7V4
resolver
uniprot
F6RWY8
resolver
uniprot
Q3TJ12
resolver
uniprot_entry
B2RQR5_MOUSE
resolver
uniprot_entry
D3Z7V4_MOUSE
resolver
uniprot_entry
F6RWY8_MOUSE
resolver
uniprot_entry
SGSM1_MOUSE
resolver
uniprot_sec
Q3TJ12
resolver
amino_acid_sequence
MASVPAEAETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLHGLRRRAAGFLRSNKIAALFMKVGKGFPPAEELSRKVQELEQLIESARNQIQGLQENVRKLPKLPNLSPLAIKHLWIRTALFGRVLDKIVHYLVENSSKYYEKEALLMDPVDGPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHLRQDSPTKRPALCIQKRHSSGSMDDRPSISARDYVESLHQDSRATLLYGKNNVLVQPRDDMEAVPGYLSLHQTADVMTLKWTPNQLMNGSVGDLDYEKSVYWDYAVTIRLEEIVYLHCHQQVDSGGTVVLVSQDGIQRPPFRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVFPKLRKRSPQGSSESTSSDKEDDEATDYVFRIIYPGTQSEFVPQDLMDVSMNNLPPLWQPSPRKSSCSSCSQSGSADGGSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHMIVSPDLPCDAGQGLTASIWEKYIQDSTTYPEQELLRLIYYGGVQPEIRRAVWPFLLGHYQFGMTEMERKEVDEQIHACYAQTMSEWLGCEAIVRQRERESHAAALAKCSSGASLDSHLHRMLHRDSTISNESSQSCSSGRQNLRLQSDSSSSTQVFESVDEVEQTEAEGRSEEKHPKIPNGNPANGTCSPDSGHPSSHNFSSGLSEHSEPSLSTEDSVLDAQRSLPAVFRPGDSSVEDGQSSEATTSRDEAPREELAVQDSLESDLLANESLEEFMSIPGSLDVALPEKDGAVMDGWPGEADKPSRADSEDNLSEEPEMESLFPALASLAVTSSANNEASPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRSYWYFTAANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAERHNAKQILQLARDLVHKVQILIENK
uniprot
proteins
function
FUNCTION: Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as a GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B. {ECO:0000250|UniProtKB:Q2NKQ1}.
uniprot
proteins
mass_dalton
123196
uniprot
proteins
mutagenesis
MUTAGEN 256; /note="L->A: Abolishes interaction with RAB9A."; /evidence="ECO:0000269|PubMed:25220469"; MUTAGEN 260; /note="K->A: Abolishes interaction with RAB9A."; /evidence="ECO:0000269|PubMed:25220469"; MUTAGEN 261; /note="N->A: Abolishes interaction with RAB9A."; /evidence="ECO:0000269|PubMed:25220469"; MUTAGEN 262; /note="N->A: Mildly impaired interaction with RAB9A."; /evidence="ECO:0000269|PubMed:25220469"; MUTAGEN 277; /note="Y->A: Abolishes interaction with RAB9A."; /evidence="ECO:0000269|PubMed:25220469"; MUTAGEN 294; /note="N->A: Abolishes interaction with RAB9A."; /evidence="ECO:0000269|PubMed:25220469"; MUTAGEN 297; /note="M->A: Abolishes interaction with RAB9A."; /evidence="ECO:0000269|PubMed:25220469
uniprot
proteins
protein_family
RUTBC family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17509819
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25220469
uniprot
proteins
sequence_length
1093
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:17509819}. Cytoplasm {ECO:0000269|PubMed:25220469}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:25220469}; Peripheral membrane protein {ECO:0000269|PubMed:25220469}. Note=Recruited to cytoplasmic vesicle membranes via its interaction with Rab family members, such as RAB9A. {ECO:0000269|PubMed:25220469}.
uniprot
proteins