PFKFB3
entrez
5209
canonical
uniprot
Q16875
canonical
ensembl
ENSG00000170525
resolver
ensp
ENSP00000353712
resolver
ensp
ENSP00000369100
resolver
ensp
ENSP00000369115
resolver
ensp
ENSP00000443319
resolver
ensp
ENSP00000486311
resolver
ensp
ENSP00000492001
resolver
ensp
ENSP00000570175
resolver
enst
ENST00000640683
resolver
genesymbol
PFKFB3
resolver
hgnc
HGNC:8874
resolver
uniprot
A0A1W2PR17
resolver
uniprot
B7Z8A0
resolver
uniprot
B7Z955
resolver
uniprot
O43622
resolver
uniprot
O75902
resolver
uniprot
Q5VX15
resolver
uniprot
Q5VX18
resolver
uniprot
Q5VX19
resolver
uniprot_entry
A0A1W2PR17_HUMAN
resolver
uniprot_entry
B7Z8A0_HUMAN
resolver
uniprot_entry
F263_HUMAN
resolver
uniprot_sec
B7Z955
resolver
uniprot_sec
O43622
resolver
uniprot_sec
O75902
resolver
uniprot_sec
Q5VX15
resolver
uniprot_sec
Q5VX18
resolver
uniprot_sec
Q5VX19
resolver
amino_acid_sequence
MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
uniprot
proteins
ec_number
2.7.1.105
uniprot
proteins
ec_number
3.1.3.46
uniprot
proteins
function
FUNCTION: Catalyzes both the synthesis and degradation of fructose 2,6-bisphosphate. {ECO:0000269|PubMed:10077634, ECO:0000269|PubMed:17499765, ECO:0000305|PubMed:16316985}.
uniprot
proteins
mass_dalton
59609
uniprot
proteins
mutagenesis
MUTAGEN 45; /note="A->G: 20-fold decrease in Km for ATP and 3-fold decrease in Km for fructose-6 phsphate."; /evidence="ECO:0000269|PubMed:17499765"; MUTAGEN 169; /note="K->R,A,N: Loss of activity."; /evidence="ECO:0000269|PubMed:17499765
uniprot
proteins
post_translational_modification
PTM: Phosphorylation by AMPK stimulates activity. {ECO:0000269|PubMed:12065600}.
uniprot
proteins
protein_family
Phosphoglycerate mutase family
uniprot
proteins
pubmed
10072580
uniprot
proteins
pubmed
10077634
uniprot
proteins
pubmed
10508479
uniprot
proteins
pubmed
12065600
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16316985
uniprot
proteins
pubmed
17499765
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
22275052
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25849762
uniprot
proteins
pubmed
36402789
uniprot
proteins
pubmed
8830046
uniprot
proteins
pubmed
9146922
uniprot
proteins
sequence_length
520
uniprot
proteins