Fam168b
entrez
690188
canonical
uniprot
D4AEP3
canonical
ensembl
ENSRNOG00000023467
resolver
ensp
ENSRNOP00000033168
resolver
ensp
ENSRNOP00000112438
resolver
enst
ENSRNOT00000039480
resolver
genesymbol
Fam168b
resolver
uniprot
A0A8L2QHF9
resolver
uniprot_entry
A0A8L2QHF9_RAT
resolver
uniprot_entry
F168B_RAT
resolver
amino_acid_sequence
MNPVYSPGSSGVPYANAKGIGYPAGFPVGYAAAPAYSPNMYPGANPTFQTGYTPGTPYKVSCSPTSGAVPPYSSSPNPYQTAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPIPPPRGSGVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW
uniprot
proteins
function
FUNCTION: Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27. {ECO:0000269|PubMed:20716133}.
uniprot
proteins
mass_dalton
20194
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:20716133}.
uniprot
proteins
protein_family
FAM168 family
uniprot
proteins
pubmed
20716133
uniprot
proteins
pubmed
22771904
uniprot
proteins
sequence_length
194
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000269|PubMed:22771904}. Cell membrane {ECO:0000269|PubMed:22771904}; Multi-pass membrane protein {ECO:0000269|PubMed:22771904}. Cell projection, axon {ECO:0000269|PubMed:22771904}. Note=In cortical neurons, predominantly found at perinuclear regions. Expressed in neuronal cell bodies and axonal fibers. {ECO:0000269|PubMed:22771904}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..41; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 142..163; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins