Sdhd
entrez
66925
canonical
uniprot
Q9CXV1
canonical
ensembl
ENSMUSG00000000171
resolver
ensp
ENSMUSP00000000175
resolver
enst
ENSMUST00000000175
resolver
genesymbol
Sdhd
resolver
uniprot
A6H629
resolver
uniprot
Q3UX11
resolver
uniprot_entry
DHSD_MOUSE
resolver
uniprot_sec
A6H629
resolver
uniprot_sec
Q3UX11
resolver
amino_acid_sequence
MAVLLKLGVLCSGQGARALLLRSRVVRPAYVSAFLQDQPTQGRCGTQHIHLSPSHHSGSKAASLHWTSERVVSVLLLGLIPAGYLNPCSVVDYSLAAALTLHSHWGLGQVVTDYVHGDTLPKAARAGLLALSALTFAGLCYFNYHDVGICRAVAMLWKL
uniprot
proteins
function
FUNCTION: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). {ECO:0000250|UniProtKB:O14521, ECO:0000250|UniProtKB:Q95123}.
uniprot
proteins
mass_dalton
17014
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle. {ECO:0000250|UniProtKB:O14521}.
uniprot
proteins
protein_family
CybS family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
159
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:O14521}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 64..85; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O14521"; TRANSMEM 91..111; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O14521"; TRANSMEM 121..142; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O14521
uniprot
proteins