Ppp1r35
entrez
69871
canonical
uniprot
Q9D8C8
canonical
ensembl
ENSMUSG00000029725
resolver
ensp
ENSMUSP00000031739
resolver
enst
ENSMUST00000031739
resolver
genesymbol
Ppp1r35
resolver
uniprot_entry
PPR35_MOUSE
resolver
amino_acid_sequence
MMGFGASALESIEGEEALEVPGPPPEPRAPEPRAPEPEPGLDLSLSPSPLPESPKARKSSPGQRKGRRGGSRRGRQVRFQLAPPSPVRSEPLLVAGAPGDDHELEAPALQSSLALSLELQNARAAVASGQFDASKAVEEQLRKSFRTRCALEETVAEGLNVPRSKRLYRDLVSLQVPEEQVLNAALREKLAMLPPQPRAPPLKEVLGPGPDMTMLCNPDSLWSESPHLTVDGLPPLRLQARPRPSEDTFLMHRMLRRWEA
uniprot
proteins
function
FUNCTION: During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with TTTN, leading to the centriole to centrosome conversion (By similarity). In addition may play a role in the primary cilia assembly (PubMed:32628936). {ECO:0000250|UniProtKB:Q8TAP8, ECO:0000269|PubMed:32628936}.
uniprot
proteins
mass_dalton
28355
uniprot
proteins
protein_family
PPP1R35 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16926269
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
32628936
uniprot
proteins
sequence_length
260
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8TAP8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q8TAP8}. Note=Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel. Co-localizes with RTTN at the centriole. {ECO:0000250|UniProtKB:Q8TAP8}.
uniprot
proteins