MMP27
entrez
64066
canonical
uniprot
Q9H306
canonical
ensembl
ENSG00000137675
resolver
ensp
ENSP00000260229
resolver
enst
ENST00000260229
resolver
genesymbol
MMP27
resolver
hgnc
HGNC:14250
resolver
uniprot
Q6UWK6
resolver
uniprot_entry
MMP27_HUMAN
resolver
uniprot_sec
Q6UWK6
resolver
amino_acid_sequence
MKRLLLLFLFFITFSSAFPLVRMTENEENMQLAQAYLNQFYSLEIEGNHLVQSKNRSLIDDKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPDVGQYGYTLPGWRKYNLTYRIINYTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPLGVLGHAFPPGPGLGGDTHFDEDENWTKDGAGFNLFLVAAHEFGHALGLSHSNDQTALMFPNYVSLDPRKYPLSQDDINGIQSIYGGLPKEPAKPKEPTIPHACDPDLTFDAITTFRREVMFFKGRHLWRIYYDITDVEFELIASFWPSLPADLQAAYENPRDKILVFKDENFWMIRGYAVLPDYPKSIHTLGFPGRVKKIDAAVCDKTTRKTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPGISIRVDAAFQYKGFFFFSRGSKQFEYDIKTKNITRIMRTNTWFQCKEPKNSSFGFDINKEKAHSGGIKILYHKSLSLFIFGIVHLLKNTSIYQ
uniprot
proteins
ec_number
3.4.24.-
uniprot
proteins
function
FUNCTION: Matrix metalloproteinases degrade protein components of the extracellular matrix such as fibronectin, laminin, gelatins and/or collagens. {ECO:0000250}.
uniprot
proteins
mass_dalton
59026
uniprot
proteins
mutagenesis
MUTAGEN 55; /note="N->Q: Loss of N-glycosylation; when associated with Q-110 and Q-452."; /evidence="ECO:0000269|PubMed:24548619"; MUTAGEN 110; /note="N->Q: Loss of N-glycosylation; when associated with Q-55 and Q-452."; /evidence="ECO:0000269|PubMed:24548619"; MUTAGEN 452; /note="N->Q: Loss of N-glycosylation; when associated with Q-55 and Q-110."; /evidence="ECO:0000269|PubMed:24548619
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:24548619}.
uniprot
proteins
protein_family
Peptidase M10A family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14506071
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
24548619
uniprot
proteins
pubmed
24810263
uniprot
proteins
sequence_length
513
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:24548619}. Note=Retained in the endoplasmic reticulum due to a C-terminal extension (CTE). {ECO:0000269|PubMed:24548619}.
uniprot
proteins