Araf
entrez
11836
canonical
uniprot
P04627
canonical
ensembl
ENSMUSG00000001127
resolver
ensp
ENSMUSP00000001155
resolver
ensp
ENSMUSP00000112513
resolver
ensp
ENSMUSP00000112521
resolver
ensp
ENSMUSP00000162732
resolver
enst
ENSMUST00000001155
resolver
enst
ENSMUST00000120356
resolver
enst
ENSMUST00000122312
resolver
genesymbol
Araf
resolver
genesymbol_syn
A-raf
resolver
genesymbol_syn
Araf1
resolver
uniprot
B1AUN9
resolver
uniprot
F6SVG2
resolver
uniprot
Q8CAD1
resolver
uniprot
Q99J44
resolver
uniprot
Q9CTT5
resolver
uniprot
Q9D6R6
resolver
uniprot
Q9DBU7
resolver
uniprot_entry
ARAF_MOUSE
resolver
uniprot_entry
F6SVG2_MOUSE
resolver
uniprot_entry
Q8CAD1_MOUSE
resolver
uniprot_sec
B1AUN9
resolver
uniprot_sec
Q99J44
resolver
uniprot_sec
Q9CTT5
resolver
uniprot_sec
Q9D6R6
resolver
uniprot_sec
Q9DBU7
resolver
amino_acid_sequence
MEPPRGPPVSGAEPSRAVGTVKVYLPNKQRTVVTVREGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSIQDLSGGSRQQEAPSNLSVNELLTPQGPSPFTQQRDQEHFSFPAPANPPLQRIRSTSTPNVHMVSTTAPMDSSLMQFTAQSFSTDAAGRGGDGAPRGSPSPASVSSGRKSPHSKLPSEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade (By similarity). Phosphorylates PFKFB2 (By similarity). {ECO:0000250|UniProtKB:P10398}.
uniprot
proteins
mass_dalton
67581
uniprot
proteins
post_translational_modification
PTM: Dephosphorylation by the SHOC2-MRAS-PP1c (SMP) complex consisting of SHOC2, GTP-bound M-Ras/MRAS and the catalytic subunit of protein phosphatase 1 (PPP1CA, PPP1CB or PPP1CC); this relieves inactivation and stimulates kinase activity. {ECO:0000250|UniProtKB:P10398}.
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
RAF subfamily
uniprot
proteins
protein_family
TKL Ser/Thr protein kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
3491291
uniprot
proteins
sequence_length
604
uniprot
proteins