Dip2a
entrez
64451
canonical
uniprot
Q8BWT5
canonical
ensembl
ENSMUSG00000020231
resolver
ensp
ENSMUSP00000043710
resolver
ensp
ENSMUSP00000125184
resolver
ensp
ENSMUSP00000273739
resolver
ensp
ENSMUSP00000273741
resolver
enst
ENSMUST00000036033
resolver
enst
ENSMUST00000160048
resolver
genesymbol
Dip2a
resolver
genesymbol_syn
Dip2
resolver
genesymbol_syn
Kiaa0184
resolver
uniprot
E0CXM7
resolver
uniprot
F8WI56
resolver
uniprot
Q8CHI0
resolver
uniprot_entry
DIP2A_MOUSE
resolver
uniprot_entry
F8WI56_MOUSE
resolver
uniprot_sec
E0CXM7
resolver
uniprot_sec
Q8CHI0
resolver
amino_acid_sequence
MADRGCPLEAAPLPAEVLESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQDVHTEAVQAALAKYKERKMPMPSKRRSALVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTLLQSHSGIEPWLDRVIQGSSTSSSASSTSSHPGGRPAAAPSASTALAGLTAHAHIDLHSAPPDVTTGLVEHSSYERPQMASVRGIPRGHGRNVLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGDQMAVLKGEPLSVGTNGPLSLLAALQLWGTTQPKAPCLTALDTAGKATCTLTYGKLWSRSLKLAYTLLNKLTSKNEPLLNPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRKDAGSQQVGFLLGSCGVTLALTTDACQKGLPKAPTGEVATFKGWPPLAWLVIDGKHLTRPPKDWYPLAQDTGSRTAYIEYKTSKEGSTVGVTVSHSSLLAQCQALTQACGYTEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVITIPYALMKVNPLSWIQKVCSYKARAALVKSRDMHWSLLAQRGQRDVCLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGASVCVVKVDGAPYLCKTDEIGEICVNSVATGTAYYGLLGITKNTFETVPVTADGVPVSDRPFTRTGLLGFIGPDNLVFVVGKLDGLMVVGVRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPASMIVGNLVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKGTVTSTATCIQLHKRAERVAAALMEKGRLDAGDHVALVYPPGVDLIAAFYGCLYCGCVPVTVRPPHPQNLGTTLPTVKMIVEVSKSACVLSTQAITRLLKSKEAAAAVDVRTWPTILDTDDIPKKKVASIFRPPSPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVMEMCTKGLGAQTGALRMKGVNLSCVRTCMVVAEERPRISLTQSFSKLFKDLGLPARAVSTTFGCRVNVAICLQGTTGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYGEETLHADHFSARLSFGDTQTIWARTGYLGFLRRTELTDASGERHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNLLVVVVELDGLEQDALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
uniprot
proteins
ec_number
6.2.1.1
uniprot
proteins
function
FUNCTION: Catalyzes the de novo synthesis of acetyl-CoA in vitro (PubMed:30672040). Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (PubMed:31600191). Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes (By similarity). {ECO:0000250|UniProtKB:Q14689, ECO:0000269|PubMed:30672040, ECO:0000269|PubMed:31600191}.
uniprot
proteins
mass_dalton
165255
uniprot
proteins
mutagenesis
MUTAGEN 235..238; /note="PKRP->AKRA: Significantly reduced interaction with CTTN; when associated with 259-ANQA-262."; /evidence="ECO:0000269|PubMed:31600191"; MUTAGEN 259..262; /note="PNQP->ANQA: Significantly reduced interaction with CTTN; when associated with 235-AKRA-238."; /evidence="ECO:0000269|PubMed:31600191
uniprot
proteins
protein_family
DIP2 family
uniprot
proteins
pubmed
12137943
uniprot
proteins
pubmed
12465718
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20054002
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26605542
uniprot
proteins
pubmed
30672040
uniprot
proteins
pubmed
31600191
uniprot
proteins
sequence_length
1523
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q14689}; Peripheral membrane protein {ECO:0000305}. Mitochondrion {ECO:0000269|PubMed:30672040}. Cell projection, dendritic spine {ECO:0000269|PubMed:31600191}.
uniprot
proteins