CISD3
entrez
284106
canonical
uniprot
P0C7P0
canonical
ensembl
ENSG00000274768
resolver
ensembl
ENSG00000277972
resolver
ensp
ENSP00000483781
resolver
ensp
ENSP00000484950
resolver
enst
ENST00000613478
resolver
enst
ENST00000620783
resolver
genesymbol
CISD3
resolver
hgnc
HGNC:27578
resolver
uniprot_entry
CISD3_HUMAN
resolver
amino_acid_sequence
MRGAGAILRPAARGARDLNPRRDISSWLAQWFPRTPARSVVALKTPIKVELVAGKTYRWCVCGRSKKQPFCDGSHFFQRTGLSPLKFKAQETRMVALCTCKATQRPPYCDGTHRSERVQKAEVGSPL
uniprot
proteins
function
FUNCTION: Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function. {ECO:0000269|PubMed:29259115}.
uniprot
proteins
mass_dalton
14216
uniprot
proteins
mutagenesis
MUTAGEN 75; /note="H->C: Increases iron-sulfur cluster stability; when associated with C-113."; /evidence="ECO:0000269|PubMed:29259115"; MUTAGEN 113; /note="H->C: Increases iron-sulfur cluster stability; when associated with C-75."; /evidence="ECO:0000269|PubMed:29259115
uniprot
proteins
protein_family
CISD protein family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
17376863
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
29259115
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:17376863}.
uniprot
proteins