MMRN2
entrez
79812
canonical
uniprot
Q9H8L6
canonical
ensembl
ENSG00000173269
resolver
ensp
ENSP00000361097
resolver
ensp
ENSP00000566246
resolver
enst
ENST00000372027
resolver
enst
ENST00000896187
resolver
genesymbol
MMRN2
resolver
genesymbol_syn
EMILIN3
resolver
hgnc
HGNC:19888
resolver
uniprot
Q504V7
resolver
uniprot
Q6P2N2
resolver
uniprot_entry
MMRN2_HUMAN
resolver
uniprot_sec
Q504V7
resolver
uniprot_sec
Q6P2N2
resolver
amino_acid_sequence
MILSLLFSLGGPLGWGLLGAWAQASSTSLSDLQSSRTPGVWKAEAEDTGKDPVGRNWCPYPMSKLVTLLALCKTEKFLIHSQQPCPQGAPDCQKVKVMYRMAHKPVYQVKQKVLTSLAWRCCPGYTGPNCEHHDSMAIPEPADPGDSHQEPQDGPVSFKPGHLAAVINEVEVQQEQQEHLLGDLQNDVHRVADSLPGLWKALPGNLTAAVMEANQTGHEFPDRSLEQVLLPHVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKRLHKAQEAPGTNGSLVLATPGAGARPEPDSLQARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAVSLAVDAHKAEGERARAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAALFGEEVLEEMSEQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELAARVTALEQASEPPRPAEHLEPSHDAGREEAATTALAGLARELQSLSNDVKNVGRCCEAEAGAGAASLNASLHGLHNALFATQRSLEQHQRLFHSLFGNFQGLMEANVSLDLGKLQTMLSRKGKKQQKDLEAPRKRDKKEAEPLVDIRVTGPVPGALGAALWEAGSPVAFYASFSEGTAALQTVKFNTTYINIGSSYFPEHGYFRAPERGVYLFAVSVEFGPGPGTGQLVFGGHHRTPVCTTGQGSGSTATVFAMAELQKGERVWFELTQGSITKRSLSGTAFGGFLMFKT
uniprot
proteins
function
FUNCTION: Extracellular matrix protein (PubMed:22020326, PubMed:28671670, PubMed:28912033). Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation (PubMed:22020326, PubMed:28671670, PubMed:28912033). Positively regulates angiogenesis by acting as a ligand for CD93 receptor (PubMed:28671670, PubMed:28912033). {ECO:0000269|PubMed:22020326, ECO:0000269|PubMed:28671670, ECO:0000269|PubMed:28912033}.
uniprot
proteins
mass_dalton
104409
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000269|PubMed:16335952}.; PTM: O-fucosylated within the EMI domain (at Ser-63, Thr-67 and Thr-115) by POFUT3 and POFUT4. {ECO:0000269|PubMed:39775168}.
uniprot
proteins
pubmed
11559704
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
22020326
uniprot
proteins
pubmed
28435016
uniprot
proteins
pubmed
28671670
uniprot
proteins
pubmed
28912033
uniprot
proteins
pubmed
39775168
uniprot
proteins
pubmed
41107108
uniprot
proteins
sequence_length
949
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:11559704}.
uniprot
proteins