HRH3
entrez
11255
canonical
uniprot
Q9Y5N1
canonical
ensembl
ENSG00000101180
resolver
ensp
ENSP00000321482
resolver
ensp
ENSP00000342560
resolver
genesymbol
HRH3
resolver
genesymbol_syn
GPCR97
resolver
hgnc
HGNC:5184
resolver
uniprot
Q4QRI7
resolver
uniprot
Q9GZX2
resolver
uniprot
Q9H4K8
resolver
uniprot_entry
HRH3_HUMAN
resolver
uniprot_sec
Q4QRI7
resolver
uniprot_sec
Q9GZX2
resolver
uniprot_sec
Q9H4K8
resolver
amino_acid_sequence
MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK
uniprot
proteins
function
FUNCTION: The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
uniprot
proteins
mass_dalton
48671
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10347254
uniprot
proteins
pubmed
11118334
uniprot
proteins
pubmed
11284713
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
11956964
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
445
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 71..91; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 109..129; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 157..177; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 197..217; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 360..380; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 396..416; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins