Aktip
entrez
291906
canonical
uniprot
Q5FVH4
canonical
ensembl
ENSRNOG00000011956
resolver
ensp
ENSRNOP00000082936
resolver
ensp
ENSRNOP00000091269
resolver
ensp
ENSRNOP00000092612
resolver
ensp
ENSRNOP00000105243
resolver
enst
ENSRNOT00000108713
resolver
enst
ENSRNOT00000109943
resolver
enst
ENSRNOT00000113279
resolver
enst
ENSRNOT00000143979
resolver
genesymbol
Aktip
resolver
genesymbol_syn
Fts
resolver
uniprot
A0A8I6AI00
resolver
uniprot
A0A8I6AQ33
resolver
uniprot
A0A8I6GA43
resolver
uniprot_entry
A0A8I6AI00_RAT
resolver
uniprot_entry
A0A8I6AQ33_RAT
resolver
uniprot_entry
A0A8I6GA43_RAT
resolver
uniprot_entry
AKTIP_RAT
resolver
amino_acid_sequence
MNPLWSMSSGSVRKRAEGEEKTLAGDVKTSPPRSAPKKQLPSIPKNALPISKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTMVVKQKLPGVYVQPSYRSALVWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDPTSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTTSPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKPDEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT
uniprot
proteins
function
FUNCTION: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell. {ECO:0000250|UniProtKB:Q9H8T0}.
uniprot
proteins
mass_dalton
32992
uniprot
proteins
protein_family
FTS subfamily
uniprot
proteins
protein_family
Ubiquitin-conjugating enzyme family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
292
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H8T0}. Cell membrane {ECO:0000250|UniProtKB:Q9H8T0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9H8T0}.
uniprot
proteins