MED21
entrez
9412
canonical
uniprot
Q13503
canonical
ensembl
ENSG00000152944
resolver
ensp
ENSP00000282892
resolver
ensp
ENSP00000674450
resolver
enst
ENST00000282892
resolver
genesymbol
MED21
resolver
genesymbol_syn
SRB7
resolver
genesymbol_syn
SURB7
resolver
hgnc
HGNC:11473
resolver
uniprot
A0A024RAW0
resolver
uniprot
B2R4I3
resolver
uniprot
Q6IB05
resolver
uniprot
Q92811
resolver
uniprot_entry
A0A024RAW0_HUMAN
resolver
uniprot_entry
MED21_HUMAN
resolver
uniprot_sec
B2R4I3
resolver
uniprot_sec
Q6IB05
resolver
uniprot_sec
Q92811
resolver
amino_acid_sequence
MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFNNIQTAINKDQPANPTEEYAQLFAALIARTAKDIDVLIDSLPSEESTAALQAASLYKLEEENHEAATCLEDVVYRGDMLLEKIQSALADIAQSQLKTRSGTHSQSLPDS
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:15249124, ECO:0000269|PubMed:9660976}.
uniprot
proteins
mass_dalton
15564
uniprot
proteins
protein_family
Mediator complex subunit 21 family
uniprot
proteins
pubmed
10024883
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15175163
uniprot
proteins
pubmed
15249124
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15989967
uniprot
proteins
pubmed
8598913
uniprot
proteins
pubmed
8609996
uniprot
proteins
pubmed
9660976
uniprot
proteins
pubmed
9734358
uniprot
proteins
pubmed
9933582
uniprot
proteins
sequence_length
144
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins