Grik5
entrez
24407
canonical
uniprot
Q63273
canonical
ensembl
ENSRNOG00000020310
resolver
ensp
ENSRNOP00000027578
resolver
enst
ENSRNOT00000027578
resolver
genesymbol
Grik5
resolver
uniprot
A0A8L2QF05
resolver
uniprot
Q62643
resolver
uniprot_entry
A0A8L2QF05_RAT
resolver
uniprot_entry
GRIK5_RAT
resolver
uniprot_sec
Q62643
resolver
amino_acid_sequence
MPAELLLLLIVAFANPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLVLRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWWEGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLYSAGAGGDAGAHGGPQRLLDDPGPPGGPRPQAPTPCTHVRVCQECRRIQALRASGAGAPPRGLGTPAEATSPPRPRPGPTGPRELTEHE
uniprot
proteins
function
FUNCTION: Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Cannot form functional channels on its own and produces channel activity only in heteromeric assembly with GRIK1, GRIK2 and GRIK3 subunits. {ECO:0000269|PubMed:1373632, ECO:0000269|PubMed:25139762, ECO:0000269|PubMed:9254673, ECO:0000269|PubMed:9390526}.
uniprot
proteins
mass_dalton
109276
uniprot
proteins
protein_family
GRIK5 subfamily
uniprot
proteins
protein_family
Glutamate-gated ion channel (TC 1.A.10.1) family
uniprot
proteins
pubmed
12954862
uniprot
proteins
pubmed
1373632
uniprot
proteins
pubmed
20951142
uniprot
proteins
pubmed
21791290
uniprot
proteins
pubmed
22509486
uniprot
proteins
pubmed
25139762
uniprot
proteins
pubmed
9254673
uniprot
proteins
pubmed
9390526
uniprot
proteins
sequence_length
979
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:1373632, ECO:0000269|PubMed:22509486}; Multi-pass membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000269|PubMed:12954862}; Multi-pass membrane protein {ECO:0000255}. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q61626}; Multi-pass membrane protein {ECO:0000255}. Note=Association with GRIK2 is required for its cell membrane localization. {ECO:0000269|PubMed:22509486}.
uniprot
proteins
transmembrane_region
TRANSMEM 545..565; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 623..643; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 804..824; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins