Ash1l
entrez
192195
canonical
uniprot
Q99MY8
canonical
ensembl
ENSMUSG00000028053
resolver
ensp
ENSMUSP00000088451
resolver
ensp
ENSMUSP00000140251
resolver
enst
ENSMUST00000090933
resolver
enst
ENSMUST00000186583
resolver
genesymbol
Ash1l
resolver
uniprot
E9QNM2
resolver
uniprot
Q3U598
resolver
uniprot
Q80VY5
resolver
uniprot
Q8BM69
resolver
uniprot
Q8BTX0
resolver
uniprot
Q8BZY6
resolver
uniprot_entry
ASH1L_MOUSE
resolver
uniprot_sec
E9QNM2
resolver
uniprot_sec
Q3U598
resolver
uniprot_sec
Q80VY5
resolver
uniprot_sec
Q8BM69
resolver
uniprot_sec
Q8BTX0
resolver
uniprot_sec
Q8BZY6
resolver
amino_acid_sequence
MDPRNTAMLGLGSDSEGFSRKSPSTINPGTLASKREAEIEGATEEEDPRKRNRERGTEAGKEDGSTDAQQQFSVKETNFSEGNLKLKIGLQAKRTKKPPKNLENYVCRPAIKTTIKHSRKALKSGKMTDEKNEHCPSKWDSSKLFKKAGDATAIDCQAEESIHLHSQGESNPLSKKLSPVHSQMADYISAAPSLVGSRDPDIKDRALLNGGTSVTEKLAQLIATCPPSKSSKAKPKKLGTGTTVGLVSKDLIRKPGVGSIAGIIHKDLIKKPALSTAVGLVTKDPGKKPMFNAAVGLINKDSVKKLGTGTTAVFINKDLGKKPGAITTVGLLSKESGKKLGIGIVPGLVNKESGKKLGLGTVVGLVNKELGKKLSSTVGLVAKDVTKKIVASSAMGLVNKDIGKKLLNCPMAGQLGSKDALNLKSEALLPTQEQLKASCSANISNHDSQELPESLKDSATGKAFEKSVMRHSKESMLEKFSVRKEITNLEKEMFNEGTCIQQDNFSSSERGAFETSKHEKQPPVYCTSPDFQIGGASDASTAKSPFSAVGESNLPSSSPTVSVNPVTRSPPEASSQLVPNPLLLNSTAEQMEEISESIGKSQFTAESTHLNVGHRSLGHSLSIECKGIDKELNESKNTHLDIPRISSSLGKKPSLTSDSGIHAITPSVVNFTSLFSNKPFLKLGAVTAPDKHCQVAESLSSSFQSKPLKKRKGRKPRWTKVVARSTCRSPKGLDLERSELFKNVSCSSLSNSSEPAKFMKTIGASSFVDHDFLKRRLPKLSKSSAPSLALLTDSEKPSHKSFITHKLSSSMCVTSDLLSDIYKPKRGRPKSKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQSLSVSPFPKKRGRPKRQMRSPVKMKPPVLSVAPFVATESPSKLESESENHRSSSDFFESEDQLQDTDDLDDSHRQSVCSMSDLEMEPDKKISKRNNGQLMKTIIRKINKMKTLKRKKLLNQILSSSVESSNKGKVQSKLHNTVSSLAATFGSKLGQQINVSKKGTIYIGKRRGRKPKTVLNGLLSGSPASLAVLEQTAQQAAGSALGQILPPLLPSPASSSEILPSPICSQSSGTSGGQSPVSSDAGFVEPSSVPYLHVHSRQGSMIQTLAMKKASKGRRRLSPPTLLPNSPSHLSELTSLKEATPSPVSESHSDETIPSDSGIGTDNNSTSDRAEKFCGQKKRRHSFEHISLIPPETSTVLNSLKEKHKHKCKRRSHDYLSYDKMKRQKRKRKKKYPQLRNRQDPDFIAELEELISRLSEIRITHRSHHFIPRDLLPTIFRINFNSFYTHPSFPLDPLHYIRKPDLKKKRGRPPKMREAMAEMPFMHSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLLLNPTKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHKHREHRSEQPQVSMDSGSSRSVLESLKRYRFGKDTVGDRYKHKEKHRCHMSCPHLSPSKNLINREEQWVSREPSESSSLALGLQTPLQIDCSESSPSLSLGGFTPNSEPASSDEHMNLFTSAIGSCRVSNPNSSCRKKLTDSPGLFPVQDTALNRPHRKEPLPSSERAIQSLAGSQSASDKPSQRSSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASMDDSVDSLLQRIVHHDEQESMEKNGDASITTVSAPPSSSPGHSYSKERALGKSDSLLVPAVPNDSCSNIPLLSEKSASRCSPHHIKRSVVEAMQRQARKMCNYDKILATKKNLDHVNKILKAKKLQRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQFVSPELNEGEDMSLHLSPDTVTDVIEAVVQSVNLTSEHKKGVKRKNWLLEEQTRKKQKTVPEEEEQENNKSFIETPVEIPSPLETPAEPSEPENTLQPVLALIPREKKAPRPPKKKYQRAGLYSDVYKTIDPKSRLIQLKKEKLEYTPGEHEYGLFPAPIHVGKYLRQKRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCGDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRMNGLPSHKGSQSSSTHRKSARAKEKRKSKHKLKKRKGHPSEEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIHQKQEEVKHTRDIHSASLYTRWNGLCRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENLEVARAARLAQIFKEICDGIISYRDSSQQTLAAPLLNLPPKKKNADYYEKISDPLDLSTIEKQILIGYYKTVEAFDADMLKVFRNAEKYYGRKSPIGRDVCRLRKAYYSARHEASAQIDEIVGETASEADSSETSVSEKESGHEKDDDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNTDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGIKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKRDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQEQAAREVPSPEEPDQERATGDIGDAEKKPEESSQEAQLASTPEERRHSQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFIPENSFRK
uniprot
proteins
ec_number
2.1.1.359
uniprot
proteins
ec_number
2.1.1.367
uniprot
proteins
function
FUNCTION: Histone methyltransferase specifically trimethylating 'Lys-36' of histone H3 forming H3K36me3 (By similarity). Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (PubMed:22939622). The physiological significance of the H3K9me1 activity is unclear (Probable) (PubMed:22939622). {ECO:0000250|UniProtKB:Q9NR48, ECO:0000269|PubMed:22939622, ECO:0000305|PubMed:22939622}.
uniprot
proteins
mass_dalton
331333
uniprot
proteins
post_translational_modification
PTM: Methylated at Gln-1218 by N6AMT1. {ECO:0000250|UniProtKB:Q9NR48}.
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
Histone-lysine methyltransferase family
uniprot
proteins
protein_family
SET2 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22939622
uniprot
proteins
pubmed
23576753
uniprot
proteins
sequence_length
2958
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NR48}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q9NR48}. Chromosome {ECO:0000250|UniProtKB:Q9NR48}. Note=The relevance of tight junction localization is however unclear. {ECO:0000250|UniProtKB:Q9NR48}.
uniprot
proteins