Pinx1
entrez
305963
canonical
uniprot
A4L691
canonical
ensembl
ENSRNOG00000012012
resolver
ensembl
ENSRNOG00055006596
resolver
ensembl
ENSRNOG00060020615
resolver
ensembl
ENSRNOG00065030745
resolver
ensp
ENSRNOP00000016027
resolver
ensp
ENSRNOP00000085367
resolver
ensp
ENSRNOP00055008310
resolver
ensp
ENSRNOP00060029387
resolver
ensp
ENSRNOP00065043516
resolver
enst
ENSRNOT00000016027
resolver
enst
ENSRNOT00000102140
resolver
enst
ENSRNOT00055010725
resolver
enst
ENSRNOT00060035725
resolver
enst
ENSRNOT00065052989
resolver
genesymbol
Pinx1
resolver
uniprot
A0A8I6A1H3
resolver
uniprot
B0BMT3
resolver
uniprot_entry
A0A8I6A1H3_RAT
resolver
uniprot_entry
B0BMT3_RAT
resolver
uniprot_entry
PINX1_RAT
resolver
amino_acid_sequence
MSMLAERRRKQKWAVDPRNTAWSNDDSKFGQKMLEKMGWSKGKGLGAQEQGATEHIKVKVKNNHLGLGATNNNEDNWIAHQDDFNQLLAALNTCHGQETADSSDNKEKKSFSLEEKSKISKNRVHYMKFTKGKDLSSRSETDLDCIFGKRRNKKLAQDGCSNSTADEADTSLTTTTTTTSAFTIQEYFAKRMAQLKSKSQAAAPGSDLSETPIEWKKGKKKTKEAAGTDIENSPQHKAKRHKKKKRVEAERGPAAKKRDQVELQPGGPSGDECSDASVEAAEDRVQTPDTQDDVPKPRKRRAKKTLQRPGGVAVDTAPDSAPVKKKKKVSR
uniprot
proteins
function
FUNCTION: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity). {ECO:0000250, ECO:0000269|PubMed:17624691}.
uniprot
proteins
mass_dalton
36710
uniprot
proteins
protein_family
PINX1 family
uniprot
proteins
pubmed
17624691
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q96BK5}. Nucleus, nucleolus {ECO:0000269|PubMed:17624691}. Chromosome, telomere {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE (By similarity). {ECO:0000250}.
uniprot
proteins