RASA3
entrez
22821
canonical
uniprot
Q14644
canonical
ensembl
ENSG00000185989
resolver
ensembl
ENSG00000280477
resolver
ensp
ENSP00000335029
resolver
ensp
ENSP00000689742
resolver
genesymbol
RASA3
resolver
hgnc
HGNC:20331
resolver
uniprot
A6NL15
resolver
uniprot
F8W6X8
resolver
uniprot
Q8IUY2
resolver
uniprot_entry
RASA3_HUMAN
resolver
uniprot_sec
A6NL15
resolver
uniprot_sec
F8W6X8
resolver
uniprot_sec
Q8IUY2
resolver
amino_acid_sequence
MAVEDEGLRVFQSVKIKIGEAKNLPSYPGPSKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRIVECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKRKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI
uniprot
proteins
function
FUNCTION: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.
uniprot
proteins
mass_dalton
95699
uniprot
proteins
mutagenesis
MUTAGEN 599; /note="K->Q: No binding to IP4 and loss of plasma membrane localization."; /evidence="ECO:0000269|PubMed:9382842"; MUTAGEN 600; /note="K->Q: No binding to IP4 and loss of plasma membrane localization."; /evidence="ECO:0000269|PubMed:9382842"; MUTAGEN 601; /note="R->Q: No binding to IP4 and loss of plasma membrane localization."; /evidence="ECO:0000269|PubMed:9382842
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18088087
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25489052
uniprot
proteins
pubmed
7637787
uniprot
proteins
pubmed
9382842
uniprot
proteins
sequence_length
834
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane.
uniprot
proteins