Mvd
entrez
81726
canonical
uniprot
Q62967
canonical
ensembl
ENSRNOG00000013376
resolver
ensp
ENSRNOP00000080265
resolver
genesymbol
Mvd
resolver
genesymbol_syn
Mpd
resolver
uniprot
Q642E5
resolver
uniprot_entry
MVD1_RAT
resolver
uniprot_sec
Q642E5
resolver
amino_acid_sequence
MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTAAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTGDGDALPLSLGYKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRVLILVVSAEKKPTGSTVGMQTSVATSTLLKFRAESIVPERMKEMTRCIQEQDFQAFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNAHHGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKTSLATEPSPGGVQYIIATQVGPGPQVLDDPHHHLLGPDGLPQRDL
uniprot
proteins
ec_number
4.1.1.33
uniprot
proteins
function
FUNCTION: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. {ECO:0000250|UniProtKB:P53602}.
uniprot
proteins
mass_dalton
43893
uniprot
proteins
pathway_participation
PATHWAY: Steroid biosynthesis; cholesterol biosynthesis. {ECO:0000305}.
uniprot
proteins
protein_family
Diphosphomevalonate decarboxylase family
uniprot
proteins
pubmed
11725955
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
401
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11725955}.
uniprot
proteins