Sub1
entrez
20024
canonical
uniprot
P11031
canonical
ensembl
ENSMUSG00000022205
resolver
ensp
ENSMUSP00000022816
resolver
ensp
ENSMUSP00000106130
resolver
ensp
ENSMUSP00000238197
resolver
enst
ENSMUST00000022816
resolver
enst
ENSMUST00000110504
resolver
genesymbol
Sub1
resolver
genesymbol_syn
Pc4
resolver
genesymbol_syn
Rpo2tc1
resolver
uniprot
Q3UJR5
resolver
uniprot
Q543N2
resolver
uniprot_entry
TCP4_MOUSE
resolver
uniprot_sec
Q3UJR5
resolver
uniprot_sec
Q543N2
resolver
amino_acid_sequence
MPKSKELVSSSSSGSDSDSEVEKKLKRKKQAVPEKPVKKQKPGETSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL
uniprot
proteins
function
FUNCTION: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
uniprot
proteins
mass_dalton
14427
uniprot
proteins
post_translational_modification
PTM: Activity is controlled by protein kinases that target the regulatory region. Phosphorylation inactivates both ds DNA-binding and cofactor function, but does not affect binding to ssDNA (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Transcriptional coactivator PC4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
3372536
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins