Rrn3
entrez
106298
canonical
uniprot
B2RS91
canonical
ensembl
ENSMUSG00000022682
resolver
ensp
ENSMUSP00000023363
resolver
enst
ENSMUST00000023363
resolver
genesymbol
Rrn3
resolver
uniprot
Q7TNE7
resolver
uniprot
Q8K052
resolver
uniprot_entry
RRN3_MOUSE
resolver
uniprot_sec
Q7TNE7
resolver
uniprot_sec
Q8K052
resolver
amino_acid_sequence
MAAPLLHTRLSGDVTAAASATLSASRTGLSDMLALESDFFNSPPKKTVRFGGTVTEVLLKYKKGETNDLELLKNQLSDPDIKDDQIINWLLEFRSSVMYLTKDFEQLINIILRLPWLNRSQRVVEEYLAFLGNLVSAQTVFLRPCLSMIASHFVPPRVIVKEGGIDVSDSDDEDDNLPAIFDTCHRALQIITRYVPSTPWFLMPILVEKFPFVRKSERTLECYVHNLLRISLYFPTLRREILELVIEKLLKLDVSVSRQDIEDAEEKAAQTCGGTDTTEGLFNMDEDEDTDPEKKADQEQPNQMAHPTAERLDVLLCLLLSYIEDVCRVHGKIDNNKTKDLYRDLISIFDKLLLPTHASCHVQFFMFFLCSFKLGFAEAFLEHLWKKLQDPNNPAIIRQAAANYIGSFLARAKFIPLITVKTCLDLLVNWLHMYLTNQDSGTKAFCDVALHGPFYSACQAVFYTVVFRHKQLLSGNLKQGLQYLQSLNFERIVLSQLNPLKICLPQVVNFFAAITNKYQLVFCYTIMERNSRQMLPVIRSTAGGDSVQTCTNPLDTFFPFDPCVLKRSKKFIDPIYQIWEDGSAEELQEFKKSTKKEVVEDEDDDFLKGEVPQSDTVTGLTPSSFDTHFQSPSSSVGSPPVLYIPGQSPLLTRIYD
uniprot
proteins
function
FUNCTION: Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent pre-initiation complex (PIC). {ECO:0000269|PubMed:12015311, ECO:0000269|PubMed:12646563}.
uniprot
proteins
mass_dalton
74518
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at Thr-198 by MAPK9/JNK2, which abrogates initiation complex formation. {ECO:0000250}.
uniprot
proteins
protein_family
RRN3 family
uniprot
proteins
pubmed
12015311
uniprot
proteins
pubmed
12646563
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
656
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:12015311}.
uniprot
proteins