Cndp2
entrez
291394
canonical
uniprot
Q6Q0N1
canonical
ensembl
ENSRNOG00000015591
resolver
ensembl
ENSRNOG00055013564
resolver
ensembl
ENSRNOG00060014955
resolver
ensembl
ENSRNOG00065002815
resolver
ensp
ENSRNOP00000021400
resolver
ensp
ENSRNOP00055018884
resolver
ensp
ENSRNOP00060020434
resolver
ensp
ENSRNOP00065002730
resolver
enst
ENSRNOT00000021400
resolver
enst
ENSRNOT00055023264
resolver
enst
ENSRNOT00060025607
resolver
enst
ENSRNOT00065003871
resolver
genesymbol
Cndp2
resolver
uniprot_entry
CNDP2_RAT
resolver
amino_acid_sequence
MSALKAVFQYIDENQDRFVKKLAEWVAIQSVSAWPEKRGEIRRMTEAAAADVQRLGGSVELVDIGKQKLPDGSEIPLPPILLGKLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVEREGKLYGRGSTDDKGPVAGWMNALEAYQKTGQEIPVNLRFCLEGMEESGSEGLDELIFAQKDKFFKDVDYVCISDNYWLGKNKPCITYGLRGICYFFIEVECSDKDLHSGVYGGSVHEAMTDLISLMGCLIDKKGKILIPGINDAVAPVTDEEHELYDHIDFDMEEFAKDVGAGTLLHSCKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPDMIPEVVSEQVSSYLSKKFAELQSPNKFKVYMGHGGKPWVSDFNHPHYQAGRRALKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRLNYIEGTKMLAAYLYEVSQLKN
uniprot
proteins
ec_number
3.4.-.-
uniprot
proteins
ec_number
3.4.13.18
uniprot
proteins
function
FUNCTION: Cytosolic metallodipeptidase with broad substrate specificity that catalyzes the hydrolysis of amide bonds in dipeptides and pseudopeptides. Substrates include L-cysteinylglycine, an intermediate metabolite of the gamma-glutamyl cycle of glutathione metabolism (By similarity). Can also hydrolyze threonyl-containing dipeptides (By similarity). Upon physiological conditions of amino acids and lactate excess can also catalyze a reverse proteolysis reaction, generating N-[(S)-lactoyl]-L-phenylalanine and possibly other N-lactoyl-amino acids which it can also hydrolyze in vitro. N-[(S)-lactoyl]-L-phenylalanine is an exercise-induced metabolite that influences food intake and systemic energy balance. Carnosine is probably not a physiological substrate and L-homocarnosine is not a substrate for this enzyme. Plays a role in the regulation of cell cycle arrest and apoptosis (By similarity). {ECO:0000250|UniProtKB:Q96KP4, ECO:0000250|UniProtKB:Q9D1A2}.
uniprot
proteins
mass_dalton
52693
uniprot
proteins
protein_family
Peptidase M20A family
uniprot
proteins
pubmed
15326124
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18790006
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
475
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q96KP4}.
uniprot
proteins