PWWP3A
entrez
84939
canonical
uniprot
Q2TAK8
canonical
ensembl
ENSG00000160953
resolver
ensp
ENSP00000465838
resolver
ensp
ENSP00000467287
resolver
ensp
ENSP00000468322
resolver
ensp
ENSP00000468557
resolver
ensp
ENSP00000498656
resolver
ensp
ENSP00000523307
resolver
ensp
ENSP00000583208
resolver
ensp
ENSP00000650179
resolver
ensp
ENSP00000753996
resolver
ensp
ENSP00000797418
resolver
enst
ENST00000587460
resolver
enst
ENST00000588810
resolver
enst
ENST00000591433
resolver
enst
ENST00000652273
resolver
genesymbol
PWWP3A
resolver
genesymbol_syn
EXPAND1
resolver
genesymbol_syn
MUM1
resolver
hgnc
HGNC:29641
resolver
uniprot
A1L489
resolver
uniprot
B5ME02
resolver
uniprot
B7ZLY8
resolver
uniprot
J3KNX4
resolver
uniprot
J3KQD6
resolver
uniprot
K7ES53
resolver
uniprot
Q13109
resolver
uniprot
Q5XKB9
resolver
uniprot
Q8N2I4
resolver
uniprot
Q96A67
resolver
uniprot_entry
J3KNX4_HUMAN
resolver
uniprot_entry
K7ES53_HUMAN
resolver
uniprot_entry
PWP3A_HUMAN
resolver
uniprot_sec
A1L489
resolver
uniprot_sec
B5ME02
resolver
uniprot_sec
B7ZLY8
resolver
uniprot_sec
J3KQD6
resolver
uniprot_sec
Q13109
resolver
uniprot_sec
Q5XKB9
resolver
uniprot_sec
Q8N2I4
resolver
uniprot_sec
Q96A67
resolver
amino_acid_sequence
MADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR
uniprot
proteins
function
FUNCTION: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. {ECO:0000269|PubMed:20347427}.
uniprot
proteins
mass_dalton
78636
uniprot
proteins
protein_family
PWWP3A family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20347427
uniprot
proteins
pubmed
21720545
uniprot
proteins
pubmed
7644523
uniprot
proteins
sequence_length
710
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20347427}. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
uniprot
proteins