Cdcp1
entrez
109332
canonical
uniprot
Q5U462
canonical
ensembl
ENSMUSG00000035498
resolver
ensp
ENSMUSP00000042057
resolver
enst
ENSMUST00000039229
resolver
genesymbol
Cdcp1
resolver
uniprot
Q810J0
resolver
uniprot
Q921M9
resolver
uniprot_entry
CDCP1_MOUSE
resolver
uniprot_sec
Q810J0
resolver
uniprot_sec
Q921M9
resolver
amino_acid_sequence
MAHSACGFSVALLGALLLGTARLLRGTEASEIALPQRSGVTVSIKLGNPALPVKICYIVMSRQHITELIIRPGERKSFTFSCSNPEKHFVLKIEKNIDCMSGPCPFGEVHLQPSTSELPILNRTFIWDVRAHKSIGLELQFATPRLRQIGPGESCADGVTHSISGHIDATEVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHRRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPGGFPEDELMTWQFVVPAHLRASVSFLNFNVSNCERKEERVEYYIPGSTTNPEVFRLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQRPQDESNKTYMVDLSRERTMSLTIEPRPVKHGRRFVPGCFVCLESRTCSTNVTLTAGSIHKISFLCDDLTRLWVNVEKTLSCLDHRYCYRQSFKLQVPDYILQLPVQLHDFSWKLLVPKDKLSLMLVPGQKLQQHTQERPCNTSFGYHVTSTTPGQDLYFGSFCSGGSIEKIQVKQNSSVTLRAYAPSFQQEVSKQGLIVSYTPYFKEEGIFTVTPDTKNKVYLRSPNWDRGLPALSSVSWNISVPSNQVACLTVLKERSGLACQSGRAFMIIQEQQSRAEEIFSLEEEVLPKPSFHHHSFWVNISNCSPMNGKQLDLLFWVTLTPRTVDLAVVIGAAGGGALLLFALVLIICFVKKKKKVDKGPAVGIYNGNVNTQMPQTQKFPKGRKDNDSHVYAVIEDTMVYGHLLQDSGGSFIQPEVDTYRPFQGPMGDCPPTPPPLFSRTPTAKFTAEELAPSSPPESESEPYTFSHPNKGEIGVRETDIPLLHTQGPVETEE
uniprot
proteins
function
FUNCTION: May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
uniprot
proteins
mass_dalton
92726
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5 (By similarity). {ECO:0000250}.; PTM: N-glycosylated. {ECO:0000250}.; PTM: A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on the N-terminal side. Converted to p80 by plasmin, a trypsin-like protease (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
833
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Its shedding may lead to a soluble peptide. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 667..687; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins