NANP
entrez
140838
canonical
uniprot
Q8TBE9
canonical
ensembl
ENSG00000170191
resolver
ensp
ENSP00000302441
resolver
enst
ENST00000304788
resolver
genesymbol
NANP
resolver
genesymbol_syn
C20orf147
resolver
genesymbol_syn
HDHD4
resolver
hgnc
HGNC:16140
resolver
uniprot
B3KP12
resolver
uniprot
Q5JYN8
resolver
uniprot
Q8TE97
resolver
uniprot
Q9Y3N0
resolver
uniprot_entry
NANP_HUMAN
resolver
uniprot_sec
B3KP12
resolver
uniprot_sec
Q5JYN8
resolver
uniprot_sec
Q8TE97
resolver
uniprot_sec
Q9Y3N0
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by calcium (PubMed:16237198). Inhibited by vanadate, sodium orthovanadate and phosphonate (PubMed:16237198, PubMed:23747226). {ECO:0000269|PubMed:16237198, ECO:0000269|PubMed:23747226}.
uniprot
proteins
amino_acid_sequence
MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCKVSMST
uniprot
proteins
ec_number
3.1.3.29
uniprot
proteins
function
FUNCTION: Catalyzes the dephosphorylation of N-acylneuraminate 9-phosphate (Neu5Ac-9-P) to N-acetylneuraminic acid (Neu5Ac or sialic acid) (PubMed:14235556, PubMed:16237198, PubMed:23747226). Can also use N-glycoloylneuraminate 9-phosphate as substrate (PubMed:14235556). {ECO:0000269|PubMed:14235556, ECO:0000269|PubMed:16237198, ECO:0000269|PubMed:23747226}.
uniprot
proteins
mass_dalton
27813
uniprot
proteins
pathway_participation
PATHWAY: Amino-sugar metabolism; N-acetylneuraminate biosynthesis.
uniprot
proteins
protein_family
HAD-like hydrolase superfamily
uniprot
proteins
protein_family
NANP family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14235556
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16237198
uniprot
proteins
pubmed
23747226
uniprot
proteins
sequence_length
248
uniprot
proteins