Sult1b1
entrez
64305
canonical
uniprot
P52847
canonical
ensembl
ENSRNOG00000001967
resolver
ensembl
ENSRNOG00055016907
resolver
ensembl
ENSRNOG00060012734
resolver
ensembl
ENSRNOG00065005362
resolver
ensp
ENSRNOP00000101178
resolver
ensp
ENSRNOP00055023128
resolver
ensp
ENSRNOP00060017091
resolver
ensp
ENSRNOP00065005509
resolver
enst
ENSRNOT00000134618
resolver
enst
ENSRNOT00055028714
resolver
enst
ENSRNOT00060021623
resolver
enst
ENSRNOT00065007916
resolver
genesymbol
Sult1b1
resolver
genesymbol_syn
St1b1
resolver
uniprot_entry
ST1B1_RAT
resolver
amino_acid_sequence
MGTAEDVFRKDLKIIHGYPMVYAFALGWEKIEEFQSRPCDIVIPTYPKSGTTWLSEIVDMVLNDGNVEKCKRDVITSKVPMLEQNVPGARRSGVELLKKTPSPRIIKTHLPIDLLPKSFWDNKCKMIYLARNGKDVAVSYYHFDLMNNIQPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREGHPILFLYYEDLKKNPKKEIKKIANFLDKTLDEHTLERIVHHTSFEVMKDNPLVNYTHLPTEIMDHSKSPFMRKGVVGDWKNYFTMTQSEKFDAIYKKKLSGTTLEFCTDIQSA
uniprot
proteins
ec_number
2.8.2.1
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3) (PubMed:12773305, PubMed:8530477). May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system (By similarity). {ECO:0000250|UniProtKB:O43704, ECO:0000269|PubMed:12773305, ECO:0000269|PubMed:8530477}.
uniprot
proteins
mass_dalton
34835
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
12773305
uniprot
proteins
pubmed
8033246
uniprot
proteins
pubmed
8530477
uniprot
proteins
pubmed
9443824
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:8530477}.
uniprot
proteins