Tmem38a
entrez
74166
canonical
uniprot
Q3TMP8
canonical
ensembl
ENSMUSG00000031791
resolver
ensp
ENSMUSP00000034244
resolver
ensp
ENSMUSP00000148388
resolver
ensp
ENSMUSP00000328390
resolver
ensp
ENSMUSP00000354668
resolver
ensp
ENSMUSP00000354669
resolver
enst
ENSMUST00000034244
resolver
enst
ENSMUST00000212763
resolver
genesymbol
Tmem38a
resolver
uniprot
A0A1D5RLJ0
resolver
uniprot
A5A6S4
resolver
uniprot
A7LBB7
resolver
uniprot
Q3TZB9
resolver
uniprot
Q91WL2
resolver
uniprot_entry
A0A1D5RLJ0_MOUSE
resolver
uniprot_entry
TM38A_MOUSE
resolver
uniprot_sec
A5A6S4
resolver
uniprot_sec
A7LBB7
resolver
uniprot_sec
Q3TZB9
resolver
uniprot_sec
Q91WL2
resolver
activity_regulation
ACTIVITY REGULATION: Channel activity is activated by a change of voltage within the sarcoplasmic reticulum lumen and blocked by luminal high Ca(2+) levels. {ECO:0000250|UniProtKB:A5A6S6}.
uniprot
proteins
amino_acid_sequence
MDLMSALSLGELALSFSRVPLFPVFDLSYFIVSIIYLKYEPGAVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKGSGVALLSNVEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFVFTMFMVSCKVFLTATHSHSSPFDILEGYICPVLFGATWGGDHHHDNHGAPHGMGLGTQHSGLPAKAKEELGEGSRKKKTKKAD
uniprot
proteins
function
FUNCTION: Intracellular monovalent cation channel required for maintenance of rapid intracellular calcium release. Acts as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. Opened by a change of voltage within the sarcoplasmic reticulum lumen. {ECO:0000250|UniProtKB:A5A6S6}.
uniprot
proteins
mass_dalton
33309
uniprot
proteins
protein_family
TMEM38 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17611541
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:A5A6S6}; Multi-pass membrane protein {ECO:0000250|UniProtKB:A5A6S6}. Nucleus membrane {ECO:0000250|UniProtKB:A5A6S6}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical;Name=1"; /evidence="ECO:0000255"; TRANSMEM 52..72; /note="Helical;Name=2"; /evidence="ECO:0000255"; TRANSMEM 86..106; /note="Helical;Name=3"; /evidence="ECO:0000255"; TRANSMEM 145..165; /note="Helical;Name=4"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical;Name=5"; /evidence="ECO:0000255"; TRANSMEM 210..230; /note="Helical;Name=6"; /evidence="ECO:0000255"; TRANSMEM 235..255; /note="Helical;Name=7"; /evidence="ECO:0000255
uniprot
proteins