CACNB1
entrez
782
canonical
uniprot
Q02641
canonical
ensembl
ENSG00000067191
resolver
ensp
ENSP00000345461
resolver
ensp
ENSP00000377840
resolver
ensp
ENSP00000377847
resolver
ensp
ENSP00000580792
resolver
genesymbol
CACNB1
resolver
genesymbol_syn
CACNLB1
resolver
hgnc
HGNC:1401
resolver
uniprot
A8K114
resolver
uniprot
O15331
resolver
uniprot
Q02639
resolver
uniprot
Q02640
resolver
uniprot
Q8N3X9
resolver
uniprot
Q9C085
resolver
uniprot
Q9UD79
resolver
uniprot_entry
CACB1_HUMAN
resolver
uniprot_sec
A8K114
resolver
uniprot_sec
O15331
resolver
uniprot_sec
Q02639
resolver
uniprot_sec
Q02640
resolver
uniprot_sec
Q8N3X9
resolver
uniprot_sec
Q9C085
resolver
uniprot_sec
Q9UD79
resolver
amino_acid_sequence
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR
uniprot
proteins
function
FUNCTION: Regulatory subunit of L-type calcium channels (PubMed:1309651, PubMed:15615847, PubMed:8107964). Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity). Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane (PubMed:15615847). Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit (PubMed:1309651). Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (PubMed:8107964). {ECO:0000250|UniProtKB:P19517, ECO:0000269|PubMed:1309651, ECO:0000269|PubMed:15615847, ECO:0000269|PubMed:8107964}.
uniprot
proteins
mass_dalton
65714
uniprot
proteins
protein_family
Calcium channel beta subunit family
uniprot
proteins
pubmed
10624822
uniprot
proteins
pubmed
1309651
uniprot
proteins
pubmed
1385409
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15615847
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
7916667
uniprot
proteins
pubmed
8107964
uniprot
proteins
pubmed
8395940
uniprot
proteins
pubmed
8905728
uniprot
proteins
sequence_length
598
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane, sarcolemma {ECO:0000305|PubMed:15615847}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19517}; Cytoplasmic side {ECO:0000250|UniProtKB:P19517}. Cell membrane {ECO:0000305|PubMed:1309651}; Peripheral membrane protein {ECO:0000305|PubMed:1309651}.
uniprot
proteins