Cacng4
entrez
54377
canonical
uniprot
Q9JJV4
canonical
ensembl
ENSMUSG00000020723
resolver
ensp
ENSMUSP00000021066
resolver
enst
ENSMUST00000021066
resolver
genesymbol
Cacng4
resolver
uniprot
A2AAU2
resolver
uniprot_entry
A2AAU2_MOUSE
resolver
uniprot_entry
CCG4_MOUSE
resolver
amino_acid_sequence
MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIYRGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQDAGFLQMHDFFQQDLKEGFHVSMLNRRTTPV
uniprot
proteins
function
FUNCTION: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization (PubMed:17880894). {ECO:0000250|UniProtKB:Q9UBN1, ECO:0000269|PubMed:17880894}.
uniprot
proteins
mass_dalton
36535
uniprot
proteins
protein_family
CACNG subfamily
uniprot
proteins
protein_family
PMP-22/EMP/MP20 family
uniprot
proteins
pubmed
10734232
uniprot
proteins
pubmed
11389205
uniprot
proteins
pubmed
17880894
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
327
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11389205}; Multi-pass membrane protein {ECO:0000269|PubMed:11389205}.
uniprot
proteins
transmembrane_region
TRANSMEM 10..30; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 108..128; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 137..157; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 187..207; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins