PDE4C
entrez
5143
canonical
uniprot
Q08493
canonical
ensembl
ENSG00000105650
resolver
ensembl
ENSG00000285188
resolver
ensp
ENSP00000262805
resolver
ensp
ENSP00000402091
resolver
ensp
ENSP00000439470
resolver
ensp
ENSP00000469696
resolver
ensp
ENSP00000470210
resolver
enst
ENST00000539010
resolver
genesymbol
PDE4C
resolver
genesymbol_syn
DPDE1
resolver
hgnc
HGNC:8782
resolver
uniprot
B3KTC4
resolver
uniprot
F6R4I1
resolver
uniprot
O43849
resolver
uniprot
P78505
resolver
uniprot
Q32MM7
resolver
uniprot
Q7KYS4
resolver
uniprot
Q9UN44
resolver
uniprot
Q9UN45
resolver
uniprot
Q9UN46
resolver
uniprot
Q9UPJ6
resolver
uniprot_entry
F6R4I1_HUMAN
resolver
uniprot_entry
O43849_HUMAN
resolver
uniprot_entry
P78505_HUMAN
resolver
uniprot_entry
PDE4C_HUMAN
resolver
uniprot_entry
Q32MM7_HUMAN
resolver
uniprot_entry
Q7KYS4_HUMAN
resolver
uniprot_sec
B3KTC4
resolver
uniprot_sec
Q9UN44
resolver
uniprot_sec
Q9UN45
resolver
uniprot_sec
Q9UN46
resolver
uniprot_sec
Q9UPJ6
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by rolipram. {ECO:0000269|PubMed:7843419}.
uniprot
proteins
amino_acid_sequence
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
uniprot
proteins
ec_number
3.1.4.53
uniprot
proteins
function
FUNCTION: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. {ECO:0000269|PubMed:17727341, ECO:0000269|PubMed:7843419}.
uniprot
proteins
mass_dalton
79902
uniprot
proteins
pathway_participation
PATHWAY: Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. {ECO:0000305|PubMed:7843419}.
uniprot
proteins
protein_family
Cyclic nucleotide phosphodiesterase family
uniprot
proteins
protein_family
PDE4 subfamily
uniprot
proteins
pubmed
10574328
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
17727341
uniprot
proteins
pubmed
7843419
uniprot
proteins
pubmed
8413254
uniprot
proteins
sequence_length
712
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000250|UniProtKB:Q3UEI1}.
uniprot
proteins