Ptger4
entrez
84023
canonical
uniprot
P43114
canonical
ensembl
ENSRNOG00000013240
resolver
ensp
ENSRNOP00000017886
resolver
ensp
ENSRNOP00000102242
resolver
enst
ENSRNOT00000017886
resolver
genesymbol
Ptger4
resolver
uniprot
A0A0G2JSM6
resolver
uniprot
O08728
resolver
uniprot_entry
A0A0G2JSM6_RAT
resolver
uniprot_entry
PE2R4_RAT
resolver
uniprot_sec
O08728
resolver
amino_acid_sequence
MSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMLRQFMRRTSLGTEQHHAAAAAAVASVACRGHAAASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPSVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDGSAQHCSESRRTSSAMSGHSRSFLSRELREISSTSHTLLYLPDLTESSLGGKNLLPGTHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSQREEPASKGNSLQVTFPSETLKLSEKCI
uniprot
proteins
function
FUNCTION: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
uniprot
proteins
mass_dalton
53366
uniprot
proteins
post_translational_modification
PTM: Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. {ECO:0000250}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
8185583
uniprot
proteins
pubmed
9537820
uniprot
proteins
sequence_length
488
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 20..43; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 56..79; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 97..115; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 136..160; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 185..211; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 271..298; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 316..335; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins