OTULINL
entrez
54491
canonical
uniprot
Q9NUU6
canonical
ensembl
ENSG00000145569
resolver
ensp
ENSP00000274217
resolver
enst
ENST00000274217
resolver
genesymbol
OTULINL
resolver
genesymbol_syn
FAM105A
resolver
hgnc
HGNC:25629
resolver
uniprot
Q53H50
resolver
uniprot
Q9H037
resolver
uniprot_entry
OTULL_HUMAN
resolver
uniprot_sec
Q53H50
resolver
uniprot_sec
Q9H037
resolver
amino_acid_sequence
MAATRSPTRARERERSGAPAAGSDQVHSWMLATSQALDTVWRMAKGFVMLAVSFLVAAICYFRRLHLYSGHKLKWWIGYLQRKFKRNLSVEAEVDLLSYCAREWKGETPRNKLMRKAYEELFWRHHIKCVRQVRRDNYDALRSVLFQIFSQGISFPSWMKEKDIVKLPEKLLFSQGCNWIQQYSFGPEKYTGSNVFGKLRKYVELLKTQWTEFNGIRDYHKRGSMCNTLFSDAILEYKLYEALKFIMLYQVTEVYEQMKTKKVIPSLFRLLFSRETSSDPLSFMMNHLNSVGDTCGLEQIDMFILGYSLEVKIKVFRLFKFNSRDFEVCYPEEPLRDWPEISLLTENDRHYHIPVF
uniprot
proteins
function
FUNCTION: Lacks deubiquitinase activity. {ECO:0000269|PubMed:31056421}.
uniprot
proteins
mass_dalton
42196
uniprot
proteins
mutagenesis
MUTAGEN 2..83; /note="Missing: Loss of membrane binding."; /evidence="ECO:0000269|PubMed:31056421"; MUTAGEN 139; /note="D->C: Fails to confer catalytic activity; when associated with N-352."; /evidence="ECO:0000269|PubMed:31056421"; MUTAGEN 352; /note="H->N: Fails to confer catalytic activity; when associated with C-139."; /evidence="ECO:0000269|PubMed:31056421
uniprot
proteins
protein_family
Otulin subfamily
uniprot
proteins
protein_family
Peptidase C65 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
23708998
uniprot
proteins
pubmed
31056421
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:31056421}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:31056421}; Peripheral membrane protein {ECO:0000269|PubMed:31056421}. Nucleus envelope {ECO:0000269|PubMed:31056421}.
uniprot
proteins