INIP
entrez
58493
canonical
uniprot
Q9NRY2
canonical
ensembl
ENSG00000148153
resolver
ensp
ENSP00000363353
resolver
ensp
ENSP00000363360
resolver
ensp
ENSP00000651123
resolver
ensp
ENSP00000651125
resolver
enst
ENST00000374236
resolver
genesymbol
INIP
resolver
genesymbol_syn
C9orf80
resolver
genesymbol_syn
SSBIP1
resolver
hgnc
HGNC:24994
resolver
uniprot
Q5VWJ7
resolver
uniprot
Q96E04
resolver
uniprot
Q9P090
resolver
uniprot
X6R8P6
resolver
uniprot_entry
SOSSC_HUMAN
resolver
uniprot_entry
X6R8P6_HUMAN
resolver
uniprot_sec
Q5VWJ7
resolver
uniprot_sec
Q96E04
resolver
uniprot_sec
Q9P090
resolver
amino_acid_sequence
MAANSSGQGFQNKNRVAILAELDKEKRKLLMQNQSSTNHPGASIALSRPSLNKDFRDHAEQQHIAAQQKAALQHAHAHSSGYFITQDSAFGNLILPVLPRLDPE
uniprot
proteins
function
FUNCTION: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. {ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}.
uniprot
proteins
mass_dalton
11425
uniprot
proteins
protein_family
SOSS-C family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19605351
uniprot
proteins
pubmed
19683501
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
104
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}. Note=Localizes to nuclear foci following DNA damage.
uniprot
proteins