Pde7b
entrez
29863
canonical
uniprot
Q9QXQ1
canonical
ensembl
ENSMUSG00000019990
resolver
ensp
ENSMUSP00000020165
resolver
ensp
ENSMUSP00000132378
resolver
enst
ENSMUST00000020165
resolver
enst
ENSMUST00000169404
resolver
genesymbol
Pde7b
resolver
uniprot
A1L3T2
resolver
uniprot
E9Q0W7
resolver
uniprot
Q8CBS2
resolver
uniprot_entry
E9Q0W7_MOUSE
resolver
uniprot_entry
PDE7B_MOUSE
resolver
uniprot_entry
Q8CBS2_MOUSE
resolver
uniprot_sec
A1L3T2
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by dipyridamole, IBMX and SCH 51866. Insensitive to zaprinast, rolipram, and milrinone. {ECO:0000269|PubMed:10872825}.
uniprot
proteins
amino_acid_sequence
MSCLMVERCGEVLFESPEQSVKCVCMLGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGSGQDLAGPAPETLEQTEGATP
uniprot
proteins
ec_number
3.1.4.53
uniprot
proteins
function
FUNCTION: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10872825). May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (By similarity). {ECO:0000250|UniProtKB:Q9NP56, ECO:0000269|PubMed:10872825}.
uniprot
proteins
mass_dalton
51337
uniprot
proteins
pathway_participation
PATHWAY: Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. {ECO:0000305|PubMed:10872825}.
uniprot
proteins
protein_family
Cyclic nucleotide phosphodiesterase family
uniprot
proteins
protein_family
PDE7 subfamily
uniprot
proteins
pubmed
10618442
uniprot
proteins
pubmed
10872825
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
446
uniprot
proteins