BAIAP2L1
entrez
55971
canonical
uniprot
Q9UHR4
canonical
ensembl
ENSG00000006453
resolver
ensp
ENSP00000005260
resolver
enst
ENST00000005260
resolver
genesymbol
BAIAP2L1
resolver
genesymbol_syn
IRTKS
resolver
hgnc
HGNC:21649
resolver
uniprot
A4D268
resolver
uniprot
Q75L21
resolver
uniprot
Q75L22
resolver
uniprot
Q96CV4
resolver
uniprot
Q9H5F5
resolver
uniprot
Q9Y2M8
resolver
uniprot_entry
BI2L1_HUMAN
resolver
uniprot_sec
A4D268
resolver
uniprot_sec
Q75L21
resolver
uniprot_sec
Q75L22
resolver
uniprot_sec
Q96CV4
resolver
uniprot_sec
Q9H5F5
resolver
uniprot_sec
Q9Y2M8
resolver
amino_acid_sequence
MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGTAKPPFLSGENPFATVKLRPTVTNDRSAPIIR
uniprot
proteins
function
FUNCTION: May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. {ECO:0000269|PubMed:17430976, ECO:0000269|PubMed:19366662, ECO:0000269|PubMed:22921828}.
uniprot
proteins
mass_dalton
56883
uniprot
proteins
mutagenesis
MUTAGEN 141; /note="K->E: Loss ability to induce the formation of actin clusters; when associated with K-142; R-145 and K-146."; /evidence="ECO:0000269|PubMed:17430976"; MUTAGEN 142; /note="K->E: Loss ability to induce the formation of actin clusters; when associated with K-141; R-145 and K-146."; /evidence="ECO:0000269|PubMed:17430976"; MUTAGEN 145; /note="R->E: Loss ability to induce the formation of actin clusters; when associated with K-141; K-142 and K-146."; /evidence="ECO:0000269|PubMed:17430976"; MUTAGEN 146; /note="K->E: Loss ability to induce the formation of actin clusters; when associated with K-141; K-142 and R-145."; /evidence="ECO:0000269|PubMed:17430976"; MUTAGEN 488..511; /note="Missing: Loss ability to induce the formation of actin clusters; induce the formation of long filopodia."; /evidence="ECO:0000269|PubMed:17430976
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine in response to insulin. {ECO:0000269|PubMed:17430976}.
uniprot
proteins
pubmed
10931946
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17430976
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19366662
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19807924
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21098279
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22921828
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
511
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19366662}. Note=Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
uniprot
proteins