ADGRL4
entrez
64123
canonical
uniprot
Q9HBW9
canonical
ensembl
ENSG00000162618
resolver
ensp
ENSP00000359778
resolver
enst
ENST00000370742
resolver
genesymbol
ADGRL4
resolver
genesymbol_syn
ELTD1
resolver
genesymbol_syn
ETL
resolver
hgnc
HGNC:20822
resolver
uniprot
B1AR71
resolver
uniprot
Q5KU34
resolver
uniprot_entry
AGRL4_HUMAN
resolver
uniprot_sec
B1AR71
resolver
uniprot_sec
Q5KU34
resolver
amino_acid_sequence
MKRLPLLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVCIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR
uniprot
proteins
function
FUNCTION: Endothelial orphan receptor that acts as a key regulator of angiogenesis. {ECO:0000269|PubMed:23871637}.
uniprot
proteins
mass_dalton
77811
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000269|PubMed:23871637}.; PTM: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. {ECO:0000250|UniProtKB:Q9ESC1}.
uniprot
proteins
protein_family
Adhesion G protein-coupled receptor (ADGR) subfamily
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
11050079
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
23871637
uniprot
proteins
pubmed
25713288
uniprot
proteins
sequence_length
690
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23871637}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 433..453; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 461..481; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 500..520; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 533..553; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 574..594; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 619..639; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 647..667; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins