Orc4
entrez
295596
canonical
uniprot
Q6P9Z8
canonical
ensembl
ENSRNOG00000005021
resolver
ensembl
ENSRNOG00055001565
resolver
ensembl
ENSRNOG00060032221
resolver
ensembl
ENSRNOG00065008296
resolver
ensp
ENSRNOP00000006937
resolver
ensp
ENSRNOP00000077265
resolver
ensp
ENSRNOP00000085949
resolver
ensp
ENSRNOP00055001892
resolver
ensp
ENSRNOP00060046208
resolver
ensp
ENSRNOP00065009734
resolver
enst
ENSRNOT00000006937
resolver
enst
ENSRNOT00000103065
resolver
enst
ENSRNOT00055002515
resolver
enst
ENSRNOT00060055865
resolver
enst
ENSRNOT00065013163
resolver
genesymbol
Orc4
resolver
genesymbol_syn
Orc4l
resolver
uniprot
A0A8I5Y5K9
resolver
uniprot
A0A8L2Q2Z8
resolver
uniprot_entry
A0A8I5Y5K9_RAT
resolver
uniprot_entry
A0A8L2Q2Z8_RAT
resolver
uniprot_entry
ORC4_RAT
resolver
amino_acid_sequence
MSNRKSKNNIHAECLSQVQRILRERFCHHTPHSNLFGVQVQYKHLIELLKRTAIYGESNSLLIVGPRGSGKTTLLNHALKELMQIGDMSENVLQVHLNGLLQTNDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALQKGNRTSSCPVIFILDEFDLFAHQKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKIFAEKWNENAHCLSEDSTVLEVLQKHFNVNKNLQSLHMLLMLALNRVTVTHPFMTSADLMEAQHLCSLDAKASIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL
uniprot
proteins
function
FUNCTION: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
50105
uniprot
proteins
protein_family
ORC4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
434
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins