Depdc1a
entrez
76131
canonical
uniprot
Q8CIG0
canonical
ensembl
ENSMUSG00000028175
resolver
ensp
ENSMUSP00000029825
resolver
ensp
ENSMUSP00000101656
resolver
ensp
ENSMUSP00000113216
resolver
enst
ENSMUST00000120272
resolver
genesymbol
Depdc1a
resolver
uniprot
D3Z6J1
resolver
uniprot
Q8BHF1
resolver
uniprot
Q99JN3
resolver
uniprot_entry
D3Z6J1_MOUSE
resolver
uniprot_entry
DEP1A_MOUSE
resolver
uniprot_sec
Q8BHF1
resolver
uniprot_sec
Q99JN3
resolver
amino_acid_sequence
MERQGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCFTAVEAIDWLYDLLRSNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSESLDDNNQLFRFPATSPLKTFPQRHTEIKKTNTEYFSKDKDGIFKLRNLSQKTSKKRGLHFSQENTEKINHERITNEDLEIAPDNQEISQEDVEEVWRYVIMIYLQTILSLPSIEELLNPNQVIPQYIMYNMANTSKHGVVILQDKSDDLPHWVLSAMKCLANWPRSNDTNNLTYVGFERDVFKTIADYFLNLPEPLLTFEYYELFVNILVVCGYITVSDRTSGIHKIQDDPRSSKIHDLSNLNSFKSTECLLLSLLYKDKSNEELDSTKRLQRNDQGFQERCAKKMQLDNLRNRRASANDIMGGSCHNLIGLSNTNALSSNIKPRCSSLEGIVDRPVNSSEKKSSIFYQSVLNIEEQNSKQSLVSAPKQTPLFNLHSDENAQQPHCVGFNRTSALTVQDQEELCNEKYKSKQLCRSQSLLLRSSTRQNSCINKPVAEIIMKPNVGQGSTSELGESSTTINKRLCKSTIELSEKSLPPAASVLTGTQSLLQPHLERVAINALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHEQIGTRSLMINTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQVPTYLQAAVEKHLDYIKKGNVKNHGDGLVVPLPTYSYCKQISAKEFDEQKISTSQAAIAELLENIVRSKSLSLKEKRRKLKQKEYPLIYQKRFPTTESEAALFDDKPTIKQPMLNLRNPKLHSLRY
uniprot
proteins
function
FUNCTION: May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
92201
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
804
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Colocalizes with ZNF224 at the nucleus. {ECO:0000250}.
uniprot
proteins