Prrt1
entrez
406167
canonical
uniprot
Q6MG82
canonical
ensembl
ENSRNOG00000000433
resolver
ensembl
ENSRNOG00055006687
resolver
ensembl
ENSRNOG00060007386
resolver
ensembl
ENSRNOG00065027769
resolver
ensp
ENSRNOP00000000495
resolver
ensp
ENSRNOP00000098032
resolver
ensp
ENSRNOP00055008498
resolver
ensp
ENSRNOP00060009156
resolver
ensp
ENSRNOP00065039271
resolver
enst
ENSRNOT00000000495
resolver
enst
ENSRNOT00000120342
resolver
enst
ENSRNOT00055010914
resolver
enst
ENSRNOT00060012140
resolver
enst
ENSRNOT00065047862
resolver
genesymbol
Prrt1
resolver
genesymbol_syn
Ng5
resolver
uniprot
A0ABK0KW16
resolver
uniprot_entry
A0ABK0KW16_RAT
resolver
uniprot_entry
PRRT1_RAT
resolver
amino_acid_sequence
MSSEKSGLPDSVPHTSPPPYNAPQPPAEPPIPPPQTAPSSHHHHHHHYHQSGTATLPRLGAGGLASAAAGAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMPPDPYLQETRFEGPLPPPPPAAAAPPPPAPAPTAQAPGFVVPTHAGAVGTLPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYASGTPGGPGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGIAAMVLCTILTVVIIIAAQHHENYWDP
uniprot
proteins
function
FUNCTION: Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression. {ECO:0000250|UniProtKB:O35449}.
uniprot
proteins
mass_dalton
31389
uniprot
proteins
protein_family
CD225/Dispanin family
uniprot
proteins
pubmed
15060004
uniprot
proteins
pubmed
22363774
uniprot
proteins
pubmed
22632720
uniprot
proteins
pubmed
26660156
uniprot
proteins
sequence_length
306
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26660156, ECO:0000305|PubMed:22632720}; Single-pass type II membrane protein {ECO:0000305|PubMed:26660156}. Synapse {ECO:0000305|PubMed:22632720}.
uniprot
proteins
transmembrane_region
TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins