Gpsm1
entrez
67839
canonical
uniprot
Q6IR34
canonical
ensembl
ENSMUSG00000026930
resolver
ensp
ENSMUSP00000065000
resolver
ensp
ENSMUSP00000067964
resolver
ensp
ENSMUSP00000077686
resolver
ensp
ENSMUSP00000109769
resolver
ensp
ENSMUSP00000115680
resolver
enst
ENSMUST00000114134
resolver
genesymbol
Gpsm1
resolver
genesymbol_syn
Ags3
resolver
uniprot
A2AIV3
resolver
uniprot
A2AIX7
resolver
uniprot
A2AIX8
resolver
uniprot
A2AIX9
resolver
uniprot
Q61366
resolver
uniprot
Q8BUK4
resolver
uniprot
Q8BX78
resolver
uniprot
Q8R0R9
resolver
uniprot_entry
A2AIV3_MOUSE
resolver
uniprot_entry
GPSM1_MOUSE
resolver
uniprot_sec
A2AIX7
resolver
uniprot_sec
A2AIX8
resolver
uniprot_sec
A2AIX9
resolver
uniprot_sec
Q61366
resolver
uniprot_sec
Q8BUK4
resolver
uniprot_sec
Q8BX78
resolver
uniprot_sec
Q8R0R9
resolver
amino_acid_sequence
MASPAPPVAEELPGPASRRLYSRMEASCLELALEGERLCKAGDFKAGVAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLKEYARALQFHKHDLLLARTIGDRMGEAKASGNLGNTLKVLGRFDEAIVCCQRHLDIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAAQDPGHLPPDVRETLHRASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDVAAEHYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLVIAQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLQISQEIGDRNGELTARMNIAHLQLALGRLTSPAAAEKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLDREQNGETHHTGDWRGPGRDSLPLPMRSRKYQEGPDAIERRPREGSHSPLDSADVRVQVPRTGIPRAPSSDEECFFDLLSKFQSSRMDDQRCPLEEGQAGAAEATAAPSVEDRAAQSSVTASPQTEEFFDLIASSQSRRLDDQRASVGSLPGLRITLNNVGHLRGDGDAQEPGDEFFNMLIKYQSSRIDDQRCPPPDVLPRGPTMPDEDFFSLIQRVQAKRMDEQRVDLAGSPEQEASGLPDPQQQCPPGAS
uniprot
proteins
function
FUNCTION: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. {ECO:0000269|PubMed:16009138}.
uniprot
proteins
mass_dalton
74362
uniprot
proteins
post_translational_modification
PTM: Phosphorylation regulates interaction with G(i/o) alpha. {ECO:0000269|PubMed:12719437}.
uniprot
proteins
protein_family
GPSM family
uniprot
proteins
pubmed
12719437
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16009138
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
673
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
uniprot
proteins