Osbp2
entrez
74309
canonical
uniprot
Q5QNQ6
canonical
ensembl
ENSMUSG00000020435
resolver
ensp
ENSMUSP00000068652
resolver
ensp
ENSMUSP00000099156
resolver
ensp
ENSMUSP00000100015
resolver
ensp
ENSMUSP00000184574
resolver
ensp
ENSMUSP00000184577
resolver
ensp
ENSMUSP00000184582
resolver
enst
ENSMUST00000070552
resolver
enst
ENSMUST00000102950
resolver
genesymbol
Osbp2
resolver
genesymbol_syn
orp4
resolver
uniprot
F8WGT8
resolver
uniprot
Q6PE09
resolver
uniprot
Q8CF21
resolver
uniprot
Q8K0C7
resolver
uniprot_entry
F8WGT8_MOUSE
resolver
uniprot_entry
OSBP2_MOUSE
resolver
uniprot_entry
Q6PE09_MOUSE
resolver
uniprot_entry
Q8K0C7_MOUSE
resolver
uniprot_sec
Q8CF21
resolver
amino_acid_sequence
MGKAAALSRGGGCAGRSRGLSSLFTVVPCLSCHTAAPGMNSSAFGSGPASKPQLQPVQAPERELLSKQVCQPISEPASRSEPGSQTTSVPRPSGVGQESELQGLWPGSENGTRSVSIIKASPELAMPSPLQSTVGSLPVTKPESKLVPKTQSFLRQGQAKISVGTPVSGIGVQMVSPPLDSYKGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRATINLASTHFETEDSCGILLCNGARTYHLKASSEVDRQHWITALELAKAKAIRVMKTQSDDSGDDDEEPAAPADNSELHHTLKTLSLKLNDLSTCNDLIAKHGAALQRSLNELDSLKIPSECGEKLKVVNERATLFRITSNAMINACRDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLERAFCNTPGGPASSSKSFSEGSFLTSKGENSEEDEDTEYFDAMEDSTSFITVVTEAKEDRKPESGPGTTTVDWTSADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEANTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF
uniprot
proteins
function
FUNCTION: Mediates the bidirectional lipid exchange between intracellular compartments and the plasma membrane, delivering cholesterol to the plasma membrane while transferring PI(4,5)P(2) to internal organelles, thereby modulating membrane lipid composition and associated signaling pathways (By similarity). Binds 7-ketocholesterol (By similarity). Acts during spermatid development where its function is required prior to the removal of cytoplasm from the sperm head (PubMed:24245814). {ECO:0000250|UniProtKB:Q969R2, ECO:0000269|PubMed:24245814}.
uniprot
proteins
mass_dalton
101353
uniprot
proteins
protein_family
OSBP family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24245814
uniprot
proteins
pubmed
38236177
uniprot
proteins
sequence_length
908
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q969R2}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q969R2}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:24245814}. Note=Localizes to the equatorial segment of the acrosome following cytoplasmic removal in the developing spermatid. {ECO:0000269|PubMed:24245814}.
uniprot
proteins