DUSP16
entrez
80824
canonical
uniprot
Q9BY84
canonical
ensembl
ENSG00000111266
resolver
ensembl
ENSG00000280962
resolver
ensp
ENSP00000298573
resolver
ensp
ENSP00000547493
resolver
ensp
ENSP00000547496
resolver
ensp
ENSP00000547498
resolver
genesymbol
DUSP16
resolver
genesymbol_syn
KIAA1700
resolver
genesymbol_syn
MKP7
resolver
hgnc
HGNC:17909
resolver
uniprot
Q547C7
resolver
uniprot
Q96QS2
resolver
uniprot
Q9C0G3
resolver
uniprot_entry
DUS16_HUMAN
resolver
uniprot_sec
Q547C7
resolver
uniprot_sec
Q96QS2
resolver
uniprot_sec
Q9C0G3
resolver
amino_acid_sequence
MAHEMIGTQIVTERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYKPSTTLDGTNKLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKRLHSVRTSSSGTAQRSLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKGWHSDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRRQKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSMEIIEVS
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2. {ECO:0000269|PubMed:11489891, ECO:0000269|PubMed:15888437}.
uniprot
proteins
mass_dalton
73102
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at Ser-446 by MAPK1/ERK2, which prevents its degradation, and thereby stabilizes it and blocks JNK MAPK activity. {ECO:0000269|PubMed:12794087}.; PTM: (Microbial infection) Acetylated at Lys-55 by the M.tuberculosis Eis protein; this leads to the inhibition of JNK-dependent autophagy, phagosome maturation, and ROS (reactive oxygen species) generation for enhanced intracellular survival of M.tuberculosis. {ECO:0000269|PubMed:22547814}.
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
11214970
uniprot
proteins
pubmed
11489891
uniprot
proteins
pubmed
12794087
uniprot
proteins
pubmed
14586399
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15888437
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
22547814
uniprot
proteins
sequence_length
665
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Cytoplasmic vesicle. Note=After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
uniprot
proteins