GKAP1
entrez
80318
canonical
uniprot
Q5VSY0
canonical
ensembl
ENSG00000165113
resolver
ensp
ENSP00000365544
resolver
ensp
ENSP00000365550
resolver
ensp
ENSP00000632746
resolver
ensp
ENSP00000632753
resolver
genesymbol
GKAP1
resolver
genesymbol_syn
GKAP42
resolver
hgnc
HGNC:17496
resolver
uniprot
Q96LI0
resolver
uniprot
Q9BYI1
resolver
uniprot
Q9BYI2
resolver
uniprot
Q9H225
resolver
uniprot_entry
GKAP1_HUMAN
resolver
uniprot_sec
Q96LI0
resolver
uniprot_sec
Q9BYI1
resolver
uniprot_sec
Q9BYI2
resolver
uniprot_sec
Q9H225
resolver
amino_acid_sequence
MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQCR
uniprot
proteins
function
FUNCTION: Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation. {ECO:0000250|UniProtKB:Q9JMB0}.
uniprot
proteins
mass_dalton
42078
uniprot
proteins
protein_family
GKAP1 family
uniprot
proteins
pubmed
10671526
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16015647
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
366
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q9JMB0}.
uniprot
proteins