Klf8
entrez
245671
canonical
uniprot
Q8BLM0
canonical
ensembl
ENSMUSG00000041649
resolver
ensp
ENSMUSP00000044317
resolver
ensp
ENSMUSP00000108193
resolver
ensp
ENSMUSP00000313647
resolver
ensp
ENSMUSP00000313648
resolver
ensp
ENSMUSP00000313649
resolver
ensp
ENSMUSP00000313650
resolver
ensp
ENSMUSP00000335841
resolver
ensp
ENSMUSP00000335842
resolver
ensp
ENSMUSP00000335846
resolver
enst
ENSMUST00000039545
resolver
enst
ENSMUST00000112574
resolver
genesymbol
Klf8
resolver
uniprot_entry
KLF8_MOUSE
resolver
amino_acid_sequence
MDKFIDNMDVRIKSESGSMQVFKQVTGPVPTRDPSARADRRNMTSPSFLAASPMENPALFNDIKIEPPEELLESDFNMPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPPTAPQAIMVPTSADTVTSAAIPTVLTPGSILASSQGTGGQPILHVIHTIPSVSLPNKMSGLKTIPLVVQSLPMVYTSLPTDGSPAAITVPLIGGDGKSAGSVKVDPASMCPLEFPSDSDESAIESGSSALQSLQGFHHEPATMVHMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM
uniprot
proteins
function
FUNCTION: Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK) (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
38845
uniprot
proteins
post_translational_modification
PTM: Sumoylation at Lys-64 represses transcriptional activity and reduces cell cycle progression into the G(1) phase. Has no effect on subcellular location.
uniprot
proteins
protein_family
Sp1 C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins