MMP12
entrez
4321
canonical
uniprot
P39900
canonical
ensembl
ENSG00000262406
resolver
ensp
ENSP00000458585
resolver
enst
ENST00000571244
resolver
genesymbol
MMP12
resolver
genesymbol_syn
HME
resolver
hgnc
HGNC:7158
resolver
uniprot
B2R9X8
resolver
uniprot
B7ZLF6
resolver
uniprot
Q2M1L9
resolver
uniprot_entry
MMP12_HUMAN
resolver
uniprot_sec
B2R9X8
resolver
uniprot_sec
B7ZLF6
resolver
uniprot_sec
Q2M1L9
resolver
amino_acid_sequence
MKFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
uniprot
proteins
ec_number
3.4.24.65
uniprot
proteins
function
FUNCTION: May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
uniprot
proteins
mass_dalton
54002
uniprot
proteins
protein_family
Peptidase M10A family
uniprot
proteins
pubmed
11575928
uniprot
proteins
pubmed
11575929
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8226919
uniprot
proteins
pubmed
9115292
uniprot
proteins
sequence_length
470
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000305}.
uniprot
proteins