PSMF1
entrez
9491
canonical
uniprot
Q92530
canonical
ensembl
ENSG00000125818
resolver
ensp
ENSP00000246015
resolver
ensp
ENSP00000327704
resolver
ensp
ENSP00000338039
resolver
ensp
ENSP00000499011
resolver
ensp
ENSP00000765653
resolver
ensp
ENSP00000765654
resolver
enst
ENST00000246015
resolver
enst
ENST00000333082
resolver
enst
ENST00000335877
resolver
enst
ENST00000652336
resolver
genesymbol
PSMF1
resolver
hgnc
HGNC:9571
resolver
uniprot
A0A140VJT2
resolver
uniprot
A0AVQ9
resolver
uniprot
B4DXW9
resolver
uniprot
D3DVW3
resolver
uniprot
Q5QPM7
resolver
uniprot
Q9H4I1
resolver
uniprot_entry
A0A140VJT2_HUMAN
resolver
uniprot_entry
B4DXW9_HUMAN
resolver
uniprot_entry
PSMF1_HUMAN
resolver
uniprot_entry
Q5QPM7_HUMAN
resolver
uniprot_sec
A0AVQ9
resolver
uniprot_sec
D3DVW3
resolver
uniprot_sec
Q9H4I1
resolver
amino_acid_sequence
MAGLEVLFASAAPAITCRQDALVCFLHWEVVTHGYFGLGVGDQPGPNDKKSELLPAGWNNNKDLYVLRYEYKDGSRKLLVKAITVESSMILNVLEYGSQQVADLTLNLDDYIDAEHLGDFHRTYKNSEELRSRIVSGIITPIHEQWEKANVSSPHREFPPATAREVDPLRIPPHHPHTSRQPPWCDPLGPFVVGGEDLDPFGPRRGGMIVDPLRSGFPRALIDPSSGLPNRLPPGAVPPGARFDPFGPIGTSPPGPNPDHLPPPGYDDMYL
uniprot
proteins
function
FUNCTION: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. {ECO:0000269|PubMed:10764772}.
uniprot
proteins
mass_dalton
29817
uniprot
proteins
mutagenesis
MUTAGEN 6; /note="V->R: Abolishes homodimerization."; /evidence="ECO:0000269|PubMed:18495667"; MUTAGEN 83; /note="I->E: Abolishes interaction with FBXO7, but has no effect on homodimerization; when associated with E-90."; /evidence="ECO:0000269|PubMed:18495667"; MUTAGEN 90; /note="I->E: Abolishes interaction with FBXO7, but has no effect on homodimerization; when associated with E-83."; /evidence="ECO:0000269|PubMed:18495667
uniprot
proteins
protein_family
Proteasome inhibitor PI31 family
uniprot
proteins
pubmed
10764772
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18495667
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18495667}. Endoplasmic reticulum {ECO:0000269|PubMed:18495667}.
uniprot
proteins