POLR2F
entrez
5435
canonical
uniprot
P61218
canonical
ensembl
ENSG00000100142
resolver
ensp
ENSP00000385725
resolver
ensp
ENSP00000403852
resolver
ensp
ENSP00000406826
resolver
ensp
ENSP00000475343
resolver
ensp
ENSP00000769007
resolver
ensp
ENSP00000769009
resolver
enst
ENST00000407936
resolver
enst
ENST00000442738
resolver
enst
ENST00000443002
resolver
genesymbol
POLR2F
resolver
genesymbol_syn
POLRF
resolver
hgnc
HGNC:9193
resolver
uniprot
B0QYL9
resolver
uniprot
F8WC47
resolver
uniprot
P41584
resolver
uniprot
Q6IAY3
resolver
uniprot_entry
B0QYL9_HUMAN
resolver
uniprot_entry
F8WC47_HUMAN
resolver
uniprot_entry
RPAB2_HUMAN
resolver
uniprot_sec
P41584
resolver
uniprot_sec
Q6IAY3
resolver
amino_acid_sequence
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD
uniprot
proteins
function
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPABC2 is part of the clamp element and together with parts of POLR2A/RPB1 and POLR2B/RPB2 forms a pocket to which the POLR2D/RPB4-POLR2G/RPB7 subcomplex binds. {ECO:0000250|UniProtKB:P20435, ECO:0000269|PubMed:20413673, ECO:0000269|PubMed:27193682, ECO:0000269|PubMed:30190596, ECO:0000269|PubMed:34671025, ECO:0000269|PubMed:34887565, ECO:0000269|PubMed:36271492, ECO:0000269|PubMed:9852112}.
uniprot
proteins
mass_dalton
14478
uniprot
proteins
protein_family
Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family
uniprot
proteins
pubmed
10542096
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20413673
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
27193682
uniprot
proteins
pubmed
30190596
uniprot
proteins
pubmed
33335104
uniprot
proteins
pubmed
33558764
uniprot
proteins
pubmed
33558766
uniprot
proteins
pubmed
33674783
uniprot
proteins
pubmed
34671025
uniprot
proteins
pubmed
34675218
uniprot
proteins
pubmed
34887565
uniprot
proteins
pubmed
36271492
uniprot
proteins
pubmed
7803819
uniprot
proteins
pubmed
8786150
uniprot
proteins
pubmed
9852112
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:33335104, ECO:0000269|PubMed:9852112}. Nucleus, nucleolus {ECO:0000305|PubMed:34887565, ECO:0000305|PubMed:36271492}.
uniprot
proteins