Ier3ip1
entrez
127566412
canonical
uniprot
P85007
canonical
ensembl
ENSRNOG00000043171
resolver
ensembl
ENSRNOG00055013578
resolver
ensembl
ENSRNOG00060014687
resolver
ensembl
ENSRNOG00065023274
resolver
ensp
ENSRNOP00000080458
resolver
ensp
ENSRNOP00055018897
resolver
ensp
ENSRNOP00060019999
resolver
ensp
ENSRNOP00065032370
resolver
enst
ENSRNOT00000119462
resolver
enst
ENSRNOT00055023283
resolver
enst
ENSRNOT00060025107
resolver
enst
ENSRNOT00065039791
resolver
genesymbol
Ier3ip1
resolver
uniprot_entry
IR3IP_RAT
resolver
amino_acid_sequence
MAFTLYSLMQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLLNLIRSVRTVMRVPLIIVNSITIVLLLLFG
uniprot
proteins
function
FUNCTION: Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size. Required for secretion of extracellular matrix proteins. Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors (By similarity). Acts as a regulator of the unfolded protein response (UPR) (By similarity). {ECO:0000250|UniProtKB:Q9CR20, ECO:0000250|UniProtKB:Q9Y5U9}.
uniprot
proteins
mass_dalton
8999
uniprot
proteins
protein_family
YOS1 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
82
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Y5U9}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 2..22; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 62..82; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins