Ccdc38
entrez
237465
canonical
uniprot
Q8CDN8
canonical
ensembl
ENSMUSG00000036168
resolver
ensp
ENSMUSP00000089860
resolver
ensp
ENSMUSP00000150407
resolver
ensp
ENSMUSP00000355597
resolver
genesymbol
Ccdc38
resolver
uniprot
Q8CDD6
resolver
uniprot
Q8CDE1
resolver
uniprot_entry
CCD38_MOUSE
resolver
uniprot_sec
Q8CDD6
resolver
uniprot_sec
Q8CDE1
resolver
amino_acid_sequence
MASQMHTSISSGDEGKDAVLKKERPYKIFFKDLFVFKENEIAARKKERMKNHSMKIYQKTTFSSRMKSRSHLGQLAFFADAGSSSYERLGLDPTLILRLTEGADRKRTVHEFINDQRDRFLLEYTVSTKKKTIKRFERLIAIKENQLKKAEKKLQDDALSFEEFLRENDQRSVDALKMAAQETINKLQMTSELKKASMEVQSIKSDIAKTEFLLKEYMKYGFFLLKLSPKQWQIQQSQKRAQSSKSNHILPKILEKFSINTAKGDNSIDSDKMSVSEEWSSRRGSQGGRHGKHTLGQDSRKSSGFTRPESMASEDSLEYFLEDELVEFDLLPEIYFKEPEELLQVFTELEEQNLTLVQYSQDVDENLEDVNKREKFIQDKINNNISFLLEHKHMLRMNCEREEEKAAELELRSRLFSFGEFNSDAQEKLIDSLSKKINQVYRVCIGDAEVGSLNAVQKLVKVESRLVELSDLIESIPREHVEAIERLKQKERRQKLREEKMKEKQRHQEERLKAALERAVAQPKKKLGRRLIYRSKPQSADKQELLLVSDTRSKSQDEEYFFS
uniprot
proteins
function
FUNCTION: Essential for male fertility (PubMed:35587122, PubMed:37709195). Required for sperm flagellum biogenesis (PubMed:35587122, PubMed:37709195). Also required for acrosome biogenesis (PubMed:37709195). Required for the attachment of developing acrosomes to the nucleus during spermiogenesis and may be involved in the transport of fibrous sheath components (PubMed:37709195). {ECO:0000269|PubMed:35587122, ECO:0000269|PubMed:37709195}.
uniprot
proteins
mass_dalton
65835
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
27278724
uniprot
proteins
pubmed
35587122
uniprot
proteins
pubmed
37709195
uniprot
proteins
pubmed
38038747
uniprot
proteins
sequence_length
563
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q502W7}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:35587122}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:35587122}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:35587122}. Note=Localizes to the sperm flagellum, manchette and the perinuclear region of the sperm head. {ECO:0000269|PubMed:35587122}.
uniprot
proteins