PPEF1
entrez
5475
canonical
uniprot
O14829
canonical
ensembl
ENSG00000086717
resolver
ensp
ENSP00000341892
resolver
ensp
ENSP00000354871
resolver
ensp
ENSP00000419273
resolver
ensp
ENSP00000508824
resolver
ensp
ENSP00000509616
resolver
ensp
ENSP00000509623
resolver
ensp
ENSP00000578241
resolver
ensp
ENSP00000578242
resolver
enst
ENST00000496616
resolver
genesymbol
PPEF1
resolver
genesymbol_syn
PPEF
resolver
genesymbol_syn
PPP7C
resolver
hgnc
HGNC:9243
resolver
uniprot
A0A8I5KXD3
resolver
uniprot
A6NHP4
resolver
uniprot
A8K348
resolver
uniprot
B7Z6R7
resolver
uniprot
O15253
resolver
uniprot
Q9NU21
resolver
uniprot
Q9UJH0
resolver
uniprot_entry
A0A8I5KXD3_HUMAN
resolver
uniprot_entry
B7Z6R7_HUMAN
resolver
uniprot_entry
PPE1_HUMAN
resolver
uniprot_sec
A6NHP4
resolver
uniprot_sec
A8K348
resolver
uniprot_sec
O15253
resolver
uniprot_sec
Q9NU21
resolver
uniprot_sec
Q9UJH0
resolver
activity_regulation
ACTIVITY REGULATION: Activated by calcium.
uniprot
proteins
amino_acid_sequence
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Dephosphorylates and destabilises PDCD5 to inhibit TP53/p53-mediated signaling (PubMed:28051100). May have a role in the recovery or adaptation response of photoreceptors (By similarity). {ECO:0000250|UniProtKB:P40421, ECO:0000269|PubMed:28051100}.
uniprot
proteins
mass_dalton
75792
uniprot
proteins
mutagenesis
MUTAGEN 172; /note="D->N: Abolishes activity."; /evidence="ECO:0000269|PubMed:28051100
uniprot
proteins
protein_family
PPP phosphatase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14759258
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
28051100
uniprot
proteins
pubmed
9215685
uniprot
proteins
pubmed
9326663
uniprot
proteins
pubmed
9430683
uniprot
proteins
sequence_length
653
uniprot
proteins