Kdsr
entrez
70750
canonical
uniprot
Q6GV12
canonical
ensembl
ENSMUSG00000009905
resolver
ensp
ENSMUSP00000010049
resolver
ensp
ENSMUSP00000274147
resolver
enst
ENSMUST00000010049
resolver
genesymbol
Kdsr
resolver
genesymbol_syn
Fvt1
resolver
uniprot
Q8CII3
resolver
uniprot_entry
KDSR_MOUSE
resolver
uniprot_entry
Q8CII3_MOUSE
resolver
amino_acid_sequence
MLLLAAAGLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKDIEKHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGTSMSGKFEELEVSSFEKLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEVKPYNVYVTVAYPPDTDTPGLAEENKTKPLETRLISETTAICKPEQVAKQIVKDAIQGNFNSSIGSDGYMLSSLTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDNIVRRCMVQKAKPEVVDKTA
uniprot
proteins
ec_number
1.1.1.102
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis. {ECO:0000269|PubMed:15328338}.
uniprot
proteins
mass_dalton
35956
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; sphingolipid metabolism.
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
15328338
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q06136}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 271..291; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 294..314; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins