Ppp1r14c
entrez
76142
canonical
uniprot
Q8R4S0
canonical
ensembl
ENSMUSG00000040653
resolver
ensp
ENSMUSP00000045110
resolver
ensp
ENSMUSP00000149688
resolver
ensp
ENSMUSP00000291775
resolver
enst
ENSMUST00000043374
resolver
enst
ENSMUST00000217573
resolver
genesymbol
Ppp1r14c
resolver
genesymbol_syn
Kepi
resolver
uniprot
A0A1L1SRZ2
resolver
uniprot_entry
A0A1L1SRZ2_MOUSE
resolver
uniprot_entry
PP14C_MOUSE
resolver
amino_acid_sequence
MSVVTGGGEAAGGGGGGGARVFFQSPRGGTGGSPGSSSSSGSSREDSAPVTTVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDANSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV
uniprot
proteins
function
FUNCTION: Inhibitor of the PP1 regulatory subunit PPP1CA. {ECO:0000269|PubMed:11812771}.
uniprot
proteins
mass_dalton
17754
uniprot
proteins
post_translational_modification
PTM: The main inhibitory site appears to be Thr-72 (By similarity). Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. {ECO:0000250, ECO:0000269|PubMed:11812771}.
uniprot
proteins
protein_family
PP1 inhibitor family
uniprot
proteins
pubmed
11812771
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
164
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endomembrane system {ECO:0000269|PubMed:11812771}; Peripheral membrane protein {ECO:0000269|PubMed:11812771}.
uniprot
proteins