Tomm5
entrez
68512
canonical
uniprot
B1AXP6
canonical
ensembl
ENSMUSG00000078713
resolver
ensp
ENSMUSP00000103438
resolver
ensp
ENSMUSP00000103440
resolver
genesymbol
Tomm5
resolver
genesymbol_syn
Tom5
resolver
uniprot
B1AXP7
resolver
uniprot
B1AXP8
resolver
uniprot
B1AXP9
resolver
uniprot_entry
TOM5_MOUSE
resolver
uniprot_sec
B1AXP7
resolver
uniprot_sec
B1AXP8
resolver
uniprot_sec
B1AXP9
resolver
amino_acid_sequence
MFRIEGLAPKLDPEEMKRKMREDVVSSIRNFLIYVALLRVTPYILKKLDSI
uniprot
proteins
function
FUNCTION: Component of the translocase of the outer membrane of mitochondria (TOM) complex essential for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (By similarity). The TOM complex associates with the ion channel VDAC2 and PINK1 kinase at depolarized mitochondria, this interaction stabilizes PINK1 at the outer mitochondrial membrane and triggers downstream mitophagy by the recruitment of the E3 ubiquitin ligase PRKN (By similarity). {ECO:0000250|UniProtKB:Q8N4H5}.
uniprot
proteins
mass_dalton
6037
uniprot
proteins
protein_family
Tom5 family
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
51
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8N4H5}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q8N4H5}.
uniprot
proteins
transmembrane_region
TRANSMEM 15..48; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q8N4H5
uniprot
proteins