RTRAF
entrez
68045
canonical
uniprot
Q9CQE8
canonical
ensembl
ENSMUSG00000021807
resolver
ensp
ENSMUSP00000022341
resolver
enst
ENSMUST00000022341
resolver
genesymbol
RTRAF
resolver
genesymbol
Rtraf
resolver
genesymbol_syn
2700060E02Rik
resolver
uniprot
Q4VA29
resolver
uniprot_entry
Q4VA29_MOUSE
resolver
uniprot_entry
RTRAF_MOUSE
resolver
amino_acid_sequence
MFRRKLTALDYHNPSGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFFEKYLKDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNRKNTDNAAKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALEKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR
uniprot
proteins
function
FUNCTION: Accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Could also play a role in RNA transport. {ECO:0000250|UniProtKB:Q9Y224}.
uniprot
proteins
mass_dalton
28152
uniprot
proteins
protein_family
RTRAF family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
244
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y224}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9Y224}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9Y224}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9Y224}. Note=May localize at the centrosome during mitosis. Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (By similarity). {ECO:0000250}.
uniprot
proteins