Bbc3
entrez
317673
canonical
uniprot
Q80ZG6
canonical
ensembl
ENSRNOG00000062473
resolver
ensembl
ENSRNOG00055016979
resolver
ensembl
ENSRNOG00060021083
resolver
ensembl
ENSRNOG00065033956
resolver
ensp
ENSRNOP00000092134
resolver
ensp
ENSRNOP00055023228
resolver
ensp
ENSRNOP00060030065
resolver
ensp
ENSRNOP00065047997
resolver
enst
ENSRNOT00000096062
resolver
enst
ENSRNOT00055028859
resolver
enst
ENSRNOT00060036532
resolver
enst
ENSRNOT00065058321
resolver
genesymbol
Bbc3
resolver
genesymbol_syn
Puma
resolver
uniprot
A0A8I6AHA0
resolver
uniprot_entry
A0A8I6AHA0_RAT
resolver
uniprot_entry
BBC3_RAT
resolver
amino_acid_sequence
MARARQEGSSPEPVEGLARDSPRPFPLGRLMPSAVSCGLCEPGLPAAPAAPALLPAAYLCAPTAPPAVTAALGGPRWPGGHRSRPRGPRPDGPQPSLSPAQQHLESPVPSAPEALAGGPTQAAPGVRVEEEEWAREIGAQLRRMADDLNAQYERRRQEEQHRHRPSPWRVMYNLFMGLLPLPRDPGAPEMEPN
uniprot
proteins
function
FUNCTION: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis. Regulates ER stress-induced neuronal apoptosis. {ECO:0000250|UniProtKB:Q99ML1, ECO:0000250|UniProtKB:Q9BXH1}.
uniprot
proteins
mass_dalton
20718
uniprot
proteins
protein_family
Bcl-2 family
uniprot
proteins
pubmed
12787069
uniprot
proteins
pubmed
17998337
uniprot
proteins
sequence_length
193
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release. {ECO:0000250}.
uniprot
proteins