CSTPP1
entrez
79096
canonical
uniprot
Q9H6J7
canonical
ensembl
ENSG00000149179
resolver
ensp
ENSP00000278460
resolver
ensp
ENSP00000367878
resolver
ensp
ENSP00000367881
resolver
ensp
ENSP00000378844
resolver
genesymbol
CSTPP1
resolver
genesymbol_syn
C11orf49
resolver
hgnc
HGNC:28720
resolver
uniprot
B4DUV7
resolver
uniprot
D3DQQ8
resolver
uniprot
E9PAX7
resolver
uniprot
Q7L077
resolver
uniprot
Q96CS8
resolver
uniprot
Q9BQH4
resolver
uniprot
Q9BUW5
resolver
uniprot_entry
B4DUV7_HUMAN
resolver
uniprot_entry
CSTP1_HUMAN
resolver
uniprot_sec
D3DQQ8
resolver
uniprot_sec
E9PAX7
resolver
uniprot_sec
Q7L077
resolver
uniprot_sec
Q96CS8
resolver
uniprot_sec
Q9BQH4
resolver
uniprot_sec
Q9BUW5
resolver
amino_acid_sequence
MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTEYFNSVCQGTHILFREFSFVQATPHNRVSFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYEDLLSGKNPNTVIVPTSSSGQHRQRPALGGAGTLEGVEASLFYQCLENLCDRHKYSCPPPALVKEALSNVQRLTFYGFLMALSKHRGINQALGALPDKGDLMHDPAMDEELERLLAQVPGLVNSVTASPEASCLPSRTPPRVGSPWRPLHHSRKVDGESDGSTEETDESET
uniprot
proteins
function
FUNCTION: Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly (PubMed:34782749). Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding (PubMed:34782749). {ECO:0000269|PubMed:34782749}.
uniprot
proteins
mass_dalton
37353
uniprot
proteins
protein_family
CSTPP1 family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
34782749
uniprot
proteins
pubmed
8889548
uniprot
proteins
sequence_length
331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:34782749}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:34782749}. Note=Associated with microtubules. {ECO:0000269|PubMed:34782749}.
uniprot
proteins