Efcab7
entrez
230500
canonical
uniprot
Q8VDY4
canonical
ensembl
ENSMUSG00000073791
resolver
ensp
ENSMUSP00000118989
resolver
ensp
ENSMUSP00000159398
resolver
ensp
ENSMUSP00000267100
resolver
enst
ENSMUST00000136874
resolver
enst
ENSMUST00000239516
resolver
genesymbol
Efcab7
resolver
genesymbol_syn
BC020077
resolver
genesymbol_syn
Kiaa1799
resolver
uniprot
Q2M1K0
resolver
uniprot
Q3UQS0
resolver
uniprot
Q5DTU8
resolver
uniprot_entry
EFCB7_MOUSE
resolver
uniprot_entry
Q2M1K0_MOUSE
resolver
uniprot_sec
Q3UQS0
resolver
uniprot_sec
Q5DTU8
resolver
amino_acid_sequence
MASNPGSDAALGTQNPLLSGSPRTKKFPLTEQEVFYMNCRAAYLTIFKSSLENIISKDQLYLALQHAGRNPSQKTINKYWTPQTAKLNFDDFCIILSKEKPTSKAELLKSFKKLDVNDDGAILHSDLQKYLTKRGEKMTQEEVNAVINLADINANGKFDYVKFCKLYMTTSEQCLKTTLERLEADSKLRRQQFGSHMEGSPERGPSPAPKPSPRVIRKNDQETFSSKGDTSHALLSTTRKFKTSVSFTMTMSANSNQDSTLTEPNLKDWQCAQSKGCFFLEEDGEVVSHQYKMHIAQRSVLYLTIKPLYLSQVEGKRCPWLSVDTALYILKKNENPAEPQLMCFTELRNREVFGWTGELEAGIYWLIPSTTGCRLKKETKPVTEEAQLVHRDETGELSLTSEFRSTLSEIFEVIDLDGNGLISLEEYNFFELRTSGEKCDEDAWAVCRENFDTKKNELTRQGFMDLHLMEANDREGDPLDLWVTLHSMGYNKALELTEACPFVINIYAERCKPRIKVVHMEACSGQLEKAICKSVLDRSDAKVMDGYENIIVHTCNYDTWITSIIENKSDNKVIIHINNELSKNCVNNRGLNIFAVEVAPRSTMVCQHVMPLNEQEEWIYCCVYSLVA
uniprot
proteins
function
FUNCTION: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (PubMed:24582806). Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia (PubMed:24582806). {ECO:0000269|PubMed:24582806}.
uniprot
proteins
mass_dalton
71442
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
24582806
uniprot
proteins
sequence_length
628
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium membrane {ECO:0000269|PubMed:24582806}; Peripheral membrane protein {ECO:0000269|PubMed:24582806}; Cytoplasmic side {ECO:0000269|PubMed:24582806}. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner (PubMed:24582806). {ECO:0000269|PubMed:24582806}.
uniprot
proteins