Itgad
entrez
64350
canonical
uniprot
Q9QYE7
canonical
ensembl
ENSRNOG00000068399
resolver
ensp
ENSRNOP00000071107
resolver
genesymbol
Itgad
resolver
genesymbol_syn
Itgax
resolver
uniprot_entry
ITAD_RAT
resolver
amino_acid_sequence
MAGGVVILLCGWVLASCHGSNLDVEEPIVFREDAASFGQTVVQFGGSRLVVGAPLEAVAVNQTGRLYDCAPATGMCQPIVLRSPLEAVNMSLGLSLVTATNNAQLLACGPTAQRACVKNMYAKGSCLLLGSSLQFIQAVPASMPECPRQEMDIAFLIDGSGSINQRDFAQMKDFVKALMGEFASTSTLFSLMQYSNILKTHFTFTEFKNILDPQSLVDPIVQLQGLTYTATGIRTVMEELFHSKNGSRKSAKKILLVITDGQKYRDPLEYSDVIPAADKAGIIRYAIGVGDAFQEPTALKELNTIGSAPPQDHVFKVGNFAALRSIQRQLQEKIFAIEGTQSRSSSSFQHEMSQEGFSSALTSDGPVLGAVGSFSWSGGAFLYPPNTRPTFINMSQENVDMRDSYLGYSTAVAFWKGVHSLILGAPRHQHTGKVVIFTQEARHWRPKSEVRGTQIGSYFGASLCSVDVDRDGSTDLVLIGAPHYYEQTRGGQVSVFPVPGVRGRWQCEATLHGEQGHPWGRFGVALTVLGDVNGDNLADVAIGAPGEEESRGAVYIFHGASRLEIMPSPSQRVTGSQLSLRLQYFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVELSIRFAPMEVAKAVYQCWERTPTVLEAGEATVCLTVHKGSPDLLGNVQGSVRYDLALDPGRLISRAIFDETKNCTLTGRKTLGLGDHCETVKLLLPDCVEDAVSPIILRLNFSLVRDSASPRNLHPVLAVGSQDHITASLPFEKNCKQELLCEGDLGISFNFSGLQVLVVGGSPELTVTVTVWNEGEDSYGTLVKFYYPAGLSYRRVTGTQQPHQYPLRLACEAEPAAQEDLRSSSCSINHPIFREGAKTTFMITFDVSYKAFLGDRLLLRAKASSENNKPDTNKTAFQLELPVKYTVYTLISRQEDSTNHVNFSSSHGGRRQEAAHRYRVNNLSPLKLAVRVNFWVPVLLNGVAVWDVTLSSPAQGVSCVSQMKPPQNPDFLTQIQRRSVLDCSIADCLHFRCDIPSLDIQDELDFILRGNLSFGWVSQTLQEKVLLVSEAEITFDTSVYSQLPGQEAFLRAQVETTLEEYVVYEPIFLVAGSSVGGLLLLALITVVLYKLGFFKRQYKEMLDGKAADPVTAGQADFGCETPPYLVS
uniprot
proteins
function
FUNCTION: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood. {ECO:0000250|UniProtKB:Q13349}.
uniprot
proteins
mass_dalton
126600
uniprot
proteins
protein_family
Integrin alpha chain family
uniprot
proteins
sequence_length
1161
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q13349}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 1101..1121; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins