Kif2b
entrez
73470
canonical
uniprot
Q8C0N1
canonical
ensembl
ENSMUSG00000046755
resolver
ensp
ENSMUSP00000058084
resolver
enst
ENSMUST00000061019
resolver
genesymbol
Kif2b
resolver
uniprot
A2RSC8
resolver
uniprot_entry
A2RSC8_MOUSE
resolver
uniprot_entry
KIF2B_MOUSE
resolver
amino_acid_sequence
MASQFCLPLAPRLSPLKPLKSHFTDFQVGICVAIQRSDKRIHLAVVTEINRENSWVTVEWVEKGVKKGKKIELETVLLLNPALASLEHQRSRRPLRPVSVVPSTAIGDQRTATKWIAMIPHRNETPSGDSQTLMIPSNPCLMKRKKSPCLREIEKLQKQREKRRRLQLEIRARRALDINTGNPNFETMRMIEEYRRRLDSSKMSSLEPPEDHRICVCVRKRPLNQRETTMKDLDIITIPSHNVVMVHESKQKVDLTRYLENQTFCFDHAFDDKASNELVYQFTARPLVESIFRKGMATCFAYGQTGSGKTHTMGGAFLGKAQDCSKGIYALVAQDVFLLLKTPAYEKLELKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGNQQVQVVGLQEQEVSCVEEVLNLVELGNSCRTSGQTSVNAHSSRSHAVFQLILKAGGKLHGKFSLVDLAGNERGADTAKATRKRQLEGAEINKSLLALKECIRALGKNKSHTPFRASKLTQVLRDSFIGQNSYTCMIATISPGMTSCENTLNTLRYANRVKELALEARPYHHCVSPPGHEVPLMIENDNTNSGKSLQRDEVIQIPTVEKEEEKESDELTSKKEPAASWSRSNQWWEAIQETAEGVNGDVDFCIAQSLSVLEQKIGVLTDIQKKLQSLREDLQKKSQVE
uniprot
proteins
function
FUNCTION: Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement during mitosis. Has microtubule depolymerization activity. Plays a role in chromosome congression. {ECO:0000250|UniProtKB:Q8N4N8}.
uniprot
proteins
mass_dalton
75469
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Thr-125 by PLK1 is required for activity in the correction of kinetochore-microtubules attachment errors, while phosphorylation at Ser-204 also by PLK1 is required for the kinetochore localization and activity in prometaphase. {ECO:0000250|UniProtKB:Q8N4N8}.
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
MCAK/KIF2 subfamily
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
668
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q8N4N8}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q8N4N8}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:Q8N4N8}. Note=Association with kinetochore is transient. {ECO:0000250|UniProtKB:Q8N4N8}.
uniprot
proteins