Id1
entrez
25261
canonical
uniprot
P41135
canonical
ensembl
ENSRNOG00000021750
resolver
ensp
ENSRNOP00000052261
resolver
enst
ENSRNOT00000029660
resolver
genesymbol
Id1
resolver
genesymbol_syn
Id-1
resolver
uniprot
A0A8L2QPI3
resolver
uniprot
A0JPJ2
resolver
uniprot_entry
A0A8L2QPI3_RAT
resolver
uniprot_entry
A0JPJ2_RAT
resolver
uniprot_entry
ID1_RAT
resolver
amino_acid_sequence
MKVASSSAAATAGPSCSLKAGRTAGEVVLGLSEQSVAISRCAGTRLPALLDEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVATAGGRGLPVRAPLSTLNGEISALAAEVRSESEYYIILLWETKATGGGCPPYFSGA
uniprot
proteins
function
FUNCTION: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
17397
uniprot
proteins
post_translational_modification
PTM: Phosphorylated in vitro by PKA and PKC. {ECO:0000269|PubMed:7864897}.
uniprot
proteins
pubmed
1378442
uniprot
proteins
pubmed
7864897
uniprot
proteins
pubmed
7908517
uniprot
proteins
pubmed
8106493
uniprot
proteins
sequence_length
164
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus.
uniprot
proteins