Slc7a13
entrez
313089
canonical
uniprot
Q5RKI7
canonical
ensembl
ENSRNOG00000024903
resolver
ensp
ENSRNOP00000032751
resolver
enst
ENSRNOT00000035685
resolver
genesymbol
Slc7a13
resolver
uniprot_entry
S7A13_RAT
resolver
amino_acid_sequence
MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES
uniprot
proteins
function
FUNCTION: Associates with SLC3A1/rBAT to form a functional heterodimeric complex that transports anionic and neutral amino acids across the apical plasma membrane of renal epithelium. Preferentially mediates exchange transport, but can also operate via facilitated diffusion. May act as a major transporter for L-cystine in late proximal tubules, ensuring its reabsorption from the luminal fluid in exchange for cytosolic L-glutamate or L-aspartate. {ECO:0000250|UniProtKB:Q91WN3}.
uniprot
proteins
mass_dalton
53551
uniprot
proteins
protein_family
Amino acid-polyamine-organocation (APC) superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
479
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:Q91WN3}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 15..35; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 48..68; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 90..110; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 130..150; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 166..186; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 243..263; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 290..310; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 339..359; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 361..381; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 397..417; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 424..444; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins