CDK5R2
entrez
8941
canonical
uniprot
Q13319
canonical
ensembl
ENSG00000171450
resolver
ensp
ENSP00000304250
resolver
enst
ENST00000302625
resolver
genesymbol
CDK5R2
resolver
genesymbol_syn
NCK5AI
resolver
hgnc
HGNC:1776
resolver
uniprot
Q4ZFW6
resolver
uniprot_entry
CD5R2_HUMAN
resolver
uniprot_sec
Q4ZFW6
resolver
amino_acid_sequence
MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVYLLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRLIQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKHWTMNLDR
uniprot
proteins
function
FUNCTION: Activator of CDK5/TPKII.
uniprot
proteins
mass_dalton
38705
uniprot
proteins
mutagenesis
MUTAGEN 2; /note="G->A: Absent from the cell periphery."; /evidence="ECO:0000269|PubMed:18507738
uniprot
proteins
post_translational_modification
PTM: Myristoylated. The Gly-2-Ala mutant is absent of the cell periphery, suggesting that a proper myristoylation signal is essential for the proper distribution of CDK5R2 (p39). {ECO:0000269|PubMed:18507738}.
uniprot
proteins
protein_family
Cyclin-dependent kinase 5 activator family
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
18507738
uniprot
proteins
pubmed
7592934
uniprot
proteins
sequence_length
367
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:18507738}; Lipid-anchor {ECO:0000269|PubMed:18507738}; Cytoplasmic side {ECO:0000269|PubMed:18507738}.
uniprot
proteins