Bzw2
entrez
171439
canonical
uniprot
Q9WTT7
canonical
ensembl
ENSRNOG00000005096
resolver
ensembl
ENSRNOG00055019516
resolver
ensembl
ENSRNOG00060005691
resolver
ensembl
ENSRNOG00065009497
resolver
ensp
ENSRNOP00000007414
resolver
ensp
ENSRNOP00055027024
resolver
ensp
ENSRNOP00060007125
resolver
ensp
ENSRNOP00065011398
resolver
enst
ENSRNOT00000007414
resolver
enst
ENSRNOT00055033313
resolver
enst
ENSRNOT00060009474
resolver
enst
ENSRNOT00065015196
resolver
genesymbol
Bzw2
resolver
genesymbol_syn
5mp1
resolver
genesymbol_syn
Bdm2
resolver
genesymbol_syn
Hfb2
resolver
uniprot_entry
5MP1_RAT
resolver
amino_acid_sequence
MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSEAEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELVLLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHAAKGKSVFLDQMKKFVEWLQNAEEESESEGEES
uniprot
proteins
function
FUNCTION: Translation initiation regulator which represses non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (By similarity). Increases the accuracy of translation initiation by impeding EIF5-dependent translation from non-AUG codons by competing with it for interaction with EIF2S2 within the 43S pre-initiation complex (PIC) in an EIF3C-binding dependent manner (By similarity). {ECO:0000250|UniProtKB:Q9Y6E2}.
uniprot
proteins
mass_dalton
48049
uniprot
proteins
protein_family
BZW family
uniprot
proteins
pubmed
10727730
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
419
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Y6E2}.
uniprot
proteins