Aftph
entrez
216549
canonical
uniprot
Q80WT5
canonical
ensembl
ENSMUSG00000049659
resolver
ensp
ENSMUSP00000036778
resolver
ensp
ENSMUSP00000121612
resolver
ensp
ENSMUSP00000134991
resolver
ensp
ENSMUSP00000162389
resolver
enst
ENSMUST00000177543
resolver
genesymbol
Aftph
resolver
genesymbol_syn
Afth
resolver
uniprot
H3BJH7
resolver
uniprot
Q5SSE6
resolver
uniprot
Q99KJ1
resolver
uniprot_entry
AFTIN_MOUSE
resolver
uniprot_entry
H3BJH7_MOUSE
resolver
uniprot_sec
Q5SSE6
resolver
uniprot_sec
Q99KJ1
resolver
amino_acid_sequence
MEPDIIRMYSSSPPPLDNGAEDDEEDEFGEFGGFSEVSPSGVGFVDFDTPDYTRPKEDFVPSNHFMPIHEYSEDVDSLTSFKSVQNGNDKDITAELSTPVKSQSDVVLSTTSKEMIPSKTLDPSIDGMESLEDLDKVVVQGPSTGQLRSFSPGDFRTDKNIVHQTKQLESCNGEKPPCLEILTNGFAGLETVNPQGTDDLDNVADSKGSKPLNTCGTECILESAASHATEFADFSTFSQTERTQLEEIECPVLNDGDTLTIQGNSKGPRVKELNCVKEVTLDGSFEDTGNTEREHQVCVSEIHAVADRGLSVEKQDLQTLQQDEFLNSRIQSEAWSLVDSSENSEAITKERCKMEKNDLFASKCADLSMDSVKTSDVNEIGSSKEENRKLTNPKSPDPDPTGQNALDDSAASMKNGDSGNGFVTCHDTNEDDFGDFGTANGTTPPFVTSTQDSMSDVTFEDSSEHFLHLSEPGDDFGEFEDTNAVSCQEEMRFTESDLRQTSDGLSEECPLAGESGGKDSKPDSKLKNGQDSEFGDFDSVPNTQGSAFQDSDDFADFSSAGPSQAVDWNAFEDEQKDGCSWAAFGDQQETESHHLKEVWQSQRTDETMGTLGTPKMHSVSSAASKGAVASGHLQEPGTSVQTALLNRLERIFEACFPSVFVPDVEEEVSSLKHLLETHSSPAKTREALADRGELRGVWTELQDIHDAHGLRYQWGGSHSNKKLLCSLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEPTKEPLKPLSAAEKIASIGQTTVMTPEINTCTSDPFQESLPPVQFDWSSSGLTNPLDASGGSTLLNLDFFGPVDDSSSSSSTIPGVDPELYELTTAKLETSTSSLRVTDAFAKLMSTVEKTSTSTRKPKREEHLSEEAMKVIASLPDLTFMHAKVLMFPATLTPSMSSQEQADA
uniprot
proteins
function
FUNCTION: Component of clathrin-coated vesicles (By similarity). Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (By similarity). {ECO:0000250|UniProtKB:Q6ULP2}.
uniprot
proteins
mass_dalton
101131
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
931
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6ULP2}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q6ULP2}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250|UniProtKB:Q6ULP2}. Note=Co-localizes with AP1G1/AP-1 in the cytoplasm (By similarity). Recruited to the perinuclear region by AP1G1/AP-1 (By similarity). {ECO:0000250|UniProtKB:Q6ULP2}.
uniprot
proteins