Dad1
entrez
192275
canonical
uniprot
P61805
canonical
ensembl
ENSRNOG00000009090
resolver
ensembl
ENSRNOG00055012038
resolver
ensembl
ENSRNOG00060025638
resolver
ensembl
ENSRNOG00065033446
resolver
ensp
ENSRNOP00000012233
resolver
ensp
ENSRNOP00000092852
resolver
ensp
ENSRNOP00055016463
resolver
ensp
ENSRNOP00060036789
resolver
ensp
ENSRNOP00065047345
resolver
enst
ENSRNOT00000012233
resolver
enst
ENSRNOT00000098684
resolver
enst
ENSRNOT00055020459
resolver
enst
ENSRNOT00060044393
resolver
enst
ENSRNOT00065057504
resolver
genesymbol
Dad1
resolver
uniprot
A0A8L2Q6I7
resolver
uniprot
O08552
resolver
uniprot
O70364
resolver
uniprot
P46966
resolver
uniprot
P46968
resolver
uniprot
Q96GB7
resolver
uniprot_entry
A0A8L2Q6I7_RAT
resolver
uniprot_entry
DAD1_RAT
resolver
uniprot_sec
O08552
resolver
uniprot_sec
O70364
resolver
uniprot_sec
P46966
resolver
uniprot_sec
P46968
resolver
uniprot_sec
Q96GB7
resolver
amino_acid_sequence
MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
uniprot
proteins
function
FUNCTION: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. {ECO:0000250|UniProtKB:E2R4X3, ECO:0000250|UniProtKB:P61803}.
uniprot
proteins
mass_dalton
12497
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:P61803}.
uniprot
proteins
protein_family
DAD/OST2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
113
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 31..51; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 93..113; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins