GIMAP7
entrez
168537
canonical
uniprot
Q8NHV1
canonical
ensembl
ENSG00000179144
resolver
ensp
ENSP00000315474
resolver
ensp
ENSP00000625252
resolver
ensp
ENSP00000625253
resolver
enst
ENST00000313543
resolver
enst
ENST00000955193
resolver
enst
ENST00000955194
resolver
genesymbol
GIMAP7
resolver
genesymbol_syn
IAN7
resolver
hgnc
HGNC:22404
resolver
uniprot_entry
GIMA7_HUMAN
resolver
amino_acid_sequence
MAESEDRSLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGRDLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLLLGRYTEEEQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEERLKQREEVLRKIYTDQLNEEIKLVEEDKHKSEEEKEKEIKLLKLKYDEKIKNIREEAERNIFKDVFNRIWKMLSEIWHRFLSKCKFYSS
uniprot
proteins
function
FUNCTION: The dimer has GTPase activity; the active site contains residues from both subunits. {ECO:0000269|PubMed:23454188}.
uniprot
proteins
mass_dalton
34509
uniprot
proteins
mutagenesis
MUTAGEN 103; /note="R->D: Abolishes GTPase activity. No effect on GTP binding and on dimerization."; /evidence="ECO:0000269|PubMed:23454188"; MUTAGEN 136; /note="E->W: Impairs dimerization and abolishes GTPase activity. No effect on GTP binding."; /evidence="ECO:0000269|PubMed:23454188
uniprot
proteins
protein_family
AIG1/Toc34/Toc159-like paraseptin GTPase family
uniprot
proteins
protein_family
IAN subfamily
uniprot
proteins
protein_family
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
uniprot
proteins
pubmed
15474311
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23454188
uniprot
proteins
sequence_length
300
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lipid droplet {ECO:0000269|PubMed:23454188}. Cytoplasm {ECO:0000269|PubMed:23454188}. Endoplasmic reticulum {ECO:0000269|PubMed:15474311}. Golgi apparatus {ECO:0000269|PubMed:15474311}. Note=Colocalizes with GIMAP2 on the surface of cytoplasmic lipid droplets.
uniprot
proteins