DMBX1
entrez
127343
canonical
uniprot
Q8NFW5
canonical
ensembl
ENSG00000197587
resolver
ensp
ENSP00000353132
resolver
ensp
ENSP00000598413
resolver
genesymbol
DMBX1
resolver
genesymbol_syn
MBX
resolver
genesymbol_syn
OTX3
resolver
genesymbol_syn
PAXB
resolver
hgnc
HGNC:19026
resolver
uniprot
A6NNN2
resolver
uniprot
Q8NFW6
resolver
uniprot
Q8NHD9
resolver
uniprot_entry
DMBX1_HUMAN
resolver
uniprot_sec
A6NNN2
resolver
uniprot_sec
Q8NFW6
resolver
uniprot_sec
Q8NHD9
resolver
amino_acid_sequence
MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLRLRAKQHAASLGLDTLPN
uniprot
proteins
function
FUNCTION: Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
41198
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
12055180
uniprot
proteins
pubmed
12142024
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
30237576
uniprot
proteins
sequence_length
382
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O35137, ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}.
uniprot
proteins