Malsu1
entrez
75593
canonical
uniprot
Q9CWV0
canonical
ensembl
ENSMUSG00000029815
resolver
ensp
ENSMUSP00000122941
resolver
ensp
ENSMUSP00000221966
resolver
ensp
ENSMUSP00000221971
resolver
enst
ENSMUST00000128616
resolver
genesymbol
Malsu1
resolver
uniprot_entry
MASU1_MOUSE
resolver
amino_acid_sequence
MGPGWSPARRLWPLLWRRAVFQRAGPAMASVPWLPRLAERWLPARPATCLTPSLTRGLHHGPQPEERTAGDARLQPGPADHIGAKFDIDMLVSLLRQENARDICVIQVPPEMRYTDYFVIGSGTSTRHLHAMVHYLVKMYKHLKCRSDPYVKIEGKDADDWLCVDFGSMVIHLMLPETRETYELEKLWTLRSFDDQLAQIAAETLPEDFILGLEDDTSSLTPVEFKCK
uniprot
proteins
function
FUNCTION: Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits. Interacts with mitochondrial ribosomal protein uL14m (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. May function as a ribosomal silencing factor. {ECO:0000250|UniProtKB:Q96EH3}.
uniprot
proteins
mass_dalton
26020
uniprot
proteins
protein_family
Iojap/RsfS family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
228
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q96EH3}. Note=Colocalizes with MRPL12 and/or MRPL14. {ECO:0000250|UniProtKB:Q96EH3}.
uniprot
proteins