CLEC2D
entrez
29121
canonical
uniprot
Q9UHP7
canonical
ensembl
ENSG00000069493
resolver
ensp
ENSP00000261339
resolver
ensp
ENSP00000261340
resolver
ensp
ENSP00000290855
resolver
ensp
ENSP00000443065
resolver
ensp
ENSP00000444818
resolver
genesymbol
CLEC2D
resolver
genesymbol_syn
CLAX
resolver
genesymbol_syn
LLT1
resolver
genesymbol_syn
OCIL
resolver
hgnc
HGNC:14351
resolver
uniprot
D6CI39
resolver
uniprot
D6CI40
resolver
uniprot
D6CI41
resolver
uniprot
Q6YID5
resolver
uniprot
Q8WUP7
resolver
uniprot
Q9HD37
resolver
uniprot
Q9HD38
resolver
uniprot
W8JXM2
resolver
uniprot_entry
CLC2D_HUMAN
resolver
uniprot_entry
W8JXM2_HUMAN
resolver
uniprot_sec
D6CI39
resolver
uniprot_sec
D6CI40
resolver
uniprot_sec
D6CI41
resolver
uniprot_sec
Q6YID5
resolver
uniprot_sec
Q8WUP7
resolver
uniprot_sec
Q9HD37
resolver
uniprot_sec
Q9HD38
resolver
amino_acid_sequence
MHDSNNVEKDITPSELPANPGCLHSKEHSIKATLIWRLFFLIMFLTIIVCGMVAALSAIRANCHQEPSVCLQAACPESWIGFQRKCFYFSDDTKNWTSSQRFCDSQDADLAQVESFQELNFLLRYKGPSDHWIGLSREQGQPWKWINGTEWTRQFPILGAGECAYLNDKGASSARHYTERKWICSKSDIHV
uniprot
proteins
function
FUNCTION: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:16339513, PubMed:20843815). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone resorption (PubMed:14753741). Modulates the release of interferon-gamma (PubMed:15104121). Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656). {ECO:0000269|PubMed:14753741, ECO:0000269|PubMed:15104121, ECO:0000269|PubMed:15123656, ECO:0000269|PubMed:16339513, ECO:0000269|PubMed:20843815}.
uniprot
proteins
mass_dalton
21849
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:15104121, ECO:0000269|PubMed:20843815, ECO:0000269|PubMed:25760607}.
uniprot
proteins
pubmed
10541800
uniprot
proteins
pubmed
14753741
uniprot
proteins
pubmed
15104121
uniprot
proteins
pubmed
15123656
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16339513
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
20843815
uniprot
proteins
pubmed
25760607
uniprot
proteins
pubmed
25826155
uniprot
proteins
sequence_length
191
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15104121, ECO:0000269|PubMed:20843815, ECO:0000305|PubMed:16339513}; Single-pass type II membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum {ECO:0000269|PubMed:20843815}.; SUBCELLULAR LOCATION: [Isoform 4]: Endoplasmic reticulum {ECO:0000269|PubMed:20843815}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins