Nefl
entrez
83613
canonical
uniprot
P19527
canonical
ensembl
ENSRNOG00000013658
resolver
ensembl
ENSRNOG00055006877
resolver
ensembl
ENSRNOG00060010521
resolver
ensembl
ENSRNOG00065018809
resolver
ensp
ENSRNOP00000018599
resolver
ensp
ENSRNOP00055008886
resolver
ensp
ENSRNOP00060013824
resolver
ensp
ENSRNOP00065025187
resolver
enst
ENSRNOT00055011317
resolver
enst
ENSRNOT00060017783
resolver
enst
ENSRNOT00065031593
resolver
genesymbol
Nefl
resolver
genesymbol_syn
Nf68
resolver
genesymbol_syn
Nfl
resolver
uniprot
Q63367
resolver
uniprot_entry
NFL_RAT
resolver
uniprot_sec
Q63367
resolver
amino_acid_sequence
MSSFSYEPYFSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEIAFLKKVHEEEIAELQAQIQYAQISVEMDVSSKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRSTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYSGLQSSSYLMSARAFPAYYTSHVQEEQSEVEETIEATKAEEAKDEPPSEGEAEEEEKEKEEGEEEEGAEEEEAAKDESEDAKEEEGGEGEEEDTKESEEEEKKEESAGEEQAAKKKD
uniprot
proteins
function
FUNCTION: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). {ECO:0000250|UniProtKB:P08551}.
uniprot
proteins
mass_dalton
61335
uniprot
proteins
post_translational_modification
PTM: O-glycosylated; contains three N-acetylglucosamine side chains. {ECO:0000269|PubMed:8344946}.; PTM: Phosphorylated in the head and rod regions by the PKC kinase PKN1, leading to the inhibition of polymerization. {ECO:0000250}.; PTM: Ubiquitinated in the presence of TRIM2 and UBE2D1. {ECO:0000250}.
uniprot
proteins
protein_family
Intermediate filament family
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2516804
uniprot
proteins
pubmed
3925999
uniprot
proteins
pubmed
7745611
uniprot
proteins
pubmed
8344946
uniprot
proteins
pubmed
9388258
uniprot
proteins
sequence_length
542
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000250|UniProtKB:P08551}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P08551}.
uniprot
proteins