Hepacam
entrez
72927
canonical
uniprot
Q640R3
canonical
ensembl
ENSMUSG00000046240
resolver
ensp
ENSMUSP00000054105
resolver
enst
ENSMUST00000051839
resolver
genesymbol
Hepacam
resolver
uniprot
B2RSY3
resolver
uniprot_entry
B2RSY3_MOUSE
resolver
uniprot_entry
HECAM_MOUSE
resolver
amino_acid_sequence
MKRERGALSRASRALRLSPFVYLLLIQPVPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDKPVVKWQLKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKPSYTWLKDGKPLLNDSRMLLSPDQKVLTITRVLMEDDDLYSCVVENPISQVRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCACWKPSKKSRKKRKLEKQNSLEYMDQNDDRLKSEADTLPRSGEQERKNPMALYILKDKDSSEPDENPATEPRSTTEPGPPGYSVSPPVPGRSPGLPIRSARRYPRSPARSPATGRTHTSPPRAPSSPGRSRSSSRSLRTAGVQRIREQDESGQVEISA
uniprot
proteins
function
FUNCTION: Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation (By similarity). In glia, associates and targets CLCN2 at astrocytic processes and myelinated fiber tracts where it may regulate transcellular chloride flux involved in neuron excitability. {ECO:0000250|UniProtKB:Q14CZ8, ECO:0000269|PubMed:22405205}.
uniprot
proteins
mass_dalton
46367
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q14CZ8}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17114649
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22405205
uniprot
proteins
sequence_length
418
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cell membrane {ECO:0000269|PubMed:22405205}; Single-pass type I membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250|UniProtKB:Q14CZ8}. Note=Colocalizes with CDH1 (By similarity). Colocalizes with CLCN2 at astrocyte end-foot in contact with brain capillaries and other glial cells (PubMed:22405205). {ECO:0000250|UniProtKB:Q14CZ8, ECO:0000269|PubMed:22405205}.
uniprot
proteins
transmembrane_region
TRANSMEM 241..261; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins