EEF1E1
entrez
9521
canonical
uniprot
O43324
canonical
ensembl
ENSG00000124802
resolver
ensp
ENSP00000369038
resolver
ensp
ENSP00000414363
resolver
genesymbol
EEF1E1
resolver
genesymbol_syn
AIMP3
resolver
genesymbol_syn
P18
resolver
hgnc
HGNC:3212
resolver
uniprot
C9JLK5
resolver
uniprot
Q5THS2
resolver
uniprot_entry
MCA3_HUMAN
resolver
uniprot_sec
C9JLK5
resolver
uniprot_sec
Q5THS2
resolver
amino_acid_sequence
MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSVVFIKNRLYTNSH
uniprot
proteins
function
FUNCTION: Positive modulator of ATM response to DNA damage. {ECO:0000250|UniProtKB:Q9D1M4}.
uniprot
proteins
mass_dalton
19811
uniprot
proteins
mutagenesis
MUTAGEN 69; /note="A->R: Disrupts interaction with MARS1."; /evidence="ECO:0000269|PubMed:26472928"; MUTAGEN 73; /note="Q->R: Disrupts interaction with MARS1."; /evidence="ECO:0000269|PubMed:26472928"; MUTAGEN 144; /note="R->A: Disrupts interaction with EPRS1."; /evidence="ECO:0000269|PubMed:26472928
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15680327
uniprot
proteins
pubmed
18343821
uniprot
proteins
pubmed
19131329
uniprot
proteins
pubmed
19289464
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
26472928
uniprot
proteins
pubmed
9653160
uniprot
proteins
sequence_length
174
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15680327}. Cytoplasm, cytosol {ECO:0000269|PubMed:19289464}. Nucleus {ECO:0000269|PubMed:15680327}. Note=Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage.
uniprot
proteins