Slc20a1
entrez
20515
canonical
uniprot
Q61609
canonical
ensembl
ENSMUSG00000027397
resolver
ensp
ENSMUSP00000028880
resolver
ensp
ENSMUSP00000105944
resolver
ensp
ENSMUSP00000203620
resolver
enst
ENSMUST00000028880
resolver
enst
ENSMUST00000110315
resolver
genesymbol
Slc20a1
resolver
genesymbol_syn
Glvr1
resolver
genesymbol_syn
Pit1
resolver
uniprot
A2AKR9
resolver
uniprot
Q3U244
resolver
uniprot
Q8CBJ1
resolver
uniprot
Q91YQ9
resolver
uniprot
Q9QVW6
resolver
uniprot_entry
S20A1_MOUSE
resolver
uniprot_sec
A2AKR9
resolver
uniprot_sec
Q3U244
resolver
uniprot_sec
Q8CBJ1
resolver
uniprot_sec
Q91YQ9
resolver
uniprot_sec
Q9QVW6
resolver
amino_acid_sequence
MESTVATITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRNGLIDVELYNETQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVANGQKGVKWSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKADPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKSSPSESPLMEKKSNLKEDHEETKMAPGDVEHRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLPMDLKEETSIDSTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMSVKAEMGLGDRKGSSGSLEEWYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYKQEASTKAATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKYIILPV
uniprot
proteins
function
FUNCTION: Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. Essential for cell proliferation but this function is independent of its phosphate transporter activity. {ECO:0000250|UniProtKB:Q8WUM9}.; FUNCTION: (Microbial infection) May function as a retroviral receptor but do not confer infection susceptibility to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B). {ECO:0000269|PubMed:12097582, ECO:0000269|PubMed:1309898}.
uniprot
proteins
mass_dalton
74153
uniprot
proteins
mutagenesis
MUTAGEN 553..560; /note="KQEASTKA->DTGDVSSKV: Confers virus infectibility."; /evidence="ECO:0000269|PubMed:8411375"; MUTAGEN 553..555; /note="KQE->DTGD: Confers virus infectibility."; /evidence="ECO:0000269|PubMed:8411375"; MUTAGEN 553; /note="K->DT: Confers virus infectibility."; /evidence="ECO:0000269|PubMed:8411375
uniprot
proteins
protein_family
Inorganic phosphate transporter (PiT) (TC 2.A.20) family
uniprot
proteins
pubmed
10689185
uniprot
proteins
pubmed
12097582
uniprot
proteins
pubmed
1309898
uniprot
proteins
pubmed
1531369
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8046392
uniprot
proteins
pubmed
8411375
uniprot
proteins
pubmed
9755124
uniprot
proteins
pubmed
9916777
uniprot
proteins
sequence_length
681
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8WUM9}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 66..86; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 162..182; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 234..254; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 514..534; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 561..581; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 602..622; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 652..672; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins