GNL3
entrez
26354
canonical
uniprot
Q9BVP2
canonical
ensembl
ENSG00000163938
resolver
ensp
ENSP00000378278
resolver
ensp
ENSP00000395772
resolver
genesymbol
GNL3
resolver
genesymbol_syn
E2IG3
resolver
genesymbol_syn
NS
resolver
hgnc
HGNC:29931
resolver
uniprot
B2RDC1
resolver
uniprot
Q5PU80
resolver
uniprot
Q96SV6
resolver
uniprot
Q96SV7
resolver
uniprot
Q9UJY0
resolver
uniprot_entry
GNL3_HUMAN
resolver
uniprot_sec
B2RDC1
resolver
uniprot_sec
Q5PU80
resolver
uniprot_sec
Q96SV6
resolver
uniprot_sec
Q96SV7
resolver
uniprot_sec
Q9UJY0
resolver
amino_acid_sequence
MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV
uniprot
proteins
function
FUNCTION: May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). {ECO:0000250, ECO:0000269|PubMed:12464630, ECO:0000269|PubMed:16012751}.
uniprot
proteins
mass_dalton
61993
uniprot
proteins
protein_family
TRAFAC class YlqF/YawG GTPase family
uniprot
proteins
pubmed
11085516
uniprot
proteins
pubmed
11790298
uniprot
proteins
pubmed
12429849
uniprot
proteins
pubmed
12464630
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16012751
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25114211
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
34681573
uniprot
proteins
sequence_length
549
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus {ECO:0000269|PubMed:11790298, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:12464630}. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}.
uniprot
proteins