Mpv17
entrez
360463
canonical
uniprot
Q5BK62
canonical
ensembl
ENSRNOG00000049430
resolver
ensp
ENSRNOP00000037647
resolver
ensp
ENSRNOP00000092589
resolver
enst
ENSRNOT00000102606
resolver
genesymbol
Mpv17
resolver
genesymbol_syn
Mpv17l
resolver
uniprot
A0A8I6ADY6
resolver
uniprot_entry
A0A8I6ADY6_RAT
resolver
uniprot_entry
MPV17_RAT
resolver
amino_acid_sequence
MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQQHQTGRTLTMASLGCGFVGPVVGGWYRVLDHLIPGTTKVNALKKMLLDQGGFAPCFLGCFLPLVGVLNGMSAQDNWAKLKRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVVWNSYLSWKAHQL
uniprot
proteins
function
FUNCTION: Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity). {ECO:0000250|UniProtKB:P19258, ECO:0000250|UniProtKB:P39210}.
uniprot
proteins
mass_dalton
19627
uniprot
proteins
protein_family
Peroxisomal membrane protein PXMP2/4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
176
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P39210}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P39210}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 57..77; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 94..114; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..151; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins