METAP1
entrez
23173
canonical
uniprot
P53582
canonical
ensembl
ENSG00000164024
resolver
ensp
ENSP00000296411
resolver
ensp
ENSP00000594404
resolver
enst
ENST00000296411
resolver
genesymbol
METAP1
resolver
genesymbol_syn
KIAA0094
resolver
hgnc
HGNC:15789
resolver
uniprot
B4E2E6
resolver
uniprot_entry
MAP11_HUMAN
resolver
uniprot_sec
B4E2E6
resolver
amino_acid_sequence
MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMSQF
uniprot
proteins
ec_number
3.4.11.18
uniprot
proteins
function
FUNCTION: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle. {ECO:0000269|PubMed:16274222, ECO:0000269|PubMed:17114291}.
uniprot
proteins
mass_dalton
43215
uniprot
proteins
protein_family
Methionine aminopeptidase type 1 subfamily
uniprot
proteins
protein_family
Peptidase M24A family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16274222
uniprot
proteins
pubmed
16724298
uniprot
proteins
pubmed
16823043
uniprot
proteins
pubmed
17114291
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
7788527
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03174}.
uniprot
proteins