Eml4
entrez
78798
canonical
uniprot
Q3UMY5
canonical
ensembl
ENSMUSG00000032624
resolver
ensp
ENSMUSP00000041880
resolver
ensp
ENSMUSP00000094528
resolver
ensp
ENSMUSP00000107982
resolver
ensp
ENSMUSP00000157143
resolver
ensp
ENSMUSP00000157195
resolver
ensp
ENSMUSP00000318533
resolver
ensp
ENSMUSP00000318534
resolver
ensp
ENSMUSP00000318538
resolver
ensp
ENSMUSP00000318540
resolver
ensp
ENSMUSP00000331577
resolver
ensp
ENSMUSP00000331581
resolver
enst
ENSMUST00000049503
resolver
enst
ENSMUST00000096766
resolver
enst
ENSMUST00000112363
resolver
enst
ENSMUST00000234460
resolver
enst
ENSMUST00000234584
resolver
genesymbol
Eml4
resolver
uniprot
A0A0R4J0H0
resolver
uniprot
A0A0R4J1G7
resolver
uniprot
A0A3Q4EC14
resolver
uniprot
A0A3Q4EHV9
resolver
uniprot
A7ISP9
resolver
uniprot
F8WJ93
resolver
uniprot
Q6NS73
resolver
uniprot
Q6NXL8
resolver
uniprot
Q6NZJ8
resolver
uniprot
Q6P1A7
resolver
uniprot_entry
A0A0R4J0H0_MOUSE
resolver
uniprot_entry
A0A0R4J1G7_MOUSE
resolver
uniprot_entry
A0A3Q4EC14_MOUSE
resolver
uniprot_entry
A0A3Q4EHV9_MOUSE
resolver
uniprot_entry
A7ISP9_MOUSE
resolver
uniprot_entry
EMAL4_MOUSE
resolver
uniprot_entry
F8WJ93_MOUSE
resolver
uniprot_sec
Q6NS73
resolver
uniprot_sec
Q6NXL8
resolver
uniprot_sec
Q6NZJ8
resolver
uniprot_sec
Q6P1A7
resolver
amino_acid_sequence
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSMPSKGQPSLREAISMSCITNGSGISRKQNHTSSVSIARKETLSSAAKSGTEKKKEKPQGQREKKEDSHSNDQSPQIRASPSPQPSSQPLQINRQTPESKSSAPIKSIKRPPTAEKSHNSWENSDDSRNKLMKTVSTSKLISKVIKNADKHKDVIVNQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKLEWVYGYRGKDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVRCLAVHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVSLTTLHVIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEHMLTVWDWQKKSKIAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTMVEPPPGKGPKGVYQINRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNLEREIEVPDQYGTIRAVAEGRAEQFLVGTSRNFILRGTFNDGFQIEVQGHRDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYTVLENGRKYSRYGKCTGHSSYITHLDWSPDNKHIMSNSGDYEILYWDIENGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRRVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLPVPQNEVITDASVTKTPASSSETARPSNSPPLPPSLPLTGTAEEESRMGSSPTLVENSLEQIAEPSEEQSEWGSEDLGVVIDEEPASELSETQGATELPEEERGITPLC
uniprot
proteins
function
FUNCTION: Essential for the stability of microtubules (MTs) (PubMed:17196341). Essential for the formation of MTs (By similarity). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs (By similarity). Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression (By similarity). {ECO:0000250|UniProtKB:Q9HC35, ECO:0000269|PubMed:17196341}.
uniprot
proteins
mass_dalton
110027
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis (By similarity). Phosphorylation at Ser-144 and Ser-146 promotes its dissociation from microtubules during mitosis which is required for efficient chromosome congression (By similarity). {ECO:0000250|UniProtKB:Q9HC35}.
uniprot
proteins
protein_family
WD repeat EMAP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17196341
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
988
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17196341, ECO:0000305}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17196341}. Cytoplasm {ECO:0000250|UniProtKB:Q9HC35}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q9HC35}. Midbody {ECO:0000250|UniProtKB:Q9HC35}. Note=Localizes to microtubules (MTs) during interphase with a significantly reduced affinity for MTs during mitosis. {ECO:0000250|UniProtKB:Q9HC35}.
uniprot
proteins