F2rl3
entrez
14065
canonical
uniprot
O88634
canonical
ensembl
ENSMUSG00000050147
resolver
ensp
ENSMUSP00000054426
resolver
enst
ENSMUST00000058099
resolver
genesymbol
F2rl3
resolver
genesymbol_syn
Par4
resolver
uniprot
Q8BZ77
resolver
uniprot_entry
PAR4_MOUSE
resolver
uniprot_sec
Q8BZ77
resolver
amino_acid_sequence
MCWPLLYPLVLGLSISLAEGIQTPSIYDDVESTRGSHEGPLGPTVELKEPKSSDKPNPRGYPGKFCANDSDTLELPASSQALLLGWVPTRLVPALYGLVVAVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLAYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGQRLTTGLCLVAWLSAATLALPLTLHRQTFRLAGSDRMLCHDALPLTEQTSHWRPAFICLAVLGCFVPLLAMGLCYGATLRALAANGQRYSHALRLTALVLFSAVASFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRAMLCRQPEASSSSQASREAGSRGTAICSSTLL
uniprot
proteins
function
FUNCTION: Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
uniprot
proteins
mass_dalton
42786
uniprot
proteins
post_translational_modification
PTM: A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
9716134
uniprot
proteins
pubmed
9722561
uniprot
proteins
sequence_length
396
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 95..115; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 121..141; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 163..183; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 204..224; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 256..276; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 296..316; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 332..355; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins