Bbof1
entrez
72873
canonical
uniprot
Q3V079
canonical
ensembl
ENSMUSG00000057265
resolver
ensp
ENSMUSP00000080512
resolver
ensp
ENSMUSP00000168462
resolver
enst
ENSMUST00000081828
resolver
genesymbol
Bbof1
resolver
genesymbol_syn
Ccdc176
resolver
uniprot
B9EKT3
resolver
uniprot
Q9CUZ3
resolver
uniprot_entry
BBOF1_MOUSE
resolver
uniprot_sec
B9EKT3
resolver
uniprot_sec
Q9CUZ3
resolver
amino_acid_sequence
MPAKDKRKDKRKDKRKGKNKGKEPKKIIKSDEPAIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYNMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLAKTKEKAQEEKEKLEQKYALQVSELEGQFHQKAKEIGMIQTELKTIKQFQKRKIQVEKELDDLKENLRNSEKNYQETLRRLESRFFEEKHRLEQEAEKRIIMLAERAHHEAVVQLNTAGRNVFKENVYLHKALAYHLKEAEILQQNSKKIEENHSCLLQQKEINDLLVKEKIMQLTQQKSQIQTLQKKVVSLENALTYMTTEFEAEVLKLQQKAIIENQAGLVEIDKLQQLLQMKDREMNRVKRLAKNILDERTEVEQFFLDALYEVKQQILASRKHYKQIAQAAFNLKMRAACAGKTEYPRIRTFDGKEQSTNSVNQDLLEAEKWPTTQKNVDIRDLTWEQKEKVLRLLFAKMNGFAARKYSQSSKPPVPDHIIYGSGEMKETGDENNLLDQTFITQQAPVSDSNRMVSPDVIPQGLQDSDIA
uniprot
proteins
function
FUNCTION: Plays an essential role in sperm motility and male fertility by stabilizing the sperm flagellar axonemal structure. May be required for the stability of ODF2 and MANS1 proteins. Dispensable for the assembly and function of motile cilia. {ECO:0000269|PubMed:37198331}.
uniprot
proteins
mass_dalton
62499
uniprot
proteins
protein_family
BBOF1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
37198331
uniprot
proteins
sequence_length
533
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A0JMY4}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37198331}. Note=Localizes to a polar structure adjacent to the basal body. {ECO:0000250|UniProtKB:A0JMY4}.
uniprot
proteins