STX6
entrez
10228
canonical
uniprot
O43752
canonical
ensembl
ENSG00000135823
resolver
ensp
ENSP00000258301
resolver
ensp
ENSP00000440188
resolver
genesymbol
STX6
resolver
hgnc
HGNC:11441
resolver
uniprot
B2R652
resolver
uniprot
B4DR17
resolver
uniprot
Q5VY08
resolver
uniprot
Q6FH83
resolver
uniprot_entry
STX6_HUMAN
resolver
uniprot_sec
B2R652
resolver
uniprot_sec
B4DR17
resolver
uniprot_sec
Q5VY08
resolver
uniprot_sec
Q6FH83
resolver
amino_acid_sequence
MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLVL
uniprot
proteins
function
FUNCTION: SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. {ECO:0000250|UniProtKB:Q63635}.
uniprot
proteins
mass_dalton
29176
uniprot
proteins
protein_family
Syntaxin family
uniprot
proteins
pubmed
10080545
uniprot
proteins
pubmed
11384996
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17159904
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20163565
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23818989
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28626000
uniprot
proteins
pubmed
35499567
uniprot
proteins
sequence_length
255
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:23818989}; Single-pass type IV membrane protein {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 235..255; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins