Pnpla7
entrez
246246
canonical
uniprot
Q5BK26
canonical
ensembl
ENSRNOG00000008190
resolver
ensp
ENSRNOP00000011633
resolver
ensp
ENSRNOP00000112741
resolver
enst
ENSRNOT00000011633
resolver
enst
ENSRNOT00000141487
resolver
genesymbol
Pnpla7
resolver
genesymbol_syn
Nre
resolver
genesymbol_syn
Ntel1
resolver
uniprot
A0ABK0M1C2
resolver
uniprot
G3V745
resolver
uniprot
Q5XIX2
resolver
uniprot
Q8K3H9
resolver
uniprot_entry
A0ABK0M1C2_RAT
resolver
uniprot_entry
G3V745_RAT
resolver
uniprot_entry
PLPL7_RAT
resolver
uniprot_sec
Q5XIX2
resolver
uniprot_sec
Q8K3H9
resolver
amino_acid_sequence
MQKEEDVCPEAGYCLGTALSSWGLHFMEEHSQSTMLMGIGIGVLLTLAFVGLAAFFVYRKVSRFRRAEPIPQYRFRKRDKVMFYGRKIMRKVTTLPHTLVGNTAAPRQRVRKRTKVLSLAKRILRFKKEYPTLQPKEPPPSLLEADLTEFDVKNSHLPSEVLYMLKNVRVLGHFEKPLFLELCKHMVFVQLQEGEHVFQPGEPDISIYVVQDGRLEVCIQDADGTEVVVKEVLPGDSVHSLLSILDVITGHTAPYKTVSARAAVASTVLWLPAAAFQGVFEKYPETLVRVVQIIMVRLQRVTFLALHNYLGLTTELFNPESQAIPLLSVASVAGRAKRQMSYGPEEQLERSPRLSEFNSSDQRSVAVSGPLLKRSCSVPLPPIHGEIDELRQAQGSGSNTSAFQESQEGATSDLGMAYNRARILPHSEEQLGSSLASKSKKSVVAETSAVFHYSEKPRDEPGPSGRTDAIFRAATKDLLTLMKLDDPSLLDGRVAFLHVPAGTIVSKQGDQDVNILFVVSGMLHVYQQKIDSLEDTCLFLTHPGEMVGQLAVLTGEPLMFTIRANRDCSFLSISKAHFYEIMRKRPDVVLGVAHTVVRRMSSFVRQIDFALDWMEVEAGRAIYRQGDKSDCTYIVLSGRLRSVIRKDDGKKRLAGEYGRGDLVGVVEMLTHQARATTVHAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKILGSLQQGSGTGHQLGFNTASSKWDLGNPPGNLSTVAAMPVSEDVPLTAFALELQHALSAIGPVLLLTSDNIKQRLGSAALDSIHEYRLSSWLGQQEDIHRIVLYQADSTLTPWTQRCIRQADCILIVGLGDQEPALGELEQMLESTAVRAQKQLILLHKEEGPAPSRTVEWLNMRSWCSGHLHLCCPRRVFSKRSLPKLVEMYTRIFQRPPDRHSDFSRLARILTGNAIALVLGGGGARGCAQVGILRALAECGIPVDIIGGTSIGAFMGALFAEERSYSQIRIRAKQWAEDMTSMVKTILDLTYPITSMFSGTGFNSSISNIFKDRQIEDLWLPYFAITTDITASAMRVHTDGALWRYVRASMSLSGYMPPLCDPKDGHLLMDGGYINNLPADVARSMGAKVVIAIDVGSRDETDLTNYGDALSGWWLLWKRWNPLATKVKVLNMAEIQTRLAYVCCVRQLEMVKNSDYCEYLRPPIDSYRTLDFGKFDEICEVGYQHGPAGFDIWVRSGVLEKMLQDQQGTSKRMDCGVFTCPNSSFTDLAEIVSRIEPAKVAAVDDESDYQTEYEEELPAIPKETYADFQSTGIELDSDSECEPSMSQGPHSLTSPKQSQDSFPWLPNQDDQGPRLYRPS
uniprot
proteins
ec_number
3.1.1.-
uniprot
proteins
ec_number
3.1.1.5
uniprot
proteins
function
FUNCTION: Lysophospholipase which preferentially deacylates unsaturated lysophosphatidylcholine (C18:1), generating glycerophosphocholine. Also can deacylate, to a lesser extent, lysophosphatidylethanolamine (C18:1), lysophosphatidyl-L-serine (C18:1) and lysophosphatidic acid (C16:0). {ECO:0000250|UniProtKB:A2AJ88}.
uniprot
proteins
mass_dalton
150024
uniprot
proteins
mutagenesis
MUTAGEN 980; /note="S->A,C,D,H: Abolishes hydrolytic activity."; /evidence="ECO:0000269|PubMed:12893290
uniprot
proteins
protein_family
NTE family
uniprot
proteins
pubmed
12893290
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1349
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A2AJ88}; Single-pass type III membrane protein {ECO:0000250|UniProtKB:A2AJ88}. Lipid droplet {ECO:0000250|UniProtKB:A2AJ88}.
uniprot
proteins
transmembrane_region
TRANSMEM 37..57; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins