METTL21A
entrez
151194
canonical
uniprot
Q8WXB1
canonical
ensembl
ENSG00000144401
resolver
ensp
ENSP00000272839
resolver
ensp
ENSP00000385481
resolver
ensp
ENSP00000389684
resolver
ensp
ENSP00000392062
resolver
ensp
ENSP00000400730
resolver
ensp
ENSP00000407622
resolver
ensp
ENSP00000415115
resolver
ensp
ENSP00000416570
resolver
ensp
ENSP00000531120
resolver
ensp
ENSP00000531121
resolver
ensp
ENSP00000673937
resolver
ensp
ENSP00000673938
resolver
ensp
ENSP00000673940
resolver
ensp
ENSP00000673941
resolver
ensp
ENSP00000673944
resolver
ensp
ENSP00000673945
resolver
ensp
ENSP00000673946
resolver
ensp
ENSP00000673947
resolver
ensp
ENSP00000673949
resolver
ensp
ENSP00000697420
resolver
ensp
ENSP00000697425
resolver
ensp
ENSP00000697426
resolver
ensp
ENSP00000697427
resolver
ensp
ENSP00000697428
resolver
ensp
ENSP00000732941
resolver
ensp
ENSP00000760710
resolver
enst
ENST00000272839
resolver
enst
ENST00000432416
resolver
enst
ENST00000861061
resolver
enst
ENST00000861062
resolver
genesymbol
METTL21A
resolver
genesymbol_syn
FAM119A
resolver
genesymbol_syn
HCA557B
resolver
hgnc
HGNC:30476
resolver
uniprot
C9JES0
resolver
uniprot
H7BXH9
resolver
uniprot
Q53RV0
resolver
uniprot
Q8N1Z9
resolver
uniprot
Q96GH6
resolver
uniprot_entry
C9JES0_HUMAN
resolver
uniprot_entry
H7BXH9_HUMAN
resolver
uniprot_entry
MT21A_HUMAN
resolver
uniprot_sec
Q53RV0
resolver
uniprot_sec
Q8N1Z9
resolver
uniprot_sec
Q96GH6
resolver
amino_acid_sequence
MALVPYEETTEFGLQKFHKPLATFSFANHTIQIRQDWRHLGVAAVVWDAAIVLSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQTKTVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVILLACRIRYERDNNFLAMLERQFTVRKVHYDPEKDVHIYEAQKRNQKEDL
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8. {ECO:0000269|PubMed:22948820, ECO:0000269|PubMed:23349634, ECO:0000269|PubMed:23921388}.
uniprot
proteins
mass_dalton
24600
uniprot
proteins
mutagenesis
MUTAGEN 94; /note="D->A: Abolishes methyltransferase activity."; /evidence="ECO:0000269|PubMed:22948820
uniprot
proteins
protein_family
METTL21 family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
22948820
uniprot
proteins
pubmed
23349634
uniprot
proteins
pubmed
23921388
uniprot
proteins
sequence_length
218
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23349634}.
uniprot
proteins