Mboat2
entrez
67216
canonical
uniprot
Q8R3I2
canonical
ensembl
ENSMUSG00000020646
resolver
ensp
ENSMUSP00000077937
resolver
ensp
ENSMUSP00000106567
resolver
ensp
ENSMUSP00000152348
resolver
ensp
ENSMUSP00000230238
resolver
genesymbol
Mboat2
resolver
genesymbol_syn
Lpcat4
resolver
genesymbol_syn
Oact2
resolver
uniprot
A9EDS7
resolver
uniprot
Q8BHH5
resolver
uniprot
Q8BM56
resolver
uniprot
Q8BN01
resolver
uniprot
Q8R192
resolver
uniprot
Q9CZ73
resolver
uniprot_entry
MBOA2_MOUSE
resolver
uniprot_entry
Q8BN01_MOUSE
resolver
uniprot_sec
A9EDS7
resolver
uniprot_sec
Q8BHH5
resolver
uniprot_sec
Q8BM56
resolver
uniprot_sec
Q8R192
resolver
uniprot_sec
Q9CZ73
resolver
activity_regulation
ACTIVITY REGULATION: Partially inhibited by thimerosal. {ECO:0000250|UniProtKB:Q6ZWT7}.
uniprot
proteins
amino_acid_sequence
MATTSTTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAVWFRTYLHSSKTSSFIRHVVATLLGLYLAFFCFGWYALHFLVQSGISYCIMIIAGVESMQQCCFVFALGYLSVCQITRVYIFDYGQYSADFSGPMMIITQKITSLAYEIHDGMFRKDEELTPSQRGLAVRRMPSLLEYVSYTCNFMGILAGPLCSYKDYIAFIEGRASHVAQPSENGKDEQHGKADPSPNAAVTEKLLVCGLSLLFHLTISNMLPVEYNIDEHFQATASWPTKATYLYVSLLAARPKYYFAWTLADAINNAAGFGFRGYDKNGVARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERATFSPTIQTFFLSAIWHGVYPGYYLTFLTGVLMTLAARAVRNNFRHYFLEPPQLKLFYDLITWVATQITISYTVVPFVLLSIKPSFTFYSSWYYCLHVCSILVLLLLPVKKSQRRTSTQENVHLSQAKKFDERDNPLGQNSFSTMNNVCNQNRDTGSRHSSLTQ
uniprot
proteins
ec_number
2.3.1.-
uniprot
proteins
ec_number
2.3.1.23
uniprot
proteins
ec_number
2.3.1.n7
uniprot
proteins
function
FUNCTION: Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (PubMed:18287005, PubMed:29196633). Catalyzes the acylation of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) and to a lesser extend lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) (PubMed:18287005, PubMed:29196633). Does not acylates lysophosphatidic acid (LPA) and lysophosphatidylserine (PubMed:18287005). Prefers oleoyl-CoA as the acyl donor (PubMed:18287005, PubMed:29196633). May be involved in chondrocyte differentiation (PubMed:29196633). {ECO:0000269|PubMed:18287005, ECO:0000269|PubMed:29196633}.
uniprot
proteins
mass_dalton
58995
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; phospholipid metabolism. {ECO:0000269|PubMed:18287005}.
uniprot
proteins
protein_family
Membrane-bound acyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17890783
uniprot
proteins
pubmed
18287005
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29196633
uniprot
proteins
sequence_length
519
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18287005}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 61..81; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 184..204; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 236..256; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 263..283; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 365..385; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 415..435; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 443..463; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins