Cnmd
entrez
16840
canonical
uniprot
Q9Z1F6
canonical
ensembl
ENSMUSG00000022025
resolver
ensp
ENSMUSP00000022603
resolver
ensp
ENSMUSP00000126958
resolver
ensp
ENSMUSP00000228319
resolver
ensp
ENSMUSP00000228320
resolver
enst
ENSMUST00000022603
resolver
enst
ENSMUST00000165835
resolver
genesymbol
Cnmd
resolver
genesymbol_syn
Chmd
resolver
genesymbol_syn
Chmi
resolver
genesymbol_syn
Lect1
resolver
uniprot
G5E8Z6
resolver
uniprot
Q80UX1
resolver
uniprot
Q9CXU5
resolver
uniprot_entry
CNMD_MOUSE
resolver
uniprot_entry
G5E8Z6_MOUSE
resolver
uniprot_sec
Q80UX1
resolver
uniprot_sec
Q9CXU5
resolver
amino_acid_sequence
MTENSDKVPITMVGPEDVEFCSPPAYTTVTVKPSGSPTRLLKVGAVVLISGAVLLLFGAIGAFYFWKGNDNHIYNVHYSMSINGKLQDGSMEIDAVNNLETFKMGSGAEEAIEVNDFKNGITGIRFAGGEKCYIKAQVKARIPEVGTVTKQSISELEGKIMPANYEENSLIWVAVDQPVKDSSFLSSKILELCGDLPIFWLKPMYPKEIQRERREVVRNSAPSTTRRPHSEPRGNAGPGRLSNGTRPNVQDDAEPFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVVMPCSWWVARILGMV
uniprot
proteins
function
FUNCTION: Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development (By similarity). Inhibits in vitro tube formation and mobilization of endothelial cells (By similarity). Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization. {ECO:0000250, ECO:0000269|PubMed:16980969}.
uniprot
proteins
mass_dalton
37225
uniprot
proteins
post_translational_modification
PTM: After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein. {ECO:0000250}.
uniprot
proteins
protein_family
Chondromodulin-1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16980969
uniprot
proteins
sequence_length
334
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Chondromodulin-1]: Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Accumulated in the inter-territorial matrix of cartilage. {ECO:0000250}.; SUBCELLULAR LOCATION: [Chondrosurfactant protein]: Endomembrane system {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 46..66; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins