Lipt1
entrez
623661
canonical
uniprot
Q8VCM4
canonical
ensembl
ENSMUSG00000037216
resolver
ensp
ENSMUSP00000038739
resolver
ensp
ENSMUSP00000315445
resolver
ensp
ENSMUSP00000315446
resolver
ensp
ENSMUSP00000315447
resolver
ensp
ENSMUSP00000315450
resolver
ensp
ENSMUSP00000315451
resolver
enst
ENSMUST00000041621
resolver
genesymbol
Lipt1
resolver
genesymbol_syn
EG623661
resolver
uniprot
Q8C894
resolver
uniprot_entry
LIPT_MOUSE
resolver
uniprot_entry
Q8C894_MOUSE
resolver
amino_acid_sequence
MLIPLSMKNCFRLLCQHKVPAAGFKSPPTHGLILQSISNDVYENLAFEDWIHDHIHLEGKPILFLWRNSPSVVIGRHQNPWQECNLHLMRQEGIKLARRKSGGGAVYHDMGNINLTFFTTKTKYDRMENLKLIVRALNAVQPQLDVQPTKKFDLLLDGQFKISGTASKIGRTAAYHHCTLLCSTNRTALSSSLKSPYCGIKSNATPSIPSAVKNLLERDSTLTCEVLMSAVAAEYAAHHQVDGHVNLINPADETMFPGINRKVKELQSWEWVYGRTPKFTVDTTFHVPYEQAHLEIQVFMDVKNGRIETCAIKAPDHWLPLEIGEKLNSSFIGSKFCPVETTLLTNVLLRTCPGDHHLHSKWYILCEKIRGIM
uniprot
proteins
ec_number
2.3.1.-
uniprot
proteins
ec_number
2.3.1.200
uniprot
proteins
function
FUNCTION: Lipoyl amidotransferase that catalyzes the transfer of lipoyl moieties from lipoyl-protein H of the glycine cleavage system (lipoyl-GCSH) to E2 subunits of the pyruvate dehydrogenase complex (PDCE2). Unable to catalyze the transfer of octanoyl from octanoyl-GCSH to PDCE2 (By similarity). In vitro, it is also able to catalyze the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes but this reaction may not be physiologically relevant (By similarity). {ECO:0000250|UniProtKB:O46419, ECO:0000250|UniProtKB:Q9Y234}.
uniprot
proteins
mass_dalton
42146
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.
uniprot
proteins
protein_family
LplA family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:O46419}.
uniprot
proteins