Mbp
entrez
24547
canonical
uniprot
P02688
canonical
ensembl
ENSRNOG00000016516
resolver
ensp
ENSRNOP00000022303
resolver
ensp
ENSRNOP00000055098
resolver
ensp
ENSRNOP00000086141
resolver
ensp
ENSRNOP00000101389
resolver
enst
ENSRNOT00000022303
resolver
enst
ENSRNOT00000058296
resolver
enst
ENSRNOT00000107098
resolver
enst
ENSRNOT00000122345
resolver
genesymbol
Mbp
resolver
uniprot
A0A8I6A591
resolver
uniprot
A0A8L2QCF0
resolver
uniprot
A0A8L2QRV9
resolver
uniprot
A0ABK0LJ84
resolver
uniprot
A6K5J1
resolver
uniprot
I7FKL4
resolver
uniprot
Q505J1
resolver
uniprot
Q5XFW1
resolver
uniprot
Q8R4K6
resolver
uniprot
Q9Z1J4
resolver
uniprot
Q9Z1J5
resolver
uniprot
Q9Z1J6
resolver
uniprot_entry
A0A8I6A591_RAT
resolver
uniprot_entry
A0A8L2QCF0_RAT
resolver
uniprot_entry
A0A8L2QRV9_RAT
resolver
uniprot_entry
A0ABK0LJ84_RAT
resolver
uniprot_entry
A6K5J1_RAT
resolver
uniprot_entry
I7FKL4_RAT
resolver
uniprot_entry
MBP_RAT
resolver
uniprot_entry
Q5XFW1_RAT
resolver
uniprot_sec
Q505J1
resolver
uniprot_sec
Q8R4K6
resolver
uniprot_sec
Q9Z1J4
resolver
uniprot_sec
Q9Z1J5
resolver
uniprot_sec
Q9Z1J6
resolver
amino_acid_sequence
MASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSGDRGAPKRGSGKVPWLKQSRSPLPSHARSRPGLCHMYKDSHTRTTHYGSLPQKSQRTQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGYGGRASDYKSAHKGFKGAYDAQGTLSKIFKLGGRDSRSGSPMARR
uniprot
proteins
function
FUNCTION: Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
21502
uniprot
proteins
post_translational_modification
PTM: As in other animals, several charge isomers may be produced as a result of optional post-translational modifications, such as phosphorylation of serine or threonine residues, deamidation of glutamine or asparagine residues, citrullination and methylation of arginine residues. {ECO:0000269|PubMed:4141893, ECO:0000269|Ref.10}.; PTM: Arg-131 was found to be 44% monomethylated and 11% symmetrically dimethylated.; PTM: Phosphorylated by TAOK2, VRK2, MAPK11, MAPK12, MAPK14 and MINK1. {ECO:0000250}.; PTM: Proteolytically cleaved in B cell lysosomes by cathepsin CTSG which degrades the major immunogenic MBP epitope and prevents the activation of MBP-specific autoreactive T cells. {ECO:0000250|UniProtKB:P02686}.
uniprot
proteins
protein_family
Myelin basic protein family
uniprot
proteins
pubmed
14580679
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2429678
uniprot
proteins
pubmed
4122324
uniprot
proteins
pubmed
4141893
uniprot
proteins
pubmed
6194889
uniprot
proteins
pubmed
7578863
uniprot
proteins
sequence_length
195
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
uniprot
proteins