Mvp
entrez
78388
canonical
uniprot
Q9EQK5
canonical
ensembl
ENSMUSG00000030681
resolver
ensp
ENSMUSP00000119213
resolver
ensp
ENSMUSP00000127250
resolver
ensp
ENSMUSP00000346487
resolver
enst
ENSMUST00000133172
resolver
enst
ENSMUST00000165096
resolver
genesymbol
Mvp
resolver
uniprot
E9Q3X0
resolver
uniprot
Q3U7S9
resolver
uniprot
Q922X6
resolver
uniprot_entry
E9Q3X0_MOUSE
resolver
uniprot_entry
MVP_MOUSE
resolver
uniprot_entry
Q3U7S9_MOUSE
resolver
uniprot_sec
Q922X6
resolver
amino_acid_sequence
MATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPVRMVTVPPRHYCIVANPVSRDAQSSVLFDVTGQVRLRHADQEIRLAQDPFPLYPGELLEKDITPLQVVLPNTALHLKALLDFEDKNGDKVMAGDEWLFEGPGTYIPQKEVEVVEIIQATVIKQNQALRLRARKECFDRDGKERVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRARQNFKDLRGVAHRTGEEWLVTVQDTEAHVPDVYEEVLGVVPITTLGPRHYCVILDPMGPDGKNQLGQKRVVKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLKALQPLEEGEGEEKVAHQAGDRWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPSGVEELLNLGHDPLADRGQKGTAKVLQPSAARNKTRVVSYRVPHNAAVQVYDYRAKRARVVFGPELVSLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFELKNRNDPEETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRMAVFGFEMSEDAGPDGALLPRARDRAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELIYSRAQLELEVSKAQQLADVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSSPINLFNTAFGLLGLGSDGQPPVQK
uniprot
proteins
function
FUNCTION: Structural component of the vault particle, which is a massive ribonucleoprotein complex that may play a role in cargo transport and signal transduction (By similarity). Oligomerizes to form a cage-like vault complex, which can house several minor vault components including PARP4 (By similarity). Vaults may play a role in nucleo-cytoplasmic transport (By similarity). Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK (By similarity). Down-regulates SRC activity and signaling through MAP kinases (By similarity). {ECO:0000250|UniProtKB:Q14764}.
uniprot
proteins
mass_dalton
95924
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on Tyr residues after EGF stimulation (By similarity). {ECO:0000250|UniProtKB:Q14764}.; PTM: Dephosphorylated by PTPN11 (By similarity). {ECO:0000250|UniProtKB:Q14764}.
uniprot
proteins
protein_family
Major vault protein family
uniprot
proteins
pubmed
11149928
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19779459
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
861
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q14764}. Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q14764}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q14764}.
uniprot
proteins