MLX
entrez
6945
canonical
uniprot
Q9UH92
canonical
ensembl
ENSG00000108788
resolver
ensp
ENSP00000246912
resolver
ensp
ENSP00000320913
resolver
ensp
ENSP00000416627
resolver
genesymbol
MLX
resolver
genesymbol_syn
BHLHD13
resolver
genesymbol_syn
TCFL4
resolver
hgnc
HGNC:11645
resolver
uniprot
A8K2J3
resolver
uniprot
B2RAV8
resolver
uniprot
B2RD73
resolver
uniprot
Q53XM6
resolver
uniprot
Q96FL2
resolver
uniprot
Q9H2V0
resolver
uniprot
Q9H2V1
resolver
uniprot
Q9H2V2
resolver
uniprot
Q9NXN3
resolver
uniprot_entry
MLX_HUMAN
resolver
uniprot_sec
A8K2J3
resolver
uniprot_sec
B2RAV8
resolver
uniprot_sec
B2RD73
resolver
uniprot_sec
Q53XM6
resolver
uniprot_sec
Q96FL2
resolver
uniprot_sec
Q9H2V0
resolver
uniprot_sec
Q9H2V1
resolver
uniprot_sec
Q9H2V2
resolver
uniprot_sec
Q9NXN3
resolver
amino_acid_sequence
MTEPGASPEDPWVKASPVGAHAGEGRAGRARARRGAGRRGASLLSPKSPTLSVPRGCREDSSHPACAKVEYAYSDNSLDPGLFVESTRKGSVVSRANSIGSTSASSVPNTDDEDSDYHQEAYKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCKPQTLREIVIGVLHQLKNQLY
uniprot
proteins
function
FUNCTION: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. {ECO:0000269|PubMed:10593926, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}.
uniprot
proteins
mass_dalton
33300
uniprot
proteins
pubmed
10593926
uniprot
proteins
pubmed
10918583
uniprot
proteins
pubmed
12446771
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16782875
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform Alpha]: Cytoplasm {ECO:0000269|PubMed:10918583}. Note=Found predominantly in the cytoplasm (PubMed:10918583). {ECO:0000269|PubMed:10918583}.; SUBCELLULAR LOCATION: [Isoform Beta]: Cytoplasm {ECO:0000269|PubMed:10918583}. Note=Found predominantly in the cytoplasm (PubMed:10918583). {ECO:0000269|PubMed:10918583}.; SUBCELLULAR LOCATION: [Isoform Gamma]: Nucleus {ECO:0000269|PubMed:10918583}. Note=Found predominantly in the nucleus (PubMed:10918583). {ECO:0000269|PubMed:10918583}.
uniprot
proteins