Ttyh1
entrez
292597
canonical
uniprot
P0C5X8
canonical
ensembl
ENSRNOG00000032699
resolver
ensembl
ENSRNOG00055016212
resolver
ensembl
ENSRNOG00060028417
resolver
ensembl
ENSRNOG00065030690
resolver
ensp
ENSRNOP00000062088
resolver
ensp
ENSRNOP00055022110
resolver
ensp
ENSRNOP00060041324
resolver
ensp
ENSRNOP00065043464
resolver
enst
ENSRNOT00000068459
resolver
enst
ENSRNOT00055027541
resolver
enst
ENSRNOT00060049547
resolver
enst
ENSRNOT00065052929
resolver
genesymbol
Ttyh1
resolver
uniprot
B4F773
resolver
uniprot_entry
B4F773_RAT
resolver
uniprot_entry
TTYH1_RAT
resolver
amino_acid_sequence
MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALQHANHTLSTIDDLVLETVERLGEAVRTELTTLEEVLSERVELVAATRGARRQAEAAAQHLQGLAFWQGVSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGISSDILNYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREASPQFPAAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI
uniprot
proteins
function
FUNCTION: Calcium-independent, swelling-dependent volume-regulated anion channel (VRAC-swell) which plays a pivotal role in the process of regulatory volume decrease (RVD) in the brain through the efflux of anions like chloride and organic osmolytes like glutamate. {ECO:0000250|UniProtKB:Q9D3A9}.
uniprot
proteins
mass_dalton
49032
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. Contains high-mannose, hybrid and complex oligosaccharides. {ECO:0000250|UniProtKB:Q9H313}.
uniprot
proteins
protein_family
Tweety family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
17116230
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
450
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17116230}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 44..64; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 89..109; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 215..235; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 241..261; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 391..411; /note="Helical; Name=5"; /evidence="ECO:0000255
uniprot
proteins