Mks1
entrez
287612
canonical
uniprot
Q499Q5
canonical
ensembl
ENSRNOG00000008635
resolver
ensp
ENSRNOP00000011500
resolver
ensp
ENSRNOP00000112136
resolver
enst
ENSRNOT00000011500
resolver
genesymbol
Mks1
resolver
uniprot
F1LSL4
resolver
uniprot_entry
F1LSL4_RAT
resolver
uniprot_entry
MKS1_RAT
resolver
amino_acid_sequence
MAEAVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAQMGKDLIDLATFKPPQAASGHRPDEEEEEEVIIGWQEKLFSQFEVDLYQNESACQSPLDHQYRQEVLKLENSGGRKNRRIFTYTDSDRYTDLEEYCQKITTSAGEAPSFLVERMANVRRRRQDRRGVEGSKLKSRIITWEPSEDFIRNSHAINTPLQTMYIMADLGPYGKLGYKIHEHVLCVLKVDSNGVITVKPDFTGIKGPYRIETEGEKQEHTSAWKYTIDNVSSLAQPEEEEREQRVFKDLYGRHKEYLSSLVGTDFEMIAPGALRLFVNGEVVSARGYEHDNLYVHFFVELPATNWSSPSFQQLSGVTQTCVTRSLGMDKVAYFSFPFTFEAFFLHEDESDESLPEWPVLYCKVLSLDFWQRYRVEGYGAVVLPVTPGSHTLTASTWRPMELGLVAELRRFFIGGSLELEDPSYVRIPGTFKGERLSRFGFRTETTGTVTFRLHCLQQSRAFMESNSLRKQMRSVLDRLEGFSQQSSTHNVLEAFRRARRRMQEARESLPQDLVSPTGTLA
uniprot
proteins
function
FUNCTION: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. {ECO:0000250, ECO:0000269|PubMed:19515853}.
uniprot
proteins
mass_dalton
64523
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19515853
uniprot
proteins
sequence_length
561
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}.
uniprot
proteins