Tgm1
entrez
21816
canonical
uniprot
Q9JLF6
canonical
ensembl
ENSMUSG00000022218
resolver
ensp
ENSMUSP00000002389
resolver
ensp
ENSMUSP00000128090
resolver
ensp
ENSMUSP00000137642
resolver
ensp
ENSMUSP00000335045
resolver
enst
ENSMUST00000002389
resolver
enst
ENSMUST00000168729
resolver
enst
ENSMUST00000178034
resolver
genesymbol
Tgm1
resolver
uniprot
A0A0R4J293
resolver
uniprot
Q8R0T9
resolver
uniprot_entry
A0A0R4J293_MOUSE
resolver
uniprot_entry
TGM1_MOUSE
resolver
uniprot_sec
Q8R0T9
resolver
amino_acid_sequence
MEGPRSDVGRWGRSPWQPPTTPSPEPEPEPEPDRRSRSRRGGGRSFWARCCGCCSCGNRGDDDWGPEPSGSRSRGTSSRGRDSRGGRRPESRGSGVNAAGDGTIREGMLVVTGVDLLCSRSDQNRREHHTDEFEYDELIVRRGQPFHMILFLNREYESSDRIALELLIGSNPEVGKGTHVIIPVGKGGSGGWKAQVTKNNGHNLNLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGFATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESVKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAIHSNNREDITHIYKHPEGSEAERRAVEKAAAHGSKPNVYATRDSAEDVAMQVEAQDAVMGQDLAVSVVLTNRGSSRRTVKLHLYLCVTYYTGVSGPTFKEAKKEVTLAPGASDSVTMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECGVQIVFKNPLPVTLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPASGGSGFSDAGGDSRSGENIPMAYRGGA
uniprot
proteins
ec_number
2.3.2.13
uniprot
proteins
function
FUNCTION: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity). {ECO:0000250|UniProtKB:P22735}.
uniprot
proteins
mass_dalton
89826
uniprot
proteins
post_translational_modification
PTM: Tyrosine-phosphorylated. {ECO:0000269|PubMed:10567386}.; PTM: The N-terminus is blocked. {ECO:0000250|UniProtKB:P22735}.; PTM: Activated by proteolytic processing. {ECO:0000250|UniProtKB:P22735}.; PTM: Myristoylated. {ECO:0000250|UniProtKB:P22735}.; PTM: Palmitoylated. {ECO:0000250|UniProtKB:P22735}.; PTM: The membrane anchorage region possesses a cluster of five cysteines within which fatty acid(s) may become thioester-linked. It is subject to phorbol ester-stimulated phosphorylation and is hypersensitive to proteolysis, which releases the enzyme in a soluble form. {ECO:0000250|UniProtKB:P22735}.
uniprot
proteins
protein_family
Transglutaminase family
uniprot
proteins
protein_family
Transglutaminase superfamily
uniprot
proteins
pubmed
10567386
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
815
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P22735}; Lipid-anchor {ECO:0000250|UniProtKB:P22735}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P22735}. Note=Myristoylation and palmitoylation mediate the membrane localization. {ECO:0000250|UniProtKB:P22735}.
uniprot
proteins