Sod1
entrez
24786
canonical
uniprot
P07632
canonical
ensembl
ENSRNOG00000002115
resolver
ensp
ENSRNOP00000002885
resolver
enst
ENSRNOT00000002885
resolver
genesymbol
Sod1
resolver
uniprot_entry
SODC_RAT
resolver
amino_acid_sequence
MAMKAVCVLKGDGPVQGVIHFEQKASGEPVVVSGQITGLTEGEHGFHVHQYGDNTQGCTTAGPHFNPHSKKHGGPADEERHVGDLGNVAAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ
uniprot
proteins
ec_number
1.15.1.1
uniprot
proteins
ec_number
1.8.-.-
uniprot
proteins
function
FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Catalyzes the oxidation of hydrogen sulfide (H2S) to sulfate, playing an important role in detoxifying H2S and limiting the accumulation of reactive sulfur species (RSS) such as persulfides and polysulfides. {ECO:0000250|UniProtKB:P00441}.
uniprot
proteins
mass_dalton
15912
uniprot
proteins
post_translational_modification
PTM: Palmitoylation helps nuclear targeting and decreases catalytic activity. {ECO:0000250|UniProtKB:P00441}.; PTM: Succinylation, adjacent to copper catalytic site, probably inhibits activity. Desuccinylation by SIRT5 enhances activity. {ECO:0000250|UniProtKB:P00441}.
uniprot
proteins
protein_family
Cu-Zn superoxide dismutase family
uniprot
proteins
pubmed
1379810
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2703531
uniprot
proteins
pubmed
3595611
uniprot
proteins
pubmed
3628012
uniprot
proteins
pubmed
3790250
uniprot
proteins
pubmed
8224914
uniprot
proteins
pubmed
8837775
uniprot
proteins
sequence_length
154
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P00441}. Nucleus {ECO:0000250|UniProtKB:P00441}.
uniprot
proteins