S1PR5
entrez
53637
canonical
uniprot
Q9H228
canonical
ensembl
ENSG00000180739
resolver
ensp
ENSP00000328472
resolver
ensp
ENSP00000416915
resolver
genesymbol
S1PR5
resolver
genesymbol_syn
EDG8
resolver
hgnc
HGNC:14299
resolver
uniprot
Q6NW11
resolver
uniprot_entry
S1PR5_HUMAN
resolver
uniprot_sec
Q6NW11
resolver
amino_acid_sequence
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
uniprot
proteins
function
FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. {ECO:0000250}.
uniprot
proteins
mass_dalton
41775
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11705398
uniprot
proteins
pubmed
12044878
uniprot
proteins
pubmed
12234605
uniprot
proteins
pubmed
12427546
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15530552
uniprot
proteins
sequence_length
398
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 41..61; /note="Helical; Name=1"; /evidence="ECO:0000250"; TRANSMEM 71..91; /note="Helical; Name=2"; /evidence="ECO:0000250"; TRANSMEM 112..132; /note="Helical; Name=3"; /evidence="ECO:0000250"; TRANSMEM 152..172; /note="Helical; Name=4"; /evidence="ECO:0000250"; TRANSMEM 193..213; /note="Helical; Name=5"; /evidence="ECO:0000250"; TRANSMEM 253..273; /note="Helical; Name=6"; /evidence="ECO:0000250"; TRANSMEM 288..308; /note="Helical; Name=7"; /evidence="ECO:0000250
uniprot
proteins