Cdk10
entrez
234854
canonical
uniprot
Q3UMM4
canonical
ensembl
ENSMUSG00000033862
resolver
ensp
ENSMUSP00000045527
resolver
ensp
ENSMUSP00000148435
resolver
ensp
ENSMUSP00000287145
resolver
enst
ENSMUST00000036880
resolver
enst
ENSMUST00000213005
resolver
genesymbol
Cdk10
resolver
uniprot
A0A1D5RLN0
resolver
uniprot
Q0VH02
resolver
uniprot
Q3UZD2
resolver
uniprot_entry
A0A1D5RLN0_MOUSE
resolver
uniprot_entry
CDK10_MOUSE
resolver
uniprot_entry
Q0VH02_MOUSE
resolver
uniprot_sec
Q3UZD2
resolver
amino_acid_sequence
MAEVDLESDQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIMLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATSGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPAAAEGQSKRCRP
uniprot
proteins
ec_number
2.7.11.22
uniprot
proteins
function
FUNCTION: Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling. {ECO:0000250|UniProtKB:Q15131}.
uniprot
proteins
mass_dalton
40961
uniprot
proteins
protein_family
CDC2/CDKX subfamily
uniprot
proteins
protein_family
CMGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16741970
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28886341
uniprot
proteins
sequence_length
360
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q15131}.
uniprot
proteins