Btg4
entrez
56057
canonical
uniprot
O70552
canonical
ensembl
ENSMUSG00000032056
resolver
ensp
ENSMUSP00000110074
resolver
ensp
ENSMUSP00000149181
resolver
ensp
ENSMUSP00000360126
resolver
ensp
ENSMUSP00000360127
resolver
ensp
ENSMUSP00000360128
resolver
ensp
ENSMUSP00000360129
resolver
enst
ENSMUST00000114431
resolver
enst
ENSMUST00000213680
resolver
genesymbol
Btg4
resolver
genesymbol_syn
Pc3b
resolver
uniprot
Q925T9
resolver
uniprot_entry
BTG4_MOUSE
resolver
uniprot_sec
Q925T9
resolver
amino_acid_sequence
MRDEIATAVFFVTRLVKKHEKLSTQQIETFALKLMTILFEKYRGHWHPDCPSKGQAFRCIRINNNENKDPVLERACAESNVNFFHLGLPKEMTIWVDPYEVCCRYGEKKHPFTIASFKGRWENWELAQHVSCAVNRATGDCSSGTSSDEESCSREAQIIPKVNNPKSVYQVENFKQSLQPWFCLPRRKHLADGRGFLPGAACHPVPKSSKWCRPASRRVDRYHWVNAQLFSGQTAPGEPGEEALSSLKQK
uniprot
proteins
function
FUNCTION: Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E, and facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg (PubMed:27065194). It is therefore required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development (PubMed:27065194). {ECO:0000269|PubMed:27065194}.
uniprot
proteins
mass_dalton
28613
uniprot
proteins
mutagenesis
MUTAGEN 45; /note="H->A: Loss of interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 46; /note="W->A: Loss of interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 51; /note="P->A: No effect on interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 58; /note="R->A: Loss of interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 59; /note="C->A: Loss of interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 69; /note="D->A: Loss of interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 95; /note="W->A: Loss of interaction with CNOT7 and CNOT8. No effect on interaction with EIF4E."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 100; /note="E->A: No effect on interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194"; MUTAGEN 107; /note="E->A: Loss of interaction with CNOT7."; /evidence="ECO:0000269|PubMed:27065194
uniprot
proteins
protein_family
BTG family
uniprot
proteins
pubmed
10995567
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
27065194
uniprot
proteins
sequence_length
250
uniprot
proteins