Nkx6-1
entrez
65193
canonical
uniprot
O35762
canonical
ensembl
ENSRNOG00000002149
resolver
ensembl
ENSRNOG00055024791
resolver
ensembl
ENSRNOG00060010212
resolver
ensembl
ENSRNOG00065011922
resolver
ensp
ENSRNOP00000002928
resolver
ensp
ENSRNOP00055034882
resolver
ensp
ENSRNOP00060013387
resolver
ensp
ENSRNOP00065014805
resolver
enst
ENSRNOT00000002928
resolver
enst
ENSRNOT00055042722
resolver
enst
ENSRNOT00060017235
resolver
enst
ENSRNOT00065019362
resolver
genesymbol
Nkx6-1
resolver
genesymbol_syn
Nkx6.1
resolver
genesymbol_syn
Nkx6a
resolver
uniprot_entry
NKX61_RAT
resolver
amino_acid_sequence
MLAVGAMEGPRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGAHNPGGLKPPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLDPNSDDEKITQLLKKHKSSGGSLLLHASEAEGSS
uniprot
proteins
function
FUNCTION: Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity). Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q99MA9}.
uniprot
proteins
mass_dalton
37689
uniprot
proteins
pubmed
10567713
uniprot
proteins
sequence_length
365
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q99MA9}.
uniprot
proteins