Pnn
entrez
18949
canonical
uniprot
O35691
canonical
ensembl
ENSMUSG00000020994
resolver
ensp
ENSMUSP00000021381
resolver
enst
ENSMUST00000021381
resolver
genesymbol
Pnn
resolver
uniprot
F6X2B0
resolver
uniprot
Q3TUQ5
resolver
uniprot
Q8CD89
resolver
uniprot
Q8CGU3
resolver
uniprot_entry
F6X2B0_MOUSE
resolver
uniprot_entry
PININ_MOUSE
resolver
uniprot_entry
Q3TUQ5_MOUSE
resolver
uniprot_sec
Q8CD89
resolver
uniprot_sec
Q8CGU3
resolver
amino_acid_sequence
MAVAVRALQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEVEEAGEEEEKEAGIVHSDAEKEQEEEEQKQEMEVKTEEEAEVREGEKQQDSQPEEVMDVLEMVESVKHVIAEQEVMETNQVESIEPSENETSKELEPEMEFDVEPDKECKSLSPGKENINSQEVEKESEEKEEKEEKEPEPQPEPVAQPQPPPQPLPQSQPHSQPHSQPQPVLQSQPLCQPETLPLAVLQPPPQVIQEQGNLLPERKDFPLESIKLPEVSVEPVLTVHSENKSKNKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSMDRKRRDTSGLERSHKSSKGGSSRDRKGSKDKSSRPDRKRSISESSRSGKRSSRSERDRKSDRKDKRR
uniprot
proteins
function
FUNCTION: Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
82436
uniprot
proteins
protein_family
Pinin family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
9332356
uniprot
proteins
sequence_length
725
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000250}. Cell junction, desmosome {ECO:0000250}. Note=Cell-cell contact area, predominantly desmosome of intercellular adherens junction. Not a nucleocytoplasmic shuttling protein (By similarity). {ECO:0000250}.
uniprot
proteins