Plekhg3
entrez
263406
canonical
uniprot
Q4VAC9
canonical
ensembl
ENSMUSG00000052609
resolver
ensp
ENSMUSP00000074729
resolver
ensp
ENSMUSP00000151851
resolver
ensp
ENSMUSP00000321322
resolver
genesymbol
Plekhg3
resolver
genesymbol_syn
Kiaa0599
resolver
uniprot
E9QL46
resolver
uniprot
Q3TSI8
resolver
uniprot
Q6A041
resolver
uniprot
Q8BJP5
resolver
uniprot
Q8K0L5
resolver
uniprot
Q8K0T6
resolver
uniprot_entry
PKHG3_MOUSE
resolver
uniprot_sec
E9QL46
resolver
uniprot_sec
Q3TSI8
resolver
uniprot_sec
Q6A041
resolver
uniprot_sec
Q8BJP5
resolver
uniprot_sec
Q8K0L5
resolver
uniprot_sec
Q8K0T6
resolver
amino_acid_sequence
MPVSTALHQDGSQERPRSLVSTTSSSGSSRDSHSAMEEPTGSEASAQNGTGSPWDRHVPNSNNNSSGWLNMKGPLSPFNGRAGTSPAYHKLSYLGRVVREIVETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALFGNIESIYALNSQLLRDLDSCNSDPVAVASCFVERSQEFDIYTQYCNNYPNSVAALTECMQDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRVLKYHLLLQEIAKHFDEEEDGFEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEATFRVHRVRNDRTFFLFDKILLITKKRGDHFVYKGHIPCSSLMLIESTRDSLCFTVTHYKHSKQQYSIQAKTVEEKRSWTHHIKRLILENHHATIPQKAKEAILEMDSYYPSRYRCSPERMKKAWSSQDEVSSHVRQGRRQSEPGHTLFSRATLPSRQQGFEMPGLKGRRKSEPTRHLLRQLSEKARAVGMKHAGSAGALLDFGQPAHAQKQQPEAERAAREELEEEEELVEEEEQRQQSFSGSLEGLAGHDGSEKVPGPELPGSEEEEEEEESLAVAEQGKRHRESEGSKGCRRPSNRSPTSAEKRMSFESVSSLPEVETDPEPGAEQEAFAALEGPSTEEMPSDPEFPEALETQLHAPKGLLGVDNPAAVVDFVEPEGSEDLKPLSSEEEEEEEMEAAQEPESLLPPSVLDQASVIAERFASSFSRRSSLAIEDGKSSGLGTPRLISRSSSVLSLEGSDKGLARWSSIGDSLSNPPTPEVIIGADMVTDNGPSVNGTESPSAGSGCPTEQDRSSCKKKESALSTRDRQLLDKIKNYYENAEHHDAGFSIRRRESLSYIPKGLVRSSVSRFNSLPKPDSEPAAPVGYKRPGSSRPASWTLFDLPGPRTDKGDPAPITDAEFCPSSEIAKIWERMESSERSPRTGSGQSQANGFELQEPLFILEEHELGAITEESAVASPESASPTEQPSPAHLARELKELVKELSSSVQGELVTPLHPRIVQLSHVMDSHVSERVKNKVYQLARQYSLRIKNIKAARPPLQWEKVTPDQEEQVPSISGLPEEAGELSGGKARRKPVLSLLSYEQLVAQEHGTSKSSAAVETSPRRFSFSPSAVSPRTTSPGARSSARSPLSPFDTETFNWPDVRELCSKYTSHDKTAQVESSWPRSLLVNRSRSLPENIVEPPMSGKADRCCGLNTHRRLGDGEASQPPLPESPPQSQLNGGDALYVTADLTLENNQRVIIMEKGPHPSSTVGLEEDSGKESSSPVALKGQGQGFQASAEYQPKEHGPRDSADTNKQGRVRNLREKFQALNSVG
uniprot
proteins
function
FUNCTION: Plays a role in controlling cell polarity and cell motility by selectively binding newly polymerized actin and activating RAC1 and CDC42 to enhance local actin polymerization. {ECO:0000250|UniProtKB:A1L390}.
uniprot
proteins
mass_dalton
148519
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A1L390}. Note=Colocalizes with actin at the leading edge of polarized cells. {ECO:0000250|UniProtKB:A1L390}.
uniprot
proteins