Jagn1
entrez
502872
canonical
uniprot
Q4KM64
canonical
ensembl
ENSRNOG00000009175
resolver
ensembl
ENSRNOG00055008124
resolver
ensembl
ENSRNOG00060013673
resolver
ensembl
ENSRNOG00065027875
resolver
ensp
ENSRNOP00000053385
resolver
ensp
ENSRNOP00055011031
resolver
ensp
ENSRNOP00060018500
resolver
ensp
ENSRNOP00065039465
resolver
enst
ENSRNOT00000012177
resolver
enst
ENSRNOT00055013739
resolver
enst
ENSRNOT00060023335
resolver
enst
ENSRNOT00065048069
resolver
genesymbol
Jagn1
resolver
uniprot_entry
JAGN1_RAT
resolver
amino_acid_sequence
MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLLSHDQVAMPYQWEYPYLLSIVPSVLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYRFLFGFSAVSVMYLVLVLAVQVHAWQLYYSKKLLDSWFTSTQEKKRK
uniprot
proteins
function
FUNCTION: Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils. {ECO:0000250|UniProtKB:Q5XKN4, ECO:0000250|UniProtKB:Q8N5M9}.
uniprot
proteins
mass_dalton
21102
uniprot
proteins
protein_family
Jagunal family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
183
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8N5M9}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 72..92; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 97..117; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 138..158; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins