Bco2
entrez
170752
canonical
uniprot
Q99NF1
canonical
ensembl
ENSMUSG00000032066
resolver
ensp
ENSMUSP00000112727
resolver
ensp
ENSMUSP00000197299
resolver
ensp
ENSMUSP00000197303
resolver
ensp
ENSMUSP00000197304
resolver
ensp
ENSMUSP00000197305
resolver
ensp
ENSMUSP00000197307
resolver
enst
ENSMUST00000119103
resolver
genesymbol
Bco2
resolver
genesymbol_syn
Bcdo2
resolver
uniprot
Q3KNZ2
resolver
uniprot_entry
BCDO2_MOUSE
resolver
uniprot_entry
Q3KNZ2_MOUSE
resolver
amino_acid_sequence
MLGPKQSLPCIAPLLTTAEETLSAVSARVRGHIPEWLNGYLLRVGPGKFEFGKDRYNHWFDGMALLHQFRMERGTVTYKSKFLQSDTYKANSAGGRIVISEFGTLALPDPCKSIFERFMSRFEPPTMTDNTNVNFVQYKGDYYMSTETNFMNKVDIEMLERTEKVDWSKFIAVNGATAHPHYDPDGTAYNMGNSYGPRGSCYNIIRVPPKKKEPGETIHGAQVLCSIASTEKMKPSYYHSFGMTKNYIIFVEQPVKMKLWKIITSKIRGKPFADGISWEPQYNTRFHVVDKHTGQLLPGMYYSMPFLTYHQINAFEDQGCIVIDLCCQDDGRSLDLYQLQNLRKAGEGLDQVYELKAKSFPRRFVLPLDVSVDAAEGKNLSPLSYSSASAVKQGDGEIWCSPENLHHEDLEEEGGIEFPQINYGRFNGKKYSFFYGCGFRHLVGDSLIKVDVTNKTLRVWREEGFYPSEPVFVPVPGADEEDSGVILSVVITPNQSESNFLLVLDAKSFTELGRAEVPVQMPYGFHGTFVPI
uniprot
proteins
ec_number
1.13.11.-
uniprot
proteins
ec_number
1.13.11.71
uniprot
proteins
function
FUNCTION: Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids (PubMed:11278918, PubMed:21106934). Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond (PubMed:11278918, PubMed:21106934). Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules (PubMed:21106934). {ECO:0000269|PubMed:11278918, ECO:0000269|PubMed:21106934}.
uniprot
proteins
mass_dalton
60142
uniprot
proteins
protein_family
Carotenoid oxygenase family
uniprot
proteins
pubmed
11278918
uniprot
proteins
pubmed
21106934
uniprot
proteins
sequence_length
532
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:21106934}.
uniprot
proteins