Hexim2
entrez
71059
canonical
uniprot
Q3TVI4
canonical
ensembl
ENSMUSG00000043372
resolver
ensp
ENSMUSP00000053678
resolver
ensp
ENSMUSP00000102652
resolver
ensp
ENSMUSP00000265509
resolver
ensp
ENSMUSP00000265510
resolver
ensp
ENSMUSP00000265514
resolver
ensp
ENSMUSP00000265515
resolver
ensp
ENSMUSP00000265516
resolver
enst
ENSMUST00000062530
resolver
enst
ENSMUST00000107037
resolver
genesymbol
Hexim2
resolver
uniprot
Q9D4C7
resolver
uniprot_entry
HEXI2_MOUSE
resolver
uniprot_sec
Q9D4C7
resolver
amino_acid_sequence
MATVNHTNCNTASPAALEEAKTSGGLRSPQIAHEPHDFGGSQLLPSGQEIQSEDEGTVPAGDGSSCNIRGSRTQSPGGCSVEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPLAPYNTTQFLMNDRDLEEPNLDVLHGPSHSGSGGENEAGDSDGQGRAHGEFQQRDFSEAYERYHTESLQGRSKQELVRDYLDLERRLSQAEQETRRLRQLQGCSSRQPCQQVEELAAEVERLRTENQRLRQENEMWNREGGYCDQEKPASEGTPWPKVEAPFQTHTGQLGHREAGDR
uniprot
proteins
function
FUNCTION: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. {ECO:0000250|UniProtKB:Q96MH2}.
uniprot
proteins
mass_dalton
35397
uniprot
proteins
protein_family
HEXIM family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
313
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q96MH2}.
uniprot
proteins