Cenpi
entrez
102920
canonical
uniprot
Q8K1K4
canonical
ensembl
ENSMUSG00000031262
resolver
ensp
ENSMUSP00000079851
resolver
ensp
ENSMUSP00000098809
resolver
ensp
ENSMUSP00000277994
resolver
ensp
ENSMUSP00000277996
resolver
enst
ENSMUST00000081064
resolver
enst
ENSMUST00000101251
resolver
genesymbol
Cenpi
resolver
genesymbol_syn
Fshprh1
resolver
uniprot
Q3TTB0
resolver
uniprot
Q8BXU9
resolver
uniprot_entry
CENPI_MOUSE
resolver
uniprot_entry
Q3TTB0_MOUSE
resolver
uniprot_sec
Q8BXU9
resolver
amino_acid_sequence
MATQRVTRNSQQQNRISQGSNSRQTSLLDWMVKDKSGNFKSVLKESSSVEDSTRTDDRTEGALQVAVGYFQKGPKKASLSKDKVLEKHLTTVENVALSNGLAPEAIDILLNVALSGKFGNAVNSRILKCMIPESHISEDSVLKAVSWLCVDKCSGNTKVLFYRWLVAMFDFIDHKKQISSLYGFFFASLQDDTLCPYVCHLLYLLTKRENVKPFRVRKLLDLQAKMGMQPHLQALLSLYKFFAPTLISVSLPVRKKIFFNNSKNLWTSASLAVRLRNQGAFPEPLNLPLRPTTGRSLKRKWNSHSVIPALNSANKEYGEKTASLFDYLSSERSLPLEQLQRFPQLLESIHCLELPSQMCSVLNSPLLLHYINCVKDESILLRISYWLSQALQEECVWYNINNYEQEKEFINFLDLVIRVQCFLQEGFYSCEAFLYKSLPLWDGSSCRSQYLQLLAWIPFSSFSEVKPLLSDHLAPLFFTSSIYFKCSVLQSLQELLQNWLLWLSTDAHVQPTTDSPLETTLGGSMSSVSQLIEYTGWLCVVAMRLESSSTLLLHFILDFYEKVCDIYINYDLPIVVLFPPVIFHSALLSLDATILNQLCYIMYRYRNNWTAAKKNRYLQKAKPEFSLSSKICKEYNYYLTAMVCCLWTSRPFKAGVYTDPETIENTGGTQYKSTLNIVYHPSLLSYAASFLLQESPEEMTEHLSSIQGKKWNWYLDYLYSEGFQGLKLFIKSSVHSSVPKPEENTE
uniprot
proteins
function
FUNCTION: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
85403
uniprot
proteins
post_translational_modification
PTM: Sumoylated. Sumoylated form can be polyubiquitinated by RNF4, leading to its degradation. Desumoylation by SENP6 prevents its degradation (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
CENP-I/CTF3 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
746
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere {ECO:0000250}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex (By similarity). {ECO:0000250}.
uniprot
proteins