Scamp5
entrez
56807
canonical
uniprot
Q9JKD3
canonical
ensembl
ENSMUSG00000040722
resolver
ensp
ENSMUSP00000035898
resolver
ensp
ENSMUSP00000150867
resolver
ensp
ENSMUSP00000335613
resolver
enst
ENSMUST00000046587
resolver
enst
ENSMUST00000214256
resolver
genesymbol
Scamp5
resolver
uniprot_entry
SCAM5_MOUSE
resolver
amino_acid_sequence
MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM
uniprot
proteins
function
FUNCTION: Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
26068
uniprot
proteins
protein_family
SCAMP family
uniprot
proteins
protein_family
SCAMP5 subfamily
uniprot
proteins
pubmed
11050114
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
235
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11050114}; Multi-pass membrane protein {ECO:0000269|PubMed:11050114}. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Recycling endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:11050114}; Multi-pass membrane protein {ECO:0000269|PubMed:11050114}. Note=Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..125; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 149..169; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins