F13B
entrez
2165
canonical
uniprot
P05160
canonical
ensembl
ENSG00000143278
resolver
ensembl
ENSG00000291998
resolver
ensp
ENSP00000356382
resolver
ensp
ENSP00000517743
resolver
ensp
ENSP00000774070
resolver
enst
ENST00000367412
resolver
enst
ENST00000709526
resolver
genesymbol
F13B
resolver
hgnc
HGNC:3534
resolver
uniprot
A8K3E5
resolver
uniprot
Q5VYL5
resolver
uniprot_entry
F13B_HUMAN
resolver
uniprot_sec
A8K3E5
resolver
uniprot_sec
Q5VYL5
resolver
amino_acid_sequence
MRLKNLTFIIILIISGELYAEEKPCGFPHVENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEGWSPEPRCFKKCTKPDLSNGYISDVKLLYKIQENMRYGCASGYKTTGGKDEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYGWSLTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFGWYPESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGKWTEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGKWTLPPECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLDGMWTTPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFICRGDTYPAELYITGSILRMQCDRGQLKYPRCIPRQSTLSYQEPLRT
uniprot
proteins
disease_involvement
DISEASE: Factor XIII subunit B deficiency (FA13BD) [MIM:613235]: An autosomal recessive hematologic disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women. {ECO:0000269|PubMed:11313256, ECO:0000269|PubMed:20331752, ECO:0000269|PubMed:26247044, ECO:0000269|PubMed:8324218}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. {ECO:0000303|PubMed:21742792, ECO:0000303|PubMed:3021194}.
uniprot
proteins
mass_dalton
75511
uniprot
proteins
pubmed
10391209
uniprot
proteins
pubmed
11313256
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
20331752
uniprot
proteins
pubmed
21742792
uniprot
proteins
pubmed
2271707
uniprot
proteins
pubmed
2339067
uniprot
proteins
pubmed
26247044
uniprot
proteins
pubmed
3021194
uniprot
proteins
pubmed
4405643
uniprot
proteins
pubmed
8324218
uniprot
proteins
sequence_length
661
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26247044, ECO:0000269|PubMed:4405643}.
uniprot
proteins