Q0WX57
uniprot
Q0WX57
canonical
amino_acid_sequence
MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ
uniprot
proteins
ec_number
3.4.19.12
uniprot
proteins
function
FUNCTION: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection. {ECO:0000269|PubMed:10936051}.
uniprot
proteins
mass_dalton
59711
uniprot
proteins
mutagenesis
MUTAGEN 89; /note="C->S: Abolishes enzymatic activity. Loss of the pro-apoptotic function."; /evidence="ECO:0000269|PubMed:10936051, ECO:0000269|PubMed:17109758
uniprot
proteins
protein_family
Peptidase C19 family
uniprot
proteins
protein_family
USP17 subfamily
uniprot
proteins
pubmed
10936051
uniprot
proteins
pubmed
11941478
uniprot
proteins
pubmed
15780755
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17109758
uniprot
proteins
pubmed
20403174
uniprot
proteins
sequence_length
530
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:17109758}. Endoplasmic reticulum {ECO:0000250}.
uniprot
proteins