Arhgdig
entrez
14570
canonical
uniprot
Q62160
canonical
ensembl
ENSMUSG00000073433
resolver
ensp
ENSMUSP00000025019
resolver
enst
ENSMUST00000025019
resolver
genesymbol
Arhgdig
resolver
genesymbol_syn
Gdi5
resolver
uniprot
Q3UNB6
resolver
uniprot_entry
GDIR3_MOUSE
resolver
uniprot_entry
Q3UNB6_MOUSE
resolver
amino_acid_sequence
MLGLDACELGEQLLELLRLALCARVLLADKDGESTPSDEVLDEIVPEYQAPGKKSMLAIWQLDPGDVSLVKYKQALLGPLPPIMDPSLPNVQVTRLTLLTEQAPGPIIMDLTGDLDALKNQVFVLKEGIEYKVKITFKVNKEIVSGLKCLHHTYRRGLRVDKAIFMVGSYGPRAQEYEFVTSVEEAPRGALARGLYVVRSLFTDDDRLNHLSWEWHLHVCQDWKD
uniprot
proteins
function
FUNCTION: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
uniprot
proteins
mass_dalton
25296
uniprot
proteins
protein_family
Rho GDI family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8939998
uniprot
proteins
sequence_length
225
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins