SDC3
entrez
9672
canonical
uniprot
O75056
canonical
ensembl
ENSG00000162512
resolver
ensp
ENSP00000344468
resolver
enst
ENST00000339394
resolver
genesymbol
SDC3
resolver
genesymbol_syn
KIAA0468
resolver
hgnc
HGNC:10660
resolver
uniprot
Q5T1Z6
resolver
uniprot
Q5T1Z7
resolver
uniprot
Q96CT3
resolver
uniprot
Q96PR8
resolver
uniprot_entry
SDC3_HUMAN
resolver
uniprot_sec
Q5T1Z6
resolver
uniprot_sec
Q5T1Z7
resolver
uniprot_sec
Q96CT3
resolver
uniprot_sec
Q96PR8
resolver
amino_acid_sequence
MKPGPPHRAGAAHGAGAGAGAAAGPGARGLLLPPLLLLLLAGRAAGAQRWRSENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGIETAMRFSPDVALAVSTTPAVLPTTNIQPVGTPFEELPSERPTLEPATSPLVVTEVPEEPSQRATTVSTTMATTAATSTGDPTVATVPATVATATPSTPAAPPFTATTAVIRTTGVRRLLPLPLTTVATARATTPEAPSPPTTAAVLDTEAPTPRLVSTATSRPRALPRPATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELPEEETTQPDTANEVVAVGGAAAKASSPPGTLPKGARPGPGLLDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQEEFYA
uniprot
proteins
function
FUNCTION: Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. {ECO:0000250, ECO:0000269|PubMed:11527150}.
uniprot
proteins
mass_dalton
45497
uniprot
proteins
post_translational_modification
PTM: O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules. {ECO:0000305}.
uniprot
proteins
protein_family
Syndecan proteoglycan family
uniprot
proteins
pubmed
11527150
uniprot
proteins
pubmed
12407114
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
23395182
uniprot
proteins
pubmed
9388509
uniprot
proteins
pubmed
9455484
uniprot
proteins
sequence_length
442
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 388..408; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins