LTBR
entrez
4055
canonical
uniprot
P36941
canonical
ensembl
ENSG00000111321
resolver
ensp
ENSP00000228918
resolver
ensp
ENSP00000440875
resolver
ensp
ENSP00000554103
resolver
ensp
ENSP00000554104
resolver
ensp
ENSP00000554105
resolver
ensp
ENSP00000627688
resolver
ensp
ENSP00000627691
resolver
ensp
ENSP00000627693
resolver
ensp
ENSP00000665706
resolver
genesymbol
LTBR
resolver
genesymbol_syn
D12S370
resolver
genesymbol_syn
TNFCR
resolver
genesymbol_syn
TNFR3
resolver
genesymbol_syn
TNFRSF3
resolver
hgnc
HGNC:6718
resolver
uniprot
B7Z1D2
resolver
uniprot
D3DUR2
resolver
uniprot
F5GXE7
resolver
uniprot_entry
TNR3_HUMAN
resolver
uniprot_sec
B7Z1D2
resolver
uniprot_sec
D3DUR2
resolver
uniprot_sec
F5GXE7
resolver
amino_acid_sequence
MLLPWATSAPGLAWGPLVLGLFGLLAASQPQAVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTMLMLAVLLPLAFFLLLATVFSCIWKSHPSLCRKLGSLLKRRPQGEGPNPVAGSWEPPKAHPYFPDLVQPLLPISGDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHVTGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAWHLAETEHCGATPSNRGPRNQFITHD
uniprot
proteins
function
FUNCTION: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT (PubMed:24248355). Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)) (PubMed:24248355). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. {ECO:0000269|PubMed:10799510, ECO:0000269|PubMed:24248355, ECO:0000269|PubMed:8171323}.
uniprot
proteins
mass_dalton
46709
uniprot
proteins
mutagenesis
MUTAGEN 40; /note="N->G: Does not affect interaction with Aedes aegypti lymphotoxin beta receptor inhibitor."; /evidence="ECO:0000269|PubMed:38248473"; MUTAGEN 177; /note="N->G: Does not affect interaction with A.aegypti lymphotoxin beta receptor inhibitor."; /evidence="ECO:0000269|PubMed:38248473
uniprot
proteins
pubmed
10207006
uniprot
proteins
pubmed
10799510
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
24248355
uniprot
proteins
pubmed
29507355
uniprot
proteins
pubmed
38248473
uniprot
proteins
pubmed
8171323
uniprot
proteins
pubmed
8486360
uniprot
proteins
pubmed
8663299
uniprot
proteins
pubmed
8995654
uniprot
proteins
pubmed
9511754
uniprot
proteins
pubmed
9626059
uniprot
proteins
sequence_length
435
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 228..248; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins