Atg9b
entrez
213948
canonical
uniprot
Q6EBV9
canonical
ensembl
ENSMUSG00000038295
resolver
ensp
ENSMUSP00000051864
resolver
enst
ENSMUST00000059401
resolver
genesymbol
Atg9b
resolver
genesymbol_syn
Apg9l2
resolver
genesymbol_syn
Nos3as
resolver
uniprot
F8VQL8
resolver
uniprot
Q674R6
resolver
uniprot_entry
ATG9B_MOUSE
resolver
uniprot_sec
F8VQL8
resolver
uniprot_sec
Q674R6
resolver
amino_acid_sequence
MVRRTGWGGSRRQRGRWGDLGPSSVPLLPMALPLPASPCRGTGGRRISVFSLSPAPRTRSCSSSVFPPASGSPCLVIQEAGASQTPHNVLPTPTTPSTQAHPTMIHTSASPSWGSHSTPPLASATPPPSCPRPQDHPGLRMGPLIPEQDYERLEDCDPEGSQDSPIHGEDHQPLLHVPEGLRGSWHHIQNLDSFFTKIYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFNNQPKNHTRRGPLHSKVTLSDAILPSAQCAEKIHDSPLLVFLLVLAAGFWLFQLLRSVCNLFSYWDIQVFYREALHIPPEELSSVPWAEVQSRLLELQRSGGLCVQPRPLTELDVHHRILRYTNYQVALANKGLLPARCPLPWGSSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPEAYKRSDLRGVLANRWRRTVLLLAAVNLALSPLVLAWQVLHAFYSHVELLRREPGAFGARRWSRLARLQLRHFNELPHELRARLGRAYRPAAAFLRAAEPPAPLRALLARQLVFFSGALFAALLVLTIYDEDVLAVEHVLTTMTALGVTATVARSFIPEEQCQGRSSQLLLQAALAHMHYLPEEPGATGARASSYWQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHFTVDVAGVGDICSFALMDVKRHGHPQWLSEGQTEASLSQRAEDGKTELSLMRFSLAHPQWQPPGHSSKFLGHLRGRVQQDAAAWGAPSTRSPPTPGVLSDCTSPLPEAFLANLLVNPRPPQRDLSPTAPCPAAATASLLASISRMVQDPSCVSPGGTGGQKLTQLPELVSAEMSLHAIYLHQLHQQQQQELWGEASASSPSRPWSSPSQPGSPDEEKPSWSSDGSSPASSPRQQWGTQRAQNLFPKGFQENTDTQKEPLTGPLH
uniprot
proteins
function
FUNCTION: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion (PubMed:15755735). Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity). In addition to autophagy, also plays a role in necrotic cell death (By similarity). {ECO:0000250|UniProtKB:Q68FE2, ECO:0000250|UniProtKB:Q7Z3C6, ECO:0000269|PubMed:15755735}.
uniprot
proteins
mass_dalton
101913
uniprot
proteins
protein_family
ATG9 family
uniprot
proteins
pubmed
15234981
uniprot
proteins
pubmed
15755735
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
922
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Preautophagosomal structure membrane {ECO:0000269|PubMed:15755735}; Multi-pass membrane protein {ECO:0000269|PubMed:15755735}. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1 and ATG13. {ECO:0000250|UniProtKB:Q674R7}.
uniprot
proteins
transmembrane_region
TRANSMEM 207..227; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 276..296; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 524..544; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 551..571; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins