Lias
entrez
305348
canonical
uniprot
Q5XIH4
canonical
ensembl
ENSRNOG00000002759
resolver
ensembl
ENSRNOG00055017981
resolver
ensembl
ENSRNOG00060015945
resolver
ensembl
ENSRNOG00065013434
resolver
ensp
ENSRNOP00000003779
resolver
ensp
ENSRNOP00055024511
resolver
ensp
ENSRNOP00060021910
resolver
ensp
ENSRNOP00065017132
resolver
enst
ENSRNOT00000003779
resolver
enst
ENSRNOT00055030457
resolver
enst
ENSRNOT00060027312
resolver
enst
ENSRNOT00065022100
resolver
genesymbol
Lias
resolver
uniprot_entry
LIAS_RAT
resolver
amino_acid_sequence
MALRCWDAARSLGSRIFGRYACSVRALSSLPDEKKKFLHNGPDLQDFVSGDLADKSTWDDYKGNLKRQKGERLRLPPWLKTKIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDPSEPDNTARAIAEWGLDYVVLTSVDRDDVVDGGAEHIAKTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRANFDQSLRVLKHAKEVQPDVVSKTSIMLGLGETDEQVYATMKALRAADVDCLTLGQYMQPTKRHLKVEEYVTPEKFKYWEEVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRKTKVSKV
uniprot
proteins
ec_number
2.8.1.8
uniprot
proteins
function
FUNCTION: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}.
uniprot
proteins
mass_dalton
41874
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2. {ECO:0000255|HAMAP-Rule:MF_03123}.
uniprot
proteins
protein_family
Lipoyl synthase family
uniprot
proteins
protein_family
Radical SAM superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03123}.
uniprot
proteins