Gipr
entrez
381853
canonical
uniprot
Q0P543
canonical
ensembl
ENSMUSG00000030406
resolver
ensp
ENSMUSP00000092384
resolver
genesymbol
Gipr
resolver
uniprot
Q80UB4
resolver
uniprot_entry
GIPR_MOUSE
resolver
uniprot_sec
Q80UB4
resolver
amino_acid_sequence
MPLRLLLLLLWLWGLQWAETDSEGQTTTGELYQRWEHYGQECQKMLETTEPPSGLACNGSFDMYACWNYTAANTTARVSCPWYLPWFRQVSAGFVFRQCGSDGQWGSWRDHTQCENPEKNGAFQDQTLILERLQIMYTVGYSLSLTTLLLALLILSLFRRLHCTRNYIHMNLFTSFMLRAAAILTRDQLLPPLGPYTGDQAPTPWNQALAACRTAQIMTQYCVGANYTWLLVEGVYLHHLLVIVGRSEKGHFRCYLLLGWGAPALFVIPWVIVRYLRENTQCWERNEVKAIWWIIRTPILITILINFLIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQVEGSLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRQGWRHRRLRLSLQEQRPRPHQELAPRAVPLSSACREAAVGNALPSGMLHVPGDEVLESYC
uniprot
proteins
function
FUNCTION: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. {ECO:0000250|UniProtKB:P48546}.
uniprot
proteins
mass_dalton
52992
uniprot
proteins
post_translational_modification
PTM: N-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER. {ECO:0000250|UniProtKB:P48546}.
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
12679517
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
31905038
uniprot
proteins
sequence_length
460
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 135..155; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 167..185; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 223..243; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 256..276; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 298..318; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 338..358; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 371..391; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins