ARTN
entrez
9048
canonical
uniprot
Q5T4W7
canonical
ensembl
ENSG00000117407
resolver
ensp
ENSP00000361429
resolver
ensp
ENSP00000361434
resolver
ensp
ENSP00000387435
resolver
ensp
ENSP00000436727
resolver
ensp
ENSP00000633470
resolver
genesymbol
ARTN
resolver
genesymbol_syn
EVN
resolver
hgnc
HGNC:727
resolver
uniprot
D3DPY1
resolver
uniprot
D3DPY3
resolver
uniprot
O95441
resolver
uniprot
O96030
resolver
uniprot
Q6P6A3
resolver
uniprot_entry
ARTN_HUMAN
resolver
uniprot_sec
D3DPY1
resolver
uniprot_sec
D3DPY3
resolver
uniprot_sec
O95441
resolver
uniprot_sec
O96030
resolver
uniprot_sec
Q6P6A3
resolver
amino_acid_sequence
MELGLGGLSTLSHCPWPRQQPALWPTLAALALLSSVAEASLGSAPRSPAPREGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPAPPPPAPPSALPRGGRAARAGGPGSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCLG
uniprot
proteins
function
FUNCTION: Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain (PubMed:10583383, PubMed:9883723). Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor (PubMed:31535977). Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue (By similarity). {ECO:0000250|UniProtKB:Q9Z0L2, ECO:0000269|PubMed:10583383, ECO:0000269|PubMed:31535977, ECO:0000269|PubMed:9883723}.
uniprot
proteins
mass_dalton
22878
uniprot
proteins
protein_family
GDNF subfamily
uniprot
proteins
protein_family
TGF-beta family
uniprot
proteins
pubmed
10583383
uniprot
proteins
pubmed
10673327
uniprot
proteins
pubmed
15204970
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16765900
uniprot
proteins
pubmed
31535977
uniprot
proteins
pubmed
9883723
uniprot
proteins
sequence_length
220
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15204970}.
uniprot
proteins