CFAP126
entrez
257177
canonical
uniprot
Q5VTH2
canonical
ensembl
ENSG00000188931
resolver
ensp
ENSP00000356951
resolver
enst
ENST00000367974
resolver
genesymbol
CFAP126
resolver
genesymbol_syn
C1orf192
resolver
genesymbol_syn
FLTP
resolver
hgnc
HGNC:32325
resolver
uniprot_entry
FLTOP_HUMAN
resolver
amino_acid_sequence
MATNYSANQYEKAFSSKYLQNWSPTKPTKESISSHEGYTQIIANDRGHLLPSVPRSKANPWGSFMGTWQMPLKIPPARVTLTSRTTAGAASLTKWIQKNPDLLKASNGLCPEILGKPHDPDSQKKLRKKSITKTVQQARSPTIIPSSPAANLNSPDELQSSHPSAGHTPGPQRPAKS
uniprot
proteins
function
FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme (PubMed:36191189). Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells (By similarity). Regulates basal body docking and cilia formation in multiciliated lung cells (By similarity). Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear (By similarity). {ECO:0000250|UniProtKB:Q6P8X9, ECO:0000269|PubMed:36191189}.
uniprot
proteins
mass_dalton
19293
uniprot
proteins
protein_family
Flattop family
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
36191189
uniprot
proteins
pubmed
8889548
uniprot
proteins
sequence_length
177
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q6P8X9}. Cell projection, cilium {ECO:0000250|UniProtKB:Q6P8X9}. Apical cell membrane {ECO:0000250|UniProtKB:Q6P8X9}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:36191189}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q6P8X9}. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells (By similarity). {ECO:0000250|UniProtKB:Q3SZT6, ECO:0000250|UniProtKB:Q6P8X9}.
uniprot
proteins