Marco
entrez
17167
canonical
uniprot
Q60754
canonical
ensembl
ENSMUSG00000026390
resolver
ensp
ENSMUSP00000027639
resolver
enst
ENSMUST00000027639
resolver
genesymbol
Marco
resolver
uniprot
A2RT24
resolver
uniprot_entry
A2RT24_MOUSE
resolver
uniprot_entry
MARCO_MOUSE
resolver
amino_acid_sequence
MGSKELLKEEDFLGSTEDRADFDQAMFPVMETFEINDPVPKKRNGGTFCMAVMAIHLILLTAGTALLLIQVLNLQEQLQMLEMCCGNGSLAIEDKPFFSLQWAPKTHLVPRAQGLQALQAQLSWVHTSQEQLRQQFNNLTQNPELFQIKGERGSPGPKGAPGAPGIPGLPGPAAEKGEKGAAGRDGTPGVQGPQGPPGSKGEAGLQGLTGAPGKQGATGAPGPRGEKGSKGDIGLTGPKGEHGTKGDKGDLGLPGNKGDMGMKGDTGPMGSPGAQGGKGDAGKPGLPGLAGSPGVKGDQGKPGVQGVPGPQGAPGLSGAKGEPGRTGLPGPAGPPGIAGNPGIAGVKGSKGDTGIQGQKGTKGESGVPGLVGRKGDTGSPGLAGPKGEPGRVGQKGDPGMKGSSGQQGQKGEKGQKGESFQRVRIMGGTNRGRAEVYYNNEWGTICDDDWDNNDATVFCRMLGYSRGRALSSYGGGSGNIWLDNVNCRGTENSLWDCSKNSWGNHNCVHNEDAGVECS
uniprot
proteins
function
FUNCTION: Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:7867067). Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 (By similarity). {ECO:0000250|UniProtKB:Q9UEW3, ECO:0000250|UniProtKB:Q9WUB9, ECO:0000269|PubMed:7867067}.
uniprot
proteins
mass_dalton
52730
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:7867067}.
uniprot
proteins
pubmed
10331948
uniprot
proteins
pubmed
17405873
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7867067
uniprot
proteins
sequence_length
518
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:7867067}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 49..69; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins