Tekt5
entrez
70426
canonical
uniprot
G5E8A8
canonical
ensembl
ENSMUSG00000039179
resolver
ensp
ENSMUSP00000046824
resolver
genesymbol
Tekt5
resolver
uniprot
D5HP88
resolver
uniprot
Q14BE9
resolver
uniprot_entry
TEKT5_MOUSE
resolver
uniprot_sec
D5HP88
resolver
uniprot_sec
Q14BE9
resolver
amino_acid_sequence
MEFLGTTQTASFCGPKKGCGLQALPPAGQEPVVQECYQPFHLPGYRYLNAWRPSVFHKIATSQTIPEECSGIRRPPTILPSLRSALFCRYTPRDWDRSNDLQIRNAEASRLWASRLTGDSLRIMQDKDQLIHQMQEGTSRNLGQRLSDLGFWKSELCYELDRLLTENSSMDTLKRRLECAAEEVNCPLQVALECLYNREKRIGIDLVHDNVEKNLIREVDLLKCCQDQMRKLAKRIDFQIRDNRDAQHSLERDIEDKSSAQYIDENCFNLRSTSDSISFFHGVEKFDGTVSIPETWAKFSNDNIRHAQNMRANSIRLREEAEHLFETLSDQMWKQFTNTNLAFNARISEETDVKNKLQTQLAKILQEIFQAENTIMLLERAIVAKEYPLKMAQTMLACRTRRPNVELCRDVPQFRLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKSRLEHELAIKANTLCIDKDKCMSMRKSFPSTPRLTGYTCSAIGSGPYANHAPRISSGPCSGSALCKGPASCGGGASCGGGASCGGHAPCGSALCSHSVSRSGPGFAPVC
uniprot
proteins
function
FUNCTION: Sperm-specific microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in flagellar axoneme (PubMed:20378928, PubMed:37295417, PubMed:37865089, PubMed:37989994). Forms an extensive interaction network in different conformations that reinforces the helix bundle composed by other tektin proteins (TEKT1 to TEKT4) and MIPs to anchor the tektin bundle onto the tubulin wall of A-tubule of the sperm flagellum (PubMed:37295417, PubMed:37865089). {ECO:0000269|PubMed:20378928, ECO:0000269|PubMed:37295417, ECO:0000269|PubMed:37865089, ECO:0000269|PubMed:37989994}.
uniprot
proteins
mass_dalton
62734
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. {ECO:0000269|PubMed:36206347}.
uniprot
proteins
protein_family
Tektin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20378928
uniprot
proteins
pubmed
36206347
uniprot
proteins
pubmed
36708031
uniprot
proteins
pubmed
37295417
uniprot
proteins
pubmed
37865089
uniprot
proteins
pubmed
37989994
uniprot
proteins
sequence_length
557
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37295417, ECO:0000269|PubMed:37865089, ECO:0000269|PubMed:37989994, ECO:0000305|PubMed:20378928}.
uniprot
proteins