Tsen34
entrez
66078
canonical
uniprot
Q8BMZ5
canonical
ensembl
ENSMUSG00000035585
resolver
ensp
ENSMUSP00000046911
resolver
ensp
ENSMUSP00000104267
resolver
ensp
ENSMUSP00000104269
resolver
ensp
ENSMUSP00000104270
resolver
ensp
ENSMUSP00000145965
resolver
ensp
ENSMUSP00000188816
resolver
ensp
ENSMUSP00000188822
resolver
ensp
ENSMUSP00000188824
resolver
ensp
ENSMUSP00000188825
resolver
ensp
ENSMUSP00000188827
resolver
ensp
ENSMUSP00000188828
resolver
ensp
ENSMUSP00000188829
resolver
ensp
ENSMUSP00000343724
resolver
enst
ENSMUST00000038521
resolver
enst
ENSMUST00000205287
resolver
genesymbol
Tsen34
resolver
genesymbol_syn
Leng5
resolver
genesymbol_syn
Sen34
resolver
uniprot
A0A0U1RPF7
resolver
uniprot
H7BX14
resolver
uniprot
Q58EU2
resolver
uniprot
Q99LV6
resolver
uniprot
Q9CWG3
resolver
uniprot
Q9CYW1
resolver
uniprot_entry
A0A0U1RPF7_MOUSE
resolver
uniprot_entry
H7BX14_MOUSE
resolver
uniprot_entry
Q9CWG3_MOUSE
resolver
uniprot_entry
SEN34_MOUSE
resolver
uniprot_sec
Q58EU2
resolver
uniprot_sec
Q99LV6
resolver
uniprot_sec
Q9CYW1
resolver
amino_acid_sequence
MLVVEVANGRSLVWGAEAVQALRERLGVGGRTVGALPRGPRQNSRLGLPLLLLPEEARLLAEIGAVTLVSAPRPDPRNHGLALASFKRQQEQSFQDQNTLAAEARETRRQELLEKIVEGQAAKKQKLEQDSGADEGGQEAGGSEATQGSETSDDGQPSAEQEGAAPSLDSSSPQPGPSNGVTPLPRSALLIQLATARPRPVKAKPLDWRVQSKDWPHAGRPAHELRYSIYRDLWERGFFLSAAGKFGGDFLVYPGDPLRFHAHYIAQCWSAEDPIPLQDLVSAGRLGTSVRKTLLLCSPQPDGKVVYTSLQWASLQ
uniprot
proteins
ec_number
4.6.1.16
uniprot
proteins
function
FUNCTION: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
34196
uniprot
proteins
protein_family
TRNA-intron endonuclease family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
316
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=May be transiently localized in the nucleolus. {ECO:0000250}.
uniprot
proteins