HIGD1A
entrez
25994
canonical
uniprot
Q9Y241
canonical
ensembl
ENSG00000181061
resolver
ensp
ENSP00000319393
resolver
ensp
ENSP00000398064
resolver
ensp
ENSP00000402160
resolver
genesymbol
HIGD1A
resolver
genesymbol_syn
HIG1
resolver
hgnc
HGNC:29527
resolver
uniprot
Q9UFZ2
resolver
uniprot_entry
HIG1A_HUMAN
resolver
uniprot_sec
Q9UFZ2
resolver
amino_acid_sequence
MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP
uniprot
proteins
function
FUNCTION: Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes. {ECO:0000269|PubMed:22342701}.
uniprot
proteins
mass_dalton
10143
uniprot
proteins
pubmed
10690527
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22342701
uniprot
proteins
pubmed
22609626
uniprot
proteins
sequence_length
93
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-ProRule:PRU00836, ECO:0000269|PubMed:22342701}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00836, ECO:0000269|PubMed:22342701}. Mitochondrion inner membrane {ECO:0000305|PubMed:22342701}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..46; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"; TRANSMEM 60..80; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00836
uniprot
proteins