Cav3
entrez
29161
canonical
uniprot
P51638
canonical
ensembl
ENSRNOG00000005798
resolver
ensembl
ENSRNOG00055006838
resolver
ensembl
ENSRNOG00060012913
resolver
ensembl
ENSRNOG00065027134
resolver
ensp
ENSRNOP00000007601
resolver
ensp
ENSRNOP00055008802
resolver
ensp
ENSRNOP00060017389
resolver
ensp
ENSRNOP00065038345
resolver
enst
ENSRNOT00000007601
resolver
enst
ENSRNOT00055011228
resolver
enst
ENSRNOT00060021972
resolver
enst
ENSRNOT00065046767
resolver
genesymbol
Cav3
resolver
uniprot_entry
CAV3_RAT
resolver
amino_acid_sequence
MMTEEHTDLEARIIKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPEGTYSFDGVWRVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSNIKVVLRREG
uniprot
proteins
function
FUNCTION: May act as a scaffolding protein within caveolar membranes. Interacts directly with G protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. {ECO:0000250|UniProtKB:P51637, ECO:0000250|UniProtKB:P56539}.
uniprot
proteins
mass_dalton
17402
uniprot
proteins
post_translational_modification
PTM: Sumoylation with SUMO3 by PIAS4 may reduce agonist-induced internalization and desensitization of adrenergic receptor ABRD2. {ECO:0000250}.
uniprot
proteins
protein_family
Caveolin family
uniprot
proteins
pubmed
15277200
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24567387
uniprot
proteins
pubmed
26497963
uniprot
proteins
pubmed
8567687
uniprot
proteins
sequence_length
151
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:24567387, ECO:0000269|PubMed:26497963}; Peripheral membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250|UniProtKB:P51637}; Peripheral membrane protein {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P51637}. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). {ECO:0000250}.
uniprot
proteins