Fbxw18
entrez
546161
canonical
uniprot
Q3TSA9
canonical
ensembl
ENSMUSG00000074059
resolver
ensp
ENSMUSP00000095962
resolver
enst
ENSMUST00000098359
resolver
genesymbol
Fbxw18
resolver
genesymbol_syn
C85627
resolver
uniprot
F6SKL6
resolver
uniprot_entry
F6SKL6_MOUSE
resolver
uniprot_entry
Q3TSA9_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: In oocytes and preimplantation embryos, SCF(Fbxw18) ubiquitin ligase complex is maintained inactive by cytoplasmic lattices. {ECO:0000269|PubMed:41917274}.
uniprot
proteins
amino_acid_sequence
METHLPSLPSLPMMKILSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLYCDTVILQLHDKETWKQFFVNRTYQEHTKTRAKPEDFTYKEICAETGIWAYACYISGRGLTRNGQGTSVVCMLTSMTKISTWDIHEGVMTWVSPVQPTTIKLLNTLPEMHIAVTVDIHSTIKLWDCNSSDALATNNLFFPCQTLKSVFTKDAAIVLVSDTLGNLYIFRIPDLHLISTINVFPYGINELYCSPQKKWVFLSRKHPHILPKVFYMNSLLRRSEFSAPVSTVLNFSLCDKAFWTPRKEDRITLMSISAPYKVTKFVTFDMKLEEIGNQIIVTGYLIASFSLTDYEGRLECFGVSDKDVIVCSTGSSLLLFSIYGVCLQTFDYCSEEILRLWVDPFHVIVTFIDGSLDVYAWEERCQQLSKCYRLQNRRRLPRQSCFEKTLCDEVSIIRMVRNGRNPCYLMTYTLNIHS
uniprot
proteins
function
FUNCTION: Substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, which mediates ubiquitination and degradation of target proteins. {ECO:0000250|UniProtKB:E9PXM9}.
uniprot
proteins
mass_dalton
54146
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:E9PXM9}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
41917274
uniprot
proteins
sequence_length
469
uniprot
proteins