SYT8
entrez
90019
canonical
uniprot
Q8NBV8
canonical
ensembl
ENSG00000149043
resolver
ensembl
ENSG00000288149
resolver
ensp
ENSP00000343691
resolver
ensp
ENSP00000371394
resolver
ensp
ENSP00000371406
resolver
ensp
ENSP00000523036
resolver
genesymbol
SYT8
resolver
hgnc
HGNC:19264
resolver
uniprot
A6NCR4
resolver
uniprot
A6NFJ4
resolver
uniprot
Q9NSV9
resolver
uniprot_entry
SYT8_HUMAN
resolver
uniprot_sec
A6NCR4
resolver
uniprot_sec
A6NFJ4
resolver
uniprot_sec
Q9NSV9
resolver
amino_acid_sequence
MGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGCLQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS
uniprot
proteins
function
FUNCTION: Involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in insulin secreted cells. {ECO:0000250|UniProtKB:Q9R0N6}.
uniprot
proteins
mass_dalton
42433
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
387
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9R0N6}.
uniprot
proteins
transmembrane_region
TRANSMEM 35..55; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins