Mthfd2l
entrez
665563
canonical
uniprot
D3YZG8
canonical
ensembl
ENSMUSG00000029376
resolver
ensp
ENSMUSP00000071578
resolver
ensp
ENSMUSP00000298576
resolver
ensp
ENSMUSP00000298580
resolver
ensp
ENSMUSP00000298581
resolver
enst
ENSMUST00000071652
resolver
genesymbol
Mthfd2l
resolver
uniprot_entry
MTD2L_MOUSE
resolver
amino_acid_sequence
MATRARGFSLLRGRLGRGPVRAPGVAERAWRGFGSSGRRHEAVIISGTNMAKQIQKEIQQGVESWIALGNRRPHLSIILVGDNPASHTYVRNKIKAASAVGICSELIIKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRAGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPREQLKAHTQLADIIIVAAGIPRLITADMVREGAAVIDVGINYIQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNIAY
uniprot
proteins
ec_number
1.5.1.15
uniprot
proteins
ec_number
1.5.1.5
uniprot
proteins
ec_number
3.5.4.9
uniprot
proteins
function
FUNCTION: Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. {ECO:0000250|UniProtKB:D3ZUA0}.
uniprot
proteins
mass_dalton
36438
uniprot
proteins
pathway_participation
PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion. {ECO:0000250|UniProtKB:D3ZUA0}.
uniprot
proteins
protein_family
Tetrahydrofolate dehydrogenase/cyclohydrolase family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
24733394
uniprot
proteins
sequence_length
338
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:D3ZUA0}; Peripheral membrane protein {ECO:0000250|UniProtKB:D3ZUA0}; Matrix side {ECO:0000250|UniProtKB:D3ZUA0}.
uniprot
proteins