DAZL
entrez
1618
canonical
uniprot
Q92904
canonical
ensembl
ENSG00000092345
resolver
ensp
ENSP00000250863
resolver
ensp
ENSP00000382373
resolver
genesymbol
DAZL
resolver
genesymbol_syn
DAZH
resolver
genesymbol_syn
DAZL1
resolver
genesymbol_syn
DAZLA
resolver
genesymbol_syn
SPGYLA
resolver
hgnc
HGNC:2685
resolver
uniprot
A0A140VK77
resolver
uniprot
O15396
resolver
uniprot
Q5HYB4
resolver
uniprot
Q92909
resolver
uniprot_entry
A0A140VK77_HUMAN
resolver
uniprot_entry
DAZL_HUMAN
resolver
uniprot_sec
O15396
resolver
uniprot_sec
Q5HYB4
resolver
uniprot_sec
Q92909
resolver
amino_acid_sequence
MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDKRVHHFRRSRAMLKSV
uniprot
proteins
function
FUNCTION: RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33178
uniprot
proteins
protein_family
RRM DAZ family
uniprot
proteins
pubmed
10857750
uniprot
proteins
pubmed
11390979
uniprot
proteins
pubmed
12414900
uniprot
proteins
pubmed
12511597
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
22021443
uniprot
proteins
pubmed
31429579
uniprot
proteins
pubmed
8896558
uniprot
proteins
pubmed
8968755
uniprot
proteins
pubmed
8968756
uniprot
proteins
pubmed
9294855
uniprot
proteins
sequence_length
295
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:31429579}. Nucleus {ECO:0000250}. Note=Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward. {ECO:0000250}.
uniprot
proteins