Klrg1
entrez
58975
canonical
uniprot
Q64335
canonical
ensembl
ENSRNOG00000014918
resolver
ensp
ENSRNOP00000020094
resolver
enst
ENSRNOT00000020094
resolver
genesymbol
Klrg1
resolver
genesymbol_syn
Mafa
resolver
uniprot_entry
KLRG1_RAT
resolver
amino_acid_sequence
MADNSIYSTLELPAAPRVQDDSRWKVKAVLHRPCVSYLVMVALGLLTVILMSLLLYQRTLCCGSKGFMCSQCSRCPNLWMRNGSHCYYFSMEKRDWNSSLKFCADKGSHLLTFPDNQGVNLFQEYVGEDFYWIGLRDIDGWRWEDGPALSLSILSNSVVQKCGTIHRCGLHASSCEVALQWICEKVLP
uniprot
proteins
function
FUNCTION: Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
21356
uniprot
proteins
post_translational_modification
PTM: Phosphorylated in response to monoclonal antibody G63 binding and antigenic stimulation. {ECO:0000269|PubMed:7568140}.
uniprot
proteins
pubmed
7568140
uniprot
proteins
pubmed
9120279
uniprot
proteins
sequence_length
188
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 35..55; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins