Li-Fraumeni syndrome
cv_term_accession
KW-0435
canonical
uniprot_keyword
KW-0435
canonical
name
Li-Fraumeni syndrome
uniprot
synonym
LFS
uniprot
synonym
SBLA syndrome
uniprot
synonym
Sarcoma family syndrome of Li and Fraumeni
uniprot
definition
Protein which, if defective, causes Li-Fraumeni syndrome (LFS), an autosomal dominant familial cancer predisposition syndrome associated with soft-tissue sarcoma, breast cancer, leukemia, osteosarcoma, melanoma, and cancer of the colon, pancreas, adrenal cortex and brain. Individuals with LFS are at increased risk for developing multiple primary cancers.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords