CCT2
entrez
10576
canonical
uniprot
P78371
canonical
ensembl
ENSG00000166226
resolver
ensp
ENSP00000299300
resolver
ensp
ENSP00000445471
resolver
genesymbol
CCT2
resolver
genesymbol
HEL-S-100n
resolver
genesymbol_syn
99D8.1
resolver
genesymbol_syn
CCT2
resolver
genesymbol_syn
CCTB
resolver
hgnc
HGNC:1615
resolver
uniprot
A8K402
resolver
uniprot
B5BTY7
resolver
uniprot
B7Z243
resolver
uniprot
B7Z7K4
resolver
uniprot
B7ZAT2
resolver
uniprot
Q14D36
resolver
uniprot
Q6IAT3
resolver
uniprot
V9HW96
resolver
uniprot_entry
TCPB_HUMAN
resolver
uniprot_entry
V9HW96_HUMAN
resolver
uniprot_sec
A8K402
resolver
uniprot_sec
B5BTY7
resolver
uniprot_sec
B7Z243
resolver
uniprot_sec
B7Z7K4
resolver
uniprot_sec
B7ZAT2
resolver
uniprot_sec
Q14D36
resolver
uniprot_sec
Q6IAT3
resolver
amino_acid_sequence
MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
function
FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis (PubMed:25467444, PubMed:36493755, PubMed:35449234, PubMed:37193829). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). {ECO:0000269|PubMed:20080638, ECO:0000269|PubMed:25467444, ECO:0000269|PubMed:35449234, ECO:0000269|PubMed:36493755, ECO:0000269|PubMed:37193829}.
uniprot
proteins
mass_dalton
57488
uniprot
proteins
protein_family
TCP-1 chaperonin family
uniprot
proteins
pubmed
12665801
uniprot
proteins
pubmed
14532270
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
19054851
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20080638
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25467444
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
27353360
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
33144677
uniprot
proteins
pubmed
35449234
uniprot
proteins
pubmed
36493755
uniprot
proteins
pubmed
37193829
uniprot
proteins
pubmed
9819444
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20080638}.
uniprot
proteins