GRAMD4
entrez
23151
canonical
uniprot
Q6IC98
canonical
ensembl
ENSG00000075240
resolver
ensp
ENSP00000354313
resolver
ensp
ENSP00000385689
resolver
ensp
ENSP00000639524
resolver
ensp
ENSP00000791977
resolver
genesymbol
GRAMD4
resolver
genesymbol_syn
DIP
resolver
genesymbol_syn
KIAA0767
resolver
hgnc
HGNC:29113
resolver
uniprot
A9IN51
resolver
uniprot
A9IN57
resolver
uniprot
Q68EN0
resolver
uniprot
Q9UGE6
resolver
uniprot
Q9Y4B9
resolver
uniprot_entry
GRAM4_HUMAN
resolver
uniprot_sec
A9IN51
resolver
uniprot_sec
A9IN57
resolver
uniprot_sec
Q68EN0
resolver
uniprot_sec
Q9UGE6
resolver
uniprot_sec
Q9Y4B9
resolver
amino_acid_sequence
MLRRLDKIRFRGHKRDDFLDLAESPNASDTECSDEIPLKVPRTSPRDSEELRDPAGPGTLIMATGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVLKARTEEQMAQQPPKGQAQASNGAERRSQGLSSRLQKWFYERFGEYVEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSVYTSAIAFTVYMNAVWHGWAIPLFLFLAILRLSLNYLIARGWRIQWSIVPEVSEPVEPPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEITQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERSSAAVSRRLQTTSSRSYVPSAPAGLGKEEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILSQYIKITSAAASGGDS
uniprot
proteins
function
FUNCTION: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (PubMed:15565177). Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (By similarity). {ECO:0000250|UniProtKB:Q8CB44, ECO:0000269|PubMed:15565177}.
uniprot
proteins
mass_dalton
66408
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
11937641
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15565177
uniprot
proteins
pubmed
16225677
uniprot
proteins
pubmed
18302964
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
9872452
uniprot
proteins
sequence_length
578
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8CB44}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with COX4I1. {ECO:0000269|PubMed:15565177}.
uniprot
proteins
transmembrane_region
TRANSMEM 240..260; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 334..354; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 356..376; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins