Krt1
entrez
300250
canonical
uniprot
Q6IMF3
canonical
ensembl
ENSRNOG00000028996
resolver
ensp
ENSRNOP00000029276
resolver
enst
ENSRNOT00000034450
resolver
genesymbol
Krt1
resolver
genesymbol_syn
Kb1
resolver
uniprot
A0A0G2JST3
resolver
uniprot
A1L113
resolver
uniprot
Q63115
resolver
uniprot_entry
A0A0G2JST3_RAT
resolver
uniprot_entry
K2C1_RAT
resolver
uniprot_sec
A1L113
resolver
uniprot_sec
Q63115
resolver
amino_acid_sequence
MSFQCSSRSLCRSGGGGGGRNFSSGSAGLVSFQRRSTSSSMRRSGGGGGGRFSGGGFCGSSGGGFGSKSLVNLGGGRSISISVAGGGSSYGGGFGGGSYGGGSFGGGSFGGGVGGGFGGGGFGGGGFGSGGGFGGGRFGGGFGPVCPPGGIQEVTINQSLLQPLNVEVDPQIQKVKSQEREQIKSLNDKFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTQNLDPFFESYISNLRRQVDSLKNDQSRMDSELKNMQDLVEEYRTKYEDEINKRTNAENEFVTIKKDVDSAYMNKAELQARVDNLQQDIDFFSTLYQMELSQMQTQISETNVVLSMDNNRTLDLDGIIAEVKAQYDSICQRSKAEAETFYQSKYEELQITAGKHGDSVKNTKMEISELNRVIQRLRSEIDSVKKQISQMQQNISDAEQRGEKALKDAQNKLNEIEDALTQAKEELTRLLRDYQELMNTKLALDMEIATYRKLLEGEEIRMSGECTPNVSVSVSTSHTSMSGTSSRGGGRYGSGGGGGGGTYGGGSRGGSYGGGSGGGSYGGCSSGGGSGGGSYGGGSSGGHRGGSGGGGGSSGGSYGGSSGGGRGGSSSGGGVKSSGSSSVKFVSTTYSRGTN
uniprot
proteins
function
FUNCTION: Structural component of intermediate filaments in suprabasal keratinocytes of stratified epithelia. Forms heteropolymers with a type I keratin, assembling into keratin intermediate filament networks that provide mechanical strength and structural stability to differentiating epidermal cells. May regulate the activity of kinases such as PKC and SRC by interacting with integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP, acts as a high-affinity receptor for kininogen-1 (HMWK). {ECO:0000250|UniProtKB:P04264}.
uniprot
proteins
mass_dalton
64831
uniprot
proteins
post_translational_modification
PTM: Undergoes deimination of some arginine residues (citrullination).
uniprot
proteins
protein_family
Intermediate filament family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15085952
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
625
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P04264}. Cytoplasm {ECO:0000250|UniProtKB:P04264}.
uniprot
proteins