Tmem107
entrez
691750
canonical
uniprot
D3ZFW5
canonical
ensembl
ENSRNOG00000006519
resolver
ensp
ENSRNOP00000089825
resolver
ensp
ENSRNOP00000099873
resolver
enst
ENSRNOT00000106758
resolver
enst
ENSRNOT00000170020
resolver
genesymbol
Tmem107
resolver
uniprot
A0A8I6ACI6
resolver
uniprot
A0ABK0L6D5
resolver
uniprot_entry
A0A8I6ACI6_RAT
resolver
uniprot_entry
A0ABK0L6D5_RAT
resolver
uniprot_entry
TM107_RAT
resolver
amino_acid_sequence
MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF
uniprot
proteins
function
FUNCTION: Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity). During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins (By similarity). {ECO:0000250|UniProtKB:Q6UX40, ECO:0000250|UniProtKB:Q9CPV0}.
uniprot
proteins
mass_dalton
15591
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
140
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250|UniProtKB:Q6UX40}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..27; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 83..103; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 113..133; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins