MPP1
entrez
4354
canonical
uniprot
Q00013
canonical
ensembl
ENSG00000130830
resolver
ensp
ENSP00000358547
resolver
ensp
ENSP00000377165
resolver
ensp
ENSP00000400155
resolver
ensp
ENSP00000577156
resolver
ensp
ENSP00000577159
resolver
ensp
ENSP00000625704
resolver
genesymbol
MPP1
resolver
genesymbol_syn
DXS552E
resolver
genesymbol_syn
EMP55
resolver
hgnc
HGNC:7219
resolver
uniprot
B4DZV5
resolver
uniprot
B4E325
resolver
uniprot
G3XAI1
resolver
uniprot
Q2TSB6
resolver
uniprot
Q5J7V5
resolver
uniprot_entry
B4E325_HUMAN
resolver
uniprot_entry
EM55_HUMAN
resolver
uniprot_sec
B4DZV5
resolver
uniprot_sec
G3XAI1
resolver
uniprot_sec
Q2TSB6
resolver
uniprot_sec
Q5J7V5
resolver
amino_acid_sequence
MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY
uniprot
proteins
function
FUNCTION: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
52296
uniprot
proteins
post_translational_modification
PTM: Palmitoylated. {ECO:0000269|PubMed:1713685}.
uniprot
proteins
protein_family
MAGUK family
uniprot
proteins
pubmed
1301163
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
16741958
uniprot
proteins
pubmed
1713685
uniprot
proteins
pubmed
17584769
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19144871
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22496366
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
29475958
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19144871}; Lipid-anchor {ECO:0000305|PubMed:1713685}. Cell projection, stereocilium {ECO:0000250|UniProtKB:P70290}. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with PALS1 in the retina, at the outer limiting membrane (OLM) (By similarity). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) (By similarity). Colocalizes with NF2 in non-myelin-forming Schwann cells (PubMed:19144871). {ECO:0000250|UniProtKB:P70290, ECO:0000269|PubMed:19144871}.
uniprot
proteins