Mpp2
entrez
50997
canonical
uniprot
Q9WV34
canonical
ensembl
ENSMUSG00000017314
resolver
ensp
ENSMUSP00000017458
resolver
ensp
ENSMUSP00000097967
resolver
ensp
ENSMUSP00000246937
resolver
ensp
ENSMUSP00000246939
resolver
ensp
ENSMUSP00000246947
resolver
genesymbol
Mpp2
resolver
genesymbol_syn
Dlgh2
resolver
uniprot
B1AQF8
resolver
uniprot
Q3T9W1
resolver
uniprot
Q3TT52
resolver
uniprot
Q3URK8
resolver
uniprot_entry
MPP2_MOUSE
resolver
uniprot_sec
B1AQF8
resolver
uniprot_sec
Q3T9W1
resolver
uniprot_sec
Q3TT52
resolver
uniprot_sec
Q3URK8
resolver
amino_acid_sequence
MPVAATNSESAMQQVLDNLGSLPNATGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEAVRDNNLELVQEILRDLAELAEQSSTAAELARILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRSASGSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLSPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGSAGLIPSQLLEEKRKAFVKRDLELTPTSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLILWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDYETLRAMNRAALESGVSTKQLTEADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY
uniprot
proteins
function
FUNCTION: Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (PubMed:26880549). Seems to negatively regulate SRC function in epithelial cells (By similarity). {ECO:0000250|UniProtKB:D3ZAA9, ECO:0000250|UniProtKB:Q14168, ECO:0000269|PubMed:26880549}.
uniprot
proteins
mass_dalton
61555
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SRC. {ECO:0000250|UniProtKB:Q14168}.
uniprot
proteins
protein_family
MAGUK family
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26880549
uniprot
proteins
sequence_length
552
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, dendrite {ECO:0000269|PubMed:26880549}. Postsynaptic density {ECO:0000269|PubMed:26880549}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q14168}. Membrane {ECO:0000250|UniProtKB:Q14168}. Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. {ECO:0000269|PubMed:26880549}.
uniprot
proteins