CDC42SE2
entrez
56990
canonical
uniprot
Q9NRR3
canonical
ensembl
ENSG00000158985
resolver
ensp
ENSP00000353706
resolver
ensp
ENSP00000378667
resolver
ensp
ENSP00000427421
resolver
ensp
ENSP00000562462
resolver
enst
ENST00000360515
resolver
enst
ENST00000395246
resolver
enst
ENST00000505065
resolver
enst
ENST00000892403
resolver
genesymbol
CDC42SE2
resolver
genesymbol_syn
SPEC2
resolver
hgnc
HGNC:18547
resolver
uniprot
B2R622
resolver
uniprot
Q4KMT9
resolver
uniprot_entry
C42S2_HUMAN
resolver
uniprot_sec
B2R622
resolver
uniprot_sec
Q4KMT9
resolver
amino_acid_sequence
MSEFWLCFNCCIAEQPQPKRRRRIDRSMIGEPTNFVHTAHVGSGDLFSGMNSVSSIQNQMQSKGGYGGGMPANVQMQLVDTKAG
uniprot
proteins
function
FUNCTION: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. {ECO:0000269|PubMed:10816584, ECO:0000269|PubMed:15840583}.
uniprot
proteins
mass_dalton
9223
uniprot
proteins
protein_family
CDC42SE/SPEC family
uniprot
proteins
pubmed
10816584
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15840583
uniprot
proteins
pubmed
17030554
uniprot
proteins
pubmed
17045588
uniprot
proteins
sequence_length
84
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Cell projection, phagocytic cup. Note=Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.
uniprot
proteins