Btbd7
entrez
238386
canonical
uniprot
Q8CFE5
canonical
ensembl
ENSMUSG00000041702
resolver
ensp
ENSMUSP00000046951
resolver
ensp
ENSMUSP00000152426
resolver
genesymbol
Btbd7
resolver
genesymbol_syn
Fup1
resolver
genesymbol_syn
Kiaa1525
resolver
uniprot
Q80TC3
resolver
uniprot
Q8BZY9
resolver
uniprot_entry
BTBD7_MOUSE
resolver
uniprot_sec
Q80TC3
resolver
uniprot_sec
Q8BZY9
resolver
amino_acid_sequence
MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEDKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDISTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNPLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAVLKWSSHPYGSKWVHRQAVHFLCEELSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTAEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSNAMPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPTAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSHHPSRSFSYPCNHSLFHCRTAPKPGPPPVYLPGVKVAPPDCTNTTGLGRQTVAAAAAAAAASAAIIPEKQVCPQPVLNDLMPDIAMGVSTLSLKDRRLPELAADTELCQTVSEAGTGPPQHLSCIPQRHTNTSRKKPTLEQKADGRENQQEYPDLYDFSNAACRPSTPAPGRHSPSPAHGRYFGPDLYSHNKASPNGLKSVYLPGQTSPKKQEDPRREYPPSPDGHPHRQKREPIRLDVVEQPPQRPDFPSAASENASHGPAHVRARTAVETDLTFGLTSNRPPSHSACSSEVLEERSSRRLTDSEPLGHGAHQRNADLERGDSISRGRRSPSKPDFLYKKSAL
uniprot
proteins
function
FUNCTION: Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. {ECO:0000269|PubMed:20671187}.
uniprot
proteins
mass_dalton
126243
uniprot
proteins
pubmed
11527404
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20671187
uniprot
proteins
sequence_length
1130
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11527404}.
uniprot
proteins