NAALAD2
entrez
10003
canonical
uniprot
Q9Y3Q0
canonical
ensembl
ENSG00000077616
resolver
ensembl
ENSG00000285516
resolver
ensp
ENSP00000320083
resolver
ensp
ENSP00000432481
resolver
ensp
ENSP00000495670
resolver
ensp
ENSP00000680186
resolver
enst
ENST00000321955
resolver
enst
ENST00000646420
resolver
genesymbol
NAALAD2
resolver
hgnc
HGNC:14526
resolver
uniprot
B3KQR4
resolver
uniprot
J3KNJ3
resolver
uniprot
Q4KKV4
resolver
uniprot
Q4VAM9
resolver
uniprot_entry
J3KNJ3_HUMAN
resolver
uniprot_entry
NALD2_HUMAN
resolver
uniprot_sec
B3KQR4
resolver
uniprot_sec
Q4KKV4
resolver
uniprot_sec
Q4VAM9
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by quisqualate.
uniprot
proteins
amino_acid_sequence
MAESRGRLYLWMCLAAALASFLMGFMVGWFIKPLKETTTSVRYHQSIRWKLVSEMKAENIKSFLRSFTKLPHLAGTEQNFLLAKKIQTQWKKFGLDSAKLVHYDVLLSYPNETNANYISIVDEHETEIFKTSYLEPPPDGYENVTNIVPPYNAFSAQGMPEGDLVYVNYARTEDFFKLEREMGINCTGKIVIARYGKIFRGNKVKNAMLAGAIGIILYSDPADYFAPEVQPYPKGWNLPGTAAQRGNVLNLNGAGDPLTPGYPAKEYTFRLDVEEGVGIPRIPVHPIGYNDAEILLRYLGGIAPPDKSWKGALNVSYSIGPGFTGSDSFRKVRMHVYNINKITRIYNVVGTIRGSVEPDRYVILGGHRDSWVFGAIDPTSGVAVLQEIARSFGKLMSKGWRPRRTIIFASWDAEEFGLLGSTEWAEENVKILQERSIAYINSDSSIEGNYTLRVDCTPLLYQLVYKLTKEIPSPDDGFESKSLYESWLEKDPSPENKNLPRINKLGSGSDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYETFELVEKFYDPTFKKQLSVAQLRGALVYELVDSKIIPFNIQDYAEALKNYAASIYNLSKKHDQQLTDHGVSFDSLFSAVKNFSEAASDFHKRLIQVDLNNPIAVRMMNDQLMLLERAFIDPLGLPGKLFYRHIIFAPSSHNKYAGESFPGIYDAIFDIENKANSRLAWKEVKKHISIAAFTIQAAAGTLKEVL
uniprot
proteins
ec_number
3.4.17.21
uniprot
proteins
function
FUNCTION: Has N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Also exhibits a dipeptidyl-peptidase IV type activity. Inactivates the peptide neurotransmitter N-acetylaspartylglutamate. {ECO:0000269|PubMed:10085079}.
uniprot
proteins
mass_dalton
83592
uniprot
proteins
protein_family
M28B subfamily
uniprot
proteins
protein_family
Peptidase M28 family
uniprot
proteins
pubmed
10085079
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
19678840
uniprot
proteins
sequence_length
740
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q04609}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q04609}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..31; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins