Kcnj9
entrez
16524
canonical
uniprot
P48543
canonical
ensembl
ENSMUSG00000038026
resolver
ensp
ENSMUSP00000060110
resolver
ensp
ENSMUSP00000141633
resolver
enst
ENSMUST00000062387
resolver
enst
ENSMUST00000194204
resolver
genesymbol
Kcnj9
resolver
genesymbol_syn
Girk3
resolver
uniprot
Q544N3
resolver
uniprot
Q9WUE1
resolver
uniprot_entry
KCNJ9_MOUSE
resolver
uniprot_entry
Q544N3_MOUSE
resolver
uniprot_sec
Q9WUE1
resolver
amino_acid_sequence
MAQENAAFSPGSEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGAGDGADKEHNGCLPPPESESKV
uniprot
proteins
function
FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor is controlled by G proteins. Unable to produce channel activity when expressed alone (PubMed:7926018). Forms a functional channel in association with KCNJ3/GIRK1 (PubMed:10341034). {ECO:0000269|PubMed:10341034, ECO:0000269|PubMed:7926018}.
uniprot
proteins
mass_dalton
43974
uniprot
proteins
protein_family
Inward rectifier-type potassium channel (TC 1.A.2.1) family
uniprot
proteins
protein_family
KCNJ9 subfamily
uniprot
proteins
pubmed
10341034
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7926018
uniprot
proteins
sequence_length
393
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 58..82; /note="Helical; Name=M1"; /evidence="ECO:0000250"; TRANSMEM 135..156; /note="Helical; Name=M2"; /evidence="ECO:0000250
uniprot
proteins