Hsd17b11
entrez
289456
canonical
uniprot
Q6AYS8
canonical
ensembl
ENSRNOG00000002210
resolver
ensembl
ENSRNOG00055026190
resolver
ensembl
ENSRNOG00060010768
resolver
ensp
ENSRNOP00000003004
resolver
ensp
ENSRNOP00055037062
resolver
ensp
ENSRNOP00060014189
resolver
enst
ENSRNOT00000003004
resolver
enst
ENSRNOT00055045193
resolver
enst
ENSRNOT00060018228
resolver
genesymbol
Hsd17b11
resolver
genesymbol_syn
Dhrs8
resolver
uniprot_entry
DHB11_RAT
resolver
amino_acid_sequence
MKYLLDLILLLPLLIVFCIESFIKRLIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQVHPFVVDCSQREEIYSAVRKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGCTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTNQKMIFVPGSIALLTVLERVFPERFLDVLKRRINVKFDAVVGYKDK
uniprot
proteins
ec_number
1.1.1.62
uniprot
proteins
function
FUNCTION: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. {ECO:0000250}.
uniprot
proteins
mass_dalton
32938
uniprot
proteins
protein_family
17-beta-HSD 3 subfamily
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9EQ06}. Lipid droplet {ECO:0000250|UniProtKB:Q9EQ06}. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation. {ECO:0000250|UniProtKB:Q9EQ06}.
uniprot
proteins