Milr1
entrez
380732
canonical
uniprot
Q3TB92
canonical
ensembl
ENSMUSG00000040528
resolver
ensp
ENSMUSP00000083538
resolver
ensp
ENSMUSP00000102406
resolver
ensp
ENSMUSP00000138513
resolver
ensp
ENSMUSP00000138617
resolver
ensp
ENSMUSP00000138678
resolver
ensp
ENSMUSP00000138742
resolver
ensp
ENSMUSP00000298966
resolver
ensp
ENSMUSP00000298969
resolver
ensp
ENSMUSP00000298970
resolver
enst
ENSMUST00000106794
resolver
enst
ENSMUST00000182896
resolver
genesymbol
Milr1
resolver
genesymbol_syn
Gm885
resolver
genesymbol_syn
Mca32
resolver
uniprot
A0A140T8Q6
resolver
uniprot
B2RTB7
resolver
uniprot
B7ZP18
resolver
uniprot
B7ZP19
resolver
uniprot
D6RUW9
resolver
uniprot
Q3TC23
resolver
uniprot
Q3TDY5
resolver
uniprot
Q3U5M7
resolver
uniprot
Q3U9F5
resolver
uniprot
S4R2F0
resolver
uniprot_entry
A0A140T8Q6_MOUSE
resolver
uniprot_entry
B7ZP19_MOUSE
resolver
uniprot_entry
MILR1_MOUSE
resolver
uniprot_entry
S4R2F0_MOUSE
resolver
uniprot_sec
B2RTB7
resolver
uniprot_sec
B7ZP18
resolver
uniprot_sec
D6RUW9
resolver
uniprot_sec
Q3TC23
resolver
uniprot_sec
Q3TDY5
resolver
uniprot_sec
Q3U5M7
resolver
uniprot_sec
Q3U9F5
resolver
amino_acid_sequence
MGDGDSPMCLSAVSFKGIRCWLDKLLLWALTISITLQNAAVDCTRVENNELPSPNLNSSMNVVRMGQNVSLSCSTKNTSVDITYSLFWGTKYLESKRRRGGAVDFHLRISNANESGPYKCKVNVSNLMKYSQDFNFTMAKDESCPSCRLSLLLPGLLLGILVIVLVLAYLIHLKYKKGKKTQREDQSKGSGDAPAQDELYVNACKTQTEQPQEIHYATPVFKEMAPMEEEGGTDGKADYIYSELTH
uniprot
proteins
function
FUNCTION: Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. {ECO:0000269|PubMed:20526344}.
uniprot
proteins
mass_dalton
27366
uniprot
proteins
mutagenesis
MUTAGEN 216; /note="Y->F: Abolishes interaction with PTPN6 and PTPN11. Loss of function; when associated with F-241."; /evidence="ECO:0000269|PubMed:20526344"; MUTAGEN 241; /note="Y->F: Abolishes interaction with PTPN6 and PTPN11. Loss of function; when associated with F-216."; /evidence="ECO:0000269|PubMed:20526344
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:20526344}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
20526344
uniprot
proteins
sequence_length
246
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20526344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20526344}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 151..171; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins