Tnfrsf22
entrez
79202
canonical
uniprot
Q9ER62
canonical
ensembl
ENSMUSG00000010751
resolver
ensp
ENSMUSP00000075018
resolver
ensp
ENSMUSP00000119297
resolver
genesymbol
Tnfrsf22
resolver
genesymbol_syn
Dctrailr2
resolver
genesymbol_syn
Tnfrh2
resolver
genesymbol_syn
Tnfrsf1al2
resolver
uniprot
Q8VHB9
resolver
uniprot
Q9CZA4
resolver
uniprot_entry
TNR22_MOUSE
resolver
uniprot_sec
Q8VHB9
resolver
uniprot_sec
Q9CZA4
resolver
amino_acid_sequence
MFGFFCSLVSSLSRWFLWRRLLLLLLLLLLNLPLQVKFAMLELHSFKCPAGEYWSKDVCCKNCSAGTFVKAPCEIPHTQGQCEKCHPGTFTEKDNYLDACILCSTCDKDQEMVADCSATSDRKCQCRTGLYYYDPKFPESCRPCTKCPQGIPVLQECNSTANTVCSSSVSNPRNRLFLLLSPLSVLIVSVVVFRIIRR
uniprot
proteins
function
FUNCTION: Receptor for the cytotoxic ligand TNFSF10/TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis possibly through ligand competition. Cannot induce the NF-kappa-B pathway. {ECO:0000269|PubMed:12466268}.
uniprot
proteins
mass_dalton
22375
uniprot
proteins
pubmed
11063728
uniprot
proteins
pubmed
12466268
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 21..41; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins