Evl
entrez
14026
canonical
uniprot
P70429
canonical
ensembl
ENSMUSG00000021262
resolver
ensp
ENSMUSP00000021689
resolver
ensp
ENSMUSP00000076916
resolver
ensp
ENSMUSP00000105480
resolver
ensp
ENSMUSP00000133072
resolver
ensp
ENSMUSP00000152364
resolver
ensp
ENSMUSP00000176603
resolver
ensp
ENSMUSP00000176604
resolver
enst
ENSMUST00000109854
resolver
enst
ENSMUST00000172409
resolver
genesymbol
Evl
resolver
uniprot
E9PVP4
resolver
uniprot
F8WJB9
resolver
uniprot
Q6PB99
resolver
uniprot
Q9ERU8
resolver
uniprot_entry
E9PVP4_MOUSE
resolver
uniprot_entry
EVL_MOUSE
resolver
uniprot_entry
F8WJB9_MOUSE
resolver
uniprot_entry
Q6PB99_MOUSE
resolver
uniprot_sec
Q9ERU8
resolver
amino_acid_sequence
MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASSTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSTQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATGPILPPGHPSSAASTTLSCSGPPPPPPPPVPPPPTGSTPPPPPPLPAGGAQGTNHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT
uniprot
proteins
function
FUNCTION: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. {ECO:0000269|PubMed:10087267, ECO:0000269|PubMed:10945997}.
uniprot
proteins
mass_dalton
44337
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PKA; phosphorylation abolishes binding to SH3 domains of ABL and SRC. {ECO:0000269|PubMed:10945997}.
uniprot
proteins
protein_family
Ena/VASP family
uniprot
proteins
pubmed
10069337
uniprot
proteins
pubmed
10087267
uniprot
proteins
pubmed
10404224
uniprot
proteins
pubmed
10945997
uniprot
proteins
pubmed
10993894
uniprot
proteins
pubmed
14506234
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8861907
uniprot
proteins
sequence_length
414
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10945997}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:10945997}. Cell projection, lamellipodium {ECO:0000269|PubMed:10945997}. Note=Targeted to the leading edge of lamellipodia and the distal tip of stress fibers through interaction with a number of proteins. In activated T-cells, localizes to the F-actin collar and the distal tip of microspikes. {ECO:0000269|PubMed:10945997}.
uniprot
proteins