Dhps
entrez
288923
canonical
uniprot
Q6AY53
canonical
ensembl
ENSRNOG00000004219
resolver
ensembl
ENSRNOG00055007592
resolver
ensembl
ENSRNOG00060015797
resolver
ensembl
ENSRNOG00065009913
resolver
ensp
ENSRNOP00000005656
resolver
ensp
ENSRNOP00055010106
resolver
ensp
ENSRNOP00060021692
resolver
ensp
ENSRNOP00065012027
resolver
enst
ENSRNOT00000005656
resolver
enst
ENSRNOT00055012689
resolver
enst
ENSRNOT00060027044
resolver
enst
ENSRNOT00065015921
resolver
genesymbol
Dhps
resolver
uniprot_entry
DHYS_RAT
resolver
amino_acid_sequence
MEGTPSGAAPSSALAAVLKHSSALPPESAQVQGYDFNRGVDYHALLEAYGTTGFQATNFGRAVQQVNAMIEKKLEPLAVDEDHHEDLTQSRRPLTGCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNDNYCKFEDWLMPILDQMVQEQNTEGVKWTPSKMISRLGKEINNPESVYYWAHKNHIPVLSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINMQAIFAKRTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRMDAQPVKVYADASLVFPLLVAETFAQKADAFRAEKNED
uniprot
proteins
ec_number
2.5.1.46
uniprot
proteins
function
FUNCTION: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. {ECO:0000250|UniProtKB:P49366}.
uniprot
proteins
mass_dalton
40705
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; eIF5A hypusination.
uniprot
proteins
protein_family
Deoxyhypusine synthase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
369
uniprot
proteins