PARD6B
entrez
84612
canonical
uniprot
Q9BYG5
canonical
ensembl
ENSG00000124171
resolver
ensp
ENSP00000360672
resolver
genesymbol
PARD6B
resolver
genesymbol_syn
PAR6B
resolver
hgnc
HGNC:16245
resolver
uniprot
A2A2A7
resolver
uniprot
Q9Y510
resolver
uniprot_entry
PAR6B_HUMAN
resolver
uniprot_sec
A2A2A7
resolver
uniprot_sec
Q9Y510
resolver
amino_acid_sequence
MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL
uniprot
proteins
function
FUNCTION: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
uniprot
proteins
mass_dalton
41182
uniprot
proteins
protein_family
PAR6 family
uniprot
proteins
pubmed
11260256
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12234671
uniprot
proteins
pubmed
12725730
uniprot
proteins
pubmed
15254234
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
372
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
uniprot
proteins