RAD52
entrez
5893
canonical
uniprot
P43351
canonical
ensembl
ENSG00000002016
resolver
ensp
ENSP00000351284
resolver
ensp
ENSP00000387901
resolver
ensp
ENSP00000440268
resolver
ensp
ENSP00000440486
resolver
ensp
ENSP00000574837
resolver
ensp
ENSP00000574839
resolver
ensp
ENSP00000574840
resolver
ensp
ENSP00000599040
resolver
ensp
ENSP00000599041
resolver
ensp
ENSP00000730101
resolver
enst
ENST00000536177
resolver
genesymbol
RAD52
resolver
hgnc
HGNC:9824
resolver
uniprot
B7Z2G8
resolver
uniprot
B7Z5Q6
resolver
uniprot
F5GX32
resolver
uniprot
Q13205
resolver
uniprot
Q5DR82
resolver
uniprot
Q9Y5T7
resolver
uniprot
Q9Y5T8
resolver
uniprot
Q9Y5T9
resolver
uniprot_entry
B7Z2G8_HUMAN
resolver
uniprot_entry
B7Z5Q6_HUMAN
resolver
uniprot_entry
F5GX32_HUMAN
resolver
uniprot_entry
Q5DR82_HUMAN
resolver
uniprot_entry
RAD52_HUMAN
resolver
uniprot_sec
Q13205
resolver
uniprot_sec
Q9Y5T7
resolver
uniprot_sec
Q9Y5T8
resolver
uniprot_sec
Q9Y5T9
resolver
amino_acid_sequence
MSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRPNMALGHPQLQQVTSPSRPSHAVIPADQDCSSRSLSSSAVESEATHQRKLRQKQLQQQFRERMEKQQVRVSTPSAEKSEAAPPAPPVTHSTPVTVSEPLLEKDFLAGVTQELIKTLEDNSEKWAVTPDAGDGVVKPSSRADPAQTSDTLALNNQMVTQNRTPHSVCHQKPQAKSGSWDLQTYSADQRTTGNWESHRKSQDMKKRKYDPS
uniprot
proteins
function
FUNCTION: Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. {ECO:0000269|PubMed:12379650, ECO:0000269|PubMed:8702565}.
uniprot
proteins
mass_dalton
46169
uniprot
proteins
mutagenesis
MUTAGEN 55; /note="R->A: Abolishes ssDNA-binding."; /evidence="ECO:0000269|PubMed:12191481"; MUTAGEN 65; /note="Y->A: Moderately defective in both ss and dsDNA-binding."; /evidence="ECO:0000269|PubMed:12191481"; MUTAGEN 152; /note="K->A: Abolishes ssDNA-binding."; /evidence="ECO:0000269|PubMed:12191481"; MUTAGEN 153; /note="R->A: Moderately defective in both ss and dsDNA-binding."; /evidence="ECO:0000269|PubMed:12191481"; MUTAGEN 156; /note="R->A: Moderately defective in both ss and dsDNA-binding."; /evidence="ECO:0000269|PubMed:12191481
uniprot
proteins
post_translational_modification
PTM: Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR. {ECO:0000269|PubMed:12379650}.
uniprot
proteins
protein_family
RAD52 family
uniprot
proteins
pubmed
10673031
uniprot
proteins
pubmed
12191481
uniprot
proteins
pubmed
12370410
uniprot
proteins
pubmed
12379650
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
31400850
uniprot
proteins
pubmed
31585101
uniprot
proteins
pubmed
7526206
uniprot
proteins
pubmed
7774919
uniprot
proteins
pubmed
7797537
uniprot
proteins
pubmed
8702565
uniprot
proteins
sequence_length
418
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins