Stx12
entrez
100226
canonical
uniprot
Q9ER00
canonical
ensembl
ENSMUSG00000028879
resolver
ensp
ENSMUSP00000030698
resolver
enst
ENSMUST00000030698
resolver
genesymbol
Stx12
resolver
uniprot
Q3UIV9
resolver
uniprot
Q921T9
resolver
uniprot_entry
STX12_MOUSE
resolver
uniprot_sec
Q3UIV9
resolver
uniprot_sec
Q921T9
resolver
amino_acid_sequence
MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQLQHSTNQLAKETNELLKELGSLPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQDLELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK
uniprot
proteins
function
FUNCTION: SNARE promoting fusion of transport vesicles with target membranes. Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. {ECO:0000250|UniProtKB:G3V7P1}.
uniprot
proteins
mass_dalton
31195
uniprot
proteins
protein_family
Syntaxin family
uniprot
proteins
pubmed
12070131
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
20098723
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28855648
uniprot
proteins
sequence_length
274
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane {ECO:0000250|UniProtKB:G3V7P1}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:G3V7P1}. Golgi apparatus membrane {ECO:0000250|UniProtKB:G3V7P1}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:G3V7P1}. Endomembrane system {ECO:0000250|UniProtKB:G3V7P1}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:G3V7P1}; Cytoplasmic side {ECO:0000250|UniProtKB:G3V7P1}. Early endosome membrane {ECO:0000250|UniProtKB:G3V7P1}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:G3V7P1}. Recycling endosome membrane {ECO:0000250|UniProtKB:G3V7P1}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:G3V7P1}.
uniprot
proteins
transmembrane_region
TRANSMEM 251..271; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins