Ctdp1
entrez
67655
canonical
uniprot
Q7TSG2
canonical
ensembl
ENSMUSG00000033323
resolver
ensp
ENSMUSP00000038938
resolver
ensp
ENSMUSP00000185724
resolver
genesymbol
Ctdp1
resolver
genesymbol_syn
Fcp1
resolver
uniprot
Q7TSS7
resolver
uniprot
Q9D4S8
resolver
uniprot_entry
CTDP1_MOUSE
resolver
uniprot_sec
Q7TSS7
resolver
uniprot_sec
Q9D4S8
resolver
amino_acid_sequence
MEAPPAAGVPTECTPAVAGAEVRCPGPTPLRLLEWKVAAGATVRIGSVLAVCETAASAQPAGPAPARAASGGCVRAARTERRLRSERAGVVRELCAQPGQVVAPGALLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGRQQVPLSTATVSMVHSVPELMVSSEQAEKLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCPQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFPGTGDVNAPPAARETQARRKVNHSSKGGDALEQALSVRDPEDGRPAPGVEHSNGLGKASRELNGGEAVPGVFPSKADEKEAWPLTRASPASSSSGHEPTEAPELPVSCEWDGRTTPGVQPTQGDAATQDLDFDLSSDSESSESSSRSEGQRAPAPQERTKAAPEHSGPQDTSGGRAAASPLGESGPSIHPHDKGSDLDTQEEGERDSLCGLGNGSVDRKEAETESQNSEQSGVTAGESLDQSVGEEEEEDTDDDDHLIHLEEILVRVHTDYYTKYDRYLNKELEEAPDIRKIVPELKSKVLADVAVIFSGLHPTNFPVEKTREHYHATALGAKVLTQLVLSPDAPDRATHLIAARAGTEKVRQAQECKHLHVVSPDWLWSCLERWDKVEEQLFPLIDDDTRTHRDNSPAVFPDRHSVLPTALFHPTPIHSKAHPGPEVRIYDSNTGKLIRMGPQGSAPAPSSAPLNHGEPSSFRAVQPHQQQMFGEELPESQDGEQPGPARRKRQPSMSEAMPLYTLCKEDLESMDKEVDDILGEGSDDSDIEKKKPEDQDNEQERAPKPRKPRAPGIRREQPVGLPSSGERSTPGMRGPRGHKRKLNEEDAASESSGESSNDDEEGSSSEADEMAAALEAELNDLM
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
104554
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. In the presence of TFIIF, the phosphorylated form has an increased CTD phosphatase activity. The phosphorylation is required for the physical interaction with GTF2F1 (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
960
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Midbody {ECO:0000250}. Note=Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively. {ECO:0000250}.
uniprot
proteins