CARD18
entrez
59082
canonical
uniprot
P57730
canonical
ensembl
ENSG00000255501
resolver
ensp
ENSP00000436691
resolver
enst
ENST00000530950
resolver
genesymbol
CARD18
resolver
genesymbol_syn
ICEBERG
resolver
hgnc
HGNC:28861
resolver
uniprot
A2RRF8
resolver
uniprot_entry
CAR18_HUMAN
resolver
uniprot_sec
A2RRF8
resolver
amino_acid_sequence
MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDLVTGKGPKSCCKFIKHLCEEDPQLASKMGLH
uniprot
proteins
function
FUNCTION: Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B. {ECO:0000269|PubMed:11051551}.
uniprot
proteins
mass_dalton
10138
uniprot
proteins
pubmed
11051551
uniprot
proteins
pubmed
11821383
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
90
uniprot
proteins