OIP5
entrez
11339
canonical
uniprot
O43482
canonical
ensembl
ENSG00000104147
resolver
ensp
ENSP00000220514
resolver
ensp
ENSP00000452851
resolver
enst
ENST00000220514
resolver
genesymbol
OIP5
resolver
genesymbol_syn
MIS18B
resolver
hgnc
HGNC:20300
resolver
uniprot
Q96BX7
resolver
uniprot_entry
MS18B_HUMAN
resolver
uniprot_sec
Q96BX7
resolver
amino_acid_sequence
MAAQPLRHRSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEPAAGPQLPSWLQPERCAVFQCAQCHAVLADSVHLAWDLSRSLGAVVFSRVTNNVVLEAPFLVGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPEN
uniprot
proteins
function
FUNCTION: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. {ECO:0000269|PubMed:17199038}.
uniprot
proteins
mass_dalton
24691
uniprot
proteins
mutagenesis
MUTAGEN 77; /note="V->E: Abolishes interaction with MIS18A; when associated with D-172."; /evidence="ECO:0000269|PubMed:26921242"; MUTAGEN 172; /note="Y->D: Abolishes interaction with MIS18A; when associated with E-77."; /evidence="ECO:0000269|PubMed:26921242
uniprot
proteins
protein_family
Mis18 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17199038
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26921242
uniprot
proteins
pubmed
9466265
uniprot
proteins
sequence_length
229
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17199038}. Chromosome {ECO:0000269|PubMed:17199038}. Chromosome, centromere {ECO:0000269|PubMed:17199038}. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
uniprot
proteins