Dnajb6
entrez
362293
canonical
uniprot
Q6AYU3
canonical
ensembl
ENSRNOG00000010353
resolver
ensp
ENSRNOP00000041883
resolver
ensp
ENSRNOP00000093872
resolver
enst
ENSRNOT00000035996
resolver
enst
ENSRNOT00000118469
resolver
genesymbol
Dnajb6
resolver
uniprot
A0A8I6AML5
resolver
uniprot_entry
A0A8I6AML5_RAT
resolver
uniprot_entry
DNJB6_RAT
resolver
amino_acid_sequence
MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGSRSRGAGSFFSAFSGFPSFGSGFPAFDTGFTPFGSLGHGGLTSFSSASFGGSGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECRRRGQPTPALAPGPAPAPARVPSQARPPTPAPTPAPAQTPAPSVSTRPQKPPRPAPTAKLVSKSNWEDEEQDRQRVPGNCDAPMTSAGLKEGGKRKKQKQKEDSKKKKSTKGNH
uniprot
proteins
function
FUNCTION: Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity. {ECO:0000250|UniProtKB:O75190}.
uniprot
proteins
mass_dalton
38922
uniprot
proteins
pubmed
11896048
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9915854
uniprot
proteins
sequence_length
357
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O75190}. Nucleus {ECO:0000250|UniProtKB:O75190}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:O75190}.
uniprot
proteins