Dcun1d3
entrez
233805
canonical
uniprot
Q8K0V2
canonical
ensembl
ENSMUSG00000048787
resolver
ensp
ENSMUSP00000058968
resolver
ensp
ENSMUSP00000095686
resolver
ensp
ENSMUSP00000102129
resolver
ensp
ENSMUSP00000147253
resolver
ensp
ENSMUSP00000222276
resolver
ensp
ENSMUSP00000222277
resolver
ensp
ENSMUSP00000222279
resolver
ensp
ENSMUSP00000338742
resolver
ensp
ENSMUSP00000338745
resolver
enst
ENSMUST00000059851
resolver
enst
ENSMUST00000098080
resolver
enst
ENSMUST00000106519
resolver
enst
ENSMUST00000207233
resolver
genesymbol
Dcun1d3
resolver
genesymbol_syn
SCCRO3
resolver
uniprot_entry
DCNL3_MOUSE
resolver
amino_acid_sequence
MGQCVTKCKNPSSTLGSKNGDRDPSNKSHSRRGASHREEQVPPCGKPAGDILVNGTKKAEAATEACQLPTSSGDAGRESKTNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREVEGRGTLSSGQEGLCPEEQT
uniprot
proteins
function
FUNCTION: Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the SCF ubiquitin E3 ligase complex, after UV damage. At the cell membrane, can promote and as well inhibit cullins neddylation. {ECO:0000250|UniProtKB:Q8IWE4}.
uniprot
proteins
mass_dalton
34439
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
26792857
uniprot
proteins
sequence_length
304
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8IWE4}. Cytoplasm {ECO:0000250|UniProtKB:Q8IWE4}. Nucleus {ECO:0000250|UniProtKB:Q8IWE4}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8IWE4}. Note=After UVC treatment, the protein enters to the nucleus gradually. Cell membrane localization is essential for CUL3 neddylation. {ECO:0000250|UniProtKB:Q8IWE4}.
uniprot
proteins