Trmt5
entrez
76357
canonical
uniprot
Q9D0C4
canonical
ensembl
ENSMUSG00000034442
resolver
ensp
ENSMUSP00000112121
resolver
ensp
ENSMUSP00000348731
resolver
genesymbol
Trmt5
resolver
genesymbol_syn
Kiaa1393
resolver
genesymbol_syn
Trm5
resolver
uniprot
Q5DTY1
resolver
uniprot_entry
TRM5_MOUSE
resolver
uniprot_sec
Q5DTY1
resolver
amino_acid_sequence
MRIVWKLFGFSRRLLQVEWCHPSESILLFTLVPRLRKAPSVFLLGQRQGLSTMPEIEASVRDSELFSPPSDVRGMRELDRTAFKKTVSIPVLKARKEVVNRLMRALRRVALQRPGIKRVIEDPKDEDSRLIMLDPYRMLTADSFDKAELGVLKELDVSPQLSQYNLELTYENFKSEEILKAVLPEGQDVTSGFSRVGHIAHLNLRDHQLPFKHLIGQVMVDKNPGITSAVNKTSNIDNTYRNFQMEVLCGEENMLTKVRENNYTYEFDFSKVYWNPRLSTEHGRITELLNPGDVLFDVFAGVGPFAIPAARKNCTVFANDLNPESHKWLLHNCKLNKVDQKVKVFNMDGKDFIQGPVREELMLRLGLSAEAKPSVHIVMNLPAKAIEFLSVFRSLLDGQPCSTELLPTVHCYCFSKDSDPAKDVRQQAEAVLGVSLETSSSVHLVRNVAPNKEMLCITFQIPTATLYRNQSLSLQNDQEPPLKRQKTGDPFSGEPQIASDS
uniprot
proteins
ec_number
2.1.1.228
uniprot
proteins
function
FUNCTION: Involved in mitochondrial tRNA methylation (By similarity). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. {ECO:0000250|UniProtKB:Q32P41, ECO:0000255|HAMAP-Rule:MF_03152}.
uniprot
proteins
mass_dalton
56794
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
TRM5/TYW2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
501
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000255|HAMAP-Rule:MF_03152}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03152}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03152}. Note=Predominantly in the mitochondria and in the nucleus. {ECO:0000255|HAMAP-Rule:MF_03152}.
uniprot
proteins