Sult1d1
entrez
53315
canonical
uniprot
Q3UZZ6
canonical
ensembl
ENSMUSG00000029273
resolver
ensp
ENSMUSP00000108940
resolver
enst
ENSMUST00000113314
resolver
genesymbol
Sult1d1
resolver
genesymbol_syn
St1d1
resolver
uniprot
O35401
resolver
uniprot
Q6NZD1
resolver
uniprot
Q9R2C2
resolver
uniprot_entry
ST1D1_MOUSE
resolver
uniprot_sec
O35401
resolver
uniprot_sec
Q6NZD1
resolver
uniprot_sec
Q9R2C2
resolver
amino_acid_sequence
MDNKLDVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWVSEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYEDMKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRSEI
uniprot
proteins
ec_number
2.8.2.-
uniprot
proteins
function
FUNCTION: Sulfotransferase with broad substrate specificity that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, such as dopamine, prostaglandins, leukotriene E4, drugs and xenobiotic compounds. Has sulfotransferase activity towards p-nitrophenol, 2-naphthylamine and minoxidil (in vitro). Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. {ECO:0000269|PubMed:15087475, ECO:0000269|PubMed:18977225, ECO:0000269|PubMed:19966186, ECO:0000269|PubMed:9647753, ECO:0000269|PubMed:9920733}.
uniprot
proteins
mass_dalton
35083
uniprot
proteins
mutagenesis
MUTAGEN 247; /note="E->A: No effect on enzyme activity against dopamine."; /evidence="ECO:0000269|PubMed:18977225"; MUTAGEN 247; /note="E->L: Reduces enzyme activity against dopamine."; /evidence="ECO:0000269|PubMed:18977225
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
15087475
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18977225
uniprot
proteins
pubmed
19073143
uniprot
proteins
pubmed
19344693
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19966186
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9647753
uniprot
proteins
pubmed
9920733
uniprot
proteins
sequence_length
295
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19966186}.
uniprot
proteins