TMEM205
entrez
374882
canonical
uniprot
Q6UW68
canonical
ensembl
ENSG00000105518
resolver
ensp
ENSP00000346954
resolver
ensp
ENSP00000398258
resolver
ensp
ENSP00000465149
resolver
ensp
ENSP00000465483
resolver
ensp
ENSP00000465553
resolver
ensp
ENSP00000466495
resolver
ensp
ENSP00000466986
resolver
ensp
ENSP00000468733
resolver
ensp
ENSP00000523573
resolver
enst
ENST00000354882
resolver
enst
ENST00000447337
resolver
enst
ENST00000586590
resolver
enst
ENST00000586956
resolver
enst
ENST00000587948
resolver
enst
ENST00000588560
resolver
enst
ENST00000589555
resolver
enst
ENST00000593256
resolver
enst
ENST00000853514
resolver
genesymbol
TMEM205
resolver
hgnc
HGNC:29631
resolver
uniprot_entry
TM205_HUMAN
resolver
amino_acid_sequence
MEEGGNLGGLIKMVHLLVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHAWAQLTFWEASQLYLLFLSLTLATVNARWLEPRTTAAMWALQTVEKERGLGGEVPGSHQGPDPYRQLREKDPKYSALRQNFFRYHGLSSLCNLGCVLSNGLCLAGLALEIRSL
uniprot
proteins
function
FUNCTION: In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin. {ECO:0000269|PubMed:20589834}.
uniprot
proteins
mass_dalton
21198
uniprot
proteins
protein_family
TMEM205 family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20589834
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
189
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:20589834}; Multi-pass membrane protein {ECO:0000269|PubMed:20589834}. Note=Located on cell surface microvilli. In cancer cells, transition in subcellular location from cell surface to intracellular regions correlates the progression of cisplatin resistance.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 81..101; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 166..186; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins