Slc35f2
entrez
72022
canonical
uniprot
Q7TML3
canonical
ensembl
ENSMUSG00000042195
resolver
ensp
ENSMUSP00000046528
resolver
ensp
ENSMUSP00000359228
resolver
enst
ENSMUST00000048670
resolver
genesymbol
Slc35f2
resolver
uniprot
Q9DB62
resolver
uniprot_entry
S35F2_MOUSE
resolver
uniprot_sec
Q9DB62
resolver
amino_acid_sequence
MEAESPASAGASEPRALGTVDSIGSQLSRIRRKLFTWDILKTIALGQMLSLCICGTAITSQYLAEKYRVNTPMLQSFINYCLLFLVYTLMLAFQSGSDNLLEILRRKWWKYTLLGLADVEANYLIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILRARYKVIHFIAVFVCLLGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAVSNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIARIQWDWKIALLFVAFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFFGLFLFEYKFSGLYILSFTVIMVGFILYCSTPTRTVEPPESSVPPVTSIGIDNLGLKLEESGLPETHSAVL
uniprot
proteins
function
FUNCTION: High affinity plasma membrane importer of the nucleobase queuine (q) and its nucleoside queuosine (Q), two bacterially derived micronutrients acquired from the gut microbiome and diet. Following cellular uptake, queuosine is incorporated at the wobble base (position 34) of tRNAs that decode histidine, tyrosine, aspartate, and asparagine codons, which is important for efficient translation. Also involved in choline transport, although the underlying transport mechanism remains to be elucidated (By similarity). {ECO:0000250|UniProtKB:Q8IXU6}.
uniprot
proteins
mass_dalton
41635
uniprot
proteins
protein_family
SLC35F solute transporter family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8IXU6}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8IXU6}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 108..125; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 195..215; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 227..247; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 263..283; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 290..310; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins