Adprm
entrez
287406
canonical
uniprot
Q5M886
canonical
ensembl
ENSRNOG00000003397
resolver
ensp
ENSRNOP00000004560
resolver
enst
ENSRNOT00000004560
resolver
genesymbol
Adprm
resolver
uniprot
A0A8L2Q2A8
resolver
uniprot
A9Y0H8
resolver
uniprot_entry
A0A8L2Q2A8_RAT
resolver
uniprot_entry
ADPRM_RAT
resolver
uniprot_sec
A9Y0H8
resolver
activity_regulation
ACTIVITY REGULATION: Not activated by Mg(2+). {ECO:0000269|PubMed:22848751}.
uniprot
proteins
amino_acid_sequence
MADKPDPSSPADGPEPLFSFGVIADIQYADLEDGYNFQRSRRRYYRHSLVHLQGAIEDWNKESSMPCCVLQLGDIIDGYNAQYKVSEKSLELVMNTFQMLKVPVHHTWGNHEFYNFSRDYLANSKLNSKFLEDQIPQHPETTPSENYYAYHFVPFPKFRFILLDSYDLSVLGIDQFSPKYEQCMKILREHNPNVELNSPQGLSEPQYVQFNGGFSQEQLNWLNEVLTFSDANQEKVVIVSHLPIYPEASDSVCLAWNYVDALSIIWSHQCVVCFLAGHTHDGGYSEDPFGVHHVNLEGVIETAPDSQAFGTVHVYPDKMLLKGRGRVPDRIMNYKRE
uniprot
proteins
ec_number
3.6.1.16
uniprot
proteins
ec_number
3.6.1.53
uniprot
proteins
function
FUNCTION: Hydrolyzes ADP-ribose, ADP, CDP-glycerol, CDP-choline, CDP-ethanolamine and cyclic ADP-ribose (cADPR), but not other non-reducing ADP-sugars or CDP-glucose (PubMed:18352857, PubMed:19379742). May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress. {ECO:0000269|PubMed:18352857, ECO:0000269|PubMed:19379742}.
uniprot
proteins
mass_dalton
38712
uniprot
proteins
protein_family
ADPRibase-Mn family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18352857
uniprot
proteins
pubmed
19379742
uniprot
proteins
pubmed
22848751
uniprot
proteins
sequence_length
337
uniprot
proteins