MED10
entrez
84246
canonical
uniprot
Q9BTT4
canonical
ensembl
ENSG00000133398
resolver
ensembl
ENSG00000291745
resolver
ensp
ENSP00000255764
resolver
ensp
ENSP00000517281
resolver
enst
ENST00000255764
resolver
enst
ENST00000708561
resolver
genesymbol
MED10
resolver
hgnc
HGNC:28760
resolver
uniprot
C6G491
resolver
uniprot_entry
MED10_HUMAN
resolver
uniprot_sec
C6G491
resolver
amino_acid_sequence
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFIVTGLQDIDKCRQQLHDITVPLEVFEYIDQGRNPQLYTKECLERALAKNEQVKGKIDTMKKFKSLLIQELSKVFPEDMAKYRSIRGEDHPPS
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
uniprot
proteins
mass_dalton
15688
uniprot
proteins
protein_family
Mediator complex subunit 10 family
uniprot
proteins
pubmed
10024883
uniprot
proteins
pubmed
10993082
uniprot
proteins
pubmed
15175163
uniprot
proteins
pubmed
15334068
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15989967
uniprot
proteins
pubmed
21269460
uniprot
proteins
sequence_length
135
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins