Gid4
entrez
66771
canonical
uniprot
Q9CPY6
canonical
ensembl
ENSMUSG00000018415
resolver
ensp
ENSMUSP00000064926
resolver
ensp
ENSMUSP00000135441
resolver
enst
ENSMUST00000070681
resolver
enst
ENSMUST00000139477
resolver
genesymbol
Gid4
resolver
uniprot
Q3TP79
resolver
uniprot
Q7TT31
resolver
uniprot
Q99JE9
resolver
uniprot_entry
GID4_MOUSE
resolver
uniprot_sec
Q3TP79
resolver
uniprot_sec
Q7TT31
resolver
uniprot_sec
Q99JE9
resolver
amino_acid_sequence
MPVRTECPPPAGASTTSAASLIPPPPINTQQPGVATSLLYSGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHVPEHSAPIYEFR
uniprot
proteins
function
FUNCTION: Substrate-recognition subunit of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Binds proteins and peptides with a Pro/N-degron consisting of an unmodified N-terminal Pro followed by a small residue, and has the highest affinity for the peptide Pro-Gly-Leu-Trp. Binds peptides with an N-terminal sequence of the type Pro-[Ala,Gly]-[Leu,Met,Gln,Ser,Tyr]-[Glu,Gly,His,Ser,Val,Trp,Tyr]. Does not bind peptides with an acetylated N-terminal Pro residue. {ECO:0000250|UniProtKB:Q8IVV7}.
uniprot
proteins
mass_dalton
24863
uniprot
proteins
protein_family
GID4/VID24 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
217
uniprot
proteins