Pax7
entrez
18509
canonical
uniprot
P47239
canonical
ensembl
ENSMUSG00000028736
resolver
ensp
ENSMUSP00000030508
resolver
ensp
ENSMUSP00000133536
resolver
ensp
ENSMUSP00000207574
resolver
enst
ENSMUST00000030508
resolver
enst
ENSMUST00000174681
resolver
genesymbol
Pax7
resolver
genesymbol_syn
Pax-7
resolver
uniprot
G3UX36
resolver
uniprot
Q9ES16
resolver
uniprot_entry
G3UX36_MOUSE
resolver
uniprot_entry
PAX7_MOUSE
resolver
uniprot_sec
Q9ES16
resolver
amino_acid_sequence
MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRIKFGKKEDDEEGDKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSNPSAVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGYSVDPVAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY
uniprot
proteins
function
FUNCTION: Transcription factor that is involved in the regulation of muscle stem cells proliferation, playing a role in myogenesis and muscle regeneration. {ECO:0000269|PubMed:22862948, ECO:0000269|PubMed:34059674}.
uniprot
proteins
mass_dalton
54939
uniprot
proteins
mutagenesis
MUTAGEN 105; /note="K->R: Abolished acetylation by KAT8, leading to reduced transcription factor activity; when associated with R-139."; /evidence="ECO:0000269|PubMed:34059674"; MUTAGEN 139; /note="K->R: Abolished acetylation by KAT8, leading to reduced transcription factor activity; when associated with R-105."; /evidence="ECO:0000269|PubMed:34059674
uniprot
proteins
post_translational_modification
PTM: Acetylation at Lys-105 and Lys-139 by KAT8 is required for high-level transcription factor activity (PubMed:34059674). Deacetylated by SIRT2 (PubMed:34059674). {ECO:0000269|PubMed:34059674}.
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
11030621
uniprot
proteins
pubmed
1982921
uniprot
proteins
pubmed
22862948
uniprot
proteins
pubmed
34059674
uniprot
proteins
sequence_length
503
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:22862948, ECO:0000269|PubMed:34059674}.
uniprot
proteins