BTG4
entrez
54766
canonical
uniprot
Q9NY30
canonical
ensembl
ENSG00000137707
resolver
ensp
ENSP00000348300
resolver
ensp
ENSP00000432018
resolver
ensp
ENSP00000508793
resolver
ensp
ENSP00000509850
resolver
enst
ENST00000689553
resolver
enst
ENST00000692032
resolver
genesymbol
BTG4
resolver
genesymbol_syn
PC3B
resolver
hgnc
HGNC:13862
resolver
uniprot
A0A8I5KVE8
resolver
uniprot
Q8NEH7
resolver
uniprot_entry
A0A8I5KVE8_HUMAN
resolver
uniprot_entry
BTG4_HUMAN
resolver
uniprot_sec
Q8NEH7
resolver
amino_acid_sequence
MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCIRINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGRWEEWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPKVSNPKSIYQVENLKQPFQSWLQIPRKKNVVDGRVGLLGNTYHGSQKHPKCYRPAMHRLDRIL
uniprot
proteins
disease_involvement
DISEASE: Oocyte/zygote/embryo maturation arrest 8 (OZEMA8) [MIM:619009]: An autosomal recessive infertility disorder due to failure of the fertilized ovum to undergo zygotic cleavage. {ECO:0000269|PubMed:32502391}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E (By similarity). Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development (PubMed:32502391). {ECO:0000250|UniProtKB:O70552, ECO:0000269|PubMed:32502391}.
uniprot
proteins
mass_dalton
25970
uniprot
proteins
protein_family
BTG family
uniprot
proteins
pubmed
10995567
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
32502391
uniprot
proteins
sequence_length
223
uniprot
proteins