LIPG
entrez
9388
canonical
uniprot
Q9Y5X9
canonical
ensembl
ENSG00000101670
resolver
ensp
ENSP00000261292
resolver
ensp
ENSP00000387978
resolver
enst
ENST00000427224
resolver
genesymbol
LIPG
resolver
hgnc
HGNC:6623
resolver
uniprot
B0LPG6
resolver
uniprot
B4DTR8
resolver
uniprot
F8WAE0
resolver
uniprot
Q6P9C8
resolver
uniprot
Q6UW82
resolver
uniprot_entry
B4DTR8_HUMAN
resolver
uniprot_entry
F8WAE0_HUMAN
resolver
uniprot_entry
LIPG_HUMAN
resolver
uniprot_sec
B0LPG6
resolver
uniprot_sec
Q6P9C8
resolver
uniprot_sec
Q6UW82
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by serum and NaCl. {ECO:0000269|PubMed:12032167}.
uniprot
proteins
amino_acid_sequence
MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWFRKCRDGWRMKNETSPTVELP
uniprot
proteins
ec_number
3.1.1.3
uniprot
proteins
ec_number
3.1.1.32
uniprot
proteins
function
FUNCTION: Exerts both phospholipase and triglyceride lipase activities (PubMed:10192396, PubMed:10318835, PubMed:12032167). More active as a phospholipase than a triglyceride lipase (PubMed:12032167). Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates (PubMed:12032167). Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins (PubMed:10192396, PubMed:12032167). {ECO:0000269|PubMed:10192396, ECO:0000269|PubMed:10318835, ECO:0000269|PubMed:12032167}.
uniprot
proteins
mass_dalton
56795
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
Lipase family
uniprot
proteins
pubmed
10192396
uniprot
proteins
pubmed
10318835
uniprot
proteins
pubmed
12032167
uniprot
proteins
pubmed
12966036
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
19567873
uniprot
proteins
sequence_length
500
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10318835}.
uniprot
proteins