Slc38a7
entrez
234595
canonical
uniprot
Q8BWH0
canonical
ensembl
ENSMUSG00000036534
resolver
ensp
ENSMUSP00000037023
resolver
ensp
ENSMUSP00000148659
resolver
ensp
ENSMUSP00000201012
resolver
enst
ENSMUST00000040481
resolver
enst
ENSMUST00000212270
resolver
genesymbol
Slc38a7
resolver
genesymbol_syn
Snat7
resolver
uniprot
Q3TBN9
resolver
uniprot
Q8K2B1
resolver
uniprot_entry
S38A7_MOUSE
resolver
uniprot_sec
Q3TBN9
resolver
uniprot_sec
Q8K2B1
resolver
amino_acid_sequence
MAQVSINSDYSEWASSTDAGERARLLQSPCVDVVPKSEGEASPGDPDSGTTSTLGAVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMSKEPDGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASFLSVVGTWYVTAIIIIKYIWPDKEMRPGDILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYKGMPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFIFPGLCLIQAKLSEMEEVKPASWWALVSYGVLLVTLGAFIFGQTTANAIFVDLLA
uniprot
proteins
function
FUNCTION: Symporter that selectively cotransports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participates in mTORC1 activation (PubMed:21511949, PubMed:28416685). The transport activity requires an acidic lysosomal lumen (By similarity). {ECO:0000250|UniProtKB:Q9NVC3, ECO:0000269|PubMed:21511949, ECO:0000269|PubMed:28416685}.
uniprot
proteins
mass_dalton
49913
uniprot
proteins
protein_family
Amino acid/polyamine transporter 2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21511949
uniprot
proteins
pubmed
28416685
uniprot
proteins
sequence_length
463
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q9NVC3}; Multi-pass membrane protein {ECO:0000255}. Cell projection, axon {ECO:0000269|PubMed:21511949}. Note=In neurons, located in soma. {ECO:0000269|PubMed:21511949}.
uniprot
proteins
transmembrane_region
TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 130..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 206..226; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 240..260; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 283..303; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 320..340; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 372..392; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 396..416; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 429..449; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins