Efr3b
entrez
668212
canonical
uniprot
Q6ZQ18
canonical
ensembl
ENSMUSG00000020658
resolver
ensp
ENSMUSP00000106809
resolver
ensp
ENSMUSP00000151788
resolver
genesymbol
Efr3b
resolver
genesymbol_syn
Kiaa0953
resolver
uniprot
B2RXT1
resolver
uniprot_entry
EFR3B_MOUSE
resolver
uniprot_sec
B2RXT1
resolver
amino_acid_sequence
MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQAPEKEKENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAIIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGSKIIKEHEECMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSVHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPTYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLSQNLDGVVIEFLFRQSKISEVLGGSGYNSDRLCLPYIPQLTDEDRLSKRKSIGETISLQVEVESRNSPEKEERVPAEEITYETLKKAIVDSVAVEEQERERQRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISAAYGQPQNHSIPVYEMKFPDLCVY
uniprot
proteins
function
FUNCTION: Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, EFR3B probably acts as the membrane-anchoring component. Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect. {ECO:0000250|UniProtKB:Q9Y2G0}.
uniprot
proteins
mass_dalton
92406
uniprot
proteins
post_translational_modification
PTM: Palmitoylated at its N-terminus, anchoring the protein to the plasma membrane. {ECO:0000250|UniProtKB:Q9Y2G0}.
uniprot
proteins
protein_family
EFR3 family
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25380825
uniprot
proteins
sequence_length
817
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9Y2G0}; Lipid-anchor {ECO:0000250|UniProtKB:Q9Y2G0}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9Y2G0}. Note=Palmitoylation anchors the protein to the plasma membrane. A small amount is observed in the cytosol. {ECO:0000250|UniProtKB:Q9Y2G0}.
uniprot
proteins