SLK
entrez
9748
canonical
uniprot
Q9H2G2
canonical
ensembl
ENSG00000065613
resolver
ensp
ENSP00000336824
resolver
ensp
ENSP00000358770
resolver
ensp
ENSP00000616432
resolver
ensp
ENSP00000616435
resolver
genesymbol
SLK
resolver
genesymbol_syn
KIAA0204
resolver
genesymbol_syn
STK2
resolver
hgnc
HGNC:11088
resolver
uniprot
D3DRA0
resolver
uniprot
D3DRA1
resolver
uniprot
O00211
resolver
uniprot
Q6P1Z4
resolver
uniprot
Q86WU7
resolver
uniprot
Q86WW1
resolver
uniprot
Q92603
resolver
uniprot
Q9NQL0
resolver
uniprot
Q9NQL1
resolver
uniprot_entry
SLK_HUMAN
resolver
uniprot_sec
D3DRA0
resolver
uniprot_sec
D3DRA1
resolver
uniprot_sec
O00211
resolver
uniprot_sec
Q6P1Z4
resolver
uniprot_sec
Q86WU7
resolver
uniprot_sec
Q86WW1
resolver
uniprot_sec
Q92603
resolver
uniprot_sec
Q9NQL0
resolver
uniprot_sec
Q9NQL1
resolver
amino_acid_sequence
MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Mediates apoptosis and actin stress fiber dissolution. {ECO:0000250}.
uniprot
proteins
mass_dalton
142695
uniprot
proteins
mutagenesis
MUTAGEN 63; /note="K->R: Loss of activity."; /evidence="ECO:0000269|PubMed:10699464
uniprot
proteins
post_translational_modification
PTM: Proteolytically cleaved by caspase-3.; PTM: Autophosphorylated. {ECO:0000269|PubMed:10699464}.
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
STE Ser/Thr protein kinase family
uniprot
proteins
protein_family
STE20 subfamily
uniprot
proteins
pubmed
10699464
uniprot
proteins
pubmed
11149944
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28940097
uniprot
proteins
pubmed
29288388
uniprot
proteins
pubmed
9039502
uniprot
proteins
sequence_length
1235
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins