Fip1l1
entrez
66899
canonical
uniprot
Q9D824
canonical
ensembl
ENSMUSG00000029227
resolver
ensp
ENSMUSP00000079059
resolver
ensp
ENSMUSP00000109163
resolver
ensp
ENSMUSP00000109164
resolver
ensp
ENSMUSP00000250565
resolver
ensp
ENSMUSP00000250566
resolver
ensp
ENSMUSP00000250567
resolver
ensp
ENSMUSP00000250568
resolver
ensp
ENSMUSP00000250569
resolver
genesymbol
Fip1l1
resolver
uniprot
Q8BWX7
resolver
uniprot
Q99LH0
resolver
uniprot
Q9DBB2
resolver
uniprot_entry
FIP1_MOUSE
resolver
uniprot_sec
Q8BWX7
resolver
uniprot_sec
Q99LH0
resolver
uniprot_sec
Q9DBB2
resolver
amino_acid_sequence
MSAGEVERLVELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEEEAAENGVAKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKAGGRVYGNTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKEAALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKASSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSDRSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLTSSAPSWPSLVDTTKQWDYYARREKDRDRDRERDRDRERERDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPVPEQESTEAAPAE
uniprot
proteins
function
FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
64959
uniprot
proteins
protein_family
FIP1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19224921
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
581
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins