Timm8a1
entrez
30058
canonical
uniprot
Q9WVA2
canonical
ensembl
ENSMUSG00000048007
resolver
ensp
ENSMUSP00000050156
resolver
enst
ENSMUST00000054213
resolver
genesymbol
Timm8a1
resolver
genesymbol_syn
Ddp1
resolver
genesymbol_syn
Tim8a
resolver
genesymbol_syn
Timm8a
resolver
uniprot
Q542E5
resolver
uniprot_entry
TIM8A_MOUSE
resolver
uniprot_sec
Q542E5
resolver
amino_acid_sequence
MESSTSSSGSALGAVDPQLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD
uniprot
proteins
function
FUNCTION: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11042
uniprot
proteins
protein_family
Small Tim family
uniprot
proteins
pubmed
10611480
uniprot
proteins
pubmed
10873677
uniprot
proteins
pubmed
15254020
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
97
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
uniprot
proteins