ICAM5
entrez
7087
canonical
uniprot
Q9UMF0
canonical
ensembl
ENSG00000105376
resolver
ensp
ENSP00000221980
resolver
enst
ENST00000221980
resolver
genesymbol
ICAM5
resolver
genesymbol_syn
TLCN
resolver
genesymbol_syn
TLN
resolver
hgnc
HGNC:5348
resolver
uniprot
Q8N6I2
resolver
uniprot
Q9Y6F3
resolver
uniprot_entry
ICAM5_HUMAN
resolver
uniprot_entry
Q8N6I2_HUMAN
resolver
uniprot_sec
Q9Y6F3
resolver
amino_acid_sequence
MPGPSPGLRRALLGLWAALGLGLFGLSAVSQEPFWADLQPRVAFVERGGSLWLNCSTNCPRPERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCFFRCARRTLQARGLIRTFQRPDRVELMPLPPWQPVGENFTLSCRVPGAGPRASLTLTLLRGAQELIRRSFAGEPPRARGAVLTATVLARREDHGANFSCRAELDLRPHGLGLFENSSAPRELRTFSLSPDAPRLAAPRLLEVGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATATATASAEQEGARQLVCNVTLGGENRETRENVTIYSFPAPLLTLSEPSVSEGQMVTVTCAAGAQALVTLEGVPAAVPGQPAQLQLNATENDDRRSFFCDATLDVDGETLIKNRSAELRVLYAPRLDDSDCPRSWTWPEGPEQTLRCEARGNPEPSVHCARSDGGAVLALGLLGPVTRALSGTYRCKAANDQGEAVKDVTLTVEYAPALDSVGCPERITWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGLLRVAREHAGTYRCEATNPRGSAAKNVAVTVEYGPRFEEPSCPSNWTWVEGSGRLFSCEVDGKPQPSVKCVGSGGATEGVLLPLAPPDPSPRAPRIPRVLAPGIYVCNATNRHGSVAKTVVVSAESPPEMDESTCPSHQTWLEGAEASALACAARGRPSPGVRCSREGIPWPEQQRVSREDAGTYHCVATNAHGTDSRTVTVGVEYRPVVAELAASPPGGVRPGGNFTLTCRAEAWPPAQISWRAPPGALNIGLSSNNSTLSVAGAMGSHGGEYECAATNAHGRHARRITVRVAGPWLWVAVGGAAGGAALLAAGAGLAFYVQSTACKKGEYNVQEAESSGEAVCLNGAGGGAGGAAGAEGGPEAAGGAAESPAEGEVFAIQLTSA
uniprot
proteins
function
FUNCTION: Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring neuron cell-leukocyte adhesion (PubMed:8995416). Creates homophilic cell adhesion promoting dendritogenesis and arborization of hippocampal neurons (PubMed:10893271). {ECO:0000269|PubMed:10893271, ECO:0000269|PubMed:8995416}.
uniprot
proteins
mass_dalton
97116
uniprot
proteins
protein_family
ICAM family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
10893271
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15144186
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
18691975
uniprot
proteins
pubmed
25004970
uniprot
proteins
pubmed
8995416
uniprot
proteins
pubmed
9828136
uniprot
proteins
sequence_length
924
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q60625}; Single-pass membrane protein {ECO:0000255}. Cell projection {ECO:0000269|PubMed:10893271}. Cell projection, uropodium {ECO:0000269|PubMed:10893271}. Cell projection, dendritic spine membrane {ECO:0000250|UniProtKB:Q60625}. Note=At uropodium and cell-cell contact sites creates homophilic adhesion. {ECO:0000269|PubMed:10893271}.
uniprot
proteins
transmembrane_region
TRANSMEM 836..856; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins