NUDT8
entrez
254552
canonical
uniprot
Q8WV74
canonical
ensembl
ENSG00000167799
resolver
ensp
ENSP00000301490
resolver
ensp
ENSP00000365883
resolver
genesymbol
NUDT8
resolver
hgnc
HGNC:8055
resolver
uniprot
Q6ZW59
resolver
uniprot_entry
NUDT8_HUMAN
resolver
uniprot_sec
Q6ZW59
resolver
amino_acid_sequence
MLPDCLSAEGELRCRRLLAGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAGVGPLDPQSLRPNSEEVDEVFALPLAHLLQTQNQGYTHFCRGGHFRYTLPVFLHGPHRVWGLTAVITEFALQLLAPGTYQPRLAGLTCSGAEGLARPKQPLASPCQASSTPGLNKGL
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
ec_number
3.6.1.77
uniprot
proteins
function
FUNCTION: Acyl-CoA diphosphatase that mediates the hydrolysis of a wide range of CoA and CoA esters yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products (By similarity). Hydrolyzes short- and medium-chain acyl-CoAs, exhibiting the highest activity toward free CoA, hexanoyl-CoA, and octanoyl-CoA and the lowest activity against acetyl-CoA (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity). {ECO:0000250|UniProtKB:Q9CR24}.
uniprot
proteins
mass_dalton
25370
uniprot
proteins
protein_family
Nudix hydrolase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
236
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9CR24}.
uniprot
proteins