Srrm1
entrez
51796
canonical
uniprot
Q52KI8
canonical
ensembl
ENSMUSG00000028809
resolver
ensp
ENSMUSP00000081906
resolver
ensp
ENSMUSP00000101487
resolver
ensp
ENSMUSP00000125003
resolver
ensp
ENSMUSP00000187190
resolver
ensp
ENSMUSP00000187193
resolver
ensp
ENSMUSP00000187194
resolver
ensp
ENSMUSP00000187196
resolver
ensp
ENSMUSP00000187198
resolver
ensp
ENSMUSP00000187200
resolver
ensp
ENSMUSP00000187201
resolver
ensp
ENSMUSP00000187202
resolver
ensp
ENSMUSP00000187209
resolver
ensp
ENSMUSP00000187212
resolver
ensp
ENSMUSP00000187219
resolver
ensp
ENSMUSP00000330339
resolver
ensp
ENSMUSP00000330356
resolver
ensp
ENSMUSP00000330359
resolver
enst
ENSMUST00000084846
resolver
enst
ENSMUST00000105861
resolver
enst
ENSMUST00000136342
resolver
genesymbol
Srrm1
resolver
genesymbol_syn
Pop101
resolver
uniprot
A2A8V8
resolver
uniprot
A2A8V9
resolver
uniprot
E9PUK6
resolver
uniprot
E9QNW8
resolver
uniprot
O70495
resolver
uniprot
Q9CVG5
resolver
uniprot_entry
A2A8V8_MOUSE
resolver
uniprot_entry
A2A8V9_MOUSE
resolver
uniprot_entry
E9PUK6_MOUSE
resolver
uniprot_entry
SRRM1_MOUSE
resolver
uniprot_sec
E9QNW8
resolver
uniprot_sec
O70495
resolver
uniprot_sec
Q9CVG5
resolver
amino_acid_sequence
MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASLKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMKDSSVQEATSTSDILKAPKPEPVPEPKEPSPEKNSKKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPGRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSSPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMGKRWQSPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKTAMATQRNIRRVSKSPKADSLSRAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPAAAPEPRKETESEAEDDNLDDLERHLREKALRSMRKAQVSPQS
uniprot
proteins
function
FUNCTION: Part of pre- and post-splicing multiprotein mRNP complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity). Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates. {ECO:0000250|UniProtKB:Q8IYB3}.
uniprot
proteins
mass_dalton
106862
uniprot
proteins
post_translational_modification
PTM: Citrullinated by PADI4. {ECO:0000269|PubMed:24463520}.; PTM: Phosphorylated on multiple serine and threonine residues by DYRK3 during the G2-to-M transition, after the nuclear-envelope breakdown. Phosphorylation by DYRK3 promotes disassembly of nuclear speckles. {ECO:0000250|UniProtKB:Q8IYB3}.
uniprot
proteins
protein_family
Splicing factor SR family
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24463520
uniprot
proteins
sequence_length
946
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus matrix {ECO:0000255|PROSITE-ProRule:PRU00627}. Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00627}.
uniprot
proteins