LSM3
entrez
27258
canonical
uniprot
P62310
canonical
ensembl
ENSG00000170860
resolver
ensp
ENSP00000302160
resolver
enst
ENST00000306024
resolver
genesymbol
LSM3
resolver
hgnc
HGNC:17874
resolver
uniprot
Q6IAH0
resolver
uniprot
Q9Y4Z1
resolver
uniprot_entry
LSM3_HUMAN
resolver
uniprot_sec
Q6IAH0
resolver
uniprot_sec
Q9Y4Z1
resolver
amino_acid_sequence
MADDVDQQQTTNTVEEPLDLIRLSLDERIYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVRGDGVVLVAPPLRVG
uniprot
proteins
function
FUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). {ECO:0000269|PubMed:10523320, ECO:0000269|PubMed:28781166}.
uniprot
proteins
mass_dalton
11845
uniprot
proteins
protein_family
SnRNP Sm proteins family
uniprot
proteins
pubmed
10369684
uniprot
proteins
pubmed
10523320
uniprot
proteins
pubmed
11991638
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26912367
uniprot
proteins
pubmed
28781166
uniprot
proteins
sequence_length
102
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10523320, ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28781166}.
uniprot
proteins