Tmem214
entrez
68796
canonical
uniprot
Q8BM55
canonical
ensembl
ENSMUSG00000038828
resolver
ensp
ENSMUSP00000144615
resolver
genesymbol
Tmem214
resolver
uniprot
Q3TLH3
resolver
uniprot
Q3UPX9
resolver
uniprot
Q78HK3
resolver
uniprot
Q8R0D5
resolver
uniprot
Q8R237
resolver
uniprot
Q8VC05
resolver
uniprot_entry
TM214_MOUSE
resolver
uniprot_sec
Q3TLH3
resolver
uniprot_sec
Q3UPX9
resolver
uniprot_sec
Q78HK3
resolver
uniprot_sec
Q8R0D5
resolver
uniprot_sec
Q8R237
resolver
uniprot_sec
Q8VC05
resolver
amino_acid_sequence
MAARSAGSGGWEVVKRGRRPGASSGGRGGGGGSDRRALGEANGVLKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPAAESKKPINKKQPKKVTAVPSQNQKQGPFRRLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAVLQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKALSPFAIAYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWEHIPKKARKSLQETIQSLKVTNQELLKKGSGGSEHVLTCDTACKGLLQRARGPRPPWARLFLLLLVFAVGFLCHDLRSNSSLQASLTGRLLRSSGLLPVGQQVCARLSSYSLQSYNWLQETLPACGSHLLAVVQPSLQLAWTHIYAIFSFLSAHCASYLACFSDSLAGFFQRVQLPEALQQLFHALKELLLLFCHSVLLPTWHLLLAALAQVQEHCHEACRGDVTWDCIKTQLSRAAQWTWLCLQDVTVAFLDWALTMISQQ
uniprot
proteins
function
FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
76430
uniprot
proteins
protein_family
TMEM214 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
687
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 481..501; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 614..634; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins