Slc25a46
entrez
291709
canonical
uniprot
Q5EB62
canonical
ensembl
ENSRNOG00000017091
resolver
ensembl
ENSRNOG00055024484
resolver
ensembl
ENSRNOG00060026898
resolver
ensembl
ENSRNOG00065012186
resolver
ensp
ENSRNOP00000023032
resolver
ensp
ENSRNOP00055034330
resolver
ensp
ENSRNOP00060038730
resolver
ensp
ENSRNOP00065015180
resolver
enst
ENSRNOT00000023032
resolver
enst
ENSRNOT00055042096
resolver
enst
ENSRNOT00060046581
resolver
enst
ENSRNOT00065019807
resolver
genesymbol
Slc25a46
resolver
uniprot
B2RYK4
resolver
uniprot_entry
B2RYK4_RAT
resolver
uniprot_entry
S2546_RAT
resolver
amino_acid_sequence
MHPRRPEGFDGLGYRGGVRDDPAFGGPFHARSFGSGTELGHWVTTPPDIPGSRNLHWGEKSPSYGVPSAPPTLEGPAEEPFPGGGDGPRPGRSSEQLNRFAGFGIGLASLFTENVLAHPCIVLRRQCQVNYHARHYHLTPFSVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGIISEFTPLPREVSQKWNPKQIGEHLLLKCLTYMVAMPFYSASLIETVQSEIIRDNTGILECVKEGIGRVIGLGVPHSKRLLPLFSLIFPTVLHGVLHYIISSIIQKIVLLILKRKTCSSHLAESTSPMQNMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVLPINTQYEGMRDCVNTIKQEEGVFGFYKGFGAVIIQYTLHATILQITKIIYSTLLQNSI
uniprot
proteins
function
FUNCTION: Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization. May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane. Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission. {ECO:0000250|UniProtKB:Q96AG3}.
uniprot
proteins
mass_dalton
46210
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16949250
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
418
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q96AG3}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 103..123; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 382..402; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins