CEP128
entrez
145508
canonical
uniprot
Q6ZU80
canonical
ensembl
ENSG00000100629
resolver
ensp
ENSP00000281129
resolver
ensp
ENSP00000451137
resolver
ensp
ENSP00000451162
resolver
ensp
ENSP00000617753
resolver
ensp
ENSP00000751014
resolver
enst
ENST00000555529
resolver
genesymbol
CEP128
resolver
genesymbol_syn
C14orf145
resolver
genesymbol_syn
C14orf61
resolver
hgnc
HGNC:20359
resolver
uniprot
B9EK52
resolver
uniprot
G3V3A9
resolver
uniprot
Q86TS1
resolver
uniprot
Q86X97
resolver
uniprot
Q96ML4
resolver
uniprot_entry
CE128_HUMAN
resolver
uniprot_entry
G3V3A9_HUMAN
resolver
uniprot_entry
Q86TS1_HUMAN
resolver
uniprot_sec
B9EK52
resolver
uniprot_sec
Q86X97
resolver
uniprot_sec
Q96ML4
resolver
amino_acid_sequence
MAESSSESDHFRCRDRLSPWAARSTHRGTRSLPTVEVTEKVNTITSTLQDTSRNLRQVDQMLGRYREYSNGQAGAIEHLKESLEQSIDQLRSQRLLRNSGGRSISVTSLSASDLDGGTGSELHHFPPTSPLKDYGDPQGIKRMRSRTGVRFVQETDDMTQLHGFHQSLRDLSSEQIRLGDDFNRELSRRSRSDAETKRALEELTEKLNEAQKQEVVSDRVERRLQELEREMRTERELVERRQDQLGLMSLQLQEALKKQEAKADEHEGAIKNKLRQTETEKNQLEQELELSRRLLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSAMASELEEVKRCMERKDKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEEHLRRMEEARLQLKDQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRWLAESKTKLQWLCEELKERENREKNLRHQLMLCRQQLRNLTENKESELQCLFQQIERQEQLLDEIHREKRDLLEETQRKDEEMGSLQDRVIALETSTQVALDHLESVPEKLSLLEDFKDFRDSCSSSERTDGRYSKYRVRRNSLQHHQDDTKYRTKSFKGDRTFLEGSHTRGLDHSSSWQDHSRFLSSPRFSYVNSFTKRTVAPDSASNKEDATMNGTSSQPKKEEYGS
uniprot
proteins
function
FUNCTION: Is involved in the negative regulation of ciliogenesis and plays a role in spermatogenesis (PubMed:29514088, PubMed:35296684). Contributes to the regulation of the TGFB/BMP signaling pathway at the primary cilium, where it is required for ciliary localization of RAB11A, likely affecting the trafficking and regulation of TGFB/BMP pathway components (PubMed:29514088). Required, together with ODF2, for the formation of the subdistal appendage of the centriole (By similarity). {ECO:0000250|UniProtKB:Q8BI22, ECO:0000269|PubMed:29514088, ECO:0000269|PubMed:35296684}.
uniprot
proteins
mass_dalton
128015
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21399614
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
29514088
uniprot
proteins
pubmed
35296684
uniprot
proteins
sequence_length
1094
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:29514088, ECO:0000269|PubMed:35296684}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:29514088}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:21399614}. Note=Localized to the subdistal appendage of the mother centriole and the distal end of ciliary basal body. {ECO:0000269|PubMed:29514088}.
uniprot
proteins