CYP2A7
entrez
1549
canonical
uniprot
P20853
canonical
ensembl
ENSG00000198077
resolver
ensp
ENSP00000291764
resolver
ensp
ENSP00000301146
resolver
enst
ENST00000291764
resolver
enst
ENST00000301146
resolver
genesymbol
CYP2A7
resolver
hgnc
HGNC:2611
resolver
uniprot
F8W816
resolver
uniprot
Q13121
resolver
uniprot_entry
CP2A7_HUMAN
resolver
uniprot_entry
F8W816_HUMAN
resolver
uniprot_sec
Q13121
resolver
amino_acid_sequence
MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVVFATIPRNYTMSFLPR
uniprot
proteins
ec_number
1.14.14.1
uniprot
proteins
function
FUNCTION: Xenobiotic-metabolizing enzyme that can catalyze the hydroxylation of species-specific aromatic amine substrates (PubMed:38792050). Catalyzes the hydroxylation of diclofenac to a hydroxydiclofenac metabolite in vitro, suggesting a potential role in drug metabolism (PubMed:38792050). Does not metabolize nicotine, coumarin, or 7-ethoxycoumarin (PubMed:38792050). {ECO:0000269|PubMed:38792050}.
uniprot
proteins
mass_dalton
56425
uniprot
proteins
protein_family
Cytochrome P450 family
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
2322567
uniprot
proteins
pubmed
38792050
uniprot
proteins
pubmed
7668294
uniprot
proteins
sequence_length
494
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
uniprot
proteins