TMPRSS11E
entrez
28983
canonical
uniprot
Q9UL52
canonical
ensembl
ENSG00000087128
resolver
ensp
ENSP00000307519
resolver
enst
ENST00000305363
resolver
genesymbol
TMPRSS11E
resolver
genesymbol_syn
DESC1
resolver
genesymbol_syn
TMPRSS11E2
resolver
hgnc
HGNC:24465
resolver
uniprot
A6NL71
resolver
uniprot
Q14DC8
resolver
uniprot
Q6UW31
resolver
uniprot_entry
TM11E_HUMAN
resolver
uniprot_sec
A6NL71
resolver
uniprot_sec
Q14DC8
resolver
uniprot_sec
Q6UW31
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by SERPINA5. {ECO:0000269|PubMed:14696115}.
uniprot
proteins
amino_acid_sequence
MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. {ECO:0000250|UniProtKB:Q5S248}.
uniprot
proteins
mass_dalton
47696
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
11161383
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14696115
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17388811
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5S248}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q5S248}.; SUBCELLULAR LOCATION: [Transmembrane protease serine 11E catalytic chain]: Secreted {ECO:0000250|UniProtKB:Q5S248}. Note=Activated by cleavage and secreted. {ECO:0000250|UniProtKB:Q5S248}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..40; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins