Acaa1a
entrez
24157
canonical
uniprot
P21775
canonical
ensembl
ENSRNOG00000032908
resolver
ensp
ENSRNOP00000079249
resolver
ensp
ENSRNOP00000092329
resolver
enst
ENSRNOT00000103723
resolver
enst
ENSRNOT00000107742
resolver
genesymbol
Acaa1a
resolver
uniprot
A0A8I6AHC5
resolver
uniprot
A0A8I6G309
resolver
uniprot
Q5FVR9
resolver
uniprot_entry
A0A8I6AHC5_RAT
resolver
uniprot_entry
A0A8I6G309_RAT
resolver
uniprot_entry
THIKA_RAT
resolver
uniprot_sec
Q5FVR9
resolver
amino_acid_sequence
MSESVGRTSAMHRLQVVLGHLAGRPESSSALQAAPCSATFPQASASDVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN
uniprot
proteins
ec_number
2.3.1.155
uniprot
proteins
ec_number
2.3.1.16
uniprot
proteins
ec_number
2.3.1.9
uniprot
proteins
function
FUNCTION: Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs) (PubMed:9325339). Plays an important role in fatty acid peroxisomal beta-oxidation (PubMed:9325339). Catalyzes the cleavage of short, medium, long, and very long straight chain 3-oxoacyl-CoAs (PubMed:9325339). Medium chain straight 3-oxoacyl-CoAs are preferred substrates (PubMed:9325339). {ECO:0000269|PubMed:9325339}.
uniprot
proteins
mass_dalton
44839
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; peroxisomal fatty acid beta-oxidation. {ECO:0000269|PubMed:9325339}.
uniprot
proteins
protein_family
Thiolase family
uniprot
proteins
protein_family
Thiolase-like superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1680677
uniprot
proteins
pubmed
2210380
uniprot
proteins
pubmed
2307679
uniprot
proteins
pubmed
9325339
uniprot
proteins
sequence_length
434
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000269|PubMed:1680677, ECO:0000269|PubMed:2210380, ECO:0000269|PubMed:9325339}. Note=Transported into peroxisomes following association with PEX7. {ECO:0000250|UniProtKB:P09110}.
uniprot
proteins