Anxa13
entrez
69787
canonical
uniprot
Q99JG3
canonical
ensembl
ENSMUSG00000055114
resolver
ensp
ENSMUSP00000159441
resolver
enst
ENSMUST00000227274
resolver
genesymbol
Anxa13
resolver
uniprot_entry
ANX13_MOUSE
resolver
amino_acid_sequence
MGNRHAKERSHHHGFDADRDAKKLYKACKGMGTDEAAIIEVLSSRTSEERQQIKQKYKEKYGKDLEEVLNSELSGNFKKTALALLDRPNEYAARQLQKAMKGVGTDEAMLIEILCTRSNKEIVAIKEAYQRLFGRSLESDVKEDTSGNLRKILVSLLQASRDEEDTVDKELAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDMEETIEEETSGDLKKAYLTIVRCAQDLEGYFADLLYKAMKGMGTDEETLIRIIVTRAEVDLQGIKAKFQEKYQKSLSDMVHSDTSGDFRKLLVALLH
uniprot
proteins
function
FUNCTION: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup. {ECO:0000250|UniProtKB:P27216}.
uniprot
proteins
mass_dalton
35922
uniprot
proteins
protein_family
Annexin family
uniprot
proteins
pubmed
11961095
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30610115
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:30610115}. Cell membrane {ECO:0000250|UniProtKB:P27216}; Lipid-anchor {ECO:0000250|UniProtKB:P27216}. Cytoplasmic vesicle {ECO:0000269|PubMed:30610115}. Note=Myristoylation anchors the protein to the membrane, but the protein also displays calcium-dependent, reversible binding to lipid membranes. {ECO:0000250|UniProtKB:P27216}.
uniprot
proteins