Tprkb
entrez
69786
canonical
uniprot
Q8QZZ7
canonical
ensembl
ENSMUSG00000054226
resolver
ensp
ENSMUSP00000063927
resolver
ensp
ENSMUSP00000086998
resolver
ensp
ENSMUSP00000109381
resolver
ensp
ENSMUSP00000109382
resolver
ensp
ENSMUSP00000144160
resolver
ensp
ENSMUSP00000144660
resolver
ensp
ENSMUSP00000254320
resolver
ensp
ENSMUSP00000254321
resolver
ensp
ENSMUSP00000254323
resolver
ensp
ENSMUSP00000254332
resolver
enst
ENSMUST00000067137
resolver
enst
ENSMUST00000089570
resolver
enst
ENSMUST00000113752
resolver
enst
ENSMUST00000113753
resolver
enst
ENSMUST00000200680
resolver
enst
ENSMUST00000202803
resolver
genesymbol
Tprkb
resolver
uniprot
G3X9K8
resolver
uniprot_entry
G3X9K8_MOUSE
resolver
uniprot_entry
TPRKB_MOUSE
resolver
amino_acid_sequence
MQLSQQLDLFPECRVTLLLFKDVKNAGDLRKKAMEGSIDGSLINPNVIVDPFQILVAANKAVHLHRLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISETNTSVLIVYIEDGSKQVPQEHLVSQVEGQQVPLESLPEITRLSEVKKIYKLSSQEERIGTLLDAIICRMSTKDVL
uniprot
proteins
function
FUNCTION: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification. {ECO:0000250|UniProtKB:Q9Y3C4}.
uniprot
proteins
mass_dalton
19556
uniprot
proteins
protein_family
CGI121/TPRKB family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28805828
uniprot
proteins
sequence_length
175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9Y3C4}. Nucleus {ECO:0000250|UniProtKB:Q9Y3C4}.
uniprot
proteins