PROKR1
entrez
10887
canonical
uniprot
Q8TCW9
canonical
ensembl
ENSG00000169618
resolver
ensp
ENSP00000303775
resolver
enst
ENST00000303786
resolver
genesymbol
PROKR1
resolver
genesymbol_syn
GPR73
resolver
genesymbol_syn
PKR1
resolver
hgnc
HGNC:4524
resolver
uniprot
A5JUU2
resolver
uniprot
Q53QT9
resolver
uniprot
Q8NFJ7
resolver
uniprot_entry
PKR1_HUMAN
resolver
uniprot_sec
A5JUU2
resolver
uniprot_sec
Q53QT9
resolver
uniprot_sec
Q8NFJ7
resolver
amino_acid_sequence
METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
uniprot
proteins
function
FUNCTION: Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. {ECO:0000269|PubMed:18339712}.
uniprot
proteins
mass_dalton
44770
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11886876
uniprot
proteins
pubmed
12054613
uniprot
proteins
pubmed
12427552
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
18339712
uniprot
proteins
sequence_length
393
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 63..83; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 99..119; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 147..167; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 181..201; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 233..253; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 283..303; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 323..343; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins