TNFRSF10C
entrez
8794
canonical
uniprot
O14798
canonical
ensembl
ENSG00000173535
resolver
ensp
ENSP00000349324
resolver
ensp
ENSP00000547695
resolver
enst
ENST00000356864
resolver
enst
ENST00000877636
resolver
genesymbol
TNFRSF10C
resolver
genesymbol_syn
DCR1
resolver
genesymbol_syn
LIT
resolver
genesymbol_syn
TRAILR3
resolver
genesymbol_syn
TRID
resolver
hgnc
HGNC:11906
resolver
uniprot
O14755
resolver
uniprot
Q08AS6
resolver
uniprot
Q6FH98
resolver
uniprot
Q6UXM5
resolver
uniprot_entry
TR10C_HUMAN
resolver
uniprot_sec
O14755
resolver
uniprot_sec
Q08AS6
resolver
uniprot_sec
Q6FH98
resolver
uniprot_sec
Q6UXM5
resolver
amino_acid_sequence
MARIPKTLKFVVVIVAVLLPVLAYSATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSGEVQVSNCTSWDDIQCVEEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSPGTPAPAAEETMITSPGTPASSHYLSCTIVGIIVLIVLLIVFV
uniprot
proteins
function
FUNCTION: Acts as a receptor for the cytotoxic ligand TRAIL but does not contain the intracellular death domain required to initiate apoptosis. By competing with the functional TRAIL receptors TNFRSF10A and TNFRSF10B for ligand binding, it functions as a decoy receptor that protects cells from TRAIL-induced apoptosis. {ECO:0000269|PubMed:9242610, ECO:0000269|PubMed:9242611, ECO:0000269|PubMed:9314565, ECO:0000269|PubMed:9325248}.
uniprot
proteins
mass_dalton
27407
uniprot
proteins
post_translational_modification
PTM: N-glycosylated and O-glycosylated. {ECO:0000269|PubMed:9373179}.
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
9242610
uniprot
proteins
pubmed
9242611
uniprot
proteins
pubmed
9314565
uniprot
proteins
pubmed
9325248
uniprot
proteins
pubmed
9373179
uniprot
proteins
pubmed
9551946
uniprot
proteins
sequence_length
259
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:9314565}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:9242611, ECO:0000269|PubMed:9314565}.
uniprot
proteins