Chrna1
entrez
79557
canonical
uniprot
P25108
canonical
ensembl
ENSRNOG00000018286
resolver
ensembl
ENSRNOG00055023076
resolver
ensembl
ENSRNOG00060015213
resolver
ensembl
ENSRNOG00065017427
resolver
ensp
ENSRNOP00000024706
resolver
ensp
ENSRNOP00055032187
resolver
ensp
ENSRNOP00060020883
resolver
ensp
ENSRNOP00065023079
resolver
enst
ENSRNOT00000024706
resolver
enst
ENSRNOT00055039646
resolver
enst
ENSRNOT00060026084
resolver
enst
ENSRNOT00065029118
resolver
genesymbol
Chrna1
resolver
genesymbol_syn
Acra
resolver
uniprot_entry
ACHA_RAT
resolver
amino_acid_sequence
MELTAVLLLLGLCSAGTVLGSEHETRLVAKLFKDYSSVVRPVGDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPNTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTSLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHIMPEWVRKVFIDTIPNIMFFSTMKRPSRDKQEKRIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGVKYIAETMKSDQESNNASEEWKYVAMVMDHILLGVFMLVCLIGTLAVFAGRLIELHQQG
uniprot
proteins
function
FUNCTION: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. {ECO:0000250|UniProtKB:P02708}.
uniprot
proteins
mass_dalton
51867
uniprot
proteins
protein_family
Acetylcholine receptor (TC 1.A.9.1) subfamily
uniprot
proteins
protein_family
Alpha-1/CHRNA1 sub-subfamily
uniprot
proteins
protein_family
Ligand-gated ion channel (TC 1.A.9) family
uniprot
proteins
pubmed
1702709
uniprot
proteins
sequence_length
457
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic cell membrane {ECO:0000250|UniProtKB:P02708}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P02708}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 231..255; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 263..281; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 297..316; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 429..447; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins