Pih1d1
entrez
68845
canonical
uniprot
Q9CQJ2
canonical
ensembl
ENSMUSG00000003423
resolver
ensp
ENSMUSP00000082490
resolver
ensp
ENSMUSP00000103441
resolver
ensp
ENSMUSP00000148186
resolver
ensp
ENSMUSP00000353390
resolver
enst
ENSMUST00000085375
resolver
enst
ENSMUST00000107811
resolver
enst
ENSMUST00000210139
resolver
genesymbol
Pih1d1
resolver
genesymbol_syn
Nop17
resolver
uniprot
Q6NV90
resolver
uniprot_entry
PIHD1_MOUSE
resolver
uniprot_sec
Q6NV90
resolver
amino_acid_sequence
MADSTFLAPELSDTESMGEETVRFQELLLKASKELQQAQTARPDSTQIQPKPGFCVKTNSSEGKVFINICHSPSIPPPADVTEDELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSNFYLRMQNSDFLRELVVTIAREGLEDKYGLQLNPEWRMLKYRSFLGSISQQNIRSQQRPRIQELGTLDASGSLGTCHGPERPHLNLWLEAPDLLLAEVDLPKLDGAQGLALEIGENRLVIGGPQQLYHLDATVPLRINSEASRAAFHRRRKQLMVSMPLLTASS
uniprot
proteins
function
FUNCTION: Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (By similarity). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (By similarity). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (By similarity). Positively regulates the assembly and activity of the mTORC1 complex (By similarity). {ECO:0000250|UniProtKB:Q9NWS0}.
uniprot
proteins
mass_dalton
32209
uniprot
proteins
mutagenesis
MUTAGEN 57; /note="K->E: Abolishes binding to TELO2-phosphopeptide."; /evidence="ECO:0000269|PubMed:24794838"; MUTAGEN 64; /note="K->E: Abolishes binding to TELO2-phosphopeptide."; /evidence="ECO:0000269|PubMed:24794838"; MUTAGEN 153; /note="K->E: No effect on binding to TELO2-phosphopeptide."; /evidence="ECO:0000269|PubMed:24794838
uniprot
proteins
protein_family
PIH1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17335777
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24794838
uniprot
proteins
sequence_length
290
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17335777}.
uniprot
proteins