Ppp1r11
entrez
76497
canonical
uniprot
Q8K1L5
canonical
ensembl
ENSMUSG00000036398
resolver
ensp
ENSMUSP00000047202
resolver
ensp
ENSMUSP00000134685
resolver
enst
ENSMUST00000040402
resolver
enst
ENSMUST00000174711
resolver
genesymbol
Ppp1r11
resolver
genesymbol_syn
Tctex5
resolver
uniprot
A5A4Y9
resolver
uniprot
F7ARG3
resolver
uniprot
Q9DB02
resolver
uniprot_entry
A5A4Y9_MOUSE
resolver
uniprot_entry
F7ARG3_MOUSE
resolver
uniprot_entry
PP1RB_MOUSE
resolver
uniprot_sec
Q9DB02
resolver
amino_acid_sequence
MAETGAGISETVTETTVTETTVTETTEPENQSLIMKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCSHKHCVRGHRKGRRPTTPAPTPTTPPQPPDPSQPPPGPMQH
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (By similarity). {ECO:0000250|UniProtKB:O60927, ECO:0000269|PubMed:27805901}.
uniprot
proteins
mass_dalton
14544
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:O60927}.
uniprot
proteins
post_translational_modification
PTM: Auto-ubiquitinated. {ECO:0000250|UniProtKB:O60927}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
1718647
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27805901
uniprot
proteins
sequence_length
131
uniprot
proteins