Nacc2
entrez
67991
canonical
uniprot
Q9DCM7
canonical
ensembl
ENSMUSG00000026932
resolver
ensp
ENSMUSP00000028300
resolver
ensp
ENSMUSP00000109796
resolver
enst
ENSMUST00000028300
resolver
enst
ENSMUST00000114159
resolver
genesymbol
Nacc2
resolver
genesymbol_syn
Btbd14a
resolver
uniprot
Q3TZD3
resolver
uniprot
Q8VDF8
resolver
uniprot_entry
NACC2_MOUSE
resolver
uniprot_sec
Q3TZD3
resolver
uniprot_sec
Q8VDF8
resolver
amino_acid_sequence
MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGTVPPACFQQILSFCYTGKLTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAMIEDASSEPQSPCNQLQPATAAYVTSPSVPIPLLTRVKHEAMEMPPASGPGLASKRPLETGPRDGVAVATGAAGTPGTAPLKLPRVSYYGVPSLATLIPSIQQVPYPPGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKATGNYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRSVMGASAASLPLDPEFPSAAPQVFEQRIYAERRSDAATIVALRTDAVNVDLSTSANPAFEANEEVDGGGSVIQEVAAPEQLPADGQSSPQAFEQGNTSSSRPQTPVATATRRPEGTYAGTL
uniprot
proteins
function
FUNCTION: Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
63219
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
586
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Note=Predominantly associated with chromatin. {ECO:0000250}.
uniprot
proteins