DUSP11
entrez
8446
canonical
uniprot
O75319
canonical
ensembl
ENSG00000144048
resolver
ensembl
ENSG00000291483
resolver
ensp
ENSP00000272444
resolver
ensp
ENSP00000520634
resolver
genesymbol
DUSP11
resolver
genesymbol_syn
PIR1
resolver
hgnc
HGNC:3066
resolver
uniprot
B2RCT8
resolver
uniprot
C9JYA6
resolver
uniprot
Q6AI47
resolver
uniprot
Q9BWE3
resolver
uniprot_entry
DUS11_HUMAN
resolver
uniprot_sec
B2RCT8
resolver
uniprot_sec
C9JYA6
resolver
uniprot_sec
Q6AI47
resolver
uniprot_sec
Q9BWE3
resolver
amino_acid_sequence
MSQWHHPRSGWGRRRDFSGRSSAKKKGGNHIPERWKDYLPVGQRMPGTRFIAFKVPLQKSFEKKLAPEECFSPLDLFNKIREQNEELGLIIDLTYTQRYYKPEDLPETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHCTHGLNRTGYLICRYLIDVEGVRPDDAIELFNRCRGHCLERQNYIEDLQNGPIRKNWNSSVPRSSDFEDSAHLMQPVHNKPVKQGPRYNLHQIQGHSAPRHFHTQTQSLQQSVRKFSENPHVYQRHHLPPPGPPGEDYSHRRYSWNVKPNASRAAQDRRRWYPYNYSRLSYPACWEWTQ
uniprot
proteins
ec_number
3.1.3.-
uniprot
proteins
function
FUNCTION: Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism. {ECO:0000269|PubMed:10347225, ECO:0000269|PubMed:24447265, ECO:0000269|PubMed:9685386}.
uniprot
proteins
mass_dalton
38939
uniprot
proteins
mutagenesis
MUTAGEN 119; /note="H->G: No effect on phosphatase activity with ATP and ADP."; /evidence="ECO:0000269|PubMed:24447265"; MUTAGEN 152; /note="C->S: Loss of activity. No effect in RNA-binding."; /evidence="ECO:0000269|PubMed:10347225, ECO:0000269|PubMed:24447265, ECO:0000269|PubMed:9685386"; MUTAGEN 154; /note="H->A: Strongly decreases phosphatase activity with ATP and ADP."; /evidence="ECO:0000269|PubMed:24447265"; MUTAGEN 157; /note="N->A: Strongly decreases phosphatase activity with ATP and ADP."; /evidence="ECO:0000269|PubMed:24447265"; MUTAGEN 192; /note="R->K: Slightly decreases phosphatase activity with ATP. Strongly decreases phosphatase activity with ADP."; /evidence="ECO:0000269|PubMed:24447265
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
10347225
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
24447265
uniprot
proteins
pubmed
24531476
uniprot
proteins
pubmed
9685386
uniprot
proteins
sequence_length
330
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9685386}. Nucleus speckle {ECO:0000269|PubMed:9685386}.
uniprot
proteins