GMCL2
entrez
64396
canonical
uniprot
Q8NEA9
canonical
ensembl
ENSG00000244234
resolver
ensp
ENSP00000497178
resolver
enst
ENST00000463439
resolver
genesymbol
GMCL2
resolver
genesymbol_syn
GCL
resolver
genesymbol_syn
GMCL1L
resolver
genesymbol_syn
GMCL1P1
resolver
hgnc
HGNC:19717
resolver
uniprot
B2RDW6
resolver
uniprot
Q2VIQ8
resolver
uniprot
Q8TC88
resolver
uniprot
Q8TC89
resolver
uniprot_entry
GMCL2_HUMAN
resolver
uniprot_sec
B2RDW6
resolver
uniprot_sec
Q2VIQ8
resolver
uniprot_sec
Q8TC88
resolver
uniprot_sec
Q8TC89
resolver
amino_acid_sequence
MGSSSSRVLGQPRRALAQQEQGARARGSARRPDTGDDAASYGFCYCPGSHKRKRSSGACRYCDPDSHREEHEEEGDKQQPLLNTPARKKLRSTSKYIYQTLFLNGENSDIKICALGEEWRLHKIYLCQSGYFSSMFSGSWKESSMNIIELEIPDQNIDVDALQVAFGSLYRDDVLIKPSRVVAILAAACMLQLDGLIQQCGETMKETINVKTVCGYYTSVEIYGLDSVKKKCLEWLLNNLMTHQNVKLFKELGINVMKQLIGSSNLFVMQVEMDVYTTLKKWMFLQLVPSWNGSLKQLLTETDVWFSKQRKDFEGMAFLETEPGKPFVSVFRHLRLQYIISDLASARIIEQDGIVPSEWLSSVYKQQWFAMLRAEQDREVGPQEINKEDLEGNSMRCGRKLAKDGEYYWCWTGFNFGFDLLVIYTNGYIIFKRNTLNQPRSGSVSLRPRRSIAFRLRLASFDSSGKLVCSRTTGYQILILKKDQEQVVMNLDSRFLTFPLYICCNFLYISPEKGIENNRHPENPEN
uniprot
proteins
function
FUNCTION: Possible function in spermatogenesis. Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312). {ECO:0000250|UniProtKB:Q920G9, ECO:0000269|PubMed:14528312}.
uniprot
proteins
mass_dalton
60299
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:14528312}.
uniprot
proteins
pubmed
14528312
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16201836
uniprot
proteins
pubmed
16959974
uniprot
proteins
sequence_length
526
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus matrix {ECO:0000250|UniProtKB:Q920G9}.
uniprot
proteins