Cd59b
entrez
333883
canonical
uniprot
P58019
canonical
ensembl
ENSMUSG00000068686
resolver
ensp
ENSMUSP00000087912
resolver
ensp
ENSMUSP00000106760
resolver
ensp
ENSMUSP00000117553
resolver
ensp
ENSMUSP00000332695
resolver
ensp
ENSMUSP00000358442
resolver
enst
ENSMUST00000090429
resolver
enst
ENSMUST00000111130
resolver
enst
ENSMUST00000129749
resolver
genesymbol
Cd59b
resolver
uniprot
Q920G7
resolver
uniprot_entry
CD59B_MOUSE
resolver
uniprot_sec
Q920G7
resolver
amino_acid_sequence
MRAQRGLILLLLLLAVFCSTAVSLKCYNCLDPVSSCKINTTCSPNLDSCLYAVAGRQVYQQCWKLSDCNSNYIMSRLDVAGIQSKCCQWDLCNKNLDGLEEPNNAETSSLRKTALLGTSVLVAILKFCF
uniprot
proteins
function
FUNCTION: Potent inhibitor of the complement membrane attack complex (MAC) action, which protects self-cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins
mass_dalton
14227
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins
pubmed
10946279
uniprot
proteins
pubmed
11471050
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
129
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P13987}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:P13987}. Secreted {ECO:0000250|UniProtKB:P13987}. Note=Localizes to the cell surface. Soluble form found in a number of tissues. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins