Btf3
entrez
218490
canonical
uniprot
Q64152
canonical
ensembl
ENSMUSG00000021660
resolver
ensp
ENSMUSP00000022163
resolver
ensp
ENSMUSP00000118093
resolver
genesymbol
Btf3
resolver
uniprot
Q3UJR8
resolver
uniprot
Q64153
resolver
uniprot
Q6GU63
resolver
uniprot
Q6P3F3
resolver
uniprot_entry
BTF3_MOUSE
resolver
uniprot_entry
Q3UJR8_MOUSE
resolver
uniprot_sec
Q64153
resolver
uniprot_sec
Q6GU63
resolver
uniprot_sec
Q6P3F3
resolver
amino_acid_sequence
MRRTGAPTQADSRGRGRARGGWPGAEATPSLPLGGSRGRESQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDDDDEVPDLVENFDEASKNEAN
uniprot
proteins
function
FUNCTION: When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
22031
uniprot
proteins
protein_family
NAC-beta family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
7655515
uniprot
proteins
sequence_length
204
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus. Note=The heterodimer with NACA is cytoplasmic. {ECO:0000250}.
uniprot
proteins