Med21
entrez
108098
canonical
uniprot
Q9CQ39
canonical
ensembl
ENSMUSG00000030291
resolver
ensp
ENSMUSP00000032429
resolver
ensp
ENSMUSP00000145512
resolver
enst
ENSMUST00000032429
resolver
enst
ENSMUST00000204040
resolver
genesymbol
Med21
resolver
genesymbol_syn
Srb7
resolver
genesymbol_syn
Surb7
resolver
uniprot
Q921I5
resolver
uniprot_entry
MED21_MOUSE
resolver
uniprot_sec
Q921I5
resolver
amino_acid_sequence
MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFSNIQTAINKDQPANPTEEYAQLFAALIARTAKDIDVLIDSLPSEESTAALQAASLYKLEEENHEAATCLEDVVYRGDMLLEKIQSALADIAQSQLKTRSVTHSHSLPDS
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
15588
uniprot
proteins
protein_family
Mediator complex subunit 21 family
uniprot
proteins
pubmed
10500093
uniprot
proteins
pubmed
12037571
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
144
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins