OASL
entrez
8638
canonical
uniprot
Q15646
canonical
ensembl
ENSG00000135114
resolver
ensp
ENSP00000257570
resolver
ensp
ENSP00000341125
resolver
ensp
ENSP00000444127
resolver
ensp
ENSP00000479512
resolver
ensp
ENSP00000505685
resolver
enst
ENST00000680620
resolver
genesymbol
OASL
resolver
genesymbol_syn
TRIP14
resolver
hgnc
HGNC:8090
resolver
uniprot
A0A7P0T9H8
resolver
uniprot
B2RAZ2
resolver
uniprot
I1YDD2
resolver
uniprot
O75686
resolver
uniprot
Q17R95
resolver
uniprot
Q9Y6K6
resolver
uniprot
Q9Y6K7
resolver
uniprot_entry
A0A7P0T9H8_HUMAN
resolver
uniprot_entry
OASL_HUMAN
resolver
uniprot_sec
B2RAZ2
resolver
uniprot_sec
I1YDD2
resolver
uniprot_sec
O75686
resolver
uniprot_sec
Q17R95
resolver
uniprot_sec
Q9Y6K6
resolver
uniprot_sec
Q9Y6K7
resolver
amino_acid_sequence
MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKERPIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRARDIHLTVEQRGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDTLILSKKKGEALFPAS
uniprot
proteins
function
FUNCTION: Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. {ECO:0000269|PubMed:18931074, ECO:0000269|PubMed:20074559, ECO:0000269|PubMed:9826176}.
uniprot
proteins
mass_dalton
59226
uniprot
proteins
protein_family
2-5A synthase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14728690
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
17408844
uniprot
proteins
pubmed
18931074
uniprot
proteins
pubmed
19203244
uniprot
proteins
pubmed
19904482
uniprot
proteins
pubmed
20074559
uniprot
proteins
pubmed
21142819
uniprot
proteins
pubmed
22531715
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
7776974
uniprot
proteins
pubmed
9722630
uniprot
proteins
pubmed
9826176
uniprot
proteins
sequence_length
514
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform p56]: Nucleus, nucleolus. Cytoplasm.; SUBCELLULAR LOCATION: [Isoform p30]: Cytoplasm.
uniprot
proteins