Eef1akmt4-Ece2
entrez
110599584
canonical
uniprot
P0DPD9
canonical
ensembl
ENSMUSG00000115293
resolver
ensp
ENSMUSP00000078550
resolver
ensp
ENSMUSP00000113475
resolver
genesymbol
Eef1akmt4-Ece2
resolver
uniprot
E9QKA6
resolver
uniprot
Q14BY3
resolver
uniprot
Q80Z59
resolver
uniprot
Q80Z60
resolver
uniprot
Q9D8Q9
resolver
uniprot
Q9D928
resolver
uniprot_entry
EFCE2_MOUSE
resolver
uniprot_sec
E9QKA6
resolver
uniprot_sec
Q14BY3
resolver
uniprot_sec
Q80Z59
resolver
uniprot_sec
Q80Z60
resolver
uniprot_sec
Q9D8Q9
resolver
uniprot_sec
Q9D928
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by phosphoramidon. {ECO:0000250|UniProtKB:P0DPE2}.
uniprot
proteins
amino_acid_sequence
MASPRTPVSPPELPEKNFQYRQVQYWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGEPDPWNVSSEGVHTVDQVLSEVGFQKRTRQLFGSHTQLELVLAGLILVLAALLLGCLVALWVHRDPAHSTCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIGGWNITGPWDEDSFMDVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPAVDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
ec_number
3.4.24.71
uniprot
proteins
function
FUNCTION: Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity (By similarity). May play a role in amyloid-beta processing (PubMed:12464614). {ECO:0000250|UniProtKB:P0DPE2, ECO:0000269|PubMed:12464614}.
uniprot
proteins
mass_dalton
99480
uniprot
proteins
protein_family
Methyltransferase superfamily; Peptidase M13 family
uniprot
proteins
pubmed
10811845
uniprot
proteins
pubmed
12054617
uniprot
proteins
pubmed
12464614
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
881
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:P0DPE2}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P0DPE2}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:P0DPE2}.
uniprot
proteins
transmembrane_region
TRANSMEM 179..199; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins