Dhx30
entrez
72831
canonical
uniprot
Q99PU8
canonical
ensembl
ENSMUSG00000032480
resolver
ensp
ENSMUSP00000062622
resolver
ensp
ENSMUSP00000107622
resolver
ensp
ENSMUSP00000129174
resolver
ensp
ENSMUSP00000142489
resolver
ensp
ENSMUSP00000142549
resolver
ensp
ENSMUSP00000142659
resolver
ensp
ENSMUSP00000143371
resolver
ensp
ENSMUSP00000143616
resolver
ensp
ENSMUSP00000300999
resolver
ensp
ENSMUSP00000301005
resolver
enst
ENSMUST00000196171
resolver
genesymbol
Dhx30
resolver
genesymbol_syn
Helg
resolver
uniprot
A0A0G2JGL8
resolver
uniprot
Q3U4Z4
resolver
uniprot
Q3UFA0
resolver
uniprot
Q3UJS4
resolver
uniprot
Q91WA7
resolver
uniprot
Q99KN7
resolver
uniprot_entry
A0A0G2JGL8_MOUSE
resolver
uniprot_entry
DHX30_MOUSE
resolver
uniprot_sec
Q3U4Z4
resolver
uniprot_sec
Q3UFA0
resolver
uniprot_sec
Q3UJS4
resolver
uniprot_sec
Q91WA7
resolver
uniprot_sec
Q99KN7
resolver
amino_acid_sequence
MVTPVCNSSTWQPKDSSFLSWPEMFSLDSFRKDRTQHRQRQCKLPPPRLPPMCVNPAPGGTITRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPGGPAGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSSWISPELRLQSDDILPLGKDSGPLSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLREFRRALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLRGPCGSFDMRKTADD
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: RNA-dependent helicase (PubMed:25219788). Plays an important role in the assembly of the mitochondrial large ribosomal subunit (By similarity). Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). Associates with mitochondrial DNA (By similarity). Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD (PubMed:25219788). {ECO:0000250|UniProtKB:Q5BJS0, ECO:0000250|UniProtKB:Q7L2E3, ECO:0000269|PubMed:25219788}.
uniprot
proteins
mass_dalton
136668
uniprot
proteins
post_translational_modification
PTM: [Isoform 3]: Phosphorylated on Ser-15. {ECO:0000250|UniProtKB:Q7L2E3}.
uniprot
proteins
protein_family
DEAD box helicase family
uniprot
proteins
protein_family
DEAH subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25219788
uniprot
proteins
sequence_length
1217
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:25219788}. Mitochondrion {ECO:0000250|UniProtKB:Q7L2E3}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250|UniProtKB:Q7L2E3}. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. Relocalizes to stress granules upon heat stress. {ECO:0000250|UniProtKB:Q7L2E3}.
uniprot
proteins