Decr1
entrez
67460
canonical
uniprot
Q9CQ62
canonical
ensembl
ENSMUSG00000028223
resolver
ensp
ENSMUSP00000029877
resolver
enst
ENSMUST00000029877
resolver
genesymbol
Decr1
resolver
uniprot
Q4FJK0
resolver
uniprot
Q9DCI7
resolver
uniprot_entry
DECR_MOUSE
resolver
uniprot_entry
Q4FJK0_MOUSE
resolver
uniprot_sec
Q9DCI7
resolver
amino_acid_sequence
MALLGRAFFAGVSRLPCDPGPQRFFSFGTKTLYQSKDAPQSKFFQPVLKPMLPPDAFQGKVAFITGGGTGLGKAMTTFLSTLGAQCVIASRNIDVLKATAEEISSKTGNKVHAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLTPNGWKTITDIVLNGTAYVTLEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGRFEKEMIDRIPCGRLGTMEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDIIEGLIRKTKGS
uniprot
proteins
ec_number
1.3.1.124
uniprot
proteins
function
FUNCTION: Auxiliary enzyme in the beta-oxidation of mono- and polyunsaturated fatty acids. Together with the Enoyl-CoA delta isomerase 1 (ECI1) and the Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase (ECH1) they allow reentrance of the enoyl-CoA into the beta-oxidation cycle. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Acts primarily on polyunsaturated fatty acids. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Based on its established catalytic mechanism, it is predicted to act also on other fatty acids besides those tested experimentally. {ECO:0000250|UniProtKB:Q16698}.
uniprot
proteins
mass_dalton
36214
uniprot
proteins
protein_family
2
uniprot
proteins
protein_family
4-dienoyl-CoA reductase subfamily
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q16698}.
uniprot
proteins