Mrs2
entrez
79032
canonical
uniprot
Q9ET09
canonical
ensembl
ENSRNOG00000017545
resolver
ensembl
ENSRNOG00055005275
resolver
ensembl
ENSRNOG00060024010
resolver
ensembl
ENSRNOG00065023590
resolver
ensp
ENSRNOP00000023787
resolver
genesymbol
Mrs2
resolver
genesymbol_syn
Mrs2l
resolver
genesymbol_syn
Rpt
resolver
uniprot
Q4FZY6
resolver
uniprot
Q5XIW5
resolver
uniprot
Q9ET07
resolver
uniprot
Q9ET08
resolver
uniprot_entry
MRS2_RAT
resolver
uniprot_sec
Q4FZY6
resolver
uniprot_sec
Q5XIW5
resolver
uniprot_sec
Q9ET07
resolver
uniprot_sec
Q9ET08
resolver
activity_regulation
ACTIVITY REGULATION: May be regulated by calcium ions. {ECO:0000250|UniProtKB:Q9HD23}.
uniprot
proteins
amino_acid_sequence
MECLRYLPRLLPRAAQSRSALCMAAVRLSLAACCGRATPLTSGSQKAPSTPRTAGDVYRFRTSDASQATLASVAQVFAVTKFDKEGNVTSFERKKTELYHELALQARDLRFQHVMSITTRNNRIIMRMEYLKAVITPEYLLILDYRNLNLEHWLFRELPSQLAGEGQLVTYPLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHVLLQNGKSLSELETDIKIFKESILELLDEEEMLEELCLTKWSDPHVFEQSSTGIDHAEEMELLLENYYRLADDLSNEARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFGMNLESSLEEDHRVFWLITGIMFMGSGLIWRRLLSFLGRQLEAPLPPVMASLPKKTLLADRRMDVKNSLRPEGLGAGRTILASR
uniprot
proteins
function
FUNCTION: Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix and regulates magnesium metabolism (By similarity). Also permeable to calcium, sodium and potassium ions (By similarity). Required for normal expression of the mitochondrial respiratory complex I subunits (By similarity). May play a role in maintaining the inner mitochondrial membrane potential (By similarity). {ECO:0000250|UniProtKB:Q9HD23}.
uniprot
proteins
mass_dalton
49365
uniprot
proteins
protein_family
CorA metal ion transporter (MIT) (TC 1.A.35) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
434
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9HD23}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9HD23}.
uniprot
proteins
transmembrane_region
TRANSMEM 331..350; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q9HD23"; TRANSMEM 362..392; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q9HD23
uniprot
proteins