Artn
entrez
11876
canonical
uniprot
Q9Z0L2
canonical
ensembl
ENSMUSG00000028539
resolver
ensp
ENSMUSP00000064521
resolver
ensp
ENSMUSP00000095526
resolver
ensp
ENSMUSP00000310002
resolver
ensp
ENSMUSP00000310003
resolver
genesymbol
Artn
resolver
uniprot
Q3SXF4
resolver
uniprot
Q3SXF5
resolver
uniprot_entry
ARTN_MOUSE
resolver
uniprot_sec
Q3SXF4
resolver
uniprot_sec
Q3SXF5
resolver
amino_acid_sequence
MELGLAEPTALSHCLRPRWQSAWWPTLAVLALLSCVTEASLDPMSRSPAARDGPSPVLAPPTDHLPGGHTAHLCSERTLRPPPQSPQPAPPPPGPALQSPPAALRGARAARAGTRSSRARTTDARGCRLRSQLVPVSALGLGHSSDELIRFRFCSGSCRRARSQHDLSLASLLGAGALRSPPGSRPISQPCCRPTRYEAVSFMDVNSTWRTVDHLSATACGCLG
uniprot
proteins
function
FUNCTION: Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain (By similarity). Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor (PubMed:15204970). Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue (PubMed:17322904). {ECO:0000250|UniProtKB:Q5T4W7, ECO:0000269|PubMed:15204970, ECO:0000269|PubMed:17322904}.
uniprot
proteins
mass_dalton
23726
uniprot
proteins
protein_family
GDNF subfamily
uniprot
proteins
protein_family
TGF-beta family
uniprot
proteins
pubmed
15204970
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17322904
uniprot
proteins
pubmed
9883723
uniprot
proteins
sequence_length
224
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15204970}.
uniprot
proteins