Esrp2
entrez
77411
canonical
uniprot
Q8K0G8
canonical
ensembl
ENSMUSG00000084128
resolver
ensp
ENSMUSP00000111639
resolver
ensp
ENSMUSP00000206729
resolver
enst
ENSMUST00000115979
resolver
genesymbol
Esrp2
resolver
genesymbol_syn
Rbm35b
resolver
uniprot
Q8CEK2
resolver
uniprot_entry
ESRP2_MOUSE
resolver
uniprot_sec
Q8CEK2
resolver
amino_acid_sequence
MTPPPPPPPPPGPDPAVDSATDPCPEPQSLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAALSPQCREASGLSADSLARAESLDKVLQQFSQLVSGDVALLGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHMQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGSNGQLFSKPEVVKQKYETGPCSKADVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPTDVLGFLGPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYAASPLLPTLTAPLLPIPFPLAGGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMMSVERALAAAQRCHKKMMKERYVEVVPCSTEEMSRVLMGGSLSRSGLSPPPCKLPCLSPPTYATFQATPALIPTETTALYPSSALLPAARVPAAATPLAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPTALASTPTTMLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLAPDDYTTLMPVGDPPRTVLQAPKEWVCL
uniprot
proteins
function
FUNCTION: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
77361
uniprot
proteins
protein_family
ESRP family
uniprot
proteins
pubmed
14681479
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
717
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins