Araf
entrez
64363
canonical
uniprot
P14056
canonical
ensembl
ENSRNOG00000010838
resolver
ensp
ENSRNOP00000048890
resolver
genesymbol
Araf
resolver
genesymbol_syn
A-raf
resolver
genesymbol_syn
Araf1
resolver
uniprot
A6JZS1
resolver
uniprot
Q6P9W2
resolver
uniprot_entry
A6JZS1_RAT
resolver
uniprot_entry
ARAF_RAT
resolver
uniprot_sec
Q6P9W2
resolver
amino_acid_sequence
MEPPRGPPASGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSIQDLSGGSRQQEVPSNLSVNELLTPQGPSPFTQQRDQEHFSFPAPANPPLQRIRSTSTPNVHMVSTTAPMDSSLMQFTAQSFSTDAAGRGGDGAPRGSPSPASVSSGRKSPHSKLPAEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade (By similarity). Phosphorylates PFKFB2 (By similarity). {ECO:0000250|UniProtKB:P10398}.
uniprot
proteins
mass_dalton
67551
uniprot
proteins
post_translational_modification
PTM: Dephosphorylation by the SHOC2-MRAS-PP1c (SMP) complex consisting of SHOC2, GTP-bound M-Ras/MRAS and the catalytic subunit of protein phosphatase 1 (PPP1CA, PPP1CB or PPP1CC); this relieves inactivation and stimulates kinase activity. {ECO:0000250|UniProtKB:P10398}.
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
RAF subfamily
uniprot
proteins
protein_family
TKL Ser/Thr protein kinase family
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
3449797
uniprot
proteins
sequence_length
604
uniprot
proteins