HMGN3
entrez
9324
canonical
uniprot
Q15651
canonical
ensembl
ENSG00000118418
resolver
ensp
ENSP00000275036
resolver
ensp
ENSP00000341267
resolver
ensp
ENSP00000482613
resolver
ensp
ENSP00000515488
resolver
ensp
ENSP00000516483
resolver
ensp
ENSP00000516488
resolver
ensp
ENSP00000565509
resolver
ensp
ENSP00000565514
resolver
ensp
ENSP00000740152
resolver
enst
ENST00000620514
resolver
enst
ENST00000703810
resolver
enst
ENST00000706657
resolver
genesymbol
HMGN3
resolver
genesymbol_syn
TRIP7
resolver
hgnc
HGNC:12312
resolver
uniprot
A0A087WZE9
resolver
uniprot
A0A994J3W4
resolver
uniprot
A0A9L9PXC9
resolver
uniprot
B2RD37
resolver
uniprot
Q5HYD3
resolver
uniprot
Q7RTT0
resolver
uniprot
Q969M5
resolver
uniprot
Q9BZT7
resolver
uniprot_entry
A0A087WZE9_HUMAN
resolver
uniprot_entry
A0A994J3W4_HUMAN
resolver
uniprot_entry
A0A9L9PXC9_HUMAN
resolver
uniprot_entry
HMGN3_HUMAN
resolver
uniprot_sec
B2RD37
resolver
uniprot_sec
Q5HYD3
resolver
uniprot_sec
Q7RTT0
resolver
uniprot_sec
Q969M5
resolver
uniprot_sec
Q9BZT7
resolver
amino_acid_sequence
MPKRKSPENTEGKDGSKVTKQEPTRRSARLSAKPAPPKPEPKPRKTSAKKEPGAKISRGAKGKKEEKQEAGKEGTAPSENGETKAEEAQKTESVDNEGE
uniprot
proteins
function
FUNCTION: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
10666
uniprot
proteins
protein_family
HMGN family
uniprot
proteins
pubmed
11356838
uniprot
proteins
pubmed
12033773
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
33468658
uniprot
proteins
pubmed
7776974
uniprot
proteins
sequence_length
99
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins