AP5S1
entrez
55317
canonical
uniprot
Q9NUS5
canonical
ensembl
ENSG00000125843
resolver
ensp
ENSP00000368886
resolver
ensp
ENSP00000405487
resolver
ensp
ENSP00000481750
resolver
ensp
ENSP00000520567
resolver
ensp
ENSP00000540832
resolver
ensp
ENSP00000540833
resolver
ensp
ENSP00000540834
resolver
ensp
ENSP00000597200
resolver
ensp
ENSP00000611829
resolver
enst
ENST00000379567
resolver
enst
ENST00000455742
resolver
enst
ENST00000615891
resolver
enst
ENST00000620777
resolver
enst
ENST00000870773
resolver
enst
ENST00000870774
resolver
enst
ENST00000870775
resolver
enst
ENST00000927141
resolver
enst
ENST00000941770
resolver
genesymbol
AP5S1
resolver
genesymbol_syn
C20orf29
resolver
hgnc
HGNC:15875
resolver
uniprot
B3KSD0
resolver
uniprot
D3DVY7
resolver
uniprot_entry
AP5S1_HUMAN
resolver
uniprot_sec
B3KSD0
resolver
uniprot_sec
D3DVY7
resolver
amino_acid_sequence
MVHAFLIHTLRAPNTEDTGLCRVLYSCVFGAEKSPDDPRPHGAERDRLLRKEQILAVARQVESMCRLQQQASGRPPMDLQPQSSDEQVPLHEAPRGAFRLAAENPFQEPRTVVWLGVLSLGFALVLDAHENLLLAEGTLRLLTRLLLDHLRLLAPSTSLLLRADRIEGILTRFLPHGQLLFLNDQFVQGLEKEFSAAWPR
uniprot
proteins
function
FUNCTION: As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862, it is required for efficient homologous recombination DNA double-strand break repair. {ECO:0000269|PubMed:20613862, ECO:0000269|PubMed:22022230}.
uniprot
proteins
mass_dalton
22522
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20613862
uniprot
proteins
pubmed
22022230
uniprot
proteins
sequence_length
200
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:22022230}. Late endosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}. Lysosome membrane {ECO:0000305|PubMed:22022230}; Peripheral membrane protein {ECO:0000305|PubMed:22022230}; Cytoplasmic side {ECO:0000305|PubMed:22022230}.
uniprot
proteins