Serpind1
entrez
15160
canonical
uniprot
P49182
canonical
ensembl
ENSMUSG00000022766
resolver
ensp
ENSMUSP00000023450
resolver
ensp
ENSMUSP00000156303
resolver
enst
ENSMUST00000023450
resolver
enst
ENSMUST00000231884
resolver
genesymbol
Serpind1
resolver
genesymbol_syn
Hcf2
resolver
genesymbol_syn
Hcii
resolver
uniprot_entry
HEP2_MOUSE
resolver
amino_acid_sequence
MKHPLCTLLSLITFMCIGSKGLAEQLTNENLTTSFLPANFHKENTVTNDWIPEGEEDEDYLDLEKLLGEDDDYIYIIDAVSPTDSESSAGNILQLFQGKSRIQRLNILNAKFAFNLYRVLKDQATTSDNLFIAPVGISTAMGMISLGLRGETHEEVHSVLHFRDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLRSVNGLYIQKQFPIREDFKAAMREFYFAEAQEANFPDPAFISKANNHILKLTKGLIKEALENIDPATQMLILNCIYFKGTWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKLFNKNGNMSGISDQRIAIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQVRFTVDRPFLFLVYEHRTSCLLFMGKVTNPAKS
uniprot
proteins
function
FUNCTION: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.
uniprot
proteins
mass_dalton
54497
uniprot
proteins
post_translational_modification
PTM: N-glycosylated; different glycan composition appears to lead to two forms of this protein (68 and 72 kDa). {ECO:0000269|PubMed:16944957}.
uniprot
proteins
protein_family
Serpin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16944957
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7908224
uniprot
proteins
sequence_length
478
uniprot
proteins