Ctu1
entrez
292847
canonical
uniprot
B1WBV0
canonical
ensembl
ENSRNOG00000018334
resolver
ensembl
ENSRNOG00055005677
resolver
ensembl
ENSRNOG00060010946
resolver
ensembl
ENSRNOG00065028843
resolver
ensp
ENSRNOP00000024690
resolver
ensp
ENSRNOP00055006987
resolver
ensp
ENSRNOP00060014399
resolver
ensp
ENSRNOP00065040866
resolver
enst
ENSRNOT00000024690
resolver
enst
ENSRNOT00055009144
resolver
enst
ENSRNOT00060018515
resolver
enst
ENSRNOT00065049778
resolver
genesymbol
Ctu1
resolver
genesymbol_syn
Atpbd3
resolver
genesymbol_syn
Ncs6
resolver
uniprot_entry
CTU1_RAT
resolver
amino_acid_sequence
MPAPTCFSCHKARAALRRPRSGQALCGPCFCAAFEAEVLRTVLAGHLLPQGAVVAVGASGGKDSTVLAHVLRELAPRLGITLHLVAVDEGIGGYRDAALEAVRSQAARWELPLTIVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGARLVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGVLGSTGEGCALPRCRPLQFASQKEVVLYAHFRHLRYFSEECVYAPEAFRGHARDLLKLLEAARPSAVLDLVHSAERLALAPAAKPPPPGTCSRCGALASNKLCQACALLDGLNRGLPRLAIGKGRRVLQVEPPPLGNPSRVTSDPVALPEPCTCKQSKDESNPCGNGGDRAGATCVSKSDLSPVAE
uniprot
proteins
ec_number
2.7.7.-
uniprot
proteins
function
FUNCTION: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. {ECO:0000255|HAMAP-Rule:MF_03053}.
uniprot
proteins
mass_dalton
40242
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. {ECO:0000255|HAMAP-Rule:MF_03053}.
uniprot
proteins
protein_family
CTU1/NCS6/ATPBD3 subfamily
uniprot
proteins
protein_family
TtcA family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
382
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03053}.
uniprot
proteins