Slc67a1
entrez
309131
canonical
uniprot
Q6AY78
canonical
ensembl
ENSRNOG00000020562
resolver
ensp
ENSRNOP00000027925
resolver
enst
ENSRNOT00000027925
resolver
genesymbol
Slc67a1
resolver
genesymbol_syn
Orctl2
resolver
genesymbol_syn
Slc22a18
resolver
genesymbol_syn
Tssc5
resolver
uniprot
A0A0G2JSS3
resolver
uniprot_entry
S67A1_RAT
resolver
uniprot_sec
A0A0G2JSS3
resolver
amino_acid_sequence
MSGQLPSSMVALPRQGIIILTYVLAALELTCLFMQFSIIPYLSRTLGLDSVSFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAASALYLLLVASCSPALPGVFLLFASRLPAALMHTLPAAQMVITDLTAPTKRPTALSRLGLCFGIGVIFGSLLGGTLSTAYGIQCPAFLAFVVTLLGAVLSFTCIPVTTKEASVQSAHQGGTSVFDLKAISRLLLLPRVLPVFLVKVISGFPSGLFMVMFSIISMDFFQLEAAQAGYLMSFFGILQMMIQGLVIGRLSTRFPEEALLRSSVLVFAVVGLGMALMSNVFHFCLLLPGLVFSLCALNIVTDSMLTKAVSASDTGTMLGLCASVHPLTRTVGPTLGGLLYRSYGVSILGHVQLMVNLLVLLVLWKKPLSQKGDKAR
uniprot
proteins
function
FUNCTION: May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney (By similarity). Plays a role in the regulation of lipid metabolism (By similarity). {ECO:0000250|UniProtKB:Q78KK3, ECO:0000250|UniProtKB:Q96BI1}.
uniprot
proteins
mass_dalton
43818
uniprot
proteins
protein_family
Major facilitator (TC 2.A.1) superfamily
uniprot
proteins
protein_family
Organic cation transporter (TC 2.A.1.19) family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
412
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:Q96BI1}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96BI1}. Note=Localized at the apical membrane surface of renal proximal tubules. {ECO:0000250|UniProtKB:Q96BI1}.
uniprot
proteins
transmembrane_region
TRANSMEM 16..36; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 51..71; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 148..168; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 176..196; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 264..284; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 294..314; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 316..336; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 380..400; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins