Fut9
entrez
84597
canonical
uniprot
Q99JB3
canonical
ensembl
ENSRNOG00000070149
resolver
ensembl
ENSRNOG00055010194
resolver
ensembl
ENSRNOG00060013840
resolver
ensembl
ENSRNOG00065005705
resolver
ensp
ENSRNOP00000087361
resolver
ensp
ENSRNOP00000100992
resolver
ensp
ENSRNOP00000101275
resolver
ensp
ENSRNOP00000105382
resolver
ensp
ENSRNOP00000108699
resolver
ensp
ENSRNOP00000109892
resolver
ensp
ENSRNOP00055013853
resolver
ensp
ENSRNOP00060018794
resolver
ensp
ENSRNOP00065006000
resolver
enst
ENSRNOT00000113229
resolver
enst
ENSRNOT00000127777
resolver
enst
ENSRNOT00000155901
resolver
enst
ENSRNOT00000160477
resolver
enst
ENSRNOT00000166081
resolver
enst
ENSRNOT00000169939
resolver
enst
ENSRNOT00055017213
resolver
enst
ENSRNOT00060023642
resolver
enst
ENSRNOT00065008515
resolver
genesymbol
Fut9
resolver
uniprot_entry
FUT9_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Activated by Mn2+. {ECO:0000250|UniProtKB:Q9Y231}.
uniprot
proteins
amino_acid_sequence
MTSTSKGILRPFLIVCIILGCFVACLLIYIKPTNSWVFSPMESASSVLKMKNFFSRKTDYFNETTILVWVWPFGQTFDLTSCQAMFNIQGCHLTTDRSLYNKSHAVLIHHRDISWDLTNLPQQARPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFLTVSTSPFVFEVPSKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQAFGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSRENYENYIPADSFIHVEDFNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN
uniprot
proteins
ec_number
2.4.1.152
uniprot
proteins
function
FUNCTION: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, beta-D-Gal-(1->4)-beta-D-GlcNAc-) glycan attached to glycolipids and N- or O-linked glycoproteins. Fucosylates distal type 2 LacNAc and its fucosylated (H-type 2 LacNAc) and sialylated (sialyl-type 2 LacNAc) derivatives to form Lewis x (Lex) (CD15) and Lewis y (Ley) antigenic epitopes involved in cell adhesion and differentiation (By similarity) (PubMed:11020213, PubMed:11675393). Generates Lex epitopes in the brain, presumably playing a role in the maintenance of neuronal stemness and neurite outgrowth in progenitor neural cells (By similarity). Fucosylates the internal type 2 LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (By similarity). Can also modify milk oligosaccharides in particular type 2 tetrasaccharide LNnT (By similarity). {ECO:0000250|UniProtKB:O88819, ECO:0000250|UniProtKB:Q9Y231, ECO:0000269|PubMed:11020213, ECO:0000269|PubMed:11675393}.
uniprot
proteins
mass_dalton
42037
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:O88819, ECO:0000250|UniProtKB:Q9Y231}.; PATHWAY: Glycolipid biosynthesis. {ECO:0000250|UniProtKB:O88819}.
uniprot
proteins
post_translational_modification
PTM: N-glycosylated with complex-type N-glycans. {ECO:0000250|UniProtKB:Q9Y231}.
uniprot
proteins
protein_family
Glycosyltransferase 10 family
uniprot
proteins
pubmed
11020213
uniprot
proteins
pubmed
11675393
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q9Y231}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q6P4F1}. Golgi apparatus membrane {ECO:0000250|UniProtKB:O88819}.
uniprot
proteins
transmembrane_region
TRANSMEM 12..32; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins