Lrguk
entrez
74354
canonical
uniprot
Q9D5S7
canonical
ensembl
ENSMUSG00000056215
resolver
ensp
ENSMUSP00000065146
resolver
ensp
ENSMUSP00000153993
resolver
ensp
ENSMUSP00000159470
resolver
ensp
ENSMUSP00000212397
resolver
enst
ENSMUST00000070189
resolver
enst
ENSMUST00000228187
resolver
enst
ENSMUST00000240538
resolver
genesymbol
Lrguk
resolver
uniprot
A0A2I3BQA5
resolver
uniprot
A0A8Q0LUS2
resolver
uniprot_entry
A0A2I3BQA5_MOUSE
resolver
uniprot_entry
A0A8Q0LUS2_MOUSE
resolver
uniprot_entry
LRGUK_MOUSE
resolver
amino_acid_sequence
MAAFERNPSRWKGTRFRRGLGASRIAAQAILSLTEKQSQGRWPSFPLGLKSKGTFRSASSYLLHQLIHRSHEAEAEQEEKQQEDGESEESEESEMQNLEDKYDGILREETVAEAITGLGWSGRGTEQVYLNLNLSHCELVDISILCGYVHLQKLNLSGNRIEDLSCVSCMPYLLELNASQNKLTTFFNFKPPQNLKKVDFSSNLISEMYDLSAYHTLTQLILDNNEIEEITGLENCISLTHLSLAGNKITTIKGLGTLPIKVLSLSNNMIETITGLEELKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIKELSEIEYIENLPILRVLNLLRNPIQTKPEYWFFVIYMLLRLTELDQQKIKVEEKVFAVNKYDPPPEVVAVQDHMTHVVNSMSQPQRIWDSTLPSLDAPYPMLILTGPAACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQEVFDEMLNMGKFILTFNYGNHNYGLNRDTIEGIARDGLASCIHMELEGVRSLKYSYFEPRYILVVPMDKEKYEGYLRRKGLFSRAEIEIAVSRVDLYVKVNQKYPGYFDAVINADDMDIAYQKLSELIREYLGLTETAAKTLAPTADTKTSYLKCEDYSRKSSTVEFLDSTDRNYFTKLWAKLSSKKSPVERESLHRQHEAARQALMGKTPRDHTLLFQRGPVPIPTVSGQQYFATIDELQKTFELSDDLFKTPSGTYPETSKDSNISKRYSTYFHTCPWSKELPFQLPEGGISSRPGSAGSDEVDGALKALRVASSMQEKVAQHKRLSAITIMDPGSNTKPTLPPIPHGRR
uniprot
proteins
function
FUNCTION: Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development (PubMed:25781171). Not essential for primary cilium biogenesis (PubMed:28003339). {ECO:0000269|PubMed:25781171, ECO:0000269|PubMed:28003339}.
uniprot
proteins
mass_dalton
93190
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
25781171
uniprot
proteins
pubmed
28003339
uniprot
proteins
sequence_length
820
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:25781171, ECO:0000269|PubMed:28003339}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:28003339}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:28003339}. Note=Localizes to the acrosome and acroplaxome in round spermatids. Localizes to the manchette during spermiogenesis. Also found in the basal body of elongating spermatids, and in primary cilia of somatic cells. {ECO:0000269|PubMed:25781171, ECO:0000269|PubMed:28003339}.
uniprot
proteins