ITGB5
entrez
3693
canonical
uniprot
P18084
canonical
ensembl
ENSG00000082781
resolver
ensp
ENSP00000296181
resolver
ensp
ENSP00000575085
resolver
ensp
ENSP00000605954
resolver
enst
ENST00000296181
resolver
genesymbol
ITGB5
resolver
hgnc
HGNC:6160
resolver
uniprot
B0LPF8
resolver
uniprot
B2RD70
resolver
uniprot
L7RT22
resolver
uniprot_entry
ITB5_HUMAN
resolver
uniprot_entry
L7RT22_HUMAN
resolver
uniprot_sec
B0LPF8
resolver
uniprot_sec
B2RD70
resolver
amino_acid_sequence
MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILDGDSKNIIQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGDTASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSARCNGSGTYVCGLCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCSCFESEFGKIYGPFCECDNFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDISTCRGRDGQICSERGHCLCGQCQCTEPGAFGEMCEKCPTCPDACSTKRDCVECLLLHSGKPDNQTCHSLCRDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFTYVELPSGKSNLTVLREPECGNTPNAMTILLAVVGSILLVGLALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFTFNKFNKSYNGTVD
uniprot
proteins
function
FUNCTION: Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C. {ECO:0000269|PubMed:20615244}.
uniprot
proteins
mass_dalton
88054
uniprot
proteins
protein_family
Integrin beta chain family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15156152
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15611078
uniprot
proteins
pubmed
20615244
uniprot
proteins
pubmed
2211615
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
2328726
uniprot
proteins
pubmed
2371275
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
35687021
uniprot
proteins
sequence_length
799
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 720..742; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins