Q9R0A3
uniprot
Q9R0A3
canonical
amino_acid_sequence
MAVHYNKILSAKAAVDCSIPVSVNASIKYADQQRREKLRKELARCEKEFKLSKSAMQTNSKMNSKFFVNSLQRPSGEPQDQDVLIEERLTRYPSFSKSLIPSPEGLHLSLPESNKILMNGTQKYPSTAPPRYSGCGHGYDRRPRSAHQFQVVISKTPSGDLLEKHADLFSNNQSPFTPRTLKTEAKSFLSQYRYYTPAKRRRDFSDQRMEAETQTELSSFNSELGTAEKKSSKDSDVSIKQAPNYMRNGAEDKIAPLSLQGQNLAWDKSKDGILQPSSERAPCTQFSPDSKIYSDEEELLYLSFMENVTDEILKLGLFSNRFLERLFERHIRKNKHHLEEGKMRYLLHGLKVDLGCISEEEQNSFRIFNEFHFQKALTSRENRFINDTEAVNHHERQQYQEALNMLSSVPKDENKMFSFPGEFLLPAHKVKHSEGVIVQQVNDETDFEALPWDGNNPSVSDSFIDQETSVDVIEGDSDFEMVETSRELCCLSTSLSPSVPLPSIEGGSNHDKELSTLKIMEMSIED
uniprot
proteins
function
FUNCTION: Involved in the maintenance of both rod and cone photoreceptor cells (By similarity). Required for photoreceptor-specific localization of proximal connecting cilium (CC) proteins RPGR, AHI1, NPHP1, NPHP4, and RPGRIP1 at the distal CC, a photoreceptor-specific extension of the primary cilium transition zone (By similarity). Maintenance of protein localization at the photoreceptor-specific distal CC is essential for normal microtubule stability and to prevent photoreceptor degeneration (By similarity). {ECO:0000250|UniProtKB:Q80VP2}.
uniprot
proteins
mass_dalton
59983
uniprot
proteins
pubmed
12736779
uniprot
proteins
sequence_length
526
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9P0W8}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9P0W8}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9P0W8}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q80VP2}. Note=Localizes to the microtubule network. {ECO:0000250|UniProtKB:Q9P0W8}.
uniprot
proteins