Ctbs
entrez
81652
canonical
uniprot
Q01460
canonical
ensembl
ENSRNOG00000015573
resolver
ensembl
ENSRNOG00055023400
resolver
ensembl
ENSRNOG00060000862
resolver
ensembl
ENSRNOG00065012824
resolver
ensp
ENSRNOP00000020972
resolver
ensp
ENSRNOP00055032656
resolver
ensp
ENSRNOP00060000375
resolver
ensp
ENSRNOP00065016158
resolver
enst
ENSRNOT00000020972
resolver
enst
ENSRNOT00055040216
resolver
enst
ENSRNOT00060001070
resolver
enst
ENSRNOT00065020953
resolver
genesymbol
Ctbs
resolver
genesymbol_syn
Ctb
resolver
uniprot_entry
DIAC_RAT
resolver
amino_acid_sequence
MALSDLLELTLLLLLPLLERLSAEDCPCSEASLCRPIRHHRDFEVFVFDVGQKTWKSYDWSQITTVAVFGKYDSELMCYAHSKGARVVLKGDVALKDIINPTFRASWIAQKVALAKAQHMDGINIDIEQEVDCSSPEYEALTALVRETTEGFHREIEGSQVTFDVAWSPKGIDKRCYNYTGIADACDFLFVMSYDEQSQIWSECIAAANAPYNQTLTGYGDYLRMGISPRKLVMGIPWYGYDYICLNLSKDDVCAIAKVPFRGAPCSDAAGHQVPYRVIMKQVNSSVSGSQWNQDQQAPYYNYKDPTGRLHQVWYDNPRSISLKAAFVKHYGLRGIGMWNANCLDYSDDALAREQTEEMWGALRPRL
uniprot
proteins
ec_number
3.2.1.-
uniprot
proteins
function
FUNCTION: Reducing-end exoglycosidase involved in glycan degradation. Hydrolyzes N,N'-diacetylchitobiose (GlnNAc2) and higher chitin-oligosaccharides (GlcNAc(n)) to monomeric GlcNAc acting on reducing-end residues (PubMed:2751306). During N-linked glycoprotein degradation, it cleaves single GlcNAc molecules uniquely from the reducing end of N,N'-diacetylchitobiose units linking oligosaccharides to proteins, and therefore it functions after cleavage of the Asn-GlcNAc bond and asparagine removal by glycosylasparaginase (PubMed:2751306). {ECO:0000269|PubMed:2751306}.
uniprot
proteins
mass_dalton
41531
uniprot
proteins
pathway_participation
PATHWAY: Glycan metabolism; N-glycan degradation. {ECO:0000269|PubMed:2751306}.; PATHWAY: Glycan degradation; chitin degradation. {ECO:0000269|PubMed:2751306}.
uniprot
proteins
protein_family
Glycosyl hydrolase 18 family
uniprot
proteins
pubmed
1527079
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2751306
uniprot
proteins
sequence_length
367
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000305|PubMed:2751306}.
uniprot
proteins