Tmem182
entrez
381339
canonical
uniprot
B2RVY9
canonical
ensembl
ENSMUSG00000079588
resolver
ensp
ENSMUSP00000110413
resolver
enst
ENSMUST00000114765
resolver
genesymbol
Tmem182
resolver
uniprot_entry
TM182_MOUSE
resolver
amino_acid_sequence
MRLNVAVFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEQNIENITFHHEGFFWRCWFSGVVEENNSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAIIYRGFWAVLLLLGVVAALTASFLIICAAPFSSHFLYKAGGGSYIASGVLFSLVVILYVIWVQAVADMESYRALRMRDCWEFTPSILYGWSFFLAPAGVFFSLLAGLLFLVVGRHIQIHH
uniprot
proteins
function
FUNCTION: Negatively regulates myogenesis and skeletal muscle regeneration via its association with ITGB1 (PubMed:34427057). Modulates ITGB1 activation by decreasing ITGB1-LAMB1 interaction and inhibiting ITGB1-mediated intracellular signaling during myogenesis (PubMed:34427057). {ECO:0000269|PubMed:34427057}.
uniprot
proteins
mass_dalton
25845
uniprot
proteins
protein_family
TMEM182 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18803820
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
34427057
uniprot
proteins
sequence_length
229
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:A0A1D5NY17}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 115..135; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 154..174; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins