TIMM13
entrez
26517
canonical
uniprot
Q9Y5L4
canonical
ensembl
ENSG00000099800
resolver
ensp
ENSP00000215570
resolver
enst
ENST00000215570
resolver
genesymbol
TIMM13
resolver
genesymbol_syn
TIM13B
resolver
genesymbol_syn
TIMM13A
resolver
genesymbol_syn
TIMM13B
resolver
hgnc
HGNC:11816
resolver
uniprot
P62206
resolver
uniprot
Q9UHL8
resolver
uniprot
Q9WTL1
resolver
uniprot_entry
TIM13_HUMAN
resolver
uniprot_sec
P62206
resolver
uniprot_sec
Q9UHL8
resolver
uniprot_sec
Q9WTL1
resolver
amino_acid_sequence
MEGGFGSDFGGSGSGKLDPGLIMEQVKVQIAVANAQELLQRMTDKCFRKCIGKPGGSLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERANM
uniprot
proteins
function
FUNCTION: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. {ECO:0000269|PubMed:11489896, ECO:0000269|PubMed:15254020}.
uniprot
proteins
mass_dalton
10500
uniprot
proteins
protein_family
Small Tim family
uniprot
proteins
pubmed
10552927
uniprot
proteins
pubmed
10611480
uniprot
proteins
pubmed
11489896
uniprot
proteins
pubmed
15254020
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
95
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:11489896}; Peripheral membrane protein {ECO:0000269|PubMed:11489896}; Intermembrane side {ECO:0000269|PubMed:11489896}.
uniprot
proteins