288001
entrez
288001
canonical
uniprot
P08932
canonical
ensembl
ENSRNOG00000030387
resolver
ensembl
ENSRNOG00055004732
resolver
ensp
ENSRNOP00000073812
resolver
ensp
ENSRNOP00055005660
resolver
enst
ENSRNOT00000084867
resolver
enst
ENSRNOT00055007538
resolver
uniprot
Q5M894
resolver
uniprot_entry
KNT2_RAT
resolver
uniprot_sec
Q5M894
resolver
amino_acid_sequence
MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP
uniprot
proteins
function
FUNCTION: Kininogens are plasma glycoproteins with a number of functions: (1) as precursor of the active peptide bradykinin they effect smooth muscle contraction, induction of hypotension and increase of vascular permeability. (2) They play a role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII. (3) They are inhibitor of thiol proteases.
uniprot
proteins
mass_dalton
47704
uniprot
proteins
post_translational_modification
PTM: As T-kinin is preceded by a Met instead of an Arg or Lys, it is not released from its precursor by either tissue or plasma kallikrein.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2413018
uniprot
proteins
pubmed
2413019
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space.
uniprot
proteins