Baiap2
entrez
108100
canonical
uniprot
Q8BKX1
canonical
ensembl
ENSMUSG00000025372
resolver
ensp
ENSMUSP00000026436
resolver
ensp
ENSMUSP00000074674
resolver
ensp
ENSMUSP00000099310
resolver
ensp
ENSMUSP00000101840
resolver
ensp
ENSMUSP00000233544
resolver
ensp
ENSMUSP00000233548
resolver
ensp
ENSMUSP00000233549
resolver
ensp
ENSMUSP00000233554
resolver
enst
ENSMUST00000106233
resolver
genesymbol
Baiap2
resolver
uniprot
B1AZ46
resolver
uniprot
Q3UKP6
resolver
uniprot
Q91V97
resolver
uniprot
Q923V9
resolver
uniprot
Q923W0
resolver
uniprot_entry
B1AZ46_MOUSE
resolver
uniprot_entry
BAIP2_MOUSE
resolver
uniprot_entry
Q3UKP6_MOUSE
resolver
uniprot_sec
Q91V97
resolver
uniprot_sec
Q923V9
resolver
uniprot_sec
Q923W0
resolver
amino_acid_sequence
MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTFAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEETLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLMQQMANSNGSILPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQENVPVMNGVAGPDSEDYNPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLALPPPDYGTSSRAFPTQTAGTFKQRPYSVAVPAFSQGLDDYGARSVSRNPFANVHLKPTVTNDRSAPLLS
uniprot
proteins
function
FUNCTION: Adapter protein that links membrane-bound small G proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth, neuronal differentiation and neuronal migration (PubMed:38149472). Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions. {ECO:0000269|PubMed:17115031, ECO:0000269|PubMed:38149472}.
uniprot
proteins
mass_dalton
59237
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues by INSR in response to insulin treatment. {ECO:0000250}.
uniprot
proteins
pubmed
10814512
uniprot
proteins
pubmed
11514062
uniprot
proteins
pubmed
12006592
uniprot
proteins
pubmed
12884081
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17115031
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
38149472
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UQB8}. Cell projection, filopodium {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles. Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites (By similarity). {ECO:0000250}.
uniprot
proteins