Ferry3
entrez
28040
canonical
uniprot
Q91YN0
canonical
ensembl
ENSMUSG00000030347
resolver
ensp
ENSMUSP00000032497
resolver
ensp
ENSMUSP00000236412
resolver
enst
ENSMUST00000032497
resolver
genesymbol
Ferry3
resolver
genesymbol_syn
D6Wsu163e
resolver
uniprot
Q3UVK4
resolver
uniprot_entry
FERY3_MOUSE
resolver
uniprot_sec
Q3UVK4
resolver
amino_acid_sequence
MKKNRERFCNKEREFVYKFQVGRERLELRVPLRFPVEENASHLHGRLMLLHSLPCFIESDLKDALSRFIEEESLRDHDSDAEACLEAVKSGEVDLHQLASAWAKAYAETTLEHARPEEPDWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELIGERDVELKKLRERQGIEMEKVMQELGKSLTDQDVNSLAAQHFESQQDLENKWSNELKQSTAIQKQEYQEWVIKLHQDLKNPNNSSLSEEIKVQPSQFRESADAAGRIYEEQRKLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRTHGSGVKLHRLQTALSLYSTSLCGLVLLVDNRINSYSGIKRDFATVCQECTDFHFPRIEEQLEVVQQVALYARTQRKSKCKEARDSGNQNGGSDDKSKNAERNYLNILPGEFYITRHSNLSEIHVAFHLCVDDNVKSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLRRAELVFKCVKGFMMEMASWDGGISRTVQFLVPQSISEEMFYQLSNMLPQIFRVSSTLTLTSKH
uniprot
proteins
function
FUNCTION: Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (By similarity). Plays a role in mast cell degranulation (By similarity). {ECO:0000250|UniProtKB:D4A770, ECO:0000250|UniProtKB:Q9NQ89}.
uniprot
proteins
mass_dalton
63644
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
552
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:D4A770}. Early endosome {ECO:0000250|UniProtKB:Q9NQ89}.
uniprot
proteins