FANK1
entrez
92565
canonical
uniprot
Q8TC84
canonical
ensembl
ENSG00000203780
resolver
ensp
ENSP00000357680
resolver
ensp
ENSP00000357682
resolver
genesymbol
FANK1
resolver
hgnc
HGNC:23527
resolver
uniprot
Q6UXY9
resolver
uniprot
Q6X7T6
resolver
uniprot_entry
FANK1_HUMAN
resolver
uniprot_sec
Q6UXY9
resolver
uniprot_sec
Q6X7T6
resolver
amino_acid_sequence
MEPQKIMPPSKPHPPVVGKVTHHSIELYWDLEKKAKRQGPQEQWFRFSIEEEDPKMHTYGIIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTREPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLLEERKKKQRPKKSCVC
uniprot
proteins
function
FUNCTION: Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis. {ECO:0000269|PubMed:20978819, ECO:0000269|PubMed:27060496}.
uniprot
proteins
mass_dalton
38341
uniprot
proteins
post_translational_modification
PTM: Polyubiquitinated. Polyubiquitination leads to proteasomal degradation. {ECO:0000269|PubMed:27060496}.
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17604233
uniprot
proteins
pubmed
20978819
uniprot
proteins
pubmed
27060496
uniprot
proteins
sequence_length
345
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20978819, ECO:0000269|PubMed:27060496}. Cytoplasm, cytosol {ECO:0000269|PubMed:20978819}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9DAM9}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9DAM9}.
uniprot
proteins