PFN2
entrez
5217
canonical
uniprot
P35080
canonical
ensembl
ENSG00000070087
resolver
ensp
ENSP00000239940
resolver
ensp
ENSP00000410464
resolver
genesymbol
PFN2
resolver
hgnc
HGNC:8882
resolver
uniprot
B2R4C8
resolver
uniprot
D3DNI4
resolver
uniprot
Q4VBQ4
resolver
uniprot
Q8WVF9
resolver
uniprot
Q9HBK2
resolver
uniprot_entry
PROF2_HUMAN
resolver
uniprot_sec
B2R4C8
resolver
uniprot_sec
D3DNI4
resolver
uniprot_sec
Q4VBQ4
resolver
uniprot_sec
Q8WVF9
resolver
uniprot_sec
Q9HBK2
resolver
amino_acid_sequence
MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
uniprot
proteins
function
FUNCTION: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
uniprot
proteins
mass_dalton
15046
uniprot
proteins
protein_family
Profilin family
uniprot
proteins
pubmed
10600384
uniprot
proteins
pubmed
11027290
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
36173861
uniprot
proteins
pubmed
7758455
uniprot
proteins
pubmed
8365484
uniprot
proteins
sequence_length
140
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
uniprot
proteins