BCL2L2
entrez
599
canonical
uniprot
Q92843
canonical
ensembl
ENSG00000129473
resolver
ensembl
ENSG00000258643
resolver
ensp
ENSP00000250405
resolver
ensp
ENSP00000504570
resolver
genesymbol
BCL2L2
resolver
genesymbol_syn
BCLW
resolver
genesymbol_syn
KIAA0271
resolver
hgnc
HGNC:42959
resolver
hgnc
HGNC:995
resolver
uniprot
A8K0F4
resolver
uniprot
Q2M3U0
resolver
uniprot
Q5U0H4
resolver
uniprot_entry
B2CL2_HUMAN
resolver
uniprot_sec
A8K0F4
resolver
uniprot_sec
Q2M3U0
resolver
uniprot_sec
Q5U0H4
resolver
amino_acid_sequence
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
uniprot
proteins
function
FUNCTION: Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. {ECO:0000269|PubMed:8761287}.
uniprot
proteins
mass_dalton
20746
uniprot
proteins
protein_family
Bcl-2 family
uniprot
proteins
pubmed
11423909
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
12651847
uniprot
proteins
pubmed
12660157
uniprot
proteins
pubmed
12952938
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8761287
uniprot
proteins
pubmed
9039502
uniprot
proteins
sequence_length
193
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000269|PubMed:11423909, ECO:0000269|PubMed:12952938}; Peripheral membrane protein {ECO:0000269|PubMed:11423909, ECO:0000269|PubMed:12952938}. Note=Loosely associated with the mitochondrial membrane in healthy cells. During apoptosis, tightly bound to the membrane.
uniprot
proteins