Ccl11
entrez
20292
canonical
uniprot
P48298
canonical
ensembl
ENSMUSG00000020676
resolver
ensp
ENSMUSP00000000342
resolver
enst
ENSMUST00000000342
resolver
genesymbol
Ccl11
resolver
genesymbol_syn
Scya11
resolver
uniprot_entry
CCL11_MOUSE
resolver
amino_acid_sequence
MQSSTALLFLLLTVTSFTSQVLAHPGSIPTSCCFIMTSKKIPNTLLKSYKRITNNRCTLKAIVFKTRLGKEICADPKKKWVQDATKHLDQKLQTPKP
uniprot
proteins
function
FUNCTION: Chemokine that plays a central role in both allergic and non-allergic inflammatory reactions by inducing the migration of different leukocyte types including eosinophils, basophils, macrophages and dendritic cells (PubMed:7568052, PubMed:8574847). Exerts its effects primarily by binding to the CCR3 receptor. Induces also chemotaxis of endothelial cells and promotes angiogenesis by activating the PI3K/Akt pathway. {ECO:0000250|UniProtKB:P51671, ECO:0000269|PubMed:7568052, ECO:0000269|PubMed:8574847}.
uniprot
proteins
mass_dalton
10893
uniprot
proteins
post_translational_modification
PTM: O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues. {ECO:0000250|UniProtKB:P51671}.
uniprot
proteins
protein_family
Intercrine beta (chemokine CC) family
uniprot
proteins
pubmed
10438970
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15647285
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
7568052
uniprot
proteins
pubmed
8574847
uniprot
proteins
pubmed
9169149
uniprot
proteins
sequence_length
97
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P51671, ECO:0000305|PubMed:7568052}.
uniprot
proteins