P16036
uniprot
P16036
canonical
amino_acid_sequence
MFSSVAHLARANPFNAPHLQLVHDVSGPRSPPGPPRRSRHLAAAAVEGYSCEFGSMKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVFKALYSNILGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLREAVPKMYKEEGLNAFYKGVAPVWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSTASQVLQRLGFRGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTE
uniprot
proteins
function
FUNCTION: Inorganic ion transporter that transports phosphate or copper ions across the mitochondrial inner membrane into the matrix compartment (By similarity). Mediates proton-coupled symport of phosphate ions necessary for mitochondrial oxidative phosphorylation of ADP to ATP (By similarity). Transports copper ions probably in the form of anionic copper(I) complexes to maintain mitochondrial matrix copper pool and to supply copper for cytochrome C oxidase complex assembly (By similarity). May also play a role in regulation of the mitochondrial permeability transition pore (mPTP) (PubMed:18667415). {ECO:0000250|UniProtKB:P12234, ECO:0000250|UniProtKB:Q00325, ECO:0000269|PubMed:18667415}.
uniprot
proteins
mass_dalton
39445
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
18667415
uniprot
proteins
pubmed
1985946
uniprot
proteins
pubmed
2250020
uniprot
proteins
pubmed
2670944
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:2250020}; Multi-pass membrane protein {ECO:0000269|PubMed:2250020}.
uniprot
proteins
transmembrane_region
TRANSMEM 58..80; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 116..135; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 156..177; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 213..232; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 256..278; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 309..327; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins