Pomgnt2
entrez
215494
canonical
uniprot
Q8BW41
canonical
ensembl
ENSMUSG00000066235
resolver
ensp
ENSMUSP00000095868
resolver
ensp
ENSMUSP00000149077
resolver
ensp
ENSMUSP00000149753
resolver
ensp
ENSMUSP00000186487
resolver
ensp
ENSMUSP00000186488
resolver
ensp
ENSMUSP00000186497
resolver
enst
ENSMUST00000084743
resolver
enst
ENSMUST00000216669
resolver
enst
ENSMUST00000217610
resolver
genesymbol
Pomgnt2
resolver
genesymbol_syn
Ago61
resolver
genesymbol_syn
Eogtl
resolver
genesymbol_syn
Gtdc2
resolver
uniprot
Q58F17
resolver
uniprot
Q8BXZ9
resolver
uniprot
Q8K0M5
resolver
uniprot_entry
PMGT2_MOUSE
resolver
uniprot_sec
Q58F17
resolver
uniprot_sec
Q8BXZ9
resolver
uniprot_sec
Q8K0M5
resolver
amino_acid_sequence
MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALGQQSLDPVLGLKIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNSSVMLPNLGSRRFQPALLDLSTVEDHNAQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAQEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLNVSHAGAPLGEEYILVFSRTQNRLILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVAWRNMIRENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTRVDIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNRSLLGPFADVLVCST
uniprot
proteins
ec_number
2.4.1.312
uniprot
proteins
function
FUNCTION: O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein (By similarity). Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:24256719). {ECO:0000250|UniProtKB:Q8NAT1, ECO:0000269|PubMed:24256719}.
uniprot
proteins
mass_dalton
66661
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000269|PubMed:24256719}.
uniprot
proteins
protein_family
Glycosyltransferase 61 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22958903
uniprot
proteins
pubmed
24256719
uniprot
proteins
sequence_length
580
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8NAT1}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8NAT1}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..25; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins