ATP6V0D2
entrez
245972
canonical
uniprot
Q8N8Y2
canonical
ensembl
ENSG00000147614
resolver
ensp
ENSP00000285393
resolver
enst
ENST00000285393
resolver
genesymbol
ATP6V0D2
resolver
hgnc
HGNC:18266
resolver
uniprot_entry
VA0D2_HUMAN
resolver
amino_acid_sequence
MLEGAELYFNVDHGYLEGLVRGCKASLLTQQDYINLVQCETLEDLKIHLQTTDYGNFLANHTNPLTVSKIDTEMRKRLCGEFEYFRNHSLEPLSTFLTYMTCSYMIDNVILLMNGALQKKSVKEILGKCHPLGRFTEMEAVNIAETPSDLFNAILIETPLAPFFQDCMSENALDELNIELLRNKLYKSYLEAFYKFCKNHGDVTAEVMCPILEFEADRRAFIITLNSFGTELSKEDRETLYPTFGKLYPEGLRLLAQAEDFDQMKNVADHYGVYKPLFEAVGGSGGKTLEDVFYEREVQMNVLAFNRQFHYGVFYAYVKLKEQEIRNIVWIAECISQRHRTKINSYIPIL
uniprot
proteins
function
FUNCTION: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). May play a role in coupling of proton transport and ATP hydrolysis (By similarity). Regulator of osteoclast fusion and bone formation (By similarity). {ECO:0000250|UniProtKB:P61421, ECO:0000250|UniProtKB:Q80SY3}.
uniprot
proteins
mass_dalton
40426
uniprot
proteins
protein_family
V-ATPase V0D/AC39 subunit family
uniprot
proteins
pubmed
12384298
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
350
uniprot
proteins