POU2F3
entrez
25833
canonical
uniprot
Q9UKI9
canonical
ensembl
ENSG00000137709
resolver
ensp
ENSP00000260264
resolver
ensp
ENSP00000441687
resolver
genesymbol
POU2F3
resolver
genesymbol_syn
OTF11
resolver
genesymbol_syn
PLA1
resolver
hgnc
HGNC:19864
resolver
uniprot
A8K7H8
resolver
uniprot
B4DY07
resolver
uniprot
F5GWW6
resolver
uniprot
Q3MIY3
resolver
uniprot
Q9UKR7
resolver
uniprot
Q9Y504
resolver
uniprot_entry
PO2F3_HUMAN
resolver
uniprot_sec
A8K7H8
resolver
uniprot_sec
B4DY07
resolver
uniprot_sec
F5GWW6
resolver
uniprot_sec
Q3MIY3
resolver
uniprot_sec
Q9UKR7
resolver
uniprot_sec
Q9Y504
resolver
amino_acid_sequence
MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTYLH
uniprot
proteins
function
FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation (PubMed:11329378). The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues (PubMed:35576971). {ECO:0000269|PubMed:11329378, ECO:0000269|PubMed:35576971}.
uniprot
proteins
mass_dalton
47432
uniprot
proteins
protein_family
Class-2 subfamily
uniprot
proteins
protein_family
POU transcription factor family
uniprot
proteins
pubmed
10473598
uniprot
proteins
pubmed
11329378
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
35576971
uniprot
proteins
pubmed
36197978
uniprot
proteins
sequence_length
436
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P31362}.
uniprot
proteins