Rsc1a1
entrez
69994
canonical
uniprot
Q9ER99
canonical
genesymbol
Rsc1a1
resolver
uniprot
B1AUM1
resolver
uniprot
B2RWX9
resolver
uniprot
Q78HA0
resolver
uniprot
Q9CVU8
resolver
uniprot_entry
RSCA1_MOUSE
resolver
uniprot_sec
B1AUM1
resolver
uniprot_sec
B2RWX9
resolver
uniprot_sec
Q78HA0
resolver
uniprot_sec
Q9CVU8
resolver
amino_acid_sequence
MSSLPTSDGFDHPAPSGQSPEVGSPTSLARSVSASVCAIKPGDPNSIESLAMEATKASAEFQTNSKKTDPPPLQVLPDLASSAEQSLAMPFHKSSKEAVVAGNLEKSVEKGTQGLRVYLHTRQDASLTLTTTGMREPQIFAEEKSWHPENQTPSPVNGLQQHRETGSVQREAGQQSVPQDQGCLCDAEDLELHEEVVSLEALRKGELQRHAHLPSAEKGLPASGLCSCPCSEALMEVDTAEQSLVAMCSSTGRQDAVIKSPSVAHLASDNPTMEVETLQSNPSCEPVEHSILTRELQLPEDNVDMSTMDNKDDNSSSLLSGHGQPSVESAEEFCSSVTVALKELHELLVISCKPASEESPEHVTCQSEIGAESQPSVSDLSGRRVQSVHLTPSDQYSQGSCHQATSESGKTEIVGTAPCAAVEDEASTSFEGLGDGLSPDREDVRRSTESARKSCSVAITSAKLSEQLPCTSGVEIAPELAASEGAHSQPSEHVHNPGPDRPETSSVCPGAGLPRSGLDQPPTQSLSTPSVLPPFIFPAADVDRILGAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT
uniprot
proteins
function
FUNCTION: Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network (By similarity). Regulates the expression of SLC5A1 in a tissue-specific manner and is specifically involved in its regulation in the small intestine. {ECO:0000250, ECO:0000269|PubMed:15601832}.
uniprot
proteins
mass_dalton
61251
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15601832
uniprot
proteins
pubmed
16024787
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
582
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15601832}. Nucleus {ECO:0000269|PubMed:15601832}. Golgi apparatus, trans-Golgi network {ECO:0000250}. Note=Localizes at the inner side of the plasma membrane.
uniprot
proteins