TTYH1
entrez
57348
canonical
uniprot
Q9H313
canonical
ensembl
ENSG00000167614
resolver
ensembl
ENSG00000275650
resolver
ensembl
ENSG00000276537
resolver
ensembl
ENSG00000276887
resolver
ensp
ENSP00000301194
resolver
ensp
ENSP00000365713
resolver
ensp
ENSP00000365714
resolver
genesymbol
TTYH1
resolver
hgnc
HGNC:13476
resolver
uniprot
B0VJY3
resolver
uniprot
B0VJY4
resolver
uniprot
B0VJY5
resolver
uniprot
B2VAL9
resolver
uniprot
Q5U682
resolver
uniprot
Q68A17
resolver
uniprot
Q6L750
resolver
uniprot
Q6ZTE5
resolver
uniprot
Q8WUU2
resolver
uniprot_entry
TTYH1_HUMAN
resolver
uniprot_sec
B0VJY3
resolver
uniprot_sec
B0VJY4
resolver
uniprot_sec
B0VJY5
resolver
uniprot_sec
B2VAL9
resolver
uniprot_sec
Q5U682
resolver
uniprot_sec
Q68A17
resolver
uniprot_sec
Q6L750
resolver
uniprot_sec
Q6ZTE5
resolver
uniprot_sec
Q8WUU2
resolver
amino_acid_sequence
MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI
uniprot
proteins
function
FUNCTION: Calcium-independent, swelling-dependent volume-regulated anion channel (VRAC-swell) which plays a pivotal role in the process of regulatory volume decrease (RVD) in the brain through the efflux of anions like chloride and organic osmolytes like glutamate. {ECO:0000250|UniProtKB:Q9D3A9}.; FUNCTION: [Isoform 3]: Ca(2+)-independent, swelling-activated chloride channel, possibly involved in regulation of cell volume. {ECO:0000269|PubMed:15010458}.
uniprot
proteins
mass_dalton
49051
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. Contains high-mannose, hybrid and complex oligosaccharides. {ECO:0000269|PubMed:18260827}.
uniprot
proteins
protein_family
Tweety family
uniprot
proteins
pubmed
10950931
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15010458
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17116230
uniprot
proteins
pubmed
18260827
uniprot
proteins
pubmed
34385445
uniprot
proteins
sequence_length
450
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:34385445}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 44..64; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 89..109; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 215..235; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 241..261; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 391..411; /note="Helical; Name=5"; /evidence="ECO:0000255
uniprot
proteins