P29391
uniprot
P29391
canonical
amino_acid_sequence
MTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREGAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSARTDPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFERLTLKHD
uniprot
proteins
function
FUNCTION: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Degraded to release iron upon autophagy activation by nutrient starvation (PubMed:25327288). {ECO:0000269|PubMed:19154717, ECO:0000269|PubMed:25327288}.
uniprot
proteins
mass_dalton
20802
uniprot
proteins
protein_family
Ferritin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19154717
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25327288
uniprot
proteins
pubmed
2708374
uniprot
proteins
pubmed
7648356
uniprot
proteins
sequence_length
183
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:25327288}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:25327288}. Autolysosome {ECO:0000269|PubMed:25327288}.
uniprot
proteins