Nfkbid
entrez
243910
canonical
uniprot
Q2TB02
canonical
ensembl
ENSMUSG00000036931
resolver
ensp
ENSMUSP00000042317
resolver
ensp
ENSMUSP00000103810
resolver
ensp
ENSMUSP00000103811
resolver
enst
ENSMUST00000046177
resolver
enst
ENSMUST00000108175
resolver
enst
ENSMUST00000108176
resolver
genesymbol
Nfkbid
resolver
genesymbol_syn
Ikbns
resolver
uniprot
A0A217FL61
resolver
uniprot
Q3TJP0
resolver
uniprot
Q8CIW1
resolver
uniprot_entry
A0A217FL61_MOUSE
resolver
uniprot_entry
IKBD_MOUSE
resolver
uniprot_sec
Q3TJP0
resolver
uniprot_sec
Q8CIW1
resolver
amino_acid_sequence
MEDSLDTRLYPEPSLSQVGSWRVSSLPSGSPQLPSPTGPSLETARAHILALGPQQLLAQDEEGDTLLHLFAARGLRWAAYAAAEVLQMYRQLDIREHKGKTPLLVAAAANQPLIVEDLLSLGAEPNATDHQGRSVLHVAATYGLPGVLSAVFKSGIQVDLEARDFEGLTPLHTAVLALNAAMLPASVCPRMQNSQARDRLTCVQMLLQMGASHTSQEIKSNKTILHLAVQAANPTLVQLLLGLPRGDLRAFVNMKAHGNTALHMAAALPPGPPQEAIVRHLLAAGADPTLRNLENEQPVHLLRPGPGPEGLRQLLKRSRTAPPGLSS
uniprot
proteins
function
FUNCTION: Regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses (PubMed:11931770, PubMed:15749903, PubMed:16410444, PubMed:16413922, PubMed:17641034). Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR) (PubMed:25282160). According to PubMed:11931770, it may also regulate TCR-induced negative selection of thymocytes (PubMed:11931770). {ECO:0000269|PubMed:11931770, ECO:0000269|PubMed:15749903, ECO:0000269|PubMed:16410444, ECO:0000269|PubMed:16413922, ECO:0000269|PubMed:17641034, ECO:0000269|PubMed:25282160}.
uniprot
proteins
mass_dalton
34942
uniprot
proteins
protein_family
NF-kappa-B inhibitor family
uniprot
proteins
pubmed
11931770
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15749903
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16410444
uniprot
proteins
pubmed
16413922
uniprot
proteins
pubmed
17641034
uniprot
proteins
pubmed
25282160
uniprot
proteins
sequence_length
327
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11931770}.
uniprot
proteins