Gon4l
entrez
499653
canonical
uniprot
Q535K8
canonical
ensembl
ENSRNOG00000020297
resolver
ensembl
ENSRNOG00065024529
resolver
ensp
ENSRNOP00000069180
resolver
ensp
ENSRNOP00000071608
resolver
ensp
ENSRNOP00000100475
resolver
ensp
ENSRNOP00000110922
resolver
enst
ENSRNOT00000078913
resolver
enst
ENSRNOT00000148192
resolver
enst
ENSRNOT00000160007
resolver
genesymbol
Gon4l
resolver
genesymbol_syn
Gon4
resolver
uniprot
A0A0G2K0W6
resolver
uniprot
A0ABK0LB26
resolver
uniprot
A0ABK0M5Z7
resolver
uniprot
Q535K7
resolver
uniprot_entry
A0A0G2K0W6_RAT
resolver
uniprot_entry
A0ABK0LB26_RAT
resolver
uniprot_entry
A0ABK0M5Z7_RAT
resolver
uniprot_entry
GON4L_RAT
resolver
uniprot_sec
Q535K7
resolver
amino_acid_sequence
MLPCKKRSGVTESAQQQDDQEGEDLHLEAAVKPDTDQLPDCTSESLSWGQSHDSAGCPEVHSMQDVGSQLSVEGTPLSSKMLTQRVNLAVSEAVDVPVSQEIPVPSLESSHSLPVHMGKGRLQSTASRKGKKIAFMPGQVTREDGGDHTVPEEPPSGEHAEEVKAEGGELEMHSEGDLPSLSSGSQSAKPRAQPRKSFQPDGSAFPQEKSLGPLVRQAEEDMEDGGLFIPTEEQDGEESDKRKKTKKGTKRKRDGRGQEQGTMTYDPKVDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPLFEPKMTRSKLKEVVEKGVVIPTWNISPIKKASETKQPPQFVDIHLEDDDSSDEEYQPDEEEEDETAEESLLESDVESAASSPRGVKRSRLRLSSEAAEADEESGVLSEVEKVATPALRHISAEVVPMGPPPPPKPKQTRDSTFMEKLNAVDEELAASPVCMDSFQPMEDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKLWLGGLLNDDVENEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNGLMEELFETVQSVVPSKFQDEMGFSNMEDDGPEEEERVTESRPSFNTPQALRFEEPLANLLNERHRTVKELLEQLKMKKSSVRQQPEVEKLKPQTEKVHQTLVLDPAQRSRLQQQMQQHVQLLTQIYLLTTSNPNLSSEASTTRVFLKELGTFAENSTALHQQFNPRFQTLFQPCNWVGAMQLIEDFTHISIDCSPHKTVKKTASEFPCLPKQVAWILATNKVFMYPELLPICSLKANNPRDKTIFTKAEDNLLALGLKHFEGTEFPKPLISKYLVTCKTAHQLTVRIKNLNLNRAPNNVIKFYKKTKQLPVLVRCCEEIQPHQWKPPIEKEEHRLPFWLKASLQSIQEELRNLAGGATAGGSVTAATETSTDQHLQKTSPVVGGDTQYPLLLPKGVVLKLKPGSKRFSRKAWRQKRPLVQKPLLIQPSPSVQPVFNPGKMATWPTQSEVPPSNTVVQIPHLIQPAAVLQTLPGFPSVGVCGEDSFESPAALPAMPSGSEARTSFPWSESQSAPPSSSAPKLMLPSLGPSKFRKPYVRRKPTRRKGAKASPCVKPAPIIHPTPVIFTVPATTVKVVSLGGGCNMIQPVTAAVAPSPQTIPITTLLVNPTSFPCSLNQPLVASSISPLLVSSNPLALPVTSLPEEKAHVSLDIAEGKNAPQNPEPKIKPQEPTPQCATVFSKEEPRSWHPSADTGNQEAVSESSACSWAAVKTEGQEGSSEKSVCGWTVVKTEDGGHAVQPLPQDPQDSLNSPSKDLLNMVKLEAEDCMEEISSDFPKQDIGEEVKEECCMELDRDSPQEKASSVSEMSKQTATPREETQAAKSPTVSQDAPDAIRDASKGLPQSTLSSMDQGTVLNSPPGKPEDSANADGQSVGTPAGTDTGAEKDGAEEEEEEDFDDLTQDEEDELSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMETLQKEDEATDEAGGGAAEKPPSTLASPHTAPEVETSITPAGESIKAAGKGRSSHRARSRRGSRARASKDASKLLLLYDEDILDRDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQIIYEFESNAQMHSAVDLFKSLQTLLHDWPQLLKDFAAFLLPEQALSCGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQDITELKTQMWQLLRGHDHLQDEFSIFFDHLRPAANRMGDFEEINWTEEKEYEFDGFEEVILPEVEEEEEPAKVSTASKSKRRKEIGVQHQDKESEWPEAAKDGSCPCHEGGPESKLKKSKRRNCHCSSKVCDSKSYKSKEPLELVGSGPLQEASTVPGTKEAGQGKDMSEEETMEGQENVEVSQNKTGRTTRKGEAPIPGSTVRTALLCSAEVTPIELSLEGPTCCSPETPRLPPQTGAVVCSVRRNQAGPEVVSCLGTSSIPPKEGEDQKAVANSETIAPLPETSETERLPGTVELPAPLPSPVSLSTRDTGRRHIYGKAGTQSWLLDNRAEAKAAHMVAPIRGTSSGASASEAAPTASREGLAEDSETQGKGPEAVLPKASEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPHTFSVISQQLGNKTPVEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE
uniprot
proteins
function
FUNCTION: Acts as a key transcription regulator of histones. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with GON4L and MIZF. Together with CRAMP1, binds to the promoters of H1 genes (H1-2, H1-3, H1-4, H1-5 and H1-10/H1x), driving their transcription (By similarity). Also acts as a transcription corepressor, as part of a complex with YY1, SIN3A and HDAC1. Required for B-cell lymphopoiesis (By similarity). {ECO:0000250|UniProtKB:Q3T8J9, ECO:0000250|UniProtKB:Q9DB00}.
uniprot
proteins
mass_dalton
247903
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
2256
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00810}. Chromosome {ECO:0000250|UniProtKB:Q3T8J9}. Note=Localizes to histone locus bodies (HLB). {ECO:0000250|UniProtKB:Q3T8J9}.
uniprot
proteins