Kw 0640
cv_term_accession
KW-0640
canonical
uniprot_keyword
KW-0640
canonical
name
Prion
uniprot
definition
Protein which is able to form a prion, a self-propagating protein conformation (infectious protein). Formation of prions involves conversion of the native proteins into an infectious, amyloid form. This class of proteins includes the members of the prion family which can form proteinaceous infectious particles responsible for transmissible spongiform encephalopathies (TSE) in many animals, such as Kuru and Creutzfeldt-Jakob syndrome in humans, scrapies in sheep and BSE in cattle. These prion diseases represent special cases of neurodegenerative amyloidoses, because they result from the transmissibility and infectivity of the amyloid.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords