Smarcd2
entrez
83796
canonical
uniprot
Q99JR8
canonical
ensembl
ENSMUSG00000078619
resolver
ensp
ENSMUSP00000021052
resolver
ensp
ENSMUSP00000102456
resolver
ensp
ENSMUSP00000167455
resolver
genesymbol
Smarcd2
resolver
genesymbol_syn
Baf60b
resolver
uniprot
B1ARI7
resolver
uniprot
B1ARJ6
resolver
uniprot
Q3TXH6
resolver
uniprot_entry
Q3TXH6_MOUSE
resolver
uniprot_entry
SMRD2_MOUSE
resolver
uniprot_sec
B1ARI7
resolver
uniprot_sec
B1ARJ6
resolver
amino_acid_sequence
MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPSPALRGPGPSGGMGVPGAAAFRPMGPAGPAAQYQRPGMSPGSRMPMAGLQVGPPAGSPFGTAAPLRPGMPPTMMDPFRKRLLVPQAQPPMPAQRRGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKADGDNAGTAGTPGGTPAADKVASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTEPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIRLT
uniprot
proteins
function
FUNCTION: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation. {ECO:0000250|UniProtKB:Q92925}.
uniprot
proteins
mass_dalton
59085
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated through a signaling process involving RAC1 and the RING finger protein UNKL. {ECO:0000250|UniProtKB:Q92925}.
uniprot
proteins
protein_family
SMARCD family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
531
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q92925}.
uniprot
proteins