PEBP1
entrez
5037
canonical
uniprot
P30086
canonical
ensembl
ENSG00000089220
resolver
ensp
ENSP00000261313
resolver
enst
ENST00000261313
resolver
genesymbol
HEL-S-34
resolver
genesymbol
PEBP1
resolver
genesymbol_syn
PBP
resolver
genesymbol_syn
PEBP
resolver
hgnc
HGNC:8630
resolver
uniprot
B2R4S1
resolver
uniprot
D9IAI1
resolver
uniprot_entry
D9IAI1_HUMAN
resolver
uniprot_entry
PEBP1_HUMAN
resolver
uniprot_sec
B2R4S1
resolver
amino_acid_sequence
MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSGK
uniprot
proteins
function
FUNCTION: Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. {ECO:0000250, ECO:0000269|PubMed:18294816}.; FUNCTION: HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
21057
uniprot
proteins
protein_family
Phosphatidylethanolamine-binding protein family
uniprot
proteins
pubmed
10490027
uniprot
proteins
pubmed
10622376
uniprot
proteins
pubmed
1286669
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18294816
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
21831839
uniprot
proteins
pubmed
22905912
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
7637590
uniprot
proteins
pubmed
7807553
uniprot
proteins
pubmed
8144042
uniprot
proteins
pubmed
9782050
uniprot
proteins
sequence_length
187
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins