Rbm22
entrez
307410
canonical
uniprot
Q4V7D7
canonical
ensembl
ENSRNOG00000019235
resolver
ensembl
ENSRNOG00055014192
resolver
ensembl
ENSRNOG00060021033
resolver
ensembl
ENSRNOG00065022804
resolver
ensp
ENSRNOP00000026087
resolver
ensp
ENSRNOP00055019929
resolver
ensp
ENSRNOP00060030001
resolver
ensp
ENSRNOP00065031592
resolver
enst
ENSRNOT00000026087
resolver
enst
ENSRNOT00055024393
resolver
enst
ENSRNOT00060036448
resolver
enst
ENSRNOT00065038936
resolver
genesymbol
Rbm22
resolver
uniprot_entry
RBM22_RAT
resolver
amino_acid_sequence
MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYYTQNMEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTVTVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHLFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP
uniprot
proteins
function
FUNCTION: Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. {ECO:0000250|UniProtKB:Q9NW64}.
uniprot
proteins
mass_dalton
46864
uniprot
proteins
protein_family
SLT11 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
420
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NW64}. Cytoplasm {ECO:0000250|UniProtKB:Q9NW64}. Note=Nearly exclusively nuclear. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol. {ECO:0000250|UniProtKB:Q9NW64}.
uniprot
proteins