Arl8a
entrez
68724
canonical
uniprot
Q8VEH3
canonical
ensembl
ENSMUSG00000026426
resolver
ensp
ENSMUSP00000027684
resolver
ensp
ENSMUSP00000121545
resolver
enst
ENSMUST00000027684
resolver
genesymbol
Arl8a
resolver
genesymbol_syn
Arl10b
resolver
genesymbol_syn
Gie2
resolver
uniprot
Q99KS1
resolver
uniprot
Q9CTB0
resolver
uniprot_entry
ARL8A_MOUSE
resolver
uniprot_sec
Q99KS1
resolver
uniprot_sec
Q9CTB0
resolver
amino_acid_sequence
MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLAGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS
uniprot
proteins
function
FUNCTION: Plays a role in lysosomes motility (PubMed:30174114). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (PubMed:30174114). May play a role in chromosome segregation (By similarity). {ECO:0000250|UniProtKB:Q9NVJ2, ECO:0000269|PubMed:30174114}.
uniprot
proteins
mass_dalton
21390
uniprot
proteins
protein_family
Arf family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15331635
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30174114
uniprot
proteins
sequence_length
186
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Late endosome membrane {ECO:0000250|UniProtKB:Q9NVJ2}. Lysosome membrane {ECO:0000250|UniProtKB:Q9CQW2}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9NVJ2}. Cell projection, axon {ECO:0000250|UniProtKB:Q9CQW2}. Synapse {ECO:0000250|UniProtKB:Q9CQW2}. Note=Localizes with microtubules at the spindle mid-zone during mitosis. {ECO:0000250|UniProtKB:Q9NVJ2}.
uniprot
proteins