Hmgcs1
entrez
29637
canonical
uniprot
P17425
canonical
ensembl
ENSRNOG00000016552
resolver
ensembl
ENSRNOG00055006312
resolver
ensembl
ENSRNOG00060014461
resolver
ensembl
ENSRNOG00065021397
resolver
ensp
ENSRNOP00000092234
resolver
ensp
ENSRNOP00000093563
resolver
ensp
ENSRNOP00055007942
resolver
ensp
ENSRNOP00060019716
resolver
ensp
ENSRNOP00065029330
resolver
enst
ENSRNOT00000100742
resolver
enst
ENSRNOT00055010259
resolver
enst
ENSRNOT00060024752
resolver
enst
ENSRNOT00065036401
resolver
genesymbol
Hmgcs1
resolver
genesymbol_syn
Hmgcs
resolver
uniprot
A0A8I6AX76
resolver
uniprot_entry
A0A8I6AX76_RAT
resolver
uniprot_entry
HMCS1_RAT
resolver
amino_acid_sequence
MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYASGNARPTGGVGAVALLIGPNAPVIFDRGLRGTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFTLNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASAELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAPDVFAENMKLREDTHHLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARRPSTNDHSLDEGVGLVHSNTATEHIPSPAKKVPRLPATSGEPESAVISNGEH
uniprot
proteins
ec_number
2.3.3.10
uniprot
proteins
function
FUNCTION: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis. {ECO:0000250|UniProtKB:P13704}.
uniprot
proteins
mass_dalton
57434
uniprot
proteins
pathway_participation
PATHWAY: Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3.
uniprot
proteins
protein_family
HMG-CoA synthase family
uniprot
proteins
protein_family
Thiolase-like superfamily
uniprot
proteins
pubmed
1972979
uniprot
proteins
sequence_length
520
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P13704}.
uniprot
proteins