TMOD4
entrez
29765
canonical
uniprot
Q9NZQ9
canonical
ensembl
ENSG00000163157
resolver
ensp
ENSP00000295314
resolver
ensp
ENSP00000615687
resolver
genesymbol
TMOD4
resolver
hgnc
HGNC:11874
resolver
uniprot
B7Z6N9
resolver
uniprot
Q5JR83
resolver
uniprot
Q8WVL3
resolver
uniprot
Q9UKH2
resolver
uniprot_entry
TMOD4_HUMAN
resolver
uniprot_sec
B7Z6N9
resolver
uniprot_sec
Q5JR83
resolver
uniprot_sec
Q8WVL3
resolver
uniprot_sec
Q9UKH2
resolver
amino_acid_sequence
MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREIPAEEQITLEPELEEALAHATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQKKR
uniprot
proteins
function
FUNCTION: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
uniprot
proteins
mass_dalton
39335
uniprot
proteins
protein_family
Tropomodulin family
uniprot
proteins
pubmed
10497209
uniprot
proteins
pubmed
10662549
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
25250574
uniprot
proteins
sequence_length
345
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:25250574}. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574). {ECO:0000269|PubMed:25250574}.
uniprot
proteins