Stxbp2
entrez
81804
canonical
uniprot
Q62753
canonical
ensembl
ENSRNOG00000000994
resolver
ensp
ENSRNOP00000081592
resolver
ensp
ENSRNOP00000099330
resolver
enst
ENSRNOT00000115749
resolver
genesymbol
Stxbp2
resolver
genesymbol_syn
Unc18b
resolver
uniprot
A0A8I5ZT02
resolver
uniprot_entry
A0A8I5ZT02_RAT
resolver
uniprot_entry
STXB2_RAT
resolver
amino_acid_sequence
MAPLGLKAVVVEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKRREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAGERGRQLDVLAQQIATLCATLQEYPSIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLHIEQDTYRYETTGLSESREKAVLLDEDDDLWVELRHMHIADVSKKVTELLKTFCESKRLTTDKANIKDLSHILKKMPQYQKELNKYSTHLHLADDCMKHFKGSVEKLCGVEQDLAMGSDAEGEKIKDTMKLIVPVLLDASVPPYDKIRVLLLYILLRNGVSEENLAKLIQHANVQSYSNLIRNLEQLGGTVTNSAGSGTSSRLERRERMEPTYQLSRWSPVIKDVMEDVVEDRLDRKLWPFVSDPAPVSSSQAAVSSARFGHWHKNKAGIEARAGPRLIVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLRTLDQKLEDIALP
uniprot
proteins
function
FUNCTION: Functions in intracellular vesicle trafficking through interaction with SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) which are essential proteins for membrane fusion. By promoting the assembly of functional STX11/SNAP23/VAMP8 SNARE complexes at the plasma membrane, regulates cytotoxic granule exocytosis in natural killer (NK) cells. {ECO:0000250|UniProtKB:Q15833}.
uniprot
proteins
mass_dalton
66696
uniprot
proteins
protein_family
STXBP/unc-18/SEC1 family
uniprot
proteins
pubmed
7768895
uniprot
proteins
sequence_length
594
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q15833}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q15833}. Cytolytic granule membrane {ECO:0000250|UniProtKB:Q15833}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q15833}. Note=Enriched at the immunological synapse in activated immune cells. {ECO:0000250|UniProtKB:Q15833}.
uniprot
proteins