P0C172
uniprot
P0C172
canonical
amino_acid_sequence
METCQMSRSPRERLLLLLLLLLLVPWGTGPASGVALPLAGVFSLRAPGRAWAGLGSPLSRRSLALADDAAFRERARLLAALERRRWLDSYMQKLLLLDAP
uniprot
proteins
function
FUNCTION: Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action of PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits. {ECO:0000269|PubMed:12559132}.
uniprot
proteins
mass_dalton
11022
uniprot
proteins
protein_family
Parathyroid hormone family
uniprot
proteins
pubmed
11818570
uniprot
proteins
pubmed
12508326
uniprot
proteins
pubmed
12559132
uniprot
proteins
sequence_length
100
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins