THADA
entrez
63892
canonical
uniprot
Q6YHU6
canonical
ensembl
ENSG00000115970
resolver
ensp
ENSP00000384266
resolver
ensp
ENSP00000385995
resolver
ensp
ENSP00000386088
resolver
ensp
ENSP00000525691
resolver
ensp
ENSP00000525692
resolver
ensp
ENSP00000525693
resolver
ensp
ENSP00000749952
resolver
genesymbol
THADA
resolver
genesymbol_syn
GITA
resolver
genesymbol_syn
KIAA1767
resolver
hgnc
HGNC:19217
resolver
uniprot
A8K1V8
resolver
uniprot
B7WNS6
resolver
uniprot
Q3KR04
resolver
uniprot
Q53RC6
resolver
uniprot
Q53TB2
resolver
uniprot
Q6YHU2
resolver
uniprot
Q6ZU38
resolver
uniprot
Q8IY32
resolver
uniprot
Q8TAU8
resolver
uniprot
Q96I88
resolver
uniprot
Q9BZF7
resolver
uniprot
Q9C096
resolver
uniprot
Q9H6U0
resolver
uniprot
Q9H6W7
resolver
uniprot_entry
THADA_HUMAN
resolver
uniprot_sec
A8K1V8
resolver
uniprot_sec
B7WNS6
resolver
uniprot_sec
Q3KR04
resolver
uniprot_sec
Q53RC6
resolver
uniprot_sec
Q53TB2
resolver
uniprot_sec
Q6YHU2
resolver
uniprot_sec
Q6ZU38
resolver
uniprot_sec
Q8IY32
resolver
uniprot_sec
Q8TAU8
resolver
uniprot_sec
Q96I88
resolver
uniprot_sec
Q9BZF7
resolver
uniprot_sec
Q9C096
resolver
uniprot_sec
Q9H6U0
resolver
uniprot_sec
Q9H6W7
resolver
amino_acid_sequence
MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQLTDGVSQIHYIKQIVPLLEKADKNGMCDPTIQSCLDILAGIYLSLSLKNPLKKVLASSLNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLKNVLHFLQKSLIEILEENRKCAGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKTSDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEKIPHLISSVLLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLLDTAHVLFTLSSQIKEPTLEMFLSRILASWTNSAIQVLESSSPSLTDSLNGNSSIVGRLLEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWHIKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRNHKSHLKSQTAESSWIDQWHETWVSPLLFILCEGNLDQKSYVIDYYLPKLLSYSPESLQYMVKILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDARIKQGLIHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILAFDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIPMDTDSESASRLQMILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDTSTEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLKITMKELISLAGPTDDIQSTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMRCGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDITVCTKAKLWLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGIISGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAKSGERETNVPISFSQLLESAFPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKILHCMDPGEWLPQTEHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLFLTNPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILLGWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPAAEFVKTVEFTRLRIQEERTLACLRLLAFLEGKEGEDTLVLSVWDSYAESRQLTLPRTEAAC
uniprot
proteins
disease_involvement
DISEASE: Note=Chromosomal aberrations involving THADA have been observed in benign thyroid adenomas. Translocation t(2;3)(p21;p25) and translocation t(2;7)(p21;p15); the sequences derived from chromosomes 3p25 and 7p15 do not appear to include a coding region and the fusion events probably result in truncated THADA proteins.
uniprot
proteins
function
FUNCTION: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs. {ECO:0000269|PubMed:25404562}.
uniprot
proteins
mass_dalton
219607
uniprot
proteins
protein_family
THADA family
uniprot
proteins
pubmed
11214970
uniprot
proteins
pubmed
12955091
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17889454
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25404562
uniprot
proteins
sequence_length
1953
uniprot
proteins