P56700
uniprot
P56700
canonical
amino_acid_sequence
MCRTIATFPNTCLERAKEFKTRLGIFLHKSELSSDTGGNGKFEWASKLSKERSFSEDVLGWRESFQSLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASATSASGSSPAEPSHT
uniprot
proteins
function
FUNCTION: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals. {ECO:0000250|UniProtKB:P97428}.
uniprot
proteins
mass_dalton
22400
uniprot
proteins
post_translational_modification
PTM: Palmitoylated on Cys-2 and/or Cys-12. {ECO:0000250|UniProtKB:P97428}.; PTM: Phosphorylated. Phosphorylation at Tyr-167 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1. {ECO:0000250|UniProtKB:O15492}.
uniprot
proteins
pubmed
8917514
uniprot
proteins
sequence_length
199
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:P97428}; Lipid-anchor {ECO:0000250|UniProtKB:P97428}.
uniprot
proteins