MCUR1
entrez
63933
canonical
uniprot
Q96AQ8
canonical
ensembl
ENSG00000050393
resolver
ensp
ENSP00000368468
resolver
ensp
ENSP00000670724
resolver
genesymbol
C6orf79
resolver
genesymbol
MCUR1
resolver
genesymbol_syn
C6orf79
resolver
genesymbol_syn
CCDC90A
resolver
hgnc
HGNC:21097
resolver
uniprot
A0A384NPW7
resolver
uniprot
Q96JS7
resolver
uniprot
Q9H7F8
resolver
uniprot_entry
A0A384NPW7_HUMAN
resolver
uniprot_entry
MCUR1_HUMAN
resolver
uniprot_sec
Q96JS7
resolver
uniprot_sec
Q9H7F8
resolver
amino_acid_sequence
MDCGSVGGQRTQRLPGRQRLLFLPVGLSGRPGGSETSARRCLSALSDGLGALRPRAPAARGGVSRASPLLLLLLVPSPRLAAAAPRRQLGDWERSRLGYAAPPAGRSSAWRCSPGVAAAAGALPQYHGPAPALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIVSALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKIKLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDRALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLWI
uniprot
proteins
function
FUNCTION: Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion (PubMed:23178883, PubMed:26445506, PubMed:26976564, PubMed:27184846). Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU (PubMed:23178883). Probably involved in the assembly of the membrane components of the uniporter complex (uniplex) (PubMed:27184846). {ECO:0000269|PubMed:23178883, ECO:0000269|PubMed:26445506, ECO:0000269|PubMed:26976564, ECO:0000269|PubMed:27184846}.
uniprot
proteins
mass_dalton
39694
uniprot
proteins
protein_family
CCDC90 family
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23178883
uniprot
proteins
pubmed
25565209
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26341627
uniprot
proteins
pubmed
26445506
uniprot
proteins
pubmed
26976564
uniprot
proteins
pubmed
27184846
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:23178883}; Multi-pass membrane protein {ECO:0000269|PubMed:23178883}.
uniprot
proteins
transmembrane_region
TRANSMEM 69..85; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 339..358; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins