O08843
uniprot
O08843
canonical
amino_acid_sequence
MSDDNGSGNNCTTNHFLLYGSLGLGGLLLLLVIILFICLCGFSQRVKRLERNAQVSGQEPHYASLQQLPVSSSDITDMKEDLSTDYACIARSTPT
uniprot
proteins
function
FUNCTION: Possible role in modulating immune responses. Has an inhibitory effect on lymphocyte proliferation. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. {ECO:0000250|UniProtKB:O00453, ECO:0000269|PubMed:11478849, ECO:0000303|PubMed:11478849}.
uniprot
proteins
mass_dalton
10325
uniprot
proteins
protein_family
LST1 family
uniprot
proteins
pubmed
11478849
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
3117682
uniprot
proteins
pubmed
9367684
uniprot
proteins
sequence_length
95
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins