FAR2
entrez
55711
canonical
uniprot
Q96K12
canonical
ensembl
ENSG00000064763
resolver
ensp
ENSP00000182377
resolver
ensp
ENSP00000443291
resolver
ensp
ENSP00000449349
resolver
genesymbol
FAR2
resolver
genesymbol
HEL-S-81
resolver
genesymbol_syn
MLSTD1
resolver
hgnc
HGNC:25531
resolver
uniprot
A0A024RAW7
resolver
uniprot
B2RBI0
resolver
uniprot
F8VV73
resolver
uniprot
Q9H0D5
resolver
uniprot
Q9NUX8
resolver
uniprot
Q9NVW8
resolver
uniprot_entry
A0A024RAW7_HUMAN
resolver
uniprot_entry
B2RBI0_HUMAN
resolver
uniprot_entry
FACR2_HUMAN
resolver
uniprot_entry
Q9NUX8_HUMAN
resolver
uniprot_sec
F8VV73
resolver
uniprot_sec
Q9H0D5
resolver
uniprot_sec
Q9NVW8
resolver
amino_acid_sequence
MSTIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPKLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTLVYHITSGNMNPCNWHKMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTKLMNRLLRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLKEDMAGIPKAKQRLKRLRNIHYLFNTALFLIAWRLLIARSQMARNVWFFIVSFCYKFLSYFRASSTLKV
uniprot
proteins
ec_number
1.2.1.84
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols (FAls) (PubMed:15220348). A lower activity can be observed with shorter fatty acyl-CoA substrates (PubMed:15220348). Can produce very long-chain and ultra long-chain FAls, regardless of whether they have a straight or branched chain (PubMed:35238077). Involved in the production of ether lipids/plasmalogens and wax monoesters whose synthesis requires FAls as substrates (PubMed:24108123, PubMed:35238077). {ECO:0000269|PubMed:15220348, ECO:0000269|PubMed:24108123, ECO:0000269|PubMed:35238077}.
uniprot
proteins
mass_dalton
59438
uniprot
proteins
protein_family
Fatty acyl-CoA reductase family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15220348
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
24108123
uniprot
proteins
pubmed
35238077
uniprot
proteins
sequence_length
515
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000269|PubMed:15220348, ECO:0000269|PubMed:24108123}; Single-pass membrane protein {ECO:0000305|PubMed:24108123}.
uniprot
proteins
transmembrane_region
TRANSMEM 465..484; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins