MIB2
entrez
142678
canonical
uniprot
Q96AX9
canonical
ensembl
ENSG00000197530
resolver
ensp
ENSP00000348081
resolver
ensp
ENSP00000367984
resolver
ensp
ENSP00000426103
resolver
ensp
ENSP00000426128
resolver
ensp
ENSP00000427680
resolver
ensp
ENSP00000428264
resolver
ensp
ENSP00000428660
resolver
ensp
ENSP00000559233
resolver
ensp
ENSP00000628600
resolver
ensp
ENSP00000628602
resolver
ensp
ENSP00000628617
resolver
ensp
ENSP00000628629
resolver
ensp
ENSP00000628648
resolver
enst
ENST00000355826
resolver
enst
ENST00000504599
resolver
enst
ENST00000505820
resolver
enst
ENST00000518681
resolver
enst
ENST00000520777
resolver
genesymbol
MIB2
resolver
genesymbol_syn
SKD
resolver
genesymbol_syn
ZZANK1
resolver
hgnc
HGNC:30577
resolver
uniprot
A0A8C8N694
resolver
uniprot
A0A8C8USR6
resolver
uniprot
A2AGM5
resolver
uniprot
A2AGM6
resolver
uniprot
B3KV93
resolver
uniprot
B3KVF4
resolver
uniprot
B3KXY1
resolver
uniprot
B4DZ57
resolver
uniprot
E9PD12
resolver
uniprot
E9PGU1
resolver
uniprot
E9PHQ1
resolver
uniprot
F8WA73
resolver
uniprot
J3KNZ7
resolver
uniprot
Q7Z437
resolver
uniprot
Q8IY62
resolver
uniprot
Q8N786
resolver
uniprot
Q8N897
resolver
uniprot
Q8N8R2
resolver
uniprot
Q8N911
resolver
uniprot
Q8NB36
resolver
uniprot
Q8NCY1
resolver
uniprot
Q8NG59
resolver
uniprot
Q8NG60
resolver
uniprot
Q8NG61
resolver
uniprot
Q8NI59
resolver
uniprot
Q8WYN1
resolver
uniprot_entry
A0A8C8N694_HUMAN
resolver
uniprot_entry
A0A8C8USR6_HUMAN
resolver
uniprot_entry
E9PD12_HUMAN
resolver
uniprot_entry
MIB2_HUMAN
resolver
uniprot_sec
A2AGM5
resolver
uniprot_sec
A2AGM6
resolver
uniprot_sec
B3KV93
resolver
uniprot_sec
B3KVF4
resolver
uniprot_sec
B3KXY1
resolver
uniprot_sec
B4DZ57
resolver
uniprot_sec
E9PGU1
resolver
uniprot_sec
E9PHQ1
resolver
uniprot_sec
F8WA73
resolver
uniprot_sec
J3KNZ7
resolver
uniprot_sec
Q7Z437
resolver
uniprot_sec
Q8IY62
resolver
uniprot_sec
Q8N786
resolver
uniprot_sec
Q8N897
resolver
uniprot_sec
Q8N8R2
resolver
uniprot_sec
Q8N911
resolver
uniprot_sec
Q8NB36
resolver
uniprot_sec
Q8NCY1
resolver
uniprot_sec
Q8NG59
resolver
uniprot_sec
Q8NG60
resolver
uniprot_sec
Q8NG61
resolver
uniprot_sec
Q8NI59
resolver
uniprot_sec
Q8WYN1
resolver
amino_acid_sequence
MDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGGVGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICDCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRIPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYRVGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVLREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGDVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCLVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGTPNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSKKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAPCGSALSACPICRQPIRDRIQIFV
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. {ECO:0000250|UniProtKB:Q8R516}.
uniprot
proteins
mass_dalton
103658
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated. Possibly via autoubiquitination (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
12761501
uniprot
proteins
pubmed
14507647
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
955
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14507647}. Endosome {ECO:0000269|PubMed:14507647}. Note=Colocalizes with endosomal compartments.
uniprot
proteins