MED22
entrez
6837
canonical
uniprot
Q15528
canonical
ensembl
ENSG00000148297
resolver
ensembl
ENSG00000281022
resolver
ensp
ENSP00000342343
resolver
ensp
ENSP00000478773
resolver
genesymbol
MED22
resolver
genesymbol_syn
SURF5
resolver
hgnc
HGNC:11477
resolver
uniprot
B3KW83
resolver
uniprot
B3KWX4
resolver
uniprot
O76072
resolver
uniprot
Q5T8U0
resolver
uniprot_entry
MED22_HUMAN
resolver
uniprot_sec
B3KW83
resolver
uniprot_sec
B3KWX4
resolver
uniprot_sec
O76072
resolver
uniprot_sec
Q5T8U0
resolver
amino_acid_sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRTLQEECDRKLITLRDEISIDLYELEEEYYSSSSSLCEANDLPLCEAYGRLDLDTDSADGLSAPLLASPEPSAGPLQVAAPAHSHAGGPGPTEHA
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
uniprot
proteins
mass_dalton
22221
uniprot
proteins
protein_family
Mediator complex subunit 22 family
uniprot
proteins
pubmed
11891058
uniprot
proteins
pubmed
12584197
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15989967
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
8586415
uniprot
proteins
sequence_length
200
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins