Pcsk7
entrez
29606
canonical
uniprot
Q62849
canonical
ensembl
ENSRNOG00000017478
resolver
ensembl
ENSRNOG00055020296
resolver
ensembl
ENSRNOG00060013837
resolver
ensembl
ENSRNOG00065027666
resolver
ensp
ENSRNOP00000023677
resolver
ensp
ENSRNOP00055028094
resolver
ensp
ENSRNOP00060018792
resolver
ensp
ENSRNOP00065039110
resolver
enst
ENSRNOT00000023677
resolver
enst
ENSRNOT00055034669
resolver
enst
ENSRNOT00060023640
resolver
enst
ENSRNOT00065047686
resolver
genesymbol
Pcsk7
resolver
genesymbol_syn
Pc7
resolver
uniprot_entry
PCSK7_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by zinc and copper.
uniprot
proteins
amino_acid_sequence
MPKGRQKVPRLDARLGLPICLCLELAIFFLVPQVMGLTEAGGLDTLGAGGLSWAVHLDSLEGERKEESLIQQANAVAQAAGLVNAGRIGELQGHYLFVQPAGHGQAMEAEAMRQQAEAVLAKHEAVRWHSEQRLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDHRADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGVYRLVIRDVGDEPLQVGILQQWQLTLYGSTWSPVDIKDRQSLLESAMSGKYLHDDFTLPCPPGLKIPEEDGYSITPNTLKTLVLVGCFSVFWTIYYMLEVCLSQRSKASTHGCRRGCCPWPPQSQNSKEVGTALESMPLCSSKDLDGVDSEHGDCTTASSLLAPELLGEADWSLSQNSKSDLDCPPHQPPDLKDGQIC
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway.
uniprot
proteins
mass_dalton
85599
uniprot
proteins
protein_family
Peptidase S8 family
uniprot
proteins
pubmed
8622945
uniprot
proteins
sequence_length
783
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Seems to be localized intracellularly to the trans Golgi network.
uniprot
proteins
transmembrane_region
TRANSMEM 667..687; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins