Abca17
entrez
287112
canonical
uniprot
E9PU17
canonical
ensembl
ENSRNOG00000039656
resolver
ensp
ENSRNOP00000057544
resolver
ensp
ENSRNOP00000086705
resolver
enst
ENSRNOT00000060818
resolver
genesymbol
Abca17
resolver
uniprot
Q4H493
resolver
uniprot_entry
ABCAH_RAT
resolver
uniprot_sec
Q4H493
resolver
amino_acid_sequence
MAPFKKLKLLLWKNFVLKKRKTLVTVLETLMPVLFSAIVLYLRLNSMPRNKANTNYPAVDVSLLPVYFHNYPLKSKFQLVYIPSKSETLKAVTEVVEQTFAVDFEVLGFPSVSLFENYIIKDPKSFYVLVGIVFHHDFNSSNEPLPLVVKYDLRFSYVQRNSISPPRHLFFQEDIEGWCTAFLYPPNLSQAPREFSYADGGHPGYNKEGFLAIQHAVDKAIMLHHAPKAALDMFKNLQVSVQRFPSGSHIQDPFLVILQNEFPLLLMLSFICVELIITNSILLEKERKQKEYMYLMGLENWLHWVAWFITFFLSALVTVSGMTVLFCTKMNGVAVFRNSNTTLIFIFLMCFAIATIFFAFMMSTFFQRAHVGTVIGGIVFFFTYLPYMYITFSYHQRTYSQKILSCLFSNVAMAMGVRFISLFEAEGTGIQWRNMGSVWGDFSFTQVLVMLLLDSFLYCLVAFLVESLFPRKIGMPKSWYIFAKCPLWRKKSFPVIPPLLVIGDPEKTSKGDFLQDEPAGHINAIEIQHLYKVFYTGRSKCIAVKDLSMNLYKGQITVLLGHNGAGKTTVCSVLTGLIPPSKGHAYIHGCEISKDMVRIRKNVGWCPQHDILFDNFTVTDHLYFYGQLKGLSHQDCHEKIEEMLHTLGLEDKRNSRSKFLSGGIKRKLAIGIALIAGSKVLILDEPTSGMDSSSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGTPSFLKQKYGAGYYMTIIKTPLCDTEKLAKVIYHHIPNAILESRIGEEMIFTLPKKAMPRFEALFADLEQRQTELGISTFGASVTTMEEVFIRVCKLADPSTNVLTEKRPSLRHLPRNHRVPVDRIKCLHSRIFSLSSDQPIRLNTGFSLLCQQFYAMLLKKVAFSRRNWMLVLSVQILLPLVIIMLSLSFFNFKLRKLDNVPLELTLQTYGQTIVPFFIAENSRLDPQLSDNFVKMLVAAGQVPLRIQGSVENFLLKKAKEAPEDFDKLYVVAASFEDVNDHTTVKALFNNQAYHSPSLALALVDNVLFKLLSGANASITTTNYPQPQTAMELSETILYQGPKGHYLVVNFLFGIAFLSSSFSILTVGEKSIKSKNLQFLSGVSMAAFWLSALLWDLISFLVPTLLLVLVFFWYKEEAFAHPQSIPAVVLIMMLYGWAIIPLVYTVSFSFKTPGSGCVKLVAMLTFLSISPVVLVTVTSEKDLGYTELSDTLDHIFLIFPGHCLGMAFSNLYYNFEIKKFCNAKNLSDIDCNDVLEGYVVQKNIYAWESLGIGKYLTALAILGPVYITLLFLTEANAFCALKARLSGFFCKQKLRMLLNVTGAEDEDVLEEAENIKYHLDTLIKKSPLVVKELSKVYKEKVPLLAVNKVSFVVKEKECFGLLGLNGAGKTSIFNMLTREQPITSGDAFVKGFNIRTDMAKVQQWIGYCPEFDALLNFMTGREMLVMHARIRGIPECHIKTCVDMILENLLMCVYADKLVKTYSDGNKRVLSTAIALLGEPTVILLDEPSTGMDPVARRLVWDAVGRVRESGKTIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSRFGSGYSLQAKVRRKWQQQMLEEFKAFVDLTFPGSSLEDEHQSMVQYYLPGQNLSWAKVFGIMEQAKKDYVLEDYSISQLSLEDIFLSFTRPVPDTKENIQQGQAALDSSLSPSNSRPISSPPSSPPSSPPSSPPSRPPSRPSQPPSRPPSRHPSSPSQPPSRPPSRHPSSPSQPPSEPVLL
uniprot
proteins
function
FUNCTION: Promotes cholesterol efflux from sperm which renders sperm capable of fertilization. Has also been shown to decrease levels of intracellular esterified neutral lipids including cholesteryl esters, fatty acid esters and triacylglycerols. {ECO:0000250|UniProtKB:E9PX95}.
uniprot
proteins
mass_dalton
199859
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:E9PX95}.
uniprot
proteins
protein_family
ABC transporter superfamily
uniprot
proteins
protein_family
ABCA family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15810880
uniprot
proteins
sequence_length
1773
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:E9PX95}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:E9PX95}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 262..282; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 306..326; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 342..362; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 372..392; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 403..423; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 444..464; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 912..932; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1088..1108; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1134..1154; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1166..1186; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1198..1218; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1236..1256; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1293..1313; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins