LRRFIP1
entrez
9208
canonical
uniprot
Q32MZ4
canonical
ensembl
ENSG00000124831
resolver
ensp
ENSP00000244815
resolver
ensp
ENSP00000289175
resolver
ensp
ENSP00000310109
resolver
ensp
ENSP00000375857
resolver
ensp
ENSP00000533768
resolver
ensp
ENSP00000533771
resolver
ensp
ENSP00000533779
resolver
ensp
ENSP00000533781
resolver
ensp
ENSP00000533786
resolver
ensp
ENSP00000640932
resolver
ensp
ENSP00000640937
resolver
ensp
ENSP00000640975
resolver
ensp
ENSP00000640982
resolver
ensp
ENSP00000640983
resolver
ensp
ENSP00000656433
resolver
ensp
ENSP00000656434
resolver
ensp
ENSP00000727725
resolver
ensp
ENSP00000727726
resolver
ensp
ENSP00000727733
resolver
ensp
ENSP00000727736
resolver
ensp
ENSP00000727739
resolver
ensp
ENSP00000760153
resolver
ensp
ENSP00000760154
resolver
ensp
ENSP00000760156
resolver
genesymbol
LRRFIP1
resolver
genesymbol_syn
GCF2
resolver
genesymbol_syn
TRIP
resolver
hgnc
HGNC:6702
resolver
uniprot
A0A0F7NGI8
resolver
uniprot
B4DPC0
resolver
uniprot
E9PGZ2
resolver
uniprot
O75766
resolver
uniprot
O75799
resolver
uniprot
Q32MZ5
resolver
uniprot
Q53T49
resolver
uniprot
Q6PKG2
resolver
uniprot
Q9Y607
resolver
uniprot_entry
A0A0F7NGI8_HUMAN
resolver
uniprot_entry
B4DPC0_HUMAN
resolver
uniprot_entry
LRRF1_HUMAN
resolver
uniprot_sec
E9PGZ2
resolver
uniprot_sec
O75766
resolver
uniprot_sec
O75799
resolver
uniprot_sec
Q32MZ5
resolver
uniprot_sec
Q53T49
resolver
uniprot_sec
Q6PKG2
resolver
uniprot_sec
Q9Y607
resolver
amino_acid_sequence
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKEDCTMS
uniprot
proteins
function
FUNCTION: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. {ECO:0000269|PubMed:10364563, ECO:0000269|PubMed:14522076, ECO:0000269|PubMed:16199883, ECO:0000269|PubMed:19265123, ECO:0000269|PubMed:9705290}.
uniprot
proteins
mass_dalton
89253
uniprot
proteins
protein_family
LRRFIP family
uniprot
proteins
pubmed
10364563
uniprot
proteins
pubmed
10366446
uniprot
proteins
pubmed
14522076
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16199883
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19265123
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23099021
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25114211
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
9671805
uniprot
proteins
pubmed
9705290
uniprot
proteins
sequence_length
808
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm.
uniprot
proteins