P30938
uniprot
P30938
canonical
amino_acid_sequence
MEPLSLASTPSWNASAASSGNHNWSLVGSASPMGARAVLVPVLYLLVCTVGLSGNTLVIYVVLRHAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKMASAAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRRSEPKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKVLCLRRGYGMEDADAIEPRPDKSGRPQATLPTRSCEANGLMQTSRI
uniprot
proteins
function
FUNCTION: Receptor for somatostatin-28. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization. {ECO:0000269|PubMed:1362243, ECO:0000269|PubMed:7908405}.
uniprot
proteins
mass_dalton
39971
uniprot
proteins
post_translational_modification
PTM: Palmitoylated at Cys-320 by ZDHHC5, but not ZDHHC8. Palmitoylation creates an additional intracellular loop which is thought to be important for efficient coupling to G proteins and may target the protein to lipid rafts (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
1362243
uniprot
proteins
pubmed
21820437
uniprot
proteins
pubmed
7908405
uniprot
proteins
sequence_length
363
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 36..63; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 74..99; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 112..133; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 156..176; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 197..221; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 248..273; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 284..308; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins