Slc52a2
entrez
362942
canonical
uniprot
B5MEV3
canonical
ensembl
ENSRNOG00000032561
resolver
ensembl
ENSRNOG00065028567
resolver
ensp
ENSRNOP00000046721
resolver
ensp
ENSRNOP00065040388
resolver
enst
ENSRNOT00000047380
resolver
enst
ENSRNOT00065049251
resolver
genesymbol
Slc52a2
resolver
genesymbol_syn
Gpr172a
resolver
genesymbol_syn
Gpr172b
resolver
genesymbol_syn
Rft1
resolver
uniprot
A3KN99
resolver
uniprot_entry
S52A2_RAT
resolver
uniprot_sec
A3KN99
resolver
activity_regulation
ACTIVITY REGULATION: Riboflavin transport is Na(+)-independent but moderately pH-sensitive (By similarity). Activity is strongly inhibited by riboflavin analogs, such as lumiflavin (By similarity). Weakly inhibited by flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) (By similarity). {ECO:0000250|UniProtKB:Q9HAB3}.
uniprot
proteins
amino_acid_sequence
MAAPPLGRLVLTHLLVALFGMGSWIAVNGIWVELPVVVKELPEGWSLPSYLSVLVALGNLGLLLVTLWRRLAPGKSERIPIQVVQGLSIVGTGLLAPLWSNMALVAGQLHSVAFLTLAFVLALSCCASNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALAQGVGRLECLHVPANGTTGPPIKVSPINFPERFSAGTFFWVLTALLGTSAAAFQGLLLLLPSPPPEATMGTGLRVETPGTEEEEEEEEASPLQEPPGQVASIVSSPDPKAHRLFSSRSACLLGLLAITNALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSSANPLACFLAMAVLCRSLAGLYGLCLLGMFFGTYLMTLAVLSPCPPLVGTSAGVVLVVLSWVLCAGVFSYIKVATSSMLHSGGRPALLAAGVAIQVGSLLGAIAMFPPTSVYPVFRSGEDCVDQCGP
uniprot
proteins
function
FUNCTION: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. May also act as a receptor for 4-hydroxybutyrate. {ECO:0000250|UniProtKB:Q9HAB3}.
uniprot
proteins
mass_dalton
46956
uniprot
proteins
protein_family
Riboflavin transporter family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18632736
uniprot
proteins
pubmed
19122205
uniprot
proteins
sequence_length
450
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:18632736, ECO:0000269|PubMed:19122205}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 14..34; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 47..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 114..136; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 147..167; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 282..302; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 317..337; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 344..364; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 371..391; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 409..429; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins