Gmnc
entrez
239789
canonical
uniprot
Q3URY2
canonical
ensembl
ENSMUSG00000068428
resolver
ensp
ENSMUSP00000087269
resolver
ensp
ENSMUSP00000156070
resolver
ensp
ENSMUSP00000156264
resolver
genesymbol
Gmnc
resolver
genesymbol_syn
Gemc1
resolver
genesymbol_syn
Gm606
resolver
uniprot
Q3TUK3
resolver
uniprot
Q5RJG4
resolver
uniprot_entry
GEMC1_MOUSE
resolver
uniprot_sec
Q3TUK3
resolver
uniprot_sec
Q5RJG4
resolver
amino_acid_sequence
MNSILPCQDQYFVGGQSYNCPYSTTTSESGVDVSKETWVSFWAAGLLDNTELQQAPQVLESPSELSFPVLDSCSWEEAQLSSQLYRNKQLQDTLLQKEEELARLHEENNHLRQYLNSTLVKRLEEKAKKLLSSDEFSKVFGKLRKEKRKPKEHRHSPAEIPQFKTAKRNLSTEFSNCEEQPGPHVDPWVLQTLGLKDLNTIDDTLPANYSATTSHPRAVPSISSLFVHDANGYANVPRDLHLDYVGQGTHGSHTTSIHQEDCHSFPRLSNPPVRVQTLPYHTADVSPNKTEMAFSTSLSPHCNVKTHSFHQGQAFVRRDEEGGWKFTWVPKQT
uniprot
proteins
function
FUNCTION: Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37758
uniprot
proteins
post_translational_modification
PTM: Highly phosphorylated by CDK2; stimulates initiation of DNA replication. {ECO:0000250}.
uniprot
proteins
protein_family
GEMC1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
333
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Associates with chromatin during pre-replication complex (pre-RC) formation. {ECO:0000250}.
uniprot
proteins