Cyb5r3
entrez
25035
canonical
uniprot
P20070
canonical
ensembl
ENSRNOG00000009592
resolver
ensembl
ENSRNOG00055030420
resolver
ensembl
ENSRNOG00060029632
resolver
ensembl
ENSRNOG00065032895
resolver
ensp
ENSRNOP00000061381
resolver
ensp
ENSRNOP00000082175
resolver
genesymbol
Cyb5r3
resolver
genesymbol_syn
Dia1
resolver
uniprot
Q64569
resolver
uniprot
Q64720
resolver
uniprot_entry
NB5R3_RAT
resolver
uniprot_sec
Q64569
resolver
uniprot_sec
Q64720
resolver
amino_acid_sequence
MGAQLSTLSRVVLSPVWFVYSLFMKLFQRSSPAITLENPDIKYPLRLIDKEIISHDTRRFRFALPSPQHILGLPIGQHIYLSTRIDGNLVIRPYTPVSSDDDKGFVDLVVKVYFKDTHPKFPAGGKMSQYLENMNIGDTIEFRGPNGLLVYQGKGKFAIRADKKSNPVVRTVKSVGMIAGGTGITPMLQVIRAVLKDPNDHTVCYLLFANQSEKDILLRPELEELRNEHSSRFKLWYTVDKAPDAWDYSQGFVNEEMIRDHLPPPGEETLILMCGPPPMIQFACLPNLERVGHPKERCFTF
uniprot
proteins
ec_number
1.6.2.2
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor. {ECO:0000269|PubMed:11695905, ECO:0000269|PubMed:8812833, ECO:0000269|PubMed:8978818}.
uniprot
proteins
mass_dalton
34175
uniprot
proteins
mutagenesis
MUTAGEN 2; /note="G->A: Loss of myristoylation and localization to the mitochondrial outer membrane but no loss of enzyme activity."; /evidence="ECO:0000269|PubMed:8978818"; MUTAGEN 111; /note="K->E,Q: 2-3 fold decrease in Km for 2 Fe(III)-[cytochrome b5]."; /evidence="ECO:0000269|PubMed:11695905"; MUTAGEN 111; /note="K->R,A,H: Km for 2 Fe(III)-[cytochrome b5] similiar to that of wild-type."; /evidence="ECO:0000269|PubMed:11695905
uniprot
proteins
post_translational_modification
PTM: [Isoform 1]: Myristoylated. {ECO:0000269|PubMed:2498303, ECO:0000269|PubMed:8978818}.
uniprot
proteins
protein_family
Flavoprotein pyridine nucleotide cytochrome reductase family
uniprot
proteins
pubmed
11695905
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1577871
uniprot
proteins
pubmed
2391344
uniprot
proteins
pubmed
2498303
uniprot
proteins
pubmed
3174630
uniprot
proteins
pubmed
8143727
uniprot
proteins
pubmed
8812833
uniprot
proteins
pubmed
8978818
uniprot
proteins
sequence_length
301
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:8978818}; Lipid-anchor {ECO:0000269|PubMed:8978818}; Cytoplasmic side {ECO:0000305|PubMed:8978818}. Mitochondrion outer membrane {ECO:0000269|PubMed:8978818}; Lipid-anchor {ECO:0000269|PubMed:8978818}; Cytoplasmic side {ECO:0000305|PubMed:8978818}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:1577871}.
uniprot
proteins