DCUN1D4
entrez
23142
canonical
uniprot
Q92564
canonical
ensembl
ENSG00000109184
resolver
ensp
ENSP00000334625
resolver
ensp
ENSP00000370850
resolver
ensp
ENSP00000389900
resolver
ensp
ENSP00000426982
resolver
ensp
ENSP00000630156
resolver
ensp
ENSP00000655304
resolver
ensp
ENSP00000745781
resolver
genesymbol
DCUN1D4
resolver
genesymbol_syn
KIAA0276
resolver
hgnc
HGNC:28998
resolver
uniprot
B4DH25
resolver
uniprot
B4DH26
resolver
uniprot
Q7Z3F3
resolver
uniprot
Q7Z6B8
resolver
uniprot_entry
B4DH26_HUMAN
resolver
uniprot_entry
DCNL4_HUMAN
resolver
uniprot_sec
B4DH25
resolver
uniprot_sec
Q7Z3F3
resolver
uniprot_sec
Q7Z6B8
resolver
amino_acid_sequence
MHSDAAAVNFQLNSHLSTLANIHKIYHTLNKLNLTEDIGQDDHQTGSLRSCSSSDCFNKVMPPRKKRRPASGDDLSAKKSRHDSMYRKYDSTRIKTEEEAFSSKRCLEWFYEYAGTDDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRNTLDYLRSFLNDSTNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWPLFPVFHQFLEQSKYKVINKDQWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEWYKDKQMS
uniprot
proteins
function
FUNCTION: Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which are necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). {ECO:0000269|PubMed:23201271, ECO:0000269|PubMed:26906416}.
uniprot
proteins
mass_dalton
34068
uniprot
proteins
mutagenesis
MUTAGEN 250; /note="D->A: Does not affect localization at nucleus; when associated with R-274 and A-280."; /evidence="ECO:0000269|PubMed:26906416"; MUTAGEN 274; /note="A->R: Does not affect localization at nucleus; when associated with A-250 and A-280."; /evidence="ECO:0000269|PubMed:26906416"; MUTAGEN 280; /note="D->A: Does not affect localization at nucleus; when associated with A-250 and R-274."; /evidence="ECO:0000269|PubMed:26906416
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23201271
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
26906416
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
28581483
uniprot
proteins
pubmed
9039502
uniprot
proteins
sequence_length
292
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:26906416}.
uniprot
proteins