KLHL9
entrez
55958
canonical
uniprot
Q9P2J3
canonical
ensembl
ENSG00000198642
resolver
ensp
ENSP00000351933
resolver
ensp
ENSP00000520799
resolver
ensp
ENSP00000520800
resolver
enst
ENST00000359039
resolver
enst
ENST00000718394
resolver
enst
ENST00000718395
resolver
genesymbol
KLHL9
resolver
genesymbol_syn
KIAA1354
resolver
hgnc
HGNC:18732
resolver
uniprot
Q58EZ4
resolver
uniprot
Q8TCQ2
resolver
uniprot_entry
KLHL9_HUMAN
resolver
uniprot_entry
Q58EZ4_HUMAN
resolver
uniprot_sec
Q8TCQ2
resolver
amino_acid_sequence
MKVSLGNGEMGVSAHLQPCKAGTTRFFTSNTHSSVVLQGFDQLRIEGLLCDVTLVPGDGDEIFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKVGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRIANTYNLIEVDKYVNNFILKNFPALLSTGEFLKLPFERLAFVLSSNSLKHCTELELFKAACRWLRLEDPRMDYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSDRTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDERAQEWRSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRSAAGELATVECYNPRMNEWSYVAKMSEPHYGHAGTVYGGLMYISGGITHDTFQNELMCFDPDTDKWMQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSPTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEENPGSPSRESPLSAPSDHS
uniprot
proteins
function
FUNCTION: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. {ECO:0000269|PubMed:14528312, ECO:0000269|PubMed:17543862, ECO:0000269|PubMed:19995937}.
uniprot
proteins
mass_dalton
69429
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
10718198
uniprot
proteins
pubmed
14528312
uniprot
proteins
pubmed
17543862
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19995937
uniprot
proteins
sequence_length
617
uniprot
proteins