RGS9
entrez
8787
canonical
uniprot
O75916
canonical
ensembl
ENSG00000108370
resolver
ensp
ENSP00000262406
resolver
ensp
ENSP00000396329
resolver
ensp
ENSP00000782739
resolver
genesymbol
RGS9
resolver
hgnc
HGNC:10004
resolver
uniprot
A8K1G1
resolver
uniprot
A8K3C0
resolver
uniprot
O75573
resolver
uniprot
Q696R2
resolver
uniprot
Q8TD64
resolver
uniprot
Q8TD65
resolver
uniprot
Q9HC32
resolver
uniprot
Q9HC33
resolver
uniprot_entry
A8K1G1_HUMAN
resolver
uniprot_entry
RGS9_HUMAN
resolver
uniprot_sec
A8K3C0
resolver
uniprot_sec
O75573
resolver
uniprot_sec
Q696R2
resolver
uniprot_sec
Q8TD64
resolver
uniprot_sec
Q8TD65
resolver
uniprot_sec
Q9HC32
resolver
uniprot_sec
Q9HC33
resolver
amino_acid_sequence
MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMQNQRVLVTSVPHAMTGSDVLQWIVQRLWISSLEAQNLGNFIVRYGYIYPLQDPKNLILKPDGSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYNFLNQKMNYKWDFVIMQAKEQYRAGKERNKADRYALDCQEKAYWLVHRCPPGMDNVLDYGLDRVTNPNEVKVNQKQTVVAVKKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKMDVPTGSGTCLMDSEDAGTGESGDRATEKEVICPWESL
uniprot
proteins
disease_involvement
DISEASE: Prolonged electroretinal response suppression 1 (PERRS1) [MIM:608415]: A form of bradyopsia, an ocular disorder characterized by prolonged electroretinal response suppression leading to difficulties adjusting to changes in luminance, normal to subnormal acuity and photophobia. PERRS1 is an autosomal recessive form with onset in childhood. {ECO:0000269|PubMed:14702087}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
76966
uniprot
proteins
post_translational_modification
PTM: Retinal isoform 3 is light-dependent phosphorylated at 'Ser-478'. Phosphorylation is decreased by light exposition (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
10564809
uniprot
proteins
pubmed
14614075
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14702087
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
9765512
uniprot
proteins
sequence_length
674
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 3]: Membrane; Peripheral membrane protein. Note=Isoform 3 is targeted to the membrane via its interaction with RGS9BP. {ECO:0000250}.
uniprot
proteins