Tfec
entrez
21426
canonical
uniprot
Q9WTW4
canonical
ensembl
ENSMUSG00000029553
resolver
ensp
ENSMUSP00000031533
resolver
enst
ENSMUST00000031533
resolver
genesymbol
Tfec
resolver
genesymbol_syn
Tcfec
resolver
uniprot
Q3TWR7
resolver
uniprot_entry
TFEC_MOUSE
resolver
uniprot_sec
Q3TWR7
resolver
amino_acid_sequence
MTFDCRVCDQTLKRAQPPAASCMPLAEHEPMSPDSDAGCAGNPFTNLLALGKKDGAEKWHLSGSILDVYSDEQGISSANAGLTDAPCPSILPMRKEIAETDGRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLRLRIQELEIQARAHGLPILASLGTADVGTHITKQQTHPERNLGGCCLQLTPTQGTSPEFYEQAVAFSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISPAVSKASSRSSLSSEDGDEL
uniprot
proteins
function
FUNCTION: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence) (By similarity). Binds to element F in an E-box sequence-specific manner (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form. {ECO:0000250, ECO:0000269|PubMed:11818452}.
uniprot
proteins
mass_dalton
35144
uniprot
proteins
protein_family
MiT/TFE family
uniprot
proteins
pubmed
10036191
uniprot
proteins
pubmed
11818452
uniprot
proteins
pubmed
15459106
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15908341
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
7958932
uniprot
proteins
pubmed
9973413
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
uniprot
proteins