ATP8B4
entrez
79895
canonical
uniprot
Q8TF62
canonical
ensembl
ENSG00000104043
resolver
ensp
ENSP00000284509
resolver
ensp
ENSP00000453169
resolver
ensp
ENSP00000453690
resolver
ensp
ENSP00000565186
resolver
ensp
ENSP00000565187
resolver
ensp
ENSP00000565188
resolver
ensp
ENSP00000565190
resolver
ensp
ENSP00000565191
resolver
ensp
ENSP00000636612
resolver
enst
ENST00000284509
resolver
enst
ENST00000559829
resolver
enst
ENST00000895127
resolver
enst
ENST00000895129
resolver
enst
ENST00000895131
resolver
enst
ENST00000895132
resolver
genesymbol
ATP8B4
resolver
genesymbol_syn
KIAA1939
resolver
hgnc
HGNC:13536
resolver
uniprot
Q6PG43
resolver
uniprot
Q9H727
resolver
uniprot_entry
AT8B4_HUMAN
resolver
uniprot_entry
Q6PG43_HUMAN
resolver
uniprot_sec
Q9H727
resolver
amino_acid_sequence
MFCSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGELITSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL
uniprot
proteins
ec_number
7.6.2.1
uniprot
proteins
function
FUNCTION: Component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). {ECO:0000305}.
uniprot
proteins
mass_dalton
135868
uniprot
proteins
protein_family
Cation transport ATPase (P-type) (TC 3.A.3) family
uniprot
proteins
protein_family
Type IV subfamily
uniprot
proteins
pubmed
11853319
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
20947505
uniprot
proteins
pubmed
20961850
uniprot
proteins
sequence_length
1192
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20947505}; Multi-pass membrane protein {ECO:0000269|PubMed:20947505}. Golgi apparatus {ECO:0000269|PubMed:20947505}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..66; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 73..92; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 277..298; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 328..349; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 872..892; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 905..924; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 955..976; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 991..1013; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1020..1040; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1061..1085; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins