Pwwp3a
entrez
68114
canonical
uniprot
Q6DID5
canonical
ensembl
ENSMUSG00000020156
resolver
ensp
ENSMUSP00000020365
resolver
ensp
ENSMUSP00000252603
resolver
ensp
ENSMUSP00000252613
resolver
enst
ENSMUST00000020365
resolver
genesymbol
Pwwp3a
resolver
genesymbol_syn
Mum1
resolver
uniprot
Q3TCZ4
resolver
uniprot
Q6NST9
resolver
uniprot
Q8C5E3
resolver
uniprot
Q8R1V6
resolver
uniprot
Q9R1R7
resolver
uniprot_entry
PWP3A_MOUSE
resolver
uniprot_sec
Q3TCZ4
resolver
uniprot_sec
Q6NST9
resolver
uniprot_sec
Q8C5E3
resolver
uniprot_sec
Q8R1V6
resolver
uniprot_sec
Q9R1R7
resolver
amino_acid_sequence
MTDAKYVLCRWGKRLWPAKVLARTETSAKNKKKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPIEDGITLSQKEKTDADVASQVSSAPSPSLLGEDGQAVVAQCASKRRSEYSSKSLLPSSALEDHLRCQVGPKTGLSESGAGDKSQDDSGLQLDHGQESTTKKRQRNLGEKPTRRRRSESGLSKGESVLKSQGQASSCVALASPRPPSQTRDEEPCAGVKGCDWVKSSGNIRPLSASERSRGCPTKRPRLDGGQNPPTRQLGTRTVGAAPCPRSCSGEVTMLCSAGAGDKPEEDPVSSEESTGFKSTHSLLEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPVGDSQLGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSSQCVTCMETYLEDEAQLDEVVEYLQGVCRDMDGQVPERGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR
uniprot
proteins
function
FUNCTION: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
76069
uniprot
proteins
protein_family
PWWP3A family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
682
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1. {ECO:0000250}.
uniprot
proteins