NFKBIL1
entrez
4795
canonical
uniprot
Q9UBC1
canonical
ensembl
ENSG00000204498
resolver
ensembl
ENSG00000206440
resolver
ensembl
ENSG00000227565
resolver
ensembl
ENSG00000234530
resolver
ensembl
ENSG00000235125
resolver
ensembl
ENSG00000236196
resolver
ensembl
ENSG00000236346
resolver
ensp
ENSP00000365315
resolver
ensp
ENSP00000365316
resolver
ensp
ENSP00000365318
resolver
ensp
ENSP00000372992
resolver
ensp
ENSP00000383137
resolver
ensp
ENSP00000383142
resolver
ensp
ENSP00000394486
resolver
ensp
ENSP00000395544
resolver
ensp
ENSP00000395977
resolver
ensp
ENSP00000396656
resolver
ensp
ENSP00000399871
resolver
ensp
ENSP00000401830
resolver
ensp
ENSP00000404901
resolver
ensp
ENSP00000407809
resolver
ensp
ENSP00000408426
resolver
ensp
ENSP00000411174
resolver
ensp
ENSP00000411611
resolver
ensp
ENSP00000413643
resolver
ensp
ENSP00000413952
resolver
ensp
ENSP00000414084
resolver
ensp
ENSP00000414206
resolver
enst
ENST00000376145
resolver
enst
ENST00000376146
resolver
enst
ENST00000383500
resolver
enst
ENST00000400279
resolver
enst
ENST00000400285
resolver
enst
ENST00000414391
resolver
enst
ENST00000419122
resolver
enst
ENST00000419623
resolver
enst
ENST00000421396
resolver
enst
ENST00000424652
resolver
enst
ENST00000428467
resolver
enst
ENST00000430501
resolver
enst
ENST00000430961
resolver
enst
ENST00000432160
resolver
enst
ENST00000434332
resolver
enst
ENST00000442947
resolver
enst
ENST00000451911
resolver
enst
ENST00000453377
resolver
enst
ENST00000455376
resolver
enst
ENST00000456607
resolver
genesymbol
NFKBIL1
resolver
genesymbol_syn
IKBL
resolver
hgnc
HGNC:7800
resolver
uniprot
A0A0A0MRT5
resolver
uniprot
A6NL91
resolver
uniprot
A8K778
resolver
uniprot
B4DUW1
resolver
uniprot
Q14625
resolver
uniprot
Q5HYU4
resolver
uniprot
Q5RJ72
resolver
uniprot
Q5ST96
resolver
uniprot
Q5STV4
resolver
uniprot
Q5STV5
resolver
uniprot
Q5STV6
resolver
uniprot
Q9UBX4
resolver
uniprot_entry
A0A0A0MRT5_HUMAN
resolver
uniprot_entry
A8K778_HUMAN
resolver
uniprot_entry
IKBL1_HUMAN
resolver
uniprot_entry
Q5STV6_HUMAN
resolver
uniprot_sec
A6NL91
resolver
uniprot_sec
B4DUW1
resolver
uniprot_sec
Q14625
resolver
uniprot_sec
Q5HYU4
resolver
uniprot_sec
Q5RJ72
resolver
uniprot_sec
Q5ST96
resolver
uniprot_sec
Q5STV4
resolver
uniprot_sec
Q5STV5
resolver
uniprot_sec
Q9UBX4
resolver
amino_acid_sequence
MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
uniprot
proteins
disease_involvement
DISEASE: Rheumatoid arthritis (RA) [MIM:180300]: An inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. {ECO:0000305|PubMed:12509789}. Note=Disease susceptibility is associated with variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. {ECO:0000269|PubMed:20829348}.
uniprot
proteins
mass_dalton
43257
uniprot
proteins
pubmed
10202016
uniprot
proteins
pubmed
10369924
uniprot
proteins
pubmed
12509789
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
20829348
uniprot
proteins
pubmed
8081366
uniprot
proteins
pubmed
9480751
uniprot
proteins
sequence_length
381
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20829348}. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus.
uniprot
proteins