TRAT1
entrez
50852
canonical
uniprot
Q6PIZ9
canonical
ensembl
ENSG00000163519
resolver
ensp
ENSP00000295756
resolver
ensp
ENSP00000410097
resolver
enst
ENST00000295756
resolver
enst
ENST00000426646
resolver
genesymbol
TRAT1
resolver
genesymbol_syn
TCRIM
resolver
hgnc
HGNC:30698
resolver
uniprot
C9JF66
resolver
uniprot
Q9NZX5
resolver
uniprot_entry
C9JF66_HUMAN
resolver
uniprot_entry
TRAT1_HUMAN
resolver
uniprot_sec
Q9NZX5
resolver
amino_acid_sequence
MSGISGCPFFLWGLLALLGLALVISLIFNISHYVEKQRQDKMYSYSSDHTRVDEYYIEDTPIYGNLDDMISEPMDENCYEQMKARPEKSVNKMQEATPSAQATNETQMCYASLDHSVKGKRRKPRKQNTHFSDKDGDEQLHAIDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGLIRAKREPIN
uniprot
proteins
function
FUNCTION: Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. {ECO:0000269|PubMed:11390434}.
uniprot
proteins
mass_dalton
21211
uniprot
proteins
mutagenesis
MUTAGEN 79; /note="Y->F: Abolishes interaction with PIK3R1."; /evidence="ECO:0000269|PubMed:9687533
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosines by LCK or FYN upon TCR activation. {ECO:0000269|PubMed:9687533}.
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
11390434
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16160011
uniprot
proteins
pubmed
9687533
uniprot
proteins
sequence_length
186
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:9687533}; Single-pass type III membrane protein {ECO:0000269|PubMed:9687533}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins