Snx33
entrez
235406
canonical
uniprot
Q4VAA7
canonical
ensembl
ENSMUSG00000032733
resolver
ensp
ENSMUSP00000060225
resolver
enst
ENSMUST00000050916
resolver
genesymbol
Snx33
resolver
genesymbol_syn
Sh3px3
resolver
uniprot
Q8BPM5
resolver
uniprot
Q8C832
resolver
uniprot_entry
SNX33_MOUSE
resolver
uniprot_sec
Q8BPM5
resolver
uniprot_sec
Q8C832
resolver
amino_acid_sequence
MALKGRALYDFHSENKEEISIQQDEELVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRPGISTNHVDYSNSPAGSLGTQGSLYSSPSMASPARSGGGSGFLSNPGSFEDDDDDDWDDWDDGCTVVEEPLAGGLGTNGHPPLNLSYPGAYPNQHMAFRPKAPLERQDSLASAKRGSVVGRNLNRFSCFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSIEDPTKQTKFKGIKSYISYKLTPTHAGSPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSNVAAELVRKHVGGFRKEFQKLGSAFQAISHAFQMDPPFRSDALNNAISHTGRTYETVGEMFAEQPKHDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMAQEEADGIRRRCRVVGFALQAEMNHFHQRRELDFKHMMQSYLRQQILFYQRVGQQLEKTLHMYDHL
uniprot
proteins
function
FUNCTION: Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
65315
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250}.
uniprot
proteins
protein_family
Sorting nexin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18353773
uniprot
proteins
pubmed
26567222
uniprot
proteins
sequence_length
574
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Primarily detected in the cytosol. A minor proportion is membrane-bound (By similarity). {ECO:0000250}.
uniprot
proteins