LYL1
entrez
4066
canonical
uniprot
P12980
canonical
ensembl
ENSG00000104903
resolver
ensp
ENSP00000264824
resolver
ensp
ENSP00000562230
resolver
ensp
ENSP00000562231
resolver
ensp
ENSP00000562232
resolver
enst
ENST00000264824
resolver
enst
ENST00000892171
resolver
enst
ENST00000892172
resolver
enst
ENST00000892173
resolver
genesymbol
LYL1
resolver
genesymbol_syn
BHLHA18
resolver
hgnc
HGNC:6734
resolver
uniprot
O76102
resolver
uniprot_entry
LYL1_HUMAN
resolver
uniprot_sec
O76102
resolver
amino_acid_sequence
MCPPQAQAEVGPTMTEKAEMVCAPSPAPAPPPKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGVAMPTTELGTLRPPLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSSRLKRRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARSQPAPPADPDGSPGGAARPIKMEQTALSPEVR
uniprot
proteins
disease_involvement
DISEASE: Note=A chromosomal aberration involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;19)(q35;p13) with TCRB. {ECO:0000269|PubMed:2752424}.
uniprot
proteins
function
FUNCTION: Transcriptional coactivator that interacts with CREB1 and activates several CREB1-responsive genes. {ECO:0000269|PubMed:18160048}.
uniprot
proteins
mass_dalton
29938
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18160048
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
2752424
uniprot
proteins
sequence_length
280
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
uniprot
proteins