Sfxn3
entrez
94280
canonical
uniprot
Q91V61
canonical
ensembl
ENSMUSG00000025212
resolver
ensp
ENSMUSP00000059419
resolver
ensp
ENSMUSP00000081537
resolver
ensp
ENSMUSP00000107585
resolver
ensp
ENSMUSP00000264013
resolver
ensp
ENSMUSP00000264027
resolver
enst
ENSMUST00000084493
resolver
genesymbol
Sfxn3
resolver
uniprot
F7C4G5
resolver
uniprot
Q3U4F0
resolver
uniprot
Q544M7
resolver
uniprot
Q8C1Z2
resolver
uniprot_entry
F7C4G5_MOUSE
resolver
uniprot_entry
Q3U4F0_MOUSE
resolver
uniprot_entry
SFXN3_MOUSE
resolver
uniprot_sec
Q544M7
resolver
uniprot_sec
Q8C1Z2
resolver
amino_acid_sequence
MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGEQLEASRNIVQNYRAGVATPGLTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLTKHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVISRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQNPSIDVVYYNKGL
uniprot
proteins
function
FUNCTION: Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. {ECO:0000250|UniProtKB:Q9BWM7}.
uniprot
proteins
mass_dalton
35406
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
11274051
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
321
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:Q9BWM7}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 146..164; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins