DDA1
entrez
79016
canonical
uniprot
Q9BW61
canonical
ensembl
ENSG00000130311
resolver
ensp
ENSP00000352928
resolver
ensp
ENSP00000472171
resolver
ensp
ENSP00000473086
resolver
enst
ENST00000359866
resolver
enst
ENST00000593466
resolver
enst
ENST00000596582
resolver
genesymbol
DDA1
resolver
genesymbol_syn
C19orf58
resolver
genesymbol_syn
PCIA1
resolver
hgnc
HGNC:28360
resolver
uniprot_entry
DDA1_HUMAN
resolver
amino_acid_sequence
MADFLKGLPVYNKSNFSRFHADSVCKASNRRPSVYLPTREYPSEQIIVTEKTNILLRYLHQQWDKKNAAKKRDQEQVELEGESSAPPRKVARTDSPDMHEDT
uniprot
proteins
function
FUNCTION: Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:17452440, PubMed:28302793, PubMed:28437394, PubMed:31686031, PubMed:31819272). In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex (PubMed:31686031, PubMed:31819272). {ECO:0000269|PubMed:17452440, ECO:0000269|PubMed:28302793, ECO:0000269|PubMed:28437394, ECO:0000269|PubMed:31686031, ECO:0000269|PubMed:31819272}.
uniprot
proteins
mass_dalton
11835
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:17452440, ECO:0000269|PubMed:28302793}.
uniprot
proteins
protein_family
DDA1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17452440
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28302793
uniprot
proteins
pubmed
28437394
uniprot
proteins
pubmed
28546157
uniprot
proteins
pubmed
30564455
uniprot
proteins
pubmed
31686031
uniprot
proteins
pubmed
31693891
uniprot
proteins
pubmed
31693911
uniprot
proteins
pubmed
31819272
uniprot
proteins
sequence_length
102
uniprot
proteins