Lhfpl4
entrez
269788
canonical
uniprot
Q5U4E0
canonical
ensembl
ENSMUSG00000042873
resolver
ensp
ENSMUSP00000124470
resolver
enst
ENSMUST00000162280
resolver
genesymbol
Lhfpl4
resolver
genesymbol_syn
Garlh4
resolver
genesymbol_syn
Kiaa4027
resolver
genesymbol_syn
Lh4
resolver
uniprot
Q5DTS1
resolver
uniprot
Q8BQU2
resolver
uniprot_entry
LHPL4_MOUSE
resolver
uniprot_sec
Q5DTS1
resolver
uniprot_sec
Q8BQU2
resolver
amino_acid_sequence
MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFALFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKQENKDFVGTTVSSVLRPGGDVSGWGVLPCPVAHTQGP
uniprot
proteins
function
FUNCTION: Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites (PubMed:28279354, PubMed:28978485, PubMed:29742426). Acts in concert with NLGN2 to recruit or stabilize GABAARs (PubMed:29742426). {ECO:0000269|PubMed:28279354, ECO:0000269|PubMed:28978485, ECO:0000269|PubMed:29742426}.
uniprot
proteins
mass_dalton
27050
uniprot
proteins
protein_family
LHFP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26964900
uniprot
proteins
pubmed
28279354
uniprot
proteins
pubmed
28978485
uniprot
proteins
pubmed
29742426
uniprot
proteins
sequence_length
247
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, dendrite {ECO:0000250|UniProtKB:Q7TSY2}. Postsynaptic cell membrane {ECO:0000269|PubMed:28978485, ECO:0000269|PubMed:29742426}; Multi-pass membrane protein {ECO:0000255}. Note=Specifically localizes to inhibitory postsynaptic sites (PubMed:28978485, PubMed:29742426). Colocalizes with GPHN, GABRG2 and NLGN2 at inhibitory postsynaptic sites (By similarity) (PubMed:29742426). {ECO:0000250|UniProtKB:Q7TSY2, ECO:0000269|PubMed:28978485, ECO:0000269|PubMed:29742426}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 97..117; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 127..147; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 178..198; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins