DEUP1
entrez
159989
canonical
uniprot
Q05D60
canonical
ensembl
ENSG00000165325
resolver
ensp
ENSP00000298050
resolver
ensp
ENSP00000433537
resolver
ensp
ENSP00000434635
resolver
ensp
ENSP00000435079
resolver
ensp
ENSP00000479457
resolver
enst
ENST00000525646
resolver
genesymbol
DEUP1
resolver
genesymbol_syn
CCDC67
resolver
hgnc
HGNC:26344
resolver
uniprot
E9PJR5
resolver
uniprot
E9PLX9
resolver
uniprot
Q8NEF1
resolver
uniprot
Q96LL7
resolver
uniprot_entry
DEUP1_HUMAN
resolver
uniprot_entry
E9PLX9_HUMAN
resolver
uniprot_sec
E9PJR5
resolver
uniprot_sec
Q8NEF1
resolver
uniprot_sec
Q96LL7
resolver
amino_acid_sequence
MENQAHNTMGTSPCEAELQELMEQIDIMVSNKKMDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLAMTQNYEGQLQSLKAQFSKLTNNFEKLRLHQMKQNKVPRKELPHLKEEIPFELSNLNQKLEEFRAKSREWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRLICDPDPNCEINERDEFIIEKLKSAVNEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLQLHRELLKIGECQNAQGNKTRLESSYLPSIKEPERKIKELFSVMQDQPNHEKELNKIRSQLQQVEEYHNSEQERMRNEISDLTEELHQKEITIATVTKKAALLEKQLKMELEIKEKMLAKQKVSDMKYKAVRTENTHLKGMMGDLDPGEYMSMDFTNREQSRHTSINKLQYENERLRNDLAKLHVNGKSTWTNQNTYEETGRYAYQSQIKVEQNEERLSHDCEPNRSTMPPLPPSTFQAKEMTSPLVSDDDVFPLSPPDMSFPASLAAQHFLLEEEKRAKELEKLLNTHIDELQRHTEFTLNKYSKLKQNRHI
uniprot
proteins
function
FUNCTION: Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
70977
uniprot
proteins
protein_family
CEP63 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
sequence_length
604
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes to the deuterosome. {ECO:0000250}.
uniprot
proteins