GULP1
entrez
51454
canonical
uniprot
Q9UBP9
canonical
ensembl
ENSG00000144366
resolver
ensp
ENSP00000352047
resolver
ensp
ENSP00000386289
resolver
ensp
ENSP00000386732
resolver
ensp
ENSP00000387144
resolver
ensp
ENSP00000387171
resolver
ensp
ENSP00000391712
resolver
ensp
ENSP00000514747
resolver
ensp
ENSP00000578963
resolver
ensp
ENSP00000578964
resolver
ensp
ENSP00000578965
resolver
ensp
ENSP00000578967
resolver
ensp
ENSP00000578969
resolver
ensp
ENSP00000578973
resolver
ensp
ENSP00000578976
resolver
ensp
ENSP00000578977
resolver
ensp
ENSP00000578979
resolver
ensp
ENSP00000578980
resolver
ensp
ENSP00000590045
resolver
ensp
ENSP00000590048
resolver
ensp
ENSP00000590052
resolver
ensp
ENSP00000590053
resolver
ensp
ENSP00000590054
resolver
ensp
ENSP00000590061
resolver
ensp
ENSP00000590065
resolver
ensp
ENSP00000590068
resolver
ensp
ENSP00000590079
resolver
ensp
ENSP00000633806
resolver
ensp
ENSP00000633809
resolver
ensp
ENSP00000633812
resolver
ensp
ENSP00000633815
resolver
ensp
ENSP00000633817
resolver
ensp
ENSP00000633818
resolver
ensp
ENSP00000633822
resolver
ensp
ENSP00000633827
resolver
enst
ENST00000433052
resolver
enst
ENST00000699997
resolver
enst
ENST00000908908
resolver
enst
ENST00000908914
resolver
enst
ENST00000908921
resolver
enst
ENST00000919994
resolver
enst
ENST00000919995
resolver
enst
ENST00000920002
resolver
enst
ENST00000920020
resolver
enst
ENST00000963747
resolver
enst
ENST00000963750
resolver
enst
ENST00000963753
resolver
enst
ENST00000963756
resolver
enst
ENST00000963758
resolver
enst
ENST00000963763
resolver
genesymbol
GULP1
resolver
genesymbol_syn
CED6
resolver
genesymbol_syn
GULP
resolver
hgnc
HGNC:18649
resolver
uniprot
A0A8V8TQW5
resolver
uniprot
B2RB51
resolver
uniprot
B4DQ40
resolver
uniprot
B8ZZ72
resolver
uniprot
D3DPH1
resolver
uniprot
E9PB86
resolver
uniprot
H7BZV7
resolver
uniprot
Q53PC1
resolver
uniprot
Q53RF3
resolver
uniprot
Q9BVL3
resolver
uniprot_entry
A0A8V8TQW5_HUMAN
resolver
uniprot_entry
GULP1_HUMAN
resolver
uniprot_entry
H7BZV7_HUMAN
resolver
uniprot_sec
B2RB51
resolver
uniprot_sec
B4DQ40
resolver
uniprot_sec
B8ZZ72
resolver
uniprot_sec
D3DPH1
resolver
uniprot_sec
E9PB86
resolver
uniprot_sec
Q53PC1
resolver
uniprot_sec
Q53RF3
resolver
uniprot_sec
Q9BVL3
resolver
amino_acid_sequence
MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC
uniprot
proteins
function
FUNCTION: May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. {ECO:0000269|PubMed:10574763, ECO:0000269|PubMed:10574771, ECO:0000269|PubMed:16497666, ECO:0000269|PubMed:17398097}.
uniprot
proteins
mass_dalton
34490
uniprot
proteins
mutagenesis
MUTAGEN 176; /note="L->P: Loss of dimerization; when associated with P-183."; /evidence="ECO:0000269|PubMed:10734103"; MUTAGEN 183; /note="L->P: Loss of dimerization; when associated with P-176."; /evidence="ECO:0000269|PubMed:10734103
uniprot
proteins
protein_family
Ced-6 family
uniprot
proteins
pubmed
10574763
uniprot
proteins
pubmed
10574771
uniprot
proteins
pubmed
10734103
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16497666
uniprot
proteins
pubmed
17205124
uniprot
proteins
pubmed
17398097
uniprot
proteins
pubmed
17643423
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18230608
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
304
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16497666}. Note=May associate with the cytoplasmic side of the plasma membrane and early endosomes.
uniprot
proteins