Rida
entrez
65151
canonical
uniprot
P52759
canonical
genesymbol
Rida
resolver
genesymbol_syn
Psp1
resolver
uniprot
O35262
resolver
uniprot
Q9WUV8
resolver
uniprot_entry
RIDA_RAT
resolver
uniprot_sec
O35262
resolver
uniprot_sec
Q9WUV8
resolver
amino_acid_sequence
MSSIIRKVISTSKAPAAIGAYSQAVLVDRTIYVSGQIGMDPSSGQLVPGGVAEEAKQALKNLGEILKAAGCDFTNVVKTTVLLADINDFGTVNEIYKTYFQGNLPARAAYQVAALPKGSRIEIEAIAVQGPFTTAGL
uniprot
proteins
ec_number
3.5.99.10
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase. {ECO:0000250|UniProtKB:P52758}.; FUNCTION: Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex (PubMed:10400702). Acts by bridging YTHDF2 and the ribonuclease P/MRP complex (By similarity). RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage (By similarity). {ECO:0000250|UniProtKB:P52758, ECO:0000269|PubMed:10400702}.
uniprot
proteins
mass_dalton
14303
uniprot
proteins
protein_family
RutC family
uniprot
proteins
pubmed
10400702
uniprot
proteins
pubmed
11003673
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17416349
uniprot
proteins
pubmed
8385007
uniprot
proteins
pubmed
8530410
uniprot
proteins
sequence_length
137
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P52758}. Nucleus {ECO:0000250|UniProtKB:P52758}. Peroxisome {ECO:0000269|PubMed:11003673}. Mitochondrion {ECO:0000269|PubMed:17416349}. Note=Mostly cytoplasmic but, in less differentiated cells occasionally nuclear. {ECO:0000250|UniProtKB:P52758}.
uniprot
proteins