ATAD2
entrez
29028
canonical
uniprot
Q6PL18
canonical
ensembl
ENSG00000156802
resolver
ensp
ENSP00000287394
resolver
ensp
ENSP00000429213
resolver
ensp
ENSP00000754406
resolver
genesymbol
ATAD2
resolver
hgnc
HGNC:30123
resolver
uniprot
Q14CR1
resolver
uniprot
Q658P2
resolver
uniprot
Q68CQ0
resolver
uniprot
Q6PJV6
resolver
uniprot
Q8N890
resolver
uniprot
Q9UHS5
resolver
uniprot_entry
ATAD2_HUMAN
resolver
uniprot_sec
Q14CR1
resolver
uniprot_sec
Q658P2
resolver
uniprot_sec
Q68CQ0
resolver
uniprot_sec
Q6PJV6
resolver
uniprot_sec
Q8N890
resolver
uniprot_sec
Q9UHS5
resolver
amino_acid_sequence
MVVLRSSLELHNHSAASATGSLDLSSDFLSLEHIGRRRLRSAGAAQKKPAATTAKAGDGSSVKEVETYHRTRALRSLRKDAQNSSDSSFEKNVEITEQLANGRHFTRQLARQQADKKKEEHREDKVIPVTRSLRARNIVQSTEHLHEDNGDVEVRRSCRIRSRYSGVNQSMLFDKLITNTAEAVLQKMDDMKKMRRQRMRELEDLGVFNETEESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQKRYYLRQRKATVYYQAPLEKPRHQRKPNIFYSGPASPARPRYRLSSAGPRSPYCKRMNRRRHAIHSSDSTSSSSSEDEQHFERRRKRSRNRAINRCLPLNFRKDELKGIYKDRMKIGASLADVDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMIPASQRAVTSPGQALSTVVKPLLQNTVDKILEALQRVFPHAEFRTNKTLDSDISCPLLESDLAYSDDDVPSVYENGLSQKSSHKAKDNFNFLHLNRNACYQPMSFRPRILIVGEPGFGQGSHLAPAVIHALEKFTVYTLDIPVLFGVSTTSPEETCAQVIREAKRTAPSIVYVPHIHVWWEIVGPTLKATFTTLLQNIPSFAPVLLLATSDKPHSALPEEVQELFIRDYGEIFNVQLPDKEERTKFFEDLILKQAAKPPISKKKAVLQALEVLPVAPPPEPRSLTAEEVKRLEEQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESRKKRGCSSSKYAPSYYHVMPKQNSTLVGDKRSDPEQNEKLKTPSTPVACSTPAQLKRKIRKKSNWYLGTIKKRRKISQAKDDSQNAIDHKIESDTEETQDTSVDHNETGNTGESSVEENEKQQNASESKLELRNNSNTCNIENELEDSRKTTACTELRDKIACNGDASSSQIIHISDENEGKEMCVLRMTRARRSQVEQQQLITVEKALAILSQPTPSLVVDHERLKNLLKTVVKKSQNYNIFQLENLYAVISQCIYRHRKDHDKTSLIQKMEQEVENFSCSR
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
function
FUNCTION: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. {ECO:0000269|PubMed:17998543}.
uniprot
proteins
mass_dalton
158554
uniprot
proteins
mutagenesis
MUTAGEN 473; /note="K->T: Reduces the ability to mediate estradiol-dependent induction of CCND1 and E2F1; when associated with Q-532."; /evidence="ECO:0000269|PubMed:17998543"; MUTAGEN 532; /note="E->Q: Reduces the ability to mediate estradiol-dependent induction of CCND1 and E2F1; when associated with T-473."; /evidence="ECO:0000269|PubMed:17998543
uniprot
proteins
protein_family
AAA ATPase family
uniprot
proteins
pubmed
11483580
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15334068
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15721472
uniprot
proteins
pubmed
16709241
uniprot
proteins
pubmed
17076897
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17660802
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
17998543
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22464331
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25593309
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
1390
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17998543, ECO:0000269|PubMed:25593309}.
uniprot
proteins