CHAMP1
entrez
283489
canonical
uniprot
Q96JM3
canonical
ensembl
ENSG00000198824
resolver
ensp
ENSP00000354730
resolver
ensp
ENSP00000494031
resolver
ensp
ENSP00000495985
resolver
ensp
ENSP00000496699
resolver
ensp
ENSP00000515032
resolver
ensp
ENSP00000515033
resolver
ensp
ENSP00000601641
resolver
enst
ENST00000361283
resolver
enst
ENST00000643483
resolver
enst
ENST00000644294
resolver
enst
ENST00000645174
resolver
enst
ENST00000700527
resolver
enst
ENST00000700528
resolver
enst
ENST00000931582
resolver
genesymbol
CHAMP1
resolver
genesymbol_syn
C13orf8
resolver
genesymbol_syn
CAMP
resolver
genesymbol_syn
CHAMP
resolver
genesymbol_syn
KIAA1802
resolver
genesymbol_syn
ZNF828
resolver
hgnc
HGNC:20311
resolver
uniprot
B3KU06
resolver
uniprot
Q6P181
resolver
uniprot
Q8NC88
resolver
uniprot
Q9BST0
resolver
uniprot_entry
CHAP1_HUMAN
resolver
uniprot_sec
B3KU06
resolver
uniprot_sec
Q6P181
resolver
uniprot_sec
Q8NC88
resolver
uniprot_sec
Q9BST0
resolver
amino_acid_sequence
MEAFQELRKPSARLECDHCSFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAKLFHCHKCFFTSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEANKKLMEALEPPLEEQQI
uniprot
proteins
function
FUNCTION: Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore. {ECO:0000269|PubMed:21063390}.
uniprot
proteins
mass_dalton
89099
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by CDK1. Mitotic phosphorylation is required for the attachment of spindle microtubules to the kinetochore. {ECO:0000269|PubMed:21063390}.
uniprot
proteins
pubmed
11347906
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20850016
uniprot
proteins
pubmed
21063390
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25533962
uniprot
proteins
pubmed
25772364
uniprot
proteins
pubmed
26340335
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
812
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21063390}. Chromosome {ECO:0000269|PubMed:21063390}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:21063390}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:21063390}.
uniprot
proteins