LCMT2
entrez
9836
canonical
uniprot
O60294
canonical
ensembl
ENSG00000168806
resolver
ensp
ENSP00000307214
resolver
enst
ENST00000305641
resolver
genesymbol
LCMT2
resolver
genesymbol_syn
KIAA0547
resolver
genesymbol_syn
TYW4
resolver
hgnc
HGNC:17558
resolver
uniprot
Q4JFT6
resolver
uniprot
Q96B55
resolver
uniprot
Q9NR10
resolver
uniprot_entry
TYW4_HUMAN
resolver
uniprot_sec
Q4JFT6
resolver
uniprot_sec
Q96B55
resolver
uniprot_sec
Q9NR10
resolver
amino_acid_sequence
MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVARRKAERIGETPELCALTGPFERGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGHASVFLSPDVILSAGGFGEQEGRHCRVSQFHLLSRDCDSEWKGSQIGSCGTGVQWDGRLYHTMTRLSESRVLVLGGRLSPVSPALGVLQLHFFKSEDNNTEDLKVTITKAGRKDDSTLCCWRHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSACTWQGGALIAGGLGASEEPLNSVLFLRPISCGFLWESVDIQPPITPRYSHTAHVLNGKLLLVGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWPLMLHNHTSILLPEEQQLLLLGGGGNCFSFGTYFNPHTVTLDLSSLSAGQ
uniprot
proteins
ec_number
2.1.1.290
uniprot
proteins
ec_number
2.3.1.231
uniprot
proteins
function
FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway (Probable). Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (Probable). {ECO:0000305|PubMed:39523586}.
uniprot
proteins
mass_dalton
75602
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
uniprot
proteins
protein_family
LCMT family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
12853982
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
39523586
uniprot
proteins
pubmed
9628581
uniprot
proteins
sequence_length
686
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q08282}.
uniprot
proteins