Rgp1
entrez
242406
canonical
uniprot
Q8BHT7
canonical
ensembl
ENSMUSG00000028468
resolver
ensp
ENSMUSP00000030190
resolver
ensp
ENSMUSP00000103518
resolver
enst
ENSMUST00000030190
resolver
enst
ENSMUST00000107886
resolver
genesymbol
Rgp1
resolver
genesymbol_syn
Kiaa0258
resolver
uniprot
B1AWI4
resolver
uniprot
Q6ZQF1
resolver
uniprot_entry
RGP1_MOUSE
resolver
uniprot_sec
B1AWI4
resolver
uniprot_sec
Q6ZQF1
resolver
amino_acid_sequence
MIEVVAELSRGPVFLAGEALECVVTVTNPLPPTATSASSEALAWASAQIHCQFHASESRVALPPPDSSQPDVQPDSQTVFLPHRGERGQCILSTPPKILFCDLRLDPGESKSYSYSEVLPTEGPPSFRGQSVKYVYKLTIGCQRVNSPITLLRVPLRVLVLTGLQDVHFPQDEAVAPSSPFLEEDDSGKKDSWLAELAGERLMAATSCRSLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGTLNLGEGTVACLQFSVSLQTEERVQPEYQRRRGTGVAPSVSHVTHARHQESCLHTTRTSFSLPIPLCSTPGFCTAIVSLKWRLHFEFVTSREPGLVLLPPLEQPEPATWTGPEQVPVDTFSWDLPIKVLPTSPTLVSYAAPGPSTSSITI
uniprot
proteins
function
FUNCTION: The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. {ECO:0000250|UniProtKB:Q92546}.
uniprot
proteins
mass_dalton
42498
uniprot
proteins
protein_family
RGP1 family
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
391
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q92546}. Membrane {ECO:0000250|UniProtKB:Q92546}.
uniprot
proteins