Lingo1
entrez
235402
canonical
uniprot
Q9D1T0
canonical
ensembl
ENSMUSG00000049556
resolver
ensp
ENSMUSP00000059050
resolver
ensp
ENSMUSP00000109885
resolver
ensp
ENSMUSP00000109894
resolver
ensp
ENSMUSP00000148179
resolver
enst
ENSMUST00000053568
resolver
enst
ENSMUST00000114247
resolver
enst
ENSMUST00000114256
resolver
enst
ENSMUST00000210032
resolver
genesymbol
Lingo1
resolver
genesymbol_syn
Lern1
resolver
genesymbol_syn
Lrrn6a
resolver
uniprot
A9DA50
resolver
uniprot
F6WTK6
resolver
uniprot
Q3TQJ4
resolver
uniprot
Q6VVF9
resolver
uniprot
Q7TT38
resolver
uniprot_entry
A9DA50_MOUSE
resolver
uniprot_entry
F6WTK6_MOUSE
resolver
uniprot_entry
LIGO1_MOUSE
resolver
uniprot_sec
Q3TQJ4
resolver
uniprot_sec
Q6VVF9
resolver
uniprot_sec
Q7TT38
resolver
amino_acid_sequence
MLAGGMRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIGTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESAFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFTCRRAHIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPRKSDAGISSADAPRKFNMKMI
uniprot
proteins
function
FUNCTION: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. {ECO:0000250|UniProtKB:Q96FE5, ECO:0000269|PubMed:20093372, ECO:0000305|PubMed:22923615}.
uniprot
proteins
mass_dalton
69101
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. Contains predominantly high-mannose glycans (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
14686891
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17726113
uniprot
proteins
pubmed
18186492
uniprot
proteins
pubmed
20093372
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22923615
uniprot
proteins
sequence_length
614
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:18186492}; Single-pass type I membrane protein {ECO:0000269|PubMed:18186492}.
uniprot
proteins
transmembrane_region
TRANSMEM 556..576; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins