GATD1
entrez
347862
canonical
uniprot
Q8NB37
canonical
ensembl
ENSG00000177225
resolver
ensp
ENSP00000321691
resolver
ensp
ENSP00000431183
resolver
ensp
ENSP00000433322
resolver
ensp
ENSP00000670397
resolver
enst
ENST00000526325
resolver
genesymbol
GATD1
resolver
genesymbol
PDDC1
resolver
genesymbol_syn
FERRY5
resolver
genesymbol_syn
PDDC1
resolver
hgnc
HGNC:26616
resolver
uniprot
B7Z1J9
resolver
uniprot
B7ZKW3
resolver
uniprot
B7ZKW4
resolver
uniprot
B7ZKW5
resolver
uniprot
E9PLI5
resolver
uniprot
Q2NL76
resolver
uniprot
Q6ZQY0
resolver
uniprot
Q8NAE0
resolver
uniprot_entry
B7Z1J9_HUMAN
resolver
uniprot_entry
B7ZKW3_HUMAN
resolver
uniprot_entry
B7ZKW4_HUMAN
resolver
uniprot_entry
E9PLI5_HUMAN
resolver
uniprot_entry
GALD1_HUMAN
resolver
uniprot_sec
B7ZKW5
resolver
uniprot_sec
Q2NL76
resolver
uniprot_sec
Q6ZQY0
resolver
uniprot_sec
Q8NAE0
resolver
amino_acid_sequence
MASERLPNRPACLLVASGAAEGVSAQSFLHCFTMASTAFNLQVATPGGKAMEFVDVTESNARWVQDFRLKAYASPAKLESIDGARYHALLIPSCPGALTDLASSGSLARILQHFHSESKPICAVGHGVAALCCATNEDRSWVFDSYSLTGPSVCELVRAPGFARLPLVVEDFVKDSGACFSASEPDAVHVVLDRHLVTGQNASSTVPAVQNLLFLCGSRK
uniprot
proteins
function
FUNCTION: Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary) (PubMed:37267905, PubMed:37267906). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (PubMed:37267905). {ECO:0000269|PubMed:37267905, ECO:0000269|PubMed:37267906}.
uniprot
proteins
mass_dalton
23298
uniprot
proteins
mutagenesis
MUTAGEN 166; /note="P->S: Does not affect FERRY complex assembly. Does not affect FERRY complex binding to mRNA."; /evidence="ECO:0000269|PubMed:37267906
uniprot
proteins
protein_family
Peptidase C56 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
37267905
uniprot
proteins
pubmed
37267906
uniprot
proteins
sequence_length
220
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}. Early endosome {ECO:0000305|PubMed:37267905}.
uniprot
proteins