Panx2
entrez
362979
canonical
uniprot
P60571
canonical
ensembl
ENSRNOG00000055530
resolver
ensembl
ENSRNOG00055011733
resolver
ensembl
ENSRNOG00060022721
resolver
ensembl
ENSRNOG00065016683
resolver
ensp
ENSRNOP00000069647
resolver
ensp
ENSRNOP00000085314
resolver
ensp
ENSRNOP00055016075
resolver
ensp
ENSRNOP00060032684
resolver
ensp
ENSRNOP00065021929
resolver
enst
ENSRNOT00000111032
resolver
enst
ENSRNOT00055019951
resolver
enst
ENSRNOT00060039498
resolver
enst
ENSRNOT00065027809
resolver
genesymbol
Panx2
resolver
genesymbol_syn
Panx
resolver
genesymbol_syn
Px2
resolver
uniprot
A0A8I6A329
resolver
uniprot_entry
A0A8I6A329_RAT
resolver
uniprot_entry
PANX2_RAT
resolver
amino_acid_sequence
MHHLLEQSADMATALLAGEKLRELILPGSQDDKAGALAALLLQLKLELPFDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQALYARGYCWTELRDALPGVDASLWPSLFEHKFLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKREIIENAEKEKSPEQNLFEKYLERRGRSNFLAKLYLARHVLILLLSVVPISYLCTYYATQKQNEFTCALGASPDGPVGSAGPTVRVSCKLPSVQLQRIIAGVDIVLLCFMNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDTTPTVRDSGIQTVDPSINPAEPEGSAEPPVVKRPRKKMKWIPTSNPLPQPFKEQLAIMRVENSKTEKPKPVRRKTATDTLIAPLLDAGARAAHHYKGSGGDTGPSSAPPAASEKKHTRHFSLDVHPYILGSKKAKTEAVPPALPASRSQEGGFLSQTEECGLGLAAAPTKDAPLPEKEIPYPTESALPSGGPFHVCSPPTASAAASLSPSSLGKADPLTILSRNATHPLLHISTLYEAREEEEGGPCAPSDMGDLLSIPPPQQILIATFEEPRTVVSTVEF
uniprot
proteins
function
FUNCTION: Structural component of the gap junctions and the hemichannels.
uniprot
proteins
mass_dalton
74434
uniprot
proteins
post_translational_modification
PTM: S-palmitoylated in neural stem and progenitor cells. {ECO:0000250|UniProtKB:Q6IMP4}.; PTM: Cleaved by CASP3 and CASP7 during apoptosis. Cleavage has no effect on it function. {ECO:0000250|UniProtKB:Q6IMP4}.
uniprot
proteins
protein_family
Pannexin family
uniprot
proteins
pubmed
14597722
uniprot
proteins
sequence_length
674
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q6IMP4}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q6IMP4}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q6IMP4}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Note=Localizes to Golgi apparatus and endoplasmic reticulum in multipotential neural stem and progenitor cells and to plasma membrane in terminally differentiated neurons. {ECO:0000250|UniProtKB:Q6IMP4}.
uniprot
proteins
transmembrane_region
TRANSMEM 54..74; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351"; TRANSMEM 126..146; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351"; TRANSMEM 231..251; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351"; TRANSMEM 296..316; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351
uniprot
proteins