Eny2
entrez
223527
canonical
uniprot
Q9JIX0
canonical
ensembl
ENSMUSG00000022338
resolver
ensp
ENSMUSP00000052905
resolver
ensp
ENSMUSP00000154515
resolver
enst
ENSMUST00000060652
resolver
enst
ENSMUST00000226827
resolver
genesymbol
Eny2
resolver
genesymbol_syn
ENY2
resolver
uniprot
A0A2I3BRK6
resolver
uniprot_entry
A0A2I3BRK6_MOUSE
resolver
uniprot_entry
ENY2_MOUSE
resolver
amino_acid_sequence
MVVSKMNKDAQMRAAINQKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEHVTVDDLVAEITPKGRALVPDSVKKELLQRIRTFLAQHASL
uniprot
proteins
function
FUNCTION: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q9NPA8}.
uniprot
proteins
mass_dalton
11529
uniprot
proteins
protein_family
ENY2 family
uniprot
proteins
pubmed
11438676
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
101
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03046}.
uniprot
proteins