Ptov1
entrez
292888
canonical
uniprot
Q5U2W6
canonical
ensembl
ENSRNOG00000020358
resolver
ensembl
ENSRNOG00055005608
resolver
ensembl
ENSRNOG00060007581
resolver
ensembl
ENSRNOG00065028524
resolver
ensp
ENSRNOP00000027580
resolver
ensp
ENSRNOP00055006851
resolver
ensp
ENSRNOP00060009481
resolver
ensp
ENSRNOP00065040335
resolver
enst
ENSRNOT00000027580
resolver
enst
ENSRNOT00055009007
resolver
enst
ENSRNOT00060012511
resolver
enst
ENSRNOT00065049186
resolver
genesymbol
Ptov1
resolver
uniprot_entry
PTVO1_RAT
resolver
amino_acid_sequence
MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRSRSWPAGPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSAAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRRVIANQQQVLQRSLEQEQQQRGMGG
uniprot
proteins
function
FUNCTION: May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. {ECO:0000250|UniProtKB:Q86YD1}.
uniprot
proteins
mass_dalton
46849
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the CRL2(KLHDC2) complex, which recognizes the diglycine (Gly-Gly) at the C-terminus, leading to its degradation. Ubiquitinated by the CRL2(APPBP2) complex, which recognizes the Arg-Xaa-Xaa-Gly sequence at the C-terminus, leading to its degradation. {ECO:0000250|UniProtKB:Q86YD1}.
uniprot
proteins
protein_family
Mediator complex subunit 25 family
uniprot
proteins
protein_family
PTOV1 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
416
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86YD1}. Nucleus {ECO:0000250|UniProtKB:Q86YD1}. Cell membrane {ECO:0000250|UniProtKB:Q86YD1}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q86YD1}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts. {ECO:0000250|UniProtKB:Q86YD1}.
uniprot
proteins