LSM5
entrez
23658
canonical
uniprot
Q9Y4Y9
canonical
ensembl
ENSG00000106355
resolver
ensp
ENSP00000386363
resolver
ensp
ENSP00000386707
resolver
ensp
ENSP00000387126
resolver
ensp
ENSP00000410758
resolver
genesymbol
LSM5
resolver
hgnc
HGNC:17162
resolver
uniprot_entry
LSM5_HUMAN
resolver
amino_acid_sequence
MAANATTNPSQLLPLELVDKCIGSRIHIVMKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV
uniprot
proteins
function
FUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). {ECO:0000269|PubMed:10523320, ECO:0000269|PubMed:28781166}.
uniprot
proteins
mass_dalton
9937
uniprot
proteins
protein_family
SnRNP Sm proteins family
uniprot
proteins
pubmed
10369684
uniprot
proteins
pubmed
10523320
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
26912367
uniprot
proteins
pubmed
28781166
uniprot
proteins
sequence_length
91
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10523320, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28781166}.
uniprot
proteins