PSG9
entrez
5678
canonical
uniprot
Q00887
canonical
ensembl
ENSG00000183668
resolver
ensp
ENSP00000244293
resolver
ensp
ENSP00000270077
resolver
ensp
ENSP00000291752
resolver
ensp
ENSP00000396753
resolver
ensp
ENSP00000471453
resolver
enst
ENST00000291752
resolver
enst
ENST00000443718
resolver
enst
ENST00000593948
resolver
genesymbol
PSG9
resolver
genesymbol_syn
PSG11
resolver
hgnc
HGNC:9526
resolver
uniprot
B2R869
resolver
uniprot
B4DTI5
resolver
uniprot
E7EW65
resolver
uniprot
G3XAA7
resolver
uniprot
M0R0U8
resolver
uniprot
Q05DN5
resolver
uniprot
Q15227
resolver
uniprot
Q15236
resolver
uniprot
Q15237
resolver
uniprot
Q8WW78
resolver
uniprot
Q9UQ73
resolver
uniprot_entry
B4DTI5_HUMAN
resolver
uniprot_entry
E7EW65_HUMAN
resolver
uniprot_entry
G3XAA7_HUMAN
resolver
uniprot_entry
M0R0U8_HUMAN
resolver
uniprot_entry
PSG9_HUMAN
resolver
uniprot_entry
Q05DN5_HUMAN
resolver
uniprot_sec
B2R869
resolver
uniprot_sec
Q15227
resolver
uniprot_sec
Q15236
resolver
uniprot_sec
Q15237
resolver
uniprot_sec
Q8WW78
resolver
uniprot_sec
Q9UQ73
resolver
amino_acid_sequence
MGPLPAPSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQNLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTYTLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLYGPDLPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQKLFIPQITRNHSGLYACSVHNSATGKEISKSMTVKVSGPCHGDLTESQS
uniprot
proteins
function
FUNCTION: Binds to the small latent transforming growth factor-beta complex, consisting of the N-terminal TGFB1 latency-associated peptide (LAP) and the mature form of TGFB1, thereby leading to the activation of TGFB1 (PubMed:27389696). The activation of TGFB1 leads to stimulation of naive CD4(+) T-cells to increase FoxP3 expression and to an increase in the number of FoxP3(+) regulatory T-cells (PubMed:27389696). Induces the differentiation of a suppressive CD4(+)LAP(+)FoxP3(-) T-cell subset (PubMed:27389696). Induces the secretion of TGFB1 in macrophages, but not in activated CD4(+) T-cells (PubMed:27389696). May reduce the expression of several pro-inflammatory cytokines and chemokines by CD4(+) T-cells, including IL2 and IL6 (PubMed:27389696). {ECO:0000269|PubMed:27389696}.
uniprot
proteins
mass_dalton
48272
uniprot
proteins
protein_family
CEA family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1581354
uniprot
proteins
pubmed
1922019
uniprot
proteins
pubmed
2322584
uniprot
proteins
pubmed
2328001
uniprot
proteins
pubmed
2341148
uniprot
proteins
pubmed
27389696
uniprot
proteins
pubmed
28384346
uniprot
proteins
pubmed
7806221
uniprot
proteins
sequence_length
426
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins