NUDT11
entrez
55190
canonical
uniprot
Q96G61
canonical
ensembl
ENSG00000196368
resolver
ensp
ENSP00000365160
resolver
enst
ENST00000375992
resolver
genesymbol
NUDT11
resolver
genesymbol_syn
APS1
resolver
genesymbol_syn
DIPP3B
resolver
hgnc
HGNC:18011
resolver
uniprot
Q9NVN0
resolver
uniprot_entry
NUD11_HUMAN
resolver
uniprot_sec
Q9NVN0
resolver
amino_acid_sequence
MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
uniprot
proteins
ec_number
3.6.1.52
uniprot
proteins
ec_number
3.6.1.60
uniprot
proteins
function
FUNCTION: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. {ECO:0000269|PubMed:12105228}.
uniprot
proteins
mass_dalton
18559
uniprot
proteins
protein_family
DIPP subfamily
uniprot
proteins
protein_family
Nudix hydrolase family
uniprot
proteins
pubmed
12105228
uniprot
proteins
pubmed
12121577
uniprot
proteins
pubmed
12370170
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
21269460
uniprot
proteins
sequence_length
164
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12121577}.
uniprot
proteins