Liat1
entrez
74230
canonical
uniprot
Q810M6
canonical
ensembl
ENSMUSG00000053783
resolver
ensp
ENSMUSP00000063358
resolver
ensp
ENSMUSP00000284434
resolver
enst
ENSMUST00000066408
resolver
genesymbol
Liat1
resolver
uniprot_entry
LIAT1_MOUSE
resolver
amino_acid_sequence
MAGRGGTGAAEYGEEGEEEEEEEAREGGAEGSPGSKLPPIVGTASELAKRKVKKKKKKKKTKGSGKGDADKHHSRGRKNQPLSSSFHDILNPHKDHGLRAEPRDKEENRQTLPYSYSINHPCFAEIEDTLSSQINESLRWDGILTDPEAEKERIRIYKLNRRKRYRLMALKCFHSDPCVEESVENLPYLSDKDCSPCSKQPSSKGDHAHSYFEASKLLHPELATTVAE
uniprot
proteins
function
FUNCTION: Participates in nucleolar liquid-liquid phase separation (LLPS) through its N-terminal intrinsically disordered region (IDR) (PubMed:33443146). May be involved in ATE1-mediated N-terminal arginylation (PubMed:25369936). {ECO:0000269|PubMed:25369936, ECO:0000269|PubMed:33443146}.
uniprot
proteins
mass_dalton
25512
uniprot
proteins
post_translational_modification
PTM: Post-translationally modified by JMJD6 lysyl-hydroxylase activity at its Lys-rich domain, which inhibits its self-association and nucleolar localization. {ECO:0000269|PubMed:33443146}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
25369936
uniprot
proteins
pubmed
33443146
uniprot
proteins
sequence_length
228
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:33443146}. Cytoplasm {ECO:0000269|PubMed:33443146}. Note=Shuttles between the cytoplasm and nucleoplasm, a significant portion localizes to the nucleolus. {ECO:0000269|PubMed:33443146}.
uniprot
proteins