CTTNBP2NL
entrez
55917
canonical
uniprot
Q9P2B4
canonical
ensembl
ENSG00000143079
resolver
ensp
ENSP00000271277
resolver
ensp
ENSP00000532926
resolver
ensp
ENSP00000532927
resolver
ensp
ENSP00000532929
resolver
ensp
ENSP00000588327
resolver
ensp
ENSP00000637354
resolver
ensp
ENSP00000637355
resolver
ensp
ENSP00000637356
resolver
enst
ENST00000271277
resolver
enst
ENST00000862867
resolver
enst
ENST00000862868
resolver
enst
ENST00000862870
resolver
enst
ENST00000918268
resolver
enst
ENST00000967295
resolver
enst
ENST00000967296
resolver
enst
ENST00000967297
resolver
genesymbol
CTTNBP2NL
resolver
genesymbol_syn
KIAA1433
resolver
hgnc
HGNC:25330
resolver
uniprot
B3KMS5
resolver
uniprot
Q96B40
resolver
uniprot_entry
CT2NL_HUMAN
resolver
uniprot_sec
B3KMS5
resolver
uniprot_sec
Q96B40
resolver
amino_acid_sequence
MNLEKLSKPELLTLFSILEGELEARDLVIEALKAQHRDTFIEERYGKYNISDPLMALQRDFETLKEKNDGEKQPVCTNPLSILKVVMKQCKNMQERMLSQLAAAESRHRKVILDLEEERQRHAQDTAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERSRHKQLSSMLVLECKKATNKAAEEGQKAGELSLKLEKEKSRVSKLEEELAAERKRGLQTEAQVEKQLSEFDIEREQLRAKLNREENRTKTLKEEMESLKKIVKDLEASHQHSSPNEQLKKPVTVSKGTATEPLMLMSVFCQTESFPAERTHGSNIAKMTNTGLPGPATPAYSYAKTNGHCDPEIQTTRELTAGNNVENQVPPREKSVALAQEKPVENGGCPVGIETPVPMPSPLSSSGSSLSPSSTASSSLTSSPCSSPVLTKRLLGSSASSPGYQSSYQVGINQRFHAARHKFQSQADQDQQASGLQSPPSRDLSPTLIDNSAAKQLARNTVTQVLSRFTSQQGPIKPVSPNSSPFGTDYRNLANTANPRGDTSHSPTPGKVSSPLSPLSPGIKSPTIPRAERGNPPPIPPKKPGLTPSPSATTPLTKTHSQAASLTTAEDLASSCSSNTVVANGKDVELLLPTSS
uniprot
proteins
function
FUNCTION: Regulates lamellipodial actin dynamics in a CTTN-dependent manner (By similarity). Associates with core striatin-interacting phosphatase and kinase (STRIPAK) complex to form CTTNBP2NL-STRIPAK complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (PubMed:18782753). {ECO:0000250|UniProtKB:Q8SX68, ECO:0000269|PubMed:18782753}.
uniprot
proteins
mass_dalton
70158
uniprot
proteins
pubmed
10718198
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18782753
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
639
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q8SX68}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:Q99LJ0}.
uniprot
proteins