Ttll10
entrez
330010
canonical
uniprot
A4Q9F3
canonical
ensembl
ENSMUSG00000029074
resolver
ensp
ENSMUSP00000055671
resolver
ensp
ENSMUSP00000139316
resolver
enst
ENSMUST00000051509
resolver
enst
ENSMUST00000184348
resolver
genesymbol
Ttll10
resolver
uniprot
B1ASM0
resolver
uniprot
Q3V0K4
resolver
uniprot
V9GXT8
resolver
uniprot_entry
B1ASM0_MOUSE
resolver
uniprot_entry
TTL10_MOUSE
resolver
uniprot_entry
V9GXT8_MOUSE
resolver
uniprot_sec
Q3V0K4
resolver
amino_acid_sequence
MALHPQAGRPHRDGSEAQAEAAAQDLGRLPSPSKVGAAVCRIQGLGHRAARRPRRGIGTTSASRVPRPGALMPATRNRPRFIHCRGQPPRTRVSSKRSKRSRIHPCHTEVPGWTHEKQMGSSVKERLRPELSQLDQDADDLEEEEAARLPVTSPDGLLMEGDKQPSPGQGPFFYIGGTNGASIISNYCESKGWQRTQDSHCEDYKLKWCEIKCRDNYCSFREGQQLLFQLPNNKLLTTKIGLLSALREHARTLSKARMLPSTQTKVLKMEEFFPETYRLDIRDERQAFFALFDETQMWICKPTASNQGKGIFLIRSQEEAAALQAKTQSIEDDPIYRKMPFRAPQARVVQRYVQNPLLLDGKKFDVRSYMLIACAMPYMVFFGHGYARLTLSLYNPHSSDLSGHLTNQFMQKKSPLYTLLKESTVWTMEHLNRYINDKFRKTKGLPRDWVFTTFTKRMQQIMSHCFLAVKSKLECKLGYFDLIGCDFLIDENFKVWLLEMNANPALHTNCEVLKAVIPGVVIETLDLALETCQKSLHSQKMLPLLSQRRFVLLYNGETTDLWPRLASSRPLNRLPNPNPNPNPNANPHPHPHPNPHPHPNPHPNANPHPPRPTCEAASSALSSARAAISERPGARKSMPSRGAPVCTPRKSRLSDSSGSSIAESEPSLCSGSLEGSRDTAREPSLGPPEEEREEEQRSTSHRGS
uniprot
proteins
ec_number
6.3.2.-
uniprot
proteins
function
FUNCTION: Polyglycylase which modifies both tubulin and non-tubulin proteins, generating polyglycine side chains of variable lengths on the gamma-carboxyl groups of specific glutamate residues of target proteins (PubMed:18331838, PubMed:19427864, PubMed:19524510). Involved in the elongation step rather than the initiation step of the polyglycylation reaction (PubMed:18331838, PubMed:19427864, PubMed:19524510). Polyglycylates alpha-tubulin and beta-tubulin (PubMed:19427864, PubMed:19524510). Polyglycylates non-tubulin proteins such as nucleosome assembly protein NAP1 (PubMed:18331838). {ECO:0000269|PubMed:18331838, ECO:0000269|PubMed:19427864, ECO:0000269|PubMed:19524510}.
uniprot
proteins
mass_dalton
79250
uniprot
proteins
mutagenesis
MUTAGEN 499; /note="E->V: Loss of NAP1 polyglycylase activity."; /evidence="ECO:0000269|PubMed:18331838
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17499049
uniprot
proteins
pubmed
18331838
uniprot
proteins
pubmed
19427864
uniprot
proteins
pubmed
19524510
uniprot
proteins
sequence_length
704
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19427864, ECO:0000269|PubMed:19524510}. Cell projection, cilium {ECO:0000305}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000305}.
uniprot
proteins