Ptpn7
entrez
320139
canonical
uniprot
Q8BUM3
canonical
ensembl
ENSMUSG00000031506
resolver
ensp
ENSMUSP00000045803
resolver
ensp
ENSMUSP00000129474
resolver
ensp
ENSMUSP00000141133
resolver
enst
ENSMUST00000049449
resolver
enst
ENSMUST00000167080
resolver
enst
ENSMUST00000187985
resolver
genesymbol
Ptpn7
resolver
uniprot_entry
PTN7_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited upon FCER1A triggering. {ECO:0000269|PubMed:20157115}.
uniprot
proteins
amino_acid_sequence
MVQACEGRSRAQLPTLSLGADMTQPPPTKAPAKKHVRLQERRGSSVALMLDVQSLGTVEPICSVNTPREVTLHFLRTAGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPTEEEAYGPFQIRIQDMKEHPEYTVRQLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPEPNP
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: May play a role in the regulation of T and B-lymphocyte development and signal transduction. {ECO:0000250}.
uniprot
proteins
mass_dalton
40351
uniprot
proteins
post_translational_modification
PTM: Oxidized at active site cysteine. Treatment with pervanadate (vanadate and H(2)O(2)) or with antigen enhanced oxidation of active site cysteine. {ECO:0000269|PubMed:20157115}.
uniprot
proteins
protein_family
Non-receptor class subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20157115
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20157115}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20157115}. Note=Oxidized form is preferentially associated with actin cytoskeleton.
uniprot
proteins