G6PC2
entrez
57818
canonical
uniprot
Q9NQR9
canonical
ensembl
ENSG00000152254
resolver
ensembl
ENSG00000278373
resolver
ensp
ENSP00000364512
resolver
ensp
ENSP00000396939
resolver
genesymbol
G6PC2
resolver
genesymbol_syn
IGRP
resolver
hgnc
HGNC:28906
resolver
uniprot
E9PAX2
resolver
uniprot
Q6AHZ0
resolver
uniprot_entry
G6PC2_HUMAN
resolver
uniprot_sec
E9PAX2
resolver
uniprot_sec
Q6AHZ0
resolver
amino_acid_sequence
MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWVAVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAALSHTVCGMDKFSITLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLFLFAVGFYLLLRVLNIDLLWSVPIAKKWCANPDWIHIDTTPFAGLVRNLGVLFGLGFAINSEMFLLSCRGGNNYTLSFRLLCALTSLTILQLYHFLQIPTHEEHLFYVLSFCKSASIPLTVVAFIPYSVHMLMKQSGKKSQ
uniprot
proteins
ec_number
3.1.3.9
uniprot
proteins
function
FUNCTION: May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
40580
uniprot
proteins
mutagenesis
MUTAGEN 50; /note="N->A: No effect on N-glycosylation."; /evidence="ECO:0000269|PubMed:15044018"; MUTAGEN 92; /note="N->A: Loss of N-glycosylation."; /evidence="ECO:0000269|PubMed:15044018"; MUTAGEN 287; /note="N->A: No effect on N-glycosylation."; /evidence="ECO:0000269|PubMed:15044018
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
uniprot
proteins
post_translational_modification
PTM: N-glycosylated; the non-glycosylated form is more unstable and is degraded through the proteasome. {ECO:0000269|PubMed:15044018}.
uniprot
proteins
protein_family
Glucose-6-phosphatase family
uniprot
proteins
pubmed
11297555
uniprot
proteins
pubmed
14722102
uniprot
proteins
pubmed
15044018
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16520917
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18451265
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15044018}; Multi-pass membrane protein {ECO:0000269|PubMed:15044018}.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 57..77; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 116..136; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 147..167; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 169..189; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 212..232; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 262..282; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 294..314; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 319..339; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins