CD34
entrez
947
canonical
uniprot
P28906
canonical
ensembl
ENSG00000174059
resolver
ensp
ENSP00000310036
resolver
ensp
ENSP00000348916
resolver
genesymbol
CD34
resolver
hgnc
HGNC:1662
resolver
uniprot
A8K664
resolver
uniprot
Q15970
resolver
uniprot
Q15971
resolver
uniprot
Q5JTA3
resolver
uniprot
Q5JTA4
resolver
uniprot
Q9UJB1
resolver
uniprot_entry
CD34_HUMAN
resolver
uniprot_sec
A8K664
resolver
uniprot_sec
Q15970
resolver
uniprot_sec
Q15971
resolver
uniprot_sec
Q5JTA3
resolver
uniprot_sec
Q5JTA4
resolver
uniprot_sec
Q9UJB1
resolver
amino_acid_sequence
MLVRRGARAGPRMPRGWTALCLLSLLPSGFMSLDNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYSQKTLIALVTSGALLAVLGITGYFLMNRRSWSPTGERLGEDPYYTENGGGQGYSSGPGTSPEAQGKASVNRGAQENGTGQATSRNGHSARQHVVADTEL
uniprot
proteins
function
FUNCTION: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
uniprot
proteins
mass_dalton
40716
uniprot
proteins
post_translational_modification
PTM: Highly glycosylated.; PTM: Phosphorylated on serine residues by PKC. {ECO:0000269|PubMed:1694174}.
uniprot
proteins
protein_family
CD34 family
uniprot
proteins
pubmed
1370171
uniprot
proteins
pubmed
1374051
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
1694174
uniprot
proteins
pubmed
2462139
uniprot
proteins
pubmed
7678811
uniprot
proteins
sequence_length
385
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 291..311; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins