Q9D6K5
uniprot
Q9D6K5
canonical
amino_acid_sequence
MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKEDGAAAQDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGCAVSLRVQHRLPVQNGPIVHRGEGEPSGVPVAMVLLPVFALTMVAVWAFVRYRKQL
uniprot
proteins
function
FUNCTION: Isoform 1 regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction. Isoform 2 and isoform 3 show a stimulatory affect on activin-induced signal transduction and enhance activin type 2 expression at the cell surface. {ECO:0000269|PubMed:11882656, ECO:0000269|PubMed:16648306}.
uniprot
proteins
mass_dalton
15815
uniprot
proteins
pubmed
11882656
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16648306
uniprot
proteins
pubmed
17907296
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
145
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9WVJ4}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q9WVJ4}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9WVJ4}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11882656}.
uniprot
proteins
transmembrane_region
TRANSMEM 118..138; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins