Mtatp8
entrez
17706
canonical
uniprot
P03930
canonical
ensembl
ENSMUSG00000064356
resolver
ensp
ENSMUSP00000080995
resolver
enst
ENSMUST00000082407
resolver
genesymbol
Mtatp8
resolver
genesymbol_syn
Atp8
resolver
genesymbol_syn
mt-Atp8
resolver
uniprot_entry
ATP8_MOUSE
resolver
amino_acid_sequence
MPQLDTSTWFITIISSMITLFILFQLKVSSQTFPLAPSPKSLTTMKVKTPWELKWTKIYLPHSLPQQ
uniprot
proteins
function
FUNCTION: Subunit 8, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (By similarity). {ECO:0000250|UniProtKB:P03928, ECO:0000250|UniProtKB:P19483}.
uniprot
proteins
mass_dalton
7766
uniprot
proteins
protein_family
ATPase protein 8 family
uniprot
proteins
pubmed
12954771
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
7332926
uniprot
proteins
sequence_length
67
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane; Single-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 8..24; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins