Sun3
entrez
194974
canonical
uniprot
Q5SS91
canonical
ensembl
ENSMUSG00000040985
resolver
ensp
ENSMUSP00000045199
resolver
ensp
ENSMUSP00000099973
resolver
genesymbol
Sun3
resolver
genesymbol_syn
Sunc1
resolver
uniprot
E9LV81
resolver
uniprot
Q8BHY0
resolver
uniprot_entry
E9LV81_MOUSE
resolver
uniprot_entry
SUN3_MOUSE
resolver
uniprot_sec
Q8BHY0
resolver
amino_acid_sequence
MLTRSWKIILSTVFISTFLLVGLLNHQWLKETEFPQKPRQLYTVIAEYGSRLYNYQARLRMPKEQQELLKKESQTLENNFREILFLIEQIDVLKALLKDMKDGVHNHSLPVHRDAVQDQATTDVLDEEMSNLVHYVLKKFRGDQIQLADYALKSAGASVIEAGTSESYKNNKAKLYWHGIGFLNYEMPPDMILQPDVHPGKCWAFPGSQGHILIKLARKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGVMKKCEGEEIFLGQFIYNKMEATIQTFELQNEASESLLCVKLQILSNWGHPKYTCLYRFRVHGIPSDYT
uniprot
proteins
function
FUNCTION: As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenesis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette. {ECO:0000305|PubMed:20711465}.
uniprot
proteins
mass_dalton
36758
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20711465
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26621829
uniprot
proteins
sequence_length
320
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus envelope {ECO:0000269|PubMed:20711465}. Nucleus inner membrane {ECO:0000305}. Note=Localized to spermatid nucleus posterior pole lateral regions excluding the implantation fossa during entire sperm head elongation. {ECO:0000269|PubMed:20711465}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..29; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins