Slc44a4
entrez
294255
canonical
uniprot
Q6MG71
canonical
ensembl
ENSRNOG00000000878
resolver
ensembl
ENSRNOG00065024752
resolver
ensp
ENSRNOP00000001174
resolver
ensp
ENSRNOP00065034852
resolver
enst
ENSRNOT00000001174
resolver
enst
ENSRNOT00065042590
resolver
genesymbol
Slc44a4
resolver
genesymbol_syn
Ctl4
resolver
genesymbol_syn
Ng22
resolver
genesymbol_syn
TPPT1
resolver
uniprot_entry
CTL4_RAT
resolver
amino_acid_sequence
MGKKQKENEAYGNSAKYDPSFRGPIKNRGCTDIICCVLFLVFILGYIVVGLVAWVYGDPRQVLYPRNSTGAYCGVGDNKDKPYVLYFNILSCAAAINVISIAENGLQCPTPQVCVSSCPQTPWVVEGFQLSNTVGDVYKEYRNFCVPAVSPDMVVMDSLQKGLCPSFLLPSTPALGRCFPLPNINFTLPEQLQINNTTVSKGISGLLDSINARDVSVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAAPLVLLLIVGVLAVLAYGIYHCWQQYRELRDQGVSITQLGFTANLSAYQNVKETWLAALIILAVLEGVLLLMLIFLRQRIRIAIALLKEASRAVGQMMSTMFYPLVTFVLLVICIGYWAVTALYLATSGQPQYVYWVHNTSTPGCEKVLVNVSCDPMAPLNSSCPELKCTFTGYSSSGLAQRSLFNLQIYGILGLFWTVNWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLSSAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGSQNPVARCIICCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNVVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIKGLGKDFKNPDLNYYWLPIMTSIMGAYVIASGFFSVFGMCVDTLFLCFLEDLERNDGSQERPYYMPKALLKILGKKNEVPTGGKNRKK
uniprot
proteins
function
FUNCTION: Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity). {ECO:0000250|UniProtKB:Q53GD3, ECO:0000250|UniProtKB:Q7T2B0}.
uniprot
proteins
mass_dalton
78737
uniprot
proteins
post_translational_modification
PTM: N-glycosylated; N-glycosylation of Asn-67 and Asn-391 is required for a proper thiamine pyrophosphate uptake. {ECO:0000250|UniProtKB:Q53GD3}.
uniprot
proteins
protein_family
CTL (choline transporter-like) family
uniprot
proteins
pubmed
15060004
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15715662
uniprot
proteins
sequence_length
707
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q53GD3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53GD3}. Apical cell membrane {ECO:0000250|UniProtKB:Q53GD3}.
uniprot
proteins
transmembrane_region
TRANSMEM 33..53; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 228..248; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 251..271; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 357..377; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 453..473; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 499..519; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 558..578; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 595..615; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 636..656; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins