Drc1
entrez
362712
canonical
uniprot
Q5XI65
canonical
ensembl
ENSRNOG00000024905
resolver
ensembl
ENSRNOG00055019106
resolver
ensembl
ENSRNOG00060011831
resolver
ensp
ENSRNOP00000031362
resolver
ensp
ENSRNOP00055026404
resolver
ensp
ENSRNOP00060015709
resolver
enst
ENSRNOT00000036815
resolver
enst
ENSRNOT00055032603
resolver
enst
ENSRNOT00060020027
resolver
genesymbol
Drc1
resolver
genesymbol_syn
Ccdc164
resolver
uniprot_entry
DRC1_RAT
resolver
amino_acid_sequence
MNPSGSIGVLEQNGEEHLAAPILGPSVNSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVAADIREIHRRVEEEETKRQRLEKLENEVKTSQDKFDEITSKWEEGRQKRIPQELWEMLNNQQVHCAGLVEDKNKLISELQQELKIKDDQYVKDLKKQSEDITVLLERMEEQVKSVMKNFRQELNYIEKAFESERQELLTTNKKKWERALQAHNAKELEYLINRMKRVEDYEKQLNRQRVWDCEEYNSIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDILNNLRTKYSKQIKQFQEDNQSLTSDYKRLVTQFKDLQKAIRHFIIIDQDKFREIWLMNEAEAKELAQRAFDVDKIIHSQHLGLPWKIPNFWFLNNVGPISLQQQQKSVTQILEELLLQSEDEGTETAMSEDESYMDLPNQVSAKTTKKILVLLCDESGFLIESKLLSLLLPLEKSECYLLRLDAIFSALGIESEDDLYKMVNFFLRFKAHHLSSAQVSISTHSNAERTSLVSALQHMSLMSQTDRRSSASKSDGDPTELEDQQGSDNGSLMGRELVEQEDLSSPMFIHPNDVLKILDAFVTGLKKPKDARPVQRLKKDTRNNLKDTEYWESLAMVIPFSKQNLWDALFKALEKYYLVLTQRAKLLMENDSLEQQNAEMQSLLQQYLQAKVNLELQVPPTQGFRMPSK
uniprot
proteins
function
FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. {ECO:0000250|UniProtKB:P0DL09, ECO:0000250|UniProtKB:Q96MC2}.
uniprot
proteins
mass_dalton
88310
uniprot
proteins
protein_family
DRC1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
754
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:P0DL09}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:P0DL09}.
uniprot
proteins