DRC3
entrez
83450
canonical
uniprot
Q9H069
canonical
ensembl
ENSG00000171962
resolver
ensp
ENSP00000382136
resolver
ensp
ENSP00000382140
resolver
ensp
ENSP00000462661
resolver
ensp
ENSP00000557485
resolver
ensp
ENSP00000557487
resolver
ensp
ENSP00000557489
resolver
ensp
ENSP00000686806
resolver
genesymbol
DRC3
resolver
genesymbol_syn
LRRC48
resolver
hgnc
HGNC:25384
resolver
uniprot
A8KAE6
resolver
uniprot
B3KSC6
resolver
uniprot
Q86SF9
resolver
uniprot
Q86W73
resolver
uniprot
Q8IWG0
resolver
uniprot_entry
B3KSC6_HUMAN
resolver
uniprot_entry
DRC3_HUMAN
resolver
uniprot_sec
A8KAE6
resolver
uniprot_sec
Q86SF9
resolver
uniprot_sec
Q86W73
resolver
uniprot_sec
Q8IWG0
resolver
amino_acid_sequence
MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAFVEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISELFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDLPNDLRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTRINSWCTRLIDRIHKDEIMRNRKRVKEINQYIDHMQSELDNLECGDILD
uniprot
proteins
function
FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. {ECO:0000250|UniProtKB:A8IVX2}.
uniprot
proteins
mass_dalton
61054
uniprot
proteins
protein_family
DRC3 family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23354437
uniprot
proteins
pubmed
27120127
uniprot
proteins
pubmed
34169321
uniprot
proteins
sequence_length
523
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:23354437}. Cell projection, cilium {ECO:0000269|PubMed:27120127}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A8IVX2}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9D5E4}.
uniprot
proteins