Grip2
entrez
171571
canonical
uniprot
Q9WTW1
canonical
ensembl
ENSRNOG00000009726
resolver
ensp
ENSRNOP00000013232
resolver
ensp
ENSRNOP00000041016
resolver
ensp
ENSRNOP00000101025
resolver
ensp
ENSRNOP00000105286
resolver
enst
ENSRNOT00000159958
resolver
genesymbol
Grip2
resolver
uniprot
A0ABK0LUL2
resolver
uniprot
O88961
resolver
uniprot
Q9WU36
resolver
uniprot_entry
A0ABK0LUL2_RAT
resolver
uniprot_entry
GRIP2_RAT
resolver
uniprot_sec
O88961
resolver
uniprot_sec
Q9WU36
resolver
amino_acid_sequence
MLAVSLKWRLGVVRRRPKDDGPYSKGGKDTAGTDGALVCRRQSIPEEFRGITMVELIKREGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIRLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGAHEDLHKSRPLVLTYVRPGGPADREGSLKVGDRLLSIDGIPLHGASHATAIATLQQCSHEALFQVEYDVATPDTVANASGPLVVEIAKTPGSALGISLTTGSHRNKPAITIDRIKPASVVDRSGALHAGDHILAIDGTSTEHCSLVEATKLLASVTEKVRLEILPAPQSRRPLKPPEAVRIQRSEQLHHWDPCVPSCHSPRPSHCRAPTWAPGGQDQSRSVSSTPFSSPTMNPAFPCANASTLPRGPMSPRTTAGRRRQRRKEHRSSLSLASSTVGPGGQIVHTETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPLVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALARKVVLEIEFDVAESVIPSSGTFHVKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDHCPMEYAVQILRQCEDLVKLKIRKDEDNSDEQESSGAVSYTVELKRYGGPLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRQSGSLSEASDVDEDPPEALKGGLLTTHFSPAVPSVDSAVESWGSSATEGGFGGSGSYTPQVAVRSVTPQEWRSSRLKSSPPPLEPRRTSYTPGPTDESFPEEEEGDWEPPMSPAPGPAREEGFWRVLGEALEDLESCGQSELLRELEASIMTGTVQSVAVDGRPGSRPWRRSREVGTSPEDLQELLLPTPLEMHRVTLHKDPVRNDFGFSVSDGLLEKGVYVHTVRIDGPAQHGGLQPFDRLLQVNHVRTRDFDCCLAVPLLAEAGDILELVVSRNPLAQSRRTPGAPGPSSPQMI
uniprot
proteins
function
FUNCTION: May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
uniprot
proteins
mass_dalton
112488
uniprot
proteins
post_translational_modification
PTM: Palmitoylation of isoform 4 mediates membrane location. {ECO:0000269|PubMed:11978826}.
uniprot
proteins
protein_family
GRIP2 family
uniprot
proteins
pubmed
10197531
uniprot
proteins
pubmed
10414981
uniprot
proteins
pubmed
10436050
uniprot
proteins
pubmed
10896157
uniprot
proteins
pubmed
11978826
uniprot
proteins
pubmed
12458226
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9768844
uniprot
proteins
sequence_length
1043
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane. Postsynaptic density. Note=Isoform 1 was found in synaptic plasma membrane and postsynaptic density.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Membrane; Peripheral membrane protein. Synapse. Note=Isoform 2 was found at excitatory synapses and also at non-synaptic membranes and within intracellular compartments.; SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane. Postsynaptic density. Cell projection, dendritic spine. Endoplasmic reticulum. Cytoplasm, cytoskeleton. Note=Isoform 3 was found in synaptic plasma membrane and postsynaptic density. Isoform 3 was also found in dendrites where it was associated with microtubules, endoplasmic reticulum and dendritic spines.; SUBCELLULAR LOCATION: [Isoform 4]: Membrane; Peripheral membrane protein. Note=Isoform 4 was exclusively membrane associated. {ECO:0000269|PubMed:11978826}.
uniprot
proteins