Asic4
entrez
63882
canonical
uniprot
Q9JHS6
canonical
ensembl
ENSRNOG00000019985
resolver
ensp
ENSRNOP00000027135
resolver
enst
ENSRNOT00000027135
resolver
genesymbol
Asic4
resolver
genesymbol_syn
Accn4
resolver
genesymbol_syn
Spasic
resolver
uniprot
G3V8N2
resolver
uniprot
Q9QYV9
resolver
uniprot_entry
ASIC4_RAT
resolver
uniprot_entry
G3V8N2_RAT
resolver
uniprot_sec
Q9QYV9
resolver
amino_acid_sequence
MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGPAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWVLALLTSLAAFLYQAASLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQKQRLTYLPQPWGNCRAESKLREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEISMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLRTSTGGISTLGLQELKEQSPCPNRGRAEGGGASNLLPNHHHPHGPPGSLFEDFAC
uniprot
proteins
function
FUNCTION: Does not exhibit measurable stand-alone pH-gated sodium channel activity but may form pH-gated heterotrimeric sodium channels. Its activity could also depend on alternative gating mechanisms. {ECO:0000269|PubMed:10852210, ECO:0000269|PubMed:10923674}.
uniprot
proteins
mass_dalton
59325
uniprot
proteins
mutagenesis
MUTAGEN 441; /note="G->A: No effect on channel function."; /evidence="ECO:0000269|PubMed:10852210
uniprot
proteins
protein_family
ASIC4 subfamily
uniprot
proteins
protein_family
Amiloride-sensitive sodium channel (TC 1.A.6) family
uniprot
proteins
pubmed
10852210
uniprot
proteins
pubmed
10923674
uniprot
proteins
sequence_length
539
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P78348}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 69..89; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 439..459; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins