Alb
entrez
24186
canonical
uniprot
P02770
canonical
ensembl
ENSRNOG00000002911
resolver
ensp
ENSRNOP00000003921
resolver
genesymbol
Alb
resolver
uniprot
P11382
resolver
uniprot
Q5U3X3
resolver
uniprot_entry
ALBU_RAT
resolver
uniprot_sec
P11382
resolver
uniprot_sec
Q5U3X3
resolver
amino_acid_sequence
MKWVTFLLLLFISGSAFSRGVFRREAHKSEIAHRFKDLGEQHFKGLVLIAFSQYLQKCPYEEHIKLVQEVTDFAKTCVADENAENCDKSIHTLFGDKLCAIPKLRDNYGELADCCAKQEPERNECFLQHKDDNPNLPPFQRPEAEAMCTSFQENPTSFLGHYLHEVARRHPYFYAPELLYYAEKYNEVLTQCCTESDKAACLTPKLDAVKEKALVAAVRQRMKCSSMQRFGERAFKAWAVARMSQRFPNAEFAEITKLATDVTKINKECCHGDLLECADDRAELAKYMCENQATISSKLQACCDKPVLQKSQCLAEIEHDNIPADLPSIAADFVEDKEVCKNYAEAKDVFLGTFLYEYSRRHPDYSVSLLLRLAKKYEATLEKCCAEGDPPACYGTVLAEFQPLVEEPKNLVKTNCELYEKLGEYGFQNAVLVRYTQKAPQVSTPTLVEAARNLGRVGTKCCTLPEAQRLPCVEDYLSAILNRLCVLHEKTPVSEKVTKCCSGSLVERRPCFSALTVDETYVPKEFKAETFTFHSDICTLPDKEKQIKKQTALAELVKHKPKATEDQLKTVMGDFAQFVDKCCKAADKDNCFATEGPNLVARSKEALA
uniprot
proteins
function
FUNCTION: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (By similarity). Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity). {ECO:0000250|UniProtKB:P02768, ECO:0000250|UniProtKB:P02769}.
uniprot
proteins
mass_dalton
68731
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by FAM20C in the extracellular medium. {ECO:0000250|UniProtKB:P02768}.
uniprot
proteins
protein_family
ALB/AFP/VDB family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2437111
uniprot
proteins
pubmed
564345
uniprot
proteins
pubmed
7017712
uniprot
proteins
pubmed
7358734
uniprot
proteins
pubmed
80265
uniprot
proteins
pubmed
893447
uniprot
proteins
pubmed
956149
uniprot
proteins
sequence_length
608
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins