B4galt6
entrez
56386
canonical
uniprot
Q9WVK5
canonical
ensembl
ENSMUSG00000056124
resolver
ensp
ENSMUSP00000066515
resolver
enst
ENSMUST00000070080
resolver
genesymbol
B4galt6
resolver
uniprot
Q3UUA9
resolver
uniprot_entry
B4GT6_MOUSE
resolver
uniprot_entry
Q3UUA9_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by EDTA. {ECO:0000250|UniProtKB:O88419}.
uniprot
proteins
amino_acid_sequence
MSALKRMMRVSNRSLIAFIFFFSLSTSCLYFIYVAPGIANTYLFMVQARGIMLRENVKTIGHMIRLYTNKNTTLNGTDYPEGNNTSDYLVQTTTYLPQNFTYLPHLPCPEKLPYMRGFLSVNVSEISFDEVHQLFSKDSEIGPGGHWRPKDCKPRWKVAVLIPFRNRHEHLPIFFLHLIPMLQKQRLEFAFYVIEQTGTQPFNRAMLFNVGFKEAMKDRAWDCVIFHDVDHLPENDRNYYGCGEMPRHFAAKLDKYMYILPYKEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVHYAGYNVTRPEGDLGKYISIPHHHRGEVQFLGRYKLLRYSKERQYIDGLNNLLYTPKILVDRLYTNISVNLMPELAPIEDY
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
ec_number
2.4.1.274
uniprot
proteins
function
FUNCTION: Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:23882130, PubMed:30114188). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (PubMed:30114188). {ECO:0000269|PubMed:23882130, ECO:0000269|PubMed:30114188}.
uniprot
proteins
mass_dalton
44759
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.; PATHWAY: Sphingolipid metabolism.
uniprot
proteins
protein_family
Glycosyltransferase 7 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23882130
uniprot
proteins
pubmed
30114188
uniprot
proteins
sequence_length
382
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:P15291}; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack. {ECO:0000250|UniProtKB:P15291}.
uniprot
proteins
transmembrane_region
TRANSMEM 16..35; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins