Trmt1l
entrez
98685
canonical
uniprot
A2RSY6
canonical
ensembl
ENSMUSG00000053286
resolver
ensp
ENSMUSP00000068309
resolver
ensp
ENSMUSP00000256908
resolver
ensp
ENSMUSP00000256923
resolver
enst
ENSMUST00000065625
resolver
genesymbol
Trmt1l
resolver
uniprot
A0A0R4J0U8
resolver
uniprot
Q0VGB9
resolver
uniprot
Q3UFG1
resolver
uniprot
Q3UKB0
resolver
uniprot
Q8C2S4
resolver
uniprot
Q8CI50
resolver
uniprot
Q8R203
resolver
uniprot
Q9CT68
resolver
uniprot_entry
A0A0R4J0U8_MOUSE
resolver
uniprot_entry
TRM1L_MOUSE
resolver
uniprot_sec
Q0VGB9
resolver
uniprot_sec
Q3UFG1
resolver
uniprot_sec
Q3UKB0
resolver
uniprot_sec
Q8C2S4
resolver
uniprot_sec
Q8CI50
resolver
uniprot_sec
Q8R203
resolver
uniprot_sec
Q9CT68
resolver
amino_acid_sequence
MENMAEEELLPQEKEEAQVRVPTPAPDSAPVPAPAADTALDSAPTPDSDPAPALAPAPAPALSPSLASVPEEAESKRHISIQRRLADLEKLAFGTEGDVDSASSLNSDNPGTENSQTCPLCPKEKFRAYSSHKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAKERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEDDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESIHHGLDDIQPLIKTLIFESECTPQSQCSTHAPSNTNKQEENGVFVKTTDDTTIDIYSAQGKRKSNEMAINLAKKQKTDASTAHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGAQSEGQMPPAAEDTVTDRVEMSVSDKAEASGCRRW
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Specifically dimethylates a single guanine residue at position 27 of tRNA(Tyr) using S-adenosyl-L-methionine as donor of the methyl groups (By similarity). Dimethylation at position 27 of tRNA(Tyr) is required for efficient translation of tyrosine codons (By similarity). Also required to maintain 3-(3-amino-3-carboxypropyl)uridine (acp3U) in the D-loop of several cytoplasmic tRNAs (By similarity). May play a role in motor coordination and exploratory behavior (PubMed:17198746). {ECO:0000250|UniProtKB:Q7Z2T5, ECO:0000269|PubMed:17198746}.
uniprot
proteins
mass_dalton
80861
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
Trm1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17198746
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
728
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q7Z2T5}.
uniprot
proteins