C1galt1
entrez
94192
canonical
uniprot
Q9JJ06
canonical
ensembl
ENSMUSG00000042460
resolver
ensp
ENSMUSP00000047931
resolver
enst
ENSMUST00000040159
resolver
genesymbol
C1galt1
resolver
genesymbol_syn
Plt1
resolver
uniprot
Q6P218
resolver
uniprot
Q8R0Z7
resolver
uniprot_entry
C1GLT_MOUSE
resolver
uniprot_sec
Q6P218
resolver
uniprot_sec
Q8R0Z7
resolver
amino_acid_sequence
MASKSWLNFLVFLCGSAIGFFLCSQLLSILLREEAAIQPNMLHNDPHARHSDDNGHSHLKGQMNFNADSSQHKDENIDVAENLYQKVKILCWVMTSPQNLEKKAKHVKATWAQRCNKVLFMSSEENQDFPTVGLKTKEGREQLYWKTIKAFQYVHDHYLEDADWFMKADDDTYVIVDNLRWLLSKYNPEQPIYFGRRFKPYVKQGYMSGGAGYVLSKEALRRFVNAFKTEKCTHSSSIEDLALGRCMEIINVEAGDSRDTIGKETFHPFVPEHHLIKGYLPKTFWYWNYNYYPPIEGPGCCSDIAVSFHYVDGTTMYELEYLVYHLRPYGYLYRYQPALPENILKEINQVNRKEDTKIKLGNP
uniprot
proteins
ec_number
2.4.1.122
uniprot
proteins
function
FUNCTION: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. {ECO:0000250|UniProtKB:Q7K237, ECO:0000250|UniProtKB:Q9NS00, ECO:0000269|PubMed:14745002, ECO:0000269|PubMed:17062753}.
uniprot
proteins
mass_dalton
42304
uniprot
proteins
mutagenesis
MUTAGEN 321; /note="Y->N: In plt1; loss of function inducing thrombocytopenia and kidney disease."; /evidence="ECO:0000269|PubMed:17062753
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q9NS00}.
uniprot
proteins
protein_family
Beta3-Gal-T subfamily
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
11677243
uniprot
proteins
pubmed
14745002
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17062753
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
363
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q9JJ05}; Single-pass type II membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 9..29; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins