Slc25a40
entrez
319653
canonical
uniprot
Q8BGP6
canonical
ensembl
ENSMUSG00000054099
resolver
ensp
ENSMUSP00000067611
resolver
ensp
ENSMUSP00000130630
resolver
ensp
ENSMUSP00000322397
resolver
ensp
ENSMUSP00000322400
resolver
genesymbol
Slc25a40
resolver
uniprot
Q3UVZ5
resolver
uniprot
Q8BXT8
resolver
uniprot_entry
S2540_MOUSE
resolver
uniprot_sec
Q3UVZ5
resolver
uniprot_sec
Q8BXT8
resolver
amino_acid_sequence
MEPETEGPPPTIPVTPLQQMIASCTGAVLTSLMVTPLDVVKIRLQAQNNPFPKGKCFLYSNGLMDHMCVCEEESKKAWYKKPGNFRGTLDAFLKILRNEGIKSLWSGLPPTLVMAIPATVIYFTCYEQLSAFLKTKLGENETRIPIVAGVVARFGAVTVISPLELIRTKVQSKKFSYKELYQFVSMRVSEDGWISLWKGWAPTILRDVPFSAMYWYNYENLKRWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTNEYCKFPAPLDMSTWTIMKNIVADKGFSGLFTGLIPRLVKIVPACAIMISSYELGKSFFQKQNVESR
uniprot
proteins
function
FUNCTION: Probable mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles (By similarity). Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis (PubMed:34707288). {ECO:0000250|UniProtKB:Q8TBP6, ECO:0000269|PubMed:34707288}.
uniprot
proteins
mass_dalton
37964
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
34707288
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9BZJ4}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..40; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 146..166; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 200..221; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 240..260; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 299..319; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins