GLYATL2
entrez
219970
canonical
uniprot
Q8WU03
canonical
ensembl
ENSG00000156689
resolver
ensp
ENSP00000287275
resolver
ensp
ENSP00000434277
resolver
enst
ENST00000287275
resolver
enst
ENST00000532258
resolver
genesymbol
GLYATL2
resolver
hgnc
HGNC:24178
resolver
uniprot
A5LGC7
resolver
uniprot
Q86WC3
resolver
uniprot
Q96AT2
resolver
uniprot_entry
GLYL2_HUMAN
resolver
uniprot_sec
A5LGC7
resolver
uniprot_sec
Q86WC3
resolver
uniprot_sec
Q96AT2
resolver
amino_acid_sequence
MLVLHNSQKLQILYKSLEKSIPESIKVYGAIFNIKDKNPFNMEVLVDAWPDYQIVITRPQKQEMKDDQDHYTNTYHIFTKAPDKLEEVLSYSNVISWEQTLQIQGCQEGLDEAIRKVATSKSVQVDYMKTILFIPELPKKHKTSSNDKMELFEVDDDNKEGNFSNMFLDASHAGLVNEHWAFGKNERSLKYIERCLQDFLGFGVLGPEGQLVSWIVMEQSCELRMGYTVPKYRHQGNMLQIGYHLEKYLSQKEIPFYFHVADNNEKSLQALNNLGFKICPCGWHQWKCTPKKYC
uniprot
proteins
ec_number
2.3.1.13
uniprot
proteins
function
FUNCTION: Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine (PubMed:20305126, PubMed:22475485). Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine (PubMed:20305126). {ECO:0000269|PubMed:20305126, ECO:0000269|PubMed:22475485}.
uniprot
proteins
mass_dalton
34277
uniprot
proteins
post_translational_modification
PTM: Acetylation at Lys-19 drastically decreases the production of N-oleoyl and N-arachidonoyl glycines. {ECO:0000269|PubMed:22408254}.
uniprot
proteins
protein_family
Glycine N-acyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20305126
uniprot
proteins
pubmed
22408254
uniprot
proteins
pubmed
22475485
uniprot
proteins
sequence_length
294
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:20305126}.
uniprot
proteins