Dpp3
entrez
114591
canonical
uniprot
O55096
canonical
ensembl
ENSRNOG00000031485
resolver
ensembl
ENSRNOG00055020766
resolver
ensembl
ENSRNOG00060031747
resolver
ensembl
ENSRNOG00065033286
resolver
ensp
ENSRNOP00000026968
resolver
ensp
ENSRNOP00000097513
resolver
ensp
ENSRNOP00055028763
resolver
ensp
ENSRNOP00060045487
resolver
ensp
ENSRNOP00065047090
resolver
enst
ENSRNOT00055035474
resolver
enst
ENSRNOT00060055031
resolver
enst
ENSRNOT00065057237
resolver
genesymbol
Dpp3
resolver
uniprot
Q32Q87
resolver
uniprot_entry
DPP3_RAT
resolver
uniprot_sec
Q32Q87
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by spinorphin, an opioid peptide derived from hemoglobin. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAHHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSKAAQQHPEEVRSLWQTCGELMFSLEPRLRHLGLGKEGVTTYFSGDCAMEDAKLAQDFLDSQNLSAYNTRLFKVVGQEGKYHYEVRLASVLNTEPALDSELTSKLKSYEFQGNHFQVTRGDYAPILQKVVEHLEKAKAYAANSHQEQMLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKDMSAKFERLVASAEQLLKELPWPPAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATKREKLTFMEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLNPQVLQIFGFEGTDAEDVIYVNWLNMVRAGLLALEFYTPETANWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVHLDRSKIRSVGKPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSEVQLVEYEASAAGLIRSFCERFPEDGPELEEVLTQLATADAQFWRDQVQEAPSGQA
uniprot
proteins
ec_number
3.4.14.4
uniprot
proteins
function
FUNCTION: Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (By similarity). Also cleaves Arg-Arg-beta-naphthylamide. {ECO:0000250|UniProtKB:Q9NY33}.
uniprot
proteins
mass_dalton
83039
uniprot
proteins
mutagenesis
MUTAGEN 176; /note="C->A: 25% to 35% of wild-type activity."; /evidence="ECO:0000269|PubMed:11027512"; MUTAGEN 176; /note="C->E,G: Loss of activity."; /evidence="ECO:0000269|PubMed:11027512"; MUTAGEN 450; /note="H->Y: Loss of activity and zinc binding."; /evidence="ECO:0000269|PubMed:10387075"; MUTAGEN 451; /note="E->A,D: Loss of activity."; /evidence="ECO:0000269|PubMed:10387075"; MUTAGEN 455; /note="H->Y: Loss of activity and zinc binding."; /evidence="ECO:0000269|PubMed:10387075
uniprot
proteins
protein_family
Peptidase M49 family
uniprot
proteins
pubmed
10387075
uniprot
proteins
pubmed
11027512
uniprot
proteins
pubmed
11209758
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9425109
uniprot
proteins
sequence_length
738
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins