Lrrc59
entrez
98238
canonical
uniprot
Q922Q8
canonical
ensembl
ENSMUSG00000020869
resolver
ensp
ENSMUSP00000021239
resolver
enst
ENSMUST00000021239
resolver
genesymbol
Lrrc59
resolver
uniprot
Q3TJ35
resolver
uniprot
Q3TLC7
resolver
uniprot
Q3TWT9
resolver
uniprot
Q3TX86
resolver
uniprot_entry
LRC59_MOUSE
resolver
uniprot_sec
Q3TJ35
resolver
uniprot_sec
Q3TLC7
resolver
uniprot_sec
Q3TWT9
resolver
uniprot_sec
Q3TX86
resolver
amino_acid_sequence
MTKAGSKGGNLRDKLDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAGDCLDEKQCKQCANKVLQHMKAVQADQERERQRRLEVEREAEKKREAKQQAKEAKERELRKREKAEEKERRRKEYDAQKASKREQEKKPKKEANQAPKSKSGSRPRKPPPRKHTRSWAVLKVLLLLLLLCVAGGLVVCRVTGLHQQPLCTSVNTIYDNAVQGLRHHEILQWVLQTDSQQ
uniprot
proteins
function
FUNCTION: Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
34877
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
307
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Microsome membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Nucleus envelope {ECO:0000250}. Note=Localization in the nuclear envelope depends upon the nuclear import machinery, including KPNB1. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 245..265; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins