Aplp2
entrez
11804
canonical
uniprot
Q06335
canonical
ensembl
ENSMUSG00000031996
resolver
ensp
ENSMUSP00000072428
resolver
ensp
ENSMUSP00000078694
resolver
ensp
ENSMUSP00000149023
resolver
ensp
ENSMUSP00000228145
resolver
enst
ENSMUST00000072634
resolver
genesymbol
Aplp2
resolver
genesymbol_syn
APLP2
resolver
genesymbol_syn
APPL2
resolver
uniprot
F6RI02
resolver
uniprot
Q60709
resolver
uniprot
Q64348
resolver
uniprot
Q80US7
resolver
uniprot_entry
APLP2_MOUSE
resolver
uniprot_entry
F6RI02_MOUSE
resolver
uniprot_entry
Q60709_MOUSE
resolver
uniprot_entry
Q64348_MOUSE
resolver
uniprot_sec
Q80US7
resolver
amino_acid_sequence
MAATGTAAAAATGKLLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDKRQCKSHIVIPFKCLVGEFVSDVLLVPDNCQFFHQERMEVCEKHQRWHTLVKEACLTEGLTLYSYGMLLPCGVDQFHGTEYVCCPQTKTVDSDSTMSKEEEEEEEDEEDEEEDYDLDKSEFPTEADLEDFTEAAADEEEEDEEEGEEVVEDRDYYYDPFKGDDYNEENPTEPSSEGTISDKEIVHDVKVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKTERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTSSISENPVDVRVSSEESEEIPPFHPLHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSKNKMDENMVIDETLDVKEMIFNAERVGGLEEEPESVGPLREDFSLSSNALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI
uniprot
proteins
function
FUNCTION: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein (By similarity). Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts. {ECO:0000250, ECO:0000269|PubMed:15677459}.
uniprot
proteins
mass_dalton
80467
uniprot
proteins
protein_family
APP family
uniprot
proteins
pubmed
11247302
uniprot
proteins
pubmed
1482349
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15677459
uniprot
proteins
pubmed
16314516
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7592716
uniprot
proteins
pubmed
8218408
uniprot
proteins
sequence_length
707
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Nucleus {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 637..660; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins