Defa4
entrez
13238
canonical
uniprot
P28311
canonical
genesymbol
Defa4
resolver
genesymbol_syn
Defcr4
resolver
uniprot
A3KPC1
resolver
uniprot
Q9QZL4
resolver
uniprot_entry
DEFA4_MOUSE
resolver
uniprot_sec
A3KPC1
resolver
uniprot_sec
Q9QZL4
resolver
amino_acid_sequence
MKTLVLLSALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSISFGGQEGSALHEKSLRGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR
uniprot
proteins
function
FUNCTION: Host-defense peptide that has antimicrobial activity (PubMed:7927786). Exhibits activity against Gram-negative E.coli (in vitro) (PubMed:7927786). Probably contributes to the antimicrobial barrier function of the small bowel mucosa (PubMed:7927786). {ECO:0000269|PubMed:7927786, ECO:0000303|PubMed:7927786}.
uniprot
proteins
mass_dalton
10272
uniprot
proteins
protein_family
Alpha-defensin family
uniprot
proteins
pubmed
10569786
uniprot
proteins
pubmed
1500431
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15595831
uniprot
proteins
pubmed
7927786
uniprot
proteins
pubmed
8188287
uniprot
proteins
sequence_length
92
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q01523}. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:10569786}.
uniprot
proteins