SERPINB10
entrez
5273
canonical
uniprot
P48595
canonical
ensembl
ENSG00000242550
resolver
ensp
ENSP00000238508
resolver
enst
ENST00000238508
resolver
genesymbol
SERPINB10
resolver
genesymbol_syn
PI10
resolver
hgnc
HGNC:8942
resolver
uniprot
B2RC45
resolver
uniprot
Q4VAX4
resolver
uniprot
Q4VAX7
resolver
uniprot_entry
B2RC45_HUMAN
resolver
uniprot_entry
SPB10_HUMAN
resolver
uniprot_sec
Q4VAX4
resolver
uniprot_sec
Q4VAX7
resolver
amino_acid_sequence
MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP
uniprot
proteins
function
FUNCTION: Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. {ECO:0000269|PubMed:10871600, ECO:0000269|PubMed:7592909}.
uniprot
proteins
mass_dalton
45403
uniprot
proteins
mutagenesis
MUTAGEN 74..77; /note="KKRK->AAAA: Abolishes nuclear localization."; MUTAGEN 395; /note="C->S: No effect on cell proliferation."; /evidence="ECO:0000269|PubMed:20433722
uniprot
proteins
protein_family
Ov-serpin subfamily
uniprot
proteins
protein_family
Serpin family
uniprot
proteins
pubmed
10196205
uniprot
proteins
pubmed
10871600
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20433722
uniprot
proteins
pubmed
7592909
uniprot
proteins
sequence_length
397
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=Mostly found in the nucleus.
uniprot
proteins