A2KF29
uniprot
A2KF29
canonical
amino_acid_sequence
MEKFHAQYEMLETIGQGGCAQVKLARHRLTGTHVAVKVIVKRECWFNPVMSEAELLMMTDHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIQNAGYLQEDEARPLFKQLLSAMNYCHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPGQNHNLFCEIYPFSTPEVLFNRPYDMRKIDVWGLGVVLYFMVTGKILFDTASVEKLRKQIVAEKCSVPCRLSVELQDLIRLLMTDIPELRPTVAEVMVHPWVTEGSGVLPDPCEEHIPLKPDPAIAKAMGFIGFQAQDIEDSLCQRKFNETMASYCLLKKQILKECDRPIRAQPMNPSVTPLSSLVDAPTFHLGLRRTETEPTGLRLSDNKEVPVCGNSTSKKRERSFSGPGVLSRPINTTPTMDQTHTRTWSGPCIYSNVCTIHPNSINESTEGHISTSAEDKPVHSRGWPRGIKGWTRKIGNAMRKLCCCIPSKETSHLGQRRVCPKI
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: While the main function of Smoks is to control sperm motility, the role of Smok-Tcr, with reduced kinase activity, is to counterbalance a signaling impairment caused by the distorter/sterility loci, giving t-sperm an advantage in reaching the oocytes. Transmission ratio distortion also called segregation distortion is the name given to the phenomenon above-mentioned. Being associated with the T-complex, it allows males heterozygous for a complete t-haplotype to preferentially transmit the t-haplotype chromosome. {ECO:0000269|PubMed:10647005}.
uniprot
proteins
mass_dalton
54619
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Smok subfamily
uniprot
proteins
protein_family
Tyr protein kinase family
uniprot
proteins
pubmed
10647005
uniprot
proteins
sequence_length
484
uniprot
proteins