CHIC2
entrez
26511
canonical
uniprot
Q9UKJ5
canonical
ensembl
ENSG00000109220
resolver
ensp
ENSP00000263921
resolver
ensp
ENSP00000421032
resolver
enst
ENST00000263921
resolver
enst
ENST00000510894
resolver
genesymbol
CHIC2
resolver
genesymbol_syn
BTL
resolver
hgnc
HGNC:1935
resolver
uniprot
B2R639
resolver
uniprot
H0Y8H1
resolver
uniprot_entry
CHIC2_HUMAN
resolver
uniprot_entry
H0Y8H1_HUMAN
resolver
uniprot_sec
B2R639
resolver
amino_acid_sequence
MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
uniprot
proteins
disease_involvement
DISEASE: Note=A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6. {ECO:0000269|PubMed:10477709}.
uniprot
proteins
mass_dalton
19254
uniprot
proteins
mutagenesis
MUTAGEN 88..95; /note="CGCLCCCC->SGSLSSSS: Loss of palmitoylation. Abolishes membrane association."; /evidence="ECO:0000269|PubMed:11257495
uniprot
proteins
post_translational_modification
PTM: Palmitoylation in the CHIC motif is required for membrane association. {ECO:0000269|PubMed:11257495}.
uniprot
proteins
protein_family
CHIC family
uniprot
proteins
pubmed
10477709
uniprot
proteins
pubmed
11257495
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
165
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11257495}. Cytoplasmic vesicle {ECO:0000269|PubMed:11257495}. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles.
uniprot
proteins