PRIMA1
entrez
145270
canonical
uniprot
Q86XR5
canonical
ensembl
ENSG00000175785
resolver
ensembl
ENSG00000274089
resolver
ensp
ENSP00000376848
resolver
ensp
ENSP00000577958
resolver
ensp
ENSP00000675438
resolver
genesymbol
PRIMA1
resolver
hgnc
HGNC:18319
resolver
uniprot
Q86XR6
resolver
uniprot_entry
PRIMA_HUMAN
resolver
uniprot_sec
Q86XR6
resolver
amino_acid_sequence
MLLRDLVLRRGCCWSSLLLHCALHPLWGFVQVTHGEPQKSCSKVTDSCRHVCQCRPPPPLPPPPPPPPPPRLLSAPAPNSTSCPTEESWWSGLVIIIAVCCASLVFLTVLVIICYKAIKRKPLRKDENGTSVAEYPMSASQSNKGVDVNNAVV
uniprot
proteins
function
FUNCTION: Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain. Also able to organize ACHE into tetramers (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
16689
uniprot
proteins
pubmed
11804574
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
19368807
uniprot
proteins
pubmed
22750213
uniprot
proteins
sequence_length
153
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction {ECO:0000250}. Synapse {ECO:0000250}. Note=In the brain, PRIMA linked to ACHE is found in membrane rafts. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 93..113; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins