Marchf4
entrez
381270
canonical
uniprot
Q80TE3
canonical
ensembl
ENSMUSG00000039372
resolver
ensp
ENSMUSP00000042803
resolver
ensp
ENSMUSP00000193582
resolver
enst
ENSMUST00000047786
resolver
genesymbol
Marchf4
resolver
genesymbol_syn
Kiaa1399
resolver
genesymbol_syn
March4
resolver
uniprot
Q4QQN4
resolver
uniprot_entry
MARH4_MOUSE
resolver
uniprot_sec
Q4QQN4
resolver
amino_acid_sequence
MLMPLGGLLWWWCCCCGWYSCGLCTPAPQMLRHQGLLKCRCRMLFNDLKVFLLRRPPPAPLPMHGDPQLPGVAANNNTLPALGAGGWAGWRGPREAVGRETPPLPPPPPLPPSGDDDWDGPATGPPASLLSSASSDEFCKEKTEDCYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQIAAAILGSLFLIASISWLIWSTFSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYRIFKRWQAVNQQWKVLNYDKTKDLEDQKSGGRTNLQTSSSAQANLPSAEEEAASPPAREEGPTRAASHPSGPVSQHHCAYTILHILSHLRPHDQRSTQGSGRELVMRVTTV
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000250|UniProtKB:Q9P2E8}.
uniprot
proteins
mass_dalton
45201
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
409
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 242..262; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 271..291; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins