Esrp2
entrez
307810
canonical
uniprot
B2RYJ8
canonical
ensembl
ENSRNOG00000023177
resolver
ensp
ENSRNOP00000026873
resolver
enst
ENSRNOT00000026873
resolver
genesymbol
Esrp2
resolver
genesymbol_syn
Rbm35b
resolver
uniprot
G3V8M2
resolver
uniprot_entry
ESRP2_RAT
resolver
uniprot_entry
G3V8M2_RAT
resolver
amino_acid_sequence
MTPPPPPPPPPGPDPAVDSSTDPCPEPQSLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLVRAEAAALSPQCREASGLSADSLARAESLDKVLQQFSQLVSGDVALLGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHVQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGPNGHLFSKPEVVKQKYETGPCKADVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFEDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPADVLDFLGPECPVTGGVDGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYAASPLLPTLTAPLLPIPFPLAGGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMMSVERALAAAQRCHKKVMKERYVEVVPCSTEEMSRVLMGGSLSRSGLSPPPCKLPCLSPPTYATFQASPALIPTETTALYPSSALLPAARVPAAATPLAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPPTALASTPTSMLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLAPDDYATLVPVGDPPRTVLQAPKEWVCL
uniprot
proteins
function
FUNCTION: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
77241
uniprot
proteins
protein_family
ESRP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
716
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins