Baz2b
entrez
407823
canonical
uniprot
A2AUY4
canonical
ensembl
ENSMUSG00000026987
resolver
ensp
ENSMUSP00000108169
resolver
ensp
ENSMUSP00000188359
resolver
ensp
ENSMUSP00000188360
resolver
ensp
ENSMUSP00000347370
resolver
genesymbol
Baz2b
resolver
uniprot
B9EKB5
resolver
uniprot
Q8C0K4
resolver
uniprot
Q8CFP4
resolver
uniprot_entry
BAZ2B_MOUSE
resolver
uniprot_sec
B9EKB5
resolver
uniprot_sec
Q8C0K4
resolver
uniprot_sec
Q8CFP4
resolver
amino_acid_sequence
MESGELLPSSPASSTTPTSSSAPSVASAVSKSSLSTGAASLSSTASPCVLEAGKSKIKVSPDSVSGAEWWRTTDGHSRAGTPFFPPLLGIPPLFAPPAQNHDSSFHSRTSGKSSRNGPEKGINGSVNGTSAASVLGVNASVVATPASSSMGQNQSTSSGGGTLKCHQEQNKSQPVDARADRIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEEEEEDQSVEESEDDDSDSETEAQHKSNNQVLLHGISDPKTDGQKATEKAQERRTHQPLPPVSESQTHPPFQSQQKQPQVLSQQLPFIFQSSQAKEESVTKHTSVIQSTGLVSNVKPLSLVNQAKKETYRKLVVPSPDVLKAGNKNTSEESSSLTSELRSKREQYKQTFPSQGKKQEMGKSLKKVIAALSNTKATSSSPAHPKLPLDNNHPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENVSSSTPFSSPVNLSTSGRRAPGSQTPALPSASPILHSSGKEKRVSNDATPLKAHHHPHPAAAAAALVEQFRGTDSDVPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSQSDSEGSEDDEEKDQEESDSDTEGEKPAVNLTQTSSSAKSPPSSLTAHSAPHLHIGSPPGSAPAALCSESQPPAFLGTSSSTLTSTPHSGTSKRRRVADDQELRIPLDYGWQRETRVRNFGGRLPGEVAYYAPCGKKLRQCPDMVKGMQWCLLKEEDVIPRIRAMDGRRGRPPNPDRPRAREESRMKRRKGRPPNVGSAEFLDNTDAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQMKIIKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRTKEKELRRQQAVLLKHQERERRRQHVMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPKEDMCLADQKPLPEWPRIPGLVLSGTTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEVLQIFMEAHCGQTELTESLKTKAFQAHTPAQKASILAFLVNELACSKSVVSEIDKNIEYMSNLRRDKWMVEGKLRKLRIIHAKKTGKRDASGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQADEDEEDEEDKDDKKGKKTDICEDEDEGDQTASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSMMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEKEKLKKAESLQIKEEVFETSAETLNCSIRDHCEQKDDPKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPESDVMTPPKVNVSTNGGPLSHQNSGKHPLGSVPSATTAQSPVGKTDASLFSSGSGSCGKFYSPLPNDQLLKTLTEKNRQWFSLLPKTPCDDTSLTHADLSTTLVTPQSQPPSKSPSPAPAALLGPSSVQSPPGLNPFALSPLQVKGGVSMMGLQFCGWPAGVLASNVPFTSPLPALGSGLGLPEGNGSSSFLTSSVASSKSDSPVPPAERPSSAQPVAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKTLLKVLHLRGIREKALQKQIQKHLDYITQACVRNKDVAIIELNENEDNQVTRDLVENWSVEEQAMELDLSILQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSLTKLFKEHDGELTGDEENSAHALARKSDNPLDIAVTRLADLERNIERRYLKSPLSTTIQIKLDNVGTVTVPAPAPSISGDGDGIEEDIAPGLRVWRRALAEARSAAQVALCIQQLQRSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACISKASGQSIKIKKIHVKGKKTNDSKKTKKGNVAGDTEDEDSASTSSSLKRGSKELKKRKMEETTSLNLSKAESTTSIKKPKKDESRDLALCSMILTEMETHEDSWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLNNGQYPNFETFALDVRLVFDNCETFNEDDSDIGRAGHSMRKYFEKKWTDTFKVS
uniprot
proteins
function
FUNCTION: Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair (By similarity). Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template (By similarity). The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex (By similarity). Chromatin reader protein, involved in positively modulating the rate of age-related behavioral deterioration (PubMed:32103178). Represses the expression of mitochondrial function-related genes, perhaps by occupying their promoter regions, working in concert with histone methyltransferase EHMT1 (PubMed:32103178). {ECO:0000250|UniProtKB:Q9UIF8, ECO:0000269|PubMed:32103178}.
uniprot
proteins
mass_dalton
234001
uniprot
proteins
protein_family
WAL family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
32103178
uniprot
proteins
sequence_length
2123
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00063}.
uniprot
proteins