Mydgf
entrez
28106
canonical
uniprot
Q9CPT4
canonical
ensembl
ENSMUSG00000019579
resolver
ensp
ENSMUSP00000019723
resolver
enst
ENSMUST00000019723
resolver
genesymbol
Mydgf
resolver
genesymbol_syn
D17Wsu104e
resolver
uniprot
A2RSI7
resolver
uniprot
Q3UG74
resolver
uniprot_entry
MYDGF_MOUSE
resolver
uniprot_sec
A2RSI7
resolver
uniprot_sec
Q3UG74
resolver
amino_acid_sequence
MAAPSGGFWTAVVLAAAALKLAAAVSEPTTVPFDVRPGGVVHSFSQDVGPGNKFTCTFTYASQGGTNEQWQMSLGTSEDSQHFTCTIWRPQGKSYLYFTQFKAELRGAEIEYAMAYSKAAFERESDVPLKSEEFEVTKTAVSHRPGAFKAELSKLVIVAKAARSEL
uniprot
proteins
function
FUNCTION: Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. {ECO:0000269|PubMed:25581518}.
uniprot
proteins
mass_dalton
17982
uniprot
proteins
protein_family
MYDGF family
uniprot
proteins
pubmed
11714798
uniprot
proteins
pubmed
12538725
uniprot
proteins
pubmed
15378209
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25581518
uniprot
proteins
sequence_length
166
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15378209, ECO:0000269|PubMed:25581518}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250|UniProtKB:Q969H8}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q969H8}. Golgi apparatus {ECO:0000250|UniProtKB:Q969H8}. Note=The C-terminal RTEL motif may provide retention in the endoplasmic reticulum. {ECO:0000250|UniProtKB:Q969H8}.
uniprot
proteins