Hsd3b6
entrez
15497
canonical
uniprot
O35469
canonical
ensembl
ENSMUSG00000027869
resolver
ensp
ENSMUSP00000029463
resolver
ensp
ENSMUSP00000129911
resolver
enst
ENSMUST00000029463
resolver
enst
ENSMUST00000170847
resolver
genesymbol
Hsd3b6
resolver
uniprot
Q3UQN7
resolver
uniprot
Q7TPU0
resolver
uniprot_entry
3BHS6_MOUSE
resolver
uniprot_entry
Q7TPU0_MOUSE
resolver
uniprot_sec
Q3UQN7
resolver
amino_acid_sequence
MPGWSCLVTGAGGFLGQRIVQLLMQEKDLEEIRVLDKFFRPETREQFFNLDTNIKVTVLEGDILDTQYLRKACQGISVVIHTAAVIDVTGVIPRQTILDVNLKGTQNLLEACIQASVPAFIFSSSVDVAGPNSYKEIILNGNEEEHHESIWSDPYPYSKKMAEKAVLAANGSMLKIGGTLHTCALRPMYIYGERSPFISNTIITALKNKNILGCTGKFSTANPVYVGNVAWAHILAARGLRDPKKSPNIQGEFYYISDDTPHQSYDDLNYTLSKEWGFCPDSSWSLPVPLLYWLAFMLETVSFLLSPIYRFIPPFNRHLVTLTGSTFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
uniprot
proteins
ec_number
1.1.1.-
uniprot
proteins
ec_number
1.1.1.145
uniprot
proteins
ec_number
5.3.3.1
uniprot
proteins
function
FUNCTION: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. May be involved in local production of progesterone.
uniprot
proteins
mass_dalton
41977
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; steroid biosynthesis.
uniprot
proteins
protein_family
3-beta-HSD family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9075693
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins