Gpr157
entrez
269604
canonical
uniprot
Q8C206
canonical
ensembl
ENSMUSG00000047875
resolver
ensp
ENSMUSP00000092020
resolver
enst
ENSMUST00000094451
resolver
genesymbol
Gpr157
resolver
uniprot
Q148S2
resolver
uniprot
Q8C224
resolver
uniprot_entry
GP157_MOUSE
resolver
uniprot_entry
Q148S2_MOUSE
resolver
uniprot_sec
Q8C224
resolver
amino_acid_sequence
MPSPAPPTELLPWERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQDFAGTSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVRTTRGPSTDHLIWAFHLISWGVPLAITVAAVSLKKIGYDASDVSVGWCWINLEAEDRVLWMLLTGKLWEMLAYILLPLLYLLVRKHINRAHQALSEYRPICEGRQLQRGSSTSTADKKLVLIPLIFICLRVWSTVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCPRPSTQSPPGAPTPPKIGESQESRRTPEVPST
uniprot
proteins
function
FUNCTION: Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs) (PubMed:27142930). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger (PubMed:27142930). {ECO:0000269|PubMed:27142930}.
uniprot
proteins
mass_dalton
36344
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
27142930
uniprot
proteins
sequence_length
330
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium membrane {ECO:0000269|PubMed:27142930}; Multi-pass membrane protein {ECO:0000255}. Note=Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid. {ECO:0000269|PubMed:27142930}.
uniprot
proteins
transmembrane_region
TRANSMEM 16..36; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 49..69; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 120..140; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 228..248; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 260..280; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins