Brpf1
entrez
78783
canonical
uniprot
B2RRD7
canonical
ensembl
ENSMUSG00000001632
resolver
ensp
ENSMUSP00000108742
resolver
ensp
ENSMUSP00000108744
resolver
ensp
ENSMUSP00000108746
resolver
ensp
ENSMUSP00000108747
resolver
ensp
ENSMUSP00000144804
resolver
ensp
ENSMUSP00000144820
resolver
ensp
ENSMUSP00000145093
resolver
ensp
ENSMUSP00000244823
resolver
ensp
ENSMUSP00000244824
resolver
ensp
ENSMUSP00000244825
resolver
ensp
ENSMUSP00000244826
resolver
ensp
ENSMUSP00000336327
resolver
enst
ENSMUST00000113117
resolver
enst
ENSMUST00000113119
resolver
enst
ENSMUST00000113121
resolver
enst
ENSMUST00000113122
resolver
enst
ENSMUST00000203577
resolver
enst
ENSMUST00000204198
resolver
enst
ENSMUST00000204626
resolver
genesymbol
Brpf1
resolver
uniprot
A0A0N4SUS4
resolver
uniprot
A0A0N4SUT9
resolver
uniprot
A0A0N4SVG7
resolver
uniprot
E9PXP1
resolver
uniprot
F7ADM6
resolver
uniprot
F7ADN4
resolver
uniprot
Q3U109
resolver
uniprot
Q80XK2
resolver
uniprot
Q8C905
resolver
uniprot
Q9CTY1
resolver
uniprot_entry
A0A0N4SUS4_MOUSE
resolver
uniprot_entry
A0A0N4SUT9_MOUSE
resolver
uniprot_entry
A0A0N4SVG7_MOUSE
resolver
uniprot_entry
BRPF1_MOUSE
resolver
uniprot_entry
E9PXP1_MOUSE
resolver
uniprot_entry
F7ADM6_MOUSE
resolver
uniprot_entry
F7ADN4_MOUSE
resolver
uniprot_entry
Q3U109_MOUSE
resolver
uniprot_entry
Q80XK2_MOUSE
resolver
uniprot_entry
Q8C905_MOUSE
resolver
uniprot_entry
Q9CTY1_MOUSE
resolver
amino_acid_sequence
MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDSPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHSAPASAAPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEEEDEEEDEGKSWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCEQVGRDSDDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKIQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHNLAGDEVSHHTEDVEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPSGRGNLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMGSLRQRKRGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSSGNQPVKKSFLVYRNDCNLPRSSSDSESSSSSSSSAASDRTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD
uniprot
proteins
function
FUNCTION: Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (By similarity). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac) (By similarity). Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation (PubMed:27939640). Positively regulates the transcription of RUNX1 and RUNX2 (By similarity). {ECO:0000250|UniProtKB:P55201, ECO:0000269|PubMed:27939640}.
uniprot
proteins
mass_dalton
137310
uniprot
proteins
post_translational_modification
PTM: Acetylated by KAT6A. {ECO:0000250|UniProtKB:P55201}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24646517
uniprot
proteins
pubmed
25773539
uniprot
proteins
pubmed
27939640
uniprot
proteins
sequence_length
1212
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P55201}. Chromosome {ECO:0000250|UniProtKB:P55201}. Cytoplasm {ECO:0000250|UniProtKB:P55201}. Note=Localization to the nucleus depends on KAT6A, ING5 and MEAF6. Localizes to transcription start sites. {ECO:0000250|UniProtKB:P55201}.
uniprot
proteins