Apobec1
entrez
25383
canonical
uniprot
P38483
canonical
ensembl
ENSRNOG00000015411
resolver
ensp
ENSRNOP00000020735
resolver
ensp
ENSRNOP00000078194
resolver
enst
ENSRNOT00000020735
resolver
genesymbol
Apobec1
resolver
uniprot_entry
ABEC1_RAT
resolver
amino_acid_sequence
MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSIWRHTSQNTNKHVEVNFIEKFTTERYFCPNTRCSITWFLSWSPCGECSRAITEFLSRYPHVTLFIYIARLYHHADPRNRQGLRDLISSGVTIQIMTEQESGYCWRNFVNYSPSNEAHWPRYPHLWVRLYVLELYCIILGLPPCLNILRRKQPQLTFFTIALQSCHYQRLPPHILWATGLK
uniprot
proteins
ec_number
3.5.4.-
uniprot
proteins
ec_number
3.5.4.36
uniprot
proteins
function
FUNCTION: Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs. Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA (PubMed:8511591). Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA (By similarity). May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (By similarity). {ECO:0000250|UniProtKB:P41238, ECO:0000250|UniProtKB:P51908, ECO:0000269|PubMed:8511591}.
uniprot
proteins
mass_dalton
27274
uniprot
proteins
protein_family
Cytidine and deoxycytidylate deaminase family
uniprot
proteins
pubmed
10669759
uniprot
proteins
pubmed
11134005
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8511591
uniprot
proteins
sequence_length
229
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P41238}. Nucleus {ECO:0000250|UniProtKB:P41238}.
uniprot
proteins