Slc24a4
entrez
238384
canonical
uniprot
Q8CGQ8
canonical
ensembl
ENSMUSG00000041771
resolver
ensp
ENSMUSP00000078030
resolver
ensp
ENSMUSP00000125012
resolver
ensp
ENSMUSP00000157352
resolver
enst
ENSMUST00000161325
resolver
enst
ENSMUST00000235018
resolver
genesymbol
Slc24a4
resolver
genesymbol_syn
Nckx4
resolver
uniprot
A0A0R4J0Z4
resolver
uniprot
F7B0S9
resolver
uniprot
Q8BLL5
resolver
uniprot
Q8BLL7
resolver
uniprot_entry
A0A0R4J0Z4_MOUSE
resolver
uniprot_entry
F7B0S9_MOUSE
resolver
uniprot_entry
NCKX4_MOUSE
resolver
uniprot_sec
Q8BLL5
resolver
uniprot_sec
Q8BLL7
resolver
amino_acid_sequence
MALRGLIRQSKVRRRREMLPQQVGFVCAVLALVCCASGLFGSLGHKTASAGKHVLLDTWRNRKLMAPINGTPLAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSYDDPSVPLLGQVKEKPPYGKTPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPPPQPPPPEPESVETVFLSPFSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMCREDD
uniprot
proteins
function
FUNCTION: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (PubMed:22057188). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived (PubMed:22057188). May play a role in calcium transport during amelogenesis (PubMed:23375655). {ECO:0000269|PubMed:22057188, ECO:0000269|PubMed:23375655}.
uniprot
proteins
mass_dalton
68974
uniprot
proteins
protein_family
Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family
uniprot
proteins
protein_family
SLC24A subfamily
uniprot
proteins
pubmed
12379639
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
22057188
uniprot
proteins
pubmed
22677781
uniprot
proteins
pubmed
23375655
uniprot
proteins
pubmed
24621671
uniprot
proteins
pubmed
26247047
uniprot
proteins
sequence_length
622
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24621671, ECO:0000269|PubMed:26247047}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:24621671, ECO:0000269|PubMed:26247047}.
uniprot
proteins
transmembrane_region
TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 143..163; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 173..193; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 458..478; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 480..500; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 527..547; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 558..578; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 587..607; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins