Tmem8b
entrez
242409
canonical
uniprot
B1AWJ5
canonical
ensembl
ENSMUSG00000078716
resolver
ensp
ENSMUSP00000103496
resolver
ensp
ENSMUSP00000103497
resolver
ensp
ENSMUSP00000103498
resolver
ensp
ENSMUSP00000129760
resolver
ensp
ENSMUSP00000190677
resolver
enst
ENSMUST00000107864
resolver
enst
ENSMUST00000107865
resolver
enst
ENSMUST00000107866
resolver
enst
ENSMUST00000167153
resolver
genesymbol
Tmem8b
resolver
uniprot
B1AWJ4
resolver
uniprot
B9EJV2
resolver
uniprot_entry
B1AWJ4_MOUSE
resolver
uniprot_entry
TMM8B_MOUSE
resolver
uniprot_sec
B9EJV2
resolver
amino_acid_sequence
MNMPQSLGTQPLPPEPPSLGTPIEGSGAIAPTEHCWPVRPTLRNELDTFSVHFYIFFGPSVALPPERPAVFALRLLPVLDSGGVLSLELQLNASSLRQENVTVFGCLTHEVPLSLGDAAVTCSKESLAGFLLSVSATSRVARLRIPFPQTGTWFLTLRSLCGVGPRFVRCRNATAEVRLRTFLSPCVDDCGPYGQCKLLRTHNYLYAACECKAGWRGWGCTDSADALTYGFQLLSTLLLCLSNLMFLPPVVLAIRSRYVLEAAVYTFTMFFSTFYHACDQPGIVVFCIMDYDVLQFCDFLGSLMSVWVTVIAMARLQPVIKQVLYLLGAMLLSMALQLDRHGLWNLLGPSLFALGILATAWTVRSVRRRHCYPPTWRRWLFYLCPGSLIAGSAVLLYAFVETRDNYFYIHSIWHMLIAGSVGFLLPPRAKTDRRVPSGARARGCGYQLCINEQEELGLVGPGGTTVSSICVS
uniprot
proteins
function
FUNCTION: May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
52114
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
TMEM8 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
472
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:A6NDV4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:A6NDV4}. Cytoplasm {ECO:0000250|UniProtKB:A6NDV4}. Nucleus {ECO:0000250|UniProtKB:A6NDV4}. Mitochondrion {ECO:0000250|UniProtKB:A6NDV4}. Endoplasmic reticulum {ECO:0000250|UniProtKB:A6NDV4}. Note=Also detected in mitochondrion and endoplasmic reticulum. {ECO:0000250|UniProtKB:A6NDV4}.
uniprot
proteins
transmembrane_region
TRANSMEM 234..254; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 258..277; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 293..313; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 316..336; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 343..363; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 380..400; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 406..426; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins