Prrg2
entrez
65116
canonical
uniprot
Q8R182
canonical
ensembl
ENSMUSG00000007837
resolver
ensp
ENSMUSP00000007981
resolver
ensp
ENSMUSP00000147844
resolver
ensp
ENSMUSP00000148014
resolver
ensp
ENSMUSP00000202790
resolver
enst
ENSMUST00000007981
resolver
enst
ENSMUST00000210690
resolver
genesymbol
Prrg2
resolver
genesymbol_syn
N4wbp1
resolver
uniprot
Q9EQI2
resolver
uniprot_entry
TMG2_MOUSE
resolver
uniprot_sec
Q9EQI2
resolver
amino_acid_sequence
MRGRPSLLLVYMGLATCLDTSPHREQNQVLDIFLDAPEAQSFLVGRRRFPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYTYNGKGGRGRVDVAGLAVGLTSGILLIVLAGLGAFWYLHYRRRRLRGQESCLQETGLIIPLSPQTPQSPPLPPGLPTYEQALAASGVHDAPPPPYSSLRRPH
uniprot
proteins
function
FUNCTION: Vitamin K-dependent protein that is essential for calcium homeostasis and haemostasis. {ECO:0000250|UniProtKB:O14669}.
uniprot
proteins
mass_dalton
22369
uniprot
proteins
mutagenesis
MUTAGEN 191; /note="Y->A: No effect on interaction with NEDD4."; /evidence="ECO:0000269|PubMed:11042109
uniprot
proteins
post_translational_modification
PTM: Carboxylated by vitamin K-dependent GGCX to form gamma-carboxyglutamate; these residues are essential for the binding of calcium (By similarity). {ECO:0000250|UniProtKB:O14669}.
uniprot
proteins
pubmed
11042109
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O14669}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 112..132; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins