EECP
entrez
124220
canonical
uniprot
Q96DA0
canonical
ensembl
ENSG00000162078
resolver
ensembl
ENSG00000283056
resolver
ensp
ENSP00000371715
resolver
ensp
ENSP00000461740
resolver
ensp
ENSP00000489035
resolver
ensp
ENSP00000489251
resolver
ensp
ENSP00000572316
resolver
enst
ENST00000382280
resolver
enst
ENST00000572863
resolver
enst
ENST00000634500
resolver
enst
ENST00000634906
resolver
enst
ENST00000902257
resolver
genesymbol
EECP
resolver
genesymbol
ZG16B
resolver
genesymbol_syn
PAUF
resolver
hgnc
HGNC:30456
resolver
uniprot
A0A0C4DGN4
resolver
uniprot
A6NIY1
resolver
uniprot
B2R4F6
resolver
uniprot
C3PTT6
resolver
uniprot
G8H6I3
resolver
uniprot
Q6UW28
resolver
uniprot_entry
A0A0C4DGN4_HUMAN
resolver
uniprot_entry
G8H6I3_HUMAN
resolver
uniprot_entry
PAUF_HUMAN
resolver
uniprot_sec
A6NIY1
resolver
uniprot_sec
B2R4F6
resolver
uniprot_sec
C3PTT6
resolver
uniprot_sec
Q6UW28
resolver
amino_acid_sequence
MLLLLTLALLGGPTWAGKMYGPGGGKYFSTTEDYDHEITGLRVSVGLLLVKSVQVKLGDSWDVKLGALGGNTQEVTLQPGEYITKVFVAFQAFLRGMVMYTSKDRYFYFGKLDGQISSAYPSQEGQVLVGIYGQYQLLGIKSIGFEWNYPLEEPTTEPPVNLTYSANSPVGR
uniprot
proteins
function
FUNCTION: Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism (PubMed:37216558). Plays an important role in pancreatic tumor progression and metastasis (PubMed:19302292, PubMed:36232715). Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway (PubMed:36232715). {ECO:0000269|PubMed:19302292, ECO:0000269|PubMed:36232715, ECO:0000269|PubMed:37216558}.
uniprot
proteins
mass_dalton
18879
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:19302292}.
uniprot
proteins
protein_family
Jacalin lectin family
uniprot
proteins
pubmed
11678034
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
19302292
uniprot
proteins
pubmed
21110947
uniprot
proteins
pubmed
33207190
uniprot
proteins
pubmed
36232715
uniprot
proteins
pubmed
37216558
uniprot
proteins
sequence_length
172
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19302292, ECO:0000269|PubMed:33207190}. Cytoplasm {ECO:0000269|PubMed:19302292}. Cell membrane {ECO:0000269|PubMed:36232715}. Apicolateral cell membrane {ECO:0000269|PubMed:19302292}. Note=Co-localizes with TLR4 at the cell membrane of pancreatic cancer cells. {ECO:0000269|PubMed:36232715}.
uniprot
proteins