Chlsn
entrez
498154
canonical
uniprot
Q5I0E3
canonical
ensembl
ENSRNOG00000001289
resolver
ensp
ENSRNOP00000092701
resolver
enst
ENSRNOT00000101891
resolver
genesymbol
Chlsn
resolver
genesymbol_syn
LOC498154
resolver
uniprot
A0A8I6AIG4
resolver
uniprot_entry
A0A8I6AIG4_RAT
resolver
uniprot_entry
CHOLN_RAT
resolver
amino_acid_sequence
MVKQKRKGLERTAKESKKQKITPAEETPRASEARPGKEAASPVVQEASPELSPEERRVLERKLKKERKKEEKKRLREAGIATAQTAKVQTPPAKPSAAVLALEYLQGWAEKQESWRFQKTRQTWLLLHMYDEDKVPEQHFSTLLDYLEGLRGSARELTVQKAETLMQELDGTDPKARSLGKMQRLRQVLQLLS
uniprot
proteins
function
FUNCTION: Hormone secreted from the intestine in response to cholesterol, where it acts to inhibit cholesterol synthesis in the liver and VLDL secretion,leading to a reduction in circulating cholesterol levels. Acts through binding to its receptor, GPR146. {ECO:0000250|UniProtKB:Q9CXL3}.
uniprot
proteins
mass_dalton
22126
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
193
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q9CXL3}. Note=Secretion is induced by feeding and cholesterol absorption. {ECO:0000250|UniProtKB:Q9CXL3}.
uniprot
proteins