TMEM186
entrez
25880
canonical
uniprot
Q96B77
canonical
ensembl
ENSG00000184857
resolver
ensp
ENSP00000331640
resolver
enst
ENST00000333050
resolver
genesymbol
TMEM186
resolver
genesymbol_syn
C16orf51
resolver
hgnc
HGNC:24530
resolver
uniprot
B2RAY0
resolver
uniprot
Q9Y4T4
resolver
uniprot_entry
TM186_HUMAN
resolver
uniprot_sec
B2RAY0
resolver
uniprot_sec
Q9Y4T4
resolver
amino_acid_sequence
MAALLRAVRRFRGKAVWERPLHGLWCCSGQEDPKRWVGSSSPISKEKLPNAETEKFWMFYRFDAIRTFGFLSRLKLAQTALTVVALPPGYYLYSQGLLTLNTVCLMSGISGFALTMLCWMSYFLRRLVGILYLNESGTMLRVAHLNFWGWRQDTYCPMADVIPLTETKDRPQEMFVRIQRYSGKQTFYVTLRYGRILDRERFTQVFGVHQMLK
uniprot
proteins
function
FUNCTION: As part of the MCIA complex, required for efficient assembly of the mitochondrial complex I. {ECO:0000269|PubMed:32320651}.
uniprot
proteins
mass_dalton
24893
uniprot
proteins
protein_family
TMEM186 family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
32275929
uniprot
proteins
pubmed
32320651
uniprot
proteins
sequence_length
213
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:32320651, ECO:0000305|PubMed:32275929}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 80..100; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins