Kcng3
entrez
225030
canonical
uniprot
P59053
canonical
ensembl
ENSMUSG00000045053
resolver
ensp
ENSMUSP00000054910
resolver
ensp
ENSMUSP00000157121
resolver
genesymbol
Kcng3
resolver
uniprot_entry
KCNG3_MOUSE
resolver
amino_acid_sequence
MTFGRGGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTHTFHAADELGREQPRPAGPEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRAAVADNRSLDDRSRYSASPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMAMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFASIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSAEFLN
uniprot
proteins
function
FUNCTION: Regulatory subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1, modulates the kinetics parameters of the heterotetrameric channel namely the inactivation and deactivation rate. Potassium channel subunit that does not form functional channels by itself. Reduces the deactivation rate. Moderately acceleratee activation. {ECO:0000250|UniProtKB:Q8TAE7}.
uniprot
proteins
mass_dalton
49247
uniprot
proteins
protein_family
G (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv6.3/KCNG3 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
sequence_length
433
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8TAE7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8TAE7}. Cytoplasm {ECO:0000250|UniProtKB:Q8TAE7}. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Colocalizes with KCNB1 at the plasma membrane. Retains in the endoplasmic reticulum in the absence of KCNB1. {ECO:0000250|UniProtKB:Q8TAE7}.
uniprot
proteins
transmembrane_region
TRANSMEM 166..187; /note="Helical; Name=Segment S1"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 218..239; /note="Helical; Name=Segment S2"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 251..271; /note="Helical; Name=Segment S3"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 282..302; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 318..339; /note="Helical; Name=Segment S5"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 385..413; /note="Helical; Name=Segment S6"; /evidence="ECO:0000250|UniProtKB:P63142
uniprot
proteins