MTX1
entrez
4580
canonical
uniprot
Q13505
canonical
ensembl
ENSG00000173171
resolver
ensp
ENSP00000317106
resolver
ensp
ENSP00000357360
resolver
genesymbol
MTX1
resolver
genesymbol_syn
MTX
resolver
genesymbol_syn
MTXN
resolver
hgnc
HGNC:7504
resolver
uniprot
A0A0A0MRK6
resolver
uniprot
B1AVR9
resolver
uniprot
B1AVS0
resolver
uniprot
B2R9P4
resolver
uniprot
Q9BUU3
resolver
uniprot_entry
MTX1_HUMAN
resolver
uniprot_sec
A0A0A0MRK6
resolver
uniprot_sec
B1AVR9
resolver
uniprot_sec
B1AVS0
resolver
uniprot_sec
B2R9P4
resolver
uniprot_sec
Q9BUU3
resolver
amino_acid_sequence
MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRRRDSPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE
uniprot
proteins
function
FUNCTION: Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
51463
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. {ECO:0000269|PubMed:25621951}.
uniprot
proteins
protein_family
Metaxin family
uniprot
proteins
pubmed
10381257
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22114354
uniprot
proteins
pubmed
25621951
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
25997101
uniprot
proteins
pubmed
31644573
uniprot
proteins
pubmed
8660965
uniprot
proteins
pubmed
9331372
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Mitochondrion outer membrane {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 421..441; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins