Lemd3
entrez
380664
canonical
uniprot
Q9WU40
canonical
ensembl
ENSMUSG00000048661
resolver
ensp
ENSMUSP00000113103
resolver
enst
ENSMUST00000119944
resolver
genesymbol
Lemd3
resolver
genesymbol_syn
Man1
resolver
uniprot
E9QP59
resolver
uniprot
Q0VGU6
resolver
uniprot
Q3USB5
resolver
uniprot_entry
E9QP59_MOUSE
resolver
uniprot_entry
MAN1_MOUSE
resolver
uniprot_sec
Q0VGU6
resolver
uniprot_sec
Q3USB5
resolver
amino_acid_sequence
MAAATAAAAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQQQQQQQQQHRAGGRGNKTRNSNNNNTATAMGGRPGSGDLAYLRSPAGLGRLSASAAESPVAGGSGGAAAVPAAGSKVLLGFSSDESDVEASPREQAGGGGGGGARRDRAALQYRGLRAPPAPPAAGEVTGGHPGERRKPHSWWGARRPAGPEPQPPAAGSDGAAEDADEELADGEDRDPEAEEPLWASRAVNGSRLLPYSSCREHYSDSEEEEEEGEEDGDVAPARQVLKDDSLARHRPRRSHSKPFSALTAKSGGSRQETSVQGGGALAMNDRAAAAGSLDRSRNLEEAAAEPGGGGGGGCGCDPVDSIPRYRAGAKKLAPLLSPPSPDGDSTLESPTGPLLKTNNHIGGGAFGVDSPGLYANSLPPGATAAAAPGTLRINHANHTGSNHTYLKTAYGKPKLCEPEEELLQQFKREEVSPTGSFSAHYLSMFLLTAACLFFLILGLTYLGMRGTGVPEDGGLIKNPFDETFGKIQESEKNLLMSTLYKLHDRLAQIAGDHECGSSSQRMLSVQEAAAYLKNLGPEYEDVFNTSLLWIFKNGKDVGIRCVGYGPEEDLTNITDVQFLQSTRPQMPFWCRFRRAFITVTHRLLLLCLGVVLVCVALRYMRYRWTKEEEETRQMYDMVVKIIDVLRSHNEACQETKDLQPYMPLPHVRDSLIQPQDRKKMKKVWDRAVDFLAANESRVRTETRRVGGADFLVWRWIQPSASCDKTLVIPSKVWQGQAFHLDRRNSPPNSLTPCLKIRNMFDPVMEIGDHWHLAIQEAILEKCSDNDGIVHIAVDRNSREGCVYVKCLSPEYAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTCNTPLKPANKHMNSLSHLRLRTGLANSQGSS
uniprot
proteins
function
FUNCTION: Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
100307
uniprot
proteins
pubmed
10671519
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
921
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus inner membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 486..506; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 637..657; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins