CXCL6
entrez
6372
canonical
uniprot
P80162
canonical
ensembl
ENSG00000124875
resolver
ensp
ENSP00000226317
resolver
enst
ENST00000226317
resolver
genesymbol
CXCL6
resolver
genesymbol_syn
GCP2
resolver
genesymbol_syn
SCYB6
resolver
hgnc
HGNC:10643
resolver
uniprot
B2R4X3
resolver
uniprot
Q4W5D4
resolver
uniprot_entry
CXCL6_HUMAN
resolver
uniprot_sec
B2R4X3
resolver
uniprot_sec
Q4W5D4
resolver
amino_acid_sequence
MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN
uniprot
proteins
function
FUNCTION: Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7). {ECO:0000269|PubMed:18443119, ECO:0000269|PubMed:8399143, ECO:0000269|PubMed:8423327, ECO:0000269|PubMed:9057843}.
uniprot
proteins
mass_dalton
11897
uniprot
proteins
protein_family
Intercrine alpha (chemokine CxC) family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
18443119
uniprot
proteins
pubmed
8399143
uniprot
proteins
pubmed
8423327
uniprot
proteins
pubmed
9057843
uniprot
proteins
pubmed
9164944
uniprot
proteins
sequence_length
114
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins