Gpr87
entrez
84111
canonical
uniprot
Q99MT7
canonical
ensembl
ENSMUSG00000051431
resolver
ensp
ENSMUSP00000143683
resolver
enst
ENSMUST00000200095
resolver
genesymbol
Gpr87
resolver
uniprot
Q8C4Y7
resolver
uniprot_entry
GPR87_MOUSE
resolver
uniprot_sec
Q8C4Y7
resolver
amino_acid_sequence
MGLNLTLTKLPGNELYSQASHTANSTSEGHGKNSTLHNKFDTIILPVLYLVIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVRDAGFGPWYFEFILCRYTSVLFYANMYTSIVFLGLISVDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAILSLPNIILTNGQPTKENIHDCMKLKSPLGAKWHMAVTYVDSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSNLDRLLDESAHKILYYCKEMTLFLSACNVCLDPIIYFFMCKSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV
uniprot
proteins
function
FUNCTION: Receptor for lysophosphatidic acid (LPA) (PubMed:17905198). Necessary for p53/TP53-dependent survival in response to DNA damage (By similarity). Promotes the Hippo-YAP signaling pathway and thereby modulates glycolysis and oxidative stress production by the regulation of hexokinase-2/HK2 (By similarity). {ECO:0000250|UniProtKB:Q9BY21, ECO:0000269|PubMed:17905198}.
uniprot
proteins
mass_dalton
41414
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11273702
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17905198
uniprot
proteins
pubmed
35843477
uniprot
proteins
sequence_length
358
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 48..68; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 160..180; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 257..277; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 298..318; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins