BLCAP
entrez
10904
canonical
uniprot
P62952
canonical
ensembl
ENSG00000166619
resolver
ensp
ENSP00000362637
resolver
ensp
ENSP00000380320
resolver
ensp
ENSP00000380323
resolver
ensp
ENSP00000380324
resolver
ensp
ENSP00000380326
resolver
ensp
ENSP00000397172
resolver
ensp
ENSP00000414973
resolver
ensp
ENSP00000564321
resolver
ensp
ENSP00000564322
resolver
ensp
ENSP00000564323
resolver
ensp
ENSP00000564324
resolver
ensp
ENSP00000564325
resolver
ensp
ENSP00000564326
resolver
ensp
ENSP00000587276
resolver
ensp
ENSP00000587277
resolver
ensp
ENSP00000587278
resolver
ensp
ENSP00000587279
resolver
ensp
ENSP00000633626
resolver
ensp
ENSP00000633627
resolver
ensp
ENSP00000633628
resolver
ensp
ENSP00000633629
resolver
ensp
ENSP00000633630
resolver
ensp
ENSP00000633631
resolver
enst
ENST00000373537
resolver
enst
ENST00000397131
resolver
enst
ENST00000397134
resolver
enst
ENST00000397135
resolver
enst
ENST00000397137
resolver
enst
ENST00000414542
resolver
enst
ENST00000432507
resolver
enst
ENST00000894262
resolver
enst
ENST00000894263
resolver
enst
ENST00000894264
resolver
enst
ENST00000894265
resolver
enst
ENST00000894266
resolver
enst
ENST00000894267
resolver
enst
ENST00000917217
resolver
enst
ENST00000917218
resolver
enst
ENST00000917219
resolver
enst
ENST00000917220
resolver
enst
ENST00000963567
resolver
enst
ENST00000963568
resolver
enst
ENST00000963569
resolver
enst
ENST00000963570
resolver
enst
ENST00000963571
resolver
enst
ENST00000963572
resolver
genesymbol
BLCAP
resolver
genesymbol_syn
BC10
resolver
hgnc
HGNC:1055
resolver
uniprot
A2A2K7
resolver
uniprot
O60629
resolver
uniprot
Q9D3B5
resolver
uniprot_entry
BLCAP_HUMAN
resolver
uniprot_sec
A2A2K7
resolver
uniprot_sec
O60629
resolver
uniprot_sec
Q9D3B5
resolver
amino_acid_sequence
MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCTICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT
uniprot
proteins
function
FUNCTION: Acts as a tumor suppressor; induces growth arrest at G(1)/S checkpoint and apoptosis via RB1-dependent and p53/TP53- and NF-kappa-B-independent mechanisms (PubMed:16675915, PubMed:17031575, PubMed:21844121, PubMed:26986503). Modulates expression of genes involved in the regulation of proliferation, cell cycle and apoptosis (PubMed:17031575, PubMed:21844121, PubMed:26986503). {ECO:0000269|PubMed:16675915, ECO:0000269|PubMed:17031575, ECO:0000269|PubMed:21844121, ECO:0000269|PubMed:26986503}.
uniprot
proteins
mass_dalton
9876
uniprot
proteins
mutagenesis
MUTAGEN 16..19; /note="PLNP->ALNA: No significant effect on activity."; /evidence="ECO:0000269|PubMed:26986503"; MUTAGEN 74; /note="P->A: Reduces activity."; /evidence="ECO:0000269|PubMed:26986503"; MUTAGEN 78; /note="S->A: No significant effect on activity."; /evidence="ECO:0000269|PubMed:26986503
uniprot
proteins
protein_family
BLCAP family
uniprot
proteins
pubmed
10197429
uniprot
proteins
pubmed
11072240
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16675915
uniprot
proteins
pubmed
17031575
uniprot
proteins
pubmed
19783793
uniprot
proteins
pubmed
19908260
uniprot
proteins
pubmed
21844121
uniprot
proteins
pubmed
22969892
uniprot
proteins
pubmed
26986503
uniprot
proteins
pubmed
29190807
uniprot
proteins
sequence_length
87
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19783793, ECO:0000269|PubMed:22969892, ECO:0000269|PubMed:29190807}. Nucleus {ECO:0000269|PubMed:19783793, ECO:0000269|PubMed:29190807}. Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins