Cacnb2
entrez
116600
canonical
uniprot
Q8VGC3
canonical
ensembl
ENSRNOG00000018378
resolver
ensp
ENSRNOP00000037354
resolver
ensp
ENSRNOP00000063474
resolver
ensp
ENSRNOP00000078040
resolver
ensp
ENSRNOP00000088262
resolver
ensp
ENSRNOP00000093071
resolver
ensp
ENSRNOP00000093724
resolver
enst
ENSRNOT00000031542
resolver
enst
ENSRNOT00000066826
resolver
enst
ENSRNOT00000101858
resolver
enst
ENSRNOT00000103017
resolver
enst
ENSRNOT00000118698
resolver
genesymbol
Cacnb2
resolver
genesymbol_syn
Cacnlb2
resolver
uniprot
A0A0G2JSZ0
resolver
uniprot
A0A678X7M6
resolver
uniprot
A0A8I6A7Q8
resolver
uniprot
A0A8I6GKE9
resolver
uniprot
D3ZWK0
resolver
uniprot
Q811Q6
resolver
uniprot
Q811Q7
resolver
uniprot
Q91ZJ8
resolver
uniprot
Q9QUU7
resolver
uniprot_entry
A0A0G2JSZ0_RAT
resolver
uniprot_entry
A0A678X7M6_RAT
resolver
uniprot_entry
A0A8I6A7Q8_RAT
resolver
uniprot_entry
A0A8I6GKE9_RAT
resolver
uniprot_entry
CACB2_RAT
resolver
uniprot_entry
D3ZWK0_RAT
resolver
uniprot_sec
Q811Q6
resolver
uniprot_sec
Q811Q7
resolver
uniprot_sec
Q91ZJ8
resolver
uniprot_sec
Q9QUU7
resolver
amino_acid_sequence
MVQSDTSKSPPIAAVAQESQMELLESAAPAGALGAQSYGKGARRKNRFKGSDDSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRTLATSTLPLSPTLASNSQGSQGDQRTDRSAPRSASQAEEEPCLEPVKKSQHRSSSATHQNHRSGTGRGLSRQETFDSETQESRDSAYVEPKEDYSHEHVDRYVPHREHNHREESHSSNGHRHREPRHRTRDMGRDQDHNECSKQRSRHKSKDRYCDKEGEVISKRRSEAGEWNRDVYIRQ
uniprot
proteins
function
FUNCTION: Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current (PubMed:12042350, PubMed:1370480). Plays a role in shifting voltage dependencies of activation and inactivation of the channel (PubMed:12042350, PubMed:1370480). May modulate G protein inhibition (PubMed:11604404, PubMed:12042350, PubMed:1370480). May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force (By similarity). Involved in membrane targeting of the alpha-1 subunit CACNA1C (By similarity). {ECO:0000250|UniProtKB:Q08289, ECO:0000250|UniProtKB:Q8CC27, ECO:0000269|PubMed:11604404, ECO:0000269|PubMed:12042350, ECO:0000269|PubMed:1370480}.
uniprot
proteins
mass_dalton
73226
uniprot
proteins
post_translational_modification
PTM: Regulated through phosphorylation at Thr-549 by CaMK2D. {ECO:0000269|PubMed:20194790}.
uniprot
proteins
protein_family
Calcium channel beta subunit family
uniprot
proteins
pubmed
11604404
uniprot
proteins
pubmed
12042350
uniprot
proteins
pubmed
1370480
uniprot
proteins
pubmed
15141227
uniprot
proteins
pubmed
20194790
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
24751537
uniprot
proteins
pubmed
26680202
uniprot
proteins
sequence_length
655
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane, sarcolemma {ECO:0000269|PubMed:12042350}; Peripheral membrane protein {ECO:0000269|PubMed:12042350}; Cytoplasmic side {ECO:0000269|PubMed:12042350}.
uniprot
proteins