Cmbl
entrez
310201
canonical
uniprot
Q7TP52
canonical
ensembl
ENSRNOG00000011260
resolver
ensembl
ENSRNOG00055025405
resolver
ensembl
ENSRNOG00060023422
resolver
ensembl
ENSRNOG00065012914
resolver
ensp
ENSRNOP00000015448
resolver
ensp
ENSRNOP00000079112
resolver
ensp
ENSRNOP00055035830
resolver
ensp
ENSRNOP00060033624
resolver
ensp
ENSRNOP00065016304
resolver
enst
ENSRNOT00055043845
resolver
enst
ENSRNOT00060040680
resolver
enst
ENSRNOT00065021138
resolver
genesymbol
Cmbl
resolver
uniprot_entry
CMBL_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Strongly inhibited by p-chloromercuribenzoate (PCMB). Partially inhibited by bis-p-nitrophenylphosphate (BNPP). Not inhibited by DFP, PMSF, eserine or EDTA. {ECO:0000250|UniProtKB:Q96DG6}.
uniprot
proteins
amino_acid_sequence
MANEANPCPCDIGHRLDYGGMGQEVQVEHIKAYVTRSPVDAGKAVIVVQDIFGWQLSNTRYMADMIAGNGYTTIVPDFFVGQEPWDPAGDWSTFPEWLKSRNARKINREVDAVLRYLKQQCHAQKIGIVGFCWGGIVVHHVMTTYPEVRAGVSVYGIIRDSEDVYNLKNPTLFIFAENDAVIPLEQVSILIQKLKEHCIVNYQVKTFSGQTHGFVHRKREDCSPADKPYIEEARRNLIEWLNKYI
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Cysteine hydrolase whose endogenous substrates and physiological function are unknown. In vitro, catalyzes the hydrolytic activation of several ester-based prodrugs, by cleaving the dioxolone ring to yield their respective active metabolites, diacetyl and CO2. {ECO:0000250|UniProtKB:Q96DG6}.
uniprot
proteins
mass_dalton
27903
uniprot
proteins
protein_family
Dienelactone hydrolase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
245
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q96DG6}.
uniprot
proteins