Ctdsp2
entrez
52468
canonical
uniprot
Q8BX07
canonical
ensembl
ENSMUSG00000078429
resolver
ensp
ENSMUSP00000100890
resolver
ensp
ENSMUSP00000100891
resolver
ensp
ENSMUSP00000249457
resolver
enst
ENSMUST00000105255
resolver
enst
ENSMUST00000105256
resolver
genesymbol
Ctdsp2
resolver
uniprot
F6U6J5
resolver
uniprot
Q8R3B3
resolver
uniprot_entry
CTDS2_MOUSE
resolver
uniprot_entry
F6U6J5_MOUSE
resolver
uniprot_entry
Q8R3B3_MOUSE
resolver
amino_acid_sequence
MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRSIFKALLCCFHTQHVVQSSSSTELTHKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEQDQGRICVVIDLDETLVHSSFKPINNADFIVPVEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFREACVFHQGCYVKDLSRLGRDLRKTVILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPVFEELSGTDDVYTSLGQLRAP
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
30546
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15681389
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
270
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins