Psrc1
entrez
691380
canonical
uniprot
Q3KR66
canonical
ensembl
ENSRNOG00000020013
resolver
ensp
ENSRNOP00000052733
resolver
ensp
ENSRNOP00000111385
resolver
enst
ENSRNOT00000055880
resolver
enst
ENSRNOT00000161076
resolver
genesymbol
Psrc1
resolver
genesymbol_syn
Dda3
resolver
uniprot
A0ABK0LZV9
resolver
uniprot_entry
A0ABK0LZV9_RAT
resolver
uniprot_entry
PSRC1_RAT
resolver
amino_acid_sequence
MEDLKEDIKFIVDETLDFGGLSPSDSHEEEDITVLVSPEKPLRRGLSHRSNPNAVAPALQGVRFSLGPLSPEKLEEILDEANRLAAQLEECALKDSENAAAGPGRPSPRGKPSPRRETFVLKDSPVRDLLPTVSSWSAPPPSNLTGLRSSDKKGSARAGRVTAGKKPSSIKKESPTCNLFSASKNPGRSPLAQPTLPPRRKTGSGARTVASPPIPVRPAPQSSASNSQCSSWLQGAAAKSSSRLPFPSAIPKPAIRMPLTGRSIPAGKGALAPDPLPTQKGHPSTVGHRAPVSQRTNLPTIGAARGRTSSAARGRVQPLRKAAVPGPTR
uniprot
proteins
function
FUNCTION: Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression (By similarity). {ECO:0000250|UniProtKB:Q6PGN9}.
uniprot
proteins
mass_dalton
34577
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis. {ECO:0000250}.
uniprot
proteins
protein_family
PSRC1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
329
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase (By similarity). {ECO:0000250}.
uniprot
proteins