Dpep3
entrez
364994
canonical
uniprot
Q5U2X4
canonical
ensembl
ENSRNOG00000019757
resolver
ensembl
ENSRNOG00055018181
resolver
ensembl
ENSRNOG00060012345
resolver
ensembl
ENSRNOG00065012254
resolver
ensp
ENSRNOP00000026809
resolver
ensp
ENSRNOP00055024795
resolver
ensp
ENSRNOP00060016492
resolver
ensp
ENSRNOP00065015270
resolver
enst
ENSRNOT00055030808
resolver
enst
ENSRNOT00060020917
resolver
enst
ENSRNOT00065019921
resolver
genesymbol
Dpep3
resolver
uniprot_entry
DPEP3_RAT
resolver
amino_acid_sequence
MQPTGPEGPRALSLRPLGHRLSLLGVLLIIPSLWVTCNQTTPSLSSAPTSPGASSAMTTPGIPNDTTTSGVTSDPRLREQALALMRDFPLVDGHNDLPLLLRELFQNKLQDVNLHNFTRGQTSLDRLRDGLVGAQFWSAYIPCQTQDRDAVRVALEQIDLIRRMCSAYPELELVTSADGLNSTQKLACLIGLEGGHSLDTSLAVLRSFYELGVRYLTLTFTCSTPWAESATKFRHHFYTNISGLTSFGEKVVEEMNRIGMMIDLSHASDTLVKQTLEASRAPVIFSHSAARSVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCSLLANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLLEELLRRGWGEQELQGVLRGNLLRVFRQVEQVREKSLGQSPVEVVFPERQQSSTCHSHLLPQSQDAHLKVTKLPSSQVLQRASKAPPCPLLGLVAAVTSPAFTLWLCCSGHR
uniprot
proteins
function
FUNCTION: Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem (By similarity). The absence of activity may be due to the inability of serine (instead of aspartate found in DPEP1/2) at position 356 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide (By similarity). {ECO:0000250|UniProtKB:Q9H4B8}.
uniprot
proteins
mass_dalton
53370
uniprot
proteins
protein_family
Metallo-dependent hydrolases superfamily
uniprot
proteins
protein_family
Peptidase M19 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
488
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q9DA79}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9DA79}.
uniprot
proteins