Hebp2
entrez
56016
canonical
uniprot
Q9WU63
canonical
ensembl
ENSMUSG00000019853
resolver
ensp
ENSMUSP00000020000
resolver
enst
ENSMUST00000020000
resolver
genesymbol
Hebp2
resolver
genesymbol_syn
Soul
resolver
uniprot_entry
HEBP2_MOUSE
resolver
amino_acid_sequence
MAEEPEPDLGVAEGSEDQALEMPSWKAPEDIDPQPGSYEIRHYGPAKWVSTCVESLDWDSAIQTGFTKLNGYIQGKNEKEMKIKLTAPVTSYVEPGSSPFSESTITISLYIPSEQQPDPPRPSESDVFIEDRAEMTVFVRSFDGFSSGQKNQEQLLTLANILREEGKVFNEKVFYTAGYSSPFQLLDRNNEVWLIQKNEPSVENK
uniprot
proteins
function
FUNCTION: Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions (By similarity). May have low affinity for heme (PubMed:15518569). {ECO:0000250|UniProtKB:Q9Y5Z4}.
uniprot
proteins
mass_dalton
23063
uniprot
proteins
mutagenesis
MUTAGEN 42; /note="H->A: Loss of heme binding."; /evidence="ECO:0000269|PubMed:15518569
uniprot
proteins
protein_family
HEBP family
uniprot
proteins
pubmed
10640688
uniprot
proteins
pubmed
15518569
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
205
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Y5Z4}. Mitochondrion {ECO:0000250|UniProtKB:Q9Y5Z4}. Note=Mainly localized to the cytoplasm with a much lower abundance in the mitochondrion. {ECO:0000250|UniProtKB:Q9Y5Z4}.
uniprot
proteins