PPP4R3B
entrez
57223
canonical
uniprot
Q5MIZ7
canonical
ensembl
ENSG00000275052
resolver
ensp
ENSP00000478677
resolver
ensp
ENSP00000483228
resolver
ensp
ENSP00000484116
resolver
ensp
ENSP00000560110
resolver
ensp
ENSP00000560111
resolver
ensp
ENSP00000560112
resolver
ensp
ENSP00000560113
resolver
ensp
ENSP00000560114
resolver
ensp
ENSP00000560116
resolver
ensp
ENSP00000560117
resolver
ensp
ENSP00000560122
resolver
ensp
ENSP00000560126
resolver
ensp
ENSP00000560127
resolver
ensp
ENSP00000560133
resolver
ensp
ENSP00000721897
resolver
genesymbol
PPP4R3B
resolver
genesymbol_syn
KIAA1387
resolver
genesymbol_syn
PP4R3B
resolver
genesymbol_syn
SMEK2
resolver
hgnc
HGNC:29267
resolver
uniprot
Q6P9B0
resolver
uniprot
Q86XB8
resolver
uniprot
Q9BQJ0
resolver
uniprot
Q9BRK2
resolver
uniprot
Q9H913
resolver
uniprot
Q9P2G0
resolver
uniprot_entry
P4R3B_HUMAN
resolver
uniprot_sec
Q6P9B0
resolver
uniprot_sec
Q86XB8
resolver
uniprot_sec
Q9BQJ0
resolver
uniprot_sec
Q9BRK2
resolver
uniprot_sec
Q9H913
resolver
uniprot_sec
Q9P2G0
resolver
amino_acid_sequence
MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEERFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHREFLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS
uniprot
proteins
function
FUNCTION: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
uniprot
proteins
mass_dalton
97458
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the SCF(FBXO42) complex; leading to proteasomal degradation. {ECO:0000269|PubMed:41484364}.
uniprot
proteins
protein_family
SMEK family
uniprot
proteins
pubmed
10718198
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616564
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16085932
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
18487071
uniprot
proteins
pubmed
18614045
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
41484364
uniprot
proteins
sequence_length
849
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18487071}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18487071}. Nucleus {ECO:0000269|PubMed:18487071}. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions.
uniprot
proteins