Ccdc93
entrez
70829
canonical
uniprot
Q7TQK5
canonical
ensembl
ENSMUSG00000026339
resolver
ensp
ENSMUSP00000043442
resolver
ensp
ENSMUSP00000108240
resolver
enst
ENSMUST00000036025
resolver
enst
ENSMUST00000112621
resolver
genesymbol
Ccdc93
resolver
uniprot
E9QAD4
resolver
uniprot
Q3TX53
resolver
uniprot
Q8BUE0
resolver
uniprot_entry
CCD93_MOUSE
resolver
uniprot_entry
E9QAD4_MOUSE
resolver
uniprot_entry
Q8BUE0_MOUSE
resolver
uniprot_sec
Q3TX53
resolver
amino_acid_sequence
MGLPKGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCSFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSISQFQKTYSLPEDDDFIKRKDKAVKTVVGLSDAYKPRRKYRRQRGAEELPDEESRVHSTLLEYGRRYGFSRQSKTEKAEDKKTALAAGLSAAEKVDAHEEDELQAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSEEIKQIVSEYAGKQSELSAEESPEKLGTSQLHQRKVISLNKQILQKSKHLEELQANHTSLKAKYSDRKKTLTELKDHGEKLDKEQAALEKLEAKADPSMLQNLRALVAMNESLKSQEQEFKAHCREEMARLQQEIETLKAERAPGEKIISGGEPQGALTSTMTHNEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNELLLSKIKAKAS
uniprot
proteins
function
FUNCTION: Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of composed of the CCC subcomplex and the retriever subcomplex (By similarity). Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels (By similarity). The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (By similarity). Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (By similarity). {ECO:0000250|UniProtKB:Q567U6}.
uniprot
proteins
mass_dalton
72603
uniprot
proteins
protein_family
CCDC93 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
629
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Early endosome {ECO:0000250|UniProtKB:Q567U6}.
uniprot
proteins