ADGRE5
entrez
976
canonical
uniprot
P48960
canonical
ensembl
ENSG00000123146
resolver
ensp
ENSP00000242786
resolver
ensp
ENSP00000349918
resolver
ensp
ENSP00000351413
resolver
genesymbol
ADGRE5
resolver
genesymbol_syn
CD97
resolver
hgnc
HGNC:1711
resolver
uniprot
A8K7Z4
resolver
uniprot
B2RBJ9
resolver
uniprot
O00718
resolver
uniprot
O76101
resolver
uniprot
Q8NG72
resolver
uniprot
Q8TBQ7
resolver
uniprot_entry
AGRE5_HUMAN
resolver
uniprot_sec
A8K7Z4
resolver
uniprot_sec
B2RBJ9
resolver
uniprot_sec
O00718
resolver
uniprot_sec
O76101
resolver
uniprot_sec
Q8NG72
resolver
uniprot_sec
Q8TBQ7
resolver
amino_acid_sequence
MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
uniprot
proteins
function
FUNCTION: Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. {ECO:0000250|UniProtKB:Q9Z0M6}.
uniprot
proteins
mass_dalton
91869
uniprot
proteins
post_translational_modification
PTM: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. {ECO:0000250}.
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
protein_family
LN-TM7 subfamily
uniprot
proteins
pubmed
11297558
uniprot
proteins
pubmed
12829604
uniprot
proteins
pubmed
14647991
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
7636245
uniprot
proteins
pubmed
8786105
uniprot
proteins
pubmed
8955192
uniprot
proteins
sequence_length
835
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9Z0M6}; Multi-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Adhesion G protein-coupled receptor E5 subunit alpha]: Secreted, extracellular space {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 553..572; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 582..601; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 621..642; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 654..674; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 692..712; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 740..760; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 767..789; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins