ADAM12
entrez
8038
canonical
uniprot
O43184
canonical
ensembl
ENSG00000148848
resolver
ensp
ENSP00000357665
resolver
ensp
ENSP00000357668
resolver
ensp
ENSP00000391268
resolver
enst
ENST00000448723
resolver
genesymbol
ADAM12
resolver
genesymbol_syn
MLTN
resolver
hgnc
HGNC:190
resolver
uniprot
A0ACM8QT74
resolver
uniprot
A8K6G4
resolver
uniprot
O60470
resolver
uniprot
Q5JRP0
resolver
uniprot
Q5JRP1
resolver
uniprot
Q5JRP2
resolver
uniprot
Q6P9E3
resolver
uniprot
Q6UWB0
resolver
uniprot
U5NE98
resolver
uniprot_entry
A0ACM8QT74_HUMAN
resolver
uniprot_entry
A8K6G4_HUMAN
resolver
uniprot_entry
ADA12_HUMAN
resolver
uniprot_entry
Q5JRP2_HUMAN
resolver
uniprot_sec
O60470
resolver
uniprot_sec
Q5JRP0
resolver
uniprot_sec
Q5JRP1
resolver
uniprot_sec
Q6P9E3
resolver
uniprot_sec
Q6UWB0
resolver
uniprot_sec
U5NE98
resolver
amino_acid_sequence
MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFDSKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTVILGHCYYHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCLLAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKPALRQAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVPRSTHTAYIK
uniprot
proteins
ec_number
3.4.24.-
uniprot
proteins
function
FUNCTION: Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
99542
uniprot
proteins
post_translational_modification
PTM: The precursor is cleaved by a furin endopeptidase. {ECO:0000250}.
uniprot
proteins
pubmed
10831617
uniprot
proteins
pubmed
12615925
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15574124
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
18621736
uniprot
proteins
pubmed
21618342
uniprot
proteins
pubmed
9417060
uniprot
proteins
pubmed
9642263
uniprot
proteins
sequence_length
909
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 4]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 709..729; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins