Orc4
entrez
26428
canonical
uniprot
O88708
canonical
ensembl
ENSMUSG00000026761
resolver
ensp
ENSMUSP00000028098
resolver
ensp
ENSMUSP00000088497
resolver
ensp
ENSMUSP00000119274
resolver
ensp
ENSMUSP00000285897
resolver
ensp
ENSMUSP00000285898
resolver
ensp
ENSMUSP00000285931
resolver
ensp
ENSMUSP00000328946
resolver
enst
ENSMUST00000028098
resolver
enst
ENSMUST00000090976
resolver
genesymbol
Orc4
resolver
genesymbol_syn
Orc4l
resolver
uniprot
F7CSJ7
resolver
uniprot
Q8C693
resolver
uniprot
Q91V62
resolver
uniprot
Q9CZF7
resolver
uniprot
Q9QYX1
resolver
uniprot_entry
F7CSJ7_MOUSE
resolver
uniprot_entry
ORC4_MOUSE
resolver
uniprot_entry
Q8C693_MOUSE
resolver
uniprot_entry
Q9CZF7_MOUSE
resolver
uniprot_sec
Q91V62
resolver
uniprot_sec
Q9QYX1
resolver
amino_acid_sequence
MSSRKTKSNAHAECLSQVQRILRERFCHHSPHSNLFGVQVQYKHLIELLKRTAIYGESNSVLIVGPRGSGKTTLLNHALKELMEIEVSENVIQVHLNGLLQTNEKIALKEITRQLNLDNVVEDKVFGSFAENLSFLLEALQKGDRTSSCPVIFILDEFDIFAHQKNQTLLYNLFDISQSAQTPVAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKAFAERWNENVHCLSEDSTVLEVLQKHFSVNKNLQSLHMLLMLALNRVTVSHPFMTSADLMEAQHMCSLDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQQLELIKPVERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL
uniprot
proteins
function
FUNCTION: Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity). Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. {ECO:0000250}.
uniprot
proteins
mass_dalton
49982
uniprot
proteins
protein_family
ORC4 family
uniprot
proteins
pubmed
10460412
uniprot
proteins
pubmed
12614612
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
433
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins