Mpp2
entrez
85275
canonical
uniprot
D3ZAA9
canonical
ensembl
ENSRNOG00000059683
resolver
ensembl
ENSRNOG00055033391
resolver
ensembl
ENSRNOG00060015166
resolver
ensembl
ENSRNOG00065026717
resolver
ensp
ENSRNOP00000072422
resolver
ensp
ENSRNOP00000073193
resolver
ensp
ENSRNOP00000101144
resolver
ensp
ENSRNOP00055047632
resolver
ensp
ENSRNOP00060020827
resolver
ensp
ENSRNOP00065037832
resolver
enst
ENSRNOT00000090456
resolver
enst
ENSRNOT00000161854
resolver
enst
ENSRNOT00055057746
resolver
enst
ENSRNOT00060026017
resolver
enst
ENSRNOT00065046111
resolver
genesymbol
Mpp2
resolver
uniprot
A0A8L2R7D6
resolver
uniprot
G3V8T8
resolver
uniprot_entry
A0A8L2R7D6_RAT
resolver
uniprot_entry
MPP2_RAT
resolver
uniprot_sec
G3V8T8
resolver
amino_acid_sequence
MPVAATNSESAMQQVLDNLGSLPNATGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEAVRDNNLELVQEILRDLAELAEQSSTAAELARILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRSASGSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGSAGLIPSQLLEEKRKAFVKRDLELTPTSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLILWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGVSTKQLTEADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY
uniprot
proteins
function
FUNCTION: Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (PubMed:27756895). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells (By similarity). {ECO:0000250|UniProtKB:Q14168, ECO:0000250|UniProtKB:Q9WV34, ECO:0000269|PubMed:27756895}.
uniprot
proteins
mass_dalton
61565
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SRC. {ECO:0000250|UniProtKB:Q14168}.
uniprot
proteins
protein_family
MAGUK family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
27756895
uniprot
proteins
sequence_length
552
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, dendrite {ECO:0000250|UniProtKB:Q9WV34}. Postsynaptic density {ECO:0000269|PubMed:27756895}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q14168}. Membrane {ECO:0000250|UniProtKB:Q14168}. Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. {ECO:0000250|UniProtKB:Q9WV34}.
uniprot
proteins