SLC10A4
entrez
201780
canonical
uniprot
Q96EP9
canonical
ensembl
ENSG00000145248
resolver
ensp
ENSP00000273861
resolver
enst
ENST00000273861
resolver
genesymbol
SLC10A4
resolver
hgnc
HGNC:22980
resolver
uniprot
Q8WUZ2
resolver
uniprot_entry
NTCP4_HUMAN
resolver
uniprot_sec
Q8WUZ2
resolver
amino_acid_sequence
MDGNDNVTLLFAPLLRDNYTLAPNASSLGPGTDLALAPASSAGPGPGLSLGPGPSFGFSPGPTPTPEPTTSGLAGGAASHGPSPFPRPWAPHALPFWDTPLNHGLNVFVGAALCITMLGLGCTVDVNHFGAHVRRPVGALLAALCQFGLLPLLAFLLALAFKLDEVAAVAVLLCGCCPGGNLSNLMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWIYSWAWINTPIVQLLPLGTVTLTLCSTLIPIGLGVFIRYKYSRVADYIVKVSLWSLLVTLVVLFIMTGTMLGPELLASIPAAVYVIAIFMPLAGYASGYGLATLFHLPPNCKRTVCLETGSQNVQLCTAILKLAFPPQFIGSMYMFPLLYALFQSAEAGIFVLIYKMYGSEMLHKRDPLDEDEDTDISYKKLKEEEMADTSYGTVKAENIIMMETAQTSL
uniprot
proteins
function
FUNCTION: No significant bile acid transporter activity could be measured despite its similarity to bile acid:sodium symporters. {ECO:0000269|PubMed:23589386}.
uniprot
proteins
mass_dalton
46504
uniprot
proteins
post_translational_modification
PTM: Activated following N-terminal proteolytic cleavage by thrombin and/or proteases. {ECO:0000269|PubMed:23589386}.
uniprot
proteins
protein_family
Bile acid:sodium symporter (BASS) (TC 2.A.28) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18355966
uniprot
proteins
pubmed
23589386
uniprot
proteins
sequence_length
437
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23589386}; Multi-pass membrane protein {ECO:0000269|PubMed:23589386}.
uniprot
proteins
transmembrane_region
TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 198..218; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 234..254; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 268..288; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 292..312; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 361..381; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins