Slc5a4b
entrez
64454
canonical
uniprot
Q91ZP4
canonical
ensembl
ENSMUSG00000020226
resolver
ensp
ENSMUSP00000113582
resolver
enst
ENSMUST00000120757
resolver
genesymbol
Slc5a4b
resolver
uniprot
Q2VPB3
resolver
uniprot
Q9ET36
resolver
uniprot_entry
Q2VPB3_MOUSE
resolver
uniprot_entry
S5A4B_MOUSE
resolver
uniprot_sec
Q9ET36
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by phlorizin. {ECO:0000269|PubMed:20392930}.
uniprot
proteins
amino_acid_sequence
MASTLSPSITPQTEEPPVVPVRIQNAADISVIVIYFIVVLAVGLWSMVRSNRGTVGGFFLAGHDMAWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNALLMVLVLGWVFLPIYIKAGVLTMPEYLRKRFGGKRLQIYLSVLSLFIMVALQTSSIIFSGAIFIQLALGLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAIPSVVEGDNLTISPKCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYWCADQVIVQRCLCGKNMSHVKAACILCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECEKQCGTAVGCTNYAYPTLVLELMPDGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRKKASERELMIAGRIFGMVLIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRVNEQGAFWGLMVGLVVGLIRLIAEFVYGTGSCVAPSNCPKIICGVHYMYFAIILFFVSIIVILGVSFLTEPIPDVHLYRLCWSLWNNTEERIDLDAEELETQEEAGGALEEDSEQSRGCLKRACCLLCGLQNTGPKLTKEEEAALRQKFSDTSEKPLWRTVMNINAVLLLGVAVFVHAYFA
uniprot
proteins
function
FUNCTION: Low-affinity sodium/D-glucose symporter (Probable) (PubMed:22301059). Generates D-glucose-induced depolarization in a pH-independent manner (PubMed:22301059). {ECO:0000269|PubMed:22301059, ECO:0000305|PubMed:20392930}.
uniprot
proteins
mass_dalton
72246
uniprot
proteins
protein_family
Sodium:solute symporter (SSF) (TC 2.A.21) family
uniprot
proteins
pubmed
11042146
uniprot
proteins
pubmed
11749115
uniprot
proteins
pubmed
12969150
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20392930
uniprot
proteins
pubmed
22301059
uniprot
proteins
sequence_length
660
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9ET37}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 28..48; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 83..103; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 143..163; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 278..298; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 381..401; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 424..444; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 456..476; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 485..505; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 527..547; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 640..660; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins