Dbn1
entrez
56320
canonical
uniprot
Q9QXS6
canonical
ensembl
ENSMUSG00000034675
resolver
ensp
ENSMUSP00000021950
resolver
ensp
ENSMUSP00000105547
resolver
ensp
ENSMUSP00000105549
resolver
ensp
ENSMUSP00000236190
resolver
ensp
ENSMUSP00000236192
resolver
ensp
ENSMUSP00000236195
resolver
ensp
ENSMUSP00000236196
resolver
ensp
ENSMUSP00000236197
resolver
ensp
ENSMUSP00000236198
resolver
ensp
ENSMUSP00000236200
resolver
ensp
ENSMUSP00000236202
resolver
ensp
ENSMUSP00000236203
resolver
ensp
ENSMUSP00000236204
resolver
ensp
ENSMUSP00000236208
resolver
ensp
ENSMUSP00000236211
resolver
ensp
ENSMUSP00000236213
resolver
ensp
ENSMUSP00000236225
resolver
ensp
ENSMUSP00000236227
resolver
ensp
ENSMUSP00000236235
resolver
enst
ENSMUST00000109921
resolver
genesymbol
Dbn1
resolver
genesymbol_syn
Drba
resolver
uniprot
A0A0R4J1E3
resolver
uniprot
A2CG16
resolver
uniprot
Q3TRK3
resolver
uniprot
Q3V234
resolver
uniprot
Q922X1
resolver
uniprot
Q9QXS5
resolver
uniprot_entry
A0A0R4J1E3_MOUSE
resolver
uniprot_entry
DREB_MOUSE
resolver
uniprot_entry
Q3TRK3_MOUSE
resolver
uniprot_sec
A2CG16
resolver
uniprot_sec
Q3V234
resolver
uniprot_sec
Q922X1
resolver
uniprot_sec
Q9QXS5
resolver
amino_acid_sequence
MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQSLEAEEAKRRLKEQSIFGDQRDEEEESQMKKSESEVEEAAAIIAQRPDNPREFFRQQERVASASGGSCDAPAPAPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPTRSPSDSSTASTPIAEQIERALDEVTSSQPPPPPPPPPPTQEAQETTPSLDEELSKEAKVTAAPEVWAGCAAEPPQAQEPPLLQSSPLEDSMCTESPEQAALAAPAEPAASVTSVADVHAADTIETTTATTDTTIANNVTPAAASLIDLWPGNGEEASTLQAEPRVPTPPSGAEASLAEVPLLNEAAQEPLPPVGEGCANLLNFDELPEPPATFCDPEEEVGETLAASQVLTMPSALEEVDQVLEQELEPEPHLLTNGETTQKEGTQASEGYFSQSQEEEFAQSEEPCAKVPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD
uniprot
proteins
function
FUNCTION: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (By similarity). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (By similarity). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (PubMed:25865831). Involved in memory-related synaptic plasticity in the hippocampus (PubMed:25865831). {ECO:0000250|UniProtKB:Q16643, ECO:0000269|PubMed:25865831}.
uniprot
proteins
mass_dalton
77287
uniprot
proteins
pubmed
10633083
uniprot
proteins
pubmed
11991718
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24720729
uniprot
proteins
pubmed
25865831
uniprot
proteins
sequence_length
706
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q16643}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q16643}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q16643}. Cell junction {ECO:0000250|UniProtKB:Q16643}. Cell projection {ECO:0000269|PubMed:24720729}. Cell projection, growth cone {ECO:0000269|PubMed:24720729}. Note=In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (By similarity). Colocalized with RUFY3 and F-actin at the transitional domain of the axonal growth cone (PubMed:24720729). {ECO:0000250|UniProtKB:Q16643, ECO:0000269|PubMed:24720729}.
uniprot
proteins