Commd8
entrez
27784
canonical
uniprot
Q9CZG3
canonical
ensembl
ENSMUSG00000029213
resolver
ensp
ENSMUSP00000013693
resolver
ensp
ENSMUSP00000142937
resolver
enst
ENSMUST00000013693
resolver
genesymbol
Commd8
resolver
uniprot
Q4QQP1
resolver
uniprot
Q9D7F6
resolver
uniprot_entry
COMD8_MOUSE
resolver
uniprot_entry
Q4QQP1_MOUSE
resolver
uniprot_sec
Q9D7F6
resolver
amino_acid_sequence
MEPEEGTPLWRLQKLPPEQGAGLLHKIIDGFCGRAYPAHQDYHSVWNSAEWKHVLEDVTTFFKAVVGKNFSEEETLQQLNQLNSCHQEAVLKCLKSRRNEIKQALLGEIVDISCAQLQDFDWQLKLALSSDKIATLQMPLLNLHLDVKEDDKVKPYTVEMSKEELQSLISSLEAANKVVLQLK
uniprot
proteins
function
FUNCTION: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity). May down-regulate activation of NF-kappa-B (By similarity). {ECO:0000250|UniProtKB:Q9NX08}.
uniprot
proteins
mass_dalton
20852
uniprot
proteins
protein_family
COMM domain-containing protein 8 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
183
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9NX08}. Nucleus {ECO:0000250|UniProtKB:Q9NX08}.
uniprot
proteins