H2AZ2
entrez
94239
canonical
uniprot
Q71UI9
canonical
ensembl
ENSG00000105968
resolver
ensp
ENSP00000222690
resolver
ensp
ENSP00000308405
resolver
ensp
ENSP00000340708
resolver
ensp
ENSP00000342714
resolver
ensp
ENSP00000370516
resolver
genesymbol
H2AZ2
resolver
genesymbol_syn
H2AFV
resolver
genesymbol_syn
H2AV
resolver
hgnc
HGNC:20664
resolver
uniprot
A6NFA8
resolver
uniprot
A6NKY0
resolver
uniprot
A6NN01
resolver
uniprot
A8MQC5
resolver
uniprot
Q59GV8
resolver
uniprot
Q6PK98
resolver
uniprot_entry
H2AV_HUMAN
resolver
uniprot_sec
A6NFA8
resolver
uniprot_sec
A6NKY0
resolver
uniprot_sec
A6NN01
resolver
uniprot_sec
A8MQC5
resolver
uniprot_sec
Q59GV8
resolver
uniprot_sec
Q6PK98
resolver
amino_acid_sequence
MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA
uniprot
proteins
function
FUNCTION: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
13509
uniprot
proteins
post_translational_modification
PTM: Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression. {ECO:0000250}.; PTM: Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Histone H2A family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16457589
uniprot
proteins
sequence_length
128
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
uniprot
proteins