Chdh
entrez
218865
canonical
uniprot
Q8BJ64
canonical
ensembl
ENSMUSG00000015970
resolver
ensp
ENSMUSP00000065542
resolver
ensp
ENSMUSP00000112916
resolver
enst
ENSMUST00000067620
resolver
enst
ENSMUST00000118917
resolver
genesymbol
Chdh
resolver
uniprot
Q3TPY4
resolver
uniprot
Q8CHT7
resolver
uniprot_entry
CHDH_MOUSE
resolver
uniprot_sec
Q3TPY4
resolver
uniprot_sec
Q8CHT7
resolver
amino_acid_sequence
MWQVLRGWRKGWQSPRGALAWAVQGQPCPPCSRAVASVGKDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLPYFRKAQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFEGTRAVGVEYIKDGQRHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQPGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKNVPVYKPQTLDTQR
uniprot
proteins
ec_number
1.1.99.1
uniprot
proteins
function
FUNCTION: Catalyzes the dehydrogenation of choline to betaine aldehyde in the mitochondria (PubMed:20371614). Involved in mitochondrial autophagy after mitochondrial damage (By similarity). {ECO:0000250|UniProtKB:Q8NE62, ECO:0000269|PubMed:20371614}.
uniprot
proteins
mass_dalton
66415
uniprot
proteins
pathway_participation
PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1.
uniprot
proteins
post_translational_modification
PTM: Acetylation of Lys-498 is observed in liver mitochondria from fasted mice but not from fed mice. {ECO:0000269|PubMed:23806337}.
uniprot
proteins
protein_family
GMC oxidoreductase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20371614
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
596
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:20371614}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8NE62}. Note=Accumulates on the mitochondrion outer membrane during following mitochondrial damage. {ECO:0000250|UniProtKB:Q8NE62}.
uniprot
proteins