Adipor1
entrez
72674
canonical
uniprot
Q91VH1
canonical
ensembl
ENSMUSG00000026457
resolver
ensp
ENSMUSP00000027727
resolver
ensp
ENSMUSP00000107856
resolver
enst
ENSMUST00000027727
resolver
enst
ENSMUST00000112237
resolver
genesymbol
Adipor1
resolver
genesymbol_syn
Paqr1
resolver
genesymbol_syn
Parq1
resolver
uniprot
Q3UPA4
resolver
uniprot
Q53YY4
resolver
uniprot
Q9CZA0
resolver
uniprot_entry
PAQR1_MOUSE
resolver
uniprot_entry
Q3UPA4_MOUSE
resolver
uniprot_entry
Q53YY4_MOUSE
resolver
uniprot_sec
Q9CZA0
resolver
amino_acid_sequence
MSSHKGSAGAQGNGAPSGNREADTVELAELGPLLEEKGKRAASSPAKAEEDQACPVPQEEEEEVRVLTLPLQAHHAMEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCTDDSLL
uniprot
proteins
function
FUNCTION: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:17268472, PubMed:17327425, PubMed:24742672). Required for normal glucose and fat homeostasis and for maintaining a normal body weight (PubMed:17327425, PubMed:24742672). ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis (PubMed:12802337, PubMed:17268472, PubMed:17327425, PubMed:24742672). Has high affinity for globular adiponectin and low affinity for full-length adiponectin (PubMed:12802337). {ECO:0000269|PubMed:12802337, ECO:0000269|PubMed:17268472, ECO:0000269|PubMed:17327425, ECO:0000269|PubMed:24742672}.
uniprot
proteins
mass_dalton
42366
uniprot
proteins
protein_family
ADIPOR family
uniprot
proteins
pubmed
12802337
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17268472
uniprot
proteins
pubmed
17327425
uniprot
proteins
pubmed
19661063
uniprot
proteins
pubmed
24742672
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17268472}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96A54}. Note=Localized to the cell membrane and intracellular organelles. {ECO:0000250|UniProtKB:Q96A54}.
uniprot
proteins
transmembrane_region
TRANSMEM 137..157; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q96A54"; TRANSMEM 171..191; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q96A54"; TRANSMEM 204..224; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q96A54"; TRANSMEM 235..255; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q96A54"; TRANSMEM 265..285; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q96A54"; TRANSMEM 299..319; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q96A54"; TRANSMEM 338..358; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q96A54
uniprot
proteins