EFNA4
entrez
1945
canonical
uniprot
P52798
canonical
ensembl
ENSG00000243364
resolver
ensp
ENSP00000352789
resolver
ensp
ENSP00000357394
resolver
ensp
ENSP00000414378
resolver
genesymbol
EFNA4
resolver
genesymbol_syn
EPLG4
resolver
genesymbol_syn
LERK4
resolver
hgnc
HGNC:3224
resolver
uniprot
C9JHJ8
resolver
uniprot
G3XAK2
resolver
uniprot
O95457
resolver
uniprot
Q5SR71
resolver
uniprot
Q6FI57
resolver
uniprot_entry
EFNA4_HUMAN
resolver
uniprot_sec
C9JHJ8
resolver
uniprot_sec
G3XAK2
resolver
uniprot_sec
O95457
resolver
uniprot_sec
Q5SR71
resolver
uniprot_sec
Q6FI57
resolver
amino_acid_sequence
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERKSESAHPVGSPGESGTSGWRGGDTPSPLCLLLLLLLLILRLLRIL
uniprot
proteins
function
FUNCTION: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
uniprot
proteins
mass_dalton
22386
uniprot
proteins
protein_family
Ephrin family
uniprot
proteins
pubmed
10607706
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
7838529
uniprot
proteins
sequence_length
201
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins