Tarm1
entrez
245126
canonical
uniprot
B6A8R8
canonical
ensembl
ENSMUSG00000053338
resolver
ensp
ENSMUSP00000145188
resolver
ensp
ENSMUSP00000145491
resolver
enst
ENSMUST00000203020
resolver
enst
ENSMUST00000203821
resolver
genesymbol
Tarm1
resolver
genesymbol_syn
Gm9904
resolver
uniprot
A0A0N4SVP3
resolver
uniprot_entry
A0A0N4SVP3_MOUSE
resolver
uniprot_entry
TARM1_MOUSE
resolver
amino_acid_sequence
MISRLLSLLCLRLCVGQTDIPENGSPPKPSLSAWPSTVLPTKSHVTMQCKSPTPSKYFILKKEGFALNSVKPYNLTEETADFHFTDLRQNDGGHYTCEYYSKWPHDTPSHPSNALFLLVTGYLPQPSFQAHHRGTVTAGSKVTLQCQKAGSVLGPVKFALLKVGHSTPVQTRSSTGMVSDFSLQNVTARDSGEYSCVYYQAKAPYRASGPSNLLEISVIDNHLPQDLAASTFPPQLTATSPKTPGTMTEGYTVDNLIRVGVAAAILLIVGGFLVEAWHSERLSPNKPW
uniprot
proteins
function
FUNCTION: May act as receptor. Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface. Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils. {ECO:0000269|PubMed:26311901}.
uniprot
proteins
mass_dalton
31392
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:B6A8C7}.
uniprot
proteins
pubmed
26311901
uniprot
proteins
sequence_length
288
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26311901}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 259..279; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins