FGFBP3
entrez
143282
canonical
uniprot
Q8TAT2
canonical
ensembl
ENSG00000174721
resolver
ensp
ENSP00000339067
resolver
enst
ENST00000311575
resolver
genesymbol
FGFBP3
resolver
genesymbol_syn
C10orf13
resolver
hgnc
HGNC:23428
resolver
uniprot
B2RD68
resolver
uniprot
Q8NBN0
resolver
uniprot_entry
FGFP3_HUMAN
resolver
uniprot_sec
B2RD68
resolver
uniprot_sec
Q8NBN0
resolver
amino_acid_sequence
MTPPKLRASLSPSLLLLLSGCLLAAARREKGAASNVAEPVPGPTGGSSGRFLSPEQHACSWQLLLPAPEAAAGSELALRCQSPDGARHQCAYRGHPERCAAYAARRAHFWKQVLGGLRKKRRPCHDPAPLQARLCAGKKGHGAELRLVPRASPPARPTVAGFAGESKPRARNRGRTRERASGPAAGTPPPQSAPPKENPSERKTNEGKRKAALVPNEERPMGTGPDPDGLDGNAELTETYCAEKWHSLCNFFVNFWNG
uniprot
proteins
function
FUNCTION: Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability. {ECO:0000269|PubMed:18669637}.
uniprot
proteins
mass_dalton
27590
uniprot
proteins
protein_family
Fibroblast growth factor-binding protein family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
18669637
uniprot
proteins
sequence_length
258
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18669637}.
uniprot
proteins