Cpsf2
entrez
51786
canonical
uniprot
O35218
canonical
ensembl
ENSMUSG00000041781
resolver
ensp
ENSMUSP00000047797
resolver
ensp
ENSMUSP00000302172
resolver
enst
ENSMUST00000047357
resolver
genesymbol
Cpsf2
resolver
genesymbol_syn
Cpsf100
resolver
genesymbol_syn
Mcpsf
resolver
uniprot
Q3UGU6
resolver
uniprot_entry
CPSF2_MOUSE
resolver
uniprot_entry
Q3UGU6_MOUSE
resolver
amino_acid_sequence
MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSVDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPTEKVTEIELRKRVKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDVDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVDAPSDSSAMAQQKAMKSLFGEDEKELGEETEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV
uniprot
proteins
function
FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
88383
uniprot
proteins
protein_family
CPSF2/YSH1 subfamily
uniprot
proteins
protein_family
Metallo-beta-lactamase superfamily
uniprot
proteins
protein_family
RNA-metabolizing metallo-beta-lactamase-like family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16115198
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17622165
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
782
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins