Pex13
entrez
305581
canonical
uniprot
D4A2Y9
canonical
ensembl
ENSRNOG00000054896
resolver
ensembl
ENSRNOG00055004104
resolver
ensembl
ENSRNOG00060007388
resolver
ensembl
ENSRNOG00065006008
resolver
ensp
ENSRNOP00000097867
resolver
ensp
ENSRNOP00055005007
resolver
ensp
ENSRNOP00060009163
resolver
ensp
ENSRNOP00065006467
resolver
enst
ENSRNOT00000104301
resolver
enst
ENSRNOT00055006556
resolver
enst
ENSRNOT00060012147
resolver
enst
ENSRNOT00065009077
resolver
genesymbol
Pex13
resolver
uniprot
A0A8I6AVL0
resolver
uniprot_entry
PEX13_RAT
resolver
uniprot_sec
A0A8I6AVL0
resolver
amino_acid_sequence
MASQPPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLLTRPGQPTLTRVPPPILPRPSQQTGGNNVNTFRPAYSSFSSGYGAYGNAFYGSYSPYSYGYNGLGFNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQWMMGLRRGSENEDLWAESEGTVACLGAEDQANNSAKSWPIFLFFAVILGGPYLIWKLLSTHSDEVTDSTNWANGEDDHVVARAEYDFAAVSDEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRRGRKTVESSTMPKQQQSFTNPTSVKGVTTTNSLEEQEAAFESVFVETNKVAGTPDSTGKNGDKQDL
uniprot
proteins
function
FUNCTION: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix. Involved in the import of PTS1- and PTS2-type containing proteins (By similarity). {ECO:0000250|UniProtKB:P80667, ECO:0000250|UniProtKB:Q92968}.
uniprot
proteins
mass_dalton
44264
uniprot
proteins
protein_family
Peroxin-13 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
30414318
uniprot
proteins
sequence_length
403
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000269|PubMed:30414318}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 135..155; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 175..192; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 234..254; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins