Nat8l
entrez
289727
canonical
uniprot
D3ZVU9
canonical
ensembl
ENSRNOG00000049351
resolver
ensembl
ENSRNOG00055017058
resolver
ensembl
ENSRNOG00060016939
resolver
ensembl
ENSRNOG00065029566
resolver
ensp
ENSRNOP00000066413
resolver
ensp
ENSRNOP00055023311
resolver
ensp
ENSRNOP00060023318
resolver
ensp
ENSRNOP00065041989
resolver
enst
ENSRNOT00000074734
resolver
enst
ENSRNOT00055028959
resolver
enst
ENSRNOT00060028962
resolver
enst
ENSRNOT00065051044
resolver
genesymbol
Nat8l
resolver
uniprot_entry
NAT8L_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Aminooxyacetic acid (AOAA) blocks its activity in both cytoplasm and mitochondria. {ECO:0000250|UniProtKB:Q8N9F0}.
uniprot
proteins
amino_acid_sequence
MHCGPPDMVCETKIVATEDHEALPGAKKDALLAAAGAMWPPLPAAPGPAAAPPPAAGPQPHGGTGGAGPPEGRGVCIREFRAAEQEAARRIFYDGILERIPNTAFRGLRQHPRTQLLYALLAALCFAVTRSLLLTCLVPAGLLALRYYYSRKVILAYLECALHTDMADIEQYYMKPPGSCFWVAVLDGNVVGIVAARAHEEDNTVELLRMSVDSRFRGKGIAKALGRRVLEFAMLHNYSAVVLGTTAVKVAAHKLYESLGFRHMGASDHYVLPGMTLSLAERLFFQVRYHRYRLQLREE
uniprot
proteins
ec_number
2.3.1.17
uniprot
proteins
function
FUNCTION: Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA (PubMed:18621030). Promotes dopamine uptake by regulating TNF expression (By similarity). Attenuates methamphetamine-induced inhibition of dopamine uptake (By similarity). {ECO:0000250|UniProtKB:Q3UGX3, ECO:0000250|UniProtKB:Q8N9F0, ECO:0000269|PubMed:18621030}.
uniprot
proteins
mass_dalton
32719
uniprot
proteins
protein_family
NAT8 family
uniprot
proteins
pubmed
18621030
uniprot
proteins
pubmed
20385109
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8N9F0}. Microsome membrane {ECO:0000269|PubMed:18621030}; Single-pass type I membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:18621030}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q3UGX3}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 118..138; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins