ITIH1
entrez
3697
canonical
uniprot
P19827
canonical
ensembl
ENSG00000055957
resolver
ensp
ENSP00000273283
resolver
ensp
ENSP00000443847
resolver
genesymbol
ITIH1
resolver
genesymbol_syn
IGHEP1
resolver
hgnc
HGNC:6166
resolver
uniprot
A8K9N5
resolver
uniprot
B2RAH9
resolver
uniprot
B7Z558
resolver
uniprot
B7Z8B6
resolver
uniprot
B7Z8C0
resolver
uniprot
F5H165
resolver
uniprot
F5H7Y8
resolver
uniprot
P78455
resolver
uniprot
Q01746
resolver
uniprot
Q562G1
resolver
uniprot_entry
B7Z8B6_HUMAN
resolver
uniprot_entry
ITIH1_HUMAN
resolver
uniprot_sec
A8K9N5
resolver
uniprot_sec
B2RAH9
resolver
uniprot_sec
B7Z558
resolver
uniprot_sec
B7Z8C0
resolver
uniprot_sec
F5H165
resolver
uniprot_sec
F5H7Y8
resolver
uniprot_sec
P78455
resolver
uniprot_sec
Q01746
resolver
uniprot_sec
Q562G1
resolver
amino_acid_sequence
MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF
uniprot
proteins
function
FUNCTION: May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.; FUNCTION: Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.
uniprot
proteins
mass_dalton
101389
uniprot
proteins
mutagenesis
MUTAGEN 298; /note="D->A: Abolishes binding to CUB domain of TNFAIP6."; /evidence="ECO:0000269|PubMed:26468290
uniprot
proteins
post_translational_modification
PTM: Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.; PTM: The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal. {ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:9425062, ECO:0000269|PubMed:9677337}.
uniprot
proteins
protein_family
ITIH family
uniprot
proteins
pubmed
12754519
uniprot
proteins
pubmed
1380832
uniprot
proteins
pubmed
1384548
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14760718
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2446322
uniprot
proteins
pubmed
2471637
uniprot
proteins
pubmed
2476436
uniprot
proteins
pubmed
26468290
uniprot
proteins
pubmed
3663330
uniprot
proteins
pubmed
7504674
uniprot
proteins
pubmed
7505744
uniprot
proteins
pubmed
7513643
uniprot
proteins
pubmed
7522574
uniprot
proteins
pubmed
7535743
uniprot
proteins
pubmed
9425062
uniprot
proteins
pubmed
9677337
uniprot
proteins
sequence_length
911
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins