DLGAP5
entrez
9787
canonical
uniprot
Q15398
canonical
ensembl
ENSG00000126787
resolver
ensp
ENSP00000247191
resolver
ensp
ENSP00000378815
resolver
ensp
ENSP00000610563
resolver
genesymbol
DLGAP5
resolver
genesymbol_syn
DLG7
resolver
genesymbol_syn
KIAA0008
resolver
hgnc
HGNC:16864
resolver
uniprot
A8MTM6
resolver
uniprot
B4DRM8
resolver
uniprot
Q86T11
resolver
uniprot
Q8NG58
resolver
uniprot_entry
DLGP5_HUMAN
resolver
uniprot_sec
A8MTM6
resolver
uniprot_sec
B4DRM8
resolver
uniprot_sec
Q86T11
resolver
uniprot_sec
Q8NG58
resolver
amino_acid_sequence
MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRILVELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKVGRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPRQTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEGKVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAKIKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEILAQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNEGRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKERFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNNMNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVIPKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQTTSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLSSERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILEEGETKISQSELFDNKSLTTECHLLDSPGLNCSNPFTQLERRHQEHARHISFGGNLITFSPLQPGEF
uniprot
proteins
function
FUNCTION: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. {ECO:0000269|PubMed:12527899, ECO:0000269|PubMed:14699157, ECO:0000269|PubMed:15145941}.
uniprot
proteins
mass_dalton
95115
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation. {ECO:0000269|PubMed:15145941}.; PTM: Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells. {ECO:0000269|PubMed:14699157, ECO:0000269|PubMed:15145941, ECO:0000269|PubMed:15987997}.
uniprot
proteins
protein_family
SAPAP family
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
12527899
uniprot
proteins
pubmed
14699157
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15145941
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15561729
uniprot
proteins
pubmed
15987997
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
7584026
uniprot
proteins
sequence_length
846
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
uniprot
proteins