Jph3
entrez
57340
canonical
uniprot
Q9ET77
canonical
ensembl
ENSMUSG00000025318
resolver
ensp
ENSMUSP00000026357
resolver
ensp
ENSMUSP00000126190
resolver
enst
ENSMUST00000026357
resolver
enst
ENSMUST00000167439
resolver
genesymbol
Jph3
resolver
genesymbol_syn
Jp3
resolver
uniprot
Q3ZAS3
resolver
uniprot
Q8BNM7
resolver
uniprot
Q9EQZ2
resolver
uniprot_entry
JPH3_MOUSE
resolver
uniprot_sec
Q3ZAS3
resolver
uniprot_sec
Q8BNM7
resolver
uniprot_sec
Q9EQZ2
resolver
amino_acid_sequence
MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGAALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKHQMSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPASPTSTPPPAPASRTKMAHFSRQVSVDEERSGDIQMLLEGRGGDYARNSWGEEKAGASRGIRSGALRSGQPTEDFRTRGSGHKQPGNPKPRERRTESPTTFSWTSHHRAGNPCSGGPKLLEPDEEQLSNYKLEMKPLLRMDACPQDTHPQRRRHSRGAGGDRGFGLQRLRSKSQNKENLRPASSAEPTVQKLESLRLGDRPEPRLLRWDLTFSPPQKSLPVALESDEETGDELKSSTGSAPILVVMVILLNIGVAILFINFFI
uniprot
proteins
function
FUNCTION: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory. {ECO:0000269|PubMed:11906164, ECO:0000269|PubMed:16809425}.
uniprot
proteins
mass_dalton
81229
uniprot
proteins
protein_family
Junctophilin family
uniprot
proteins
pubmed
10949023
uniprot
proteins
pubmed
11906164
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
16809425
uniprot
proteins
pubmed
17904530
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
744
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane.
uniprot
proteins
transmembrane_region
TRANSMEM 724..744; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins