FAF1
entrez
11124
canonical
uniprot
Q9UNN5
canonical
ensembl
ENSG00000185104
resolver
ensp
ENSP00000379457
resolver
genesymbol
FAF1
resolver
genesymbol_syn
UBXD12
resolver
genesymbol_syn
UBXN3A
resolver
hgnc
HGNC:3578
resolver
uniprot
Q549F0
resolver
uniprot
Q9UF34
resolver
uniprot
Q9UNT3
resolver
uniprot
Q9Y2Z3
resolver
uniprot_entry
FAF1_HUMAN
resolver
uniprot_sec
Q549F0
resolver
uniprot_sec
Q9UF34
resolver
uniprot_sec
Q9UNT3
resolver
uniprot_sec
Q9Y2Z3
resolver
amino_acid_sequence
MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPASHPASAPTSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTCTVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGWPTSATDDSMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDATEFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDSNRARFLTMCNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLEAKE
uniprot
proteins
function
FUNCTION: Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564). Potentiates but cannot initiate FAS-induced apoptosis (By similarity). {ECO:0000250|UniProtKB:P54731, ECO:0000269|PubMed:19722279, ECO:0000269|PubMed:26842564}.
uniprot
proteins
mass_dalton
73954
uniprot
proteins
pubmed
10462485
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
11243799
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
19722279
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21978668
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26842564
uniprot
proteins
sequence_length
650
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:26842564}.
uniprot
proteins