P70224
uniprot
P70224
canonical
amino_acid_sequence
MPQLRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRMWAGWQVEVVDTPDIFSSEIPRTDPGCVETARCFVLSAPGPHALLLVTQLGRFTMQDSQALAAVKRLFGKQVMARTVVVFTRQEDLAGDSLQDYVHCTDNRALRDLVAECGGRVCALNNRATGSEREAQAEQLLGMVACLVREHGGAHYSNEVYELVQDTRCADPQDQVAKVAEIVAERMQRRTRLLAGLWGWRKFYWKGWRRGFSVFLGVAILIYLLFYRKGFGDQNNR
uniprot
proteins
function
FUNCTION: May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells. {ECO:0000269|PubMed:20194894}.
uniprot
proteins
mass_dalton
30829
uniprot
proteins
protein_family
AIG1/Toc34/Toc159-like paraseptin GTPase family
uniprot
proteins
protein_family
IAN subfamily
uniprot
proteins
protein_family
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
uniprot
proteins
pubmed
10446218
uniprot
proteins
pubmed
11814688
uniprot
proteins
pubmed
16509771
uniprot
proteins
pubmed
20194894
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21487483
uniprot
proteins
pubmed
9020038
uniprot
proteins
sequence_length
277
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:11814688, ECO:0000269|PubMed:21487483}; Single-pass type IV membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:21487483}; Single-pass type IV membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 251..266; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins