Rxfp1
entrez
295144
canonical
uniprot
Q6R6I6
canonical
ensembl
ENSRNOG00000024120
resolver
ensp
ENSRNOP00000081726
resolver
genesymbol
Rxfp1
resolver
genesymbol_syn
Lgr7
resolver
uniprot_entry
RXFP1_RAT
resolver
amino_acid_sequence
MTSGPFFFCVFIIGRYFTLGNAQDVSCPLGSFPCGNISKCLPQLLHCNGVDDCGNQADEDNCGDNNGWSLQLDKYFANYYKLTSTNSIEAETSECLVGSVPMHCLCRDLELDCDEANLRAVPSVSSNVTVMSLQWNFIRTLPPNSFRKYHDLQKLCLQNNKIRSVSVSAFRGLHSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPLTFYGLNSLILLVLMNNALTRLPDKPLCQHMPRLHWLDFEGNRIHNLRNLTFISCNNLTVLVMRKNKINHLNEHAFTHLQKLDELDLGSNKIENLPPNIFKDLKELSQLNISYNPIQKIEVNQFDYLAKLKSLSLEGIEISNIQQRMFRPLINLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAITCFGNIFVICMRPYIRSENKLHAMSIMSLCCADCLMGVYLFVIGAFDLKFRGEYRKHAQPWMESVHCQFMGSLAVLSTEVSVLLLTFLTLEKYICIVYPFRCLRPRKCRTVAVLIFIWITGFIVAFAPLGNKEFFKNYYGTNGVCFPLHSEDTGSTGAQIYSVVIFLGINLVAFIIIVFSYGSMFYSVHQSTITATEIQKQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLIRVEIPDTITSWVVIFILPINSALNPIIYTLTTRPFKEMIHQLWYNYRQRRSVDRKGTQKAYTPSFIWVEMWPLQEMSTEFMKPDAFTDPCDLSLVSRSSRLNSYS
uniprot
proteins
function
FUNCTION: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP (By similarity). {ECO:0000250, ECO:0000269|PubMed:15566402}.
uniprot
proteins
mass_dalton
87183
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15566402
uniprot
proteins
sequence_length
758
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15566402}; Multi-pass membrane protein {ECO:0000269|PubMed:15566402}.
uniprot
proteins
transmembrane_region
TRANSMEM 409..429; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 444..464; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 487..507; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 528..548; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 578..598; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 630..650; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 661..681; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins