Sulf1
entrez
240725
canonical
uniprot
Q8K007
canonical
ensembl
ENSMUSG00000016918
resolver
ensp
ENSMUSP00000085949
resolver
ensp
ENSMUSP00000136014
resolver
ensp
ENSMUSP00000137523
resolver
ensp
ENSMUSP00000141153
resolver
ensp
ENSMUSP00000237352
resolver
enst
ENSMUST00000088585
resolver
enst
ENSMUST00000177608
resolver
enst
ENSMUST00000180062
resolver
genesymbol
Sulf1
resolver
genesymbol_syn
Kiaa1077
resolver
uniprot
Q6ZPZ0
resolver
uniprot
Q8BLJ0
resolver
uniprot
Q8C1D3
resolver
uniprot_entry
SULF1_MOUSE
resolver
uniprot_sec
Q6ZPZ0
resolver
uniprot_sec
Q8BLJ0
resolver
uniprot_sec
Q8C1D3
resolver
amino_acid_sequence
MKYSLWALLLAVLGTQLLGSLCSTVRSQRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEQGGATFTNAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPIMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNVLQRKRLQTLMSVDDSVERLYNMLVESGELDNTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSIEPGSIVPQIVLNIDLAPTILDIAGLDSPSDVDGKSVLKLLDLEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESGKNIQQSNHLPKYERVKELCQQARYQTACEQPGQNWQCIEDTSGKLRIHKCKGPSDLLTVRQNARNLYSRGLHDKDKECHCRDSGYRSSRSQRKNQRQFLRNKGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEELQVLPPRSIAKRHDEGHQGFIGHQAAAGDIRNEMLADSNNAVGLPATVRVTHKCFILPNDTIHCERELYQSARAWKDHKAYIDKEIEVLQDKIKNLREVRGHLKKRKPEECGCGDQSYYNKEKGVKRQEKLKSHLHPFKEAAAQEVDSKLQLFKEHRRRKKERKEKKRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERSILNQLHIQLMELRSCQGYKQCNPRPKSLDIGAKEGGNYDPHRGQLWDGWEG
uniprot
proteins
ec_number
3.1.6.1
uniprot
proteins
ec_number
3.1.6.14
uniprot
proteins
function
FUNCTION: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (By similarity). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin (By similarity). Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation (By similarity). {ECO:0000250|UniProtKB:Q8IWU6}.
uniprot
proteins
mass_dalton
100923
uniprot
proteins
post_translational_modification
PTM: Processing by furin produces a secreted form. {ECO:0000269|PubMed:12368295}.; PTM: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. {ECO:0000250|UniProtKB:P15289}.
uniprot
proteins
protein_family
Sulfatase family
uniprot
proteins
pubmed
12368295
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
870
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8VI60}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q8VI60}. Cell surface {ECO:0000269|PubMed:12368295}.; SUBCELLULAR LOCATION: [Extracellular sulfatase Sulf-2 secreted form]: Secreted {ECO:0000269|PubMed:12368295}.
uniprot
proteins