LEFTY1
entrez
10637
canonical
uniprot
O75610
canonical
ensembl
ENSG00000243709
resolver
ensp
ENSP00000272134
resolver
enst
ENST00000272134
resolver
genesymbol
LEFTY1
resolver
genesymbol_syn
LEFTB
resolver
genesymbol_syn
LEFTYB
resolver
hgnc
HGNC:6552
resolver
uniprot
B2R7U0
resolver
uniprot
Q53H67
resolver
uniprot
Q5TE94
resolver
uniprot_entry
LFTY1_HUMAN
resolver
uniprot_sec
B2R7U0
resolver
uniprot_sec
Q53H67
resolver
uniprot_sec
Q5TE94
resolver
amino_acid_sequence
MQPLWLCWALWVLPLASPGAALTGEQLLGSLLRQLQLKEVPTLDRADMEELVIPTHVRAQYVALLQRSHGDRSRGKRFSQSFREVAGRFLALEASTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSARARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRFASQGAPAGLGEPQLELHTLDLGDYGAQGDCDPEAPMTEGTRCCRQEMYIDLQGMKWAENWVLEPPGFLAYECVGTCRQPPEALAFKWPFLGPRQCIASETDSLPMIVSIKEGGRTRPQVVSLPNMRVQKCSCASDGALVPRRLQP
uniprot
proteins
function
FUNCTION: Required for left-right axis determination as a regulator of LEFTY2 and NODAL.
uniprot
proteins
mass_dalton
40880
uniprot
proteins
post_translational_modification
PTM: The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.
uniprot
proteins
protein_family
TGF-beta family
uniprot
proteins
pubmed
10053005
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
sequence_length
366
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins