Ddi1
entrez
367012
canonical
uniprot
A0JPP7
canonical
ensembl
ENSRNOG00000022081
resolver
ensembl
ENSRNOG00065002762
resolver
ensp
ENSRNOP00000091127
resolver
ensp
ENSRNOP00065002653
resolver
enst
ENSRNOT00000039868
resolver
enst
ENSRNOT00065003775
resolver
genesymbol
Ddi1
resolver
uniprot_entry
DDI1_RAT
resolver
amino_acid_sequence
MLITVYCVRRDLTEVTFSLQVNPDFELSNFRVLCELESGVPAEEAQIVYMEQLLTDDHCSLGSYGLKDGDMVVLLQKDNVGPRPPGRAPNHPRTDFTGSGSAVPGTSSSRHPHPHQHHHHQHQRIPSTQQAHGLASGENMAFAQDLNSPALIRSMLLSNPHDLSLLKERNPALAEALLSGNLETFSQVLVEQQRERAMREQEMFRLYSADPFDQETQARIEEEIRQQNIEENMNIAMEEAPESFGQVAMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGVAKGVGTQRIMGRVHLAQIQIEGDFLQCSFSILEEQPMDILLGLDMLRRHQCSIDLKKNVLVIGTTGSQTHFLPEGELPLCAKLLSGAVQEDSSDKEVAGSIKHPVKGPGRKKH
uniprot
proteins
ec_number
3.4.23.-
uniprot
proteins
function
FUNCTION: Probable aspartic protease (By similarity). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, for cellular survival following replication stress. Together or redundantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (By similarity). {ECO:0000250|UniProtKB:I7HUG0, ECO:0000250|UniProtKB:Q8WTU0}.
uniprot
proteins
mass_dalton
45451
uniprot
proteins
protein_family
DDI1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
408
uniprot
proteins