DPH6
entrez
89978
canonical
uniprot
Q7L8W6
canonical
ensembl
ENSG00000134146
resolver
ensp
ENSP00000256538
resolver
ensp
ENSP00000406976
resolver
ensp
ENSP00000679253
resolver
ensp
ENSP00000679255
resolver
ensp
ENSP00000732110
resolver
ensp
ENSP00000775424
resolver
ensp
ENSP00000775426
resolver
ensp
ENSP00000775429
resolver
genesymbol
DPH6
resolver
genesymbol_syn
ATPBD4
resolver
hgnc
HGNC:30543
resolver
uniprot
B3KWG1
resolver
uniprot
Q96HJ6
resolver
uniprot_entry
DPH6_HUMAN
resolver
uniprot_sec
B3KWG1
resolver
uniprot_sec
Q96HJ6
resolver
amino_acid_sequence
MRVAALISGGKDSCYNMMQCIAAGHQIVALANLRPAENQVGSDELDSYMYQTVGHHAIDLYAEAMALPLYRRTIRGRSLDTRQVYTKCEGDEVEDLYELLKLVKEKEEVEGISVGAILSDYQRIRVENVCKRLNLQPLAYLWQRNQEDLLREMISSNIQAMIIKVAALGLDPDKHLGKTLDQMEPYLIELSKKYGVHVCGEGGEYETFTLDCPLFKKKIIVDSSEVVIHSADAFAPVAYLRFLELHLEDKVSSVPDNYRTSNYIYNF
uniprot
proteins
ec_number
6.3.1.14
uniprot
proteins
function
FUNCTION: Amidase that may catalyze the last step of diphthamide biosynthesis using ammonium and ATP (PubMed:23169644). Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor (EEF2) to diphthamide (By similarity). {ECO:0000250|UniProtKB:Q12429, ECO:0000269|PubMed:23169644}.
uniprot
proteins
mass_dalton
30307
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; peptidyl-diphthamide biosynthesis.
uniprot
proteins
protein_family
Diphthine--ammonia ligase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23169644
uniprot
proteins
sequence_length
267
uniprot
proteins