Slc9d1
entrez
234076
canonical
uniprot
Q8BH01
canonical
ensembl
ENSMUSG00000038497
resolver
ensp
ENSMUSP00000040347
resolver
ensp
ENSMUSP00000309129
resolver
ensp
ENSMUSP00000333956
resolver
genesymbol
Slc9d1
resolver
genesymbol_syn
Tmco3
resolver
uniprot
Q3UFX1
resolver
uniprot
Q7TMT5
resolver
uniprot
Q8BGL4
resolver
uniprot
Q8R303
resolver
uniprot_entry
SL9D1_MOUSE
resolver
uniprot_sec
Q3UFX1
resolver
uniprot_sec
Q7TMT5
resolver
uniprot_sec
Q8BGL4
resolver
uniprot_sec
Q8R303
resolver
amino_acid_sequence
MKVLDQSLLWMLLPFFHLIASAAEHEEVAKHAIKLHRGKGATATQRKQWALDSCRRLTGLLRQKNVVLNKLKNAIRAVEKDTSLSGEEKLFQVHTFEIFQKELNESENSIFQAIYGLQRALQGDYRDVVNMKESSKQRLEALREAAIKEETEYVELLAAEKHQVEALKNMQHQNKSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEASSKQNMTKREVEDGLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYIICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWRISLQGPCYMTLLMIAFGLWWGHLLRIRPTQSVFISTCLSLSSTPLVSRFLVGSARGDKEAGDIDYSTVLLGMLVMQDVQLGLFIAVMPTLIQAGAGASSSVVMEVLRILFLIGQILFSLAAVFLLCLVMKTYLIGPYYRKLHLESKGNKEILVLGVSAFTFLMLTVTELLDVSMELGCFLAGALVSSQGHMVTEEIMTYIEPIRDFLAIIFFASIGLHVFPTFVIYELTVLVFLTLSVVIMKFVLAVLVLSLILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGILSREVYLLILSVTTLSLLLAPVLWKAAITKCVPRPERRSSL
uniprot
proteins
function
FUNCTION: Probable Na(+):H(+) or K(+):H(+) antiporter (Probable). Upon IGF1-dependent phosphorylation, facilitates the membrane translocation and activation of AKT1 (By similarity). {ECO:0000250|UniProtKB:Q6UWJ1, ECO:0000305|PubMed:37554015}.
uniprot
proteins
mass_dalton
75903
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Ser-85 induced by IGF1 facilitates the membrane translocation and activation of AKT1. {ECO:0000250|UniProtKB:Q6UWJ1}.
uniprot
proteins
protein_family
Monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
37554015
uniprot
proteins
sequence_length
678
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:37554015}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q6UWJ1}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 286..306; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 317..337; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 350..370; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 417..437; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 457..477; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 499..519; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 555..575; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 579..599; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 609..629; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 641..661; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins