PPWD1
entrez
23398
canonical
uniprot
Q96BP3
canonical
ensembl
ENSG00000113593
resolver
ensp
ENSP00000261308
resolver
ensp
ENSP00000442371
resolver
ensp
ENSP00000444496
resolver
enst
ENST00000535264
resolver
genesymbol
PPWD1
resolver
genesymbol_syn
KIAA0073
resolver
hgnc
HGNC:28954
resolver
uniprot
A0A384MTS1
resolver
uniprot
B4DP34
resolver
uniprot
B4DT22
resolver
uniprot
B4DWR9
resolver
uniprot
F5H7P7
resolver
uniprot
Q15002
resolver
uniprot
Q7KZ89
resolver
uniprot_entry
A0A384MTS1_HUMAN
resolver
uniprot_entry
B4DP34_HUMAN
resolver
uniprot_entry
B4DT22_HUMAN
resolver
uniprot_entry
F5H7P7_HUMAN
resolver
uniprot_entry
PPWD1_HUMAN
resolver
uniprot_sec
B4DWR9
resolver
uniprot_sec
Q15002
resolver
uniprot_sec
Q7KZ89
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by cyclosporin A (CsA). {ECO:0000305|PubMed:20676357}.
uniprot
proteins
amino_acid_sequence
MAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATLAKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK
uniprot
proteins
ec_number
5.2.1.8
uniprot
proteins
function
FUNCTION: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). May be involved in pre-mRNA splicing (PubMed:11991638). {ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:20676357}.
uniprot
proteins
mass_dalton
73575
uniprot
proteins
protein_family
Cyclophilin-type PPIase family
uniprot
proteins
protein_family
PPIL1 subfamily
uniprot
proteins
pubmed
11991638
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18397323
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20676357
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
7584044
uniprot
proteins
sequence_length
646
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18397323}. Note=Associated with spliceosomal complexes. {ECO:0000269|PubMed:11991638}.
uniprot
proteins