Ivd
entrez
24513
canonical
uniprot
P12007
canonical
ensembl
ENSRNOG00000009421
resolver
ensembl
ENSRNOG00055002697
resolver
ensembl
ENSRNOG00060025127
resolver
ensembl
ENSRNOG00065023036
resolver
ensp
ENSRNOP00000013829
resolver
ensp
ENSRNOP00055003194
resolver
ensp
ENSRNOP00060036064
resolver
ensp
ENSRNOP00065032042
resolver
enst
ENSRNOT00055004286
resolver
enst
ENSRNOT00060043516
resolver
enst
ENSRNOT00065039414
resolver
genesymbol
Ivd
resolver
uniprot_entry
IVD_RAT
resolver
amino_acid_sequence
MATAVRLLGRRVSSWRLRPLPSPLAVPQRAHSMLPVDDDINGLNEEQKQLRHTISKFVQENLAPKAQEIDQSNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASAAVGLSYGAHSNLCINQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMRLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDLTAVPASRGITAFIVEKDMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANILSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMACRQYVYNVARACDEGHITAKDCAGVILYTAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGGGTSEVRRLVIGRAFNADFR
uniprot
proteins
ec_number
1.3.8.1
uniprot
proteins
ec_number
1.3.8.4
uniprot
proteins
function
FUNCTION: A mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism, where isovaleryl-CoA (3-methylbutanoyl-CoA) is metabolized to 3-methylbut-2-enoyl-CoA. To a lesser extent, it also participates in the first step in fatty acid beta-oxidation, in which it catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of other saturated short-chain acyl-CoA thioesters such as pentanoyl-CoA, hexanoyl-CoA and butanoyl-CoA, using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor. {ECO:0000250|UniProtKB:P26440}.
uniprot
proteins
mass_dalton
46435
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3.
uniprot
proteins
protein_family
Acyl-CoA dehydrogenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2777793
uniprot
proteins
pubmed
3446585
uniprot
proteins
pubmed
6401713
uniprot
proteins
sequence_length
424
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:6401713}.
uniprot
proteins