Epb41
entrez
269587
canonical
uniprot
P48193
canonical
ensembl
ENSMUSG00000028906
resolver
ensp
ENSMUSP00000030739
resolver
ensp
ENSMUSP00000081274
resolver
ensp
ENSMUSP00000101601
resolver
ensp
ENSMUSP00000120236
resolver
ensp
ENSMUSP00000123623
resolver
ensp
ENSMUSP00000158714
resolver
ensp
ENSMUSP00000262316
resolver
ensp
ENSMUSP00000262317
resolver
ensp
ENSMUSP00000262318
resolver
ensp
ENSMUSP00000262319
resolver
ensp
ENSMUSP00000262320
resolver
ensp
ENSMUSP00000262321
resolver
ensp
ENSMUSP00000262322
resolver
ensp
ENSMUSP00000262324
resolver
ensp
ENSMUSP00000262326
resolver
enst
ENSMUST00000146021
resolver
genesymbol
Epb41
resolver
genesymbol_syn
Epb4.1
resolver
genesymbol_syn
Kiaa4056
resolver
uniprot
A0A068WAQ5
resolver
uniprot
A0A068WAZ7
resolver
uniprot
A0A571BEG4
resolver
uniprot
A2A843
resolver
uniprot
Q5DTQ8
resolver
uniprot
Q68FF1
resolver
uniprot
Q6NVF5
resolver
uniprot_entry
A0A068WAQ5_MOUSE
resolver
uniprot_entry
A0A068WAZ7_MOUSE
resolver
uniprot_entry
A0A571BEG4_MOUSE
resolver
uniprot_entry
EPB41_MOUSE
resolver
uniprot_sec
A2A843
resolver
uniprot_sec
Q5DTQ8
resolver
uniprot_sec
Q68FF1
resolver
uniprot_sec
Q6NVF5
resolver
amino_acid_sequence
MTTEKSLAAEAENSQHQQQKEEGEGATNSGQQETQLEEASQAAAAEGSDQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQVSEEEGREVESEKEKGEGGQKEIELGNSLDEDIILKAPIAAPEPELKTDPSLDLHSLSSIETQPAQEEHREDPDSETKEGEGIEECSGTEVKEDPESRAEREPEASQKPVRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLALWDSATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGMDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAAESTDRSPRPTSAPAIAQSQVTEGPGAPIKKTPKEAVKVEEKRGEEPAEPAEPEPTEAWKVEKTHTEVTVPTSNGDQTQKLAGKGEDLIRMRKKKRERLDGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQVPTGDGPPLVKTQTVTISDTANAVKSEIPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLTAQTITSETTSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE
uniprot
proteins
function
FUNCTION: Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. {ECO:0000250|UniProtKB:P11171}.
uniprot
proteins
mass_dalton
95911
uniprot
proteins
post_translational_modification
PTM: O-glycosylated; contains N-acetylglucosamine side chains in the C-terminal domain. {ECO:0000250}.; PTM: Phosphorylated at multiple sites by different protein kinases and each phosphorylation event selectively modulates the protein's functions.; PTM: Phosphorylation on Tyr-654 reduces the ability of 4.1 to promote the assembly of the spectrin/actin/4.1 ternary complex.
uniprot
proteins
pubmed
11432737
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17947660
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23460639
uniprot
proteins
pubmed
8429050
uniprot
proteins
sequence_length
858
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P11171}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P11171}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:P11171}.
uniprot
proteins