Mllt6
entrez
246198
canonical
uniprot
B1AR09
canonical
ensembl
ENSMUSG00000038437
resolver
ensp
ENSMUSP00000045445
resolver
ensp
ENSMUSP00000103212
resolver
enst
ENSMUST00000044730
resolver
enst
ENSMUST00000107586
resolver
genesymbol
Mllt6
resolver
genesymbol_syn
Af17
resolver
uniprot
B1AR10
resolver
uniprot
Q3UPK1
resolver
uniprot
Q8VHB4
resolver
uniprot_entry
AF17_MOUSE
resolver
uniprot_entry
B1AR10_MOUSE
resolver
uniprot_entry
Q3UPK1_MOUSE
resolver
uniprot_sec
Q8VHB4
resolver
amino_acid_sequence
MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMKTSRHSSGGGGGAGGGSSGGGGGGSSSASGGGGGTGGGSGNSFLSGRRSRSASPSTQPEKHPTHHEKGQKKSRKDKERLKQKHKKRPESPPSVLAPPAVPTADKVSSATSSSHHEASTQETSESSRDSKGRKSSSHSLSHKDKKLGTGKGSSLQSSPDFAAFPKLEQPEEDKYPKPADPTPPAPPSPTAPEPPKADLFEQKVVFSGFGPIMRFTTTASSSSRARAPSPGDYKSPHITGAGASAGTHKRMPALSATLGPAEEAPETTLKEKKHKASKRSRHGPGRPKGSRGKEGASGPTASLPAAQLAGFTATAASPFSGGSLVSAGLGGLASRTFGPSGSLPSLSLESSLLGAGIYTSNKDPISHGGGMLRAVCSTPLSSSLLGPTGTSALPRLSRSPFTSTLASSSASISTTQVFSLAGSTFSLPSSHIFGTPMGTVNPLLTQAESSHTEPDLEDCSFRCHGTSPQESLSSMSPISSLPALFDQTSAPCAGGQLDSTAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQVLNVQLSVPFPALPAALPATNGPIPGPYGLLPQAGSSDSLSVSKSPPGKNSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGATGLGAMPMAEGLLGGLAGSGSLPLNGLLGGLNGAAAPNPAGLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQMQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGSNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLPGADASGNGPKGGTADKGASTSQEKG
uniprot
proteins
function
FUNCTION: Involved in the stimulation of renal sodium reabsorption mediated by the epithelial sodium channel (ENaC) (PubMed:21546577). Up-regulates ENaC expression in renal collecting duct cells by promoting DOT1L export from the nucleus to the cytoplasm, thus limiting DOT1L-mediated H3K79 methylation and transcriptional repression at the SCNN1A promoter (PubMed:22087315). {ECO:0000269|PubMed:21546577, ECO:0000269|PubMed:22087315}.
uniprot
proteins
mass_dalton
110563
uniprot
proteins
pubmed
12438746
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21170927
uniprot
proteins
pubmed
21546577
uniprot
proteins
pubmed
22087315
uniprot
proteins
sequence_length
1079
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P55198}. Cytoplasm {ECO:0000250|UniProtKB:P55198}.
uniprot
proteins