Hhex
entrez
15242
canonical
uniprot
P43120
canonical
ensembl
ENSMUSG00000024986
resolver
ensp
ENSMUSP00000025944
resolver
enst
ENSMUST00000025944
resolver
genesymbol
Hhex
resolver
genesymbol_syn
Prh
resolver
genesymbol_syn
Prhx
resolver
uniprot
Q544N6
resolver
uniprot
Q9CRV1
resolver
uniprot
Q9R1X2
resolver
uniprot_entry
HHEX_MOUSE
resolver
uniprot_sec
Q544N6
resolver
uniprot_sec
Q9CRV1
resolver
uniprot_sec
Q9R1X2
resolver
amino_acid_sequence
MQFPHPGPAAAPAVGVPLYAPTPLLQPAHPTPFYIDDILGRGPAAPTPTPTLPSPNSSFTSLVSSYRTPVYEPTPVHPAFSHHPAAALAAAYGPSGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTVELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKDALDSLDTSCEQGQDLPSEQNKGASLDRSQCSPSPASQEDPDSEISEDSDQEVDIEGDKGYFNAG
uniprot
proteins
function
FUNCTION: Recognizes the DNA sequence 5'-ATTAA-3' (PubMed:10804173). Transcriptional repressor (PubMed:10804173). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:16936074). Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (PubMed:16936074). Inhibits EIF4E-mediated mRNA nuclear export (By similarity). May play a role in hematopoietic differentiation (PubMed:8096636). {ECO:0000250|UniProtKB:Q03014, ECO:0000269|PubMed:10804173, ECO:0000269|PubMed:16936074, ECO:0000269|PubMed:8096636}.
uniprot
proteins
mass_dalton
29987
uniprot
proteins
pubmed
10101294
uniprot
proteins
pubmed
10501975
uniprot
proteins
pubmed
10804173
uniprot
proteins
pubmed
12554669
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16936074
uniprot
proteins
pubmed
20028982
uniprot
proteins
pubmed
23665349
uniprot
proteins
pubmed
8096636
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23665349}. Nucleus, nuclear body {ECO:0000250|UniProtKB:Q03014}. Cytoplasm {ECO:0000250|UniProtKB:Q03014}.
uniprot
proteins