Phka2
entrez
110094
canonical
uniprot
Q8BWJ3
canonical
ensembl
ENSMUSG00000031295
resolver
ensp
ENSMUSP00000033652
resolver
ensp
ENSMUSP00000107995
resolver
ensp
ENSMUSP00000107996
resolver
ensp
ENSMUSP00000107999
resolver
ensp
ENSMUSP00000300414
resolver
enst
ENSMUST00000033652
resolver
enst
ENSMUST00000112376
resolver
enst
ENSMUST00000112377
resolver
enst
ENSMUST00000112380
resolver
genesymbol
Phka2
resolver
uniprot
A2AHQ7
resolver
uniprot
F6RY59
resolver
uniprot
Q3TN65
resolver
uniprot
Q6PE66
resolver
uniprot
Q810J6
resolver
uniprot_entry
A2AHQ7_MOUSE
resolver
uniprot_entry
F6RY59_MOUSE
resolver
uniprot_entry
KPB2_MOUSE
resolver
uniprot_entry
Q6PE66_MOUSE
resolver
uniprot_sec
Q3TN65
resolver
uniprot_sec
Q810J6
resolver
activity_regulation
ACTIVITY REGULATION: By phosphorylation of various serine residues and by calcium. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHDQKDAWVRDNIYSILAVWGLGMAYRKNADRDEDKAKAYELEQNVVKLMRGLLQCMMRQVDKVEKFKHTQSTKDSLHAKYNTATCSTVVGDDQWGHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIPELNASSVGVAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLLSIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPHRLHYDPAELKLFENIECEWPVFWTYLIIDGIFNGDAVQVQEYREALEGILIRGKDGIHLVPELYAIPPDKVDEEYKNPHTVDRVPLGKLPHLWGQSLYILSSLLAEGFLATGEIDPLNRRFSTSVKPDVVVQVAVLAENSHIKGLLKEHGMTVQSIADVHPIRVQPGRILSHIYAKLGRNKNMKLSGRPYRHIGVLGTSKLYVIRNHIFTFTPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPVTHTMLTNDGSDIHPAVLSTIRKLEDGYFGGARVKLGNLAEFLTTSFYTHLTFLDPDCDEKLFGDITDRSFSPDSEPDLGGYLEDSSPQESQDELDQYISHLLQSTSLKCYLPPLCKKSEDSHFFSAIHSTRDILSVMAKAKGLETTFFPMILPTKVLSGHRKSLNLVDSPQPLLKTTPEYDYQWPRDDHDEVDCEKLVGQLKDCSNLQDQADILYILYVMKGPRWDTNLFGQHGVTVHSLLSELYGKAGLNQEWSLIRYISGLLRKKVEVLAEACADLLSHQKQLTVGLPPEPREKTISTPLPPEELTELIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFAEMLRLRIGLIIQVMATELARSLNCSGKEASESLMNLSPFDMKSLLHHILSGKEFGVERSVRPIHSSMSSPAISIHEVGHTGATKTERSGITRLRSEMKQMNRRASADEQFFPLGQTMSNSLHSIKSVRSSTPSSPTGTSSTDSGGQHLGWGEQQGQWLRRRRLDGAINRVPVGFYQKVWKILQKCHGLSIDGYVLPSSTTQEMTPCEIKFAVHVESVLNRVSQPEYRQLLVEAIMVLTLLSDTEMDSIGGIIHVDQIVQLANQLFLQDQVSFGTTDILEKDQATGICHLFYDSAPSGAYGTMTYLTKAVASHLQELLPSSGCQMQ
uniprot
proteins
function
FUNCTION: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
uniprot
proteins
mass_dalton
138492
uniprot
proteins
pathway_participation
PATHWAY: Glycan biosynthesis; glycogen metabolism.
uniprot
proteins
post_translational_modification
PTM: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated. {ECO:0000250|UniProtKB:P18688}.
uniprot
proteins
protein_family
Phosphorylase b kinase regulatory chain family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1235
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins