LHFPL4
entrez
375323
canonical
uniprot
Q7Z7J7
canonical
ensembl
ENSG00000156959
resolver
ensp
ENSP00000287585
resolver
ensp
ENSP00000525018
resolver
enst
ENST00000287585
resolver
enst
ENST00000854959
resolver
genesymbol
LHFPL4
resolver
genesymbol_syn
GARLH4
resolver
hgnc
HGNC:29568
resolver
uniprot
A6NH76
resolver
uniprot
Q29RV7
resolver
uniprot_entry
LHPL4_HUMAN
resolver
uniprot_sec
A6NH76
resolver
uniprot_sec
Q29RV7
resolver
amino_acid_sequence
MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLRPGGDVSGWGVLPCPVAHSQGP
uniprot
proteins
function
FUNCTION: Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites. Acts in concert with NLGN2 to recruit or stabilize GABAARs. {ECO:0000250|UniProtKB:Q5U4E0}.
uniprot
proteins
mass_dalton
27007
uniprot
proteins
protein_family
LHFP family
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
28978485
uniprot
proteins
sequence_length
247
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, dendrite {ECO:0000250|UniProtKB:Q7TSY2}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q5U4E0}; Multi-pass membrane protein {ECO:0000255}. Note=Specifically localizes to inhibitory postsynaptic sites (By similarity). Colocalizes with GPHN, GABRG2 and NLGN2 at inhibitory postsynaptic sites (By similarity). {ECO:0000250|UniProtKB:Q5U4E0, ECO:0000250|UniProtKB:Q7TSY2}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 97..117; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 127..147; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 178..198; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins