SFXN5
entrez
94097
canonical
uniprot
Q8TD22
canonical
ensembl
ENSG00000144040
resolver
ensp
ENSP00000272433
resolver
ensp
ENSP00000387076
resolver
ensp
ENSP00000402141
resolver
ensp
ENSP00000538654
resolver
ensp
ENSP00000608247
resolver
ensp
ENSP00000652324
resolver
ensp
ENSP00000652326
resolver
ensp
ENSP00000652335
resolver
ensp
ENSP00000730983
resolver
enst
ENST00000272433
resolver
enst
ENST00000410065
resolver
genesymbol
SFXN5
resolver
hgnc
HGNC:16073
resolver
uniprot
A8K116
resolver
uniprot
B4DIJ8
resolver
uniprot
B8ZZJ6
resolver
uniprot
Q494Y3
resolver
uniprot
Q53T29
resolver
uniprot_entry
B4DIJ8_HUMAN
resolver
uniprot_entry
B8ZZJ6_HUMAN
resolver
uniprot_entry
SFXN5_HUMAN
resolver
uniprot_sec
A8K116
resolver
uniprot_sec
Q494Y3
resolver
uniprot_sec
Q53T29
resolver
amino_acid_sequence
MADTATTASAAAASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVQSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIAQATSSRTVVYNKGL
uniprot
proteins
function
FUNCTION: Mitochondrial amino-acid transporter (By similarity). Transports citrate (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity) (PubMed:30442778). In brown adipose tissue, plays a role in the regulation of UCP1-dependent thermogenesis probably by supporting mitochondrial glycerol-3-phosphate utilization (By similarity). {ECO:0000250|UniProtKB:Q8CFD0, ECO:0000250|UniProtKB:Q925N0, ECO:0000250|UniProtKB:Q9H9B4, ECO:0000269|PubMed:30442778}.
uniprot
proteins
mass_dalton
37124
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
12039050
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
30442778
uniprot
proteins
sequence_length
340
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:30442778}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 103..123; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 163..183; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 254..274; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 287..307; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins