Thumpd3
entrez
14911
canonical
uniprot
P97770
canonical
ensembl
ENSMUSG00000030264
resolver
ensp
ENSMUSP00000032398
resolver
ensp
ENSMUSP00000178088
resolver
ensp
ENSMUSP00000178093
resolver
ensp
ENSMUSP00000178099
resolver
ensp
ENSMUSP00000178102
resolver
genesymbol
Thumpd3
resolver
uniprot
Q99M45
resolver
uniprot
Q9D3P0
resolver
uniprot_entry
THUM3_MOUSE
resolver
uniprot_sec
Q99M45
resolver
uniprot_sec
Q9D3P0
resolver
amino_acid_sequence
MSCDTQEATRECLGMNLDGNKEPVSLVESGVRSESEHLQVTIGATVPTGFEQTAAGEVREKLKSACRISKDRGKIYFDIAVESLAQVHCLRSVDNLFVVVQEFKDYQFKDTKEEVLRDFEELAGKLPWSDPLKVWQINTTFKKKKAKRRKANQSAGKEKADCGQGDKADEKDGKKKHASSTSDSHILDYYENPAIKEEISTLVGDVLSSCKDETGQSLREETEPQVQKFRVTCNRAGEKHCFTSNEAARDFGGAIQEYFKWKADMTNFDVEVLLNIHDNEVIVAIALTEESLHRRNITHFGPTTLRSTLAYGMLRLCEPKPTDVIVDPMCGTGAIPIEGATEWSHCYHIAGDNNPLAVNRAANNISSLLTKSQIKDGKTTWGLPIDAVQWDICNLPLRTASVDIIVTDMPFGKRMGSKKRNWNLYPACLREMSRVCRPGTGRAVLLTQDKKCFTKALSGMGHVWRKVHVVWVNIGGLHAAVYLLKRTAQAFVHPSDQDEGRDPPW
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
ec_number
2.1.1.256
uniprot
proteins
function
FUNCTION: Catalytic subunit of the THUMPD3-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 6 (m2G6) in tRNAs. This is one of the major tRNA (guanine-N(2))-methyltransferases. Also catalyzes the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 7 of tRNA(Trp). {ECO:0000250|UniProtKB:Q9BV44}.
uniprot
proteins
mass_dalton
56431
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
34669960
uniprot
proteins
pubmed
9108056
uniprot
proteins
sequence_length
505
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BV44}.
uniprot
proteins