Doc2a
entrez
13446
canonical
uniprot
Q7TNF0
canonical
ensembl
ENSMUSG00000052301
resolver
ensp
ENSMUSP00000070119
resolver
ensp
ENSMUSP00000202358
resolver
ensp
ENSMUSP00000202362
resolver
ensp
ENSMUSP00000202363
resolver
ensp
ENSMUSP00000202372
resolver
enst
ENSMUST00000064110
resolver
genesymbol
Doc2a
resolver
uniprot_entry
DOC2A_MOUSE
resolver
amino_acid_sequence
MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRRGPGPEGGGGGGGTGCGEAPAHLAPLALAPPAALLGATTPDDGAEVDSYDSDDTTALGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEAQKHWNDCLHQPDTALERWHTLTSELPPAAGAYPLA
uniprot
proteins
function
FUNCTION: Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. {ECO:0000269|PubMed:18354201, ECO:0000269|PubMed:20150444}.
uniprot
proteins
mass_dalton
44609
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18354201
uniprot
proteins
pubmed
20150444
uniprot
proteins
sequence_length
405
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Synapse, synaptosome {ECO:0000250}. Lysosome {ECO:0000250}.
uniprot
proteins