Gigyf1
entrez
57330
canonical
uniprot
Q99MR1
canonical
ensembl
ENSMUSG00000029714
resolver
ensp
ENSMUSP00000031727
resolver
enst
ENSMUST00000031727
resolver
genesymbol
Gigyf1
resolver
genesymbol_syn
Kiaa4110
resolver
genesymbol_syn
Perq1
resolver
uniprot
Q571A0
resolver
uniprot
Q6Y7W9
resolver
uniprot_entry
GGYF1_MOUSE
resolver
uniprot_sec
Q571A0
resolver
uniprot_sec
Q6Y7W9
resolver
amino_acid_sequence
MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLPATSRGRGSTRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDDRGERRFEKPARRDGVRSGFEEGGAGPRKEHARSDSENWRSLREEQEDDGSWRLGAGPRRDGDRWRSTSPDGGPRSAGWREHGERRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRGLDGFEDDKDGLPEWCLEDEDEEMGTFDASGAFLPLKKGPKEAIPEEQELDFRGLEEEEEEEEEPSEGVDEERPEAGGKEATPLPPPENSSSPSSLPALGPLWTTNEEGGEAVEKELPPAEGDELRGLSLSPRISSPPGPPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQHFLQLVGSRQLPQCTTLREKAAMGDLTPPQQQQLTTFLQQLQALKTPRGGDQNLLPTMSRSLSVPDSGPLWDLHTSASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRRQQQQQQEEQKRRQEEEELFRRKQVRQQELLLKLLQQQQATNVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQMESERQLHKQAAPREPLRAQAPNHRVQLGGLGSAPLNQWVSEAGPLWGGPDKSGGSSGGNLGLWEDTLKSGGSLARSLGLKSSRSSPSLSDSYSHLSGRPVRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTAGSLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQEAWLSSTSLQTAFQANHSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGPSGEIESVDDY
uniprot
proteins
function
FUNCTION: May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1. {ECO:0000269|PubMed:12771153}.
uniprot
proteins
mass_dalton
116238
uniprot
proteins
mutagenesis
MUTAGEN 500; /note="W->A: Decreases binding to GRB10."; /evidence="ECO:0000269|PubMed:12771153"; MUTAGEN 504; /note="G->A: Decreases binding to GRB10."; /evidence="ECO:0000269|PubMed:12771153"; MUTAGEN 505; /note="Y->A: Decreases binding to GRB10."; /evidence="ECO:0000269|PubMed:12771153"; MUTAGEN 506; /note="F->A: Abolishes binding to GRB10."; /evidence="ECO:0000269|PubMed:12771153
uniprot
proteins
protein_family
GIGYF family
uniprot
proteins
pubmed
11239002
uniprot
proteins
pubmed
12771153
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1044
uniprot
proteins