Henmt1
entrez
100363095
canonical
uniprot
Q32PY6
canonical
ensembl
ENSRNOG00000042814
resolver
ensp
ENSRNOP00000060946
resolver
ensp
ENSRNOP00000095551
resolver
enst
ENSRNOT00000066924
resolver
genesymbol
Henmt1
resolver
uniprot
F1LQ15
resolver
uniprot_entry
F1LQ15_RAT
resolver
uniprot_entry
HENMT_RAT
resolver
amino_acid_sequence
METAENIPCSMLGDNFKEVCAEKVIRFRPPLYKQRYQFVRDLVDRHEPKKVADLGCGDTKLLKLLKIYPCIQLLVGVDINEEKLHSNGHRLSPYLGEFVKPRDLDLTVTLYHGSVVERDSRLLGFDLITCIELIEHLDSDDLARFPEVVFGYLSPAMVVISTPNAEFNPLFPTVTLRDADHKFEWSRMEFQTWASQVANCYNYCVEFTGVGTPPAGSEHVGYCTQIGVFRKNGGKLSEPSASQQRDQHVYKAVYTTSYPSLQQEKVLKFVLVGELLIQVDRLRLRHQRMLREQEKERGPKPWYTDSSPAPHLLLGAVFTEAEKARIENSPKPFCEGEKFYIPLQRLLTYPKLHRLCADEDRMRSLIADSVCLSSDGSAVVVDLHNSWDYRPEDN
uniprot
proteins
ec_number
2.1.1.386
uniprot
proteins
function
FUNCTION: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. {ECO:0000250|UniProtKB:Q8CAE2}.
uniprot
proteins
mass_dalton
45087
uniprot
proteins
protein_family
HEN1 family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
394
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q568P9}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250|UniProtKB:Q568P9}.
uniprot
proteins