F3
entrez
14066
canonical
uniprot
P20352
canonical
ensembl
ENSMUSG00000028128
resolver
ensp
ENSMUSP00000029771
resolver
enst
ENSMUST00000029771
resolver
genesymbol
F3
resolver
genesymbol_syn
Cf-3
resolver
genesymbol_syn
Cf3
resolver
uniprot
A0A0R4J088
resolver
uniprot_entry
A0A0R4J088_MOUSE
resolver
uniprot_entry
TF_MOUSE
resolver
amino_acid_sequence
MAILVRPRLLAALAPTFLGCLLLQVIAGAGIPEKAFNLTWISTDFKTILEWQPKPTNYTYTVQISDRSRNWKNKCFSTTDTECDLTDEIVKDVTWAYEAKVLSVPRRNSVHGDGDQLVIHGEEPPFTNAPKFLPYRDTNLGQPVIQQFEQDGRKLNVVVKDSLTLVRKNGTFLTLRQVFGKDLGYIITYRKGSSTGKKTNITNTNEFSIDVEEGVSYCFFVQAMIFSRKTNQNSPGSSTVCTEQWKSFLGETLIIVGAVVLLATIFIILLSISLCKRRKNRAGQKGKNTPSRLA
uniprot
proteins
function
FUNCTION: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
uniprot
proteins
mass_dalton
32935
uniprot
proteins
protein_family
Tissue factor family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19656770
uniprot
proteins
pubmed
1985911
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23291174
uniprot
proteins
pubmed
2761539
uniprot
proteins
sequence_length
294
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:P13726}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P13726}.
uniprot
proteins
transmembrane_region
TRANSMEM 252..274; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins