CPSF4
entrez
10898
canonical
uniprot
O95639
canonical
ensembl
ENSG00000160917
resolver
ensp
ENSP00000292476
resolver
ensp
ENSP00000395311
resolver
ensp
ENSP00000402224
resolver
ensp
ENSP00000557847
resolver
ensp
ENSP00000700139
resolver
ensp
ENSP00000781518
resolver
enst
ENST00000441580
resolver
genesymbol
CPSF4
resolver
genesymbol_syn
CPSF30
resolver
genesymbol_syn
NAR
resolver
genesymbol_syn
NEB1
resolver
hgnc
HGNC:2327
resolver
uniprot
B7Z7B0
resolver
uniprot
D6W5S8
resolver
uniprot
F6S9K0
resolver
uniprot
Q6FGE6
resolver
uniprot
Q86TF8
resolver
uniprot
Q9BTW6
resolver
uniprot_entry
B7Z7B0_HUMAN
resolver
uniprot_entry
CPSF4_HUMAN
resolver
uniprot_entry
F6S9K0_HUMAN
resolver
uniprot_sec
D6W5S8
resolver
uniprot_sec
Q6FGE6
resolver
uniprot_sec
Q86TF8
resolver
uniprot_sec
Q9BTW6
resolver
amino_acid_sequence
MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ
uniprot
proteins
function
FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). {ECO:0000269|PubMed:14749727, ECO:0000269|PubMed:9224719}.
uniprot
proteins
mass_dalton
30255
uniprot
proteins
protein_family
CPSF4/YTH1 family
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
14749727
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21102410
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
9224719
uniprot
proteins
pubmed
9651582
uniprot
proteins
sequence_length
269
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins