Akr7a2
entrez
171445
canonical
uniprot
Q8CG45
canonical
ensembl
ENSRNOG00000017780
resolver
ensembl
ENSRNOG00055023191
resolver
ensembl
ENSRNOG00060027035
resolver
ensembl
ENSRNOG00065022270
resolver
ensp
ENSRNOP00000072789
resolver
ensp
ENSRNOP00055032343
resolver
ensp
ENSRNOP00060038995
resolver
ensp
ENSRNOP00065030718
resolver
enst
ENSRNOT00000083629
resolver
enst
ENSRNOT00055039859
resolver
enst
ENSRNOT00060046893
resolver
enst
ENSRNOT00065037964
resolver
genesymbol
Akr7a2
resolver
genesymbol_syn
Afar2
resolver
genesymbol_syn
Aiar
resolver
uniprot
A0A0G2K3V2
resolver
uniprot
Q6P765
resolver
uniprot
Q8K435
resolver
uniprot
Q9JM82
resolver
uniprot_entry
A0A0G2K3V2_RAT
resolver
uniprot_entry
ARK72_RAT
resolver
uniprot_sec
Q6P765
resolver
uniprot_sec
Q8K435
resolver
uniprot_sec
Q9JM82
resolver
amino_acid_sequence
MLRAVSRAVSRAAVRCAWRSGPSVARPLAMSRSPAPRAVSGAPLRPGTVLGTMEMGRRMDASASAATVRAFLERGLNELDTAFMYCDGQSESILGSLGLGLGSGDCTVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPRVDLFYLHAPDHGTPIVETLQACQQLHQEGKFVELGLSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETELLPCLRYFGLRFYAYNPLAGGLLTGKYRYEDKDGKQPEGRFFGNSWSETYRNRFWKEHHFEAIALVEKALKTTYGTSAPSMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLEPAVVEAFNQAWNVVAHECPNYFR
uniprot
proteins
ec_number
1.1.1.n11
uniprot
proteins
function
FUNCTION: Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. Acts as a 2-carboxybenzaldehyde reductase. {ECO:0000269|PubMed:12071861}.
uniprot
proteins
mass_dalton
40675
uniprot
proteins
protein_family
Aldo/keto reductase 2 subfamily
uniprot
proteins
protein_family
Aldo/keto reductase family
uniprot
proteins
pubmed
10965890
uniprot
proteins
pubmed
12071861
uniprot
proteins
pubmed
12879023
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
367
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:12071861}. Cytoplasm {ECO:0000269|PubMed:12071861}. Note=Its association with the Golgi stack may facilitate secretion of GHB. {ECO:0000303|PubMed:12071861}.
uniprot
proteins