Fbxl22
entrez
74165
canonical
uniprot
Q8C7B6
canonical
ensembl
ENSMUSG00000050503
resolver
ensp
ENSMUSP00000060137
resolver
enst
ENSMUST00000056890
resolver
genesymbol
Fbxl22
resolver
uniprot
Q8C3G3
resolver
uniprot
Q8C3V6
resolver
uniprot_entry
FXL22_MOUSE
resolver
uniprot_sec
Q8C3G3
resolver
uniprot_sec
Q8C3V6
resolver
amino_acid_sequence
MHITQLNRECLLCLFSFLDKDSRRSLSRTCSQLRDVFEDPTLWPLLHFHSLAELKKDNFRLSPALRSLSICWHSSRVQVCSIEDWLKSALQRSICSQHESLVNDFLLQVCNRCPNLTSVTLSGCGHVTDDCLARLLLSCPRLRTLRLENCARVTNRTLAAVAAHGRALQTLHVDFCRNVSAAGLLRLRAACPNLRLSAERSAAMIPDQPPRARVCAASAFSAAPGRQSMPHPTGSY
uniprot
proteins
function
FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC) (By similarity). {ECO:0000250|UniProtKB:Q6P050}.
uniprot
proteins
mass_dalton
26320
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:Q6P050}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
22972877
uniprot
proteins
sequence_length
236
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:22972877}.
uniprot
proteins