Grik1
entrez
29559
canonical
uniprot
P22756
canonical
ensembl
ENSRNOG00000001575
resolver
ensp
ENSRNOP00000045594
resolver
ensp
ENSRNOP00000046164
resolver
ensp
ENSRNOP00000050263
resolver
ensp
ENSRNOP00000078137
resolver
ensp
ENSRNOP00000105903
resolver
enst
ENSRNOT00000042581
resolver
enst
ENSRNOT00000050073
resolver
enst
ENSRNOT00000051060
resolver
enst
ENSRNOT00000147508
resolver
genesymbol
Grik1
resolver
genesymbol_syn
Glur5
resolver
uniprot
A0A140TAF9
resolver
uniprot
A0A140TAG6
resolver
uniprot
A0ABK0LJK6
resolver
uniprot
F1M7M9
resolver
uniprot_entry
A0A140TAF9_RAT
resolver
uniprot_entry
A0A140TAG6_RAT
resolver
uniprot_entry
A0ABK0LJK6_RAT
resolver
uniprot_entry
F1M7M9_RAT
resolver
uniprot_entry
GRIK1_RAT
resolver
amino_acid_sequence
MERSTVLIQPGLWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDSRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRKLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPCALGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEAYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGKSSRLRFYFRNKVRFHGSKKESLGVEKCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA
uniprot
proteins
function
FUNCTION: Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. {ECO:0000269|PubMed:11425885, ECO:0000269|PubMed:12873388, ECO:0000269|PubMed:1322826, ECO:0000269|PubMed:1373382, ECO:0000269|PubMed:16540562, ECO:0000269|PubMed:1977421, ECO:0000269|PubMed:25139762, ECO:0000269|PubMed:9254673}.
uniprot
proteins
mass_dalton
107840
uniprot
proteins
protein_family
GRIK1 subfamily
uniprot
proteins
protein_family
Glutamate-gated ion channel (TC 1.A.10.1) family
uniprot
proteins
pubmed
10023812
uniprot
proteins
pubmed
11425885
uniprot
proteins
pubmed
12873388
uniprot
proteins
pubmed
1322826
uniprot
proteins
pubmed
1373382
uniprot
proteins
pubmed
15710405
uniprot
proteins
pubmed
15721240
uniprot
proteins
pubmed
16540562
uniprot
proteins
pubmed
17062563
uniprot
proteins
pubmed
1977421
uniprot
proteins
pubmed
25139762
uniprot
proteins
pubmed
9254673
uniprot
proteins
sequence_length
949
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:10023812}; Multi-pass membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000305|PubMed:10023812}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 577..597; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 654..674; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 835..855; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins