TMEM9B
entrez
56674
canonical
uniprot
Q9NQ34
canonical
ensembl
ENSG00000175348
resolver
ensp
ENSP00000311842
resolver
ensp
ENSP00000431487
resolver
ensp
ENSP00000433361
resolver
genesymbol
TMEM9B
resolver
genesymbol_syn
C11orf15
resolver
hgnc
HGNC:1168
resolver
uniprot
B7Z6P5
resolver
uniprot
Q543A1
resolver
uniprot
Q7Z649
resolver
uniprot_entry
B7Z6P5_HUMAN
resolver
uniprot_entry
Q543A1_HUMAN
resolver
uniprot_entry
TMM9B_HUMAN
resolver
uniprot_sec
Q7Z649
resolver
amino_acid_sequence
MATLWGGLLRLGSLLSLSCLALSVLLLAQLSDAAKNFEDVRCKCICPPYKENSGHIYNKNISQKDCDCLHVVEPMPVRGPDVEAYCLRCECKYEERSSVTIKVTIIIYLSILGLLLLYMVYLTLVEPILKRRLFGHAQLIQSDDDIGDHQPFANAHDVLARSRSRANVLNKVEYAQQRWKLQVQEQRKSVFDRHVVLS
uniprot
proteins
function
FUNCTION: Enhances production of pro-inflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways. {ECO:0000269|PubMed:18541524}.
uniprot
proteins
mass_dalton
22531
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:18541524}.
uniprot
proteins
protein_family
TMEM9 family
uniprot
proteins
pubmed
11528127
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
18541524
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000269|PubMed:18541524}; Single-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000269|PubMed:18541524}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 105..125; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins