Ilrun
entrez
224647
canonical
uniprot
Q3TT38
canonical
ensembl
ENSMUSG00000056692
resolver
ensp
ENSMUSP00000110509
resolver
ensp
ENSMUSP00000110513
resolver
ensp
ENSMUSP00000156684
resolver
enst
ENSMUST00000114859
resolver
enst
ENSMUST00000114863
resolver
enst
ENSMUST00000233508
resolver
genesymbol
Ilrun
resolver
genesymbol_syn
D17Wsu92e
resolver
uniprot
A0A3B2WCT9
resolver
uniprot
A2RT11
resolver
uniprot
B2KF54
resolver
uniprot
B2RPS0
resolver
uniprot_entry
A0A3B2WCT9_MOUSE
resolver
uniprot_entry
B2KF54_MOUSE
resolver
uniprot_entry
B2RPS0_MOUSE
resolver
uniprot_entry
ILRUN_MOUSE
resolver
uniprot_sec
A2RT11
resolver
amino_acid_sequence
MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIGAYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFIKTWRIQNSGAEAWPPGVCLKYVGGDQFGHVNMVMVRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLTDPGGSEFDSISKNTWAPVPEQSEQDQDRLSQSSVNLSPSSPANNLSVVTYSKGLHGPYPFGQS
uniprot
proteins
function
FUNCTION: Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF. Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP. {ECO:0000250|UniProtKB:Q9H6K1}.
uniprot
proteins
mass_dalton
32082
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H6K1}. Nucleus {ECO:0000250|UniProtKB:Q9H6K1}.
uniprot
proteins