Sec14l1
entrez
74136
canonical
uniprot
A8Y5H7
canonical
ensembl
ENSMUSG00000020823
resolver
ensp
ENSMUSP00000021177
resolver
ensp
ENSMUSP00000087916
resolver
ensp
ENSMUSP00000099315
resolver
genesymbol
Sec14l1
resolver
genesymbol_syn
Kiaa4251
resolver
uniprot
A2A9B9
resolver
uniprot
Q6A071
resolver
uniprot
Q99J07
resolver
uniprot
Q9DBQ0
resolver
uniprot_entry
S14L1_MOUSE
resolver
uniprot_sec
A2A9B9
resolver
uniprot_sec
Q6A071
resolver
uniprot_sec
Q99J07
resolver
uniprot_sec
Q9DBQ0
resolver
amino_acid_sequence
MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVSEFKSEDGALHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNSRDRTLHIEAHNETFSNRVIIHEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKHYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPPVGPSETCSSSKNQVTSAAVLVPDAAAVMEGLSGENLSSPGTASEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQVLLDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCDVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHTMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSQSSSMISR
uniprot
proteins
function
FUNCTION: May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of RIGI, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of RIGI with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters. {ECO:0000250|UniProtKB:Q92503}.
uniprot
proteins
mass_dalton
81216
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
715
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q92503}. Golgi apparatus {ECO:0000250|UniProtKB:Q92503}.
uniprot
proteins