Frk
entrez
14302
canonical
uniprot
Q922K9
canonical
ensembl
ENSMUSG00000019779
resolver
ensp
ENSMUSP00000019913
resolver
ensp
ENSMUSP00000130289
resolver
ensp
ENSMUSP00000229055
resolver
ensp
ENSMUSP00000229056
resolver
enst
ENSMUST00000019913
resolver
enst
ENSMUST00000170771
resolver
genesymbol
Frk
resolver
genesymbol_syn
Bsk
resolver
genesymbol_syn
Iyk
resolver
uniprot
Q61364
resolver
uniprot
Q61745
resolver
uniprot_entry
FRK_MOUSE
resolver
uniprot_sec
Q61364
resolver
uniprot_sec
Q61745
resolver
amino_acid_sequence
MGSVCVRLWAYLQPFLPCWSQEADKSVVIENPGAFCPPEAPRSQEPERSHGQYFVALFDYQARTAEDLSFRAGDKLQVLDTSHEGWWLARHLEKKGTGLGQQLQGYIPSNYVAEDRSLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEGVVKHYRIRRLDEGGFFLTRRKVFSTLNEFVNYYTTTSDGLCVKLEKPCLKIQVPTPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFETLHWKLEDYFETDCSYSDTNNFIN
uniprot
proteins
ec_number
2.7.10.2
uniprot
proteins
function
FUNCTION: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
58844
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
SRC subfamily
uniprot
proteins
protein_family
Tyr protein kinase family
uniprot
proteins
pubmed
12077350
uniprot
proteins
pubmed
15186217
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7733928
uniprot
proteins
pubmed
7835707
uniprot
proteins
sequence_length
512
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery. {ECO:0000250}.
uniprot
proteins