NRBP1
entrez
29959
canonical
uniprot
Q9UHY1
canonical
ensembl
ENSG00000115216
resolver
ensp
ENSP00000233557
resolver
ensp
ENSP00000369181
resolver
ensp
ENSP00000369192
resolver
ensp
ENSP00000527604
resolver
ensp
ENSP00000527605
resolver
ensp
ENSP00000527611
resolver
ensp
ENSP00000527612
resolver
ensp
ENSP00000593255
resolver
ensp
ENSP00000625692
resolver
enst
ENST00000233557
resolver
enst
ENST00000379852
resolver
enst
ENST00000379863
resolver
enst
ENST00000857545
resolver
enst
ENST00000857552
resolver
enst
ENST00000857553
resolver
enst
ENST00000923196
resolver
enst
ENST00000955633
resolver
genesymbol
NRBP1
resolver
genesymbol_syn
BCON3
resolver
genesymbol_syn
NRBP
resolver
hgnc
HGNC:7993
resolver
uniprot
B3KV40
resolver
uniprot
D6W558
resolver
uniprot
F8W6G1
resolver
uniprot
Q53FZ5
resolver
uniprot
Q96SU3
resolver
uniprot_entry
F8W6G1_HUMAN
resolver
uniprot_entry
NRBP_HUMAN
resolver
uniprot_sec
B3KV40
resolver
uniprot_sec
D6W558
resolver
uniprot_sec
Q53FZ5
resolver
uniprot_sec
Q96SU3
resolver
amino_acid_sequence
MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS
uniprot
proteins
function
FUNCTION: Required for embryonic development (By similarity). Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes (By similarity). May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases (PubMed:11956649). Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication (PubMed:15084397). {ECO:0000250|UniProtKB:Q99J45, ECO:0000269|PubMed:11956649, ECO:0000269|PubMed:15084397}.
uniprot
proteins
mass_dalton
59845
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
10843813
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11956649
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15084397
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
18088087
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22510880
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cell cortex {ECO:0000269|PubMed:11956649}. Endomembrane system {ECO:0000269|PubMed:11956649}. Cell projection, lamellipodium {ECO:0000269|PubMed:11956649}. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
uniprot
proteins