Tbc1d32
entrez
544696
canonical
uniprot
Q3URV1
canonical
ensembl
ENSMUSG00000038122
resolver
ensp
ENSMUSP00000097328
resolver
ensp
ENSMUSP00000316071
resolver
genesymbol
Tbc1d32
resolver
genesymbol_syn
Bromi
resolver
uniprot_entry
BROMI_MOUSE
resolver
amino_acid_sequence
MAHFSSEDEVMLQAMLRQLFQSVKEKITGAPSLECAEEILLRLEETDENFHNYEFVKYLRQHICNMLGSMIEEEMEKCTSDQNQGEDSGYDTVVQHVTKRTQESKEYKEMMHSLKNIMMVVVEAMINKFEEDETRSEDRQRKMQSGSCCTDNCSDSDSSFNQSYKFCQGKLRLILDQLDPGQPKEVRYEALQTLCSAPPSDVLSCENWTTLCEKLTTSLSDPDPMFTDRILKFYAQTFTLSPLHMTKEIYTSLAKYLEVYFLSRENHLPTLSTGVDITSPNVTRLLKKVRLLNEYQKEAPSFWIRHPEKYMEEIVESTLSLLSVKHEQSHLVPQKILDPIYFFALVDTKAVWFKKWMHAYYSRTAVLRLLEKKYKCLITTAVQQCVQYLELCEAMKADEILRHPKHCGTKQKSFYYSGQELQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRKDSVSLTNLLVLFTQLIYYSPSCPKMTSIMCSENYSPASMVTDVLRMLCDQKECAVECLYNSTVTEALLLPIHNLTKGTAAAPDCSETALIHIADILARIASVEEGLILLLYGENMNSSEEESLTGAHIIAKFSKKLLEEDISIFSGSEMLPVVKGAFISVCRQIYGTCEGLQVLLPYGLHESIAKAWKKTSLLSERIPTPVEGSDSVSSVSQVSPNSVAWEDNLLDDLLNFAATPKGLLLLQRTGAINECVTFMLSQYAKKPQVNRQKKFGYEVLVVQVASTAAGAVALQNSGFISALITELWSNLECGRDDVRLTHPRATPVDPIDRSCQKSFLALVNLLSYPAVYELTANQELPNKAEYSLREVPTCIIDIMDRLIVLNSEAKIRSLLNYEQSHTFGLRLLSVVCCDLDALLLLEAQYQVSNMLLHAQEENTFEISENHRNFIIDGLSVERNHVLVRINLIGGPSERILPPRMLEKGDDPYPWPMFSSYPLPHCYQSEGPRSADLKQDNDIGNLLSCFKMSDKQTEWIENCRRQFCKTMKSKPDAVHGSALGELLEKFVLLLTENPSECYFPSVEYTATDANVKNESLSSVQQLGMKMTVRYGRFLNLLKDGAENELALVLKHCEKFLKQQQSPVTSSLLCLQGNYAGHDWFVSSLFMIMLGDKGKTFHFLQHFSRLLTSAFLWVPRLHNSRYLPVDTLGTGIHPIYFCSAHYIEMLLKAEVPLVFSAFHMSGFAPSQICLQWITQCFWNYLDWIEICHYIATCVVLGPDYQVYVCIAVLKHLQRDILQHTQTQDLQVFLKEEALHGFRVSNYFEYMENLEQNYRPVLLRDMRSIRVQNT
uniprot
proteins
function
FUNCTION: Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling. {ECO:0000269|PubMed:20159594}.
uniprot
proteins
mass_dalton
148061
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20159594
uniprot
proteins
sequence_length
1296
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20159594}. Cell projection, cilium {ECO:0000269|PubMed:20159594}.
uniprot
proteins