MTCH1
entrez
23787
canonical
uniprot
Q9NZJ7
canonical
ensembl
ENSG00000137409
resolver
ensp
ENSP00000362718
resolver
ensp
ENSP00000362730
resolver
ensp
ENSP00000419739
resolver
ensp
ENSP00000511680
resolver
enst
ENST00000460219
resolver
enst
ENST00000695073
resolver
genesymbol
MTCH1
resolver
genesymbol
PIG60
resolver
genesymbol_syn
PSAP
resolver
hgnc
HGNC:17586
resolver
uniprot
A0A8Q3WKC8
resolver
uniprot
A8KAX5
resolver
uniprot
A8YXX5
resolver
uniprot
B2RCE3
resolver
uniprot
H0Y8C3
resolver
uniprot
Q6PK60
resolver
uniprot
Q6UX45
resolver
uniprot
Q7L465
resolver
uniprot
Q9BW23
resolver
uniprot
Q9NZR6
resolver
uniprot
Q9UJZ5
resolver
uniprot_entry
A0A8Q3WKC8_HUMAN
resolver
uniprot_entry
A8YXX5_HUMAN
resolver
uniprot_entry
H0Y8C3_HUMAN
resolver
uniprot_entry
MTCH1_HUMAN
resolver
uniprot_sec
A8KAX5
resolver
uniprot_sec
B2RCE3
resolver
uniprot_sec
Q6PK60
resolver
uniprot_sec
Q6UX45
resolver
uniprot_sec
Q7L465
resolver
uniprot_sec
Q9BW23
resolver
uniprot_sec
Q9NZR6
resolver
uniprot_sec
Q9UJZ5
resolver
amino_acid_sequence
MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGSGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE
uniprot
proteins
function
FUNCTION: Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins (By similarity). Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). May play a role in apoptosis (PubMed:12377771). {ECO:0000250|UniProtKB:Q9Y6C9, ECO:0000269|PubMed:12377771, ECO:0000269|PubMed:36264797}.
uniprot
proteins
mass_dalton
41544
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
10551805
uniprot
proteins
pubmed
12377771
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
36264797
uniprot
proteins
pubmed
40105103
uniprot
proteins
sequence_length
389
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000305|PubMed:12377771}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 94..104; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 156..176; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 210..229; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 255..279; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 323..342; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 372..389; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins