COMMD9
entrez
29099
canonical
uniprot
Q9P000
canonical
ensembl
ENSG00000110442
resolver
ensp
ENSP00000263401
resolver
ensp
ENSP00000392510
resolver
ensp
ENSP00000435599
resolver
enst
ENST00000532705
resolver
genesymbol
COMMD9
resolver
hgnc
HGNC:25014
resolver
uniprot
E9PAN2
resolver
uniprot
E9PJ95
resolver
uniprot
Q53FR9
resolver
uniprot
Q96FI2
resolver
uniprot
Q9H0R0
resolver
uniprot_entry
COMD9_HUMAN
resolver
uniprot_entry
E9PJ95_HUMAN
resolver
uniprot_entry
Q53FR9_HUMAN
resolver
uniprot_sec
E9PAN2
resolver
uniprot_sec
Q96FI2
resolver
uniprot_sec
Q9H0R0
resolver
amino_acid_sequence
MAALTAEHFAALQSLLKASSKDVVRQLCQESFSSSALGLKKLLDVTCSSLSVTQEEAEELLQALHRLTRLVAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKETLDTMLDGLGRIRDQLSAVASK
uniprot
proteins
function
FUNCTION: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203). {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:23637203, ECO:0000269|PubMed:37172566, ECO:0000269|PubMed:38459129, ECO:0000305|PubMed:21778237}.
uniprot
proteins
mass_dalton
21819
uniprot
proteins
protein_family
COMM domain-containing protein 9 family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15799966
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21778237
uniprot
proteins
pubmed
23563313
uniprot
proteins
pubmed
23637203
uniprot
proteins
pubmed
25355947
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28892079
uniprot
proteins
pubmed
37172566
uniprot
proteins
pubmed
38459129
uniprot
proteins
pubmed
38504028
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21778237}. Cytoplasmic vesicle {ECO:0000269|PubMed:21778237}.
uniprot
proteins