TYW3
entrez
127253
canonical
uniprot
Q6IPR3
canonical
ensembl
ENSG00000162623
resolver
ensp
ENSP00000359904
resolver
ensp
ENSP00000407025
resolver
ensp
ENSP00000575183
resolver
genesymbol
TYW3
resolver
genesymbol_syn
C1orf171
resolver
hgnc
HGNC:24757
resolver
uniprot
B4DSP9
resolver
uniprot
E9PGR7
resolver
uniprot
Q5HYJ0
resolver
uniprot
Q8N7L1
resolver
uniprot
Q96GE7
resolver
uniprot_entry
Q96GE7_HUMAN
resolver
uniprot_entry
TYW3_HUMAN
resolver
uniprot_sec
B4DSP9
resolver
uniprot_sec
E9PGR7
resolver
uniprot_sec
Q5HYJ0
resolver
uniprot_sec
Q8N7L1
resolver
amino_acid_sequence
MDRSAEFRKWKAQCLSKADLSRKGSVDEDVVELVQFLNMRDQFFTTSSCAGRILLLDRGINGFEVQKQNCCWLLVTHKLCVKDDVIVALKKANGDATLKFEPFVLHVQCRQLQDAQILHSMAIDSGFRNSGITVGKRGKTMLAVRSTHGLEVPLSHKGKLMVTEEYIDFLLNVANQKMEENKKRIERFYNCLQHALERETMTNLHPKIKEKNNSSYIHKKKRNPEKTRAQCITKESDEELENDDDDDLGINVTIFPEDY
uniprot
proteins
ec_number
2.1.1.282
uniprot
proteins
function
FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame. Catalyzes the methylation of 4-demethylwyosine, generating intermediates required for the formation of mature wybutosine. {ECO:0000250|UniProtKB:P53177}.
uniprot
proteins
mass_dalton
29794
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
uniprot
proteins
protein_family
TYW3 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
259
uniprot
proteins