Myo3b
entrez
329421
canonical
uniprot
Q1EG27
canonical
ensembl
ENSMUSG00000042064
resolver
ensp
ENSMUSP00000055362
resolver
ensp
ENSMUSP00000107862
resolver
enst
ENSMUST00000060208
resolver
genesymbol
Myo3b
resolver
uniprot
A2AR19
resolver
uniprot
F8VQ79
resolver
uniprot
Q1EG26
resolver
uniprot_entry
F8VQ79_MOUSE
resolver
uniprot_entry
MYO3B_MOUSE
resolver
uniprot_sec
A2AR19
resolver
uniprot_sec
Q1EG26
resolver
amino_acid_sequence
MMLGLESLPDPMETWEIIETIGKGTYGKVYKVANKRDGSLAAVKVLDPVSDMDEEIEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRCGKRLDEAVISYILYGALLGLQHLHCHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPTLLHPDSWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFIKGTQGKVLCLQKQLAKVLQDQKHRNPVAKTRHERMHTGRPHRVEDAGKCCLEDDLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPHIFASADNAYQCLVTFSKDQCIVISGESGSGKTESAHLIVQHLTFLGKADNQTLRQKILQVNSLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEKNFHIFYYIYAGLYHQKKLAEFRLPEEKPPRYIAGETERVMQDITSKESYRTQFEAIQHCFKIIGFADKEVHSVYRILAGILNIGSIEFAAISSQHQTDKSEVPNPEALENAACVLCISSEELQEALTSHCVVTRGETIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNICSAEDRMNVGILDIFGFEDFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYKNEGVDAVLVQYEDNRPLLDMFLQKPLGLLALLDEESRFPQGTDQTLVDKFEDNLRCKFFWRPKGVELCFGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRAKITASSRSLPPHFSAGRAKVDTLEVIRHPEETTNMKRQTMASYFRYSLMDLLSKMVVGQPHFIRCIKPNDDRKALQFSQDRVLAQLRSTGILETVSIRRQGYSHRIFFEEFVKRYYYLAFRAHQTPPANKESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVMGRVVMLQAYTKGWLGARRYKRAKEKREKGAITIQSAWRGYDARRKLKQRSRRRSESEAHIHTVLQTTPDQKYCPDSGGESNRGHEETSRNCPAEADTDGHPQAQSPPTGCDVTSGHADTAAGYTVAELSVAGTDVSPSLVYHTASAHQRLSPCEDSLKPGSEEGLSQKQRAPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSQRKPRKLGQIKVLDGEDQYYKCLSPGACAPEETHSVHPFFFSSSPREDPFAQH
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Probable actin-based motor with a protein kinase activity (By similarity). Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern (PubMed:26754646). Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments (PubMed:22264607). {ECO:0000250|UniProtKB:Q8WXR4, ECO:0000269|PubMed:22264607, ECO:0000269|PubMed:26754646}.
uniprot
proteins
mass_dalton
148099
uniprot
proteins
protein_family
Myosin family; Protein kinase superfamily
uniprot
proteins
protein_family
STE Ser/Thr protein kinase family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22264607
uniprot
proteins
pubmed
26754646
uniprot
proteins
pubmed
26785147
uniprot
proteins
pubmed
26926603
uniprot
proteins
sequence_length
1305
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, stereocilium {ECO:0000269|PubMed:26754646}.
uniprot
proteins