Sfxn5
entrez
94282
canonical
uniprot
Q925N0
canonical
ensembl
ENSMUSG00000033720
resolver
ensp
ENSMUSP00000041872
resolver
ensp
ENSMUSP00000195140
resolver
ensp
ENSMUSP00000195141
resolver
enst
ENSMUST00000045846
resolver
genesymbol
Sfxn5
resolver
uniprot
Q8BGG3
resolver
uniprot_entry
SFXN5_MOUSE
resolver
uniprot_sec
Q8BGG3
resolver
amino_acid_sequence
MADTATTASAASAAASAPNASTDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIARATSSRTVVYNKGL
uniprot
proteins
function
FUNCTION: Mitochondrial amino-acid transporter (By similarity). Transports citrate (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). In brown adipose tissue, plays a role in the regulation of UCP1-dependent thermogenesis probably by supporting mitochondrial glycerol-3-phosphate utilization (PubMed:36334589). {ECO:0000250|UniProtKB:Q8CFD0, ECO:0000250|UniProtKB:Q8TD22, ECO:0000250|UniProtKB:Q9H9B4, ECO:0000269|PubMed:36334589}.
uniprot
proteins
mass_dalton
37329
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
11274051
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
36334589
uniprot
proteins
sequence_length
342
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:36334589}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 105..125; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 256..276; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 289..309; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins