Prop1
entrez
19127
canonical
uniprot
P97458
canonical
ensembl
ENSMUSG00000044542
resolver
ensp
ENSMUSP00000057231
resolver
enst
ENSMUST00000051159
resolver
genesymbol
Prop1
resolver
genesymbol_syn
Prop-1
resolver
uniprot
Q5NCG9
resolver
uniprot_entry
PROP1_MOUSE
resolver
uniprot_sec
Q5NCG9
resolver
amino_acid_sequence
MEAQRRSHQEKQTKGHACGRSLPEPRVASGTLISTVDRSSEAYRRLSGTELGRPKLCPQRGRPHSRRRHRTTFNPAQLEQLESAFGRNQYPDIWAREGLAQDTGLSEARIQVWFQNRRAKQRKQERSLLQPIAHLSTATFSGFLPESSAYPYTYGTPPPPAPCFPHPYSHSLPSQPSTAASLALPPQPEDWYPTLHPAPTGHLPCPPPPPMFPLSLETPKSWN
uniprot
proteins
function
FUNCTION: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
uniprot
proteins
mass_dalton
25025
uniprot
proteins
mutagenesis
MUTAGEN 83; /note="S->P: Shows very weak DNA binding to a Prop1 response element in gel shift assays; transcriptional activation of a luciferase reporter gene is reduced to 43% compared with that of wild-type Prop1 in transiently transfected human embryonic kidney cells."; /evidence="ECO:0000269|PubMed:10946881"; MUTAGEN 85; /note="F->S: Shows no significant DNA binding to a Prop1 response element in gel shift assays; transcriptional activation of a luciferase reporter gene is reduced to approximately 34% compared with that of wild-type Prop1 in transiently transfected human embryonic kidney cells."; /evidence="ECO:0000269|PubMed:10946881
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
10946881
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
8934515
uniprot
proteins
sequence_length
223
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
uniprot
proteins