PSMB11
entrez
122706
canonical
uniprot
A5LHX3
canonical
ensembl
ENSG00000222028
resolver
ensp
ENSP00000386212
resolver
enst
ENST00000408907
resolver
genesymbol
PSMB11
resolver
hgnc
HGNC:31963
resolver
uniprot
B3KVC3
resolver
uniprot_entry
B3KVC3_HUMAN
resolver
uniprot_entry
PSB11_HUMAN
resolver
amino_acid_sequence
MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV
uniprot
proteins
ec_number
3.4.25.1
uniprot
proteins
function
FUNCTION: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome (By similarity). Plays a pivotal role in development of CD8-positive T cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
32530
uniprot
proteins
protein_family
Peptidase T1B family
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
17540904
uniprot
proteins
sequence_length
300
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
uniprot
proteins