Mboat4
entrez
306515
canonical
uniprot
B1Q005
canonical
ensembl
ENSRNOG00000030102
resolver
ensp
ENSRNOP00000046106
resolver
enst
ENSRNOT00000042003
resolver
genesymbol
Mboat4
resolver
genesymbol_syn
Goat
resolver
uniprot_entry
MBOA4_RAT
resolver
amino_acid_sequence
MDWLQFFFLHPVSLYQGAAFPFALLFNYLCITESFPTRARYLFLLAGGGVLALAAMGPYALLIFIPALCAVAMISSLSPQEVHGLTFFFQMGWQTLCHLGLHYKEYYLCEPPPVRFYITLSSLMLLTQRVTSLSLDISEGKVEAAWRGTRSRSSLCEHLWDALPYISYLLFFPALLGGSLCSFQRFQACVQRPRSLYPSISFWALTWRGLQILGLECLKVALRRVVSAGAGLDDCQRLECIYIMWSTAGLFKLTYYSHWILDDSLLHAAGFGSEAGQRPGEERYVPDVDIWTLETTHRISLFARQWNRSTAQWLKRLVFQRSRRWPVLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHTFANGCIRSWPLRLLYRSLTWAHTQIIIAYVMLAVEGRSFSSLCRLCCSYNSIFPVTYCLLLFLLARRKHKCN
uniprot
proteins
ec_number
2.3.1.-
uniprot
proteins
function
FUNCTION: Catalyzes ghrelin acylation at 'Ser-3' using preferentially octanoyl-CoA, hexanoyl-CoA and decanoyl-CoA as acyl-CoA donors leading to ghrelin activity (By similarity) (PubMed:18443287). In vitro uses also acyl-CoA donors of different lengths from short-chain (C2) to long-chain fatty acids (C16) knowing that acyl-CoA donors from butanoyl-CoA (C4) to dodecanoyl-CoA (C12) are more efficient compared to longer acyl-CoA donors, such as myristoyl-CoA (C14) and palmitoyl-CoA (C16) that are not efficient (By similarity). {ECO:0000250|UniProtKB:Q96T53, ECO:0000269|PubMed:18443287}.
uniprot
proteins
mass_dalton
50008
uniprot
proteins
post_translational_modification
PTM: Not glycosylated. {ECO:0000250|UniProtKB:P0C7A3}.
uniprot
proteins
protein_family
Membrane-bound acyltransferase family
uniprot
proteins
pubmed
18443287
uniprot
proteins
sequence_length
435
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P0C7A3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P0C7A3}.
uniprot
proteins
transmembrane_region
TRANSMEM 6..26; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3, ECO:0000255"; TRANSMEM 41..56; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3, ECO:0000255"; TRANSMEM 60..76; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3"; TRANSMEM 83..101; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3"; TRANSMEM 121..136; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3"; TRANSMEM 207..227; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3"; TRANSMEM 241..261; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3, ECO:0000255"; TRANSMEM 325..338; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3"; TRANSMEM 341..357; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P0C7A3"; TRANSMEM 377..397; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 408..428; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins