Msra
entrez
29447
canonical
uniprot
Q923M1
canonical
ensembl
ENSRNOG00000012440
resolver
ensembl
ENSRNOG00055006610
resolver
ensembl
ENSRNOG00060021859
resolver
ensembl
ENSRNOG00065029301
resolver
ensp
ENSRNOP00000067242
resolver
ensp
ENSRNOP00000096051
resolver
enst
ENSRNOT00000095387
resolver
genesymbol
Msra
resolver
uniprot
A0A8I6AN14
resolver
uniprot
A9LAT3
resolver
uniprot
A9LAT4
resolver
uniprot_entry
A0A8I6AN14_RAT
resolver
uniprot_entry
MSRA_RAT
resolver
uniprot_sec
A9LAT3
resolver
uniprot_sec
A9LAT4
resolver
amino_acid_sequence
MLSASRRTLQLLSSSIPVRMMGDSSSKVISAEEALPGRTESIPVAAKHHVSGNRTVEPFPEGTQMAVFGMGCFWGAERKFWLLKGVYSTQVGFAGGYTRNPTYKEVCSEKTGHAEVVRVVYRPEHVSFEELLKVFWENHDPTQGMRQGNDCGTQYRSAVYPTSAVQMEAALKSKEEYQKVLSKHGFGPITTDIREGQVFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPTAIKK
uniprot
proteins
ec_number
1.8.4.11
uniprot
proteins
function
FUNCTION: Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation (PubMed:12693988). Plays a crucial role in repairing oxidized methionine residues in key lens proteins, such as alpha-crystallin (CRYAA/CRYAB) and cytochrome c (CYCS), thereby restoring their function and maintaining lens transparency. {ECO:0000250|UniProtKB:Q9D6Y7, ECO:0000269|PubMed:12693988}.; FUNCTION: [Isoform 1]: Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. {ECO:0000269|PubMed:11311146, ECO:0000269|PubMed:17907003}.; FUNCTION: [Isoform 2]: Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. {ECO:0000269|PubMed:17907003}.
uniprot
proteins
mass_dalton
25851
uniprot
proteins
protein_family
MsrA Met sulfoxide reductase family
uniprot
proteins
pubmed
11311146
uniprot
proteins
pubmed
12693988
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17907003
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:12693988}. Cytoplasm {ECO:0000269|PubMed:12693988}.; SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:17907003}. Cytoplasm {ECO:0000269|PubMed:17907003}.; SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion {ECO:0000269|PubMed:17907003}.
uniprot
proteins