B3GNT2
entrez
10678
canonical
uniprot
Q9NY97
canonical
ensembl
ENSG00000170340
resolver
ensp
ENSP00000305595
resolver
ensp
ENSP00000384692
resolver
genesymbol
B3GNT2
resolver
genesymbol_syn
B3GALT7
resolver
genesymbol_syn
B3GNT1
resolver
hgnc
HGNC:15629
resolver
uniprot
Q54AC1
resolver
uniprot
Q9NQQ9
resolver
uniprot
Q9NQR0
resolver
uniprot
Q9NUT9
resolver
uniprot_entry
B3GN2_HUMAN
resolver
uniprot_sec
Q54AC1
resolver
uniprot_sec
Q9NQQ9
resolver
uniprot_sec
Q9NQR0
resolver
uniprot_sec
Q9NUT9
resolver
amino_acid_sequence
MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLYPPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC
uniprot
proteins
ec_number
2.4.1.149
uniprot
proteins
function
FUNCTION: Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase. {ECO:0000269|PubMed:11042166, ECO:0000269|PubMed:18826941, ECO:0000269|PubMed:25279697, ECO:0000269|PubMed:9892646}.
uniprot
proteins
mass_dalton
46022
uniprot
proteins
mutagenesis
MUTAGEN 245; /note="D->A: Loss of enzymatic activity, no loss of B3GNT8-binding."; /evidence="ECO:0000269|PubMed:18826941
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000269|PubMed:18826941, ECO:0000269|PubMed:25279697}.
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
10580128
uniprot
proteins
pubmed
11042166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14759258
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
18826941
uniprot
proteins
pubmed
25279697
uniprot
proteins
pubmed
9892646
uniprot
proteins
sequence_length
397
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins