Taar7d
entrez
435206
canonical
uniprot
Q5QD10
canonical
ensembl
ENSMUSG00000095569
resolver
ensp
ENSMUSP00000090327
resolver
enst
ENSMUST00000092657
resolver
genesymbol
Taar7d
resolver
uniprot_entry
TAA7D_MOUSE
resolver
amino_acid_sequence
MATGDDSFPWDQDSILSRDLFSATSTELCYENLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGVMVMPFSMVRSVEGCWYFGESYCKFHSCFEGSFCYSSLFHLCFISVDRYIAVSDPLTYPTRFTASVSGKCITFSWLLSIIYSFSLLYTGANDAGLEDLVSALTCVGGCQIAVNQTWVFINFLLFLIPTLVMITVYSKIFLIAKQQAQNIEKMSKQTARASESYKDRVTKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFITPTYVYEILVWIVYYNSAMNPLIYAFFYSWFRKAIKLIVSGKILRENSSTTNLFPE
uniprot
proteins
function
FUNCTION: Olfactory receptor specific for trace amines, such as beta-phenylethylamine (beta-PEA) (PubMed:37225986). Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors (PubMed:37225986). Ligand-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS) (PubMed:37225986). {ECO:0000269|PubMed:37225986}.
uniprot
proteins
mass_dalton
40305
uniprot
proteins
mutagenesis
MUTAGEN 124..128; /note="SCFEG->TCFET: Promotes trace-amine receptor activity toward polyamines, such as spermidine."; /evidence="ECO:0000269|PubMed:37225986"; MUTAGEN 132; /note="Y->L,T: Decreased trace-amine receptor activity in response to beta-phenylethylamine-binding."; /evidence="ECO:0000269|PubMed:37225986"; MUTAGEN 289; /note="Y->C: Decreased trace-amine receptor activity in response to beta-phenylethylamine-binding."; /evidence="ECO:0000269|PubMed:37225986"; MUTAGEN 308; /note="Y->L: Decreased trace-amine receptor activity in response to beta-phenylethylamine-binding."; /evidence="ECO:0000269|PubMed:37225986"; MUTAGEN 312; /note="V->T,C: Decreased trace-amine receptor activity in response to beta-phenylethylamine-binding."; /evidence="ECO:0000269|PubMed:37225986
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15718104
uniprot
proteins
pubmed
16878137
uniprot
proteins
pubmed
23624375
uniprot
proteins
pubmed
37225986
uniprot
proteins
sequence_length
358
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q923X5}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 48..68; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 84..104; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 122..143; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 213..233; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 275..295; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 310..333; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins