Asprv1
entrez
67855
canonical
uniprot
Q09PK2
canonical
ensembl
ENSMUSG00000033508
resolver
ensp
ENSMUSP00000046121
resolver
enst
ENSMUST00000043400
resolver
genesymbol
Asprv1
resolver
genesymbol_syn
Sasp
resolver
genesymbol_syn
Taps
resolver
uniprot
A0A8D3UE05
resolver
uniprot
Q0VEV3
resolver
uniprot
Q32P05
resolver
uniprot
Q6PEP7
resolver
uniprot
Q9D135
resolver
uniprot_entry
A0A8D3UE05_MOUSE
resolver
uniprot_entry
APRV1_MOUSE
resolver
uniprot_sec
Q0VEV3
resolver
uniprot_sec
Q32P05
resolver
uniprot_sec
Q6PEP7
resolver
uniprot_sec
Q9D135
resolver
amino_acid_sequence
MRNPGGPGWASKRPLQKKQNTACLCAQQPARHFVPAPFNSSRQGKNTAQPTEPSLSSVIAPTLFCAFLYLACVTAELPEVSRRMATSGVRSKEGRREHAFVPEPFTGTNLAPSLWLHRFEVIDDLNHWDHATKLRFLKESLKGDALDVYNGLSSQAQGDFSFVKQALLRAFGAPGEAFSEPEEILFANSMGKGYYLKGKVGHVPVRFLVDSGAQVSVVHPALWEEVTDGDLDTLRPFNNVVKVANGAEMKILGVWDTEISLGKTKLKAEFLVANASAEEAIIGTDVLQDHNAVLDFEHRTCTLKGKKFRLLPVGSSLEDEFDLELIEEEEGSSAPEGSH
uniprot
proteins
ec_number
3.4.23.-
uniprot
proteins
function
FUNCTION: Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization. {ECO:0000250|UniProtKB:Q53RT3}.
uniprot
proteins
mass_dalton
37174
uniprot
proteins
mutagenesis
MUTAGEN 210; /note="D->A: Abolishes production of active form of enzyme."; /evidence="ECO:0000269|PubMed:16837463
uniprot
proteins
post_translational_modification
PTM: Undergoes autocleavage which is necessary for activation of the protein. {ECO:0000269|PubMed:16837463}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16565508
uniprot
proteins
pubmed
16837463
uniprot
proteins
sequence_length
339
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins