Pdlim5
entrez
56376
canonical
uniprot
Q8CI51
canonical
ensembl
ENSMUSG00000028273
resolver
ensp
ENSMUSP00000029941
resolver
ensp
ENSMUSP00000087595
resolver
ensp
ENSMUSP00000128752
resolver
ensp
ENSMUSP00000132647
resolver
ensp
ENSMUSP00000142460
resolver
ensp
ENSMUSP00000142737
resolver
ensp
ENSMUSP00000142899
resolver
ensp
ENSMUSP00000143098
resolver
ensp
ENSMUSP00000143343
resolver
ensp
ENSMUSP00000240589
resolver
ensp
ENSMUSP00000240590
resolver
ensp
ENSMUSP00000240591
resolver
ensp
ENSMUSP00000240592
resolver
ensp
ENSMUSP00000240598
resolver
ensp
ENSMUSP00000240600
resolver
ensp
ENSMUSP00000240608
resolver
ensp
ENSMUSP00000240612
resolver
ensp
ENSMUSP00000240637
resolver
ensp
ENSMUSP00000356023
resolver
enst
ENSMUST00000090134
resolver
enst
ENSMUST00000168967
resolver
enst
ENSMUST00000170361
resolver
enst
ENSMUST00000195975
resolver
enst
ENSMUST00000196220
resolver
enst
ENSMUST00000198381
resolver
enst
ENSMUST00000200043
resolver
genesymbol
Pdlim5
resolver
genesymbol_syn
Enh
resolver
uniprot
A0A0G2JDQ5
resolver
uniprot
A0A0G2JEE3
resolver
uniprot
A0A0G2JET5
resolver
uniprot
A0A0G2JFX5
resolver
uniprot
A0A140T8T8
resolver
uniprot
D9J2Z9
resolver
uniprot
D9J300
resolver
uniprot
D9J301
resolver
uniprot
D9J302
resolver
uniprot
D9J303
resolver
uniprot
E9Q8P5
resolver
uniprot
F8WGG4
resolver
uniprot
Q3UGD0
resolver
uniprot
Q9CRA2
resolver
uniprot
Q9QYN0
resolver
uniprot
Q9QYN1
resolver
uniprot
Q9QYN2
resolver
uniprot_entry
A0A0G2JDQ5_MOUSE
resolver
uniprot_entry
A0A0G2JEE3_MOUSE
resolver
uniprot_entry
A0A0G2JET5_MOUSE
resolver
uniprot_entry
A0A0G2JFX5_MOUSE
resolver
uniprot_entry
A0A140T8T8_MOUSE
resolver
uniprot_entry
D9J2Z9_MOUSE
resolver
uniprot_entry
D9J300_MOUSE
resolver
uniprot_entry
D9J301_MOUSE
resolver
uniprot_entry
D9J302_MOUSE
resolver
uniprot_entry
D9J303_MOUSE
resolver
uniprot_entry
E9Q8P5_MOUSE
resolver
uniprot_entry
F8WGG4_MOUSE
resolver
uniprot_entry
PDLI5_MOUSE
resolver
uniprot_entry
Q9CRA2_MOUSE
resolver
uniprot_sec
Q3UGD0
resolver
uniprot_sec
Q9QYN0
resolver
uniprot_sec
Q9QYN1
resolver
uniprot_sec
Q9QYN2
resolver
amino_acid_sequence
MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKASQAHVRIGDVVLSIDGISAQGMTHLEAQNKIKACTGSLNMTLQRASAAAKSEPVSVQKGEPKEVVKPVPITSPAVSKVTSTTNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHAATSSHASPTPVAAATPLHLSASGLHVSANLSADQCSSPPNTGKPAVNVPRQPTVTSVCSESAQELAEGQRRGSQGDIKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLTESENDNTKKANSTQEPSQQPASSGASPLSASEGPESPGSSRPSVAGLRSAAAFKPVGSTSVKSPSWQRPNQAAPSTGRISNNARSSGTGASVGPPQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVINALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF
uniprot
proteins
function
FUNCTION: May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May be required to restrain postsynaptic growth of excitatory synapses. Isoform 1, but not isoform 2, expression favors spine thinning and elongation. {ECO:0000250|UniProtKB:Q62920}.
uniprot
proteins
mass_dalton
63299
uniprot
proteins
pubmed
10833443
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
591
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic density {ECO:0000250|UniProtKB:Q62920}. Presynapse {ECO:0000250|UniProtKB:Q62920}. Postsynapse {ECO:0000250|UniProtKB:Q62920}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q62920}. Note=Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons. {ECO:0000250|UniProtKB:Q62920}.
uniprot
proteins