JOSD2
entrez
126119
canonical
uniprot
Q8TAC2
canonical
ensembl
ENSG00000161677
resolver
ensp
ENSP00000468860
resolver
ensp
ENSP00000468956
resolver
ensp
ENSP00000470628
resolver
ensp
ENSP00000472116
resolver
ensp
ENSP00000554090
resolver
genesymbol
JOSD2
resolver
hgnc
HGNC:28853
resolver
uniprot
M0QX25
resolver
uniprot
Q7Z7N5
resolver
uniprot_entry
JOS2_HUMAN
resolver
uniprot_entry
Q7Z7N5_HUMAN
resolver
uniprot_sec
M0QX25
resolver
amino_acid_sequence
MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEEKGSWLRTD
uniprot
proteins
ec_number
3.4.19.12
uniprot
proteins
function
FUNCTION: Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme. {ECO:0000269|PubMed:17696782, ECO:0000269|PubMed:21118805, ECO:0000269|PubMed:23625928}.
uniprot
proteins
mass_dalton
20756
uniprot
proteins
mutagenesis
MUTAGEN 24; /note="C->A: Loss of deubiquitination activity, no change in subcellular location."; /evidence="ECO:0000269|PubMed:23625928
uniprot
proteins
pubmed
12486728
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17696782
uniprot
proteins
pubmed
21118805
uniprot
proteins
pubmed
23625928
uniprot
proteins
sequence_length
188
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:23625928}.
uniprot
proteins