Ptov1
entrez
84113
canonical
uniprot
Q91VU8
canonical
ensembl
ENSMUSG00000038502
resolver
ensp
ENSMUSP00000035281
resolver
ensp
ENSMUSP00000204602
resolver
enst
ENSMUST00000046575
resolver
genesymbol
Ptov1
resolver
uniprot
Q9CTC2
resolver
uniprot_entry
PTOV1_MOUSE
resolver
uniprot_sec
Q9CTC2
resolver
amino_acid_sequence
MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRSRSWPGGPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRRVIANQQQVLQRSLEQEQQQRGMGG
uniprot
proteins
function
FUNCTION: May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. {ECO:0000250|UniProtKB:Q86YD1}.
uniprot
proteins
mass_dalton
46865
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the CRL2(KLHDC2) complex, which recognizes the diglycine (Gly-Gly) at the C-terminus, leading to its degradation. Ubiquitinated by the CRL2(APPBP2) complex, which recognizes the Arg-Xaa-Xaa-Gly sequence at the C-terminus, leading to its degradation. {ECO:0000250|UniProtKB:Q86YD1}.
uniprot
proteins
protein_family
Mediator complex subunit 25 family
uniprot
proteins
protein_family
PTOV1 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
416
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86YD1}. Nucleus {ECO:0000250|UniProtKB:Q86YD1}. Cell membrane {ECO:0000250|UniProtKB:Q86YD1}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q86YD1}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts. {ECO:0000250|UniProtKB:Q86YD1}.
uniprot
proteins