NPVF
entrez
64111
canonical
uniprot
Q9HCQ7
canonical
ensembl
ENSG00000105954
resolver
ensp
ENSP00000222674
resolver
genesymbol
NPVF
resolver
genesymbol_syn
C7orf9
resolver
genesymbol_syn
RFRP
resolver
hgnc
HGNC:13782
resolver
uniprot
A4D164
resolver
uniprot
Q7LE27
resolver
uniprot
Q96PI9
resolver
uniprot_entry
NPVF_HUMAN
resolver
uniprot_sec
A4D164
resolver
uniprot_sec
Q7LE27
resolver
uniprot_sec
Q96PI9
resolver
amino_acid_sequence
MEIISSKLFILLTLATSSLLTSNIFCADELVMSNLHSKENYDKYSEPRGYPKGERSLNFEELKDWGPKNVIKMSTPAVNKMPHSFANLPLRFGRNVQEERSAGATANLPLRSGRNMEVSLVRRVPNLPQRFGRTTTAKSVCRMLSDLCQGSMHSPCANDLFYSMTCQHQEIQNPDQKQSRRLLFKKIDDAELKQEK
uniprot
proteins
function
FUNCTION: [Neuropeptide RFRP-1]: Efficiently inhibits forskolin-induced production of cAMP. Acts as a potent negative regulator of gonadotropin synthesis and secretion (PubMed:11025660, PubMed:20027225). Induces secretion of prolactin (By similarity). {ECO:0000250|UniProtKB:Q9ESQ9, ECO:0000269|PubMed:11025660, ECO:0000269|PubMed:20027225}.; FUNCTION: [Neuropeptide NPVF]: Efficiently inhibits forskolin-induced production of cAMP. Blocks morphine-induced analgesia. {ECO:0000269|PubMed:11025660, ECO:0000269|PubMed:20027225}.; FUNCTION: [Neuropeptide RFRP-2]: Shows no inhibitory activity of forskolin-induced production of cAMP. {ECO:0000269|PubMed:11025660}.
uniprot
proteins
mass_dalton
22327
uniprot
proteins
protein_family
FARP (FMRFamide related peptide) family
uniprot
proteins
pubmed
11025660
uniprot
proteins
pubmed
11481330
uniprot
proteins
pubmed
11951088
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
20027225
uniprot
proteins
sequence_length
196
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:11025660}.
uniprot
proteins