F13a1
entrez
74145
canonical
uniprot
Q8BH61
canonical
ensembl
ENSMUSG00000039109
resolver
ensp
ENSMUSP00000048667
resolver
ensp
ENSMUSP00000128316
resolver
enst
ENSMUST00000037491
resolver
enst
ENSMUST00000164727
resolver
genesymbol
F13a1
resolver
genesymbol_syn
F13a
resolver
uniprot
Q3TNF9
resolver
uniprot
Q3V3W7
resolver
uniprot
Q8BIP2
resolver
uniprot_entry
F13A_MOUSE
resolver
uniprot_entry
Q3V3W7_MOUSE
resolver
uniprot_sec
Q3TNF9
resolver
uniprot_sec
Q8BIP2
resolver
amino_acid_sequence
MSDTPASTFGGRRAVPPNNSNAAEVDLPTEELQGLVPRGVNLKDYLNVTAVHLFKERWDSNKIDHHTDKYDNNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVKELQSGKWGAKVIMNEDRSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTRRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDIGVIFYGDFKDIKSRSWSYGQFEDGILDTCLYVMDKAEMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNVYAYGIPPSAWTGSVDILLEYRSSETPVRYGQCWVFAGVFNTFLRCLGIPARVITNYFSAHDNDANLQMDIFLEEDGNVSSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAVKHGHVCFQFDAPFVFAEVNSDLVYITAKQDGTHVVEAVDATHIGKLIVTKQIGGDGMQDITDTYKFQEGQEEERLALETALMYGAKKTLNTEGVVKSRSDVTMNFDVENAVLGKDFKVTITFQNNSSNLYTILAYLSGNITFYTGVSKKEFKKESFEETLDPFSSKKKEVLVRAGEYMSHLLEQGFLHFFVTARINESRDVLAKQKSIILTIPKITIKVRGAAMVGSDMVVTVEFTNPLKETLQNVWIHLDGPGVMRPKRKVFREIRPNTTVQWEEVCRPWVSGHRKLIASMTSDSLRHVYGELDLQIQRRPTM
uniprot
proteins
ec_number
2.3.2.13
uniprot
proteins
function
FUNCTION: Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. {ECO:0000250|UniProtKB:P00488}.
uniprot
proteins
mass_dalton
83207
uniprot
proteins
post_translational_modification
PTM: The activation peptide is released by thrombin. {ECO:0000250}.
uniprot
proteins
protein_family
Transglutaminase family
uniprot
proteins
protein_family
Transglutaminase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
732
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P00488}. Secreted {ECO:0000250|UniProtKB:P00488}. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma. {ECO:0000250|UniProtKB:P00488}.
uniprot
proteins