Lrrfip1
entrez
16978
canonical
uniprot
Q3UZ39
canonical
ensembl
ENSMUSG00000026305
resolver
ensp
ENSMUSP00000065850
resolver
ensp
ENSMUSP00000095254
resolver
ensp
ENSMUSP00000095255
resolver
ensp
ENSMUSP00000139497
resolver
ensp
ENSMUSP00000139811
resolver
ensp
ENSMUSP00000284324
resolver
ensp
ENSMUSP00000284326
resolver
ensp
ENSMUSP00000284327
resolver
ensp
ENSMUSP00000284330
resolver
ensp
ENSMUSP00000284343
resolver
enst
ENSMUST00000068116
resolver
enst
ENSMUST00000189617
resolver
genesymbol
Lrrfip1
resolver
genesymbol_syn
Flap
resolver
uniprot
A0A087WPK3
resolver
uniprot
A6H5U5
resolver
uniprot
G5E8E1
resolver
uniprot
O70323
resolver
uniprot
Q3TS94
resolver
uniprot
Q8BLV4
resolver
uniprot_entry
A0A087WPK3_MOUSE
resolver
uniprot_entry
A6H5U5_MOUSE
resolver
uniprot_entry
G5E8E1_MOUSE
resolver
uniprot_entry
LRRF1_MOUSE
resolver
uniprot_entry
Q8BLV4_MOUSE
resolver
uniprot_sec
O70323
resolver
uniprot_sec
Q3TS94
resolver
amino_acid_sequence
MTSPEGAQNKEIDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKEVEERPDKDFAEKGSRNMPSLSAATLASLGGTSSRRGSGDTSISMDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESQRQYEEKNKEFEREKHAHSILQFQFAEVKEALRQREEMLEKHGIILNSEIATNGETSDTVNDVGYQAPTKITKEELNALKSAGEGTLGKAKEVEVKKEIVEKVGQRETLQNSEQEQPKPNTGKDCVDRGVSHPGEKAENQRPAEDSALSPGPLAGAKCEQQVQSQDQENTSDLKNSEQIESHKVTNKSDSRASNSPEQSSCLEGLDSEVPGPTEDLKTDLGKGSFEPCPDYILGQTAEIDKVTCTDSRGTGGNQREDEVQAGDTTVEDQVGTVASGPAKQSKGTENHGESCLKDGLGQSSERELTQEVAEPEEAIVQIPQAGGENTITKADDAEGRDEKPIQAEAQASPGAPINQSGHQDTTGPGSTDAQRTPPHAKERKKQGKSEQQAEALDSPQKKTKNKKKKNKKKKAATPAETCRDANEELNCQDPDVGDMEEEERLQVTDKKQASGSPEQKIRAGSREPVEDPQSGSSGKQNKVEEDGPTEGPTDILDQNSPQCEDREISPVGEKGPQCDTSQIGSEEGHVTSQHGGQAVENHNLDNSDLSGQLEGFNSESGGQAREEVGNSKSKEDCTMS
uniprot
proteins
function
FUNCTION: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA (By similarity). Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
79249
uniprot
proteins
protein_family
LRRFIP family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9525888
uniprot
proteins
sequence_length
729
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}.
uniprot
proteins