Dcaf5
entrez
320808
canonical
uniprot
Q80T85
canonical
ensembl
ENSMUSG00000049106
resolver
ensp
ENSMUSP00000052755
resolver
enst
ENSMUST00000054145
resolver
genesymbol
Dcaf5
resolver
genesymbol_syn
Kiaa1824
resolver
genesymbol_syn
Wdr22
resolver
uniprot
Q3UV57
resolver
uniprot
Q80VT3
resolver
uniprot
Q80ZW6
resolver
uniprot
Q8BIP8
resolver
uniprot
Q8BVK5
resolver
uniprot
Q8K0Q6
resolver
uniprot_entry
DCAF5_MOUSE
resolver
uniprot_entry
Q3UV57_MOUSE
resolver
uniprot_sec
Q80VT3
resolver
uniprot_sec
Q80ZW6
resolver
uniprot_sec
Q8BIP8
resolver
uniprot_sec
Q8BVK5
resolver
uniprot_sec
Q8K0Q6
resolver
amino_acid_sequence
MKRRAGLGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWKIPADPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSPPPTVDESADNAFHLGPLRVTTTNAVASTPATPTCEDASSRQQRLSALRRYQDKRLLALSNESDSEENVCEAELDTDLFPRPRSPSPEDGSSSPSSSTSSEDEEELNQRRATTRQRNAMRRRQKTARDERPTGPAKSTNTYIGEDNYDYPQIKVDDLSPSPDSSPERSASTLDVQPSRAPPAANMESVERKIYKAYKWLRCSYISYSNNKDGETSLMAEEADEGRAGTSHKDNPTPSSSKEACLTATAQRDQDLPSEGCSSDACKEGTSAGNPNSGAGHEHSSHPWAEVPEGTSQDTNNSGPLEHSFETKKLNGKALSKALSSRAEEPPASPGPKASGSTLNSASGNCPRTQSDDSEERSLDTVCANHNNGRLHPRPLHPHNNGQSSGELETVACSSPGHLDTDHDSPSLTGTFLHKDCCGSEMACETPSAGMREDPPDPSGLDSSKVVHGQSGLKRHRIELEDTESENSSSEKKLKT
uniprot
proteins
function
FUNCTION: Is a substrate receptor for the CUL4-DDB1 E3 ubiquitin-protein ligase complex (CRL4), involved in the ubiquitination of a set of methylated non-histone proteins, including SOX2 (PubMed:30442713). The complex CRL4-DCAF5 is also involved in the ubiquitination of methylated DNMT1 and E2F1 (By similarity). {ECO:0000250|UniProtKB:Q96JK2, ECO:0000269|PubMed:30442713}.
uniprot
proteins
mass_dalton
103676
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30442713
uniprot
proteins
sequence_length
946
uniprot
proteins