Dlg2
entrez
23859
canonical
uniprot
Q91XM9
canonical
ensembl
ENSMUSG00000052572
resolver
ensp
ENSMUSP00000095910
resolver
ensp
ENSMUSP00000102811
resolver
ensp
ENSMUSP00000102814
resolver
ensp
ENSMUSP00000155862
resolver
ensp
ENSMUSP00000158695
resolver
ensp
ENSMUSP00000158731
resolver
enst
ENSMUST00000098308
resolver
enst
ENSMUST00000238467
resolver
genesymbol
Dlg2
resolver
genesymbol_syn
Dlgh2
resolver
uniprot
A0A2L2P590
resolver
uniprot
A0A2L2P595
resolver
uniprot
A0A571BEZ4
resolver
uniprot
D3YWU0
resolver
uniprot
F8VQM7
resolver
uniprot
Q8BXK7
resolver
uniprot
Q8BYG5
resolver
uniprot_entry
A0A2L2P590_MOUSE
resolver
uniprot_entry
A0A571BEZ4_MOUSE
resolver
uniprot_entry
D3YWU0_MOUSE
resolver
uniprot_entry
DLG2_MOUSE
resolver
uniprot_sec
A0A2L2P595
resolver
uniprot_sec
F8VQM7
resolver
uniprot_sec
Q8BXK7
resolver
uniprot_sec
Q8BYG5
resolver
amino_acid_sequence
MFFACYCALRTNVKKYRYQDEDGPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSDVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLGEDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSTPYPHYHLGLLPDSDMTSHSQHSTATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVTLDGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
uniprot
proteins
function
FUNCTION: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses. {ECO:0000269|PubMed:12890763}.
uniprot
proteins
mass_dalton
94880
uniprot
proteins
post_translational_modification
PTM: Palmitoylation of isoform 1 and isoform 2 is not required for targeting to postsynaptic density. {ECO:0000250}.
uniprot
proteins
pubmed
11997254
uniprot
proteins
pubmed
12890763
uniprot
proteins
pubmed
14724236
uniprot
proteins
pubmed
15304517
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
19243221
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20054121
uniprot
proteins
pubmed
20089912
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29703139
uniprot
proteins
sequence_length
852
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:11997254}; Lipid-anchor {ECO:0000250|UniProtKB:Q63622}. Postsynaptic density {ECO:0000250|UniProtKB:Q63622}. Synapse {ECO:0000250}. Membrane {ECO:0000250|UniProtKB:Q63622}. Cell projection, axon {ECO:0000250|UniProtKB:Q63622}. Perikaryon {ECO:0000250|UniProtKB:Q63622}. Note=Concentrated in soma and postsynaptic density of a subset of neurons. {ECO:0000250|UniProtKB:Q63622}.
uniprot
proteins