Crcp
entrez
114205
canonical
uniprot
Q8VHM6
canonical
ensembl
ENSRNOG00000071267
resolver
ensembl
ENSRNOG00055000389
resolver
ensembl
ENSRNOG00060011312
resolver
ensembl
ENSRNOG00065001084
resolver
ensp
ENSRNOP00000098382
resolver
ensp
ENSRNOP00000101135
resolver
ensp
ENSRNOP00055000551
resolver
ensp
ENSRNOP00060014969
resolver
ensp
ENSRNOP00065001010
resolver
enst
ENSRNOT00000120757
resolver
enst
ENSRNOT00000136822
resolver
enst
ENSRNOT00055000694
resolver
enst
ENSRNOT00060019149
resolver
enst
ENSRNOT00065001431
resolver
genesymbol
Crcp
resolver
uniprot
A0ABK0L8Q6
resolver
uniprot
Q9Z0W9
resolver
uniprot_entry
A0ABK0L8Q6_RAT
resolver
uniprot_entry
RPC9_RAT
resolver
uniprot_sec
Q9Z0W9
resolver
amino_acid_sequence
MEVKDANAALLSNYEVFQLLTDLKEQRKESGKNKHSAGQQNLNAITYETLKYISKTPCKNQSPAIVQEFLTAMKSHKLTKAEKLQLLNHRPMTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEDEQSKSTSNDAAMEEEEPA
uniprot
proteins
function
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity). Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With POLR3H/RPC8 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation (By similarity). Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway (By similarity). {ECO:0000250|UniProtKB:O75575, ECO:0000250|UniProtKB:Q9C0Z9}.; FUNCTION: Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues. {ECO:0000250|UniProtKB:O35427}.
uniprot
proteins
mass_dalton
16627
uniprot
proteins
protein_family
Eukaryotic RPC9 RNA polymerase subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
148
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O75575}. Cell membrane {ECO:0000250|UniProtKB:O35427}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35427}; Cytoplasmic side {ECO:0000250|UniProtKB:O35427}.
uniprot
proteins