Tnni3
entrez
29248
canonical
uniprot
P23693
canonical
ensembl
ENSRNOG00055015678
resolver
ensembl
ENSRNOG00060027044
resolver
ensembl
ENSRNOG00065032480
resolver
ensp
ENSRNOP00055021665
resolver
ensp
ENSRNOP00060039066
resolver
ensp
ENSRNOP00065046053
resolver
enst
ENSRNOT00055026732
resolver
enst
ENSRNOT00060046975
resolver
enst
ENSRNOT00065055923
resolver
genesymbol
Tnni3
resolver
genesymbol_syn
Ctni
resolver
genesymbol_syn
Tni
resolver
uniprot
Q4PP23
resolver
uniprot_entry
TNNI3_RAT
resolver
uniprot_sec
Q4PP23
resolver
amino_acid_sequence
MADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSKISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLSTRCQPLVLDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKKEDIEKENREVGDWRKNIDALSGMEGRKKKFEG
uniprot
proteins
function
FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
uniprot
proteins
mass_dalton
24160
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-32. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T). Phosphorylated at Ser-43 and Ser-45 by PRKCE; phosphorylation increases myocardium contractile dysfunction (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Troponin I family
uniprot
proteins
pubmed
15601779
uniprot
proteins
pubmed
1886137
uniprot
proteins
pubmed
1935696
uniprot
proteins
pubmed
1988058
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9065755
uniprot
proteins
sequence_length
211
uniprot
proteins