MTMR1
entrez
8776
canonical
uniprot
Q13613
canonical
ensembl
ENSG00000063601
resolver
ensp
ENSP00000359417
resolver
ensp
ENSP00000414178
resolver
ensp
ENSP00000436957
resolver
ensp
ENSP00000445281
resolver
ensp
ENSP00000584529
resolver
ensp
ENSP00000584530
resolver
ensp
ENSP00000702839
resolver
enst
ENST00000445323
resolver
enst
ENST00000490316
resolver
enst
ENST00000542156
resolver
genesymbol
MTMR1
resolver
hgnc
HGNC:7449
resolver
uniprot
A0A024RC07
resolver
uniprot
B7Z3D5
resolver
uniprot
E9PPP8
resolver
uniprot
F6SKK4
resolver
uniprot
F8WA39
resolver
uniprot
Q8NEC6
resolver
uniprot
Q9UBX6
resolver
uniprot
Q9UEM0
resolver
uniprot
Q9UQD5
resolver
uniprot_entry
B7Z3D5_HUMAN
resolver
uniprot_entry
E9PPP8_HUMAN
resolver
uniprot_entry
F6SKK4_HUMAN
resolver
uniprot_entry
F8WA39_HUMAN
resolver
uniprot_entry
MTMR1_HUMAN
resolver
uniprot_entry
Q8NEC6_HUMAN
resolver
uniprot_sec
A0A024RC07
resolver
uniprot_sec
Q9UBX6
resolver
uniprot_sec
Q9UEM0
resolver
uniprot_sec
Q9UQD5
resolver
amino_acid_sequence
MDRPAAAAAAGCEGGGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVATRAVSSSSERGSSPSHSATSVHTSV
uniprot
proteins
ec_number
3.1.3.-
uniprot
proteins
ec_number
3.1.3.95
uniprot
proteins
function
FUNCTION: Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate, generating phosphatidylinositol (PubMed:11733541, PubMed:27018598). Could also dephosphorylate phosphatidylinositol 3,5-bisphosphate to produce phosphatidylinositol 5-phosphate (PubMed:27018598). {ECO:0000269|PubMed:11733541, ECO:0000269|PubMed:27018598}.
uniprot
proteins
mass_dalton
74678
uniprot
proteins
mutagenesis
MUTAGEN 438; /note="C->S: Abolishes enzyme activity."; /evidence="ECO:0000269|PubMed:27018598"; MUTAGEN 443; /note="D->A: Abolishes enzyme activity."; /evidence="ECO:0000269|PubMed:27018598"; MUTAGEN 444; /note="R->A: Abolishes enzyme activity with phosphatidylinositol 3-phosphate. Reduces activity with phosphatidylinositol (3,5)-bisphosphate."; /evidence="ECO:0000269|PubMed:27018598"; MUTAGEN 484; /note="R->A: Abolishes enzyme activity."; /evidence="ECO:0000269|PubMed:27018598
uniprot
proteins
protein_family
Non-receptor class myotubularin subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
11733541
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
27018598
uniprot
proteins
pubmed
8640223
uniprot
proteins
pubmed
9736772
uniprot
proteins
pubmed
9828128
uniprot
proteins
sequence_length
665
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9Z2C4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9Z2C4}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Z2C4}. Cytoplasm {ECO:0000250|UniProtKB:Q9Z2C4}.
uniprot
proteins