Ccdc42
entrez
276920
canonical
uniprot
Q5SV66
canonical
ensembl
ENSMUSG00000045915
resolver
ensp
ENSMUSP00000114381
resolver
genesymbol
Ccdc42
resolver
uniprot
B9EHU2
resolver
uniprot
Q8BNY1
resolver
uniprot_entry
CCD42_MOUSE
resolver
uniprot_sec
B9EHU2
resolver
uniprot_sec
Q8BNY1
resolver
amino_acid_sequence
MSLGMMEEEDLAEYFRLQYGERLLQLLQKFPNVEEQSDSPSIQLLEKKKEAKIMQEAMEHKKEAFQRRMETLNLRWEELGIKEEQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRLRLRELAKAKQEMMALRLEHQKLSVKLQDYAIFNKYLEKVVENSEFEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQHNNELARLQMRFDRARSDVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKQLKESTQVSLEDTHKQLDMIQQFIQDLSDIWTEVKKKEQQQVRM
uniprot
proteins
function
FUNCTION: Essential for male fertility (PubMed:26945718). Required for sperm development (PubMed:26945718). {ECO:0000269|PubMed:26945718}.
uniprot
proteins
mass_dalton
37989
uniprot
proteins
protein_family
CFAP73 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
26945718
uniprot
proteins
pubmed
31475146
uniprot
proteins
pubmed
34124066
uniprot
proteins
pubmed
35587122
uniprot
proteins
pubmed
38038747
uniprot
proteins
sequence_length
316
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000269|PubMed:31475146}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:31475146}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:31475146}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:31475146}. Note=Weakly expressed in the cytoplasm of round spermatids. In elongating spermatids, localizes to the manchette microtubules and the perinuclear ring. In the sperm flagellum, strongly expressed in the principle piece and also located to the connecting piece and weakly to the midpiece. Localizes to the centrosome in somatic cells. {ECO:0000269|PubMed:31475146}.
uniprot
proteins