RAB11FIP4
entrez
84440
canonical
uniprot
Q86YS3
canonical
ensembl
ENSG00000131242
resolver
ensp
ENSP00000378227
resolver
ensp
ENSP00000482620
resolver
genesymbol
RAB11FIP4
resolver
genesymbol_syn
ARFO2
resolver
genesymbol_syn
KIAA1821
resolver
hgnc
HGNC:30267
resolver
uniprot
Q52LI1
resolver
uniprot
Q8N829
resolver
uniprot
Q8NDT7
resolver
uniprot
Q969D8
resolver
uniprot_entry
RFIP4_HUMAN
resolver
uniprot_sec
Q52LI1
resolver
uniprot_sec
Q8N829
resolver
uniprot_sec
Q8NDT7
resolver
uniprot_sec
Q969D8
resolver
amino_acid_sequence
MAGGAGWSGAPAALLRSVRRLREVFEVCGRDPDGFLRVERVAALGLRFGQGEEVEKLVKYLDPNDLGRINFKDFCRGVFAMKGCEELLKDVLSVESAGTLPCAPEIPDCVEQGSEVTGPTFADGELIPREPGFFPEDEEEAMTLAPPEGPQELYTDSPMESTQSLEGSVGSPAEKDGGLGGLFLPEDKSLVHTPSMTTSDLSTHSTTSLISNEEQFEDYGEGDDVDCAPSSPCPDDETRTNVYSDLGSSVSSSAGQTPRKMRHVYNSELLDVYCSQCCKKINLLNDLEARLKNLKANSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDSLTNGDLKSKLKQENTQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEIDTASRDELMEALKEQEEINFRLRQYMDKIILAILDHNPSILEIKH
uniprot
proteins
function
FUNCTION: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abscission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6. {ECO:0000269|PubMed:12470645}.
uniprot
proteins
mass_dalton
71928
uniprot
proteins
mutagenesis
MUTAGEN 627; /note="D->A: Abolishes Rab11-binding."; /evidence="ECO:0000269|PubMed:16148947
uniprot
proteins
pubmed
11347906
uniprot
proteins
pubmed
11944901
uniprot
proteins
pubmed
12470645
uniprot
proteins
pubmed
12696059
uniprot
proteins
pubmed
12857874
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15601896
uniprot
proteins
pubmed
16148947
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19761540
uniprot
proteins
pubmed
20682791
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
637
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome {ECO:0000269|PubMed:20682791}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:12857874}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:12857874}. Recycling endosome membrane {ECO:0000269|PubMed:15601896}; Peripheral membrane protein. Cleavage furrow {ECO:0000269|PubMed:15601896}. Midbody {ECO:0000269|PubMed:12857874, ECO:0000269|PubMed:15601896}. Cytoplasmic vesicle {ECO:0000269|PubMed:15601896}. Note=Recruited to the cleavage furrow and the midbody during cytokinesis. {ECO:0000269|PubMed:15601896}.
uniprot
proteins