E2F2
entrez
1870
canonical
uniprot
Q14209
canonical
ensembl
ENSG00000007968
resolver
ensembl
ENSG00000282899
resolver
ensp
ENSP00000355249
resolver
ensp
ENSP00000489612
resolver
ensp
ENSP00000585390
resolver
enst
ENST00000361729
resolver
enst
ENST00000634683
resolver
genesymbol
E2F2
resolver
hgnc
HGNC:3114
resolver
uniprot
B2R9W1
resolver
uniprot
Q7Z6H1
resolver
uniprot_entry
E2F2_HUMAN
resolver
uniprot_sec
B2R9W1
resolver
uniprot_sec
Q7Z6H1
resolver
amino_acid_sequence
MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPGTCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
uniprot
proteins
function
FUNCTION: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.
uniprot
proteins
mass_dalton
47506
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase. {ECO:0000250}.
uniprot
proteins
protein_family
E2F/DP family
uniprot
proteins
pubmed
12502741
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15716352
uniprot
proteins
pubmed
16360038
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
8246995
uniprot
proteins
sequence_length
437
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins