Afg1l
entrez
215951
canonical
uniprot
Q3V384
canonical
ensembl
ENSMUSG00000038302
resolver
ensp
ENSMUSP00000036149
resolver
ensp
ENSMUSP00000120389
resolver
enst
ENSMUST00000041024
resolver
genesymbol
Afg1l
resolver
genesymbol_syn
Lace1
resolver
uniprot
Q5EBH5
resolver
uniprot
Q8K1E9
resolver
uniprot_entry
AFG1L_MOUSE
resolver
uniprot_sec
Q5EBH5
resolver
uniprot_sec
Q8K1E9
resolver
amino_acid_sequence
MAASWSPLVTLRSAARSRLTGRGVGCGARVVAIPPPAPGPGKPLWKAYTVQTSEGVRPTAASEARLKALAVCHGPLDHYDFLIKSQELREDEHQRRVVQCLQKLQEDLKGYSIEEGGLFSKLFSRNKPPKGLYVYGDVGTGKTMVMDMFYAYVETKRKKRVHFHGFMLDVHRRIHHLKQSLPKRKAGFMAKSYDPIAPIAEEISQETSLLCFDEFQVTDIADAMILKQLFENLFKNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKEYCDTLQLDSGVDYRKRELAPAGKLYYLTSEADVEAVVDKLFDELAQKQNDLTSPRILKVQGRELRLNKACGSVADCTFEELCERPLGASDYLELSKNFDTVIIRNIPQFSLAKRTQARRFITLIDNFYDFKVRIICSASAPISSLFLHQHQDSESDQSRILMDDLGLSQDSAGLSMFTGEEEIFAFQRTISRLTEMQTEQYWIEGDRSRK
uniprot
proteins
ec_number
3.6.-.-
uniprot
proteins
function
FUNCTION: Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain. Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress. {ECO:0000250|UniProtKB:Q8WV93}.
uniprot
proteins
mass_dalton
54313
uniprot
proteins
protein_family
AFG1 ATPase family
uniprot
proteins
pubmed
12079282
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
480
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:Q8WV93}.
uniprot
proteins