Dusp29
entrez
361003
canonical
uniprot
P0C595
canonical
ensembl
ENSRNOG00000013034
resolver
ensembl
ENSRNOG00055018924
resolver
ensembl
ENSRNOG00060012328
resolver
ensembl
ENSRNOG00065010213
resolver
ensp
ENSRNOP00000017483
resolver
ensp
ENSRNOP00000110191
resolver
ensp
ENSRNOP00055026116
resolver
ensp
ENSRNOP00060016470
resolver
ensp
ENSRNOP00065012506
resolver
enst
ENSRNOT00000124521
resolver
enst
ENSRNOT00055032269
resolver
enst
ENSRNOT00060020895
resolver
enst
ENSRNOT00065016461
resolver
genesymbol
Dusp29
resolver
genesymbol_syn
Dupd1
resolver
uniprot
A0ABK0M0H1
resolver
uniprot_entry
A0ABK0M0H1_RAT
resolver
uniprot_entry
DUS29_RAT
resolver
amino_acid_sequence
MASGDTKTSVKHAHPCAERLSLQQEEGEAEDYCTPGAFELERLFWKGSPQYTHVNEVWPRLHVGDEATALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRDMAIEYHGVEADDVPTFDLSIFFYSAAAFIDSALQDDHSKILVHCAMGRSRSATLVLAYLMIHKNMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVKQRRQAGPGAGELGL
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase. Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity). {ECO:0000250|UniProtKB:Q68J44, ECO:0000250|UniProtKB:Q8BK84}.
uniprot
proteins
mass_dalton
24073
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
215
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q68J44}. Nucleus {ECO:0000250|UniProtKB:Q8BK84}.
uniprot
proteins