Hmx3
entrez
15373
canonical
uniprot
P42581
canonical
ensembl
ENSMUSG00000040148
resolver
ensp
ENSMUSP00000039018
resolver
enst
ENSMUST00000046093
resolver
genesymbol
Hmx3
resolver
genesymbol_syn
Nkx-5.1
resolver
genesymbol_syn
Nkx5-1
resolver
uniprot
B9EIJ0
resolver
uniprot
O88699
resolver
uniprot_entry
HMX3_MOUSE
resolver
uniprot_sec
B9EIJ0
resolver
uniprot_sec
O88699
resolver
amino_acid_sequence
MPEPGPDASGTASAPPPQPPPQPPAPKESPFSIRNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATTATPGSEDWKAGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV
uniprot
proteins
function
FUNCTION: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS. {ECO:0000269|PubMed:15363417, ECO:0000269|PubMed:9389661, ECO:0000269|PubMed:9435283}.
uniprot
proteins
mass_dalton
37859
uniprot
proteins
mutagenesis
MUTAGEN 276; /note="Q->K: Abolishes DNA-binding."; /evidence="ECO:0000269|PubMed:10206974
uniprot
proteins
protein_family
HMX homeobox family
uniprot
proteins
pubmed
10206974
uniprot
proteins
pubmed
10543441
uniprot
proteins
pubmed
11731242
uniprot
proteins
pubmed
11748138
uniprot
proteins
pubmed
12874121
uniprot
proteins
pubmed
14695375
uniprot
proteins
pubmed
15363417
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7510254
uniprot
proteins
pubmed
8541222
uniprot
proteins
pubmed
8970821
uniprot
proteins
pubmed
9389661
uniprot
proteins
pubmed
9435283
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins