LRCH1
entrez
23143
canonical
uniprot
Q9Y2L9
canonical
ensembl
ENSG00000136141
resolver
ensp
ENSP00000308493
resolver
ensp
ENSP00000374447
resolver
ensp
ENSP00000374448
resolver
genesymbol
LRCH1
resolver
genesymbol_syn
CHDC1
resolver
genesymbol_syn
KIAA1016
resolver
hgnc
HGNC:20309
resolver
uniprot
B7ZLL5
resolver
uniprot
F8W6F0
resolver
uniprot
Q17R43
resolver
uniprot
Q2KHR1
resolver
uniprot
Q5TBU9
resolver
uniprot
Q7Z5F6
resolver
uniprot
Q7Z5F7
resolver
uniprot_entry
LRCH1_HUMAN
resolver
uniprot_sec
B7ZLL5
resolver
uniprot_sec
F8W6F0
resolver
uniprot_sec
Q17R43
resolver
uniprot_sec
Q2KHR1
resolver
uniprot_sec
Q5TBU9
resolver
uniprot_sec
Q7Z5F6
resolver
uniprot_sec
Q7Z5F7
resolver
amino_acid_sequence
MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGAGGGGGGSGGFNLPLNRGLERALEEAANSGGLNLSARKLKEFPRTAAPGHDLSDTVQADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLSLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNVPMSNIMEEEQIIKEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNSGEERDQFTDRADGLHSEFMNYKARAEDCEELLRIEEDVHWQTEGIISSSKDQDMDIAMIEQLREAVDLLQDPNGLSTDITERSVLNLYPMGSAEALELQDSALNGQIQLETSPVCEVQSDLTLQSNGSQYSPNEIRENSPAVSPTTNSTAPFGLKPRSVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEADLCSPCDILQLDFRHIRKTVDTLLALGEKAPPPTSALRSRDLIGFCLVHILFIVLVYITYHWNALSA
uniprot
proteins
function
FUNCTION: Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration. {ECO:0000269|PubMed:28028151}.
uniprot
proteins
mass_dalton
80875
uniprot
proteins
pubmed
10231032
uniprot
proteins
pubmed
12168954
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28028151
uniprot
proteins
sequence_length
728
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:28028151}.
uniprot
proteins