AGPAT3
entrez
56894
canonical
uniprot
Q9NRZ7
canonical
ensembl
ENSG00000160216
resolver
ensp
ENSP00000291572
resolver
ensp
ENSP00000381135
resolver
ensp
ENSP00000381138
resolver
ensp
ENSP00000381140
resolver
ensp
ENSP00000678473
resolver
ensp
ENSP00000678478
resolver
ensp
ENSP00000678479
resolver
ensp
ENSP00000679330
resolver
ensp
ENSP00000679335
resolver
genesymbol
AGPAT3
resolver
genesymbol_syn
LPAAT3
resolver
hgnc
HGNC:326
resolver
uniprot
D3DSL2
resolver
uniprot
Q3ZCU2
resolver
uniprot
Q6UWP6
resolver
uniprot
Q6ZUC6
resolver
uniprot
Q8N3Q7
resolver
uniprot
Q9NRZ6
resolver
uniprot_entry
PLCC_HUMAN
resolver
uniprot_sec
D3DSL2
resolver
uniprot_sec
Q3ZCU2
resolver
uniprot_sec
Q6UWP6
resolver
uniprot_sec
Q6ZUC6
resolver
uniprot_sec
Q8N3Q7
resolver
uniprot_sec
Q9NRZ6
resolver
amino_acid_sequence
MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFKPARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE
uniprot
proteins
ec_number
2.3.1.51
uniprot
proteins
function
FUNCTION: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:21173190). Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor (PubMed:21173190). Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA (PubMed:21173190). Has a preference for arachidonoyl-CoA as a donor (By similarity). Also has a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity). {ECO:0000250|UniProtKB:Q9D517, ECO:0000269|PubMed:21173190}.
uniprot
proteins
mass_dalton
43381
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.
uniprot
proteins
protein_family
1-acyl-sn-glycerol-3-phosphate acyltransferase family
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
11487472
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
20537980
uniprot
proteins
pubmed
21173190
uniprot
proteins
sequence_length
376
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20537980, ECO:0000269|PubMed:21173190}; Multi-pass membrane protein {ECO:0000255}. Nucleus envelope {ECO:0000269|PubMed:21173190}.
uniprot
proteins
transmembrane_region
TRANSMEM 125..145; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 317..339; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins