Atp11b
entrez
76295
canonical
uniprot
Q6DFW5
canonical
ensembl
ENSMUSG00000037400
resolver
ensp
ENSMUSP00000029257
resolver
ensp
ENSMUSP00000307158
resolver
ensp
ENSMUSP00000328027
resolver
enst
ENSMUST00000029257
resolver
genesymbol
Atp11b
resolver
uniprot_entry
AT11B_MOUSE
resolver
amino_acid_sequence
MWRWVRQQLGFDPPHQSDTRTIYIANRFPQNGLYTPQKFIDNRIISSKYTIWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPITSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVSVPETAVLQTVANLDSLIAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLIILISEAIISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGLKYQEINGKLVPEGPSPDSTEGEVPFLGSLSHLSNSAHLTATSLRTSPESETELIKEHDLFFKAVSLCHTVQISNVQTDGIGDGPWQPNLAPAQLEYYASSPDEKALVEAAARAGIIFVGISEETMEVKVLGRLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIAKTRIHVDEFALKGLRTLCIAYRQFTAKEYEDVDRRLFEARTALQHREEKLADAFQYIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSGCAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPVLIYSLVEQHIDPHVLQSKPTLYRDISKNGLLSIKAFLYWTVLGFSHAFIFFFGSYFLVGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFIFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAILLMVVTCLFIDVVKKVFDRQLHPTSTEKAQLAEAHSSVKCLDSVCCFPGETPCASVGRMLERVIGRCSPNHISRLWNASDPFYTNDRSILTLSPMDSSTC
uniprot
proteins
ec_number
7.6.2.1
uniprot
proteins
function
FUNCTION: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes. May contribute to the maintenance of membrane lipid asymmetry in endosome compartment. {ECO:0000250|UniProtKB:Q9Y2G3}.
uniprot
proteins
mass_dalton
133536
uniprot
proteins
protein_family
Cation transport ATPase (P-type) (TC 3.A.3) family
uniprot
proteins
protein_family
Type IV subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30018401
uniprot
proteins
sequence_length
1175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Recycling endosome membrane {ECO:0000250|UniProtKB:Q9Y2G3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Y2G3}. Early endosome {ECO:0000250|UniProtKB:Q9Y2G3}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9Y2G3}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q9Y2G3}. Note=Exit from the endoplasmic reticulum requires the presence of CDC50A, but not CDC50B. In the presence of CDC50A, mainly located in recycling endosomes. {ECO:0000250|UniProtKB:Q9Y2G3}.
uniprot
proteins
transmembrane_region
TRANSMEM 69..89; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 91..111; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 287..307; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 338..358; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 862..882; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 910..930; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 963..983; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 994..1014; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1033..1053; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1060..1080; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins