GPRC5D
entrez
55507
canonical
uniprot
Q9NZD1
canonical
ensembl
ENSG00000111291
resolver
ensp
ENSP00000228887
resolver
ensp
ENSP00000379624
resolver
genesymbol
GPRC5D
resolver
hgnc
HGNC:13310
resolver
uniprot
Q3KNV3
resolver
uniprot
Q7Z5J9
resolver
uniprot
Q8TDS6
resolver
uniprot_entry
GPC5D_HUMAN
resolver
uniprot_sec
Q3KNV3
resolver
uniprot_sec
Q7Z5J9
resolver
uniprot_sec
Q8TDS6
resolver
amino_acid_sequence
MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLLLAFLFLMRKIQDCSQWNVLPTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFALCFSCLLAHASNLVKLVRGCVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRGMMFVNMTPCQLNVDFVVLLVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFITVLFSIIIWVVWISMLLRGNPQFQRQPQWDDPVVCIALVTNAWVFLLLYIVPELCILYRSCRQECPLQGNACPVTAYQHSFQVENQELSRARDSDGAEEDVALTSYGTPIQPQTVDPTQECFIPQAKLSPQQDAGGV
uniprot
proteins
function
FUNCTION: G protein-coupled receptor involved in hard keratin expression and likely plays a role in the development of hair and nails. {ECO:0000269|PubMed:15086536}.
uniprot
proteins
mass_dalton
38791
uniprot
proteins
protein_family
G protein-coupled receptor 3 family
uniprot
proteins
pubmed
11311935
uniprot
proteins
pubmed
12044878
uniprot
proteins
pubmed
15086536
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
38898050
uniprot
proteins
pubmed
39181182
uniprot
proteins
sequence_length
345
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11311935}; Multi-pass membrane protein {ECO:0000269|PubMed:11311935}.
uniprot
proteins
transmembrane_region
TRANSMEM 28..48; /note="Helical; Name=1"; /evidence="ECO:0000269|PubMed:38898050, ECO:0000269|PubMed:39181182, ECO:0007744|PDB:8YZK, ECO:0007744|PDB:9IMA"; TRANSMEM 64..84; /note="Helical; Name=2"; /evidence="ECO:0000269|PubMed:38898050, ECO:0000269|PubMed:39181182, ECO:0007744|PDB:8YZK, ECO:0007744|PDB:9IMA"; TRANSMEM 94..114; /note="Helical; Name=3"; /evidence="ECO:0000269|PubMed:38898050, ECO:0000269|PubMed:39181182, ECO:0007744|PDB:8YZK, ECO:0007744|PDB:9IMA"; TRANSMEM 124..144; /note="Helical; Name=4"; /evidence="ECO:0000269|PubMed:38898050, ECO:0000269|PubMed:39181182, ECO:0007744|PDB:8YZK, ECO:0007744|PDB:9IMA"; TRANSMEM 168..188; /note="Helical; Name=5"; /evidence="ECO:0000269|PubMed:38898050, ECO:0000269|PubMed:39181182, ECO:0007744|PDB:8YZK, ECO:0007744|PDB:9IMA"; TRANSMEM 205..225; /note="Helical; Name=6"; /evidence="ECO:0000269|PubMed:38898050, ECO:0000269|PubMed:39181182, ECO:0007744|PDB:8YZK, ECO:0007744|PDB:9IMA"; TRANSMEM 240..260; /note="Helical; Name=7"; /evidence="ECO:0000269|PubMed:38898050, ECO:0000269|PubMed:39181182, ECO:0007744|PDB:8YZK, ECO:0007744|PDB:9IMA
uniprot
proteins