STON2
entrez
85439
canonical
uniprot
Q8WXE9
canonical
ensembl
ENSG00000140022
resolver
ensp
ENSP00000450577
resolver
ensp
ENSP00000450857
resolver
ensp
ENSP00000477736
resolver
ensp
ENSP00000498075
resolver
ensp
ENSP00000534064
resolver
ensp
ENSP00000534065
resolver
enst
ENST00000553821
resolver
enst
ENST00000614646
resolver
enst
ENST00000649389
resolver
genesymbol
STON2
resolver
genesymbol_syn
STN2
resolver
genesymbol_syn
STNB
resolver
hgnc
HGNC:30652
resolver
uniprot
A0A3B3IU55
resolver
uniprot
G3V2T7
resolver
uniprot
H0YJ05
resolver
uniprot
Q17R24
resolver
uniprot
Q59H11
resolver
uniprot
Q6NT47
resolver
uniprot
Q96RI7
resolver
uniprot
Q96RU6
resolver
uniprot_entry
A0A3B3IU55_HUMAN
resolver
uniprot_entry
H0YJ05_HUMAN
resolver
uniprot_entry
STON2_HUMAN
resolver
uniprot_sec
G3V2T7
resolver
uniprot_sec
Q17R24
resolver
uniprot_sec
Q59H11
resolver
uniprot_sec
Q6NT47
resolver
uniprot_sec
Q96RI7
resolver
uniprot_sec
Q96RU6
resolver
amino_acid_sequence
MTTLDHVIATHQSEWVSFNEEPPFPAHSQGGTEEHLPGLSSSPDQSESSSGENHVVDGGSQDHSHSEQDDSSEKMGLISEAASPPGSPEQPPPDLASAISNWVQFEDDTPWASTSPPHQETAETALPLTMPCWTCPSFDSLGRCPLTSESSWTTHSEDTSSPSFGCSYTDLQLINAEEQTSGQASGADSTDNSSSLQEDEEVEMEAISWQASSPAMNGHPAPPVTSARFPSWVTFDDNEVSCPLPPVTSPLKPNTPPSASVIPDVPYNSMGSFKKRDRPKSTLMNFSKVQKLDISSLNRTPSVTEASPWRATNPFLNETLQDVQPSPINPFSAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQIDDPDHFGSATLPDDDPVAWIELDAHPPGSARSQPRDGWPMMLRIPEKKNIMSSRHWGPIFVKLTDTGYLQLYYEQGLEKPFREFKLEICHEISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHTAEREQVIKLGTTNYDDFLSFIHAVQDRLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGIVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILVKGNEIVLRQDIMPTTTTKWIKLHECRFHGCVDEDVFHNSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDPLTQVPCENVMIRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKASVRSISVEDKTDVRKWVNYSAHYSYQVALGSIWLMLPTPFVHPTTLPLLFLLAMLTMFAW
uniprot
proteins
function
FUNCTION: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating. {ECO:0000269|PubMed:11381094, ECO:0000269|PubMed:11454741, ECO:0000269|PubMed:21102408}.
uniprot
proteins
mass_dalton
101165
uniprot
proteins
mutagenesis
MUTAGEN 738; /note="W->A: Reduces interaction with SYT1."; /evidence="ECO:0000269|PubMed:11454741"; MUTAGEN 740; /note="K->A: Reduces interaction with SYT1."; /evidence="ECO:0000269|PubMed:11454741
uniprot
proteins
post_translational_modification
PTM: Phosphorylated in vitro by PKD. {ECO:0000269|PubMed:21102408}.; PTM: Neddylated; deneddylated via its interaction with the COP9 signalosome (CSN) complex through TOR1A and COPS4. {ECO:0000269|PubMed:21102408}.; PTM: Ubiquitinated; leading to its degradation. {ECO:0000269|PubMed:21102408}.
uniprot
proteins
protein_family
Stoned B family
uniprot
proteins
pubmed
11381094
uniprot
proteins
pubmed
11454741
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18200045
uniprot
proteins
pubmed
21102408
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
905
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11381094}. Membrane {ECO:0000269|PubMed:11381094}. Synapse, synaptosome {ECO:0000250}. Note=Some fraction is membrane-associated.
uniprot
proteins