Q63603
uniprot
Q63603
canonical
amino_acid_sequence
KLSRGHSPLMKKVFDVYLCFLQKHQSEMALKNVFTALRSLIYKFPSTFYEGRADMCASLCYEVLKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISLSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEADLALQREPPVFPYSHTSCQRKSRGGMFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERLRAGLLTSINSSSPSMKSGGTLETTHLYDTLHRPYSKVTEVITRAAGSWDLLPGGLFGQGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKFAYIQVTHVTPFFDEKELQERKTEFERCHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELHQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREIRKELSDIIVPRICPGEDKRATKFPAHLQRHQRDTNKHSGSRVDQFILSCVTLPHEPHVGTCFVMCKLRTTFRANHWFCQAQEEAMGNGREKEPGL
uniprot
proteins
function
FUNCTION: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation (By similarity). {ECO:0000250|UniProtKB:Q8BIK4, ECO:0000250|UniProtKB:Q9BZ29}.
uniprot
proteins
mass_dalton
82455
uniprot
proteins
protein_family
DOCK family
uniprot
proteins
sequence_length
720
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endomembrane system {ECO:0000305}. Note=Associated with membranes. {ECO:0000305}.
uniprot
proteins