Kcnv1
entrez
60326
canonical
uniprot
P97557
canonical
ensembl
ENSRNOG00000004117
resolver
ensembl
ENSRNOG00055024942
resolver
ensembl
ENSRNOG00060006771
resolver
ensembl
ENSRNOG00065003798
resolver
ensp
ENSRNOP00000005556
resolver
ensp
ENSRNOP00055035087
resolver
ensp
ENSRNOP00060008288
resolver
ensp
ENSRNOP00065004042
resolver
enst
ENSRNOT00000005556
resolver
enst
ENSRNOT00055042986
resolver
enst
ENSRNOT00060011096
resolver
enst
ENSRNOT00065005553
resolver
genesymbol
Kcnv1
resolver
uniprot_entry
KCNV1_RAT
resolver
amino_acid_sequence
MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCLTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSQGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNLQLLEILEYVCISWFTGEFILRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDIYARSIMEMLRLKGRERASTRSSGGDDFWF
uniprot
proteins
function
FUNCTION: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes (By similarity). {ECO:0000250, ECO:0000269|PubMed:9169526}.
uniprot
proteins
mass_dalton
56663
uniprot
proteins
protein_family
Kv8.1/KCNV1 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
protein_family
V (TC 1.A.1.2) subfamily
uniprot
proteins
pubmed
9169526
uniprot
proteins
sequence_length
503
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2 (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 214..234; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 242..262; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 280..300; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 313..334; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 349..369; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 410..430; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins