MRM3
entrez
55178
canonical
uniprot
Q9HC36
canonical
ensembl
ENSG00000171861
resolver
ensp
ENSP00000306080
resolver
enst
ENST00000304478
resolver
genesymbol
MRM3
resolver
genesymbol_syn
RNMTL1
resolver
hgnc
HGNC:18485
resolver
uniprot
Q53GN1
resolver
uniprot
Q86VC3
resolver
uniprot
Q96F76
resolver
uniprot
Q9NVQ5
resolver
uniprot_entry
MRM3_HUMAN
resolver
uniprot_sec
Q53GN1
resolver
uniprot_sec
Q86VC3
resolver
uniprot_sec
Q96F76
resolver
uniprot_sec
Q9NVQ5
resolver
amino_acid_sequence
MAALVRPARFVVRPLLQVVQAWDLDARRWVRALRRSPVKVVFPSGEVVEQKRAPGKQPRKAPSEASAQEQREKQPLEESASRAPSTWEESGLRYDKAYPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDKLKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDHVKMTYPKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADNCGLYAQAEMSNKASDHGWVCDQRVMKFHKYEEEEDVETGASQDWLPHVEVQSYDSDWTEAPAAVVIGGETYGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGRAEDLSRDRSYH
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA (PubMed:24036117, PubMed:25009282, PubMed:25074936, PubMed:35177605). Also required for formation of 2'-O-methyluridine at position 1369 (Um1369) mediated by MRM2 (PubMed:35177605). {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282, ECO:0000269|PubMed:25074936, ECO:0000269|PubMed:35177605}.
uniprot
proteins
mass_dalton
47020
uniprot
proteins
protein_family
Class IV-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
RNA methyltransferase TrmH family
uniprot
proteins
pubmed
12296377
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24036117
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25009282
uniprot
proteins
pubmed
25074936
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
35177605
uniprot
proteins
sequence_length
420
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282}.
uniprot
proteins