Fut1
entrez
14343
canonical
uniprot
O09160
canonical
ensembl
ENSMUSG00000008461
resolver
ensp
ENSMUSP00000008605
resolver
ensp
ENSMUSP00000147274
resolver
ensp
ENSMUSP00000341550
resolver
enst
ENSMUST00000008605
resolver
enst
ENSMUST00000209379
resolver
genesymbol
Fut1
resolver
uniprot
A0A1B0GQW1
resolver
uniprot
P97327
resolver
uniprot
Q32MG3
resolver
uniprot_entry
A0A1B0GQW1_MOUSE
resolver
uniprot_entry
FUT1_MOUSE
resolver
uniprot_entry
Q32MG3_MOUSE
resolver
uniprot_sec
P97327
resolver
amino_acid_sequence
MWTPSRRQLCLAFLLVCVLSAGSFFFHLNGGNFFRNGLTLSVLCSDYHLLKSPVAMVCLPHPLQTSNGSPSCPEQSSSLSGTWTITPGGRFGNQMGQYATLLALAQLNGRQAFIQPEMHAALAPVFRISLPVLDPEVDSLTPWQHLVLHDWMSEEYSHLEDPFLKLSGFPCSWTFFHHLREQIRREFTLHNHLREGAQYLLSGLRIGPAGIRPHTFVGVHVRRGDYLEVMPNRWKGVVGDRAYLQQAMDWFRARHKDPIFVVTSNGMKWCLENIDTSHGDVVFAGNGQEGTPGKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEFLKIFRPEAAFLPEWVGINADLSPLQAQFDPWKPDSLFRLV
uniprot
proteins
ec_number
2.4.1.344
uniprot
proteins
ec_number
2.4.1.69
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens (PubMed:11368156, PubMed:14967068, PubMed:16884711). H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis (PubMed:16884711). Preferentially fucosylates soluble lactose and to a lesser extent, fucosylates glycolipids gangliosides GA1 and GM1a (PubMed:11368156, PubMed:14967068). {ECO:0000269|PubMed:11368156, ECO:0000269|PubMed:14967068, ECO:0000269|PubMed:16884711}.
uniprot
proteins
mass_dalton
42394
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:P19526}.
uniprot
proteins
protein_family
Glycosyltransferase 11 family
uniprot
proteins
pubmed
11368156
uniprot
proteins
pubmed
11713270
uniprot
proteins
pubmed
14967068
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16884711
uniprot
proteins
pubmed
18379136
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
9355741
uniprot
proteins
sequence_length
377
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305|PubMed:11368156}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..26; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins