Galp
entrez
232836
canonical
uniprot
Q810H5
canonical
ensembl
ENSMUSG00000034660
resolver
ensp
ENSMUSP00000037408
resolver
genesymbol
Galp
resolver
uniprot
A5GXX4
resolver
uniprot_entry
GALP_MOUSE
resolver
uniprot_sec
A5GXX4
resolver
amino_acid_sequence
MACSVHLVLFLTILLSLAETPESAPAHRGRGGWTLNSAGYLLGPVLPVSSKADQGRKRDSALEILDLWKIIDGLPYSHSPRMTKRTMGETFVKANTGDMHILDKNVPKEEATLDSES
uniprot
proteins
function
FUNCTION: [Isoform 1]: Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion.; FUNCTION: [Isoform 2]: Exhibits antimicrobial activity against Gram-negative bacterias, inducing bacterial membrane blebbing (By similarity). Exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. {ECO:0000250, ECO:0000269|PubMed:12746327, ECO:0000269|PubMed:17535903}.
uniprot
proteins
mass_dalton
12773
uniprot
proteins
protein_family
Galanin family
uniprot
proteins
pubmed
12746327
uniprot
proteins
pubmed
17535903
uniprot
proteins
sequence_length
117
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
uniprot
proteins