Foxe1
entrez
110805
canonical
uniprot
Q8R2I0
canonical
ensembl
ENSMUSG00000070990
resolver
ensp
ENSMUSP00000092715
resolver
enst
ENSMUST00000095097
resolver
genesymbol
Foxe1
resolver
genesymbol_syn
Titf2
resolver
uniprot
A2AM00
resolver
uniprot_entry
FOXE1_MOUSE
resolver
uniprot_sec
A2AM00
resolver
amino_acid_sequence
MTAESAPPPPPQPETLAAVKEERGEAAAAGAGVPAEAAGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAIFPGAVPAARPAYPGAVYAGYAPPLAAPPPVYYPAASPGPCRVFGLVPERPLSPDLGPAPSAAGGSCAFAAAAGAAGTGSFQPAVCTGARPVNPAAYAAAYAGPDGAYPQGASSALFAAAAGRLAGPASPPAGGGSGGVEATVDFYGRTSPGQFGAALGPCYNPGGQLGAGGGGAYHSRHATAYPGAVDRFVSAM
uniprot
proteins
function
FUNCTION: Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor (PubMed:21177256). Also implicated in thyroid gland morphogenesis (PubMed:9697704). May indirectly play a role in cell growth and migration through the regulation of WNT5A expression (By similarity). {ECO:0000250|UniProtKB:O00358, ECO:0000269|PubMed:21177256, ECO:0000269|PubMed:9697704}.
uniprot
proteins
mass_dalton
37768
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000269|PubMed:12203737}.
uniprot
proteins
pubmed
12203737
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21177256
uniprot
proteins
pubmed
9697704
uniprot
proteins
sequence_length
371
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O00358}.
uniprot
proteins