OSGEPL1
entrez
64172
canonical
uniprot
Q9H4B0
canonical
ensembl
ENSG00000128694
resolver
ensp
ENSP00000264151
resolver
ensp
ENSP00000538857
resolver
ensp
ENSP00000607504
resolver
ensp
ENSP00000607505
resolver
ensp
ENSP00000607506
resolver
ensp
ENSP00000673990
resolver
ensp
ENSP00000708244
resolver
ensp
ENSP00000708245
resolver
ensp
ENSP00000708246
resolver
genesymbol
OSGEPL1
resolver
genesymbol_syn
GCP1
resolver
hgnc
HGNC:23075
resolver
uniprot
Q96EV9
resolver
uniprot
Q96NH5
resolver
uniprot_entry
OSGL1_HUMAN
resolver
uniprot_sec
Q96EV9
resolver
uniprot_sec
Q96NH5
resolver
amino_acid_sequence
MLILTKTAGVFFKPSKRKVYEFLRSFNFHPGTLFLHKIVLGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGVSPSDLSAIATTIKPGLALSLGVGLSFSLQLVGQLKKPFIPIHHMEAHALTIRLTNKVEFPFLVLLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQGNRFHFDIKPPLHHAKNCDFSFTGLQHVTDKIIMKKEKEEGIEKGQILSSAADIAATVQHTMACHLVKRTHRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPRLCTDNGIMIAWNGIERLRAGLGILHDIEGIRYEPKCPLGVDISKEVGEASIKVPQLKMEI
uniprot
proteins
ec_number
2.3.1.234
uniprot
proteins
function
FUNCTION: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. {ECO:0000255|HAMAP-Rule:MF_03179, ECO:0000269|PubMed:29760464, ECO:0000269|PubMed:32047918}.
uniprot
proteins
mass_dalton
45123
uniprot
proteins
mutagenesis
MUTAGEN 203; /note="K->Q: Mimics acetylation; decreased formation of tRNA threonylcarbamoyladenosine modification."; /evidence="ECO:0000269|PubMed:32047918"; MUTAGEN 299; /note="K->Q: Mimics acetylation; increased formation of tRNA threonylcarbamoyladenosine modification."; /evidence="ECO:0000269|PubMed:32047918
uniprot
proteins
protein_family
KAE1 / TsaD family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
19694617
uniprot
proteins
pubmed
29760464
uniprot
proteins
pubmed
32047918
uniprot
proteins
sequence_length
414
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03179, ECO:0000269|PubMed:19694617, ECO:0000269|PubMed:29760464}.
uniprot
proteins