Tspyl5
entrez
239364
canonical
uniprot
Q69ZB3
canonical
ensembl
ENSMUSG00000038984
resolver
ensp
ENSMUSP00000045542
resolver
enst
ENSMUST00000042021
resolver
genesymbol
Tspyl5
resolver
genesymbol_syn
Kiaa1750
resolver
uniprot_entry
TSYL5_MOUSE
resolver
amino_acid_sequence
MSGRSRGRKSSRAKGRGKGRARARVRAAAEDAWHDEKPPQSPRLGEDSAAAQVQAGAAQGGAEPAELREEAACRLPLDCGLALRARAADERGLAAPDPDLERARSLAERLTSDTSFVGTVGALAKLRRGSRIGNRRVPGRKAPDTRSATGRGPQATVSGKPKMASAGLCAAAPVGEEKKMTEKHAGAGSPATVGSMDTLETVQLKLETMNAQADRAYLRLSRKFGQLRLHHLERRNLLIQSIPGFWGQAFQNHPQLSAFLNTKDKEVLSYLNRLEVEELGLARLGYKIKFYFGRNPYFQNKVLIKEYGCGPSGQVVSRSAPIQWLPGHDLQSLSKENPENNGSFFGWFSNHSSIESDKIVEIINEDLWPNPLQYYLISEEARGEKGKEERPGPAKLSPAPAVRQPN
uniprot
proteins
function
FUNCTION: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
44303
uniprot
proteins
protein_family
Nucleosome assembly protein (NAP) family
uniprot
proteins
pubmed
15368895
uniprot
proteins
sequence_length
406
uniprot
proteins