Gpha2
entrez
170458
canonical
uniprot
Q925Q5
canonical
ensembl
ENSMUSG00000024784
resolver
ensp
ENSMUSP00000025698
resolver
ensp
ENSMUSP00000109154
resolver
enst
ENSMUST00000025698
resolver
enst
ENSMUST00000113526
resolver
genesymbol
Gpha2
resolver
genesymbol_syn
Gpa2
resolver
genesymbol_syn
Zsig51
resolver
uniprot
A2RSW3
resolver
uniprot_entry
A2RSW3_MOUSE
resolver
uniprot_entry
GPHA2_MOUSE
resolver
amino_acid_sequence
MPMAPRVLLLCLLGLAVTEGHSPETAIPGCHLHPFNVTVRSDRLGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSSSQCCTISSLRKVRVWLQCVGNQRGELEIFTARACQCDMCRFSRY
uniprot
proteins
function
FUNCTION: Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. {ECO:0000250|UniProtKB:Q96T91}.
uniprot
proteins
mass_dalton
14030
uniprot
proteins
protein_family
Glycoprotein hormones subunit alpha family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
128
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
uniprot
proteins