Riox2
entrez
67014
canonical
uniprot
Q8CD15
canonical
ensembl
ENSMUSG00000022724
resolver
ensp
ENSMUSP00000023407
resolver
ensp
ENSMUSP00000125297
resolver
ensp
ENSMUSP00000274497
resolver
enst
ENSMUST00000023407
resolver
enst
ENSMUST00000160571
resolver
genesymbol
Riox2
resolver
genesymbol_syn
Mina
resolver
genesymbol_syn
Mina53
resolver
uniprot
Q8QZX1
resolver
uniprot
Q9CQ03
resolver
uniprot_entry
RIOX2_MOUSE
resolver
uniprot_sec
Q8QZX1
resolver
uniprot_sec
Q9CQ03
resolver
amino_acid_sequence
MPKKVQPTGDENEEASVPCKRVKEELPETLSVLNFDSPSSFFESLISPIKVETFFKEFWEQKPLLIQRDDPVLAKYYQSLFSLSDLKRLCKKGVYYGRDVNVCRSISGKKKVLNKDGRAHFLQLRKDFDQKRATIQFHQPQRYKDELWRIQEKLECYFGSLVGSNVYMTPAGSQGLPPHYDDVEVFILQLEGTKHWRLYSPTVPLAHEYSVESEDRIGTPTHDFLLKPGDLLYFPRGTIHQAETPSGLAYSIHLTISTYQNNSWGDCLLDSISGFVFDIAKEDVALRSGMPRRMLLNVETPADVTRKLSGFLRTLADQLEGREELLSSDMKKDFVKHRLPPFFEGNGTETMDPGKQLPRLDNIIRLQFKDHIVLTVGPDKNPFDEAQQKVVYIYHSLKNVRQMHMIGEEEESEIFGLRFPLSHVDALKQIWCGSPIRVKDLKLDTDEEKENLALSLWSESLIQVL
uniprot
proteins
ec_number
1.14.11.79
uniprot
proteins
function
FUNCTION: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39' (By similarity). May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. {ECO:0000250, ECO:0000269|PubMed:16533354}.
uniprot
proteins
mass_dalton
53517
uniprot
proteins
protein_family
MINA53 subfamily
uniprot
proteins
protein_family
ROX family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16533354
uniprot
proteins
sequence_length
465
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16533354}. Nucleus, nucleolus {ECO:0000269|PubMed:16533354}.
uniprot
proteins