Col8a2
entrez
329941
canonical
uniprot
P25318
canonical
ensembl
ENSMUSG00000056174
resolver
ensp
ENSMUSP00000070270
resolver
genesymbol
Col8a2
resolver
uniprot
A3KFY2
resolver
uniprot
Q68ED0
resolver
uniprot
Q6KAQ4
resolver
uniprot
Q6P1C4
resolver
uniprot_entry
CO8A2_MOUSE
resolver
uniprot_sec
A3KFY2
resolver
uniprot_sec
Q68ED0
resolver
uniprot_sec
Q6KAQ4
resolver
uniprot_sec
Q6P1C4
resolver
amino_acid_sequence
MQGALMPLPSLLLLLLGCGPRVSSGGGAGGAAGYAPVKYVQPMQKGPVGPPFREGKGQYLEMPLPMLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGTGKPGVHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITVPGKPGAQGAPGPPGFRGEPGPQGEPGPRGDRGLKGDNGVGQPGLPGAPGQAGAPGPPGLPGPAGLGKPGLDGIPGAPGDKGDSGPPGVPGSRGEPGAVGPKGPPGVDGVGIPGAAGVPGPQGPVGAKGEPGLRGPPGLIGPVGYGMPGKPGPKGDRGPVGAPGLLGDRGEPGEDGKPGEQGPQGLGGPPGLPGSAGLPGRRGPPGSKGEVGPGGPPGVPGIRGDQGPNGLAGKPGLPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGKVGEPGSAGPTGPPGVPGSPGLTGPPGPPGPPGPPGAPGALDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVRFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT
uniprot
proteins
function
FUNCTION: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also a component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity). {ECO:0000250, ECO:0000269|PubMed:19401424}.
uniprot
proteins
mass_dalton
66943
uniprot
proteins
post_translational_modification
PTM: Proteolytically cleaved by neutrophil elastase, in vitro. {ECO:0000250}.; PTM: Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
uniprot
proteins
pubmed
15449545
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19401424
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
2019595
uniprot
proteins
sequence_length
699
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix, basement membrane.
uniprot
proteins