Arl6ip5
entrez
66028
canonical
uniprot
Q9ES40
canonical
ensembl
ENSRNOG00000006818
resolver
ensembl
ENSRNOG00055003864
resolver
ensembl
ENSRNOG00060004182
resolver
ensembl
ENSRNOG00065023811
resolver
ensp
ENSRNOP00000010185
resolver
ensp
ENSRNOP00000106824
resolver
ensp
ENSRNOP00055004641
resolver
ensp
ENSRNOP00060005271
resolver
ensp
ENSRNOP00065033314
resolver
enst
ENSRNOT00000010185
resolver
enst
ENSRNOT00055006118
resolver
enst
ENSRNOT00060006981
resolver
enst
ENSRNOT00065040828
resolver
genesymbol
Arl6ip5
resolver
genesymbol_syn
Gtrap3-18
resolver
genesymbol_syn
Jwa
resolver
genesymbol_syn
Pra2
resolver
genesymbol_syn
Praf3
resolver
uniprot
Q9JKD1
resolver
uniprot_entry
PRAF3_RAT
resolver
uniprot_sec
Q9JKD1
resolver
amino_acid_sequence
MDVNLAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGFLSPFNMILGGIIVVLVFTGFVWAAHNKDILRRMKKQYPTAFVMVVMLASYFLISMFGGVMVFVFGITFPLLLMFIHASLRLRNLKNKLENKMEGIGLKKTPMGIILDALEQQEDSINKFADYISKARE
uniprot
proteins
function
FUNCTION: Regulates intracellular concentrations of taurine and glutamate (Ref.5). Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner (PubMed:11242046). Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum (PubMed:19720795). {ECO:0000269|PubMed:11242046, ECO:0000269|PubMed:19720795, ECO:0000269|Ref.5, ECO:0000303|PubMed:11096102}.
uniprot
proteins
mass_dalton
21549
uniprot
proteins
mutagenesis
MUTAGEN 140..151; /note="RLRNLKNKLENK->ELENLENELENE: Partial relocalization to Golgi membranes."; /evidence="ECO:0000269|PubMed:11096102"; MUTAGEN 140..147; /note="RLRNLKNK->ALANLANA: No effect."; /evidence="ECO:0000269|PubMed:11096102"; MUTAGEN 185; /note="K->A: Partial relocalization to Golgi membranes."; /evidence="ECO:0000269|PubMed:11096102"; MUTAGEN 187; /note="R->A: Partial relocalization to Golgi membranes."; /evidence="ECO:0000269|PubMed:11096102
uniprot
proteins
protein_family
PRA1 family
uniprot
proteins
pubmed
11096102
uniprot
proteins
pubmed
11242046
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19720795
uniprot
proteins
sequence_length
188
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:11096102}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:11242046}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:11242046}. Cytoplasm, cytoskeleton {ECO:0000269|Ref.5}. Note=Also exists as a soluble form in the cytoplasm (PubMed:11242046). Associated with microtubules (Ref.5). {ECO:0000269|PubMed:11242046, ECO:0000269|Ref.5}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..56; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 57..77; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 93..113; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 115..135; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins