Slc25a30
entrez
361074
canonical
uniprot
Q5PQM9
canonical
ensembl
ENSRNOG00000001052
resolver
ensp
ENSRNOP00000097957
resolver
enst
ENSRNOT00000104191
resolver
genesymbol
Slc25a30
resolver
genesymbol_syn
Kmcp1
resolver
uniprot_entry
KMCP1_RAT
resolver
amino_acid_sequence
MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFREIRYRGMLHALMRIGREEGLRALYSGIAPAMLRQASYGTIKIGTYQSLKRLAVERPEDETLLINVVCGILSGVISSAIANPTDVLKIRMQAQNSAVQGGMIGNFISIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVSTHFLSSFTCGLVGALASNPVDVVRTRMMNQRDLRDGRCSGYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFLTYEQLKKLDL
uniprot
proteins
function
FUNCTION: Antiporter that transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate. The sulfate/sulfate exchange is much higher than the phosphate/phosphate and malate/malate exchanges. The transport affinities is higher for sulfate and thiosulfate than for any other substrate. May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide. Also may mediate a very low unidirectional transport of sulfate, phosphate and (S)-malate. {ECO:0000250|UniProtKB:Q5SVS4}.
uniprot
proteins
mass_dalton
32365
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9CR58}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..26; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 71..89; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 106..124; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 164..183; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 204..224; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 264..283; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins