Tyw3
entrez
209584
canonical
uniprot
Q8BSA9
canonical
ensembl
ENSMUSG00000047583
resolver
ensp
ENSMUSP00000057828
resolver
ensp
ENSMUSP00000131461
resolver
enst
ENSMUST00000052774
resolver
enst
ENSMUST00000170461
resolver
genesymbol
Tyw3
resolver
uniprot
E9PYE2
resolver
uniprot
Q8BSX2
resolver
uniprot_entry
E9PYE2_MOUSE
resolver
uniprot_entry
TYW3_MOUSE
resolver
uniprot_sec
Q8BSX2
resolver
amino_acid_sequence
MDRSAEFGRWKAQSLSKADLSRKGSVDEDAVEVVELLNSREEFFTTSSCAGRILLLDGSTEGSGVQKQHCCWLLVTHKPCARDDVMAALKGATSEAVLKFEPFILHVQCRTLQDAQTLHSVAIDSGFRNSGITVGKRGKTMLAVRGTHGLEVPLTHKGKLMVTEEYIEFLLTIANQKMEENKRRIGRFYNYLQHALKRETISNSHSKIKERNNPLCTHKNRRSQGKAQGPSTTEDNGRELEDGDGLEISAALFLGDD
uniprot
proteins
ec_number
2.1.1.282
uniprot
proteins
function
FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame. Catalyzes the methylation of 4-demethylwyosine, generating intermediates required for the formation of mature wybutosine. {ECO:0000250|UniProtKB:P53177}.
uniprot
proteins
mass_dalton
28575
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
uniprot
proteins
protein_family
TYW3 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
257
uniprot
proteins