Serpinb1c
entrez
380839
canonical
uniprot
Q5SV42
canonical
ensembl
ENSMUSG00000079049
resolver
ensp
ENSMUSP00000021834
resolver
ensp
ENSMUSP00000341471
resolver
enst
ENSMUST00000021834
resolver
genesymbol
Serpinb1c
resolver
uniprot
Q5SW82
resolver
uniprot
Q8K3Y1
resolver
uniprot_entry
ILEUC_MOUSE
resolver
uniprot_sec
Q5SW82
resolver
uniprot_sec
Q8K3Y1
resolver
amino_acid_sequence
MGQLSSANNLFALELFHTLNESNPTGNTIFSPVSISSALAMVYLGARGSTAAQLSKTLHFDSAEDIHSQFQSLTAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASIQKTYSADLALVDFQHASEDARKEINQWVKGQTEEKIQELFAVGVVDSMTKLVLVNATYFKGMWQKKFMARDTTDAPFRLSKKVTKTVKMMYLKNNLPFGYIPDLKCKVLEMPYQGGELSMVILLPEDIEDETTGLEEIEKQLTLEKLQECENLQNIDVCVKLPKFKMEESYILNSNLGQLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSYVEVNEEGTETDAAMPGTVVGCCLMPMEFTVDHPFLFFIRHNPTAHVLFLGRVCSP
uniprot
proteins
function
FUNCTION: Regulates the activity of the neutrophil proteases. Forms only a stable complex with CTSG/Cathepsin G (By similarity). During inflammation, limits the activity of inflammatory caspases CASP1 and CASP4 by suppressing their caspase-recruitment domain (CARD) oligomerization and enzymatic activation (PubMed:30692621). {ECO:0000250|UniProtKB:Q8VHP7, ECO:0000269|PubMed:30692621}.
uniprot
proteins
mass_dalton
41920
uniprot
proteins
protein_family
Ov-serpin subfamily
uniprot
proteins
protein_family
Serpin family
uniprot
proteins
pubmed
12189154
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
30692621
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins