CLEC18A
entrez
348174
canonical
uniprot
A5D8T8
canonical
ensembl
ENSG00000157322
resolver
ensp
ENSP00000288040
resolver
ensp
ENSP00000377304
resolver
ensp
ENSP00000454685
resolver
ensp
ENSP00000484176
resolver
ensp
ENSP00000559883
resolver
genesymbol
CLEC18A
resolver
genesymbol_syn
MRLP2
resolver
hgnc
HGNC:30388
resolver
uniprot
A8K1G9
resolver
uniprot
Q6DCB3
resolver
uniprot
Q7Z5K9
resolver
uniprot
Q96HH2
resolver
uniprot_entry
CL18A_HUMAN
resolver
uniprot_sec
A8K1G9
resolver
uniprot_sec
Q6DCB3
resolver
uniprot_sec
Q7Z5K9
resolver
uniprot_sec
Q96HH2
resolver
amino_acid_sequence
MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS
uniprot
proteins
function
FUNCTION: Binds polysaccharides in a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans (PubMed:26170455). {ECO:0000269|PubMed:26170455}.
uniprot
proteins
mass_dalton
49602
uniprot
proteins
mutagenesis
MUTAGEN 421; /note="D->N: Has a mild effect on polysaccharides binding."; /evidence="ECO:0000269|PubMed:26170455
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:26170455}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
26170455
uniprot
proteins
sequence_length
446
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26170455}. Endoplasmic reticulum {ECO:0000305|PubMed:26170455}. Golgi apparatus {ECO:0000305|PubMed:26170455}. Endosome {ECO:0000305|PubMed:26170455}.
uniprot
proteins