Tnfaip8
entrez
106869
canonical
uniprot
Q921Z5
canonical
ensembl
ENSMUSG00000062210
resolver
ensp
ENSMUSP00000119041
resolver
ensp
ENSMUSP00000120712
resolver
ensp
ENSMUSP00000136030
resolver
ensp
ENSMUSP00000136152
resolver
enst
ENSMUST00000148159
resolver
enst
ENSMUST00000148989
resolver
genesymbol
Tnfaip8
resolver
uniprot
D3YWJ5
resolver
uniprot
D3Z325
resolver
uniprot
Q3TQS5
resolver
uniprot
Q3U9V7
resolver
uniprot
Q3UBG8
resolver
uniprot
Q8BTH4
resolver
uniprot_entry
D3YWJ5_MOUSE
resolver
uniprot_entry
D3Z325_MOUSE
resolver
uniprot_entry
TFIP8_MOUSE
resolver
uniprot_sec
Q3TQS5
resolver
uniprot_sec
Q3U9V7
resolver
uniprot_sec
Q3UBG8
resolver
uniprot_sec
Q8BTH4
resolver
amino_acid_sequence
MLSEAEEPREVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHEIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI
uniprot
proteins
function
FUNCTION: Acts as a negative mediator of apoptosis. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
22960
uniprot
proteins
protein_family
TNFAIP8 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins