Grm6
entrez
108072
canonical
uniprot
Q5NCH9
canonical
ensembl
ENSMUSG00000000617
resolver
ensp
ENSMUSP00000000631
resolver
ensp
ENSMUSP00000130728
resolver
enst
ENSMUST00000000631
resolver
enst
ENSMUST00000171427
resolver
genesymbol
Grm6
resolver
genesymbol_syn
Gprc1f
resolver
genesymbol_syn
Mglur6
resolver
uniprot
A7MD55
resolver
uniprot
Q8CFQ7
resolver
uniprot_entry
A7MD55_MOUSE
resolver
uniprot_entry
GRM6_MOUSE
resolver
uniprot_entry
Q8CFQ7_MOUSE
resolver
amino_acid_sequence
MGRLRVLLLWLAWWLSQAGIAHGAGSVRLAGGLTLGGLFPVHARGAAGRACGTLKKEQGVHRLEAMLYALDRINADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGEEASVRCPGGVPPLRAAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFHKVIRRLMETPNARGIIIFANEDDIRRVLEATRQANLTGHFLWVGSDSWGSKISPILNLEEEAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGGQSDDSTRKCTGEERIGQDSTYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRTLLHYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAEALRLDMEALQWSGDPHEVPPSQCSLPCGPGERKKMVKGVPCCWHCEACDGYRFQVDEFTCEACPGHMRPTPNHTGCRPTPVVRLTWSSPWAALPLLLAVLGIMATTTIIATFMRHNDTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPCAAVCASRRLLLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFGLTSLQVVGVIAWLGAQPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKKTSTMAAPPKSENSEDAK
uniprot
proteins
function
FUNCTION: G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision. {ECO:0000250, ECO:0000269|PubMed:22131384, ECO:0000269|PubMed:9144650}.
uniprot
proteins
mass_dalton
95193
uniprot
proteins
protein_family
G protein-coupled receptor 3 family
uniprot
proteins
pubmed
18001285
uniprot
proteins
pubmed
18952919
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21832182
uniprot
proteins
pubmed
22131384
uniprot
proteins
pubmed
24114537
uniprot
proteins
pubmed
29590622
uniprot
proteins
pubmed
7889569
uniprot
proteins
pubmed
9144650
uniprot
proteins
sequence_length
871
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, dendrite {ECO:0000269|PubMed:21832182}. Note=Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane (By similarity). Detected at dendritic tips of bipolar cells (PubMed:21832182). {ECO:0000250, ECO:0000269|PubMed:21832182}.
uniprot
proteins
transmembrane_region
TRANSMEM 580..602; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 617..637; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 649..667; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 692..712; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 743..764; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 778..800; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 814..839; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins