Tada2a
entrez
360581
canonical
uniprot
Q6AYE3
canonical
ensembl
ENSRNOG00000002757
resolver
ensembl
ENSRNOG00055027251
resolver
ensembl
ENSRNOG00060023379
resolver
ensembl
ENSRNOG00065018986
resolver
ensp
ENSRNOP00000003699
resolver
ensp
ENSRNOP00000071555
resolver
ensp
ENSRNOP00000089252
resolver
ensp
ENSRNOP00055038904
resolver
ensp
ENSRNOP00060033852
resolver
ensp
ENSRNOP00065025588
resolver
enst
ENSRNOT00000003699
resolver
enst
ENSRNOT00000087769
resolver
enst
ENSRNOT00055047324
resolver
enst
ENSRNOT00060040916
resolver
enst
ENSRNOT00065032069
resolver
genesymbol
Tada2a
resolver
genesymbol_syn
Tada2l
resolver
uniprot
A0A0G2K0R7
resolver
uniprot
A1EC76
resolver
uniprot_entry
A0A0G2K0R7_RAT
resolver
uniprot_entry
TAD2A_RAT
resolver
uniprot_sec
A1EC76
resolver
amino_acid_sequence
MDRLGSFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHTYEIMTSDFPVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFINNPLFASTLLNLKQAEAAKTADTAIPFHSADDPPRPAFDSLLSRDMAGYMPARADFIEEFDNYAEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLVNLRKFRLMERRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSARTYDHLKKTREEERLKRTMLSEVLQYIQDSSACQQWLRRQADIDSGLSPSVLMASNSGRRSAPPLNLTGLPGTEKLNEKEKELCQVVRLVPGAYLEYKSALLNECHKQGGLRLAQARALIKIDVNKTRKIYDFLIREGYITKA
uniprot
proteins
function
FUNCTION: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage. {ECO:0000250|UniProtKB:O75478, ECO:0000250|UniProtKB:Q8CHV6}.
uniprot
proteins
mass_dalton
51399
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17218081
uniprot
proteins
sequence_length
443
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00624}. Chromosome {ECO:0000250|UniProtKB:Q8CHV6}.
uniprot
proteins