Pgap3
entrez
320655
canonical
uniprot
A2A559
canonical
ensembl
ENSMUSG00000038208
resolver
ensp
ENSMUSP00000088337
resolver
ensp
ENSMUSP00000119668
resolver
genesymbol
Pgap3
resolver
genesymbol_syn
Perld1
resolver
uniprot
A2A558
resolver
uniprot
Q3TCA8
resolver
uniprot_entry
PGAP3_MOUSE
resolver
uniprot_sec
A2A558
resolver
uniprot_sec
Q3TCA8
resolver
amino_acid_sequence
MAKRTAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEERNCSGDALKHFRSRQPIYMSLAGWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKWPFSRFLFIQEPASAVASLLNGLASLVMLCRYRASVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPSVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNRQRLPHTRRCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESGAMFKLD
uniprot
proteins
ec_number
3.1.1.-
uniprot
proteins
function
FUNCTION: Involved in the fatty acid remodeling steps of GPI-anchor maturation where the unsaturated acyl chain at sn-2 of inositol phosphate is replaced by a saturated stearoyl chain. May catalyze the first step of the fatty acid remodeling, by removing the unsaturated acyl chain at sn-2 of inositol phosphate, generating a lyso-GPI intermediate. The fatty acid remodeling steps is critical for the integration of GPI-APs into lipid rafts. {ECO:0000250|UniProtKB:A2V7M9}.
uniprot
proteins
mass_dalton
36528
uniprot
proteins
protein_family
PGAP3 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
320
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:A2V7M9}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 99..119; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 170..190; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 199..219; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 280..299; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins