Lias
entrez
79464
canonical
uniprot
Q99M04
canonical
ensembl
ENSMUSG00000029199
resolver
ensp
ENSMUSP00000031101
resolver
ensp
ENSMUSP00000113228
resolver
enst
ENSMUST00000031101
resolver
enst
ENSMUST00000122026
resolver
genesymbol
Lias
resolver
genesymbol_syn
LIAS
resolver
genesymbol_syn
Lip1
resolver
uniprot
A0A0M3HEP3
resolver
uniprot
Q543M1
resolver
uniprot_entry
A0A0M3HEP3_MOUSE
resolver
uniprot_entry
LIAS_MOUSE
resolver
uniprot_sec
Q543M1
resolver
amino_acid_sequence
MALRCWDTARSLGSRIFGRYAFTVRALSSLPDKKKEFLHNGPDLQDFVSGDLADKSTWDEYKGNLKRQKGERLRLPPWLKTKIPMGKNYNKLKNTLRNLSLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTARNPPPLDANEPDNTAKAIAEWGLDYVVLTSVDRDDVADGGAEHIAKTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRANFDQSLRVLRHAKEVQPDVVSKTSIMLGLGETDEQVYATLKALRAADVDCLTLGQYMQPTKRHLKVEEYVTPEKFKYWEKVGNELGFLYTASGPLVRSSYKAGEFFLKNLVARRKTKASKV
uniprot
proteins
ec_number
2.8.1.8
uniprot
proteins
function
FUNCTION: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000305}.
uniprot
proteins
mass_dalton
41879
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2. {ECO:0000255|HAMAP-Rule:MF_03123}.
uniprot
proteins
protein_family
Lipoyl synthase family
uniprot
proteins
protein_family
Radical SAM superfamily
uniprot
proteins
pubmed
11389890
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03123, ECO:0000269|PubMed:11389890}.
uniprot
proteins