ALDH3A1
entrez
218
canonical
uniprot
P30838
canonical
ensembl
ENSG00000108602
resolver
ensp
ENSP00000225740
resolver
ensp
ENSP00000388469
resolver
ensp
ENSP00000411821
resolver
ensp
ENSP00000460482
resolver
ensp
ENSP00000576020
resolver
ensp
ENSP00000576022
resolver
ensp
ENSP00000576025
resolver
ensp
ENSP00000576026
resolver
ensp
ENSP00000576027
resolver
ensp
ENSP00000616948
resolver
enst
ENST00000225740
resolver
enst
ENST00000444455
resolver
enst
ENST00000457500
resolver
enst
ENST00000494157
resolver
enst
ENST00000905961
resolver
enst
ENST00000905963
resolver
enst
ENST00000905966
resolver
enst
ENST00000905967
resolver
enst
ENST00000905968
resolver
enst
ENST00000946889
resolver
genesymbol
ALDH3A1
resolver
genesymbol_syn
ALDH3
resolver
hgnc
HGNC:405
resolver
uniprot
A8K828
resolver
uniprot
I3L3I9
resolver
uniprot
Q6PKA6
resolver
uniprot
Q9BT37
resolver
uniprot_entry
AL3A1_HUMAN
resolver
uniprot_entry
I3L3I9_HUMAN
resolver
uniprot_entry
Q6PKA6_HUMAN
resolver
uniprot_sec
A8K828
resolver
uniprot_sec
Q9BT37
resolver
amino_acid_sequence
MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
uniprot
proteins
ec_number
1.2.1.5
uniprot
proteins
function
FUNCTION: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). {ECO:0000250|UniProtKB:P47739, ECO:0000269|PubMed:1737758, ECO:0000305}.
uniprot
proteins
mass_dalton
50395
uniprot
proteins
mutagenesis
MUTAGEN 244; /note="C->S: Abolishes activity."; /evidence="ECO:0000269|PubMed:22021038
uniprot
proteins
protein_family
Aldehyde dehydrogenase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
1737758
uniprot
proteins
pubmed
1905102
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
2037078
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22021038
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
8493892
uniprot
proteins
pubmed
9250352
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P47739}.
uniprot
proteins