CEP170
entrez
9859
canonical
uniprot
Q5SW79
canonical
ensembl
ENSG00000143702
resolver
ensembl
ENSG00000276725
resolver
ensp
ENSP00000338161
resolver
ensp
ENSP00000355500
resolver
ensp
ENSP00000355501
resolver
ensp
ENSP00000355502
resolver
ensp
ENSP00000554345
resolver
ensp
ENSP00000602041
resolver
ensp
ENSP00000602042
resolver
ensp
ENSP00000626854
resolver
ensp
ENSP00000680569
resolver
ensp
ENSP00000680570
resolver
ensp
ENSP00000680571
resolver
ensp
ENSP00000680572
resolver
ensp
ENSP00000737538
resolver
ensp
ENSP00000737539
resolver
ensp
ENSP00000737540
resolver
ensp
ENSP00000737541
resolver
genesymbol
CEP170
resolver
genesymbol_syn
FAM68A
resolver
genesymbol_syn
KAB
resolver
genesymbol_syn
KIAA0470
resolver
hgnc
HGNC:28920
resolver
uniprot
O75058
resolver
uniprot
Q5SW77
resolver
uniprot
Q5SW78
resolver
uniprot
Q7LGA9
resolver
uniprot
Q86W31
resolver
uniprot
Q9UQ08
resolver
uniprot
Q9UQ09
resolver
uniprot_entry
CE170_HUMAN
resolver
uniprot_sec
O75058
resolver
uniprot_sec
Q5SW77
resolver
uniprot_sec
Q5SW78
resolver
uniprot_sec
Q7LGA9
resolver
uniprot_sec
Q86W31
resolver
uniprot_sec
Q9UQ08
resolver
uniprot_sec
Q9UQ09
resolver
amino_acid_sequence
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSYFEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEHKKLQKVQATEKHQDQAVTSSAHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPVINEKHKDLIKDWALSSAAAVMEERKPLTTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKETSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCREETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAMIDPDGTLEALNNMGFPSAMLPSPPKQKSSPVNNHHSPGQTPTLGQPEARALHPAAVSAAAEFENAESEADFSIHFNRFNPDGEEEDVTVQE
uniprot
proteins
function
FUNCTION: Plays a role in microtubule organization (PubMed:15616186). Required for centriole subdistal appendage assembly (PubMed:28422092). {ECO:0000269|PubMed:15616186, ECO:0000269|PubMed:28422092}.
uniprot
proteins
mass_dalton
175293
uniprot
proteins
post_translational_modification
PTM: Phosphorylated; probably by PLK1. {ECO:0000269|PubMed:15616186}.
uniprot
proteins
protein_family
CEP170 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616186
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23386061
uniprot
proteins
pubmed
28422092
uniprot
proteins
pubmed
30354798
uniprot
proteins
pubmed
31789463
uniprot
proteins
pubmed
9455484
uniprot
proteins
sequence_length
1584
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:30354798, ECO:0000269|PubMed:31789463}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:15616186, ECO:0000269|PubMed:23386061, ECO:0000269|PubMed:31789463}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:15616186}. Note=Associated with the mature mother centriole. Associated with spindle microtubules during mitosis. Localizes to the distal appendage region of the centriole (PubMed:31789463). Localizes at the centriole proximal ends (PubMed:31789463). {ECO:0000269|PubMed:23386061, ECO:0000269|PubMed:31789463}.
uniprot
proteins