Evl
entrez
79115
canonical
uniprot
O08719
canonical
ensembl
ENSRNOG00000014476
resolver
ensp
ENSRNOP00000019584
resolver
ensp
ENSRNOP00000072070
resolver
ensp
ENSRNOP00000092151
resolver
ensp
ENSRNOP00000101632
resolver
ensp
ENSRNOP00000107038
resolver
ensp
ENSRNOP00000112463
resolver
enst
ENSRNOT00000113728
resolver
enst
ENSRNOT00000142269
resolver
genesymbol
Evl
resolver
genesymbol_syn
Rnb6
resolver
uniprot
A0A0G2K217
resolver
uniprot
A0A8I6AH17
resolver
uniprot
A0ABK0LMX9
resolver
uniprot_entry
A0A8I6AH17_RAT
resolver
uniprot_entry
A0ABK0LMX9_RAT
resolver
uniprot_entry
EVL_RAT
resolver
uniprot_sec
A0A0G2K217
resolver
amino_acid_sequence
MFAFEEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGPSTQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATGPILPPGHPSSAASATFSCSGPPPPPPPPVPPPPTGSTPPPPPPLPAGGAQGTNHDESSASGLAAALAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNKLLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPGSRATSQPPNSSEAGRKPWERSNSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIIDAIRQELSGISTT
uniprot
proteins
function
FUNCTION: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
45152
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PKA; phosphorylation abolishes binding to SH3 domains of ABL and SRC. {ECO:0000250}.
uniprot
proteins
protein_family
Ena/VASP family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9268706
uniprot
proteins
sequence_length
420
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P70429}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:P70429}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P70429}. Note=Targeted to the leading edge of lamellipodia and the distal tip of stress fibers through interaction with a number of proteins. In activated T-cells, localizes to the F-actin collar and the distal tip of microspikes. {ECO:0000250|UniProtKB:P70429}.
uniprot
proteins