Ppp2r2d
entrez
246255
canonical
uniprot
P56932
canonical
ensembl
ENSRNOG00000016940
resolver
ensp
ENSRNOP00000023139
resolver
enst
ENSRNOT00000023139
resolver
genesymbol
Ppp2r2d
resolver
uniprot
A0A0G2JSQ0
resolver
uniprot
Q66HR7
resolver
uniprot_entry
2ABD_RAT
resolver
uniprot_entry
A0A0G2JSQ0_RAT
resolver
uniprot_sec
Q66HR7
resolver
amino_acid_sequence
MAGAGGGGCPTGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHHVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDVTLEASRENSKPRASLKPRKVCSGGKRKKDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN
uniprot
proteins
function
FUNCTION: Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67 (By similarity). The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis (By similarity). {ECO:0000250|UniProtKB:Q7ZX64, ECO:0000250|UniProtKB:Q925E7}.
uniprot
proteins
mass_dalton
51982
uniprot
proteins
protein_family
Phosphatase 2A regulatory subunit B family
uniprot
proteins
pubmed
10556517
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10556517}.
uniprot
proteins