Igsf5
entrez
304000
canonical
uniprot
Q5VJ70
canonical
ensembl
ENSRNOG00000028216
resolver
ensembl
ENSRNOG00055016811
resolver
ensembl
ENSRNOG00060022329
resolver
ensembl
ENSRNOG00065013875
resolver
ensp
ENSRNOP00000032595
resolver
ensp
ENSRNOP00000084327
resolver
ensp
ENSRNOP00055022995
resolver
ensp
ENSRNOP00060032000
resolver
ensp
ENSRNOP00065017766
resolver
enst
ENSRNOT00000032566
resolver
enst
ENSRNOT00000100325
resolver
enst
ENSRNOT00055028556
resolver
enst
ENSRNOT00060038747
resolver
enst
ENSRNOT00065022874
resolver
genesymbol
Igsf5
resolver
genesymbol_syn
Jam4
resolver
uniprot
A0A8I5ZZA6
resolver
uniprot_entry
A0A8I5ZZA6_RAT
resolver
uniprot_entry
IGSF5_RAT
resolver
amino_acid_sequence
MEGSWRDVLAVLVILAQLTVSGSSYQIIEGPRNVTALKGSEARFNCTVTHGWKLIMWALNGIVELSLTSQKPIITSNRFTSASYNSTDSFISEMIIHNVQLNDSGPVQCSLQNSNVFGFAFLSVQVMGTLNIPSSNLIVTEGEPCNVTCYAVGWTPLPNISWELEVPVSHSSYYSFLEPGNSLRVLSVLDLTPLGNGTLTCVAEMKDLQASESLTVNLTVVQPPPDSIGGEGQALPTWAIILLAVAFSLLLILIIALIIIFCCCCVSRREKEESTYQNEIRKSANVRTGKADPETWLKSGKENYGYKSDEARAAQIASLPPKSGEVSLPEQRSSLPQQELDKHRPSPVTHPRVSFDIASPQKIRNVTIV
uniprot
proteins
function
FUNCTION: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
40281
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12940823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16118391
uniprot
proteins
pubmed
16155592
uniprot
proteins
sequence_length
369
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:12940823, ECO:0000269|PubMed:16118391}; Single-pass type I membrane protein {ECO:0000255}. Cell junction, tight junction {ECO:0000269|PubMed:12940823}. Note=In podocytes, it is mainly found in the apical plasma membrane where no junctional structure is seen. The subcellular location is altered in puromycin amino-nucleoside nephropathy (PAN). A cytoplasmic localization has been observed which may indicate the existence of variants lacking a signal sequence (PubMed:16118391). May be primarily targeted to apical membranes and subsequently recruited to tight-junctions (PubMed:12940823). {ECO:0000269|PubMed:12940823, ECO:0000269|PubMed:16118391}.
uniprot
proteins
transmembrane_region
TRANSMEM 240..260; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins