Tst
entrez
25274
canonical
uniprot
P24329
canonical
ensembl
ENSRNOG00000000186
resolver
ensp
ENSRNOP00000109235
resolver
enst
ENSRNOT00000134585
resolver
genesymbol
Tst
resolver
uniprot
A0ABK0LT25
resolver
uniprot
Q5I0D4
resolver
uniprot_entry
A0ABK0LT25_RAT
resolver
uniprot_entry
THTR_RAT
resolver
uniprot_sec
Q5I0D4
resolver
amino_acid_sequence
MVHQVLYRALVSTKWLAESIRSGKVGPSLRVLDASWYSPGTRQARKEYQERHVPGASFFDIEECRDTTSPYEMMLPSEAHFGDYVGNLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLNRSLLKTYEQVLENLQSKRFQLVDSRAQGRYLGTQPEPDAVGLDSGHIRGSVNVPFMNFLTEDGFEKSPEELRAIFQDKKVDLSQPLIATCRKGVTACHIALAAYLCGKPDVAVYDGSWSEWFRRAPPETRVSQGKSGKA
uniprot
proteins
ec_number
2.8.1.1
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of sulfur ion from thiosulfate to cyanide, although other thiol compounds, besides cyanide, can act as sulfur ion acceptors (PubMed:7608189). It also has weak mercaptopyruvate sulfurtransferase (MST) activity (PubMed:7608189). Has a pivotal role in cyanide detoxification (By similarity). Together with MRPL18, it acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (By similarity). {ECO:0000250|UniProtKB:Q16762, ECO:0000269|PubMed:7608189}.
uniprot
proteins
mass_dalton
33407
uniprot
proteins
mutagenesis
MUTAGEN 249; /note="R->G: Unaltered rhodanese activity; increased MST activity."; /evidence="ECO:0000269|PubMed:7608189"; MUTAGEN 250; /note="K->S: Decreased rhodanese activity; unaltered MST activity."; /evidence="ECO:0000269|PubMed:7608189
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2018478
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
24098488
uniprot
proteins
pubmed
7608189
uniprot
proteins
pubmed
8702895
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:8702895}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q16762}.
uniprot
proteins