Tspear
entrez
252974
canonical
uniprot
J3S6Y1
canonical
ensembl
ENSMUSG00000069581
resolver
ensp
ENSMUSP00000090020
resolver
genesymbol
Tspear
resolver
genesymbol_syn
Tnep1
resolver
uniprot
Q8BUQ8
resolver
uniprot
Q8K4Y9
resolver
uniprot_entry
TSEAR_MOUSE
resolver
uniprot_sec
Q8BUQ8
resolver
uniprot_sec
Q8K4Y9
resolver
amino_acid_sequence
MSALLMLCAVLLLLGTPSRGARPWEPCTDLRPLDILAEVVPLNGATSGIRMVQVEGVRGLQFSATEPRTTSFPASRIFSSCDFFPEEFSIIVTLRVPNLPPKKNEYLLSLLAEERDTLLLGLRYSPTQLHFLFLSEDLAGAWQTRVSFWSPGLMDSRWHTLILAVSQGSFSLTTDCGLPVDIMADVSFPPTLSVRGARFFIGSRKRTKGLFTGVIRQLVLLPGSDATPQLCPSRNARLAELSIPQVLKRLTGKPDDNEVLNYPYEADMKVTLGSRPPCTKAEGAQFWFDAAQKGLYLCAGSEWVSVLAAKTKLDYVEEHQSLHTNSETLGIEVFSIPGVGLFAAAANRKARSAIYKWTDGKFVSYQNIATHQAQSWRHFTIGKKIFLAVANFGPNERGQEFSVIYKWSPRKLKFTLYQRIATHSARDWEAFEVDGEHFLVVANHREGDNHNIDSMVYRWNPSSQLFEANQSIATSGAYDWEFFTVGPYSFLVVANTFNGTSTQVHSHLYIWLVGAFQLFQSFLTFGAADWEVFHIGERIFLAVANSHSYDVQMQAQNDSYVLSSVIYELNITAQTFVKFQDIPTCSALDWEFFSVGEDHFLVVANSFDGNTFSVNSIIYRWQGYEGFVAVHKLPTFGCRDWEAFNTTAGSYLIYSSAKEPLSRVLKLRTG
uniprot
proteins
function
FUNCTION: Plays a critical role in tooth and hair follicle morphogenesis through regulation of the Notch signaling pathway. May play a role in development or function of the auditory system. {ECO:0000250|UniProtKB:Q8WU66}.
uniprot
proteins
mass_dalton
75098
uniprot
proteins
pubmed
12217514
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22678063
uniprot
proteins
sequence_length
670
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22678063}. Cell surface {ECO:0000269|PubMed:22678063}. Cell projection, stereocilium {ECO:0000269|PubMed:22678063}. Note=Secreted protein which may bind to the cell surface via a membrane receptor. {ECO:0000269|PubMed:22678063}.
uniprot
proteins