ATP5MJ
entrez
9556
canonical
uniprot
P56378
canonical
ensembl
ENSG00000156411
resolver
ensp
ENSP00000286953
resolver
ensp
ENSP00000401770
resolver
genesymbol
ATP5MJ
resolver
genesymbol_syn
ATP5MPL
resolver
genesymbol_syn
C14orf2
resolver
genesymbol_syn
MP68
resolver
hgnc
HGNC:1188
resolver
uniprot
B2R588
resolver
uniprot
G3V5Q3
resolver
uniprot
Q86TT7
resolver
uniprot_entry
ATP68_HUMAN
resolver
uniprot_sec
B2R588
resolver
uniprot_sec
G3V5Q3
resolver
uniprot_sec
Q86TT7
resolver
amino_acid_sequence
MLQSIIKNIWIPMKPYYTKVYQEIWIGMGLMGFIVYKIRAADKRSKALKASAPAPGHH
uniprot
proteins
function
FUNCTION: Subunit j, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (PubMed:37244256). Minor subunit required to maintain the ATP synthase population in the mitochondria (PubMed:24330338). {ECO:0000250|UniProtKB:P19483, ECO:0000269|PubMed:24330338, ECO:0000269|PubMed:37244256, ECO:0000305|PubMed:37244256}.
uniprot
proteins
mass_dalton
6662
uniprot
proteins
protein_family
Small mitochondrial proteolipid family
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24330338
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
37244256
uniprot
proteins
pubmed
9653160
uniprot
proteins
sequence_length
58
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000269|PubMed:24330338}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..39; /note="Helical"; /evidence="ECO:0000269|PubMed:37244256, ECO:0007744|PDB:8H9V
uniprot
proteins