Eef1a2
entrez
24799
canonical
uniprot
P62632
canonical
ensembl
ENSRNOG00000072254
resolver
ensembl
ENSRNOG00055001118
resolver
ensembl
ENSRNOG00060001221
resolver
ensembl
ENSRNOG00065013809
resolver
ensp
ENSRNOP00000016947
resolver
ensp
ENSRNOP00000090613
resolver
ensp
ENSRNOP00055001461
resolver
ensp
ENSRNOP00060000952
resolver
ensp
ENSRNOP00065017613
resolver
enst
ENSRNOT00000016947
resolver
enst
ENSRNOT00055001861
resolver
enst
ENSRNOT00060001737
resolver
enst
ENSRNOT00065022716
resolver
genesymbol
Eef1a2
resolver
genesymbol_syn
Eef1al
resolver
genesymbol_syn
Stn
resolver
genesymbol_syn
Stnl
resolver
uniprot
P27706
resolver
uniprot_entry
EF1A2_RAT
resolver
uniprot_sec
P27706
resolver
amino_acid_sequence
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK
uniprot
proteins
ec_number
3.6.5.-
uniprot
proteins
function
FUNCTION: Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis. Base pairing between the mRNA codon and the aa-tRNA anticodon promotes GTP hydrolysis, releasing the aa-tRNA from EEF1A1 and allowing its accommodation into the ribosome (By similarity). The growing protein chain is subsequently transferred from the P-site peptidyl tRNA to the A-site aa-tRNA, extending it by one amino acid through ribosome-catalyzed peptide bond formation (By similarity). {ECO:0000250|UniProtKB:P68104, ECO:0000250|UniProtKB:Q71V39}.
uniprot
proteins
mass_dalton
50454
uniprot
proteins
post_translational_modification
PTM: Trimethylated at Lys-165 by EEF1AKMT3. Mono-, di-, and trimethylated at Lys-36 by EEF1AKMT4; trimethylated form is predominant. Methylation by EEF1AKMT4 contributes to the fine-tuning of translation rates for a subset of tRNAs. Trimethylated at the N-terminus and dimethylated at Lys-55 by METTL13. {ECO:0000250|UniProtKB:Q05639}.
uniprot
proteins
protein_family
Classic translation factor GTPase family
uniprot
proteins
protein_family
EF-Tu/EF-1A subfamily
uniprot
proteins
protein_family
TRAFAC class translation factor GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1709933
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
463
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q05639}.
uniprot
proteins