DDX19B
entrez
11269
canonical
uniprot
Q9UMR2
canonical
ensembl
ENSG00000157349
resolver
ensp
ENSP00000288071
resolver
ensp
ENSP00000348271
resolver
ensp
ENSP00000377267
resolver
ensp
ENSP00000392639
resolver
ensp
ENSP00000455813
resolver
ensp
ENSP00000456574
resolver
ensp
ENSP00000456757
resolver
enst
ENST00000563206
resolver
genesymbol
DDX19B
resolver
genesymbol_syn
DBP5
resolver
genesymbol_syn
DDX19
resolver
genesymbol_syn
TDBP
resolver
hgnc
HGNC:2742
resolver
uniprot
A0A0U4B4U6
resolver
uniprot
B3KNE9
resolver
uniprot
B4DXS6
resolver
uniprot
E7EMK4
resolver
uniprot
H3BQK0
resolver
uniprot
Q6FIB7
resolver
uniprot
Q6IAE0
resolver
uniprot
Q96KE7
resolver
uniprot
Q9H0U0
resolver
uniprot_entry
A0A0U4B4U6_HUMAN
resolver
uniprot_entry
DD19B_HUMAN
resolver
uniprot_entry
H3BQK0_HUMAN
resolver
uniprot_sec
B3KNE9
resolver
uniprot_sec
B4DXS6
resolver
uniprot_sec
E7EMK4
resolver
uniprot_sec
Q6FIB7
resolver
uniprot_sec
Q6IAE0
resolver
uniprot_sec
Q96KE7
resolver
uniprot_sec
Q9H0U0
resolver
amino_acid_sequence
MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: ATP-dependent RNA helicase involved in mRNA export from the nucleus (PubMed:10428971). Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (PubMed:10428971). {ECO:0000269|PubMed:10428971}.
uniprot
proteins
mass_dalton
53927
uniprot
proteins
mutagenesis
MUTAGEN 223; /note="D->R: Impairs interaction with NUP214 and RNA."; /evidence="ECO:0000269|PubMed:19219046"; MUTAGEN 243; /note="E->Q: Loss of activity."; /evidence="ECO:0000269|PubMed:10428971"; MUTAGEN 258; /note="I->A: Impairs interaction with NUP214."; /evidence="ECO:0000269|PubMed:19219046"; MUTAGEN 259; /note="R->D: Impairs interaction with NUP214."; /evidence="ECO:0000269|PubMed:19219046"; MUTAGEN 262; /note="R->A: Impairs interaction with NUP214."; /evidence="ECO:0000269|PubMed:19219046
uniprot
proteins
protein_family
DDX19/DBP5 subfamily
uniprot
proteins
protein_family
DEAD box helicase family
uniprot
proteins
pubmed
10428971
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
12219940
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
19208808
uniprot
proteins
pubmed
19219046
uniprot
proteins
pubmed
19244245
uniprot
proteins
pubmed
22223895
uniprot
proteins
sequence_length
479
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10428971}. Nucleus, nucleoplasm {ECO:0000269|PubMed:10428971}. Note=Associates with the nuclear pore complex cytoplasmic fibrils. {ECO:0000269|PubMed:10428971}.
uniprot
proteins