Pomk
entrez
74653
canonical
uniprot
Q3TUA9
canonical
ensembl
ENSMUSG00000037251
resolver
ensp
ENSMUSP00000053802
resolver
enst
ENSMUST00000061850
resolver
genesymbol
Pomk
resolver
genesymbol_syn
Sgk196
resolver
uniprot
Q3TBZ0
resolver
uniprot
Q8BZ83
resolver
uniprot
Q8R2S2
resolver
uniprot
Q9D5G4
resolver
uniprot_entry
SG196_MOUSE
resolver
uniprot_sec
Q3TBZ0
resolver
uniprot_sec
Q8BZ83
resolver
uniprot_sec
Q8R2S2
resolver
uniprot_sec
Q9D5G4
resolver
amino_acid_sequence
MGQQHGTRNGLTHRELPRGVGLLLAMALMNVALYLCLDQLFISPGRSTADSRRCPPGYFRMGRMRNCSRWLSCEELRTEVRQLKRVGEGAVKRVFLSEWKEHKVALSRLTRLEMKEDFLHGLQMLKSLQSEHVVTLVGYCEEDGTILTEYHPLGSLSNLEETLNLSKYQDVNTWQHRLQLAMEYVSIINYLHHSPLGTRVMCDSNDLPKTLSQYLLTSNFSIVANDLDALPLVDHDSGVLIKCGHRELHGDFVAPEQLWPYGEDTPFQDDLMPSYNEKVDIWKIPDVSSFLLGHVEGSDMVRFHLFDIHKACKSQIPAERPTAQNVLDAYQRVFHSLRDTVMSQTKEML
uniprot
proteins
ec_number
2.7.1.183
uniprot
proteins
function
FUNCTION: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
39969
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
STKL subfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21746835
uniprot
proteins
sequence_length
349
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..42; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins