AP1M2
entrez
10053
canonical
uniprot
Q9Y6Q5
canonical
ensembl
ENSG00000129354
resolver
ensp
ENSP00000250244
resolver
ensp
ENSP00000465685
resolver
genesymbol
AP1M2
resolver
hgnc
HGNC:558
resolver
uniprot
B2RDV5
resolver
uniprot
Q53GI5
resolver
uniprot
Q9BSI8
resolver
uniprot_entry
AP1M2_HUMAN
resolver
uniprot_entry
Q53GI5_HUMAN
resolver
uniprot_sec
B2RDV5
resolver
uniprot_sec
Q9BSI8
resolver
amino_acid_sequence
MSASAVFILDVKGKPLISRNYKGDVAMSKIEHFMPLLVQREEEGALAPLLSHGQVHFLWIKHSNLYLVATTSKNANASLVYSFLYKTIEVFCEYFKELEEESIRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQQSNKLETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTGRSKNKSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKSFPGGKEYLMRAHFGLPSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEKSGYQALPWVRYITQSGDYQLRTS
uniprot
proteins
function
FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
uniprot
proteins
mass_dalton
48108
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. {ECO:0000250}.
uniprot
proteins
protein_family
Adaptor complexes medium subunit family
uniprot
proteins
pubmed
10338135
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
uniprot
proteins