RMI1
entrez
80010
canonical
uniprot
Q9H9A7
canonical
ensembl
ENSG00000178966
resolver
ensp
ENSP00000317039
resolver
ensp
ENSP00000402433
resolver
ensp
ENSP00000561360
resolver
ensp
ENSP00000561361
resolver
ensp
ENSP00000561362
resolver
ensp
ENSP00000561363
resolver
ensp
ENSP00000561364
resolver
ensp
ENSP00000585882
resolver
ensp
ENSP00000585883
resolver
ensp
ENSP00000585884
resolver
ensp
ENSP00000585885
resolver
ensp
ENSP00000585886
resolver
ensp
ENSP00000585887
resolver
ensp
ENSP00000585888
resolver
ensp
ENSP00000585889
resolver
ensp
ENSP00000585890
resolver
ensp
ENSP00000585891
resolver
ensp
ENSP00000585892
resolver
ensp
ENSP00000627735
resolver
enst
ENST00000325875
resolver
enst
ENST00000445877
resolver
enst
ENST00000891301
resolver
enst
ENST00000891302
resolver
enst
ENST00000891303
resolver
enst
ENST00000891304
resolver
enst
ENST00000891305
resolver
enst
ENST00000915823
resolver
enst
ENST00000915824
resolver
enst
ENST00000915825
resolver
enst
ENST00000915826
resolver
enst
ENST00000915827
resolver
enst
ENST00000915828
resolver
enst
ENST00000915829
resolver
enst
ENST00000915830
resolver
enst
ENST00000915831
resolver
enst
ENST00000915832
resolver
enst
ENST00000915833
resolver
enst
ENST00000957676
resolver
genesymbol
RMI1
resolver
genesymbol_syn
C9orf76
resolver
hgnc
HGNC:25764
resolver
uniprot
Q05BX1
resolver
uniprot
Q05CW3
resolver
uniprot
Q5SQG8
resolver
uniprot
Q5SQG9
resolver
uniprot
Q6P1Q4
resolver
uniprot
Q6PI89
resolver
uniprot
Q7Z6L6
resolver
uniprot_entry
RMI1_HUMAN
resolver
uniprot_sec
Q05BX1
resolver
uniprot_sec
Q05CW3
resolver
uniprot_sec
Q5SQG8
resolver
uniprot_sec
Q5SQG9
resolver
uniprot_sec
Q6P1Q4
resolver
uniprot_sec
Q6PI89
resolver
uniprot_sec
Q7Z6L6
resolver
amino_acid_sequence
MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTDLRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEAQVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVLLLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPALGPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPSNLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTNNFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKNLETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRNSQISNENDCNLQSCSLRSSENSINLSIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAYLDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSLSKAMVLALQDVNMEHLENLKKRLNK
uniprot
proteins
function
FUNCTION: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability. {ECO:0000269|PubMed:15775963, ECO:0000269|PubMed:16537486, ECO:0000269|PubMed:16595695}.
uniprot
proteins
mass_dalton
70144
uniprot
proteins
protein_family
RMI1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15775963
uniprot
proteins
pubmed
16537486
uniprot
proteins
pubmed
16595695
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18923082
uniprot
proteins
pubmed
18923083
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23509288
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
625
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15775963}. Note=Forms foci in response to DNA damage.
uniprot
proteins