Nubp2
entrez
287125
canonical
uniprot
Q68FS1
canonical
ensembl
ENSRNOG00000015090
resolver
ensembl
ENSRNOG00055023881
resolver
ensembl
ENSRNOG00060007471
resolver
ensembl
ENSRNOG00065009307
resolver
ensp
ENSRNOP00000083949
resolver
ensp
ENSRNOP00055033413
resolver
ensp
ENSRNOP00060009401
resolver
ensp
ENSRNOP00065011134
resolver
enst
ENSRNOT00055041083
resolver
enst
ENSRNOT00060012431
resolver
enst
ENSRNOT00065014908
resolver
genesymbol
Nubp2
resolver
uniprot_entry
NUBP2_RAT
resolver
amino_acid_sequence
MEAAAEPGNLAGVRHIILVLSGKGGVGKSTISTELALALRHQGKKVGILDVDLCGPSIPHMLHAQGKAVHQCDSGWVPVFVDQEQSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGELDYLVVDTPPGTSDEHMATVEALRPYKPLGALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFACPHCAECTNVFSSGGGEELARLAGVPFLGSVPLDPQLTRSLEEGRDFIQEFPKSTAYSALTSIAHKVLHQMPALCS
uniprot
proteins
function
FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure. {ECO:0000250|UniProtKB:Q9R061, ECO:0000255|HAMAP-Rule:MF_03039}.
uniprot
proteins
mass_dalton
28926
uniprot
proteins
protein_family
Mrp/NBP35 ATP-binding proteins family
uniprot
proteins
protein_family
NUBP2/CFD1 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|HAMAP-Rule:MF_03039}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255|HAMAP-Rule:MF_03039}. Cytoplasm {ECO:0000250|UniProtKB:Q9R061}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9R061}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9R061}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q9R061}. Note=Enriched at the centrosomes during mitosis. Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis (By similarity). Localized at centrioles and in the nucleus at interphase (By similarity). Colocalizes with nubp-1 at prometaphase (By similarity). {ECO:0000250|UniProtKB:Q9R061, ECO:0000255|HAMAP-Rule:MF_03039}.
uniprot
proteins