Q9EPI1
uniprot
Q9EPI1
canonical
amino_acid_sequence
YFSHRPKEKVRTDSNNENSVPKDFENVDNSNFAPRTQKQKHQPELAKKPLSRQKERLQRKLGAQDKGQGQSVLGKGPKEVLPPREKAPGNSSQGKDLSRHSHSRKSGGGGSPETKSDQVPKCDISGKEAISALTRAKSKHCRQEIAETYCRHKLGLLMPEKVARFCPLEGKANKNVQWDEDAVEYMPPNPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVDKRSNYLHRQVLQFSRQYDNVRVTSWRMATIWGGASLLSTYLQSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARFIRKQDLDRLFLECDTHMWRLGDRRIPEGIAVDGGSDWFLLNRKFVEYVAFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEAIVNQEIIGQLDSYLYGNYPAGTPGLRSYWENVYDEPDGIQSLSDVALTMYHSFIRLGLRRAESSLHTDGENSCRYYPMGHPASVHLYFLADRFQGFLIKHHVTNLAVSKLETLETWMMPKKVFKVASPPSDFGRLQFSEVGTDWDAKERLFRNFGGLLGPMDEPVGMQKWGKGPNVTVTVIWVDPVNVIAATYDILIESTAEFTHYKPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNKQPIKPEEALKLHNGPPRSAYMEQSFQSLNPVLSLHINPAQVEQARKNAAFTGTALEAWLVGGTWTAMDVCATGPTACPVMQTCSQTAWSSFSPDPKSELGAVKPDGRLR
uniprot
proteins
ec_number
2.4.2.26
uniprot
proteins
function
FUNCTION: Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones. {ECO:0000250|UniProtKB:Q811B1}.
uniprot
proteins
mass_dalton
93859
uniprot
proteins
pathway_participation
PATHWAY: Glycan metabolism; chondroitin sulfate biosynthesis. {ECO:0000250|UniProtKB:Q86Y38}.; PATHWAY: Glycan metabolism; heparan sulfate biosynthesis. {ECO:0000250|UniProtKB:Q86Y38}.
uniprot
proteins
post_translational_modification
PTM: Contains 7 disulfide bonds. {ECO:0000250|UniProtKB:Q86Y38}.; PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q86Y38}.
uniprot
proteins
protein_family
Glycosyltransferase 14 family
uniprot
proteins
protein_family
XylT subfamily
uniprot
proteins
pubmed
11099377
uniprot
proteins
sequence_length
821
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q86Y38}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins