SLC39A13
entrez
91252
canonical
uniprot
Q96H72
canonical
ensembl
ENSG00000165915
resolver
ensp
ENSP00000346956
resolver
ensp
ENSP00000354689
resolver
ensp
ENSP00000434290
resolver
ensp
ENSP00000434684
resolver
ensp
ENSP00000539800
resolver
ensp
ENSP00000581922
resolver
ensp
ENSP00000581925
resolver
ensp
ENSP00000638952
resolver
ensp
ENSP00000662684
resolver
ensp
ENSP00000680071
resolver
ensp
ENSP00000680080
resolver
ensp
ENSP00000793833
resolver
enst
ENST00000533076
resolver
genesymbol
SLC39A13
resolver
genesymbol_syn
ZIP13
resolver
hgnc
HGNC:20859
resolver
uniprot
D3DQR6
resolver
uniprot
D3DQR7
resolver
uniprot
E9PLY1
resolver
uniprot
E9PQV3
resolver
uniprot
G3V1B2
resolver
uniprot
Q659D9
resolver
uniprot
Q8N7C9
resolver
uniprot
Q8WV10
resolver
uniprot_entry
G3V1B2_HUMAN
resolver
uniprot_entry
S39AD_HUMAN
resolver
uniprot_sec
D3DQR6
resolver
uniprot_sec
D3DQR7
resolver
uniprot_sec
E9PLY1
resolver
uniprot_sec
E9PQV3
resolver
uniprot_sec
Q659D9
resolver
uniprot_sec
Q8N7C9
resolver
uniprot_sec
Q8WV10
resolver
amino_acid_sequence
MPGCPCPGCGMAGPRLLFLTALALELLERAGGSQPALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFSLFVD
uniprot
proteins
disease_involvement
DISEASE: Ehlers-Danlos syndrome, spondylodysplastic type, 3 (EDSSPD3) [MIM:612350]: A form of Ehlers-Danlos syndrome, a group of connective tissue disorders characterized by skin hyperextensibility, articular hypermobility, and tissue fragility. EDSSPD3 is an autosomal recessive form characterized by a generalized skeletal dysplasia involving mainly the spine and striking clinical abnormalities of the hands, in addition to classic features of Ehlers-Danlos syndrome. Clinical features include postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar muscles, and tapering fingers. Radiologic features include mild to moderate platyspondyly, mild to moderate osteopenia of the spine, small ileum, flat proximal femoral epiphyses, short, wide femoral necks, and broad metaphyses (elbows, knees, wrists, and interphalangeal joints). {ECO:0000269|PubMed:18513683, ECO:0000269|PubMed:18985159}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Functions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol (PubMed:21917916, PubMed:23213233). May regulate beige adipocyte differentiation (By similarity). {ECO:0000250|UniProtKB:Q8BZH0, ECO:0000269|PubMed:21917916, ECO:0000269|PubMed:23213233}.
uniprot
proteins
mass_dalton
39011
uniprot
proteins
protein_family
ZIP transporter (TC 2.A.5) family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18513683
uniprot
proteins
pubmed
18985159
uniprot
proteins
pubmed
21917916
uniprot
proteins
pubmed
23213233
uniprot
proteins
pubmed
31412620
uniprot
proteins
sequence_length
371
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:21917916, ECO:0000269|PubMed:31412620}; Multi-pass membrane protein {ECO:0000269|PubMed:21917916}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:23213233}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:31412620}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 69..89; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 109..129; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 150..170; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 236..256; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 279..299; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 317..337; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 350..370; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins