Arfgap1
entrez
228998
canonical
uniprot
Q9EPJ9
canonical
ensembl
ENSMUSG00000027575
resolver
ensp
ENSMUSP00000029092
resolver
ensp
ENSMUSP00000104487
resolver
ensp
ENSMUSP00000104488
resolver
ensp
ENSMUSP00000104489
resolver
ensp
ENSMUSP00000104490
resolver
ensp
ENSMUSP00000138843
resolver
ensp
ENSMUSP00000139222
resolver
ensp
ENSMUSP00000163214
resolver
ensp
ENSMUSP00000163216
resolver
ensp
ENSMUSP00000163217
resolver
ensp
ENSMUSP00000163238
resolver
ensp
ENSMUSP00000163251
resolver
ensp
ENSMUSP00000163252
resolver
ensp
ENSMUSP00000163253
resolver
ensp
ENSMUSP00000330326
resolver
ensp
ENSMUSP00000330327
resolver
enst
ENSMUST00000108861
resolver
enst
ENSMUST00000108862
resolver
enst
ENSMUST00000184394
resolver
enst
ENSMUST00000185115
resolver
genesymbol
Arfgap1
resolver
genesymbol_syn
Arf1gap
resolver
uniprot
A8WIR9
resolver
uniprot
A8WIS1
resolver
uniprot
F7DD68
resolver
uniprot
Q3TGS9
resolver
uniprot
Q3TI52
resolver
uniprot
Q6PB94
resolver
uniprot
Q8BMM6
resolver
uniprot
Q8BMQ7
resolver
uniprot
V9GWV1
resolver
uniprot
V9GXM1
resolver
uniprot_entry
ARFG1_MOUSE
resolver
uniprot_entry
F7DD68_MOUSE
resolver
uniprot_entry
Q3TGS9_MOUSE
resolver
uniprot_entry
Q6PB94_MOUSE
resolver
uniprot_entry
V9GWV1_MOUSE
resolver
uniprot_entry
V9GXM1_MOUSE
resolver
uniprot_sec
A8WIR9
resolver
uniprot_sec
A8WIS1
resolver
uniprot_sec
Q3TI52
resolver
uniprot_sec
Q8BMM6
resolver
uniprot_sec
Q8BMQ7
resolver
amino_acid_sequence
MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLETQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRASGQPQSAAASGDKAFEDWLNDDLGSYQGAQENRYVGFGNTVPPQKREDDFLNNAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEDSSDRPLEGHSYQNSSGDNSQNSNIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDVWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTADEGWDNQNW
uniprot
proteins
function
FUNCTION: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine. {ECO:0000250|UniProtKB:Q62848}.
uniprot
proteins
mass_dalton
45288
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
414
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q62848}. Cytoplasm {ECO:0000250|UniProtKB:Q62848}. Note=Associates with the Golgi complex. {ECO:0000250|UniProtKB:Q62848}.
uniprot
proteins