Sertm2
entrez
319764
canonical
uniprot
A0A1B0GSN8
canonical
ensembl
ENSMUSG00000085139
resolver
ensp
ENSMUSP00000148011
resolver
enst
ENSMUST00000135687
resolver
genesymbol
Sertm2
resolver
uniprot_entry
SRTM2_MOUSE
resolver
amino_acid_sequence
MTEVLFKYHGNLTGRAHFPTLATEADTTSDKYSNLYMYVGLFLSLLAILLILLFTMLLRLKHVISPITESTESVPQFTDVEMQSRIPTP
uniprot
proteins
function
FUNCTION: Promotes GDNF-mediated spinal cord motor neuron subtype specification, ensuring the maintenance of ETV4-expressing motor neurons (PubMed:40108406). Affects the resting membrane potential and excitability of motor neurons (PubMed:40108405). {ECO:0000269|PubMed:40108405, ECO:0000269|PubMed:40108406}.
uniprot
proteins
mass_dalton
10093
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:40108406}.
uniprot
proteins
protein_family
SERTM family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
40108405
uniprot
proteins
pubmed
40108406
uniprot
proteins
sequence_length
89
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:40108405, ECO:0000269|PubMed:40108406}. Cell membrane {ECO:0000269|PubMed:40108405, ECO:0000269|PubMed:40108406}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 38..58; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins