RNF207
entrez
388591
canonical
uniprot
Q6ZRF8
canonical
ensembl
ENSG00000158286
resolver
ensp
ENSP00000367173
resolver
ensp
ENSP00000552159
resolver
genesymbol
RNF207
resolver
genesymbol_syn
C1orf188
resolver
hgnc
HGNC:32947
resolver
uniprot
A2VCM8
resolver
uniprot
B4DFR6
resolver
uniprot
Q5TGS6
resolver
uniprot
Q6ZS63
resolver
uniprot
Q96MP2
resolver
uniprot_entry
RN207_HUMAN
resolver
uniprot_sec
A2VCM8
resolver
uniprot_sec
B4DFR6
resolver
uniprot_sec
Q5TGS6
resolver
uniprot_sec
Q6ZS63
resolver
uniprot_sec
Q96MP2
resolver
amino_acid_sequence
MSGAIFGPLEGPSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCGQPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCLEPLLLLGPRRVAAAASGANTLAGGLGPKALTGPHCPSPVGKMSGSPVQKPTLHRSISTKVLLAEGENTPFAEHCRHYEDSYRHLQAEMQSLKDQVQELHRDLTKHHSLIKAEIMGDVLHKSLQLDVQIASEHASLEGMRVVFQEIWEEAYQRVANEQEIYEAQLHDLLQLRQENAYLTTITKQITPYVRSIAKVKERLEPRFQAPVDEQSESLQNTHDDSRNNAASARNNPGSVPEKREKTSEPKGNSWAPNGLSEEPLLKNMDHHRSKQKNGGDVPTWREHPT
uniprot
proteins
function
FUNCTION: Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner. {ECO:0000269|PubMed:25281747}.
uniprot
proteins
mass_dalton
70861
uniprot
proteins
mutagenesis
MUTAGEN 25; /note="C->R: Loss of KCNH2 up-regulation."; /evidence="ECO:0000269|PubMed:25281747
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
19305408
uniprot
proteins
pubmed
19305409
uniprot
proteins
pubmed
25281747
uniprot
proteins
sequence_length
634
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:25281747}. Note=Probably located in the endoplasmic reticulum and/or possibly the cis-Golgi apparatus. {ECO:0000269|PubMed:25281747}.
uniprot
proteins