Adm
entrez
25026
canonical
uniprot
P43145
canonical
ensembl
ENSRNOG00055025720
resolver
ensembl
ENSRNOG00060020499
resolver
ensembl
ENSRNOG00065029586
resolver
ensp
ENSRNOP00055036292
resolver
ensp
ENSRNOP00060029198
resolver
ensp
ENSRNOP00065042041
resolver
enst
ENSRNOT00055044376
resolver
enst
ENSRNOT00060035522
resolver
enst
ENSRNOT00065051097
resolver
genesymbol
Adm
resolver
uniprot_entry
ADML_RAT
resolver
amino_acid_sequence
MKLVSIALMLLGSLAVLGADTARLDTSSQFRKKWNKWALSRGKRELQASSSYPTGLVDEKTVPTQTLGLQDKQSTSSTPQASTQSTAHIRVKRYRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGYGRRRRRSLPEVLRARTVESSQEQTHSAPASPAHQDISRVSRL
uniprot
proteins
function
FUNCTION: Adrenomedullin/ADM and proadrenomedullin N-20 terminal peptide/PAMP are peptide hormones that act as potent hypotensive and vasodilatator agents (PubMed:7690563). Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis (By similarity). {ECO:0000250|UniProtKB:P35318, ECO:0000269|PubMed:7690563}.; FUNCTION: [Adrenomedullin]: ADM function is mediated by the CALCRL-RAMP2 and CALCRL-RAMP3 receptor complexes with ADM showing the highest potency for the CALCRL-RAMP2 complex. {ECO:0000250|UniProtKB:P35318}.; FUNCTION: [Proadrenomedullin N-20 terminal peptide]: Peptide hormone that act as potent hypotensive and vasodilatator agents by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. Acts as a ligand for Mrgprb2 receptor in mast cells. {ECO:0000250|UniProtKB:P35318}.; FUNCTION: [Proadrenomedullin 9-20 terminal peptide]: Peptide hormone that act as potent hypotensive and vasodilatator agents by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. Acts as a ligand for Mrgprb2 receptor in mast cells. {ECO:0000250|UniProtKB:P35318}.
uniprot
proteins
mass_dalton
20636
uniprot
proteins
protein_family
Adrenomedullin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
26479776
uniprot
proteins
pubmed
7690563
uniprot
proteins
pubmed
8524787
uniprot
proteins
sequence_length
185
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P35318}.
uniprot
proteins