Grid2ip
entrez
170935
canonical
uniprot
Q0QWG9
canonical
ensembl
ENSMUSG00000010825
resolver
ensp
ENSMUSP00000010969
resolver
ensp
ENSMUSP00000106361
resolver
ensp
ENSMUSP00000113443
resolver
genesymbol
Grid2ip
resolver
uniprot
Q6DID0
resolver
uniprot
Q9ESJ5
resolver
uniprot_entry
GRD2I_MOUSE
resolver
uniprot_sec
Q6DID0
resolver
uniprot_sec
Q9ESJ5
resolver
amino_acid_sequence
MPATNQGWPEDFGFQLGGSGPCFVIEVAEGSSAHAGGLRPGDQILEVEGLAVGGLSRERIVRLARRCPRVPPSLGVLPGPEGGPTALTAAWLTRRFGRSLPLSRELLRLAGGPRPDAVHRERRRKAQEFSCQVDDILGDRLTAKEQVFTALKQFAAEQRVDELVWTLTLVLPSEAQGPVLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKATSLLGGRTGPGGPRRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPAENASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGPVPFASDSDSLDSPTRASALTSLQWVADILPSSIRVQGRTFSQQLDHLLTPPERYGVCRALERFFQHRNIDTLIVDVYPVLDTPAKQVLWQFLYQLLTYEEQELCQEKIACFLGYTAMTEPESSLDLEPESTPEPTPEPQPRSSLRASSMCRRSLRSQGLETSLSCGPGDCPEMPLPLIPGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKIGTMSKSRASPPVPSLVGTSGPRTLSGVSWPSDRLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGLGSIHADSPPSPDPIRPPSRRKLFAFSRPVRSRDTDRFLDALSEQLGPRLSIVDDFLTPENDYEEMSFHDDQGSFVTNERSSASECVSSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDPKPSSRTSDGPRGPPQSLTKPLTQINHPVPPPPPPPLPPPVPCAPPMLSRGVGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPPKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTGDLADLHDTVSEIQVACQSMAPSSEDRFAVVMASFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMSKFERALSDLQAGDGPRSSGMVSPLAW
uniprot
proteins
function
FUNCTION: Postsynaptic scaffolding protein at the Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various signaling molecules.
uniprot
proteins
mass_dalton
132021
uniprot
proteins
post_translational_modification
PTM: Isoform 2 is palmitoylated. Palmitoylation of isoform 2 is necessary for the enhanced cell surface expression of GRID2, and is also responsible for the accumulation of isoform 2 within dendritic spines. Isoform 1 and isoform 2 are differentially localized, probably modulating GRID2 signaling in neurons.
uniprot
proteins
pubmed
11826110
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16168524
uniprot
proteins
pubmed
16835239
uniprot
proteins
pubmed
17027646
uniprot
proteins
pubmed
17425562
uniprot
proteins
pubmed
17496809
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1203
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 2]: Postsynaptic cell membrane. Cell projection, dendritic spine. Note=Localized to the postsynaptic junction site of the parallel fiber-Purkinje cell synapse. Highly present in the dendritic spines.; SUBCELLULAR LOCATION: [Isoform 3]: Synapse. Cell projection, dendritic spine. Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Note=Localized at the dendritic spines, but also in dendritic shafts apart fron spines.
uniprot
proteins