Cdc37
entrez
114562
canonical
uniprot
Q63692
canonical
ensembl
ENSRNOG00000033426
resolver
ensp
ENSRNOP00000076743
resolver
genesymbol
Cdc37
resolver
uniprot
Q8CH95
resolver
uniprot_entry
CDC37_RAT
resolver
uniprot_sec
Q8CH95
resolver
amino_acid_sequence
MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGGQVELERLRAEAQQLRKEERSWEQKLEDMRKKEKNMPWNVDTLSKDGFSKSMVNTKPEKAEEDSEEAREQKHKTFVEKYEKQIKHFGMLHRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTMVMQFILELAKSLKVDPRACFRQFFTKIKTADQQYMEGFKYELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKSGEAKEGEEAGPGDPLLEAVPKAGNEKDISA
uniprot
proteins
function
FUNCTION: Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity. {ECO:0000250|UniProtKB:Q16543}.
uniprot
proteins
mass_dalton
44510
uniprot
proteins
post_translational_modification
PTM: Constitutively sumoylated by UBE2I. {ECO:0000250|UniProtKB:Q16543}.
uniprot
proteins
protein_family
CDC37 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8534368
uniprot
proteins
pubmed
8945638
uniprot
proteins
sequence_length
379
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q16543}.
uniprot
proteins