Bid
entrez
64625
canonical
uniprot
Q9JLT6
canonical
ensembl
ENSRNOG00000012439
resolver
ensembl
ENSRNOG00055010823
resolver
ensembl
ENSRNOG00060025803
resolver
ensembl
ENSRNOG00065029226
resolver
ensp
ENSRNOP00000016776
resolver
ensp
ENSRNOP00055014729
resolver
ensp
ENSRNOP00060037043
resolver
ensp
ENSRNOP00065041510
resolver
enst
ENSRNOT00000016776
resolver
enst
ENSRNOT00055018321
resolver
enst
ENSRNOT00060044691
resolver
enst
ENSRNOT00065050513
resolver
genesymbol
Bid
resolver
uniprot
A8ASI9
resolver
uniprot
Q9JK60
resolver
uniprot_entry
A8ASI9_RAT
resolver
uniprot_entry
BID_RAT
resolver
uniprot_sec
Q9JK60
resolver
amino_acid_sequence
MDSEVSNGSGLGAEHITNLLVFGFLRNNDRDFHQELEVLGQELPVQVYLEGDREDELQTDGSRASRSFYHGRIEPDSESQDEVIHNIARHLAQAGDELDHSIQPTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVKTSFPRDMENDKAMLIMTMLLAKKVASHAPSLLRDVFRTTVNFINQNLFSYVRDLVRNEMD
uniprot
proteins
function
FUNCTION: Induces caspases and apoptosis. Counters the protective effect of BCL2. {ECO:0000250|UniProtKB:P70444}.; FUNCTION: [BH3-interacting domain death agonist p15]: Induces caspase activation and apoptosis (By similarity). Translocates to mitochondria following cleavage and disrupts the outer mitochondrial membrane leading to the release of cytochrome c (By similarity). {ECO:0000250|UniProtKB:P55957}.
uniprot
proteins
mass_dalton
22249
uniprot
proteins
post_translational_modification
PTM: [BH3-interacting domain death agonist]: TNF induces caspase-mediated cleavage into a major p15 and minor p13 and p11 products. Cleaved by CASP6 or CASP8 into a major p15 and minor p13 products, leading to release of cytochrome c. Also cleaved by GZMK to generate p15. {ECO:0000250|UniProtKB:P55957}.; PTM: [BH3-interacting domain death agonist p15]: Ubiquitinated by ITCH; ubiquitination results in proteasome-dependent degradation. {ECO:0000250|UniProtKB:P70444}.
uniprot
proteins
pubmed
12787069
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
196
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P70444}. Mitochondrion membrane {ECO:0000250|UniProtKB:P70444}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:P55957}. Note=When uncleaved, it is predominantly cytoplasmic (By similarity). {ECO:0000250|UniProtKB:P70444}.; SUBCELLULAR LOCATION: [BH3-interacting domain death agonist p15]: Mitochondrion membrane {ECO:0000250|UniProtKB:P55957}. Note=Translocates to mitochondria following cleavage. {ECO:0000250|UniProtKB:P55957}.; SUBCELLULAR LOCATION: [BH3-interacting domain death agonist p13]: Mitochondrion membrane {ECO:0000250|UniProtKB:P70444}. Note=Associated with the mitochondrial membrane. {ECO:0000250|UniProtKB:P70444}.
uniprot
proteins