Slc45a4
entrez
106068
canonical
uniprot
Q0P5V9
canonical
ensembl
ENSMUSG00000079020
resolver
ensp
ENSMUSP00000075577
resolver
ensp
ENSMUSP00000115827
resolver
ensp
ENSMUSP00000121775
resolver
ensp
ENSMUSP00000283107
resolver
ensp
ENSMUSP00000283113
resolver
ensp
ENSMUSP00000283116
resolver
genesymbol
Slc45a4
resolver
genesymbol_syn
Kiaa1126
resolver
uniprot
Q3TCG5
resolver
uniprot
Q3V0B8
resolver
uniprot
Q69ZR4
resolver
uniprot
Q6PDG3
resolver
uniprot_entry
S45A4_MOUSE
resolver
uniprot_sec
Q3TCG5
resolver
uniprot_sec
Q3V0B8
resolver
uniprot_sec
Q69ZR4
resolver
uniprot_sec
Q6PDG3
resolver
amino_acid_sequence
MKMAPQNADSESMQVQELPVPLPDPQKPRDPEAETQEETTSEGSIDRIPTRLWVMHGAVMFGREFCYAMETALVTPILLQIGLPEKYYSLTWFLSPVLGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLIGVALFLNGSAIGLALGDVPSRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALNIHAFSAGLGGAIGYVLGGLDWTQTFLGDWFQTQNQVLFFFAAVIFSVSVALHLFSIEEEQYSPQQDRGPEDPTLPGTSVQPGAPAPASRLSSLGGGMQDGSPPFPDEVQSEHELSLDYLDVDIVRSKSDSVLHMADATLDMEPQLLFLHDIEPSIFQDASYPSTPQSTSQELLRAKLPRLSTFLRESTKEDDTLLDNHLNEAKVPNGRGSPPINSLSRSKVDLKPSVTSGSMRRRRHMFHRQASSTFSYYGKIGSHCYRYRRANAVVLIKPSRSMSDLYDLQQRQRSRHRNQSGATASSGDTESEEGETETTVRLLWLSMLKMPKELMWLCLCHLLTWFSVIAEAVFYTDFMGQVIFKGNPQAPSNSTKWHAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSIRIIYMLGTLGFSVGTAVMAMFPNVYVAMVTISTMGVVSMSISYCPYALLGHYHDIKEYVHHSPGNSKRGFGIDCAILSCQVYISQILVASALGGVVDAVNSIVVIPIVASVGSFLGFLTATFLVIYPEVSEEPKEEQKGLSSGPAGEGEGGAGSEKPTVLKLSRKGGLRGLVETESMV
uniprot
proteins
function
FUNCTION: Neuronal polyamine-transporter involved in pain perception (PubMed:40836097). Transports polyamines such as putrescine, cadaverine, spermine and spermidine (By similarity). Expressed in sensory neuron subtypes within the dorsal root ganglion, where it regulates the excitability of C-polymodal nociceptors by mediating polyamine transport (PubMed:40836097). {ECO:0000250|UniProtKB:Q5BKX6, ECO:0000269|PubMed:40836097}.
uniprot
proteins
mass_dalton
85765
uniprot
proteins
protein_family
Glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25164149
uniprot
proteins
pubmed
40836097
uniprot
proteins
sequence_length
785
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5BKX6}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 50..80; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 90..112; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 121..147; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 156..187; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 193..216; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 222..252; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 511..552; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 566..600; /note="Helical; Name=8"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 607..627; /note="Helical; Name=9"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 631..666; /note="Helical; Name=10"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 677..706; /note="Helical; Name=11"; /evidence="ECO:0000250|UniProtKB:Q5BKX6"; TRANSMEM 709..729; /note="Helical; Name=12"; /evidence="ECO:0000250|UniProtKB:Q5BKX6
uniprot
proteins