Cp
entrez
12870
canonical
uniprot
Q61147
canonical
ensembl
ENSMUSG00000003617
resolver
ensp
ENSMUSP00000003714
resolver
ensp
ENSMUSP00000088857
resolver
ensp
ENSMUSP00000103961
resolver
ensp
ENSMUSP00000103964
resolver
ensp
ENSMUSP00000103965
resolver
ensp
ENSMUSP00000293234
resolver
enst
ENSMUST00000003714
resolver
enst
ENSMUST00000091309
resolver
enst
ENSMUST00000108325
resolver
enst
ENSMUST00000108328
resolver
enst
ENSMUST00000108329
resolver
genesymbol
Cp
resolver
uniprot
E9PZD8
resolver
uniprot
G3X8Q5
resolver
uniprot
G3X9T8
resolver
uniprot
Q6P5C8
resolver
uniprot
Q8BU82
resolver
uniprot_entry
CERU_MOUSE
resolver
uniprot_entry
E9PZD8_MOUSE
resolver
uniprot_entry
G3X8Q5_MOUSE
resolver
uniprot_entry
G3X9T8_MOUSE
resolver
uniprot_entry
Q8BU82_MOUSE
resolver
uniprot_sec
Q6P5C8
resolver
amino_acid_sequence
MKFLLLSTFIFLYSSLALARDKHYFIGITEAVWDYASGTEEKKLISVDTEQSNFYLQNGPDRIGRKYKKALYFEYTDGTFSKTIDKPAWLGFLGPVIKAEVEDKVYVHLKNLASRIYTFHAHGVTYTKEYEGAVYPDNTTDFQRADDKVLPGQQYVYVLHANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLYKEKEKNIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAADRVKWYLFGMGNEVDVHSAFFHGQALTSRNYQTDIINLFPATLIDAYMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPEDNIQDRHVRHYYIAAEEVIWNYAPSGTDIFTGENLTALESDSRVFFEQGATRIGGSYKKMAYREYTDGSFTNRKQRGPDEEHLGILGPVIWAEVGDTIKVTFHNKGQHPLSIQPMGVSFTAENEGTYYGPPGRSSQQAASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDPTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFPTVFDENESLLLDDNIRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMNPDTKGTFDVECLTTDHYTGGMKQKYTVNQCQRQFEDFTVYLGERTYYVAAVEVEWDYSPSRAWEKELHHLQEQNVSNVFLDKEEFFIGSKYKKVVYRQFTDSSFREQVKRRAEDEHLGILGPPIHANVGDKVKVVFKNMATRPYSIHAHGVKTESSTVVPTLPGEVRTYTWQIPERSGAGREDSACIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFSPKKKMEFFLLFLVFDENESWYLDDNIKTYSEHPEKVNKDNEEFLESNKMHAINGKMFGNLQGLTMHVKDEVNWYVMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHVHAGMATTYTVLPVEQETKSG
uniprot
proteins
ec_number
1.11.1.27
uniprot
proteins
ec_number
1.11.1.9
uniprot
proteins
ec_number
1.16.3.1
uniprot
proteins
ec_number
1.16.3.4
uniprot
proteins
function
FUNCTION: Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein (By similarity). It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species (By similarity). It is involved in iron transport across the cell membrane (By similarity). Copper ions provide a large number of enzymatic activities (By similarity). Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin (By similarity). Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1 (By similarity). Has glutathione peroxidase-like activity, can remove both hydrogen peroxide and lipid hydroperoxide in the presence of thiols (By similarity). Acts as an inhibitor of the peroxidase activity of MPO (PubMed:23306200). Also shows NO-oxidase and NO2 synthase activities that determine endocrine NO homeostasis (PubMed:29183916). {ECO:0000250|UniProtKB:P00450, ECO:0000250|UniProtKB:P13635, ECO:0000269|PubMed:23306200, ECO:0000269|PubMed:29183916}.
uniprot
proteins
mass_dalton
121151
uniprot
proteins
protein_family
Multicopper oxidase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16906150
uniprot
proteins
pubmed
16944957
uniprot
proteins
pubmed
17330941
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23306200
uniprot
proteins
pubmed
29183916
uniprot
proteins
pubmed
8690795
uniprot
proteins
sequence_length
1061
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16906150}. Note=Colocalizes with GCP1 in secretory intracellular compartments. {ECO:0000250|UniProtKB:P13635}.
uniprot
proteins