Cd7
entrez
12516
canonical
uniprot
P50283
canonical
ensembl
ENSMUSG00000025163
resolver
ensp
ENSMUSP00000026159
resolver
enst
ENSMUST00000026159
resolver
genesymbol
Cd7
resolver
uniprot
Q3U4A8
resolver
uniprot_entry
CD7_MOUSE
resolver
uniprot_entry
Q3U4A8_MOUSE
resolver
amino_acid_sequence
MTQQAVLALLLTLAGILPGPLDAQDVHQSPRLTIASEGDSVNITCSTRGHLEGILMKKIWPQAYNVIYFEDRQEPTVDRTFSGRINFSGSQKNLTITISSLQLADTGDYTCEAVRKVSARGLFTTVVVKEKSSQEAYRSQEPLQTSFSFPAAIAVGFFFTGLLLGVVCSMLRKIQIKKLCASGIKESPCVVYEDMSYSNRKTPCIPNQYQ
uniprot
proteins
function
FUNCTION: Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of gamma-interferon levels. {ECO:0000250|UniProtKB:P09564}.
uniprot
proteins
mass_dalton
23153
uniprot
proteins
pubmed
10075985
uniprot
proteins
pubmed
10652336
uniprot
proteins
pubmed
7509775
uniprot
proteins
pubmed
7528728
uniprot
proteins
pubmed
7678579
uniprot
proteins
pubmed
9637484
uniprot
proteins
sequence_length
210
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 151..171; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins