TDRD5
entrez
163589
canonical
uniprot
Q8NAT2
canonical
ensembl
ENSG00000162782
resolver
ensp
ENSP00000294848
resolver
ensp
ENSP00000356586
resolver
ensp
ENSP00000406052
resolver
ensp
ENSP00000567537
resolver
ensp
ENSP00000588911
resolver
genesymbol
TDRD5
resolver
genesymbol_syn
TUDOR3
resolver
hgnc
HGNC:20614
resolver
uniprot
A0A024R910
resolver
uniprot
A0A140VJW7
resolver
uniprot
A1L4G5
resolver
uniprot
B7ZLV0
resolver
uniprot
Q5EBN4
resolver
uniprot
Q5VTV0
resolver
uniprot
Q6ZSK2
resolver
uniprot_entry
A0A024R910_HUMAN
resolver
uniprot_entry
TDRD5_HUMAN
resolver
uniprot_sec
A0A140VJW7
resolver
uniprot_sec
A1L4G5
resolver
uniprot_sec
B7ZLV0
resolver
uniprot_sec
Q5EBN4
resolver
uniprot_sec
Q5VTV0
resolver
uniprot_sec
Q6ZSK2
resolver
amino_acid_sequence
MSEQERIQECLRKEIRSLLISTKDGLSPQELEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVRVCPGAGGTVILKAIPDESTKGIASLVAKQRSSHKLRNSMHKGRPSIYSGPRSHRRVPYRGRVAPILPAVVKSELKDLLALSPVLLSDFEKAFAKRFGRSFQYMQYGFLSMFEVLNAASDVISVEQTRAGSLLMLKKSVTEEKPRGCPAGKIFTQPFRMKQGSYSTGFPVAKPCFSQPTSNMEPPKQIMSMEKTSKLNVVETSRLNHTEKLNQLENTFKSVIAQIGPGGTISSELKHKIKFVVSKFPEGLFISKLLGEYEVIFKEQLSPKKLGFLNVTELVGALSDILHVEFRKGHQDLLVFDADKKPLPPVQSDKKIEAKACVSSPPRNSLSTAAVKETVWNCPSKKQKEPQQKICKKPNLVVKPLQLQVETNKSELNLAMANHDIPPDAVPNKKLCRLPPLDTSSLIGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENISSKGFSELNPLALYTTSSGGPEDIVLTELGYPSQQHYFNEDRKISPQSKESELRILDEIPTGMPCLESVTIGDDIWDENWLPLQAKMGKGGDAASHLFTASLGGKNQYSSCKEMPQKDWCFSTPKDTWDDSWQPSGLVNGTKVEVHKPEVLGAQEKNTGTNRTQKQLDINGSSDSSTLPKLEEFCTSLTQSEQSADGSQSEPNNSQTQPKQIQLSTAAPCSTTAVDDSAEKPSGSVESSPEILKNEDFSSSRAITLYKDKRQESVDQLSLILSYECQISQKLYIPRSTATAALGAAARLATSRSLLHWYPSVKRMEA
uniprot
proteins
function
FUNCTION: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
109737
uniprot
proteins
protein_family
TDRD5 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
20302647
uniprot
proteins
pubmed
20305267
uniprot
proteins
sequence_length
981
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. {ECO:0000250}.
uniprot
proteins