SEMA4C
entrez
54910
canonical
uniprot
Q9C0C4
canonical
ensembl
ENSG00000168758
resolver
ensp
ENSP00000306844
resolver
ensp
ENSP00000567333
resolver
ensp
ENSP00000567335
resolver
ensp
ENSP00000567339
resolver
ensp
ENSP00000567340
resolver
ensp
ENSP00000567342
resolver
ensp
ENSP00000567343
resolver
ensp
ENSP00000567346
resolver
ensp
ENSP00000567348
resolver
ensp
ENSP00000567350
resolver
ensp
ENSP00000567353
resolver
ensp
ENSP00000567354
resolver
ensp
ENSP00000567355
resolver
ensp
ENSP00000567356
resolver
ensp
ENSP00000584364
resolver
ensp
ENSP00000584375
resolver
ensp
ENSP00000584377
resolver
enst
ENST00000305476
resolver
enst
ENST00000897274
resolver
enst
ENST00000897280
resolver
enst
ENST00000897281
resolver
enst
ENST00000897283
resolver
enst
ENST00000897284
resolver
enst
ENST00000897287
resolver
enst
ENST00000897289
resolver
enst
ENST00000897291
resolver
enst
ENST00000897294
resolver
enst
ENST00000897295
resolver
enst
ENST00000897296
resolver
enst
ENST00000897297
resolver
enst
ENST00000914305
resolver
enst
ENST00000914316
resolver
enst
ENST00000914318
resolver
genesymbol
SEMA4C
resolver
genesymbol_syn
KIAA1739
resolver
genesymbol_syn
SEMAI
resolver
hgnc
HGNC:10731
resolver
uniprot
Q32MJ3
resolver
uniprot
Q7Z5X0
resolver
uniprot_entry
SEM4C_HUMAN
resolver
uniprot_sec
Q32MJ3
resolver
uniprot_sec
Q7Z5X0
resolver
amino_acid_sequence
MAPHWAVWLLAARLWGLGIGAEVWWNLVPRKTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKATERTLVYPLELPKEPTSPPFRPCPEPDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGLGHPLPELADELRRKLQQRQPLPDSNPEESSV
uniprot
proteins
function
FUNCTION: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. {ECO:0000250, ECO:0000269|PubMed:17498836}.
uniprot
proteins
mass_dalton
92623
uniprot
proteins
protein_family
Semaphorin family
uniprot
proteins
pubmed
11214970
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17498836
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
833
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic density membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 664..684; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins