MLDHR
entrez
133834869
canonical
uniprot
C0HLV8
canonical
ensembl
ENSG00000289051
resolver
ensp
ENSP00000509326
resolver
enst
ENST00000692337
resolver
genesymbol
MLDHR
resolver
genesymbol_syn
MP31
resolver
hgnc
HGNC:55481
resolver
uniprot_entry
MP31_HUMAN
resolver
amino_acid_sequence
MWRDSLCAAAGYALGAGTRLRSVLSSRKLQP
uniprot
proteins
function
FUNCTION: Inhibits lactate dehydrogenase (LDH)-mediated conversion of lactate to pyruvate in mitochondria by competing with mitochondrial LDH for binding to NAD(+) (PubMed:33406399). Also inhibits cellular lactate utilization (PubMed:33406399). {ECO:0000269|PubMed:33406399}.
uniprot
proteins
mass_dalton
3336
uniprot
proteins
mutagenesis
MUTAGEN 5; /note="S->A: Abolishes interaction with LDHA and LDHB."; /evidence="ECO:0000269|PubMed:33406399"; MUTAGEN 12; /note="Y->A: Abolishes interaction with LDHA and LDHB."; /evidence="ECO:0000269|PubMed:33406399
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
33406399
uniprot
proteins
pubmed
33535099
uniprot
proteins
sequence_length
31
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:33406399}.
uniprot
proteins