Acot7
entrez
70025
canonical
uniprot
Q91V12
canonical
ensembl
ENSMUSG00000028937
resolver
ensp
ENSMUSP00000030779
resolver
ensp
ENSMUSP00000074827
resolver
ensp
ENSMUSP00000101277
resolver
ensp
ENSMUSP00000129121
resolver
ensp
ENSMUSP00000209995
resolver
enst
ENSMUST00000167926
resolver
genesymbol
Acot7
resolver
genesymbol_syn
Bach
resolver
uniprot
A2A8K9
resolver
uniprot
A2A8L0
resolver
uniprot
A2A8L2
resolver
uniprot
E9PYH2
resolver
uniprot
Q3U8C6
resolver
uniprot
Q59HQ2
resolver
uniprot_entry
BACH_MOUSE
resolver
uniprot_entry
E9PYH2_MOUSE
resolver
uniprot_sec
A2A8K9
resolver
uniprot_sec
A2A8L0
resolver
uniprot_sec
A2A8L2
resolver
uniprot_sec
Q3U8C6
resolver
uniprot_sec
Q59HQ2
resolver
amino_acid_sequence
MKLLVGTLRLWEVGRQVAFSSLTPGQECSGLRKTFWAAMRAVRTRADHQKLGHCVTMGRIMRPDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEVQVHVMSENILTGTKKLTNKATLWYVPLSLKNVDKVLEVPPIVYLRQEQEEEGRKRYEAQKLERMETKWRNGDIVQPVLNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDNSQKRYRAASAFFTYVSLNQEGKPMPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHTEPQP
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (Probable). Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18 (Probable). May play an important physiological function in brain (Probable). {ECO:0000305|PubMed:15288813}.
uniprot
proteins
mass_dalton
42537
uniprot
proteins
mutagenesis
MUTAGEN 67; /note="N->A: Dramatic reduction in catalytic activity."; /evidence="ECO:0000269|PubMed:17563367"; MUTAGEN 256; /note="D->A: Dramatic reduction in catalytic activity."; /evidence="ECO:0000269|PubMed:17563367
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid metabolism. {ECO:0000305|PubMed:15288813}.
uniprot
proteins
pubmed
11834298
uniprot
proteins
pubmed
12435388
uniprot
proteins
pubmed
14729242
uniprot
proteins
pubmed
15288813
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17563367
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
381
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform A]: Cytoplasm, cytosol {ECO:0000305|PubMed:15288813}.; SUBCELLULAR LOCATION: [Isoform D]: Cytoplasm, cytosol {ECO:0000305|PubMed:15288813}.
uniprot
proteins