Tmprss11d
entrez
64565
canonical
uniprot
Q8VHJ4
canonical
ensembl
ENSRNOG00000055991
resolver
ensp
ENSRNOP00000073795
resolver
enst
ENSRNOT00000088552
resolver
genesymbol
Tmprss11d
resolver
genesymbol_syn
Rat
resolver
uniprot
G3V691
resolver
uniprot
Q9QZ74
resolver
uniprot_entry
G3V691_RAT
resolver
uniprot_entry
TM11D_RAT
resolver
uniprot_sec
Q9QZ74
resolver
amino_acid_sequence
MYRPRSMVSPSRFFNPFMVALIVIITVGLLAMTAGLLIHFLAFDKRAYFYHSNFHILNVDYTEALNSPATHEYRTLSERIESMITDAFRESNLRSEFIRTHVVKLRKEGSGVVADVVMKFRSSKRNNKKAIKTRIQSVLQRLSSSGNLEIAPSNGITSLTDQDTENVLTQECGARPDLITLSEERIIGGTQAETGDWPWQVSLQLNNVHHCGGTLISNLWVLTAAHCFRSYSNPQQWTATFGVSTISPRLRVRVRAILAHAEYNSITRDNDIAVVQLDRPVTFTRNIHRVCLPAATQNIMPDSVAYVTGWGSLTYGGNTVTNLQQGEVRIVSSEVCNEPAGYGGSVLPGMLCAGVRSGAVDACQGDSGGPLVQEDTRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQQTGI
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Preferentially cleaves the C-terminal side of arginine residues at the P1 position of certain peptides (By similarity). Isoform 2 may play a key role in regulating adrenal proliferation by specifically cleaving N-POMC. {ECO:0000250, ECO:0000269|PubMed:11439186}.
uniprot
proteins
mass_dalton
46288
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
11439186
uniprot
proteins
pubmed
14691009
uniprot
proteins
sequence_length
417
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Transmembrane protease serine 11D catalytic chain]: Secreted {ECO:0000250}. Note=Activated by cleavage and secreted. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins