Ntaq1
entrez
362914
canonical
uniprot
Q5BJV9
canonical
ensembl
ENSRNOG00055025512
resolver
ensembl
ENSRNOG00060003468
resolver
ensp
ENSRNOP00055036036
resolver
ensp
ENSRNOP00060004153
resolver
enst
ENSRNOT00055044054
resolver
enst
ENSRNOT00060005694
resolver
genesymbol
Ntaq1
resolver
genesymbol_syn
Wdyhv1
resolver
uniprot_entry
NTAQ1_RAT
resolver
amino_acid_sequence
MEGDSRAATASQYQPACPTRDACVYSSCYCEENIWKLCEYIKTHNQYLLEECYAVFISNEKKMVPIWKQQARPENGPVIWDYHVVLLHVSREGQSFIYDLDTILPFPCPFDIYIEDALKSDDDIHPQFRRKFRVVRADSYLKNFASDRSHMKDSSGNWREPPPEYPCIETGDSKMNLNDFISMDPAVGWGAVYTLSEFVHRFSSKNY
uniprot
proteins
ec_number
3.5.1.122
uniprot
proteins
function
FUNCTION: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine. {ECO:0000250|UniProtKB:Q80WB5}.
uniprot
proteins
mass_dalton
24125
uniprot
proteins
protein_family
NTAQ1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
207
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q80WB5}. Nucleus {ECO:0000250|UniProtKB:Q80WB5}.
uniprot
proteins