Erf
entrez
13875
canonical
uniprot
P70459
canonical
ensembl
ENSMUSG00000040857
resolver
ensp
ENSMUSP00000041912
resolver
enst
ENSMUST00000045847
resolver
genesymbol
Erf
resolver
uniprot
A0A0R4J0I0
resolver
uniprot
Q3TXK4
resolver
uniprot
Q6P544
resolver
uniprot
Q7TSJ1
resolver
uniprot_entry
A0A0R4J0I0_MOUSE
resolver
uniprot_entry
ERF_MOUSE
resolver
uniprot_sec
Q3TXK4
resolver
uniprot_sec
Q6P544
resolver
uniprot_sec
Q7TSJ1
resolver
amino_acid_sequence
MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFIDMGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARRLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPELGAFRGPPLARLPHDPGVFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGGSHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPVPSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAPGGTDKSSGGSGSGGLAEGAGAVAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGVAQCMPLKLRFKRRWSEDCRLEGGGCLSGGPEDEGEDKKVRGDVGPGESGGPLTPRRVSSDLQHATAQLSLEHRDS
uniprot
proteins
function
FUNCTION: Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation (By similarity). Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment. May be important for regulating trophoblast stem cell differentiation. {ECO:0000250, ECO:0000269|PubMed:17502352}.
uniprot
proteins
mass_dalton
59050
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by multiple kinases including MAPK1/ERK2 at THR-529. Phosphorylation regulates the activity of ERF (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
ETS family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17502352
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23354439
uniprot
proteins
pubmed
9136988
uniprot
proteins
sequence_length
551
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins