Pfn2
entrez
18645
canonical
uniprot
Q9JJV2
canonical
ensembl
ENSMUSG00000027805
resolver
ensp
ENSMUSP00000068890
resolver
genesymbol
Pfn2
resolver
uniprot
Q3TPT7
resolver
uniprot
Q3V171
resolver
uniprot
Q9ES48
resolver
uniprot
Q9ES49
resolver
uniprot
Q9ES50
resolver
uniprot_entry
PROF2_MOUSE
resolver
uniprot_sec
Q3TPT7
resolver
uniprot_sec
Q3V171
resolver
uniprot_sec
Q9ES48
resolver
uniprot_sec
Q9ES49
resolver
uniprot_sec
Q9ES50
resolver
amino_acid_sequence
MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPVEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
uniprot
proteins
function
FUNCTION: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
uniprot
proteins
mass_dalton
15032
uniprot
proteins
protein_family
Profilin family
uniprot
proteins
pubmed
11027290
uniprot
proteins
pubmed
11034907
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19403918
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
140
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
uniprot
proteins