Sapcd2
entrez
72080
canonical
uniprot
Q9D818
canonical
ensembl
ENSMUSG00000026955
resolver
ensp
ENSMUSP00000028329
resolver
ensp
ENSMUSP00000097898
resolver
ensp
ENSMUSP00000109932
resolver
genesymbol
Sapcd2
resolver
uniprot
A2AJ17
resolver
uniprot
Q3TL89
resolver
uniprot
Q3TP90
resolver
uniprot
Q3TQ24
resolver
uniprot
Q6NS42
resolver
uniprot_entry
SAPC2_MOUSE
resolver
uniprot_sec
A2AJ17
resolver
uniprot_sec
Q3TL89
resolver
uniprot_sec
Q3TP90
resolver
uniprot_sec
Q3TQ24
resolver
uniprot_sec
Q6NS42
resolver
amino_acid_sequence
MAVAAMAERGRLSHAAPAPSTEGLPRAFLQSLRTLFDILDDRQRGYVHLREIESRWQGADARELPCGVLEGLRQVAPANGYLTFERFVAGLRTSLLKADGGQRDQARVAARPGDQSSLQQRLMFAPADEPRTVLERKPLPLSACPASGGPSGTSRNPELLCVPVEAASCPTETERPLSKALEQIPSADLGAAACKTLGKGTGEARQAPRARGERRRHTITNGVDCSLLKQMKELDQEQEVLLQGLEMMARGRDWYQQQLQRVQERQRRLSQSRAAADFGAEGSPRPLGRLLPKVQEVARCLGELLTAACSGRALPSSSLGPLGPPSPSTPVWQQQTILMLKEQNRLLTQEVTDKSERITQLEQEKSALIKQLFEARALSQQDSGPLDSTFI
uniprot
proteins
function
FUNCTION: Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (PubMed:26766442). Negatively regulates the mitotic apical cortex localization of GPSM2 (By similarity). Involved also in positive regulation of cell proliferation and tumor cell growth (By similarity). {ECO:0000250|UniProtKB:Q86UD0, ECO:0000269|PubMed:26766442}.
uniprot
proteins
mass_dalton
42780
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15567712
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
26766442
uniprot
proteins
sequence_length
391
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86UD0}. Nucleus {ECO:0000250|UniProtKB:Q86UD0}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q86UD0}. Apical cell membrane {ECO:0000269|PubMed:26766442}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q86UD0}. Note=Localized at the apical membrane during the M phase (PubMed:26766442). In horizontally retinal progenitor dividing cells, localized at the pole cortical region from prophase to telophase cells (PubMed:26766442). In vertically retinal progenitor dividing cells, not detected at the pole cortical region at any stage of mitosis (PubMed:26766442). {ECO:0000269|PubMed:26766442}.
uniprot
proteins