Mlip
entrez
69642
canonical
uniprot
Q5FW52
canonical
ensembl
ENSMUSG00000032355
resolver
ensp
ENSMUSP00000034910
resolver
ensp
ENSMUSP00000138864
resolver
ensp
ENSMUSP00000139055
resolver
ensp
ENSMUSP00000139109
resolver
ensp
ENSMUSP00000139242
resolver
ensp
ENSMUSP00000139251
resolver
ensp
ENSMUSP00000189691
resolver
ensp
ENSMUSP00000189695
resolver
ensp
ENSMUSP00000189696
resolver
ensp
ENSMUSP00000189699
resolver
ensp
ENSMUSP00000189700
resolver
ensp
ENSMUSP00000189702
resolver
ensp
ENSMUSP00000189703
resolver
ensp
ENSMUSP00000189704
resolver
ensp
ENSMUSP00000189712
resolver
ensp
ENSMUSP00000189713
resolver
ensp
ENSMUSP00000189714
resolver
ensp
ENSMUSP00000189715
resolver
ensp
ENSMUSP00000189718
resolver
ensp
ENSMUSP00000189721
resolver
ensp
ENSMUSP00000189725
resolver
ensp
ENSMUSP00000189728
resolver
ensp
ENSMUSP00000189730
resolver
ensp
ENSMUSP00000189731
resolver
ensp
ENSMUSP00000189732
resolver
ensp
ENSMUSP00000189734
resolver
ensp
ENSMUSP00000189739
resolver
ensp
ENSMUSP00000189741
resolver
ensp
ENSMUSP00000189743
resolver
ensp
ENSMUSP00000189754
resolver
ensp
ENSMUSP00000351749
resolver
ensp
ENSMUSP00000351753
resolver
ensp
ENSMUSP00000351756
resolver
genesymbol
Mlip
resolver
genesymbol_syn
Cip
resolver
uniprot
B7ZMP8
resolver
uniprot
Q9D6X9
resolver
uniprot
V9GWW6
resolver
uniprot_entry
MLIP_MOUSE
resolver
uniprot_sec
B7ZMP8
resolver
uniprot_sec
Q9D6X9
resolver
uniprot_sec
V9GWW6
resolver
amino_acid_sequence
MTSCILAGSLETTPKVSPGDPEAKPLIFTFVPTLRRLPTHIQLADTSKFLVKIPEEPTDKSPETVNRFEYSDHMTFSSESKQERVQRILDYPSEVSGRNSQQKEFNTKEPQGMQKGDLFKAEYVFIVDSDGEDEATCRQGEQGPPGGPGNIATRPKSLAISSSLASDVVRPKVRGADLKTSSHPEIPHGIAPQQKHGLLISPTTSEQLAHKPPAFSFVSPTNQKTPPVPANVSGATVLREFHTRRLDVTGASEEETTTYFHSTAHDSPLSAWKGASTLVVSPSAQLSGSSLCGSNVTDHTRGLASEAQKKMSTSNVLNPKEDVRTCPAPASGASLTSPSASYIPVRIVMHSLSPSPKPLTSSSHGSLSTVCSQMSSSGSLSKSGLKSPVPSRLSLLTAILKSNPSHQRPLSPASCPTFSLNSLASSTLALDQKVKQTPPTSKKSLSSGSLTTGSTEQEHQASAASYQPCHLPFFSKTTPLSQAQPLSPLALASNSCASMDIEKIPGSTLRSNTTSPQPQTDTFSLADVPSVTPVLSPLSSSKGRKDGDSRTPEKNRNICIQPSTLASTPPVDESLALSSSGKGFHPSPALSDLIDRSKRACSQQHPGQRPSPSALPTPPVSRAASASHPHLGCSILPLQSSLTQTLQPSPSALRPSCGSATCPSRTQMPENTASNHSSRVSTPSLPVSLTRTKELFSPCALSMSAGPENKKPKQYKTMSSYKAFAAIPTNTLLLEQKALDEPARTESNSKASVLDLPVEFCFPAQLRQQTEELCATIDKVLQDSLSMHSSDSPSRPPQTMLGSETIKTPTTHPRAAGRETKYANLSSSSSTASESQLTKPGVIRPVPVKSKLLLRKDEEVYEPNPFSKYLEDNSGLFSEQDMAIPHKPVSLHPLYQSKLYPPAKSLLHPQTLSHADCLTPGSFSHLSSFSVRDEQEKSPTLLSQDTYNKLGHPMVTIPEHDTLDSKE
uniprot
proteins
function
FUNCTION: Required for myoblast differentiation into myotubes, possibly acting as a transcriptional regulator of the myogenic program (PubMed:33802236). Required for cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays a role in the protection against cardiac hypertrophy (PubMed:22343712, PubMed:26359501, PubMed:26436652). Binds chromatin (PubMed:33802236). May act as a transcriptional cofactor for ISL1, repressing its transcriptional activity (PubMed:22343712). May also repress MYOCD transcriptional activity (PubMed:22343712). {ECO:0000269|PubMed:22343712, ECO:0000269|PubMed:26359501, ECO:0000269|PubMed:26436652, ECO:0000269|PubMed:33802236}.
uniprot
proteins
mass_dalton
103448
uniprot
proteins
post_translational_modification
PTM: May be ubiquitinated by UBE3C ubiquitin ligase; ubiquitination is followed by protein degradation. {ECO:0000269|PubMed:36112854}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21498514
uniprot
proteins
pubmed
22343712
uniprot
proteins
pubmed
26359501
uniprot
proteins
pubmed
26436652
uniprot
proteins
pubmed
30389785
uniprot
proteins
pubmed
33802236
uniprot
proteins
pubmed
36112854
uniprot
proteins
sequence_length
967
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21498514, ECO:0000269|PubMed:22343712, ECO:0000269|PubMed:26436652, ECO:0000269|PubMed:33802236}. Nucleus envelope {ECO:0000269|PubMed:21498514}. Nucleus, PML body {ECO:0000269|PubMed:21498514}. Cytoplasm, cytosol {ECO:0000269|PubMed:21498514, ECO:0000269|PubMed:22343712, ECO:0000269|PubMed:26436652}. Cell membrane, sarcolemma {ECO:0000269|PubMed:26359501}; Peripheral membrane protein {ECO:0000269|PubMed:26359501}; Cytoplasmic side {ECO:0000269|PubMed:26359501}.
uniprot
proteins