P97382
uniprot
P97382
canonical
amino_acid_sequence
MSRGYGLIFSLKVVFTFLSLPHPPGLQGSLDRLQLEYVDIVFANRSDPNSPMEEIVRAMTYVINQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHKIGVGSVTWSPLACGLITSKYDGRVPDTCKATVKGYQWLKEKVQSEEGKKQQARVMDLLPTARQLGCTVGQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLSQLTPQTVVEIDALLGNKSHSKK
uniprot
proteins
ec_number
1.1.1.-
uniprot
proteins
function
FUNCTION: Regulatory subunit of the voltage-gated potassium (Kv) channels composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunit (PubMed:8824288). The beta-3/KCNAB3 subunit may mediate closure of potassium channels (By similarity). Enhances the expression of Kv2.2/KCNB2 alpha subunit-containing Kv channels but not Kv2.1/KCNB1 (PubMed:8824288). May display nicotinamide adenine dinucleotide phosphate (NADPH)-dependent aldoketoreductase activity (By similarity). The binding of oxidized and reduced NADP(H) cofactors may be required for the regulation of potassium channel activity (By similarity). {ECO:0000250|UniProtKB:P63144, ECO:0000269|PubMed:8824288}.
uniprot
proteins
mass_dalton
27749
uniprot
proteins
protein_family
Shaker potassium channel beta subunit family
uniprot
proteins
pubmed
8824288
uniprot
proteins
sequence_length
249
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins