Inf2
entrez
70435
canonical
uniprot
Q0GNC1
canonical
ensembl
ENSMUSG00000037679
resolver
ensp
ENSMUSP00000098591
resolver
enst
ENSMUST00000101029
resolver
genesymbol
Inf2
resolver
uniprot
E9QLA5
resolver
uniprot
Q14C56
resolver
uniprot
Q499F7
resolver
uniprot
Q6P9T3
resolver
uniprot_entry
E9QLA5_MOUSE
resolver
uniprot_entry
INF2_MOUSE
resolver
uniprot_sec
Q14C56
resolver
uniprot_sec
Q499F7
resolver
uniprot_sec
Q6P9T3
resolver
activity_regulation
ACTIVITY REGULATION: Phosphate inhibits both the depolymerization and severing activities. {ECO:0000269|PubMed:16818491}.
uniprot
proteins
amino_acid_sequence
MSVKEGAQRKWAALKEKLGPQDSDPTEANLESAEPELCIRLLQMPSVVNYSGLRKRLESSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCISCVRAVMNSQQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHALTLDALDHYKMVCSQQYRFSVIMSELSDSDNVPYVVTLLSVINAIILGPEDLRSRAQLRSEFIGLQLLDILTRLRDLEDADLLIQLEAFEEAKAEDEEELQRISDGINMNSHQEVFASLFHKVSCSPASAQLLSVLQGLMHLEPAGRSGQLLWEALENLVNRAVLLASDAQACTLEEVVERLLSIKGRPRPSPLDKAHKSVQTNSVQNQGSSSQNTTTPTTKVEGQQPVVASPCQHVGSIQSSSVDIAPQPVALEQCITALPLPTPPLSSSTPVLPPTPPPLPGPGATSPLPPPPPPLPPPLPGSGTTSPPPPPPPPPPLPPPLPGSGTISPPPPPPPPPLPGTGAVSPPPPPPLPSLPDSHKTQPPPPPPPPLPGMCPVPPPPPLPRAGQIPPPPPLPGFSVPSMMGGVEEIIVAQVDHSLGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVARERNSMWATLGSPCTAAVEPDFSSIEQLFSFPTAKPKEPSAAPARKEPKEVTFLDSKKSLNLNIFLKQFKCSNEEVTSMIQAGDTSKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLSNADQFYVLLLDIPCYPLRVECMMLCEGTAIVLDMVRPKAQLVLTACESLLTSQRLPVFCQLILKIGNFLNYGSHTGDADGFKISTLLKLTETKSQQSRVTLLHHVLEEVEKSHPDLLQLSRDLEPPSQAAGINVEIIHSEASANLKKLLEAERKVSASIPEVQKQYAERLQASIEASQELDKVFDAIEQKKLELADYLCEDPQQLSLEDTFSTMKTFRDLFTRALKENKDRKEQMAKAERRKQQLAEEEARRPRDEDGKPIRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTEASGRVAPTDPPKATEPATASNPTQGTNHPASEPLDTTAADEPQGWDLVDAVTPSPQPSKEEDGPPALERRSSWYVDAIDFLDPEDTPDAQPSEGVWPVTLGDGQALNPLEFSSNKPPGVKSSHQDATDPEALWGVHQTEADSTSEGPEDEAQRGQSTHLPRTGPGEDEDGEDTAPESALDTSLDRSFSEDAVTDSSGSGTLPRVQGRVSKGTSKRRKKRPSRNQEEFVPDSDDIKAKRLCVIQ
uniprot
proteins
function
FUNCTION: Severs actin filaments and accelerates their polymerization and depolymerization. {ECO:0000269|PubMed:16818491}.
uniprot
proteins
mass_dalton
138560
uniprot
proteins
mutagenesis
MUTAGEN 1009; /note="L->A: Strongly inhibits depolymerization; when associated with A-1010 and A-1019."; /evidence="ECO:0000269|PubMed:16818491"; MUTAGEN 1010; /note="L->A: Strongly inhibits depolymerization; when associated with A-1009 and A-1019."; /evidence="ECO:0000269|PubMed:16818491"; MUTAGEN 1019; /note="L->A: Strongly inhibits depolymerization; when associated with A-1009 and A-1010."; /evidence="ECO:0000269|PubMed:16818491
uniprot
proteins
protein_family
Formin homology family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16818491
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250}.
uniprot
proteins