Tasor2
entrez
105203
canonical
uniprot
Q5DTT3
canonical
ensembl
ENSMUSG00000033799
resolver
ensp
ENSMUSP00000093774
resolver
enst
ENSMUST00000096069
resolver
genesymbol
Tasor2
resolver
genesymbol_syn
Fam208b
resolver
genesymbol_syn
Kiaa2006
resolver
genesymbol_syn
Pap20
resolver
uniprot
O35330
resolver
uniprot
Q0P5P9
resolver
uniprot
Q3UUS0
resolver
uniprot
Q5U5L9
resolver
uniprot
Q6DI89
resolver
uniprot
Q6ZQM5
resolver
uniprot
Q91W76
resolver
uniprot_entry
TASO2_MOUSE
resolver
uniprot_sec
O35330
resolver
uniprot_sec
Q0P5P9
resolver
uniprot_sec
Q3UUS0
resolver
uniprot_sec
Q5U5L9
resolver
uniprot_sec
Q6DI89
resolver
uniprot_sec
Q6ZQM5
resolver
uniprot_sec
Q91W76
resolver
amino_acid_sequence
MAAPTSKIILELNKNALISPWKGQFIIQGCLLCDITLWSTYGTVVPLQLPRELDFKYVMDVSSLKESLPEAAFRRRSYLEQKVCCQDLCFDLYEVELTNKQGENIDKLMEYVKNKELALIKCLEDKSFFILFTSSALTPEPGFGAEQMGLHGLHLFHAPQTAGAKDLKVEDGISLKVIPILPALSYALLEAKKSLSEEGIPPNILVKHSFQELYKVDKSLSLMAPPQDGVEDTASTGKLSHAFDLPPPLETCPSESLTHLKCYFSDPAGYTLDLSAALDLLAEHPQFPCIADGVCDAGFSLVMTPDPEFLDSEMEIRKTETAEKSGRKLKVKKKAVTPSSNQRVQPKRKASTTAVTLPSKRVSLGRPTSKRTVPRTDNRSCNPTLKLVKGQFPQKRKRGAEVLAAQIVQKTRLERKKQEASVSKDAPVPTNTKRAKKQEKSPGRIASQPKPPMKKSPQKRKVNVARGRRNTRKQLQPAEKEIALHLQSEISSDGQKDGLNLSTSQQESISMIPKGPPENSVISCDSQALNMLADLALSSAAASIPSCKPRNLPCVSDLPRNNVLLTKENPLLGASDHEYHKGVKSQKAVLLPKPYSDEKISSESDLTRSQEENLVPCAQPLPIAQPAPHSEARELSDASQNSVVVEHSYALLLAEQSQKHLHQRKLPSPAFVKNGIKGPEAGTPVGKVMPFRHLQNTSPLQKHSEDSLMKHKSLFVSSTLKEFFCSHTVLKCDGSFKITFKCEGEYVFSLDSKYTSNPLEKTVLRALHGPWNTDLPENVDDVKLLLHIWVALFYSKNNKVIGSPRKVVEHKNPAKYVCINRSLESLDHSEIEAFSNVERPSVEGSVDPLLETKETHIGHATNMTFPGPNRVLPFINPPTTRDLELCVQNDQKEVFTGECHLDTSGNQNFIYSCNTEVTGGKTKQELSNKLETSNVVLSGVVSAQSHGTCIPSEDKTCQSTKMVSYNDSVTQATLTTAYDEASSELMCQKSVFDNLENKVDSFHPSPLIKTDAVQDVIQHSSHINNECQPSVEKREDNVECMMVNLDPVTLAFEKNASVPIHTEVHTTDKPTGFNIELVKRVSPASSVQYPMSALEEVQTQSSRDVPSLAMSEYKDSKCLSASSVKKETPPESLCLLQKEIPPLTSSADEGLIMEALSLVKSSSYSLASDKTKCPQDDSLQTQNGLSMSLDEVLEPSKVNVVSSTSVTLREQPSPNCIPAMSDVAGASTVIMNSGSSSLNQEKILQTFSLVFPKQTDLSLKREEVSMELSGEEADINLTLTISPPTSPSEEIAAGEIEQFQKTPVSNVGQQSRSEEMVEPEEEERLIRNREINSASCMSVYPVESRELLKNCTPEVTEKVNVTLDFPFGPLIEVSPASSPDPIVQPGDRPSSPCCLKLHSSQSEKTNKFSQIKSGEVTIPEKESLFLGPESPKGQDKLAEVQVQISAEMLQITTNAEVEGRVNMPGKVTKVSVPSEHSENLSFLEKVQCNTELNELSLPAKYGGNFKPLEKSGNSLEAGCMENRNVDVKHLALESSVPSCSPRKVVENKSLTDTLVSITTSGIVNMSLKQTSSKNIKKNVCDSDVKTDSDVKTEADSNMQTEAVNSALIDKTDVQAYSHPEVSKFVSSSDSAQCTYHAKPVSVEPGFQTQEIPVVRMASLLKNIGVELHEEKMDLSATGLQSNSMSAKDEQKTMHVLQDTICEVKEFLNGDVFSQNAHSCQNTVDFSKSISEEPSASFVPEFVDAICGVYKEHTFNESPNMVHETKADAETLSRNTEISVNASMFCGPRSGAYVQDSHDCKSCKFDVENLRGNHESQKDAVKDSCDSFTSLNNSDDTWACSSKISTLETHIPPRDQETEPRLISPNKCIPRYIQIPDSHGIPKTYANFTITKEFKDTTRRLHSLKRHRNLSANCNLLSSWTSTWHVTDDLTQHTLDLEYLRFDHKLKQIKKGGSQQSSFPKESLVQISSGTSPSTQTSEASGLHLPPESRSPILVTVVRADTRQQSHHRRGCSPSSLDGSSSFWKKKCSQSRNLKNSERSQTVPFHLNKLKYNSTLKESRNDISLILNEYAEFNKIMMNSKQIVSQDEELNVASAEAVFQEAYQPRQPVSYEDVITDLCATLHVKLKGVVREACKSPFWFYLVETEDKSFLLRTKSILKKGGHIEIELLDFCQAFHRENETLLVIIKNEDIISHLHQIPSLLKLKHFPSVVFAGVDSPEDIVNETYQELFRSGGFVVSDDVILESLTLVQLKEILKILEKLNENGKWKWLLHYRESKNLKEDVRVDSIAHKKNLILKSYQSVNIIDLLHYHNCDSPSSTKAEIFKCLLNLQIQHISARFAVFLTDKPTVSTEIFENNGILVTDVNYFTENIQKIAAPFRSSYW
uniprot
proteins
function
FUNCTION: Core component of the HUSH2 complex, a multiprotein complex that mediates epigenetic repression of interferon-stimulated genes (By similarity). TASOR2 is recruited to interferon-stimulated genes by IRF2, leading to transcriptional silencing by the HUSH2 complex via a H3K9me3-independent mechanism (By similarity). Within the HUSH2 complex, TASOR2 acts as the central scaffold, which recruits MPHOSPH8 and PPHLN1 (By similarity). {ECO:0000250|UniProtKB:Q5VWN6}.
uniprot
proteins
mass_dalton
264278
uniprot
proteins
protein_family
TASOR family
uniprot
proteins
pubmed
11731621
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
2382
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q5VWN6}. Chromosome {ECO:0000250|UniProtKB:Q5VWN6}. Note=Localizes to interferon-stimulated genes. {ECO:0000250|UniProtKB:Q5VWN6}.
uniprot
proteins