ATP5G1
entrez
516
canonical
uniprot
P05496
canonical
ensembl
ENSG00000159199
resolver
ensp
ENSP00000348205
resolver
ensp
ENSP00000377033
resolver
ensp
ENSP00000543747
resolver
ensp
ENSP00000608877
resolver
ensp
ENSP00000608879
resolver
ensp
ENSP00000608885
resolver
enst
ENST00000355938
resolver
enst
ENST00000393366
resolver
enst
ENST00000873688
resolver
enst
ENST00000938818
resolver
enst
ENST00000938820
resolver
enst
ENST00000938826
resolver
genesymbol
ATP5G1
resolver
genesymbol
ATP5MC1
resolver
genesymbol_syn
ATP5G1
resolver
hgnc
HGNC:841
resolver
uniprot
Q6FIH7
resolver
uniprot_entry
AT5G1_HUMAN
resolver
uniprot_entry
Q6FIH7_HUMAN
resolver
amino_acid_sequence
MQTAGALFISPALIRCCTRGLIRPVSASFLNSPVNSSKQPSYSNFPLQVARREFQTSVVSRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
uniprot
proteins
function
FUNCTION: Subunit c, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). With the subunit a (MT-ATP6), forms the proton-conducting channel in the F(0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane space (IMS) into the matrix (PubMed:37244256). Protons are taken up via the inlet half-channel and released through the outlet half-channel, following a Grotthuss mechanism (PubMed:37244256). {ECO:0000269|PubMed:37244256, ECO:0000305|PubMed:37244256}.
uniprot
proteins
mass_dalton
14277
uniprot
proteins
post_translational_modification
PTM: Trimethylated by ATPSCKMT at Lys-104. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. {ECO:0000269|PubMed:30530489}.
uniprot
proteins
protein_family
ATPase C chain family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2883974
uniprot
proteins
pubmed
30530489
uniprot
proteins
pubmed
31652072
uniprot
proteins
pubmed
33359711
uniprot
proteins
pubmed
37244256
uniprot
proteins
pubmed
8328972
uniprot
proteins
pubmed
8485160
uniprot
proteins
sequence_length
136
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 112..132; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins