CATSPERZ
entrez
25858
canonical
uniprot
Q9NTU4
canonical
ensembl
ENSG00000219435
resolver
ensp
ENSP00000491717
resolver
enst
ENST00000328404
resolver
genesymbol
CATSPERZ
resolver
genesymbol_syn
C11orf20
resolver
genesymbol_syn
TEX40
resolver
hgnc
HGNC:19231
resolver
uniprot_entry
CTSRZ_HUMAN
resolver
amino_acid_sequence
MEEKPSKVSLKSSDRQGSDEESVHSDTRDLWTTTTLSQAQLNMPLSEVCEGFDEEGRNISKTRGWHSPGRGSLDEGYKASHKPEELDEHALVELELHRGSSMEINLGEKDTASQIEAEKSSSMSSLNIAKHMPHRAYWAEQQSRLPLPLMELMENEALEILTKALRSYQLGIGRDHFLTKELQRYIEGLKKRRSKRLYVN
uniprot
proteins
function
FUNCTION: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel. {ECO:0000250|UniProtKB:Q9CQP8}.
uniprot
proteins
mass_dalton
22839
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
28226241
uniprot
proteins
sequence_length
200
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:28226241}; Peripheral membrane protein {ECO:0000305}. Note=Specifically located in the principal piece of sperm tail (PubMed:28226241). Although it does not contain a transmembrane domain, localizes with the CatSper complex at the flagellum membrane (PubMed:28226241). {ECO:0000269|PubMed:28226241}.
uniprot
proteins