EPB41L4B
entrez
54566
canonical
uniprot
Q9H329
canonical
ensembl
ENSG00000095203
resolver
ensp
ENSP00000363685
resolver
ensp
ENSP00000363694
resolver
ensp
ENSP00000603221
resolver
ensp
ENSP00000622272
resolver
ensp
ENSP00000622274
resolver
ensp
ENSP00000622275
resolver
ensp
ENSP00000622276
resolver
ensp
ENSP00000622277
resolver
genesymbol
EPB41L4B
resolver
genesymbol_syn
EHM2
resolver
genesymbol_syn
LULU2
resolver
hgnc
HGNC:19818
resolver
uniprot
Q59GC2
resolver
uniprot
Q5T4G5
resolver
uniprot
Q5T4G6
resolver
uniprot
Q9H328
resolver
uniprot
Q9NX84
resolver
uniprot
Q9P2V3
resolver
uniprot_entry
E41LB_HUMAN
resolver
uniprot_entry
Q59GC2_HUMAN
resolver
uniprot_entry
Q9NX84_HUMAN
resolver
uniprot_sec
Q5T4G5
resolver
uniprot_sec
Q5T4G6
resolver
uniprot_sec
Q9H328
resolver
uniprot_sec
Q9P2V3
resolver
amino_acid_sequence
MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHPSQPRWHPHSPNVSYPLPSPVLSSSDRLPFGIEENGGTPFLTAASGRHHHQHQHQHQHQHHSNYSLSLTLENKEGPLRSPNSSSKSLTKLSPGTPALFSEAAAHLKKLELETVKAAGPWPPLHININKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQGGKEESPFVNINKKSSLQDASVRSPIPIRVETAQPAVEKPEIKPPRVRKLTRQYSFDEDDLPPDLAEAVGVTTSTTTNTTTAATQVSVPLPSPKVQNVSSPHKSEGKGLLSPGAKSPSDRGGAFTLEPGDLLMDFTEATPLAEPASNPHCAHSRCSPPLSLPMKEETTGVCMYPPIKTRLIKTFPVDTMNPFPDTFTTGPQFTADFRDSKLQCCPGPTSPLIPAATLRPLTETVSTVQTIYTTRKPVSLAASAETLRQELEREKMMKRLLMTEL
uniprot
proteins
function
FUNCTION: Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927). {ECO:0000250|UniProtKB:Q9JMC8, ECO:0000269|PubMed:14521927, ECO:0000269|PubMed:22006950, ECO:0000269|PubMed:23664528}.
uniprot
proteins
mass_dalton
99712
uniprot
proteins
post_translational_modification
PTM: May be negatively regulated by phosphorylation. {ECO:0000250|UniProtKB:Q9JMC8}.
uniprot
proteins
pubmed
10603000
uniprot
proteins
pubmed
10783258
uniprot
proteins
pubmed
14521927
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
22006950
uniprot
proteins
pubmed
23664528
uniprot
proteins
sequence_length
900
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22006950}. Cell junction, tight junction {ECO:0000269|PubMed:22006950}. Note=Accumulates along apical cell-cell boundaries and is also detected in the cytoplasm in a punctate manner. {ECO:0000269|PubMed:22006950}.
uniprot
proteins