Ankrd13a
entrez
68420
canonical
uniprot
Q80UP5
canonical
ensembl
ENSMUSG00000041870
resolver
ensp
ENSMUSP00000099638
resolver
enst
ENSMUST00000102578
resolver
genesymbol
Ankrd13a
resolver
genesymbol_syn
Ankrd13
resolver
uniprot
Q2VPQ7
resolver
uniprot
Q6P7F2
resolver
uniprot_entry
AN13A_MOUSE
resolver
uniprot_sec
Q2VPQ7
resolver
uniprot_sec
Q6P7F2
resolver
amino_acid_sequence
MSSARDTSSRFPLHLLVWNNDYEQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSFIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITRIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGDLATECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTADESQGVEGTPAEAVSEATNFEVDQSVFEIPESYHIQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHTHSYEAQYERAIQESLLTNMEGRCPGGLSESSRFDSDLQLAMELSAKELAERELRLQEEEAELQQVLQLSLTEK
uniprot
proteins
function
FUNCTION: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
67177
uniprot
proteins
post_translational_modification
PTM: Monoubiquitinated, inhibits interaction with ubiquitinated EGFR. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
588
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane. Late endosome. Note=Interaction with EGFR may enhance association with the cell membrane. {ECO:0000250}.
uniprot
proteins