MIER1
entrez
57708
canonical
uniprot
Q8N108
canonical
ensembl
ENSG00000198160
resolver
ensp
ENSP00000347514
resolver
ensp
ENSP00000348253
resolver
ensp
ENSP00000350321
resolver
ensp
ENSP00000360051
resolver
ensp
ENSP00000360053
resolver
ensp
ENSP00000360055
resolver
ensp
ENSP00000360057
resolver
ensp
ENSP00000383820
resolver
ensp
ENSP00000383821
resolver
genesymbol
MIER1
resolver
genesymbol_syn
KIAA1610
resolver
hgnc
HGNC:29657
resolver
uniprot
C9JFD4
resolver
uniprot
Q08AE0
resolver
uniprot
Q32NC4
resolver
uniprot
Q5T104
resolver
uniprot
Q5TAD1
resolver
uniprot
Q5TAD2
resolver
uniprot
Q5TAD4
resolver
uniprot
Q5TAD5
resolver
uniprot
Q6AHY8
resolver
uniprot
Q86TB4
resolver
uniprot
Q8N156
resolver
uniprot
Q8N161
resolver
uniprot
Q8NC37
resolver
uniprot
Q8NES4
resolver
uniprot
Q8NES5
resolver
uniprot
Q8NES6
resolver
uniprot
Q8WWG2
resolver
uniprot
Q9HCG2
resolver
uniprot_entry
MIER1_HUMAN
resolver
uniprot_sec
C9JFD4
resolver
uniprot_sec
Q08AE0
resolver
uniprot_sec
Q32NC4
resolver
uniprot_sec
Q5T104
resolver
uniprot_sec
Q5TAD1
resolver
uniprot_sec
Q5TAD2
resolver
uniprot_sec
Q5TAD4
resolver
uniprot_sec
Q5TAD5
resolver
uniprot_sec
Q6AHY8
resolver
uniprot_sec
Q86TB4
resolver
uniprot_sec
Q8N156
resolver
uniprot_sec
Q8N161
resolver
uniprot_sec
Q8NC37
resolver
uniprot_sec
Q8NES4
resolver
uniprot_sec
Q8NES5
resolver
uniprot_sec
Q8NES6
resolver
uniprot_sec
Q8WWG2
resolver
uniprot_sec
Q9HCG2
resolver
amino_acid_sequence
MAEPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDAQEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEKVYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKEDGTVSTANQNGVSSNGPGEILNKEEVKVEGLHINGPTGGNKKPLHADMDTNGYETDNLTTDPKLAHMTARNENDFDEKSERPAKRRRVNSNGKESPGSSEFFQEAVSHGKFEELENTDD
uniprot
proteins
function
FUNCTION: Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing. {ECO:0000269|PubMed:12482978}.
uniprot
proteins
mass_dalton
57983
uniprot
proteins
mutagenesis
MUTAGEN 214; /note="W->A: Loss of transcriptional repression and HDAC1 recruitment activity."; /evidence="ECO:0000269|PubMed:12482978"; MUTAGEN 227..228; /note="FL->AA: Loss of transcriptional repression and HDAC1 recruitment activity."; /evidence="ECO:0000269|PubMed:12482978
uniprot
proteins
pubmed
10997877
uniprot
proteins
pubmed
12242014
uniprot
proteins
pubmed
12482978
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19061646
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
9813250
uniprot
proteins
sequence_length
512
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 3]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm.; SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm.; SUBCELLULAR LOCATION: [Isoform 6]: Cytoplasm.
uniprot
proteins