KLF13
entrez
51621
canonical
uniprot
Q9Y2Y9
canonical
ensembl
ENSG00000169926
resolver
ensembl
ENSG00000275746
resolver
ensp
ENSP00000302456
resolver
ensp
ENSP00000484904
resolver
enst
ENST00000307145
resolver
enst
ENST00000621843
resolver
genesymbol
KLF13
resolver
genesymbol_syn
BTEB3
resolver
genesymbol_syn
NSLP1
resolver
hgnc
HGNC:13672
resolver
uniprot
Q9Y356
resolver
uniprot
X5DNR2
resolver
uniprot_entry
KLF13_HUMAN
resolver
uniprot_entry
X5DNR2_HUMAN
resolver
uniprot_sec
Q9Y356
resolver
amino_acid_sequence
MAAAAYVDHFAAECLVSMSSRAVVHGPREGPESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAAAPPSPAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRHANFHPGMLQRRGGGSRTGSLSDYSRSDASSPTISPASSP
uniprot
proteins
function
FUNCTION: Transcription factor that activates expression from GC-rich minimal promoter regions, including genes in the cells of the erythroid lineage (By similarity). Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1 (PubMed:11477107). Activates RANTES and CCL5 expression in T-cells (PubMed:17513757). {ECO:0000250|UniProtKB:Q9JJZ6, ECO:0000269|PubMed:11477107, ECO:0000269|PubMed:17513757}.
uniprot
proteins
mass_dalton
31180
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PRP4K; phosphorylation regulates its transcriptional modulator activity. {ECO:0000269|PubMed:17513757}.
uniprot
proteins
protein_family
Sp1 C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
10023774
uniprot
proteins
pubmed
10415854
uniprot
proteins
pubmed
11477107
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17513757
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
288
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17513757}.
uniprot
proteins