SEPTIN1
entrez
1731
canonical
uniprot
Q8WYJ6
canonical
ensembl
ENSG00000180096
resolver
ensp
ENSP00000324511
resolver
ensp
ENSP00000498586
resolver
enst
ENST00000321367
resolver
genesymbol
SEPTIN1
resolver
genesymbol_syn
DIFF6
resolver
genesymbol_syn
PNUTL3
resolver
genesymbol_syn
SEPT1
resolver
hgnc
HGNC:2879
resolver
uniprot
B4DVE6
resolver
uniprot
J3KNL2
resolver
uniprot
Q658T1
resolver
uniprot
Q8NEZ1
resolver
uniprot
Q96EL4
resolver
uniprot
Q9H285
resolver
uniprot_entry
J3KNL2_HUMAN
resolver
uniprot_entry
SEPT1_HUMAN
resolver
uniprot_sec
B4DVE6
resolver
uniprot_sec
Q658T1
resolver
uniprot_sec
Q8NEZ1
resolver
uniprot_sec
Q96EL4
resolver
uniprot_sec
Q9H285
resolver
amino_acid_sequence
MAGGVMDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASARLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQSDAL
uniprot
proteins
function
FUNCTION: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}.
uniprot
proteins
mass_dalton
42386
uniprot
proteins
mutagenesis
MUTAGEN 24; /note="S->A: No effect on phosphorylation."; /evidence="ECO:0000269|PubMed:16179162"; MUTAGEN 211; /note="S->A: No effect on phosphorylation."; /evidence="ECO:0000269|PubMed:16179162"; MUTAGEN 253; /note="S->A: Great reduction in phosphorylation."; /evidence="ECO:0000269|PubMed:16179162"; MUTAGEN 312; /note="S->A: Great reduction in phosphorylation."; /evidence="ECO:0000269|PubMed:16179162"; MUTAGEN 317; /note="S->A: No effect on phosphorylation."; /evidence="ECO:0000269|PubMed:16179162"; MUTAGEN 320; /note="S->A: Great reduction in phosphorylation."; /evidence="ECO:0000269|PubMed:16179162
uniprot
proteins
protein_family
Septin GTPase family
uniprot
proteins
protein_family
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
uniprot
proteins
pubmed
12747765
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15915442
uniprot
proteins
pubmed
16179162
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
19799413
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
372
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
uniprot
proteins