Mppe1
entrez
225651
canonical
uniprot
Q80XL7
canonical
ensembl
ENSMUSG00000062526
resolver
ensp
ENSMUSP00000072808
resolver
ensp
ENSMUSP00000293082
resolver
ensp
ENSMUSP00000293086
resolver
ensp
ENSMUSP00000293088
resolver
ensp
ENSMUSP00000293091
resolver
ensp
ENSMUSP00000293110
resolver
ensp
ENSMUSP00000293122
resolver
genesymbol
Mppe1
resolver
genesymbol_syn
Pgap5
resolver
uniprot
Q3T9I6
resolver
uniprot
Q3TYP9
resolver
uniprot
Q3U4F5
resolver
uniprot
Q8BLU5
resolver
uniprot_entry
MPPE1_MOUSE
resolver
uniprot_sec
Q3T9I6
resolver
uniprot_sec
Q3TYP9
resolver
uniprot_sec
Q3U4F5
resolver
uniprot_sec
Q8BLU5
resolver
amino_acid_sequence
MALVRWGLKRQNFHPLRRRRRALLLKLTVVIISVLLFCEYFIYYLVLFRCHWPEVKTLAHGGRQEPVLKAMFLADTHLLGEIRGHWLDKLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSSDQAWADDVQRFQRMFRHDSHVQLKVVIGNHDVGFHYQMSKYRIKRFEKVFGSERLLSLKGVNFVMVNSVAMEGDGCIICSEEEAELREISRKLNCSQEVPGSSQCDREPEPRLPLSAPVLLQHYPLYRASDANCSGEDAAPPEERNVPFEEKYDVLSREASQKLLWWLRPRLVLSGHTHSACEVLHPGGAPEVSVPSFSWRNRNNPSFIMGSLTSRDYALSKCYLPFEDTVLTMYGAAAGFLMILILVHFEHLPSPFLCGWKLCRLHMRR
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Metallophosphoesterase that catalyzes the removal of a side-chain ethanolamine-phosphate (EtNP) from the second mannose of the GPI-anchor protein intermediate. Participates in the glycan remodeling steps of GPI-anchor maturation to allow an efficient transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. {ECO:0000250|UniProtKB:Q53F39}.
uniprot
proteins
mass_dalton
46012
uniprot
proteins
protein_family
MPPE1 family
uniprot
proteins
protein_family
Metallophosphoesterase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
396
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q53F39}; Multi-pass membrane protein {ECO:0000255}. Note=Also localizes to endoplasmic reticulum exit site. {ECO:0000250|UniProtKB:Q53F39}.
uniprot
proteins
transmembrane_region
TRANSMEM 28..48; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 356..376; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins