Mturn
entrez
68235
canonical
uniprot
Q8CGA4
canonical
ensembl
ENSMUSG00000038065
resolver
ensp
ENSMUSP00000140358
resolver
ensp
ENSMUSP00000140586
resolver
enst
ENSMUST00000187701
resolver
enst
ENSMUST00000190641
resolver
genesymbol
Mturn
resolver
uniprot
A0A087WQV4
resolver
uniprot_entry
A0A087WQV4_MOUSE
resolver
uniprot_entry
MTURN_MOUSE
resolver
amino_acid_sequence
MDFQQLADVAEKWCSSTPFELIAAEETERRMDFYADPGVSFYVLCPDNGCGDSFHVWSESEDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ
uniprot
proteins
function
FUNCTION: Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression (PubMed:24681962). Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser- 536' (By similarity). May be involved in early neuronal development (By similarity). {ECO:0000250|UniProtKB:Q7ZX36, ECO:0000269|PubMed:24681962}.
uniprot
proteins
mass_dalton
14841
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Tyr-34 is essential for its ability to promote megakaryocyte differentiation. {ECO:0000250|UniProtKB:Q8N3F0}.
uniprot
proteins
protein_family
MTURN family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24095902
uniprot
proteins
pubmed
24681962
uniprot
proteins
sequence_length
131
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8N3F0}.
uniprot
proteins