PRKRIP1
entrez
79706
canonical
uniprot
Q9H875
canonical
ensembl
ENSG00000128563
resolver
ensp
ENSP00000381010
resolver
genesymbol
PRKRIP1
resolver
hgnc
HGNC:21894
resolver
uniprot
B4DGM2
resolver
uniprot
Q8NDM6
resolver
uniprot
Q96CF8
resolver
uniprot_entry
PKRI1_HUMAN
resolver
uniprot_sec
B4DGM2
resolver
uniprot_sec
Q8NDM6
resolver
uniprot_sec
Q96CF8
resolver
amino_acid_sequence
MASPAASSVRPPRPKKEPQTLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMSEWAPRPPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQEGPGQPKEQGSSSSAEASGTEEEEEVPSFTMGR
uniprot
proteins
function
FUNCTION: Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:30705154). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity). {ECO:0000250|UniProtKB:Q9CWV6, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:30705154}.
uniprot
proteins
mass_dalton
20997
uniprot
proteins
protein_family
PRKRIP1 family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
28502770
uniprot
proteins
pubmed
30705154
uniprot
proteins
sequence_length
184
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:30705154}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9CWV6}.
uniprot
proteins