Pithd1
entrez
66193
canonical
uniprot
Q8BWR2
canonical
ensembl
ENSMUSG00000028669
resolver
ensp
ENSMUSP00000101477
resolver
genesymbol
Pithd1
resolver
genesymbol_syn
Trp26
resolver
uniprot
Q8BMZ1
resolver
uniprot_entry
PITH1_MOUSE
resolver
uniprot_sec
Q8BMZ1
resolver
amino_acid_sequence
MSHGHSHGGGGCRCAAEREEPPEQRGLAYGLYLRIDLERLQCLNESREGSGRGVFKPWEERTDRSKFVESDADEELLFNIPFTGNVKLKGVIIMGEDDDSHPSEMRLYKNIPQMSFDDTEREPEQTFSLNRDITGELEYATKISRFSNVYHLSIHISKNFGADTTKIFYIGLRGEWTELRRHEVTICNYEASANPADHRVHQVTPQTHFIS
uniprot
proteins
function
FUNCTION: Promotes megakaryocyte differentiation by up-regulating RUNX1 expression (PubMed:25134913). Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (By similarity). {ECO:0000250|UniProtKB:Q9GZP4, ECO:0000269|PubMed:25134913}.
uniprot
proteins
mass_dalton
24192
uniprot
proteins
protein_family
PITHD1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25134913
uniprot
proteins
sequence_length
211
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9GZP4}.
uniprot
proteins