Rgs8
entrez
54297
canonical
uniprot
P49804
canonical
ensembl
ENSRNOG00000002369
resolver
ensembl
ENSRNOG00055018466
resolver
ensembl
ENSRNOG00060014310
resolver
ensembl
ENSRNOG00065024937
resolver
ensp
ENSRNOP00000073985
resolver
ensp
ENSRNOP00000090756
resolver
ensp
ENSRNOP00055025336
resolver
ensp
ENSRNOP00060019538
resolver
ensp
ENSRNOP00065035085
resolver
enst
ENSRNOT00000083366
resolver
enst
ENSRNOT00000118774
resolver
enst
ENSRNOT00055031381
resolver
enst
ENSRNOT00060024492
resolver
enst
ENSRNOT00065042874
resolver
genesymbol
Rgs8
resolver
uniprot
A0A0G2K6Y1
resolver
uniprot_entry
A0A0G2K6Y1_RAT
resolver
uniprot_entry
RGS8_RAT
resolver
amino_acid_sequence
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPREVNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
uniprot
proteins
function
FUNCTION: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling. {ECO:0000269|PubMed:19609226, ECO:0000269|PubMed:9394004}.
uniprot
proteins
mass_dalton
20949
uniprot
proteins
pubmed
12880183
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19609226
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8548815
uniprot
proteins
pubmed
9394004
uniprot
proteins
sequence_length
180
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12880183}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Membrane {ECO:0000269|PubMed:9394004}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Perikaryon {ECO:0000269|PubMed:12880183}. Cell projection, dendrite {ECO:0000269|PubMed:12880183}. Nucleus {ECO:0000269|PubMed:12880183}. Note=Detected in Purkinje cell soma and dendrites. Associated with Purkinje cell membranes. Not detected in Purkinje cell nuclei. Detected in the nucleus after heterologous expression. Recruited to the cell membrane in the presence of GNAO1. {ECO:0000269|PubMed:12880183}.
uniprot
proteins