Mpc2
entrez
70456
canonical
uniprot
Q9D023
canonical
ensembl
ENSMUSG00000026568
resolver
ensp
ENSMUSP00000027853
resolver
enst
ENSMUST00000027853
resolver
genesymbol
Mpc2
resolver
genesymbol_syn
Brp44
resolver
uniprot
Q3UA44
resolver
uniprot_entry
MPC2_MOUSE
resolver
uniprot_sec
Q3UA44
resolver
amino_acid_sequence
MAAAGARGLRATYHRLMDKVELLLPKKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSTVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGSAGASQLFRIWRYNQELKSKGIQ
uniprot
proteins
function
FUNCTION: Mediates the uptake of pyruvate into mitochondria to maintain the balance between glycolysis and oxidative phosphorylation (PubMed:22628554). Plays an essential role in cellular metabolism (By similarity). {ECO:0000250|UniProtKB:O95563, ECO:0000269|PubMed:22628554}.
uniprot
proteins
mass_dalton
14286
uniprot
proteins
protein_family
Mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22628554
uniprot
proteins
pubmed
23576753
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:22628554}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O95563}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..61; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:O95563"; TRANSMEM 70..90; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:O95563"; TRANSMEM 94..115; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:O95563
uniprot
proteins