Gss
entrez
14854
canonical
uniprot
P51855
canonical
ensembl
ENSMUSG00000027610
resolver
ensp
ENSMUSP00000078630
resolver
ensp
ENSMUSP00000135319
resolver
ensp
ENSMUSP00000295885
resolver
enst
ENSMUST00000079691
resolver
enst
ENSMUST00000130881
resolver
genesymbol
Gss
resolver
uniprot
H3BKB0
resolver
uniprot
Q3UEE2
resolver
uniprot
Q541E2
resolver
uniprot_entry
GSHB_MOUSE
resolver
uniprot_entry
H3BKB0_MOUSE
resolver
uniprot_entry
Q3UEE2_MOUSE
resolver
uniprot_entry
Q541E2_MOUSE
resolver
amino_acid_sequence
MATSWGSILQDEKQLEELAKQAIDRALAEGVLLRSAQHPSSSDVVTYAPFTLFPSPVPSALLEQAYAVQMDFNILVDAVSQNPAFLEQTLSSTIKKDDYTARLFDIYKQVLKEGIAQTVFLGLNRSDYMFQCGADGSKALKQIEINTISASFGGLASRTPAVHRHVLNVLNKTKEASKILSNNPSKGLALGIAKAWELYGSANAVVLLIAQEKERNIFDQRAVENELLDRKIHVIRGRFEDVSERGSLDQNRRLFMDDQEVAVVYFRDGYMPSQYNSQNWEARLMLERSRAAKCPDIAIQLAGTKKVQQELSRVGLLEALLPGQPEAVARLRATFAGLYSLDMGEEGDQAIAEALAAPSHFVLKPQREGGGNNLYGEEMVQALEQLKDSEERASYILMEKIEPEPFRNCLLRPGSPAQVVQCISELGIFGVYVRQGTTLVMNKHVGHLLRTKAVEHADGGVAAGVAVLDNPYPV
uniprot
proteins
ec_number
6.3.2.3
uniprot
proteins
function
FUNCTION: Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes. Participates in ophthalmate biosynthesis in hepatocytes (PubMed:16608839). {ECO:0000250|UniProtKB:P48637, ECO:0000269|PubMed:16608839}.
uniprot
proteins
mass_dalton
52247
uniprot
proteins
pathway_participation
PATHWAY: Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2. {ECO:0000250|UniProtKB:P48637}.
uniprot
proteins
protein_family
Eukaryotic GSH synthase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16608839
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8660701
uniprot
proteins
sequence_length
474
uniprot
proteins