Lilrb3a
entrez
683463
canonical
uniprot
C0HJX2
canonical
ensembl
ENSRNOG00000058422
resolver
ensembl
ENSRNOG00060029830
resolver
ensp
ENSRNOP00000075528
resolver
ensp
ENSRNOP00060043119
resolver
enst
ENSRNOT00060051858
resolver
genesymbol
Lilrb3a
resolver
genesymbol
Lilrb3b
resolver
uniprot
C0HJX3
resolver
uniprot_entry
LRB3A_RAT
resolver
uniprot_entry
LRB3B_RAT
resolver
amino_acid_sequence
MTFTFTALLCLGLTLGLWIPVLTGSLPKPILRVQPDSVVSMGTTVTFICEETIGAKQSYLYRNGNLQRRVPKNNQKPTNKTEFLFLNVGHQNAGQYHCSYKSQGKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSHYGHTLILTVEGPQKLSWRQDPQCNYYTENCHVLFYVGPLTSNQRWIFRCYSYETNTPQVWSAPSEPVEILVSGKLQKPTIKAEPGSVIHSGKAMIIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKLFIRPVTQGHAGDYRCYYYSSAGWSEPSDTLELVVTGIYNYHPLMLSGPPSPVVPEGGNVTLHCTSHRYYDKFILIKEDQKFSSSLDTKYISSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSEPSNLLKILITGQLHHVLFLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLLSFASAPVELIVSGPIRTSDLPPTMSIPPDGLQRYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ
uniprot
proteins
function
FUNCTION: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). {ECO:0000250|UniProtKB:P97484}.
uniprot
proteins
function
FUNCTION: May act as receptor for class I MHC antigens. Becomes activated upon coligation with immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). {ECO:0000250|UniProtKB:P97484}.
uniprot
proteins
mass_dalton
82704
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-697 and Tyr-727 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2. {ECO:0000250|UniProtKB:P97484}.
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
744
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P97484}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 544..564; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins