Hsd17b11
entrez
114664
canonical
uniprot
Q9EQ06
canonical
ensembl
ENSMUSG00000029311
resolver
ensp
ENSMUSP00000031251
resolver
genesymbol
Hsd17b11
resolver
genesymbol_syn
Dhrs8
resolver
genesymbol_syn
Pan1b
resolver
uniprot
Q3U2P6
resolver
uniprot
Q8BR33
resolver
uniprot
Q8C7S0
resolver
uniprot_entry
DHB11_MOUSE
resolver
uniprot_sec
Q3U2P6
resolver
uniprot_sec
Q8BR33
resolver
uniprot_sec
Q8C7S0
resolver
amino_acid_sequence
MKYLLDLILLLPLLIVFSIESLVKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQAHPFVVDCSQREEIYSAAKKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGRTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTEKQMIFVPSSIALLTVLERIVPERFLQVLKHRINVKFDAVVGYKDK
uniprot
proteins
ec_number
1.1.1.62
uniprot
proteins
function
FUNCTION: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
uniprot
proteins
mass_dalton
32881
uniprot
proteins
protein_family
17-beta-HSD 3 subfamily
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
11165019
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18359291
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000305|PubMed:18359291}. Lipid droplet {ECO:0000269|PubMed:18359291}. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation. {ECO:0000269|PubMed:18359291}.
uniprot
proteins