Smad9
entrez
55994
canonical
uniprot
Q9JIW5
canonical
ensembl
ENSMUSG00000027796
resolver
ensp
ENSMUSP00000029371
resolver
enst
ENSMUST00000029371
resolver
genesymbol
Smad9
resolver
genesymbol_syn
Madh8
resolver
genesymbol_syn
Madh9
resolver
genesymbol_syn
Smad8
resolver
uniprot
Q3UVC6
resolver
uniprot
Q8CFF9
resolver
uniprot_entry
Q3UVC6_MOUSE
resolver
uniprot_entry
SMAD9_MOUSE
resolver
uniprot_sec
Q8CFF9
resolver
amino_acid_sequence
MHPSTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQSLCPAPPSSPGHVFPQSPCPTSYPHSPGSPSESDSPYQHSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
uniprot
proteins
function
FUNCTION: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.
uniprot
proteins
mass_dalton
48636
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase and activin type I receptor-like kinases (ALK-2, ALK-3 and ALK-6).
uniprot
proteins
protein_family
Dwarfin/SMAD family
uniprot
proteins
pubmed
10814522
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
uniprot
proteins