Cnst
entrez
226744
canonical
uniprot
Q8CBC4
canonical
ensembl
ENSMUSG00000038949
resolver
ensp
ENSMUSP00000048205
resolver
ensp
ENSMUSP00000316760
resolver
genesymbol
Cnst
resolver
uniprot
Q8BFS5
resolver
uniprot
Q8K053
resolver
uniprot_entry
CNST_MOUSE
resolver
uniprot_sec
Q8BFS5
resolver
uniprot_sec
Q8K053
resolver
amino_acid_sequence
MDDSDPPTYSLQIEPQDGCHPGDSVERRVTRLPSVSDENENQLAGDGPAGLTTSEGAMGRATVSEQDSLNNNESFPSSCEAAPTENAENTPSEGPKDDPPSLGQDQKLPAKRSPRAKKSSPKSAPPGDAVPVMQTQNATSQAAGEEEAAGVNANDPPKAPALQPLFSLIRGEVAQMDSRALPLFLHQVAETYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKAVQPRTVTPLRNSEKGFNGEDFEQLAKICTTHQDPLLSKLKTAPVEPSPERKSLARAIMSEEAVGTEAAAKEPEIETCPSTDPSGDRHEEEPQESSPGCHQMEWQTASPELPGTAGKDHTEELPSSTNATLDLHTQSLETAGSRSGPAAASNACKDSSCVPAPPTEDHCGVARDPKVAPPSESVAEQKLSTGDDGALPGLISEGKYSQAHRKELCLPLQDAFEALPRDQPHSSEVAEPRQPDVTASDGKSAQSQAGLETGPESALCGDRKACDVSTLCLEVCMAPEERRDSEDRVSKETEDYLHSLLERCLKDAEDSLSYEDIQDDDSDLLQDLSPEEASYSLQEDLPPDESTLSLDDLAKKIEIAEAIPAEGLVSILKKRNDTVGSHPAQMQQKPAKRRVRFQEIDDNLEQDEVGGGSCILLILLCIATVFLSVGGTALYCTLGNIESPVCTDFADNVDFYYTKLLQGVAGLKHWVYLS
uniprot
proteins
function
FUNCTION: Required for targeting of connexins to the plasma membrane. {ECO:0000250}.
uniprot
proteins
mass_dalton
76866
uniprot
proteins
mutagenesis
MUTAGEN 558..562; /note="DSDLL->NSDAA: Does not affect binding to connexins but results in their intracellular accumulation."; /evidence="ECO:0000269|PubMed:19864490
uniprot
proteins
protein_family
CNST family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19864490
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
711
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Note=Located predominantly in the trans-Golgi network. Probably trafficks between the trans-Golgi network and the cell membrane via the secretory pathway (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 651..671; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins