Frmd4a
entrez
209630
canonical
uniprot
Q8BIE6
canonical
ensembl
ENSMUSG00000026657
resolver
ensp
ENSMUSP00000075172
resolver
ensp
ENSMUSP00000089079
resolver
ensp
ENSMUSP00000134788
resolver
ensp
ENSMUSP00000134803
resolver
enst
ENSMUST00000176828
resolver
enst
ENSMUST00000177457
resolver
genesymbol
Frmd4a
resolver
genesymbol_syn
Frmd4
resolver
genesymbol_syn
Kiaa1294
resolver
uniprot
B1AXK1
resolver
uniprot
B1AXK2
resolver
uniprot
H3BIZ7
resolver
uniprot
H3BJ11
resolver
uniprot
Q3TB04
resolver
uniprot
Q6PDJ4
resolver
uniprot
Q8CHA6
resolver
uniprot_entry
FRM4A_MOUSE
resolver
uniprot_entry
H3BIZ7_MOUSE
resolver
uniprot_entry
H3BJ11_MOUSE
resolver
uniprot_entry
Q3TB04_MOUSE
resolver
uniprot_sec
B1AXK1
resolver
uniprot_sec
B1AXK2
resolver
uniprot_sec
Q6PDJ4
resolver
uniprot_sec
Q8CHA6
resolver
amino_acid_sequence
MTEGRRCQVHLLDDRKLELLVQPKLLAKELLDLVASHFNLKEKEYFGIAFTDETGHLNWLQLDRRVLEHDFPKKSGPVVLYFCVRFYIESISYLKDNATIELFFLNAKSCIYKELIDVDSEVVFELASYILQEAKGDFSSNEVVRSDLKKLPALPTQALKEHPSLAYCEDRVIEYYKKLNGQTRGQAIVNYMSIVESLPTYGVHYYAVKDKQGIPWWLGLSYKGIFQYDYHDKVKPRKIFQWRQLENLYFREKKFSVEVHDPRRASVTRRTFGHSGIAVHTWYACPALIKSIWAMAISQHQFYLDRKQSKSKIHAARSLSEIAIDLTETGTLKTSKLANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKRLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLVIDDGNIASEDSSLSDALVLEDEDSQVTSTISPLQSPHKGLPPRPPSSHNRPPPPQSLEGLRQLHYHRTDYDKSPLKPKMWSESSLDEPYEKVKKRSSHGHSSSHKRFPSTGSCTEAGVSSSLQNSPIRSLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYTPRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARSGAASTGGGVYLHSQSQPSSQYRIKEYPLYIEGSATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGDEGDAGRLTPSRSQILRTPSLGRDGAHDKGSGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGATPPSSPHHILTWQTGEATENSPIMDGSESPTHQSTDE
uniprot
proteins
function
FUNCTION: Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (PubMed:20080746). Plays a redundant role with FRMD4B in epithelial polarization (PubMed:20080746). May regulate MAPT secretion by activating ARF6-signaling (By similarity). {ECO:0000250|UniProtKB:Q9P2Q2, ECO:0000269|PubMed:20080746}.
uniprot
proteins
mass_dalton
113879
uniprot
proteins
pubmed
12465718
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20080746
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1020
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, adherens junction {ECO:0000269|PubMed:20080746}. Cell junction, tight junction {ECO:0000269|PubMed:20080746}. Note=Colocalized with CYTH1 at adherens junction and tight junction (PubMed:20080746). Colocalized with PARD3 during the process of epithelial polarization (PubMed:20080746). {ECO:0000269|PubMed:20080746}.
uniprot
proteins