Acad11
entrez
102632
canonical
uniprot
Q80XL6
canonical
ensembl
ENSMUSG00000090150
resolver
ensp
ENSMUSP00000043424
resolver
enst
ENSMUST00000047799
resolver
genesymbol
Acad11
resolver
uniprot
A0A0R4J0I6
resolver
uniprot
Q8BK19
resolver
uniprot_entry
A0A0R4J0I6_MOUSE
resolver
uniprot_entry
ACD11_MOUSE
resolver
uniprot_sec
Q8BK19
resolver
amino_acid_sequence
METDVTSDTVEVLPQHKFDLRSLEAYLNQHLPGFGSDSRAVLTVTQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKIQKALFSIGFPVAKPLLYCRDASVIGTEFYVMEHVQGRIFRDFSIPGVSSAERAAIYVSVAETLAWLHSLDIRSLKLDKYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMKNLPDSDSEECLVHGDFKLDNIVFHPKECRVIAVLDWELSTFGHPLTDLAHLSLFYYWPRTLPMINRGSHIPENTGIPLMEELISIYCHRRGIDPNLPNWNFFMALSFFKLAGISQGVYRRYLMGNNSSEDSFLTANTVQPLAETGLQLSKRTLRTTPPQADAKSQLFAQSRRGQEVLTRVKQFMKQHVFPAEKEVAEYYAQSGNSAEKWGHPLVIEKLKEMAKAEGLWNLFLPAVSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKKQWLEPLLRGDITSVFCMTEPNVSSSDATNIECTIQRDGGGYIVNGKKWWSSGAGNPKCKIAIVLGRTESPSASRHRQHSMILVPMDTPGVELIRPLSVFGYMDNMHGGHWEVHFNHVRVPASNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERILQIMCDRAVQREAFKKKLYEHEVVAHWIAKSRIAIEEIRLLTLKAAHSIDTLGSASARKEIAMIKVAAPKAVCKIADWAIQVHGGAGVSQDYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARRLTARM
uniprot
proteins
ec_number
1.3.8.8
uniprot
proteins
function
FUNCTION: Participates in fatty acid beta-oxidation (FAO) and energy production in the central nervous system (CNS), and to a lesser extent in the liver. Catalyzes the first step in FAO, which consists in the proR-proR stereospecific alpha,beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, with maximal activity towards saturated docosanoyl-CoA (CoA 22:0) in both the cerebellum and the liver. Among the different mitochondrial acyl-CoA dehydrogenases, its FAO activity overlaps with that of ACADV and ACADL, but plays a primary role in tissues where it is the main long-chain ACAD expressed, such as the CNS, where together with ACAD9, they accommodate the full spectrum of long chain fatty acid substrates. {ECO:0000250|UniProtKB:Q709F0}.
uniprot
proteins
mass_dalton
87366
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid beta-oxidation. {ECO:0000250|UniProtKB:Q709F0}.
uniprot
proteins
protein_family
Acyl-CoA dehydrogenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17768142
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
779
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000269|PubMed:17768142}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q709F0}.
uniprot
proteins