Dpm2
entrez
13481
canonical
uniprot
Q9Z324
canonical
ensembl
ENSMUSG00000026810
resolver
ensp
ENSMUSP00000028151
resolver
enst
ENSMUST00000028151
resolver
genesymbol
Dpm2
resolver
uniprot
Q545R7
resolver
uniprot_entry
DPM2_MOUSE
resolver
uniprot_entry
Q545R7_MOUSE
resolver
amino_acid_sequence
MATGTDQAVGFGLVAVSLIIFTYYTTWVILLPFIDSQHVIHKYFLPRAYAVLLPLAAGLLLLLFVGLFITYVMLKSQKITKKAQ
uniprot
proteins
function
FUNCTION: Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the GPI-GNT complex. {ECO:0000250|UniProtKB:O94777}.
uniprot
proteins
mass_dalton
9376
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:O94777}.
uniprot
proteins
protein_family
DPM2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9724629
uniprot
proteins
sequence_length
84
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 49..69; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins