Lrrc4
entrez
192198
canonical
uniprot
Q99PH1
canonical
ensembl
ENSMUSG00000049939
resolver
ensp
ENSMUSP00000062158
resolver
enst
ENSMUST00000062304
resolver
genesymbol
Lrrc4
resolver
uniprot
Q149E5
resolver
uniprot
Q8VI35
resolver
uniprot_entry
LRRC4_MOUSE
resolver
uniprot_sec
Q149E5
resolver
uniprot_sec
Q8VI35
resolver
amino_acid_sequence
MKLLWQVTVHHTWNAVLLPVVYLTAQVWILCAAIAAAASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWLREYIPTNSTCCGRCHAPMHMRGRYLVEVDQAAFQCSAPFIMDAPRDLNISEDRMAELKCRTPPMSSVKWLLPNGTVLSHASRHPRISVLNDGTLNFSRVLLIDTGVYTCMVTNVAGNSNASAYLNVSSAELNTPNFSFFTTVTVETTEISPEDITRKYKPVPTTSTGYQPAYTTSTTVLIQTTRVPKQVPVPSTDTTDKMQTSLDEVMKTTKIIIGCFVAVTLLAAAMLIVFYKLRKRHQQRSTVTAARTVEIIQVDEDIPAAAPAAATAAPSGVSGEGAVVLPTIHDHINYNTYKPAHGAHWTENSLGNSLHPTVTTISEPYIIQTHTKDKVQETQI
uniprot
proteins
function
FUNCTION: Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma. {ECO:0000269|PubMed:15967442, ECO:0000269|PubMed:16980967, ECO:0000269|PubMed:17785411}.
uniprot
proteins
mass_dalton
72619
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15967442
uniprot
proteins
pubmed
16980967
uniprot
proteins
pubmed
17785411
uniprot
proteins
pubmed
17973922
uniprot
proteins
sequence_length
652
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. Postsynaptic cell membrane {ECO:0000250}. Note=LRRC4 and DLG4 are interdependent for synaptic localization. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 527..547; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins