Dhx34
entrez
71723
canonical
uniprot
Q9DBV3
canonical
ensembl
ENSMUSG00000006019
resolver
ensp
ENSMUSP00000092410
resolver
ensp
ENSMUSP00000126915
resolver
ensp
ENSMUSP00000321011
resolver
ensp
ENSMUSP00000321013
resolver
ensp
ENSMUSP00000321018
resolver
enst
ENSMUST00000094816
resolver
enst
ENSMUST00000163968
resolver
genesymbol
Dhx34
resolver
genesymbol_syn
Ddx34
resolver
genesymbol_syn
Kiaa0134
resolver
uniprot
A0A0R4J217
resolver
uniprot
Q66JM5
resolver
uniprot_entry
A0A0R4J217_MOUSE
resolver
uniprot_entry
DHX34_MOUSE
resolver
uniprot_entry
Q66JM5_MOUSE
resolver
amino_acid_sequence
MPPPRTREGRGHRDRDHHRAPREEEAPEKWDWNCPETRCLLEDVFFRDEDYIRRGSEECQKFWAFFERLQRFQHLKTSQKKKKDPGMPKHGIAALADLPLTYDPRYRINLSILSPDTRGRHGPGRGLPPERVSEFRRALLHYLDFQQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSHVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYQVLIVDEVHERHLHNDFLLGVLQRLLPQRPDLKVILMSATINISLFSSYFSHAPVVQVPGRLFPITVVYQPQEADQTASKSEKLDPRPFLRVLEAIDNKYPPEERGDLLVFLSGMAEITTVLDAAQAYASLTQRWVVLPLHSALSVSDQDKVFDVAPAGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCYRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSMSVGDPRTFPFIEPPPPASVETAILYLQEQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLAEPVLTIAAALSVQSPFTRSAQSNLDCATARRPLESDQGDPFTLFNVFNAWVQVKSERSGNSRKWCRRRGVEEHRLYEMANLRRQFKELLEDHGLLSGAQVVAPGDSYSRLQQRRERRALHQLKRQHEEGGGRRRKVLRLQEDGCSSDEEDRKGSTSQRADSVDIQDVKFKLRHNLEQLQAAASSAQDLTRDQLALLKLVLGRGLYPQLAVPDAFNSGRKDSDQIFHTQAKQGTVLHPTCVFANSPEVLHTQGQEASGQEGSQDGRDQMSCKHQLLAFVSLLETNKPYLVNCVRIPALQSLLLFSRSIDTNGDCSRLVADGWLELQLADSESAVRLLATSLRLRAHWESALDRQLARQAQRRKLEQEEDVGSPAVSPQEVAALSRELLQFMAAKVPYRLRRLTGLEAQNLYVGPQTITTAPSLPGLFGNSTLSPHPTKGGYAVSDYLTYNCLTSDTDLYSDCLRSFWTCPHCGLHMPFTPLERIAHENTCPEAPGDDPGSEEAAPAPPQKTSALQRPYHCQVCGQDFLFTPTEVLRHRRQHV
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: Probable ATP-binding RNA helicase (By similarity). Required for nonsense-mediated decay (NMD) degradation of mRNA transcripts containing premature stop codons (By similarity). Promotes the phosphorylation of UPF1 along with its interaction with key NMD pathway proteins UPF2 and EIF4A3 (By similarity). Negatively regulates the nucleotide binding ability and ATP hydrolysis of the RUVBL1-RUVBL2 complex via induction of N-terminus conformation changes of the RUVBL2 subunits (By similarity). {ECO:0000250|UniProtKB:A2BIE5, ECO:0000250|UniProtKB:Q14147}.
uniprot
proteins
mass_dalton
128507
uniprot
proteins
protein_family
DEAD box helicase family
uniprot
proteins
protein_family
DEAH subfamily
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1145
uniprot
proteins