Akr1c2
entrez
291283
canonical
uniprot
Q6AYQ2
canonical
ensembl
ENSRNOG00000029844
resolver
ensp
ENSRNOP00000045355
resolver
ensp
ENSRNOP00000107623
resolver
enst
ENSRNOT00000051342
resolver
enst
ENSRNOT00000160073
resolver
genesymbol
Akr1c2
resolver
genesymbol
Akr1c21
resolver
genesymbol_syn
RAKg
resolver
uniprot
A0A387KBL1
resolver
uniprot
A0A8L2QM68
resolver
uniprot
A0ABK0LAS3
resolver
uniprot_entry
A0A387KBL1_RAT
resolver
uniprot_entry
A0A8L2QM68_RAT
resolver
uniprot_entry
A0ABK0LAS3_RAT
resolver
uniprot_entry
AK1CL_RAT
resolver
amino_acid_sequence
MNSKCHCVKLNDGHFIPVLGFGTAMPSELPKSKAKEVTKIAIDAGFHHFDSAFVYNTEDHVGEAIREKIANGTTRREDIFYTSKLWCTSLHPELVRSSLECSLKKLQLDYVDLYLIHFPMALKPGDENFPVDEHGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQMKLLDFCKTNGIILVAYGVLGTQRYNGWVDQNSPVLLNEPVLSSMAKKYNQTPALIALRHQLQRGIVVLNTSLKEERIKENMKLSPEDMKVLDDLNRNLRYIAGGIFEGHPNFPFLDEY
uniprot
proteins
ec_number
1.1.1.-
uniprot
proteins
ec_number
1.1.1.209
uniprot
proteins
function
FUNCTION: NADP-dependent 17-alpha-hydroxysteroid dehydrogenase that converts 5-alpha-androstane-3,17-dione into androsterone. Has lower 3-alpha-hydroxysteroid dehydrogenase activity. Has broad substrate specificity and acts on various 17-alpha-hydroxysteroids, 17-ketosteroids, 3-alpha hydroxysteroids and 3-ketosteroids. Reduction of keto groups is strictly stereoselective. Reduction of 17-ketosteroids yields only 17-alpha-hydroxysteroids. Likewise, reduction of 3-ketosteroids yields only 3-alpha-hydroxysteroids (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
36135
uniprot
proteins
protein_family
Aldo/keto reductase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
318
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins