Pycr1
entrez
209027
canonical
uniprot
Q922W5
canonical
ensembl
ENSMUSG00000025140
resolver
ensp
ENSMUSP00000026133
resolver
ensp
ENSMUSP00000131199
resolver
ensp
ENSMUSP00000185739
resolver
ensp
ENSMUSP00000333258
resolver
enst
ENSMUST00000026133
resolver
enst
ENSMUST00000170556
resolver
genesymbol
Pycr1
resolver
uniprot
Q3UTR5
resolver
uniprot_entry
P5CR1_MOUSE
resolver
uniprot_entry
Q3UTR5_MOUSE
resolver
amino_acid_sequence
MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDQATVSALRKIGVNLTPHNKETVRHSDVLFLAVKPHIIPFILDEIGANIEDRHIVVSCAAGVTINSIEKKLTAFQPAPKVIRCMTNTPVVVREGVTVYATGTHAQVEDGRLVEQLMGSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPSQLKDNVCSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQTMADQETISPAAIKKTVLDKVKLDSSAGASLSSDHVKPLP
uniprot
proteins
ec_number
1.5.1.2
uniprot
proteins
function
FUNCTION: Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress. {ECO:0000250|UniProtKB:P32322}.
uniprot
proteins
mass_dalton
32373
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.
uniprot
proteins
protein_family
Pyrroline-5-carboxylate reductase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19648921
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
309
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P32322}.
uniprot
proteins