P3h2
entrez
288016
canonical
uniprot
Q4KLM6
canonical
ensembl
ENSRNOG00000055751
resolver
ensembl
ENSRNOG00055004599
resolver
ensembl
ENSRNOG00060013050
resolver
ensp
ENSRNOP00000074673
resolver
ensp
ENSRNOP00055005446
resolver
ensp
ENSRNOP00060017621
resolver
enst
ENSRNOT00000089540
resolver
enst
ENSRNOT00055007285
resolver
enst
ENSRNOT00060022234
resolver
genesymbol
P3h2
resolver
genesymbol_syn
Leprel1
resolver
uniprot_entry
P3H2_RAT
resolver
amino_acid_sequence
MRESTWVSLLLLLLLPAPQRGGPQDGRGSPEPEPERGPLQPFDLLYASGVAAYYSGDYEGAVRDLEAALRSHRRLRDIRTRCARHCAARRPLAPPGAGPGAELPFFRAVLERARCSRSCQSQRLGGPASRHRVSEDVRSDFQRRVPYNYLQRAYIKLNQLDKAMEAAHTFFMANPEHMEMQQNIEDYKATARVEAPLVDREAKPHLESYNAGVKHYEADDFEAAIKYFEQALREYFNEDMVCRALCEGPQRFEEYEYLGSKGSLYEAIADHYMQVLVCQHECVRELATRPGRLSPIENFLPLHYDYLQFAYYRVGEYVKALECAKAYLMFHPDDQDVLDNVDFYESLLDDSTDPASIEAREDLTAFVKRHKLEAELIKSAAEGLGFSYSEPNYWISYGGRQDENRVPSGVNMDGAEVHGLSMGKKSPPKIGRDLREGGPLLYENITFVYNSEQLNGTQRVLLDNVLSEEQCRELHSVASGIMLVGDGYRGKTSPHTPNEKFEGATVLKALKFGYEGRVPLKSARLFYDISEKARKIVESYFMLNSTLYFSYTHMVCRTALSGQQDRRNDLSHPIHADNCLLDPEANECWKEPPAYTFRDYSALLYMNDDFEGGEFIFTEMDAKTVTASIKPKCGRMISFSSGGENPHGVKAVTRGQRCAVALWFTLDPLYRELERIQADEVIAILDQEQHGKHGLNINPKDEL
uniprot
proteins
ec_number
1.14.11.7
uniprot
proteins
function
FUNCTION: Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (PubMed:21757687). Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity). Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1. Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline. Has no activity on substrates that lack 4-hydroxyproline in the third position (By similarity). {ECO:0000250|UniProtKB:Q8CG71, ECO:0000250|UniProtKB:Q8IVL5, ECO:0000305|PubMed:21757687}.
uniprot
proteins
mass_dalton
79833
uniprot
proteins
protein_family
Leprecan family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21757687
uniprot
proteins
sequence_length
703
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8IVL5, ECO:0000255|PROSITE-ProRule:PRU10138}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:Q8IVL5}. Golgi apparatus {ECO:0000250|UniProtKB:Q8IVL5}.
uniprot
proteins