Tmem135
entrez
293098
canonical
uniprot
Q5U4F4
canonical
ensembl
ENSRNOG00000016815
resolver
ensembl
ENSRNOG00055019358
resolver
ensembl
ENSRNOG00060021135
resolver
ensembl
ENSRNOG00065028749
resolver
ensp
ENSRNOP00000022578
resolver
ensp
ENSRNOP00055026760
resolver
ensp
ENSRNOP00060030186
resolver
ensp
ENSRNOP00065040743
resolver
enst
ENSRNOT00000022578
resolver
enst
ENSRNOT00055033033
resolver
enst
ENSRNOT00060036675
resolver
enst
ENSRNOT00065049628
resolver
genesymbol
Tmem135
resolver
uniprot_entry
TM135_RAT
resolver
amino_acid_sequence
MAALSKSIPHNCYEIGHTWNPSCRVSFLQITWGALEESLRIYAPLYLIAAVLRKRKLEYYLYKLLPEILQSASFLTANGALYITFFCVLRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMANLATETLFRMGVARGTITTLRNGEVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIPTHSYSPETAYAKVEQKREKHRGTTRAMSLIALVRSLVDSICKHGPRHRCCKHYEDNCISYCIKGFIRMFSVGYLIQCCLRIPSAFRHLFTEPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRWIRNLDDELHAIVAGFLAGVSMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPQADTIIYSISTAICFHAAVMEVQNLRPSYWKFLLRLTKGRFALMNRKALDVFGTGASREFHNFIPRLDPRYTVVTPELPIDFS
uniprot
proteins
function
FUNCTION: Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission (By similarity). May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L (By similarity). May be involved in peroxisome organization (PubMed:17522052). {ECO:0000250|UniProtKB:Q9CYV5, ECO:0000269|PubMed:17522052}.
uniprot
proteins
mass_dalton
52359
uniprot
proteins
protein_family
TMEM135 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17522052
uniprot
proteins
sequence_length
458
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:Q9CYV5}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9CYV5}. Peroxisome membrane {ECO:0000305|PubMed:17522052}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 96..116; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 149..169; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 298..318; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 331..351; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 377..397; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins