Foxa3
entrez
25100
canonical
uniprot
P32183
canonical
genesymbol
Foxa3
resolver
genesymbol_syn
Hnf3g
resolver
genesymbol_syn
Tcf-3g
resolver
genesymbol_syn
Tcf3g
resolver
uniprot_entry
FOXA3_RAT
resolver
amino_acid_sequence
MLGSVKMEAHDLAEWSYYPEAGEVYSPVNPVPTMAPLNSYMSLNPLSSPYPPGGLQASPLPTGPLAPPAPTAPLGPTFPGLGAGSGTGGSASGYGAPGPGLVHGKEMAKGYRRPLTHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAKKGNSATSATRNGTVGSATSATTTAATAVTSPAQPQPTPPSEPEAQSGEDVGGLDCASPPSSAPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTSTPSKLDVGFGGYGAESGEPGVYYQSLYSRSLLNAS
uniprot
proteins
function
FUNCTION: Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis (By similarity). {ECO:0000250, ECO:0000269|PubMed:9369482}.
uniprot
proteins
mass_dalton
37652
uniprot
proteins
pubmed
1672118
uniprot
proteins
pubmed
8332212
uniprot
proteins
pubmed
9369482
uniprot
proteins
sequence_length
354
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins