St3gal6
entrez
54613
canonical
uniprot
Q8VIB3
canonical
ensembl
ENSMUSG00000022747
resolver
ensp
ENSMUSP00000109997
resolver
ensp
ENSMUSP00000109998
resolver
ensp
ENSMUSP00000115756
resolver
ensp
ENSMUSP00000322441
resolver
ensp
ENSMUSP00000322442
resolver
ensp
ENSMUSP00000322445
resolver
ensp
ENSMUSP00000322448
resolver
ensp
ENSMUSP00000322451
resolver
ensp
ENSMUSP00000322452
resolver
ensp
ENSMUSP00000322455
resolver
ensp
ENSMUSP00000362445
resolver
enst
ENSMUST00000114357
resolver
enst
ENSMUST00000114358
resolver
enst
ENSMUST00000137035
resolver
genesymbol
St3gal6
resolver
genesymbol_syn
Siat10
resolver
uniprot
Q3TRN3
resolver
uniprot
Q80UR7
resolver
uniprot
Q9WVG2
resolver
uniprot_entry
SIA10_MOUSE
resolver
uniprot_sec
Q3TRN3
resolver
uniprot_sec
Q80UR7
resolver
uniprot_sec
Q9WVG2
resolver
amino_acid_sequence
MKGYLVAIFLSSIFLYYVLYCILWGTNGYWFPAEEMRTRNNVNNCFKKPAFANLLRFPQLYPFLCRADFIKVAAMSGTNNFPLPYGIKTFETYFSSALSKLQSCDLFDEFDRVPCKRCVVVGNGGVLKNKTLGATIDSYDVIIRMNNGPVLGHEEEVGTRTTFRLFYPESVFSDSSHYDPNTTAVLVVFKPQDLRWLVEILLGKKINTQGFWKTPALKLIYKQYQIRILDPYITSEAAFQMLRFPRVFPKDQKPKHPTTGIIAITMAFHICSEVHLAGFKYNFYSPNSPLHYYGNATMSLMKQNAYHNLTAEQLFLNDIIKKKMVINLT
uniprot
proteins
ec_number
2.4.3.6
uniprot
proteins
function
FUNCTION: Transfers the sialyl residue from CMP-N-acetyl-beta-neuraminate to the terminal galactose residue on sugar chains of glycoproteins and glycolipids. Its alpha-2,3-sialyltransferase activity is specific toward type II glycan chains (Galbeta1-4GlcNAc) on glycoproteins and glycolipids such as neolactosides nLc4Cer and nLc6Cer, whose sialyl-products serve as precursors for the Lewis X antigen (By similarity). Critically involved in the synthesis of functional selectin ligands needed for neutrophil recruitment during inflammation and lymphocyte homing to the lymph nodes (PubMed:22700726). {ECO:0000250|UniProtKB:Q9Y274, ECO:0000269|PubMed:22700726}.
uniprot
proteins
mass_dalton
37854
uniprot
proteins
protein_family
Glycosyltransferase 29 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
22700726
uniprot
proteins
sequence_length
329
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..25; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins