Sertad1
entrez
55942
canonical
uniprot
Q9JL10
canonical
ensembl
ENSMUSG00000008384
resolver
ensp
ENSMUSP00000008528
resolver
enst
ENSMUST00000008528
resolver
genesymbol
Sertad1
resolver
genesymbol_syn
Sei1
resolver
uniprot
Q925E6
resolver
uniprot
Q9D888
resolver
uniprot_entry
SRTD1_MOUSE
resolver
uniprot_sec
Q925E6
resolver
uniprot_sec
Q9D888
resolver
amino_acid_sequence
MLSKGLKRKREEEETMEALSVDSCWLDPSHPAVAQTPPTVASSSLFDLSVVKLHHSLRQSEPDLRHLVLVVNTLRRIQASMEPAPVLPPEPIQPPAPSVADSLLASSDAGLSASMASLLEDLNHIEDLNQAPQPQADEGPPGRSIGGISPNLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDSELWLPASEGLKPGPENGPAKEEPPELDEAELDYLMDVLVGTQALERPPGPGR
uniprot
proteins
function
FUNCTION: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A. {ECO:0000269|PubMed:11331592}.
uniprot
proteins
mass_dalton
25136
uniprot
proteins
post_translational_modification
PTM: Polyubiquitinated, which promotes proteasomal degradation. {ECO:0000250}.
uniprot
proteins
pubmed
11331592
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
236
uniprot
proteins