SCAMP5
entrez
192683
canonical
uniprot
Q8TAC9
canonical
ensembl
ENSG00000198794
resolver
ensp
ENSP00000355387
resolver
ensp
ENSP00000406547
resolver
ensp
ENSP00000542321
resolver
ensp
ENSP00000582907
resolver
genesymbol
SCAMP5
resolver
hgnc
HGNC:30386
resolver
uniprot
A0A0A8K8F5
resolver
uniprot
B3KPJ7
resolver
uniprot
B7Z762
resolver
uniprot
D3DW71
resolver
uniprot
Q8N3M4
resolver
uniprot_entry
A0A0A8K8F5_HUMAN
resolver
uniprot_entry
SCAM5_HUMAN
resolver
uniprot_sec
B3KPJ7
resolver
uniprot_sec
B7Z762
resolver
uniprot_sec
D3DW71
resolver
uniprot_sec
Q8N3M4
resolver
amino_acid_sequence
MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM
uniprot
proteins
function
FUNCTION: Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway. {ECO:0000269|PubMed:19234194}.
uniprot
proteins
mass_dalton
26104
uniprot
proteins
protein_family
SCAMP family
uniprot
proteins
protein_family
SCAMP5 subfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15840657
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19234194
uniprot
proteins
pubmed
19240033
uniprot
proteins
sequence_length
235
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 103..125; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 149..169; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins