Grxcr1
entrez
433899
canonical
uniprot
Q50H32
canonical
ensembl
ENSMUSG00000068082
resolver
ensp
ENSMUSP00000092305
resolver
enst
ENSMUST00000094715
resolver
genesymbol
Grxcr1
resolver
genesymbol_syn
pi
resolver
uniprot
G3X9N2
resolver
uniprot_entry
G3X9N2_MOUSE
resolver
uniprot_entry
GRCR1_MOUSE
resolver
amino_acid_sequence
MLRRETKPESDRPRKVRFRIASSHSGRVLKEVYEDGQAPGSLDSECASICAIDGLSDSEGQQNGHIGSEDNEQEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCTC
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Grxcr1 are the cause of the pirouette (pi) phenotype which is characterized by vestibular defects and profound deafness with affected mice displaying abnormally thin and slightly shortened sterocilia. {ECO:0000269|PubMed:11276175, ECO:0000269|PubMed:20137774}.
uniprot
proteins
function
FUNCTION: May play a role in actin filament architecture in developing stereocilia of sensory cells. {ECO:0000269|PubMed:20137774}.
uniprot
proteins
mass_dalton
32402
uniprot
proteins
protein_family
GRXCR1 family
uniprot
proteins
pubmed
11276175
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20137774
uniprot
proteins
sequence_length
290
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, stereocilium {ECO:0000269|PubMed:20137774}. Cell projection, microvillus {ECO:0000269|PubMed:20137774}. Cell projection, kinocilium {ECO:0000269|PubMed:20137774}. Note=In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia.
uniprot
proteins