SAMSN1
entrez
64092
canonical
uniprot
Q9NSI8
canonical
ensembl
ENSG00000155307
resolver
ensp
ENSP00000285670
resolver
ensp
ENSP00000383411
resolver
ensp
ENSP00000480850
resolver
ensp
ENSP00000493867
resolver
ensp
ENSP00000541970
resolver
enst
ENST00000619120
resolver
enst
ENST00000647101
resolver
genesymbol
SAMSN1
resolver
genesymbol_syn
HACS1
resolver
hgnc
HGNC:10528
resolver
uniprot
A0A087WXA2
resolver
uniprot
A0A2R8Y4K8
resolver
uniprot
B3KWJ3
resolver
uniprot
F8WAA1
resolver
uniprot
Q8NFF7
resolver
uniprot
Q9C041
resolver
uniprot
S6FRS6
resolver
uniprot_entry
A0A087WXA2_HUMAN
resolver
uniprot_entry
A0A2R8Y4K8_HUMAN
resolver
uniprot_entry
S6FRS6_HUMAN
resolver
uniprot_entry
SAMN1_HUMAN
resolver
uniprot_sec
B3KWJ3
resolver
uniprot_sec
F8WAA1
resolver
uniprot_sec
Q8NFF7
resolver
uniprot_sec
Q9C041
resolver
amino_acid_sequence
MLKRKPSNVSEKEKHQKPKRSSSFGNFDRFRNNSLSKPDDSTEAHEGDPTNGSGEQSKTSNNGGGLGKKMRAISWTMKKKVGKKYIKALSEEKDEEDGENAHPYRNSDPVIGTHTEKVSLKASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDGPYSGPFCGRARVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKKIKANRRSNSKKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLEEEIIQEQENEPEPLSLSSDISLNKSQLDDCPRDSGCYISSGNSDNGKEDLESENLSDMVHKIIITEPSD
uniprot
proteins
function
FUNCTION: Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity). {ECO:0000250, ECO:0000269|PubMed:15381729}.
uniprot
proteins
mass_dalton
41708
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
11536050
uniprot
proteins
pubmed
11594764
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15381729
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19807924
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11594764}. Cytoplasm {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles (By similarity). {ECO:0000250}.
uniprot
proteins