Ereg
entrez
59325
canonical
uniprot
Q9Z0L5
canonical
ensembl
ENSRNOG00000002771
resolver
ensembl
ENSRNOG00055006392
resolver
ensembl
ENSRNOG00060017986
resolver
ensembl
ENSRNOG00065016811
resolver
ensp
ENSRNOP00000003716
resolver
ensp
ENSRNOP00055008065
resolver
ensp
ENSRNOP00060025042
resolver
ensp
ENSRNOP00065022176
resolver
enst
ENSRNOT00000003716
resolver
enst
ENSRNOT00055010389
resolver
enst
ENSRNOT00060030933
resolver
enst
ENSRNOT00065028060
resolver
genesymbol
Ereg
resolver
uniprot_entry
EREG_RAT
resolver
amino_acid_sequence
METFPAAWVLALLCLGSHLLQAVISTTVIPSCIPEESEDNCTALVQMEDDPRVAQVLITKCSSDMDGYCLHGHCIYLVDMSEKYCRCEVGYTGLRCEHFFLTVHQPLSREYVALTVILVFLFLIVTAGSMYYFCRWYRNRKSKKSREEYERVTSGGPGLPQV
uniprot
proteins
function
FUNCTION: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9990076). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). {ECO:0000269|PubMed:9990076, ECO:0000303|PubMed:24631357}.
uniprot
proteins
mass_dalton
18404
uniprot
proteins
pubmed
12446600
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
24631357
uniprot
proteins
pubmed
9990076
uniprot
proteins
sequence_length
162
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Epiregulin]: Secreted, extracellular space {ECO:0000250|UniProtKB:O14944}.; SUBCELLULAR LOCATION: [Proepiregulin]: Cell membrane {ECO:0000250|UniProtKB:O14944}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:O14944}.
uniprot
proteins
transmembrane_region
TRANSMEM 113..133; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins