Pacs2
entrez
217893
canonical
uniprot
Q3V3Q7
canonical
ensembl
ENSMUSG00000021143
resolver
ensp
ENSMUSP00000081953
resolver
ensp
ENSMUSP00000152145
resolver
ensp
ENSMUSP00000152439
resolver
ensp
ENSMUSP00000297156
resolver
ensp
ENSMUSP00000297157
resolver
ensp
ENSMUSP00000297160
resolver
ensp
ENSMUSP00000297163
resolver
ensp
ENSMUSP00000297166
resolver
ensp
ENSMUSP00000297168
resolver
ensp
ENSMUSP00000297181
resolver
ensp
ENSMUSP00000326892
resolver
enst
ENSMUST00000084891
resolver
enst
ENSMUST00000220541
resolver
enst
ENSMUST00000223502
resolver
genesymbol
Pacs2
resolver
genesymbol_syn
Kiaa0602
resolver
genesymbol_syn
Pacs1l
resolver
uniprot
A0A1Y7VLZ7
resolver
uniprot
E9Q7E9
resolver
uniprot
E9QKL3
resolver
uniprot
Q80TW2
resolver
uniprot
Q80VG3
resolver
uniprot_entry
A0A1Y7VLZ7_MOUSE
resolver
uniprot_entry
E9Q7E9_MOUSE
resolver
uniprot_entry
PACS2_MOUSE
resolver
uniprot_sec
E9QKL3
resolver
uniprot_sec
Q80TW2
resolver
uniprot_sec
Q80VG3
resolver
amino_acid_sequence
MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLAVLRELEKELLSVVIAVKMQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAAGSINMAEVMQHPSEGGQVLSLCSSIKEASVKVAEIWIVSLSSQPIDHEDSAMQAGPKTKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQKVVALLRRFKVSEEVLDSEQDPAEHVPEVEEDLDLLYDTLDVENPSDSGPDMDDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHREPPSPADVPEKTRSLGGKQQLSDSVSDTVALSAAVPREPSGQPEDSPEAETSTLDVFTEKLPPSGRIIKTESLVIPSTRSESKPAGRRGRSTSLKERQPARPQNERANSLDNERCPDTRSQLQIPRKTVYDQLNHILISDDQLPENIILVNTSDWQGQFLSDVLQKHTLPVVCTCSAADVQAAFSTIVSRIQRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLIIPLGSHPVARYLGSVDYRYNNFFQDLAWRDLFNKLEAQSSVQDTPDIVSRITQYISGANCAHQLPIAEAMLTYKQKSPDEESSQRFIPFVGVVKVGIVEPSSATSGDSDDAAPSSSSILSSTPPSASTSPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDMPTTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKTKDKEVESKSQCIEGISRLICTAKHQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF
uniprot
proteins
function
FUNCTION: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments (By similarity). {ECO:0000250|UniProtKB:Q86VP3}.
uniprot
proteins
mass_dalton
94932
uniprot
proteins
protein_family
PACS family
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
862
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q86VP3}. Mitochondrion {ECO:0000250|UniProtKB:Q86VP3}.
uniprot
proteins