Acsl1
entrez
14081
canonical
uniprot
P41216
canonical
ensembl
ENSMUSG00000018796
resolver
ensp
ENSMUSP00000034046
resolver
ensp
ENSMUSP00000106000
resolver
ensp
ENSMUSP00000106001
resolver
ensp
ENSMUSP00000297679
resolver
ensp
ENSMUSP00000297695
resolver
ensp
ENSMUSP00000297697
resolver
ensp
ENSMUSP00000297698
resolver
ensp
ENSMUSP00000297702
resolver
ensp
ENSMUSP00000297707
resolver
enst
ENSMUST00000034046
resolver
enst
ENSMUST00000110371
resolver
enst
ENSMUST00000110372
resolver
genesymbol
Acsl1
resolver
genesymbol_syn
Acsl2
resolver
genesymbol_syn
Facl2
resolver
uniprot
D3Z041
resolver
uniprot
Q6GTG6
resolver
uniprot
Q9DBK5
resolver
uniprot_entry
ACSL1_MOUSE
resolver
uniprot_entry
D3Z041_MOUSE
resolver
uniprot_sec
Q6GTG6
resolver
uniprot_sec
Q9DBK5
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited at high temperature and by arachidonate. {ECO:0000250|UniProtKB:P18163}.
uniprot
proteins
amino_acid_sequence
MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEIAGTTDGIRRSAVLEDDKLLVYYYDDVRTMYDGFQRGIQVSNNGPCLGSRKPNQPYEWISYKEVAELAECIGSGLIQKGFKPCSEQFIGLFSQNRPEWVIVEQGCFSYSMVVVPLYDTLGADAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYGSDLVERGKKCGVEIISLKALEDLGRVNRVKPKPPEPEDLAIICFTSGTTGNPKGAMITHQNIINDCSGFIKATESAFIASTDDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSLKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRTALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYVKLVDVEEMNYLASKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAVVVPDVESLPSWAQKRGLQGSFEELCRNKDINKAILDDLLKLGKEAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYATIKI
uniprot
proteins
ec_number
6.2.1.15
uniprot
proteins
ec_number
6.2.1.24
uniprot
proteins
ec_number
6.2.1.3
uniprot
proteins
function
FUNCTION: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity). Preferentially uses palmitoleate, oleate and linoleate (By similarity). Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs). {ECO:0000250|UniProtKB:P18163, ECO:0000250|UniProtKB:P33121}.
uniprot
proteins
mass_dalton
77951
uniprot
proteins
protein_family
ATP-dependent AMP-binding enzyme family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
sequence_length
699
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P33121}; Single-pass type III membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins