Magt1
entrez
67075
canonical
uniprot
Q9CQY5
canonical
ensembl
ENSMUSG00000031232
resolver
ensp
ENSMUSP00000033583
resolver
ensp
ENSMUSP00000109196
resolver
ensp
ENSMUSP00000120994
resolver
ensp
ENSMUSP00000158823
resolver
ensp
ENSMUSP00000163098
resolver
enst
ENSMUST00000033583
resolver
enst
ENSMUST00000238718
resolver
genesymbol
Magt1
resolver
genesymbol_syn
Iag2
resolver
uniprot
A2ADH1
resolver
uniprot
Q3UW45
resolver
uniprot
Q9CWX5
resolver
uniprot
Q9CZT3
resolver
uniprot_entry
A2ADH1_MOUSE
resolver
uniprot_entry
MAGT1_MOUSE
resolver
uniprot_sec
Q3UW45
resolver
uniprot_sec
Q9CWX5
resolver
uniprot_sec
Q9CZT3
resolver
amino_acid_sequence
MASPRWFWSVCAIAAVALLLVSKVPSASAQRKKEMVLSEKVSQLMEWANKRPVIRMNGDKFRRLVKAPPRNYSVVVMFTALQLHRQCVVCKQADEEFQILANSWRYSNAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPPKGKPKRADTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRRMMCIAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS
uniprot
proteins
function
FUNCTION: Accessory component of the STT3B-containing form of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Also has oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition. Could indirectly play a role in Mg(2+) transport in epithelial cells (Probable). {ECO:0000250|UniProtKB:Q9H0U3, ECO:0000305|PubMed:15804357}.
uniprot
proteins
mass_dalton
37970
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q9H0U3}.
uniprot
proteins
protein_family
OST3/OST6 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15804357
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9H0U3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9H0U3}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9H0U3}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 185..205; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 210..230; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 271..291; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 301..321; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins