Pitx1
entrez
18740
canonical
uniprot
P70314
canonical
ensembl
ENSMUSG00000021506
resolver
ensp
ENSMUSP00000021968
resolver
enst
ENSMUST00000021968
resolver
genesymbol
Pitx1
resolver
genesymbol_syn
Bft
resolver
genesymbol_syn
Potx
resolver
genesymbol_syn
Ptx1
resolver
uniprot
O54742
resolver
uniprot
P70427
resolver
uniprot
Q3UQH0
resolver
uniprot_entry
PITX1_MOUSE
resolver
uniprot_entry
Q3UQH0_MOUSE
resolver
uniprot_sec
O54742
resolver
uniprot_sec
P70427
resolver
amino_acid_sequence
MDAFKGGMSLERLPEGLRPPPPPPHDMGPSFHLARAADPREPLENSASESSDADLPDKERGGEAKGPEDGGAGSAGCGGGAEDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
uniprot
proteins
function
FUNCTION: Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. Can independently activate and synergize with PIT-1 on pituitary-specific target gene promoters, thus may subserve functions in generating both precursor and specific cell phenotypes in the anterior pituitary gland and in several other organs. Can activate pituitary transcription of the proopiomelanocortin gene. {ECO:0000250|UniProtKB:P56673, ECO:0000269|PubMed:8675014, ECO:0000269|PubMed:8755540}.
uniprot
proteins
mass_dalton
34075
uniprot
proteins
protein_family
Bicoid subfamily
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8675014
uniprot
proteins
pubmed
8755540
uniprot
proteins
pubmed
9070926
uniprot
proteins
pubmed
9226452
uniprot
proteins
sequence_length
315
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins