HIGD2A
entrez
192286
canonical
uniprot
Q9BW72
canonical
ensembl
ENSG00000146066
resolver
ensp
ENSP00000274787
resolver
enst
ENST00000274787
resolver
genesymbol
HIGD2A
resolver
hgnc
HGNC:28311
resolver
uniprot_entry
HIG2A_HUMAN
resolver
amino_acid_sequence
MATPGPVIPEVPFEPSKPPVIEGLSPTVYRNPESFKEKFVRKTRENPVVPIGCLATAAALTYGLYSFHRGNSQRSQLMMRTRIAAQGFTVAAILLGLAVTAMKSRP
uniprot
proteins
function
FUNCTION: Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May be involved in cytochrome c oxidase activity. May play a role in the assembly of respiratory supercomplexes. {ECO:0000269|PubMed:22342701}.
uniprot
proteins
mass_dalton
11529
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22342701
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
106
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255|PROSITE-ProRule:PRU00836, ECO:0000269|PubMed:22342701}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00836, ECO:0000269|PubMed:22342701}. Mitochondrion inner membrane {ECO:0000305|PubMed:22342701}.
uniprot
proteins
transmembrane_region
TRANSMEM 47..67; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00836"; TRANSMEM 83..103; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00836
uniprot
proteins