OR4C12
entrez
283093
canonical
uniprot
Q96R67
canonical
ensembl
ENSG00000221954
resolver
ensembl
ENSG00000284255
resolver
ensp
ENSP00000334418
resolver
ensp
ENSP00000491819
resolver
enst
ENST00000335238
resolver
enst
ENST00000639310
resolver
genesymbol
OR4C12
resolver
hgnc
HGNC:15168
resolver
uniprot
B2RNF0
resolver
uniprot
Q6IF49
resolver
uniprot_entry
OR4CC_HUMAN
resolver
uniprot_sec
B2RNF0
resolver
uniprot_sec
Q6IF49
resolver
amino_acid_sequence
MEKKKNVTEFILIGLTQNPIMEKVTFVVFLVLYMITLSGNLLIVVTITTSQALSSPMYFFLTHLSLIDTVYSSSSAPKLIVDSFQEKKIISFNGCMAQAYAEHIFGATEIILLTVMACDCYVAICKPLNYTTIMSHSLCILLVAVAWVGGFLHATIQILFTVWLPFCGPNVIGHFMCDLYPLLKLVCIDTHTLGLFVAVNSGFICLLNFLILVVSYVIILRSLKNNSLEGRCKALSTCISHIIVVVLFFVPCIFVYLRSVTTLPIDKAVAVFYTMVVPMLNPVVYTLRNAEVKSAIRKLWRKKVTSDND
uniprot
proteins
function
FUNCTION: Acts as a receptor for R-(-)-carvone in pancreatic cells, initiating signaling pathways involving GNAS, elevated intracellular Ca(2+), and increased cAMP levels. Upon activation, promotes glucose-stimulated insulin secretion. {ECO:0000250|UniProtKB:Q8VEZ1}.
uniprot
proteins
mass_dalton
34491
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12213199
uniprot
proteins
pubmed
14983052
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
309
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 24..47; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 56..77; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 99..118; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 138..156; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 194..217; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 234..256; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 268..287; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins