Lsm6
entrez
78651
canonical
uniprot
P62313
canonical
ensembl
ENSMUSG00000031683
resolver
ensp
ENSMUSP00000049722
resolver
ensp
ENSMUSP00000119841
resolver
ensp
ENSMUSP00000148221
resolver
ensp
ENSMUSP00000201249
resolver
ensp
ENSMUSP00000201251
resolver
enst
ENSMUST00000051867
resolver
enst
ENSMUST00000130325
resolver
enst
ENSMUST00000146824
resolver
genesymbol
Lsm6
resolver
uniprot
Q542U7
resolver
uniprot
Q9Y4Y8
resolver
uniprot_entry
LSM6_MOUSE
resolver
uniprot_entry
Q542U7_MOUSE
resolver
uniprot_sec
Q9Y4Y8
resolver
amino_acid_sequence
MSLRKQTPSDFLKQIIGRPVVVKLNSGVDYRGVLACLDGYMNIALEQTEEYVNGQLKNKYGDAFIRGNNVLYISTQKRRM
uniprot
proteins
function
FUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. {ECO:0000250|UniProtKB:P62312}.
uniprot
proteins
mass_dalton
9128
uniprot
proteins
protein_family
SmF/LSm6 subfamily
uniprot
proteins
protein_family
SnRNP Sm proteins family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
80
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P62312}. Nucleus {ECO:0000250|UniProtKB:P62312}.
uniprot
proteins