SP8
entrez
221833
canonical
uniprot
Q8IXZ3
canonical
ensembl
ENSG00000164651
resolver
ensp
ENSP00000354482
resolver
ensp
ENSP00000408792
resolver
genesymbol
SP8
resolver
hgnc
HGNC:19196
resolver
uniprot
A8K350
resolver
uniprot
Q7Z615
resolver
uniprot
Q7Z616
resolver
uniprot
Q96MJ1
resolver
uniprot_entry
A8K350_HUMAN
resolver
uniprot_entry
SP8_HUMAN
resolver
uniprot_sec
Q7Z615
resolver
uniprot_sec
Q7Z616
resolver
uniprot_sec
Q96MJ1
resolver
amino_acid_sequence
MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
uniprot
proteins
function
FUNCTION: Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
48674
uniprot
proteins
protein_family
Sp1 C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15533246
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
31375868
uniprot
proteins
sequence_length
490
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins