Raly
entrez
19383
canonical
uniprot
Q64012
canonical
ensembl
ENSMUSG00000027593
resolver
ensp
ENSMUSP00000029120
resolver
ensp
ENSMUSP00000058105
resolver
ensp
ENSMUSP00000105323
resolver
ensp
ENSMUSP00000112090
resolver
ensp
ENSMUSP00000166130
resolver
ensp
ENSMUSP00000166133
resolver
ensp
ENSMUSP00000166134
resolver
ensp
ENSMUSP00000326494
resolver
ensp
ENSMUSP00000326495
resolver
ensp
ENSMUSP00000326504
resolver
ensp
ENSMUSP00000357637
resolver
genesymbol
Raly
resolver
genesymbol_syn
Merc
resolver
uniprot
A2AU63
resolver
uniprot
Q3U3F6
resolver
uniprot
Q99K76
resolver
uniprot
Q9CXH8
resolver
uniprot
Q9QZX6
resolver
uniprot_entry
Q3U3F6_MOUSE
resolver
uniprot_entry
RALY_MOUSE
resolver
uniprot_sec
A2AU63
resolver
uniprot_sec
Q99K76
resolver
uniprot_sec
Q9CXH8
resolver
uniprot_sec
Q9QZX6
resolver
amino_acid_sequence
MSLKIQTSNVTNKNDPKSINSRVFIGNLNTAVVKKSDVETIFSKYGRVAGCSVHKGYAFVQYANERHARAAVLGENGRVLAGQTLDINMAGEPKPNRPKGLKRAATAIYSGYSFDYDYYQDYFCARLFDYRGRLSPVPVPRAVPVKRPRVTVPLVRRVKTTIPVKLFARSTAVTTGSAKIKLKSSELQTIKTELTQIKSNIDALLGRLEQIAEEQKANPDGKKKGDSSSGGGGGSSGGGGSSNVGGGSSGGSGSCSSSSRLPAPQEDTASEAGTPQGEVQTRDDGDEEGLLTHSEEELEHSQDTDAEDGALQ
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Raly are the cause of lethal yellow mutation (A(y)), a dominant allele that cause embryonic lethality when homozygous, and pleiotropic effects when heterozygous, including yellow pelage, obesity, non-insulin dependent diabetes and increased tumor susceptibility. A(y) is due to a 170 kb deletion that removes all but the promoter and non-coding first exon of Raly and links them to the ASIP/Agouti gene. {ECO:0000269|PubMed:8050375, ECO:0000269|PubMed:8319910}.
uniprot
proteins
function
FUNCTION: RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver (PubMed:27251289). Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (PubMed:27251289). May be a heterogeneous nuclear ribonucleoprotein (hnRNP) (By similarity). {ECO:0000250|UniProtKB:Q9UKM9, ECO:0000269|PubMed:27251289}.
uniprot
proteins
mass_dalton
33188
uniprot
proteins
protein_family
RALY subfamily
uniprot
proteins
protein_family
RRM HNRPC family
uniprot
proteins
pubmed
10500250
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
27251289
uniprot
proteins
pubmed
8050375
uniprot
proteins
pubmed
8319910
uniprot
proteins
sequence_length
312
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:27251289}.
uniprot
proteins