H1-7
entrez
341567
canonical
uniprot
Q75WM6
canonical
ensembl
ENSG00000187166
resolver
ensp
ENSP00000334805
resolver
enst
ENST00000335017
resolver
genesymbol
H1-7
resolver
genesymbol_syn
H1FNT
resolver
genesymbol_syn
HANP1
resolver
hgnc
HGNC:24893
resolver
uniprot
A0A140VK96
resolver
uniprot
Q147U8
resolver
uniprot
Q5GKZ5
resolver
uniprot
Q7Z694
resolver
uniprot_entry
A0A140VK96_HUMAN
resolver
uniprot_entry
H1FNT_HUMAN
resolver
uniprot_sec
Q147U8
resolver
uniprot_sec
Q5GKZ5
resolver
uniprot_sec
Q7Z694
resolver
amino_acid_sequence
MEQALTGEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQRTIQ
uniprot
proteins
function
FUNCTION: Essential for normal spermatogenesis and male fertility (PubMed:16533358). Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. {ECO:0000250|UniProtKB:Q8CJI4, ECO:0000269|PubMed:16533358}.
uniprot
proteins
mass_dalton
28116
uniprot
proteins
protein_family
Histone H1/H5 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15710904
uniprot
proteins
pubmed
16533358
uniprot
proteins
pubmed
16541075
uniprot
proteins
sequence_length
255
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8CJI4}. Chromosome {ECO:0000250|UniProtKB:Q8CJI4}. Note=In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole. {ECO:0000250|UniProtKB:Q8CJI4}.
uniprot
proteins