Rpn2
entrez
64701
canonical
uniprot
P25235
canonical
ensembl
ENSRNOG00000007492
resolver
ensembl
ENSRNOG00055026457
resolver
ensembl
ENSRNOG00060022221
resolver
ensembl
ENSRNOG00065026897
resolver
ensp
ENSRNOP00000063207
resolver
ensp
ENSRNOP00000076455
resolver
ensp
ENSRNOP00055037879
resolver
ensp
ENSRNOP00060033044
resolver
ensp
ENSRNOP00065038456
resolver
enst
ENSRNOT00000068135
resolver
enst
ENSRNOT00000118622
resolver
enst
ENSRNOT00055046151
resolver
enst
ENSRNOT00060040021
resolver
enst
ENSRNOT00065046879
resolver
genesymbol
Rpn2
resolver
uniprot
A0A8L2QVV5
resolver
uniprot
Q6P9X0
resolver
uniprot_entry
A0A8L2QVV5_RAT
resolver
uniprot_entry
RPN2_RAT
resolver
uniprot_sec
Q6P9X0
resolver
amino_acid_sequence
MAPPGSSAVFLLALTITASTQALTPTHYLTKHDVERLKASLDRPFTSLESAFYSIVGLNSLGAQVPDVKKACAFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETRDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASHEALGALTARLSKEETVLATVQALHTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLELTALFVAATYKLMDHVGTEPSIKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHVPVVVVPEGSASDTQEQAILRLQVSSVLSQPLAQAAVKLEHAKSVASRATVLQKMPFSLVGDVFELNFKNVKLPSGYYDFSVRVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTVIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQQAVKRTAH
uniprot
proteins
function
FUNCTION: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. {ECO:0000250|UniProtKB:F1PCT7}.
uniprot
proteins
mass_dalton
69078
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:P04844}.
uniprot
proteins
protein_family
SWP1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1710116
uniprot
proteins
sequence_length
631
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:F1PCT7}. Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 541..561; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 572..592; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 597..617; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins