Etfb
entrez
110826
canonical
uniprot
Q9DCW4
canonical
ensembl
ENSMUSG00000004610
resolver
ensp
ENSMUSP00000004729
resolver
enst
ENSMUST00000004729
resolver
genesymbol
Etfb
resolver
uniprot
Q810V3
resolver
uniprot_entry
ETFB_MOUSE
resolver
uniprot_sec
Q810V3
resolver
amino_acid_sequence
MAELRALVAVKRVIDFAVKIRVKPDKSGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEIIAVSCGPSQCQETIRTALAMGADRGIHVEIPGAQAESLGPLQVARVLAKLAEKEKVDLLFLGKQAIDDDCNQTGQMTAGLLDWPQGTFASQVTLEGDKVKVEREIDGGLETLRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVVKAGDLGVDLTSKVSVISVEEPPQRSAGVKVETTEDLVAKLKEVGRI
uniprot
proteins
function
FUNCTION: Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (By similarity). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism (PubMed:25023281). ETFB binds an AMP molecule that probably has a purely structural role (By similarity). {ECO:0000250|UniProtKB:P38117, ECO:0000269|PubMed:25023281}.
uniprot
proteins
mass_dalton
27623
uniprot
proteins
post_translational_modification
PTM: Methylated (PubMed:25023281). Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from acyl-CoA dehydrogenases. {ECO:0000250|UniProtKB:P38117, ECO:0000269|PubMed:25023281}.
uniprot
proteins
protein_family
ETF beta-subunit/FixA family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
25023281
uniprot
proteins
sequence_length
255
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:P38117}.
uniprot
proteins