Mgmt
entrez
17314
canonical
uniprot
P26187
canonical
ensembl
ENSMUSG00000054612
resolver
ensp
ENSMUSP00000080224
resolver
ensp
ENSMUSP00000240313
resolver
ensp
ENSMUSP00000351100
resolver
enst
ENSMUST00000081510
resolver
genesymbol
Mgmt
resolver
uniprot
Q4VA39
resolver
uniprot
Q54A49
resolver
uniprot_entry
MGMT_MOUSE
resolver
uniprot_entry
Q4VA39_MOUSE
resolver
uniprot_sec
Q54A49
resolver
amino_acid_sequence
MAETCKMKYSVLDSPLGKMELSGCERGLHGIRLLSGKTPNTDPTEAPATPEVLGGPEGVPEPLVQCTAWLEAYFREPAATEGLPLPALHHPVFQQDSFTRQVLWKLLKVVKFGETVSYQQLAALAGNPKAARAVGGAMRSNPVPILIPCHRVVRSDGAIGHYSGGGQAVKEWLLAHEGIPTGQPASKGLGLTGTWLKSSFESTSSEPSGRN
uniprot
proteins
ec_number
2.1.1.63
uniprot
proteins
function
FUNCTION: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
uniprot
proteins
mass_dalton
22435
uniprot
proteins
protein_family
MGMT family
uniprot
proteins
pubmed
1371399
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
211
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins