BMP15
entrez
9210
canonical
uniprot
O95972
canonical
ensembl
ENSG00000130385
resolver
ensp
ENSP00000252677
resolver
enst
ENST00000252677
resolver
genesymbol
BMP15
resolver
genesymbol_syn
GDF9B
resolver
hgnc
HGNC:1068
resolver
uniprot
Q17RM6
resolver
uniprot
Q5JST1
resolver
uniprot
Q9UMS1
resolver
uniprot_entry
BMP15_HUMAN
resolver
uniprot_sec
Q17RM6
resolver
uniprot_sec
Q5JST1
resolver
uniprot_sec
Q9UMS1
resolver
amino_acid_sequence
MVLLSILRILFLCELVLFMEHRAQMAEGGQSSIALLAEAPTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQLTRFNLSCHVEPWVQKNPTNHFPSSEGDSSKPSLMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWHGTSSLDIAFLLLYFNDTHKSIRKAKFLPRGMEEFMERESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
uniprot
proteins
disease_involvement
DISEASE: Ovarian dysgenesis 2 (ODG2) [MIM:300510]: A disorder characterized by lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism as a result of streak gonads. {ECO:0000269|PubMed:15136966}. Note=The disease is caused by variants affecting the gene represented in this entry.; DISEASE: Premature ovarian failure 4 (POF4) [MIM:300510]: An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. {ECO:0000269|PubMed:16464940, ECO:0000269|PubMed:16508750, ECO:0000269|PubMed:16645022, ECO:0000269|PubMed:19263482, ECO:0000269|PubMed:19438907}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. {ECO:0000269|PubMed:18227435}.
uniprot
proteins
mass_dalton
45055
uniprot
proteins
protein_family
TGF-beta family
uniprot
proteins
pubmed
10443672
uniprot
proteins
pubmed
15136966
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
16464940
uniprot
proteins
pubmed
16508750
uniprot
proteins
pubmed
16645022
uniprot
proteins
pubmed
18227435
uniprot
proteins
pubmed
19263482
uniprot
proteins
pubmed
19438907
uniprot
proteins
pubmed
21970812
uniprot
proteins
pubmed
28585349
uniprot
proteins
pubmed
9849956
uniprot
proteins
sequence_length
392
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins