Ptbp2
entrez
56195
canonical
uniprot
Q91Z31
canonical
ensembl
ENSMUSG00000028134
resolver
ensp
ENSMUSP00000029780
resolver
ensp
ENSMUSP00000143510
resolver
genesymbol
Ptbp2
resolver
genesymbol_syn
Brptb
resolver
genesymbol_syn
Nptb
resolver
uniprot
Q7TNW7
resolver
uniprot
Q9CUW2
resolver
uniprot
Q9QYC2
resolver
uniprot
Q9R0V9
resolver
uniprot_entry
PTBP2_MOUSE
resolver
uniprot_sec
Q7TNW7
resolver
uniprot_sec
Q9CUW2
resolver
uniprot_sec
Q9QYC2
resolver
uniprot_sec
Q9R0V9
resolver
amino_acid_sequence
MDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSGMVVTANGNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQVVLQAVTAVQTANTPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI
uniprot
proteins
function
FUNCTION: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing (PubMed:10829067, PubMed:30638744). May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection (PubMed:10829067). In addition to its function in pre-mRNA splicing, also plays a role in the regulation of translation (PubMed:11726525). {ECO:0000269|PubMed:10829067, ECO:0000269|PubMed:11726525, ECO:0000269|PubMed:30638744}.
uniprot
proteins
mass_dalton
57489
uniprot
proteins
pubmed
10829067
uniprot
proteins
pubmed
11231079
uniprot
proteins
pubmed
11726525
uniprot
proteins
pubmed
12213192
uniprot
proteins
pubmed
14667811
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30638744
uniprot
proteins
sequence_length
531
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10829067}.
uniprot
proteins