Tmem178a
entrez
362691
canonical
uniprot
Q68FV0
canonical
ensembl
ENSRNOG00000007907
resolver
ensembl
ENSRNOG00055021468
resolver
ensembl
ENSRNOG00060014558
resolver
ensembl
ENSRNOG00065014537
resolver
ensp
ENSRNOP00000010927
resolver
ensp
ENSRNOP00055029789
resolver
ensp
ENSRNOP00060019817
resolver
ensp
ENSRNOP00065018717
resolver
enst
ENSRNOT00000010927
resolver
enst
ENSRNOT00055036679
resolver
enst
ENSRNOT00060024881
resolver
enst
ENSRNOT00065024014
resolver
genesymbol
Tmem178a
resolver
genesymbol_syn
Tmem178
resolver
uniprot_entry
T178A_RAT
resolver
amino_acid_sequence
MEPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDPRRHKESCERSRAGADPPDQKNRLMPLSHLPLRDSPPLGRRLLPGGPGRSDPESWRSLLGLGGLDAECGRPLFATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAVKYHFSQPIRLRNIPFNLTKIIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASVSYDLNRVPKLIYSLPHDVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAHLKSGRDSTV
uniprot
proteins
function
FUNCTION: Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. {ECO:0000250|UniProtKB:Q9CZ16}.
uniprot
proteins
mass_dalton
33080
uniprot
proteins
protein_family
TMEM178 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9CZ16}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 180..200; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins