IMMT
entrez
10989
canonical
uniprot
Q16891
canonical
ensembl
ENSG00000132305
resolver
ensp
ENSP00000254636
resolver
ensp
ENSP00000387262
resolver
ensp
ENSP00000396899
resolver
ensp
ENSP00000407788
resolver
ensp
ENSP00000415762
resolver
ensp
ENSP00000580443
resolver
ensp
ENSP00000580446
resolver
ensp
ENSP00000580447
resolver
ensp
ENSP00000593580
resolver
ensp
ENSP00000632865
resolver
ensp
ENSP00000632866
resolver
ensp
ENSP00000632867
resolver
ensp
ENSP00000632869
resolver
ensp
ENSP00000632871
resolver
ensp
ENSP00000632872
resolver
ensp
ENSP00000632873
resolver
ensp
ENSP00000632875
resolver
ensp
ENSP00000632876
resolver
ensp
ENSP00000632881
resolver
ensp
ENSP00000632882
resolver
ensp
ENSP00000632884
resolver
ensp
ENSP00000632887
resolver
ensp
ENSP00000690524
resolver
ensp
ENSP00000690540
resolver
ensp
ENSP00000775561
resolver
ensp
ENSP00000785299
resolver
ensp
ENSP00000785300
resolver
ensp
ENSP00000785301
resolver
ensp
ENSP00000785302
resolver
enst
ENST00000254636
resolver
genesymbol
IMMT
resolver
genesymbol_syn
HMP
resolver
genesymbol_syn
MIC60
resolver
genesymbol_syn
MINOS2
resolver
hgnc
HGNC:6047
resolver
uniprot
B1H0U5
resolver
uniprot
B2R5N6
resolver
uniprot
B4DS66
resolver
uniprot
C9J406
resolver
uniprot
Q14539
resolver
uniprot
Q15092
resolver
uniprot
Q68D41
resolver
uniprot
Q69HW5
resolver
uniprot
Q6IBL0
resolver
uniprot
Q7Z3X1
resolver
uniprot
Q8TAJ5
resolver
uniprot
Q9P0V2
resolver
uniprot_entry
B4DS66_HUMAN
resolver
uniprot_entry
C9J406_HUMAN
resolver
uniprot_entry
MIC60_HUMAN
resolver
uniprot_sec
B1H0U5
resolver
uniprot_sec
B2R5N6
resolver
uniprot_sec
Q14539
resolver
uniprot_sec
Q15092
resolver
uniprot_sec
Q68D41
resolver
uniprot_sec
Q69HW5
resolver
uniprot_sec
Q6IBL0
resolver
uniprot_sec
Q7Z3X1
resolver
uniprot_sec
Q8TAJ5
resolver
uniprot_sec
Q9P0V2
resolver
amino_acid_sequence
MLRACQLSGVTAAAQSCLCGKFVLRPLRPCRRYSTSGSSGLTTGKIAGAGLLFVGGGIGGTILYAKWDSHFRESVEKTIPYSDKLFEMVLGPAAYNVPLPKKSIQSGPLKISSVSEVMKESKQPASQLQKQKGDTPASATAPTEAAQIISAAGDTLSVPAPAVQPEESLKTDHPEIGEGKPTPALSEEASSSSIRERPPEEVAARLAQQEKQEQVKIESLAKSLEDALRQTASVTLQAIAAQNAAVQAVNAHSNILKAAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKSVIENAKKKEVAGAKPHITAAEGKLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIKANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQLKPPPELCPEDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGTTQVQPE
uniprot
proteins
function
FUNCTION: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824). Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824). {ECO:0000269|PubMed:22114354, ECO:0000269|PubMed:25781180, ECO:0000269|PubMed:32567732, ECO:0000269|PubMed:33130824}.
uniprot
proteins
mass_dalton
83678
uniprot
proteins
protein_family
MICOS complex subunit Mic60 family
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21081504
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22114354
uniprot
proteins
pubmed
22228767
uniprot
proteins
pubmed
22252321
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24687277
uniprot
proteins
pubmed
25764979
uniprot
proteins
pubmed
25781180
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
25997101
uniprot
proteins
pubmed
31644573
uniprot
proteins
pubmed
32567732
uniprot
proteins
pubmed
33130824
uniprot
proteins
pubmed
34344827
uniprot
proteins
pubmed
36127429
uniprot
proteins
pubmed
36658336
uniprot
proteins
pubmed
8039717
uniprot
proteins
pubmed
9168817
uniprot
proteins
sequence_length
758
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:25764979, ECO:0000269|PubMed:25997101}; Single-pass membrane protein {ECO:0000255}. Mitochondrion {ECO:0000269|PubMed:25781180}.
uniprot
proteins
transmembrane_region
TRANSMEM 46..64; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins