Slc25a48
entrez
328258
canonical
uniprot
Q8BW66
canonical
ensembl
ENSMUSG00000021509
resolver
ensp
ENSMUSP00000021971
resolver
ensp
ENSMUSP00000326679
resolver
enst
ENSMUST00000021971
resolver
genesymbol
Slc25a48
resolver
uniprot
Q3KNJ4
resolver
uniprot_entry
S2548_MOUSE
resolver
uniprot_sec
Q3KNJ4
resolver
amino_acid_sequence
MGSFQLEDFVAGWIGGVASVIVGYPLDTVKTRLQAGVGYANTFNCIRMVYKRERVFGFFKGMSFPLASIAIYNSVVFGVFSNTQRFLSKYRCGELEAGPGRSLSDLLLASMLTGVVSVGLGGPVELIKIRLQMQTQPFREASHGLKSRAVAAYQGPVHCIATIVQMEGLTGLYRGASAMLLRDIPGYCFYFIPYVFLSEWITPEACTGPSPYAAWLAGGIAGAISWGTATPMDVVKSRIQADGVYLNKYRGVVDCISQSYQQEGFKVFFRGITVNAVRGFPMSAAMFLGYELSLKALRGEHTVRSE
uniprot
proteins
function
FUNCTION: Mitochondrial transporter that mediates choline import across the inner mitochondrial membrane, thereby regulating mitochondrial choline levels and downstream metabolism, including betaine and purine nucleotide synthesis. Plays a key role in mitochondrial respiration, brown fat thermogenesis, and the maintenance of mitochondrial membrane integrity. {ECO:0000269|PubMed:39111307}.
uniprot
proteins
mass_dalton
33387
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
39047301
uniprot
proteins
pubmed
39111307
uniprot
proteins
sequence_length
306
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000269|PubMed:39111307}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion inner membrane {ECO:0000269|PubMed:39111307}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..29; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 61..81; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 107..127; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 184..204; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 212..232; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 272..290; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins