Mogat1
entrez
68393
canonical
uniprot
Q91ZV4
canonical
ensembl
ENSMUSG00000012187
resolver
ensp
ENSMUSP00000012331
resolver
ensp
ENSMUSP00000109152
resolver
enst
ENSMUST00000012331
resolver
enst
ENSMUST00000113524
resolver
genesymbol
Mogat1
resolver
genesymbol_syn
Dgat2l1
resolver
uniprot
E9QLA2
resolver
uniprot
Q9DCL0
resolver
uniprot_entry
MOGT1_MOUSE
resolver
uniprot_sec
E9QLA2
resolver
uniprot_sec
Q9DCL0
resolver
amino_acid_sequence
MMVEFAPLNTPLARCLQTAAVLQWVLSFLLLVQVCIGIMVMLVLYNYWFLYIPYLVWFYYDWRTPEQGGRRWNWVQSWPVWKYFKEYFPICLVKTQDLDPGHNYIFGFHPHGIFVPGAFGNFCTKYSDFKKLFPGFTSYLHVAKIWFCFPLFREYLMSNGPVSVSKESLSHVLSKDGGGNVSIIVLGGAKEALEAHPGTFTLCIRQRKGFVKMALTHGASLVPVFSFGENDLYKQINNPKGSWLRTIQDAMYDSMGVALPLIYARGIFQHYFGIMPYRKLIYTVVGRPIPVQQTLNPTSEQIEELHQTYLEELKKLFNEHKGKYGIPEHETLVFK
uniprot
proteins
ec_number
2.3.1.22
uniprot
proteins
function
FUNCTION: Involved in glycerolipid synthesis and lipid metabolism (PubMed:12077311, PubMed:12621063). Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol, mainly at the sn-1 or sn-3 positions (PubMed:12077311, PubMed:12621063). It uses both sn-2-monoacylglycerol (2-acylglycerol) and sn-1-monoacylglycerol (1-acyl-sn-glycerol) equally well as substrates, and uses sn-3-monoacylglycerol (3-acyl-sn-glycerol) with lower efficiency (PubMed:12077311). Probably not involved in absorption of dietary fat in the small intestine. {ECO:0000269|PubMed:12077311, ECO:0000269|PubMed:12621063}.
uniprot
proteins
mass_dalton
38791
uniprot
proteins
pathway_participation
PATHWAY: Glycerolipid metabolism; triacylglycerol biosynthesis. {ECO:0000305|PubMed:12077311, ECO:0000305|PubMed:12621063}.
uniprot
proteins
protein_family
Diacylglycerol acyltransferase family
uniprot
proteins
pubmed
11481335
uniprot
proteins
pubmed
12077311
uniprot
proteins
pubmed
12621063
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16106050
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305|PubMed:12077311}; Multi-pass membrane protein {ECO:0000305|PubMed:12077311}.
uniprot
proteins
transmembrane_region
TRANSMEM 24..44; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins