Minar2
entrez
225583
canonical
uniprot
Q8C4X7
canonical
ensembl
ENSMUSG00000050875
resolver
ensp
ENSMUSP00000113023
resolver
ensp
ENSMUSP00000125952
resolver
ensp
ENSMUSP00000241060
resolver
genesymbol
Minar2
resolver
uniprot
A0A0R4J0Q0
resolver
uniprot
E9Q5J6
resolver
uniprot
Q6DI98
resolver
uniprot_entry
MNARL_MOUSE
resolver
uniprot_sec
A0A0R4J0Q0
resolver
uniprot_sec
E9Q5J6
resolver
uniprot_sec
Q6DI98
resolver
amino_acid_sequence
MKGDMDLSVLPNNNHPDKFLQLDVKSLMRSSTLLQASLARFPGGNYPATQHWQNLVYSQREKTIATQRIKGFGVENPVLPESPPASMSSVMKNNPLYGDITLEEAMEERKKSPSWTIEEYDKHSVHTNLSGHLKENPNDLRFWLGDTYTPGFDTLLKKKKKRNKRSKLCHMGLILLLVASILVTIVTLSTIFS
uniprot
proteins
function
FUNCTION: Binds cholesterol and may regulate the distribution and homeostasis of cholesterol in hair cells (By similarity). May play a role in angiogenesis (By similarity). {ECO:0000250|UniProtKB:F1QEA1, ECO:0000250|UniProtKB:P59773}.
uniprot
proteins
mass_dalton
21854
uniprot
proteins
protein_family
MINAR family
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
32954300
uniprot
proteins
pubmed
35727972
uniprot
proteins
sequence_length
193
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:F1QEA1}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P59773}; Single-pass membrane protein {ECO:0000255}. Note=Localizes to the stereocilia and the apical region of hair cell, apparently around and just below the cuticular plate. Co-localized with cholesterol in the stereocilia. {ECO:0000250|UniProtKB:F1QEA1}.
uniprot
proteins
transmembrane_region
TRANSMEM 172..192; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins