Atp5f1a
entrez
65262
canonical
uniprot
P15999
canonical
ensembl
ENSRNOG00000017032
resolver
ensembl
ENSRNOG00055014298
resolver
ensembl
ENSRNOG00060015154
resolver
ensembl
ENSRNOG00065023837
resolver
ensp
ENSRNOP00000022892
resolver
ensp
ENSRNOP00055020058
resolver
ensp
ENSRNOP00060020821
resolver
ensp
ENSRNOP00065033374
resolver
enst
ENSRNOT00000022892
resolver
enst
ENSRNOT00055024562
resolver
enst
ENSRNOT00060026011
resolver
enst
ENSRNOT00065040892
resolver
genesymbol
Atp5f1a
resolver
genesymbol_syn
Atp5a1
resolver
uniprot
Q6P753
resolver
uniprot_entry
ATPA_RAT
resolver
uniprot_sec
Q6P753
resolver
amino_acid_sequence
MLSVRIAAAVARALPRRAGLVSKNALGSSFVGTRNLHASNTRLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGDELLGRVVDALGNAIDGKGPVGSKIRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDSFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFESAFLSHVVSQHQSLLGNIRSDGKISEQSDAKLKEIVTNFLAGFEP
uniprot
proteins
function
FUNCTION: Subunit alpha, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the catalytic subunit beta (ATP5F1B), forms the catalytic core in the F(1) domain. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity). {ECO:0000250|UniProtKB:P19483, ECO:0000250|UniProtKB:P25705}.
uniprot
proteins
mass_dalton
59754
uniprot
proteins
post_translational_modification
PTM: Acetylated on lysine residues. BLOC1S1 is required for acetylation. {ECO:0000250|UniProtKB:P25705}.
uniprot
proteins
protein_family
ATPase alpha/beta chains family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17575325
uniprot
proteins
pubmed
19423663
uniprot
proteins
pubmed
2137825
uniprot
proteins
pubmed
21926988
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
24098488
uniprot
proteins
pubmed
31511561
uniprot
proteins
pubmed
9736690
uniprot
proteins
sequence_length
553
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:17575325}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:P19483}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19483}; Matrix side {ECO:0000250|UniProtKB:P19483}. Cell membrane {ECO:0000250|UniProtKB:P25705}; Peripheral membrane protein {ECO:0000250|UniProtKB:P25705}; Extracellular side {ECO:0000250|UniProtKB:P25705}. Note=Colocalizes with HRG on the cell surface of T-cells. {ECO:0000250|UniProtKB:P25705}.
uniprot
proteins