Snx32
entrez
225861
canonical
uniprot
Q80ZJ7
canonical
ensembl
ENSMUSG00000056185
resolver
ensp
ENSMUSP00000070915
resolver
ensp
ENSMUSP00000157473
resolver
ensp
ENSMUSP00000316103
resolver
enst
ENSMUST00000070172
resolver
enst
ENSMUST00000237111
resolver
genesymbol
Snx32
resolver
genesymbol_syn
Snx6b
resolver
uniprot
A0A494B972
resolver
uniprot_entry
A0A494B972_MOUSE
resolver
uniprot_entry
SNX32_MOUSE
resolver
amino_acid_sequence
MEEQHQEAGNESKPSSTSVDLQGDSPLQVEISDAVSERDKVKFTVQTKSGLPHFAQSEFSVVRQHEEFIWLHDTYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGNSSITREEFSKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFSVFLEYSQDLSVREKNRKEVLGGLLRSIVRSADEVLITGISGLKEVDDFFEHERTFLVEYHTRIRDTCQRADRVMHSHKCLADNYIPISAALSSLGTQEVNQLKRSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESRQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLLLQNTLVALKGEP
uniprot
proteins
function
FUNCTION: Involved in endosomal trafficking of cargo proteins, including transferrin-bound transferrin receptor (TFRC), cation-independent mannose-6-phosphate receptor (IGF2R) and epidermal growth factor receptor (EGFR). Functions redundantly with other BAR domain-containing sorting nexins in endosome to trans-Golgi network transport of IGF2R. Regulates in coordination with SNX5 sorting and trafficking of EGF-activated EGFR to multivesicular bodies for lysosomal degradation (By similarity). Plays an essential role in neurite outgrowth, controlling basigin/EMMPRIN (BSG) trafficking to the cell surface (PubMed:37158588). {ECO:0000250|UniProtKB:Q86XE0, ECO:0000269|PubMed:37158588}.
uniprot
proteins
mass_dalton
46647
uniprot
proteins
protein_family
Sorting nexin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
37158588
uniprot
proteins
sequence_length
404
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q86XE0}. Early endosome {ECO:0000250|UniProtKB:Q86XE0}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q86XE0}. Recycling endosome {ECO:0000250|UniProtKB:Q86XE0}. Late endosome {ECO:0000250|UniProtKB:Q86XE0}.
uniprot
proteins