KLK3
entrez
354
canonical
uniprot
P07288
canonical
ensembl
ENSG00000142515
resolver
ensp
ENSP00000314151
resolver
ensp
ENSP00000353829
resolver
ensp
ENSP00000471155
resolver
genesymbol
KLK3
resolver
genesymbol_syn
APS
resolver
hgnc
HGNC:6364
resolver
uniprot
C9JXH3
resolver
uniprot
G3V0H4
resolver
uniprot
G3XAE3
resolver
uniprot
Q15096
resolver
uniprot
Q16272
resolver
uniprot
Q546G3
resolver
uniprot
Q86TG8
resolver
uniprot
Q8IXI4
resolver
uniprot_entry
KLK3_HUMAN
resolver
uniprot_entry
Q546G3_HUMAN
resolver
uniprot_sec
C9JXH3
resolver
uniprot_sec
G3V0H4
resolver
uniprot_sec
G3XAE3
resolver
uniprot_sec
Q15096
resolver
uniprot_sec
Q16272
resolver
uniprot_sec
Q86TG8
resolver
uniprot_sec
Q8IXI4
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by SERPINA5. Activity is strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. {ECO:0000269|PubMed:1725227, ECO:0000269|PubMed:18187150}.
uniprot
proteins
amino_acid_sequence
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
uniprot
proteins
ec_number
3.4.21.77
uniprot
proteins
function
FUNCTION: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
uniprot
proteins
mass_dalton
28741
uniprot
proteins
protein_family
Kallikrein subfamily
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
11054574
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1725227
uniprot
proteins
pubmed
18187150
uniprot
proteins
pubmed
23842001
uniprot
proteins
pubmed
2422647
uniprot
proteins
pubmed
2436946
uniprot
proteins
pubmed
2456523
uniprot
proteins
pubmed
2466464
uniprot
proteins
pubmed
2467258
uniprot
proteins
pubmed
2470373
uniprot
proteins
pubmed
2471958
uniprot
proteins
pubmed
2472789
uniprot
proteins
pubmed
3691515
uniprot
proteins
pubmed
7527295
uniprot
proteins
pubmed
7535613
uniprot
proteins
pubmed
8677566
uniprot
proteins
pubmed
9751643
uniprot
proteins
sequence_length
261
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins