Prmt8
entrez
381813
canonical
uniprot
Q6PAK3
canonical
ensembl
ENSMUSG00000030350
resolver
ensp
ENSMUSP00000032500
resolver
enst
ENSMUST00000032500
resolver
genesymbol
Prmt8
resolver
genesymbol_syn
Hrmt1l4
resolver
uniprot
Q7M6Z2
resolver
uniprot_entry
ANM8_MOUSE
resolver
uniprot_sec
Q7M6Z2
resolver
amino_acid_sequence
MGMKHSSRCLLLRRKMAENAVESTEVSSAPPQPPQPVIPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR
uniprot
proteins
ec_number
2.1.1.319
uniprot
proteins
function
FUNCTION: S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS. {ECO:0000250|UniProtKB:Q9NR22}.
uniprot
proteins
mass_dalton
45276
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
PRMT8 subfamily
uniprot
proteins
protein_family
Protein arginine N-methyltransferase family
uniprot
proteins
pubmed
12923295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17512914
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
394
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9NR22}; Lipid-anchor {ECO:0000250|UniProtKB:Q9NR22}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9NR22}.
uniprot
proteins