Mafa
entrez
366949
canonical
uniprot
D3ZNT6
canonical
ensembl
ENSRNOG00000007668
resolver
ensp
ENSRNOP00000010084
resolver
enst
ENSRNOT00000010084
resolver
genesymbol
Mafa
resolver
uniprot_entry
MAFA_RAT
resolver
amino_acid_sequence
MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGSSAGGGGSAAQAGGAPGPPSGGPGTVGGASGKAVLEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHSAHHGAHHPAAAAAYEAFRGQSFAGGGGGGADDMGAGHHHGAHHTAHHHHSAHHHHHHHHHHGGSGHHGGGAGHGGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPREPSPAQAGPGAAKGAPDFFL
uniprot
proteins
function
FUNCTION: Transcription factor that activates insulin gene expression (PubMed:15665000). Acts synergistically with NEUROD1/BETA2 and PDX1 (By similarity). Binds the insulin enhancer C1/RIPE3b element (PubMed:15665000). Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence (By similarity). {ECO:0000250|UniProtKB:Q8CF90, ECO:0000250|UniProtKB:Q8NHW3, ECO:0000269|PubMed:15665000}.
uniprot
proteins
mass_dalton
37780
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation by the proteasome. {ECO:0000250|UniProtKB:O57342}.; PTM: Phosphorylated at tyrosines. {ECO:0000250|UniProtKB:Q8CF90}.
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15665000
uniprot
proteins
pubmed
18042454
uniprot
proteins
sequence_length
361
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15665000}.
uniprot
proteins