Q64649
uniprot
Q64649
canonical
activity_regulation
ACTIVITY REGULATION: By phosphorylation of various serine residues and by calcium.
uniprot
proteins
amino_acid_sequence
MRSRSNSGVRLDSYARLVQQHTILCHQNPVTGLLPASYDQKDAWVRDNVYSILAVWGLGLAYRKNADRDEDKAKAYELEQSVVKLMRGLLHCMIRQVDKVESFKYSQSTKDSLHAKYNTKTCATVVGDDQWGHLQLDATSVYLLFLAQMTASGLHIIHSLDEVNFIQNLVFYIEAAYKTADFGIWERGDKTNQGISELNACSVGMAKAALEALDELDLFGVKGGPQSVIHVLADEVQHCQSILNTLLPRASTSKEVDASLLSVISFPAFAVEDSKLVEITKQEIITKLQGRYGCCRFLRDGYKTPKEDPNRLYYEPAELKLFENIECEWPLFWTYFILDGIFSGNTEQVQEYREALDAVLIKGKNGVPLLPELYSVPPDRVDEEYQNPHTVDRVPMGKLPHMWGQSLYILGNLMAEGFLAPGEIDPLNRRFSTVPKPDVVVQVSILAETEEIKAILKDKGIDVETIAEVYPIRVQPARILSHIYSSLGCNSRMKLSGRPYRLMGVLGTSKLYDIRKTIYTFTPQFIDQQQFYLALDNQMIVEMLRTDLSYLCSRWRMTGQPTITFPISHTMLDEDGASLNSSILAALRKMQDGYFGGARIQTGKLSEFLTTSCCTHLSFMDPGPEGKLYSEDYDEDYDDELDSGNWMDSYDSTRNARCGDEVARYLDHLLAHTGPHPKLTPTSRKGGLDRFRAAVQTTCDLMSLVAKAKELHIQNVHMYLPTKLFQPSRPSLNLLDSPESPQDSQVPSVRVEVHLPRDQSGEVDFQSLVSQLKETSSLQEQADILYMLYTMKGPDWNTELYEEGGSTVRELLSELYVKVGEIRHWGLIRYISGILRKKVEALDEACTDLLSYQKHLTVGLPPEPREKTISAPLPYEALTKLIDEASEGDMNISTLTQEIMVYLAMYMRTQPGLFAEMFRLRIGLIIQVMATELAHSLRCSAEEATEGLMNLSPSAMRNLLHHILSGKEFGVERSVRPTDSNVSPAISIHEIGAVGATKTERTGIMQLKSEIKQVEFRRLSVSPESQTSGGHPSSIDLMSPTFLSPAACISASSGSFPTVCEPQTSKDSRQGQWQRRRRLDGALNRVPIGFYQKVWKILQKCHGLSVEGFVLPSSSTREMTPGEIKFSVHVESVLNRVPQPEYRQLLVEAILVLTMLADIEIHSIGSIIAVEKIVHIANDLFLQEKKTLGADDIMLAKDPASGICTLLYDSAPSGRFGTMTYLSKAAATYVQEFLPHSLCAVQ
uniprot
proteins
function
FUNCTION: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
uniprot
proteins
mass_dalton
139155
uniprot
proteins
pathway_participation
PATHWAY: Glycan biosynthesis; glycogen metabolism.
uniprot
proteins
post_translational_modification
PTM: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated. {ECO:0000250|UniProtKB:P18688}.
uniprot
proteins
protein_family
Phosphorylase b kinase regulatory chain family
uniprot
proteins
pubmed
1512265
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1242
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins