Med26
entrez
70625
canonical
uniprot
Q7TN02
canonical
ensembl
ENSMUSG00000045248
resolver
ensp
ENSMUSP00000058697
resolver
enst
ENSMUST00000058534
resolver
genesymbol
Med26
resolver
genesymbol_syn
Crsp7
resolver
uniprot
Q8BUP9
resolver
uniprot
Q8R1G7
resolver
uniprot
Q9CS67
resolver
uniprot_entry
MED26_MOUSE
resolver
uniprot_sec
Q8BUP9
resolver
uniprot_sec
Q8R1G7
resolver
uniprot_sec
Q9CS67
resolver
amino_acid_sequence
MTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPEMGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLEPSDNEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQQLDRADESPGPPYPRGSSRCSFSPRNSRHEGSFSRHRSSYIPKGQVSSPSPWPQPPDNTQVPSPLPLAQPPTPPVRRQELLPNAESPVHWPEQSEGHPRLTGPACRAGFSPDSSKADSDATSSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQEVKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
64680
uniprot
proteins
protein_family
Mediator complex subunit 26 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20111005
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
588
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins