Nrcam
entrez
319504
canonical
uniprot
Q810U4
canonical
ensembl
ENSMUSG00000020598
resolver
ensp
ENSMUSP00000020939
resolver
ensp
ENSMUSP00000106376
resolver
ensp
ENSMUSP00000200848
resolver
ensp
ENSMUSP00000200849
resolver
ensp
ENSMUSP00000200850
resolver
ensp
ENSMUSP00000200851
resolver
ensp
ENSMUSP00000200852
resolver
ensp
ENSMUSP00000200854
resolver
ensp
ENSMUSP00000200857
resolver
ensp
ENSMUSP00000200859
resolver
ensp
ENSMUSP00000200860
resolver
ensp
ENSMUSP00000200861
resolver
ensp
ENSMUSP00000200863
resolver
ensp
ENSMUSP00000200875
resolver
ensp
ENSMUSP00000200878
resolver
ensp
ENSMUSP00000200879
resolver
ensp
ENSMUSP00000200880
resolver
ensp
ENSMUSP00000200883
resolver
ensp
ENSMUSP00000200885
resolver
ensp
ENSMUSP00000200886
resolver
ensp
ENSMUSP00000200900
resolver
ensp
ENSMUSP00000200901
resolver
ensp
ENSMUSP00000200909
resolver
ensp
ENSMUSP00000200914
resolver
ensp
ENSMUSP00000200923
resolver
ensp
ENSMUSP00000200927
resolver
ensp
ENSMUSP00000200929
resolver
ensp
ENSMUSP00000200951
resolver
ensp
ENSMUSP00000200959
resolver
genesymbol
Nrcam
resolver
genesymbol_syn
Kiaa0343
resolver
uniprot
Q6QRP1
resolver
uniprot
Q80U33
resolver
uniprot
Q8BLG8
resolver
uniprot
Q8BX92
resolver
uniprot
Q8BYJ8
resolver
uniprot_entry
NRCAM_MOUSE
resolver
uniprot_entry
Q6QRP1_MOUSE
resolver
uniprot_sec
Q80U33
resolver
uniprot_sec
Q8BLG8
resolver
uniprot_sec
Q8BX92
resolver
uniprot_sec
Q8BYJ8
resolver
amino_acid_sequence
MQLKIMPKKKHLSAGGVPLILFLCQMISALDVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGTLVINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKERLEPIVLQNGQSLVLPCRPPIGLPPAIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISLKVISVDELNDTIAANLSDTEFYGAKSSKERPPTFLTPEGNESHKEELRGNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFYRNFKKTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISWLTNGVPIEIALDDPSRKIDGDTIIFSNVQESSSAVYQCNASNKYGYLLANAFVNVLAEPPRILTSANTLYQVIANRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPTIMWLKDNGELPNDERFSTDKDHLVVSDVKDDDGGTYTCTANTTLDSASASAVLRVVAPTPTPAPIYDVPNPPFDLELTNQLDKSVQLTWTPGDDNNSPITKFIIEYEDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAENSIGRSMPSEASEQYLTKAAEPDQNPMAVEGLGTEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTLAEVHWDPVPPKSVRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGEGPASTDRGFHTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYILQYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSVGPGSQITEEAITTVDEAGIPPPDVGAGKGKEEWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAEGDSGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV
uniprot
proteins
function
FUNCTION: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding (PubMed:11564762). Plays a role in mediating cell-cell contacts between Schwann cells and axons (PubMed:20188654). Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters (PubMed:14602817, PubMed:20188654). Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier (PubMed:24719088). {ECO:0000269|PubMed:11564762, ECO:0000269|PubMed:14602817, ECO:0000269|PubMed:16039564, ECO:0000269|PubMed:20188654, ECO:0000269|PubMed:24719088}.
uniprot
proteins
mass_dalton
138522
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
protein_family
L1/neurofascin/NgCAM family
uniprot
proteins
pubmed
11564762
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
14602817
uniprot
proteins
pubmed
16039564
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20188654
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23897819
uniprot
proteins
pubmed
24719088
uniprot
proteins
sequence_length
1256
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20188654}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, axon {ECO:0000269|PubMed:14602817}. Secreted {ECO:0000269|PubMed:20188654}. Note=Detected at nodes of Ranvier (PubMed:14602817, PubMed:20188654, PubMed:24719088). {ECO:0000269|PubMed:14602817, ECO:0000269|PubMed:20188654, ECO:0000269|PubMed:24719088}.
uniprot
proteins
transmembrane_region
TRANSMEM 1120..1142; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins