Cep97
entrez
74201
canonical
uniprot
Q9CZ62
canonical
ensembl
ENSMUSG00000022604
resolver
ensp
ENSMUSP00000023270
resolver
ensp
ENSMUSP00000112502
resolver
ensp
ENSMUSP00000113009
resolver
ensp
ENSMUSP00000113470
resolver
enst
ENSMUST00000121129
resolver
enst
ENSMUST00000121703
resolver
enst
ENSMUST00000122280
resolver
genesymbol
Cep97
resolver
genesymbol_syn
Lrriq2
resolver
uniprot
F6SVQ6
resolver
uniprot
F7B1V8
resolver
uniprot
F7C172
resolver
uniprot
Q6P077
resolver
uniprot
Q8BH46
resolver
uniprot
Q8BJR7
resolver
uniprot
Q8BL35
resolver
uniprot_entry
CEP97_MOUSE
resolver
uniprot_entry
F6SVQ6_MOUSE
resolver
uniprot_entry
F7B1V8_MOUSE
resolver
uniprot_entry
F7C172_MOUSE
resolver
uniprot_entry
Q6P077_MOUSE
resolver
uniprot_entry
Q8BH46_MOUSE
resolver
uniprot_entry
Q8BJR7_MOUSE
resolver
uniprot_sec
Q8BL35
resolver
amino_acid_sequence
MAVARVDGALAPGEGSVVNWSGQGLQKLGANLPCEADVHTLILDKNQIIKLENLEKCKQLIQLSVANNRLVRMMGVAKLTQLRVLNLPHNSIGCVEGLKDLVHLEWLNLAGNNLKTMEQVNSCTALQHLDLSDNNIPQIGDVSKLISLKTLLLHGNIITSLRMAPAYLPRNLSILSLAENEIRDLNEISFLASLSELEQLSIMNNPCVMATPSIPGFDYRPFIVSWCLNLRVLDGYVISQKESLKAEWLYSQGKGRSYRPGQHIQLVQYLATVCPLTSALGLQTAEDAKLEKILSKQRFHQRQLMSQSQDEELSPLAAVETRVHRTPECSSPGQDFQESEPVLQINSWVGISSNDDQLYAVKNNFPAAAHAARYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPVSPTVELRLQGINLGLEDDDGADEFTKGLENQDEDKDKEKSLWDMSESCVEMLKRKISTEVSEAAGLLPCPKSVIISAALKEDTHSLTSLPESAGHSASRTEANSEEAMSPATSEKFPCRILTQRPAALGQDKVTLQKLNAAATKLQACWRGFYTRNYNQQAKGVRYEIRLRRMQEHIVCLTDEVRRLRKERDEERVKTFVQEEAVRFLWNEVRSVQAWQQTVEQRLASWPPDVPPISSTLASPKPPLFPHHQDPSSDQSSDWLVAEDEAAQGRSAPDFPDSGFHSSLTEQVPCLQDSLDFEKSSVESSENSVLGNSADTVKCVKDRDSEATAEEHSDCSRESSASEQDNTLLQQYLTSVQQLDDAAEAADSDDVAGDGKRHLACSPERFDASSDSETHRVASTSQDEISQTPENCQLNEEAQGQPPECDPAFQGLHVGVTVQPV
uniprot
proteins
function
FUNCTION: Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome (By similarity). {ECO:0000250|UniProtKB:Q8IW35}.
uniprot
proteins
mass_dalton
94641
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the BCR(BACURD3) E3 ubiquitin ligase complex, at least composed of CUL3, KCTD10/BACURD3 and RBX1; leading to proteasomal degradation. {ECO:0000250|UniProtKB:Q8IW35}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30375385
uniprot
proteins
pubmed
35301795
uniprot
proteins
sequence_length
856
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:30375385}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q8IW35}. Note=Recruited at the distal end of the mother centriole by MPHOSPH9. {ECO:0000250|UniProtKB:Q8IW35}.
uniprot
proteins