ROPN1
entrez
54763
canonical
uniprot
Q9HAT0
canonical
ensembl
ENSG00000065371
resolver
ensp
ENSP00000184183
resolver
ensp
ENSP00000385919
resolver
genesymbol
ROPN1
resolver
genesymbol_syn
ROPN1A
resolver
hgnc
HGNC:17692
resolver
uniprot
A0A140VKB2
resolver
uniprot
D3DN99
resolver
uniprot
Q9UF38
resolver
uniprot_entry
A0A140VKB2_HUMAN
resolver
uniprot_entry
ROP1A_HUMAN
resolver
uniprot_sec
D3DN99
resolver
uniprot_sec
Q9UF38
resolver
amino_acid_sequence
MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVALCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHVSRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE
uniprot
proteins
function
FUNCTION: Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. {ECO:0000250|UniProtKB:Q9ESG2}.
uniprot
proteins
mass_dalton
23893
uniprot
proteins
post_translational_modification
PTM: Sumoylated, sumoylation decreases upon spermatozoa capacitation conditions. {ECO:0000250|UniProtKB:Q9ESG2}.
uniprot
proteins
protein_family
Ropporin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17551920
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
212
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9ESG2}. Note=In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath. {ECO:0000250|UniProtKB:Q9ESG2}.
uniprot
proteins