Naxe
entrez
295229
canonical
uniprot
B0BNM1
canonical
ensembl
ENSRNOG00000019201
resolver
ensembl
ENSRNOG00055023553
resolver
ensembl
ENSRNOG00060027132
resolver
ensembl
ENSRNOG00065030400
resolver
ensp
ENSRNOP00000025986
resolver
ensp
ENSRNOP00055032881
resolver
ensp
ENSRNOP00060039134
resolver
ensp
ENSRNOP00065043085
resolver
enst
ENSRNOT00000025986
resolver
enst
ENSRNOT00055040478
resolver
enst
ENSRNOT00060047051
resolver
enst
ENSRNOT00065052402
resolver
genesymbol
Naxe
resolver
genesymbol_syn
Aibp
resolver
genesymbol_syn
Apoa1bp
resolver
uniprot_entry
NNRE_RAT
resolver
amino_acid_sequence
MSGLRTLLGLGLLVAGSRLPRIASRQSVCRAGPIWWGTQHRSSETMASAAVKYLSQEEAQAVDEELFNEYQFSVDQLMELAGLSCATAIAKAYPPTSMSKSPPTVLVICGPGNNGGDGLVCARHLKLFGYQPTIYYPKRPNKPLFTGLVTQCQKMDIPFLGEMPPEPMMVDELYELVVDAIFGFSFKGDVREPFHSILSVLSGLTVPIASIDIPSGWDVEKGNPSGIQPDLLISLTAPKKSATQFTGRYHYLGGRFVPPALEKKYQLNLPAYPDTECVYRLQ
uniprot
proteins
ec_number
5.1.99.6
uniprot
proteins
function
FUNCTION: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis (By similarity). {ECO:0000250|UniProtKB:Q8NCW5, ECO:0000255|HAMAP-Rule:MF_03159}.
uniprot
proteins
mass_dalton
30891
uniprot
proteins
post_translational_modification
PTM: Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation. {ECO:0000255|HAMAP-Rule:MF_03159}.
uniprot
proteins
protein_family
NnrE/AIBP family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
282
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03159}. Secreted {ECO:0000255|HAMAP-Rule:MF_03159}. Note=In sperm, secretion gradually increases during capacitation. {ECO:0000255|HAMAP-Rule:MF_03159}.
uniprot
proteins