Gabrq
entrez
57249
canonical
uniprot
Q9JLF1
canonical
ensembl
ENSMUSG00000031344
resolver
ensp
ENSMUSP00000033711
resolver
ensp
ENSMUSP00000110200
resolver
enst
ENSMUST00000033711
resolver
enst
ENSMUST00000114553
resolver
genesymbol
Gabrq
resolver
uniprot
B1AUQ5
resolver
uniprot
Q0VEX8
resolver
uniprot
Q3TP00
resolver
uniprot_entry
B1AUQ5_MOUSE
resolver
uniprot_entry
GBRT_MOUSE
resolver
uniprot_entry
Q0VEX8_MOUSE
resolver
uniprot_entry
Q3TP00_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Potentiated by etomidate, propofol, pregnanolone and pentobarbital. {ECO:0000250|UniProtKB:Q9UN88}.
uniprot
proteins
amino_acid_sequence
MGIRGMLRAAALLLLIRTWLAESNGPSPTPKFHFELSSSTPEVILDLFNCKNCANEAVVQKILDRVLSTYDVRLRPNFGGAPVPVSVSIYVSSIEQISEINMDYTITMFLHQTWKDTRLAYYETNLNLTLDYRMHEKLWVPDCYFVNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLQKFPMDKQSCKLEVESYGYTVEDIVLSWEDDNAIHITDGLHIPQYTYLGRTITSKEVYFYTGSYMRLIVKFQVQREVRSYLVQVYWPTVLTTILSWISFWMNYDSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIKAIDIYILVCLFFVFLSLLEYVYINYLFFSQVPRRNHRRCRKPRRVVARYRYQEVVVANVQDGLINVEDRVEDRAGPLPDSPMQAHLASQESLGSLVFTSEQAQLATSESLSLLSSASSQTQLATGESLSDLPSTSEQTVPECTIHFHGFLTNDSIIPIKIHSRSDACDDEDSEESLSSEESHGHGSSHTGRLKLQISQRCVQEASWDLDKIEILQDDISITSSWLGLDEQCKGDADSIWSLTDEELMACDQEKDSSSESEENCSPSPGCSFNEGFSFQLFKPNRVPKVDRWSRFLFPLSFGLFNVVYWLYHVY
uniprot
proteins
function
FUNCTION: Theta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (By similarity). GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interfaces (By similarity). When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient (By similarity). {ECO:0000250|UniProtKB:P47870, ECO:0000250|UniProtKB:Q9UN88}.
uniprot
proteins
mass_dalton
72799
uniprot
proteins
protein_family
GABRQ sub-subfamily
uniprot
proteins
protein_family
Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily
uniprot
proteins
protein_family
Ligand-gated ion channel (TC 1.A.9) family
uniprot
proteins
pubmed
10804200
uniprot
proteins
sequence_length
638
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic cell membrane; Multi-pass membrane protein {ECO:0000255}. Cell membrane; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 268..288; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 297..314; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 326..346; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 618..638; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins