Septin6
entrez
56526
canonical
uniprot
Q9R1T4
canonical
ensembl
ENSMUSG00000050379
resolver
ensp
ENSMUSP00000054034
resolver
ensp
ENSMUSP00000062014
resolver
ensp
ENSMUSP00000110894
resolver
ensp
ENSMUSP00000314129
resolver
ensp
ENSMUSP00000314132
resolver
genesymbol
Septin6
resolver
genesymbol_syn
Kiaa0128
resolver
genesymbol_syn
Sept6
resolver
uniprot
A2A3V9
resolver
uniprot
A2A3W0
resolver
uniprot
Q3TRH9
resolver
uniprot
Q3TUA2
resolver
uniprot
Q542H3
resolver
uniprot
Q6A0C4
resolver
uniprot
Q8C2L2
resolver
uniprot
Q8C848
resolver
uniprot
Q91XH2
resolver
uniprot
Q9CZ94
resolver
uniprot_entry
SEPT6_MOUSE
resolver
uniprot_sec
A2A3V9
resolver
uniprot_sec
A2A3W0
resolver
uniprot_sec
Q3TRH9
resolver
uniprot_sec
Q3TUA2
resolver
uniprot_sec
Q542H3
resolver
uniprot_sec
Q6A0C4
resolver
uniprot_sec
Q8C2L2
resolver
uniprot_sec
Q8C848
resolver
uniprot_sec
Q91XH2
resolver
uniprot_sec
Q9CZ94
resolver
amino_acid_sequence
MAAADIARQVGEDCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPVIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDESVSEINGTMNAHLPFAVVGSTEEVKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQEEKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCIE
uniprot
proteins
function
FUNCTION: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). {ECO:0000250|UniProtKB:Q14141}.
uniprot
proteins
mass_dalton
49620
uniprot
proteins
protein_family
Septin GTPase family
uniprot
proteins
protein_family
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
uniprot
proteins
pubmed
11064363
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20181826
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25588830
uniprot
proteins
sequence_length
434
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore {ECO:0000250}. Cleavage furrow {ECO:0000250}. Midbody {ECO:0000250}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q14141}. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle. Expressed in the sperm annulus and head (PubMed:25588830). {ECO:0000250, ECO:0000250|UniProtKB:Q14141, ECO:0000269|PubMed:25588830}.
uniprot
proteins