Elp4
entrez
77766
canonical
uniprot
Q9ER73
canonical
ensembl
ENSMUSG00000027167
resolver
ensp
ENSMUSP00000116575
resolver
enst
ENSMUST00000122965
resolver
genesymbol
Elp4
resolver
genesymbol_syn
Paxneb
resolver
uniprot
Q8BGM1
resolver
uniprot
Q8BVB1
resolver
uniprot
Q8BZN8
resolver
uniprot
Q9CTR2
resolver
uniprot_entry
ELP4_MOUSE
resolver
uniprot_sec
Q8BGM1
resolver
uniprot_sec
Q8BVB1
resolver
uniprot_sec
Q8BZN8
resolver
uniprot_sec
Q9CTR2
resolver
amino_acid_sequence
MAAADTCGAGTLSSRSVASEAGQGGTSSFQRKGKASGGPGGGPRLLSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTLLLIEEDKYNIYSPLLFKYFMAEGIINGHTLLVASAKENPAKILQELPAPLLDDNSKKELEDVHSAKTPEPNVNMKIAWRYQLQPKMEVGPVSSSRFGHYYDLSKRIPWELLQSSKWHGFFLPEHISPDLKGESCFLSCGYMRLLEFIQKSVYAEGFDGANPQKKQKNILRIGIQNLGSPLWGDDICCKENCDNNHRLTKFLYILRGLLRSSLSACIITMPAHLVQNKSITTRVRNLSDTVVGLESFIGSERETNPLYKDYHGLIHIRKIPRLNNLTCDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVGRSSKQDLAASTARLGAGCSSMAEGKKHLDF
uniprot
proteins
function
FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. {ECO:0000250|UniProtKB:Q96EB1}.
uniprot
proteins
mass_dalton
46325
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. {ECO:0000250|UniProtKB:Q96EB1}.
uniprot
proteins
protein_family
ELP4 family
uniprot
proteins
pubmed
11889558
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30097576
uniprot
proteins
sequence_length
422
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96EB1}. Nucleus {ECO:0000250|UniProtKB:Q96EB1}.
uniprot
proteins