CIAO2A
entrez
84191
canonical
uniprot
Q9H5X1
canonical
ensembl
ENSG00000166797
resolver
ensp
ENSP00000300030
resolver
ensp
ENSP00000369644
resolver
ensp
ENSP00000454079
resolver
genesymbol
CIAO2A
resolver
genesymbol_syn
CIA2A
resolver
genesymbol_syn
FAM96A
resolver
hgnc
HGNC:26235
resolver
uniprot
A6NKS1
resolver
uniprot
B2R5F8
resolver
uniprot
B7Z8Z5
resolver
uniprot_entry
CIA2A_HUMAN
resolver
uniprot_sec
A6NKS1
resolver
uniprot_sec
B2R5F8
resolver
uniprot_sec
B7Z8Z5
resolver
amino_acid_sequence
MQRVSGLLSWTLSRVLWLSGLSEPGAARQPRIMEEKALEVYDLIRTIRDPEKPNTLEELEVVSESCVEVQEINEEEYLVIIRFTPTVPHCSLATLIGLCLRVKLQRCLPFKHKLEIYISEGTHSTEEDINKQINDKERVAAAMENPNLREIVEQCVLEPD
uniprot
proteins
function
FUNCTION: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). {ECO:0000250, ECO:0000269|PubMed:23891004, ECO:0000269|PubMed:25716227}.
uniprot
proteins
mass_dalton
18355
uniprot
proteins
protein_family
MIP18 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22683786
uniprot
proteins
pubmed
23891004
uniprot
proteins
pubmed
25716227
uniprot
proteins
pubmed
29320706
uniprot
proteins
sequence_length
160
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22683786}.
uniprot
proteins