SDSL
entrez
113675
canonical
uniprot
Q96GA7
canonical
ensembl
ENSG00000139410
resolver
ensp
ENSP00000341117
resolver
ensp
ENSP00000385790
resolver
ensp
ENSP00000544103
resolver
ensp
ENSP00000544104
resolver
ensp
ENSP00000544105
resolver
ensp
ENSP00000544106
resolver
ensp
ENSP00000544107
resolver
ensp
ENSP00000544109
resolver
ensp
ENSP00000544111
resolver
ensp
ENSP00000544112
resolver
ensp
ENSP00000544113
resolver
ensp
ENSP00000544114
resolver
ensp
ENSP00000544115
resolver
ensp
ENSP00000544116
resolver
ensp
ENSP00000544117
resolver
ensp
ENSP00000544118
resolver
ensp
ENSP00000544119
resolver
ensp
ENSP00000544121
resolver
ensp
ENSP00000544122
resolver
ensp
ENSP00000544123
resolver
ensp
ENSP00000634584
resolver
ensp
ENSP00000634585
resolver
ensp
ENSP00000634586
resolver
ensp
ENSP00000634587
resolver
enst
ENST00000345635
resolver
enst
ENST00000403593
resolver
enst
ENST00000874044
resolver
enst
ENST00000874045
resolver
enst
ENST00000874046
resolver
enst
ENST00000874047
resolver
enst
ENST00000874048
resolver
enst
ENST00000874050
resolver
enst
ENST00000874052
resolver
enst
ENST00000874053
resolver
enst
ENST00000874054
resolver
enst
ENST00000874055
resolver
enst
ENST00000874056
resolver
enst
ENST00000874057
resolver
enst
ENST00000874058
resolver
enst
ENST00000874059
resolver
enst
ENST00000874060
resolver
enst
ENST00000874062
resolver
enst
ENST00000874063
resolver
enst
ENST00000874064
resolver
enst
ENST00000964525
resolver
enst
ENST00000964526
resolver
enst
ENST00000964527
resolver
enst
ENST00000964528
resolver
genesymbol
SDSL
resolver
hgnc
HGNC:30404
resolver
uniprot_entry
SDSL_HUMAN
resolver
amino_acid_sequence
MDGPVAEHAKQEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQEMAKKGCRHLVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLRAQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLEVGWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIHSEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIVCGGNNINSRELQALKTHLGQV
uniprot
proteins
ec_number
4.3.1.17
uniprot
proteins
ec_number
4.3.1.19
uniprot
proteins
ec_number
5.1.1.3
uniprot
proteins
function
FUNCTION: Catalyzes the pyridoxal-phosphate-dependent dehydrative deamination of L-threonine and L-serine to ammonia and alpha-ketobutyrate and pyruvate, respectively (PubMed:16580895, PubMed:18342636). Also exhibits racemase activity towards L-glutamate and D-glutamate (By similarity). {ECO:0000250|UniProtKB:A0A6N3IN21, ECO:0000269|PubMed:16580895, ECO:0000269|PubMed:18342636}.
uniprot
proteins
mass_dalton
34674
uniprot
proteins
mutagenesis
MUTAGEN 72; /note="G->A: Strongly increased enzyme activity towards threonine."; /evidence="ECO:0000269|PubMed:18342636"; MUTAGEN 287; /note="L->V: Almost no change in Km and Vmax for serine and threonine. Significantly increased protein levels."; /evidence="ECO:0000269|PubMed:16580895"; MUTAGEN 309; /note="C->A: Loss of enzyme activity."; /evidence="ECO:0000269|PubMed:18342636
uniprot
proteins
protein_family
Serine/threonine dehydratase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16580895
uniprot
proteins
pubmed
18342636
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
329
uniprot
proteins