Kcnh7
entrez
170738
canonical
uniprot
Q9ER47
canonical
ensembl
ENSMUSG00000059742
resolver
ensp
ENSMUSP00000074563
resolver
ensp
ENSMUSP00000108073
resolver
enst
ENSMUST00000075052
resolver
genesymbol
Kcnh7
resolver
genesymbol_syn
Erg3
resolver
uniprot
A2AUY8
resolver
uniprot_entry
KCNH7_MOUSE
resolver
uniprot_sec
A2AUY8
resolver
amino_acid_sequence
MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENAATPERVNPILPVKTVNRKLFGFKFPGLRVLTYRKQSLPQEDPDVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSQCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLTHSRSRESLCSIRRASSVHDIEGFSVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDVKTEKKNTSPPSSDKTIIAPKVKERTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGTQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKSQSVNDSEGDTGKLRRRRLSFESEGEKDFSKENSANDADDSTDTIRRYQSSKKHFEERKSRSSSFISSIDDEQKPLFLGTVDSTPRMVKATRLHGEETMPHSGRIHTEKRSHSCRDITDTHSWEREPARAQPEECSPSGLQRAAWGVSETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQAILQLLQKQTTVVPPAYSMVTAGAEYQRPILRLLRTSHPRASIKTDRSFSPSSQCPEFLDLEKSKLQSKESLSSGRRLNTASEDNLTSLLKQDSDASSELDPRQRKTYLHPIRHPSLPDSSLSTVGILGLHRHVSDPGLPGK
uniprot
proteins
function
FUNCTION: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Exhibits faster activation and deactivation kinetics and slow inactivation at membrane potentials positive to 240 mV, resulting in the weakest inward rectification. {ECO:0000250|UniProtKB:O54852}.
uniprot
proteins
mass_dalton
135062
uniprot
proteins
protein_family
H (Eag) (TC 1.A.1.20) subfamily
uniprot
proteins
protein_family
Kv11.3/KCNH7 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1195
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q12809}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q12809}.
uniprot
proteins
transmembrane_region
TRANSMEM 413..433; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 450..470; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 495..515; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 522..542; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 550..570; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 642..662; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins