Spag16
entrez
66722
canonical
uniprot
Q8K450
canonical
ensembl
ENSMUSG00000053153
resolver
ensp
ENSMUSP00000069821
resolver
ensp
ENSMUSP00000109573
resolver
ensp
ENSMUSP00000171051
resolver
genesymbol
Spag16
resolver
genesymbol_syn
Pf20
resolver
uniprot
Q0VBE7
resolver
uniprot
Q8C450
resolver
uniprot
Q9CPU8
resolver
uniprot
Q9D522
resolver
uniprot_entry
SPG16_MOUSE
resolver
uniprot_sec
Q0VBE7
resolver
uniprot_sec
Q8C450
resolver
uniprot_sec
Q9CPU8
resolver
uniprot_sec
Q9D522
resolver
amino_acid_sequence
MAAPSGVPPLRVLEELGIGLSPTGEVTEAVTSEGAYYLEQVTITETSEDECEYEEIPDDNFSIPEGEEDLEKAIHIIGEQARDIHILEQQTILPARNVMQEAIEDFLCNFLIKMGMTRTLDCFQAEWYELIQKKGSDFKGLGNVPDVYSQVMLLETENKNLKKELKHFKQAAEKAKEDLLRTQKERDFHRMHHKRIVQEKNKLIADLKGLKLHYASYEPTIRVLHEKHHALLKEKMLTSLERDRAVGKISGLQATLKNIDMGHIQVPVIKGSYESASITRESGDRAGHSCEKENSSEGPTQKSLREAREEVGYKSKLKNEKKDSEFPVDMQPDPNVTSCTENVSAAKFDYKLNNIFRLHELPVSCIVMHPCRDYLISCSEDRLWKMVGLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLNKGECTLTLEGHNHAVWSCTWHSCGDFVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSLYGHMHSVNDATFTPRGHIIASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFDQSGRVLAQASANGIIHLLDLKSGQIHKLVGHESEVHSVVFSHLGENLYSGGSDGTIRLWI
uniprot
proteins
function
FUNCTION: Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia. {ECO:0000269|PubMed:19305393}.
uniprot
proteins
mass_dalton
71473
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by TSSK2. {ECO:0000305|PubMed:18367677}.
uniprot
proteins
pubmed
12391165
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18367677
uniprot
proteins
pubmed
19305393
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27682589
uniprot
proteins
pubmed
39853433
uniprot
proteins
sequence_length
639
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12391165}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:12391165}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:12391165}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:12391165, ECO:0000269|PubMed:27682589}. Note=Detected on the sperm flagellum. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules. {ECO:0000269|PubMed:12391165, ECO:0000269|PubMed:27682589}.
uniprot
proteins