PPP3R1
entrez
5534
canonical
uniprot
P63098
canonical
ensembl
ENSG00000221823
resolver
ensp
ENSP00000234310
resolver
enst
ENST00000234310
resolver
genesymbol
PPP3R1
resolver
genesymbol_syn
CNA2
resolver
genesymbol_syn
CNB
resolver
hgnc
HGNC:9317
resolver
uniprot
B2RC10
resolver
uniprot
B5MDU4
resolver
uniprot
P06705
resolver
uniprot
P15117
resolver
uniprot
Q08044
resolver
uniprot
Q53SL0
resolver
uniprot_entry
CANB1_HUMAN
resolver
uniprot_sec
B2RC10
resolver
uniprot_sec
B5MDU4
resolver
uniprot_sec
P06705
resolver
uniprot_sec
P15117
resolver
uniprot_sec
Q08044
resolver
uniprot_sec
Q53SL0
resolver
amino_acid_sequence
MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
uniprot
proteins
function
FUNCTION: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. {ECO:0000269|PubMed:26794871}.
uniprot
proteins
mass_dalton
19300
uniprot
proteins
protein_family
Calcineurin regulatory subunit family
uniprot
proteins
pubmed
12218175
uniprot
proteins
pubmed
12357034
uniprot
proteins
pubmed
12809556
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17498738
uniprot
proteins
pubmed
22343722
uniprot
proteins
pubmed
23468591
uniprot
proteins
pubmed
25255805
uniprot
proteins
pubmed
2558868
uniprot
proteins
pubmed
26794871
uniprot
proteins
pubmed
27974827
uniprot
proteins
pubmed
31375679
uniprot
proteins
pubmed
34446558
uniprot
proteins
pubmed
8524402
uniprot
proteins
sequence_length
170
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q63810}. Cell membrane {ECO:0000250|UniProtKB:Q63810}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q63810}. Cell membrane {ECO:0000269|PubMed:25255805}; Lipid-anchor {ECO:0000269|PubMed:25255805}. Note=Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. {ECO:0000250|UniProtKB:Q63810}.
uniprot
proteins