RNASE4
entrez
6038
canonical
uniprot
P34096
canonical
ensembl
ENSG00000258818
resolver
ensp
ENSP00000381081
resolver
ensp
ENSP00000451624
resolver
ensp
ENSP00000452245
resolver
ensp
ENSP00000555425
resolver
ensp
ENSP00000555426
resolver
ensp
ENSP00000555427
resolver
ensp
ENSP00000555428
resolver
ensp
ENSP00000555429
resolver
ensp
ENSP00000555430
resolver
ensp
ENSP00000555431
resolver
ensp
ENSP00000555432
resolver
ensp
ENSP00000555433
resolver
ensp
ENSP00000555434
resolver
ensp
ENSP00000555435
resolver
ensp
ENSP00000555436
resolver
ensp
ENSP00000555437
resolver
ensp
ENSP00000555438
resolver
ensp
ENSP00000641334
resolver
ensp
ENSP00000641335
resolver
enst
ENST00000397995
resolver
enst
ENST00000555597
resolver
enst
ENST00000555835
resolver
enst
ENST00000885366
resolver
enst
ENST00000885367
resolver
enst
ENST00000885368
resolver
enst
ENST00000885369
resolver
enst
ENST00000885370
resolver
enst
ENST00000885371
resolver
enst
ENST00000885372
resolver
enst
ENST00000885373
resolver
enst
ENST00000885374
resolver
enst
ENST00000885375
resolver
enst
ENST00000885376
resolver
enst
ENST00000885377
resolver
enst
ENST00000885378
resolver
enst
ENST00000885379
resolver
enst
ENST00000971275
resolver
enst
ENST00000971276
resolver
genesymbol
RNASE4
resolver
genesymbol_syn
RNS4
resolver
hgnc
HGNC:10047
resolver
uniprot
Q53XB4
resolver
uniprot_entry
Q53XB4_HUMAN
resolver
uniprot_entry
RNAS4_HUMAN
resolver
amino_acid_sequence
MALQRTHSLLLLLLLTLLGLGLVQPSYGQDGMYQRFLRQHVHPEETGGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDIWNIRSICSTTNIQCKNGKMNCHEGVVKVTDCRDTGSSRAPNCRYRAIASTRRVVIACEGNPQVPVHFDG
uniprot
proteins
ec_number
3.1.27.-
uniprot
proteins
function
FUNCTION: Cleaves preferentially after uridine bases (PubMed:3467790). Has antimicrobial activity against uropathogenic E.coli (UPEC) (PubMed:33818125). Probably contributes to urinary tract sterility (PubMed:33818125). {ECO:0000269|PubMed:33818125, ECO:0000269|PubMed:3467790}.
uniprot
proteins
mass_dalton
16840
uniprot
proteins
protein_family
Pancreatic ribonuclease family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
30418175
uniprot
proteins
pubmed
33818125
uniprot
proteins
pubmed
3467790
uniprot
proteins
pubmed
7501448
uniprot
proteins
pubmed
7742370
uniprot
proteins
pubmed
8223579
uniprot
proteins
pubmed
9878400
uniprot
proteins
sequence_length
147
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:33818125}. Note=Detected in urine. {ECO:0000269|PubMed:33818125}.
uniprot
proteins