GPR137C
entrez
283554
canonical
uniprot
Q8N3F9
canonical
ensembl
ENSG00000180998
resolver
ensp
ENSP00000315106
resolver
ensp
ENSP00000439165
resolver
enst
ENST00000321662
resolver
genesymbol
GPR137C
resolver
genesymbol_syn
TM7SF1L2
resolver
hgnc
HGNC:25445
resolver
uniprot
B3KW22
resolver
uniprot
Q86SM2
resolver
uniprot_entry
B3KW22_HUMAN
resolver
uniprot_entry
G137C_HUMAN
resolver
uniprot_sec
Q86SM2
resolver
amino_acid_sequence
MRVSVPGPAAAAAPAAGREPSTPGGGSGGGGAVAAASGAAVPGSVQLALSVLHALLYAALFAFAYLQLWRLLLYRERRLSYQSLCLFLCLLWAALRTTLFSAAFSLSGSLPLLRPPAHLHFFPHWLLYCFPSCLQFSTLCLLNLYLAEVICKVRCATELDRHKILLHLGFIMASLLFLVVNLTCAMLVHGDVPENQLKWTVFVRALINDSLFILCAISLVCYICKITKMSSANVYLESKGMSLCQTVVVGSVVILLYSSRACYNLVVVTISQDTLESPFNYGWDNLSDKAHVEDISGEEYIVFGMVLFLWEHVPAWSVVLFFRAQRLNQNLAPAGMINSHSYSSRAYFFDNPRRYDSDDDLPRLGSSREGSLPNSQSLGWYGTMTGCGSSSYTVTPHLNGPMTDTAPLLFTCSNLDLNNHHSLYVTPQN
uniprot
proteins
function
FUNCTION: Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. {ECO:0000269|PubMed:31036939}.
uniprot
proteins
mass_dalton
47075
uniprot
proteins
protein_family
GPR137 family
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
12679517
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
31036939
uniprot
proteins
sequence_length
429
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000269|PubMed:31036939}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 49..69; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 84..104; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 121..141; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 168..188; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 206..226; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 247..267; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 301..321; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins