Mcmbp
entrez
309009
canonical
uniprot
B1H268
canonical
ensembl
ENSRNOG00000020394
resolver
ensembl
ENSRNOG00055028016
resolver
ensembl
ENSRNOG00060027141
resolver
ensembl
ENSRNOG00065016095
resolver
ensp
ENSRNOP00000027644
resolver
ensp
ENSRNOP00055039868
resolver
ensp
ENSRNOP00060039212
resolver
ensp
ENSRNOP00065021022
resolver
enst
ENSRNOT00000027644
resolver
enst
ENSRNOT00055048502
resolver
enst
ENSRNOT00060047139
resolver
enst
ENSRNOT00065026776
resolver
genesymbol
Mcmbp
resolver
uniprot_entry
MCMBP_RAT
resolver
amino_acid_sequence
MPCGEDWLSHPLGIVQGFFAQNGVTPDWEKKVIDYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQNTKARVLHFGKYRDVAECGPQQELDLNSPRSTTSERQTFYCVPVPGESLWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHSGARQAGGLGGLHWRGEPKRLETEASSGQQLNSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPILSILNNEERDASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRTCQFVSNFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKLIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTPGVHNVAALSNLITWQKVDYDFSYHQMEFPCNINVLITSEGRSLLPADCQIHLQPQLIPPNMEEYMNGLLSAVLPSVLNKFRIYLTLLRFLDYNLSDDITKAVEDDFVEMRKNDPQSITADDLHQLLVVARFLSLSAGQTTLSRERWLRAKQLEHSRRSRLQQQKSVNGNEL
uniprot
proteins
function
FUNCTION: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
73007
uniprot
proteins
protein_family
MCMBP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
642
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex (By similarity). {ECO:0000250}.
uniprot
proteins