PEA15
entrez
8682
canonical
uniprot
Q15121
canonical
ensembl
ENSG00000162734
resolver
ensp
ENSP00000353660
resolver
ensp
ENSP00000357055
resolver
ensp
ENSP00000357056
resolver
ensp
ENSP00000523743
resolver
ensp
ENSP00000523753
resolver
ensp
ENSP00000523756
resolver
enst
ENST00000368077
resolver
enst
ENST00000853695
resolver
enst
ENST00000853697
resolver
genesymbol
PEA15
resolver
hgnc
HGNC:8822
resolver
uniprot
B1AKZ3
resolver
uniprot
B1AKZ4
resolver
uniprot
B1AKZ5
resolver
uniprot
D3DVE5
resolver
uniprot
O00511
resolver
uniprot
Q96FS5
resolver
uniprot_entry
B1AKZ4_HUMAN
resolver
uniprot_entry
B1AKZ5_HUMAN
resolver
uniprot_entry
PEA15_HUMAN
resolver
uniprot_entry
Q96FS5_HUMAN
resolver
uniprot_sec
B1AKZ3
resolver
uniprot_sec
D3DVE5
resolver
uniprot_sec
O00511
resolver
amino_acid_sequence
MAEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIFEISRRPDLLTMVVDYRTRVLKISEEDELDTKLTRIPSAKKYKDIIRQPSEEEIIKLAPPPKKA
uniprot
proteins
function
FUNCTION: Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. {ECO:0000250, ECO:0000269|PubMed:10442631, ECO:0000269|PubMed:9670003}.
uniprot
proteins
mass_dalton
15040
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by protein kinase C and calcium-calmodulin-dependent protein kinase. These phosphorylation events are modulated by neurotransmitters or hormones.
uniprot
proteins
pubmed
10442631
uniprot
proteins
pubmed
10607908
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8662970
uniprot
proteins
pubmed
9670003
uniprot
proteins
sequence_length
130
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with microtubules.
uniprot
proteins