PPP1R3B
entrez
79660
canonical
uniprot
Q86XI6
canonical
ensembl
ENSG00000173281
resolver
ensembl
ENSG00000285343
resolver
ensp
ENSP00000308318
resolver
ensp
ENSP00000428642
resolver
ensp
ENSP00000493491
resolver
ensp
ENSP00000494659
resolver
enst
ENST00000310455
resolver
enst
ENST00000519699
resolver
enst
ENST00000644687
resolver
enst
ENST00000645121
resolver
genesymbol
PPP1R3B
resolver
genesymbol_syn
PPP1R4
resolver
hgnc
HGNC:14942
resolver
uniprot
B3KTV3
resolver
uniprot
Q9H812
resolver
uniprot_entry
PPR3B_HUMAN
resolver
uniprot_sec
B3KTV3
resolver
uniprot_sec
Q9H812
resolver
amino_acid_sequence
MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY
uniprot
proteins
function
FUNCTION: Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
32695
uniprot
proteins
pubmed
11872655
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17555403
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
285
uniprot
proteins