Nuggc
entrez
100503545
canonical
uniprot
D3YWJ0
canonical
ensembl
ENSMUSG00000061356
resolver
ensp
ENSMUSP00000078434
resolver
ensp
ENSMUSP00000118402
resolver
enst
ENSMUST00000079469
resolver
enst
ENSMUST00000150897
resolver
genesymbol
Nuggc
resolver
genesymbol_syn
Gm600
resolver
uniprot
D3YY21
resolver
uniprot_entry
D3YY21_MOUSE
resolver
uniprot_entry
SLIP_MOUSE
resolver
amino_acid_sequence
MEEMEALVGVVPHSADCDLFKEPVRKRRRLHRDRQFQAFPSAEQSALKEYEKLECRTRRVLSNTYQKLIQSVFLDDSIPSGLKYLINRLLALIEKSPLEPVYVGFLGITGAGKSSLINALIRQAMFLPVSGESVCTSCIVQVSSGCCEQYEAKIHLLSDQEWKAELKDLTKLLHRAEQSGEEEADLWDRDDATEEAAQKLRMLYGHGAERRHYEELLRLKPRGRIPNSRTITLKAEEAGELSVKLDPYIRTRRRDWDGESAETQIWPLIKYVEVILPKSALIPEGVVLVDIPGTGDFNSKRDKMWKKTIDKCSVIWVISDIERVSGGKTHEDLLSESIKACQRGFCRDIALVVTKTDKLHLQEYLRERKMGNQAIQSQREAVLQRNEIIKLQRKRMLKEKLKRKLPADSKVLEASDLVYTVSAHEYWQRTILTEEESEIPKLREYIRKRILDKKRRLVTKYVTEAFGLLLLTDTLNTEESLLTEELNTGGLRQFVEEKMELLEKAIEQCFARMEQPLQTGVQVAMTSYRRILGSCLVRSRGNQGFHQTLKAVCLKNGVYASRTLARIDLNEALSQPIYDQIDPVFGGIFRDGKPTAPALMQHIDAFKHSLEERMAEVGVRSGWKQDGYKRSFLIQEISAILGGLESHILRRKRKIYKSVTSSIQNDLKPCYEEAAQITGKKACERMKDVIRRGVERQVAEGLFERAQERMWHQFRQLKHGITEKVKGSITTMLTLAAPQGVGLCKELADVRNEQKEMEKLYRSLREVAENAQLRRSMQDFLLRMSPSKAGPHGTKL
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
function
FUNCTION: Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (By similarity). Reduces somatic hypermutation in B-cells which may enhance genome stability (PubMed:22833677). {ECO:0000250|UniProtKB:Q68CJ6, ECO:0000269|PubMed:22833677}.
uniprot
proteins
mass_dalton
91269
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22833677
uniprot
proteins
sequence_length
796
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000269|PubMed:22833677}.
uniprot
proteins