HAUS8
entrez
93323
canonical
uniprot
Q9BT25
canonical
ensembl
ENSG00000131351
resolver
ensp
ENSP00000253669
resolver
ensp
ENSP00000395298
resolver
genesymbol
HAUS8
resolver
genesymbol_syn
HICE1
resolver
hgnc
HGNC:30532
resolver
uniprot
B4DJA7
resolver
uniprot
C9JBZ4
resolver
uniprot
Q49AC4
resolver
uniprot
Q86WF0
resolver
uniprot
Q96FX3
resolver
uniprot_entry
HAUS8_HUMAN
resolver
uniprot_sec
B4DJA7
resolver
uniprot_sec
C9JBZ4
resolver
uniprot_sec
Q49AC4
resolver
uniprot_sec
Q86WF0
resolver
uniprot_sec
Q96FX3
resolver
amino_acid_sequence
MADSSGRGAGKPATGPTNSSSAKKKDKRVQGGRVIESRYLQYEKKTTQKAPAGDGSQTRGKMSEGGRKSSLLQKSKADSSGVGKGDLQSTLLEGHGTAPPDLDLSAINDKSIVKKTPQLAKTISKKPESTSFSAPRKKSPDLSEAMEMMESQTLLLTLLSVKMENNLAEFERRAEKNLLIMCKEKEKLQKKAHELKRRLLLSQRKRELADVLDAQIEMLSPFEAVATRFKEQYRTFATALDTTRHELPVRSIHLEGDGQQLLDALQHELVTTQRLLGELDVGDSEENVQVLDLLSELKDVTAKKDLELRRSFAQVLELSAEASKEAALANQEVWEETQGMAPPSRWYFNQDSACRESGGAPKNTPLSEDDNPGASSAPAQATFISPSEDFSSSSQAEVPPSLSRSGRDLS
uniprot
proteins
function
FUNCTION: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269|PubMed:18362163, ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.
uniprot
proteins
mass_dalton
44857
uniprot
proteins
protein_family
HAUS8 family
uniprot
proteins
pubmed
12601173
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18362163
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19369198
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19427217
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
30723163
uniprot
proteins
sequence_length
410
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000305|PubMed:19369198}. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively. Localizes to mitotic spindle microtubules. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217, ECO:0000269|PubMed:30723163}.
uniprot
proteins