Armc9
entrez
78795
canonical
uniprot
Q9D2I5
canonical
ensembl
ENSMUSG00000062590
resolver
ensp
ENSMUSP00000027434
resolver
ensp
ENSMUSP00000108934
resolver
ensp
ENSMUSP00000117267
resolver
ensp
ENSMUSP00000209961
resolver
ensp
ENSMUSP00000209962
resolver
ensp
ENSMUSP00000209966
resolver
ensp
ENSMUSP00000209967
resolver
ensp
ENSMUSP00000210016
resolver
ensp
ENSMUSP00000348079
resolver
ensp
ENSMUSP00000348080
resolver
genesymbol
Armc9
resolver
uniprot
Q8BQQ3
resolver
uniprot
Q8BR45
resolver
uniprot
Q8BSX7
resolver
uniprot
Q8C6A6
resolver
uniprot
Q8C889
resolver
uniprot
Q8CA23
resolver
uniprot
Q8CBG2
resolver
uniprot
Q8K112
resolver
uniprot
Q9CYL1
resolver
uniprot
Q9D2L3
resolver
uniprot_entry
ARMC9_MOUSE
resolver
uniprot_sec
Q8BQQ3
resolver
uniprot_sec
Q8BR45
resolver
uniprot_sec
Q8BSX7
resolver
uniprot_sec
Q8C6A6
resolver
uniprot_sec
Q8C889
resolver
uniprot_sec
Q8CA23
resolver
uniprot_sec
Q8CBG2
resolver
uniprot_sec
Q8K112
resolver
uniprot_sec
Q9CYL1
resolver
uniprot_sec
Q9D2L3
resolver
amino_acid_sequence
MGDILAHESELLGLVKEYLDFAEFEDTLKTFSKECKVKGKPLCKNVGGPLKKDSKSLVIQRDLVAAFDSGDQKAFFDLWEGHIPSSVRDTDSLAQKLEFYLHIHFAIYLLKYCRGRPDKQELDKRISYFKTYLETKGAALSQTTEFLPFYALPFVPNPMVHPSFKELFQDSWTPELKLKLEKFLALTFKANNTPKLLTIYKENGPNSKELLQQLHQQLVEAERRAMTYLKRYNKIQADYHNLIGVTAELVDSLEATVSGKMITPEYLQSVCVRLFSNQMRQSLAHSVDFTRPGTASTMLRASLAPEKLKDVPLLPSLDYEKLKKDLIWGSDRLKAFLLQALRWRLTTSHPGEQRETVLQAYISNDLLDCHSHNQRSVLQLLHSKSEAVRQYMARLINALASLAEGRLYLAQNTKVLRMLEGRLKEEDKDVITRENVLGALQKFSLRRPLQTAMIRDGLIFWLIDLLKDPDCLSDYTLEYSVALLMNLCLRSAGKNMCAKVAGLMLKVLSDLLGHENHEIQPYVNGALYSILSIPSIREEARAMGMEDILRCFIKEGNAEMIRQIEFIIKQLNSEDLLDGVLESDDDEDEDDEEDHDIMEADLDKDELIQPQLGELSGEKLLTTEYLGIMTNTGKARRKGPASVQWSGDEPLRRPVTPGGHRTGCPVLGDHLISPQNAQQARNGCLRAMPVAHPDDYKEGKPGVTGCGTSSSFMDHKPREWSPAGHQKSRLVPTAALGWPREMTQDPSSGHITREFVPAFTCKPQVPSTPETVEQNPLKAKALSLAPQFSSSGPQQASRPASTASSTRGLHSSQSIRK
uniprot
proteins
function
FUNCTION: Involved in ciliogenesis (By similarity). It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (By similarity). Acts as a positive regulator of hedgehog (Hh) signaling (PubMed:29459677). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (PubMed:29459677). {ECO:0000250|UniProtKB:E7F187, ECO:0000250|UniProtKB:Q7Z3E5, ECO:0000269|PubMed:29459677}.
uniprot
proteins
mass_dalton
91922
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29459677
uniprot
proteins
sequence_length
817
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q7Z3E5}. Cell projection, cilium {ECO:0000269|PubMed:29459677}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q7Z3E5}. Note=Localized to the proximal region in cilia. Stimulation of Hh signaling leads to redistribution of ARMC9 toward the ciliary tip within 6 hours, follow by a gradual return to its original proximal location (PubMed:29459677). Localizes to the daughter centriole of the primary cilium in RPE1 cells (By similarity). {ECO:0000250|UniProtKB:Q7Z3E5, ECO:0000269|PubMed:29459677}.
uniprot
proteins