Cenpi
entrez
25448
canonical
uniprot
Q63517
canonical
ensembl
ENSRNOG00000033335
resolver
ensp
ENSRNOP00000041317
resolver
enst
ENSRNOT00000046288
resolver
genesymbol
Cenpi
resolver
genesymbol_syn
Fshprh1
resolver
genesymbol_syn
Lrpr1
resolver
uniprot
F1LP20
resolver
uniprot_entry
CENPI_RAT
resolver
uniprot_entry
F1LP20_RAT
resolver
amino_acid_sequence
MATPRLTRNSQQQNRISQGSNSRQTTLLDWKVKDKAGNSKSVLEESSSLEDSNHADDQTEDALQTAVEYFQKGPKKASLSKDSVLEKHLKTVENVAWNNGLAPEAIDILLNVALSGKFGNALSTRILKCMIPETHISEDSVVKAVSWLCVGKCSGNTKVLFYRWLVAMFDFIDHKKQINSLYGFFFVSLQDDTLCPYVCHLLYLLTKKENVKPFRARKLLDLQAKMGMQPHLQALLSLYKFFAPTLISVSLPVRKKIFFNNSKNLWTPALLAVKLRNQGIFPEPLKLQLGPTSGRSLKRKWNYHSVIPAVNSAKKECREKMSLFDYLSNDRSLPVEQLQSFPQLLENIHCLELPSQMSSVLNSSLLLHYVNCVKDESILLRLSYWLSQTLQEECVWYNMNDYQQEKEFINFLDMVIRVQCFLQEGFYSCEAFLYKSLPLWDGFSCRSQFLKLLAWIPFSSFSEIKPLLLDHLAPLFFTSSIYFKCSLLQCLKDLLQNWLLWLSTEAQVQPMTDSPLETTLGGSMDSVSQLIEYIGWLSMVAIRLESSSTLLVHFILDFYEKVCDIYINYDLPLVVLFPPVVFHSAFLSLDATILNQLCYIMYRYRDNLTAAKKKDLVQKAKSEFSISSKICKEFNYYLTALVHCLWSSRPFETGVYIDPQIIENTGETQYKHNLNFVHHPCLLNYAASFLLQESPEEMPVHLSSIRGKKWNWYLDHLYSEGFQGLNLFIKSSIDHSSVSKTEKNT
uniprot
proteins
function
FUNCTION: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
85651
uniprot
proteins
post_translational_modification
PTM: Sumoylated. Sumoylated form can be polyubiquitinated by RNF4, leading to its degradation. Desumoylation by SENP6 prevents its degradation (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
CENP-I/CTF3 family
uniprot
proteins
pubmed
7758824
uniprot
proteins
sequence_length
745
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere {ECO:0000250}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex (By similarity). {ECO:0000250}.
uniprot
proteins