Entr1
entrez
68112
canonical
uniprot
A2AIW0
canonical
ensembl
ENSMUSG00000026927
resolver
ensp
ENSMUSP00000028293
resolver
ensp
ENSMUSP00000077133
resolver
ensp
ENSMUSP00000109735
resolver
ensp
ENSMUSP00000109737
resolver
ensp
ENSMUSP00000318719
resolver
ensp
ENSMUSP00000318731
resolver
enst
ENSMUST00000114100
resolver
genesymbol
Entr1
resolver
genesymbol_syn
Sdccag3
resolver
uniprot
A2AIW1
resolver
uniprot
A2AIW3
resolver
uniprot
Q3TQC5
resolver
uniprot
Q6P8W2
resolver
uniprot
Q8BIV5
resolver
uniprot
Q8K0I8
resolver
uniprot
Q9D1V2
resolver
uniprot
Q9D4S1
resolver
uniprot
Q9D5W1
resolver
uniprot_entry
A2AIW3_MOUSE
resolver
uniprot_entry
ENTR1_MOUSE
resolver
uniprot_sec
A2AIW1
resolver
uniprot_sec
Q3TQC5
resolver
uniprot_sec
Q6P8W2
resolver
uniprot_sec
Q8BIV5
resolver
uniprot_sec
Q8K0I8
resolver
uniprot_sec
Q9D1V2
resolver
uniprot_sec
Q9D4S1
resolver
uniprot_sec
Q9D5W1
resolver
amino_acid_sequence
MSGYARRQGAPPLSRTRSLVVPDAPAFYERRSCLPQLDCERPHGGDLHPHLFGFRPTFMCYVPSPVLASVGDTGFGYGKGKCTNQGPSGAPETRFGGDKLEDLEEANPFSFKEFLKTKNLSLSKEDTTTSRIYPKEASRHPLGLEHSSPASQLMGYGLESQQPFFEDPTRASNLEEDEDDGWNITYLPSAVDQTHSSRDTQDSPPCDTYLSFFSNSSELACPESLPPWTLSDTDSRISPASPAGSPNADFAAHEESLGDRHLRTLQISYEALKDENSKLRRKLNEVQSFSETQTEMVRTLERKLEAKMIKEESDFHDLESVVQQVEQNLELMTKRAVKAENHVLKLKQEINLLQAQLSNLRRENEALRSGQGASLSVVKQNTDVALQNLHLVMNSAHASIKQLVSGADTLNLVAEILKSIDRISEVKDEVDS
uniprot
proteins
function
FUNCTION: May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface (PubMed:16332174). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 (By similarity). {ECO:0000250|UniProtKB:Q96C92, ECO:0000269|PubMed:16332174}.; FUNCTION: Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia (By similarity). Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis (PubMed:16332174). {ECO:0000250|UniProtKB:Q96C92, ECO:0000269|PubMed:16332174}.
uniprot
proteins
mass_dalton
48025
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250|UniProtKB:Q96C92}.
uniprot
proteins
protein_family
ENTR1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16332174
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23108400
uniprot
proteins
sequence_length
432
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16332174}. Early endosome {ECO:0000250|UniProtKB:Q96C92}. Endosome {ECO:0000250|UniProtKB:Q96C92}. Recycling endosome {ECO:0000250|UniProtKB:Q96C92}. Midbody {ECO:0000250|UniProtKB:Q96C92}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q96C92}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q96C92}. Note=Colocalizes in a WASHC2-dependent manner with the retromer CSC complex at endosomes. During cytokinesis colocalized with PTPN13 at the midbody. Colocalizes with IFT88 and gamma-tubulin at the basal body of primary cilia. Colocalizes with IFT88 and pericentrin at the centrosome. {ECO:0000250|UniProtKB:Q96C92}.
uniprot
proteins