Sorbs2
entrez
234214
canonical
uniprot
Q3UTJ2
canonical
ensembl
ENSMUSG00000031626
resolver
ensp
ENSMUSP00000067641
resolver
ensp
ENSMUSP00000114286
resolver
ensp
ENSMUSP00000121235
resolver
ensp
ENSMUSP00000121619
resolver
ensp
ENSMUSP00000123250
resolver
ensp
ENSMUSP00000128000
resolver
ensp
ENSMUSP00000308905
resolver
ensp
ENSMUSP00000308907
resolver
ensp
ENSMUSP00000308917
resolver
ensp
ENSMUSP00000308920
resolver
ensp
ENSMUSP00000308925
resolver
ensp
ENSMUSP00000308926
resolver
ensp
ENSMUSP00000308929
resolver
ensp
ENSMUSP00000308940
resolver
ensp
ENSMUSP00000308946
resolver
ensp
ENSMUSP00000308954
resolver
ensp
ENSMUSP00000308955
resolver
ensp
ENSMUSP00000308956
resolver
ensp
ENSMUSP00000308957
resolver
ensp
ENSMUSP00000308958
resolver
ensp
ENSMUSP00000308959
resolver
ensp
ENSMUSP00000308963
resolver
ensp
ENSMUSP00000308967
resolver
ensp
ENSMUSP00000308973
resolver
ensp
ENSMUSP00000308978
resolver
ensp
ENSMUSP00000308988
resolver
ensp
ENSMUSP00000308990
resolver
ensp
ENSMUSP00000308997
resolver
ensp
ENSMUSP00000309002
resolver
ensp
ENSMUSP00000309008
resolver
enst
ENSMUST00000067107
resolver
enst
ENSMUST00000130011
resolver
enst
ENSMUST00000132139
resolver
enst
ENSMUST00000135336
resolver
enst
ENSMUST00000139869
resolver
enst
ENSMUST00000171337
resolver
genesymbol
Sorbs2
resolver
genesymbol_syn
Argbp2
resolver
genesymbol_syn
Kiaa0777
resolver
uniprot
A0A0R4J1W0
resolver
uniprot
A0A0S3CWK3
resolver
uniprot
A0A1L7NR37
resolver
uniprot
A0ACM8QIJ7
resolver
uniprot
B2RXQ9
resolver
uniprot
B7ZWM6
resolver
uniprot
B9EKP8
resolver
uniprot
D3Z080
resolver
uniprot
E9Q0B0
resolver
uniprot
F6Q979
resolver
uniprot
F6RSU0
resolver
uniprot
Q3USC6
resolver
uniprot
Q80TS1
resolver
uniprot
Q8BJL6
resolver
uniprot
Q8BJU3
resolver
uniprot
Q8BLW9
resolver
uniprot
Q8BX47
resolver
uniprot
Q8CHU0
resolver
uniprot_entry
A0A0R4J1W0_MOUSE
resolver
uniprot_entry
A0A0S3CWK3_MOUSE
resolver
uniprot_entry
A0A1L7NR37_MOUSE
resolver
uniprot_entry
A0ACM8QIJ7_MOUSE
resolver
uniprot_entry
B2RXQ9_MOUSE
resolver
uniprot_entry
B7ZWM6_MOUSE
resolver
uniprot_entry
B9EKP8_MOUSE
resolver
uniprot_entry
D3Z080_MOUSE
resolver
uniprot_entry
F6Q979_MOUSE
resolver
uniprot_entry
F6RSU0_MOUSE
resolver
uniprot_entry
SRBS2_MOUSE
resolver
uniprot_sec
E9Q0B0
resolver
uniprot_sec
Q3USC6
resolver
uniprot_sec
Q80TS1
resolver
uniprot_sec
Q8BJL6
resolver
uniprot_sec
Q8BJU3
resolver
uniprot_sec
Q8BLW9
resolver
uniprot_sec
Q8BX47
resolver
uniprot_sec
Q8CHU0
resolver
amino_acid_sequence
MNTDSGGCARKRAAMSVTLTSVKRVQSSPNLLAAGRESQSPDSAWRSYNDRNPETLNGDATYSSLAAKGFRSVRPNLQDKRSPTQSQITINGNSGGAVSPVSYYQRPFSPSAYSLPASLNSSIIMQHGRSLDSAETYSQHAQSLDGTMGSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPGLYNSPYSAQSHPAAKTQTYRPLSKSHSDNGTDAFKEVPSPVPPPHVPPRPRDQSSTLKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPVSIYQSSIDRSLERPSSSASMAGDFRKRRKSEPAVGPLRGLGDQSSSRTSPGRADLPGSSSTFTKSFISSSPSSPSRAQGGDDSKMCPPLCSYSGLNGTPSGELECCNAYRQHLDVPGDSQRAITFKNGWQMARQNAEIWSSTEETVSPKIKSRSCDDLLNDDCDSFPDPKTKSESMGSLLCEEDSKESCPMTWASPYIQEVCGNSRSRLKHRSAHNAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYEKEQQHRGLLHGWSQSSTEEVPRDVVPTRISEFEKLIQKSKSMPNLGDEMLSPITLEPPQNGLCPKRRFSIESLLEEETQVRHPSQGQRSCKSNTLVPIHIEVTSDEQPRTHMEFSDSDQDGVVSDHSDYVHVEGSSFCSESDFDHFSFTSSESFYGSSHHHHHHHHHHRHLISSCKGRCPASYTRFTTMLKHERAKHENMDRPRRQEMDPGLSKLAFLVSPVPFRRKKILTPQKQTEKAKCKASVVEALDSALKDICDQIKAEKRRGSLPDNSILHRLISELLPQIPERNSSLHALKRSPMHQPFHPLPPDGASHCPLYQNDCGRMPHSASFPDVDTTSNYHAQDYGSALSLQDHESPRSYSSTLTDLGRSASRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPVQPGEIGEAIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKRNAKGAEDYPDPPLPHSYSSDRIYTLSSNKPQRPGFSHENIQGGGEPFQALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL
uniprot
proteins
function
FUNCTION: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 (By similarity). May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:O94875}.
uniprot
proteins
mass_dalton
132349
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by CBL. {ECO:0000250}.
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1180
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Apical cell membrane {ECO:0000250|UniProtKB:O94875}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:O94875}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:O94875}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Found at the Z line sarcomeres, stress fibers, dense bodies and focal adhesion. In pancreatic acinar cells, localized preferentially to the apical membrane. Colocalized with vinculin and filamentous actin at focal adhesions and lamellipodia of pancreatic cells. {ECO:0000250, ECO:0000250|UniProtKB:O94875}.
uniprot
proteins