RTL10
entrez
79680
canonical
uniprot
Q7L3V2
canonical
ensembl
ENSG00000215012
resolver
ensp
ENSP00000330596
resolver
ensp
ENSP00000384924
resolver
ensp
ENSP00000386111
resolver
enst
ENST00000328554
resolver
enst
ENST00000405640
resolver
enst
ENST00000407472
resolver
genesymbol
RTL10
resolver
genesymbol_syn
BOP
resolver
genesymbol_syn
C22orf29
resolver
hgnc
HGNC:26112
resolver
uniprot
A8K5E7
resolver
uniprot
D3DX21
resolver
uniprot
Q6MZM8
resolver
uniprot
Q6N000
resolver
uniprot
Q9H7A0
resolver
uniprot_entry
BOP_HUMAN
resolver
uniprot_sec
A8K5E7
resolver
uniprot_sec
D3DX21
resolver
uniprot_sec
Q6MZM8
resolver
uniprot_sec
Q6N000
resolver
uniprot_sec
Q9H7A0
resolver
amino_acid_sequence
MPRGRCRQQGPRIPIWAAANYANAHPWQQMDKASPGVAYTPLVDPWIERPCCGDTVCVRTTMEQKSTASGTCGGKPAERGPLAGHMPSSRPHRVDFCWVPGSDPGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLPLPDDYELFCQDLKEVVQDPNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSPGF
uniprot
proteins
function
FUNCTION: Could induce apoptosis in a BH3 domain-dependent manner. The direct interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity. {ECO:0000269|PubMed:23055042}.
uniprot
proteins
mass_dalton
39299
uniprot
proteins
mutagenesis
MUTAGEN 118; /note="L->A: Reduces the pro-apoptotic activity and interaction with VDAC1."; /evidence="ECO:0000269|PubMed:23055042"; MUTAGEN 120; /note="Q->A: No effect on interaction with VDAC1."; /evidence="ECO:0000269|PubMed:23055042"; MUTAGEN 122; /note="G->A: No effect on interaction with VDAC1."; /evidence="ECO:0000269|PubMed:23055042"; MUTAGEN 123; /note="D->A: Reduces the pro-apoptotic activity, no effect on interaction with VDAC1."; /evidence="ECO:0000269|PubMed:23055042
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
23055042
uniprot
proteins
sequence_length
364
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:23055042}.
uniprot
proteins