Klhdc8b
entrez
78267
canonical
uniprot
Q9D2D9
canonical
ensembl
ENSMUSG00000032609
resolver
ensp
ENSMUSP00000035232
resolver
ensp
ENSMUSP00000141453
resolver
ensp
ENSMUSP00000142325
resolver
enst
ENSMUST00000035232
resolver
enst
ENSMUST00000193286
resolver
enst
ENSMUST00000193895
resolver
genesymbol
Klhdc8b
resolver
uniprot_entry
KLD8B_MOUSE
resolver
amino_acid_sequence
MAAGGGRAFAWQVFPPMPTCRVYGTVAHQDGHLLVLGGCGRAGLPLDTAETLDMGSHTWLALAPLPTARAGAAAVVLGKQVLVVGGVDEVQSPVAAVEAFLADEGRWERRATLPQAAMGVATVERDGMVYALGGMGPDTAPQAQVLVYEPRRDCWLSLPSMPTPCYGASTFLHGNKIYVLGGRQGKLPVTAFEAFDLETRTWTRHPSLPSRRAFAGCAMAEGSVFSLGGLQQPGPHNFYSRPHFVNTVEMFDLEHGSWTKLPRSLRMRDKRADFVVGSLGGNIVAIGGLGNQPCPLASVESFSLARRRWEVLPAMPTARCSCSSLQAGPRLFVIGGVAQGPSQAVEALCLRDGV
uniprot
proteins
function
FUNCTION: Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells. {ECO:0000250|UniProtKB:Q8IXV7}.
uniprot
proteins
mass_dalton
37592
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
354
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8IXV7}. Midbody {ECO:0000250|UniProtKB:Q8IXV7}. Note=In mitotic cells, concentrates in the midbody of the cytoplasmic bridge linking daughter cells as they are about to separate during cytokinesis. {ECO:0000250|UniProtKB:Q8IXV7}.
uniprot
proteins