GLS2
entrez
27165
canonical
uniprot
Q9UI32
canonical
ensembl
ENSG00000135423
resolver
ensp
ENSP00000310447
resolver
ensp
ENSP00000543409
resolver
genesymbol
GLS2
resolver
genesymbol_syn
GA
resolver
hgnc
HGNC:29570
resolver
uniprot
B7Z8Q9
resolver
uniprot
Q8IX91
resolver
uniprot
Q9NYY2
resolver
uniprot
Q9UI31
resolver
uniprot_entry
GLSL_HUMAN
resolver
uniprot_sec
B7Z8Q9
resolver
uniprot_sec
Q8IX91
resolver
uniprot_sec
Q9NYY2
resolver
uniprot_sec
Q9UI31
resolver
amino_acid_sequence
MRSMKALQKALSRAGSHCGRGGWGHPSRSPLLGGGVRHHLSEAAAQGRETPHSHQPQHQDHDSSESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSEMHRVVQESSSGGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDVKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGTSFCQKLVSLFNFHNYDNLRHCARKLDPRREGAEIRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTLSETQAEAAAEALSKENLESMV
uniprot
proteins
ec_number
3.5.1.2
uniprot
proteins
function
FUNCTION: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. {ECO:0000269|PubMed:20378837}.
uniprot
proteins
mass_dalton
66323
uniprot
proteins
protein_family
Glutaminase family
uniprot
proteins
pubmed
10620514
uniprot
proteins
pubmed
11163757
uniprot
proteins
pubmed
12444921
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
20378837
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28526749
uniprot
proteins
sequence_length
602
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:20378837}.
uniprot
proteins