Kcnc4
entrez
684516
canonical
uniprot
Q63734
canonical
ensembl
ENSRNOG00000060988
resolver
ensp
ENSRNOP00000068863
resolver
ensp
ENSRNOP00000087803
resolver
ensp
ENSRNOP00000100695
resolver
enst
ENSRNOT00000086420
resolver
enst
ENSRNOT00000093977
resolver
enst
ENSRNOT00000162236
resolver
genesymbol
Kcnc4
resolver
uniprot
A0A0G2JTV8
resolver
uniprot
A0A8I6GGE0
resolver
uniprot
A0ABK0LD18
resolver
uniprot_entry
A0A0G2JTV8_RAT
resolver
uniprot_entry
A0A8I6GGE0_RAT
resolver
uniprot_entry
A0ABK0LD18_RAT
resolver
uniprot_entry
KCNC4_RAT
resolver
amino_acid_sequence
MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGGGAGPGDEAGDDERELALQRLGPHEGGSGPGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNITSVRFRREVETEPILTYIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSEETSPRDSTYSDTSPPAREEGMVERKRADSKQNGDANAVLSDEEGAGLTQPLASAPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACADGSVQKEGSVEPKACVPVSHTCAL
uniprot
proteins
function
FUNCTION: Voltage-gated potassium channel that opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:12592408, PubMed:1378392, PubMed:1840526). The channel displays rapid activation and inactivation kinetics (PubMed:12592408, PubMed:1378392, PubMed:1840526). {ECO:0000269|PubMed:12592408, ECO:0000269|PubMed:1378392, ECO:0000269|PubMed:1840526}.
uniprot
proteins
mass_dalton
68435
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of serine residues in the inactivation gate inhibits rapid channel closure. {ECO:0000250|UniProtKB:Q03721}.
uniprot
proteins
protein_family
C (Shaw) (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv3.4/KCNC4 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
12592408
uniprot
proteins
pubmed
1378392
uniprot
proteins
pubmed
1840526
uniprot
proteins
sequence_length
625
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 228..248; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 279..299; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 346..365; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 382..402; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 453..473; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins