GTF2F1
entrez
2962
canonical
uniprot
P35269
canonical
ensembl
ENSG00000125651
resolver
ensp
ENSP00000377969
resolver
ensp
ENSP00000469091
resolver
enst
ENST00000394456
resolver
genesymbol
GTF2F1
resolver
genesymbol_syn
RAP74
resolver
hgnc
HGNC:4652
resolver
uniprot
B2RCS0
resolver
uniprot
Q9BWN0
resolver
uniprot_entry
T2FA_HUMAN
resolver
uniprot_sec
B2RCS0
resolver
uniprot_sec
Q9BWN0
resolver
amino_acid_sequence
MAALGPSSQNVTEYVVRVPKNTTKKYNIMAFNAADKVNFATWNQARLERDLSNKKIYQEEEMPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLKE
uniprot
proteins
function
FUNCTION: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. {ECO:0000269|PubMed:10428810}.
uniprot
proteins
mass_dalton
58240
uniprot
proteins
mutagenesis
MUTAGEN 385; /note="S->A: Eliminates putative kinase activity; when associated with A-389."; /evidence="ECO:0000269|PubMed:10428810"; MUTAGEN 389; /note="T->A: Eliminates putative kinase activity; when associated with A-385."; /evidence="ECO:0000269|PubMed:10428810
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases. {ECO:0000269|PubMed:10428810, ECO:0000269|PubMed:8625415}.
uniprot
proteins
protein_family
TFIIF alpha subunit family
uniprot
proteins
pubmed
10428810
uniprot
proteins
pubmed
11183778
uniprot
proteins
pubmed
11248041
uniprot
proteins
pubmed
12578358
uniprot
proteins
pubmed
12591941
uniprot
proteins
pubmed
12732728
uniprot
proteins
pubmed
12737519
uniprot
proteins
pubmed
12931194
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16548883
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
1734283
uniprot
proteins
pubmed
1734284
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
27193682
uniprot
proteins
pubmed
7667268
uniprot
proteins
pubmed
8625415
uniprot
proteins
pubmed
8662660
uniprot
proteins
sequence_length
517
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins