Lancl2
entrez
71835
canonical
uniprot
Q9JJK2
canonical
ensembl
ENSMUSG00000062190
resolver
ensp
ENSMUSP00000052146
resolver
ensp
ENSMUSP00000072723
resolver
enst
ENSMUST00000050077
resolver
enst
ENSMUST00000072954
resolver
genesymbol
Lancl2
resolver
genesymbol_syn
Tasp
resolver
uniprot_entry
LANC2_MOUSE
resolver
amino_acid_sequence
MGETMSKRLKFHLGEAEMEERSFPNPFPDYEAAASAAGLAAGSAEETGRVCPLPTTEDPGLPFHPNGKIVPNFIKRIQTKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVTGDQTYLLRSLDYVKRTLRNLSGRRVTFLCGDAGPLAVGAVIYHKLKSECESQECITKLLQMHRTIVCQESELPDELLYGRAGYLYALLYLNTEIGPGTVGETAIKEVVSAIIESGKSLSREERKSERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPEAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGVIHVLLQAYQVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTSGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEGMAGAVHFLSDILVPETARFPAFELGFLQKD
uniprot
proteins
function
FUNCTION: Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. {ECO:0000250|UniProtKB:Q9NS86}.
uniprot
proteins
mass_dalton
50777
uniprot
proteins
post_translational_modification
PTM: Myristoylated. Essential for membrane association. {ECO:0000250|UniProtKB:Q9NS86}.
uniprot
proteins
protein_family
LanC-like protein family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
450
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NS86}. Cytoplasm {ECO:0000250|UniProtKB:Q9NS86}. Cell membrane {ECO:0000250|UniProtKB:Q9NS86}. Note=Localizes to the juxta-nuclear vesicles. Associates with the cortical actin cytoskeleton. Cholesterol depletion by methyl-beta-cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo. {ECO:0000250|UniProtKB:Q9NS86}.
uniprot
proteins