DNASE1L2
entrez
1775
canonical
uniprot
Q92874
canonical
ensembl
ENSG00000167968
resolver
ensp
ENSP00000316938
resolver
ensp
ENSP00000454562
resolver
ensp
ENSP00000455358
resolver
genesymbol
DNASE1L2
resolver
genesymbol_syn
DHP1
resolver
genesymbol_syn
DNAS1L2
resolver
hgnc
HGNC:2958
resolver
uniprot
E9PBY4
resolver
uniprot
Q6JVM2
resolver
uniprot
Q6JVM3
resolver
uniprot_entry
DNSL2_HUMAN
resolver
uniprot_sec
E9PBY4
resolver
uniprot_sec
Q6JVM2
resolver
uniprot_sec
Q6JVM3
resolver
amino_acid_sequence
MGGPRALLAALWALEAAGTAALRIGAFNIQSFGDSKVSDPACGSIIAKILAGYDLALVQEVRDPDLSAVSALMEQINSVSEHEYSFVSSQPLGRDQYKEMYLFVYRKDAVSVVDTYLYPDPEDVFSREPFVVKFSAPGTGERAPPLPSRRALTPPPLPAAAQNLVLIPLHAAPHQAVAEIDALYDVYLDVIDKWGTDDMLFLGDFNADCSYVRAQDWAAIRLRSSEVFKWLIPDSADTTVGNSDCAYDRIVACGARLRRSLKPQSATVHDFQEEFGLDQTQALAISDHFPVEVTLKFHR
uniprot
proteins
ec_number
3.1.21.-
uniprot
proteins
function
FUNCTION: Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells. {ECO:0000269|PubMed:16902420}.
uniprot
proteins
mass_dalton
32853
uniprot
proteins
protein_family
DNase I family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15203207
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
16902420
uniprot
proteins
pubmed
9205125
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16902420}. Secreted {ECO:0000305}.
uniprot
proteins