Flt3l
entrez
14256
canonical
uniprot
P49772
canonical
ensembl
ENSMUSG00000110206
resolver
ensp
ENSMUSP00000123506
resolver
ensp
ENSMUSP00000147468
resolver
ensp
ENSMUSP00000148009
resolver
ensp
ENSMUSP00000172039
resolver
genesymbol
Flt3l
resolver
genesymbol
Flt3lg
resolver
genesymbol_syn
Flt3l
resolver
uniprot
A9QW46
resolver
uniprot
Q64085
resolver
uniprot_entry
A9QW46_MOUSE
resolver
uniprot_entry
FLT3L_MOUSE
resolver
uniprot_sec
Q64085
resolver
amino_acid_sequence
MTVLAPAWSPNSSLLLLLLLLSPCLRGTPDCYFSHSPISSNFKVKFRELTDHLLKDYPVTVAVNLQDEKHCKALWSLFLAQRWIEQLKTVAGSKMQTLLEDVNTEIHFVTSCTFQPLPECLRFVQTNISHLLKDTCTQLLALKPCIGKACQNFSRCLEVQCQPDSSTLLPPRSPIALEATELPEPRPRQLLLLLLLLLPLTLVLLAAAWGLRWQRARRRGELHPGVPLPSHP
uniprot
proteins
function
FUNCTION: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. Essential for the development of natural killer (NK) cells, B cells, and dendritic cells (DCs). {ECO:0000269|PubMed:38701783}.
uniprot
proteins
mass_dalton
26141
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
38701783
uniprot
proteins
pubmed
7505204
uniprot
proteins
pubmed
7566977
uniprot
proteins
pubmed
7824267
uniprot
proteins
pubmed
8145851
uniprot
proteins
sequence_length
232
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted. Note=Biologically active.; SUBCELLULAR LOCATION: [Isoform 4]: Secreted. Note=Inactive.
uniprot
proteins
transmembrane_region
TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins