GLIS1
entrez
148979
canonical
uniprot
Q8NBF1
canonical
ensembl
ENSG00000174332
resolver
ensp
ENSP00000309653
resolver
ensp
ENSP00000486112
resolver
ensp
ENSP00000534044
resolver
ensp
ENSP00000624931
resolver
enst
ENST00000312233
resolver
enst
ENST00000628545
resolver
genesymbol
GLIS1
resolver
hgnc
HGNC:29525
resolver
uniprot
A0A0D9SEX9
resolver
uniprot
Q2M3G9
resolver
uniprot
Q8N9V9
resolver
uniprot_entry
A0A0D9SEX9_HUMAN
resolver
uniprot_entry
GLIS1_HUMAN
resolver
uniprot_sec
Q2M3G9
resolver
uniprot_sec
Q8N9V9
resolver
amino_acid_sequence
MAEARTSLSAHCRGPLATGLHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSSPCASSDVTSIIRSSQTSLVTCVNGLRSPPLTGDLGGPSKRARPGPASTDSHEGSLQLEACRKASFLKQEPADEFSELFGPHQQGLPPPYPLSQLPPGPSLGGLGLGLAGRVVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTEADVLTECLVLQQLHTSTQLAASDGKGGCGLGQELLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLSPLPMAESTRDGLGPGLLSPIVSPLKGLGPPPLPPSSQSHSPGGQPFPTLPSKPSYPPFQSPPPPPLPSPQGYQGSFHSIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCPTALPQQPSEDVVSSGPEDCGFFPNGAFDHCLGHIPSIYTDT
uniprot
proteins
function
FUNCTION: Acts both as a repressor and an activator of transcription (PubMed:21654807). Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity). By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells (PubMed:21654807). Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast (By similarity). {ECO:0000250|UniProtKB:Q8K1M4, ECO:0000269|PubMed:21654807}.
uniprot
proteins
mass_dalton
65976
uniprot
proteins
protein_family
GLI C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21654807
uniprot
proteins
pubmed
28750082
uniprot
proteins
sequence_length
620
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8K1M4}.
uniprot
proteins