EGFLAM
entrez
133584
canonical
uniprot
Q63HQ2
canonical
ensembl
ENSG00000164318
resolver
ensp
ENSP00000313084
resolver
ensp
ENSP00000337607
resolver
ensp
ENSP00000346964
resolver
ensp
ENSP00000380393
resolver
genesymbol
EGFLAM
resolver
genesymbol_syn
AGRINL
resolver
genesymbol_syn
AGRNL
resolver
genesymbol_syn
PIKA
resolver
hgnc
HGNC:26810
resolver
uniprot
A8K6D7
resolver
uniprot
Q5U643
resolver
uniprot
Q6P3V1
resolver
uniprot
Q8N124
resolver
uniprot
Q8N197
resolver
uniprot
Q8N7Y0
resolver
uniprot
Q8N8N5
resolver
uniprot
Q8NAL2
resolver
uniprot_entry
EGFLA_HUMAN
resolver
uniprot_sec
A8K6D7
resolver
uniprot_sec
Q5U643
resolver
uniprot_sec
Q6P3V1
resolver
uniprot_sec
Q8N124
resolver
uniprot_sec
Q8N197
resolver
uniprot_sec
Q8N7Y0
resolver
uniprot_sec
Q8N8N5
resolver
uniprot_sec
Q8NAL2
resolver
amino_acid_sequence
MDLIRGVLLRLLLLASSLGPGAVSLRAAIRKPGKVGPPLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTTEEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSEVALSWKPGASEGSAPIQYYSVEFIRPDFDKKWTSIHERIQMDSMVIKGLDPDTNYQFAVRAMNSHGPSPRSWPSDIIRTLCPEEAGSGRYGPRYITDMGAGEDDEGFEDDLDLDISFEEVKPLPATKGGNKKFLVESKKMSISNPKTISRLIPPTSASLPVTTVAPQPIPIQRKGKNGVAIMSRLFDMPCDETLCSADSFCVNDYTWGGSRCQCTLGKGGESCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKECGNYCLNTIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMRGLVGCISHFTLSTDYHISLVEDAVDGKNINTCGAK
uniprot
proteins
function
FUNCTION: Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. {ECO:0000250|UniProtKB:Q4VBE4}.
uniprot
proteins
mass_dalton
111271
uniprot
proteins
post_translational_modification
PTM: O-glycosylated; contains chondroitin sulfate and heparan sulfate. {ECO:0000250|UniProtKB:Q4VBE4}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
1017
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q4VBE4}. Synaptic cleft {ECO:0000250|UniProtKB:Q4VBE4}. Presynaptic active zone {ECO:0000250|UniProtKB:Q4VBE4}. Note=Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals. {ECO:0000250|UniProtKB:Q4VBE4}.
uniprot
proteins