N4bp3
entrez
212706
canonical
uniprot
Q8C7U1
canonical
ensembl
ENSMUSG00000001053
resolver
ensp
ENSMUSP00000001080
resolver
ensp
ENSMUSP00000192058
resolver
ensp
ENSMUSP00000192064
resolver
ensp
ENSMUSP00000339023
resolver
enst
ENSMUST00000001080
resolver
genesymbol
N4bp3
resolver
uniprot
A2AA64
resolver
uniprot
Q3TDC7
resolver
uniprot
Q3URT6
resolver
uniprot
Q7TNR2
resolver
uniprot
Q922W0
resolver
uniprot
Q99J06
resolver
uniprot_entry
N4BP3_MOUSE
resolver
uniprot_sec
A2AA64
resolver
uniprot_sec
Q3TDC7
resolver
uniprot_sec
Q3URT6
resolver
uniprot_sec
Q7TNR2
resolver
uniprot_sec
Q922W0
resolver
uniprot_sec
Q99J06
resolver
amino_acid_sequence
MATTSGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGKTTKRAPRNEPDYATLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVGSGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRAPRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEVAVLPEAREELKRDLGDQDVSNSFTQVLEERQRLWLSELKRLYVERLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGSSMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVHSLQEQAPREEAPGSCETDDCKSRGLLGEAGGSEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEHELRLLREPPTSWSPRLESSKI
uniprot
proteins
function
FUNCTION: Plays a positive role in the antiviral innate immune signaling pathway. Mechanistically, interacts with MAVS and functions as a positive regulator to promote 'Lys-63'-linked polyubiquitination of MAVS and thus strengthens the interaction between MAVS and TRAF2 (By similarity). Also plays a role in axon and dendrite arborization during cranial nerve development. May also be important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage (By similarity). {ECO:0000250|UniProtKB:A0A1L8GXY6, ECO:0000250|UniProtKB:O15049}.
uniprot
proteins
mass_dalton
60042
uniprot
proteins
protein_family
N4BP3 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
537
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q3LUD3}. Cell projection, axon {ECO:0000250|UniProtKB:Q3LUD3}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q3LUD3}. Note=In developing neurons, accumulates in early growth cones and at branching points of axons and dendrites. {ECO:0000250|UniProtKB:Q3LUD3}.
uniprot
proteins