Apoa1
entrez
25081
canonical
uniprot
P04639
canonical
ensembl
ENSRNOG00000045679
resolver
ensembl
ENSRNOG00055019759
resolver
ensembl
ENSRNOG00060014072
resolver
ensembl
ENSRNOG00065027868
resolver
ensp
ENSRNOP00000065206
resolver
ensp
ENSRNOP00055027394
resolver
ensp
ENSRNOP00060019203
resolver
ensp
ENSRNOP00065039487
resolver
enst
ENSRNOT00000074357
resolver
enst
ENSRNOT00055033746
resolver
enst
ENSRNOT00060024085
resolver
enst
ENSRNOT00065048097
resolver
genesymbol
Apoa1
resolver
uniprot
O08877
resolver
uniprot
O09054
resolver
uniprot
Q5EBB2
resolver
uniprot_entry
APOA1_RAT
resolver
uniprot_sec
O08877
resolver
uniprot_sec
O09054
resolver
uniprot_sec
Q5EBB2
resolver
amino_acid_sequence
MKAAVLAVALVFLTGCQAWEFWQQDEPQSQWDRVKDFATVYVDAVKDSGRDYVSQFESSTLGKQLNLNLLDNWDTLGSTVGRLQEQLGPVTQEFWANLEKETDWLRNEMNKDLENVKQKMQPHLDEFQEKWNEEVEAYRQKLEPLGTELHKNAKEMQRHLKVVAEEFRDRMRVNADALRAKFGLYSDQMRENLAQRLTEIKNHPTLIEYHTKASDHLKTLGEKAKPALDDLGQGLMPVLEAWKAKIMSMIDEAKKKLNA
uniprot
proteins
function
FUNCTION: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
uniprot
proteins
mass_dalton
30062
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250}.; PTM: Palmitoylated. {ECO:0000250}.; PTM: Phosphorylation sites are present in the extracellular medium. {ECO:0000250}.; PTM: Some tyrosine residues are chlorinated and nitrated: chlorination and nitration takes place when the lipid-free form of APOA1 is exposed to hypochlorous acid and peroxynitrite oxidants, respectively, which are generated by myeloperoxidase (MPO). {ECO:0000250|UniProtKB:P02647}.
uniprot
proteins
protein_family
Apolipoprotein A1/A4/E family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
3020028
uniprot
proteins
pubmed
6426956
uniprot
proteins
pubmed
6798036
uniprot
proteins
pubmed
9415807
uniprot
proteins
sequence_length
259
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins