Lgals1
entrez
56646
canonical
uniprot
P11762
canonical
ensembl
ENSRNOG00000009884
resolver
ensembl
ENSRNOG00055029042
resolver
ensembl
ENSRNOG00060022902
resolver
ensembl
ENSRNOG00065032053
resolver
ensp
ENSRNOP00000013538
resolver
ensp
ENSRNOP00055041419
resolver
ensp
ENSRNOP00060032908
resolver
ensp
ENSRNOP00065045401
resolver
enst
ENSRNOT00000013538
resolver
enst
ENSRNOT00055050333
resolver
enst
ENSRNOT00060039818
resolver
enst
ENSRNOT00065055210
resolver
genesymbol
Lgals1
resolver
uniprot_entry
LEG1_RAT
resolver
amino_acid_sequence
MACGLVASNLNLKPGECLKVRGELAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWGTEQRETAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE
uniprot
proteins
function
FUNCTION: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69. {ECO:0000250|UniProtKB:P09382}.
uniprot
proteins
mass_dalton
14857
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2319298
uniprot
proteins
pubmed
3349058
uniprot
proteins
sequence_length
135
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P09382}. Cytoplasm {ECO:0000250|UniProtKB:P09382}. Secreted {ECO:0000250|UniProtKB:P09382}. Note=Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. {ECO:0000250|UniProtKB:P09382}.
uniprot
proteins