OGFOD1
entrez
55239
canonical
uniprot
Q8N543
canonical
ensembl
ENSG00000087263
resolver
ensp
ENSP00000457258
resolver
ensp
ENSP00000547408
resolver
ensp
ENSP00000547409
resolver
genesymbol
OGFOD1
resolver
genesymbol_syn
KIAA1612
resolver
genesymbol_syn
TPA1
resolver
hgnc
HGNC:25585
resolver
uniprot
H3BUQ2
resolver
uniprot
Q9H7U5
resolver
uniprot
Q9H9J9
resolver
uniprot
Q9HA87
resolver
uniprot
Q9HCG0
resolver
uniprot
Q9NVB6
resolver
uniprot_entry
OGFD1_HUMAN
resolver
uniprot_sec
H3BUQ2
resolver
uniprot_sec
Q9H7U5
resolver
uniprot_sec
Q9H9J9
resolver
uniprot_sec
Q9HA87
resolver
uniprot_sec
Q9HCG0
resolver
uniprot_sec
Q9NVB6
resolver
amino_acid_sequence
MNGKRPAEPGPARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDPFLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISTLRKILFEDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSMGGTLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNYFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHGHVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAETTDITEEGTSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE
uniprot
proteins
ec_number
1.14.11.-
uniprot
proteins
function
FUNCTION: Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation. {ECO:0000269|PubMed:20154146, ECO:0000269|PubMed:24550447, ECO:0000269|PubMed:24550462}.
uniprot
proteins
mass_dalton
63246
uniprot
proteins
mutagenesis
MUTAGEN 155; /note="H->A: Loss of function."; /evidence="ECO:0000269|PubMed:20579638"; MUTAGEN 157; /note="D->A: Loss of function."; /evidence="ECO:0000269|PubMed:24550447
uniprot
proteins
protein_family
TPA1 family
uniprot
proteins
pubmed
10997877
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
20154146
uniprot
proteins
pubmed
20579638
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22002106
uniprot
proteins
pubmed
24550447
uniprot
proteins
pubmed
24550462
uniprot
proteins
pubmed
25728928
uniprot
proteins
sequence_length
542
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Nucleus. Note=Mainly nuclear. A portion relocalizes to cytoplasmic stress granules upon stress.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
uniprot
proteins