PRDM10
entrez
56980
canonical
uniprot
Q9NQV6
canonical
ensembl
ENSG00000170325
resolver
ensp
ENSP00000302669
resolver
ensp
ENSP00000351686
resolver
ensp
ENSP00000354118
resolver
ensp
ENSP00000398431
resolver
ensp
ENSP00000432237
resolver
ensp
ENSP00000557411
resolver
ensp
ENSP00000605576
resolver
genesymbol
PRDM10
resolver
genesymbol_syn
KIAA1231
resolver
genesymbol_syn
PFM7
resolver
genesymbol_syn
TRIS
resolver
hgnc
HGNC:13995
resolver
uniprot
B7ZL71
resolver
uniprot
G3XAE5
resolver
uniprot
J3KP23
resolver
uniprot
Q17R90
resolver
uniprot
Q2KHR4
resolver
uniprot
Q863Z2
resolver
uniprot
Q9NXI4
resolver
uniprot
Q9ULI9
resolver
uniprot_entry
PRD10_HUMAN
resolver
uniprot_sec
B7ZL71
resolver
uniprot_sec
G3XAE5
resolver
uniprot_sec
J3KP23
resolver
uniprot_sec
Q17R90
resolver
uniprot_sec
Q2KHR4
resolver
uniprot_sec
Q863Z2
resolver
uniprot_sec
Q9NXI4
resolver
uniprot_sec
Q9ULI9
resolver
amino_acid_sequence
MDSKDESSHVWPTSAEHEQNAAQVHFVPDTGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPGQVAYVQQDATAQQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRLELQNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVASATSPHQSQQSTVDVGQLHDPQPYPQHAIQVQHIQVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP
uniprot
proteins
disease_involvement
DISEASE: Birt-Hogg-Dube syndrome 2 (BHD2) [MIM:620459]: A form of Birt-Hogg-Dube syndrome, a rare genodermatosis usually manifesting in adulthood and characterized by multiple fibrofolliculomas, trichodiscomas, and acrochordons. Patients with this syndrome have an increased susceptibility to develop renal cell carcinoma, lung cysts, and spontaneous pneumothorax. BHD2 inheritance is autosomal dominant. {ECO:0000269|PubMed:36440963}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Transcriptional activator, essential for early embryonic development and survival of embryonic stem cells (ESCs) (By similarity). Supports cell growth and survival during early development by transcriptionally activating the expression of the translation initiation factor EIF3B, to sustain global translation (By similarity). Activates the transcription of FLNC (PubMed:36440963). {ECO:0000250|UniProtKB:Q3UTQ7, ECO:0000269|PubMed:36440963}.
uniprot
proteins
mass_dalton
130136
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
pubmed
10574462
uniprot
proteins
pubmed
10668202
uniprot
proteins
pubmed
12175877
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
36440963
uniprot
proteins
sequence_length
1147
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:36440963}.
uniprot
proteins