Cct5
entrez
294864
canonical
uniprot
Q68FQ0
canonical
ensembl
ENSRNOG00000011632
resolver
ensp
ENSRNOP00000015886
resolver
genesymbol
Cct5
resolver
uniprot
Q6PCT4
resolver
uniprot_entry
TCPE_RAT
resolver
uniprot_sec
Q6PCT4
resolver
amino_acid_sequence
MASVGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQHLDKISDNVLVDINNPEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKEVLNAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIAQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWVGGPEIELIAIATGGRIVPRFSELTSEKLGFAGVVREISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKESNPALGIDCLHKGSNDMQYQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE
uniprot
proteins
ec_number
3.6.1.-
uniprot
proteins
function
FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. {ECO:0000250|UniProtKB:P48643}.
uniprot
proteins
mass_dalton
59537
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the DCX(DCAF12) complex specifically recognizes the diglutamate (Glu-Glu) at the C-terminus, leading to its degradation. {ECO:0000250|UniProtKB:P48643}.
uniprot
proteins
protein_family
TCP-1 chaperonin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
541
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P48643}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:P48643}.
uniprot
proteins