Copz1
entrez
56447
canonical
uniprot
P61924
canonical
ensembl
ENSMUSG00000060992
resolver
ensp
ENSMUSP00000097738
resolver
ensp
ENSMUSP00000306638
resolver
enst
ENSMUST00000100162
resolver
genesymbol
Copz1
resolver
genesymbol_syn
Copz
resolver
uniprot
Q542M2
resolver
uniprot
Q9Y3C3
resolver
uniprot_entry
COPZ1_MOUSE
resolver
uniprot_entry
Q542M2_MOUSE
resolver
uniprot_sec
Q9Y3C3
resolver
amino_acid_sequence
MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
uniprot
proteins
function
FUNCTION: Component of the coatomer complex, involved in retrograde Golgi-to-ER transport (By similarity). The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity). {ECO:0000250|UniProtKB:P53600, ECO:0000250|UniProtKB:P61923}.
uniprot
proteins
mass_dalton
20198
uniprot
proteins
protein_family
Adaptor complexes small subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
177
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}.
uniprot
proteins