CCDC69
entrez
26112
canonical
uniprot
A6NI79
canonical
ensembl
ENSG00000198624
resolver
ensp
ENSP00000347586
resolver
enst
ENST00000355417
resolver
genesymbol
CCDC69
resolver
hgnc
HGNC:24487
resolver
uniprot
A8K9X6
resolver
uniprot
Q7L2X4
resolver
uniprot_entry
CCD69_HUMAN
resolver
uniprot_entry
Q7L2X4_HUMAN
resolver
uniprot_sec
A8K9X6
resolver
amino_acid_sequence
MGCRHSRLSSCKPPKKKRQEPEPEQPPRPEPHELGPLNGDTAITVQLCASEEAERHQKDITRILQQHEEEKKKWAQQVEKERELELRDRLDEQQRVLEGKNEEALQVLRASYEQEKEALTHSFREASSTQQETIDRLTSQLEAFQAKMKRVEESILSRNYKKHIQDYGSPSQFWEQELESLHFVIEMKNERIHELDRRLILMETVKEKNLILEEKITTLQQENEDLHVRSRNQVVLSRQLSEDLLLTREALEKEVQLRRQLQQEKEELLYRVLGANASPAFPLAPVTPTEVSFLAT
uniprot
proteins
function
FUNCTION: May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone. {ECO:0000305|PubMed:20962590}.
uniprot
proteins
mass_dalton
34796
uniprot
proteins
protein_family
CCDC69 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
20962590
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
296
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:20962590}. Midbody {ECO:0000269|PubMed:20962590}. Note=During early anaphase, localizes along overlapping interpolar microtubules between the separating chromosomes. During late anaphase, localizes to the center of spindle midzone. Concentrated at the midbody during telophase. {ECO:0000269|PubMed:20962590}.
uniprot
proteins