Kcnip2
entrez
56817
canonical
uniprot
Q9JM59
canonical
ensembl
ENSRNOG00000018018
resolver
ensembl
ENSRNOG00055004441
resolver
ensembl
ENSRNOG00060023989
resolver
ensembl
ENSRNOG00065029650
resolver
ensp
ENSRNOP00000024709
resolver
ensp
ENSRNOP00000024750
resolver
ensp
ENSRNOP00000050779
resolver
ensp
ENSRNOP00000111656
resolver
enst
ENSRNOT00000048592
resolver
genesymbol
Kcnip2
resolver
genesymbol_syn
Kchip2
resolver
uniprot
A0A140TAG7
resolver
uniprot
D5LL09
resolver
uniprot
Q9JI21
resolver
uniprot
Q9JI22
resolver
uniprot
Q9JI23
resolver
uniprot
Q9JM60
resolver
uniprot_entry
A0A140TAG7_RAT
resolver
uniprot_entry
D5LL09_RAT
resolver
uniprot_entry
KCIP2_RAT
resolver
uniprot_sec
Q9JI21
resolver
uniprot_sec
Q9JI22
resolver
uniprot_sec
Q9JI23
resolver
uniprot_sec
Q9JM60
resolver
amino_acid_sequence
MRGQGRKESLSESRDLDGSYDQLTGHPPGPSKKALKQRFLKLLPCCGPQALPSVSETLAAPASLRPHRPRPLDPDSVEDEFELSTVCHRPEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSNYATFLFNAFDTNHDGSVSFEDFVAGLSVILRGTIDDRLSWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMRSMQLFDNVI
uniprot
proteins
function
FUNCTION: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels (PubMed:10676964, PubMed:16820361). Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:10676964, PubMed:16820361). Involved in KCND2 and KCND3 trafficking to the cell surface (By similarity). Essential for the expression of I(To) currents in the heart (By similarity). Required for normal protein levels of KCND2 in the heart ventricle (By similarity). {ECO:0000250|UniProtKB:Q9JJ69, ECO:0000250|UniProtKB:Q9NS61, ECO:0000269|PubMed:10676964, ECO:0000269|PubMed:16820361}.
uniprot
proteins
mass_dalton
30933
uniprot
proteins
mutagenesis
MUTAGEN 45..46; /note="CC->AA,SS: Abolishes plasma membrane localization."; /evidence="ECO:0000269|PubMed:12006572
uniprot
proteins
post_translational_modification
PTM: Palmitoylated. Palmitoylation enhances association with the plasma membrane. {ECO:0000269|PubMed:12006572}.
uniprot
proteins
protein_family
Recoverin family
uniprot
proteins
pubmed
10676964
uniprot
proteins
pubmed
11263977
uniprot
proteins
pubmed
12006572
uniprot
proteins
pubmed
12646414
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16820361
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
24793047
uniprot
proteins
sequence_length
270
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11263977, ECO:0000269|PubMed:12006572, ECO:0000269|PubMed:16820361, ECO:0000269|PubMed:24793047}; Lipid-anchor {ECO:0000269|PubMed:12006572}. Note=Detected on lipid rafts. {ECO:0000269|PubMed:24793047}.
uniprot
proteins