PRAF2
entrez
11230
canonical
uniprot
O60831
canonical
ensembl
ENSG00000243279
resolver
ensembl
ENSG00000292222
resolver
ensp
ENSP00000451962
resolver
ensp
ENSP00000518158
resolver
enst
ENST00000553851
resolver
enst
ENST00000710261
resolver
genesymbol
PRAF2
resolver
hgnc
HGNC:28911
resolver
uniprot
B2RD20
resolver
uniprot_entry
PRAF2_HUMAN
resolver
uniprot_sec
B2RD20
resolver
amino_acid_sequence
MSEVRLPPLRALDDFVLGSARLAAPDPCDPQRWCHRVINNLLYYQTNYLLCFGIGLALAGYVRPLHTLLSALVVAVALGVLVWAAETRAAVRRCRRSHPAACLAAVLAVGLLVLWVAGGACTFLFSIAGPVLLILVHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS
uniprot
proteins
function
FUNCTION: May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis. {ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}.
uniprot
proteins
mass_dalton
19258
uniprot
proteins
protein_family
PRA1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15757671
uniprot
proteins
pubmed
16472945
uniprot
proteins
pubmed
16481131
uniprot
proteins
pubmed
17975142
uniprot
proteins
pubmed
18395978
uniprot
proteins
pubmed
21269460
uniprot
proteins
sequence_length
178
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane {ECO:0000305|PubMed:17975142}; Multi-pass membrane protein {ECO:0000305|PubMed:17975142}.
uniprot
proteins
transmembrane_region
TRANSMEM 42..62; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 65..85; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 97..119; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 123..140; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins