TPST1
entrez
8460
canonical
uniprot
O60507
canonical
ensembl
ENSG00000169902
resolver
ensp
ENSP00000302413
resolver
ensp
ENSP00000497281
resolver
ensp
ENSP00000574495
resolver
ensp
ENSP00000574496
resolver
ensp
ENSP00000574497
resolver
ensp
ENSP00000574498
resolver
ensp
ENSP00000574499
resolver
ensp
ENSP00000574500
resolver
ensp
ENSP00000574501
resolver
ensp
ENSP00000574502
resolver
ensp
ENSP00000574503
resolver
ensp
ENSP00000574504
resolver
ensp
ENSP00000574505
resolver
ensp
ENSP00000574506
resolver
ensp
ENSP00000574507
resolver
ensp
ENSP00000574508
resolver
ensp
ENSP00000605340
resolver
ensp
ENSP00000605341
resolver
ensp
ENSP00000605343
resolver
ensp
ENSP00000605344
resolver
ensp
ENSP00000637717
resolver
ensp
ENSP00000637718
resolver
ensp
ENSP00000637719
resolver
ensp
ENSP00000637720
resolver
ensp
ENSP00000637721
resolver
ensp
ENSP00000780612
resolver
enst
ENST00000304842
resolver
enst
ENST00000649664
resolver
enst
ENST00000904436
resolver
enst
ENST00000904437
resolver
enst
ENST00000904438
resolver
enst
ENST00000904439
resolver
enst
ENST00000904441
resolver
enst
ENST00000904442
resolver
enst
ENST00000904443
resolver
enst
ENST00000904445
resolver
enst
ENST00000904446
resolver
enst
ENST00000904447
resolver
enst
ENST00000904448
resolver
enst
ENST00000904449
resolver
enst
ENST00000935281
resolver
enst
ENST00000935284
resolver
enst
ENST00000935285
resolver
enst
ENST00000967658
resolver
enst
ENST00000967659
resolver
enst
ENST00000967660
resolver
enst
ENST00000967661
resolver
enst
ENST00000967662
resolver
genesymbol
TPST1
resolver
hgnc
HGNC:12020
resolver
uniprot
A4D2M0
resolver
uniprot
Q6FGM7
resolver
uniprot_entry
TPST1_HUMAN
resolver
uniprot_sec
A4D2M0
resolver
uniprot_sec
Q6FGM7
resolver
amino_acid_sequence
MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQLPDFLKEKPQTEQVE
uniprot
proteins
ec_number
2.8.2.20
uniprot
proteins
function
FUNCTION: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate. {ECO:0000269|PubMed:28821720, ECO:0000269|PubMed:9501187, ECO:0000269|PubMed:9733778}.
uniprot
proteins
mass_dalton
42188
uniprot
proteins
mutagenesis
MUTAGEN 60; /note="N->A: Loss of one glycosylation site. Loss of N-glycosylation; when associated with A-262."; /evidence="ECO:0000269|PubMed:16859706"; MUTAGEN 262; /note="N->A: Loss of one glycosylation site. Loss of N-glycosylation; when associated with A-60."; /evidence="ECO:0000269|PubMed:16859706
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:16859706, ECO:0000269|PubMed:9501187}.
uniprot
proteins
protein_family
Protein sulfotransferase family
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16859706
uniprot
proteins
pubmed
25660941
uniprot
proteins
pubmed
28821720
uniprot
proteins
pubmed
9501187
uniprot
proteins
pubmed
9733778
uniprot
proteins
sequence_length
370
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:16859706, ECO:0000269|PubMed:25660941}; Single-pass type II membrane protein {ECO:0000269|PubMed:25660941, ECO:0000305|PubMed:16859706}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..25; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins