KIF3A
entrez
11127
canonical
uniprot
Q9Y496
canonical
ensembl
ENSG00000131437
resolver
ensp
ENSP00000368009
resolver
ensp
ENSP00000368020
resolver
ensp
ENSP00000385808
resolver
ensp
ENSP00000782080
resolver
ensp
ENSP00000782081
resolver
enst
ENST00000378735
resolver
enst
ENST00000378746
resolver
enst
ENST00000403231
resolver
genesymbol
KIF3A
resolver
genesymbol_syn
KIF3
resolver
hgnc
HGNC:6319
resolver
uniprot
A8MSW9
resolver
uniprot
B4DHG8
resolver
uniprot
E9PES4
resolver
uniprot
J3KPF9
resolver
uniprot
Q05CT3
resolver
uniprot
Q59EN1
resolver
uniprot
Q86XE9
resolver
uniprot
Q9Y6V4
resolver
uniprot_entry
B4DHG8_HUMAN
resolver
uniprot_entry
E9PES4_HUMAN
resolver
uniprot_entry
J3KPF9_HUMAN
resolver
uniprot_entry
KIF3A_HUMAN
resolver
uniprot_entry
Q05CT3_HUMAN
resolver
uniprot_sec
A8MSW9
resolver
uniprot_sec
Q59EN1
resolver
uniprot_sec
Q86XE9
resolver
uniprot_sec
Q9Y6V4
resolver
amino_acid_sequence
MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Microtubule-based anterograde translocator for membranous organelles, such as primary cilium and centriole. Shows a plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation, probably by mediating transport of proteins into primary cilia. Mediates smoothened (SMO) translocation into primary cilia in response to hedgehog morphogens. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole. {ECO:0000250|UniProtKB:P28741}.
uniprot
proteins
mass_dalton
80041
uniprot
proteins
protein_family
Kinesin II subfamily
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
10548469
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19934039
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20643351
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22261744
uniprot
proteins
pubmed
23386061
uniprot
proteins
pubmed
27072130
uniprot
proteins
sequence_length
699
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}. Cell projection, cilium {ECO:0000250|UniProtKB:P28741}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23386061}. Note=Localizes to the subdistal appendage region of the centriole. {ECO:0000269|PubMed:23386061}.
uniprot
proteins