Mpzl3
entrez
319742
canonical
uniprot
Q3V3F6
canonical
ensembl
ENSMUSG00000070305
resolver
ensp
ENSMUSP00000110312
resolver
genesymbol
Mpzl3
resolver
uniprot
A5H7F1
resolver
uniprot_entry
MPZL3_MOUSE
resolver
uniprot_sec
A5H7F1
resolver
amino_acid_sequence
MQLARGTVGGRGCALFPLLSILVVQGARIVLSLEISADAHVRGYVGEKIKLKCTFKSSSDVTDKLTIDWTYRPPSSSRTESIFHYQSFQYPTTAGTFRDRISWAGNVYKGDASISISNPTLKDNGTFSCAVKNPPDVYHNIPLTELTVTERGFGTMLSSVALLSILVFVPSAVVVILLLVRMGRKATGVQKRSRSGYKKSSIEVSDDTDQEDSNDCMTRLCVRCAECLDSDYEEEAY
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Mpzl3 are the cause of rough coat (rc) phenotype, an autosomal-recessive mutation, arose spontaneously in C57BL/6J mice. Rc mice develop severe skin and hair abnormalities, including cyclic and progressive hair loss and sebaceous gland hypertrophy.
uniprot
proteins
function
FUNCTION: Mediates homophilic cell-cell adhesion. {ECO:0000250}.
uniprot
proteins
mass_dalton
26058
uniprot
proteins
protein_family
Myelin P0 protein family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17273165
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
237
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 160..180; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins