Arfip2
entrez
293344
canonical
uniprot
Q6AY65
canonical
ensembl
ENSRNOG00000018440
resolver
ensembl
ENSRNOG00055024349
resolver
ensembl
ENSRNOG00060018218
resolver
ensembl
ENSRNOG00065031850
resolver
ensp
ENSRNOP00000025159
resolver
ensp
ENSRNOP00000081982
resolver
ensp
ENSRNOP00055034106
resolver
ensp
ENSRNOP00060025449
resolver
ensp
ENSRNOP00065045135
resolver
enst
ENSRNOT00000025159
resolver
enst
ENSRNOT00000111341
resolver
enst
ENSRNOT00055041869
resolver
enst
ENSRNOT00060031364
resolver
enst
ENSRNOT00065054870
resolver
genesymbol
Arfip2
resolver
uniprot
A0A8I5ZUX2
resolver
uniprot_entry
A0A8I5ZUX2_RAT
resolver
uniprot_entry
ARFP2_RAT
resolver
amino_acid_sequence
MTDGILGKAATMEIPIHGNGEAGQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTSPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQTHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ
uniprot
proteins
function
FUNCTION: Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG. {ECO:0000250|UniProtKB:P53365}.
uniprot
proteins
mass_dalton
37773
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:P53365}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:P53365}.
uniprot
proteins