TMEM25
entrez
84866
canonical
uniprot
Q86YD3
canonical
ensembl
ENSG00000149582
resolver
ensp
ENSP00000278959
resolver
ensp
ENSP00000315635
resolver
ensp
ENSP00000346237
resolver
ensp
ENSP00000352924
resolver
ensp
ENSP00000411882
resolver
ensp
ENSP00000416071
resolver
ensp
ENSP00000431205
resolver
ensp
ENSP00000431548
resolver
ensp
ENSP00000601678
resolver
ensp
ENSP00000601679
resolver
ensp
ENSP00000601681
resolver
ensp
ENSP00000617326
resolver
ensp
ENSP00000617328
resolver
ensp
ENSP00000646864
resolver
ensp
ENSP00000646865
resolver
ensp
ENSP00000646866
resolver
ensp
ENSP00000646867
resolver
ensp
ENSP00000711185
resolver
ensp
ENSP00000711186
resolver
ensp
ENSP00000711189
resolver
ensp
ENSP00000711191
resolver
ensp
ENSP00000774071
resolver
enst
ENST00000533102
resolver
genesymbol
TMEM25
resolver
hgnc
HGNC:25890
resolver
uniprot
A8K8J4
resolver
uniprot
B0YJA6
resolver
uniprot
B0YJA7
resolver
uniprot
B0YJA9
resolver
uniprot
B7Z1M8
resolver
uniprot
E9PKP3
resolver
uniprot
G5E9U4
resolver
uniprot
Q6UW89
resolver
uniprot
Q86UA7
resolver
uniprot
Q8NBL5
resolver
uniprot
Q96KA6
resolver
uniprot
Q96MW9
resolver
uniprot_entry
B7Z1M8_HUMAN
resolver
uniprot_entry
E9PKP3_HUMAN
resolver
uniprot_entry
TMM25_HUMAN
resolver
uniprot_sec
A8K8J4
resolver
uniprot_sec
B0YJA6
resolver
uniprot_sec
B0YJA7
resolver
uniprot_sec
B0YJA9
resolver
uniprot_sec
G5E9U4
resolver
uniprot_sec
Q6UW89
resolver
uniprot_sec
Q86UA7
resolver
uniprot_sec
Q8NBL5
resolver
uniprot_sec
Q96KA6
resolver
uniprot_sec
Q96MW9
resolver
amino_acid_sequence
MALPPGPAALRHTLLLLPALLSSGWGELEPQIDGQTWAERALRENERHAFTCRVAGGPGTPRLAWYLDGQLQEASTSRLLSVGGEAFSGGTSTFTVTAHRAQHELNCSLQDPRSGRSANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPPANVTWIDQDGPVTVNTSDFLVLDAQNYPWLTNHTVQLQLRSLAHNLSVVATNDVGVTSASLPAPGLLATRVEVPLLGIVVAAGLALGTLVGFSTLVACLVCRKEKKTKGPSRHPSLISSDSNNLKLNNVRLPRENMSLPSNLQLNDLTPDSRAVKPADRQMAQNNSRPELLDPEPGGLLTSQGFIRLPVLGYIYRVSSVSSDEIWL
uniprot
proteins
function
FUNCTION: In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability. {ECO:0000269|PubMed:31424425}.
uniprot
proteins
mass_dalton
39285
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
31424425
uniprot
proteins
sequence_length
366
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: Late endosome {ECO:0000250|UniProtKB:Q9DCF1}. Lysosome {ECO:0000250|UniProtKB:Q9DCF1}.
uniprot
proteins
transmembrane_region
TRANSMEM 233..253; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins