A2AJ76
uniprot
A2AJ76
canonical
amino_acid_sequence
MTPGAQLLPLLVAISTAVAAVVTSDAPTKTLSPATGDATLAFVFDVTGSMWDDLMQVIDGASRILERSLSSRSRVIANYALVPFHDPDIGPVTLTADPVVFQRELRELYVQGGGDCPEMSVGAIKAAVEVANPGSFIYVFSDARAKDYHKKKELLQLLQLKQSQVVFVLTGDCGDRTHPGYLVFEEIASTSSGQVFQLDKQQVSEVLKWVESAIQASKVHLLSADHEEEGEHTWRIPFDPSLKEVTIALSGPGPEIEVRDPLGRVLQTDEGLNVLLNIPDSAKVVAFKPEHPGLWAIKVYSSGRHSVRISGISNINFRAGFSMQPSLDLNHTIEWPLQGVPISLVINSTGLQAPGHLESVELSHSSGRSLLTLPTQLLSNGSTHQLWAGPPFHVPKERFYLKVKGKDHEGNPLLRVSGVSYSAVAPGVPLVSMAPKIHGYLQQPLLVSCSVYSTLPFQLQLQRDGERLGEERYFQESGNSSWEIPRASKAEEGTYQCIAVSRAGSGRASAQIVITDPPPQLVPGPNVTVSPGETAILSCQVLGETPYNLTWVRDWRALPATTGRISQLSDLSLEVRSIIPTDGGQYQCVASNPNGVTRATTWLLVREAPQVSINARSQRFSQGVEVRVSCSASGYPTPHISWSREGLALPEDSRIHVDAQGTLIIQGLAPEDAGNYSCQATNEVGTDEETVTLYYTDPPSVSAVNAVVLTAVGEEAVLLCAASGVPPPRVIWYRGGLEVILAPGDSRSGTLRIPEAQERDAGLYTCKAVNELGDASAEIQLVVGNAPRLTDPPQDVTVELGKSVFLTCRATGRPPPIVTWRRGDGQALEPGRGSRTGQRDSGVLVFERVSLEDQAPYVCEARNVFGKAQAEARLVVTGHAPPQIANSASVVRVLEGQPVSLTCVILAGRPLPERRWLKAGSPLPPGNRHAVRADGSLHLDRALQEDAGRYSCVATNVAGSQHRDVELVVQVPPRIHPTSTHHVTNEGVPASLPCIASGVPTPKITWTKETNALTTSGHYSVSRNGTLVIVQPSPQDAGAYVCTATNSVGFSSQEMWLSVNTKPMIKMNGSQAVDVPLRVTVKAGEEVTLDCEAQGSPTPLLTWTKDANPLLPVTNRYELLPSGSLRLAQAQVGDNGLYGCTASNPAGATSRRYVLRVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMALMGEGAQGSVHFAAVKTSDAGLYRCEASNSAGTDTWKLELLVLEPPHWGTDETKSLLERVAGENASLPCPAQGTPKPRITWRRGPSSEPLNGRPDVAVLDEGSLFLSSVSLADSGEYECQATNEVGSASRRAKLVVYVPPSIREEGHITNVSGLAGQPLTLECDINGFPAPEVAWLKDGQLVGDSGGGWDGEEASGHRLLDGSRSLHFPRIQESHSGLYSCQAENQAGSAQRDFNLAVFIPPSLLGAGAAQEVLGLAGADVTLECQTSGVPTPQVEWTKDGQPILPGDPHILLQEDGQVLRIISSHLGDEGQYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEARGMPSPAITWYKDGTLLAPSSEVVYSKGGRQLQLVKAQPSDAGLYTCQASNPAGITKKSTSLEVYVPPTIEGADGGPYLVQAVAGRPVALECVARGHPPPTISWQHEGLPVVDSNGTWLEAGGALQLENPGEASGGLYSCVASSPAGEAVLQYSVEMQVPPQLLVAEGMGQVTATVGQSLDLPCQASGSPVPTIQWLQNGRPAEELAGVQLASQGTILHISHVELNHSGLFACQATNEAGTAGAEVEVSVHGKQVSVNLGASFSAHHWWGEPHSPFPATCNPPVCRHWSAYPKPSLVERWRGRGNLRGQPSGTVREPGLTLLSQIEKADLRDEGVYTCSATNLAGESKKDVTLKVLVPPNIEPGPVNKVVLENASVTLECLASGVPPPDVSWFKGRQPISTQRRVIVSADGRVLHIERVQLSDAGSYRCVATNVAGSAGLKYGLRVNVPPRITLPPNLPGPVLLGTPFRLTCNATGTPRPTLIWLKDGNPVSPEGIPGLKVFPGGQVLTVASARASDSGSYSCVAVSAVGEDRRDVILQVHMPPSILGEELNMSVVVNESVTLECQSHAVPPPVLRWQKDGRPLEPHPGIRLSADKALLEVDRAAVWDAGHYTCEAINQAGRSEKHFNLHVWVPPAFPSKEPYTLTVTEGQTARLSCDCQGIPFPKISWRKDGQPLPGEGDSLEQVLAVGRLLYLGQAQSAQEGTYTCECSNAAGTSSQEQSLEVLVPPQVTGLWEPLTTVSVIQDGNTTLACNATGKPLPVVTWQRDGQPVSVEPGLRLQNQNHSLHVERAQASHAGGYSCVAENTAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSFTLLCEAAGVPAPTVQWFQEGQPISPREGTYLLAGGWMLKMTQAQEQDRGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVPEGQTAQLECNATGHPPPKVTWFKDGQSLTVEDPYEMSPDGAFLWIPQANLSNAGHYSCIASNAVGEKTKHTQLSVLVVPTILGVPEKNANEEVTVTINNPISLICEALAFPSPNITWMKDGSPFEASKNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEATKNYHVEVLIPPSISKDDPLGEVSVKEVKTKVNSSLTLECECWATPPPSISWYKDGRPVTPSHRLSVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKMGDVDAGFEPLPHEEEAQGRVTEYREIVENNPAYLYCDTNAIPPPELTWYREGQPLSAADGVSVLQGGRILQLPLVQAEDAGRYSCKAANEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAVSWFQNGLPVSPSPRLQVLEEGQVLKVATAEVADAASYMCVAENQAGSAEKLFTLKVQVPPQISDWTTSQLTATLNSSVSLPCEVYAHPNPEVTWYKDGQPLSLGQEAFLLPGTHTLRLARAQPADSGTYLCEALNAAGRDQKMVQLNVLVPPSFKQAPGGPQEAIQVRAGDKAILSCETDSLPEPAVTWFKDQQPLALGQRIQGLQGGQTLEILDSQASDKGVYSCKVSNTAGEAIRTFVLAIQVPPTFEKPERETVNQVAGRTLVLACDVSGIPAPTVTWLKDRLPVESSVVHGVVSRGGRLQLSHLQPAQAGTYTCVAENAQAEARKDFVVSVLVPPQIQDSGMAQEHNVLEKQEIRLHCEAEGQPPPDITWLKDGGLLDQHVGPHLRFYLDGSTLVLKGLRTADSGAYTCVAHNPAGEDARLHTVNVLVPPTIKQQAGDTGTLVSRTGELVTMVCPVQGSPPIHVSWLKDGLPLPLSQRTLLHSSGRTLRISQVQLADSGVFTCVAASPAGVADRNFTLLVLVPPILEPVEFQNNVMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQSLEQGPGLKLESVSVGDAGTYSCTAASEAGEARRHFQLTVMDPPHIEESGETSELSLTPGAHLELLCEARGIPPPNITWHKDGQALRRTENDSQAGRVLRVDNAGLYTCLAESPAGEVEKSFRVRVQAPPNVVGPRGPRSVVGLAPGQLILECSVEAEPAPEIEWHRGGVLLQADAHTHFPEQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRVEIHTAPTIQSGPNTVNVSVNRTTLLPCQTHGVPTPLVSWRKDGIPLHPGSPRLEFLPEGSLRIHPVLAQDAGHYLCLASNSAGSDRKGLDLRVFEPPAIAPGPSNLTLTAYSPASLPCEARGSPKPLVTWWKDGQKLDLRLQQGAYRLLPSNALFLTAPSPQDSAQFECVVSNEVGESRRRYQVTVHVPPTIADDQTHFTVTRMAPVILTCHSTGSPTPAVSWSKAGTQLGARGSGYRILPSGALEIERALPLHAGRYTCTARNSAGVARKHMVLTVQASPVVKPLPSVVQVVASEEVLLPCEASGIPQPMVIWQKEGLSIPEGAHMQVLPSGQLRIMHASPEDAGNYFCIAQNSVGSAMAKTRLVVQVPPVIENGLPDLSTIEGSHALLPCTAKGSPEPAITWEKDGHLVSGAEGKFTLQPSGELLVKNSEGQDAGTYICTAENAVGRARRRVHLTILTLPVLTTLPGDRSLRLGDRLWLRCVARGSPTPRIGWTINDQPVTEGVSEQDGGSTLQRAAVTREDSGTYTCWAENRVGRVQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLHCVVRGDPAPDIHWTKDGLPLPISRLHFQLQNGSLTILRTKMDDAGRYQCLAVNEMGTVKKVVTVVLQSAPVFQVEPQDVTVRSGVDVELRCRATGEPVPTIEWLRAGRPLQAGRKLRALPDGSLWLEHVEAGDAGVYECVAHNHLGSVTAKALLAVRGEPRGSRGSMTGVINGQEFGMATLNISVLQQGSSEAPTIWSSISQVPASVGPLMRVLVVTIAPIYWALARESGEALNGYSLTGGSFQQESQMEFSTGELLTMTQVARGLDPDGLLLVDMKINGMIPESLADGDLRVQDFQEHYVQTGPGQLFAGSTQRFLHDSLPASLRCNHSIQYDETRGLQPQLVQHLRASSISSAFDPEAEALNFQLTTALQTEENEVGCPEGFEPDVQGAFCVDKDECSGGPSPCSHTCRNAPGHFSCSCPTGFSLAWDHRNCRDVDECAGNTHLCQEEQRCVNLLGSYNCLASCRPGFRVTADGSNCEDVDECLEQLDECHYNQLCENTPGGHHCGCPRGYRQQGHSLPCLDINECLQLPTPCVYQCQNLQGSYRCLCPPGQTLLRDGRTCIPLERNRQNITIVSHRSPFGPWLRSRVPRPSSSYHTWVSLRPGSGALNSVGRAWCPPGFIRQDGVCADLDECRVRSLCQHACQNTEGSYYCLCPSGYRLLPSGKNCQDINECEEDGIECGPGQMCFNTRGSFQCVDTPCPTTYRQGSSPGTCFRRCSQDCSASGPSTLQYRLLPLPLGVRAHHDVARLAAFSEAGIPANRTELTVLEPDPRSPFALRQLRAGQGAVYTRRALTRAGLYRLTVRAAAPRHQSVYILLIAVSPYPY
uniprot
proteins
mass_dalton
547198
uniprot
proteins
post_translational_modification
PTM: Reported to be phosphorylated; however as this position is extracellular, the in vivo relevance is unsure.
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17015624
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21215633
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
32035013
uniprot
proteins
pubmed
34504132
uniprot
proteins
sequence_length
5100
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17015624}. Cleavage furrow {ECO:0000269|PubMed:21215633}. Note=The antibody used in PubMed:17015624 and PubMed:21215633 to determine subcellular location does not distinguish between HMCN1 and HMCN2. {ECO:0000269|PubMed:17015624, ECO:0000269|PubMed:21215633}.
uniprot
proteins