Rab20
entrez
19332
canonical
uniprot
P35295
canonical
ensembl
ENSMUSG00000031504
resolver
ensp
ENSMUSP00000033900
resolver
enst
ENSMUST00000033900
resolver
genesymbol
Rab20
resolver
uniprot
Q3TPA7
resolver
uniprot_entry
Q3TPA7_MOUSE
resolver
uniprot_entry
RAB20_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. Regulated by GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity. Inhibited by GDP dissociation inhibitors (GDIs). {ECO:0000250|UniProtKB:P62820}.
uniprot
proteins
amino_acid_sequence
MRKPDGKIVLLGDMNVGKTSLLQRYMERRFPDTVSTVGGAFYLKQWRSFNISIWDTAGREQFHGLGSLYCRGAAAIILTYDVNHPQSLFELEDRFLGLTETANNDCLFAIVGNKVDLTSERDTEGGEKEGPASGKVGSCVSTKVPKQVQPEDAVALYKKILKYKMLDEREMPAAEQMCFETSAKTGYNVDLLFETLFDLVVPMIMRQRAEESDQTVDIASCKTPKQTRSGCCA
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium. Plays a role in the fusion of phagosomes with lysosomes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
25989
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
1555775
uniprot
proteins
pubmed
7706395
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:Q9NX57}. Cytoplasmic vesicle, phagosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus {ECO:0000250|UniProtKB:Q9NX57}. Note=Recruited to phagosomes containing S.aureus or Mycobacterium (By similarity). Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (PubMed:7706395). {ECO:0000250|UniProtKB:Q9NX57, ECO:0000269|PubMed:7706395}.
uniprot
proteins