Kcnj8
entrez
25472
canonical
uniprot
Q63664
canonical
ensembl
ENSRNOG00000013463
resolver
ensembl
ENSRNOG00055010196
resolver
ensembl
ENSRNOG00060007578
resolver
ensembl
ENSRNOG00065005793
resolver
ensp
ENSRNOP00000018057
resolver
ensp
ENSRNOP00055013854
resolver
ensp
ENSRNOP00060009473
resolver
ensp
ENSRNOP00065006121
resolver
enst
ENSRNOT00000018057
resolver
enst
ENSRNOT00055017217
resolver
enst
ENSRNOT00060012503
resolver
enst
ENSRNOT00065008658
resolver
genesymbol
Kcnj8
resolver
uniprot
Q9JM49
resolver
uniprot
Q9JM50
resolver
uniprot_entry
KCNJ8_RAT
resolver
uniprot_sec
Q9JM49
resolver
uniprot_sec
Q9JM50
resolver
amino_acid_sequence
MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKGITEKSGLESAVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQQDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLVNQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVRVAAPRCSARELDEKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRSNSIRRNNSSLMVPKVQFMTPEGNQCPSES
uniprot
proteins
function
FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium (PubMed:7890693). Can form a sulfonyllurea-sensitive but ATP-insensitive potassium channel with ABCC9 (By similarity). {ECO:0000250|UniProtKB:P97794, ECO:0000269|PubMed:7890693}.
uniprot
proteins
mass_dalton
47963
uniprot
proteins
protein_family
Inward rectifier-type potassium channel (TC 1.A.2.1) family
uniprot
proteins
protein_family
KCNJ8 subfamily
uniprot
proteins
pubmed
7890693
uniprot
proteins
sequence_length
424
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 70..94; /note="Helical; Name=M1"; /evidence="ECO:0000250"; TRANSMEM 155..176; /note="Helical; Name=M2"; /evidence="ECO:0000250
uniprot
proteins