PPFIA2
entrez
8499
canonical
uniprot
O75334
canonical
ensembl
ENSG00000139220
resolver
ensp
ENSP00000327416
resolver
ensp
ENSP00000385093
resolver
ensp
ENSP00000438337
resolver
ensp
ENSP00000445532
resolver
ensp
ENSP00000447273
resolver
ensp
ENSP00000447868
resolver
ensp
ENSP00000449338
resolver
ensp
ENSP00000449558
resolver
ensp
ENSP00000450298
resolver
ensp
ENSP00000450337
resolver
enst
ENST00000550359
resolver
enst
ENST00000550584
resolver
genesymbol
PPFIA2
resolver
hgnc
HGNC:9246
resolver
uniprot
B3KVT5
resolver
uniprot
B3KXA0
resolver
uniprot
B7Z2A6
resolver
uniprot
B7Z3U9
resolver
uniprot
B7Z663
resolver
uniprot
B7Z7Y5
resolver
uniprot
B7ZKZ5
resolver
uniprot
E7ERB8
resolver
uniprot
E7ETG6
resolver
uniprot
F8VP68
resolver
uniprot
G3V200
resolver
uniprot
H0YHK3
resolver
uniprot
Q2M3G8
resolver
uniprot_entry
B7Z7Y5_HUMAN
resolver
uniprot_entry
G3V200_HUMAN
resolver
uniprot_entry
H0YHK3_HUMAN
resolver
uniprot_entry
LIPA2_HUMAN
resolver
uniprot_sec
B3KVT5
resolver
uniprot_sec
B3KXA0
resolver
uniprot_sec
B7Z2A6
resolver
uniprot_sec
B7Z3U9
resolver
uniprot_sec
B7Z663
resolver
uniprot_sec
B7ZKZ5
resolver
uniprot_sec
E7ERB8
resolver
uniprot_sec
E7ETG6
resolver
uniprot_sec
F8VP68
resolver
uniprot_sec
Q2M3G8
resolver
amino_acid_sequence
MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLAGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSYHNDARSSLSVSLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESDDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC
uniprot
proteins
function
FUNCTION: Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines (PubMed:30021165). {ECO:0000269|PubMed:30021165, ECO:0000269|PubMed:9624153}.
uniprot
proteins
mass_dalton
143291
uniprot
proteins
protein_family
Liprin family
uniprot
proteins
protein_family
Liprin-alpha subfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
30021165
uniprot
proteins
pubmed
9624153
uniprot
proteins
sequence_length
1257
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:9624153}. Cell surface {ECO:0000269|PubMed:9624153}. Cell projection, dendritic spine {ECO:0000269|PubMed:30021165}. Note=Colocalizes with PTPRF at the cell surface.
uniprot
proteins