LRFN2
entrez
57497
canonical
uniprot
Q9ULH4
canonical
ensembl
ENSG00000156564
resolver
ensp
ENSP00000345985
resolver
enst
ENST00000338305
resolver
genesymbol
LRFN2
resolver
genesymbol_syn
KIAA1246
resolver
genesymbol_syn
SALM1
resolver
hgnc
HGNC:21226
resolver
uniprot
A5PKU3
resolver
uniprot
Q5SYP9
resolver
uniprot_entry
LRFN2_HUMAN
resolver
uniprot_sec
A5PKU3
resolver
uniprot_sec
Q5SYP9
resolver
amino_acid_sequence
METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRAPWRIPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV
uniprot
proteins
function
FUNCTION: Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
84731
uniprot
proteins
mutagenesis
MUTAGEN 787..789; /note="Missing: Loss of DLG1-, DLG3- and DLG4-binding."; /evidence="ECO:0000269|PubMed:16630835
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
LRFN family
uniprot
proteins
pubmed
10574462
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16630835
uniprot
proteins
sequence_length
789
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. Synapse. Postsynaptic cell membrane {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 535..555; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins