POLR2E
entrez
5434
canonical
uniprot
P19388
canonical
ensembl
ENSG00000099817
resolver
ensp
ENSP00000464739
resolver
ensp
ENSP00000478303
resolver
ensp
ENSP00000480562
resolver
ensp
ENSP00000485021
resolver
ensp
ENSP00000555954
resolver
ensp
ENSP00000555964
resolver
ensp
ENSP00000555965
resolver
ensp
ENSP00000555970
resolver
ensp
ENSP00000555973
resolver
ensp
ENSP00000555975
resolver
ensp
ENSP00000555976
resolver
ensp
ENSP00000634468
resolver
ensp
ENSP00000634469
resolver
enst
ENST00000586746
resolver
enst
ENST00000612655
resolver
enst
ENST00000615234
resolver
enst
ENST00000885895
resolver
enst
ENST00000885905
resolver
enst
ENST00000885906
resolver
enst
ENST00000885911
resolver
enst
ENST00000885914
resolver
enst
ENST00000885916
resolver
enst
ENST00000885917
resolver
enst
ENST00000964410
resolver
enst
ENST00000964411
resolver
genesymbol
POLR2E
resolver
hgnc
HGNC:9192
resolver
uniprot
B2R6L4
resolver
uniprot
B4DJ89
resolver
uniprot
D6W5Y1
resolver
uniprot
E5KT65
resolver
uniprot
O43380
resolver
uniprot
Q6PIH5
resolver
uniprot
Q9BT06
resolver
uniprot_entry
B4DJ89_HUMAN
resolver
uniprot_entry
E5KT65_HUMAN
resolver
uniprot_entry
RPAB1_HUMAN
resolver
uniprot_sec
B2R6L4
resolver
uniprot_sec
D6W5Y1
resolver
uniprot_sec
O43380
resolver
uniprot_sec
Q6PIH5
resolver
uniprot_sec
Q9BT06
resolver
amino_acid_sequence
MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSEGRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAGRYITYRLVQ
uniprot
proteins
function
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPABC1 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. {ECO:0000250|UniProtKB:P20434, ECO:0000269|PubMed:16809778, ECO:0000269|PubMed:20413673, ECO:0000269|PubMed:27193682, ECO:0000269|PubMed:30190596, ECO:0000269|PubMed:34671025, ECO:0000269|PubMed:34887565, ECO:0000269|PubMed:36271492, ECO:0000269|PubMed:9852112}.
uniprot
proteins
mass_dalton
24551
uniprot
proteins
protein_family
Archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16809778
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20413673
uniprot
proteins
pubmed
2071613
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
27193682
uniprot
proteins
pubmed
2753903
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
30190596
uniprot
proteins
pubmed
31738558
uniprot
proteins
pubmed
33335104
uniprot
proteins
pubmed
33558764
uniprot
proteins
pubmed
33558766
uniprot
proteins
pubmed
33674783
uniprot
proteins
pubmed
34671025
uniprot
proteins
pubmed
34675218
uniprot
proteins
pubmed
34887565
uniprot
proteins
pubmed
36271492
uniprot
proteins
pubmed
7828586
uniprot
proteins
pubmed
9819440
uniprot
proteins
pubmed
9852112
uniprot
proteins
sequence_length
210
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:33335104, ECO:0000269|PubMed:9852112}. Nucleus, nucleolus {ECO:0000305|PubMed:34887565, ECO:0000305|PubMed:36271492}.
uniprot
proteins