Kcnk12
entrez
64119
canonical
uniprot
Q9ERS1
canonical
ensembl
ENSRNOG00000016110
resolver
ensembl
ENSRNOG00055019034
resolver
ensembl
ENSRNOG00060003846
resolver
ensembl
ENSRNOG00065007824
resolver
ensp
ENSRNOP00000021570
resolver
ensp
ENSRNOP00055026277
resolver
ensp
ENSRNOP00060004810
resolver
ensp
ENSRNOP00065008972
resolver
enst
ENSRNOT00000021570
resolver
enst
ENSRNOT00055032457
resolver
enst
ENSRNOT00060006422
resolver
enst
ENSRNOT00065012258
resolver
genesymbol
Kcnk12
resolver
uniprot_entry
KCNKC_RAT
resolver
amino_acid_sequence
MSSRSPRPPPRRCRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLACCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCTRCCPAPGAPLSRRNAITPGSRLRRRLAALGTDPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR
uniprot
proteins
function
FUNCTION: K(+) channel subunit that may homo- and heterodimerize to form functional channels with distinct regulatory and gating properties. Can heterodimerize with KCNK13 subunit to conduct K(+) outward rectifying currents at the plasma membrane. The homodimers are mainly retained in the endoplasmic reticulum compartment and may be targeted to the cell surface upon phosphorylation or other activation signals yet to be elucidated. {ECO:0000250|UniProtKB:Q9HB15}.
uniprot
proteins
mass_dalton
46965
uniprot
proteins
protein_family
Two pore domain potassium channel (TC 1.A.1.8) family
uniprot
proteins
pubmed
11060316
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9HB15}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9HB15}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 145..165; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 213..233; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 282..302; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins