PDZRN3
entrez
23024
canonical
uniprot
Q9UPQ7
canonical
ensembl
ENSG00000121440
resolver
ensp
ENSP00000263666
resolver
ensp
ENSP00000418168
resolver
ensp
ENSP00000418484
resolver
ensp
ENSP00000418624
resolver
ensp
ENSP00000787860
resolver
enst
ENST00000462146
resolver
enst
ENST00000466780
resolver
enst
ENST00000479530
resolver
genesymbol
PDZRN3
resolver
genesymbol_syn
KIAA1095
resolver
genesymbol_syn
LNX3
resolver
genesymbol_syn
SEMCAP3
resolver
hgnc
HGNC:17704
resolver
uniprot
A7MCZ6
resolver
uniprot
B7Z2I8
resolver
uniprot
B7Z5Q3
resolver
uniprot
B7Z5X9
resolver
uniprot
B7ZAG0
resolver
uniprot
E7ENB6
resolver
uniprot
F6VZV2
resolver
uniprot
Q8N2N7
resolver
uniprot
Q96CC2
resolver
uniprot
Q9NSQ2
resolver
uniprot_entry
B7Z2I8_HUMAN
resolver
uniprot_entry
B7Z5Q3_HUMAN
resolver
uniprot_entry
B7Z5X9_HUMAN
resolver
uniprot_entry
B7ZAG0_HUMAN
resolver
uniprot_entry
E7ENB6_HUMAN
resolver
uniprot_entry
F6VZV2_HUMAN
resolver
uniprot_entry
PZRN3_HUMAN
resolver
uniprot_sec
A7MCZ6
resolver
uniprot_sec
Q8N2N7
resolver
uniprot_sec
Q96CC2
resolver
uniprot_sec
Q9NSQ2
resolver
amino_acid_sequence
MGFELDRFDGDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLSAKELNHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRHAGCGQVLLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGALHKALKKEALRAGKREKSLVAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGGKGEETKSLTLVLHRDSGSLGFNIIGGRPSVDNHDGSSSEGIFVSKIVDSGPAAKEGGLQIHDRIIEVNGRDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPPSESQLVDTGTQTDITFEHIMALTKMSSPSPPVLDPYLLPEEHPSAHEYYDPNDYIGDIHQEMDREELELEEVDLYRMNSQDKLGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASVLQQKKHDEDGGTTDTATILSNQHEKDSGVGRTDESTRNDESSEQENNGDDATASSNPLAGQRKLTCSQDTLGSGDLPFSNESFISADCTDADYLGIPVDECERFRELLELKCQVKSATPYGLYYPSGPLDAGKSDPESVDKELELLNEELRSIELECLSIVRAHKMQQLKEQYRESWMLHNSGFRNYNTSIDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRAAEGISCPSSEGAVGTTEAYGPASKNLLSITEDPEVGTPTYSPSLKELDPNQPLESKERRASDGSRSPTPSQKLGSAYLPSYHHSPYKHAHIPAHAQHYQSYMQLIQQKSAVEYAQSQMSLVSMCKDLSSPTPSEPRMEWKVKIRSDGTRYITKRPVRDRLLRERALKIREERSGMTTDDDAVSEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQQAADDRKEMNILELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation. {ECO:0000250|UniProtKB:Q69ZS0}.
uniprot
proteins
mass_dalton
119596
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
post_translational_modification
PTM: Auto-ubiquitinated. {ECO:0000250}.
uniprot
proteins
pubmed
10470851
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15010864
uniprot
proteins
pubmed
15305371
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17118964
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
1066
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Synapse {ECO:0000250|UniProtKB:Q69ZS0}. Cytoplasm {ECO:0000250|UniProtKB:E7FDW2}. Note=Localizes to the postsynaptic region of neuromuscular junctions. {ECO:0000250|UniProtKB:Q69ZS0}.
uniprot
proteins