Actrt1
entrez
302796
canonical
uniprot
Q5XIK1
canonical
ensembl
ENSRNOG00000003456
resolver
ensembl
ENSRNOG00055015363
resolver
ensembl
ENSRNOG00060021998
resolver
ensembl
ENSRNOG00065011667
resolver
ensp
ENSRNOP00000053759
resolver
ensp
ENSRNOP00055021338
resolver
ensp
ENSRNOP00060031396
resolver
ensp
ENSRNOP00065014493
resolver
enst
ENSRNOT00000004591
resolver
enst
ENSRNOT00055026235
resolver
enst
ENSRNOT00060038096
resolver
enst
ENSRNOT00065018965
resolver
genesymbol
Actrt1
resolver
uniprot_entry
ACTT1_RAT
resolver
amino_acid_sequence
MLNTARLDNPAVIFDNGSGLCKVGISGEIVPRHVINSVVGHPKFNIPSARSNRKRYFVGEEAQCMYDGLYLHYPIERGLVTRWDDMEKLWKDLFEWELGVKPNEQPVFMTEPSLNPRETREKTTEIMFEKFNVPALYLCNHAVGALCASACITGLVLDSGDGVTCTVPIYEGYSLPRAITKLYVAGRDITEHLTRLLLAKGYTFPCILNKAVVDDIKEKLCTVSWGSKDSEKCYQRSLSEYKLPDGNTIQMSDHLCQVPEVLFTPEHLGIHDLGISKMVCNSIMKCDTDIQENLFAEIVLSGGTTLFPGLQDRLLKELEVLAFEGTPIKITASPDRCYSAWIGGSVMTSLTTFKQMWVTAEDFKEYGAFVVQRKCF
uniprot
proteins
function
FUNCTION: Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression. {ECO:0000250|UniProtKB:Q8TDG2}.
uniprot
proteins
mass_dalton
42195
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
376
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8TDG2}. Cytoplasm {ECO:0000250|UniProtKB:Q8TDG2}. Nucleus {ECO:0000250|UniProtKB:Q8TDG2}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q8TDG2}. Note=Both detected in the nucleus and cytoplasm, localizes to the nucleus where it binds chromatin upon stimulation of the Hedgehog pathway. {ECO:0000250|UniProtKB:Q8TDG2}.
uniprot
proteins