Rita1
entrez
288683
canonical
uniprot
Q2KJ10
canonical
ensembl
ENSRNOG00000037720
resolver
ensembl
ENSRNOG00055015385
resolver
ensembl
ENSRNOG00060002266
resolver
ensembl
ENSRNOG00065007739
resolver
ensp
ENSRNOP00000054067
resolver
ensp
ENSRNOP00055021355
resolver
ensp
ENSRNOP00060002436
resolver
ensp
ENSRNOP00065008834
resolver
enst
ENSRNOT00000057242
resolver
enst
ENSRNOT00055026261
resolver
enst
ENSRNOT00060003547
resolver
enst
ENSRNOT00065012105
resolver
genesymbol
Rita1
resolver
genesymbol_syn
Rita
resolver
uniprot_entry
RITA1_RAT
resolver
amino_acid_sequence
MQALHLQHRNPRSYRVKARASYVDETLFGSPTGTRPTLPDFDPPWVQNCNRSRGVSPGPPKVSLAKRDCESPSSRGSTPNLTPRKKNKYRLIGHTPSYCDESLFGSRPQGTSKERSRTAVEDAAKLRTLFWTPPATPRGSHSPRPRETPLRAIHPTGPPRTEPRVATGSQMVSRDGLDAPRSLGQRRSYSLTHLAVPSTGHPASTAPQTNGPWSPRPYTSGATVQSPLVTRKVCSGSVSGPTTPQRGACPQKPKPPWK
uniprot
proteins
function
FUNCTION: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
28148
uniprot
proteins
protein_family
RITA family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
258
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear (By similarity). {ECO:0000250}.
uniprot
proteins