KLRG1
entrez
10219
canonical
uniprot
Q96E93
canonical
ensembl
ENSG00000139187
resolver
ensp
ENSP00000266551
resolver
ensp
ENSP00000349477
resolver
ensp
ENSP00000793597
resolver
genesymbol
KLRG1
resolver
genesymbol_syn
CLEC15A
resolver
genesymbol_syn
MAFA
resolver
genesymbol_syn
MAFAL
resolver
hgnc
HGNC:6380
resolver
uniprot
B7ZAM2
resolver
uniprot
O43198
resolver
uniprot
O75613
resolver
uniprot_entry
KLRG1_HUMAN
resolver
uniprot_sec
B7ZAM2
resolver
uniprot_sec
O43198
resolver
uniprot_sec
O75613
resolver
amino_acid_sequence
MTDSVIYSMLELPTATQAQNDYGPQQKSSSSRPSCSCLVAIALGLLTAVLLSVLLYQWILCQGSNYSTCASCPSCPDRWMKYGNHCYYFSVEEKDWNSSLEFCLARDSHLLVITDNQEMSLLQVFLSEAFCWIGLRNNSGWRWEDGSPLNFSRISSNSFVQTCGAINKNGLQASSCEVPLHWVCKKCPFADQALF
uniprot
proteins
function
FUNCTION: Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. {ECO:0000269|PubMed:19604491}.
uniprot
proteins
mass_dalton
21831
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15879103
uniprot
proteins
pubmed
17617594
uniprot
proteins
pubmed
19604491
uniprot
proteins
pubmed
9765598
uniprot
proteins
pubmed
9842918
uniprot
proteins
sequence_length
195
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19604491}; Single-pass type II membrane protein {ECO:0000269|PubMed:19604491}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins