Htr3b
entrez
57014
canonical
uniprot
Q9JHJ5
canonical
ensembl
ENSMUSG00000008590
resolver
ensp
ENSMUSP00000008734
resolver
enst
ENSMUST00000008734
resolver
genesymbol
Htr3b
resolver
uniprot_entry
5HT3B_MOUSE
resolver
amino_acid_sequence
MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSVWYREVWNDEFLSWNSSLFDEIQEISLPLSALWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNREDIENDKRAFMNDSEWQLLSVSSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTPLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSGQERPLMCLQGDSDAEESRLYLGAPRADVTESPVHQEHRVPSDTLKDFWFQFRSINNSLRTRDQIHQKEVEWLAILYRFDQLLFRIYLAVLGLYTVTLCSLWALWSRM
uniprot
proteins
function
FUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. {ECO:0000250|UniProtKB:O95264}.
uniprot
proteins
mass_dalton
50321
uniprot
proteins
post_translational_modification
PTM: N-glycosylation is required for membrane localization. {ECO:0000250|UniProtKB:O95264}.
uniprot
proteins
protein_family
5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily
uniprot
proteins
protein_family
HTR3B sub-subfamily
uniprot
proteins
protein_family
Ligand-gated ion channel (TC 1.A.9) family
uniprot
proteins
pubmed
10854267
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
437
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic cell membrane {ECO:0000250|UniProtKB:O95264}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O95264}; Multi-pass membrane protein {ECO:0000255}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. {ECO:0000250|UniProtKB:O95264}.
uniprot
proteins
transmembrane_region
TRANSMEM 239..259; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 265..282; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 293..313; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 411..431; /note="Helical; Name=4"; /evidence="ECO:0000255
uniprot
proteins