RPS3A
entrez
6189
canonical
uniprot
P61247
canonical
ensembl
ENSG00000145425
resolver
ensembl
ENSG00000292158
resolver
ensp
ENSP00000346050
resolver
ensp
ENSP00000517921
resolver
ensp
ENSP00000763740
resolver
enst
ENST00000274065
resolver
enst
ENST00000709893
resolver
genesymbol
RPS3A
resolver
genesymbol_syn
FTE1
resolver
genesymbol_syn
MFTL
resolver
hgnc
HGNC:10421
resolver
uniprot
B2R4D4
resolver
uniprot
B7Z3M5
resolver
uniprot
D3DP05
resolver
uniprot
P33443
resolver
uniprot
P49241
resolver
uniprot_entry
B7Z3M5_HUMAN
resolver
uniprot_entry
RS3A_HUMAN
resolver
uniprot_sec
B2R4D4
resolver
uniprot_sec
D3DP05
resolver
uniprot_sec
P33443
resolver
uniprot_sec
P49241
resolver
amino_acid_sequence
MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELHGEGSSSGKATGDETGAKVERADGYEPPVQESV
uniprot
proteins
function
FUNCTION: Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity). {ECO:0000255|HAMAP-Rule:MF_03122, ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:34516797}.
uniprot
proteins
mass_dalton
29945
uniprot
proteins
mutagenesis
MUTAGEN 155; /note="Y->F: Decreased ADP-ribosylation."; /evidence="ECO:0000269|PubMed:29954836
uniprot
proteins
post_translational_modification
PTM: ADP-ribosylated at Tyr-155 by PARP1 in presence of HPF1. {ECO:0000269|PubMed:29954836}.
uniprot
proteins
protein_family
Eukaryotic ribosomal protein eS1 family
uniprot
proteins
pubmed
11823430
uniprot
proteins
pubmed
1398113
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1549582
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17289661
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23636399
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24524803
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
29954836
uniprot
proteins
pubmed
34516797
uniprot
proteins
pubmed
8647443
uniprot
proteins
pubmed
8706699
uniprot
proteins
pubmed
9074506
uniprot
proteins
pubmed
9582194
uniprot
proteins
sequence_length
264
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03122, ECO:0000269|PubMed:17289661, ECO:0000269|PubMed:23636399}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03122}. Nucleus, nucleolus {ECO:0000269|PubMed:34516797}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
uniprot
proteins