Fxyd6
entrez
63847
canonical
uniprot
Q91XV6
canonical
genesymbol
Fxyd6
resolver
genesymbol_syn
Php
resolver
uniprot
Q9JLR4
resolver
uniprot_entry
FXYD6_RAT
resolver
uniprot_sec
Q9JLR4
resolver
amino_acid_sequence
METVLILCSLLAPVVLASAAEKEKEKDPFYYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITTNAAEPQKAEN
uniprot
proteins
function
FUNCTION: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (PubMed:17209044). Decreases the apparent affinity of the transporter for Na(+) (PubMed:17209044). In addition to modulating NKA kinetics, may also function as a regulator of NKA localization to the plasma membrane (PubMed:17209044). {ECO:0000269|PubMed:17209044}.
uniprot
proteins
mass_dalton
10388
uniprot
proteins
protein_family
FXYD family
uniprot
proteins
pubmed
11165386
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17209044
uniprot
proteins
pubmed
26479776
uniprot
proteins
sequence_length
94
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17209044}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 35..57; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q9H0Q3
uniprot
proteins