Tbc1d17
entrez
233204
canonical
uniprot
Q8BYH7
canonical
ensembl
ENSMUSG00000038520
resolver
ensp
ENSMUSP00000048260
resolver
ensp
ENSMUSP00000121546
resolver
ensp
ENSMUSP00000203232
resolver
ensp
ENSMUSP00000203242
resolver
ensp
ENSMUSP00000203247
resolver
enst
ENSMUST00000047085
resolver
enst
ENSMUST00000145959
resolver
genesymbol
Tbc1d17
resolver
uniprot
I6L974
resolver
uniprot
J9JIA9
resolver
uniprot
Q3TCA5
resolver
uniprot_entry
I6L974_MOUSE
resolver
uniprot_entry
J9JIA9_MOUSE
resolver
uniprot_entry
TBC17_MOUSE
resolver
uniprot_sec
Q3TCA5
resolver
amino_acid_sequence
MEGSSYRVVFEKGGVYLHTSARKHQDPDSLIAGVIRVVEKDSDVFLHWAPVEEAGDPTQILFKKDPSRGEPSTSEEEPTFDPGYEPDWAVISTVRPQPHLAEPRKGAEPSSSRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASSPNLPPLPDDEPEPGFEVISCVELGQRPTVERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPVSPMPLSPTRAPLPPPLPEEVIPQPDSSLEILPEDEDGA
uniprot
proteins
function
FUNCTION: Probable GTPase-activating protein that inhibits RAB8A/B function. Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TfR). Involved in regulation of autophagy. {ECO:0000250|UniProtKB:Q9HA65}.
uniprot
proteins
mass_dalton
72860
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
645
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome {ECO:0000250|UniProtKB:Q9HA65}. Cytoplasm {ECO:0000250|UniProtKB:Q9HA65}. Recycling endosome {ECO:0000250|UniProtKB:Q9HA65}. Note=In the presence of optineurin/OPTN, may be recruited to recycling endosomes. {ECO:0000250|UniProtKB:Q9HA65}.
uniprot
proteins