Eno4
entrez
226265
canonical
uniprot
Q8C042
canonical
ensembl
ENSMUSG00000048029
resolver
ensp
ENSMUSP00000144272
resolver
ensp
ENSMUSP00000144656
resolver
ensp
ENSMUSP00000290187
resolver
ensp
ENSMUSP00000290190
resolver
enst
ENSMUST00000200910
resolver
genesymbol
Eno4
resolver
uniprot
A0A0J9YUP0
resolver
uniprot
E9QLA7
resolver
uniprot
Q8BVS9
resolver
uniprot
Q8CFL9
resolver
uniprot_entry
A0A0J9YUP0_MOUSE
resolver
uniprot_entry
ENO4_MOUSE
resolver
uniprot_sec
E9QLA7
resolver
uniprot_sec
Q8BVS9
resolver
uniprot_sec
Q8CFL9
resolver
amino_acid_sequence
MGDEDGGRRGGITRDLQKLKQQAMAYYQENDVPRKLEDLLNSTFYLQPADVYGHLKANYFSKLAKPPSICKIVGKTILDGLGLPTLQVEISCTIQNFPKYICAVAIPTHFEVVENALPEALDAEDSERAQAVNTAVQWINQSITEELWGLVPSNQAEVDHRLRTFFEHKVQEDKERKELEKSQEELVPAPPPVTLPPPPPPPPPPPSKKKGQKAGRRDTLLEKPVSPPEPPEPVLHGSMAIGAVSLAVAKASATLASDPLYLTLASLKHDQEQPSTFSMPLLMGSVLSCGKSSPGKLHLMKEVICIPSPGLTAKQSVELLLEIQKQVNRAMETLPPPKQETKKGHNGSKRAQPPITGKVSHLGCLTINYDAIEQPLLLLQGICSNLGLELGVNFHLAINCAGHELMDYSKGKYEVMVGTHKSAAEMVELYVDLINKYPSIIALIDPFRKEDAEQWDSLYAALASRCYLIAGAASGSVSKLLECRNISTLKSHGLIIKHTNQTTMSDLVEITHLINGKKLLAVFGSTDSESSDDSLVDLAVGFGARFIKLGGLSRGERMTKYNRLLAIEEELIQRGVWGFSEEHNFSFFQEDATATMAEETLGLLDSIFPTEVIEESAKT
uniprot
proteins
ec_number
4.2.1.11
uniprot
proteins
function
FUNCTION: Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis (Probable). Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm (PubMed:23446454). {ECO:0000269|PubMed:23446454, ECO:0000305|PubMed:23446454}.
uniprot
proteins
mass_dalton
67853
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5. {ECO:0000305|PubMed:23446454}.
uniprot
proteins
post_translational_modification
PTM: Synthesized as an approximately 70-kDa precursor, which then undergoes proteolytic cleavage to an approximately 60-kDa enzyme; HOATZ associates directly or indirectly with ENO4 to mediate this process before its transport to mature flagella. {ECO:0000269|PubMed:32248064}.
uniprot
proteins
protein_family
Enolase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23446454
uniprot
proteins
pubmed
32248064
uniprot
proteins
sequence_length
619
uniprot
proteins