Orc1
entrez
18392
canonical
uniprot
Q9Z1N2
canonical
ensembl
ENSMUSG00000028587
resolver
ensp
ENSMUSP00000099805
resolver
enst
ENSMUST00000102744
resolver
genesymbol
Orc1
resolver
genesymbol_syn
Orc1l
resolver
uniprot
A2A8R3
resolver
uniprot
Q3TPY7
resolver
uniprot
Q3UR71
resolver
uniprot_entry
ORC1_MOUSE
resolver
uniprot_entry
Q3TPY7_MOUSE
resolver
uniprot_entry
Q3UR71_MOUSE
resolver
uniprot_sec
A2A8R3
resolver
amino_acid_sequence
MPSYLTRQKTRQTFSWVGRPLPNRKQFQQMYREICMKINDGSEIHIKVGQFVLIQGEDNKKPYVAKLIELFQNGAEVPPKKCARVQWFVRFLEIPVSKRHLLGRSPPAQEIFWYDCSDWDNKINVETIIGPVQVVALAPEEVIPVDQKSEETLFVKLSWNKKDFAPLPPEVLAALREQEDSPEWQKPLKAKIKNVKSPARNTTEQEVKGIKSNHSTSKFHQTPANIVIPNAKKSLELDGLGFTRKPNTRWSKKSSCDSLDYQKTSKRRAAFSETTSPPKKPNKPREIKPSSALETRVKNGQTQPFCAKSSVVLRARNPAMTTTKLGVDNTLSPIRNGLRSSVVPSGGLTPVYIRRKAKEQETHKEPIRTSRVHRKSSLLTLKRIRQQLCLLDGDDRDQEEEESVDSESEEEDEFISSLPTRNSLGQSRTRQTPSKSPQKNPKPRTPHRATPQIRDRNLAVQEPASALEEARLRLHVSAVPDSLPCREQEFQDIYSFVESKLLDGTGGCMYISGVPGTGKTATVHEVIRCLQQAAETDDVPPFQYVEVNGMKLTEPHQVYVQILKKLTGQKATANHAAELLAKQFCGQGSQKETTVLLVDELDLLWTHKQDVMYNLFDWPTHKGAHLIVLTIANTMDLPERIMMNRVSSRLGLTRMSFQPYSHSQLKQILVSRLRNLRAFEDDAIQLVARKVAALSGDARRCLDICRRATEICELSHLRGDSLSLVTVAHLMEAIDEMFSSSYITAIKNSSVVEQSFLRAIIAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSRLGSCRLLLVEPSRNDLLLRVRLNVSQNDVLFALKEE
uniprot
proteins
function
FUNCTION: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
95103
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis. {ECO:0000250}.
uniprot
proteins
protein_family
ORC1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22398447
uniprot
proteins
pubmed
9862484
uniprot
proteins
sequence_length
840
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins