Tmem170a
entrez
66817
canonical
uniprot
Q9D342
canonical
ensembl
ENSMUSG00000031953
resolver
ensp
ENSMUSP00000034431
resolver
ensp
ENSMUSP00000201118
resolver
enst
ENSMUST00000034431
resolver
genesymbol
Tmem170a
resolver
genesymbol_syn
D8Bwg1414e
resolver
genesymbol_syn
Tmem170
resolver
uniprot
A6H6Q8
resolver
uniprot_entry
T170A_MOUSE
resolver
uniprot_sec
A6H6Q8
resolver
amino_acid_sequence
MEREGSGGGGGSAGLLQQILSLKLVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALMSSVFFHVPAGLLALFTLRHHKYGRFMSVSILLMGIVGPITAGILTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVVVVSFLRVLATL
uniprot
proteins
function
FUNCTION: Acts as a regulator of endoplasmic reticulum (ER) and nuclear envelope (NE) morphogenesis. Affects the ratio between tubular ER and ER sheets by promoting sheet formation at the expense of tubules. Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. {ECO:0000250|UniProtKB:Q8WVE7}.
uniprot
proteins
mass_dalton
15224
uniprot
proteins
protein_family
TMEM170 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
144
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8WVE7}; Multi-pass membrane protein {ECO:0000255}. Nucleus envelope {ECO:0000250|UniProtKB:Q8WVE7}.
uniprot
proteins
transmembrane_region
TRANSMEM 51..71; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins