GPR157
entrez
80045
canonical
uniprot
Q5UAW9
canonical
ensembl
ENSG00000180758
resolver
ensp
ENSP00000366628
resolver
ensp
ENSP00000631194
resolver
enst
ENST00000377411
resolver
genesymbol
GPR157
resolver
hgnc
HGNC:23687
resolver
uniprot
A2A334
resolver
uniprot
Q8WWB8
resolver
uniprot
Q9HA73
resolver
uniprot_entry
GP157_HUMAN
resolver
uniprot_sec
A2A334
resolver
uniprot_sec
Q8WWB8
resolver
uniprot_sec
Q9HA73
resolver
amino_acid_sequence
MQPSPPPTELVPSERAVVLLSCALSALGSGLLVATHALWPDLRSRARRLLLFLSLADLLSAASYFYGVLQNFAGPSWDCVLQGALSTFANTSSFFWTVAIALYLYLSIVRAARGPRTDRLLWAFHVVSWGVPLVITVAAVALKKIGYDASDVSVGWCWIDLEAKDHVLWMLLTGKLWEMLAYVLLPLLYLLVRKHINRAHTALSEYRPILSQEHRLLRHSSMADKKLVLIPLIFIGLRVWSTVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANCIMFVLCTRAVRTRLFSLCCCCCSSQPPTKSPAGTPKAPAPSKPGESQESQGTPGELPST
uniprot
proteins
function
FUNCTION: Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger. {ECO:0000250|UniProtKB:Q8C206}.
uniprot
proteins
mass_dalton
36623
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16710414
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium membrane {ECO:0000250|UniProtKB:Q8C206}; Multi-pass membrane protein {ECO:0000255}. Note=Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid. {ECO:0000250|UniProtKB:Q8C206}.
uniprot
proteins
transmembrane_region
TRANSMEM 16..36; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 49..69; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 120..140; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 227..247; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 259..279; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins