AAG1
entrez
1982
canonical
uniprot
P78344
canonical
ensembl
ENSG00000110321
resolver
ensp
ENSP00000340281
resolver
ensp
ENSP00000379778
resolver
ensp
ENSP00000433664
resolver
genesymbol
AAG1
resolver
genesymbol
EIF4G2
resolver
genesymbol_syn
DAP5
resolver
genesymbol_syn
EIF4G2
resolver
hgnc
HGNC:3297
resolver
uniprot
O60877
resolver
uniprot
P78404
resolver
uniprot
Q0VH00
resolver
uniprot
Q0VH01
resolver
uniprot
Q2NKW9
resolver
uniprot
Q2TU89
resolver
uniprot
Q49A79
resolver
uniprot
Q53EU1
resolver
uniprot
Q58EZ2
resolver
uniprot
Q8NI71
resolver
uniprot
Q96C16
resolver
uniprot_entry
IF4G2_HUMAN
resolver
uniprot_entry
Q2TU89_HUMAN
resolver
uniprot_sec
O60877
resolver
uniprot_sec
P78404
resolver
uniprot_sec
Q0VH00
resolver
uniprot_sec
Q0VH01
resolver
uniprot_sec
Q2NKW9
resolver
uniprot_sec
Q49A79
resolver
uniprot_sec
Q53EU1
resolver
uniprot_sec
Q58EZ2
resolver
uniprot_sec
Q8NI71
resolver
uniprot_sec
Q96C16
resolver
amino_acid_sequence
MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGMRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD
uniprot
proteins
function
FUNCTION: Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. {ECO:0000269|PubMed:11511540, ECO:0000269|PubMed:11943866, ECO:0000269|PubMed:9032289, ECO:0000269|PubMed:9049310}.
uniprot
proteins
mass_dalton
102362
uniprot
proteins
post_translational_modification
PTM: Phosphorylation; hyperphosphorylated during mitosis. {ECO:0000269|PubMed:11511540}.
uniprot
proteins
protein_family
Eukaryotic initiation factor 4G family
uniprot
proteins
pubmed
11511540
uniprot
proteins
pubmed
11943866
uniprot
proteins
pubmed
12665801
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17984221
uniprot
proteins
pubmed
18025107
uniprot
proteins
pubmed
18088087
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
9030685
uniprot
proteins
pubmed
9032289
uniprot
proteins
pubmed
9049310
uniprot
proteins
pubmed
9878069
uniprot
proteins
sequence_length
907
uniprot
proteins