Dctn3
entrez
53598
canonical
uniprot
Q9Z0Y1
canonical
ensembl
ENSMUSG00000028447
resolver
ensp
ENSMUSP00000030158
resolver
ensp
ENSMUSP00000130988
resolver
ensp
ENSMUSP00000196872
resolver
enst
ENSMUST00000030158
resolver
enst
ENSMUST00000171641
resolver
genesymbol
Dctn3
resolver
uniprot
E9Q919
resolver
uniprot
Q9CR43
resolver
uniprot
Q9D039
resolver
uniprot_entry
DCTN3_MOUSE
resolver
uniprot_entry
E9Q919_MOUSE
resolver
uniprot_sec
Q9CR43
resolver
uniprot_sec
Q9D039
resolver
amino_acid_sequence
MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNALVPVLDSASIKAVPEHAARLQRLAQIHIQQQDQCVAITEESKALLEGYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAEE
uniprot
proteins
function
FUNCTION: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). Together with dynein may be involved in spindle assembly and cytokinesis (By similarity). {ECO:0000250|UniProtKB:F1SEC0, ECO:0000250|UniProtKB:O75935}.
uniprot
proteins
mass_dalton
20978
uniprot
proteins
protein_family
Dynactin subunit 3 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9786090
uniprot
proteins
sequence_length
186
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O75935}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:O75935}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:O75935}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:O75935}. Cleavage furrow {ECO:0000250|UniProtKB:O75935}. Midbody {ECO:0000250|UniProtKB:O75935}. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells. {ECO:0000250|UniProtKB:O75935}.
uniprot
proteins