FIBCD1
entrez
84929
canonical
uniprot
Q8N539
canonical
ensembl
ENSG00000130720
resolver
ensp
ENSP00000361412
resolver
ensp
ENSP00000361413
resolver
ensp
ENSP00000414501
resolver
ensp
ENSP00000542143
resolver
enst
ENST00000372337
resolver
genesymbol
FIBCD1
resolver
hgnc
HGNC:25922
resolver
uniprot
A3KFJ8
resolver
uniprot
A3KFK0
resolver
uniprot
Q6UXK6
resolver
uniprot
Q96SJ7
resolver
uniprot_entry
A3KFJ8_HUMAN
resolver
uniprot_entry
FBCD1_HUMAN
resolver
uniprot_sec
A3KFK0
resolver
uniprot_sec
Q6UXK6
resolver
uniprot_sec
Q96SJ7
resolver
amino_acid_sequence
MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
uniprot
proteins
function
FUNCTION: Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components. {ECO:0000269|PubMed:19710473, ECO:0000269|PubMed:19892701}.
uniprot
proteins
mass_dalton
50744
uniprot
proteins
mutagenesis
MUTAGEN 393; /note="D->N: Complete loss of binding to acetylated bovine serum albumin and reduced binding to chitin; when associated with A-395."; /evidence="ECO:0000269|PubMed:19892701"; MUTAGEN 395; /note="D->A: Complete loss of binding to acetylated bovine serum albumin and reduced binding to chitin; when associated with N-395."; /evidence="ECO:0000269|PubMed:19892701"; MUTAGEN 405; /note="Y->S: Significantly reduced binding to acetylated bovine serum albumin and loss of binding to chitin; when associated with S-431."; /evidence="ECO:0000269|PubMed:19892701"; MUTAGEN 415; /note="H->G: Complete loss of binding to acetylated bovine serum albumin and chitin."; /evidence="ECO:0000269|PubMed:19892701"; MUTAGEN 431; /note="Y->S: Significantly reduced binding to acetylated bovine serum albumin and loss of binding to chitin; when associated with S-405."; /evidence="ECO:0000269|PubMed:19892701"; MUTAGEN 432; /note="A->V: Complete loss of binding to acetylated bovine serum albumin and chitin."; /evidence="ECO:0000269|PubMed:19892701"; MUTAGEN 443; /note="W->S: Slight reduction in binding to acetylated bovine serum albumin and no effect on binding to chitin."; /evidence="ECO:0000269|PubMed:19892701
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19710473
uniprot
proteins
pubmed
19892701
uniprot
proteins
sequence_length
461
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 34..54; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins