TMED4
entrez
222068
canonical
uniprot
Q7Z7H5
canonical
ensembl
ENSG00000158604
resolver
ensp
ENSP00000289577
resolver
ensp
ENSP00000404042
resolver
ensp
ENSP00000417443
resolver
ensp
ENSP00000617504
resolver
enst
ENST00000289577
resolver
genesymbol
TMED4
resolver
genesymbol_syn
ERS25
resolver
hgnc
HGNC:22301
resolver
uniprot
A4D2K8
resolver
uniprot
B4DFJ4
resolver
uniprot
F8W7F7
resolver
uniprot
Q56VW3
resolver
uniprot
Q7Z432
resolver
uniprot
Q8N2P6
resolver
uniprot_entry
F8W7F7_HUMAN
resolver
uniprot_entry
TMED4_HUMAN
resolver
uniprot_sec
A4D2K8
resolver
uniprot_sec
B4DFJ4
resolver
uniprot_sec
Q56VW3
resolver
uniprot_sec
Q7Z432
resolver
uniprot_sec
Q8N2P6
resolver
amino_acid_sequence
MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
uniprot
proteins
function
FUNCTION: Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
25943
uniprot
proteins
protein_family
EMP24/GP25L family
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12761501
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18326488
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 195..212; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins