Klf15
entrez
66277
canonical
uniprot
Q9EPW2
canonical
ensembl
ENSMUSG00000030087
resolver
ensp
ENSMUSP00000032174
resolver
ensp
ENSMUSP00000109158
resolver
ensp
ENSMUSP00000144808
resolver
ensp
ENSMUSP00000144962
resolver
ensp
ENSMUSP00000187648
resolver
enst
ENSMUST00000032174
resolver
enst
ENSMUST00000113530
resolver
enst
ENSMUST00000203039
resolver
enst
ENSMUST00000203607
resolver
genesymbol
Klf15
resolver
genesymbol_syn
Cklf
resolver
uniprot
Q3UQB0
resolver
uniprot_entry
KLF15_MOUSE
resolver
uniprot_sec
Q3UQB0
resolver
amino_acid_sequence
MVDHLLPVDETFSSPKCSVGYLGDRLASRQPYHMLPSPISEDDSDVSSPCSCASPDSQAFCSCYSAGPGPEAQGSILDFLLSRATLGSGGGSGGIGDSSGPVTWGSWRRASVPVKEEHFCFPEFLSGDTDDVSRPFQPTLEEIEEFLEENMEAEVKEAPENGSRDLETCSQLSAGSHRSHLHPESAGRERCTPPPGGTSGGGAQSAGEGPAHDGPVPVLLQIQPVAVKQEAGTGPASPGQAPESVKVAQLLVNIQGQTFALLPQVVPSSNLNLPSKFVRIAPVPIAAKPIGSGSLGPGPAGLLVGQKFPKNPAAELLKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRAVRAIN
uniprot
proteins
function
FUNCTION: Transcriptional regulator that binds to the GA element of the CLCNKA promoter (By similarity). Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart. Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis. Is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A, GATA4 and MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation (By similarity). Involved in podocyte differentiation. {ECO:0000250, ECO:0000269|PubMed:17438289, ECO:0000269|PubMed:18586263, ECO:0000269|PubMed:20375365, ECO:0000269|PubMed:20566642, ECO:0000269|PubMed:22367544, ECO:0000269|PubMed:22493483, ECO:0000269|PubMed:23999430}.
uniprot
proteins
mass_dalton
44253
uniprot
proteins
protein_family
Sp1 C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
12097321
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17438289
uniprot
proteins
pubmed
18586263
uniprot
proteins
pubmed
20375365
uniprot
proteins
pubmed
20566642
uniprot
proteins
pubmed
22367544
uniprot
proteins
pubmed
22493483
uniprot
proteins
pubmed
23999430
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins