MICOS10
entrez
440574
canonical
uniprot
Q5TGZ0
canonical
ensembl
ENSG00000173436
resolver
ensp
ENSP00000325562
resolver
ensp
ENSP00000478278
resolver
ensp
ENSP00000749943
resolver
enst
ENST00000617872
resolver
genesymbol
MICOS10
resolver
genesymbol_syn
C1orf151
resolver
genesymbol_syn
MIC10
resolver
genesymbol_syn
MINOS1
resolver
hgnc
HGNC:32068
resolver
uniprot
A0A087WU07
resolver
uniprot
Q96G68
resolver
uniprot_entry
A0A087WU07_HUMAN
resolver
uniprot_entry
MIC10_HUMAN
resolver
uniprot_sec
Q96G68
resolver
amino_acid_sequence
MSESELGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAPYLLHGKYVKEQEQ
uniprot
proteins
function
FUNCTION: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. {ECO:0000269|PubMed:22114354, ECO:0000269|PubMed:32567732, ECO:0000269|PubMed:33130824}.
uniprot
proteins
mass_dalton
8808
uniprot
proteins
protein_family
MICOS complex subunit Mic10 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
22114354
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
24687277
uniprot
proteins
pubmed
25764979
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
25997101
uniprot
proteins
pubmed
31644573
uniprot
proteins
pubmed
32567732
uniprot
proteins
pubmed
33130824
uniprot
proteins
sequence_length
78
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:22114354}; Single-pass membrane protein {ECO:0000269|PubMed:22114354}. Note=The C-terminus is located in the intermembrane space (By similarity), while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (PubMed:22114354). {ECO:0000250, ECO:0000269|PubMed:22114354}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..36; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins