TEDC1
entrez
283643
canonical
uniprot
Q86SX3
canonical
ensembl
ENSG00000185347
resolver
ensp
ENSP00000333010
resolver
ensp
ENSP00000346568
resolver
ensp
ENSP00000376307
resolver
ensp
ENSP00000376308
resolver
ensp
ENSP00000376312
resolver
genesymbol
TEDC1
resolver
genesymbol_syn
C14orf80
resolver
hgnc
HGNC:20127
resolver
uniprot
B5MDG3
resolver
uniprot
E9PAQ4
resolver
uniprot
Q86TT3
resolver
uniprot
Q86TT4
resolver
uniprot
Q86TT5
resolver
uniprot
Q96B41
resolver
uniprot
Q9H7H4
resolver
uniprot_entry
TEDC1_HUMAN
resolver
uniprot_sec
B5MDG3
resolver
uniprot_sec
E9PAQ4
resolver
uniprot_sec
Q86TT3
resolver
uniprot_sec
Q86TT4
resolver
uniprot_sec
Q86TT5
resolver
uniprot_sec
Q96B41
resolver
uniprot_sec
Q9H7H4
resolver
amino_acid_sequence
MGRRRQRVDPAAGARAGALPEAIAALSRSLPSGPSPEIFRRAKFDRPEATSALWQLLFRVLSPLPAGNALASLALEVQARLVKSALCSQGYPRLALAQLPEDGSQGSRELLLALSWLLARGPVPEQMLAQARVPLGDEMTVCQCEALASPGPPAPHMEAEGPVDVRHVQWLMGKLRFRWRQLVSSQQEQCALLSKIHLYTRGCHSDQSLSHLSVTEAEMLRDPEGGQQVSGAGAAQNLDLAYPKCLHSFCTPGMGPRTFWNDLWLVCEQPGLLPGDWAAPLDPGGASACSLLSPFRALLRTLERENQRLEAVLAWRRSELVFWRWMDTVLGTCAPEVPAAASQPTFLPWVPERGGGELDLVVRELQALEEELREAAERRRAAWEAKAGGCGRGPEWSAARRASREAVEKELGALQQCWERDGGPAQPHGPHRLVRREDGAAGDRDLRAAVVIRTLRSQEACLEAVLRRLQGQCRQELARLVGARPGLIWIPPPGR
uniprot
proteins
function
FUNCTION: Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability (By similarity). May play a role in counteracting perturbation of actin filaments, such as after treatment with the actin depolymerizing microbial metabolite Chivosazole F (PubMed:28796488). {ECO:0000250|UniProtKB:Q3UK37, ECO:0000269|PubMed:28796488}.
uniprot
proteins
mass_dalton
54231
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
28796488
uniprot
proteins
pubmed
38252227
uniprot
proteins
sequence_length
495
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000250|UniProtKB:Q3UK37}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q3UK37}.
uniprot
proteins