Tm6sf2
entrez
107770
canonical
uniprot
Q8R1J1
canonical
ensembl
ENSMUSG00000036151
resolver
ensp
ENSMUSP00000046114
resolver
ensp
ENSMUSP00000105788
resolver
enst
ENSMUST00000049197
resolver
enst
ENSMUST00000110160
resolver
genesymbol
Tm6sf2
resolver
uniprot
A0A0R4J0J9
resolver
uniprot
E9QM19
resolver
uniprot
Q8BIG1
resolver
uniprot_entry
A0A0R4J0J9_MOUSE
resolver
uniprot_entry
E9QM19_MOUSE
resolver
uniprot_entry
TM6S2_MOUSE
resolver
uniprot_sec
Q8BIG1
resolver
amino_acid_sequence
MDIPPLAGRTVAMSFCALPVSYLLNQVSAFSQPLFVVLTSALILGLLFLAVYSLSHGEITYDPLYAVFVIFSFTSVVDLVIALQEDGYMMGFMDFYTKEGEPYLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSILVFLPGNILGKYSSEMRPTFFLAILYMLVPCWAGVRIFNQSRAPTSYTPDMVQEEQKKSLLQRPADLALIVYLIFAALFTVFRGLVVLDCPTDACFIYIYQYEPYLRDPVAYPKLQMLMYLFYALPFYCLAAYALAFPGCSWLPDWALVFAGAIGQAQFSHMGASMHMRTPFTYRVPEDTWATFFLSNLLLALGPHLLAFRCLWRPAFFLHAALPSSPQDQDKKQQ
uniprot
proteins
function
FUNCTION: Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase. {ECO:0000250|UniProtKB:Q9BZW4, ECO:0000269|PubMed:24531328, ECO:0000269|PubMed:24633158}.
uniprot
proteins
mass_dalton
43027
uniprot
proteins
protein_family
TM6SF family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
24531328
uniprot
proteins
pubmed
24633158
uniprot
proteins
sequence_length
378
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9BZW4}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q9BZW4}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 10..30; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 34..54; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 63..83; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 110..130; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 140..160; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 170..190; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 219..239; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 269..289; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 291..311; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 332..352; /note="Helical; Name=10"; /evidence="ECO:0000255
uniprot
proteins