As3mt
entrez
140925
canonical
uniprot
Q8VHT6
canonical
ensembl
ENSRNOG00000020081
resolver
ensembl
ENSRNOG00060029581
resolver
ensp
ENSRNOP00000027223
resolver
ensp
ENSRNOP00060042789
resolver
enst
ENSRNOT00000027223
resolver
enst
ENSRNOT00060051439
resolver
genesymbol
As3mt
resolver
genesymbol_syn
Cyt19
resolver
uniprot
G3V8P2
resolver
uniprot_entry
AS3MT_RAT
resolver
uniprot_entry
G3V8P2_RAT
resolver
amino_acid_sequence
MAAPRDAEIHKDVQNYYGNVLKTSADLQTNACVTPAKGVPEYIRKSLQNVHEEVISRYYGCGLVVPEHLENCRILDLGSGSGRDCYVLSQLVGQKGHITGIDMTKVQVEVAKAYLEYHTEKFGFQTPNVTFLHGQIEMLAEAGIQKESYDIVISNCVINLVPDKQKVLREVYQVLKYGGELYFSDVYASLEVSEDIKSHKVLWGECLGGALYWKDLAVIAKKIGFCPPRLVTANIITVGNKELERVLGDCRFVSATFRLFKLPKTEPAGRCQVVYNGGIMGHEKELIFDANFTFKEGEAVEVDEETAAILRNSRFAHDFLFTPVEASLLAPQTKVIIRDPFKLAEESDKMKPRCAPEGTGGCCGKRKSC
uniprot
proteins
ec_number
2.1.1.137
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH. {ECO:0000269|PubMed:11790780}.
uniprot
proteins
mass_dalton
41056
uniprot
proteins
mutagenesis
MUTAGEN 156; /note="C->S: Complete loss of activity."; /evidence="ECO:0000269|PubMed:15808521
uniprot
proteins
protein_family
Arsenite methyltransferase family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
11790780
uniprot
proteins
pubmed
15808521
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
369
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:11790780}.
uniprot
proteins