Prodh2
entrez
56189
canonical
uniprot
Q8VCZ9
canonical
ensembl
ENSMUSG00000036892
resolver
ensp
ENSMUSP00000062214
resolver
ensp
ENSMUSP00000273499
resolver
ensp
ENSMUSP00000273504
resolver
enst
ENSMUST00000058280
resolver
genesymbol
Prodh2
resolver
genesymbol_syn
Hypdh
resolver
uniprot
Q2V058
resolver
uniprot
Q9QX62
resolver
uniprot_entry
HYPDH_MOUSE
resolver
uniprot_sec
Q2V058
resolver
uniprot_sec
Q9QX62
resolver
amino_acid_sequence
MIWTRLPLYGPSKPSTGGWQPLRFDGGAFHVKGTAELARALLVLRLCAWPPLVTHGLAFQAWSQRLLGSRLSGALLRASIYGQFVAGETAEEVRNCVGQLQALGLQPLLAVPTEEEPDSTAKTSEVWYEENLSAMLRCVDLSRALVDAHGPARNSLMQLKVTALASTRLCKELSAWIQRPRGSSELSPERLAEAMDSGRNLQLSCLSTEQNQHLQASLSRLHRVAQHARAKCVRLLVDAEYTFINPALSLLVAALAVRWNSPEEGGPWVWNTYQAYLKDTHQRLEQDAEAAHKAGLAFGVKLVRGAYLDKERSMTQLQGKEDCTQPDYEATSRSYSRCLELMLRCVSNHGPPCHLMVASHNEESVRQATKRMWELGIPLDGPVCFGQLLGMCDHVSLALGQAGYMVYKSIPYGCLEEVIPYLIRRAQENRSVLQGARREQALLSQELWRRLLGRTA
uniprot
proteins
ec_number
1.5.5.2
uniprot
proteins
ec_number
1.5.5.3
uniprot
proteins
function
FUNCTION: Dehydrogenase that converts trans-4-L-hydroxyproline to delta-1-pyrroline-3-hydroxy-5-carboxylate (Hyp) using ubiquinone-10 as the terminal electron acceptor. Can also use proline as a substrate but with a very much lower efficiency. Does not react with other diastereomers of Hyp: trans-4-D-hydroxyproline and cis-4-L-hydroxyproline. Ubiquininone analogs such as menadione, duroquinone and ubiquinone-1 react more efficiently than oxygen as the terminal electron acceptor during catalysis. {ECO:0000250|UniProtKB:Q9UF12}.
uniprot
proteins
mass_dalton
50723
uniprot
proteins
protein_family
Proline oxidase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15581617
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
sequence_length
456
uniprot
proteins