Cd207
entrez
246278
canonical
uniprot
Q8VBX4
canonical
ensembl
ENSMUSG00000034783
resolver
ensp
ENSMUSP00000040746
resolver
enst
ENSMUST00000037882
resolver
genesymbol
Cd207
resolver
genesymbol_syn
Clec4k
resolver
uniprot
Q8R442
resolver
uniprot_entry
CLC4K_MOUSE
resolver
uniprot_sec
Q8R442
resolver
amino_acid_sequence
MPEAEMKEEAPEAHFTVDKQNISLWPREPPPKQDLSPVLRKPLCICVAFTCLALVLVTSIVLQAVFYPRLMGKILDVKSDAQMLKGRVDNISTLGSDLKTERGRVDDAEVQMQIVNTTLKRVRSQILSLETSMKIANDQLQILTMSWGEVDSLSAKIPELKRDLDKASALNTKVQGLQNSLENVNKLLKQQSDILEMVARGWKYFSGNFYYFSRTPKTWYSAEQFCISRKAHLTSVSSESEQKFLYKAADGIPHWIGLTKAGSEGDWYWVDQTSFNKEQSRRFWIPGEPNNAGNNEHCANIRVSALKCWNDGPCDNTFLFICKRPYVQTTE
uniprot
proteins
function
FUNCTION: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. {ECO:0000269|PubMed:11777972, ECO:0000269|PubMed:18322168}.
uniprot
proteins
mass_dalton
37621
uniprot
proteins
pubmed
11777972
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18322168
uniprot
proteins
sequence_length
331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. Note=Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 42..62; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins