Tdrd7
entrez
100121
canonical
uniprot
Q8K1H1
canonical
ensembl
ENSMUSG00000035517
resolver
ensp
ENSMUSP00000099993
resolver
ensp
ENSMUSP00000103406
resolver
ensp
ENSMUSP00000290871
resolver
ensp
ENSMUSP00000290881
resolver
ensp
ENSMUSP00000290886
resolver
ensp
ENSMUSP00000290891
resolver
enst
ENSMUST00000102929
resolver
enst
ENSMUST00000107777
resolver
genesymbol
Tdrd7
resolver
genesymbol_syn
Pctaire2bp
resolver
uniprot
A0A0A0MQD1
resolver
uniprot
B1AWG7
resolver
uniprot
B1AWH5
resolver
uniprot
Q8R181
resolver
uniprot_entry
A0A0A0MQD1_MOUSE
resolver
uniprot_entry
TDRD7_MOUSE
resolver
uniprot_sec
B1AWG7
resolver
uniprot_sec
B1AWH5
resolver
uniprot_sec
Q8R181
resolver
amino_acid_sequence
MLEADLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVVRIEASRSGEIVCYAVACTETARIAQLVARQRTSKRKIGRQINCQMRVKKAMPFFLEGKPKATLRQPGFASDYSISRKPNSALLRDRGSALGVKADVDMPPYPDTPVQRHASMSANSRFSPKSSLPASFQTHISRACPTEVNDNLNQTVEKPNITPPASYTNKMDEVQNRIKEILDKHNNGIWISKLPHFYKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGGQDSLLYPARREQPLKSDQDPEKELPPPPPAPKQEVPSQGSPAVMPDVKEKVAELLGKYSSGLWASALPKAFEDMYKVKFPEDALKNLASLSDVCTINYISGNTQKAILYAKLPLPTDKILKDEGQAQGDFDIKSMIEQEYLQIEKNMAESADEFLEDITVPPLVIPTEASPSVLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEFYSKNPRVTPIQTVHVGQLLAVNAEEDAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSFQATKCKLAGLEVLNDDPDLVKAVESLTCGKIFAVEILDKSDVPLVVLYDTSGEDDININATCLKAICDRSLQVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKMDETKGVAYVYLFTPNNFPDPHRSINRQITNADLWKHQKDVFLSAVSTAASSPGNRNGGTPAPGSPAESLRKSHPEVIKKSVLDHTSSFSLEELPPPVHLSRSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVERDQVYAAKVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDVFRKLPFQAVTAQLAGVKCSQWSEEASMVFRNHVEKKALVALVQTVVEHTNPWDRKVVLYLVDTSLPDTDTWIHDFMSQYLLELSKVN
uniprot
proteins
function
FUNCTION: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis. {ECO:0000269|PubMed:21436445}.
uniprot
proteins
mass_dalton
122174
uniprot
proteins
protein_family
TDRD7 family
uniprot
proteins
pubmed
11527406
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17141210
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19584108
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21436445
uniprot
proteins
sequence_length
1086
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11527406, ECO:0000269|PubMed:17141210, ECO:0000269|PubMed:21436445}. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids.
uniprot
proteins