TFAP2D
entrez
83741
canonical
uniprot
Q7Z6R9
canonical
ensembl
ENSG00000008197
resolver
ensp
ENSP00000008391
resolver
enst
ENST00000008391
resolver
genesymbol
TFAP2D
resolver
genesymbol_syn
TFAP2BL1
resolver
hgnc
HGNC:15581
resolver
uniprot
Q8IWX0
resolver
uniprot_entry
AP2D_HUMAN
resolver
uniprot_sec
Q8IWX0
resolver
amino_acid_sequence
MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGLVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKTSEAAVKEGKTEKTD
uniprot
proteins
function
FUNCTION: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
49578
uniprot
proteins
protein_family
AP-2 family
uniprot
proteins
pubmed
11733187
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
16959974
uniprot
proteins
sequence_length
452
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins