Gfra2
entrez
14586
canonical
uniprot
O08842
canonical
ensembl
ENSMUSG00000022103
resolver
ensp
ENSMUSP00000022699
resolver
ensp
ENSMUSP00000154391
resolver
genesymbol
Gfra2
resolver
genesymbol_syn
Gdnfrb
resolver
genesymbol_syn
Trnr2
resolver
uniprot
Q3UET6
resolver
uniprot
Q3UUD8
resolver
uniprot
Q920Y3
resolver
uniprot
Q9Z2A2
resolver
uniprot
Q9Z2A3
resolver
uniprot_entry
GFRA2_MOUSE
resolver
uniprot_entry
Q3UET6_MOUSE
resolver
uniprot_sec
Q3UUD8
resolver
uniprot_sec
Q920Y3
resolver
uniprot_sec
Q9Z2A2
resolver
uniprot_sec
Q9Z2A3
resolver
amino_acid_sequence
MILANAFCLFFFLDETLRSLASPSSPQGSELHGWRPQVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRSLCRTDHLCRSRLADFHANCRASYRTITSCPADNYQACLGSYAGMIGFDMTPNYVDSNPTGIVVSPWCNCRGSGNMEEECEKFLKDFTENPCLRNAIQAFGNGTDVNMSPKGPTFSATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSIQEQGLKANNSKELSMCFTELTTNISPGSKKVIKLYSGSCRARLSTALTALPLLMVTLAQ
uniprot
proteins
function
FUNCTION: Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons (PubMed:9182803). NRTN-binding leads to autophosphorylation and activation of the RET receptor (PubMed:9182803). Also able to mediate GDNF signaling through the RET tyrosine kinase receptor (By similarity). {ECO:0000250|UniProtKB:O00451, ECO:0000269|PubMed:9182803}.; FUNCTION: [Isoform 2]: Participates in NRTN-induced 'Ser-727' phosphorylation of STAT3. {ECO:0000269|PubMed:23872421}.
uniprot
proteins
mass_dalton
51727
uniprot
proteins
protein_family
GDNFR family
uniprot
proteins
pubmed
12829325
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23872421
uniprot
proteins
pubmed
9182803
uniprot
proteins
pubmed
9875703
uniprot
proteins
sequence_length
464
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:9182803}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:9182803}.
uniprot
proteins