DENND6B
entrez
414918
canonical
uniprot
Q8NEG7
canonical
ensembl
ENSG00000205593
resolver
ensp
ENSP00000391524
resolver
ensp
ENSP00000543028
resolver
ensp
ENSP00000543030
resolver
ensp
ENSP00000612450
resolver
ensp
ENSP00000705475
resolver
ensp
ENSP00000705476
resolver
enst
ENST00000413817
resolver
genesymbol
DENND6B
resolver
genesymbol_syn
FAM116B
resolver
hgnc
HGNC:32690
resolver
uniprot
A6X8I5
resolver
uniprot_entry
DEN6B_HUMAN
resolver
uniprot_sec
A6X8I5
resolver
amino_acid_sequence
MDALLGTGPRRARGCLGAAGPTSSGRAARTPAAPWARFSAWLECVCVVTFDLELGQALELVYPNDFRLTDKEKSSICYLSFPDSHSGCLGDTQFSFRMRQCGGQRSPWHADDRHYNSRAPVALQREPAHYFGYVYFRQVKDSSVKRGYFQKSLVLVSRLPFVRLFQALLSLIAPEYFDKLAPCLEAVCSEIDQWPAPAPGQTLNLPVMGVVVQVRIPSRVDKSESSPPKQFDQENLLPAPVVLASVHELDLFRCFRPVLTHMQTLWELMLLGEPLLVLAPSPDVSSEMVLALTSCLQPLRFCCDFRPYFTIHDSEFKEFTTRTQAPPNVVLGVTNPFFIKTLQHWPHILRVGEPKMSGDLPKQVKLKKPSRLKTLDTKPGLYTAYTAHLHRDKALLKRLLKGVQKKRPSDVQSALLRRHLLELTQSFIIPLEHYMASLMPLQKSITPWKTPPQIQPFSQDDFLRSLEHAGPQLTCILKGDWLGLYRRFFKSPHFDGWYRQRHKEMALKLEALHLEAICEANIETWMKDKSEVEVVDLVLKLREKLVRAQGHQLPVKEATLQRAQLYIETVIGSLPKDLQAVLCPP
uniprot
proteins
function
FUNCTION: Guanine nucleotide exchange factor (GEF) for RAB14. Also has some, lesser GEF activity towards RAB35. {ECO:0000269|PubMed:22595670}.
uniprot
proteins
mass_dalton
66464
uniprot
proteins
protein_family
DENND6 family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21330364
uniprot
proteins
pubmed
22595670
uniprot
proteins
sequence_length
585
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Recycling endosome {ECO:0000305}. Cytoplasm {ECO:0000305}.
uniprot
proteins