Farp1
entrez
306183
canonical
uniprot
F1LYQ8
canonical
ensembl
ENSRNOG00000011203
resolver
ensembl
ENSRNOG00055002999
resolver
ensembl
ENSRNOG00060008354
resolver
ensembl
ENSRNOG00065007529
resolver
ensp
ENSRNOP00000015271
resolver
ensp
ENSRNOP00055003444
resolver
ensp
ENSRNOP00060010618
resolver
ensp
ENSRNOP00065008628
resolver
enst
ENSRNOT00000015271
resolver
enst
ENSRNOT00055004670
resolver
enst
ENSRNOT00060013907
resolver
enst
ENSRNOT00065011793
resolver
genesymbol
Farp1
resolver
uniprot_entry
FARP1_RAT
resolver
amino_acid_sequence
MGEIEQKPTPASRLGAPENSGISTLERGQKPPPTPSGKLMTVKIQMLDDTQEAFEVPQRAPGKVLFDAVCNHLNLVEGDYFGLEFPDHRKIVVWLDLLKPIVKQIRRPKHVLVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALDREHLAKNKYVPQQDALEDKIVEFHHSHIGQTPAESDFQLLEVARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLMAGRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGHKKVQFERKHSKIHSTRSLVSQPTAPNSEVPKQSPQSASLTFGEGTESPSAQSCQQAKETKVCTLEPGPRQSPALSKSPSGSKAADGTAAAAPPEEEDEEEGGKDGIRPSNPQPPQPSTGSLTGSPHLSELSINSQGGAAPANVTLSPNLSPDNKQASPLISPLLNDQACPRTDDEEEGRRKRFPTDKAYYIAKEVSTTERTYLKDLEVIASWFQSTVSKEDSMPEALKSLIFPNFEPLHKFHTNFLKEIEQRLALWEGRSNAHIRGDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALETSIKGSRRLEHFCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPNHADFRDCRAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVIPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEEEWGVPHCLTLRGQRQSIIVAASSRSEMEKWLEDIQMAIDLAEKSNGPTPELLASSPPDNKSPDEATAADQESEDDLSASRTSLERQAPHRGNTMVHVCWHRSTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSHQDSHPLASLPLLGYSLTIPSESENIHKDYVFKLHFKSHVYYFRAESEYTFERWMEVIRSATSSASRAHSLSHKESHLY
uniprot
proteins
function
FUNCTION: May play a role in semaphorin signaling (By similarity). Functions as a guanine nucleotide exchange factor for RAC1. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses. {ECO:0000250, ECO:0000269|PubMed:23209303}.
uniprot
proteins
mass_dalton
118842
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
23209303
uniprot
proteins
sequence_length
1049
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23209303}; Peripheral membrane protein {ECO:0000269|PubMed:23209303}; Cytoplasmic side {ECO:0000269|PubMed:23209303}. Synapse {ECO:0000250}. Synapse, synaptosome {ECO:0000269|PubMed:23209303}. Cytoplasm, cytosol {ECO:0000269|PubMed:23209303}. Cell projection, filopodium {ECO:0000269|PubMed:23209303}. Cell projection, dendrite {ECO:0000269|PubMed:23209303}. Cell projection, dendritic spine {ECO:0000269|PubMed:23209303}. Note=Recruited to the cell membrane via interaction with CADM1.
uniprot
proteins