RSRP1
entrez
57035
canonical
uniprot
Q9BUV0
canonical
ensembl
ENSG00000117616
resolver
ensp
ENSP00000243189
resolver
ensp
ENSP00000549859
resolver
genesymbol
RSRP1
resolver
genesymbol_syn
C1orf63
resolver
hgnc
HGNC:25234
resolver
uniprot
A8K917
resolver
uniprot
Q49AA4
resolver
uniprot
Q5TH71
resolver
uniprot
Q9GZP6
resolver
uniprot_entry
RSRP1_HUMAN
resolver
uniprot_sec
A8K917
resolver
uniprot_sec
Q49AA4
resolver
uniprot_sec
Q5TH71
resolver
uniprot_sec
Q9GZP6
resolver
amino_acid_sequence
MSNYVNDMWPGSPQEKDSPSTSRSGGSSRLSSRSRSRSFSRSSRSHSRVSSRFSSRSRRSKSRSRSRRRHQRKYRRYSRSYSRSRSRSRSRRYRERRYGFTRRYYRSPSRYRSRSRSRSRSRGRSYCGRAYAIARGQRYYGFGRTVYPEEHSRWRDRSRTRSRSRTPFRLSEKDRMELLEIAKTNAAKALGTTNIDLPASLRTVPSAKETSRGIGVSSNGAKPELSEKVTEDGTRNPNEKPTQQRSIAFSSNNSVAKPIQKSAKAATEEASSRSPKIDQKKSPYGLWIPI
uniprot
proteins
function
FUNCTION: Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6. {ECO:0000269|PubMed:34042961}.
uniprot
proteins
mass_dalton
33613
uniprot
proteins
mutagenesis
MUTAGEN 107..109; /note="SPS->APA: Reduces interaction with spliceosome factors."; /evidence="ECO:0000269|PubMed:34042961"; MUTAGEN 107; /note="S->A: No effect on interaction with spliceosome factors."; /evidence="ECO:0000269|PubMed:34042961"; MUTAGEN 109; /note="S->A: No effect on interaction with spliceosome factors."; /evidence="ECO:0000269|PubMed:34042961
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. Phosphorylation at Ser-107 and Ser-109 mediates the interaction with spliceosome proteins. {ECO:0000269|PubMed:34042961}.
uniprot
proteins
protein_family
RSRP family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
34042961
uniprot
proteins
sequence_length
290
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:34042961}.
uniprot
proteins