Fbxw19
entrez
235612
canonical
uniprot
Q8C2W8
canonical
ensembl
ENSMUSG00000074061
resolver
ensp
ENSMUSP00000075918
resolver
enst
ENSMUST00000076617
resolver
genesymbol
Fbxw19
resolver
uniprot
K9J6X5
resolver
uniprot_entry
K9J6X5_MOUSE
resolver
uniprot_entry
Q8C2W8_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: In oocytes and preimplantation embryos, SCF(Fbxw19) ubiquitin ligase complex is maintained inactive by cytoplasmic lattices. {ECO:0000269|PubMed:41917274}.
uniprot
proteins
amino_acid_sequence
MEIHLPSLPMMKILSYLDAYSLLQAAKVNKNWNELASSDVLWRKLCQKRWLYCDRVTLQLHGLETWKQFFISRTWQEHAKTRAKPEDFNYKEIPVAFEFRAHPCYISRHGLIRNGQGKSAVCMVTSTNRISTWDVHEGAMTWVSPVQPSYITRMTTLPEMHIAVTIDMQSNIKLWDCHNRKVLATTGLLSSCQLLQAVFTNDSPIVLVGDILGNLYIFRIPDLHLISKVNVFPYGIDELHCSPQKKWVLLIGKQRHVLTKVFYMSSLLRTSEFSAPVSTDLKFSLCQRAFWTPRREDRITLMSSTIPPDPTKFATFDMKLEEIENKVTIQGHLVASFSLQDCKERAEWMGVSDKDVIVCSTGSSLLLFDINGLRLQTFQYCPEEILRLCVDPVHVIVTCNNGSLDVYVWEERSPLLRRCYRLRKRGYLPLSGFIIKTLCDESSIILVMTSSPIPCFLMAYTLKVCS
uniprot
proteins
function
FUNCTION: Substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, which mediates ubiquitination and degradation of target proteins. {ECO:0000250|UniProtKB:E9PXM9}.
uniprot
proteins
mass_dalton
53592
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:E9PXM9}.
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
41917274
uniprot
proteins
sequence_length
466
uniprot
proteins