Rbm38
entrez
56190
canonical
uniprot
Q62176
canonical
ensembl
ENSMUSG00000027510
resolver
ensp
ENSMUSP00000029014
resolver
ensp
ENSMUSP00000133816
resolver
enst
ENSMUST00000029014
resolver
enst
ENSMUST00000173393
resolver
genesymbol
Rbm38
resolver
genesymbol_syn
Rnpc1
resolver
genesymbol_syn
Seb4
resolver
genesymbol_syn
Seb4l
resolver
uniprot
Q5U418
resolver
uniprot
Q922Z2
resolver
uniprot_entry
RBM38_MOUSE
resolver
uniprot_sec
Q5U418
resolver
uniprot_sec
Q922Z2
resolver
amino_acid_sequence
MLLQPACSPSVFPRPSAAPSAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAADRACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAVGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPATPVPSLSSPYLEYTPASPAYAQYPPATYDQYPYAASPAAATSFVGYGYPAAVPQALSAAAPAGTTFVQYQAPQLQPDRMQ
uniprot
proteins
function
FUNCTION: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2 (By similarity). Plays a role in myogenic differentiation. {ECO:0000250, ECO:0000269|PubMed:19817877}.
uniprot
proteins
mass_dalton
25364
uniprot
proteins
protein_family
RBM38 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19817877
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
237
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins