NIPSNAP2
entrez
2631
canonical
uniprot
O75323
canonical
ensembl
ENSG00000146729
resolver
ensp
ENSP00000313050
resolver
ensp
ENSP00000406855
resolver
genesymbol
NIPSNAP2
resolver
genesymbol_syn
GBAS
resolver
hgnc
HGNC:4179
resolver
uniprot
C9IYJ3
resolver
uniprot
O43801
resolver
uniprot
Q53X96
resolver
uniprot_entry
NIPS2_HUMAN
resolver
uniprot_sec
C9IYJ3
resolver
uniprot_sec
O43801
resolver
uniprot_sec
Q53X96
resolver
amino_acid_sequence
MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
uniprot
proteins
function
FUNCTION: Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria (PubMed:30982665). Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2) (PubMed:30982665). {ECO:0000269|PubMed:30982665}.
uniprot
proteins
mass_dalton
33743
uniprot
proteins
protein_family
NipSnap family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26387735
uniprot
proteins
pubmed
30982665
uniprot
proteins
pubmed
9615231
uniprot
proteins
pubmed
9661659
uniprot
proteins
sequence_length
286
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:30982665}.
uniprot
proteins