AFAP1L2
entrez
84632
canonical
uniprot
Q8N4X5
canonical
ensembl
ENSG00000169129
resolver
ensp
ENSP00000303042
resolver
ensp
ENSP00000358276
resolver
ensp
ENSP00000512810
resolver
ensp
ENSP00000524019
resolver
ensp
ENSP00000524020
resolver
ensp
ENSP00000524022
resolver
ensp
ENSP00000524023
resolver
ensp
ENSP00000524026
resolver
ensp
ENSP00000594870
resolver
ensp
ENSP00000611539
resolver
enst
ENST00000696688
resolver
genesymbol
AFAP1L2
resolver
genesymbol_syn
KIAA1914
resolver
genesymbol_syn
XB130
resolver
hgnc
HGNC:25901
resolver
uniprot
A0A8Q3SIY9
resolver
uniprot
A8K6P7
resolver
uniprot
B3KVQ8
resolver
uniprot
B7Z2Q0
resolver
uniprot
Q2UZW3
resolver
uniprot
Q8TB54
resolver
uniprot
Q96PX4
resolver
uniprot
Q96SY5
resolver
uniprot_entry
A0A8Q3SIY9_HUMAN
resolver
uniprot_entry
AF1L2_HUMAN
resolver
uniprot_entry
B7Z2Q0_HUMAN
resolver
uniprot_sec
A8K6P7
resolver
uniprot_sec
B3KVQ8
resolver
uniprot_sec
Q2UZW3
resolver
uniprot_sec
Q8TB54
resolver
uniprot_sec
Q96PX4
resolver
uniprot_sec
Q96SY5
resolver
amino_acid_sequence
MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKVTINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESPEGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPDCTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS
uniprot
proteins
function
FUNCTION: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. {ECO:0000269|PubMed:17412687}.
uniprot
proteins
mass_dalton
91300
uniprot
proteins
mutagenesis
MUTAGEN 4; /note="Y->F: Reduced interaction with SRC."; /evidence="ECO:0000269|PubMed:17412687
uniprot
proteins
post_translational_modification
PTM: Tyrosine phosphorylated (by SRC). {ECO:0000269|PubMed:17412687, ECO:0000269|PubMed:18844995}.
uniprot
proteins
pubmed
11572484
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17412687
uniprot
proteins
pubmed
18844995
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
818
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17412687}.
uniprot
proteins