P83645
uniprot
P83645
canonical
amino_acid_sequence
MAYIAKSFYDLSAIGLDGEKIDFNTFRGRAVLIENVASLUGTTTRDYTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRHGGGFQPTFSLTQKCDVNGQNQHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVSWNFEKFLIGPEGEPFRRYSRTFQTINIEPDIKRLLKVAI
uniprot
proteins
ec_number
1.11.1.12
uniprot
proteins
ec_number
1.11.1.9
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis (PubMed:9685647). Can reduce small soluble hydroperoxide such as H2O2 (PubMed:9685647). Can reduce cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide (By similarity). {ECO:0000250|UniProtKB:P18283, ECO:0000269|PubMed:9685647}.
uniprot
proteins
mass_dalton
22014
uniprot
proteins
protein_family
Glutathione peroxidase family
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8889548
uniprot
proteins
pubmed
9685647
uniprot
proteins
sequence_length
190
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P18283}.
uniprot
proteins