MBIP
entrez
51562
canonical
uniprot
Q9NS73
canonical
ensembl
ENSG00000151332
resolver
ensp
ENSP00000324444
resolver
ensp
ENSP00000352517
resolver
ensp
ENSP00000399718
resolver
ensp
ENSP00000575255
resolver
ensp
ENSP00000575257
resolver
ensp
ENSP00000675456
resolver
genesymbol
MBIP
resolver
hgnc
HGNC:20427
resolver
uniprot
B2RCV0
resolver
uniprot
Q86TZ2
resolver
uniprot
Q96AS5
resolver
uniprot
Q9BS93
resolver
uniprot
Q9NZE1
resolver
uniprot_entry
B2RCV0_HUMAN
resolver
uniprot_entry
MBIP1_HUMAN
resolver
uniprot_sec
Q86TZ2
resolver
uniprot_sec
Q96AS5
resolver
uniprot_sec
Q9BS93
resolver
uniprot_sec
Q9NZE1
resolver
amino_acid_sequence
MAAATELNRPSSGDRNLERRCRPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKLQSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFSIGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVREFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSMLRDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSGKRRKVQPPQQNYSLAELDEKISALKQALLRKSREAESMATHHLP
uniprot
proteins
function
FUNCTION: Functions as part of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (PubMed:19103755). Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway (PubMed:10801814). Together with MOCS2B, inhibits the activity of stress kinase EIF2AK2/PKR; this may lead to effects such as suppression of JNK activation and subsequent stress-responsive transcription, or suppression of eIF2a phosphorylation to favor translation (PubMed:26705305). {ECO:0000269|PubMed:10801814, ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:26705305}.
uniprot
proteins
mass_dalton
39281
uniprot
proteins
pubmed
10801814
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19103755
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
26705305
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
344
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10801814, ECO:0000269|PubMed:26705305}. Cytoplasm {ECO:0000269|PubMed:10801814, ECO:0000269|PubMed:26705305}. Note=Shows a cytoplasmic localization when coexpressed with MAP3K12. {ECO:0000269|PubMed:10801814}.
uniprot
proteins