Ldlrad3
entrez
241576
canonical
uniprot
A2AR95
canonical
ensembl
ENSMUSG00000048058
resolver
ensp
ENSMUSP00000054134
resolver
ensp
ENSMUSP00000106853
resolver
ensp
ENSMUSP00000213467
resolver
ensp
ENSMUSP00000213468
resolver
genesymbol
Ldlrad3
resolver
uniprot
A2AR96
resolver
uniprot
B2RR20
resolver
uniprot
B7ZND2
resolver
uniprot
Q8CCS0
resolver
uniprot
Q8CDR7
resolver
uniprot_entry
B2RR20_MOUSE
resolver
uniprot_entry
B7ZND2_MOUSE
resolver
uniprot_entry
LRAD3_MOUSE
resolver
uniprot_sec
A2AR96
resolver
uniprot_sec
Q8CCS0
resolver
uniprot_sec
Q8CDR7
resolver
amino_acid_sequence
MWLLGPLCLLLSSTAESQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCRNGLCIDKSFICDGQNNCQDNSDEESCESSLEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHHCNVTYNVNNGVQYVATQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSAYSASSQAASSLLSVEASSHNPEQPGSPEGSAEPRDSVPSQGTEEV
uniprot
proteins
function
FUNCTION: May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production (PubMed:21795536). May regulate ITCH and NEDD4 E3 ligase activity and degradation (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q86YD5, ECO:0000269|PubMed:21795536}.
uniprot
proteins
mass_dalton
37467
uniprot
proteins
protein_family
LDLR family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21795536
uniprot
proteins
sequence_length
345
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:21795536}; Single-pass type I membrane protein {ECO:0000269|PubMed:21795536}.
uniprot
proteins
transmembrane_region
TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins