Prpf6
entrez
68879
canonical
uniprot
Q91YR7
canonical
ensembl
ENSMUSG00000002455
resolver
ensp
ENSMUSP00000002529
resolver
genesymbol
Prpf6
resolver
uniprot
Q3ULJ7
resolver
uniprot
Q542P0
resolver
uniprot
Q8CIK9
resolver
uniprot
Q8R3M8
resolver
uniprot
Q99JN1
resolver
uniprot
Q9CSZ0
resolver
uniprot_entry
PRP6_MOUSE
resolver
uniprot_sec
Q3ULJ7
resolver
uniprot_sec
Q542P0
resolver
uniprot_sec
Q8CIK9
resolver
uniprot_sec
Q8R3M8
resolver
uniprot_sec
Q99JN1
resolver
uniprot_sec
Q9CSZ0
resolver
amino_acid_sequence
MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLTPVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDMRKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENNEYERARRLLAKARSSAPTARVFMKSVKLEWVLGNISAAQELCEEALRHYEDFPKLWMMKGQIEEQGELMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAVFLEARPQRKTKSVDALKKCEHDPHVLLAVAKLFWSERKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCENAEPRHGELWCAVSKDITNWQRKIGEILVLVAARIKNTF
uniprot
proteins
function
FUNCTION: Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. {ECO:0000250|UniProtKB:O94906}.
uniprot
proteins
mass_dalton
106722
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PRP4K during spliceosome assembly. {ECO:0000250|UniProtKB:O94906}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
941
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:O94906}. Nucleus speckle {ECO:0000250|UniProtKB:O94906}. Note=Localized in splicing speckles. {ECO:0000250|UniProtKB:O94906}.
uniprot
proteins