CALB2
entrez
794
canonical
uniprot
P22676
canonical
ensembl
ENSG00000172137
resolver
ensembl
ENSG00000282830
resolver
ensp
ENSP00000307508
resolver
ensp
ENSP00000340294
resolver
ensp
ENSP00000488916
resolver
ensp
ENSP00000489007
resolver
enst
ENST00000302628
resolver
enst
ENST00000349553
resolver
enst
ENST00000635154
resolver
enst
ENST00000635371
resolver
genesymbol
CALB2
resolver
genesymbol_syn
CAB29
resolver
hgnc
HGNC:1435
resolver
uniprot
A0A140VK08
resolver
uniprot
A6NER6
resolver
uniprot
A8K4Y1
resolver
uniprot
Q53HD2
resolver
uniprot
Q96BK4
resolver
uniprot_entry
A0A140VK08_HUMAN
resolver
uniprot_entry
A6NER6_HUMAN
resolver
uniprot_entry
CALB2_HUMAN
resolver
uniprot_sec
A8K4Y1
resolver
uniprot_sec
Q53HD2
resolver
uniprot_sec
Q96BK4
resolver
amino_acid_sequence
MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKMKEFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDRSGYIDEHELDALLKDLYEKNKKEMNIQQLTNYRKSVMSLAEAGKLYRKDLEIVLCSEPPM
uniprot
proteins
function
FUNCTION: Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways (PubMed:2001709). Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory (By similarity). During embryonic development, it facilitates neuronal differentiation and maturation (By similarity). {ECO:0000250|UniProtKB:P47728, ECO:0000250|UniProtKB:Q08331, ECO:0000269|PubMed:2001709}.
uniprot
proteins
mass_dalton
31540
uniprot
proteins
protein_family
Calbindin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14755000
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2001709
uniprot
proteins
pubmed
2618861
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Synapse {ECO:0000250|UniProtKB:Q08331}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q08331}. Note=Located in dendrioles, small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell. {ECO:0000250|UniProtKB:Q08331}.
uniprot
proteins