Thap1
entrez
306547
canonical
uniprot
Q5U208
canonical
ensembl
ENSRNOG00000056956
resolver
ensembl
ENSRNOG00055007586
resolver
ensembl
ENSRNOG00060012081
resolver
ensembl
ENSRNOG00065002729
resolver
ensp
ENSRNOP00000071777
resolver
ensp
ENSRNOP00055010095
resolver
ensp
ENSRNOP00060016149
resolver
ensp
ENSRNOP00065002589
resolver
enst
ENSRNOT00055012678
resolver
enst
ENSRNOT00060020502
resolver
enst
ENSRNOT00065003711
resolver
genesymbol
Thap1
resolver
uniprot_entry
THAP1_RAT
resolver
amino_acid_sequence
MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKQWEAAVRRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFLYIEPHEKKEELEPQEQLPSPSPPTSQVDAAVGLLMPPLQTPDNLSVFCDHNYTVEDTMHQRKRILHLEQQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQREKDDASERGYVILPNDYFEIVEVPA
uniprot
proteins
function
FUNCTION: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
24688
uniprot
proteins
protein_family
THAP1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
210
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250}. Nucleus, PML body {ECO:0000250}.
uniprot
proteins