Scg3
entrez
20255
canonical
uniprot
P47867
canonical
ensembl
ENSMUSG00000032181
resolver
ensp
ENSMUSP00000034699
resolver
ensp
ENSMUSP00000149561
resolver
genesymbol
Scg3
resolver
uniprot
Q3UTT1
resolver
uniprot
Q3UZT8
resolver
uniprot
Q8R1D7
resolver
uniprot_entry
SCG3_MOUSE
resolver
uniprot_sec
Q3UTT1
resolver
uniprot_sec
Q3UZT8
resolver
uniprot_sec
Q8R1D7
resolver
amino_acid_sequence
MGFLWTGSWILVLVLNSGPIQAFPKPEGSQDKSLHNRELSAERPLNEQIAEAEADKIKKAFPSESKPSESNYSSVDNLNLLRAITEKETVEKERQSIRSPPFDNQLNVEDADSTKNRKLIDEYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEALQKLISKEANNYEETLDKPTSRTENQDGKIPEKVTPVAAVQDGFTNRENDETVSNTLTLSNGLERRTNPHREDDFEELQYFPNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNTTDSKSKLFPAPPEKSQEETDSTKEEAAKMEKEYGSLKDSTKDDNSNLGGKTDEATGKTEAYLEAIRKNIEWLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL
uniprot
proteins
function
FUNCTION: Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:16219686). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (PubMed:12388744). May also play a role in angiogenesis (PubMed:28330905). Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (By similarity). {ECO:0000250|UniProtKB:Q8WXD2, ECO:0000269|PubMed:12388744, ECO:0000269|PubMed:16219686, ECO:0000269|PubMed:28330905}.
uniprot
proteins
mass_dalton
53326
uniprot
proteins
pubmed
12388744
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16219686
uniprot
proteins
pubmed
17200173
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28330905
uniprot
proteins
pubmed
7917832
uniprot
proteins
sequence_length
471
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:12388744, ECO:0000269|PubMed:16219686}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:P47868}; Peripheral membrane protein {ECO:0000250}. Secreted {ECO:0000269|PubMed:12388744}. Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. {ECO:0000250|UniProtKB:P47868}.
uniprot
proteins