Stk16
entrez
20872
canonical
uniprot
O88697
canonical
ensembl
ENSMUSG00000026201
resolver
ensp
ENSMUSP00000027401
resolver
ensp
ENSMUSP00000276835
resolver
ensp
ENSMUSP00000276836
resolver
ensp
ENSMUSP00000276837
resolver
ensp
ENSMUSP00000276838
resolver
ensp
ENSMUSP00000276853
resolver
enst
ENSMUST00000027401
resolver
genesymbol
Stk16
resolver
genesymbol_syn
Edpk
resolver
genesymbol_syn
Krct
resolver
genesymbol_syn
Mpsk1
resolver
genesymbol_syn
Pkl12
resolver
genesymbol_syn
Tsf1
resolver
uniprot
Q3UEG5
resolver
uniprot
Q8BSV9
resolver
uniprot
Q9JMJ0
resolver
uniprot
Q9JMJ1
resolver
uniprot
Q9QX00
resolver
uniprot_entry
Q8BSV9_MOUSE
resolver
uniprot_entry
STK16_MOUSE
resolver
uniprot_sec
Q3UEG5
resolver
uniprot_sec
Q9JMJ0
resolver
uniprot_sec
Q9JMJ1
resolver
uniprot_sec
Q9QX00
resolver
amino_acid_sequence
MGHALCVCSRGTVIIDNKRYLFVQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEEAQREAEMHRLFQHPNILRLMAYSLKERGAKHEAWLLLPFFKKGTLWNEIERLKDQGSFLTEDQILPLLLGISRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVEGSRQALALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNELSIPQSPRHSSALRQLLSSMMTVDPQQRPHIPVLLSQLEALQPPAPGQHTTQI
uniprot
proteins
ec_number
2.7.10.2
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates (By similarity). May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins. {ECO:0000250, ECO:0000269|PubMed:9878782}.
uniprot
proteins
mass_dalton
34382
uniprot
proteins
post_translational_modification
PTM: Mainly autophosphorylated on serine/threonine residues. Also autophosphorylated on Tyr-198 (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
10364453
uniprot
proteins
pubmed
10947953
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9712705
uniprot
proteins
pubmed
9817935
uniprot
proteins
pubmed
9878782
uniprot
proteins
sequence_length
305
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000269|PubMed:9712705}. Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Associates with Golgi and Golgi-derived vesicles.
uniprot
proteins