SLC38A7
entrez
55238
canonical
uniprot
Q9NVC3
canonical
ensembl
ENSG00000103042
resolver
ensp
ENSP00000219320
resolver
ensp
ENSP00000454325
resolver
ensp
ENSP00000454646
resolver
ensp
ENSP00000455119
resolver
ensp
ENSP00000604566
resolver
ensp
ENSP00000604568
resolver
ensp
ENSP00000643297
resolver
ensp
ENSP00000705297
resolver
ensp
ENSP00000705304
resolver
enst
ENST00000564100
resolver
genesymbol
SLC38A7
resolver
genesymbol_syn
SNAT7
resolver
hgnc
HGNC:25582
resolver
uniprot
H3BMC5
resolver
uniprot
Q53GJ9
resolver
uniprot
Q9H9I5
resolver
uniprot_entry
H3BMC5_HUMAN
resolver
uniprot_entry
S38A7_HUMAN
resolver
uniprot_sec
Q53GJ9
resolver
uniprot_sec
Q9H9I5
resolver
amino_acid_sequence
MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
uniprot
proteins
function
FUNCTION: Symporter that selectively cotransports sodium ions and amino acids, such as L-glutamine and L-asparagine from the lysosome into the cytoplasm and may participates in mTORC1 activation (PubMed:28416685, PubMed:35561222). The transport activity requires an acidic lysosomal lumen (PubMed:28416685). {ECO:0000269|PubMed:28416685, ECO:0000269|PubMed:35561222}.
uniprot
proteins
mass_dalton
49966
uniprot
proteins
protein_family
Amino acid/polyamine transporter 2 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28416685
uniprot
proteins
pubmed
35561222
uniprot
proteins
sequence_length
462
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000269|PubMed:28416685, ECO:0000269|PubMed:35561222}; Multi-pass membrane protein {ECO:0000255}. Cell projection, axon {ECO:0000250|UniProtKB:Q8BWH0}. Note=In neurons, located in soma. {ECO:0000250|UniProtKB:Q8BWH0}.
uniprot
proteins
transmembrane_region
TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 130..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 178..198; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 205..225; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 239..259; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 282..302; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 319..339; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 371..391; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 395..415; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 428..448; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins