Noa1
entrez
56412
canonical
uniprot
Q9JJG9
canonical
ensembl
ENSMUSG00000036285
resolver
ensp
ENSMUSP00000045948
resolver
ensp
ENSMUSP00000211998
resolver
ensp
ENSMUSP00000212007
resolver
enst
ENSMUST00000047860
resolver
genesymbol
Noa1
resolver
uniprot
Q3T996
resolver
uniprot
Q3U044
resolver
uniprot
Q99JU4
resolver
uniprot_entry
NOA1_MOUSE
resolver
uniprot_sec
Q3T996
resolver
uniprot_sec
Q3U044
resolver
uniprot_sec
Q99JU4
resolver
amino_acid_sequence
MLPARLACGLLCGLRRGPAPAAACYGPARWLLEGKCEVPIRQRASSLGRRVPPSSTATEDYAEGPDTEERFLFPEYVPERTPEEQVRELQELRELQQLQQEKERERLQQREERLQQKLRAGFRTLPVPEFPDASVPPSGIYCSGCGAELHCQHPGLPGYLPEEKFRDAAQAEGGPARTVCQRCWLLVHHGRALRLQVSRDQYLELVSAALRRPGPALVLYMVNLLDLPDALLPDLPKLVGPKQLIVLGNKVDLLPQDAPGYLKRLRKRLWDDCIRAGLVVAPGHQGPQYPAGDEPLEEIKNQNPSSRSRTVVKDVRLISAKTGYGVEEMISALQRSWRYRGDVYLVGTTNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRQRRLQEDATKAEEDLSEEEQSQLNQLKKHGYIVGRVGRTFSYSREQDEVPFEFDADSLAFDMGSEPVVSVCKSTKQIELTPEDVKDAHWFYDTPGITKESCILNLLTEKEINTVLPTHSIIPRTFVLKPGMVLFLGGIARIDFLQGNQSAWFTVVASNFLPVHITSLDKADALYEKHAGHELLLVPMGGKERMAQFPPLVAEDITLKGGGKFEAVADIKFSSAGWVAVTPYSEGTLHLRGHTPEGTALTVHPPVLPYIVNVKGQRMKKSVAYKTKKPPSLVHNLKKHR
uniprot
proteins
function
FUNCTION: Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP. {ECO:0000269|PubMed:18456285, ECO:0000269|PubMed:21118999}.
uniprot
proteins
mass_dalton
77379
uniprot
proteins
mutagenesis
MUTAGEN 353; /note="K->R: Loss of ability to regulate activity of mitochondrial respiratory chain complexes."; /evidence="ECO:0000269|PubMed:18456285
uniprot
proteins
protein_family
NOA1 subfamily
uniprot
proteins
protein_family
TRAFAC class YlqF/YawG GTPase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16380119
uniprot
proteins
pubmed
18456285
uniprot
proteins
pubmed
21118999
uniprot
proteins
sequence_length
693
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:16380119, ECO:0000269|PubMed:18456285}; Peripheral membrane protein {ECO:0000269|PubMed:16380119, ECO:0000269|PubMed:18456285}; Matrix side {ECO:0000269|PubMed:16380119, ECO:0000269|PubMed:18456285}.
uniprot
proteins