Acta2
entrez
81633
canonical
uniprot
P62738
canonical
ensembl
ENSRNOG00000058039
resolver
ensembl
ENSRNOG00055029988
resolver
ensembl
ENSRNOG00060028947
resolver
ensembl
ENSRNOG00065029660
resolver
ensp
ENSRNOP00000073101
resolver
ensp
ENSRNOP00055043094
resolver
ensp
ENSRNOP00060042272
resolver
ensp
ENSRNOP00065042414
resolver
enst
ENSRNOT00000083468
resolver
enst
ENSRNOT00055052159
resolver
enst
ENSRNOT00060050823
resolver
enst
ENSRNOT00065051510
resolver
genesymbol
Acta2
resolver
genesymbol_syn
Actsa
resolver
genesymbol_syn
Actvs
resolver
uniprot
B0BMT0
resolver
uniprot
P03996
resolver
uniprot
P04108
resolver
uniprot
P70476
resolver
uniprot_entry
ACTA_RAT
resolver
uniprot_entry
B0BMT0_RAT
resolver
uniprot_sec
P03996
resolver
uniprot_sec
P04108
resolver
uniprot_sec
P70476
resolver
amino_acid_sequence
MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
uniprot
proteins
mass_dalton
42009
uniprot
proteins
post_translational_modification
PTM: [Actin, aortic smooth muscle, intermediate form]: N-terminal cleavage of acetylated cysteine of intermediate muscle actin by ACTMAP. {ECO:0000250|UniProtKB:P62737}.; PTM: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization. {ECO:0000250|UniProtKB:P62737}.; PTM: Monomethylation at Lys-86 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration (By similarity). {ECO:0000250}.; PTM: Methylated at His-75 by SETD3. {ECO:0000250|UniProtKB:P62736}.
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
3234770
uniprot
proteins
pubmed
3375082
uniprot
proteins
pubmed
6546444
uniprot
proteins
sequence_length
377
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
uniprot
proteins