Sat1
entrez
20229
canonical
uniprot
P48026
canonical
ensembl
ENSMUSG00000025283
resolver
ensp
ENSMUSP00000026318
resolver
ensp
ENSMUSP00000108170
resolver
enst
ENSMUST00000026318
resolver
enst
ENSMUST00000112551
resolver
genesymbol
Sat1
resolver
genesymbol_syn
Sat
resolver
uniprot
A2BES2
resolver
uniprot
Q3U444
resolver
uniprot
Q3V2Q2
resolver
uniprot_entry
A2BES2_MOUSE
resolver
uniprot_entry
Q3V2Q2_MOUSE
resolver
uniprot_entry
SAT1_MOUSE
resolver
uniprot_sec
Q3U444
resolver
amino_acid_sequence
MAKFKIRPATASDCSDILRLIKELAKYEYMEDQVILTEKDLQEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMKCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMAAEE
uniprot
proteins
ec_number
2.3.1.57
uniprot
proteins
function
FUNCTION: Enzyme which catalyzes the acetylation of polyamines (PubMed:18690703). Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine (By similarity). This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines (By similarity). Also involved in the regulation of polyamine transport out of cells (By similarity). Also acts on 1,3-diaminopropane and 1,5-diaminopentane (By similarity). {ECO:0000250|UniProtKB:P21673, ECO:0000305|PubMed:18690703}.
uniprot
proteins
mass_dalton
20012
uniprot
proteins
mutagenesis
MUTAGEN 92; /note="E->Q: Reduced activity."; /evidence="ECO:0000269|PubMed:18690703"; MUTAGEN 93; /note="D->N: Reduced activity."; /evidence="ECO:0000269|PubMed:18690703
uniprot
proteins
pathway_participation
PATHWAY: Amine and polyamine degradation; putrescine degradation; N-acetylputrescine from putrescine: step 1/1. {ECO:0000305|PubMed:18690703}.
uniprot
proteins
protein_family
Acetyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18690703
uniprot
proteins
pubmed
8241266
uniprot
proteins
sequence_length
171
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P21673}.
uniprot
proteins