P54758
uniprot
P54758
canonical
amino_acid_sequence
MGGCEVREFLLQFGFFLPLLTAWTGDCSHVSNQVVLLDTSTVMGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFTLYYIESDESHGTKFKPSQYIKIDTIAADESFTQMDLGDRILKLNTEVREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSSEERDTPKLYCGADGDWLVPLGRCICTTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSSTFVEATSVCHCEKGYFRAEKDPPSMACTRPPSAPRNVAFNINETALILEWSPPSDTGGRKDLTYSVICKKCGVDASQCEDCGAGLRFIPRPTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELSISPKPFTAITVTTDQDAPSLIGMMRKDWASQNSLALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATTYIFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRTHLQNSHLRFPGIKTYIDPDTYEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGDVPEYPLFVTVGDWLDSIKMGQYKSNFMAAGFTTFDLISRMSIEDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
uniprot
proteins
ec_number
2.7.10.1
uniprot
proteins
function
FUNCTION: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
116209
uniprot
proteins
protein_family
Ephrin receptor subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Tyr protein kinase family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
7504232
uniprot
proteins
sequence_length
1035
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 550..570; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins