PRDM15
entrez
63977
canonical
uniprot
P57071
canonical
ensembl
ENSG00000141956
resolver
ensp
ENSP00000269844
resolver
ensp
ENSP00000381556
resolver
ensp
ENSP00000408592
resolver
ensp
ENSP00000431410
resolver
ensp
ENSP00000597609
resolver
enst
ENST00000447016
resolver
genesymbol
PRDM15
resolver
genesymbol_syn
C21orf83
resolver
genesymbol_syn
ZNF298
resolver
hgnc
HGNC:13999
resolver
uniprot
E7ER26
resolver
uniprot
E9PDJ6
resolver
uniprot
E9PF37
resolver
uniprot
E9PGL3
resolver
uniprot
E9PL97
resolver
uniprot
Q4W8S0
resolver
uniprot
Q4W8S3
resolver
uniprot
Q4W8S4
resolver
uniprot
Q4W8S5
resolver
uniprot
Q8N0X3
resolver
uniprot
Q8NEX0
resolver
uniprot
Q9NQV3
resolver
uniprot_entry
E7ER26_HUMAN
resolver
uniprot_entry
PRD15_HUMAN
resolver
uniprot_sec
E9PDJ6
resolver
uniprot_sec
E9PF37
resolver
uniprot_sec
E9PGL3
resolver
uniprot_sec
E9PL97
resolver
uniprot_sec
Q4W8S0
resolver
uniprot_sec
Q4W8S3
resolver
uniprot_sec
Q4W8S4
resolver
uniprot_sec
Q4W8S5
resolver
uniprot_sec
Q8N0X3
resolver
uniprot_sec
Q8NEX0
resolver
uniprot_sec
Q9NQV3
resolver
amino_acid_sequence
MAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPPNLEIRRLEDGAEGVFAITQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPAAEAEHQNLTAYQHGSDVYFTTSRDIPPGTELRVWYAAFYAKKMDKPMLKQAGSGVHAAGTPENSAPVESEPSQWACKVCSATFLELQLLNEHLLGHLEQAKSLPPGSQSEAAAPEKEQDTPRGEPPAVPESENVATKEQKKKPRRGRKPKVSKAEQPLVIVEDKEPTEQVAEIITEVPPDEPVSATPDERIMELVLGKLATTTTDTSSVPKFTHHQNNTITLKRSLILSSRHGIRRKLIKQLGEHKRVYQCNICSKIFQNSSNLSRHVRSHGDKLFKCEECAKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGTCEKTFRIESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLEGVRRVKREDLEAGGENLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRRFAQKVNMLKHCKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPELTLEQEDLAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDATFSEYSEKETEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTAAATQFTNLQPVAVGHLTTPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQLSDQHPLTWRAVPQTDVLPPSQPQAPPQQAAQPQVQAEQQQQQMYSY
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development (By similarity). Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming (PubMed:28740264). {ECO:0000250|UniProtKB:E9Q8T2, ECO:0000269|PubMed:28740264}.
uniprot
proteins
mass_dalton
129585
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
12036297
uniprot
proteins
pubmed
12036298
uniprot
proteins
pubmed
15904895
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
28740264
uniprot
proteins
pubmed
40608935
uniprot
proteins
sequence_length
1141
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15904895}.
uniprot
proteins