MAPK8IP2
entrez
23542
canonical
uniprot
Q13387
canonical
ensembl
ENSG00000008735
resolver
ensp
ENSP00000330572
resolver
ensp
ENSP00000548464
resolver
ensp
ENSP00000548465
resolver
ensp
ENSP00000548466
resolver
genesymbol
MAPK8IP2
resolver
genesymbol_syn
IB2
resolver
genesymbol_syn
JIP2
resolver
genesymbol_syn
PRKM8IPL
resolver
hgnc
HGNC:6883
resolver
uniprot
Q96G62
resolver
uniprot
Q99771
resolver
uniprot
Q9NZ59
resolver
uniprot
Q9UKQ4
resolver
uniprot_entry
JIP2_HUMAN
resolver
uniprot_sec
Q96G62
resolver
uniprot_sec
Q99771
resolver
uniprot_sec
Q9NZ59
resolver
uniprot_sec
Q9UKQ4
resolver
amino_acid_sequence
MADRAEMFSLSTFHSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE
uniprot
proteins
function
FUNCTION: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
87975
uniprot
proteins
protein_family
JIP scaffold family
uniprot
proteins
pubmed
10490659
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
10756100
uniprot
proteins
pubmed
11378392
uniprot
proteins
pubmed
12529303
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9110174
uniprot
proteins
sequence_length
824
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10490659}. Note=Accumulates in cell surface projections. {ECO:0000269|PubMed:10490659}.
uniprot
proteins