FKBP3
entrez
2287
canonical
uniprot
Q00688
canonical
ensembl
ENSG00000100442
resolver
ensp
ENSP00000216330
resolver
ensp
ENSP00000379374
resolver
enst
ENST00000216330
resolver
enst
ENST00000396062
resolver
genesymbol
FKBP3
resolver
genesymbol_syn
FKBP25
resolver
hgnc
HGNC:3719
resolver
uniprot
B2R4Q9
resolver
uniprot
Q14317
resolver
uniprot_entry
FKBP3_HUMAN
resolver
uniprot_sec
B2R4Q9
resolver
uniprot_sec
Q14317
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited preferentially by rapamycin over FK506.
uniprot
proteins
amino_acid_sequence
MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
uniprot
proteins
ec_number
5.2.1.8
uniprot
proteins
function
FUNCTION: FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
uniprot
proteins
mass_dalton
25177
uniprot
proteins
protein_family
FKBP-type PPIase family
uniprot
proteins
pubmed
1374240
uniprot
proteins
pubmed
1375932
uniprot
proteins
pubmed
1376117
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
224
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins