DEDD2
entrez
162989
canonical
uniprot
Q8WXF8
canonical
ensembl
ENSG00000160570
resolver
ensp
ENSP00000336972
resolver
ensp
ENSP00000470082
resolver
ensp
ENSP00000471512
resolver
ensp
ENSP00000671167
resolver
ensp
ENSP00000671168
resolver
genesymbol
DEDD2
resolver
genesymbol_syn
FLAME3
resolver
hgnc
HGNC:24450
resolver
uniprot
Q8NBR2
resolver
uniprot
Q8NES1
resolver
uniprot
Q8TAA8
resolver
uniprot
Q96D35
resolver
uniprot_entry
DEDD2_HUMAN
resolver
uniprot_sec
Q8NBR2
resolver
uniprot_sec
Q8NES1
resolver
uniprot_sec
Q8TAA8
resolver
uniprot_sec
Q96D35
resolver
amino_acid_sequence
MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTSSSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQQQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS
uniprot
proteins
function
FUNCTION: May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
uniprot
proteins
mass_dalton
36179
uniprot
proteins
pubmed
11741985
uniprot
proteins
pubmed
11965497
uniprot
proteins
pubmed
12235123
uniprot
proteins
pubmed
12527898
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
sequence_length
326
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:11965497}. Note=Nuclear, accumulated in subnuclear structures resembling nucleoli.
uniprot
proteins