P3h4
entrez
66180
canonical
uniprot
Q8K2B0
canonical
ensembl
ENSMUSG00000006931
resolver
ensp
ENSMUSP00000065278
resolver
ensp
ENSMUSP00000239983
resolver
enst
ENSMUST00000066489
resolver
genesymbol
P3h4
resolver
genesymbol_syn
Leprel4
resolver
genesymbol_syn
Sc65
resolver
uniprot_entry
SC65_MOUSE
resolver
amino_acid_sequence
MARGAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLATAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPATSQPRPASGPDGDHDGDGEDWARELRLFGHVLERAACLRRCKKTLPAFQVPYPPRQLLRDFQSRLPYQYLHYAHFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYRGMLDIGDESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALAEYMTVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCETNLTPNVGGFFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEDEDFQPREEAMLYHNQTSELRELLDFTHMYLQSDDEMELEETESLPEPEEPLSDAEFEGEGDYEEGLYADWWQEPEAKGDEAEAEPEPELT
uniprot
proteins
function
FUNCTION: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils (PubMed:27119146). Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly (PubMed:23959653, PubMed:27119146, PubMed:28115524). {ECO:0000269|PubMed:23959653, ECO:0000269|PubMed:27119146, ECO:0000269|PubMed:28115524}.
uniprot
proteins
mass_dalton
51132
uniprot
proteins
protein_family
Leprecan family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
23959653
uniprot
proteins
pubmed
27119146
uniprot
proteins
pubmed
28115524
uniprot
proteins
sequence_length
443
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q92791}.
uniprot
proteins