TEKT4
entrez
150483
canonical
uniprot
Q8WW24
canonical
ensembl
ENSG00000163060
resolver
ensp
ENSP00000295201
resolver
ensp
ENSP00000611755
resolver
ensp
ENSP00000773793
resolver
enst
ENST00000295201
resolver
genesymbol
TEKT4
resolver
hgnc
HGNC:31012
resolver
uniprot
A0A384MEB7
resolver
uniprot_entry
A0A384MEB7_HUMAN
resolver
uniprot_entry
TEKT4_HUMAN
resolver
amino_acid_sequence
MAQTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGYQ
uniprot
proteins
function
FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:36191189). Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). Contributes to normal sperm motility (By similarity). {ECO:0000250|UniProtKB:Q2TA38, ECO:0000250|UniProtKB:Q6X6Z7, ECO:0000269|PubMed:36191189}.
uniprot
proteins
mass_dalton
50649
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. {ECO:0000250|UniProtKB:Q149S1}.
uniprot
proteins
protein_family
Tektin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17244819
uniprot
proteins
pubmed
36191189
uniprot
proteins
sequence_length
435
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:36191189}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q149S1}. Note=Found in the abaxial (convex) surface of outer dense fibers in sperm flagella. {ECO:0000250|UniProtKB:Q149S1}.
uniprot
proteins