GPD2
entrez
2820
canonical
uniprot
P43304
canonical
ensembl
ENSG00000115159
resolver
ensp
ENSP00000308610
resolver
ensp
ENSP00000386425
resolver
ensp
ENSP00000409708
resolver
ensp
ENSP00000563662
resolver
ensp
ENSP00000563664
resolver
ensp
ENSP00000563669
resolver
genesymbol
GPD2
resolver
hgnc
HGNC:4456
resolver
uniprot
A8K4V0
resolver
uniprot
B3KSA9
resolver
uniprot
Q59FR1
resolver
uniprot
Q9HAP9
resolver
uniprot_entry
GPDM_HUMAN
resolver
uniprot_sec
A8K4V0
resolver
uniprot_sec
B3KSA9
resolver
uniprot_sec
Q59FR1
resolver
uniprot_sec
Q9HAP9
resolver
activity_regulation
ACTIVITY REGULATION: Calcium-binding enhance the activity of the enzyme. {ECO:0000269|PubMed:9070847}.
uniprot
proteins
amino_acid_sequence
MAFQKAVKGTILVGGGALATVLGLSQFAHYRRKQMNLAYVKAADCISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPIMLPVYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPQTGKVRVSGARCKDVLTGQEFDVRAKCVINATGPFTDSVRKMDDKDAAAICQPSAGVHIVMPGYYSPESMGLLDPATSDGRVIFFLPWQKMTIAGTTDTPTDVTHHPIPSEEDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDPKSADTQSISRNHVVDISESGLITIAGGKWTTYRSMAEDTINAAVKTHNLKAGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAATYGDKAFEVAKMASVTGKRWPIVGVRLVSEFPYIEAEVKYGIKEYACTAVDMISRRTRLAFLNVQAAEEALPRIVELMGRELNWDDYKKQEQLETARKFLYYEMGYKSRSEQLTDRSEISLLPSDIDRYKKRFHKFDADQKGFITIVDVQRVLESINVQMDENTLHEILNEVDLNKNGQVELNEFLQLMSAIQKGRVSGSRLAILMKTAEENLDRRVPIPVDRSCGGL
uniprot
proteins
ec_number
1.1.5.3
uniprot
proteins
function
FUNCTION: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device. {ECO:0000269|PubMed:9070847}.
uniprot
proteins
mass_dalton
80853
uniprot
proteins
pathway_participation
PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. {ECO:0000269|PubMed:9070847}.
uniprot
proteins
protein_family
FAD-dependent glycerol-3-phosphate dehydrogenase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
7821823
uniprot
proteins
pubmed
8549872
uniprot
proteins
pubmed
8682323
uniprot
proteins
pubmed
9070847
uniprot
proteins
pubmed
9110174
uniprot
proteins
sequence_length
727
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion.
uniprot
proteins