RGS5
entrez
8490
canonical
uniprot
O15539
canonical
ensembl
ENSG00000143248
resolver
ensp
ENSP00000319308
resolver
ensp
ENSP00000432313
resolver
ensp
ENSP00000433001
resolver
ensp
ENSP00000480891
resolver
genesymbol
RGS5
resolver
hgnc
HGNC:10001
resolver
uniprot
E9PMP5
resolver
uniprot
Q53XA9
resolver
uniprot
Q599J0
resolver
uniprot_entry
RGS5_HUMAN
resolver
uniprot_sec
E9PMP5
resolver
uniprot_sec
Q53XA9
resolver
uniprot_sec
Q599J0
resolver
amino_acid_sequence
MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK
uniprot
proteins
function
FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
20946
uniprot
proteins
pubmed
10471929
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15670159
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
9747037
uniprot
proteins
sequence_length
181
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:15670159}. Membrane {ECO:0000269|PubMed:15670159}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:15670159}.
uniprot
proteins