PARP15
entrez
165631
canonical
uniprot
Q460N3
canonical
ensembl
ENSG00000173200
resolver
ensp
ENSP00000308436
resolver
ensp
ENSP00000417214
resolver
ensp
ENSP00000417785
resolver
ensp
ENSP00000419488
resolver
ensp
ENSP00000570410
resolver
ensp
ENSP00000570411
resolver
ensp
ENSP00000570412
resolver
ensp
ENSP00000570413
resolver
enst
ENST00000483793
resolver
enst
ENST00000493645
resolver
genesymbol
PARP15
resolver
genesymbol_syn
BAL3
resolver
hgnc
HGNC:26876
resolver
uniprot
B7ZL48
resolver
uniprot
C9J7L3
resolver
uniprot
F6WN22
resolver
uniprot
J3KR47
resolver
uniprot
Q8N1K3
resolver
uniprot_entry
B7ZL48_HUMAN
resolver
uniprot_entry
C9J7L3_HUMAN
resolver
uniprot_entry
F6WN22_HUMAN
resolver
uniprot_entry
PAR15_HUMAN
resolver
uniprot_sec
J3KR47
resolver
uniprot_sec
Q8N1K3
resolver
amino_acid_sequence
MAAPGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREAGSVLPAGNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFTA
uniprot
proteins
ec_number
2.4.2.-
uniprot
proteins
function
FUNCTION: Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins (PubMed:16061477, PubMed:25043379, PubMed:25635049). Acts as a negative regulator of transcription (PubMed:16061477). {ECO:0000269|PubMed:16061477, ECO:0000269|PubMed:25043379, ECO:0000269|PubMed:25635049}.
uniprot
proteins
mass_dalton
74576
uniprot
proteins
mutagenesis
MUTAGEN 559; /note="H->Y: Abolishes catalytic activity."; /evidence="ECO:0000269|PubMed:25635049"; MUTAGEN 560; /note="G->A: Slightly reduces catalytic activity. Abolishes activity; when associated with Y-559 and C-604."; /evidence="ECO:0000269|PubMed:25635049"; MUTAGEN 604; /note="Y->C: Reduces catalytic activity 20-fold. Abolishes activity; when associated with Y-559 and A-560."; /evidence="ECO:0000269|PubMed:25635049
uniprot
proteins
protein_family
ARTD/PARP family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16061477
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
20106667
uniprot
proteins
pubmed
22823910
uniprot
proteins
pubmed
23473667
uniprot
proteins
pubmed
25043379
uniprot
proteins
pubmed
25635049
uniprot
proteins
sequence_length
678
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305|PubMed:16061477}.
uniprot
proteins