Tekt2
entrez
24084
canonical
uniprot
Q922G7
canonical
ensembl
ENSMUSG00000028845
resolver
ensp
ENSMUSP00000030658
resolver
ensp
ENSMUSP00000099676
resolver
enst
ENSMUST00000030658
resolver
enst
ENSMUST00000102616
resolver
genesymbol
Tekt2
resolver
uniprot
Q9WVR0
resolver
uniprot_entry
TEKT2_MOUSE
resolver
uniprot_sec
Q9WVR0
resolver
amino_acid_sequence
MATLSFKPSERYRLSDWRTNSYLLSTNAERQRDASHQIRQEARILRNETNNQIVWDEHDNRTRLAERIDTVNRWKETLDKCLTDLDAEIDSLAQAKESAEQNLQAKNLPLDVAIECLTLRESRRDIDVVRDPVEEELLKEVEVIEATKKVLQEKISQAFQHLCLLQEIRQQLNSDHRDKMETLEIDRGCLSLNLTSPNISLKVNPTRIPKDSTTLQQWDEFTRFNKNRAEAEMKASIELREAIALAIAQTNNELDAQRVATEFTFRKRLREMESFYSELKWQEKNTLEEIAELQGDIRRLEEDLRRKMMNLKLAHTRLESRTYRSNVELCRDQTQYGLIDEVHQLEATINTMKQKLAQTQNALDALFKHLARIQADIACKTNTLLLDTKCMDTRRKLTVPAEKFVPQVDTFTRTTNRTLSPLKICQLELT
uniprot
proteins
function
FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:15340058, PubMed:37295417, PubMed:37865089, PubMed:37989994). Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia (PubMed:15340058). Forms filamentous polymers in the walls of ciliary and flagellar microtubules (PubMed:15340058). {ECO:0000269|PubMed:15340058, ECO:0000269|PubMed:37295417, ECO:0000269|PubMed:37865089, ECO:0000269|PubMed:37989994}.
uniprot
proteins
mass_dalton
50311
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. {ECO:0000269|PubMed:36206347}.; PTM: Tyrosine phosphorylated. {ECO:0000250|UniProtKB:Q1W6C3}.
uniprot
proteins
protein_family
Tektin family
uniprot
proteins
pubmed
10456331
uniprot
proteins
pubmed
15340058
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24394471
uniprot
proteins
pubmed
35547804
uniprot
proteins
pubmed
36206347
uniprot
proteins
pubmed
37295417
uniprot
proteins
pubmed
37865089
uniprot
proteins
pubmed
37989994
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:15340058}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:10456331, ECO:0000269|PubMed:37295417, ECO:0000269|PubMed:37865089, ECO:0000269|PubMed:37989994}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000269|PubMed:24394471}. Note=Colocalized with CCDC172 at the perinuclear region (PubMed:24394471). {ECO:0000269|PubMed:24394471}.
uniprot
proteins