Tdrd3
entrez
219249
canonical
uniprot
Q91W18
canonical
ensembl
ENSMUSG00000022019
resolver
ensp
ENSMUSP00000129019
resolver
ensp
ENSMUSP00000131542
resolver
ensp
ENSMUSP00000197318
resolver
genesymbol
Tdrd3
resolver
uniprot
E9Q2Q4
resolver
uniprot
Q6NZG7
resolver
uniprot
Q8BZW6
resolver
uniprot
Q8C1A4
resolver
uniprot_entry
TDRD3_MOUSE
resolver
uniprot_sec
E9Q2Q4
resolver
uniprot_sec
Q6NZG7
resolver
uniprot_sec
Q8BZW6
resolver
uniprot_sec
Q8C1A4
resolver
amino_acid_sequence
MAEVSGAALSQAGWYLSDEGVEACTSSPGKGSINDIILIALNTDLRTIGKKFLPSDINGGKVEKLEGPCVLQIQKVRNVAAPKDNEESQAAPRMLRVQMTDGHTSCTAVEFSYISKISLNTPPGTKVKLSGTVDIKNGFLLLSDSNTTVLGGEVEHLIDKWALQRSLLKHNRSNIGAEGGPPPFLPFGQKCASNVQVDSRELDRRKTLQVSLPAKPANDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNIGAAGHRNREVLQKEKASKSESKNEGVYRELVDEKALKHITEMGFSKEASRQALMDNANNLEAALNVLLNSSKQKPAVGPPARGRGKGRGRGRSEDEEDLGTARPSAPSTLFDFLESKMGTLNVEEPKSQPQHLHQGQHRGWNAEQNGMKDGTQSRHLPRNDTRQPRNERPPRFQKDTPTSKSTVENSVLSRNRGSERPSSSSGSDVWAEERIKCDRPYSRYDRTKDASHPLGLQHNDGAFKKRENSMQNRPGRGPLYAEAKENPLPPEFVDYNNQRRGRRENQTGHPDHCYERKPRTMNSEAVSGLKIEKHFSVNTDYPRPVQSNSLGVPNGETAPPLKGRRVGPIKSAGPVTAVPYDDKIFYNSGPKRRSGPIKPEKVIESSIPVEYAKVWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFTDYGNYEEVLLSNIKPVQTEAWEEEGTYDHTIEFRRGGDGQPRRSTRPTQQFYQPPRARN
uniprot
proteins
function
FUNCTION: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. {ECO:0000250|UniProtKB:Q9H7E2}.
uniprot
proteins
mass_dalton
82253
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
743
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H7E2}. Nucleus {ECO:0000250|UniProtKB:Q9H7E2}. Note=Predominantly cytoplasmic. Associated with actively translating polyribosomes. Component of stress granules. {ECO:0000250|UniProtKB:Q9H7E2}.
uniprot
proteins