Kif3a
entrez
16568
canonical
uniprot
P28741
canonical
ensembl
ENSMUSG00000018395
resolver
ensp
ENSMUSP00000056197
resolver
ensp
ENSMUSP00000112782
resolver
ensp
ENSMUSP00000113848
resolver
ensp
ENSMUSP00000133432
resolver
ensp
ENSMUSP00000264073
resolver
enst
ENSMUST00000057330
resolver
enst
ENSMUST00000118353
resolver
enst
ENSMUST00000120613
resolver
enst
ENSMUST00000173744
resolver
genesymbol
Kif3a
resolver
genesymbol_syn
AW124694
resolver
genesymbol_syn
Kif3
resolver
uniprot
B1AQZ2
resolver
uniprot
F6ZEG5
resolver
uniprot
G3UWU9
resolver
uniprot
Q3TET1
resolver
uniprot
Q3UF02
resolver
uniprot
Q3UI47
resolver
uniprot
Q7TSZ7
resolver
uniprot_entry
B1AQZ2_MOUSE
resolver
uniprot_entry
F6ZEG5_MOUSE
resolver
uniprot_entry
G3UWU9_MOUSE
resolver
uniprot_entry
KIF3A_MOUSE
resolver
uniprot_entry
Q3TET1_MOUSE
resolver
uniprot_entry
Q3UF02_MOUSE
resolver
uniprot_entry
Q3UI47_MOUSE
resolver
uniprot_sec
Q7TSZ7
resolver
amino_acid_sequence
MPINKSEKPESCDNVKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEVSGSDISGSEEDDEEGELGEDGEKKKKRRDQAGKKKVSPDKMVEMQAKIDEERKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRRRAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPQDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKERDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKMGRRKRSAKPETVIDSLLQ
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Microtubule-based anterograde translocator for membranous organelles, such as primary cilium and centriole (PubMed:18497258, PubMed:21670265, PubMed:23386061, PubMed:7559760). Shows a plus end-directed microtubule sliding activity in vitro (PubMed:7559760). Plays a role in primary cilia formation, probably by mediating transport of proteins into primary cilia (PubMed:18497258, PubMed:21670265, PubMed:39138140). Mediates smoothened (SMO) translocation into primary cilia in response to hedgehog morphogens (PubMed:18497258, PubMed:39138140). Plays a role in centriole cohesion and subdistal appendage organization and function (PubMed:23386061). Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole (PubMed:23386061). Also required for ciliary basal feet formation and microtubule anchoring to mother centriole (PubMed:23386061). {ECO:0000269|PubMed:18497258, ECO:0000269|PubMed:21670265, ECO:0000269|PubMed:23386061, ECO:0000269|PubMed:39138140, ECO:0000269|PubMed:7559760}.
uniprot
proteins
mass_dalton
80170
uniprot
proteins
protein_family
Kinesin II subfamily
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
1447303
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18497258
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20643351
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21670265
uniprot
proteins
pubmed
23386061
uniprot
proteins
pubmed
39138140
uniprot
proteins
pubmed
7559760
uniprot
proteins
sequence_length
701
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305|PubMed:21670265}. Cell projection, cilium {ECO:0000269|PubMed:18497258, ECO:0000269|PubMed:21670265}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23386061}. Note=Localizes to the subdistal appendage region of the centriole. {ECO:0000269|PubMed:23386061}.
uniprot
proteins