Ggh
entrez
14590
canonical
uniprot
Q9Z0L8
canonical
ensembl
ENSMUSG00000073987
resolver
ensp
ENSMUSP00000095843
resolver
ensp
ENSMUSP00000295802
resolver
genesymbol
Ggh
resolver
uniprot
B1AWC1
resolver
uniprot
Q9Z0L7
resolver
uniprot_entry
GGH_MOUSE
resolver
uniprot_sec
B1AWC1
resolver
uniprot_sec
Q9Z0L7
resolver
amino_acid_sequence
MANLGYLLCLLGLLLCGLSSPGMSRPYNHGSERPIIGVVMQECFGKMAKLGNYYIAASYVKYIESAGARVVPIRPDLSDAEYEELFRSINGVLLPGGGANLTDSGYSRVAKIFFSKALESFDNGDHFPVWGTCLGFEELSVLVSGENLLTSTDTKSKKLPLNFTEGARKSRMFKHFPTELLDSLALENLTANFHKWSLSVKNFTENEKLKKFFNILTTNTDGKTEFISSMEGFKYPVYAVQWHPEKAAFEWKNLGGISHAPNAVKTSFYLAEFLVSEARKNSHHFENVVKETASLIYKFNPIYTGNISSFQQAYMFD
uniprot
proteins
ec_number
3.4.19.9
uniprot
proteins
function
FUNCTION: Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. {ECO:0000250|UniProtKB:Q92820}.
uniprot
proteins
mass_dalton
35470
uniprot
proteins
protein_family
Peptidase C26 family
uniprot
proteins
pubmed
10393243
uniprot
proteins
pubmed
16170054
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9756990
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000250|UniProtKB:Q92820}. Lysosome {ECO:0000250|UniProtKB:Q92820}. Melanosome {ECO:0000250|UniProtKB:Q92820}. Note=While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:Q92820}.
uniprot
proteins