LCE3A
entrez
353142
canonical
uniprot
Q5TA76
canonical
ensembl
ENSG00000185962
resolver
ensp
ENSP00000335006
resolver
enst
ENST00000335674
resolver
genesymbol
LCE3A
resolver
genesymbol_syn
LEP13
resolver
hgnc
HGNC:29461
resolver
uniprot_entry
LCE3A_HUMAN
resolver
amino_acid_sequence
MSCQQNQQQCQPPPKCPAKSPAQCLPPASSSCAPSSGGCGPSSERSCCLSHHRCRRSHRCRCQSSNSCDRGSGQQGGSSSCGHSSAGCC
uniprot
proteins
function
FUNCTION: A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035). {ECO:0000269|PubMed:28634035, ECO:0000305|PubMed:28634035}.
uniprot
proteins
mass_dalton
9146
uniprot
proteins
protein_family
LCE family
uniprot
proteins
pubmed
15854049
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
28634035
uniprot
proteins
pubmed
36804407
uniprot
proteins
sequence_length
89
uniprot
proteins