Hsd3b6
entrez
29632
canonical
uniprot
Q62878
canonical
ensembl
ENSRNOG00000019441
resolver
ensp
ENSRNOP00000026306
resolver
enst
ENSRNOT00000026306
resolver
genesymbol
Hsd3b6
resolver
uniprot
Q5FVK0
resolver
uniprot_entry
3BHS4_RAT
resolver
uniprot_sec
Q5FVK0
resolver
amino_acid_sequence
MPGWSCLVTGAGGFLGQRIVQLLVQEKDLKEVRVLDKVFRPETREEFFNLGTSIKVTVLEGDILDTQCLRRACQGISVVIHTAALIDVTGVNPRQTILDVNLKGTQNLLEACVQASVPAFIYCSTVDVAGPNSYKKIILNGHEEEHHESTWSNPYPYSKKMAEKAVLAANGSILKNGGTLHTCALRPMYIYGERSPFLSVMILAALKSKGILNVTGKFSIANPVYVGNVAWAHILAARGLRDPKKSQNVQGQFYYISDDTPHQSYDDLNYTLSKEWGLHLDSSWSLPLPLLYWLAFLLEIVSFFLHPVYNYRPSFNRHLVTLSNSKFTFSYKKAQRDLGYKPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
uniprot
proteins
ec_number
1.1.1.145
uniprot
proteins
ec_number
5.3.3.1
uniprot
proteins
function
FUNCTION: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
uniprot
proteins
mass_dalton
41957
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; steroid biosynthesis.
uniprot
proteins
protein_family
3-beta-HSD family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7690038
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins