AFM
entrez
173
canonical
uniprot
P43652
canonical
ensembl
ENSG00000079557
resolver
ensp
ENSP00000226355
resolver
ensp
ENSP00000523661
resolver
ensp
ENSP00000651582
resolver
ensp
ENSP00000651596
resolver
ensp
ENSP00000651599
resolver
enst
ENST00000226355
resolver
enst
ENST00000853602
resolver
genesymbol
AFM
resolver
genesymbol_syn
ALB2
resolver
genesymbol_syn
ALBA
resolver
hgnc
HGNC:316
resolver
uniprot
A8K3E1
resolver
uniprot
Q32MR3
resolver
uniprot
Q4W5C5
resolver
uniprot_entry
AFAM_HUMAN
resolver
uniprot_sec
A8K3E1
resolver
uniprot_sec
Q32MR3
resolver
uniprot_sec
Q4W5C5
resolver
amino_acid_sequence
MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFGELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN
uniprot
proteins
function
FUNCTION: Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed:26902720). Binds vitamin E (PubMed:12463752, PubMed:15952736). May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient (PubMed:15952736). May be involved in the transport of vitamin E across the blood-brain barrier (PubMed:19046407). {ECO:0000269|PubMed:12463752, ECO:0000269|PubMed:15952736, ECO:0000269|PubMed:19046407, ECO:0000269|PubMed:26902720, ECO:0000305}.
uniprot
proteins
mass_dalton
69069
uniprot
proteins
post_translational_modification
PTM: N-glycosylated; more than 90% of the glycans are sialylated. {ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15952736, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:29153507}.
uniprot
proteins
protein_family
ALB/AFP/VDB family
uniprot
proteins
pubmed
12463752
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14760718
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
15952736
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16740002
uniprot
proteins
pubmed
19046407
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
19838169
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
26902720
uniprot
proteins
pubmed
29153507
uniprot
proteins
pubmed
7517938
uniprot
proteins
pubmed
7875606
uniprot
proteins
pubmed
8755513
uniprot
proteins
sequence_length
599
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12463752, ECO:0000269|PubMed:15952736, ECO:0000269|PubMed:26902720, ECO:0000269|PubMed:7517938}.
uniprot
proteins