Inhibition of host DNA replication by virus
uniprot_keyword
KW-1248
canonical
name
Inhibition of host DNA replication by virus
uniprot
definition
Viral protein that blocks host DNA replication without inhibiting host transcription or translation. Inhibiting host replication provides an advantage during the virus life cycle by reducing or eliminating competing host macromolecular synthesis. Bacteriophage N4 for example is known to shut off the host DNA replication while the host genome remains structurally intact. Bacteriophage lambda prevents host DNA replication initiation and Staphylococcus bacteriophages target the replicative DNA polymerase processivity clamp and the helicase.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords