AMHR2
entrez
269
canonical
uniprot
Q16671
canonical
ensembl
ENSG00000135409
resolver
ensp
ENSP00000257863
resolver
ensp
ENSP00000369117
resolver
ensp
ENSP00000446661
resolver
ensp
ENSP00000633624
resolver
ensp
ENSP00000690545
resolver
ensp
ENSP00000690547
resolver
ensp
ENSP00000690548
resolver
genesymbol
AMHR2
resolver
genesymbol_syn
AMHR
resolver
genesymbol_syn
MISR2
resolver
hgnc
HGNC:465
resolver
uniprot
A0AVE1
resolver
uniprot
B9EGB7
resolver
uniprot
E9PGD2
resolver
uniprot
F8W1D2
resolver
uniprot
Q13762
resolver
uniprot
Q647K2
resolver
uniprot_entry
AMHR2_HUMAN
resolver
uniprot_sec
A0AVE1
resolver
uniprot_sec
B9EGB7
resolver
uniprot_sec
E9PGD2
resolver
uniprot_sec
F8W1D2
resolver
uniprot_sec
Q13762
resolver
uniprot_sec
Q647K2
resolver
amino_acid_sequence
MLGSLGLWALLPTAVEAPPNRRTCVFFEAPGVRGSTKTLGELLDTGTELPRAIRCLYSRCCFGIWNLTQDRAQVEMQGCRDSDEPGCESLHCDPSPRAHPSPGSTLFTCSCGTDFCNANYSHLPPPGSPGTPGSQGPQAAPGESIWMALVLLGLFLLLLLLLGSIILALLQRKNYRVRGEPVPEPRPDSGRDWSVELQELPELCFSQVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGGPGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNTPTSDELWALAVQERRRPYIPSTWRCFATDPDGLRELLEDCWDADPEARLTAECVQQRLAALAHPQESHPFPESCPRGCPPLCPEDCTSIPAPTILPCRPQRSACHFSVQQGPCSRNPQPACTLSPV
uniprot
proteins
disease_involvement
DISEASE: Persistent Muellerian duct syndrome 2 (PMDS2) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. {ECO:0000269|PubMed:11549681, ECO:0000269|PubMed:8872466}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
2.7.11.30
uniprot
proteins
function
FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
uniprot
proteins
mass_dalton
62750
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
TGFB receptor subfamily
uniprot
proteins
protein_family
TKL Ser/Thr protein kinase family
uniprot
proteins
pubmed
10589763
uniprot
proteins
pubmed
11549681
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
17911401
uniprot
proteins
pubmed
7488027
uniprot
proteins
pubmed
7493017
uniprot
proteins
pubmed
8872466
uniprot
proteins
sequence_length
573
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 150..170; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins