Eid3
entrez
691688
canonical
uniprot
Q4V8G2
canonical
ensembl
ENSRNOG00000075657
resolver
ensp
ENSRNOP00000109585
resolver
genesymbol
Eid3
resolver
uniprot_entry
EID3_RAT
resolver
amino_acid_sequence
MSEEKCSLTGGEEKGEELARSLAWQHLVKQAEEDDDDDEEALKKEEEEEEEEEEEDEEEEEEGPDSSSDDLSPEAPCMHPDLLELAVDREKCRSIRRQYRQLIYTVQQNREDIVNTASDSLTEALEEANVLFDGVSRTREAALDAQFLVLASDLGKEKAKQLNSDMSFFNHVAFCELLLVFVGLNWMEEECEELSECDESIALSFWNMLHKEATAWMLQAETFHFIFGSFKAERSARKPRQEHHKRACKMEGNGDMPTKLRKLDVHANQETTEKEVERILGLLQTYFQKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIIRDGFARIRLDQDRLPILEPTNVNQVDEENDSCSYCRKQGVISLSLQDWKNIVSTFEISEAMIKNSY
uniprot
proteins
function
FUNCTION: Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity). {ECO:0000250}.; FUNCTION: Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
44785
uniprot
proteins
protein_family
NSE4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
387
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8N140}. Cytoplasm {ECO:0000250|UniProtKB:Q8N140}. Chromosome, telomere {ECO:0000250}. Note=May shuttle between nucleus and cytoplasm. {ECO:0000250|UniProtKB:Q8N140}.
uniprot
proteins