RPUSD1
entrez
113000
canonical
uniprot
Q9UJJ7
canonical
ensembl
ENSG00000007376
resolver
ensp
ENSP00000007264
resolver
ensp
ENSP00000454616
resolver
ensp
ENSP00000455026
resolver
ensp
ENSP00000455862
resolver
ensp
ENSP00000456692
resolver
ensp
ENSP00000457722
resolver
ensp
ENSP00000588197
resolver
ensp
ENSP00000654868
resolver
enst
ENST00000007264
resolver
enst
ENST00000561734
resolver
enst
ENST00000565809
resolver
enst
ENST00000567114
resolver
enst
ENST00000918138
resolver
genesymbol
RPUSD1
resolver
genesymbol_syn
C16orf40
resolver
genesymbol_syn
RLUCL
resolver
hgnc
HGNC:14173
resolver
uniprot
D3DU66
resolver
uniprot
H3BQN8
resolver
uniprot
H3BUN6
resolver
uniprot_entry
H3BQN8_HUMAN
resolver
uniprot_entry
H3BUN6_HUMAN
resolver
uniprot_entry
RUSD1_HUMAN
resolver
uniprot_sec
D3DU66
resolver
amino_acid_sequence
MEPGSVENLSIVYRSRDFLVVNKHWDVRIDSKAWRETLTLQKQLRYRFPELADPDTCYGFRFCHQLDFSTSGALCVALNKAAAGSAYRCFKERRVTKAYLALLRGHIQESRVTISHAIGRNSTEGRAHTMCIEGSQGCENPKPSLTDLVVLEHGLYAGDPVSKVLLKPLTGRTHQLRVHCSALGHPVVGDLTYGEVSGREDRPFRMMLHAFYLRIPTDTECVEVCTPDPFLPSLDACWSPHTLLQSLDQLVQALRATPDPDPEDRGPRPGSPSALLPGPGRPPPPPTKPPETEAQRGPCLQWLSEWTLEPDS
uniprot
proteins
ec_number
5.4.99.-
uniprot
proteins
function
FUNCTION: Pseudouridylate synthase that catalyzes the conversion of uridine to pseudouridine in cytoplasmic tRNAs. Catalyzes pseudouridylation of pseudouridine-30 and pseudouridine-72 from uracil-30 and uracil-72 within the anticodon stem of cytoplasmic tRNAs. {ECO:0000269|PubMed:41136621, ECO:0000269|PubMed:41698914}.
uniprot
proteins
mass_dalton
34756
uniprot
proteins
mutagenesis
MUTAGEN 67; /note="D->A: Does not rescue the formation of pseudouridine-30 and pseudouridine-72 in cytoplasmic-tRNA in RPUSD1-deficient cells."; /evidence="ECO:0000269|PubMed:41136621
uniprot
proteins
protein_family
Pseudouridine synthase RluA family
uniprot
proteins
pubmed
11157797
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
41136621
uniprot
proteins
pubmed
41698914
uniprot
proteins
sequence_length
312
uniprot
proteins