SELE
entrez
6401
canonical
uniprot
P16581
canonical
ensembl
ENSG00000007908
resolver
ensp
ENSP00000331736
resolver
enst
ENST00000333360
resolver
genesymbol
SELE
resolver
genesymbol_syn
ELAM1
resolver
hgnc
HGNC:10718
resolver
uniprot
A2RRD6
resolver
uniprot
P16111
resolver
uniprot_entry
LYAM2_HUMAN
resolver
uniprot_sec
A2RRD6
resolver
uniprot_sec
P16111
resolver
amino_acid_sequence
MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL
uniprot
proteins
function
FUNCTION: Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. {ECO:0000269|PubMed:1689848, ECO:0000269|PubMed:28011641}.
uniprot
proteins
mass_dalton
66655
uniprot
proteins
mutagenesis
MUTAGEN 109; /note="E->D: Decreased adhesion to cells expressing SELPLG."; /evidence="ECO:0000269|PubMed:28011641
uniprot
proteins
protein_family
Selectin/LECAM family
uniprot
proteins
pubmed
10391210
uniprot
proteins
pubmed
10982036
uniprot
proteins
pubmed
11081633
uniprot
proteins
pubmed
12649084
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
1689848
uniprot
proteins
pubmed
1701274
uniprot
proteins
pubmed
1703529
uniprot
proteins
pubmed
18606703
uniprot
proteins
pubmed
2466335
uniprot
proteins
pubmed
24688092
uniprot
proteins
pubmed
25787250
uniprot
proteins
pubmed
26117840
uniprot
proteins
pubmed
28011641
uniprot
proteins
pubmed
7509040
uniprot
proteins
pubmed
7533025
uniprot
proteins
pubmed
7681016
uniprot
proteins
pubmed
8557254
uniprot
proteins
pubmed
9933738
uniprot
proteins
sequence_length
610
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12649084, ECO:0000269|PubMed:28011641}; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 557..578; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins