OR10J5
entrez
127385
canonical
uniprot
Q8NHC4
canonical
ensembl
ENSG00000184155
resolver
ensp
ENSP00000334441
resolver
enst
ENST00000334857
resolver
genesymbol
OR10J5
resolver
hgnc
HGNC:14993
resolver
uniprot
B9EH35
resolver
uniprot
Q6IFH2
resolver
uniprot_entry
O10J5_HUMAN
resolver
uniprot_sec
B9EH35
resolver
uniprot_sec
Q6IFH2
resolver
amino_acid_sequence
MKRKNFTEVSEFIFLGFSSFGKHQITLFVVFLTVYILTLVANIIIVTIICIDHHLHTPMYFFLSMLASSETVYTLVIVPRMLLSLIFHNQPISLAGCATQMFFFVILATNNCFLLTAMGYDRYVAICRPLRYTVIMSKGLCAQLVCGSFGIGLTMAVLHVTAMFNLPFCGTVVDHFFCDIYPVMKLSCIDTTINEIINYGVSSFVIFVPIGLIFISYVLVISSILQIASAEGRKKTFATCVSHLTVVIVHCGCASIAYLKPKSESSIEKDLVLSVTYTIITPLLNPVVYSLRNKEVKDALCRVVGRNIS
uniprot
proteins
function
FUNCTION: Olfactory receptor. Activated by the synthetic floral odorant, lyral, and by alpha-cedrene, a sesquiterpene constituent of cedarwood oil. Its activation increases intracellular Ca(2+) (PubMed:25791473, PubMed:28842679). Acts as a key regulator of myogenesis through its actions on cell migration and adhesion by activating the Ca(2+)-dependent AKT signal transduction pathway (By similarity). Also acts as a regulator of angiogenesis (PubMed:25791473). Moreover, plays a role in the regulation of lipid accumulation in hepatocytes via the cAMP-PKA pathway (PubMed:28842679). May be involved in sperm chemotaxis and motility (By similarity). {ECO:0000250|UniProtKB:Q62007, ECO:0000269|PubMed:25791473, ECO:0000269|PubMed:28842679}.
uniprot
proteins
mass_dalton
34401
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
14983052
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
25791473
uniprot
proteins
pubmed
28842679
uniprot
proteins
sequence_length
309
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:28842679}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..46; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 140..160; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 197..216; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 237..257; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 271..291; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins