Rps7
entrez
20115
canonical
uniprot
P62082
canonical
ensembl
ENSMUSG00000061477
resolver
ensp
ENSMUSP00000073880
resolver
ensp
ENSMUSP00000152456
resolver
enst
ENSMUST00000074267
resolver
enst
ENSMUST00000221871
resolver
genesymbol
Rps7
resolver
genesymbol_syn
Rps7A
resolver
uniprot
P23821
resolver
uniprot
P24818
resolver
uniprot
Q4FZE6
resolver
uniprot_entry
Q4FZE6_MOUSE
resolver
uniprot_entry
RS7_MOUSE
resolver
uniprot_sec
P23821
resolver
uniprot_sec
P24818
resolver
amino_acid_sequence
MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL
uniprot
proteins
function
FUNCTION: Component of the small ribosomal subunit (PubMed:36517592). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592). Required for rRNA maturation (By similarity). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity). {ECO:0000250|UniProtKB:P62081, ECO:0000269|PubMed:36517592}.
uniprot
proteins
mass_dalton
22127
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by NEK6. {ECO:0000250|UniProtKB:P62081}.; PTM: Ubiquitinated. Deubiquitinated by DESI2, leading to its stabilization. {ECO:0000250|UniProtKB:P62081}.
uniprot
proteins
protein_family
Eukaryotic ribosomal protein eS7 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
36517592
uniprot
proteins
pubmed
9801797
uniprot
proteins
sequence_length
194
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:P62081}. Cytoplasm {ECO:0000250|UniProtKB:P62081}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62081}. Note=Although RPS7 is functional within the cytoplasm, the assembly of ribosomal subunits occurs in the nucleus. RPS7 nuclear import is mediated by IPO5/RanBP5, IPO7/RanBP7, KPNB1/importin-beta or TPNO1/Trn. Colocalizes with NEK6 in the centrosome. {ECO:0000250|UniProtKB:P62081}.
uniprot
proteins