Tor1aip1
entrez
246314
canonical
uniprot
Q5PQX1
canonical
ensembl
ENSRNOG00000003946
resolver
ensp
ENSRNOP00000005280
resolver
ensp
ENSRNOP00000085745
resolver
enst
ENSRNOT00000098741
resolver
genesymbol
Tor1aip1
resolver
uniprot
A0A8I6A2B4
resolver
uniprot
Q62741
resolver
uniprot
Q62754
resolver
uniprot_entry
A0A8I6A2B4_RAT
resolver
uniprot_entry
TOIP1_RAT
resolver
uniprot_sec
Q62741
resolver
uniprot_sec
Q62754
resolver
amino_acid_sequence
MAGERWRAEGLGEGWAIYVTPRAPIREGRRRLATQNGDGSDAPAYETHPSRHGRREVRFSEEPPEVYGDFEPRAAKERSPGERRTPPEKFRSDSAKEEVRESAYNLRSRQRRQRGPQEAEEMKTRRSTRLEQHSQQAQQQLSPATSGRGLRDAQSLSEDRGEDEPSSQPVTSQTVSKKTVRTPETSVMSEDPISNLCRPPLRSPRPDASIVQHINPFEEGETEDDLESSYSDVTIRIRSRDSVESRDEAAVAAGHHPDSLWGLPHSRGDFTAHENQPSLLPTGCQKNPQEWVEQAVRMRTRMAYNNIQKSDFGNQSPSTSRQQAAVQPPDESSVKIKWWLLILVAALAMGIYWFFHTPVVETTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLEKHLNSSLPRPQPAILLLTAAQDAAEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKHEVDQELTDGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEQTLEASLGLKEIEEKVRDFLKVKFTSSDTANSYNHMDPDKLNGLWSRISHLVLPVQPENALKAGSCL
uniprot
proteins
function
FUNCTION: Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
uniprot
proteins
mass_dalton
65649
uniprot
proteins
protein_family
TOR1AIP family
uniprot
proteins
pubmed
14656723
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16128803
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
7721789
uniprot
proteins
sequence_length
583
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus inner membrane {ECO:0000269|PubMed:16128803, ECO:0000269|PubMed:7721789}; Single-pass membrane protein {ECO:0000269|PubMed:16128803, ECO:0000269|PubMed:7721789}.
uniprot
proteins
transmembrane_region
TRANSMEM 340..360; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins