Tmem168
entrez
312135
canonical
uniprot
Q5PQM0
canonical
ensembl
ENSRNOG00000057290
resolver
ensembl
ENSRNOG00055018001
resolver
ensembl
ENSRNOG00060000786
resolver
ensembl
ENSRNOG00065007681
resolver
ensp
ENSRNOP00000069933
resolver
ensp
ENSRNOP00055024559
resolver
ensp
ENSRNOP00060000286
resolver
ensp
ENSRNOP00065008781
resolver
enst
ENSRNOT00000084531
resolver
enst
ENSRNOT00055030510
resolver
enst
ENSRNOT00060000961
resolver
enst
ENSRNOT00065012021
resolver
genesymbol
Tmem168
resolver
uniprot_entry
TM168_RAT
resolver
amino_acid_sequence
MCKSLRYCFSHCLYLAMTRLEEVNREVNMHSSVRYLGYLARFNLLVAICLGLYVRWEKTANSLILVIFILGLFVLGIASILYYYFSMEAASLSLSNLWFGFLLGLLCFLDNSSFKSDVKEETTKYLLLTSIVLRILCALVERLSGYVRHRPTLLTTVEFLELVGFAIASTTMLVERSLSVILLVMALAMLIIDLRMKSFLAIPNLIIFSVLLFFSSLETPQNPIAFACFFICLITDPFLDIYFSGLSVTERWKPFLYRGRICRRLSVVFTGMIELTFFTLSAFKLRDTHLWYFVIPGFSIFGIFWMICHIIFLLTLWGFHTKLNDCHKVYINHRADNNSLDRIMASKGMRHFCLISEQLVFFSLLATAILGAVSWQPTNGIFLSMFLIVLPLESMAHGLFHELGNCLGGTSVGYAIVIPTNFCSPDGQPTLLPPEHVQELNLRSTGMLNAIQRFFAYHMIETYGCDYSTSGLSFDTLHSKLKAFLELRTVDGPRHDTYVLYYSGHTHGSGEWALAGGDILRLDTLLEWWREKNGSFCSRLIIILDSENSTPWVKEVRKINDQYVAVQGAELAKTVDIEEADPPQLGDFTRDWVEYNCNSTNNICWTEKGRTVKAMYGVSKRWSDYTLHLPTGSDVAKHWMLHFPRITYPLVHLANWLCGLNLFWMCKACFRCLKRLKMSWFLPTVLDTGQGFKLVKS
uniprot
proteins
function
FUNCTION: Plays a key role in maintaining the cardiac electrical stability by modulating cell surface expression of SCN5A. May play a role i the modulation of anxiety behavior by regulating GABAergic neuronal system in the nucleus accumbens. {ECO:0000250|UniProtKB:Q91VX9}.
uniprot
proteins
mass_dalton
79772
uniprot
proteins
protein_family
TMEM168 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
697
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250|UniProtKB:Q9H0V1}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..56; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 63..83; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 89..109; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 172..192; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 199..219; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 223..243; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 265..285; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 293..313; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 352..372; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 380..400; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 646..666; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins