Selenow
entrez
20364
canonical
uniprot
P63300
canonical
ensembl
ENSMUSG00000041571
resolver
ensp
ENSMUSP00000038943
resolver
genesymbol
Selenow
resolver
genesymbol_syn
Selw
resolver
genesymbol_syn
Sepw1
resolver
uniprot
O35965
resolver
uniprot
P49904
resolver
uniprot
Q9JIC2
resolver
uniprot_entry
SELW_MOUSE
resolver
uniprot_sec
O35965
resolver
uniprot_sec
P49904
resolver
uniprot_sec
Q9JIC2
resolver
amino_acid_sequence
MALAVRVVYCGAUGYKPKYLQLKEKLEHEFPGCLDICGEGTPQVTGFFEVTVAGKLVHSKKRGDGYVDTESKFRKLVTAIKAALAQCQ
uniprot
proteins
function
FUNCTION: Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency. {ECO:0000269|PubMed:12062442, ECO:0000269|PubMed:16876868, ECO:0000269|PubMed:17503775}.
uniprot
proteins
mass_dalton
9687
uniprot
proteins
mutagenesis
MUTAGEN 10; /note="C->S: Disrupts redox reaction."; MUTAGEN 13; /note="U->C: Increased sensitivity to hydrogen peroxide-induced toxicity."; /evidence="ECO:0000269|PubMed:12062442"; MUTAGEN 13; /note="U->S: Impairs protection against hydrogen peroxide-induced toxicity."; /evidence="ECO:0000269|PubMed:12062442"; MUTAGEN 37; /note="C->S: Impairs protection against hydrogen peroxide-induced toxicity."; /evidence="ECO:0000269|PubMed:12062442
uniprot
proteins
protein_family
SelWTH family
uniprot
proteins
protein_family
Selenoprotein W subfamily
uniprot
proteins
pubmed
12062442
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16876868
uniprot
proteins
pubmed
17503775
uniprot
proteins
pubmed
17928294
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9256076
uniprot
proteins
sequence_length
88
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins