Morn3
entrez
74890
canonical
uniprot
Q8C5T4
canonical
ensembl
ENSMUSG00000029477
resolver
ensp
ENSMUSP00000031437
resolver
ensp
ENSMUSP00000041714
resolver
ensp
ENSMUSP00000349028
resolver
genesymbol
Morn3
resolver
uniprot
Q8VE21
resolver
uniprot
Q9D5H6
resolver
uniprot_entry
MORN3_MOUSE
resolver
uniprot_sec
Q8VE21
resolver
uniprot_sec
Q9D5H6
resolver
amino_acid_sequence
MPVTKCPRKVEPPWKGWDRKAQKNGLRHQVFAVNGDHYVGEWKGNLKHGKGTQVWKKSGAVYEGDWKFGKRDGYGSLSHPDPETGKLRRVYSGWWKGDKKSGYGIQFFGPKEYYEGEWCNNQRSGWGRMYYNNGDIYEGQWQNDKPEGEGMLRLKNGNRYEGIWERGMKNGHGRFFHLDHGQLFEGYWVDNVAKCGTMIDFGRDEAPEPTQFPIPKVEILDPDGVLKEALDKLMKPEEEEG
uniprot
proteins
function
FUNCTION: Assembles a suppression complex (suppresome) by tethering SIRT1 and MDM2 to regulate composite modifications of p53/TP53. Confers both deacetylation-mediated functional inactivation, by SIRT1, and ubiquitination-dependent degradation, by MDM2, of p53/TP53, promoting a proliferative and cell survival behaviors (By similarity). May play a role in the regulation of spermatogenesis (PubMed:25248657). {ECO:0000250|UniProtKB:Q6PF18, ECO:0000269|PubMed:25248657}.
uniprot
proteins
mass_dalton
27881
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
25248657
uniprot
proteins
sequence_length
241
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:25248657}. Note=Localized in the acrosome in germ cells throughout spermiogenesis, it is also present in the manchette of elongating spermatids. {ECO:0000269|PubMed:25248657}.
uniprot
proteins