Tmem59l
entrez
67937
canonical
uniprot
Q7TNI2
canonical
ensembl
ENSMUSG00000035964
resolver
ensp
ENSMUSP00000043659
resolver
ensp
ENSMUSP00000349795
resolver
ensp
ENSMUSP00000349796
resolver
enst
ENSMUST00000045286
resolver
genesymbol
Tmem59l
resolver
genesymbol_syn
Bsmap
resolver
uniprot_entry
TM59L_MOUSE
resolver
amino_acid_sequence
MAAVALPLLLLLASLVTPTPARDPFAPQLGDTQRCQQRCRQHHPGSPPAQPEPEGPSESPNNKAILISACERGCRLFSICRFVAKSSRPNATETECEAACTEAYVKAAEQRACSEGCWGQIPEPETQLEQKDLALDPPRGRLSLRYLFSMLCSDLMSSAQGFLSSSWTYSLQTDNRKVVVFQTQPVAENFAFQGSHLQRVEVTWRRSHPKALELHMDPVGPLDKVRKAKPRVKTSKAKVESEDQQESDFLSCMSRRSGLPRWVLFCCLFLSILIMLWLSCCTLVTTPGQHLKFQPLTAEQHKGLLVESDWPLYPPLPPPAYEDSTPPYKLKLDLTTL
uniprot
proteins
function
FUNCTION: Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37661
uniprot
proteins
protein_family
TMEM59 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 263..283; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins