Pex13
entrez
72129
canonical
uniprot
Q9D0K1
canonical
ensembl
ENSMUSG00000020283
resolver
ensp
ENSMUSP00000020523
resolver
enst
ENSMUST00000020523
resolver
genesymbol
Pex13
resolver
uniprot
Q3U5T1
resolver
uniprot
Q8CCJ5
resolver
uniprot
Q8CCW5
resolver
uniprot
Q99MM2
resolver
uniprot
Q9EPK1
resolver
uniprot_entry
PEX13_MOUSE
resolver
uniprot_sec
Q3U5T1
resolver
uniprot_sec
Q8CCJ5
resolver
uniprot_sec
Q8CCW5
resolver
uniprot_sec
Q99MM2
resolver
uniprot_sec
Q9EPK1
resolver
amino_acid_sequence
MASQPPPPPKPWESRRIPGAGPGPGSGPGPTYQSADLGPTLLTRPGQPTLTRVPPPILPRPSQQTGSNNVNTFRPAYSSFSSGYGAYGNSFYGSYSPYSYGYNGLGFNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQWMMGLRRGSENEDLWAESEGTVACLSAEDQATNSAKSWPIFLFFAVILGGPYLIWKLLSTHNDEVTDNTNWASGEDDHVVARAEYDFVAVSDEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRRGRKTIESSTMLKQQQSFTNPTLIKGVTTTNPLDEQEAAFESVFVETNKVSSAPDSTGKNGDKQDL
uniprot
proteins
function
FUNCTION: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix. Involved in the import of PTS1- and PTS2-type containing proteins (By similarity). {ECO:0000250|UniProtKB:P80667, ECO:0000250|UniProtKB:Q92968}.
uniprot
proteins
mass_dalton
44610
uniprot
proteins
protein_family
Peroxin-13 family
uniprot
proteins
pubmed
11829486
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
405
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250|UniProtKB:Q92968}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 137..157; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 177..194; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 236..256; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins