Slk
entrez
20874
canonical
uniprot
O54988
canonical
ensembl
ENSMUSG00000025060
resolver
ensp
ENSMUSP00000026043
resolver
ensp
ENSMUSP00000049977
resolver
genesymbol
Slk
resolver
genesymbol_syn
Kiaa0204
resolver
genesymbol_syn
Stk2
resolver
uniprot
A2RRK3
resolver
uniprot
A2RRK4
resolver
uniprot
Q80U65
resolver
uniprot
Q8CAU2
resolver
uniprot
Q8CDW2
resolver
uniprot
Q9WU41
resolver
uniprot_entry
A2RRK3_MOUSE
resolver
uniprot_entry
SLK_MOUSE
resolver
uniprot_sec
A2RRK4
resolver
uniprot_sec
Q80U65
resolver
uniprot_sec
Q8CAU2
resolver
uniprot_sec
Q8CDW2
resolver
uniprot_sec
Q9WU41
resolver
amino_acid_sequence
MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWEIIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFVTVDSNKPVRELIAEAKAEVTEEVEDGKEEDEEEEAENALPIPANKRASSDLSIASSEEDKLSQNACILESVSERTEQSTSEDKFSNKILNEKPTTDGPEKAVDEHASDVNLETGAELNDQTVGIHENGREKKRPKLENLPDTQDQQTVDVNSVSEENENNRVTLETNTDCLKPEEDRNKENQETLESKLIQSEEINDTHIQTMDLVSQETGEKEADFQAVDNEVGLTKEETQEKLGKDGTAQKVITSDRSSEVGTDEALDDTQKAAELSKAAQSGEGDEALAPTQTLAEKPTEGPEAGGAEEEPPGGERVEDKQPEQQPAVCEAEGQLTSTSETTRATLEQPETDEVEQVSESNSIEELERLVVTGAEARALGSEGEAAATEVDLERKENAQKVPVKAESQAPAASQPSEPHPVLIPSININSETTENKEEMGALPKPETILPPEPEHEKGNDTDSGTGSTVENSSGDLNLSISSFLSKAKDSGSVSLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRLLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMLSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNVLKNRKKEVMNEVEKAPRELRRELTKRRKEELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDREKIKQFAAQEEKRQKNERMAQHQKHESQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSAQSRISKFYPIPTLHSTGS
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Mediates apoptosis and actin stress fiber dissolution. {ECO:0000269|PubMed:10611247}.
uniprot
proteins
mass_dalton
141457
uniprot
proteins
mutagenesis
MUTAGEN 436; /note="D->N: No change in caspase-3-induced cleavage product."; /evidence="ECO:0000269|PubMed:10611247
uniprot
proteins
post_translational_modification
PTM: Proteolytically cleaved by caspase-3. {ECO:0000269|PubMed:10611247}.; PTM: Autophosphorylated. {ECO:0000269|PubMed:9808774}.
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
STE Ser/Thr protein kinase family
uniprot
proteins
protein_family
STE20 subfamily
uniprot
proteins
pubmed
10611247
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8346215
uniprot
proteins
pubmed
9808774
uniprot
proteins
sequence_length
1233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10611247, ECO:0000269|PubMed:9808774}.
uniprot
proteins