Chrna1
entrez
11435
canonical
uniprot
P04756
canonical
ensembl
ENSMUSG00000027107
resolver
ensp
ENSMUSP00000028515
resolver
enst
ENSMUST00000028515
resolver
genesymbol
Chrna1
resolver
genesymbol_syn
Acra
resolver
uniprot
Q05A24
resolver
uniprot_entry
ACHA_MOUSE
resolver
uniprot_entry
Q05A24_MOUSE
resolver
amino_acid_sequence
MELSTVLLLLGLCSAGLVLGSEHETRLVAKLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPTTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTSLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHIMPEWVRKVFIDTIPNIMFFSTMKRPSRDKQEKRIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGVKYIAETMKSDQESNNAAEEWKYVAMVMDHILLGVFMLVCLIGTLAVFAGRLIELHQQG
uniprot
proteins
function
FUNCTION: Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. {ECO:0000250|UniProtKB:P02708}.
uniprot
proteins
mass_dalton
51939
uniprot
proteins
protein_family
Acetylcholine receptor (TC 1.A.9.1) subfamily
uniprot
proteins
protein_family
Alpha-1/CHRNA1 sub-subfamily
uniprot
proteins
protein_family
Ligand-gated ion channel (TC 1.A.9) family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17643119
uniprot
proteins
pubmed
2993547
uniprot
proteins
pubmed
3755237
uniprot
proteins
sequence_length
457
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic cell membrane {ECO:0000250|UniProtKB:P02708}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P02708}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 231..255; /note="Helical"; TRANSMEM 263..281; /note="Helical"; TRANSMEM 297..316; /note="Helical"; TRANSMEM 429..447; /note="Helical
uniprot
proteins