Guk1
entrez
14923
canonical
uniprot
Q64520
canonical
ensembl
ENSMUSG00000020444
resolver
ensp
ENSMUSP00000127566
resolver
ensp
ENSMUSP00000130214
resolver
ensp
ENSMUSP00000134236
resolver
ensp
ENSMUSP00000191638
resolver
enst
ENSMUST00000170895
resolver
genesymbol
Guk1
resolver
genesymbol_syn
Gmk
resolver
uniprot
E9Q7K1
resolver
uniprot
Q564F2
resolver
uniprot
Q564G0
resolver
uniprot_entry
E9Q7K1_MOUSE
resolver
uniprot_entry
KGUA_MOUSE
resolver
uniprot_sec
Q564F2
resolver
uniprot_sec
Q564G0
resolver
amino_acid_sequence
MAGPRPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHTTRNPRPGEEDGKDYYFVTREMMQRDIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCPIYIFVQPPSLDVLEQRLRLRNTETEESLAKRLAAARTDMESSKEPGLFDLVIINDDLDKAYATLKQALSEEIKKAQGTGHA
uniprot
proteins
ec_number
2.7.4.8
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP) (PubMed:8663313). Involved in the cGMP metabolism in photoreceptors (By similarity). {ECO:0000250|UniProtKB:P46195, ECO:0000269|PubMed:8663313}.
uniprot
proteins
mass_dalton
21918
uniprot
proteins
protein_family
Guanylate kinase family
uniprot
proteins
pubmed
12036965
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29515371
uniprot
proteins
pubmed
8663313
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Photoreceptor inner segment {ECO:0000269|PubMed:29515371}. Cytoplasm, cytosol {ECO:0000269|PubMed:29515371}. Note=Colocalizes with RD3 in photoreceptor inner segments and to a lesser extent in the outer plexiform layer. {ECO:0000269|PubMed:29515371}.; SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion {ECO:0000250|UniProtKB:Q16774}.
uniprot
proteins