SYT3
entrez
84258
canonical
uniprot
Q9BQG1
canonical
ensembl
ENSG00000213023
resolver
ensp
ENSP00000340914
resolver
ensp
ENSP00000468982
resolver
ensp
ENSP00000469398
resolver
ensp
ENSP00000567722
resolver
ensp
ENSP00000567723
resolver
ensp
ENSP00000567724
resolver
ensp
ENSP00000567725
resolver
ensp
ENSP00000606962
resolver
ensp
ENSP00000606963
resolver
ensp
ENSP00000606964
resolver
ensp
ENSP00000606965
resolver
ensp
ENSP00000606966
resolver
ensp
ENSP00000634250
resolver
enst
ENST00000338916
resolver
enst
ENST00000593901
resolver
enst
ENST00000600079
resolver
enst
ENST00000897663
resolver
enst
ENST00000897664
resolver
enst
ENST00000897665
resolver
enst
ENST00000897666
resolver
enst
ENST00000936903
resolver
enst
ENST00000936904
resolver
enst
ENST00000936905
resolver
enst
ENST00000936906
resolver
enst
ENST00000936907
resolver
enst
ENST00000964191
resolver
genesymbol
SYT3
resolver
hgnc
HGNC:11511
resolver
uniprot
Q8N5Z1
resolver
uniprot
Q8N640
resolver
uniprot_entry
SYT3_HUMAN
resolver
uniprot_sec
Q8N5Z1
resolver
uniprot_sec
Q8N640
resolver
amino_acid_sequence
MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNDRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLGPGVGLAGLVGGGGHHLAAGLGGHPLLGGPHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELPSEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTSQPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE
uniprot
proteins
function
FUNCTION: Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003). {ECO:0000250|UniProtKB:P40748, ECO:0000269|PubMed:23999003}.
uniprot
proteins
mass_dalton
63304
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
23999003
uniprot
proteins
sequence_length
590
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P40748}; Single-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins