MPV17L
entrez
255027
canonical
uniprot
Q2QL34
canonical
ensembl
ENSG00000156968
resolver
ensembl
ENSG00000275543
resolver
ensp
ENSP00000287594
resolver
ensp
ENSP00000379669
resolver
genesymbol
MPV17L
resolver
hgnc
HGNC:26827
resolver
uniprot
B4DDY1
resolver
uniprot
Q6P7T6
resolver
uniprot
Q8N8E9
resolver
uniprot_entry
MP17L_HUMAN
resolver
uniprot_sec
B4DDY1
resolver
uniprot_sec
Q6P7T6
resolver
uniprot_sec
Q8N8E9
resolver
amino_acid_sequence
MAGWWPALSRAARRHPWPTNVLLYGSLVSAGDALQQRLQGREANWRQTRRVATLVVTFHANFNYVWLRLLERALPGRAPHALLAKLLCDQVVGAPIAVSAFYVGMSILQGKDDIFLDLKQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFICFSQQSGDGTFKSAFTILYTKGTSATEGYPKK
uniprot
proteins
function
FUNCTION: [Isoform 1]: Participates in reactive oxygen species metabolism by up- or down-regulation of the genes of antioxidant enzymes (PubMed:16631601). Protective against the mitochondrial apoptotic cascade (PubMed:22306510). {ECO:0000269|PubMed:16631601, ECO:0000269|PubMed:22306510}.
uniprot
proteins
mass_dalton
22116
uniprot
proteins
protein_family
Peroxisomal membrane protein PXMP2/4 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16631601
uniprot
proteins
pubmed
22306510
uniprot
proteins
sequence_length
196
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Peroxisome membrane {ECO:0000269|PubMed:16631601}; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 17..34; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 51..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 91..108; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 151..167; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins