RPL10
entrez
6134
canonical
uniprot
P27635
canonical
ensembl
ENSG00000147403
resolver
ensp
ENSP00000341730
resolver
ensp
ENSP00000358832
resolver
ensp
ENSP00000388600
resolver
ensp
ENSP00000395025
resolver
ensp
ENSP00000560632
resolver
ensp
ENSP00000560636
resolver
ensp
ENSP00000618769
resolver
ensp
ENSP00000699953
resolver
enst
ENST00000344746
resolver
enst
ENST00000369817
resolver
enst
ENST00000890573
resolver
enst
ENST00000948710
resolver
genesymbol
RPL10
resolver
genesymbol_syn
DXS648E
resolver
genesymbol_syn
QM
resolver
hgnc
HGNC:10298
resolver
uniprot
A3KQT0
resolver
uniprot
D3DWW6
resolver
uniprot
Q16470
resolver
uniprot
Q2HXT7
resolver
uniprot
Q53FH7
resolver
uniprot
Q6FGN8
resolver
uniprot
Q8TDA5
resolver
uniprot
X5D2T3
resolver
uniprot_entry
RL10_HUMAN
resolver
uniprot_entry
X5D2T3_HUMAN
resolver
uniprot_sec
A3KQT0
resolver
uniprot_sec
D3DWW6
resolver
uniprot_sec
Q16470
resolver
uniprot_sec
Q2HXT7
resolver
uniprot_sec
Q53FH7
resolver
uniprot_sec
Q6FGN8
resolver
uniprot_sec
Q8TDA5
resolver
amino_acid_sequence
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPSRGPLDKWRALHS
uniprot
proteins
disease_involvement
DISEASE: Autism, X-linked 5 (AUTSX5) [MIM:300847]: A complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate intellectual disability. {ECO:0000269|PubMed:16940977, ECO:0000269|PubMed:21567917}. Note=Disease susceptibility is associated with variants affecting the gene represented in this entry. RPL10 is involved in autism only in rare cases. Two hypomorphic variants affecting the translation process have been found in families with autism spectrum disorders, suggesting that aberrant translation may play a role in disease mechanisms.; DISEASE: Intellectual developmental disorder, X-linked, syndromic 35 (MRXS35) [MIM:300998]: A syndrome characterized by intellectual deficit, delayed psychomotor development, poor speech, and dysmorphic features. {ECO:0000269|PubMed:25316788, ECO:0000269|PubMed:25846674, ECO:0000269|PubMed:26290468}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Component of the large ribosomal subunit (PubMed:26290468). Plays a role in the formation of actively translating ribosomes (PubMed:26290468). May play a role in the embryonic brain development (PubMed:25316788). {ECO:0000269|PubMed:25316788, ECO:0000269|PubMed:26290468, ECO:0000305|PubMed:12962325}.
uniprot
proteins
mass_dalton
24577
uniprot
proteins
post_translational_modification
PTM: Citrullinated by PADI4. {ECO:0000250|UniProtKB:Q6ZWV3}.; PTM: Ufmylated by UFL1. {ECO:0000250|UniProtKB:Q6ZWV3}.
uniprot
proteins
protein_family
Universal ribosomal protein uL16 family
uniprot
proteins
pubmed
12138090
uniprot
proteins
pubmed
12962325
uniprot
proteins
pubmed
1303197
uniprot
proteins
pubmed
1339145
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
1534224
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
1658743
uniprot
proteins
pubmed
16627977
uniprot
proteins
pubmed
16940977
uniprot
proteins
pubmed
18258260
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21567917
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24524803
uniprot
proteins
pubmed
25316788
uniprot
proteins
pubmed
25846674
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26290468
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
8733135
uniprot
proteins
pubmed
9582194
uniprot
proteins
sequence_length
214
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6ZWV3}.
uniprot
proteins