HSD17B11
entrez
51170
canonical
uniprot
Q8NBQ5
canonical
ensembl
ENSG00000198189
resolver
ensp
ENSP00000351035
resolver
enst
ENST00000358290
resolver
genesymbol
HSD17B11
resolver
genesymbol_syn
DHRS8
resolver
genesymbol_syn
PAN1B
resolver
genesymbol_syn
SDR16C2
resolver
hgnc
HGNC:22960
resolver
uniprot
Q96HF6
resolver
uniprot
Q9UKU4
resolver
uniprot_entry
DHB11_HUMAN
resolver
uniprot_sec
Q96HF6
resolver
uniprot_sec
Q9UKU4
resolver
amino_acid_sequence
MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ
uniprot
proteins
ec_number
1.1.1.62
uniprot
proteins
function
FUNCTION: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
uniprot
proteins
mass_dalton
32964
uniprot
proteins
protein_family
17-beta-HSD 3 subfamily
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
10800688
uniprot
proteins
pubmed
11165019
uniprot
proteins
pubmed
12697717
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14996095
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9888557
uniprot
proteins
sequence_length
300
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9EQ06}. Lipid droplet {ECO:0000250|UniProtKB:Q9EQ06}. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation. {ECO:0000250|UniProtKB:Q9EQ06}.
uniprot
proteins