Ltbr
entrez
17000
canonical
uniprot
P50284
canonical
ensembl
ENSMUSG00000030339
resolver
ensp
ENSMUSP00000032489
resolver
ensp
ENSMUSP00000174951
resolver
enst
ENSMUST00000032489
resolver
genesymbol
Ltbr
resolver
genesymbol_syn
Tnfcr
resolver
genesymbol_syn
Tnfrsf3
resolver
uniprot
B2RRV3
resolver
uniprot_entry
B2RRV3_MOUSE
resolver
uniprot_entry
TNR3_MOUSE
resolver
amino_acid_sequence
MRLPRASSPCGLAWGPLLLGLSGLLVASQPQLVPPYRIENQTCWDQDKEYYEPMHDVCCSRCPPGEFVFAVCSRSQDTVCKTCPHNSYNEHWNHLSTCQLCRPCDIVLGFEEVAPCTSDRKAECRCQPGMSCVYLDNECVHCEEERLVLCQPGTEAEVTDEIMDTDVNCVPCKPGHFQNTSSPRARCQPHTRCEIQGLVEAAPGTSYSDTICKNPPEPGAMLLLAILLSLVLFLLFTTVLACAWMRHPSLCRKLGTLLKRHPEGEESPPCPAPRADPHFPDLAEPLLPMSGDLSPSPAGPPTAPSLEEVVLQQQSPLVQARELEAEPGEHGQVAHGANGIHVTGGSVTVTGNIYIYNGPVLGGTRGPGDPPAPPEPPYPTPEEGAPGPSELSTPYQEDGKAWHLAETETLGCQDL
uniprot
proteins
function
FUNCTION: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling upon stimulation with lymphotoxin. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. {ECO:0000250, ECO:0000250|UniProtKB:P36941}.; FUNCTION: (Microbial infection) Plays a role in host defense against Zika virus infection. {ECO:0000269|PubMed:29507355}.
uniprot
proteins
mass_dalton
44956
uniprot
proteins
pubmed
29507355
uniprot
proteins
pubmed
7594541
uniprot
proteins
pubmed
8586432
uniprot
proteins
pubmed
8663299
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins