Enpp6
entrez
306460
canonical
uniprot
B0BND0
canonical
ensembl
ENSRNOG00000009660
resolver
ensembl
ENSRNOG00055011594
resolver
ensembl
ENSRNOG00060008654
resolver
ensembl
ENSRNOG00065015085
resolver
ensp
ENSRNOP00000080476
resolver
ensp
ENSRNOP00055015877
resolver
ensp
ENSRNOP00060011130
resolver
ensp
ENSRNOP00065019557
resolver
enst
ENSRNOT00000111159
resolver
enst
ENSRNOT00055019686
resolver
enst
ENSRNOT00060014467
resolver
enst
ENSRNOT00065024987
resolver
genesymbol
Enpp6
resolver
uniprot_entry
ENPP6_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by EDTA and EGTA in vitro. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MAGKLWTFLLLFGFSWVWPASAHRKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKNVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALKAVDTVLKYMTQWIQERGLQNDLNVILFSDHGMTDIFWMDKVIELSKYISLDDLQQVKDQGPVVSLWPVPEKHSEIYHKLRTVEHMTVYEKEAIPNRFYYKKGKFVSPLTLVADEGWFIAESREALPFWMNSTGKREGWQHGWHGYDNELMDMRGIFLAFGPDFKSNFRAAPIRSVDVYNIMCNVVGITPLPNNGSWSRVVCMLKSQTSSSPSIPPNSCALVLILLLYFV
uniprot
proteins
ec_number
3.1.4.-
uniprot
proteins
ec_number
3.1.4.38
uniprot
proteins
function
FUNCTION: Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids. {ECO:0000250|UniProtKB:Q8BGN3}.
uniprot
proteins
mass_dalton
50701
uniprot
proteins
protein_family
Nucleotide pyrophosphatase/phosphodiesterase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
24090084
uniprot
proteins
sequence_length
440
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
uniprot
proteins