Ano7
entrez
404545
canonical
uniprot
Q14AT5
canonical
ensembl
ENSMUSG00000034107
resolver
ensp
ENSMUSP00000050495
resolver
ensp
ENSMUSP00000140438
resolver
genesymbol
Ano7
resolver
genesymbol_syn
Ngep
resolver
genesymbol_syn
Tmem16g
resolver
uniprot
Q6IFT5
resolver
uniprot_entry
ANO7_MOUSE
resolver
uniprot_sec
Q6IFT5
resolver
amino_acid_sequence
MLRGQAREEDSVVLIDMASPEAGNGCSYGSTAQASEAGKQQVAPSRVGSSAKPPIDFVLVWEEDLRNQENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFSAVPESSQVLGLIQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCSDCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRSDNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFSRGKKAGTGTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQALAENEALLGATGVKDDQPPSSEPSLGLPA
uniprot
proteins
function
FUNCTION: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (PubMed:23532839). Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:23532839). May play a role in cell-cell interactions (By similarity). {ECO:0000250|UniProtKB:Q6IWH7, ECO:0000269|PubMed:23532839}.
uniprot
proteins
mass_dalton
97128
uniprot
proteins
protein_family
Anoctamin family
uniprot
proteins
pubmed
14981236
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20056604
uniprot
proteins
pubmed
22302790
uniprot
proteins
pubmed
23532839
uniprot
proteins
sequence_length
859
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q6IWH7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q6IWH7}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q6IWH7}. Note=Concentrates at sites of cell-cell contact. Shows an intracellular localization. {ECO:0000250|UniProtKB:Q6IWH7}.
uniprot
proteins
transmembrane_region
TRANSMEM 298..318; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 363..383; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 442..462; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 493..513; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 531..551; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 652..672; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 701..721; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 781..801; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins