Rpl23a
entrez
268449
canonical
uniprot
P62751
canonical
ensembl
ENSMUSG00000058546
resolver
ensp
ENSMUSP00000099541
resolver
enst
ENSMUST00000102483
resolver
genesymbol
Rpl23a
resolver
uniprot
P29316
resolver
uniprot
P39024
resolver
uniprot
Q5M9M5
resolver
uniprot
Q92774
resolver
uniprot_entry
Q5M9M5_MOUSE
resolver
uniprot_entry
RL23A_MOUSE
resolver
uniprot_sec
P29316
resolver
uniprot_sec
P39024
resolver
uniprot_sec
Q92774
resolver
amino_acid_sequence
MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII
uniprot
proteins
function
FUNCTION: Component of the large ribosomal subunit (PubMed:36517592). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592). Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity). {ECO:0000250|UniProtKB:P62750, ECO:0000269|PubMed:36517592}.
uniprot
proteins
mass_dalton
17695
uniprot
proteins
post_translational_modification
PTM: N-terminus is methylated by METTL11A/NTM1. {ECO:0000269|PubMed:20668449}.; PTM: Citrullinated by PADI4. {ECO:0000269|PubMed:24463520}.
uniprot
proteins
protein_family
Universal ribosomal protein uL23 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20668449
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24463520
uniprot
proteins
pubmed
36517592
uniprot
proteins
sequence_length
156
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:36517592}. Nucleus {ECO:0000250|UniProtKB:P62750}. Note=Although RPL23A is functional within the cytoplasm, the assembly of ribosomal subunits occurs in the nucleus. RPL23A nuclear import is mediated by IPO5/RanBP5, IPO7/RanBP7, KPNB1/importin-beta or TPNO1/Trn. {ECO:0000250|UniProtKB:P62750}.
uniprot
proteins