Atp5mc3
entrez
228033
canonical
uniprot
P56384
canonical
ensembl
ENSMUSG00000018770
resolver
ensp
ENSMUSP00000018914
resolver
ensp
ENSMUSP00000107627
resolver
ensp
ENSMUSP00000330247
resolver
enst
ENSMUST00000018914
resolver
enst
ENSMUST00000111996
resolver
genesymbol
Atp5mc3
resolver
genesymbol_syn
Atp5g3
resolver
uniprot
Q14BC2
resolver
uniprot_entry
AT5G3_MOUSE
resolver
uniprot_entry
Q14BC2_MOUSE
resolver
amino_acid_sequence
MFACAKLARTPALIRAGSRVAYRPISASVLSRPETRTGEGSTVFNGAQNGVCQLIRREFQTSVISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
uniprot
proteins
disease_involvement
DISEASE: Note=This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease).
uniprot
proteins
function
FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
uniprot
proteins
mass_dalton
14745
uniprot
proteins
post_translational_modification
PTM: Trimethylated by ATPSCKMT at Lys-109. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. {ECO:0000269|PubMed:30530489}.
uniprot
proteins
protein_family
ATPase C chain family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
30530489
uniprot
proteins
sequence_length
141
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins