Plcb4
entrez
25031
canonical
uniprot
Q9QW07
canonical
ensembl
ENSRNOG00000033119
resolver
ensp
ENSRNOP00000045972
resolver
ensp
ENSRNOP00000048553
resolver
ensp
ENSRNOP00000087693
resolver
enst
ENSRNOT00000042853
resolver
enst
ENSRNOT00000045393
resolver
genesymbol
Plcb4
resolver
uniprot
D4A8C5
resolver
uniprot
F1LNK2
resolver
uniprot
O88356
resolver
uniprot
Q9Z0G6
resolver
uniprot_entry
D4A8C5_RAT
resolver
uniprot_entry
F1LNK2_RAT
resolver
uniprot_entry
PLCB4_RAT
resolver
uniprot_sec
O88356
resolver
uniprot_sec
Q9Z0G6
resolver
amino_acid_sequence
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRLAAIPKDPKILAALESVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEITKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTSGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYQMSKYCEDLFGDLLLKQALESHPLEPGRLLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSMMEAGESAAPASILEDDNEEEIESADQEEEAHPEYKFGNELSADDFSHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQLRAMGIETSDIADVPSDTSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEIKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV
uniprot
proteins
ec_number
3.1.4.11
uniprot
proteins
function
FUNCTION: Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G protein-coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development (By similarity). {ECO:0000250|UniProtKB:Q07722, ECO:0000250|UniProtKB:Q15147}.
uniprot
proteins
mass_dalton
134497
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
7688223
uniprot
proteins
pubmed
8407970
uniprot
proteins
pubmed
9931434
uniprot
proteins
sequence_length
1175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q15147}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q15147}; Cytoplasmic side {ECO:0000250|UniProtKB:Q15147}.
uniprot
proteins