ENO2
entrez
2026
canonical
uniprot
P09104
canonical
ensembl
ENSG00000111674
resolver
ensp
ENSP00000229277
resolver
genesymbol
ENO2
resolver
genesymbol_syn
HEL-S-279
resolver
hgnc
HGNC:3353
resolver
uniprot
B7Z2X9
resolver
uniprot
Q6FHV6
resolver
uniprot
Q96J33
resolver
uniprot_entry
ENOG_HUMAN
resolver
uniprot_entry
Q6FHV6_HUMAN
resolver
uniprot_sec
B7Z2X9
resolver
uniprot_sec
Q96J33
resolver
amino_acid_sequence
MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL
uniprot
proteins
ec_number
4.2.1.11
uniprot
proteins
function
FUNCTION: Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis (By similarity). Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). {ECO:0000250|UniProtKB:P06733, ECO:0000250|UniProtKB:P07323}.
uniprot
proteins
mass_dalton
47269
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
uniprot
proteins
protein_family
Enolase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15289101
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
2045099
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2792767
uniprot
proteins
pubmed
29775581
uniprot
proteins
pubmed
3208766
uniprot
proteins
pubmed
3385803
uniprot
proteins
pubmed
36459650
uniprot
proteins
pubmed
3653393
uniprot
proteins
pubmed
9074930
uniprot
proteins
sequence_length
434
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. {ECO:0000250}.
uniprot
proteins