E2f5
entrez
13559
canonical
uniprot
Q61502
canonical
ensembl
ENSMUSG00000027552
resolver
ensp
ENSMUSP00000029069
resolver
enst
ENSMUST00000029069
resolver
genesymbol
E2f5
resolver
uniprot
Q99LK0
resolver
uniprot_entry
E2F5_MOUSE
resolver
uniprot_sec
Q99LK0
resolver
amino_acid_sequence
MAAAEPTSSAQPTPQAQAQPPPHGAPSSQPSAALAGGSSRHEKSLGLLTTKFVSLLQEAQDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRCLKAEIEDLELKERELDQQKLWLQQSIKNVMEDSINNRFSYVTHEDICNCFHGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFPVPPPDDLTQPSSQSSTSVTPQKSTMAAQNLPEQHVSERSQTFQQTPAAEVSSGSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
uniprot
proteins
function
FUNCTION: Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis. {ECO:0000250|UniProtKB:Q6DE14}.
uniprot
proteins
mass_dalton
36555
uniprot
proteins
protein_family
E2F/DP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
7542760
uniprot
proteins
pubmed
9149906
uniprot
proteins
pubmed
9376316
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins