STK17A
entrez
9263
canonical
uniprot
Q9UEE5
canonical
ensembl
ENSG00000164543
resolver
ensp
ENSP00000319192
resolver
ensp
ENSP00000497301
resolver
enst
ENST00000319357
resolver
enst
ENST00000648544
resolver
genesymbol
STK17A
resolver
genesymbol_syn
DRAK1
resolver
hgnc
HGNC:11395
resolver
uniprot
A4D1V6
resolver
uniprot
Q8IVC8
resolver
uniprot_entry
ST17A_HUMAN
resolver
uniprot_sec
A4D1V6
resolver
uniprot_sec
Q8IVC8
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by thiazolidinedione-type compounds: inhibited by furan- and pyridone- thiazolidinediones. {ECO:0000269|PubMed:21802008}.
uniprot
proteins
amino_acid_sequence
MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species. {ECO:0000269|PubMed:21489989, ECO:0000269|PubMed:9786912}.
uniprot
proteins
mass_dalton
46558
uniprot
proteins
mutagenesis
MUTAGEN 90; /note="K->A: Loss of activity and of apoptotic function."; /evidence="ECO:0000269|PubMed:9786912
uniprot
proteins
post_translational_modification
PTM: Autophosphorylated.
uniprot
proteins
protein_family
CAMK Ser/Thr protein kinase family
uniprot
proteins
protein_family
DAP kinase subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15940259
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
21489989
uniprot
proteins
pubmed
21802008
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
9786912
uniprot
proteins
sequence_length
414
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9786912}.
uniprot
proteins