RAB11FIP1
entrez
80223
canonical
uniprot
Q6WKZ4
canonical
ensembl
ENSG00000156675
resolver
ensp
ENSP00000287263
resolver
ensp
ENSP00000331342
resolver
genesymbol
RAB11FIP1
resolver
genesymbol_syn
RCP
resolver
hgnc
HGNC:30265
resolver
uniprot
J3KNP0
resolver
uniprot
Q307T1
resolver
uniprot
Q6AZK4
resolver
uniprot
Q6WKZ2
resolver
uniprot
Q6WKZ6
resolver
uniprot
Q86YV4
resolver
uniprot
Q8TDL1
resolver
uniprot
Q9H642
resolver
uniprot_entry
RFIP1_HUMAN
resolver
uniprot_sec
J3KNP0
resolver
uniprot_sec
Q307T1
resolver
uniprot_sec
Q6AZK4
resolver
uniprot_sec
Q6WKZ2
resolver
uniprot_sec
Q6WKZ6
resolver
uniprot_sec
Q86YV4
resolver
uniprot_sec
Q8TDL1
resolver
uniprot_sec
Q9H642
resolver
amino_acid_sequence
MSLMVSAGRGLGAVWSPTHVQVTVLQARGLRAKGPGGTSDAYAVIQVGKEKYATSVSERSLGAPVWREEATFELPSLLSSGPAAAATLQLTVLHRALLGLDKFLGRAEVDLRDLHRDQGRRKTQWYKLKSKPGKKDKERGEIEVDIQFMRNNMTASMFDLSMKDKSRNPFGKLKDKIKGKNKDSGSDTASAIIPSTTPSVDSDDESVVKDKKKKSKIKTLLSKSNLQKTPLSQSMSVLPTSKPEKVLLRPGDFQSQWDEDDNEDESSSASDVMSHKRTASTDLKQLNQVNFTLPKKEGLSFLGGLRSKNDVLSRSNVCINGNHVYLEQPEAKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSLKSMTLPSYRPAPLVSGDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAKGSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDVQITEPEAEPESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLPPLPSSSGQASVPSELGHGADTQSSESPSVFSSLSSPIAAPISTSTPIESWPLVDRGQAKSEGPPLLPKAELQTESLTPVPNSGSSALGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRFPCKKQDYSPSSGEAQEVPFALSLSSDGAVSPVGELAAGGDRDLESQAGSLVESKARDAAEEVAPPLPMGASVPSIDSMMRKLEEMGLNLRKDQKKTKKRVSFSEQLFTEEAVAGAALLVEGHSSCPQELNPAWSVAGNASDGEPPESPHAEDSERESVTTPGPATCGAPASPADHLLLPSQEESFSEVPMSEASSAKDTPLFRMEGEDALVTQYQSKASDHEGLLSDPLSDLQLVSDFKSPIMADLNLSLPSIPEVASDDERIDQVEDDGDQVEDDGETAKSSTLDIGALSLGLVVPCPERGKGPSGEADRLVLGEGLCDFRLQAPQASVTAPSEQTTEFGIHKPHLGKSSSLDKQLPGPSGGEEEKPMGNGSPSPPPGTSLDNPVPSPSPSEIFPVTHSFPSSAHSDTHHTSTAESQKKATAEGSAGRVENFGKRKPLLQAWVSPSETHPVSAQPGAGTGSAKHRLHPVKPMNAMATKVANCSLGTATIISENLNNEVMMKKYSPSDPAFAYAQLTHDELIQLVLKQKETISKKEFQVRELEDYIDNLLVRVMEETPNILRIPTQVGKKAGKM
uniprot
proteins
function
FUNCTION: A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. Interaction with RAB14 may function in the process of neurite formation (PubMed:26032412). {ECO:0000269|PubMed:11786538, ECO:0000269|PubMed:15181150, ECO:0000269|PubMed:15355514, ECO:0000269|PubMed:16920206, ECO:0000269|PubMed:26032412}.
uniprot
proteins
mass_dalton
137167
uniprot
proteins
mutagenesis
MUTAGEN 1254; /note="Y->F: Does not abolish the interaction with RAB11A, homooligomerization and subcellular location. Reduces the interaction with RAB4A."; /evidence="ECO:0000269|PubMed:15280022"; MUTAGEN 1255; /note="I->E: Abolishes the interaction with RAB11A, RAB4A and RAB14, homooligomerization and subcellular location."; /evidence="ECO:0000269|PubMed:15280022, ECO:0000269|PubMed:26032412"; MUTAGEN 1256; /note="D->N: Does not abolish the interaction with RAB11A, homooligomerization and subcellular location. Reduces the interaction with RAB4A."; /evidence="ECO:0000269|PubMed:15280022
uniprot
proteins
pubmed
11495908
uniprot
proteins
pubmed
11786538
uniprot
proteins
pubmed
11944901
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15181150
uniprot
proteins
pubmed
15280022
uniprot
proteins
pubmed
15355514
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
16920206
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
26032412
uniprot
proteins
sequence_length
1283
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Recycling endosome {ECO:0000269|PubMed:11786538, ECO:0000269|PubMed:15181150, ECO:0000269|PubMed:15280022, ECO:0000269|PubMed:15355514, ECO:0000269|PubMed:16920206}. Cytoplasmic vesicle {ECO:0000269|PubMed:26032412}. Note=RAB11A rather than RAB4A mediates localization in the endocytic recycling compartment (ERC). Colocalizes with Rab11 and RAB14 on punctate vesicles (PubMed:26032412). {ECO:0000269|PubMed:26032412}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasmic vesicle, phagosome membrane. Note=Membrane-bound (isoform 2). Colocalizes with RAB11A at phagosomes (isoform 2).
uniprot
proteins