SPINT1
entrez
6692
canonical
uniprot
O43278
canonical
ensembl
ENSG00000166145
resolver
ensp
ENSP00000342098
resolver
ensp
ENSP00000457076
resolver
ensp
ENSP00000577933
resolver
ensp
ENSP00000577934
resolver
ensp
ENSP00000591001
resolver
ensp
ENSP00000591002
resolver
ensp
ENSP00000613784
resolver
genesymbol
SPINT1
resolver
genesymbol_syn
HAI1
resolver
hgnc
HGNC:11246
resolver
uniprot
Q7Z7D2
resolver
uniprot_entry
SPIT1_HUMAN
resolver
uniprot_sec
Q7Z7D2
resolver
amino_acid_sequence
MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPGFVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLINCLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLVLKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
uniprot
proteins
function
FUNCTION: Inhibitor of HGFAC (PubMed:9045658). Inhibits serine protease activity of ST14/matriptase in vitro (PubMed:28710277). Inhibits serine protease activity of TMPRSS13, via the BPTI/Kunitz inhibitor 1 domain (PubMed:20977675). {ECO:0000269|PubMed:20977675, ECO:0000269|PubMed:28710277, ECO:0000269|PubMed:9045658}.
uniprot
proteins
mass_dalton
58398
uniprot
proteins
pubmed
10373425
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15713485
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20977675
uniprot
proteins
pubmed
28710277
uniprot
proteins
pubmed
9045658
uniprot
proteins
sequence_length
529
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:9045658}. Cytoplasm {ECO:0000269|PubMed:28710277}. Cell membrane {ECO:0000269|PubMed:28710277}.
uniprot
proteins