MSH5
entrez
4439
canonical
uniprot
O43196
canonical
ensembl
ENSG00000204410
resolver
ensembl
ENSG00000227314
resolver
ensembl
ENSG00000230293
resolver
ensembl
ENSG00000230961
resolver
ensembl
ENSG00000235222
resolver
ensembl
ENSG00000254405
resolver
ensembl
ENSG00000255152
resolver
ensembl
ENSG00000266027
resolver
ensembl
ENSG00000266442
resolver
ensp
ENSP00000364855
resolver
ensp
ENSP00000364892
resolver
ensp
ENSP00000364903
resolver
ensp
ENSP00000364908
resolver
ensp
ENSP00000396509
resolver
ensp
ENSP00000400187
resolver
ensp
ENSP00000404892
resolver
enst
ENST00000412070
resolver
enst
ENST00000420731
resolver
enst
ENST00000436091
resolver
genesymbol
MSH5
resolver
hgnc
HGNC:7328
resolver
uniprot
B0V033
resolver
uniprot
B0V034
resolver
uniprot
O60586
resolver
uniprot
Q5BLU9
resolver
uniprot
Q5SSR1
resolver
uniprot
Q8IW44
resolver
uniprot
Q9BQC7
resolver
uniprot_entry
MSH5_HUMAN
resolver
uniprot_sec
B0V033
resolver
uniprot_sec
B0V034
resolver
uniprot_sec
O60586
resolver
uniprot_sec
Q5BLU9
resolver
uniprot_sec
Q5SSR1
resolver
uniprot_sec
Q8IW44
resolver
uniprot_sec
Q9BQC7
resolver
amino_acid_sequence
MASLGANPRRTPQGPRPGAASSGFPSPAPVPGPREAEEEEVEEEEELAEIHLCVLWNSGYLGIAYYDTSDSTIHFMPDAPDHESLKLLQRVLDEINPQSVVTSAKQDENMTRFLGKLASQEHREPKRPEIIFLPSVDFGLEISKQRLLSGNYSFIPDAMTATEKILFLSSIIPFDCLLTVRALGGLLKFLGRRRIGVELEDYNVSVPILGFKKFMLTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQEFSDDLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLLKKNQMENCQTLVDKFMKLDLEDPNLDLNVFMSQEVLPAATSIL
uniprot
proteins
disease_involvement
DISEASE: Premature ovarian failure 13 (POF13) [MIM:617442]: An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. {ECO:0000269|PubMed:28175301}. Note=The disease is caused by variants affecting the gene represented in this entry.; DISEASE: Spermatogenic failure 74 (SPGF74) [MIM:619937]: An autosomal recessive male infertility disorder characterized by non-obstructive azoospermia due to complete meiotic arrest at the spermatocyte zygotene or pachytene stage. Some men exhibit reduced testicular volume and/or reduced testosterone level. {ECO:0000269|PubMed:34755185}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
92875
uniprot
proteins
protein_family
DNA mismatch repair MutS family
uniprot
proteins
pubmed
10029069
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14656967
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17823411
uniprot
proteins
pubmed
28175301
uniprot
proteins
pubmed
34755185
uniprot
proteins
pubmed
9740671
uniprot
proteins
pubmed
9787078
uniprot
proteins
sequence_length
834
uniprot
proteins