Agtr2
entrez
11609
canonical
uniprot
P35374
canonical
ensembl
ENSMUSG00000068122
resolver
ensp
ENSMUSP00000086592
resolver
enst
ENSMUST00000089188
resolver
genesymbol
Agtr2
resolver
uniprot
Q3US12
resolver
uniprot_entry
AGTR2_MOUSE
resolver
uniprot_entry
Q3US12_MOUSE
resolver
amino_acid_sequence
MKDNFSFAATSRNITSSRPFDNLNATGTNESAFNCSHKPSDKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLALADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKGSSLREMDTFVS
uniprot
proteins
function
FUNCTION: Receptor for angiotensin II, a vasoconstricting peptide (PubMed:8726696). Primarily signals via a non-canonical G protein- and beta-arrestin independent pathways (By similarity). Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (PubMed:15539617). {ECO:0000250|UniProtKB:P50052, ECO:0000269|PubMed:15539617, ECO:0000269|PubMed:8726696}.
uniprot
proteins
mass_dalton
41374
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11444984
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15539617
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
7650042
uniprot
proteins
pubmed
8267573
uniprot
proteins
pubmed
8292631
uniprot
proteins
pubmed
8726696
uniprot
proteins
sequence_length
363
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15539617}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P50052}.
uniprot
proteins
transmembrane_region
TRANSMEM 46..70; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:P50052"; TRANSMEM 81..104; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:P50052"; TRANSMEM 115..140; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:P50052"; TRANSMEM 160..181; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:P50052"; TRANSMEM 207..232; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:P50052"; TRANSMEM 258..281; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:P50052"; TRANSMEM 295..320; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:P50052
uniprot
proteins