MAT2A
entrez
4144
canonical
uniprot
P31153
canonical
ensembl
ENSG00000168906
resolver
ensp
ENSP00000303147
resolver
genesymbol
MAT2A
resolver
genesymbol_syn
AMS2
resolver
genesymbol_syn
MATA2
resolver
hgnc
HGNC:6904
resolver
uniprot
A0A140VJP5
resolver
uniprot
A8K511
resolver
uniprot
B4DN45
resolver
uniprot
D6W5L1
resolver
uniprot
Q53SP5
resolver
uniprot_entry
A0A140VJP5_HUMAN
resolver
uniprot_entry
METK2_HUMAN
resolver
uniprot_sec
A8K511
resolver
uniprot_sec
B4DN45
resolver
uniprot_sec
D6W5L1
resolver
uniprot_sec
Q53SP5
resolver
amino_acid_sequence
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
uniprot
proteins
ec_number
2.5.1.6
uniprot
proteins
function
FUNCTION: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. {ECO:0000269|PubMed:10644686, ECO:0000269|PubMed:23189196, ECO:0000269|PubMed:25075345}.
uniprot
proteins
mass_dalton
43661
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1. {ECO:0000269|PubMed:10644686, ECO:0000269|PubMed:23189196, ECO:0000269|PubMed:25075345}.
uniprot
proteins
protein_family
AdoMet synthase family
uniprot
proteins
pubmed
10644686
uniprot
proteins
pubmed
1426236
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16413417
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23189196
uniprot
proteins
pubmed
23425511
uniprot
proteins
pubmed
25075345
uniprot
proteins
pubmed
26858410
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
28525753
uniprot
proteins
pubmed
29262316
uniprot
proteins
pubmed
33930289
uniprot
proteins
sequence_length
395
uniprot
proteins