Dennd6a
entrez
211922
canonical
uniprot
Q8BH65
canonical
ensembl
ENSMUSG00000040818
resolver
ensp
ENSMUSP00000039361
resolver
ensp
ENSMUSP00000144906
resolver
ensp
ENSMUSP00000152966
resolver
ensp
ENSMUSP00000153187
resolver
genesymbol
Dennd6a
resolver
uniprot
Q3UX21
resolver
uniprot
Q6KAP4
resolver
uniprot
Q8BSG0
resolver
uniprot
Q8C4Z7
resolver
uniprot
Q8K2E8
resolver
uniprot
Q8R136
resolver
uniprot_entry
DEN6A_MOUSE
resolver
uniprot_sec
Q3UX21
resolver
uniprot_sec
Q6KAP4
resolver
uniprot_sec
Q8BSG0
resolver
uniprot_sec
Q8C4Z7
resolver
uniprot_sec
Q8K2E8
resolver
uniprot_sec
Q8R136
resolver
amino_acid_sequence
MALPGPAVFGPGSRGSLDEAGAEGREAAALAAAGVALEDEEEDDGRRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDEFDKDLPVYLKKDPAYFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGKTLHLPIMGLVMKVRIPTCHDKPGTTQMVQLTQQADTHTSIILPTVHEVDLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYTTRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSKPGVYTSYKPYLNRDEEIIKQLQKGIQQKRPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSGIKGDWIGLYRQFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQAGRESLPVKPDTVEKLRTHIDAIILALPDDLQGILLKTGMT
uniprot
proteins
function
FUNCTION: Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
68967
uniprot
proteins
protein_family
DENND6 family
uniprot
proteins
pubmed
15449545
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21330364
uniprot
proteins
sequence_length
605
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Recycling endosome {ECO:0000250}. Cytoplasm {ECO:0000250}.
uniprot
proteins