BOC
entrez
91653
canonical
uniprot
Q9BWV1
canonical
ensembl
ENSG00000144857
resolver
ensp
ENSP00000273395
resolver
ensp
ENSP00000417337
resolver
ensp
ENSP00000418663
resolver
ensp
ENSP00000420154
resolver
ensp
ENSP00000507783
resolver
ensp
ENSP00000579694
resolver
ensp
ENSP00000579695
resolver
ensp
ENSP00000579699
resolver
ensp
ENSP00000579706
resolver
ensp
ENSP00000579708
resolver
ensp
ENSP00000579709
resolver
ensp
ENSP00000579711
resolver
ensp
ENSP00000579714
resolver
ensp
ENSP00000598257
resolver
ensp
ENSP00000629951
resolver
ensp
ENSP00000725899
resolver
ensp
ENSP00000753692
resolver
ensp
ENSP00000785781
resolver
ensp
ENSP00000785783
resolver
ensp
ENSP00000795659
resolver
enst
ENST00000484034
resolver
enst
ENST00000485230
resolver
genesymbol
BOC
resolver
hgnc
HGNC:17173
resolver
uniprot
A6NJ30
resolver
uniprot
B2RMS8
resolver
uniprot
D3DN70
resolver
uniprot
F6UR31
resolver
uniprot
Q6UXJ5
resolver
uniprot
Q8N2P7
resolver
uniprot
Q8NF26
resolver
uniprot
Q96DN7
resolver
uniprot_entry
BOC_HUMAN
resolver
uniprot_entry
F6UR31_HUMAN
resolver
uniprot_entry
Q96DN7_HUMAN
resolver
uniprot_sec
A6NJ30
resolver
uniprot_sec
B2RMS8
resolver
uniprot_sec
D3DN70
resolver
uniprot_sec
Q6UXJ5
resolver
uniprot_sec
Q8N2P7
resolver
uniprot_sec
Q8NF26
resolver
amino_acid_sequence
MLRGTMTAWRGMRPEVTLACLLLATAGCFADLNEVPQVTVQPASTVQKPGGTVILGCVVEPPRMNVTWRLNGKELNGSDDALGVLITHGTLVITALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRTSRPSITPRLWQDAELATGTPPVSPSKLGNPEQMLRGQPALPRPPTSVGPASPQCPGEKGQGAPAEAPIILSSPRTSKTDSYELVWRPRHEGSGRAPILYYVVKHRKVTNSSDDWTISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIMASKEQQIQRDDPGASPQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDKYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQPGRLPPPTLAPPQPPLPETIERPVGTGAMVARSSDLPYLIVGVVLGSIVLIIVTFIPFCLWRAWSKQKHTTDLGFPRSALPPSCPYTMVPLGGLPGHQASGQPYLSGISGRACANGIHMNRGCPSAAVGYPGMKPQQHCPGELQQQSDTSSLLRQTHLGNGYDPQSHQITRGPKSSPDEGSFLYTLPDDSTHQLLQPHHDCCQRQEQPAAVGQSGVRRAPDSPVLEAVWDPPFHSGPPCCLGLVPVEEVDSPDSCQVSGGDWCPQHPVGAYVGQEPGMQLSPGPLVRVSFETPPLTI
uniprot
proteins
function
FUNCTION: Together with CDON, forms a coreceptor required for sonic hedgehog (SHH) handoff to its patched receptor (PTCH1 or PTCH2), thereby allowing activation of the smoothened signaling pathway (By similarity). Binds to the dually lipid-modified Sonic hedgehog protein N-product (ShhN) downstream of SCUBE2 carrier and promotes its release to GAS1 (By similarity). ShhN is then directly transferred to patched receptor by GAS1 (By similarity). May also mediate cell-cell interactions between muscle precursor cells, promoting differentiation of myogenic cells (By similarity). {ECO:0000250|UniProtKB:Q6AZB0}.
uniprot
proteins
mass_dalton
121059
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:11782431}.
uniprot
proteins
pubmed
11782431
uniprot
proteins
pubmed
12634428
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
20519495
uniprot
proteins
sequence_length
1114
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12634428}; Single-pass type I membrane protein {ECO:0000255}. Note=Enriched at sites of cell-cell contact. {ECO:0000269|PubMed:12634428}.
uniprot
proteins
transmembrane_region
TRANSMEM 856..876; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins