Rhot2
entrez
287156
canonical
uniprot
Q7TSA0
canonical
ensembl
ENSRNOG00000019930
resolver
ensp
ENSRNOP00000027083
resolver
enst
ENSRNOT00000027083
resolver
genesymbol
Rhot2
resolver
genesymbol_syn
Arht2
resolver
uniprot_entry
MIRO2_RAT
resolver
amino_acid_sequence
MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPADVTPEKVPTHIVDYSEAEQTEEELQEEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTIEAVLPIMSQFPEIETCVECSAKHLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRLSDQDLDHALSDKELNAFQKSCFGHPLAPQALEDVKRVVCKNVAGGVQDDRLTLEGFLFLNTLFIQRGRHETTWTILRRFGYSDSLELTPDYLCPPLYVPPGCSTELNHRGYQFVQRVFEKHDQDHDGVLSPTELESLFSVFSVAPWGPELLHTVPTEAGCLSLRGYLCQWTLVTYLDVQHCLAHLGYLGYPTLCEQDSQAQAITVTREKRLDQEKGQTQRSVLMCKVLGARGVGKSAFLQAFLGHSLGEARDRDAPEKLPTHTINTVRVSGQEKYLILCEVNADSLLDTSLDTTCDVACLMFDSSDPETFVQCATIYKRYYMDGQTPCLFISSKADLPEGVAPPGLSPAEFCRRHRLPAPASFSCLGPAQSSIDVFTQLATMATFPHLAHTELHPTPFWLRGVLVAVGTAVAAVLSFSLYRVLVKSR
uniprot
proteins
ec_number
3.6.5.-
uniprot
proteins
function
FUNCTION: Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Can hydrolyze GTP, ATP and UTP (By similarity). {ECO:0000250|UniProtKB:Q8IXI1, ECO:0000250|UniProtKB:Q8IXI2}.
uniprot
proteins
mass_dalton
69153
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by PRKN in a PINK1-dependent manner, leading to its degradation. {ECO:0000250|UniProtKB:Q8IXI1}.
uniprot
proteins
protein_family
Mitochondrial Rho GTPase family
uniprot
proteins
pubmed
15218247
uniprot
proteins
pubmed
24995978
uniprot
proteins
sequence_length
622
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8IXI1}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q8IXI1}. Note=Colocalizes with MGARP and RHOT2 at the mitochondria. {ECO:0000250|UniProtKB:Q8IXI1}.
uniprot
proteins
transmembrane_region
TRANSMEM 597..619; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins