POLR1D
entrez
51082
canonical
uniprot
P0DPB5
canonical
uniprot
P0DPB6
canonical
ensembl
ENSG00000186184
resolver
ensp
ENSP00000302478
resolver
ensp
ENSP00000382604
resolver
ensp
ENSP00000478213
resolver
ensp
ENSP00000489713
resolver
ensp
ENSP00000490619
resolver
ensp
ENSP00000508846
resolver
ensp
ENSP00000539932
resolver
ensp
ENSP00000597263
resolver
ensp
ENSP00000664336
resolver
enst
ENST00000302979
resolver
enst
ENST00000399697
resolver
enst
ENST00000621089
resolver
enst
ENST00000637071
resolver
enst
ENST00000637180
resolver
enst
ENST00000693488
resolver
enst
ENST00000869873
resolver
enst
ENST00000927204
resolver
genesymbol
POLR1D
resolver
hgnc
HGNC:20422
resolver
uniprot
A0A087WTY1
resolver
uniprot
Q5TBX2
resolver
uniprot
Q96BR3
resolver
uniprot
Q9Y2S0
resolver
uniprot_entry
A0A087WTY1_HUMAN
resolver
uniprot_entry
RPAC2_HUMAN
resolver
uniprot_entry
RPC22_HUMAN
resolver
uniprot_sec
Q5TBX2
resolver
uniprot_sec
Q96BR3
resolver
uniprot_sec
Q9Y2S0
resolver
amino_acid_sequence
MEEDQELERKAIEELLKEAKRGKTRAETMGPMGWMKCPLASTNKRFLINTIKNTLPSHKEQDHEQKEGDKEPAKSQAQKEENPKKHRSHPYKHSFRARGSASYSPPRKRSSQDKYEKRSNRR
uniprot
proteins
amino_acid_sequence
MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIMKNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKDYKDQKASRNESTF
uniprot
proteins
disease_involvement
DISEASE: Treacher Collins syndrome 2 (TCS2) [MIM:613717]: A form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss. {ECO:0000269|PubMed:21131976}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. {ECO:0000250|UniProtKB:P28000, ECO:0000269|PubMed:20413673, ECO:0000269|PubMed:34671025, ECO:0000269|PubMed:34887565, ECO:0000269|PubMed:35637192, ECO:0000269|PubMed:36271492}.
uniprot
proteins
mass_dalton
14332
uniprot
proteins
mass_dalton
15237
uniprot
proteins
protein_family
Archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family
uniprot
proteins
pubmed
12391170
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20413673
uniprot
proteins
pubmed
21131976
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
33335104
uniprot
proteins
pubmed
33558764
uniprot
proteins
pubmed
33558766
uniprot
proteins
pubmed
33674783
uniprot
proteins
pubmed
34671025
uniprot
proteins
pubmed
34675218
uniprot
proteins
pubmed
34887565
uniprot
proteins
pubmed
35637192
uniprot
proteins
pubmed
36271492
uniprot
proteins
sequence_length
122
uniprot
proteins
sequence_length
133
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:33335104}. Nucleus, nucleolus {ECO:0000305|PubMed:34887565}.
uniprot
proteins