Ghrl
entrez
58991
canonical
uniprot
Q9EQX0
canonical
ensembl
ENSMUSG00000064177
resolver
ensp
ENSMUSP00000069567
resolver
ensp
ENSMUSP00000145096
resolver
ensp
ENSMUSP00000145281
resolver
ensp
ENSMUSP00000145366
resolver
ensp
ENSMUSP00000145514
resolver
enst
ENSMUST00000203363
resolver
enst
ENSMUST00000203588
resolver
genesymbol
Ghrl
resolver
genesymbol_syn
Ghrelin
resolver
genesymbol_syn
Mtlrp
resolver
uniprot
A0A0N4SW44
resolver
uniprot
A0A0N4SWG9
resolver
uniprot
A2RSS9
resolver
uniprot
Q7TSD1
resolver
uniprot
Q811T4
resolver
uniprot
Q9WUZ1
resolver
uniprot_entry
A0A0N4SW44_MOUSE
resolver
uniprot_entry
A0A0N4SWG9_MOUSE
resolver
uniprot_entry
A2RSS9_MOUSE
resolver
uniprot_entry
GHRL_MOUSE
resolver
uniprot_entry
Q7TSD1_MOUSE
resolver
uniprot_entry
Q811T4_MOUSE
resolver
uniprot_sec
Q9WUZ1
resolver
amino_acid_sequence
MLSSGTICSLLLLSMLWMDMAMAGSSFLSPEHQKAQQRKESKKPPAKLQPRALEGWLHPEDRGQAEETEEELEIRFNAPFDVGIKLSGAQYQQHGRALGKFLQDILWEEVKEAPADK
uniprot
proteins
function
FUNCTION: Precursor of the appetite-regulating peptide ghrelin, including ghrelin-27 and ghrelin-28. {ECO:0000250|UniProtKB:Q9UBU3}.; FUNCTION: [Ghrelin-27]: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. {ECO:0000250|UniProtKB:Q9UBU3}.; FUNCTION: [Ghrelin-28]: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Octanoylated ghrelin-28 is the most commonly found ghrelin and octanoylation is essential for the activation of the growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. {ECO:0000250|UniProtKB:Q9UBU3}.; FUNCTION: [Obestatin]: May have an appetite-reducing effect resulting in decreased food intake (By similarity). May reduce gastric emptying activity and jejunal motility (By similarity). {ECO:0000250|UniProtKB:Q9QYH7}.
uniprot
proteins
mass_dalton
13207
uniprot
proteins
post_translational_modification
PTM: O-octanoylated by GOAT/MBOAT4 (PubMed:18443287). O-octanoylation or O-decanoylation is essential for ghrelin activity (By similarity). The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26 (PubMed:15746259). A small fraction of ghrelin, ghrelin-28-C10:1, may be modified with a singly unsaturated carboxylic acid (By similarity). Also O-acetylated and O-butyrylated on Ser-26 to minor levels (PubMed:18443287). {ECO:0000250|UniProtKB:Q9UBU3, ECO:0000269|PubMed:15746259, ECO:0000269|PubMed:18443287}.; PTM: Amidation of Leu-98 is essential for obestatin activity. {ECO:0000269|PubMed:17904104}.
uniprot
proteins
protein_family
Motilin family
uniprot
proteins
pubmed
10930375
uniprot
proteins
pubmed
11306336
uniprot
proteins
pubmed
14585959
uniprot
proteins
pubmed
15677766
uniprot
proteins
pubmed
15746259
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16679295
uniprot
proteins
pubmed
17904104
uniprot
proteins
pubmed
18443287
uniprot
proteins
sequence_length
117
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:10930375}.
uniprot
proteins