Oc90
entrez
18256
canonical
uniprot
Q9Z0L3
canonical
ensembl
ENSMUSG00000015001
resolver
ensp
ENSMUSP00000062865
resolver
ensp
ENSMUSP00000078709
resolver
ensp
ENSMUSP00000114254
resolver
ensp
ENSMUSP00000121227
resolver
enst
ENSMUST00000079776
resolver
genesymbol
Oc90
resolver
genesymbol_syn
Onc-95
resolver
genesymbol_syn
Pla2ll
resolver
uniprot
F6TLK6
resolver
uniprot
Q80ZM2
resolver
uniprot
Q9CZ60
resolver
uniprot
Q9Z225
resolver
uniprot_entry
F6TLK6_MOUSE
resolver
uniprot_entry
OC90_MOUSE
resolver
uniprot_entry
Q80ZM2_MOUSE
resolver
uniprot_sec
Q9CZ60
resolver
uniprot_sec
Q9Z225
resolver
amino_acid_sequence
MIMLLMVGMLMAPCVGAHALDTPNPQELPPGLSKNINITFFNGVFKNVESVAEIFDCLGSHFTWLQAVFTNFPLLLQFVNSMRCVTGLCPRDFEDYGCACRFEMEGMPVDESDICCFQHRRCYEEAVEMDCLQDPAKLSADVDCTNKQITCESEDPCERLLCTCDKAAVECLAQSGINSSLNFLDASFCLPQTPETTSGKAATLLPRGIPEKPTDTSQIALSGEVAGEVRADTLTTLSRTKSVQDLQDTQASRTTSSPGSAEIIALAKGTTHSAGIKPLRLGVSSVDNGSQEAAGKACDRLAFVHLGDGDSMTAMLQLGEMLFCLTSHCPEEFETYGCYCGREGRGEPRDTLDRCCLSHHCCLEQMRQVGCLHGRRSQSSVVCEDHMAKCVGQSLCEKLLCACDQMAAECMASAFFNQSLKSPDGAECQGEPVSCEDGMLQGTLASSVDSSSEENSEEAPPQMERLRRFLEKPPGPLGARPLGGK
uniprot
proteins
function
FUNCTION: Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear (PubMed:17300776). Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure (PubMed:21655225, PubMed:24748133). Together with OTOL1, modulates calcite crystal morphology and growth kinetics (PubMed:24748133). It is unlikely that this protein has phospholipase A2 activity (PubMed:17300776). {ECO:0000269|PubMed:17300776, ECO:0000269|PubMed:21655225, ECO:0000269|PubMed:24748133}.
uniprot
proteins
mass_dalton
52445
uniprot
proteins
protein_family
Phospholipase A2 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17300776
uniprot
proteins
pubmed
20856818
uniprot
proteins
pubmed
21655225
uniprot
proteins
pubmed
24748133
uniprot
proteins
pubmed
9860971
uniprot
proteins
pubmed
9892667
uniprot
proteins
sequence_length
485
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P81869}.
uniprot
proteins