Cavin3
entrez
85332
canonical
uniprot
Q9Z1H9
canonical
ensembl
ENSRNOG00000017914
resolver
ensembl
ENSRNOG00055024102
resolver
ensembl
ENSRNOG00060017724
resolver
ensp
ENSRNOP00000024119
resolver
ensp
ENSRNOP00055033678
resolver
ensp
ENSRNOP00060024503
resolver
enst
ENSRNOT00000024119
resolver
enst
ENSRNOT00055041386
resolver
enst
ENSRNOT00060030344
resolver
genesymbol
Cavin3
resolver
genesymbol_syn
Dig2
resolver
genesymbol_syn
Prkcdbp
resolver
genesymbol_syn
Srbc
resolver
uniprot
P97585
resolver
uniprot_entry
CAVN3_RAT
resolver
uniprot_sec
P97585
resolver
amino_acid_sequence
MGESALEPGPVPGAPAGGPVHAVTVVTLLEKLATMLEALRERQGGLAERQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVGSHADAAQERAVHRAAQVQRLEANHGLLVARGKLHVLLFKEETEIPARAFQKAPELLGPEDQLVLGPEQPEDEVGESSDEEPVESRAQRLRRTGLQKVQSLKRAFSSRKGSEAAQPTPVKPPRLGPVRNSEGPAEGQPAAQPAMEPVLPSALEPEPPQPTKEDPERPVLQIESAA
uniprot
proteins
function
FUNCTION: Regulates the traffic and/or budding of caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity). Seems to have an immune potentiation function, especially in the glioma (PubMed:15197346). {ECO:0000250|UniProtKB:Q91VJ2, ECO:0000250|UniProtKB:Q969G5, ECO:0000269|PubMed:15197346}.
uniprot
proteins
mass_dalton
27910
uniprot
proteins
post_translational_modification
PTM: In vitro, phosphorylated by PRKCD. {ECO:0000250|UniProtKB:Q91VJ2}.
uniprot
proteins
protein_family
CAVIN family
uniprot
proteins
pubmed
15197346
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8968041
uniprot
proteins
pubmed
9054438
uniprot
proteins
sequence_length
263
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q91VJ2}. Membrane, caveola {ECO:0000250|UniProtKB:Q91VJ2}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q91VJ2}. Note=Localizes in the caveolae in a caveolin-dependent manner. {ECO:0000250|UniProtKB:Q91VJ2}.
uniprot
proteins