Tmem260
entrez
218989
canonical
uniprot
Q8BMD6
canonical
ensembl
ENSMUSG00000036339
resolver
ensp
ENSMUSP00000107364
resolver
ensp
ENSMUSP00000118376
resolver
ensp
ENSMUSP00000335137
resolver
genesymbol
Tmem260
resolver
uniprot
Q6GT69
resolver
uniprot
Q80SZ4
resolver
uniprot
Q8BMG3
resolver
uniprot
Q8BW28
resolver
uniprot
Q8BYU4
resolver
uniprot_entry
TM260_MOUSE
resolver
uniprot_sec
Q6GT69
resolver
uniprot_sec
Q80SZ4
resolver
uniprot_sec
Q8BMG3
resolver
uniprot_sec
Q8BW28
resolver
uniprot_sec
Q8BYU4
resolver
amino_acid_sequence
MGLHGDGGSPAAGAGPWRSGALRGSVAVFASVAAVFTLTLPRSLPGGDSGELITAAHELGVAHPPGYPLFTLLASLTITLFPFGSVAYRVNLLCGLFGAVAASLLFYTVFRLSGSHAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVRFEEATAAKERSKIAAIGAFSCGLSLCNQHTIVLYILCIIPWILFRLLKEKELTLSLLLRLTLAFSAGLLPYVYLPVSSYLSRARWTWGDQTTLRGFLTHFFREEYGTFSLAKSEVGSSVSTVLLSQVINMKTELSFNIQALAVWANICLARKDRRKSSVVWLFTGMLCLYSLFFAWRANLDISKPLFMGVVERFWLQSNAVVAVLAGLGLATLVSETNRVLHCTGIRNLEWLSAALFVAYQVYSNYSICDQRTNNVIDQFARNLLDSMPQDAIILLRGDLPGNALRYLHYCEGLRPDVSLVDQEMMTYEWYLPKMARHLPGVHFPGDRWNPVEGVLPSGMVTFNLYHFLEMNKQKETFVCIGIHEGDPTWKKDYSLWPWGSCDKLVPSKIVFNPEEWIERTRAIYNWTEAYERFGPSSWESVANEEMWQARMKTPFFIFSLAESAAVPADVKAQLYTHAYKLYKEIVYLQEEHPVNWHKNYAIACERMLRLPGTGIDPEVLLSEAIRHFHLYTQKAQNDPQRADIIAALKHLRRELQSLRNIKKV
uniprot
proteins
ec_number
2.4.1.109
uniprot
proteins
function
FUNCTION: O-mannosyl-transferase that transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins. Specifically glycosylates the IPT/TIG domain of target proteins, such as MET and MST1R/RON. TMEM260-mediated O-mannosylated residues are composed of single mannose glycans that are not elongated or modified. {ECO:0000250|UniProtKB:Q9NX78}.
uniprot
proteins
mass_dalton
78947
uniprot
proteins
protein_family
Glycosyltransferase 117 (GT117) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
37186866
uniprot
proteins
sequence_length
703
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9NX78}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..40; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 90..110; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 137..157; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 182..202; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 218..238; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 352..372; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins