Sco2
entrez
100126824
canonical
uniprot
Q8VCL2
canonical
ensembl
ENSMUSG00000091780
resolver
ensp
ENSMUSP00000131943
resolver
ensp
ENSMUSP00000155150
resolver
enst
ENSMUST00000167643
resolver
enst
ENSMUST00000228977
resolver
genesymbol
Sco2
resolver
uniprot_entry
SCO2_MOUSE
resolver
amino_acid_sequence
MLLALGPKAWPKLSQFKPLLRISGGETLHRNSRHWAGQGQRQGPGLRTRLLITALFGAGLGWAWLAARAEKEQWRQQQRTEALRQAAVGQGDFSLLDHKGQPRCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRKLEAEPDLPLVQPVFITVDPERDDVAAMARYVQEFHPRLLGLTGSTEQVAHASRNYRVYYSAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAEQIVESIRRHIAAFHSVLP
uniprot
proteins
function
FUNCTION: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2); together with SCO1, facilitates the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2. {ECO:0000250|UniProtKB:O43819}.
uniprot
proteins
mass_dalton
28944
uniprot
proteins
protein_family
SCO1/2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23643385
uniprot
proteins
sequence_length
255
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:O43819}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 50..67; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins