Dennd5a
entrez
19347
canonical
uniprot
Q6PAL8
canonical
ensembl
ENSMUSG00000035901
resolver
ensp
ENSMUSP00000079295
resolver
ensp
ENSMUSP00000102333
resolver
enst
ENSMUST00000080437
resolver
enst
ENSMUST00000106722
resolver
genesymbol
Dennd5a
resolver
genesymbol_syn
Rab6ip1
resolver
uniprot
A0A0R4J1B6
resolver
uniprot
Q62146
resolver
uniprot
Q8C829
resolver
uniprot
Q8VDF6
resolver
uniprot
Q9QYZ2
resolver
uniprot_entry
A0A0R4J1B6_MOUSE
resolver
uniprot_entry
DEN5A_MOUSE
resolver
uniprot_sec
Q62146
resolver
uniprot_sec
Q8C829
resolver
uniprot_sec
Q8VDF6
resolver
uniprot_sec
Q9QYZ2
resolver
amino_acid_sequence
MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVDWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPLADGGDQSGMEDGEGIPGTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDVDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGVPPEGNLHCSESASKLKRIRASELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDFKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAVHPHLLDMKIGQGKYEPGFFPKLQSDVLCTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARNMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQENRQRKLTSGSLSTSGILLDSERRKSDASAVMSPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQILQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVECVMVRNEVTGHTYKFPCGRWLGKGMDDGSLERVLVGELLTSLPEVDERPCRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEQNDVVPEENWHTRARNFCRFVTAVNNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLDTSLVKGIDI
uniprot
proteins
function
FUNCTION: Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth (By similarity). {ECO:0000250|UniProtKB:G3V7Q0, ECO:0000250|UniProtKB:Q6IQ26}.
uniprot
proteins
mass_dalton
146653
uniprot
proteins
mutagenesis
MUTAGEN 763; /note="K->E: Abolishes the interaction with RAP6A and localization to Golgi membrane."; /evidence="ECO:0000269|PubMed:19141279"; MUTAGEN 932; /note="Y->S: Abolishes the interaction with RAP6A and localization to Golgi membrane; when associated with Ala-935."; /evidence="ECO:0000269|PubMed:19141279"; MUTAGEN 935; /note="L->A: Abolishes the interaction with RAP6A and localization to Golgi membrane; when associated with Ser-932."; /evidence="ECO:0000269|PubMed:19141279
uniprot
proteins
protein_family
RAB6IP1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19141279
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22558185
uniprot
proteins
pubmed
7782346
uniprot
proteins
sequence_length
1287
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:19141279, ECO:0000269|PubMed:22558185}.
uniprot
proteins