Commd3
entrez
291339
canonical
uniprot
Q6P9U3
canonical
ensembl
ENSRNOG00000016383
resolver
ensembl
ENSRNOG00055010756
resolver
ensembl
ENSRNOG00060019778
resolver
ensembl
ENSRNOG00065006762
resolver
ensp
ENSRNOP00000022201
resolver
ensp
ENSRNOP00055014605
resolver
ensp
ENSRNOP00060027989
resolver
ensp
ENSRNOP00065007736
resolver
enst
ENSRNOT00000022201
resolver
enst
ENSRNOT00055018182
resolver
enst
ENSRNOT00060034149
resolver
enst
ENSRNOT00065010513
resolver
genesymbol
Commd3
resolver
uniprot_entry
COMD3_RAT
resolver
amino_acid_sequence
MELSEYVQRGIQTLADPGSFDSSAFALLLRAAFQSLLDAQADEAALDHPDLKHIDPVVLKHCHGAAATYILEAGKHRVDKSTLSTYLEDCKFDRERIELFCTEYQNNKNSLEILLGSIGRALPHITDVSWRLEYQIKTNQLHKMCRPGYLVTLNVENADSQSYPEISFSCSMEQLQDLVGKLKDASKSLERATQL
uniprot
proteins
function
FUNCTION: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity). May down-regulate activation of NF-kappa-B (By similarity). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (By similarity). {ECO:0000250|UniProtKB:Q9UBI1}.
uniprot
proteins
mass_dalton
21932
uniprot
proteins
protein_family
COMM domain-containing protein 3 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23637203
uniprot
proteins
sequence_length
195
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23637203}. Nucleus {ECO:0000250|UniProtKB:Q9UBI1}.
uniprot
proteins