Hmgn3
entrez
94353
canonical
uniprot
Q9DCB1
canonical
ensembl
ENSMUSG00000066456
resolver
ensp
ENSMUSP00000124278
resolver
ensp
ENSMUSP00000125616
resolver
ensp
ENSMUSP00000140980
resolver
genesymbol
Hmgn3
resolver
uniprot
Q7M737
resolver
uniprot
Q99JU1
resolver
uniprot_entry
HMGN3_MOUSE
resolver
uniprot_sec
Q7M737
resolver
uniprot_sec
Q99JU1
resolver
amino_acid_sequence
MPKRKSPENTEGKDGTKLTKQEPTRRSARLSAKPVPPKPESKPRKTSAKKEPGTKISRGAKGKKEEKQEAGEEGTAPSANGDTKVEEAQRTESIEKEGE
uniprot
proteins
function
FUNCTION: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function. {ECO:0000269|PubMed:12185205, ECO:0000269|PubMed:15082770, ECO:0000269|PubMed:18502697, ECO:0000269|PubMed:19651901, ECO:0000269|PubMed:19885867}.
uniprot
proteins
mass_dalton
10769
uniprot
proteins
protein_family
HMGN family
uniprot
proteins
pubmed
11356838
uniprot
proteins
pubmed
12185205
uniprot
proteins
pubmed
15082770
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18502697
uniprot
proteins
pubmed
19651901
uniprot
proteins
pubmed
19885867
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
99
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins