SIM2
entrez
6493
canonical
uniprot
Q14190
canonical
ensembl
ENSG00000159263
resolver
ensp
ENSP00000290399
resolver
genesymbol
SIM2
resolver
genesymbol_syn
BHLHE15
resolver
hgnc
HGNC:10883
resolver
uniprot
O60766
resolver
uniprot
Q15470
resolver
uniprot
Q15471
resolver
uniprot
Q15472
resolver
uniprot
Q15473
resolver
uniprot
Q16532
resolver
uniprot
Q2TBD8
resolver
uniprot_entry
SIM2_HUMAN
resolver
uniprot_sec
O60766
resolver
uniprot_sec
Q15470
resolver
uniprot_sec
Q15471
resolver
uniprot_sec
Q15472
resolver
uniprot_sec
Q15473
resolver
uniprot_sec
Q16532
resolver
uniprot_sec
Q2TBD8
resolver
amino_acid_sequence
MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRAGPLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHHHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLYSNMFMFRASLDLKLIFLDSRVTEVTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKRGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEIEYKELQLSLEQVSTAKSQDSWRTALSTSQETRKLVKPKNTKMKTKLRTNPYPPQQYSSFQMDKLECGQLGNWRASPPASAAAPPELQPHSESSDLLYTPSYSLPFSYHYGHFPLDSHVFSSKKPMLPAKFGQPQGSPCEVARFFLSTLPASGECQWHYANPLVPSSSSPAKNPPEPPANTARHSLVPSYEAPAAAVRRFGEDTAPPSFPSCGHYREEPALGPAKAARQAARDGARLALARAAPECCAPPTPEAPGAPAQLPFVLLNYHRVLARRGPLGGAAPAASGLACAPGGPEAATGALRLRHPSPAATSPPGAPLPHYLGASVIITNGR
uniprot
proteins
function
FUNCTION: Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development.
uniprot
proteins
mass_dalton
73219
uniprot
proteins
mutagenesis
MUTAGEN 367; /note="R->A,G: Reduced nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 368; /note="K->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 369; /note="L->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 370; /note="V->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 371; /note="K->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 372; /note="P->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 373; /note="K->A,G: Reduced nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 375; /note="T->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 376; /note="K->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 377; /note="M->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 378; /note="K->G: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 379; /note="T->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 380; /note="K->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 381; /note="L->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 382; /note="R->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 383; /note="T->A: No effect on nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 385; /note="P->A: Reduced nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214"; MUTAGEN 386; /note="Y->A: Reduced nuclear translocation."; /evidence="ECO:0000269|PubMed:14697214
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
14697214
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
7568099
uniprot
proteins
pubmed
7647800
uniprot
proteins
pubmed
8661114
uniprot
proteins
pubmed
8905236
uniprot
proteins
pubmed
9199934
uniprot
proteins
pubmed
9503011
uniprot
proteins
sequence_length
667
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00632, ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:14697214}.
uniprot
proteins