Sdhc
entrez
66052
canonical
uniprot
Q9CZB0
canonical
ensembl
ENSMUSG00000058076
resolver
ensp
ENSMUSP00000106968
resolver
ensp
ENSMUSP00000237181
resolver
enst
ENSMUST00000111336
resolver
genesymbol
Sdhc
resolver
uniprot
Q544Q9
resolver
uniprot
Q99JP2
resolver
uniprot
Q9DCU7
resolver
uniprot_entry
C560_MOUSE
resolver
uniprot_sec
Q544Q9
resolver
uniprot_sec
Q99JP2
resolver
uniprot_sec
Q9DCU7
resolver
amino_acid_sequence
MAAFLLRHVSRHCLRAHLNAQLCIRNAAPLGTTAKEEMERFWKKNTSSNRPLSPHLTIYKWSLPMALSVCHRGSGIALSGGVSLFGLSALLLPGNFESYLMFVKSLCLGPTLIYSAKFVLVFPLMYHSLNGIRHLLWDLGKGLAIPQVWLSGVAVVVLAVLSSGGLAAL
uniprot
proteins
function
FUNCTION: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). {ECO:0000250|UniProtKB:P35720, ECO:0000250|UniProtKB:Q99643}.
uniprot
proteins
mass_dalton
18382
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle. {ECO:0000250|UniProtKB:Q99643}.
uniprot
proteins
protein_family
Cytochrome b560 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
169
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q99643}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q99643}.
uniprot
proteins
transmembrane_region
TRANSMEM 63..92; /note="Helical"; /evidence="ECO:0000250|UniProtKB:D0VWV4"; TRANSMEM 113..137; /note="Helical"; /evidence="ECO:0000250|UniProtKB:D0VWV4"; TRANSMEM 145..166; /note="Helical"; /evidence="ECO:0000250|UniProtKB:D0VWV4
uniprot
proteins