Fcgr3
entrez
116591
canonical
uniprot
P27645
canonical
ensembl
ENSRNOG00000049422
resolver
ensembl
ENSRNOG00060024893
resolver
ensp
ENSRNOP00000004204
resolver
enst
ENSRNOT00000004204
resolver
genesymbol
Fcgr2a
resolver
genesymbol
Fcgr3
resolver
uniprot
A0A8L2Q236
resolver
uniprot
Q04798
resolver
uniprot
Q63204
resolver
uniprot_entry
A0A8L2Q236_RAT
resolver
uniprot_entry
FCGR3_RAT
resolver
uniprot_sec
Q04798
resolver
uniprot_sec
Q63204
resolver
amino_acid_sequence
MTLETQMFQNAHSGSQWLLPPLTMLLLFAFADRQTANLPKAVVKRDPPWIQVLKEDTVTLTCEGTHNPGNSSTQWFHNQSSTWGQVQASYTFKATVNDSGEYRCRMAHTSLSDPVHLEVISDWLLLQTPQLVFEEGETITLRCHSWKNKQLTKVLLFQNGKPVRYYYQSSNFSIPKANHSHSGNYYCKAYLGRTMHVSKPVTITVQGSATASTSSLVWFHAAFCLVMCLLFAVDTGLYFCVRRNLQTSGEDWRKSLSVGKYKAPQDK
uniprot
proteins
function
FUNCTION: Receptor for the Fc region of complexed immunoglobulins gamma (PubMed:1692135). Low affinity receptor which binds to IgG1, IgG2a and IgG2b (By similarity). Mediates neutrophil activation by IgG complexes redundantly with Fcgr4 (By similarity). {ECO:0000250|UniProtKB:P08508, ECO:0000269|PubMed:1692135}.
uniprot
proteins
mass_dalton
30282
uniprot
proteins
pubmed
1692135
uniprot
proteins
pubmed
1710249
uniprot
proteins
pubmed
8482840
uniprot
proteins
sequence_length
267
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P08508}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 222..241; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins