AGMAT
entrez
79814
canonical
uniprot
Q9BSE5
canonical
ensembl
ENSG00000116771
resolver
ensp
ENSP00000364986
resolver
enst
ENST00000375826
resolver
genesymbol
AGMAT
resolver
genesymbol_syn
GDAH
resolver
hgnc
HGNC:18407
resolver
uniprot
Q5TDH1
resolver
uniprot
Q9H5J3
resolver
uniprot_entry
GDAH_HUMAN
resolver
uniprot_sec
Q5TDH1
resolver
uniprot_sec
Q9H5J3
resolver
amino_acid_sequence
MLRLLASGCARGPGPGVGARPAAGLFHPGRRQSRQASDAPRNQPPSPEFVARPVGVCSMMRLPVQTSPEGLDAAFIGVPLDTGTSNRPGARFGPRRIREESVMLGTVNPSTGALPFQSLMVADLGDVNVNLYNLQDSCRRIQEAYEKIVAAGCIPLTLGGDHTITYPILQAMAKKHGPVGLLHVDAHTDTTDKALGEKLYHGAPFRRCVDEGLLDCKRVVQIGIRGSSTTLDPYRYNRSQGFRVVLAEDCWMKSLVPLMGEVRQQMGGKPIYISFDIDALDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVMGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV
uniprot
proteins
ec_number
3.5.3.-
uniprot
proteins
ec_number
3.5.3.1
uniprot
proteins
ec_number
3.5.3.17
uniprot
proteins
ec_number
3.5.3.7
uniprot
proteins
function
FUNCTION: Hydrolyzes linear guanidino acids to form urea and the corresponding amines. Displays specificity for substrates having a negatively charged head group and short chains including taurocyamine, guanidino propanoic and butanoic acids. May protect cells by detoxifying potentially harmful amounts of guanidino acids. Metabolizes L-arginine with low efficiency. {ECO:0000269|PubMed:36543883}.
uniprot
proteins
mass_dalton
37660
uniprot
proteins
pathway_participation
PATHWAY: Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. {ECO:0000305|PubMed:36543883}.
uniprot
proteins
protein_family
Arginase family
uniprot
proteins
protein_family
Ureohydrolase superfamily
uniprot
proteins
pubmed
11804860
uniprot
proteins
pubmed
11914032
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
36543883
uniprot
proteins
sequence_length
352
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255}.
uniprot
proteins