Amhr2
entrez
110542
canonical
uniprot
Q8K592
canonical
ensembl
ENSMUSG00000023047
resolver
ensp
ENSMUSP00000023809
resolver
enst
ENSMUST00000023809
resolver
genesymbol
Amhr2
resolver
uniprot
A0A2R8VHE2
resolver
uniprot
A0A2R8W6H9
resolver
uniprot
F6V9X7
resolver
uniprot
Q0VDQ4
resolver
uniprot
R4JKA2
resolver
uniprot
R4JNM3
resolver
uniprot_entry
AMHR2_MOUSE
resolver
uniprot_sec
A0A2R8VHE2
resolver
uniprot_sec
A0A2R8W6H9
resolver
uniprot_sec
F6V9X7
resolver
uniprot_sec
Q0VDQ4
resolver
uniprot_sec
R4JKA2
resolver
uniprot_sec
R4JNM3
resolver
amino_acid_sequence
MLGTLGLWTLLPAAAQVSPNRRTCVFFEAPGVRGSTKTLGEMVDAGPGPPKGIRCLYSHCCFGIWNLTHGRAQVEMQGCRDSDEPGCESLHCDPVPRAHPNPSSTLFTCSCGTDFCNANYSHLPPSGNQGAPGPQEPQATPGGPVWMALLLLGMFLVLLLSSIILALLQRKACRVQGGSDPEPGSGGDCSEELPELAELRFSQVIQEGGHAVVWAGRLQGEMVAIKAFPPRAVAQFRAERAVYQLLGLQHDHIVRFITAGQGGPGPLPSGPLLVLELYPKGSLCHYLTQYTSDWGSSLRMALSLAEGLAFLHEERWQDGQYKPGIAHRDLSSQNVLIREDRSCAIGDLGLALVLPGLAQPPALAPTQPRGPAAILEAGTQRYMAPELLDKTLDLQDWGTALQRADVYSLALLLWEILSRCSDLRPDHRPPPFQLAYEAELGSNPSACELWALAVEERKRPNIPSTWSCSATDPRGLRELLEDCWDADPEARLTAECVQQRLAALAYPHGASSFPESPQGCPENCLSAPASAVFPCRPQQSSCLLSVQQGPGSRSPDPVGDTVQVYVNE
uniprot
proteins
ec_number
2.7.11.30
uniprot
proteins
function
FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone (AMH) (PubMed:23624077). {ECO:0000269|PubMed:23624077}.; FUNCTION: [Isoform 2]: May act as a dominant negative inhibitor of AMH signaling. {ECO:0000269|PubMed:23624077}.; FUNCTION: [Isoform 3]: May act as a dominant negative inhibitor of AMH signaling. {ECO:0000269|PubMed:23624077}.
uniprot
proteins
mass_dalton
61195
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
TGFB receptor subfamily
uniprot
proteins
protein_family
TKL Ser/Thr protein kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23624077
uniprot
proteins
pubmed
9299437
uniprot
proteins
sequence_length
568
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 148..168; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins