TSPAN10
entrez
83882
canonical
uniprot
Q9H1Z9
canonical
ensembl
ENSG00000182612
resolver
ensp
ENSP00000482695
resolver
ensp
ENSP00000484664
resolver
ensp
ENSP00000512351
resolver
ensp
ENSP00000512352
resolver
ensp
ENSP00000539797
resolver
ensp
ENSP00000539798
resolver
ensp
ENSP00000539799
resolver
enst
ENST00000611590
resolver
enst
ENST00000621293
resolver
enst
ENST00000696047
resolver
enst
ENST00000696048
resolver
enst
ENST00000869738
resolver
enst
ENST00000869739
resolver
enst
ENST00000869740
resolver
genesymbol
TSPAN10
resolver
genesymbol_syn
OCSP
resolver
hgnc
HGNC:29942
resolver
uniprot
A0A087X235
resolver
uniprot
A0A8Q3WKY1
resolver
uniprot
F1T0E7
resolver
uniprot
F1T0E8
resolver
uniprot
Q6PJ65
resolver
uniprot
Q8N548
resolver
uniprot_entry
A0A8Q3WKY1_HUMAN
resolver
uniprot_entry
F1T0E7_HUMAN
resolver
uniprot_entry
F1T0E8_HUMAN
resolver
uniprot_entry
Q6PJ65_HUMAN
resolver
uniprot_entry
TSN10_HUMAN
resolver
uniprot_sec
A0A087X235
resolver
uniprot_sec
Q8N548
resolver
amino_acid_sequence
MEEGERSPLLSQETAGQKPLSVHRPPTSGCLGPVPREDQAEAWGCSCCPPETKHQALSGTPKKGPAPSLSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALAARRGAAYGPGARGEDRAGPQSPSPGAPPAAKPARG
uniprot
proteins
function
FUNCTION: Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. {ECO:0000269|PubMed:37516108}.
uniprot
proteins
mass_dalton
36644
uniprot
proteins
protein_family
Tetraspanin (TM4SF) family
uniprot
proteins
pubmed
12107410
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
37516108
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 121..141; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 155..175; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 291..311; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins