Nat8l
entrez
269642
canonical
uniprot
Q3UGX3
canonical
ensembl
ENSMUSG00000048142
resolver
ensp
ENSMUSP00000059313
resolver
enst
ENSMUST00000056355
resolver
genesymbol
Nat8l
resolver
uniprot
A0A0R4J0R4
resolver
uniprot
Q3UH43
resolver
uniprot
Q6DID6
resolver
uniprot
Q8K065
resolver
uniprot_entry
A0A0R4J0R4_MOUSE
resolver
uniprot_entry
NAT8L_MOUSE
resolver
uniprot_sec
Q3UH43
resolver
uniprot_sec
Q6DID6
resolver
uniprot_sec
Q8K065
resolver
activity_regulation
ACTIVITY REGULATION: Aminooxyacetic acid (AOAA) blocks its activity in both cytoplasm and mitochondria. {ECO:0000250|UniProtKB:Q8N9F0}.
uniprot
proteins
amino_acid_sequence
MHCGPPDMVCETKIVATEDHEALPGAKKDALLVAAGAMWPPLPAAPGPAAAPPPAAGPQPHGGTGGAGPPEGRGVCIREFRAAEQEAARRIFYDGILERIPNTAFRGLRQHPRTQLLYALLAALCFAVTRSLLLTCLVPAGLLALRYYYSRKVILAYLECALHTDMADIEQYYMKPPGSCFWVAVLDGNVVGIVAARAHEEDNTVELLRMSVDSRFRGKSIAKALGRRVLEFAMLHNYSAVVLGTTAVKVAAHKLYESLGFRHMGASDHYVLPGMTLSLAERLFFQVRYHRYRLQLREE
uniprot
proteins
ec_number
2.3.1.17
uniprot
proteins
function
FUNCTION: Catalyzes the synthesis of N-acetylaspartate acid (NAA) from L-aspartate and acetyl-CoA (PubMed:19807691, PubMed:20385109, PubMed:20643647). Promotes dopamine uptake by regulating TNF expression (PubMed:19014384). Attenuates methamphetamine-induced inhibition of dopamine uptake (By similarity). {ECO:0000250|UniProtKB:Q8N9F0, ECO:0000269|PubMed:19014384, ECO:0000269|PubMed:19807691, ECO:0000269|PubMed:20385109, ECO:0000269|PubMed:20643647}.
uniprot
proteins
mass_dalton
32777
uniprot
proteins
protein_family
NAT8 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17626222
uniprot
proteins
pubmed
19014384
uniprot
proteins
pubmed
19807691
uniprot
proteins
pubmed
20385109
uniprot
proteins
pubmed
20643647
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8N9F0}. Microsome membrane {ECO:0000250|UniProtKB:D3ZVU9}; Single-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q8N9F0}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:19807691}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 118..138; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins