Abhd10
entrez
213012
canonical
uniprot
Q6PE15
canonical
ensembl
ENSMUSG00000033157
resolver
ensp
ENSMUSP00000065282
resolver
ensp
ENSMUSP00000310049
resolver
genesymbol
Abhd10
resolver
uniprot
Q3TMB4
resolver
uniprot
Q8C3S8
resolver
uniprot
Q8C724
resolver
uniprot
Q8K188
resolver
uniprot_entry
ABHDA_MOUSE
resolver
uniprot_sec
Q3TMB4
resolver
uniprot_sec
Q8C3S8
resolver
uniprot_sec
Q8C724
resolver
uniprot_sec
Q8K188
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by palmostatin-B. {ECO:0000250|UniProtKB:Q9NUJ1}.
uniprot
proteins
amino_acid_sequence
MAAWAPCRRWGWAAVSFGRHPGLSASLARKPPRAWWLSACRQKASLSFLNRSELPNLAYKRLKGKTPGIIFIPGYLSNMNGIKAVAVEEFCKSLGHAFIRFDYSGIGSSDGNLAECTVGKWRKDVLSILDDVAEGPQILVGSSLGGWLMLHAAIARPEKVIALIGIATAADGLVTQYHALPVETQKEIEMKGEWTLPSRYNKEGYFRIPYSFIKEAEHHCLLHSPIPVTCPVRLLHGMKDEIVPWQRSLQVADRIVSPDVDVILRKQGDHRMKEKADIHLLICTIDDLIDKLSTVVP
uniprot
proteins
ec_number
3.1.1.93
uniprot
proteins
ec_number
3.1.2.22
uniprot
proteins
function
FUNCTION: Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins (PubMed:31740833). Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability (PubMed:31740833). Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate (By similarity). {ECO:0000250|UniProtKB:Q9NUJ1, ECO:0000269|PubMed:31740833}.
uniprot
proteins
mass_dalton
33040
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
31740833
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9NUJ1}.
uniprot
proteins