OSTN
entrez
344901
canonical
uniprot
P61366
canonical
ensembl
ENSG00000188729
resolver
ensp
ENSP00000508312
resolver
enst
ENST00000682035
resolver
genesymbol
OSTN
resolver
hgnc
HGNC:29961
resolver
uniprot
A1A4U3
resolver
uniprot_entry
OSTN_HUMAN
resolver
uniprot_sec
A1A4U3
resolver
amino_acid_sequence
MLDWRLASAHFILAVTLTLWSSGKVLSVDVTTTEAFDSGVIDVQSTPTVREEKSATDLTAKLLLLDELVSLENDVIETKKKRSFSGFGSPLDRLSAGSVDHKGKQRKVVDHPKRRFGIPMDRIGRNRLSNSRG
uniprot
proteins
function
FUNCTION: Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity). {ECO:0000250|UniProtKB:P61364, ECO:0000269|PubMed:27830782}.
uniprot
proteins
mass_dalton
14722
uniprot
proteins
protein_family
Osteocrin family
uniprot
proteins
pubmed
14523025
uniprot
proteins
pubmed
15044443
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15923362
uniprot
proteins
pubmed
27830782
uniprot
proteins
sequence_length
133
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:14523025}.
uniprot
proteins