GPHA2
entrez
170589
canonical
uniprot
Q96T91
canonical
ensembl
ENSG00000149735
resolver
ensp
ENSP00000279168
resolver
ensp
ENSP00000432918
resolver
enst
ENST00000279168
resolver
enst
ENST00000533257
resolver
genesymbol
GPHA2
resolver
genesymbol_syn
GPA2
resolver
genesymbol_syn
ZSIG51
resolver
hgnc
HGNC:18054
resolver
uniprot
Q52LE2
resolver
uniprot_entry
GPHA2_HUMAN
resolver
uniprot_sec
Q52LE2
resolver
amino_acid_sequence
MPMASPQTLVLYLLVLAVTEAWGQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY
uniprot
proteins
function
FUNCTION: Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production (PubMed:12045258). Plays a central role in controlling thyroid cell metabolism (PubMed:12045258). {ECO:0000269|PubMed:12045258}.
uniprot
proteins
mass_dalton
14163
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000269|PubMed:12045258}.
uniprot
proteins
protein_family
Glycoprotein hormones subunit alpha family
uniprot
proteins
pubmed
12045258
uniprot
proteins
pubmed
12089349
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
129
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins