CHRM1
entrez
1128
canonical
uniprot
P11229
canonical
ensembl
ENSG00000168539
resolver
ensp
ENSP00000306490
resolver
ensp
ENSP00000526846
resolver
genesymbol
CHRM1
resolver
hgnc
HGNC:1950
resolver
uniprot
Q53XZ3
resolver
uniprot
Q96RH1
resolver
uniprot_entry
ACM1_HUMAN
resolver
uniprot_entry
Q53XZ3_HUMAN
resolver
uniprot_sec
Q96RH1
resolver
amino_acid_sequence
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
uniprot
proteins
function
FUNCTION: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
uniprot
proteins
mass_dalton
51421
uniprot
proteins
protein_family
CHRM1 sub-subfamily
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
protein_family
Muscarinic acetylcholine receptor subfamily
uniprot
proteins
pubmed
1445347
uniprot
proteins
pubmed
15086532
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
21056967
uniprot
proteins
pubmed
2336407
uniprot
proteins
pubmed
32646996
uniprot
proteins
pubmed
3443095
uniprot
proteins
pubmed
3697105
uniprot
proteins
sequence_length
460
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 23..48; /note="Helical; Name=1"; /evidence="ECO:0000269|PubMed:32646996, ECO:0007744|PDB:6WJC"; TRANSMEM 63..84; /note="Helical; Name=2"; /evidence="ECO:0000269|PubMed:32646996, ECO:0007744|PDB:6WJC"; TRANSMEM 96..121; /note="Helical; Name=3"; /evidence="ECO:0000269|PubMed:32646996, ECO:0007744|PDB:6WJC"; TRANSMEM 143..164; /note="Helical; Name=4"; /evidence="ECO:0000269|PubMed:32646996, ECO:0007744|PDB:6WJC"; TRANSMEM 186..209; /note="Helical; Name=5"; /evidence="ECO:0000269|PubMed:32646996, ECO:0007744|PDB:6WJC"; TRANSMEM 367..390; /note="Helical; Name=6"; /evidence="ECO:0000269|PubMed:32646996, ECO:0007744|PDB:6WJC"; TRANSMEM 398..420; /note="Helical; Name=7"; /evidence="ECO:0000269|PubMed:32646996, ECO:0007744|PDB:6WJC
uniprot
proteins