HSF5
entrez
124535
canonical
uniprot
Q4G112
canonical
ensembl
ENSG00000176160
resolver
ensp
ENSP00000313243
resolver
genesymbol
HSF5
resolver
genesymbol_syn
HSTF5
resolver
hgnc
HGNC:26862
resolver
uniprot
Q08EH7
resolver
uniprot
Q8N7V2
resolver
uniprot_entry
HSF5_HUMAN
resolver
uniprot_sec
Q08EH7
resolver
uniprot_sec
Q8N7V2
resolver
amino_acid_sequence
MEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGEGLLIDQPLFEAELLSPPGPGGGGGTAGAGAEPELFKTTSFTSFIRQLNLYGFRKVVLGGPGGGKPAGNGPLHHFHNPHFRRDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNRFQRLLITSASAATAPLQHQQPPPPAGPRPEPHGPVAVGQFHRSFRRDSLSPYSCVSTPSHDHSTYPLKGLDRTPVPHRIWQNSLGMHPGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSTTSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSPTHMDALSSCVTPTASSYAHCNYFQNPSMQSSYPVEFLPSNWPCSTTDENTKTEVNLEAVFQIVDELHSSPKLEMVKVEPVENQCPTSPSYRGQHILANSNNSNPCSASQASQLEPLTPVGSDIMSFVVGTEQAVACSLPQSPEYIYTIHTAQPVENSTIQESAAIQQAHVKLKEHLNHNPSPSSVVFVQEGPPFSTHQVDANIKCQTSSRENILPSEQMGFLISEMGPASKPSEDTGLATPARYREHRSNSQQGKSPDLHLLVDVACKQERFPKEEELKE
uniprot
proteins
function
FUNCTION: DNA-binding transcription factor that is essential for male fertility, spermatogenesis and meiotic prophase progression in spermatocytes under non-stress conditions. Positvely and negatively regulates gene expression to ensure progression of meiotic prophase beyond pachytene stage in spermatocytes. {ECO:0000250|UniProtKB:Q5ND04}.
uniprot
proteins
mass_dalton
65265
uniprot
proteins
protein_family
HSF family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
sequence_length
596
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q5ND04}. Chromosome {ECO:0000250|UniProtKB:Q5ND04}. Note=Expressed primarily in the XY body of pachytene spermatocytes. {ECO:0000250|UniProtKB:Q5ND04}.
uniprot
proteins