Lpo
entrez
76113
canonical
uniprot
Q5SW46
canonical
ensembl
ENSMUSG00000009356
resolver
ensp
ENSMUSP00000099466
resolver
ensp
ENSMUSP00000197314
resolver
enst
ENSMUST00000103177
resolver
genesymbol
Lpo
resolver
uniprot_entry
PERL_MOUSE
resolver
amino_acid_sequence
MKVLLHLPALLASLTLLQTAASASDDPTAETDIIHDTVEEVKVWVNKAFLDSRDRLKMAMTTKIHSTRHLSDYLKHAKGRTRTAIRSGQVWEESLKKLSQFLTNVTGQGLDLTLLSWEAGCDPPAPTMTCNISSPYRTITGYCNNRKNPALGSANRALARWLPAEYEDGLSLPYGWTPGKMRNGFPLPQPREVSNQIAAYLNEEDVLDQKRSMLFMQWGQIVDHDMDFAPETEMGSDTYTKAQCDEHCIQGDNCFPIMFPPGDPKLKTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASLVYSPEPSLANRLRNLSSPLGLMAVNEEVSDNGRPFPPFVKMKPSPCEVINATAGVPCFLAGDSRASEQILLATSHTLFIREHNRLATELSRLNPHWDRETLYQEARKIMGAFIQITTFRDYLPILLGDEMQKWIPPYQGYNESVDPRISNVFTFALRFGHLEIPSTVYRLDENYQPWGSESELPLHTVFFNTWRLVKDGGIDPLVRGLLAKNAKLMHQNKMMTGELRNKLFQPNHTIHGFDLASINIQRSRDHGQPGYNSWRAFCGLSQPKTLEELSAVMKNEVLAKKLMDLYGTPSNIDIWLGAVAEPLVHRGRVGPLLTCLLGQQFQRIRDGDRFWWENPGVFTEKQRESLQKMSFSRLVCDNTGIDKVPLNPFQANAYPHGFVDCSSIDKLDLSPWASVKE
uniprot
proteins
ec_number
1.11.1.7
uniprot
proteins
function
FUNCTION: Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2) (By similarity). Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2 (By similarity). Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism (By similarity). May be implicated in airway host defense against infection (By similarity). May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation (PubMed:34127712). {ECO:0000250|UniProtKB:P22079, ECO:0000250|UniProtKB:P80025, ECO:0000269|PubMed:34127712}.
uniprot
proteins
mass_dalton
80124
uniprot
proteins
protein_family
Peroxidase family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22343415
uniprot
proteins
pubmed
34127712
uniprot
proteins
sequence_length
710
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P22079}. Cytoplasm {ECO:0000269|PubMed:22343415}. Note=Expressed in the cytoplasm in intestinal epithelial cells. {ECO:0000269|PubMed:22343415}.
uniprot
proteins