GNG2
entrez
54331
canonical
uniprot
P59768
canonical
ensembl
ENSG00000186469
resolver
ensp
ENSP00000334448
resolver
ensp
ENSP00000451102
resolver
ensp
ENSP00000451231
resolver
ensp
ENSP00000451576
resolver
ensp
ENSP00000452014
resolver
ensp
ENSP00000484021
resolver
ensp
ENSP00000559689
resolver
ensp
ENSP00000559690
resolver
ensp
ENSP00000559691
resolver
ensp
ENSP00000559692
resolver
ensp
ENSP00000559693
resolver
ensp
ENSP00000559694
resolver
ensp
ENSP00000559695
resolver
ensp
ENSP00000608480
resolver
ensp
ENSP00000608481
resolver
ensp
ENSP00000608482
resolver
ensp
ENSP00000624571
resolver
ensp
ENSP00000624572
resolver
ensp
ENSP00000772640
resolver
enst
ENST00000335281
resolver
enst
ENST00000554736
resolver
enst
ENST00000555472
resolver
enst
ENST00000556752
resolver
enst
ENST00000556766
resolver
enst
ENST00000615906
resolver
enst
ENST00000889630
resolver
enst
ENST00000889631
resolver
enst
ENST00000889632
resolver
enst
ENST00000889633
resolver
enst
ENST00000889634
resolver
enst
ENST00000889635
resolver
enst
ENST00000889636
resolver
enst
ENST00000938421
resolver
enst
ENST00000938422
resolver
enst
ENST00000938423
resolver
enst
ENST00000954512
resolver
enst
ENST00000954513
resolver
genesymbol
GNG2
resolver
hgnc
HGNC:4404
resolver
uniprot
Q5JPE2
resolver
uniprot
Q6P9A9
resolver
uniprot_entry
GBG2_HUMAN
resolver
uniprot_sec
Q5JPE2
resolver
uniprot_sec
Q6P9A9
resolver
amino_acid_sequence
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL
uniprot
proteins
function
FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems (PubMed:29925951, PubMed:33762731, PubMed:34239069, PubMed:35610220, PubMed:35714614, PubMed:35835867, PubMed:36087581, PubMed:36989299, PubMed:37327704, PubMed:37935376, PubMed:37935377, PubMed:37963465, PubMed:38168118, PubMed:38552625, PubMed:39103320). The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (PubMed:29925951, PubMed:33762731, PubMed:34239069, PubMed:35610220, PubMed:35714614, PubMed:35835867, PubMed:36087581, PubMed:36989299, PubMed:37327704, PubMed:37935376, PubMed:37935377, PubMed:37963465, PubMed:38168118, PubMed:38552625, PubMed:39103320). Involved in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction (PubMed:40339580, PubMed:38600377, PubMed:38776963). {ECO:0000269|PubMed:29925951, ECO:0000269|PubMed:33762731, ECO:0000269|PubMed:34239069, ECO:0000269|PubMed:35610220, ECO:0000269|PubMed:35714614, ECO:0000269|PubMed:35835867, ECO:0000269|PubMed:36087581, ECO:0000269|PubMed:36989299, ECO:0000269|PubMed:37327704, ECO:0000269|PubMed:37935376, ECO:0000269|PubMed:37935377, ECO:0000269|PubMed:37963465, ECO:0000269|PubMed:38168118, ECO:0000269|PubMed:38552625, ECO:0000269|PubMed:38600377, ECO:0000269|PubMed:38776963, ECO:0000269|PubMed:39103320, ECO:0000269|PubMed:40339580}.
uniprot
proteins
mass_dalton
7850
uniprot
proteins
protein_family
G protein gamma family
uniprot
proteins
pubmed
10833460
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18611381
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19713215
uniprot
proteins
pubmed
21827955
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
28219978
uniprot
proteins
pubmed
29925951
uniprot
proteins
pubmed
33762731
uniprot
proteins
pubmed
33828102
uniprot
proteins
pubmed
34239069
uniprot
proteins
pubmed
35027551
uniprot
proteins
pubmed
35061538
uniprot
proteins
pubmed
35418677
uniprot
proteins
pubmed
35418678
uniprot
proteins
pubmed
35418679
uniprot
proteins
pubmed
35418682
uniprot
proteins
pubmed
35501348
uniprot
proteins
pubmed
35610220
uniprot
proteins
pubmed
35714614
uniprot
proteins
pubmed
35835867
uniprot
proteins
pubmed
35982227
uniprot
proteins
pubmed
36087581
uniprot
proteins
pubmed
36171289
uniprot
proteins
pubmed
36989299
uniprot
proteins
pubmed
37327704
uniprot
proteins
pubmed
37935376
uniprot
proteins
pubmed
37935377
uniprot
proteins
pubmed
37963465
uniprot
proteins
pubmed
38168118
uniprot
proteins
pubmed
38552625
uniprot
proteins
pubmed
38600377
uniprot
proteins
pubmed
38776963
uniprot
proteins
pubmed
39103320
uniprot
proteins
pubmed
39833471
uniprot
proteins
pubmed
40339580
uniprot
proteins
sequence_length
71
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins