BCO2
entrez
83875
canonical
uniprot
Q9BYV7
canonical
ensembl
ENSG00000197580
resolver
ensp
ENSP00000350314
resolver
ensp
ENSP00000354338
resolver
ensp
ENSP00000414843
resolver
ensp
ENSP00000431802
resolver
ensp
ENSP00000436615
resolver
genesymbol
BCO2
resolver
genesymbol_syn
BCDO2
resolver
hgnc
HGNC:18503
resolver
uniprot
B0YIX5
resolver
uniprot
B2RCV8
resolver
uniprot
B4DNC3
resolver
uniprot
E9PBI8
resolver
uniprot
E9PJJ1
resolver
uniprot
Q8IUS0
resolver
uniprot
Q96JC8
resolver
uniprot
Q96JY5
resolver
uniprot_entry
B2RCV8_HUMAN
resolver
uniprot_entry
BCDO2_HUMAN
resolver
uniprot_sec
B0YIX5
resolver
uniprot_sec
B4DNC3
resolver
uniprot_sec
E9PBI8
resolver
uniprot_sec
E9PJJ1
resolver
uniprot_sec
Q8IUS0
resolver
uniprot_sec
Q96JC8
resolver
uniprot_sec
Q96JY5
resolver
amino_acid_sequence
MFFRVFLHFIRSHSATAVDFLPVMVHRLPVFKRYMGNTPQKKAVFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKDKYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNVFERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKFIAVNGATAHPHYDLDGTAYNMGNSFGPYGFSYKVIRVPPEKVDLGETIHGVQVICSIASTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSKIRGKAFSDGISWEPQCNTRFHVVEKRTGQLLPGRYYSKPFVTFHQINAFEDQGCVIIDLCCQDNGRTLEVYQLQNLRKAGEGLDQVHNSAAKSFPRRFVLPLNVSLNAPEGDNLSPLSYTSASAVKQADGTIWCSHENLHQEDLEKEGGIEFPQIYYDRFSGKKYHFFYGCGFRHLVGDSLIKVDVVNKTLKVWREDGFYPSEPVFVPAPGTNEEDGGVILSVVITPNQNESNFILVLDAKNFEELGRAEVPVQMPYGFHGTFIPI
uniprot
proteins
ec_number
1.13.11.-
uniprot
proteins
ec_number
1.13.11.71
uniprot
proteins
function
FUNCTION: Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules. {ECO:0000250|UniProtKB:Q99NF1}.
uniprot
proteins
mass_dalton
65674
uniprot
proteins
protein_family
Carotenoid oxygenase family
uniprot
proteins
pubmed
11278918
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15983114
uniprot
proteins
pubmed
16554811
uniprot
proteins
sequence_length
579
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q99NF1}.
uniprot
proteins