Tmem38b
entrez
362521
canonical
uniprot
Q68FV1
canonical
ensembl
ENSRNOG00000028063
resolver
ensembl
ENSRNOG00055019359
resolver
ensembl
ENSRNOG00060006001
resolver
ensembl
ENSRNOG00065014874
resolver
ensp
ENSRNOP00000033050
resolver
ensp
ENSRNOP00055026751
resolver
ensp
ENSRNOP00060007452
resolver
ensp
ENSRNOP00065019193
resolver
enst
ENSRNOT00000034570
resolver
enst
ENSRNOT00055033023
resolver
enst
ENSRNOT00060009929
resolver
enst
ENSRNOT00065024599
resolver
genesymbol
Tmem38b
resolver
uniprot_entry
TM38B_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Channel activity is activated by increased cytosolic Ca(2+) levels and blocked by luminal high Ca(2+) levels. {ECO:0000250|UniProtKB:Q6GN30}.
uniprot
proteins
amino_acid_sequence
MEYPWDDLTLAFSRTSMFPFFDIAHYLVSVMALKQRPGAVAAAWSNPLSSWLSAMLHCFGGGILSCILLAEPPLKFLTNHTNILLASSIWYIVFFCPRDLVSQGYSYQPIQLLAAGMKEVTRTWKIVGGVAHANGYYRNGWIVMIAVGWARGAGGAIITACEQLLKGDWKPEGDEWLKMSFPCKVTLLGSIMFTFQHTRHLAISKHDLMFLYTIFLVTIKVTMMMTKDAAVTLTPFEDTLTRMLFGRQQQQFSLSEKKAEVKPSSNGSASSASKRGTEPPSSAKRHAKKED
uniprot
proteins
function
FUNCTION: Intracellular monovalent cation channel required for maintenance of rapid intracellular calcium release. Acts as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. Activated by increased cytosolic Ca(2+) levels. {ECO:0000250|UniProtKB:Q6GN30}.
uniprot
proteins
mass_dalton
32445
uniprot
proteins
protein_family
TMEM38 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9DAV9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9DAV9}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..33; /note="Helical;Name=1"; /evidence="ECO:0000255"; TRANSMEM 48..69; /note="Helical;Name=2"; /evidence="ECO:0000255"; TRANSMEM 81..99; /note="Helical;Name=3"; /evidence="ECO:0000255"; TRANSMEM 104..122; /note="Helical;Name=4"; /evidence="ECO:0000255"; TRANSMEM 139..156; /note="Helical;Name=5"; /evidence="ECO:0000255"; TRANSMEM 180..197; /note="Helical;Name=6"; /evidence="ECO:0000255"; TRANSMEM 207..225; /note="Helical;Name=7"; /evidence="ECO:0000255
uniprot
proteins