Pomk
entrez
306549
canonical
uniprot
Q4V8A9
canonical
ensembl
ENSRNOG00000014628
resolver
ensembl
ENSRNOG00055007645
resolver
ensembl
ENSRNOG00060012257
resolver
ensembl
ENSRNOG00065002739
resolver
ensp
ENSRNOP00000019630
resolver
ensp
ENSRNOP00055010203
resolver
ensp
ENSRNOP00060016380
resolver
ensp
ENSRNOP00065002615
resolver
enst
ENSRNOT00000019630
resolver
enst
ENSRNOT00055012799
resolver
enst
ENSRNOT00060020785
resolver
enst
ENSRNOT00065003737
resolver
genesymbol
Pomk
resolver
genesymbol_syn
Sgk196
resolver
uniprot_entry
SG196_RAT
resolver
amino_acid_sequence
MGQQHGARNGLTHRELPRGMGLLLAMALMNVVLYVCLDHLFISPGRATEDPRRCPPGYFRMGRMRNCSRWLSCEELRTEVRQLKLVGEGAVKRVFLSEWNEHKVALSRLTRLEMKEDFLHGLRMLTSLQSQHVVTLAGFCEEDGTILTEYHPLGSLSNLEETLNLSKYRDVNTWQHRLRLAVEYVSIINYLHHSPLGTRVMCDSNDLPKTLSQYLLTSNFSIVANDLDALPLVDHGSRVLVKCGHRELHGDFVAPEQLWPYGEDTPFQDDLMPPYDEKIDIWKIPDVSSFLLGHVEGSDMVRFHLFDIHKACKNQFPAERPTAQNVLDAYQKVFHSLRDTVMSQTKEML
uniprot
proteins
ec_number
2.7.1.183
uniprot
proteins
function
FUNCTION: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
40054
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
STKL subfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
349
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..42; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins