Ado
entrez
211488
canonical
uniprot
Q6PDY2
canonical
ensembl
ENSMUSG00000057134
resolver
ensp
ENSMUSP00000075107
resolver
enst
ENSMUST00000075686
resolver
genesymbol
Ado
resolver
genesymbol_syn
Gm237
resolver
uniprot
Q3U2E1
resolver
uniprot_entry
AEDO_MOUSE
resolver
uniprot_sec
Q3U2E1
resolver
amino_acid_sequence
MPRDNMASLIQRIARQACLTFRGSSTGSEGPAPGFPENLSLLKSLLTQVRAEDLNIAPRKALPQPLPRNLPPVTYMHIYETEGFSLGVFLLKSGTCIPLHDHPGMHGMLKVLYGTVRISCMDKLDTGAGHRRPPPEQQFEPPLQPLEREAVRPGVLRSRAEYTEASGPCVLTPHRDNLHQIDAVDGPAAFLDILAPPYDPEDGRDCHYYRVVEPIRPKEASGSACDLPREVWLLETPQADDFWCEGEPYPGPKVLP
uniprot
proteins
ec_number
1.13.11.19
uniprot
proteins
function
FUNCTION: Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate (PubMed:17581819, PubMed:32601061). Catalyzes the oxidation of cysteamine (2-aminoethanethiol) to hypotaurine (PubMed:17581819, PubMed:32601061). Catalyzes the oxidation of the regulator of G protein signaling 5 (RGS5) (PubMed:32601061). Also oxidizes proteins RGS4 and interleukin-32 (IL32) (By similarity). {ECO:0000250|UniProtKB:Q96SZ5, ECO:0000269|PubMed:17581819, ECO:0000269|PubMed:32601061}.
uniprot
proteins
mass_dalton
28372
uniprot
proteins
mutagenesis
MUTAGEN 102; /note="H->A: Loss of enzyme activity and iron incorporation."; /evidence="ECO:0000269|PubMed:17581819
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17581819
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
32601061
uniprot
proteins
pubmed
34762398
uniprot
proteins
sequence_length
256
uniprot
proteins