Mzb1
entrez
291675
canonical
uniprot
Q561R0
canonical
ensembl
ENSRNOG00000022009
resolver
ensembl
ENSRNOG00055023460
resolver
ensembl
ENSRNOG00060026770
resolver
ensembl
ENSRNOG00065012805
resolver
ensp
ENSRNOP00000030810
resolver
ensp
ENSRNOP00055032763
resolver
ensp
ENSRNOP00060038525
resolver
ensp
ENSRNOP00065016125
resolver
enst
ENSRNOT00000036301
resolver
enst
ENSRNOT00055040324
resolver
enst
ENSRNOT00060046362
resolver
enst
ENSRNOT00065020920
resolver
genesymbol
Mzb1
resolver
genesymbol_syn
Pacap
resolver
uniprot_entry
MZB1_RAT
resolver
amino_acid_sequence
MRLPLPLLLLFGCRAILGSFGDRVSLSATAPTLDDEEKYASHMPTHLRCDACRAVAYQMGQHLAKAEAKSHTPDSSGSQELSESTYTDVLDRTCSQNWQSYGVQEVNQMKRLMGPGLSKGPEPSISVMITGGPWPNRLSMTCFHYLGEFGEDQIYEAYRQGHETLEALLCGGTHGSCSQEIPAQREEL
uniprot
proteins
function
FUNCTION: Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion, and integrin activation. {ECO:0000250}.; FUNCTION: Acts as a hormone-regulated adipokine/pro-inflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
20712
uniprot
proteins
post_translational_modification
PTM: Forms an interchain disulfide bond with IgM monomers. {ECO:0000250}.
uniprot
proteins
protein_family
MZB1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
188
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000250|UniProtKB:Q8WU39, ECO:0000255|PROSITE-ProRule:PRU10138}. Secreted {ECO:0000250|UniProtKB:Q8WU39}.
uniprot
proteins