Btbd10
entrez
68815
canonical
uniprot
Q80X66
canonical
ensembl
ENSMUSG00000038187
resolver
ensp
ENSMUSP00000048530
resolver
ensp
ENSMUSP00000113496
resolver
ensp
ENSMUSP00000113632
resolver
ensp
ENSMUSP00000225427
resolver
ensp
ENSMUSP00000362351
resolver
enst
ENSMUST00000047091
resolver
enst
ENSMUST00000117577
resolver
enst
ENSMUST00000119278
resolver
genesymbol
Btbd10
resolver
genesymbol_syn
Gmrp1
resolver
uniprot
E9Q6L8
resolver
uniprot
E9Q6Y9
resolver
uniprot_entry
BTBDA_MOUSE
resolver
uniprot_entry
E9Q6L8_MOUSE
resolver
uniprot_entry
E9Q6Y9_MOUSE
resolver
amino_acid_sequence
MAGRPHPYDSNSSDPENWDRKLHSRPRKLYKHSSSASRVAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQHHIEREKDHSSSRPSSPRPQRASPNGSMSSAGNSSRNSSQSSSDGSCKTSGEMVFVYENAKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPSHPASGNNDLDPDAQNPML
uniprot
proteins
function
FUNCTION: Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells. {ECO:0000269|PubMed:18160256, ECO:0000269|PubMed:21267538}.
uniprot
proteins
mass_dalton
53772
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18160256
uniprot
proteins
pubmed
21267538
uniprot
proteins
pubmed
24156551
uniprot
proteins
sequence_length
475
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9BSF8}. Cytoplasm {ECO:0000269|PubMed:18160256}. Note=Colocalizes with KCTD20 in filamentous structures. {ECO:0000269|PubMed:24156551}.
uniprot
proteins