Polrmt
entrez
216151
canonical
uniprot
Q8BKF1
canonical
ensembl
ENSMUSG00000020329
resolver
ensp
ENSMUSP00000020580
resolver
ensp
ENSMUSP00000124936
resolver
enst
ENSMUST00000020580
resolver
enst
ENSMUST00000159016
resolver
genesymbol
Polrmt
resolver
uniprot
E9PWD9
resolver
uniprot
Q3U3J3
resolver
uniprot
Q3V3C0
resolver
uniprot
Q8BJE0
resolver
uniprot_entry
E9PWD9_MOUSE
resolver
uniprot_entry
Q3U3J3_MOUSE
resolver
uniprot_entry
Q3V3C0_MOUSE
resolver
uniprot_entry
RPOM_MOUSE
resolver
uniprot_sec
Q8BJE0
resolver
amino_acid_sequence
MSALRWTRSAAGLGRVLRSPGPHRPPSEEGTFGGFCSSRRSSAASPREQHVLREWGHAELLEVLEARVRQLRAEGTPEMRVKKVQVDRPPQGHSSRWAQKLEAEKRVKQRRQKEVDQQKQALTQEFWTLHKEPKIWNKKLAGYLQPSKKGTPTNSEEKQLAQALQAALGRLSSREAEALARKKAKAVEAQILVLQQKFLAFFECCVCTGQVPLAHHVLVTHHNNGDRQQVLTLHMYNTVMLGWARKGSFRELVYVFLMLKDAGLSPDLCSYAAALQCMGRRDQDVRTIQRCLKQMMEEGFQPQLLFTDLVLEEEDRAALLRAVVKAEPAFRPPPQAPSPVNTSTLLKDIYSKEGPVSYPKLHLPLDTLQDLFYQQLHVELSSSVCVQSVEKAPVMSKEVIEARKTLQALREQWEVELLRVLRETKATMGRQAYEGQPTLYPFLCLLSEGEFVSILMQVLKVLPAQGEPLIQLAHNLGLRVLNRHLVKQKQVTNHVQKLGQRYSQYLQLLASDTQVAPCLPREYWESLGPLEAPAQQPWSVPVLLQLGKQLAELLVQAVQMPRSLAARQGAQRSIPVLYHVYSFRSYRQVGILKPHPAFTHLLETAAEPTLTFETTEVPMLCPPLPWTSLHSGAYLLSSTKLMRATEGTTQHQRLLEQCPPAQLHGPLDALTQLGNCAWRVNGHLLDLVLQIFRDKGCMPLGVPPPRSEAPRPARYQLPPGSTPVHKSELRKELARCLKVAREMHSLRSEALYRLSLAQHLRHRVFWLPHNMDFRGRTYPCPPHFNHLGSDLARALLEFAEGRPLGPRGLDWLKIHLINLTGLKKGDSLRMRLAFADEVMEEILDSADNPLTGRKWWMEADEPWQTLACCMEVAHAVRSPDPAAYISHLPVHQDGSCNGLQHYAALGRDSVGAASVNLTPSDLPQDVYREVATQVEEFRQQDAKEGLRVAQVLEGFISRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFTSTRAIQHWLTESANLISHAGWPVEWVTPLGIPIIQPYHRESKVQVKGGLQSITLTSSVDESQKPNTLKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLIFVSVHDCFWTHAADIPTMNEVCREQFVRLHSQPILEDLAKFLKKRFCSVSSIKSLKSSERALVTKLQETLQSLPKTGTFDLGQVIRSTYFFS
uniprot
proteins
ec_number
2.7.7.6
uniprot
proteins
function
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Has DNA primase activity. Catalyzes the synthesis of short RNA primers that are necessary for the initiation of lagging-strand DNA synthesis from the origin of light-strand DNA replication (OriL). {ECO:0000250|UniProtKB:O00411}.
uniprot
proteins
mass_dalton
136705
uniprot
proteins
protein_family
Phage and mitochondrial RNA polymerase family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23283301
uniprot
proteins
sequence_length
1207
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:23283301}.
uniprot
proteins