Msi1
entrez
17690
canonical
uniprot
Q61474
canonical
ensembl
ENSMUSG00000054256
resolver
ensp
ENSMUSP00000070415
resolver
ensp
ENSMUSP00000120516
resolver
ensp
ENSMUSP00000143900
resolver
ensp
ENSMUSP00000144032
resolver
ensp
ENSMUSP00000166449
resolver
ensp
ENSMUSP00000166450
resolver
genesymbol
Msi1
resolver
genesymbol_syn
Msi1h
resolver
uniprot
Q8BNC7
resolver
uniprot_entry
MSI1H_MOUSE
resolver
uniprot_sec
Q8BNC7
resolver
amino_acid_sequence
METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERSPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH
uniprot
proteins
function
FUNCTION: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. {ECO:0000269|PubMed:11359897, ECO:0000269|PubMed:12407178}.
uniprot
proteins
mass_dalton
39119
uniprot
proteins
mutagenesis
MUTAGEN 63; /note="F->L: Abolishes RNA binding; when associated with L-65 and L-68."; /evidence="ECO:0000269|PubMed:11359897"; MUTAGEN 65; /note="F->L: Abolishes RNA binding; when associated with L-63 and L-68."; /evidence="ECO:0000269|PubMed:11359897"; MUTAGEN 68; /note="F->L: Abolishes RNA binding; when associated with L-63 and L-65."; /evidence="ECO:0000269|PubMed:11359897
uniprot
proteins
protein_family
Musashi family
uniprot
proteins
pubmed
10080895
uniprot
proteins
pubmed
11359897
uniprot
proteins
pubmed
12407178
uniprot
proteins
pubmed
12907678
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16554442
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8660864
uniprot
proteins
sequence_length
362
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16554442}. Nucleus {ECO:0000269|PubMed:16554442}.
uniprot
proteins