Ssx2ip
entrez
99167
canonical
uniprot
Q8VC66
canonical
ensembl
ENSMUSG00000036825
resolver
ensp
ENSMUSP00000045663
resolver
ensp
ENSMUSP00000101755
resolver
ensp
ENSMUSP00000101757
resolver
ensp
ENSMUSP00000101759
resolver
ensp
ENSMUSP00000213864
resolver
ensp
ENSMUSP00000213865
resolver
ensp
ENSMUSP00000213866
resolver
ensp
ENSMUSP00000213869
resolver
ensp
ENSMUSP00000213872
resolver
ensp
ENSMUSP00000213881
resolver
ensp
ENSMUSP00000213882
resolver
ensp
ENSMUSP00000213890
resolver
ensp
ENSMUSP00000342905
resolver
enst
ENSMUST00000039021
resolver
enst
ENSMUST00000106149
resolver
enst
ENSMUST00000106151
resolver
enst
ENSMUST00000106153
resolver
genesymbol
Ssx2ip
resolver
uniprot
A0A0R4J1A9
resolver
uniprot
Q8BG59
resolver
uniprot
Q8C7X0
resolver
uniprot
Q8K2F7
resolver
uniprot_entry
A0A0R4J1A9_MOUSE
resolver
uniprot_entry
ADIP_MOUSE
resolver
uniprot_sec
Q8BG59
resolver
uniprot_sec
Q8C7X0
resolver
uniprot_sec
Q8K2F7
resolver
amino_acid_sequence
MGDWMTVTDPVLCTENKNLSQYTSETKMSPSSLYSQQVLCSSVPLSKNVHGVFGVFCTGENIEQSISYLDQELTTFGFPSLYEESKSKEAKRELNIVAVLNCMNELLVLQRKNLLAQESVETQNLKLGSDMDHLQSCYAKLKEQLETSRREMIGLQERDRQLQCKNRSLHQLLKNEKDEVQKLQNIIASRATQYNHDVKRKEREYNKLKERLHQLVMNKKDKNIAMDVLNYVGRADGKRGSWRTDKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERAEDGTGTVAISDIEDDSGELSRDSVWGLSCDTVREQLTNSIRKQWRILKSHVEKLDNQASKVHSEGLNEEDVISRQDHEQETEKLELEIERCKEMIKAQQQLLQQQLATTCDDDTTSLLRDCYLLEEKERLKEEWTLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWVKQQFLNMTNFDHQNSENVKLFSAFSGSSDPDNLIVHSRPRQKKLHSVANGVPACTSKLTKSLPASPSTSDFRQTHSCVSEHSSISVLNITPEESKPSEVARESTDQKWSVQSRPSSREGCYSGCSSAFRSAHGDRDDLP
uniprot
proteins
function
FUNCTION: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (PubMed:12446711). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (PubMed:22027834). Involved in ciliogenesis (By similarity). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (By similarity). {ECO:0000250|UniProtKB:Q9Y2D8, ECO:0000269|PubMed:12446711, ECO:0000269|PubMed:22027834}.
uniprot
proteins
mass_dalton
70956
uniprot
proteins
protein_family
ADIP family
uniprot
proteins
pubmed
12446711
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22027834
uniprot
proteins
pubmed
24356449
uniprot
proteins
sequence_length
615
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, adherens junction {ECO:0000269|PubMed:12446711}. Nucleus {ECO:0000250|UniProtKB:Q9Y2D8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:24356449}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:24356449}. Note=Not found at cell-matrix AJs.
uniprot
proteins