HINT3
entrez
135114
canonical
uniprot
Q9NQE9
canonical
ensembl
ENSG00000111911
resolver
ensp
ENSP00000229633
resolver
enst
ENST00000229633
resolver
genesymbol
HINT3
resolver
hgnc
HGNC:18468
resolver
uniprot
B3KQ91
resolver
uniprot
Q8N0Y9
resolver
uniprot_entry
HINT3_HUMAN
resolver
uniprot_sec
B3KQ91
resolver
uniprot_sec
Q8N0Y9
resolver
amino_acid_sequence
MAEEQVNRSAGLAPDCEASATAETTVSSVGTCEAAGKSPEPKDYDSTCVFCRIAGRQDPGTELLHCENEDLICFKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELVENMVTVGKTILERNNFTDFTNVRMGFHMPPFCSISHLHLHVLAPVDQLGFLSKLVYRVNSYWFITADHLIEKLRT
uniprot
proteins
ec_number
3.9.1.-
uniprot
proteins
function
FUNCTION: Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:17870088). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase (PubMed:17870088). Hydrolyzes 3-indolepropionic acyl-adenylate and fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed:17870088). {ECO:0000269|PubMed:17870088}.
uniprot
proteins
mass_dalton
20361
uniprot
proteins
mutagenesis
MUTAGEN 145; /note="H->A: Abolishes adenosine 5'-monophosphoramidase activity."; /evidence="ECO:0000269|PubMed:17870088
uniprot
proteins
protein_family
HINT family
uniprot
proteins
pubmed
12119013
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17870088
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
sequence_length
182
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17870088}. Nucleus {ECO:0000269|PubMed:17870088}. Note=Localized as aggregates in the cytoplasm and the nucleus.
uniprot
proteins