Q63245
uniprot
Q63245
canonical
amino_acid_sequence
LVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKR
uniprot
proteins
function
FUNCTION: Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator (By similarity). Negatively regulates transcription of transcriptional repressor Rhit/Zfp13 (By similarity). Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis (By similarity). {ECO:0000250|UniProtKB:Q61060, ECO:0000250|UniProtKB:Q9UJU5}.
uniprot
proteins
mass_dalton
11943
uniprot
proteins
pubmed
7683413
uniprot
proteins
pubmed
9571051
uniprot
proteins
sequence_length
101
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}.
uniprot
proteins