DPF1
entrez
8193
canonical
uniprot
Q92782
canonical
ensembl
ENSG00000011332
resolver
ensp
ENSP00000347716
resolver
ensp
ENSP00000390223
resolver
ensp
ENSP00000397354
resolver
ensp
ENSP00000411569
resolver
ensp
ENSP00000412098
resolver
ensp
ENSP00000483226
resolver
ensp
ENSP00000510614
resolver
ensp
ENSP00000550271
resolver
ensp
ENSP00000585670
resolver
ensp
ENSP00000585673
resolver
ensp
ENSP00000750680
resolver
enst
ENST00000355526
resolver
enst
ENST00000416611
resolver
enst
ENST00000420980
resolver
enst
ENST00000456296
resolver
enst
ENST00000614244
resolver
enst
ENST00000689228
resolver
genesymbol
DPF1
resolver
genesymbol_syn
BAF45B
resolver
genesymbol_syn
NEUD4
resolver
hgnc
HGNC:20225
resolver
uniprot
A0A087X0A4
resolver
uniprot
A0A804CCM0
resolver
uniprot
A0A804CYY4
resolver
uniprot
A0A8I5QL29
resolver
uniprot
B3KSY8
resolver
uniprot
C8C3P2
resolver
uniprot
E9PDV3
resolver
uniprot
J3KQY6
resolver
uniprot
Q08AJ0
resolver
uniprot
Q6PJ73
resolver
uniprot_entry
A0A087X0A4_HUMAN
resolver
uniprot_entry
A0A804CCM0_HUMAN
resolver
uniprot_entry
A0A804CYY4_HUMAN
resolver
uniprot_entry
A0A8I5QL29_HUMAN
resolver
uniprot_entry
C8C3P2_HUMAN
resolver
uniprot_entry
DPF1_HUMAN
resolver
uniprot_entry
E9PDV3_HUMAN
resolver
uniprot_entry
J3KQY6_HUMAN
resolver
uniprot_entry
Q6PJ73_HUMAN
resolver
uniprot_sec
B3KSY8
resolver
uniprot_sec
Q08AJ0
resolver
amino_acid_sequence
MATVIPGPLSLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPEGPVLEALLCAETGEKKIELKEEETIMDCQKQQLLEFPHDLEVEDLEDDIPRRKNRAKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEENAERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAYITLT
uniprot
proteins
function
FUNCTION: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
44128
uniprot
proteins
protein_family
Requiem/DPF family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
8812431
uniprot
proteins
sequence_length
387
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
uniprot
proteins