Tle2
entrez
21886
canonical
uniprot
Q9WVB2
canonical
ensembl
ENSMUSG00000034771
resolver
ensp
ENSMUSP00000117453
resolver
ensp
ENSMUSP00000121125
resolver
ensp
ENSMUSP00000121173
resolver
ensp
ENSMUSP00000298466
resolver
ensp
ENSMUSP00000298467
resolver
ensp
ENSMUSP00000298470
resolver
enst
ENSMUST00000135211
resolver
enst
ENSMUST00000146358
resolver
genesymbol
Tle2
resolver
genesymbol_syn
Grg2
resolver
genesymbol_syn
mKIAA4188
resolver
uniprot
F7AAF1
resolver
uniprot
Q3UN01
resolver
uniprot
Q5DTI7
resolver
uniprot_entry
F7AAF1_MOUSE
resolver
uniprot_entry
Q3UN01_MOUSE
resolver
uniprot_entry
Q5DTI7_MOUSE
resolver
uniprot_entry
TLE2_MOUSE
resolver
amino_acid_sequence
MYPQGRHPTPLQSGQPFKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMAAPHQCPQGGTSYPHWPRLSPLQYYEMSYGLNIEMHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNSLLGQQNQLQPLSHAPPVPLTPRPAGLVGAGATGLLALSGALAAQAQLVAAVKEDRVGVDAEGSRVDRAASRSSSPSPPESLVEEDHPSSRGGSGKQQRAEDKDLSGPYDSEEDKSDYNLVVDEDQPSEPPSPVTTPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRSCGTSPPQDSSTPGPSSASHLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSYVGLHLSPQVSSSVVYGRSPLQMAFESHPHLRGSSVSLPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGKGCVKVWDVGQPGSKTPVAQLDCLNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPEKYQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
uniprot
proteins
function
FUNCTION: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
82623
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by XIAP/BIRC4. {ECO:0000250|UniProtKB:Q04725}.
uniprot
proteins
protein_family
WD repeat Groucho/TLE family
uniprot
proteins
pubmed
11486032
uniprot
proteins
pubmed
18254933
uniprot
proteins
pubmed
23990468
uniprot
proteins
sequence_length
767
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins