Snip1
entrez
76793
canonical
uniprot
Q8BIZ6
canonical
ensembl
ENSMUSG00000050213
resolver
ensp
ENSMUSP00000060721
resolver
enst
ENSMUST00000052183
resolver
genesymbol
Snip1
resolver
uniprot
Q3V106
resolver
uniprot
Q8BIZ4
resolver
uniprot_entry
SNIP1_MOUSE
resolver
uniprot_sec
Q3V106
resolver
uniprot_sec
Q8BIZ4
resolver
amino_acid_sequence
MKAGKSERERSGRRRHRSGDALTTVVVKQERLSPEPVAHRRPDAPAASLSPPAAEPGHSGHRGSRARSPAKKKSKSSGRRSKSPRTKRSQSPHYPMVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSERDRHRGHSRQGRSSDERPVSGQDRDRDSQNLQAQEEERDFHNARRREHRQQNESAGSEAQEVIPRPAGNRSKEVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSELDRKEDEDDEEEEMVSDS
uniprot
proteins
function
FUNCTION: Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity). Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. {ECO:0000250|UniProtKB:Q8TAD8}.
uniprot
proteins
mass_dalton
44415
uniprot
proteins
post_translational_modification
PTM: Degraded by the proteasome upon binding to the SMAD1/OAZ1/PSMB4 complex. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
383
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8TAD8}.
uniprot
proteins