TARM1
entrez
441864
canonical
uniprot
B6A8C7
canonical
ensembl
ENSG00000248385
resolver
ensembl
ENSG00000273875
resolver
ensembl
ENSG00000274889
resolver
ensembl
ENSG00000275123
resolver
ensembl
ENSG00000275384
resolver
ensembl
ENSG00000275806
resolver
ensembl
ENSG00000276145
resolver
ensembl
ENSG00000276355
resolver
ensembl
ENSG00000276604
resolver
ensembl
ENSG00000277178
resolver
ensp
ENSP00000439454
resolver
ensp
ENSP00000477830
resolver
ensp
ENSP00000478234
resolver
ensp
ENSP00000478822
resolver
ensp
ENSP00000479062
resolver
ensp
ENSP00000479185
resolver
ensp
ENSP00000479374
resolver
ensp
ENSP00000479824
resolver
ensp
ENSP00000480049
resolver
ensp
ENSP00000480377
resolver
ensp
ENSP00000482624
resolver
ensp
ENSP00000484383
resolver
enst
ENST00000611088
resolver
enst
ENST00000611419
resolver
enst
ENST00000612678
resolver
enst
ENST00000614463
resolver
enst
ENST00000615726
resolver
enst
ENST00000616041
resolver
enst
ENST00000619320
resolver
enst
ENST00000620140
resolver
enst
ENST00000620398
resolver
enst
ENST00000620707
resolver
enst
ENST00000622245
resolver
genesymbol
TARM1
resolver
hgnc
HGNC:37250
resolver
uniprot
A0A087X1Q6
resolver
uniprot
B4DWY4
resolver
uniprot_entry
A0A087X1Q6_HUMAN
resolver
uniprot_entry
TARM1_HUMAN
resolver
uniprot_sec
B4DWY4
resolver
amino_acid_sequence
MIPKLLSLLCFRLCVGQGDTRGDGSLPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLDSTEGAAEFHLNNLKVRNAGEYTCEYYRKASPHILSQHSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRVTLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTKSPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRNVSPGESEAFKPE
uniprot
proteins
function
FUNCTION: May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901). Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity). {ECO:0000250|UniProtKB:B6A8R8, ECO:0000269|PubMed:26311901}.
uniprot
proteins
mass_dalton
29455
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:26311901}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
26311901
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26311901}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 237..257; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins