Nek4
entrez
23955
canonical
uniprot
Q9Z1J2
canonical
ensembl
ENSMUSG00000021918
resolver
ensp
ENSMUSP00000153710
resolver
ensp
ENSMUSP00000154090
resolver
ensp
ENSMUSP00000154678
resolver
enst
ENSMUST00000228328
resolver
genesymbol
Nek4
resolver
genesymbol_syn
Stk2
resolver
uniprot
A0A2I3BQ90
resolver
uniprot
O35673
resolver
uniprot
Q3UED6
resolver
uniprot
Q6GTE9
resolver
uniprot
Q9R1J1
resolver
uniprot_entry
A0A2I3BQ90_MOUSE
resolver
uniprot_entry
NEK4_MOUSE
resolver
uniprot_entry
Q3UED6_MOUSE
resolver
uniprot_entry
Q6GTE9_MOUSE
resolver
uniprot_sec
O35673
resolver
uniprot_sec
Q9R1J1
resolver
amino_acid_sequence
MPQAAYCYMRVVGRGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHGDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSILRQPYIKHHISLFLEATKAKTSKNNVKNCDSRAKPVAAVVSRKEESNTDVIHYQPRSSEGSALHVMGEDKCLSQEKPVDIGPLRSPASLEGHTGKQDMNNTGESCATISRINIDILPAERRDSANAGVVQESQPQHVDAADEVDSQCSISQEKERLQGNTKSSDQPGNLLPRRSSDGGDGEGSELVKPLYPSNKDQKPDQDQVTGIIENQDSIHPRSQPHSSMSEPSLSRQRRQKKREQTAHSGTKSQFQELPPRLLPSYPGIGKVDIIATQQNDGNQGGPVAGCVNSSRTSSTASAKDRPLSARERRRLKQSQEEMLPSGPAVQRTPSAVEPLKPQEEDQPIPAQRFSSDCSITQMNHTLPREKEKRLMHGLSEDELSSSTSSTDKSDGDSREGKSHTNEMKDLVQLMTQTLRLEAKESCEDLQVLNPGSEFRLHRKYRDTLVLHGKVAEEVEPHCTELPTGIIPGSEKIRRIVEVLRADVIQGLGIQLLEQVFDLLGEEDELEREARLQEHMGDKYTTYCVKARQLKFFEENVSF
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage (By similarity). Protein kinase that seems to act exclusively upon threonine residues. {ECO:0000250|UniProtKB:P51957, ECO:0000269|PubMed:10529384}.
uniprot
proteins
mass_dalton
88994
uniprot
proteins
protein_family
NEK Ser/Thr protein kinase family
uniprot
proteins
protein_family
NIMA subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
10393247
uniprot
proteins
pubmed
10529384
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
792
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10529384}. Cell projection, cilium {ECO:0000250|UniProtKB:P51957}.
uniprot
proteins