SERPINB5
entrez
5268
canonical
uniprot
P36952
canonical
ensembl
ENSG00000206075
resolver
ensp
ENSP00000372221
resolver
genesymbol
SERPINB5
resolver
genesymbol_syn
PI5
resolver
hgnc
HGNC:8949
resolver
uniprot
B2R6Y4
resolver
uniprot
Q6N0B4
resolver
uniprot
Q8WW89
resolver
uniprot_entry
SPB5_HUMAN
resolver
uniprot_sec
B2R6Y4
resolver
uniprot_sec
Q6N0B4
resolver
uniprot_sec
Q8WW89
resolver
amino_acid_sequence
MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP
uniprot
proteins
function
FUNCTION: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
uniprot
proteins
mass_dalton
42100
uniprot
proteins
protein_family
Ov-serpin subfamily
uniprot
proteins
protein_family
Serpin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15760906
uniprot
proteins
pubmed
16049006
uniprot
proteins
pubmed
16177791
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
7797587
uniprot
proteins
pubmed
8290962
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space.
uniprot
proteins