TRIM43
entrez
129868
canonical
uniprot
Q96BQ3
canonical
ensembl
ENSG00000144015
resolver
ensembl
ENSG00000292076
resolver
ensp
ENSP00000272395
resolver
ensp
ENSP00000517819
resolver
enst
ENST00000272395
resolver
enst
ENST00000709656
resolver
genesymbol
TRIM43
resolver
hgnc
HGNC:19015
resolver
uniprot
Q53TJ7
resolver
uniprot_entry
TRI43_HUMAN
resolver
uniprot_sec
Q53TJ7
resolver
amino_acid_sequence
MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPIEEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR
uniprot
proteins
function
FUNCTION: E3 ligase that regulates nuclear lamina integrity and the association of viral chromatin with transcriptionally-active host chromatin. Acts thereby as a herpesvirus-specific antiviral factor and mediates the ubiquitination-dependent proteasomal degradation of PCNT. {ECO:0000269|PubMed:30420784}.
uniprot
proteins
mass_dalton
52265
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
30420784
uniprot
proteins
sequence_length
446
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:30420784}.
uniprot
proteins