Stoml2
entrez
298203
canonical
uniprot
Q4FZT0
canonical
ensembl
ENSRNOG00000009535
resolver
ensembl
ENSRNOG00055016461
resolver
ensembl
ENSRNOG00060004429
resolver
ensembl
ENSRNOG00065004860
resolver
ensp
ENSRNOP00000013151
resolver
ensp
ENSRNOP00055022427
resolver
ensp
ENSRNOP00060005624
resolver
ensp
ENSRNOP00065004879
resolver
enst
ENSRNOT00000013151
resolver
enst
ENSRNOT00055027906
resolver
enst
ENSRNOT00060007424
resolver
enst
ENSRNOT00065007066
resolver
genesymbol
Stoml2
resolver
uniprot_entry
STML2_RAT
resolver
amino_acid_sequence
MLARAARGTGALLLRGSVQASGRIPRRASSGLPRNTVILFVPQQEAWVVERMGRFHRILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAPVPGAQNSSEARRDVQTTDTSIEELGRVKLS
uniprot
proteins
function
FUNCTION: Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
38414
uniprot
proteins
protein_family
Band 7/mec-2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
353
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9UJZ1}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UJZ1}. Mitochondrion {ECO:0000250|UniProtKB:Q9UJZ1}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9UJZ1}; Lipid-anchor {ECO:0000250|UniProtKB:Q9UJZ1}. Mitochondrion intermembrane space {ECO:0000250|UniProtKB:Q9UJZ1}. Membrane raft {ECO:0000250|UniProtKB:Q9UJZ1}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9UJZ1}. Note=Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain. Also associates with the actin cytoskeleton and membrane rafts in activated T-cells. A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells. {ECO:0000250|UniProtKB:Q9UJZ1}.
uniprot
proteins