Srsf6
entrez
67996
canonical
uniprot
Q3TWW8
canonical
ensembl
ENSMUSG00000016921
resolver
ensp
ENSMUSP00000119065
resolver
enst
ENSMUST00000130411
resolver
genesymbol
Srsf6
resolver
genesymbol_syn
Sfrs6
resolver
genesymbol_syn
Srp55
resolver
uniprot
Q3UJV5
resolver
uniprot
Q921K3
resolver
uniprot
Q9DBP1
resolver
uniprot_entry
SRSF6_MOUSE
resolver
uniprot_sec
Q3UJV5
resolver
uniprot_sec
Q921K3
resolver
uniprot_sec
Q9DBP1
resolver
amino_acid_sequence
MPRVYIGRLSYNVREKDIQRFFSGYGRLLEIDLKNGYGFVEFEDSRDADDAVYELNSKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDKYGKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSHSPLPAPPSKARSMSPPPKRASRSRSRSRSRSRSSSRD
uniprot
proteins
function
FUNCTION: Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
39025
uniprot
proteins
post_translational_modification
PTM: Extensively phosphorylated on serine residues in the RS domain. Phosphorylated by DYRK1A, probably in the RS domain. Phosphorylation by DYRK1A modulates alternative splice site selection and inhibits the expression of MAPT/Tau exon 10 (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Splicing factor SR family
uniprot
proteins
pubmed
10823932
uniprot
proteins
pubmed
12549914
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
339
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12549914}. Nucleus speckle {ECO:0000250|UniProtKB:Q13247}.
uniprot
proteins