Tubg1
entrez
252921
canonical
uniprot
P83888
canonical
ensembl
ENSRNOG00000020213
resolver
ensembl
ENSRNOG00055033520
resolver
ensembl
ENSRNOG00060013464
resolver
ensembl
ENSRNOG00065033318
resolver
ensp
ENSRNOP00000027370
resolver
ensp
ENSRNOP00055047768
resolver
ensp
ENSRNOP00060018168
resolver
ensp
ENSRNOP00065047103
resolver
enst
ENSRNOT00000027370
resolver
enst
ENSRNOT00055057928
resolver
enst
ENSRNOT00060022950
resolver
enst
ENSRNOT00065057262
resolver
genesymbol
Tubg1
resolver
genesymbol_syn
Tubg
resolver
uniprot
Q9Z310
resolver
uniprot_entry
TBG1_RAT
resolver
uniprot_sec
Q9Z310
resolver
amino_acid_sequence
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSSYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNLIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQFDKLRKREAFMEQFRKEDIFKDNFDEMDTSREIVQQLIDEYHAATRPDYISWGTQEQ
uniprot
proteins
function
FUNCTION: Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (By similarity). Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (By similarity). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (By similarity). Plays a role in sperm morphological development during late stage spermiogenesis, particularly the anchoring of the sperm head to the tail (By similarity). {ECO:0000250|UniProtKB:P23258, ECO:0000250|UniProtKB:P83887}.
uniprot
proteins
mass_dalton
51101
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome. {ECO:0000250}.
uniprot
proteins
protein_family
Tubulin family
uniprot
proteins
pubmed
10470852
uniprot
proteins
pubmed
15048127
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
451
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:P23258}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P23258}. Note=Localizes to mitotic spindle microtubules. {ECO:0000250|UniProtKB:P23258}.
uniprot
proteins