Btg2
entrez
29619
canonical
uniprot
P27049
canonical
ensembl
ENSRNOG00000003300
resolver
ensembl
ENSRNOG00055021880
resolver
ensembl
ENSRNOG00060017613
resolver
ensembl
ENSRNOG00065019487
resolver
ensp
ENSRNOP00000004408
resolver
ensp
ENSRNOP00055030613
resolver
ensp
ENSRNOP00060024290
resolver
ensp
ENSRNOP00065026249
resolver
enst
ENSRNOT00000004408
resolver
enst
ENSRNOT00055037530
resolver
enst
ENSRNOT00060030093
resolver
enst
ENSRNOT00065032838
resolver
genesymbol
Btg2
resolver
genesymbol_syn
Pc3
resolver
uniprot_entry
BTG2_RAT
resolver
amino_acid_sequence
MSHGKRTDMLPEIAAAVGFLTSLLRTRGCVSEQRLKVFSRALQDALTDHYKHHWFPEKPSKGSGYRCIRINHKMDPIISKVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSICVLYEEAPVATSYGLLTCKNQMMLGRSSPSKNYVMTVSS
uniprot
proteins
function
FUNCTION: Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
17728
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at Ser-147 by MAPK1/ERK2 and MAPK3/ERK1, and at Ser-149 by MAPK14, leading to PIN1-binding and mitochondrial depolarization. {ECO:0000250}.
uniprot
proteins
protein_family
BTG family
uniprot
proteins
pubmed
11237868
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1849653
uniprot
proteins
pubmed
7811636
uniprot
proteins
pubmed
8891336
uniprot
proteins
sequence_length
158
uniprot
proteins