Pin4
entrez
69713
canonical
uniprot
Q9CWW6
canonical
ensembl
ENSMUSG00000079480
resolver
ensp
ENSMUSP00000109257
resolver
enst
ENSMUST00000113627
resolver
genesymbol
Pin4
resolver
uniprot
Q0VE57
resolver
uniprot_entry
PIN4_MOUSE
resolver
uniprot_sec
Q0VE57
resolver
amino_acid_sequence
MPPKGKSGSGKGGKGGAASGSDSADKKSQGPKGGGNAVKVRHILCEKHGKIMEAMEKLKSGMRFSEVATQYSEDKARQGGDLGWMTRGSMVGPFQEAAFALPVSGMDKPVFTDPPVKTKFGYHIIMVEGRK
uniprot
proteins
ec_number
5.2.1.8
uniprot
proteins
function
FUNCTION: Involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double-stranded DNA (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
13815
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. Phosphorylation occurs both in the nucleus and the cytoplasm. Phosphorylation at Ser-19 does not affect its PPIase activity but is required for nuclear localization, and the dephosphorylation is a prerequisite for the binding to DNA. The unphosphorylated form associates with the pre-rRNP complexes in the nucleus (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
PIN4 subfamily
uniprot
proteins
protein_family
PpiC/parvulin rotamase family
uniprot
proteins
pubmed
11960984
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
131
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Colocalizes in the nucleolus during interphase and on the spindle apparatus during mitosis with NPM1. {ECO:0000250}.
uniprot
proteins