TEX101
entrez
83639
canonical
uniprot
Q9BY14
canonical
ensembl
ENSG00000131126
resolver
ensp
ENSP00000472308
resolver
ensp
ENSP00000472769
resolver
genesymbol
TEX101
resolver
genesymbol_syn
SGRG
resolver
hgnc
HGNC:30722
resolver
uniprot
Q7L5R2
resolver
uniprot
Q9BPY7
resolver
uniprot_entry
TX101_HUMAN
resolver
uniprot_sec
Q7L5R2
resolver
uniprot_sec
Q9BPY7
resolver
amino_acid_sequence
MGTPRIQHLLILLVLGASLLTSGLELYCQKGLSMTVEADPANMFNWTTEEVETCDKGALCQETILIIKAGTETAILATKGCIPEGEEAITIVQHSSPPGLIVTSYSNYCEDSFCNDKDSLSQFWEFSETTASTVSTTLHCPTCVALGTCFSAPSLPCPNGTTRCYQGKLEITGGGIESSVEVKGCTAMIGCRLMSGILAVGPMFVREACPHQLLTQPRKTENGATCLPIPVWGLQLLLPLLLPSFIHFS
uniprot
proteins
function
FUNCTION: Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity). {ECO:0000250|UniProtKB:Q924B5, ECO:0000250|UniProtKB:Q9JMI7}.
uniprot
proteins
mass_dalton
26667
uniprot
proteins
post_translational_modification
PTM: N-glycosylated; by high mannose and/or biantennary complex and/or certain types of hybrid oligosaccharides; possesses different oligosaccharides chains according to its subcellular localization in the testis. {ECO:0000250|UniProtKB:Q9JMI7}.; PTM: Sheds from membrane raft by ACE and released from the cell surface of epididymal sperm while it passes through the caput epididymis leading to disappearance of TEX101 on spermatozoa; is essential to produce fertile spermatozoa. {ECO:0000250|UniProtKB:Q9JMI7}.
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16516155
uniprot
proteins
sequence_length
249
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9JMI7}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9JMI7}. Membrane raft {ECO:0000250|UniProtKB:Q9JMI7}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9JMI7}. Secreted {ECO:0000250|UniProtKB:Q9JMI7}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q9JMI7}. Note=Located on plasma membrane of spermatocytes, round and elongated spermatids, and testicular spermatozoa. {ECO:0000250|UniProtKB:Q9JMI7}.
uniprot
proteins