Ren2
entrez
19702
canonical
uniprot
P00796
canonical
genesymbol
Ren2
resolver
genesymbol_syn
Ren-2
resolver
uniprot
P70229
resolver
uniprot
P97955
resolver
uniprot
Q62155
resolver
uniprot_entry
RENI2_MOUSE
resolver
uniprot_sec
P70229
resolver
uniprot_sec
P97955
resolver
uniprot_sec
Q62155
resolver
amino_acid_sequence
MDRRRMPLWALLLLWSPCTFSLPTGTTFERIPLKKMPSVREILEERGVDMTRLSAEWDVFTKRSSLTDLISPVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAQFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHLLGGEVVLGGSDPEHYQGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
uniprot
proteins
ec_number
3.4.23.15
uniprot
proteins
function
FUNCTION: Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. {ECO:0000250|UniProtKB:P00797}.
uniprot
proteins
mass_dalton
44283
uniprot
proteins
protein_family
Peptidase A1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1608447
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2691339
uniprot
proteins
pubmed
6089205
uniprot
proteins
pubmed
6283373
uniprot
proteins
pubmed
6357783
uniprot
proteins
pubmed
6392850
uniprot
proteins
pubmed
6812055
uniprot
proteins
sequence_length
401
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P00797}.
uniprot
proteins