Sdhaf3
entrez
71238
canonical
uniprot
Q8BQU3
canonical
ensembl
ENSMUSG00000042505
resolver
ensp
ENSMUSP00000040935
resolver
ensp
ENSMUSP00000289794
resolver
ensp
ENSMUSP00000289796
resolver
enst
ENSMUST00000040826
resolver
genesymbol
Sdhaf3
resolver
genesymbol_syn
Acn9
resolver
uniprot
Q0VF92
resolver
uniprot
Q8BT21
resolver
uniprot_entry
Q0VF92_MOUSE
resolver
uniprot_entry
SDHF3_MOUSE
resolver
uniprot_sec
Q8BT21
resolver
amino_acid_sequence
MPGKHVSRVRALYRRILLLHRALPPDLKALGDQYVKDEFRRHKTVGPGEAQRFLKEWETYAAVLWQQAEDSRQSSTGKACFGTSLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSITESTKPQL
uniprot
proteins
function
FUNCTION: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit Sdhb of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. {ECO:0000250|UniProtKB:Q04401, ECO:0000250|UniProtKB:Q8SZ16}.
uniprot
proteins
mass_dalton
14468
uniprot
proteins
protein_family
Complex I LYR family
uniprot
proteins
protein_family
SDHAF3 subfamily
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
125
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q04401}.
uniprot
proteins