Ahcyl2
entrez
74340
canonical
uniprot
Q68FL4
canonical
ensembl
ENSMUSG00000029772
resolver
ensp
ENSMUSP00000067638
resolver
ensp
ENSMUSP00000100060
resolver
ensp
ENSMUSP00000110893
resolver
ensp
ENSMUSP00000110897
resolver
ensp
ENSMUSP00000135518
resolver
enst
ENSMUST00000064872
resolver
enst
ENSMUST00000102995
resolver
enst
ENSMUST00000125911
resolver
genesymbol
Ahcyl2
resolver
uniprot
A0A1Y1B7R3
resolver
uniprot
F8WGT1
resolver
uniprot
F8WI65
resolver
uniprot
H3BKT5
resolver
uniprot
Q8BIH1
resolver
uniprot_entry
A0A1Y1B7R3_MOUSE
resolver
uniprot_entry
F8WGT1_MOUSE
resolver
uniprot_entry
F8WI65_MOUSE
resolver
uniprot_entry
H3BKT5_MOUSE
resolver
uniprot_entry
SAHH3_MOUSE
resolver
uniprot_sec
Q8BIH1
resolver
amino_acid_sequence
MSVQVVSAAAAAKVPEVELKDLSPSEAEPQLGLSAAAVGAMVPPAGGGDPEAPAPAPAAERPPAPGPGSGPTAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKQIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
uniprot
proteins
function
FUNCTION: Regulatory protein that interacts with and modulates the activity of membrane ion transporters, including the sodium-bicarbonate cotransporter SLC4A4, through phosphorylation-dependent binding. Functions as a homolog of AHCYL1 to regulate bicarbonate transport and intracellular pH homeostasis via direct interactions rather than enzymatic activity (PubMed:27382360). On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1,4,5-trisphosphate (By similarity). {ECO:0000250|UniProtKB:A6QLP2, ECO:0000269|PubMed:27382360}.
uniprot
proteins
mass_dalton
66899
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during neuronal differentiation at the LISN domain. {ECO:0000269|PubMed:19220705}.
uniprot
proteins
protein_family
Adenosylhomocysteinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17114649
uniprot
proteins
pubmed
19220705
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27382360
uniprot
proteins
sequence_length
613
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:A6QLP2, ECO:0000269|PubMed:19220705}. Microsome {ECO:0000269|PubMed:19220705}. Note=Associates with membranes when phosphorylated, probably through interaction with ITPR1. {ECO:0000269|PubMed:19220705}.
uniprot
proteins