Slc6a17
entrez
613226
canonical
uniprot
P31662
canonical
ensembl
ENSRNOG00000050090
resolver
ensembl
ENSRNOG00055020383
resolver
ensembl
ENSRNOG00060024513
resolver
ensembl
ENSRNOG00065023082
resolver
ensp
ENSRNOP00000065179
resolver
ensp
ENSRNOP00055028241
resolver
ensp
ENSRNOP00060035162
resolver
ensp
ENSRNOP00065032084
resolver
enst
ENSRNOT00000075653
resolver
enst
ENSRNOT00055034824
resolver
enst
ENSRNOT00060042446
resolver
enst
ENSRNOT00065039458
resolver
genesymbol
Slc6a17
resolver
genesymbol_syn
Ntt4
resolver
genesymbol_syn
Rxt1
resolver
uniprot_entry
S6A17_RAT
resolver
amino_acid_sequence
MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGETGGKQKVAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYNVIMTVKEKQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLESSSHPNGRYGSGYLLASTPESEL
uniprot
proteins
function
FUNCTION: Synaptic vesicle transporter with apparent selectivity for neutral amino acids. The transport is sodium-coupled but chloride-independent, likely driven by the proton electrochemical gradient generated by vacuolar H(+)-ATPase in an overall electrogenic mechanism. May contribute to the synaptic uptake of neurotransmitter precursors in a process coupled in part to vesicle exocytosis. {ECO:0000269|PubMed:18768736, ECO:0000269|PubMed:19147495}.
uniprot
proteins
mass_dalton
81055
uniprot
proteins
protein_family
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family
uniprot
proteins
pubmed
16125675
uniprot
proteins
pubmed
18768736
uniprot
proteins
pubmed
19147495
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8093354
uniprot
proteins
pubmed
8294906
uniprot
proteins
sequence_length
727
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:18768736, ECO:0000269|PubMed:19147495}; Multi-pass membrane protein {ECO:0000269|PubMed:18768736, ECO:0000269|PubMed:19147495}. Postsynapse {ECO:0000250|UniProtKB:Q8BJI1}. Presynapse {ECO:0000250|UniProtKB:Q8BJI1}. Note=Localizes at synaptic junctions - at both pre- and post-synaptic sites - particularly in excitatory glutamatergic terminals. {ECO:0000250|UniProtKB:Q8BJI1}.
uniprot
proteins
transmembrane_region
TRANSMEM 69..89; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 97..116; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 225..243; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 252..269; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 305..322; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 334..355; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 452..471; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 495..513; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 529..549; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 570..591; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 619..641; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins