Far2
entrez
330450
canonical
uniprot
Q7TNT2
canonical
ensembl
ENSMUSG00000030303
resolver
ensp
ENSMUSP00000032443
resolver
ensp
ENSMUSP00000107234
resolver
ensp
ENSMUSP00000296736
resolver
genesymbol
Far2
resolver
uniprot
B2KFC6
resolver
uniprot
Q3TTT7
resolver
uniprot
Q8BH72
resolver
uniprot
Q8CAK7
resolver
uniprot_entry
FACR2_MOUSE
resolver
uniprot_sec
B2KFC6
resolver
uniprot_sec
Q3TTT7
resolver
uniprot_sec
Q8BH72
resolver
uniprot_sec
Q8CAK7
resolver
amino_acid_sequence
MSMIAAFYSNKSILITGATGFLGKVLMEKLFRTSPHLKVIYILVRPKSGQTLQERVFQILNSKLFEKVKEVCPNVHEKIRPISADLNQRDFAISKEDVQELLSCTNIIFHCAATVRFDAHLREAVQLNVTATQQLLLMASQMPKLEAFIHISTAFSNCNLSHIDEVIYPCPVEPRKIIDSMEWLDDSIIEEITPKLIGDRPNTYTYTKALGEIVVQQESGNLNVAIVRPSIVGATWQEPFPGWVDNLNGPSGLIIATGKGFLRSIKATPMAVADVIPVDTVVNLTIAVGWYTAVHRPKSTLIYHSTSGNLNPCNWYKMGLQVLATIEKIPFESAFRRPNADFTTSNFTTHYWNTVSHRVPAIIYDFYLRLTGRKPRMLKLMNRLLKTISMLEYFINHSWEWSTNNTEMLLSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLKEDLAGIPKAKQHLRRLRNIHYLFNTALFLIIWRLLIARSQMARNVWFFIVSFCYKFISYFRASSTLKV
uniprot
proteins
ec_number
1.2.1.84
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols (PubMed:15220348). A lower activity can be observed with shorter fatty acyl-CoA substrates (PubMed:15220348). Can produce very long-chain and ultra long-chain FAls, regardless of whether they have a straight or branched chain (PubMed:35238077). It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates (PubMed:35238077). {ECO:0000269|PubMed:15220348, ECO:0000269|PubMed:35238077}.
uniprot
proteins
mass_dalton
59167
uniprot
proteins
protein_family
Fatty acyl-CoA reductase family
uniprot
proteins
pubmed
15220348
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
35238077
uniprot
proteins
sequence_length
515
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000269|PubMed:15220348}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q96K12}.
uniprot
proteins
transmembrane_region
TRANSMEM 465..484; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins