Gpr176
entrez
381413
canonical
uniprot
Q80WT4
canonical
ensembl
ENSMUSG00000040133
resolver
ensp
ENSMUSP00000037586
resolver
enst
ENSMUST00000039160
resolver
genesymbol
Gpr176
resolver
genesymbol_syn
Agr9
resolver
genesymbol_syn
Gm1012
resolver
uniprot
Q80UC4
resolver
uniprot_entry
GP176_MOUSE
resolver
uniprot_sec
Q80UC4
resolver
amino_acid_sequence
MGHNSSWVSPNTSHPRNTSGAEAGANLSAFGELSEAQLYRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASVVCVPFDIILSSSPHCCWWIYTMLFCKVLKFLHKVFCSVTVLSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAVTNVADIYAMSTCTEVWSNSLGHLVYVLIYNVTTVIVPVAVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVTVFILCSVPYATLVVYQTVLNVPNTSVFLLLTAIWLPKVSLLANPVLFLTVNKSVRKCLVGTLVQLHHRYSRRNVVSTGSGVAEPSLEPSMRSGSQLLEMFHIGQQQIFKPSEDEEESEAKYLGSADFQAKEVLTSCPEGEQEPPQLAPSVPPPGTVDSEPRVSPVAPMESGIFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLGNTPEELIQTKVPRVNRVERKMSRNNKVSIFPKVDS
uniprot
proteins
function
FUNCTION: Orphan receptor involved in normal circadian rhythm behavior (PubMed:26882873). Acts through the G protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production (PubMed:26882873). {ECO:0000269|PubMed:26882873}.
uniprot
proteins
mass_dalton
57143
uniprot
proteins
mutagenesis
MUTAGEN 140..141; /note="DR->RD: Decreases expression; No reduction of cAMP upon induction."; /evidence="ECO:0000269|PubMed:26882873"; MUTAGEN 145; /note="V->R: No reduction of cAMP upon induction."; /evidence="ECO:0000269|PubMed:26882873
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12679517
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
26882873
uniprot
proteins
sequence_length
515
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:26882873}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 42..64; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 78..98; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 109..129; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 158..177; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 205..225; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 265..285; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 302..322; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins