Cd300ld
entrez
217305
canonical
uniprot
Q8VCH2
canonical
ensembl
ENSMUSG00000034641
resolver
ensp
ENSMUSP00000047022
resolver
enst
ENSMUST00000045075
resolver
genesymbol
Cd300ld
resolver
genesymbol_syn
Clm5
resolver
genesymbol_syn
Lmir4
resolver
uniprot
Q8BRU3
resolver
uniprot_entry
CLM5_MOUSE
resolver
uniprot_sec
Q8BRU3
resolver
amino_acid_sequence
MWQFSALLLFFLPGCCTAQDSVTGPEEVSGQEQGSLTVQCRYSSYWKGYKKYWCRGVPQRSCDILVETDKSEQLVKKNRVSIRDNQRDFIFTVTMEDLRMSDAGIYWCGITKGGPDPMFKVNVNIDQAPKSSMMTTTATVLKSIQPSAENTGKEQVTQSKEVTQSRPHTRSLLSSIYFLLMVFVELPLLLSMLSAVLWVTRPQRCFGRGENDLVKTHSPVA
uniprot
proteins
function
FUNCTION: Acts as an activating receptor in myeloid cells and mast cells. {ECO:0000269|PubMed:16940041, ECO:0000269|PubMed:17438331}.; FUNCTION: (Microbial infection) Acts as a functional murine norovirus (MNV) receptor. Primary determinant of MNV species tropism and is sufficient to render cells permissive to infection by MNV. Can render nonmurine mammalian cells susceptible to MNV infection (PubMed:27540007, PubMed:27681626). {ECO:0000269|PubMed:27540007, ECO:0000269|PubMed:27681626}.
uniprot
proteins
mass_dalton
24954
uniprot
proteins
mutagenesis
MUTAGEN 165..170; /note="SRPHTR->NSLFIW: Decreases surface expression in transfected pro-B cells and impairs interaction with FCER1G."; /evidence="ECO:0000269|PubMed:20817736"; MUTAGEN 177..186; /note="YFLLMVFVEL->SFLLMVFVVV: Increases surface expression in transfected pro-B cells and impairs interaction with FCER1G."; /evidence="ECO:0000269|PubMed:20817736
uniprot
proteins
post_translational_modification
PTM: O-glycosylated. {ECO:0000269|PubMed:17438331}.
uniprot
proteins
protein_family
CD300 family
uniprot
proteins
pubmed
14662855
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16940041
uniprot
proteins
pubmed
17438331
uniprot
proteins
pubmed
20817736
uniprot
proteins
pubmed
27540007
uniprot
proteins
pubmed
27681626
uniprot
proteins
sequence_length
221
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16940041}; Single-pass type I membrane protein {ECO:0000269|PubMed:16940041}.
uniprot
proteins
transmembrane_region
TRANSMEM 178..198; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins