Hnrnpdl
entrez
305178
canonical
uniprot
Q3SWU3
canonical
ensembl
ENSRNOG00000002270
resolver
ensp
ENSRNOP00000003106
resolver
ensp
ENSRNOP00000075589
resolver
enst
ENSRNOT00000003106
resolver
enst
ENSRNOT00000079767
resolver
genesymbol
Hnrnpdl
resolver
genesymbol_syn
Hnrpdl
resolver
uniprot
A0A0G2KAZ7
resolver
uniprot_entry
A0A0G2KAZ7_RAT
resolver
uniprot_entry
HNRDL_RAT
resolver
amino_acid_sequence
MTGTARSALPLPQSPARALRPSGAARAAPSLSPSRFSACPLDPSSFPTSGNKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGDESYSGYGGYDYTGYNYGSYGYGQGYTDYSGQQSTYGKASRGGGNHQNNYQPY
uniprot
proteins
function
FUNCTION: Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
35294
uniprot
proteins
post_translational_modification
PTM: Dimethylation of Arg-310 is probably of the asymmetric type. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
322
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O14979}. Cytoplasm {ECO:0000250|UniProtKB:O14979}. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner. {ECO:0000250|UniProtKB:O14979}.
uniprot
proteins