Crat
entrez
311849
canonical
uniprot
Q704S8
canonical
ensembl
ENSRNOG00000018145
resolver
ensembl
ENSRNOG00055007104
resolver
ensembl
ENSRNOG00060031299
resolver
ensembl
ENSRNOG00065020702
resolver
ensp
ENSRNOP00000063089
resolver
ensp
ENSRNOP00055009311
resolver
ensp
ENSRNOP00060045030
resolver
ensp
ENSRNOP00065028230
resolver
enst
ENSRNOT00000065128
resolver
enst
ENSRNOT00055011782
resolver
enst
ENSRNOT00060054358
resolver
enst
ENSRNOT00065035111
resolver
genesymbol
Crat
resolver
uniprot_entry
CACP_RAT
resolver
amino_acid_sequence
MLAFAARTVVKPLGLLKPSSLMKVSGRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVLLPKQDFMDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGLKQDSVVNFLKSKKPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNSWAKAYSSLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRSHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNISIMIQDLDIMMLVFHHFGKDFPKSQKLSPDAFIQIALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASTDSLAFVKGMDDPKVPEQQRVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMSFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAKL
uniprot
proteins
ec_number
2.3.1.137
uniprot
proteins
ec_number
2.3.1.7
uniprot
proteins
function
FUNCTION: Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates. {ECO:0000250|UniProtKB:P43155}.
uniprot
proteins
mass_dalton
70801
uniprot
proteins
mutagenesis
MUTAGEN 343; /note="H->A: Loss of enzyme activity."; /evidence="ECO:0000269|PubMed:15155769"; MUTAGEN 347; /note="E->A: Loss of enzyme activity."; /evidence="ECO:0000269|PubMed:15155769"; MUTAGEN 564; /note="M->A: Increases activity towards medium chain fatty acids."; /evidence="ECO:0000269|PubMed:15155769"; MUTAGEN 564; /note="M->G: Increases activity towards medium and long chain fatty acids."; /evidence="ECO:0000269|PubMed:15155769
uniprot
proteins
protein_family
Carnitine/choline acetyltransferase family
uniprot
proteins
pubmed
15155769
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19423663
uniprot
proteins
sequence_length
626
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000305}. Peroxisome {ECO:0000305}. Mitochondrion inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
uniprot
proteins