GAL3ST4
entrez
79690
canonical
uniprot
Q96RP7
canonical
ensembl
ENSG00000197093
resolver
ensp
ENSP00000353142
resolver
genesymbol
GAL3ST4
resolver
hgnc
HGNC:24145
resolver
uniprot
A4D2A8
resolver
uniprot
B4DWL8
resolver
uniprot
D6W5U5
resolver
uniprot
Q8N3P7
resolver
uniprot
Q8WZ17
resolver
uniprot
Q96E33
resolver
uniprot
Q9HA78
resolver
uniprot_entry
G3ST4_HUMAN
resolver
uniprot_sec
A4D2A8
resolver
uniprot_sec
B4DWL8
resolver
uniprot_sec
D6W5U5
resolver
uniprot_sec
Q8N3P7
resolver
uniprot_sec
Q8WZ17
resolver
uniprot_sec
Q96E33
resolver
uniprot_sec
Q9HA78
resolver
activity_regulation
ACTIVITY REGULATION: Inhibition by Mn(2+) at high Mn(2+) concentrations. {ECO:0000269|PubMed:14701868}.
uniprot
proteins
amino_acid_sequence
MGPLSPARTLRLWGPRSLGVALGVFMTIGFALQLLGGPFQRRLPGLQLRQPSAPSLRPALPSCPPRQRLVFLKTHKSGSSSVLSLLHRYGDQHGLRFALPARYQFGYPKLFQASRVKGYRPQGGGTQLPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALARSAFSYYKSTSSAFRKSPSLAAFLANPRGFYRPGARGDHYARNLLWFDFGLPFPPEKRAKRGNIHPPRDPNPPQLQVLPSGAGPRAQTLNPNALIHPVSTVTDHRSQISSPASFDLGSSSFIQWGLAWLDSVFDLVMVAEYFDESLVLLADALCWGLDDVVGFMHNAQAGHKQGLSTVSNSGLTAEDRQLTARARAWNNLDWALYVHFNRSLWARIEKYGQGRLQTAVAELRARREALAKHCLVGGEASDPKYITDRRFRPFQFGSAKVLGYILRSGLSPQDQEECERLATPELQYKDKLDAKQFPPTVSLPLKTSRPLSP
uniprot
proteins
ec_number
2.8.2.-
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of a sulfate group from 3'-phosphoadenylyl sulfate (PAPS) to the C-3 hydroxyl group of terminal non-reducing beta-1,3-linked galactose residues, exclusively in O-linked glycoproteins (PubMed:11333265, PubMed:14701868). Participates in galactose sulfation and acts on core 1 (Gal-beta-1,3-GalNAc-R) structures (PubMed:11333265, PubMed:14701868). In vitro, also recognizes Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc-R, asialofetuin, the Globo H precursor and Gal-beta-1,3(6-O-sulfo)GalNAc-R structures as good substrates (PubMed:11333265, PubMed:14701868). {ECO:0000269|PubMed:11333265, ECO:0000269|PubMed:14701868}.
uniprot
proteins
mass_dalton
54166
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; carbohydrate sulfation. {ECO:0000269|PubMed:11333265, ECO:0000269|PubMed:14701868}.
uniprot
proteins
protein_family
Galactose-3-O-sulfotransferase family
uniprot
proteins
pubmed
11333265
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14701868
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15498874
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
486
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins