Inpp5a
entrez
212111
canonical
uniprot
Q7TNC9
canonical
ensembl
ENSMUSG00000025477
resolver
ensp
ENSMUSP00000026550
resolver
ensp
ENSMUSP00000095589
resolver
ensp
ENSMUSP00000101704
resolver
enst
ENSMUST00000097975
resolver
genesymbol
Inpp5a
resolver
uniprot
E9QAS7
resolver
uniprot
F6XAA4
resolver
uniprot
Q3TZT4
resolver
uniprot
Q8BNK3
resolver
uniprot_entry
F6XAA4_MOUSE
resolver
uniprot_entry
I5P1_MOUSE
resolver
uniprot_entry
Q3TZT4_MOUSE
resolver
uniprot_sec
E9QAS7
resolver
uniprot_sec
Q8BNK3
resolver
amino_acid_sequence
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVLHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYKKVTGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGVRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVVLQLEKKLFDYFNQDVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDSSQGEQYMNTRCPAWCDRILMSLSAKELVLKSESEEKVATYDHIGPNVCMGDHKPVFLAFRIAPGAGKPHAHVHKCCVVQ
uniprot
proteins
ec_number
3.1.3.56
uniprot
proteins
function
FUNCTION: Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate (PubMed:26051944). Plays a crucial role in the survival of cerebellar Purkinje cells (PubMed:26051944). {ECO:0000269|PubMed:26051944}.
uniprot
proteins
mass_dalton
47622
uniprot
proteins
post_translational_modification
PTM: Isoprenylation at Cys-409 is required for localization at the membrane. {ECO:0000250|UniProtKB:Q14642}.
uniprot
proteins
protein_family
4
uniprot
proteins
protein_family
5-trisphosphate 5-phosphatase type I family
uniprot
proteins
protein_family
Inositol 1
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26051944
uniprot
proteins
pubmed
31112734
uniprot
proteins
pubmed
34272044
uniprot
proteins
sequence_length
412
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q14642}; Lipid-anchor {ECO:0000250|UniProtKB:Q14642}. Cell projection, dendrite {ECO:0000269|PubMed:26051944}.
uniprot
proteins