Irf2bpl
entrez
314329
canonical
uniprot
Q5EIC4
canonical
ensembl
ENSRNOG00000011026
resolver
ensembl
ENSRNOG00055027463
resolver
ensembl
ENSRNOG00060025559
resolver
ensembl
ENSRNOG00065028058
resolver
ensp
ENSRNOP00000064525
resolver
ensp
ENSRNOP00055039120
resolver
ensp
ENSRNOP00060036677
resolver
ensp
ENSRNOP00065039668
resolver
enst
ENSRNOT00000014645
resolver
enst
ENSRNOT00055047543
resolver
enst
ENSRNOT00060044230
resolver
enst
ENSRNOT00065048347
resolver
genesymbol
Irf2bpl
resolver
genesymbol_syn
Eap1
resolver
genesymbol_syn
Pqcp
resolver
uniprot
M0R567
resolver
uniprot
Q4G048
resolver
uniprot_entry
I2BPL_RAT
resolver
uniprot_entry
M0R567_RAT
resolver
uniprot_sec
Q4G048
resolver
amino_acid_sequence
MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAQQQQQQQQQQQQQQQQQPQQLNHVDGSTKPAVLPAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHAARLPNGLGGPNGFPKPAPEEGPPELNRQSPNSSSAATSVASRRGTHSGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPHGLGGSRGPPTPAPPGAPGGPACLGGPPGVSATVSSAPSSTSSTVAEVGVGAAGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWANKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPTGRGAAASLRKRKASPEPPDSAESALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway. Probably plays a role in the development of the central nervous system and in neuronal maintenance (By similarity). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter. {ECO:0000250|UniProtKB:Q9H1B7, ECO:0000269|PubMed:17627301}.
uniprot
proteins
mass_dalton
81496
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:Q9H1B7}.
uniprot
proteins
protein_family
IRF2BP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17627301
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
783
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17627301}.
uniprot
proteins