Pofut4
entrez
286971
canonical
uniprot
Q68FV3
canonical
ensembl
ENSRNOG00000009274
resolver
ensembl
ENSRNOG00055019429
resolver
ensembl
ENSRNOG00060012622
resolver
ensembl
ENSRNOG00065010402
resolver
ensp
ENSRNOP00000012300
resolver
ensp
ENSRNOP00055026884
resolver
ensp
ENSRNOP00060016931
resolver
ensp
ENSRNOP00065012873
resolver
enst
ENSRNOT00000012300
resolver
enst
ENSRNOT00055033167
resolver
enst
ENSRNOT00060021432
resolver
enst
ENSRNOT00065016832
resolver
genesymbol
Pofut4
resolver
genesymbol_syn
Fut11
resolver
uniprot
Q8CG40
resolver
uniprot_entry
OFUT4_RAT
resolver
uniprot_sec
Q8CG40
resolver
amino_acid_sequence
MAARYTEAVLAALGVLSVCSASSSSGSGASGKAGGEAEWAEPWDGAVFRPPAALGAVGMTRGLGSPPPGNAETVDLPVLLWWSPGLFPHFPGDSERIECALGACVASRDRRARADPRTRALLFYGTDFRAADAPLPRLAHQSWALLHEESPLNNFLLSHGPGIRLFNLTATFSRHSDYPLPLQWLPGAAYLRRPAPPLRERAEWRRRGYAPLLYLQSHCDVPSDRDRYVRELMRYIPVDSYGKCLQNREPPTVRLQDTATATTEDPELMAFLSRYKFHLAMENAICNDYMTEKLWRPMHLGAVPVYRGSPSVRDWMPNNHSVILIDDFESPQKLAEFIDFLDKNDEEYMKYLAYKQPGGITNQFLLDNLEHREWGVNDPMLPNYLNGFECFVCDHELARLDAEKAHESSPRDIPVLEPHIAQLSHMDCPVPTPGFGKVEEIPENDSWKEMWLQDYWQGLYQGEALTAMIHNNETQQSKFWDYVHEIFMKRNKNL
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
ec_number
2.4.1.221
uniprot
proteins
function
FUNCTION: Protein O-fucosyltransferase that specifically catalyzes O-fucosylation of serine or threonine residues in EMI domains of target proteins, such as MMRN1, MMRN2 and EMID1. Attaches fucose through an O-glycosidic linkage. O-fucosylation of EMI domain-containing proteins may be required for facilitating protein folding and secretion. Also shows minor alpha-(1,3)-fucosyltransferase activity toward activity toward biantennary N-glycan acceptors. However, this was tested with a library of synthetic substrates and this activity is unsure in vivo. {ECO:0000250|UniProtKB:Q495W5}.
uniprot
proteins
mass_dalton
56000
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q495W5}.
uniprot
proteins
protein_family
Glycosyltransferase 10 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
494
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q495W5}; Single-pass type II membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..24; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins