FCGR2C
entrez
9103
canonical
uniprot
P31995
canonical
genesymbol
FCGR2C
resolver
genesymbol_syn
CD32
resolver
genesymbol_syn
FCG2
resolver
genesymbol_syn
IGFR2
resolver
hgnc
HGNC:15626
resolver
uniprot
O00523
resolver
uniprot
O00524
resolver
uniprot
O00525
resolver
uniprot_entry
FCG2C_HUMAN
resolver
uniprot_sec
O00523
resolver
uniprot_sec
O00524
resolver
uniprot_sec
O00525
resolver
amino_acid_sequence
MGILSFLPVLATESDWADCKSPQPWGHMLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQPEETNNDYETADGGYMTLNPRAPTDDDKNIYLTLPPNDHVNSNN
uniprot
proteins
function
FUNCTION: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.
uniprot
proteins
mass_dalton
35578
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN and SYK. {ECO:0000269|PubMed:8756631}.
uniprot
proteins
pubmed
23744091
uniprot
proteins
pubmed
2531080
uniprot
proteins
pubmed
8756631
uniprot
proteins
pubmed
9516136
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform IIC4]: Cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform IIC3]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform IIC2]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform IIC1]: Cell membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 224..246; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins