MFSD6
entrez
54842
canonical
uniprot
Q6ZSS7
canonical
ensembl
ENSG00000151690
resolver
ensp
ENSP00000281416
resolver
ensp
ENSP00000376141
resolver
ensp
ENSP00000406837
resolver
ensp
ENSP00000531485
resolver
ensp
ENSP00000531486
resolver
ensp
ENSP00000531487
resolver
ensp
ENSP00000531488
resolver
ensp
ENSP00000531489
resolver
ensp
ENSP00000632493
resolver
ensp
ENSP00000632494
resolver
enst
ENST00000281416
resolver
enst
ENST00000392328
resolver
enst
ENST00000861426
resolver
enst
ENST00000861427
resolver
enst
ENST00000861428
resolver
enst
ENST00000861429
resolver
enst
ENST00000861430
resolver
enst
ENST00000962434
resolver
enst
ENST00000962435
resolver
genesymbol
MFSD6
resolver
genesymbol_syn
MMR2
resolver
hgnc
HGNC:24711
resolver
uniprot
B7Z7Y2
resolver
uniprot
D3KSZ4
resolver
uniprot
Q86TH2
resolver
uniprot
Q9NXM3
resolver
uniprot_entry
B7Z7Y2_HUMAN
resolver
uniprot_entry
MFSD6_HUMAN
resolver
uniprot_sec
D3KSZ4
resolver
uniprot_sec
Q86TH2
resolver
uniprot_sec
Q9NXM3
resolver
amino_acid_sequence
MADDKVAILTDDEEEQKRKYVLADPFNGISREPEPPSNETPSSTETSAIPEEEIDWIEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVKPATLRCVPKIRPTTHPTNASHQLTILPTNSSFTSFLTISPKMREKRNLLETRLNVSDTVTLPTAPNMNSEPTLQPQTGEITNRMMDLTLNSSTATPVSPGSVTKETTTVIVTTTKSLPSDQVMLVYDQQEVEAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIEVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFKNDDSKGKEVEIPQVERNNSTESSEETPTTTSHSQAFNFWDLIKLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPRIEPRLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFVYALYQIKEMMQLTRDNRASEIQPLQGTNENRENSPAGRAQPVPCETHSDPSRNQPSPDAAASQTQTSPAHPSVDPCTEESEEQQAQLAAGGH
uniprot
proteins
function
FUNCTION: (Microbial infection) Acts as a receptor for respiratory enterovirus D68 (PubMed:39798568, PubMed:40132641). Mechanistically, binds to viral particles and is required for viral cell entry while initial attachment to cells is mainly mediated by interactions with sialic acid (PubMed:40132641). {ECO:0000269|PubMed:39798568, ECO:0000269|PubMed:40132641}.
uniprot
proteins
mass_dalton
88088
uniprot
proteins
protein_family
MFSD6 family
uniprot
proteins
protein_family
Major facilitator superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20123006
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
39798568
uniprot
proteins
pubmed
40132641
uniprot
proteins
sequence_length
791
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:39798568}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 105..125; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 132..152; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 286..306; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 335..355; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 369..389; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 450..470; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 479..499; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 507..527; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 544..564; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 579..599; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 605..625; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins