ING5
entrez
84289
canonical
uniprot
Q8WYH8
canonical
ensembl
ENSG00000168395
resolver
ensp
ENSP00000322142
resolver
ensp
ENSP00000385937
resolver
ensp
ENSP00000490767
resolver
ensp
ENSP00000755269
resolver
ensp
ENSP00000791086
resolver
enst
ENST00000636051
resolver
genesymbol
ING5
resolver
hgnc
HGNC:19421
resolver
uniprot
A0A1B0GW41
resolver
uniprot
A8K1P3
resolver
uniprot
Q53NU6
resolver
uniprot
Q57Z54
resolver
uniprot
Q9BS30
resolver
uniprot_entry
A0A1B0GW41_HUMAN
resolver
uniprot_entry
ING5_HUMAN
resolver
uniprot_sec
A8K1P3
resolver
uniprot_sec
Q53NU6
resolver
uniprot_sec
Q57Z54
resolver
uniprot_sec
Q9BS30
resolver
amino_acid_sequence
MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDFESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK
uniprot
proteins
function
FUNCTION: Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4 (PubMed:24065767). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator (PubMed:12750254, PubMed:16387653). Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner (PubMed:21750715). {ECO:0000269|PubMed:12750254, ECO:0000269|PubMed:16387653, ECO:0000269|PubMed:21750715, ECO:0000269|PubMed:24065767}.
uniprot
proteins
mass_dalton
27751
uniprot
proteins
protein_family
ING family
uniprot
proteins
pubmed
12750254
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16387653
uniprot
proteins
pubmed
16728974
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18623064
uniprot
proteins
pubmed
18794358
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
21750715
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24065767
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
240
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18794358}. Chromosome {ECO:0000269|PubMed:24065767}. Note=Localizes to transcription start sites. {ECO:0000269|PubMed:24065767}.
uniprot
proteins