Tlcd3b
entrez
68952
canonical
uniprot
Q7TNV1
canonical
ensembl
ENSMUSG00000058966
resolver
ensp
ENSMUSP00000078392
resolver
ensp
ENSMUSP00000095640
resolver
ensp
ENSMUSP00000145721
resolver
genesymbol
Tlcd3b
resolver
genesymbol_syn
Fam57b
resolver
uniprot
Q3V2R2
resolver
uniprot
Q561N3
resolver
uniprot
Q9CW26
resolver
uniprot_entry
TLC3B_MOUSE
resolver
uniprot_sec
Q3V2R2
resolver
uniprot_sec
Q561N3
resolver
uniprot_sec
Q9CW26
resolver
amino_acid_sequence
MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVSTSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGEDGTPRALGSTWAVVRGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFRPRGSPPPSPCQTQD
uniprot
proteins
ec_number
2.3.1.-
uniprot
proteins
function
FUNCTION: Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis. {ECO:0000269|PubMed:23275342}.
uniprot
proteins
mass_dalton
30778
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
23275342
uniprot
proteins
pubmed
33077892
uniprot
proteins
sequence_length
275
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Golgi apparatus membrane {ECO:0000269|PubMed:23275342}; Multi-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23275342}; Multi-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 3]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23275342}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 130..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 159..179; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins