Sod1
entrez
20655
canonical
uniprot
P08228
canonical
ensembl
ENSMUSG00000022982
resolver
ensp
ENSMUSP00000023707
resolver
enst
ENSMUST00000023707
resolver
genesymbol
Sod1
resolver
uniprot_entry
SODC_MOUSE
resolver
amino_acid_sequence
MAMKAVCVLKGDGPVQGTIHFEQKASGEPVVLSGQITGLTEGQHGFHVHQYGDNTQGCTSAGPHFNPHSKKHGGPADEERHVGDLGNVTAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ
uniprot
proteins
ec_number
1.15.1.1
uniprot
proteins
ec_number
1.8.-.-
uniprot
proteins
function
FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Catalyzes the oxidation of hydrogen sulfide (H2S) to sulfate, playing an important role in detoxifying H2S and limiting the accumulation of reactive sulfur species (RSS) such as persulfides and polysulfides. {ECO:0000250|UniProtKB:P00441}.
uniprot
proteins
mass_dalton
15943
uniprot
proteins
post_translational_modification
PTM: Palmitoylation helps nuclear targeting and decreases catalytic activity. {ECO:0000250|UniProtKB:P00441}.; PTM: Succinylation, adjacent to copper catalytic site, probably inhibits activity. Desuccinylation by SIRT5 enhances activity. {ECO:0000250|UniProtKB:P00441}.
uniprot
proteins
protein_family
Cu-Zn superoxide dismutase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
2022332
uniprot
proteins
pubmed
20727846
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21420488
uniprot
proteins
pubmed
22203986
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
2391363
uniprot
proteins
pubmed
29194436
uniprot
proteins
pubmed
3362683
uniprot
proteins
sequence_length
154
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P00441}. Nucleus {ECO:0000250|UniProtKB:P00441}.
uniprot
proteins