Pth2
entrez
114640
canonical
uniprot
Q91W27
canonical
ensembl
ENSMUSG00000038300
resolver
ensp
ENSMUSP00000041047
resolver
ensp
ENSMUSP00000147367
resolver
enst
ENSMUST00000042754
resolver
enst
ENSMUST00000210086
resolver
genesymbol
Pth2
resolver
genesymbol_syn
Tip39
resolver
genesymbol_syn
Tipf39
resolver
uniprot
A0A1B0GR43
resolver
uniprot
Q91ZA0
resolver
uniprot_entry
A0A1B0GR43_MOUSE
resolver
uniprot_entry
TIP39_MOUSE
resolver
uniprot_sec
Q91ZA0
resolver
amino_acid_sequence
METCQMSRSPRERLLLLLLLLLLVPWGTGPASGVALPLAGVFSLRAPGRAWAGLGSPLSRRSLALADDAAFRERARLLAALERRRWLDSYMQKLLLLDAP
uniprot
proteins
function
FUNCTION: Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action of PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits. {ECO:0000269|PubMed:11818570, ECO:0000269|PubMed:11861531, ECO:0000269|PubMed:12084532}.
uniprot
proteins
mass_dalton
11022
uniprot
proteins
protein_family
Parathyroid hormone family
uniprot
proteins
pubmed
11818570
uniprot
proteins
pubmed
11861531
uniprot
proteins
pubmed
12084532
uniprot
proteins
pubmed
12098667
uniprot
proteins
pubmed
12559132
uniprot
proteins
sequence_length
100
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins