Hnrnpa1
entrez
29578
canonical
uniprot
P04256
canonical
ensembl
ENSRNOG00000036839
resolver
ensp
ENSRNOP00000052160
resolver
ensp
ENSRNOP00000074880
resolver
ensp
ENSRNOP00000094714
resolver
enst
ENSRNOT00000091596
resolver
enst
ENSRNOT00000113929
resolver
genesymbol
Hnrnpa1
resolver
genesymbol_syn
Hnrpa1
resolver
uniprot
A0A0G2K968
resolver
uniprot
A0A8I6ALC1
resolver
uniprot
F7FEZ6
resolver
uniprot
Q5I0M7
resolver
uniprot_entry
A0A0G2K968_RAT
resolver
uniprot_entry
A0A8I6ALC1_RAT
resolver
uniprot_entry
Q5I0M7_RAT
resolver
uniprot_entry
ROA1_RAT
resolver
uniprot_sec
F7FEZ6
resolver
amino_acid_sequence
MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALCKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF
uniprot
proteins
function
FUNCTION: Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and modulation of splice site selection. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform. Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1. May bind to specific miRNA hairpins. {ECO:0000250|UniProtKB:P09651}.
uniprot
proteins
mass_dalton
34212
uniprot
proteins
post_translational_modification
PTM: Sumoylated. {ECO:0000250}.
uniprot
proteins
pubmed
24098712
uniprot
proteins
pubmed
2447078
uniprot
proteins
pubmed
3005291
uniprot
proteins
sequence_length
320
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P09651}. Cytoplasm {ECO:0000250|UniProtKB:P09651}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes. {ECO:0000250|UniProtKB:P09651}.
uniprot
proteins