Sftpa1
entrez
24773
canonical
uniprot
P08427
canonical
ensembl
ENSRNOG00000011438
resolver
ensp
ENSRNOP00000039850
resolver
genesymbol
Sftpa1
resolver
genesymbol_syn
Sftp-1
resolver
genesymbol_syn
Sftp1
resolver
genesymbol_syn
Sftpa
resolver
uniprot_entry
SFTPA_RAT
resolver
amino_acid_sequence
MSLCSLAFTLFLTVVAGIKCNVTDVCAGSPGIPGAPGNHGLPGRDGRDGVKGDPGPPGPMGPPGGMPGLPGRDGLPGAPGAPGERGDKGEPGERGLPGFPAYLDEELQTELYEIKHQILQTMGVLSLQGSMLSVGDKVFSTNGQSVNFDTIKEMCTRAGGNIAVPRTPEENEAIASIAKKYNNYVYLGMIEDQTPGDFHYLDGASVNYTNWYPGEPRGQGKEKCVEMYTDGTWNDRGCLQYRLAVCEF
uniprot
proteins
function
FUNCTION: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages. {ECO:0000250|UniProtKB:P35242}.
uniprot
proteins
mass_dalton
26289
uniprot
proteins
protein_family
SFTPA family
uniprot
proteins
pubmed
12913002
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2901856
uniprot
proteins
pubmed
3579914
uniprot
proteins
pubmed
7491978
uniprot
proteins
sequence_length
248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8IWL2}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q8IWL2}. Secreted, extracellular space, surface film {ECO:0000250|UniProtKB:Q8IWL2}.
uniprot
proteins