PCBP1
entrez
5093
canonical
uniprot
Q15365
canonical
ensembl
ENSG00000169564
resolver
ensp
ENSP00000305556
resolver
enst
ENST00000303577
resolver
genesymbol
PCBP1
resolver
genesymbol_syn
HEL-S-85
resolver
hgnc
HGNC:8647
resolver
uniprot
Q13157
resolver
uniprot
Q14975
resolver
uniprot
Q53SS8
resolver
uniprot_entry
PCBP1_HUMAN
resolver
uniprot_entry
Q53SS8_HUMAN
resolver
uniprot_sec
Q13157
resolver
uniprot_sec
Q14975
resolver
amino_acid_sequence
MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS
uniprot
proteins
function
FUNCTION: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:15731341, PubMed:7556077, PubMed:7607214, PubMed:8152927). Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity). {ECO:0000250|UniProtKB:P60335, ECO:0000269|PubMed:15731341, ECO:0000269|PubMed:7556077, ECO:0000269|PubMed:7607214, ECO:0000269|PubMed:8152927}.; FUNCTION: (Microbial infection) In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD. {ECO:0000269|PubMed:12414943}.
uniprot
proteins
mass_dalton
37498
uniprot
proteins
post_translational_modification
PTM: Phosphorylated; lowers poly(rC)-binding activity. {ECO:0000269|PubMed:7607214}.
uniprot
proteins
pubmed
12414943
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15731341
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17924679
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
7556077
uniprot
proteins
pubmed
7607214
uniprot
proteins
pubmed
8152927
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:7607214}. Cytoplasm {ECO:0000269|PubMed:7607214}. Note=Loosely bound in the nucleus (PubMed:7607214). May shuttle between the nucleus and the cytoplasm (PubMed:7607214). {ECO:0000269|PubMed:7607214}.
uniprot
proteins