Dpep2
entrez
319446
canonical
uniprot
Q8C255
canonical
ensembl
ENSMUSG00000053687
resolver
ensembl
ENSMUSG00000115067
resolver
ensp
ENSMUSP00000034373
resolver
ensp
ENSMUSP00000080659
resolver
ensp
ENSMUSP00000113877
resolver
genesymbol
Dpep2
resolver
genesymbol_syn
Mbd2
resolver
uniprot
Q3TAV9
resolver
uniprot
Q3TBF7
resolver
uniprot
Q3TBK3
resolver
uniprot
Q3TBM9
resolver
uniprot
Q7TQ53
resolver
uniprot_entry
DPEP2_MOUSE
resolver
uniprot_sec
Q3TAV9
resolver
uniprot_sec
Q3TBF7
resolver
uniprot_sec
Q3TBK3
resolver
uniprot_sec
Q3TBM9
resolver
uniprot_sec
Q7TQ53
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by L-penicillamine. {ECO:0000269|PubMed:12738806}.
uniprot
proteins
amino_acid_sequence
MSLTGLKGHWVLGHGLSVFLLVLLLLGPSQPLIWTQTKPGFSGASTTSSIPRALTKPDISSIPTTPGNPNFPDLRDRARALMQEFPLIDGHNDMPLVLRQFYQNGLQDANLRNFTHGQTSLDRLKDGLVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRICASYSELELVTSVKALNSTQKLACLIGVEGGHSLDNSLAVLRSFYLLGVRYLTLTHTCNTPWAETSSKGVHAFYSSVTGLTSFGEKVVAEMNRLGMMVDLSHVSDAAARRALEVSQAPVIFSHSAARAVCPNARNLPDDLLQLLKKNGGIVMVTFSVGVLPCNPLANVSTVADHFDHIRSVIGSEFIGIGGDYDGTKQFPQGLEDVSTYPVLIEELLRRGWNEQELQGILRGNLLRVFRQVEQVRDKSKWQSPLEDMIPEEQLDSACHSALRPQKQHPEKNQPETPEYHILKFSHSKSSPHIVPSLAIVATLLGLIV
uniprot
proteins
ec_number
3.4.13.19
uniprot
proteins
function
FUNCTION: Dipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) (PubMed:12738806). Hydrolyzes cystinyl-bis-glycine (By similarity). {ECO:0000250|UniProtKB:Q9H4A9, ECO:0000269|PubMed:12738806}.; FUNCTION: Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF-kappa-B inflammatory signaling pathway. {ECO:0000269|PubMed:30899700}.
uniprot
proteins
mass_dalton
52664
uniprot
proteins
protein_family
Metallo-dependent hydrolases superfamily
uniprot
proteins
protein_family
Peptidase M19 family
uniprot
proteins
pubmed
12738806
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
30899700
uniprot
proteins
sequence_length
478
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:12738806}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:12738806}.
uniprot
proteins