Pakap
entrez
677884
canonical
uniprot
O54931
canonical
ensembl
ENSMUSG00000038729
resolver
ensembl
ENSMUSG00000089945
resolver
ensembl
ENSMUSG00000090053
resolver
ensp
ENSMUSP00000048678
resolver
ensp
ENSMUSP00000099967
resolver
ensp
ENSMUSP00000099968
resolver
ensp
ENSMUSP00000103224
resolver
ensp
ENSMUSP00000117466
resolver
genesymbol
Pakap
resolver
genesymbol_syn
Akap2
resolver
genesymbol_syn
Palm2
resolver
genesymbol_syn
Palm2akap2
resolver
uniprot
A2APJ4
resolver
uniprot
O54932
resolver
uniprot
O54933
resolver
uniprot
Q8BR92
resolver
uniprot
Q8C5W1
resolver
uniprot
Q8C9L6
resolver
uniprot_entry
AKAP2_MOUSE
resolver
uniprot_entry
Q8C9L6_MOUSE
resolver
uniprot_sec
A2APJ4
resolver
uniprot_sec
O54932
resolver
uniprot_sec
O54933
resolver
uniprot_sec
Q8BR92
resolver
uniprot_sec
Q8C5W1
resolver
amino_acid_sequence
MAEAELHKERLQAIAEKRKRQTEIEGKRRQLDEQVLLLQHSKSKVLREKWLLQGVPAGTAEEEEARRRQSEEDEFKVKQLEDNIQRLEQEIQALESEESQISAKEQIILEKLKETEKSFKDLQKSFSTADGASGWSTVLLQGDELTADPIGTNADMAIQKPPQLSEDANQLRSKQDNCGDSRLEPAASSLSPDHKNMEIGVSVAECKSVPGVTSTPHSKDHSSPFYSPSHNGLLADHHESLDNDVAREIQYLDEVLEANCCDSSVDGTYNGISSPEPGAAILVSSLGSPAHSVTEAEPTEKASGRQVPPHIELSRSPSDRMAEGERANGHSTDQPQDLLGNSLQAPASPSSSTSSHCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEEDEREKEQFCVRKVRPSEEMIELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHRKYKERKEKRAQQEQLQLQQQQQQQLQQQQLQQQQLQQQQLQQQLQQQQLSTSQPCTAPAAHKHLDGIEHTKEDVVTEQIDFSAARKQFQLMENSRQTLAKGQSTPRLFSIKPYYKPLGSIHSDKPPTILRPATVGGTLEDGGTQAAKEQKAPCVSESQSAGAGPANAATQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDEDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETPSALQENSLADFSLPQTPQTDNPSEGREGVSKSFSDHGFYSPSSTLGDSPSVDDPLEYQAGLLVQNAIQQAIAEQVDKAEAHTSKEGSEQQEPEATVEEAGSQTPGSEKPQGMFAPPQVSSPVQEKRDILPKNLPAEDRALREKGPSQPPTAAQPSGPVNMEETRPEGGYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVRQSTPSPRAKNAPSLPSRTTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEEDNE
uniprot
proteins
function
FUNCTION: Binds to regulatory subunit (RII) of protein kinase A (PubMed:9497389). May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (PubMed:9497389). Binds tp and modulates the structure of the actin cytoskeleton (PubMed:9497389). {ECO:0000269|PubMed:9497389}.
uniprot
proteins
mass_dalton
120791
uniprot
proteins
mutagenesis
MUTAGEN 786; /note="A->S: No effect on binding to RII."; /evidence="ECO:0000269|PubMed:9497389"; MUTAGEN 794; /note="I->A: Reduces binding to RII."; /evidence="ECO:0000269|PubMed:9497389
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9497389
uniprot
proteins
sequence_length
1089
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:9497389}; Lipid-anchor, GPI-like-anchor {ECO:0000269|PubMed:9497389}; Cytoplasmic side {ECO:0000269|PubMed:9497389}. Note=Accumulates near the inner, apical surface of highly polarized epithelium in tubules of nephrons. {ECO:0000269|PubMed:9497389}.
uniprot
proteins