Psmd7
entrez
17463
canonical
uniprot
P26516
canonical
ensembl
ENSMUSG00000039067
resolver
ensp
ENSMUSP00000041968
resolver
enst
ENSMUST00000044106
resolver
genesymbol
Psmd7
resolver
genesymbol_syn
Mov-34
resolver
genesymbol_syn
Mov34
resolver
uniprot
A1L3B8
resolver
uniprot
Q3TW61
resolver
uniprot
Q8C0I8
resolver
uniprot_entry
A1L3B8_MOUSE
resolver
uniprot_entry
PSMD7_MOUSE
resolver
uniprot_sec
Q3TW61
resolver
uniprot_sec
Q8C0I8
resolver
amino_acid_sequence
MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVASGKLPINHQIIYQLQDVFNLLPDASLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKERKDDKEKEKSDAAKKEEKKEKK
uniprot
proteins
disease_involvement
DISEASE: Note=Disruption of the Mov-34 locus is a recessive embryonic lethal mutation. {ECO:0000305|PubMed:2209467}.
uniprot
proteins
function
FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. {ECO:0000250|UniProtKB:P51665}.
uniprot
proteins
mass_dalton
36540
uniprot
proteins
protein_family
Peptidase M67A family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
1837787
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2209467
uniprot
proteins
pubmed
23576753
uniprot
proteins
sequence_length
321
uniprot
proteins