SSU72
entrez
29101
canonical
uniprot
Q9NP77
canonical
ensembl
ENSG00000160075
resolver
ensp
ENSP00000291386
resolver
genesymbol
SSU72
resolver
hgnc
HGNC:25016
resolver
uniprot
Q9BZS6
resolver
uniprot
Q9H933
resolver
uniprot_entry
SSU72_HUMAN
resolver
uniprot_sec
Q9BZS6
resolver
uniprot_sec
Q9H933
resolver
amino_acid_sequence
MPSSPLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDLFDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFEEKSGRTFLHTVCFY
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK. {ECO:0000269|PubMed:15659578, ECO:0000269|PubMed:20861839, ECO:0000269|PubMed:23070812}.
uniprot
proteins
mass_dalton
22574
uniprot
proteins
mutagenesis
MUTAGEN 12; /note="C->S: Abolishes phosphatase activity."; /evidence="ECO:0000269|PubMed:15659578
uniprot
proteins
protein_family
SSU72 phosphatase family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15659578
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
20861839
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23070812
uniprot
proteins
pubmed
29158257
uniprot
proteins
sequence_length
194
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=Predominantly in the cytosol.
uniprot
proteins