SUGT1
entrez
10910
canonical
uniprot
Q9Y2Z0
canonical
ensembl
ENSG00000165416
resolver
ensp
ENSP00000308067
resolver
ensp
ENSP00000367208
resolver
ensp
ENSP00000596069
resolver
genesymbol
SUGT1
resolver
hgnc
HGNC:16987
resolver
uniprot
A2A303
resolver
uniprot
A8K7W3
resolver
uniprot
B4DYC6
resolver
uniprot
Q5JAK5
resolver
uniprot
Q5TAM6
resolver
uniprot
Q6VXY6
resolver
uniprot_entry
A8K7W3_HUMAN
resolver
uniprot_entry
B4DYC6_HUMAN
resolver
uniprot_entry
SGT1_HUMAN
resolver
uniprot_sec
A2A303
resolver
uniprot_sec
Q5JAK5
resolver
uniprot_sec
Q5TAM6
resolver
uniprot_sec
Q6VXY6
resolver
amino_acid_sequence
MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSESEVWTHQSKIKYDWYQTESQVVITLMIKNVQKNDVNVEFSEKELSALVKLPSGEDYNLKLELLHPIIPEQSTFKVLSTKIEIKLKKPEAVRWEKLEGQGDVPTPKQFVADVKNLYPSSSPYTRNWDKLVGEIKEEEKNEKLEGDAALNRLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTNWSDVGKRKVEINPPDDMEWKKY
uniprot
proteins
function
FUNCTION: May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
uniprot
proteins
mass_dalton
41024
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex. {ECO:0000269|PubMed:21864708}.
uniprot
proteins
protein_family
SGT1 family
uniprot
proteins
pubmed
10445024
uniprot
proteins
pubmed
12665801
uniprot
proteins
pubmed
12746458
uniprot
proteins
pubmed
14761955
uniprot
proteins
pubmed
15018354
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15346769
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21864708
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25114211
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
365
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21864708}. Nucleus {ECO:0000269|PubMed:21864708}. Note=Translocates to the nucleus upon heat shock, requiring S100A6.
uniprot
proteins