Ptdss2
entrez
293620
canonical
uniprot
B2GV22
canonical
ensembl
ENSRNOG00000015912
resolver
ensembl
ENSRNOG00055029077
resolver
ensembl
ENSRNOG00060027976
resolver
ensembl
ENSRNOG00065018977
resolver
ensp
ENSRNOP00000021925
resolver
ensp
ENSRNOP00055041443
resolver
ensp
ENSRNOP00060040503
resolver
ensp
ENSRNOP00065025482
resolver
enst
ENSRNOT00000021925
resolver
enst
ENSRNOT00055050357
resolver
enst
ENSRNOT00060048588
resolver
enst
ENSRNOT00065031928
resolver
genesymbol
Ptdss2
resolver
uniprot_entry
PTSS2_RAT
resolver
amino_acid_sequence
MRRGERRVAGGSGSESPLLEGRRSTESEVYDDGTNTFFWRAHTLTVLFILTCALGYVTLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQTVHDGRQFLKYVDPRLGVPLPERDYGGNCLIYDADNKTDPFHNIWDKLDGFVPAHFIGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLLCNGLGIYCGMKTLEWLSLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSWVRFEWKPASSLHRWLAVCGIILVFLLAELNTFYLKFVLWMPPEHYLVLLRLVFFVNVGGVAMREIYDFMDELKPHRKLGQQAWLVAAITVTELLIVVKYDPHTLTLSLPFYISQCWTLGSILVLTWTVWRFFLRDITMRYKETRRQKQQSHQAINNGDGHPGPEDDLPGTGTAEEEGTTNDGVPAEEGPSAAS
uniprot
proteins
ec_number
2.7.8.29
uniprot
proteins
function
FUNCTION: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine to form phosphatidylserine (By similarity). Lacks phosphatidylcholine-dependent base-exchange activity (By similarity). Can utilize both phosphatidylethanolamine (PE) plasmalogen and diacyl PE as substrate and the latter is six times better utilized, indicating the importance of an ester linkage at the sn-1 position (By similarity). Although it shows no sn-1 fatty acyl preference, exhibits significant preference towards docosahexaenoic acid (22:6n-3) compared with 18:1 or 20:4 at the sn-2 position (By similarity). {ECO:0000250|UniProtKB:Q9Z1X2}.
uniprot
proteins
mass_dalton
54722
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; phosphatidylserine biosynthesis.
uniprot
proteins
protein_family
Phosphatidyl serine synthase family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
471
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Z1X2}; Multi-pass membrane protein {ECO:0000255}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250|UniProtKB:Q9Z1X2}.
uniprot
proteins
transmembrane_region
TRANSMEM 41..61; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 75..95; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 105..125; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 292..312; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 355..375; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 382..402; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins