PGAM1
entrez
5223
canonical
uniprot
P18669
canonical
ensembl
ENSG00000171314
resolver
ensp
ENSP00000359991
resolver
enst
ENST00000334828
resolver
genesymbol
PGAM1
resolver
genesymbol_syn
HEL-S-35
resolver
genesymbol_syn
PGAMA
resolver
hgnc
HGNC:8888
resolver
uniprot
B7Z9E5
resolver
uniprot
Q6FHU2
resolver
uniprot
Q9BWC0
resolver
uniprot_entry
B7Z9E5_HUMAN
resolver
uniprot_entry
PGAM1_HUMAN
resolver
uniprot_entry
Q6FHU2_HUMAN
resolver
uniprot_sec
Q9BWC0
resolver
amino_acid_sequence
MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK
uniprot
proteins
ec_number
5.4.2.11
uniprot
proteins
ec_number
5.4.2.4
uniprot
proteins
function
FUNCTION: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate, a crucial step in glycolysis, by using 2,3-bisphosphoglycerate (PubMed:23653202). Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate (PubMed:23653202). {ECO:0000269|PubMed:23653202}.
uniprot
proteins
mass_dalton
28804
uniprot
proteins
post_translational_modification
PTM: Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme. {ECO:0000269|PubMed:22157007}.
uniprot
proteins
protein_family
BPG-dependent PGAM subfamily
uniprot
proteins
protein_family
Phosphoglycerate mutase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15883004
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22157007
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23653202
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
2846553
uniprot
proteins
pubmed
2846554
uniprot
proteins
pubmed
9150946
uniprot
proteins
sequence_length
254
uniprot
proteins