Txn2
entrez
79462
canonical
uniprot
P97615
canonical
ensembl
ENSRNOG00055031594
resolver
ensembl
ENSRNOG00060029554
resolver
ensembl
ENSRNOG00065032853
resolver
ensp
ENSRNOP00055045220
resolver
ensp
ENSRNOP00060042697
resolver
ensp
ENSRNOP00065046460
resolver
enst
ENSRNOT00055054713
resolver
enst
ENSRNOT00060051329
resolver
enst
ENSRNOT00065056481
resolver
genesymbol
Txn2
resolver
genesymbol_syn
Trx2
resolver
uniprot_entry
THIOM_RAT
resolver
amino_acid_sequence
MAQRLLLRRFLTSVISRKPPQGVWASLTSTSLQTPPYNAGGLTGTPSPARTFHTTRVCSTTFNVQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKLIG
uniprot
proteins
function
FUNCTION: Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability (By similarity). Is involved in various redox reactions including the reduction of protein disulfide bonds, through the reversible oxidation of its active center dithiol to a disulfide (PubMed:9006939). {ECO:0000250|UniProtKB:Q99757, ECO:0000269|PubMed:9006939}.
uniprot
proteins
mass_dalton
18232
uniprot
proteins
protein_family
Thioredoxin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9006939
uniprot
proteins
sequence_length
166
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:9006939}.
uniprot
proteins