DNA damage
cv_term_accession
KW-0227
canonical
uniprot_keyword
KW-0227
canonical
name
DNA damage
uniprot
synonym
DNA damage response
uniprot
synonym
Response to DNA damage stimulus
uniprot
definition
Protein induced by DNA damage or protein involved in the response to DNA damage. Drug- or radiation-induced injuries in DNA introduce deviations from its normal double-helical conformation. These changes include structural distortions which interfere with replication and transcription, as well as point mutations which disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. Response to DNA damage results in either repair or tolerance.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords