Fgd5
entrez
232237
canonical
uniprot
Q80UZ0
canonical
ensembl
ENSMUSG00000034037
resolver
ensp
ENSMUSP00000086748
resolver
ensp
ENSMUSP00000184199
resolver
enst
ENSMUST00000089334
resolver
genesymbol
Fgd5
resolver
uniprot
E9QKY4
resolver
uniprot
Q8BHM5
resolver
uniprot_entry
E9QKY4_MOUSE
resolver
uniprot_entry
FGD5_MOUSE
resolver
uniprot_sec
Q8BHM5
resolver
amino_acid_sequence
MGSPESEVSPDVQEQEAATDNPEVFEEDSADAAEGEDQIEQEEPPNCDEEAYNRDAAAATMQVGEDLGEEGDHVQEDPAEESCQIIPFESDSVEEDFSPTLTENPYEIFPTESTSFCNNTYSLDESANGHEPVCEICVEEVPGVGPPLNQHDSLPDGSGEDSPVVPDVVVVPENEGPVDDALSSPYVMGVGLLSLGEGAQSDTQAASGTLSGYSTWEEGDSEGGQVPVDRKNIATRARPHSGKVAGHVPETVLEETGPETCSSGMGIRDTSDEVRKIGILPEGKPPECVRALPAKPRAFTLYPRSFSVEGRESPLSMFREPEGAGLDSHRVRRKEDNLSLPGAIGSSGSFSQRSHLPSSGTSTPSSVVDIPPPFDLACITKKPITKSSPSLLIDGDTLEKASKKKKSSFKRFLELTFRKKTESKVHVDMNLSSSRSSSESSYHGPARVLELDRRSLSNSPQLKCRTGKLRASDSPAALIFYRDSKRKGVPFSRTVSRVESFEDRSRPPFLPLPLTKPRSISFPNADTSDYENIPAMNSDYENIQIPPRRPVRTGTFTKLFEEQSRALSTANENDGYVDMSSFNAFESKQQSSEQEAESAYTEPYKVCPISAAPREDLTSDEEQGSSEEEDSASRDPSLSHKGEGQSRALVIAQELLSSEKAYVQMLQHLSLDFHGAVLRALENVEQEGREPLAQEELRQGLRELPAICDLHQGILESLEQRLGDCGEGQPQVADIFLAREQEFEHHAAHILQFDRYLGLLAESCLLSPRLATTVREFEQSSQGGGQSMKHRMLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQSALTLISKVTDRANESMEQGENLQKLVHIEYSVRGQGDLLQPGREFLKEGTLMRVRGKSRHPRHLFLMNDTLLYTHPQKDGKYRLKSSLPVANMKVSRPVMDKVPYALKIETPESCLTLSASSCAERDEWHYCLSRALPEDYKTQALAAFHHSVEIRERLGISLGERLPTLVPVTHAMMCMNCGCDFSLTVRRHHCHACGKIVCRNCSRNKYPLKCLKNRMAKVCDGCFRELKLRNGPVPGSMRERPVSMSFPLSSSRFSSGSALSSVFQSISPSTFKKQKKVPSALSEVAASGEGSAISGYLSRCKSGKRRWKKLWLVIKGKVLYTYLASEDKVAMESIPLLGFTIAPEKEEGSSEVGPVFHLYHKKTLFYSFKAEDSNSAQRWMEAMEDASVL
uniprot
proteins
function
FUNCTION: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
134719
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22328776
uniprot
proteins
sequence_length
1219
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, ruffle membrane {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Early endosome {ECO:0000250}. Note=In peripheral membrane ruffles, colocalizes with F-actin. {ECO:0000250}.
uniprot
proteins