D2hgdh
entrez
98314
canonical
uniprot
Q8CIM3
canonical
ensembl
ENSMUSG00000073609
resolver
ensp
ENSMUSP00000095235
resolver
ensp
ENSMUSP00000108502
resolver
ensp
ENSMUSP00000282702
resolver
ensp
ENSMUSP00000282709
resolver
ensp
ENSMUSP00000282712
resolver
enst
ENSMUST00000097633
resolver
enst
ENSMUST00000112881
resolver
genesymbol
D2hgdh
resolver
uniprot
E9QLL1
resolver
uniprot
E9QN44
resolver
uniprot
Q149H0
resolver
uniprot
Q3TDF5
resolver
uniprot
Q8BU06
resolver
uniprot_entry
D2HDH_MOUSE
resolver
uniprot_entry
E9QN44_MOUSE
resolver
uniprot_sec
E9QLL1
resolver
uniprot_sec
Q149H0
resolver
uniprot_sec
Q3TDF5
resolver
uniprot_sec
Q8BU06
resolver
activity_regulation
ACTIVITY REGULATION: Activated by zinc and cobalt ions. {ECO:0000250|UniProtKB:Q8N465}.
uniprot
proteins
amino_acid_sequence
MVLPLVSRWSARVLWASPGWRRTYTQRACVGLKRLGCPRGVYSPLAHRAYSVVAGGPEVTLTPERYPVQRLPFSTVSEEDLAAFECIIPGRVITDPEQLQTCNVDWLKTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVPVFDEVILSTALMNQVISFHDVSGILVCQAGCVLEELSRYVQERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTILNCLTSLRKDNTGYDLKQMFIGSEGTLGVITAVSIVCPPRPKAVNVAFLGCPGFAEVLQTFRTCRGMLGEILSAFEFMDTECMQLVGQHLQLTNPVQESPFYVLVETSGSSAGHDAEKLTNVLEQVLNSGLVTDGTMATDQRKVQMLWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRLGPRAKHVVGYGHLGDGNLHLNVTAEAFSRELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKDVLGYSKPPVAVTLMQQLKAMLDPEGILNPYKTLPAQA
uniprot
proteins
ec_number
1.1.99.39
uniprot
proteins
function
FUNCTION: Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate (By similarity). Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC) (By similarity). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC (By similarity). {ECO:0000250|UniProtKB:Q8N465}.
uniprot
proteins
mass_dalton
58576
uniprot
proteins
protein_family
FAD-binding oxidoreductase/transferase type 4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
uniprot
proteins