Hp
entrez
24464
canonical
uniprot
P06866
canonical
ensembl
ENSRNOG00000014964
resolver
ensembl
ENSRNOG00055020965
resolver
ensembl
ENSRNOG00060011558
resolver
ensembl
ENSRNOG00065012465
resolver
ensp
ENSRNOP00000085960
resolver
genesymbol
Hp
resolver
uniprot
Q5EBB4
resolver
uniprot
Q7TP23
resolver
uniprot_entry
HPT_RAT
resolver
uniprot_sec
Q5EBB4
resolver
uniprot_sec
Q7TP23
resolver
amino_acid_sequence
MRALGAVVTLLLWGQLFAVELGNDATDIEDDSCPKPPEIANGYVEHLVRYRCRQFYKLQTEGDGIYTLNSEKQWVNPAAGDKLPKCEAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQWLLTTAQNLFLNHSENATAKDIAPTLTLYVGKNQLVEIEKVVLHPERSVVDIGLIKLKQKVLVTEKVMPICLPSKDYVAPGRMGYVSGWGRNVNFRFTERLKYVMLPVADQEKCELHYEKSTVPEKKGAVSPVGVQPILNKHTFCAGLTKYEEDTCYGDAGSAFAVHDTEEDTWYAAGILSFDKSCAVAEYGVYVRATDLKDWVQETMAKN
uniprot
proteins
function
FUNCTION: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
38563
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2320005
uniprot
proteins
pubmed
6204979
uniprot
proteins
pubmed
6863267
uniprot
proteins
pubmed
975782
uniprot
proteins
sequence_length
347
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins