Taar6
entrez
215855
canonical
uniprot
Q5QD13
canonical
ensembl
ENSMUSG00000045111
resolver
ensp
ENSMUSP00000097603
resolver
enst
ENSMUST00000057080
resolver
genesymbol
Taar6
resolver
genesymbol_syn
Gm228
resolver
uniprot_entry
TAAR6_MOUSE
resolver
amino_acid_sequence
MGSNSSPPTVLQLCYENVTGSCVKTPYSPGSRVILYAVFGFGAVLAVFGNLMVMISILHFKQLHSPTNFLIASLACADFGVGISVMPFSMVRSIESCWYFGRSFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICIGVSWILPLVYSGAVFYTGVYDDGLEELSSALNCVGGCQVVVNQNWVLIDFLSFLIPTLVMIILYGNIFLVARQQAKKIENIGSKTESSSESYKARVARRERKAAKTLGITVVAFMISWLPYSIDSLVDAFMGFITPAYIYEICVWCAYYNSAMNPLIYALFYPWFKKAIKVIMSGQVFKNSSATMNLFSEQI
uniprot
proteins
function
FUNCTION: Olfactory receptor specific for trace amines, such as beta-phenylethylamine (beta-PEA) (PubMed:37225986). Trace amine compounds are enriched in animal body fluids and act on trace amine-associated receptors (TAARs) to elicit both intraspecific and interspecific innate behaviors (PubMed:37225986). Beta-PEA-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS) (PubMed:37225986). {ECO:0000269|PubMed:37225986}.
uniprot
proteins
mass_dalton
38279
uniprot
proteins
mutagenesis
MUTAGEN 113; /note="V->T: Promotes trace-amine receptor activity toward spermidine."; /evidence="ECO:0000269|PubMed:37225986
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15718104
uniprot
proteins
pubmed
16878137
uniprot
proteins
pubmed
22837392
uniprot
proteins
pubmed
23624375
uniprot
proteins
pubmed
37225986
uniprot
proteins
sequence_length
345
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q96RI8}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 33..53; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 69..89; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 108..128; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 148..168; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 203..223; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 260..276; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 283..302; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins