Cipc
entrez
217732
canonical
uniprot
Q8R0W1
canonical
ensembl
ENSMUSG00000034157
resolver
ensp
ENSMUSP00000038630
resolver
ensp
ENSMUSP00000140266
resolver
enst
ENSMUST00000038369
resolver
enst
ENSMUST00000189246
resolver
genesymbol
Cipc
resolver
genesymbol_syn
Kiaa1737
resolver
uniprot
A0A087WQN1
resolver
uniprot
Q3TUN6
resolver
uniprot
Q3U423
resolver
uniprot
Q3UFM0
resolver
uniprot
Q80T99
resolver
uniprot
Q8C680
resolver
uniprot
Z4YJJ0
resolver
uniprot_entry
CIPC_MOUSE
resolver
uniprot_entry
Z4YJJ0_MOUSE
resolver
uniprot_sec
A0A087WQN1
resolver
uniprot_sec
Q3TUN6
resolver
uniprot_sec
Q3U423
resolver
uniprot_sec
Q3UFM0
resolver
uniprot_sec
Q80T99
resolver
uniprot_sec
Q8C680
resolver
amino_acid_sequence
MRLLTRRAGHGAATLALRVIHMQRVPVLRLPAILDMERKIPSRESPRRLSAKPGRGTEMKKLARPLGVVAADSDKDSGFSDGSSECLSSAEQMESEDMLSALGCKREDKRRQPSKAADTALPTLPPMVVMKSVLVKQGSSSSQLQSWTVQPSFEVISAQPQLFVLHPPVPSPVSSCQTGEKKSESRNYLPILNSYTKIAPHPGKRGLNSEDRGTSGVSKKLCTERPGPSLSSSEPAKTGRVLSSPSTPAPPSSKLTEDSTLQGVPSLGAGGSPQTLQPVSSSHVAKAPSLTLASPASPVCASDSTLHGLESSSPLSPLSASYTSPLWAAEHLCRSPDIFSEQRQNKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQAELDQLKEQTQMFIEATKSRAPQAWAKLQASLTSGSSHSGSDLDTLSDHPDV
uniprot
proteins
function
FUNCTION: Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate BMAL1-dependent phosphorylation of CLOCK (PubMed:17310242, PubMed:19414601). However, the physiological relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock (PubMed:25862660). {ECO:0000269|PubMed:17310242, ECO:0000269|PubMed:19414601, ECO:0000269|PubMed:25862660}.
uniprot
proteins
mass_dalton
46320
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17310242
uniprot
proteins
pubmed
19414601
uniprot
proteins
pubmed
25862660
uniprot
proteins
sequence_length
432
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17310242}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9C0C6}. Note=Predominantly localizes to the nucleus, where it co-localizes with CLOCK. At the G1/S boundary, partially translocated to the cytosol. {ECO:0000250|UniProtKB:Q9C0C6, ECO:0000269|PubMed:17310242}.
uniprot
proteins