Gins2
entrez
272551
canonical
uniprot
Q9D600
canonical
ensembl
ENSMUSG00000031821
resolver
ensp
ENSMUSP00000034278
resolver
enst
ENSMUST00000034278
resolver
genesymbol
Gins2
resolver
genesymbol_syn
Psf2
resolver
uniprot
Q8BMT2
resolver
uniprot_entry
PSF2_MOUSE
resolver
uniprot_sec
Q8BMT2
resolver
amino_acid_sequence
MDAAEVEFLAEKELVTIIPNFSLDKIYLIGGDLGPFNPGLPVDVPLWLAINLKQRQKCRLLPPEWMDVEKLEQMRDEERKEETFTPVPSPHYMEITKLLLNHASDNIPKADTIRTLIKDLWDTRMAKLRVSADSFVRQQEAHAKLDNLTLMEISSSGAFLTQALNHMYKLRTNLQPSESTQSQDF
uniprot
proteins
function
FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. {ECO:0000250|UniProtKB:Q9Y248}.
uniprot
proteins
mass_dalton
21236
uniprot
proteins
protein_family
GINS2/PSF2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
185
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y248}. Chromosome {ECO:0000250|UniProtKB:Q9Y248}. Note=Associates with chromatin. {ECO:0000250|UniProtKB:Q9Y248}.
uniprot
proteins