Trem3
entrez
58218
canonical
uniprot
Q9JKE1
canonical
ensembl
ENSMUSG00000041754
resolver
ensp
ENSMUSP00000044478
resolver
enst
ENSMUST00000048065
resolver
genesymbol
Trem3
resolver
uniprot_entry
TREM3_MOUSE
resolver
amino_acid_sequence
MSPLLLWLGLMLCVSGLQAGDEEEHKCFLEGENLTLTCPYNIMLYSLSLKAWQRVRSHGSPETLVLTNTRKADFNVARAGKYLLEDYPTESVVKVTVTGLQRQDVGLYQCVVYLSPDNVIILRQRIRLAWCQGKPVMVIVLTCGFILNKGLVFSVLFVFLCKAGPKVLQPSKTSKVQGVSEKQ
uniprot
proteins
function
FUNCTION: Forms a receptor signaling complex with TYROBP/DAP12 which mediates activation of macrophages as part of the innate immune response. {ECO:0000269|PubMed:11754004}.
uniprot
proteins
mass_dalton
20452
uniprot
proteins
pubmed
11754004
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
183
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11754004}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 139..159; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins