Twf1
entrez
315265
canonical
uniprot
Q5RJR2
canonical
ensembl
ENSRNOG00000022507
resolver
ensembl
ENSRNOG00055012100
resolver
ensembl
ENSRNOG00060008650
resolver
ensembl
ENSRNOG00065017329
resolver
ensp
ENSRNOP00000101868
resolver
ensp
ENSRNOP00000106097
resolver
ensp
ENSRNOP00055016571
resolver
ensp
ENSRNOP00060011129
resolver
ensp
ENSRNOP00065022858
resolver
enst
ENSRNOT00000145237
resolver
enst
ENSRNOT00000173146
resolver
enst
ENSRNOT00055020574
resolver
enst
ENSRNOT00060014466
resolver
enst
ENSRNOT00065028889
resolver
genesymbol
Twf1
resolver
genesymbol_syn
Ptk9
resolver
uniprot
A0ABK0L9P1
resolver
uniprot_entry
A0ABK0L9P1_RAT
resolver
uniprot_entry
TWF1_RAT
resolver
amino_acid_sequence
MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVVGSCSPPSDSWEQDYDPFVLPLLEDKQPCYVLFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDEVFGTVKEDVSLHGYRKYLLSQSSPAPLTAAEEELRQIKISEVQTDVSVDTKHQTLQGVAFPISRDAFQALEKLSKRQLNYVQLEIDIKNETIILANTENTELKDLPKRIPKDSARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSPLLDIVERQLQMDVIRKIEIDNGDELTADFLYDEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAEAEATTD
uniprot
proteins
function
FUNCTION: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
40090
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on serine and threonine residues. {ECO:0000250}.
uniprot
proteins
protein_family
Actin-binding proteins ADF family
uniprot
proteins
protein_family
Twinfilin subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
350
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts (By similarity). {ECO:0000250}.
uniprot
proteins