Gkap1
entrez
56278
canonical
uniprot
Q9JMB0
canonical
ensembl
ENSMUSG00000021552
resolver
ensp
ENSMUSP00000089169
resolver
ensp
ENSMUSP00000187992
resolver
ensp
ENSMUSP00000187995
resolver
ensp
ENSMUSP00000188000
resolver
enst
ENSMUST00000091579
resolver
genesymbol
Gkap1
resolver
genesymbol_syn
Gkap42
resolver
uniprot
Q9CUD8
resolver
uniprot_entry
GKAP1_MOUSE
resolver
uniprot_sec
Q9CUD8
resolver
amino_acid_sequence
MASAVLSSVLTTASRFALLQVDSGSGSDSEPGKGKGRSNGKSQTLGNKATSNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHSICNVQHELSSPNPAQKESREENWQEWRQKDEQLTSEMFEADLEKALLLSKLEYEEHKQDYENAETASTQTKGINKKDKRKNHQGKDKPVTVSLKDFQCEDHISKKAEESNSAQTLSHDGGFFNRLEDDVHKILIREKRREQLTEHNGTDNSPAPEHNQEVGLKDGRIERLKLELERKDAEIQKLKAVITQWEAKYKEVKARNGQLLKMLQEGEMKDKAEILLQVDESQSIKNELTVQVSSLHAALEQERSKVKVLQAELAKYQGGRKGKRNFEPDHCR
uniprot
proteins
function
FUNCTION: Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation. {ECO:0000269|PubMed:25586176}.
uniprot
proteins
mass_dalton
41763
uniprot
proteins
mutagenesis
MUTAGEN 86; /note="S->A: Does not affect phosphorylation by PKG."; /evidence="ECO:0000269|PubMed:10671526"; MUTAGEN 106; /note="S->A: Affects phosphorylation by PKG."; /evidence="ECO:0000269|PubMed:10671526"; MUTAGEN 178; /note="T->A: Does not affect phosphorylation by PKG."; /evidence="ECO:0000269|PubMed:10671526
uniprot
proteins
protein_family
GKAP1 family
uniprot
proteins
pubmed
10671526
uniprot
proteins
pubmed
15028281
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25586176
uniprot
proteins
sequence_length
366
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:10671526}.
uniprot
proteins