SGCG
entrez
6445
canonical
uniprot
Q13326
canonical
ensembl
ENSG00000102683
resolver
ensp
ENSP00000218867
resolver
ensp
ENSP00000546423
resolver
ensp
ENSP00000546424
resolver
ensp
ENSP00000546425
resolver
ensp
ENSP00000612525
resolver
ensp
ENSP00000612526
resolver
ensp
ENSP00000612527
resolver
ensp
ENSP00000612530
resolver
enst
ENST00000218867
resolver
enst
ENST00000876364
resolver
enst
ENST00000876365
resolver
enst
ENST00000876366
resolver
enst
ENST00000942466
resolver
enst
ENST00000942467
resolver
enst
ENST00000942468
resolver
enst
ENST00000942471
resolver
genesymbol
SGCG
resolver
hgnc
HGNC:10809
resolver
uniprot
Q32M32
resolver
uniprot
Q5T9J6
resolver
uniprot_entry
SGCG_HUMAN
resolver
uniprot_sec
Q32M32
resolver
uniprot_sec
Q5T9J6
resolver
amino_acid_sequence
MVREQYTTATEGICIERPENQYVYKIGIYGWRKRCLYLFVLLLLIILVVNLALTIWILKVMWFSPAGMGHLCVTKDGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTQNVTVNARNSEGEVTGRLKVGPKMVEVQNQQFQINSNDGKPLFTVDEKEVVVGTDKLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHIQAHAGKIEALSQMDILFHSSDGMLVLDAETVCLPKLVQGTWGPSGSSQSLYEICVCPDGKLYLSVAGVSTTCQEHNHICL
uniprot
proteins
disease_involvement
DISEASE: Muscular dystrophy, limb-girdle, autosomal recessive 5 (LGMDR5) [MIM:253700]: An autosomal recessive degenerative myopathy characterized by rapidly progressive muscle wasting from early childhood with loss of independent ambulation around age 12 years, dystrophic pattern on muscle biopsy, absence of gamma-sarcoglycan and normal dystrophin immunostaining. {ECO:0000269|PubMed:10714584, ECO:0000269|PubMed:30345904, ECO:0000269|PubMed:8968757}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
uniprot
proteins
mass_dalton
32379
uniprot
proteins
protein_family
Sarcoglycan beta/delta/gamma/zeta family
uniprot
proteins
pubmed
10629222
uniprot
proteins
pubmed
10714584
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
30345904
uniprot
proteins
pubmed
7481775
uniprot
proteins
pubmed
8900232
uniprot
proteins
pubmed
8968757
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane, sarcolemma {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 38..58; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins