Pdp1
entrez
381511
canonical
uniprot
Q3UV70
canonical
ensembl
ENSMUSG00000049225
resolver
ensp
ENSMUSP00000092766
resolver
ensp
ENSMUSP00000103932
resolver
ensp
ENSMUSP00000103934
resolver
ensp
ENSMUSP00000103936
resolver
ensp
ENSMUSP00000103937
resolver
enst
ENSMUST00000095144
resolver
enst
ENSMUST00000108297
resolver
enst
ENSMUST00000108299
resolver
enst
ENSMUST00000108302
resolver
genesymbol
Pdp1
resolver
genesymbol_syn
Ppm2c
resolver
uniprot
A2AJP9
resolver
uniprot
A8Y5Q0
resolver
uniprot
A8Y5Q1
resolver
uniprot_entry
A2AJP9_MOUSE
resolver
uniprot_entry
A8Y5Q0_MOUSE
resolver
uniprot_entry
A8Y5Q1_MOUSE
resolver
uniprot_entry
PDP1_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Magnesium-dependent and calcium-stimulated (By similarity). PDP1 activity strongly depends on its Ca(2+)-dependent binding to the lipoyl domain of E2 subunit of component of the pyruvate dehydrogenase complex (By similarity). {ECO:0000250|UniProtKB:P35816, ECO:0000250|UniProtKB:Q9P0J1}.
uniprot
proteins
amino_acid_sequence
MPAPTQLFFPLVRNCELSRIYGTACYCHHKHLCCSPPYIPQNRLRYTPHPAYATFCRPRENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESADIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKNEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRAKMSSVFEDQNAATHLIRHAVGNNEFGAVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQEQ
uniprot
proteins
ec_number
3.1.3.43
uniprot
proteins
function
FUNCTION: Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA. {ECO:0000250|UniProtKB:P35816}.
uniprot
proteins
mass_dalton
61180
uniprot
proteins
protein_family
PP2C family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
538
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P35816}.
uniprot
proteins