CRLF2
entrez
64109
canonical
uniprot
Q9HC73
canonical
ensembl
ENSG00000205755
resolver
ensembl
ENSG00000292363
resolver
ensp
ENSP00000370979
resolver
ensp
ENSP00000383641
resolver
ensp
ENSP00000518623
resolver
ensp
ENSP00000642756
resolver
genesymbol
CRLF2
resolver
genesymbol_syn
CRL2
resolver
genesymbol_syn
ILXR
resolver
genesymbol_syn
TSLPR
resolver
hgnc
HGNC:14281
resolver
uniprot
J3QKD1
resolver
uniprot
Q5G7M1
resolver
uniprot
Q9H5R3
resolver
uniprot_entry
CRLF2_HUMAN
resolver
uniprot_sec
J3QKD1
resolver
uniprot_sec
Q5G7M1
resolver
uniprot_sec
Q9H5R3
resolver
amino_acid_sequence
MGRLVLLWGAAVFLLGGWMALGQGGAAEGVQIQIIYFNLETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRVKKFLIPSVPDPKSIFPGLFEIHQGNFQEWITDTQNVAHLHKMAGAEQESGPEEPLVVQLAKTEAESPRMLDPQTEEKEASGGSLQLPHQPLQGGDVVTIGGFTFVMNDRSYVAL
uniprot
proteins
function
FUNCTION: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. {ECO:0000250, ECO:0000269|PubMed:11418668}.
uniprot
proteins
mass_dalton
42013
uniprot
proteins
protein_family
Type 5 subfamily
uniprot
proteins
protein_family
Type I cytokine receptor family
uniprot
proteins
pubmed
11237741
uniprot
proteins
pubmed
11418668
uniprot
proteins
pubmed
11474172
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15772651
uniprot
proteins
sequence_length
371
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins