H2BK1
entrez
114483833
canonical
uniprot
A0A2R8Y619
canonical
ensembl
ENSG00000285480
resolver
ensp
ENSP00000495192
resolver
enst
ENST00000644661
resolver
genesymbol
H2BK1
resolver
genesymbol_syn
H2BE1
resolver
hgnc
HGNC:53833
resolver
uniprot_entry
H2BK1_HUMAN
resolver
amino_acid_sequence
MSAEYGQRQQPGGRGGRSSGNKKSKKRCRRKESYSMYIYKVLKQVHPDIGISAKAMSIMNSFVNDVFEQLACEAARLAQYSGRTTLTSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
uniprot
proteins
function
FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. {ECO:0000250|UniProtKB:P70696}.
uniprot
proteins
mass_dalton
13491
uniprot
proteins
protein_family
Histone H2B family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
31537640
uniprot
proteins
sequence_length
122
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Chromosome {ECO:0000250|UniProtKB:P70696}. Nucleus {ECO:0000250|UniProtKB:P70696}.
uniprot
proteins