RGP1
entrez
9827
canonical
uniprot
Q92546
canonical
ensembl
ENSG00000107185
resolver
ensp
ENSP00000367318
resolver
ensp
ENSP00000551035
resolver
ensp
ENSP00000601368
resolver
enst
ENST00000378078
resolver
enst
ENST00000880976
resolver
enst
ENST00000931309
resolver
genesymbol
RGP1
resolver
genesymbol_syn
KIAA0258
resolver
hgnc
HGNC:21965
resolver
uniprot
A8K0K1
resolver
uniprot
Q5TCV5
resolver
uniprot_entry
A8K0K1_HUMAN
resolver
uniprot_entry
RGP1_HUMAN
resolver
uniprot_sec
Q5TCV5
resolver
amino_acid_sequence
MIEVVAELSRGPVFLAGEALECVVTVTNPLPPTATSASSEALAWASAQIHCQFHASESRVALPPPDSSQPDVQPDSQTVFLPHRGERGQCILSTPPKILFCDLRLDPGESKSYSYSEVLPIEGPPSFRGQSVKYVYKLTIGCQRVNSPITLLRVPLRVLVLTGLQDVRFPQDEAVAPSSPFLEEDEGGKKDSWLAELAGERLMAATSCRSLHLYNISDGRGKVGTFGIFKSVYRLGEDVVGTLNLGEGTVACLQFSVSLQTEERVQPEYQRRRGAGGVPSVSHVTHARHQESCLHTTRTSFSLPIPLSSTPGFCTAIVSLKWRLHFEFVTSREPGLVLLPPVEQPEPTTWTGPEQVPVDTFSWDLPIKVLPTSPTLASYAAPGPSTSTITI
uniprot
proteins
function
FUNCTION: The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. {ECO:0000269|PubMed:23091056}.
uniprot
proteins
mass_dalton
42455
uniprot
proteins
protein_family
RGP1 family
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23091056
uniprot
proteins
pubmed
9039502
uniprot
proteins
sequence_length
391
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:23091056}. Membrane {ECO:0000269|PubMed:23091056}.
uniprot
proteins