CYB5R4
entrez
51167
canonical
uniprot
Q7L1T6
canonical
ensembl
ENSG00000065615
resolver
ensp
ENSP00000358695
resolver
enst
ENST00000369681
resolver
genesymbol
CYB5R4
resolver
genesymbol_syn
NCB5OR
resolver
hgnc
HGNC:20147
resolver
uniprot
B1AEM2
resolver
uniprot
Q5TGI9
resolver
uniprot
Q9NUE4
resolver
uniprot
Q9UHI9
resolver
uniprot_entry
NB5R4_HUMAN
resolver
uniprot_sec
B1AEM2
resolver
uniprot_sec
Q5TGI9
resolver
uniprot_sec
Q9NUE4
resolver
uniprot_sec
Q9UHI9
resolver
amino_acid_sequence
MLNVPSQSFPAPRSQQRVASGGRSKVPLKQGRSLMDWIRLTKSGKDLTGLKGRLIEVTEEELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGSDGTELFDQVHRWVNYESMLKECLVGRMAIKPAVLKDYREEEKKVLNGMLPKSQVTDTLAKEGPSYPSYDWFQTDSLVTIAIYTKQKDINLDSIIVDHQNDSFRAETIIKDCLYLIHIGLSHEVQEDFSVRVVESVGKIEIVLQKKENTSWDFLGHPLKNHNSLIPRKDTGLYYRKCQLISKEDVTHDTRLFCLMLPPSTHLQVPIGQHVYLKLPITGTEIVKPYTPVSGSLLSEFKEPVLPNNKYIYFLIKIYPTGLFTPELDRLQIGDFVSVSSPEGNFKISKFQELEDLFLLAAGTGFTPMVKILNYALTDIPSLRKVKLMFFNKTEDDIIWRSQLEKLAFKDKRLDVEFVLSAPISEWNGKQGHISPALLSEFLKRNLDKSKVLVCICGPVPFTEQGVRLLHDLNFSKNEIHSFTA
uniprot
proteins
ec_number
1.6.2.2
uniprot
proteins
function
FUNCTION: NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.
uniprot
proteins
mass_dalton
59474
uniprot
proteins
protein_family
Flavoprotein pyridine nucleotide cytochrome reductase family
uniprot
proteins
pubmed
10611283
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15131110
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15504981
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
20630863
uniprot
proteins
pubmed
22814378
uniprot
proteins
sequence_length
521
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:10611283, ECO:0000269|PubMed:15131110}. Note=Soluble protein.
uniprot
proteins