GYG2
entrez
8908
canonical
uniprot
O15488
canonical
ensembl
ENSG00000056998
resolver
ensp
ENSP00000370555
resolver
ensp
ENSP00000381786
resolver
ensp
ENSP00000487294
resolver
ensp
ENSP00000538697
resolver
ensp
ENSP00000538698
resolver
ensp
ENSP00000538703
resolver
ensp
ENSP00000538705
resolver
ensp
ENSP00000592840
resolver
ensp
ENSP00000592842
resolver
ensp
ENSP00000628400
resolver
ensp
ENSP00000628404
resolver
genesymbol
GYG2
resolver
hgnc
HGNC:4700
resolver
uniprot
A8K8Y1
resolver
uniprot
B3KUV6
resolver
uniprot
B7WNN6
resolver
uniprot
O15485
resolver
uniprot
O15486
resolver
uniprot
O15487
resolver
uniprot
O15489
resolver
uniprot
O15490
resolver
uniprot
Q1ZYL7
resolver
uniprot_entry
A8K8Y1_HUMAN
resolver
uniprot_entry
B3KUV6_HUMAN
resolver
uniprot_entry
GLYG2_HUMAN
resolver
uniprot_entry
Q1ZYL7_HUMAN
resolver
uniprot_sec
B7WNN6
resolver
uniprot_sec
O15485
resolver
uniprot_sec
O15486
resolver
uniprot_sec
O15487
resolver
uniprot_sec
O15489
resolver
uniprot_sec
O15490
resolver
amino_acid_sequence
MSETEFHHGAQAGLELLRSSNSPTSASQSAGMTVTDQAFVTLATNDIYCQGALVLGQSLRRHRLTRKLVVLITPQVSSLLRVILSKVFDEVIEVNLIDSADYIHLAFLKRPELGLTLTKLHCWTLTHYSKCVFLDADTLVLSNVDELFDRGEFSAAPDPGWPDCFNSGVFVFQPSLHTHKLLLQHAMEHGSFDGADQGLLNSFFRNWSTTDIHKHLPFIYNLSSNTMYTYSPAFKQFGSSAKVVHFLGSMKPWNYKYNPQSGSVLEQGSASSSQHQAAFLHLWWTVYQNNVLPLYKSVQAGEARASPGHTLCHSDVGGPCADSASGVGEPCENSTPSAGVPCANSPLGSNQPAQGLPEPTQIVDETLSLPEGRRSEDMIACPETETPAVITCDPLSQPSPQPADFTETETILQPANKVESVSSEETFEPSQELPAEALRDPSLQDALEVDLAVSVSQISIEEKVKELSPEEERRKWEEGRIDYMGKDAFARIQEKLDRFLQ
uniprot
proteins
ec_number
2.4.1.186
uniprot
proteins
function
FUNCTION: Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase. {ECO:0000269|PubMed:9346895, ECO:0000269|PubMed:9857012}.
uniprot
proteins
mass_dalton
55184
uniprot
proteins
mutagenesis
MUTAGEN 228; /note="Y->F: Loss of autoglucosylation."; /evidence="ECO:0000269|PubMed:9857012"; MUTAGEN 230; /note="Y->F: No loss of activity."; /evidence="ECO:0000269|PubMed:9857012
uniprot
proteins
pathway_participation
PATHWAY: Glycan biosynthesis; glycogen biosynthesis. {ECO:0000269|PubMed:9346895, ECO:0000269|PubMed:9857012}.
uniprot
proteins
post_translational_modification
PTM: Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-228. {ECO:0000269|PubMed:9857012}.
uniprot
proteins
protein_family
Glycogenin subfamily
uniprot
proteins
protein_family
Glycosyltransferase 8 family
uniprot
proteins
pubmed
10721716
uniprot
proteins
pubmed
11840567
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
21248752
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9346895
uniprot
proteins
pubmed
9857012
uniprot
proteins
sequence_length
501
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P13280}. Nucleus {ECO:0000250|UniProtKB:P13280}. Note=Localizes to glycogen granules (glycosomes) in the cytoplasm (By similarity). Cytosolic localization is dependent on the actin cytoskeleton (By similarity). {ECO:0000250|UniProtKB:C4R941, ECO:0000250|UniProtKB:P13280}.
uniprot
proteins