PRG3
entrez
10394
canonical
uniprot
Q9Y2Y8
canonical
ensembl
ENSG00000156575
resolver
ensp
ENSP00000287143
resolver
enst
ENST00000287143
resolver
genesymbol
PRG3
resolver
genesymbol_syn
MBPH
resolver
hgnc
HGNC:9363
resolver
uniprot_entry
PRG3_HUMAN
resolver
amino_acid_sequence
MQCLLLLPFLLLGTVSALHLENDAPHLESLETQADLGQDLDSSKEQERDLALTEEVIQAEGEEVKASACQDNFEDEEAMESDPAALDKDFQCPREEDIVEVQGSPRCKICRYLLVRTPKTFAEAQNVCSRCYGGNLVSIHDFNFNYRIQCCTSTVNQAQVWIGGNLRGWFLWKRFCWTDGSHWNFAYWSPGQPGNGQGSCVALCTKGGYWRRAQCDKQLPFVCSF
uniprot
proteins
function
FUNCTION: Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils. {ECO:0000269|PubMed:10318872}.
uniprot
proteins
mass_dalton
25406
uniprot
proteins
pubmed
10318872
uniprot
proteins
pubmed
11170744
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
sequence_length
225
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic granule {ECO:0000269|PubMed:10318872}. Note=Localized to the eosinophil secondary granule.
uniprot
proteins