Phlda2
entrez
22113
canonical
uniprot
O08969
canonical
ensembl
ENSMUSG00000010760
resolver
ensp
ENSMUSP00000010904
resolver
enst
ENSMUST00000010904
resolver
genesymbol
Phlda2
resolver
genesymbol_syn
Ipl
resolver
genesymbol_syn
Tssc3
resolver
uniprot_entry
PHLA2_MOUSE
resolver
amino_acid_sequence
MASKIVMSSKTVKTSDEILCEGELEKRSDSLFQVWKKKRCVLTADRLRLFSGKTSPAKELFFHSILKVDCVEHTSKYVYFTIVTNYYKEIDFRCTVESCWNAAITMALIDFQNRRALQDFPRYRYQRSESEMPSEPGEQSALGP
uniprot
proteins
function
FUNCTION: Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids. {ECO:0000269|PubMed:12032310}.
uniprot
proteins
mass_dalton
16727
uniprot
proteins
mutagenesis
MUTAGEN 27; /note="R->L: Impairs the ability to rescue growth in cdc25ts mutant yeasts."; /evidence="ECO:0000269|PubMed:12374806"; MUTAGEN 38; /note="K->A: Impairs the ability to rescue growth in cdc25ts mutant yeasts."; /evidence="ECO:0000269|PubMed:12374806"; MUTAGEN 39; /note="R->A: Impairs the ability to rescue growth in cdc25ts mutant yeasts."; /evidence="ECO:0000269|PubMed:12374806
uniprot
proteins
protein_family
PHLDA2 family
uniprot
proteins
pubmed
10594239
uniprot
proteins
pubmed
12032310
uniprot
proteins
pubmed
12374806
uniprot
proteins
pubmed
15327781
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
9328465
uniprot
proteins
sequence_length
144
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12374806}. Membrane {ECO:0000269|PubMed:12374806}; Peripheral membrane protein {ECO:0000269|PubMed:12374806}.
uniprot
proteins