TBC1D22A
entrez
25771
canonical
uniprot
Q8WUA7
canonical
ensembl
ENSG00000054611
resolver
ensp
ENSP00000336724
resolver
ensp
ENSP00000347932
resolver
ensp
ENSP00000370383
resolver
ensp
ENSP00000384036
resolver
ensp
ENSP00000385634
resolver
ensp
ENSP00000529850
resolver
ensp
ENSP00000647364
resolver
ensp
ENSP00000698714
resolver
ensp
ENSP00000782958
resolver
enst
ENST00000380995
resolver
enst
ENST00000407381
resolver
genesymbol
TBC1D22A
resolver
genesymbol_syn
C22orf4
resolver
hgnc
HGNC:1309
resolver
uniprot
A0A0A0MRY0
resolver
uniprot
B0QYI1
resolver
uniprot
B0QYI2
resolver
uniprot
B0QYI3
resolver
uniprot
B9A6M3
resolver
uniprot
Q5TE47
resolver
uniprot
Q6ZUH2
resolver
uniprot
Q92680
resolver
uniprot
Q9BVD6
resolver
uniprot
Q9UGG0
resolver
uniprot
Q9UGT2
resolver
uniprot
Q9UGU6
resolver
uniprot
Q9UH25
resolver
uniprot
Q9Y4W5
resolver
uniprot_entry
A0A0A0MRY0_HUMAN
resolver
uniprot_entry
B0QYI1_HUMAN
resolver
uniprot_entry
TB22A_HUMAN
resolver
uniprot_sec
B0QYI2
resolver
uniprot_sec
B0QYI3
resolver
uniprot_sec
B9A6M3
resolver
uniprot_sec
Q5TE47
resolver
uniprot_sec
Q6ZUH2
resolver
uniprot_sec
Q92680
resolver
uniprot_sec
Q9BVD6
resolver
uniprot_sec
Q9UGG0
resolver
uniprot_sec
Q9UGT2
resolver
uniprot_sec
Q9UGU6
resolver
uniprot_sec
Q9UH25
resolver
uniprot_sec
Q9Y4W5
resolver
amino_acid_sequence
MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK
uniprot
proteins
function
FUNCTION: May act as a GTPase-activating protein for Rab family protein(s). {ECO:0000250}.
uniprot
proteins
mass_dalton
59121
uniprot
proteins
mutagenesis
MUTAGEN 90..92; /note="NSE->AAA: No effect on ACBD3-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 92..93; /note="EV->AA: No effect on interaction with ACBD3, nor with 14-3-3 proteins."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 93..96; /note="VVME->AAAA: Decreased ACBD3-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 96..97; /note="ET->AA: No effect on ACBD3-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 99..100; /note="NR->AA: No effect on ACBD3-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 101..102; /note="VL->AA: Drastically decreased ACBD3-binding. No effect on binding to 14-3-3 protein."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 103..105; /note="RNH->AAA: No effect on ACBD3-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 132; /note="S->A: No effect on 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 149..150; /note="TS->EE: Decreased 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 165..167; /note="SQS->AQA: Complete loss of 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 165..167; /note="SQS->EQE: Complete loss of 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 165; /note="S->A: No effect on interaction with ACBD3. Decreased 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 165; /note="S->E: Complete loss of 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 167; /note="S->E: Complete loss of 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552"; MUTAGEN 320; /note="Q->A: Decreased 14-3-3 protein-binding."; /evidence="ECO:0000269|PubMed:23572552
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
12529303
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18186464
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19077034
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23572552
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
517
uniprot
proteins