Rnf166
entrez
365022
canonical
uniprot
Q6J1I7
canonical
ensembl
ENSRNOG00000013777
resolver
ensembl
ENSRNOG00055020449
resolver
ensembl
ENSRNOG00060016424
resolver
ensembl
ENSRNOG00065006788
resolver
ensp
ENSRNOP00000018591
resolver
ensp
ENSRNOP00055028325
resolver
ensp
ENSRNOP00060022652
resolver
ensp
ENSRNOP00065007779
resolver
enst
ENSRNOT00000018591
resolver
enst
ENSRNOT00055034914
resolver
enst
ENSRNOT00060028133
resolver
enst
ENSRNOT00065010558
resolver
genesymbol
Rnf166
resolver
uniprot_entry
RN166_RAT
resolver
amino_acid_sequence
MAMFRSLVASAQQRQPPAGPAGGDSGLEAQFSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCNKKVTLAKMRAHISSCLKVQEQMANCPKFVPVVPTSQPIPSNIPNRSTFACPYCGARNLDQQELVKHCVESHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Also plays a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication. {ECO:0000250|UniProtKB:Q96A37}.
uniprot
proteins
mass_dalton
26064
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:Q96A37}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
237
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96A37}.
uniprot
proteins