Nfil3
entrez
114519
canonical
uniprot
Q6IMZ0
canonical
ensembl
ENSRNOG00000011668
resolver
ensembl
ENSRNOG00055015605
resolver
ensembl
ENSRNOG00060017820
resolver
ensembl
ENSRNOG00065010003
resolver
ensp
ENSRNOP00000015525
resolver
ensp
ENSRNOP00000089110
resolver
ensp
ENSRNOP00000090522
resolver
ensp
ENSRNOP00000093138
resolver
ensp
ENSRNOP00000099686
resolver
ensp
ENSRNOP00000104717
resolver
ensp
ENSRNOP00055021572
resolver
ensp
ENSRNOP00055021575
resolver
ensp
ENSRNOP00055021578
resolver
ensp
ENSRNOP00055021581
resolver
ensp
ENSRNOP00060024654
resolver
ensp
ENSRNOP00060024672
resolver
ensp
ENSRNOP00060024693
resolver
ensp
ENSRNOP00060024694
resolver
ensp
ENSRNOP00065012180
resolver
ensp
ENSRNOP00065012181
resolver
ensp
ENSRNOP00065012186
resolver
ensp
ENSRNOP00065012187
resolver
enst
ENSRNOT00000015525
resolver
enst
ENSRNOT00000096237
resolver
enst
ENSRNOT00000096697
resolver
enst
ENSRNOT00000112357
resolver
enst
ENSRNOT00000140464
resolver
enst
ENSRNOT00000144491
resolver
enst
ENSRNOT00055026598
resolver
enst
ENSRNOT00055026602
resolver
enst
ENSRNOT00055026606
resolver
enst
ENSRNOT00055026610
resolver
enst
ENSRNOT00060030501
resolver
enst
ENSRNOT00060030518
resolver
enst
ENSRNOT00060030539
resolver
enst
ENSRNOT00060030540
resolver
enst
ENSRNOT00065016083
resolver
enst
ENSRNOT00065016084
resolver
enst
ENSRNOT00065016087
resolver
enst
ENSRNOT00065016090
resolver
genesymbol
Nfil3
resolver
uniprot
Q923M2
resolver
uniprot_entry
NFIL3_RAT
resolver
uniprot_sec
Q923M2
resolver
amino_acid_sequence
MQLRKMQAIKKEPASLDPTGSSDKMLLLNSALAEVAEDLASGEDLLLNEGSMGKNKSSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSTVYAQEIQKLSNSTAVYFQDYQTSKAAVSSYVDEHEPAMVAGSCISVIKHSPQSSLSDVSEVSSVEHTQESPAQGGCRSPENKFPVIKQEPVELESFARESREERGAYSASIYQSYMGSSFSTYSHSPPLLQVHGSTSNSPRTSEADEGVVGKSSDGEDEQQVPKGPIHSPVELQRVHATVVKVPEVNPSALPHKLRIKAKAMQVKVEALDSEFEGMQKLSSPADALAKRHFDLEKHGASGTAHSSLPPFSVQVTNIQDWSLRSEHWHHKELGGKTQGTFKTGVVEVKDSGYKVSEAENLYLKQGVANLSAEVVSLKRFIATQPISASDSR
uniprot
proteins
function
FUNCTION: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death (By similarity). Represses the transcription of CYP2A5 (By similarity). Positively regulates the expression and activity of CES2 by antagonizing the repressive action of NR1D1 on CES2 (By similarity). Required for the development of natural killer cell precursors (By similarity). {ECO:0000250|UniProtKB:O08750, ECO:0000250|UniProtKB:Q16649}.
uniprot
proteins
mass_dalton
50781
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
protein_family
NFIL3 subfamily
uniprot
proteins
pubmed
11262393
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
462
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
uniprot
proteins