PLPPR4
entrez
9890
canonical
uniprot
Q7Z2D5
canonical
ensembl
ENSG00000117600
resolver
ensp
ENSP00000359204
resolver
ensp
ENSP00000394913
resolver
enst
ENST00000457765
resolver
genesymbol
PLPPR4
resolver
genesymbol_syn
KIAA0455
resolver
genesymbol_syn
LPPR4
resolver
genesymbol_syn
PHP1
resolver
genesymbol_syn
PRG1
resolver
hgnc
HGNC:23496
resolver
uniprot
A0AAA9X798
resolver
uniprot
E7EPS1
resolver
uniprot
O75043
resolver
uniprot
Q5T9R9
resolver
uniprot
Q86XQ5
resolver
uniprot
Q8N3F1
resolver
uniprot
Q96MP0
resolver
uniprot_entry
A0AAA9X798_HUMAN
resolver
uniprot_entry
PLPR4_HUMAN
resolver
uniprot_sec
E7EPS1
resolver
uniprot_sec
O75043
resolver
uniprot_sec
Q5T9R9
resolver
uniprot_sec
Q86XQ5
resolver
uniprot_sec
Q8N3F1
resolver
uniprot_sec
Q96MP0
resolver
amino_acid_sequence
MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMRSSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
uniprot
proteins
function
FUNCTION: Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA)-mediated signaling pathways. Binds lysophosphatidic acid (LPA) and mediates its internalization into cells. Could act as receptor or a transporter of this lipid at the post-synaptic membrane (By similarity). Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid-induced axon collapse (By similarity). {ECO:0000250|UniProtKB:Q7TMB7, ECO:0000250|UniProtKB:Q7TME0}.
uniprot
proteins
mass_dalton
82983
uniprot
proteins
post_translational_modification
PTM: O-glycosylated. Probably at Ser-346. {ECO:0000250|UniProtKB:Q7TME0}.
uniprot
proteins
protein_family
PA-phosphatase related phosphoesterase family
uniprot
proteins
pubmed
12730698
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15280885
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
26671989
uniprot
proteins
pubmed
36977636
uniprot
proteins
pubmed
9455484
uniprot
proteins
sequence_length
763
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic density membrane {ECO:0000269|PubMed:26671989}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 67..87; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 119..139; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 178..198; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 247..267; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 276..296; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins