RASA4
entrez
10156
canonical
uniprot
O43374
canonical
ensembl
ENSG00000105808
resolver
ensp
ENSP00000262940
resolver
ensp
ENSP00000412876
resolver
ensp
ENSP00000417395
resolver
ensp
ENSP00000420352
resolver
ensp
ENSP00000673643
resolver
ensp
ENSP00000673645
resolver
ensp
ENSP00000702066
resolver
ensp
ENSP00000702067
resolver
enst
ENST00000461209
resolver
enst
ENST00000462172
resolver
genesymbol
RASA4
resolver
genesymbol_syn
CAPRI
resolver
genesymbol_syn
GAPL
resolver
genesymbol_syn
KIAA0538
resolver
hgnc
HGNC:23181
resolver
uniprot
E7ERK1
resolver
uniprot
O60286
resolver
uniprot
Q14CQ4
resolver
uniprot
Q86UW3
resolver
uniprot
Q96QU0
resolver
uniprot_entry
E7ERK1_HUMAN
resolver
uniprot_entry
RASL2_HUMAN
resolver
uniprot_sec
O60286
resolver
uniprot_sec
Q14CQ4
resolver
uniprot_sec
Q86UW3
resolver
uniprot_sec
Q96QU0
resolver
amino_acid_sequence
MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAMLWERHRELSGGAEAGTVPTSPGKVPEDSLARLLRVLQDLREAHSSSPAGSPPSEPNCLLELQT
uniprot
proteins
function
FUNCTION: Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. {ECO:0000269|PubMed:11448776}.
uniprot
proteins
mass_dalton
90458
uniprot
proteins
pubmed
11448776
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9628581
uniprot
proteins
sequence_length
803
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:11448776}. Cell membrane {ECO:0000269|PubMed:11448776}; Peripheral membrane protein {ECO:0000269|PubMed:11448776}. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane.
uniprot
proteins