Nck2
entrez
17974
canonical
uniprot
O55033
canonical
ensembl
ENSMUSG00000066877
resolver
ensp
ENSMUSP00000083611
resolver
ensp
ENSMUSP00000304597
resolver
enst
ENSMUST00000086421
resolver
genesymbol
Nck2
resolver
genesymbol_syn
Grb4
resolver
uniprot
Q8BQ28
resolver
uniprot_entry
NCK2_MOUSE
resolver
uniprot_entry
Q8BQ28_MOUSE
resolver
amino_acid_sequence
MTEEVIVIAKWDYTAQQDQELDIRKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKPSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSFNGQIGWFPSNYVLEEADEAAAEAPSFLSLRRGTALSNGQGARVLHVVQTLYPFSSVTEEELSFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGPALHPAHTPQISYTGPSASGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGRNKHFKVQLVDSVYCIGQRRFHSMDELVEHYKKAPIFTSEHGEKLYLVRALQ
uniprot
proteins
function
FUNCTION: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. {ECO:0000250|UniProtKB:O43639}.
uniprot
proteins
mass_dalton
42879
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17947660
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
380
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O43639}. Endoplasmic reticulum {ECO:0000250|UniProtKB:O43639}.
uniprot
proteins