Tfap2d
entrez
226896
canonical
uniprot
Q91ZK0
canonical
ensembl
ENSMUSG00000042596
resolver
ensp
ENSMUSP00000037699
resolver
enst
ENSMUST00000037294
resolver
genesymbol
Tfap2d
resolver
genesymbol_syn
Tcfap2d
resolver
uniprot
A7MCU6
resolver
uniprot_entry
AP2D_MOUSE
resolver
uniprot_sec
A7MCU6
resolver
amino_acid_sequence
MSTTFPGLVHDAEIRHDGSNSYRLMQLGCLESVANSTVAYSSSSPLTYSTTGTEFASPYFSTNHQYTPLHHQSFHYEFQHSHPAVTPDAYSLNSLHHSQQYYQQIHHGEPTDFINLHNARALKSSCLDEQRRELGCLDAYRRHDLSLMSHGSQYGMHPDQRLLPGPSLGLAAAGADDLQGSVEAQCGIVLNGQGGVIRRGGTCVVNPTDLFCSVPGRLSLLSSTSKYKVTIAEVKRRLSPPECLNASLLGGILRRAKSKNGGRCLREKLDRLGLNLPAGRRKAANVTLLTSLVEGEALHLARDFGYTCETEFPAKAVGEHLARQHMEQKEQTARKKMILATKQICKEFQDLLSQDRSPLGSSRPTPILDLDIQRHLTHFSLITHGFGTPAICAALSTFQTVLSEMLNYLEKHTTHKNGGAADSGQGHANSEKAPLRKASEAAVKEGKTEKTD
uniprot
proteins
function
FUNCTION: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. {ECO:0000269|PubMed:11522791, ECO:0000305}.
uniprot
proteins
mass_dalton
49548
uniprot
proteins
protein_family
AP-2 family
uniprot
proteins
pubmed
11522791
uniprot
proteins
pubmed
12711551
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
452
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins