PRB3
entrez
5544
canonical
uniprot
Q04118
canonical
ensembl
ENSG00000197870
resolver
ensembl
ENSG00000275624
resolver
ensp
ENSP00000442626
resolver
ensp
ENSP00000481020
resolver
ensp
ENSP00000488472
resolver
enst
ENST00000538488
resolver
enst
ENST00000617491
resolver
enst
ENST00000632935
resolver
genesymbol
PRB3
resolver
hgnc
HGNC:9339
resolver
uniprot
A0A0G2JNB4
resolver
uniprot
F5H7C1
resolver
uniprot
Q15188
resolver
uniprot
Q4VAY3
resolver
uniprot
Q4VAY4
resolver
uniprot
Q7M4M9
resolver
uniprot
Q9UCT9
resolver
uniprot_entry
A0A0G2JNB4_HUMAN
resolver
uniprot_entry
PRB3_HUMAN
resolver
uniprot_sec
F5H7C1
resolver
uniprot_sec
Q15188
resolver
uniprot_sec
Q4VAY3
resolver
uniprot_sec
Q4VAY4
resolver
uniprot_sec
Q7M4M9
resolver
uniprot_sec
Q9UCT9
resolver
amino_acid_sequence
MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNKPQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ
uniprot
proteins
function
FUNCTION: Acts as a receptor for the Gram-negative bacterium F.nucleatum. {ECO:0000269|PubMed:1894623}.
uniprot
proteins
mass_dalton
35123
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated; contains about 50% carbohydrate. This is composed of highly fucosylated N-linked saccharides, the major structure is a biantennary asialosaccharide containing 2 fucose residues on one antenna and an unsubstituted terminal lactosamine sequence on the other. The Gram-negative bacterium F.nucleatum binds to carbohydrates containing unsubstituted GalBeta1,4GlcNAc residues. N-glycosylation on Asn-87 is prevalent in head and neck cancer patients. {ECO:0000269|PubMed:1894623, ECO:0000269|PubMed:20879038}.; PTM: Proteolytically cleaved at the tripeptide Xaa-Pro-Gln, where Xaa in the P(3) position is mostly lysine. The endoprotease may be of microbial origin. Besides on the N-terminal of mature PRB3, pyroglutamate formation found on at least Gln-67, Gln-88, Gln-256 and Gln-337. {ECO:0000269|PubMed:18463091}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
18463091
uniprot
proteins
pubmed
1894623
uniprot
proteins
pubmed
20879038
uniprot
proteins
pubmed
2171329
uniprot
proteins
pubmed
2851479
uniprot
proteins
sequence_length
351
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins