Adcyap1r1
entrez
11517
canonical
uniprot
P70205
canonical
ensembl
ENSMUSG00000029778
resolver
ensp
ENSMUSP00000063784
resolver
ensp
ENSMUSP00000066902
resolver
ensp
ENSMUSP00000126994
resolver
ensp
ENSMUSP00000127319
resolver
ensp
ENSMUSP00000129614
resolver
ensp
ENSMUSP00000130923
resolver
ensp
ENSMUSP00000287843
resolver
enst
ENSMUST00000070736
resolver
enst
ENSMUST00000070756
resolver
enst
ENSMUST00000165786
resolver
enst
ENSMUST00000165857
resolver
enst
ENSMUST00000172084
resolver
genesymbol
Adcyap1r1
resolver
uniprot
E9Q3E8
resolver
uniprot
E9Q4B3
resolver
uniprot
E9Q968
resolver
uniprot
F8WGN8
resolver
uniprot
Q6NXJ9
resolver
uniprot_entry
E9Q3E8_MOUSE
resolver
uniprot_entry
E9Q4B3_MOUSE
resolver
uniprot_entry
E9Q968_MOUSE
resolver
uniprot_entry
F8WGN8_MOUSE
resolver
uniprot_entry
PACR_MOUSE
resolver
uniprot_entry
Q6NXJ9_MOUSE
resolver
amino_acid_sequence
MARTLQLSLTALLLLPMAIAMHSDCIFKKEQAMCLERIQRANDLMGLNESSPGCPGMWDNITCWKPAQIGEMVLVSCPEVFRIFNPDQVWMTETIGDSGFADSNSLEITDMGVVGRNCTEDGWSEPFPHYFDACGFDDYEPESGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSSHCFVSTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWAVLRLYFDDAGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIIILVQKLQSPDMGGNESSIYFSCVQKCYCKPQRAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFTMDFKHRHPSLASSGVNGGTQLSILSKSSSQLRMSSLPADNLAT
uniprot
proteins
function
FUNCTION: G protein-coupled receptor activated by the neuropeptide pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds both PACAP27 and PACAP38 bioactive peptides. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. {ECO:0000250|UniProtKB:P41586}.
uniprot
proteins
mass_dalton
56640
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8664310
uniprot
proteins
sequence_length
496
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P41586}.
uniprot
proteins
transmembrane_region
TRANSMEM 153..177; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:P41586"; TRANSMEM 188..208; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:P41586"; TRANSMEM 224..249; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:P41586"; TRANSMEM 268..290; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:P41586"; TRANSMEM 303..329; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:P41586"; TRANSMEM 348..402; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:P41586"; TRANSMEM 408..431; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:P41586
uniprot
proteins