KIF16B
entrez
55614
canonical
uniprot
Q96L93
canonical
ensembl
ENSG00000089177
resolver
ensp
ENSP00000347076
resolver
ensp
ENSP00000384164
resolver
ensp
ENSP00000489838
resolver
ensp
ENSP00000490639
resolver
ensp
ENSP00000566621
resolver
ensp
ENSP00000566622
resolver
ensp
ENSP00000587317
resolver
ensp
ENSP00000655550
resolver
ensp
ENSP00000655551
resolver
enst
ENST00000635823
resolver
enst
ENST00000636835
resolver
genesymbol
KIF16B
resolver
genesymbol_syn
C20orf23
resolver
genesymbol_syn
KIAA1590
resolver
genesymbol_syn
SNX23
resolver
hgnc
HGNC:15869
resolver
uniprot
A0A140VK74
resolver
uniprot
A0A1B0GTU3
resolver
uniprot
A0A1B0GVS8
resolver
uniprot
A6NKJ9
resolver
uniprot
A7E2A8
resolver
uniprot
B1AKG3
resolver
uniprot
B1AKT7
resolver
uniprot
C9JDN5
resolver
uniprot
C9JI52
resolver
uniprot
C9JSM8
resolver
uniprot
C9JWJ7
resolver
uniprot
Q2TBF5
resolver
uniprot
Q5HYC0
resolver
uniprot
Q5HYK1
resolver
uniprot
Q5JWW3
resolver
uniprot
Q5TFK5
resolver
uniprot
Q86VL9
resolver
uniprot
Q86YS5
resolver
uniprot
Q8IYU0
resolver
uniprot
Q9BQJ8
resolver
uniprot
Q9BQM0
resolver
uniprot
Q9BQM1
resolver
uniprot
Q9BQM5
resolver
uniprot
Q9H5U0
resolver
uniprot
Q9HCI2
resolver
uniprot
Q9NXN9
resolver
uniprot_entry
A0A140VK74_HUMAN
resolver
uniprot_entry
A0A1B0GTU3_HUMAN
resolver
uniprot_entry
A0A1B0GVS8_HUMAN
resolver
uniprot_entry
KI16B_HUMAN
resolver
uniprot_sec
A6NKJ9
resolver
uniprot_sec
A7E2A8
resolver
uniprot_sec
B1AKG3
resolver
uniprot_sec
B1AKT7
resolver
uniprot_sec
C9JDN5
resolver
uniprot_sec
C9JI52
resolver
uniprot_sec
C9JSM8
resolver
uniprot_sec
C9JWJ7
resolver
uniprot_sec
Q2TBF5
resolver
uniprot_sec
Q5HYC0
resolver
uniprot_sec
Q5HYK1
resolver
uniprot_sec
Q5JWW3
resolver
uniprot_sec
Q5TFK5
resolver
uniprot_sec
Q86VL9
resolver
uniprot_sec
Q86YS5
resolver
uniprot_sec
Q8IYU0
resolver
uniprot_sec
Q9BQJ8
resolver
uniprot_sec
Q9BQM0
resolver
uniprot_sec
Q9BQM1
resolver
uniprot_sec
Q9BQM5
resolver
uniprot_sec
Q9H5U0
resolver
uniprot_sec
Q9HCI2
resolver
uniprot_sec
Q9NXN9
resolver
amino_acid_sequence
MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDAHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVIAERRSHLEKYLRDFFSVMLQSATSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG
uniprot
proteins
function
FUNCTION: Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. {ECO:0000269|PubMed:15882625}.
uniprot
proteins
mass_dalton
152011
uniprot
proteins
mutagenesis
MUTAGEN 109; /note="S->A: Impairs plus end-directed microtubule-dependent motor activity, leading to impair EGFR recycling."; /evidence="ECO:0000269|PubMed:15882625"; MUTAGEN 1220; /note="R->A: Abolishes PtdIns(3)P-binding."; /evidence="ECO:0000269|PubMed:17641687"; MUTAGEN 1225; /note="R->A: Induces a 3-fold decrease in PtdIns(3)P-binding; when associated with A-1229 and A-1232."; /evidence="ECO:0000269|PubMed:17641687"; MUTAGEN 1229; /note="K->A: Induces a 3-fold decrease in PtdIns(3)P-binding; when associated with A-1225 and A-1232."; /evidence="ECO:0000269|PubMed:17641687"; MUTAGEN 1232; /note="K->A: Induces a 3-fold decrease in PtdIns(3)P-binding; when associated with A-1225 and A-1229."; /evidence="ECO:0000269|PubMed:17641687"; MUTAGEN 1248; /note="L->A: Induces a 7-fold decrease in PtdIns(3)P-binding and abolishes endosome localization. Induces a 25-fold decrease in PtdIns(3)P-binding; when associated with A-1249."; /evidence="ECO:0000269|PubMed:17641687"; MUTAGEN 1248; /note="L->V: Induces a 6-fold decrease in PtdIns(3)P-binding."; /evidence="ECO:0000269|PubMed:17641687"; MUTAGEN 1249; /note="F->A: Induces a 5-fold decrease in PtdIns(3)P-binding and abolishes endosome localization. Induces a 25-fold decrease in PtdIns(3)P-binding; when associated with A-1248."; /evidence="ECO:0000269|PubMed:17641687"; MUTAGEN 1260; /note="R->A: Induces a 30-fold decrease in PtdIns(3)P-binding."; /evidence="ECO:0000269|PubMed:17641687
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
10997877
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15882625
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17641687
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18445686
uniprot
proteins
pubmed
20923765
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
1317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}. Early endosome membrane {ECO:0000269|PubMed:15882625}. Cytoplasm {ECO:0000269|PubMed:18445686}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18445686}. Note=It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14. {ECO:0000269|PubMed:15882625}.
uniprot
proteins