POP7
entrez
10248
canonical
uniprot
O75817
canonical
ensembl
ENSG00000172336
resolver
ensp
ENSP00000304353
resolver
ensp
ENSP00000580850
resolver
ensp
ENSP00000604950
resolver
ensp
ENSP00000604951
resolver
ensp
ENSP00000604952
resolver
ensp
ENSP00000604953
resolver
ensp
ENSP00000604954
resolver
ensp
ENSP00000604955
resolver
ensp
ENSP00000604956
resolver
ensp
ENSP00000604957
resolver
ensp
ENSP00000604958
resolver
ensp
ENSP00000617268
resolver
enst
ENST00000303151
resolver
enst
ENST00000910791
resolver
enst
ENST00000934891
resolver
enst
ENST00000934892
resolver
enst
ENST00000934893
resolver
enst
ENST00000934894
resolver
enst
ENST00000934895
resolver
enst
ENST00000934896
resolver
enst
ENST00000934897
resolver
enst
ENST00000934898
resolver
enst
ENST00000934899
resolver
enst
ENST00000947209
resolver
genesymbol
POP7
resolver
genesymbol_syn
RPP20
resolver
hgnc
HGNC:19949
resolver
uniprot
A4D2E0
resolver
uniprot
Q9BV74
resolver
uniprot_entry
POP7_HUMAN
resolver
uniprot_sec
A4D2E0
resolver
uniprot_sec
Q9BV74
resolver
amino_acid_sequence
MAENREPRGAVEAELDPVEYTLRKRLPSRLPRRPNDIYVNMKTDFKAQLARCQKLLDGGARGQNACSEIYIHGLGLAINRAINIALQLQAGSFGSLQVAANTSTVELVDELEPETDTREPLTRIRNNSAIHIRVFRVTPK
uniprot
proteins
function
FUNCTION: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:30454648, PubMed:9630247). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465). {ECO:0000269|PubMed:28115465, ECO:0000269|PubMed:30454648, ECO:0000269|PubMed:9630247}.
uniprot
proteins
mass_dalton
15651
uniprot
proteins
mutagenesis
MUTAGEN 40; /note="N->Q: Strongly reduced interaction with RPP25."; /evidence="ECO:0000269|PubMed:20215441
uniprot
proteins
protein_family
Histone-like Alba family
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
14715275
uniprot
proteins
pubmed
15096576
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16723659
uniprot
proteins
pubmed
20215441
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
28115465
uniprot
proteins
pubmed
29625199
uniprot
proteins
pubmed
30454648
uniprot
proteins
pubmed
9630247
uniprot
proteins
sequence_length
140
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:14715275, ECO:0000269|PubMed:20215441}. Cytoplasm {ECO:0000269|PubMed:14715275}. Cytoplasmic granule {ECO:0000269|PubMed:14715275}. Note=Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules. {ECO:0000269|PubMed:14715275}.
uniprot
proteins