Spesp1
entrez
66712
canonical
uniprot
Q9D5A0
canonical
ensembl
ENSMUSG00000046846
resolver
ensp
ENSMUSP00000058522
resolver
enst
ENSMUST00000056949
resolver
genesymbol
Spesp1
resolver
uniprot
Q9D5X8
resolver
uniprot_entry
SPESP_MOUSE
resolver
uniprot_sec
Q9D5X8
resolver
amino_acid_sequence
MKLVVLVALWLWPSSLLAYPTITVLPDEEQNLNHYVHILQNLIMSVPTKEQDLGKKLSSSRTVDSAEPRSLASKVLLTPGLVSAQDVTPESDVLIRPVDETTNSRTRGFTLRRRRTQSTAFWSIRPNNISVVLRTEEPFIEKEPEPELESSRLPTEPEPELEPEPEPVAESRQMSEPEEELVTSTTPNKELTGTSRISSMATQPANTQATRITVTVKTTSTMDVSTDSEDVPQLSGQSEIPSAEDLPGRHSLNTRHEDILKKISNINAEIQQGLLGGNNSPEFKEFIKASREHLKRSLALAAAAEHKLEQMYGSNVFPEGRTSDPDNDMEMIINMLYNSRSKLSDYFNIKRVPSELREKASVVNAELRKILCVDQVEMQSLIKKLLSNNMKILNILNVP
uniprot
proteins
function
FUNCTION: Involved in fertilization ability of sperm. {ECO:0000269|PubMed:20375058, ECO:0000269|PubMed:25761597}.
uniprot
proteins
mass_dalton
44702
uniprot
proteins
post_translational_modification
PTM: Glycosylated. In testis there are two predominant forms of 77- and 67-kDa and a form of 47-kDa, whereas in epididymal sperm from caput, corpus, and cauda there are two forms of 47- and 43-kDa. Testis forms contain complex carbohydrate residues. Epididymal sperm forms are N-glycosylated. Then undergoes significant glycosylation in the testis and that the majority of these glycoconjugates are removed by the time sperm reach the caput epididymis. {ECO:0000269|PubMed:25761597}.
uniprot
proteins
protein_family
SPESP1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20375058
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25761597
uniprot
proteins
sequence_length
399
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:20375058}. Note=Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the maturation phase) (By similarity). After acrosome reaction localizes to the equatorial segment region in both noncapacitated and capacitated, acrosome-reacted sperm (PubMed:25761597). {ECO:0000250|UniProtKB:Q6UW49, ECO:0000269|PubMed:25761597}.
uniprot
proteins