Dpep2
entrez
291984
canonical
uniprot
Q5M872
canonical
ensembl
ENSRNOG00000023303
resolver
ensembl
ENSRNOG00055018202
resolver
ensembl
ENSRNOG00060012459
resolver
ensembl
ENSRNOG00065012422
resolver
ensp
ENSRNOP00000031955
resolver
ensp
ENSRNOP00055024840
resolver
ensp
ENSRNOP00060016675
resolver
ensp
ENSRNOP00065015526
resolver
enst
ENSRNOT00000034722
resolver
enst
ENSRNOT00055030852
resolver
enst
ENSRNOT00060021133
resolver
enst
ENSRNOT00065020225
resolver
genesymbol
Dpep2
resolver
uniprot_entry
DPEP2_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by L-penicillamine. {ECO:0000250|UniProtKB:Q8C255}.
uniprot
proteins
amino_acid_sequence
MSLKGLEGHWVLSQVFLLVVVLLLLGPSEPLIRAQTKPGIADASTAPSPLRTLTKPAIFSIPTTPGNPNFPDLRDRTRALMQDFPLIDGHNDLPLVLRQFYQNGLQDTNLRNFTHGQTSLNRLKDGFVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRMCASYSELELVTSVQALNSTQKLACLIGVEGGHSLDNSLAVLRSFYLLGVRYLTLTHTCNTPWAESSSKDVHSFYSSVKGLTSFGEKVVAEMNRLGMMIDLSHVSDATARQALEVSQAPVIFSHSAARAVCPNARNLPDDILQLLKKNGGIVMVTFAVGVLPCNPLANVSTVADHFDHIRTVIGSEFIGVGGDYDGTKQFPQGLEDVSTYPVLIEELLRRGWGEQELQGVLRGNLLRVFRQVEQVREKNKWQSPLEDMIPEEQLDSACHSVLPHRRQYPEKDPPETPDSHTHKLSPKMPYSKSSPLRASSLTIMATFLGLLI
uniprot
proteins
ec_number
3.4.13.19
uniprot
proteins
function
FUNCTION: Dipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) and cystinyl-bis-glycine. {ECO:0000250|UniProtKB:Q9H4A9}.; FUNCTION: Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF-kappa-B inflammatory signaling pathway. {ECO:0000250|UniProtKB:Q8C255}.
uniprot
proteins
mass_dalton
53285
uniprot
proteins
protein_family
Metallo-dependent hydrolases superfamily
uniprot
proteins
protein_family
Peptidase M19 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
481
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q8C255}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q8C255}.
uniprot
proteins