Apoc3
entrez
11814
canonical
uniprot
P33622
canonical
ensembl
ENSMUSG00000032081
resolver
ensp
ENSMUSP00000034586
resolver
ensp
ENSMUSP00000113058
resolver
ensp
ENSMUSP00000113126
resolver
enst
ENSMUST00000034586
resolver
enst
ENSMUST00000118649
resolver
enst
ENSMUST00000121916
resolver
genesymbol
Apoc3
resolver
uniprot
A0A0R4J1N3
resolver
uniprot
E9QP56
resolver
uniprot
Q8VC58
resolver
uniprot
Q9CPP9
resolver
uniprot_entry
A0A0R4J1N3_MOUSE
resolver
uniprot_entry
APOC3_MOUSE
resolver
uniprot_entry
E9QP56_MOUSE
resolver
uniprot_sec
Q8VC58
resolver
uniprot_sec
Q9CPP9
resolver
amino_acid_sequence
MQPRTLLTVALLALLASARAEEVEGSLLLGSVQGYMEQASKTVQDALSSVQESDIAVVARGWMDNHFRFLKGYWSKFTDKFTGFWDSNPEDQPTPAIES
uniprot
proteins
function
FUNCTION: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners. {ECO:0000250|UniProtKB:P02656}.
uniprot
proteins
mass_dalton
10982
uniprot
proteins
post_translational_modification
PTM: The most abundant glycoforms are characterized by an O-linked disaccharide galactose linked to N-acetylgalactosamine (Gal-GalNAc), further modified with up to 3 sialic acid residues. Less abundant glycoforms are characterized by more complex and fucosylated glycan moieties. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan. {ECO:0000250|UniProtKB:P02656}.
uniprot
proteins
protein_family
Apolipoprotein C3 family
uniprot
proteins
pubmed
1478650
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16876491
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
99
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P02656}.
uniprot
proteins