Nacc2
entrez
296583
canonical
uniprot
Q562B4
canonical
ensembl
ENSRNOG00000018231
resolver
ensp
ENSRNOP00000070139
resolver
enst
ENSRNOT00000087651
resolver
genesymbol
Nacc2
resolver
genesymbol_syn
Btbd14a
resolver
uniprot
G3V8D3
resolver
uniprot_entry
G3V8D3_RAT
resolver
uniprot_entry
NACC2_RAT
resolver
amino_acid_sequence
MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGTVPPACFQQILSFCYTGKLTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAMIEDASSEPQSPCNQLQPATAAYATSPSVPIPLLTRVKHEAMEMPPATGPGLASKRPLDTGPRDGVAVATGAAGTPGTAPLKLPRVSYYGVPSLATLIPSIQQVPYPQGERTSPGASSLPTTDSSTSYHNEDEDDDEAYDTMVEEQYGQMYIKATGNYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRSVMGASAASLPLDPEFPSAASQVFEQRIYAERRNDAATIVALRTDAVNVDLSTSANPAFEANEEVDGAGSVIQEVAAPEQLPADGQSSPQAFEQGNTSSSRPQTPVATATRRPEGTYAGTL
uniprot
proteins
function
FUNCTION: Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
63100
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
585
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Note=Predominantly associated with chromatin. {ECO:0000250}.
uniprot
proteins