Tssc4
entrez
56844
canonical
uniprot
Q9JHE7
canonical
ensembl
ENSMUSG00000045752
resolver
ensp
ENSMUSP00000056582
resolver
ensp
ENSMUSP00000101540
resolver
ensp
ENSMUSP00000137399
resolver
ensp
ENSMUSP00000146914
resolver
genesymbol
Tssc4
resolver
genesymbol_syn
tssc4
resolver
uniprot
Q9JHE9
resolver
uniprot_entry
Q9JHE9_MOUSE
resolver
uniprot_entry
TSSC4_MOUSE
resolver
amino_acid_sequence
MAETEAGLEADEPTEDDTLPSDTVSLSDSDSDLSLPSGVEVQVLSPERLSEEGQEDSGPEDPPSPPTGTLTTAVQPFHLRGMSSTFSQRSHSIFDCLESAARQAPCSAPQTSVSDNGSFRRPVTPPSQTPARGLSRVHGNTGPTRVLPVPDYVSHPERWTKYSLEDVSEASEQSNRDAALAFLSSRSQVSHTDYVPSFNQDPSSCGEGRVVFTKPVRDSEARAERKRVLKKGVGSGAGGEAAVELAHLAGPEAEEWSGHQGQPEVVVPSEAAHPESSSGPIGVKAVGFHGSKKRSRDHFRNRDGNPGGPGSERGPSV
uniprot
proteins
function
FUNCTION: Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus. Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing. Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP. {ECO:0000250|UniProtKB:Q9Y5U2}.
uniprot
proteins
mass_dalton
33569
uniprot
proteins
protein_family
TSSC4 family
uniprot
proteins
pubmed
10907850
uniprot
proteins
pubmed
10915772
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y5U2}. Cytoplasm {ECO:0000250|UniProtKB:Q9Y5U2}. Note=Shuttles between the cytoplasm and the nucleus, associated with the U5 snRNP. {ECO:0000250|UniProtKB:Q9Y5U2}.
uniprot
proteins