Tmem9b
entrez
56786
canonical
uniprot
Q9JJR8
canonical
ensembl
ENSMUSG00000031021
resolver
ensp
ENSMUSP00000033333
resolver
enst
ENSMUST00000033333
resolver
genesymbol
Tmem9b
resolver
uniprot_entry
TMM9B_MOUSE
resolver
amino_acid_sequence
MASLWCGNLLRLGSGLSMSCLALSVLLLAQLTGAAKNFEDVRCKCICPPYKENPGHIYNKNISQKDCDCLHVVEPMPVRGPDVEAYCLRCECKYEERSSVTIKVTIIIYLSILGLLLLYMVYLTLVEPILKRRLFGHSQLLQSDDDVGDHQPFANAHDVLARSRSRANVLNKVEYAQQRWKLQVQEQRKSVFDRHVVLS
uniprot
proteins
function
FUNCTION: Enhances production of pro-inflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways. {ECO:0000250|UniProtKB:Q9NQ34}.
uniprot
proteins
mass_dalton
22607
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q9NQ34}.
uniprot
proteins
protein_family
TMEM9 family
uniprot
proteins
pubmed
11528127
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
199
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q9NQ34}; Single-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000250|UniProtKB:Q9NQ34}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins