STRN4
entrez
29888
canonical
uniprot
Q9NRL3
canonical
ensembl
ENSG00000090372
resolver
ensp
ENSP00000263280
resolver
ensp
ENSP00000375777
resolver
ensp
ENSP00000440901
resolver
ensp
ENSP00000692743
resolver
ensp
ENSP00000692745
resolver
ensp
ENSP00000731194
resolver
ensp
ENSP00000731196
resolver
enst
ENST00000539396
resolver
genesymbol
STRN4
resolver
genesymbol_syn
ZIN
resolver
hgnc
HGNC:15721
resolver
uniprot
A0A024R0V2
resolver
uniprot
B4DQH7
resolver
uniprot
F5GYK2
resolver
uniprot
F8VYA6
resolver
uniprot
Q59GV6
resolver
uniprot
Q8NE53
resolver
uniprot_entry
F5GYK2_HUMAN
resolver
uniprot_entry
Q59GV6_HUMAN
resolver
uniprot_entry
STRN4_HUMAN
resolver
uniprot_sec
A0A024R0V2
resolver
uniprot_sec
B4DQH7
resolver
uniprot_sec
F8VYA6
resolver
uniprot_sec
Q8NE53
resolver
amino_acid_sequence
MMEERAAAAVAAAASSCRPLGSGAGPGPTGAAPVSAPAPGPGPAGKGGGGGGSPGPTAGPEPLSLPGILHFIQHEWARFEAEKARWEAERAELQAQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKKADVSEQVSNGPVESVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGRSLELNGAVEPSEGAPRAPPGPAGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLGQIPFLQNCEDEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGEGAPDPRRCTVDGSPHELESRRVKLQGILADLRDVDGLPPKVTGPPPGTPQPRPHEDVFIMDTIGGGEVSLGDLADLTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEPAHIVASFRSGDTVLYDMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSMVAHLDAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVACHPSKALIASAGADALAKVFV
uniprot
proteins
function
FUNCTION: Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kinase (STRIPAK) complexes (PubMed:18782753, PubMed:32640226). STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling (PubMed:32640226). Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (Probable). Key regulator of the expanded Hippo signaling pathway by interacting and allowing the inhibition of MAP4K kinases by the STRIPAK complex (PubMed:32640226). {ECO:0000269|PubMed:18782753, ECO:0000269|PubMed:32640226, ECO:0000305|PubMed:26876214}.
uniprot
proteins
mass_dalton
80596
uniprot
proteins
protein_family
WD repeat striatin family
uniprot
proteins
pubmed
10748158
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18782753
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26876214
uniprot
proteins
pubmed
32640226
uniprot
proteins
sequence_length
753
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305|PubMed:18782753}.
uniprot
proteins