HILPDA
entrez
29923
canonical
uniprot
Q9Y5L2
canonical
ensembl
ENSG00000135245
resolver
ensp
ENSP00000257696
resolver
ensp
ENSP00000388871
resolver
ensp
ENSP00000586236
resolver
ensp
ENSP00000586237
resolver
enst
ENST00000257696
resolver
enst
ENST00000435296
resolver
enst
ENST00000916177
resolver
enst
ENST00000916178
resolver
genesymbol
HILPDA
resolver
genesymbol_syn
C7orf68
resolver
genesymbol_syn
HIG2
resolver
hgnc
HGNC:28859
resolver
uniprot
A4D0Z5
resolver
uniprot
Q52LY5
resolver
uniprot
Q53HJ7
resolver
uniprot_entry
HLPDA_HUMAN
resolver
uniprot_sec
A4D0Z5
resolver
uniprot_sec
Q52LY5
resolver
uniprot_sec
Q53HJ7
resolver
amino_acid_sequence
MKHVLNLYLLGVVLTLLSIFVRVMESLEGLLESPSPGTSWTTRSQLANTEPTKGLPDHPSRSM
uniprot
proteins
function
FUNCTION: Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation. {ECO:0000269|PubMed:15930302, ECO:0000269|PubMed:20624928}.
uniprot
proteins
mass_dalton
6950
uniprot
proteins
mutagenesis
MUTAGEN 8..9; /note="YL->DD: Loss of targeting to lipid droplets and elimination of protein."; /evidence="ECO:0000269|PubMed:20624928"; MUTAGEN 41; /note="T->K: No effect on lipid droplet targeting or protein expression; when associated with K-44."; /evidence="ECO:0000269|PubMed:20624928"; MUTAGEN 44; /note="S->K: No effect on lipid droplet targeting or protein expression; when associated with K-41."; /evidence="ECO:0000269|PubMed:20624928
uniprot
proteins
pubmed
10690527
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15930302
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20624928
uniprot
proteins
pubmed
21614900
uniprot
proteins
sequence_length
63
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lipid droplet. Secreted. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..23; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins