CCKAR
entrez
886
canonical
uniprot
P32238
canonical
ensembl
ENSG00000163394
resolver
ensp
ENSP00000295589
resolver
enst
ENST00000295589
resolver
genesymbol
CCKAR
resolver
genesymbol_syn
CCKRA
resolver
hgnc
HGNC:1570
resolver
uniprot
B2R9Z5
resolver
uniprot_entry
CCKAR_HUMAN
resolver
uniprot_sec
B2R9Z5
resolver
amino_acid_sequence
MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSHMSASVPPQ
uniprot
proteins
function
FUNCTION: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
uniprot
proteins
mass_dalton
47841
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10555959
uniprot
proteins
pubmed
10682840
uniprot
proteins
pubmed
11300760
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7557108
uniprot
proteins
pubmed
8343165
uniprot
proteins
pubmed
8503909
uniprot
proteins
sequence_length
428
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 42..67; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 78..104; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 116..137; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 158..178; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 211..234; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 350..373; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins