Gfer
entrez
11692
canonical
uniprot
P56213
canonical
ensembl
ENSMUSG00000040888
resolver
ensp
ENSMUSP00000049186
resolver
ensp
ENSMUSP00000157116
resolver
ensp
ENSMUSP00000157249
resolver
ensp
ENSMUSP00000157329
resolver
ensp
ENSMUSP00000229816
resolver
ensp
ENSMUSP00000229820
resolver
enst
ENSMUST00000046839
resolver
enst
ENSMUST00000234197
resolver
enst
ENSMUST00000234235
resolver
enst
ENSMUST00000234520
resolver
genesymbol
Gfer
resolver
genesymbol_syn
Alr
resolver
uniprot
A0A3Q4EGL6
resolver
uniprot
Q8CIF8
resolver
uniprot
Q9JJE6
resolver
uniprot_entry
A0A3Q4EGL6_MOUSE
resolver
uniprot_entry
ALR_MOUSE
resolver
uniprot_sec
Q8CIF8
resolver
uniprot_sec
Q9JJE6
resolver
amino_acid_sequence
MAAPSEPAGFPRGSRFSFLPGGARSEMTDDLVTDARGRGARHRDDTTPAAAPAPQGLEHGKRPCRACVDFKSWMRTQQKRDIKFREDCPQDREELGRHTWAFLHTLAAYYPDRPTPEQQQDMAQFIHIFSKFYPCEECAEDIRKRIGRNQPDTSTRVSFSQWLCRLHNEVNRKLGKPDFDCSRVDERWRDGWKDGSCD
uniprot
proteins
ec_number
1.8.3.2
uniprot
proteins
function
FUNCTION: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen (By similarity). {ECO:0000250|UniProtKB:P55789}.
uniprot
proteins
mass_dalton
22877
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8900538
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:P55789}. Mitochondrion {ECO:0000250|UniProtKB:P55789}.
uniprot
proteins