Slmap
entrez
83997
canonical
uniprot
Q3URD3
canonical
ensembl
ENSMUSG00000021870
resolver
ensp
ENSMUSP00000046956
resolver
ensp
ENSMUSP00000087836
resolver
ensp
ENSMUSP00000107949
resolver
ensp
ENSMUSP00000107950
resolver
ensp
ENSMUSP00000117276
resolver
ensp
ENSMUSP00000117816
resolver
ensp
ENSMUSP00000262476
resolver
ensp
ENSMUSP00000262477
resolver
ensp
ENSMUSP00000262478
resolver
ensp
ENSMUSP00000262479
resolver
ensp
ENSMUSP00000262480
resolver
ensp
ENSMUSP00000262481
resolver
ensp
ENSMUSP00000262482
resolver
ensp
ENSMUSP00000262483
resolver
ensp
ENSMUSP00000262484
resolver
ensp
ENSMUSP00000262485
resolver
ensp
ENSMUSP00000262486
resolver
ensp
ENSMUSP00000262487
resolver
ensp
ENSMUSP00000262489
resolver
ensp
ENSMUSP00000262490
resolver
ensp
ENSMUSP00000262491
resolver
ensp
ENSMUSP00000262492
resolver
ensp
ENSMUSP00000262493
resolver
ensp
ENSMUSP00000262496
resolver
ensp
ENSMUSP00000262497
resolver
enst
ENSMUST00000090359
resolver
enst
ENSMUST00000112330
resolver
genesymbol
Slmap
resolver
genesymbol_syn
Kiaa1601
resolver
genesymbol_syn
Slap
resolver
uniprot
D3Z7V3
resolver
uniprot
H7BX64
resolver
uniprot
Q3TLP0
resolver
uniprot
Q3UIZ6
resolver
uniprot
Q6ZPL8
resolver
uniprot
Q8VC86
resolver
uniprot
Q9EQ03
resolver
uniprot_entry
D3Z7V3_MOUSE
resolver
uniprot_entry
H7BX64_MOUSE
resolver
uniprot_entry
SLMAP_MOUSE
resolver
uniprot_sec
Q3TLP0
resolver
uniprot_sec
Q3UIZ6
resolver
uniprot_sec
Q6ZPL8
resolver
uniprot_sec
Q8VC86
resolver
uniprot_sec
Q9EQ03
resolver
amino_acid_sequence
MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSLGIQVDDFLPKINGSTEKEHLLSKSGGDCTFIHQFLECQKKLMVQGHLTKVVEESKLSKENQAKAKESDLSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGTQSETEAKQDIQHLRKELVEAQELARTSKQKCFELQALLEEERKAYRNQVEESAKQIQVLQVQLQKLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLRQAAAEAVSERDTDFVSLQEELKKVRAELEGWRKAASEYENEIRSLQSSFQLRCQQCEDQQREEATRLQGELEKLKKEWDVLETECHSLKKENVLLSSELQRQEKELHNSQKQSFELTSDLSILQMTRKELEKQVGSLKEQHLRDAADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKDNLKLLREKGNNKPWPWMPMLAALVAVTAMVLYVPGLARASP
uniprot
proteins
function
FUNCTION: Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth (By similarity). May play a role during myoblast fusion (PubMed:15591093). {ECO:0000250|UniProtKB:Q14BN4, ECO:0000269|PubMed:15591093}.
uniprot
proteins
mass_dalton
96933
uniprot
proteins
protein_family
SLMAP family
uniprot
proteins
pubmed
10986292
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15086317
uniprot
proteins
pubmed
15126628
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15591093
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
845
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane, sarcolemma {ECO:0000269|PubMed:15086317, ECO:0000269|PubMed:15591093}; Single-pass type IV membrane protein {ECO:0000269|PubMed:15086317, ECO:0000269|PubMed:15591093}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000269|PubMed:15086317}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:15086317}. Note=Membrane-associated. Distributed in the transverse tubules and near the junctional sarcoplasmic reticulum. Detected along the Z- and M-lines in cardiomyocytes. {ECO:0000269|PubMed:15086317}.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15126628}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q14BN4}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q14BN4}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q14BN4}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q14BN4}. Note=Localizes to the centrosomes in a microtubule-dependent manner. {ECO:0000269|PubMed:15126628}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15126628}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q14BN4}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q14BN4}. Note=Localizes to the centrosomes in a microtubule-dependent manner (PubMed:15126628). Do not localize at the mitochondrial membrane (By similarity). {ECO:0000250|UniProtKB:Q14BN4, ECO:0000269|PubMed:15126628}.; SUBCELLULAR LOCATION: [Isoform 3]: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q14BN4}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q14BN4}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q14BN4}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q14BN4}.; SUBCELLULAR LOCATION: [Isoform 4]: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q14BN4}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q14BN4}. Note=Do not localize at the mitochondrial membrane. {ECO:0000250|UniProtKB:Q14BN4}.
uniprot
proteins
transmembrane_region
TRANSMEM 820..840; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255"; TRANSMEM Q3URD3-2:28..85; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255"; TRANSMEM Q3URD3-4:339..359; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins