RAP1GAP2
entrez
23108
canonical
uniprot
Q684P5
canonical
ensembl
ENSG00000132359
resolver
ensp
ENSP00000254695
resolver
ensp
ENSP00000389824
resolver
ensp
ENSP00000439688
resolver
ensp
ENSP00000490321
resolver
ensp
ENSP00000513294
resolver
ensp
ENSP00000513295
resolver
enst
ENST00000637138
resolver
enst
ENST00000697391
resolver
enst
ENST00000697392
resolver
genesymbol
RAP1GAP2
resolver
genesymbol_syn
GARNL4
resolver
genesymbol_syn
KIAA1039
resolver
genesymbol_syn
RAP1GA2
resolver
hgnc
HGNC:29176
resolver
uniprot
A0A1B0GV05
resolver
uniprot
A0A8V8TKZ8
resolver
uniprot
A0A8V8TL16
resolver
uniprot
B2RTY5
resolver
uniprot
Q684P4
resolver
uniprot
Q6AI00
resolver
uniprot
Q6ZVF0
resolver
uniprot
Q9UPW2
resolver
uniprot_entry
A0A1B0GV05_HUMAN
resolver
uniprot_entry
A0A8V8TKZ8_HUMAN
resolver
uniprot_entry
A0A8V8TL16_HUMAN
resolver
uniprot_entry
RPGP2_HUMAN
resolver
uniprot_sec
B2RTY5
resolver
uniprot_sec
Q684P4
resolver
uniprot_sec
Q6AI00
resolver
uniprot_sec
Q6ZVF0
resolver
uniprot_sec
Q9UPW2
resolver
amino_acid_sequence
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGPEEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDKLSHASSGAGH
uniprot
proteins
function
FUNCTION: GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000269|PubMed:15632203}.
uniprot
proteins
mass_dalton
80056
uniprot
proteins
mutagenesis
MUTAGEN 7; /note="S->A: Abolishes phosphorylation by PKG/PRKG1."; /evidence="ECO:0000269|PubMed:15632203"; MUTAGEN 357; /note="N->A: Abolishes GAP activity."; /evidence="ECO:0000269|PubMed:15632203
uniprot
proteins
post_translational_modification
PTM: In vitro phosphorylated by cGMP-dependent protein kinase 1 (cGKI) at Ser-7; the phosphorylation probably does not regulate GAP activity. {ECO:0000269|PubMed:15632203}.
uniprot
proteins
pubmed
10470851
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15632203
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
730
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15632203}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:15632203}.
uniprot
proteins