FGFR1OP2
entrez
26127
canonical
uniprot
Q9NVK5
canonical
ensembl
ENSG00000111790
resolver
ensp
ENSP00000229395
resolver
ensp
ENSP00000323763
resolver
ensp
ENSP00000437556
resolver
genesymbol
FGFR1OP2
resolver
hgnc
HGNC:23098
resolver
uniprot
Q6R955
resolver
uniprot
Q8N5L7
resolver
uniprot
Q9P034
resolver
uniprot
Q9UFK8
resolver
uniprot_entry
FGOP2_HUMAN
resolver
uniprot_sec
Q6R955
resolver
uniprot_sec
Q8N5L7
resolver
uniprot_sec
Q9P034
resolver
uniprot_sec
Q9UFK8
resolver
amino_acid_sequence
MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDDASESTSLSALVTNSDLSLRKS
uniprot
proteins
disease_involvement
DISEASE: Note=A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
uniprot
proteins
function
FUNCTION: May be involved in wound healing pathway. {ECO:0000250}.
uniprot
proteins
mass_dalton
29426
uniprot
proteins
protein_family
SIKE family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15034873
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16946300
uniprot
proteins
pubmed
17389761
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
253
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins