HS6ST2
entrez
90161
canonical
uniprot
Q96MM7
canonical
ensembl
ENSG00000171004
resolver
ensp
ENSP00000359870
resolver
ensp
ENSP00000359873
resolver
ensp
ENSP00000384013
resolver
ensp
ENSP00000429473
resolver
ensp
ENSP00000491722
resolver
genesymbol
HS6ST2
resolver
hgnc
HGNC:19133
resolver
uniprot
B9WRT4
resolver
uniprot
B9WRT5
resolver
uniprot
E9PDY5
resolver
uniprot
Q2TB13
resolver
uniprot
Q4VC07
resolver
uniprot
Q6PIC4
resolver
uniprot
Q86SM9
resolver
uniprot
Q8N3T4
resolver
uniprot
Q8NBN4
resolver
uniprot
Q96SJ4
resolver
uniprot_entry
H6ST2_HUMAN
resolver
uniprot_sec
B9WRT4
resolver
uniprot_sec
B9WRT5
resolver
uniprot_sec
E9PDY5
resolver
uniprot_sec
Q2TB13
resolver
uniprot_sec
Q4VC07
resolver
uniprot_sec
Q6PIC4
resolver
uniprot_sec
Q86SM9
resolver
uniprot_sec
Q8N3T4
resolver
uniprot_sec
Q8NBN4
resolver
uniprot_sec
Q96SJ4
resolver
amino_acid_sequence
MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGSVEKWR
uniprot
proteins
disease_involvement
DISEASE: Paganini-Miozzo syndrome (MRXSPM) [MIM:301025]: An X-linked, syndromic, neurodevelopmental disorder characterized by intellectual disability, global developmental delay, severe myopia, and mild facial dysmorphism. {ECO:0000269|PubMed:30471091}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
2.8.2.-
uniprot
proteins
function
FUNCTION: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. {ECO:0000269|PubMed:12492399, ECO:0000269|PubMed:30471091}.
uniprot
proteins
mass_dalton
69130
uniprot
proteins
protein_family
Sulfotransferase 6 family
uniprot
proteins
pubmed
12492399
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
30471091
uniprot
proteins
sequence_length
605
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..27; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins