Icam5
entrez
313785
canonical
uniprot
A6JNN4
canonical
ensembl
ENSRNOG00000020694
resolver
ensembl
ENSRNOG00055012313
resolver
ensembl
ENSRNOG00060025842
resolver
ensembl
ENSRNOG00065012018
resolver
ensp
ENSRNOP00000028096
resolver
ensp
ENSRNOP00055016931
resolver
ensp
ENSRNOP00060037075
resolver
ensp
ENSRNOP00065014982
resolver
enst
ENSRNOT00000028096
resolver
enst
ENSRNOT00055020959
resolver
enst
ENSRNOT00060044724
resolver
enst
ENSRNOT00065019546
resolver
genesymbol
Icam5
resolver
genesymbol_syn
Tlcn
resolver
uniprot
D4A435
resolver
uniprot_entry
D4A435_RAT
resolver
uniprot_entry
ICAM5_RAT
resolver
amino_acid_sequence
MPGPSPGLRRTLLGLWAALGLGILGISAVALEPFWADLQPRVALVERGGSLWLNCSTNCPRPERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCFFRCARRTLQARGLIRTFQRPDRVELVPLPPWQPVGENFTLSCRVPGAGPRASLTLTLLRGGQELIRRSFVGEPPRARGAMLTATVLARREDHRANFSCLAELDLRPHGLGLFANSSAPRQLRTFAMPPLSPSLIAPRFLEVGSERPVTCTLDGLFPAPEAGVYLSLGDQRLHPNVTLDGESLVATATATASEEQEGTKQLMCIVTLGGESRETQENLTVYSFPAPLLTLSEPEAPEGKMVTVSCWAGARALVTLEGIPAAVPGQPAELQLNVTKNDDKRGFFCDAALDVDGETLRKNQSSELRVLYAPRLDDLDCPRSWTWPEGPEQTLHCEARGNPEPSVHCARPDGGAVLALGLLGPVTRALAGTYRCTAINGQGQAVKDVTLTVEYAPALDSVGCPERITWLEGTEASLSCVAHGVPPPSVSCVRSGKEEVMEGPLRVAREHAGTYRCEAINARGSAAKNVAVTVEYGPSFEELGCPSNWTWVEGSGKLFSCEVDGKPEPRVECVGSEGASEGVVLPLVSSNSGSRNSMTPGNLSPGIYLCNATNRHGSTVKTVVVSAESPPQMDESSCPSHQTWLEGAEATALACSARGRPSPRVRCSREGAARLERLQVSREDAGTYLCVATNAHGTDSRTVTVGVEYRPVVAELAASPPSVRPGGNFTLTCRAEAWPPAQISWRAPPGALNLGLSSNNSTLSVAGAMGSHGGEYECAATNAHGRHARRITVRVAGPWLWVAVGGAAGGAALLAAGAGLAFYVQSTACKKGEYNVQEAESSGEAVCLNGAGGTPGAEGGAETPGTAESPADGEVFAIQLTSS
uniprot
proteins
function
FUNCTION: Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring neuron cell-leukocyte adhesion (PubMed:10741396). Creates homophilic cell adhesion promoting dendritogenesis and arborization of hippocampal neurons (PubMed:10893271). {ECO:0000269|PubMed:10741396, ECO:0000269|PubMed:10893271}.
uniprot
proteins
mass_dalton
96905
uniprot
proteins
protein_family
ICAM family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
10741396
uniprot
proteins
pubmed
10893271
uniprot
proteins
sequence_length
917
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q60625}; Single-pass membrane protein {ECO:0000255}. Cell projection {ECO:0000250|UniProtKB:Q9UMF0}. Cell projection, uropodium {ECO:0000250|UniProtKB:Q9UMF0}. Cell projection, dendritic spine membrane {ECO:0000250|UniProtKB:Q60625}. Note=At uropodium and cell-cell contact sites creates homophilic adhesion. {ECO:0000250|UniProtKB:Q9UMF0}.
uniprot
proteins
transmembrane_region
TRANSMEM 834..854; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins