STX8
entrez
9482
canonical
uniprot
Q9UNK0
canonical
ensembl
ENSG00000170310
resolver
ensp
ENSP00000305255
resolver
enst
ENST00000306357
resolver
genesymbol
STX8
resolver
hgnc
HGNC:11443
resolver
uniprot
O60712
resolver
uniprot
Q53XT8
resolver
uniprot_entry
STX8_HUMAN
resolver
uniprot_sec
O60712
resolver
uniprot_sec
Q53XT8
resolver
amino_acid_sequence
MAPDPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVSTHQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGAPNPWLFEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNETRRVNMVDRKSASCGMIMVILLLLVAIVVVAVWPTN
uniprot
proteins
function
FUNCTION: Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.
uniprot
proteins
mass_dalton
26907
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by HECTD3. {ECO:0000250}.
uniprot
proteins
protein_family
Syntaxin family
uniprot
proteins
pubmed
10198254
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
9852078
uniprot
proteins
sequence_length
236
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 216..232; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins