Them4
entrez
361992
canonical
uniprot
Q566R0
canonical
ensembl
ENSRNOG00000020829
resolver
ensembl
ENSRNOG00055032126
resolver
ensembl
ENSRNOG00060013260
resolver
ensembl
ENSRNOG00065025206
resolver
ensp
ENSRNOP00000028260
resolver
ensp
ENSRNOP00055045809
resolver
ensp
ENSRNOP00060017926
resolver
ensp
ENSRNOP00065035612
resolver
enst
ENSRNOT00000028260
resolver
enst
ENSRNOT00055055534
resolver
enst
ENSRNOT00060022606
resolver
enst
ENSRNOT00065043419
resolver
genesymbol
Them4
resolver
uniprot_entry
THEM4_RAT
resolver
amino_acid_sequence
MLRSCAMRLRTLGATPARRPEATRRLFSSEEVVCKDYALPNPSWTKDLRLLFDQFMKKCEDGSWKRLPSYRQNPPQALQEFQTHFVDSKFKKEEQMSKAQQFTRSLEEGLGFEYAMFYNKAEKRIVCLFQGGLHLQGMPGFVHGGAIATIIDITAGMCAFSEGIVMTANLNIDYKKPIPLLSVVVVNSQLQKIEGRKLFVSCTIQSTDEKTLHTQATALFIKLDPDKPLT
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
function
FUNCTION: Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism (By similarity). Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity (By similarity). {ECO:0000250|UniProtKB:Q5T1C6}.
uniprot
proteins
mass_dalton
26089
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250|UniProtKB:Q5T1C6}.
uniprot
proteins
protein_family
THEM4/THEM5 thioesterase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
230
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5T1C6}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:Q5T1C6}. Cytoplasm {ECO:0000250|UniProtKB:Q5T1C6}. Mitochondrion {ECO:0000250|UniProtKB:Q5T1C6}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q5T1C6}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q5T1C6}. Mitochondrion intermembrane space {ECO:0000250|UniProtKB:Q5T1C6}. Note=Released from the mitochondria into the cytosol in response to apoptotic stimuli. {ECO:0000250|UniProtKB:Q5T1C6}.
uniprot
proteins