FHOD1
entrez
29109
canonical
uniprot
Q9Y613
canonical
ensembl
ENSG00000135723
resolver
ensp
ENSP00000258201
resolver
ensp
ENSP00000580094
resolver
ensp
ENSP00000580100
resolver
ensp
ENSP00000683916
resolver
enst
ENST00000258201
resolver
genesymbol
FHOD1
resolver
genesymbol_syn
FHOS
resolver
genesymbol_syn
FHOS1
resolver
hgnc
HGNC:17905
resolver
uniprot
A0A068F7M9
resolver
uniprot
Q59F76
resolver
uniprot
Q6Y1F2
resolver
uniprot
Q76MS8
resolver
uniprot
Q8N521
resolver
uniprot_entry
A0A068F7M9_HUMAN
resolver
uniprot_entry
FHOD1_HUMAN
resolver
uniprot_sec
Q59F76
resolver
uniprot_sec
Q6Y1F2
resolver
uniprot_sec
Q76MS8
resolver
uniprot_sec
Q8N521
resolver
amino_acid_sequence
MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHRLLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSVDTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRPEDTTHNRRSRGMVQSSSPIMPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGPGLEV
uniprot
proteins
function
FUNCTION: Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing. {ECO:0000269|PubMed:14576350, ECO:0000269|PubMed:15878344, ECO:0000269|PubMed:18694941}.
uniprot
proteins
mass_dalton
126551
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by ROCK1. {ECO:0000269|PubMed:18694941}.
uniprot
proteins
protein_family
Formin homology family
uniprot
proteins
pubmed
10352228
uniprot
proteins
pubmed
12665801
uniprot
proteins
pubmed
14576350
uniprot
proteins
pubmed
15138285
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15878344
uniprot
proteins
pubmed
16361249
uniprot
proteins
pubmed
18088087
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
18694941
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
1164
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic.
uniprot
proteins