Atp1a2
entrez
24212
canonical
uniprot
P06686
canonical
ensembl
ENSRNOG00000007290
resolver
ensembl
ENSRNOG00055021772
resolver
ensembl
ENSRNOG00060021783
resolver
ensembl
ENSRNOG00065026140
resolver
ensp
ENSRNOP00000054947
resolver
ensp
ENSRNOP00055030496
resolver
ensp
ENSRNOP00060032272
resolver
ensp
ENSRNOP00065037410
resolver
enst
ENSRNOT00000058143
resolver
enst
ENSRNOT00055037412
resolver
enst
ENSRNOT00060039034
resolver
enst
ENSRNOT00065045622
resolver
genesymbol
Atp1a2
resolver
uniprot_entry
AT1A2_RAT
resolver
amino_acid_sequence
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGALLCFLAYGILAAMEDEPSNDNLYLGIVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGQTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTTNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
uniprot
proteins
ec_number
7.2.2.13
uniprot
proteins
function
FUNCTION: Catalytic subunit of the Na(+)/K(+)-ATPase that hydrolyzes ATP to exchange ions across the plasma membrane, exporting 3 Na(+) and importing 2 K(+) per cycle (By similarity). It undergoes ATP-driven conformational changes that allow alternating binding and release of Na(+) and K(+) ions across the membrane (By similarity). This process maintains essential Na(+) and K(+) gradients for membrane potential and cellular function (By similarity). {ECO:0000250|UniProtKB:P05023, ECO:0000250|UniProtKB:P50993}.
uniprot
proteins
mass_dalton
112217
uniprot
proteins
protein_family
Cation transport ATPase (P-type) (TC 3.A.3) family
uniprot
proteins
protein_family
Type IIC subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1846906
uniprot
proteins
pubmed
2170235
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
23532852
uniprot
proteins
pubmed
3028470
uniprot
proteins
sequence_length
1020
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:P50993}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P50993}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 130..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 287..306; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 319..336; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 770..789; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 800..820; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 841..863; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 916..935; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 949..967; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 983..1003; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins