GPR107
entrez
57720
canonical
uniprot
Q5VW38
canonical
ensembl
ENSG00000148358
resolver
ensp
ENSP00000336988
resolver
ensp
ENSP00000361483
resolver
ensp
ENSP00000361487
resolver
ensp
ENSP00000662490
resolver
enst
ENST00000372410
resolver
genesymbol
GPR107
resolver
genesymbol_syn
KIAA1624
resolver
genesymbol_syn
LUSTR1
resolver
hgnc
HGNC:17830
resolver
uniprot
A0A024R8A3
resolver
uniprot
A6NJ53
resolver
uniprot
G5E994
resolver
uniprot
Q2TB81
resolver
uniprot
Q5JPA3
resolver
uniprot
Q5VW39
resolver
uniprot
Q96T26
resolver
uniprot
Q9H658
resolver
uniprot
Q9HCE8
resolver
uniprot_entry
G5E994_HUMAN
resolver
uniprot_entry
GP107_HUMAN
resolver
uniprot_sec
A0A024R8A3
resolver
uniprot_sec
A6NJ53
resolver
uniprot_sec
Q2TB81
resolver
uniprot_sec
Q5JPA3
resolver
uniprot_sec
Q5VW39
resolver
uniprot_sec
Q96T26
resolver
uniprot_sec
Q9H658
resolver
uniprot_sec
Q9HCE8
resolver
amino_acid_sequence
MAALAPVGSPASRGPRLAAGLRLLPMLGLLQLLAEPGLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNVSSLSLNEPEDKDVTIGFSLDRTKNDGFSSYLDEDVNYCILKKQSVSVTLLILDISRSEVRVKSPPEAGTQLPKIIFSRDEKVLGQSQEPNVNPASAGNQTQKTQDGGKSKRSTVDSKAMGEKSFSVHNNGGAVSFQFFFNISTDDQEGLYSLYFHKCLGKELPSDKFTFSLDIEITEKNPDSYLSAGEIPLPKLYISMAFFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKGDSMGPLQQRANLRAGSRIESHHFAQADLELLASSCPPASVSQRAGITAAINLAKLKLFRHYYVLIVCYIYFTRIIAFLLKLAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEEEDLEMESVVTTSGVMESMKKVKKVTNGSVEPQGEWEGAV
uniprot
proteins
function
FUNCTION: Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (PubMed:22933024). Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity). {ECO:0000250|UniProtKB:D3ZWZ9, ECO:0000269|PubMed:22933024}.; FUNCTION: (Microbial infection) Required for intoxication by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT. May contribute to the retrograde transport of bacterial toxins, including cholera toxin, from the trans-Golgi network to the endoplasmic reticulum. {ECO:0000269|PubMed:25031321}.
uniprot
proteins
mass_dalton
66990
uniprot
proteins
mutagenesis
MUTAGEN 182; /note="R->A: Loss of furin cleavage."; /evidence="ECO:0000269|PubMed:25031321
uniprot
proteins
post_translational_modification
PTM: Cleaved by FURIN to yield two fragments of 17 and 35 kDa that remain associated via a disulfide bond. {ECO:0000269|PubMed:25031321}.
uniprot
proteins
protein_family
LU7TM family
uniprot
proteins
pubmed
10997877
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22933024
uniprot
proteins
pubmed
25031321
uniprot
proteins
sequence_length
600
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:D3ZWZ9}; Multi-pass membrane protein {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:25031321}.
uniprot
proteins
transmembrane_region
TRANSMEM 264..284; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 294..314; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 338..358; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 369..389; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 403..423; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 499..519; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 525..544; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins