Acta1
entrez
29437
canonical
uniprot
P68136
canonical
ensembl
ENSRNOG00000017786
resolver
ensembl
ENSRNOG00055021900
resolver
ensembl
ENSRNOG00060017592
resolver
ensembl
ENSRNOG00065018197
resolver
ensp
ENSRNOP00000024084
resolver
ensp
ENSRNOP00055030646
resolver
ensp
ENSRNOP00060024269
resolver
ensp
ENSRNOP00065024253
resolver
enst
ENSRNOT00000024084
resolver
enst
ENSRNOT00055037573
resolver
enst
ENSRNOT00060030068
resolver
enst
ENSRNOT00065030493
resolver
genesymbol
Acta1
resolver
genesymbol_syn
Acta
resolver
uniprot
P02568
resolver
uniprot
P99020
resolver
uniprot_entry
ACTS_RAT
resolver
uniprot_sec
P02568
resolver
uniprot_sec
P99020
resolver
amino_acid_sequence
MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
uniprot
proteins
mass_dalton
42051
uniprot
proteins
post_translational_modification
PTM: [Actin, alpha skeletal muscle, intermediate form]: N-terminal cleavage of acetylated cysteine of intermediate muscle actin by ACTMAP. {ECO:0000250|UniProtKB:P68134}.; PTM: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization. {ECO:0000250|UniProtKB:P68134}.; PTM: Monomethylation at Lys-86 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. {ECO:0000250|UniProtKB:P68133}.; PTM: Methylated at His-75 by SETD3. {ECO:0000250|UniProtKB:P68133}.
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
6287276
uniprot
proteins
pubmed
6894330
uniprot
proteins
sequence_length
377
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
uniprot
proteins