Wnt signaling pathway
cv_term_accession
KW-0879
canonical
uniprot_keyword
KW-0879
canonical
name
Wnt signaling pathway
uniprot
synonym
Wnt signal transduction pathway
uniprot
synonym
Wnt signaling cascade
uniprot
synonym
Wnt signalling pathway
uniprot
definition
Protein involved in the Wnt signaling pathway. Wnts are a large family of cysteine-rich secreted glycoproteins that control development in organisms ranging from nematodes to mammals. Wnt genes are defined by sequence homology to the original members of the family, Wnt1 in the mouse and wingless (wg) in Drosophila. Wnt signaling is a very complex pathway which includes numerous ligands, receptors and transcriptional effectors. There is a well-characterized canonical pathway as well as diverse, less-characterized noncanonical pathways. Several components of Wnt signaling are implicated in the genesis of human cancer.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords