Klhl7
entrez
52323
canonical
uniprot
Q8BUL5
canonical
ensembl
ENSMUSG00000028986
resolver
ensp
ENSMUSP00000030841
resolver
ensp
ENSMUSP00000129461
resolver
enst
ENSMUST00000030841
resolver
enst
ENSMUST00000163409
resolver
genesymbol
Klhl7
resolver
uniprot
G3UW75
resolver
uniprot
Q9CZP4
resolver
uniprot_entry
G3UW75_MOUSE
resolver
uniprot_entry
KLHL7_MOUSE
resolver
uniprot_sec
Q9CZP4
resolver
amino_acid_sequence
MATSGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILTVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET
uniprot
proteins
function
FUNCTION: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
65938
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
586
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8IXQ5}. Cytoplasm {ECO:0000250|UniProtKB:Q8IXQ5}. Note=Colocalizes with CUL3 in punctate structures at the perinuclear region of the cytoplasm. {ECO:0000250|UniProtKB:Q8IXQ5}.
uniprot
proteins