SPACDR
entrez
402573
canonical
uniprot
Q8IZ16
canonical
ensembl
ENSG00000185955
resolver
ensp
ENSP00000327732
resolver
enst
ENST00000332375
resolver
genesymbol
SPACDR
resolver
genesymbol_syn
C7orf61
resolver
hgnc
HGNC:22135
resolver
uniprot_entry
SACDR_HUMAN
resolver
amino_acid_sequence
MVVVMKFFRWVRRAWQRIISWVFFWRQKIKPTISGHPDSKKHSLKKMEKTLQVVETLRLVELPKEAKPKLGESPELADPCVLAKTTEETEVELGQQGQSLLQLPRTAVKSVSTLMVSALQSGWQMCSWKSSVSSASVSSQVRTQSPLKTPEAELLWEVYLVLWAVRKHLRRLYRRQERHRRHHVRCHAAPRPNPAQSLKLDAQSPL
uniprot
proteins
disease_involvement
DISEASE: Note=A variant causing a frameshift predicted to result in a premature termination codon has been found in a patient with globozoospermia. {ECO:0000269|PubMed:31985809}.
uniprot
proteins
function
FUNCTION: May play a role in acrosome formation and nucleus shaping during spermiogenesis. {ECO:0000269|PubMed:31985809}.
uniprot
proteins
mass_dalton
23862
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23634713
uniprot
proteins
pubmed
31429579
uniprot
proteins
pubmed
31985809
uniprot
proteins
sequence_length
206
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:31429579, ECO:0000269|PubMed:31985809}. Note=Detected in acrosome of round spermatids and spermatozoa. {ECO:0000269|PubMed:31985809}.
uniprot
proteins