Snx21
entrez
101113
canonical
uniprot
Q3UR97
canonical
ensembl
ENSMUSG00000050373
resolver
ensp
ENSMUSP00000054137
resolver
ensp
ENSMUSP00000242555
resolver
enst
ENSMUST00000056181
resolver
genesymbol
Snx21
resolver
uniprot
Q149Q9
resolver
uniprot_entry
Q149Q9_MOUSE
resolver
uniprot_entry
SNX21_MOUSE
resolver
amino_acid_sequence
MASRLLHRLRHALASDGPGEAAAGPEAEQFPESSELEDDDAEGLSSRLSGTLSFTSAEDDPDDEDEDDEAGLDSPPSGDGASGEDAERSPPPDGQRSSQLLARQLQDFWKKSRNTLVPQRLLFEVTSANVVKDPPSKYVLYTLAVMGPGPPDRQPAQISRRYSDFERLHRNLQRQFRGPMSAISFPRKRLRRNFTAETIARRSRAFEQFLGHLQAVPELRQAPDLQDFFVLPELRRAQSLTCTGLYREALALWANAWQLQTQLGTPSGPDRPLLTLAGLAVCHQELEDPGEARACSEKALQLLGDKRPHPFLAPFLEAHVRLSWRLGLDKRQSEAQLQALQEAGLTSTPPPSLKELLIKEVLD
uniprot
proteins
function
FUNCTION: Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)) and phosphatidylinositol 4,5-bisphosphate (PubMed:25882846). May be involved in several stages of intracellular trafficking. {ECO:0000269|PubMed:25882846, ECO:0000305}.
uniprot
proteins
mass_dalton
40308
uniprot
proteins
mutagenesis
MUTAGEN 161; /note="R->Q: Abolishes location on endosome membranes. Abolishes binding to membranes enriched in phosphatidylinositol 3-phosphate. No significant effect on binding to membranes enriched in phosphatidylinositol 4,5-bisphosphate."; /evidence="ECO:0000269|PubMed:25882846
uniprot
proteins
protein_family
Sorting nexin family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
25882846
uniprot
proteins
sequence_length
363
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane {ECO:0000305|PubMed:25882846}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Early endosome membrane {ECO:0000269|PubMed:25882846}; Peripheral membrane protein {ECO:0000269|PubMed:25882846}; Cytoplasmic side {ECO:0000269|PubMed:25882846}.
uniprot
proteins