Fgf8
entrez
14179
canonical
uniprot
P37237
canonical
ensembl
ENSMUSG00000025219
resolver
ensp
ENSMUSP00000026240
resolver
ensp
ENSMUSP00000026241
resolver
ensp
ENSMUSP00000107556
resolver
ensp
ENSMUSP00000107558
resolver
ensp
ENSMUSP00000107559
resolver
enst
ENSMUST00000026240
resolver
enst
ENSMUST00000111925
resolver
genesymbol
Fgf8
resolver
genesymbol_syn
Aigf
resolver
uniprot
D3Z207
resolver
uniprot
F7CLQ4
resolver
uniprot
Q3V279
resolver
uniprot
Q80ZL6
resolver
uniprot_entry
D3Z207_MOUSE
resolver
uniprot_entry
F7CLQ4_MOUSE
resolver
uniprot_entry
FGF8_MOUSE
resolver
uniprot_entry
Q3V279_MOUSE
resolver
uniprot_entry
Q80ZL6_MOUSE
resolver
amino_acid_sequence
MGSPRSALSCLLLHLLVLCLQAQVRSAAQKRGPGAGNPADTLGQGHEDRPFGQRSRAGKNFTNPAPNYPEEGSKEQRDSVLPKVTQRHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
uniprot
proteins
function
FUNCTION: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis (PubMed:7884899). {ECO:0000250|UniProtKB:P55075, ECO:0000269|PubMed:7884899}.
uniprot
proteins
mass_dalton
30420
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
Heparin-binding growth factors family
uniprot
proteins
pubmed
1409588
uniprot
proteins
pubmed
7583127
uniprot
proteins
pubmed
7884899
uniprot
proteins
sequence_length
268
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins