Rps6ka6
entrez
67071
canonical
uniprot
Q7TPS0
canonical
ensembl
ENSMUSG00000025665
resolver
ensp
ENSMUSP00000094073
resolver
ensp
ENSMUSP00000109055
resolver
ensp
ENSMUSP00000115975
resolver
ensp
ENSMUSP00000307704
resolver
enst
ENSMUST00000096348
resolver
enst
ENSMUST00000113428
resolver
enst
ENSMUST00000123951
resolver
genesymbol
Rps6ka6
resolver
uniprot
A2CEE7
resolver
uniprot
B1B0X3
resolver
uniprot
E9PUP0
resolver
uniprot
E9QK39
resolver
uniprot
Q8BWZ2
resolver
uniprot
Q9CUR6
resolver
uniprot_entry
A2CEE7_MOUSE
resolver
uniprot_entry
B1B0X3_MOUSE
resolver
uniprot_entry
E9PUP0_MOUSE
resolver
uniprot_entry
KS6A6_MOUSE
resolver
uniprot_sec
E9QK39
resolver
uniprot_sec
Q8BWZ2
resolver
uniprot_sec
Q9CUR6
resolver
activity_regulation
ACTIVITY REGULATION: Constitutively activated by phosphorylation at Ser-252, Ser-392, and Ser-409 in serum-starved cells. Does not require growth factor stimulation for significant kinase activity (By similarity). {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MLPFAPVEDPWDQEDMEVFGSTSSSEPQVVFTMKNAATVMREHERKEVNDLKMVDEPMEEGEPVSCRREELVKEVPITQHVKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRAHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTFCFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPVTSSNVLPIVQINGNAAQFSEAYELKEDIGIGSYSVCKRCIHSASNVEFAVKIIDKNKRDPSEEIEILMRYGQHPNIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCFSEQEASNVLYVITKTVECLHSQGVVHRDLKPSNILYMDESAHPDSIKICDFGFAKQLRGENGLLLTPCYTANFVAPEVLTQQGYDAACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRGAKDLLSHMLHMDPHQRYTAEQVLKHPWITQREQLPRHQPNSDEPPQEAVAAPYSVLARNPNRHHPILEPVTASRLAQRRNMKKRTSTGL
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. {ECO:0000269|PubMed:15121846}.
uniprot
proteins
mass_dalton
86571
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at Ser-252, Ser-392, and Ser-409 in serum-starved cells. {ECO:0000250}.
uniprot
proteins
protein_family
AGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
S6 kinase subfamily
uniprot
proteins
pubmed
15121846
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
764
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol. Nucleus. Note=Predominantly cytosolic. {ECO:0000250}.
uniprot
proteins