Coa3
entrez
52469
canonical
uniprot
Q9D2R6
canonical
ensembl
ENSMUSG00000017188
resolver
ensp
ENSMUSP00000017332
resolver
enst
ENSMUST00000017332
resolver
genesymbol
Coa3
resolver
genesymbol_syn
Ccdc56
resolver
uniprot
A2A4J6
resolver
uniprot_entry
COA3_MOUSE
resolver
uniprot_sec
A2A4J6
resolver
amino_acid_sequence
MAAPGAGDPLNAKNGNAPFAQRIDPSREKLTPAQLQFMRQVQLAQWQKTLPQRRTRNIMTGLGIGALVLAIYGYTFYSVAQERFLDELEDEAKAARARALERERASGP
uniprot
proteins
function
FUNCTION: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly. {ECO:0000250|UniProtKB:Q9Y2R0}.
uniprot
proteins
mass_dalton
11987
uniprot
proteins
protein_family
COA3 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
108
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 58..80; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins