LOXL4
entrez
84171
canonical
uniprot
Q96JB6
canonical
ensembl
ENSG00000138131
resolver
ensp
ENSP00000260702
resolver
ensp
ENSP00000575937
resolver
ensp
ENSP00000575938
resolver
ensp
ENSP00000575939
resolver
ensp
ENSP00000575945
resolver
ensp
ENSP00000575946
resolver
ensp
ENSP00000628295
resolver
enst
ENST00000260702
resolver
enst
ENST00000905878
resolver
enst
ENST00000905886
resolver
enst
ENST00000905887
resolver
enst
ENST00000958236
resolver
genesymbol
LOXL4
resolver
genesymbol_syn
LOXC
resolver
hgnc
HGNC:17171
resolver
uniprot
Q5W0B3
resolver
uniprot
Q96DY1
resolver
uniprot
Q96PC0
resolver
uniprot
Q9H6T5
resolver
uniprot_entry
LOXL4_HUMAN
resolver
uniprot_sec
Q5W0B3
resolver
uniprot_sec
Q96DY1
resolver
uniprot_sec
Q96PC0
resolver
uniprot_sec
Q9H6T5
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by beta-aminopropionitrile (BAPN). {ECO:0000269|PubMed:14551188}.
uniprot
proteins
amino_acid_sequence
MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
uniprot
proteins
ec_number
1.4.3.13
uniprot
proteins
function
FUNCTION: Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers. {ECO:0000269|PubMed:14551188}.
uniprot
proteins
mass_dalton
84483
uniprot
proteins
post_translational_modification
PTM: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine. {ECO:0000250|UniProtKB:P33072}.; PTM: May be proteolytically cleaved by BMP1. {ECO:0000305|PubMed:14551188}.
uniprot
proteins
protein_family
Lysyl oxidase family
uniprot
proteins
pubmed
11292829
uniprot
proteins
pubmed
11691588
uniprot
proteins
pubmed
11691589
uniprot
proteins
pubmed
14551188
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
756
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000305}.
uniprot
proteins