Eqtn
entrez
67753
canonical
uniprot
Q9D9V2
canonical
ensembl
ENSMUSG00000028575
resolver
ensp
ENSMUSP00000030309
resolver
ensp
ENSMUSP00000102714
resolver
genesymbol
Eqtn
resolver
genesymbol_syn
Afaf
resolver
genesymbol_syn
Mn9
resolver
uniprot
A2AJE0
resolver
uniprot
Q2LCV5
resolver
uniprot
Q5FWB0
resolver
uniprot_entry
EQTN_MOUSE
resolver
uniprot_sec
A2AJE0
resolver
uniprot_sec
Q2LCV5
resolver
uniprot_sec
Q5FWB0
resolver
amino_acid_sequence
MDFILLIILSGVFLPDIISLQPIVGQEPGVTLSDEEQYYADEENNTDGNSVALHKLEENEMDTPANEKTGNYYKDIKQYVFTTPNIKGSEVSVTATTNLEFAVKKNYKASKPTASGEEEKPSESSRKTSTPNIPAFWTILSKAVNETAVSMDDKDQFFQPIPASDLNATNEDKLSELEEIKLKLMLGISLMTLVLLIPLLIFCFATLYKLRHLRDKSYESQYSINPELATLSYFHPTEGVSDTSFSKSADSNSYWVHNSSEMRRSRTRRSKSKPMDFSAGSNQTVLTDESSFLPPEETRFLLPEEPGKELIVERGPMQAMNEIDAQLLLNKEGSPSN
uniprot
proteins
function
FUNCTION: Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. {ECO:0000269|PubMed:16831425, ECO:0000269|PubMed:19285662, ECO:0000269|PubMed:9674989}.
uniprot
proteins
mass_dalton
37764
uniprot
proteins
mutagenesis
MUTAGEN 128; /note="T->A: Does not affect MN9 antibody detectability."; /evidence="ECO:0000269|PubMed:19605790"; MUTAGEN 129; /note="S->A: Does not affect MN9 antibody detectability."; /evidence="ECO:0000269|PubMed:19605790"; MUTAGEN 130; /note="T->A: Does not affect MN9 antibody detectability."; /evidence="ECO:0000269|PubMed:19605790"; MUTAGEN 138; /note="T->A: MN9 antibody detectability is lost."; /evidence="ECO:0000269|PubMed:19605790"; MUTAGEN 141; /note="S->A: Does not affect MN9 antibody detectability."; /evidence="ECO:0000269|PubMed:19605790
uniprot
proteins
post_translational_modification
PTM: Highly N- and O-glycosylated; contains sialic acid. MN9 epitope is O-glycosylated. {ECO:0000269|PubMed:19605790}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16831425
uniprot
proteins
pubmed
19285662
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19605790
uniprot
proteins
pubmed
9674989
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane; Single-pass type I membrane protein. Note=In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm.
uniprot
proteins
transmembrane_region
TRANSMEM 184..204; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins