Coq9
entrez
498909
canonical
uniprot
Q68FT1
canonical
ensembl
ENSRNOG00000016190
resolver
ensembl
ENSRNOG00055022087
resolver
ensembl
ENSRNOG00060015964
resolver
ensembl
ENSRNOG00065003634
resolver
ensp
ENSRNOP00000021716
resolver
ensp
ENSRNOP00055031013
resolver
ensp
ENSRNOP00060021927
resolver
ensp
ENSRNOP00065003795
resolver
enst
ENSRNOT00000021716
resolver
enst
ENSRNOT00055037977
resolver
enst
ENSRNOT00060027333
resolver
enst
ENSRNOT00065005263
resolver
genesymbol
Coq9
resolver
uniprot
A1L109
resolver
uniprot_entry
COQ9_RAT
resolver
uniprot_sec
A1L109
resolver
amino_acid_sequence
MAATAAVSGVLRRLGWRLLQLRCLPVARCQSPLMPRAFHTAVGFRSSEEQRQQPPHSSQQHSETQGPEFSRPPPRYTDQSGEEEEDYESEEQIQHRILTAALEFVPDHGWTAEAIAEGAQSLGLSSAAASMFGSDGSELILHFVTQCNARLNHVLEEEQKLVQLGQAEKRKTDQFLRDAVETRLRMLIPYIEHWPRALSILLLPQNIPPSLSLLTSMVDDMWHYAGDQSTDFNWYTRRAVLAGIYNTTELVMMQDSSPDFEDTWRFLDNRINDAMNMGHTAKQVKSTGEALVQGLMGAAVTLKNLTGLNQRR
uniprot
proteins
function
FUNCTION: Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to COQ7, therefore facilitating the COQ7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. {ECO:0000250|UniProtKB:O75208}.
uniprot
proteins
mass_dalton
35146
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000250|UniProtKB:Q8K1Z0}.
uniprot
proteins
post_translational_modification
PTM: In response to mitochondrial stress, the precursor protein is ubiquitinated by the SIFI complex in the cytoplasm before mitochondrial import, leading to its degradation. Within the SIFI complex, UBR4 initiates ubiquitin chain that are further elongated or branched by KCMF1. {ECO:0000250|UniProtKB:O75208}.
uniprot
proteins
protein_family
COQ9 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
312
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q8K1Z0}. Note=Associates with cardiolipin-rich membranes which leads to the lipid bilayer deformation and then accessing to membrane-bound lipids. {ECO:0000250|UniProtKB:O75208}.
uniprot
proteins