TRMT11
entrez
60487
canonical
uniprot
Q7Z4G4
canonical
ensembl
ENSG00000066651
resolver
ensp
ENSP00000333934
resolver
genesymbol
TRMT11
resolver
genesymbol_syn
C6orf75
resolver
hgnc
HGNC:21080
resolver
uniprot
E1P570
resolver
uniprot
Q5JY11
resolver
uniprot
Q6PGQ5
resolver
uniprot
Q9HC13
resolver
uniprot_entry
TRM11_HUMAN
resolver
uniprot_sec
E1P570
resolver
uniprot_sec
Q5JY11
resolver
uniprot_sec
Q6PGQ5
resolver
uniprot_sec
Q9HC13
resolver
amino_acid_sequence
MALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKSPFWILSIPSEDIARNLMKRTVCAKSIFELWGHGQSPEELYSSLKNYPVEKMVPFLHSDSTYKIKIHTFNKTLTQEEKIKRIDALEFLPFEGKVNLKKPQHVFSVLEDYGLDPNCIPENPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMANHGKVKENDIVFDPFVGTGGLLIACAHFGAYVYGTDIDYNTVHGLGKATRKNQKWRGPDENIRANLRQYGLEKYYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRTGSQKEIPKGIEKWEKCPESHVPVSLSYHLSDMFLDLLNFAAETLVLGGRLVYWLPVYTPEYTEEMVPWHPCLELVSNCEQKLSSHTSRRLITMEKVKKFENRDQYSHLLSDHFLPYQGHNSFREKYFSGVTKRIAKEEKSTQE
uniprot
proteins
ec_number
2.1.1.214
uniprot
proteins
function
FUNCTION: Catalytic subunit of the TRMT11-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 10 (m2G10) in tRNAs (PubMed:37283053). This is one of the major tRNA (guanine-N(2))-methyltransferases (PubMed:37283053). {ECO:0000269|PubMed:37283053}.
uniprot
proteins
mass_dalton
53421
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
TRM11 methyltransferase family
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
34948388
uniprot
proteins
pubmed
37283053
uniprot
proteins
sequence_length
463
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:34948388}.
uniprot
proteins