Spaca3
entrez
75622
canonical
uniprot
Q9D9X8
canonical
ensembl
ENSMUSG00000053184
resolver
ensp
ENSMUSP00000099511
resolver
ensp
ENSMUSP00000099512
resolver
genesymbol
Spaca3
resolver
genesymbol_syn
Lyc3
resolver
genesymbol_syn
Lyzl3
resolver
genesymbol_syn
Sllp1
resolver
uniprot
Q5SUU3
resolver
uniprot
Q6PKP1
resolver
uniprot
Q6PX67
resolver
uniprot_entry
SACA3_MOUSE
resolver
uniprot_sec
Q5SUU3
resolver
uniprot_sec
Q6PKP1
resolver
uniprot_sec
Q6PX67
resolver
amino_acid_sequence
MGICMSMYTQVLVPVDADGDHHILWSRFYERWGSCFNPCAGLVNCLPPHSSALYLCHRMEARSRAPRRQLCPPGITWLALAYLLSCLLASSKAKVFSRCELAKEMHDFGLDGYRGYNLADWVCLAYYTSGFNTNAVDHEADGSTNNGIFQISSRRWCRTLASNGPNLCRIYCTDLLNNDLKDSIVCAMKIVQEPLGLGYWEAWRHHCQGRDLSDWVDGCDF
uniprot
proteins
function
FUNCTION: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity). {ECO:0000250, ECO:0000269|PubMed:15982649}.
uniprot
proteins
mass_dalton
25020
uniprot
proteins
protein_family
Glycosyl hydrolase 22 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15982649
uniprot
proteins
pubmed
16014814
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22206759
uniprot
proteins
sequence_length
221
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000305|PubMed:15982649}; Single-pass type II membrane protein {ECO:0000305|PubMed:15982649}. Note=Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 70..90; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins