TXNRD3
entrez
114112
canonical
uniprot
Q86VQ6
canonical
ensembl
ENSG00000197763
resolver
ensp
ENSP00000429584
resolver
ensp
ENSP00000430031
resolver
enst
ENST00000524230
resolver
genesymbol
TXNRD3
resolver
genesymbol_syn
TGR
resolver
genesymbol_syn
TRXR3
resolver
genesymbol_syn
TXNRD3IT1
resolver
genesymbol_syn
TXNRD3NB
resolver
hgnc
HGNC:20667
resolver
uniprot
B4DRZ5
resolver
uniprot
Q6F5E7
resolver
uniprot
Q6PIS8
resolver
uniprot
Q9NNW6
resolver
uniprot
Q9P101
resolver
uniprot_entry
B4DRZ5_HUMAN
resolver
uniprot_entry
TRXR3_HUMAN
resolver
uniprot_sec
Q6F5E7
resolver
uniprot_sec
Q6PIS8
resolver
uniprot_sec
Q9NNW6
resolver
uniprot_sec
Q9P101
resolver
amino_acid_sequence
MERSPPQSPGPGKAGDAPNRRSGHVRGARVLSPPGRRARLSSPGPSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHSTRVKELFSSLGVECNVLELDQVDDGARVQEVLSEITNQKTVPNIFVNKVHVGGCDQTFQAYQSGLLQKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG
uniprot
proteins
ec_number
1.8.1.9
uniprot
proteins
function
FUNCTION: Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity). {ECO:0000250|UniProtKB:Q99MD6}.
uniprot
proteins
mass_dalton
70683
uniprot
proteins
protein_family
Class-I pyridine nucleotide-disulfide oxidoreductase family
uniprot
proteins
pubmed
10455115
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15674732
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20018845
uniprot
proteins
sequence_length
643
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q99MD6}. Nucleus {ECO:0000250|UniProtKB:Q99MD6}. Microsome {ECO:0000250|UniProtKB:Q99MD6}. Endoplasmic reticulum {ECO:0000250}. Note=Detected in cytoplasm and nucleus in late spermatids. {ECO:0000250|UniProtKB:Q99MD6}.
uniprot
proteins