Ccnb1
entrez
25203
canonical
uniprot
P30277
canonical
ensembl
ENSRNOG00000058539
resolver
ensembl
ENSRNOG00055027308
resolver
ensembl
ENSRNOG00060029363
resolver
ensembl
ENSRNOG00065022767
resolver
ensp
ENSRNOP00000082369
resolver
ensp
ENSRNOP00055038891
resolver
ensp
ENSRNOP00060042457
resolver
ensp
ENSRNOP00065031554
resolver
enst
ENSRNOT00000104772
resolver
enst
ENSRNOT00055047311
resolver
enst
ENSRNOT00060051036
resolver
enst
ENSRNOT00065038897
resolver
genesymbol
Ccnb1
resolver
uniprot_entry
CCNB1_RAT
resolver
amino_acid_sequence
MALRVTRNTKINTENKAKVSMAGAKRVPVAVAASKPLLRSRTALGDIGNKVSEQSRIPLKKETKKLGSGTVTVKALPKPVDKVPVCEPEVELDEPEPEPVMEVKHSPEPILVDTPSPSPMETSGCAPAEEYLCQAFSDVILAVSDVDADDGGDPNLCSEYVKDIYAYLRQLEEEQSVRPKYLLGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDSCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILDNGEWTPTLQHYLSHTEESLLPVMQHLAKNIVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNCTLVQNLSKAVTKA
uniprot
proteins
function
FUNCTION: Essential for the control of the cell cycle at the G2/M (mitosis) transition (By similarity). Binds and activates cyclin-dependent protein kinase CDK1/CDC2 (By similarity). {ECO:0000250|UniProtKB:P14635}.
uniprot
proteins
mass_dalton
47391
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Deubiquitinated by USP22 during G2/M phase (By similarity). {ECO:0000250}.; PTM: Phosphorylated by PLK1 at Ser-123 on centrosomes during prophase: phosphorylation by PLK1 does not cause nuclear import. Phosphorylation at Ser-137 was also reported to be mediated by PLK1 but Ser-123 seems to be the primary phosphorylation site (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Cyclin AB subfamily
uniprot
proteins
protein_family
Cyclin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8123599
uniprot
proteins
pubmed
8270434
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
uniprot
proteins