Slc6a13
entrez
171163
canonical
uniprot
P31646
canonical
ensembl
ENSRNOG00000012876
resolver
ensembl
ENSRNOG00055011300
resolver
ensembl
ENSRNOG00060027841
resolver
ensembl
ENSRNOG00065029674
resolver
ensp
ENSRNOP00000071638
resolver
ensp
ENSRNOP00055015420
resolver
ensp
ENSRNOP00060040263
resolver
ensp
ENSRNOP00065042206
resolver
enst
ENSRNOT00000079744
resolver
enst
ENSRNOT00055019145
resolver
enst
ENSRNOT00060048347
resolver
enst
ENSRNOT00065051267
resolver
genesymbol
Slc6a13
resolver
genesymbol_syn
Gabt2
resolver
genesymbol_syn
Gat-2
resolver
uniprot
A0A0G2K0Z3
resolver
uniprot_entry
A0A0G2K0Z3_RAT
resolver
uniprot_entry
S6A13_RAT
resolver
activity_regulation
ACTIVITY REGULATION: GABA transport is inhibited by beta-alanine, L-2,4-Diaminobutyric acid, hypotaurine and nipecotic acid (PubMed:1400419, PubMed:22896705). Taurine transport is inhibited by hypotaurine, beta-alanine and nipecotic acid (PubMed:22896705). {ECO:0000269|PubMed:1400419, ECO:0000269|PubMed:22896705}.
uniprot
proteins
amino_acid_sequence
MDNRVSGTTSNGETKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQKTNNSLNVTSENATSPVIEFWERRVLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCILNSSTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREILILIVSVVSFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKPWPLIKYCWLFFTPAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSIYKLRTLKGPLRERLRQLVCPAEDLPQKSQPELTSPATPMTSLLRLTELESNC
uniprot
proteins
function
FUNCTION: Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:1400419, PubMed:22896705). Mediates transport of taurine and is the major taurine transporter in hepatocytes (PubMed:22896705). Can also mediate transport of beta-alanine and hypotaurine (By similarity). {ECO:0000250|UniProtKB:P31649, ECO:0000269|PubMed:1400419, ECO:0000269|PubMed:22896705}.
uniprot
proteins
mass_dalton
68263
uniprot
proteins
protein_family
SLC6A13 subfamily
uniprot
proteins
protein_family
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family
uniprot
proteins
pubmed
1400419
uniprot
proteins
pubmed
22896705
uniprot
proteins
sequence_length
602
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:22896705}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:P31649}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 41..61; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 121..141; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 207..227; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 233..253; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 282..302; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 319..339; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 366..386; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 418..438; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 453..473; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 490..510; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 528..548; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins