Cd2
entrez
12481
canonical
uniprot
P08920
canonical
ensembl
ENSMUSG00000027863
resolver
ensp
ENSMUSP00000029456
resolver
enst
ENSMUST00000029456
resolver
genesymbol
Cd2
resolver
genesymbol_syn
Ly-37
resolver
uniprot
Q549Q4
resolver
uniprot
Q61394
resolver
uniprot_entry
CD2_MOUSE
resolver
uniprot_entry
Q549Q4_MOUSE
resolver
uniprot_sec
Q61394
resolver
amino_acid_sequence
MKCKFLGSFFLLFSLSGKGADCRDNETIWGVLGHGITLNIPNFQMTDDIDEVRWVRRGTLVAEFKRKKPPFLISETYEVLANGSLKIKKPMMRNDSGTYNVMVYGTNGMTRLEKDLDVRILERVSKPMIHWECPNTTLTCAVLQGTDFELKLYQGETLLNSLPQKNMSYQWTNLNAPFKCEAINPVSKESKMEVVNCPEKGLSFYVTVGVGAGGLLLVLLVALFIFCICKRRKRNRRRKDEELEIKASRTSTVERGPKPHSTPAAAAQNSVALQAPPPPGHHLQTPGHRPLPPGHRTREHQQKKRPPPSGTQIHQQKGPPLPRPRVQPKPPCGSGDGVSLPPPN
uniprot
proteins
function
FUNCTION: CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
uniprot
proteins
mass_dalton
38415
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:2440689}.
uniprot
proteins
pubmed
12530983
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2440689
uniprot
proteins
pubmed
2820751
uniprot
proteins
pubmed
2894031
uniprot
proteins
pubmed
3257775
uniprot
proteins
pubmed
9741631
uniprot
proteins
sequence_length
344
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:2440689}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 204..229; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins