IL1F10
entrez
84639
canonical
uniprot
Q8WWZ1
canonical
ensembl
ENSG00000136697
resolver
ensp
ENSP00000341794
resolver
ensp
ENSP00000376893
resolver
genesymbol
IL1F10
resolver
genesymbol_syn
FIL1T
resolver
genesymbol_syn
IL1HY2
resolver
genesymbol_syn
IL38
resolver
hgnc
HGNC:15552
resolver
uniprot
Q53SR9
resolver
uniprot
Q56AT8
resolver
uniprot
Q7RTZ5
resolver
uniprot
Q969H5
resolver
uniprot
Q9BYX1
resolver
uniprot_entry
IL1FA_HUMAN
resolver
uniprot_sec
Q53SR9
resolver
uniprot_sec
Q56AT8
resolver
uniprot_sec
Q7RTZ5
resolver
uniprot_sec
Q969H5
resolver
uniprot_sec
Q9BYX1
resolver
amino_acid_sequence
MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCCAEKICILPNRGLARTKVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPGWFLCGPAEPQQPVQLTKESEPSARTKFYFEQSW
uniprot
proteins
function
FUNCTION: Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. {ECO:0000269|PubMed:22315422}.
uniprot
proteins
mass_dalton
16943
uniprot
proteins
protein_family
IL-1 family
uniprot
proteins
pubmed
11278614
uniprot
proteins
pubmed
11747621
uniprot
proteins
pubmed
11991722
uniprot
proteins
pubmed
11991723
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
22315422
uniprot
proteins
pubmed
32272059
uniprot
proteins
sequence_length
152
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:32272059}. Secreted {ECO:0000269|PubMed:32272059}. Note=The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. {ECO:0000269|PubMed:32272059}.
uniprot
proteins