MGAT5B
entrez
146664
canonical
uniprot
Q3V5L5
canonical
ensembl
ENSG00000167889
resolver
ensp
ENSP00000301618
resolver
ensp
ENSP00000391227
resolver
ensp
ENSP00000456037
resolver
ensp
ENSP00000698641
resolver
genesymbol
MGAT5B
resolver
genesymbol_syn
KIAA2008
resolver
hgnc
HGNC:24140
resolver
uniprot
Q6P3S8
resolver
uniprot
Q6P6B3
resolver
uniprot
Q766X5
resolver
uniprot
Q76D04
resolver
uniprot
Q96LS2
resolver
uniprot_entry
MGT5B_HUMAN
resolver
uniprot_sec
Q6P3S8
resolver
uniprot_sec
Q6P6B3
resolver
uniprot_sec
Q766X5
resolver
uniprot_sec
Q76D04
resolver
uniprot_sec
Q96LS2
resolver
amino_acid_sequence
MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALARLENSSELHRAGGDLHFPADRMPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAQRAPKPLPKVQAVFRSNLSHLLDLMGSGKESLIFMKKRTKRLTAQWALAAQRLAQKLGATQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILTALYVLGHGLRVTVSLKELQSNLGVPPGRGSCPLTMPLPFDLIYTDYHGLQQMKRHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKRLIKGGKASNMAVVYGKEASIWKLQGKEKFLGILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMRTQVDPYLPYEYTCEGMLERIHAYIQHQDFCRAPDPALPEAHAPQSPFVLAPNATHLEWARNTSLAPGAWPPAHALRAWLAVPGRACTDTCLDHGLICEPSFFPFLNSQDAFLKLQVPCDSTESEMNHLYPAFAQPGQECYLQKEPLLFSCAGSNTKYRRLCPCRDFRKGQVALCQGCL
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
ec_number
2.4.1.155
uniprot
proteins
function
FUNCTION: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. {ECO:0000269|PubMed:12941944, ECO:0000269|PubMed:14617637, ECO:0000269|PubMed:14623122, ECO:0000269|PubMed:16606368, ECO:0000269|PubMed:16857188, ECO:0000269|PubMed:19846580}.
uniprot
proteins
mass_dalton
89535
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000269|PubMed:12941944, ECO:0000269|PubMed:14617637, ECO:0000269|PubMed:14623122, ECO:0000269|PubMed:19846580}.
uniprot
proteins
protein_family
Glycosyltransferase 18 family
uniprot
proteins
pubmed
12941944
uniprot
proteins
pubmed
14617637
uniprot
proteins
pubmed
14623122
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16606368
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
16857188
uniprot
proteins
pubmed
19846580
uniprot
proteins
sequence_length
792
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q765H6}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q765H6}.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins