M6PR
entrez
4074
canonical
uniprot
P20645
canonical
ensembl
ENSG00000003056
resolver
ensp
ENSP00000000412
resolver
ensp
ENSP00000437595
resolver
ensp
ENSP00000440488
resolver
ensp
ENSP00000561614
resolver
ensp
ENSP00000561615
resolver
ensp
ENSP00000561616
resolver
ensp
ENSP00000561617
resolver
ensp
ENSP00000606931
resolver
ensp
ENSP00000611122
resolver
ensp
ENSP00000611124
resolver
enst
ENST00000000412
resolver
enst
ENST00000536844
resolver
enst
ENST00000891555
resolver
enst
ENST00000891556
resolver
enst
ENST00000891557
resolver
enst
ENST00000891558
resolver
enst
ENST00000936872
resolver
enst
ENST00000941063
resolver
enst
ENST00000941065
resolver
genesymbol
M6PR
resolver
genesymbol_syn
MPR46
resolver
genesymbol_syn
MPRD
resolver
hgnc
HGNC:6752
resolver
uniprot
A8K528
resolver
uniprot
D3DUV5
resolver
uniprot
F5GX30
resolver
uniprot_entry
F5GX30_HUMAN
resolver
uniprot_entry
MPRD_HUMAN
resolver
uniprot_sec
A8K528
resolver
uniprot_sec
D3DUV5
resolver
amino_acid_sequence
MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
uniprot
proteins
function
FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
uniprot
proteins
mass_dalton
30993
uniprot
proteins
pubmed
11387475
uniprot
proteins
pubmed
11886874
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1849818
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2441386
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
277
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 186..210; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins