Get1
entrez
288233
canonical
uniprot
Q6P6S5
canonical
ensembl
ENSRNOG00000001629
resolver
ensembl
ENSRNOG00055016718
resolver
ensembl
ENSRNOG00060020812
resolver
ensembl
ENSRNOG00065013811
resolver
ensp
ENSRNOP00000002222
resolver
ensp
ENSRNOP00055022879
resolver
ensp
ENSRNOP00060029790
resolver
ensp
ENSRNOP00065017632
resolver
enst
ENSRNOT00000002222
resolver
enst
ENSRNOT00055028429
resolver
enst
ENSRNOT00060036222
resolver
enst
ENSRNOT00065022736
resolver
genesymbol
Get1
resolver
genesymbol_syn
Wrb
resolver
uniprot_entry
GET1_RAT
resolver
amino_acid_sequence
MSASETDRWAWLLVLCFVFGCNVLRILLPTLSSFISRVLQKDAEQESQMRAEIQSMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWFISVAFYVLQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGIGVTCWILVCNKVVAIILHPFS
uniprot
proteins
function
FUNCTION: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (PubMed:23041287). Together with CAMLG/GET2, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (PubMed:23041287). Required to ensure correct topology and ER insertion of CAMLG (By similarity). {ECO:0000250|UniProtKB:O00258, ECO:0000269|PubMed:23041287}.
uniprot
proteins
mass_dalton
19899
uniprot
proteins
protein_family
WRB/GET1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23041287
uniprot
proteins
sequence_length
174
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O00258}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 149..169; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins