Ppp2r3c
entrez
59032
canonical
uniprot
Q9JK24
canonical
ensembl
ENSMUSG00000021022
resolver
ensp
ENSMUSP00000021410
resolver
ensp
ENSMUSP00000339060
resolver
enst
ENSMUST00000021410
resolver
genesymbol
Ppp2r3c
resolver
genesymbol_syn
G5pr
resolver
uniprot
B2RR97
resolver
uniprot
Q9CSA6
resolver
uniprot
Q9JJD2
resolver
uniprot_entry
P2R3C_MOUSE
resolver
uniprot_sec
B2RR97
resolver
uniprot_sec
Q9CSA6
resolver
uniprot_sec
Q9JJD2
resolver
amino_acid_sequence
MDWKDVLRRRLASPNTDPKRKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPMIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNENSADLDDT
uniprot
proteins
function
FUNCTION: May regulate MCM3AP phosphorylation through phosphatase recruitment (PubMed:12167160). May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex (By similarity). May play a role in the activation-induced cell death of B-cells (PubMed:16129705, PubMed:16343422). {ECO:0000250|UniProtKB:Q969Q6, ECO:0000269|PubMed:12167160, ECO:0000269|PubMed:16129705, ECO:0000269|PubMed:16343422}.
uniprot
proteins
mass_dalton
53407
uniprot
proteins
pubmed
12167160
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15820313
uniprot
proteins
pubmed
16129705
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16343422
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12167160}. Cytoplasm {ECO:0000269|PubMed:12167160}. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis.
uniprot
proteins