Amigo2
entrez
105827
canonical
uniprot
Q80ZD9
canonical
ensembl
ENSMUSG00000048218
resolver
ensp
ENSMUSP00000059913
resolver
ensp
ENSMUSP00000155019
resolver
enst
ENSMUST00000053106
resolver
enst
ENSMUST00000229890
resolver
genesymbol
Amigo2
resolver
genesymbol_syn
Ali1
resolver
uniprot
Q4VBE6
resolver
uniprot_entry
AMGO2_MOUSE
resolver
uniprot_entry
Q4VBE6_MOUSE
resolver
amino_acid_sequence
MSLRFHTLPTLPRAVKPGCRELLCLLVIAVMVSPSASGMCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDADWIPVSFVKLSTLILRHNNITSISTGSFSTTPNLKCLDLSSNRLKSVKSATFQELKALEVLLLYNNHISYLDPAAFGGLSHLQKLYLSGNFLTQFPMDLYTGRFKLADLTFLDVSYNRIPSIPMHHINLVPGRQLRGIYLHGNPFVCDCSLYSLLIFWYRRHFSSVMDFKNDYTCRLWSDSRHSHQLQLLQESFLNCSYSVINGSFHALGFIHEAQVGERAIVHCDSKTGNGNTDFIWVGPDNRLLEPDKDMGNFRVFYNGSLVIENPGFEDAGVYSCIAMNRQRLLNETVDIMINVSNFTINRSHAHEAFNTAFTTLAACVASIVLVLLYLYLTPCPCKCKAKRQKNTLSQSSAHSSILSPGPTGDASADDRKAGKRVVFLEPLKDTAAGQNGKVKLFPSETVIAEGILKSTRAKSDSDSVNSVFSDTPFVAST
uniprot
proteins
function
FUNCTION: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
57562
uniprot
proteins
protein_family
AMIGO family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12629050
uniprot
proteins
pubmed
12843293
uniprot
proteins
sequence_length
519
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 398..418; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins