Rhobtb2
entrez
246710
canonical
uniprot
Q91V93
canonical
ensembl
ENSMUSG00000022075
resolver
ensp
ENSMUSP00000022665
resolver
ensp
ENSMUSP00000316419
resolver
enst
ENSMUST00000022665
resolver
genesymbol
Rhobtb2
resolver
genesymbol_syn
Dbc2
resolver
uniprot
Q8BYU3
resolver
uniprot
Q8K1A8
resolver
uniprot_entry
RHBT2_MOUSE
resolver
uniprot_sec
Q8BYU3
resolver
uniprot_sec
Q8K1A8
resolver
amino_acid_sequence
MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSGSGGPRPEDHRSHPEQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTFKSRLMVVVKMDNSIQPGPFRAVLKYLYTGELGENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIVLANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLRRQPKRRWLFWNSPSSPSSSAAGSASPSSSSSAVV
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Regulator of cell proliferation and apoptosis. It likely functions as a substrate-adapter that recruits key substrates, e.g. MSI2, to CUL3-based ubiquitin ligase complexes for degradation. Required for MSI2 ubiquitination and degradation. {ECO:0000250|UniProtKB:Q9BYZ6}.
uniprot
proteins
mass_dalton
82650
uniprot
proteins
post_translational_modification
PTM: Autoubiquitinated by RHOBTB2-CUL3-RBX1 ubiquitin ligase complex. {ECO:0000250|UniProtKB:Q9BYZ6}.
uniprot
proteins
protein_family
Rho family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
12370419
uniprot
proteins
pubmed
12426103
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
728
uniprot
proteins