TCEA1
entrez
6917
canonical
uniprot
P23193
canonical
ensembl
ENSG00000187735
resolver
ensp
ENSP00000395483
resolver
ensp
ENSP00000428426
resolver
genesymbol
TCEA1
resolver
genesymbol_syn
GTF2S
resolver
genesymbol_syn
TFIIS
resolver
hgnc
HGNC:11612
resolver
uniprot
A0A384MTX4
resolver
uniprot
A6NF25
resolver
uniprot
A8K339
resolver
uniprot
B7Z4W0
resolver
uniprot
Q15563
resolver
uniprot
Q6FG87
resolver
uniprot_entry
A0A384MTX4_HUMAN
resolver
uniprot_entry
B7Z4W0_HUMAN
resolver
uniprot_entry
TCEA1_HUMAN
resolver
uniprot_sec
A6NF25
resolver
uniprot_sec
A8K339
resolver
uniprot_sec
Q15563
resolver
uniprot_sec
Q6FG87
resolver
amino_acid_sequence
MEDEVVRFAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
uniprot
proteins
disease_involvement
DISEASE: Note=A chromosomal aberration involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1. {ECO:0000269|PubMed:10029085}.
uniprot
proteins
function
FUNCTION: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
uniprot
proteins
mass_dalton
33970
uniprot
proteins
protein_family
TFS-II family
uniprot
proteins
pubmed
10029085
uniprot
proteins
pubmed
1378807
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
1708494
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19367720
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21127351
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
27193682
uniprot
proteins
pubmed
7626141
uniprot
proteins
pubmed
8112616
uniprot
proteins
sequence_length
301
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins