DMTF1
entrez
9988
canonical
uniprot
Q9Y222
canonical
ensembl
ENSG00000135164
resolver
ensp
ENSP00000332171
resolver
ensp
ENSP00000378193
resolver
ensp
ENSP00000412532
resolver
ensp
ENSP00000542111
resolver
ensp
ENSP00000542112
resolver
ensp
ENSP00000542113
resolver
ensp
ENSP00000601142
resolver
ensp
ENSP00000601143
resolver
ensp
ENSP00000623586
resolver
ensp
ENSP00000623587
resolver
ensp
ENSP00000623589
resolver
ensp
ENSP00000664265
resolver
genesymbol
DMTF1
resolver
genesymbol_syn
DMP1
resolver
hgnc
HGNC:14603
resolver
uniprot
B2RBE1
resolver
uniprot
B3KMJ8
resolver
uniprot
B4DJS5
resolver
uniprot
Q05C48
resolver
uniprot
Q59G79
resolver
uniprot
Q6IS13
resolver
uniprot
Q969T2
resolver
uniprot
Q9H2Z2
resolver
uniprot
Q9H2Z3
resolver
uniprot_entry
B3KMJ8_HUMAN
resolver
uniprot_entry
DMTF1_HUMAN
resolver
uniprot_sec
B2RBE1
resolver
uniprot_sec
B4DJS5
resolver
uniprot_sec
Q05C48
resolver
uniprot_sec
Q59G79
resolver
uniprot_sec
Q6IS13
resolver
uniprot_sec
Q969T2
resolver
uniprot_sec
Q9H2Z2
resolver
uniprot_sec
Q9H2Z3
resolver
amino_acid_sequence
MSTVEEDSDTVTVETVNSVTLTQDTEGNLILHCPQNEADEIDSEDSIEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEVTEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGSGVPNSNTNSSVQHVQIRVARLEDNTAISSSPMAALQIPVQITHVSSADSPATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIQSSDFPEPPDALEADTFPDEIHHPKMTVEPSFNDAHVSKFSDQNSTELMNSVMVRTEEEISDTDLKQEESPSDLASAYVTEGLESPTIEEQVDQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH
uniprot
proteins
function
FUNCTION: Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5'-CCCG[GT]ATGT-3' (By similarity). Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1. {ECO:0000250, ECO:0000269|PubMed:12917399}.
uniprot
proteins
mass_dalton
84471
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by the cyclin-D2/CDK4, cyclin-D3/CDK4 and cyclin-D2/CDK6 complexes and to a lesser extent by the cyclin-D1/CDK4 complex. {ECO:0000250}.
uniprot
proteins
protein_family
DMTF1 family
uniprot
proteins
pubmed
10095122
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
12917399
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17936562
uniprot
proteins
sequence_length
760
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:17936562}.
uniprot
proteins