Sncg
entrez
20618
canonical
uniprot
Q9Z0F7
canonical
ensembl
ENSMUSG00000023064
resolver
ensp
ENSMUSP00000023826
resolver
enst
ENSMUST00000023826
resolver
genesymbol
Sncg
resolver
genesymbol_syn
Persyn
resolver
uniprot
Q5GQ64
resolver
uniprot_entry
Q5GQ64_MOUSE
resolver
uniprot_entry
SYUG_MOUSE
resolver
amino_acid_sequence
MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVANKTVEEAENIVVTTGVVRKEDLEPPAQDQEAKEQEENEEAKSGED
uniprot
proteins
function
FUNCTION: Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
13160
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Synuclein family
uniprot
proteins
pubmed
10051410
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16392033
uniprot
proteins
pubmed
20798282
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9801372
uniprot
proteins
pubmed
9925745
uniprot
proteins
sequence_length
123
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle (By similarity). {ECO:0000250}.
uniprot
proteins