ANGPTL7
entrez
10218
canonical
uniprot
O43827
canonical
ensembl
ENSG00000171819
resolver
ensp
ENSP00000366015
resolver
enst
ENST00000376819
resolver
genesymbol
ANGPTL7
resolver
genesymbol_syn
CDT6
resolver
hgnc
HGNC:24078
resolver
uniprot
B2R9B2
resolver
uniprot
F1T0A6
resolver
uniprot
Q4ZGK4
resolver
uniprot_entry
ANGL7_HUMAN
resolver
uniprot_sec
B2R9B2
resolver
uniprot_sec
F1T0A6
resolver
uniprot_sec
Q4ZGK4
resolver
amino_acid_sequence
MLKKPLSAVTWLCIFIVAFVSHPAWLQKLSKHKTPAQPQLKAANCCEEVKELKAQVANLSSLLSELNKKQERDWVSVVMQVMELESNSKRMESRLTDAESKYSEMNNQIDIMQLQAAQTVTQTSADAIYDCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWLGNEHIHRLSRQPTRLRVEMEDWEGNLRYAEYSHFVLGNELNSYRLFLGNYTGNVGNDALQYHNNTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHNKHLDGITWYGWHGSTYSLKRVEMKIRPEDFKP
uniprot
proteins
function
FUNCTION: Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193). Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036). {ECO:0000269|PubMed:21199193, ECO:0000269|PubMed:25622036}.
uniprot
proteins
mass_dalton
40018
uniprot
proteins
pubmed
11426320
uniprot
proteins
pubmed
11682471
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541013
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21199193
uniprot
proteins
pubmed
21697133
uniprot
proteins
pubmed
25622036
uniprot
proteins
pubmed
9727400
uniprot
proteins
sequence_length
346
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11682471}.
uniprot
proteins