Klhl10
entrez
66720
canonical
uniprot
Q9D5V2
canonical
ensembl
ENSMUSG00000001558
resolver
ensp
ENSMUSP00000001599
resolver
enst
ENSMUST00000001599
resolver
genesymbol
Klhl10
resolver
uniprot
A2A4I4
resolver
uniprot
B2RTD7
resolver
uniprot
Q8BVM3
resolver
uniprot
Q9DA07
resolver
uniprot_entry
B2RTD7_MOUSE
resolver
uniprot_entry
KLH10_MOUSE
resolver
uniprot_sec
A2A4I4
resolver
uniprot_sec
Q8BVM3
resolver
uniprot_sec
Q9DA07
resolver
amino_acid_sequence
MEMESTAASTRFHQPHMERKMSAMTCEIFNELRLEGKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISVLLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVGEYAARRDNFTGLALRDEVKYSASTSTLPV
uniprot
proteins
function
FUNCTION: May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. Required for male fertility. {ECO:0000269|PubMed:15136734, ECO:0000269|PubMed:16162871}.
uniprot
proteins
mass_dalton
68977
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
15136734
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16162871
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
608
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15136734}.
uniprot
proteins