Rpusd3
entrez
101122
canonical
uniprot
Q14AI6
canonical
ensembl
ENSMUSG00000051169
resolver
ensp
ENSMUSP00000059057
resolver
ensp
ENSMUSP00000108715
resolver
enst
ENSMUST00000060634
resolver
genesymbol
Rpusd3
resolver
uniprot
B7ZMQ0
resolver
uniprot
F7BS44
resolver
uniprot
Q3UZF6
resolver
uniprot
Q8BVS3
resolver
uniprot
Q8CHZ5
resolver
uniprot_entry
B7ZMQ0_MOUSE
resolver
uniprot_entry
F7BS44_MOUSE
resolver
uniprot_entry
RUSD3_MOUSE
resolver
uniprot_sec
Q3UZF6
resolver
uniprot_sec
Q8BVS3
resolver
uniprot_sec
Q8CHZ5
resolver
amino_acid_sequence
MGALRVLRYVSMIWRPELGSCARQRDAGFGTEARRPSQPHRSSKHKDLVEDQPFPGLLRTENLGLEELAHVLRAAVVDQKGPLVTLNKPQGLPVTGRPGELTLLSVLPQLSQALGLEHQELQVVRAPGKEASGLVLLSSCPQTASRLQKFFIHSRRAQRPTATYCAVTDGIPEPSEGTVCMPLKMEQMNDVDLAVPVMSPSRKDIQEGVKRTLSRFHVMATGRGCALVQLQPLTVFPNQLQVHMALQLCPILGDHTYAARVGTVLGQRFLWPAETTKPQRQVLDEALLRHLRLSPSQVAQMPLHLHLHRLLLPGTGSRDPPSELLAPLPPYFSRTLQCLRLSQQ
uniprot
proteins
ec_number
5.4.99.-
uniprot
proteins
function
FUNCTION: Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs), a post-transcriptional modification necessary for their translation. Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis. {ECO:0000250|UniProtKB:Q6P087}.
uniprot
proteins
mass_dalton
38076
uniprot
proteins
protein_family
Pseudouridine synthase RluA family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
344
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q6P087}. Note=Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly. {ECO:0000250|UniProtKB:Q6P087}.
uniprot
proteins