Fyb1
entrez
499537
canonical
uniprot
D3ZIE4
canonical
ensembl
ENSRNOG00000013886
resolver
ensembl
ENSRNOG00055006418
resolver
ensembl
ENSRNOG00060024494
resolver
ensembl
ENSRNOG00065022066
resolver
ensp
ENSRNOP00000018634
resolver
ensp
ENSRNOP00000083646
resolver
ensp
ENSRNOP00000101858
resolver
ensp
ENSRNOP00000104499
resolver
ensp
ENSRNOP00055008117
resolver
ensp
ENSRNOP00060035225
resolver
ensp
ENSRNOP00065030401
resolver
enst
ENSRNOT00000104137
resolver
enst
ENSRNOT00000134641
resolver
enst
ENSRNOT00000165112
resolver
enst
ENSRNOT00055010443
resolver
enst
ENSRNOT00060042527
resolver
enst
ENSRNOT00065037612
resolver
genesymbol
Fyb1
resolver
genesymbol_syn
Fyb
resolver
uniprot
A0A8I6G9A9
resolver
uniprot
A0ABK0LI43
resolver
uniprot_entry
A0A8I6G9A9_RAT
resolver
uniprot_entry
A0ABK0LI43_RAT
resolver
uniprot_entry
FYB1_RAT
resolver
amino_acid_sequence
MDGKTDVKSLMAKFNTGSNPTEEVSTSSRPFKVAGQNSPSGIQSKKNLFDNQGNASPPAGPSNMSKFGTTKPPLAAKPTYEEKSEKEPKPPFLKPTGVSPRFGTQPNSVSRDPEVKVGFLKPVSPKPTSLTKEDSKPVILRPPGNKLHNLNQESDLKTLGPKPGSTPPVPENDLKPGFSKIAGAKSKFMPAPQDADSKPRFPRHTYGQKPSLSTEDAQEEESIPKNTPVQKGSPVQLGAKSRGSPFKPAKEDPEDKDHGTPSSPFAGVVLKPAASRGSPGLSKNSEEKKEERKTDIPKNIFLNKLNQEEPARFPKAPSKLTAGTPWGQSQEKEGDKDSATPKQKPLPPLSVLGPPPSKPSRPPNVDLTRFRKADSANSSNKSQTPYSTTSLPPPPPTQPASQPPLPASHPAHLPAPSLPPRNIKPPLDLKHPINEENQDGVMHSDGTGNLEEEQESDGEMYEDIESSKERDKKREKEEKKRLELERKEQKEREKKEQELRKKFKLTGPIQVIHHAKACCDVKGGKNELSFKQGEDIEIIRITDNPEGKWLGRTARGSYGYIKTTAVKIDYDSLKRKKNTINAVPPRPVEEDQDVYDDVAEQDAPNSHSQSGSGGMFPPPPADDDIYDGIEEEDADDGSVPQVDEKTNAWSWGILKMLKGKDERKKSIREKPKVSESDSNEGSSFPSPHKQLDVGEEVYDDVDASDFPPPPAEMSQGMSVGKTKAEEKDPKKLKKQEKEEKDLRKKFKYDGEIRVLYSTKVASSLTSKKWGTRDLQIKPGESLEVIQSTDDTKVLCRNEEGKYGYVLRSYLVDNDGEIYDDIADGCIYDND
uniprot
proteins
function
FUNCTION: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells (By similarity). May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton (By similarity). Modulates the expression of IL2 (By similarity). Involved in platelet activation (By similarity). Prevents the degradation of SKAP1 and SKAP2 (By similarity). May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (PubMed:12681493). {ECO:0000250|UniProtKB:O15117, ECO:0000250|UniProtKB:O35601, ECO:0000269|PubMed:12681493}.
uniprot
proteins
mass_dalton
91412
uniprot
proteins
post_translational_modification
PTM: T-cell receptor ligation leads to increased tyrosine phosphorylation.
uniprot
proteins
pubmed
12681493
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
830
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O15117}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}. Cell junction {ECO:0000250|UniProtKB:O35601}. Note=Colocalizes with TMEM47 at cell-cell contacts in podocytes. {ECO:0000250|UniProtKB:O35601}.
uniprot
proteins