Fstl1
entrez
14314
canonical
uniprot
Q62356
canonical
ensembl
ENSMUSG00000022816
resolver
ensp
ENSMUSP00000110411
resolver
enst
ENSMUST00000114763
resolver
genesymbol
Fstl1
resolver
genesymbol_syn
Frp
resolver
genesymbol_syn
Fstl
resolver
genesymbol_syn
Tsc36
resolver
uniprot
Q6GTX2
resolver
uniprot
Q99JI9
resolver
uniprot_entry
FSTL1_MOUSE
resolver
uniprot_sec
Q6GTX2
resolver
uniprot_sec
Q99JI9
resolver
amino_acid_sequence
MWKRWLALSLVTIALVHGEEEPRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSASPSASPVVCYQANRDELRRRLIQWLEAEIIPDGWFSKGSNYSEILDKYFKSFDNGDSHLDSSEFLKFVEQNETAINITTYADQENNKLLRSLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCSCGHWVCTAMTCDGKNQKGVQTHTEEEKTGYVQELQKHQGTAEKTKKVNTKEI
uniprot
proteins
function
FUNCTION: Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (By similarity). Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (PubMed:19595790, PubMed:21826198). Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes (PubMed:20054002). Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (By similarity). {ECO:0000250|UniProtKB:Q12841, ECO:0000269|PubMed:19595790, ECO:0000269|PubMed:20054002, ECO:0000269|PubMed:21826198}.
uniprot
proteins
mass_dalton
34554
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16944957
uniprot
proteins
pubmed
19595790
uniprot
proteins
pubmed
20054002
uniprot
proteins
pubmed
21826198
uniprot
proteins
pubmed
31351024
uniprot
proteins
pubmed
7901004
uniprot
proteins
sequence_length
306
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins