Arsg
entrez
303631
canonical
uniprot
Q32KJ9
canonical
ensembl
ENSRNOG00000003931
resolver
ensembl
ENSRNOG00055030223
resolver
ensembl
ENSRNOG00060014875
resolver
ensembl
ENSRNOG00065020046
resolver
ensp
ENSRNOP00000086727
resolver
ensp
ENSRNOP00055043390
resolver
ensp
ENSRNOP00060020280
resolver
ensp
ENSRNOP00065027068
resolver
enst
ENSRNOT00000113597
resolver
enst
ENSRNOT00055052488
resolver
enst
ENSRNOT00060025440
resolver
enst
ENSRNOT00065033836
resolver
genesymbol
Arsg
resolver
uniprot_entry
ARSG_RAT
resolver
amino_acid_sequence
MGWLFLKVLLVGMVFSGLLYPFVDFSISGETRAPRPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPSFRGFDYYFGIPYSNDMGCTDNPGYNYPPCPACPQSDGRWRNPDRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLANPQSQRLYRASLQEMDSLVGQIKDKVDHVAKENTLLWFAGDNGPWAQKCELAGSMGPFSGLWQTHQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSLLDIFPTVIALAGASLPPNRKFDGVDVSEVLFGKSQTGHRVLFHPNSGAAGEYGALQTVRLDRYKAFYITGGAKACDGGVGPEQHHVSPLIFNLEDDAAESSPLQKGSPEYQELLPKVTRVLADVLQDIADDNSSQADYTQDPSVTPCCNPYQITCRCQPGE
uniprot
proteins
ec_number
3.1.6.1
uniprot
proteins
ec_number
3.1.6.15
uniprot
proteins
function
FUNCTION: Displays arylsulfatase activity at acidic pH towards the artificial substrate p-nitrocatechol sulfate (By similarity). Catalyzes the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin (By similarity). {ECO:0000250|UniProtKB:Q96EG1}.
uniprot
proteins
mass_dalton
57269
uniprot
proteins
post_translational_modification
PTM: N-glycosylated with both high mannose and complex type sugars. {ECO:0000250|UniProtKB:Q3TYD4}.; PTM: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. {ECO:0000250|UniProtKB:P15289}.; PTM: 63-kDa precursor undergoes proteolytic processing in two steps, yielding two fragments in the first step (apparent molecular masses of 44 and 18 kDa) (By similarity). In the second step, the 44-kDa fragment is processed further to the 34- and 10-kDa chains. The 10-kDa chain is a cleavage product of the 44-kDa fragment but linked to the 18-kDa chain through a disulfide bridge (By similarity). {ECO:0000250|UniProtKB:Q3TYD4}.
uniprot
proteins
protein_family
Sulfatase family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
16174644
uniprot
proteins
sequence_length
526
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000250|UniProtKB:Q3TYD4}. Note=The 63-kDa precursor protein localizes to pre-lysosomal compartments and tightly associates with organelle membranes, most likely the endoplasmic reticulum. In contrast, proteolytically processed fragments of 34-, 18- and 10-kDa are found in lysosomal fractions and lose their membrane association. {ECO:0000250|UniProtKB:Q3TYD4}.
uniprot
proteins