Thsd7a
entrez
330267
canonical
uniprot
Q69ZU6
canonical
ensembl
ENSMUSG00000032625
resolver
ensp
ENSMUSP00000113681
resolver
enst
ENSMUST00000119581
resolver
genesymbol
Thsd7a
resolver
genesymbol_syn
Gm837
resolver
genesymbol_syn
Kiaa0960
resolver
uniprot
E9Q6P0
resolver
uniprot
E9QNR5
resolver
uniprot
Q3TP01
resolver
uniprot
Q3UWV1
resolver
uniprot_entry
E9QNR5_MOUSE
resolver
uniprot_entry
THS7A_MOUSE
resolver
uniprot_sec
E9Q6P0
resolver
uniprot_sec
Q3TP01
resolver
uniprot_sec
Q3UWV1
resolver
amino_acid_sequence
MGLRAGRLASPSRGVLQLLRLPLLLLLLLSSGARGAAAQGDTEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQAVRPSNQQNCFKVCDWHKELYDWRLGTWDRCQPVISKSLEKSRECVKGEEGIQVREIMCIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQKDCIVSEFSPWSECSRTCGSGLQHRTRHVVAPPQYGGSGCPNLTEFQVCQSNPCEEDESLYSLQVGPWSACSVPHTRQARQARRRGKNKEREKERGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVTCLNRTGKSADLSFCQQERLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTITQFPIGSEKECPALEEKEPCVSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGVQTREIYCIQTNDNMLSHGNTQKDKEASKPVDSKLCTGPVPNTTQLCHVPCPIECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKSVRLGDCEPDNGKSCGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSSWSSCSHTCSGKTTEGKQTRARSILAYAGEEGGIRCPNISALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCVVTPYSDWTPCPSSCREGDSGARKQSRQRVIIQLPANGGKECSDPLYEEKACEAPPTCHSYRWKTHKWRRCQLVPWSIQQDVPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMKVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVDMRDNCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTCALPCNPSGSRQRSADPIRQPADEGRACPDAVEKEPCSLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWPMNTSCTVECPVNCQLSDWSSWSQCSQTCGLTGKMIRKRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSAEDFSKVVDEEFCANTELIIDGNKQIVLEETCTQPCPGDCYLNDWSSWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWVASAWKGSSRTVWCQRSDGINVTGGCLVVSQPDTDRSCNPPCSQPHSYCSEMKTCRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSINPAGRGRTWFLQPFGPDGRLKTWVYGVAAGAFVLLVFIVSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM
uniprot
proteins
function
FUNCTION: [Thrombospondin type-1 domain-containing protein 7A]: Plays a role in actin cytoskeleton rearrangement. {ECO:0000269|PubMed:27214550}.; FUNCTION: [Thrombospondin type-1 domain-containing protein 7A, soluble form]: The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism. {ECO:0000250|UniProtKB:Q9UPZ6}.
uniprot
proteins
mass_dalton
183527
uniprot
proteins
post_translational_modification
PTM: Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form. {ECO:0000250|UniProtKB:Q9UPZ6}.; PTM: Extensively N-glycosylated. {ECO:0000250|UniProtKB:Q9UPZ6}.
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27214550
uniprot
proteins
sequence_length
1645
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Thrombospondin type-1 domain-containing protein 7A]: Cell membrane {ECO:0000269|PubMed:27214550}; Single-pass type I membrane protein {ECO:0000305|PubMed:27214550}. Cell projection {ECO:0000269|PubMed:27214550}. Note=Detected on podocyte foot processes. {ECO:0000269|PubMed:27214550}.; SUBCELLULAR LOCATION: [Thrombospondin type-1 domain-containing protein 7A, soluble form]: Secreted {ECO:0000250|UniProtKB:Q9UPZ6}. Note=Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form. {ECO:0000250|UniProtKB:Q9UPZ6}.
uniprot
proteins
transmembrane_region
TRANSMEM 1596..1616; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins