BKGD
entrez
28970
canonical
uniprot
Q9H0W9
canonical
ensembl
ENSG00000182919
resolver
ensp
ENSP00000331209
resolver
ensp
ENSP00000346403
resolver
ensp
ENSP00000433721
resolver
ensp
ENSP00000433723
resolver
ensp
ENSP00000435113
resolver
ensp
ENSP00000442094
resolver
ensp
ENSP00000477694
resolver
ensp
ENSP00000576930
resolver
ensp
ENSP00000576931
resolver
ensp
ENSP00000576933
resolver
ensp
ENSP00000576934
resolver
ensp
ENSP00000576937
resolver
ensp
ENSP00000576940
resolver
ensp
ENSP00000576944
resolver
ensp
ENSP00000576949
resolver
ensp
ENSP00000576950
resolver
ensp
ENSP00000576958
resolver
ensp
ENSP00000576962
resolver
ensp
ENSP00000576963
resolver
ensp
ENSP00000576964
resolver
ensp
ENSP00000576966
resolver
ensp
ENSP00000576967
resolver
ensp
ENSP00000576968
resolver
ensp
ENSP00000576969
resolver
ensp
ENSP00000576971
resolver
ensp
ENSP00000587323
resolver
ensp
ENSP00000621734
resolver
enst
ENST00000617482
resolver
enst
ENST00000906878
resolver
enst
ENST00000906885
resolver
enst
ENST00000906890
resolver
enst
ENST00000906899
resolver
enst
ENST00000906903
resolver
enst
ENST00000906909
resolver
enst
ENST00000906912
resolver
enst
ENST00000917264
resolver
enst
ENST00000951675
resolver
genesymbol
BKGD
resolver
genesymbol
C11orf54
resolver
genesymbol_syn
C11orf54
resolver
hgnc
HGNC:30204
resolver
uniprot
A0A024R3B0
resolver
uniprot
A0A087WT99
resolver
uniprot
A8K718
resolver
uniprot
A8K850
resolver
uniprot
Q6FI88
resolver
uniprot
Q6XYB0
resolver
uniprot
Q96EI3
resolver
uniprot
Q96IX1
resolver
uniprot
Q9Y6B4
resolver
uniprot_entry
A0A024R3B0_HUMAN
resolver
uniprot_entry
A0A087WT99_HUMAN
resolver
uniprot_entry
A8K718_HUMAN
resolver
uniprot_entry
BKGD_HUMAN
resolver
uniprot_sec
A8K850
resolver
uniprot_sec
Q6FI88
resolver
uniprot_sec
Q6XYB0
resolver
uniprot_sec
Q96EI3
resolver
uniprot_sec
Q96IX1
resolver
uniprot_sec
Q9Y6B4
resolver
amino_acid_sequence
MACAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD
uniprot
proteins
ec_number
4.1.1.34
uniprot
proteins
function
FUNCTION: Catalyzes the decarboxylation of 3-dehydro-L-gulonate to produce L-xylulose, used in the pentose pathway (PubMed:40737316). Exhibits ester hydrolase activity on p-nitrophenyl acetate, in vitro (PubMed:16522806). Regulates DNA damage and repair by regulating HIF1A degradation via chaperone-mediated autophagy (CMA) (PubMed:37277441). {ECO:0000269|PubMed:16522806, ECO:0000269|PubMed:37277441, ECO:0000269|PubMed:40737316}.; FUNCTION: [Isoform 3]: Probably non-functional when tested on p-nitrophenyl acetate, in vitro. {ECO:0000305|PubMed:16522806}.
uniprot
proteins
mass_dalton
35117
uniprot
proteins
mutagenesis
MUTAGEN 217; /note="H->N: Abolishes enzyme activity."; /evidence="ECO:0000269|PubMed:40737316"; MUTAGEN 263; /note="R->Q: Abolishes enzyme activity."; /evidence="ECO:0000269|PubMed:40737316
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15498874
uniprot
proteins
pubmed
16522806
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
37277441
uniprot
proteins
pubmed
40737316
uniprot
proteins
sequence_length
315
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16522806}. Cytoplasm {ECO:0000269|PubMed:37277441}. Note=Mainly located in the cytoplasm. {ECO:0000269|PubMed:37277441}.
uniprot
proteins