Simc1
entrez
319719
canonical
uniprot
E9Q6E9
canonical
ensembl
ENSMUSG00000043183
resolver
ensp
ENSMUSP00000113676
resolver
ensp
ENSMUSP00000303947
resolver
ensp
ENSMUSP00000303952
resolver
genesymbol
Simc1
resolver
genesymbol_syn
4732471D19Rik
resolver
genesymbol_syn
Pleiad
resolver
uniprot
Q3TM32
resolver
uniprot
Q505H0
resolver
uniprot
Q8C747
resolver
uniprot
Q8CE66
resolver
uniprot_entry
Q505H0_MOUSE
resolver
uniprot_entry
SIMC1_MOUSE
resolver
uniprot_sec
Q3TM32
resolver
uniprot_sec
Q8C747
resolver
uniprot_sec
Q8CE66
resolver
amino_acid_sequence
MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRENRARTKDRNGLCVIDLTRNEEENRPIATLDLTLEPVASSQKEPTSLQTCTSLSGKEVMEAHEDRGSQPAAQRIINNDPVDLDLLEENLFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSSFSSTSNQRASLPCPQQDVPCQSQGLLCPLQALSCPQTASPCPPRASSCPPQALSCPPQALSCPSQTLQCQLQALPQPPQEVPCSTQNVPCPQQNMPSTPQGLSWHPRHTLYPYQDTLGLPQDVPGRPQNMSYPQDVTQLQDMPWSLHDMPLSLQDVLQSLQDVPPLLGDVPPSPEVMQLPGYVTQTSRDVIQSPAGVTQSLGSMMQSPGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVMQSPGGVTQSLRSVTQSPGGVMQSPGGVMQSPRDVMQSPRDVMQSPRDVMQSPRGVTQSLGSMMQSPGGVMQSLRSVMQSSGGVTQSLRSVMQSPGGVMQSPGGVTQSPRGMIKSPGMMLSPGDVIQSLNSVPQSSRDRMQSAGHVPSASGDAIQSPGGMSPTSRDRMQSPGGVSLATEDSIQLPGGVPLSSDVIQSQGGVPLSSKDRMQSPGGVPPSSGDMIQSQGGVPQSLGDAIQSAGGVPQSSGDAIQSPGGVSLATGDSIQLPGGVPLSSGDVIQSQGGVPRSSRDRMQSPGGVPPSSGGVIQSPGGVSPASGDAIQSPGSVLPASGDAIQSAGGVLLASGDAIQSPRSVPQSPSGTLRSPGNMSESLGDTPNLSGDVSNSPQALLDLARDRPKSSPNDVQNRDTPMDISASSSSSCSANPQSRQSEFKLDKVPWLTITDSSARREKSLPQLANPGSAQIQGQIPQVGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH
uniprot
proteins
function
FUNCTION: Inhibits the protease activity of CAPN3. May play a role in SMC5-SMC6 complex recruitment for viral restriction. Forms a complex with SLF2 and this complex is required to recruit SMC5-SMC6 complex to PML nuclear bodies and sites of viral replication. {ECO:0000250|UniProtKB:Q8NDZ2}.
uniprot
proteins
mass_dalton
146618
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23707407
uniprot
proteins
sequence_length
1354
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, PML body {ECO:0000250|UniProtKB:Q8NDZ2}.
uniprot
proteins