AGTRAP
entrez
57085
canonical
uniprot
Q6RW13
canonical
ensembl
ENSG00000177674
resolver
ensp
ENSP00000319713
resolver
ensp
ENSP00000365814
resolver
ensp
ENSP00000365816
resolver
ensp
ENSP00000365824
resolver
ensp
ENSP00000383688
resolver
ensp
ENSP00000408505
resolver
ensp
ENSP00000526609
resolver
ensp
ENSP00000526610
resolver
genesymbol
AGTRAP
resolver
genesymbol_syn
ATRAP
resolver
hgnc
HGNC:13539
resolver
uniprot
A8MVQ5
resolver
uniprot
Q5SNV4
resolver
uniprot
Q5SNV5
resolver
uniprot
Q96AC0
resolver
uniprot
Q96PL4
resolver
uniprot
Q9NRW9
resolver
uniprot_entry
ATRAP_HUMAN
resolver
uniprot_sec
A8MVQ5
resolver
uniprot_sec
Q5SNV4
resolver
uniprot_sec
Q5SNV5
resolver
uniprot_sec
Q96AC0
resolver
uniprot_sec
Q96PL4
resolver
uniprot_sec
Q9NRW9
resolver
amino_acid_sequence
MELPAVNLKVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY
uniprot
proteins
function
FUNCTION: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Also induces a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. {ECO:0000269|PubMed:12960423}.
uniprot
proteins
mass_dalton
17419
uniprot
proteins
pubmed
11733189
uniprot
proteins
pubmed
12960423
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
159
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Golgi apparatus membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:12960423}; Multi-pass membrane protein {ECO:0000269|PubMed:12960423}. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
uniprot
proteins
transmembrane_region
TRANSMEM 24..44; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 87..107; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins