DRC5
entrez
202500
canonical
uniprot
Q5JU00
canonical
ensembl
ENSG00000146221
resolver
ensp
ENSP00000360560
resolver
ensp
ENSP00000567195
resolver
enst
ENST00000371505
resolver
enst
ENST00000897136
resolver
genesymbol
DRC5
resolver
genesymbol_syn
TCTE1
resolver
hgnc
HGNC:11693
resolver
uniprot
B4DX59
resolver
uniprot
Q8IYS6
resolver
uniprot_entry
DRC5_HUMAN
resolver
uniprot_sec
B4DX59
resolver
uniprot_sec
Q8IYS6
resolver
amino_acid_sequence
MQDTVTTSALLDPSHSSVSTQDNSSTGGHTSSTSPQLSKPSITPVPAKSRNPHPRANIRRMRRIIAEDPEWSLAIVPLLTELCIQHIIRNFQKNPILKQMLPEHQQKVLNHLSPDLPLAVTANLIDSENYWLRCCMHRWPVCHVAHHGGSWKRMFFERHLENLLKHFIPGTTDPAVILDLLPLCRNYVRRVHVDQFLPPVQLPAQLRPGDQSDSGSEGEMEEPTVDHYQLGDLVAGLSHLEELDLVYDVKDCGMNFEWNLFLFTYRDCLSLAAAIKACHTLKIFKLTRSKVDDDKARIIIRSLLDHPVLEELDLSQNLIGDRGARGAAKLLSHSRLRVLNLANNQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLTTLHLGGNELSEPTATLLSQVLAINTTLTSINLSCNHIGLDGGKQLLEGMSDNKTLLEFDLRLSDVAQESEYLIGQALYANREAARQRALNPSHFMSTITANGPENSVG
uniprot
proteins
function
FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC. May be required for sperm motility. {ECO:0000250|UniProtKB:A6H639, ECO:0000250|UniProtKB:A8HMZ4}.
uniprot
proteins
mass_dalton
55632
uniprot
proteins
protein_family
DRC5 family
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
34169321
uniprot
proteins
sequence_length
501
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A6H639}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A8HMZ4}. Note=Detected along the length of the sperm flagellum. {ECO:0000250|UniProtKB:A6H639}.
uniprot
proteins