Lhcgr
entrez
25477
canonical
uniprot
P16235
canonical
ensembl
ENSRNOG00000016712
resolver
ensembl
ENSRNOG00055019047
resolver
ensembl
ENSRNOG00060003764
resolver
ensembl
ENSRNOG00065007702
resolver
ensp
ENSRNOP00000022481
resolver
genesymbol
Lhcgr
resolver
uniprot
P70646
resolver
uniprot
Q63807
resolver
uniprot
Q63808
resolver
uniprot
Q63809
resolver
uniprot
Q6LDI7
resolver
uniprot_entry
LSHR_RAT
resolver
uniprot_sec
P70646
resolver
uniprot_sec
Q63807
resolver
uniprot_sec
Q63808
resolver
uniprot_sec
Q63809
resolver
uniprot_sec
Q6LDI7
resolver
amino_acid_sequence
MGRRVPALRQLLVLAVLLLKPSQLQSRELSGSRCPEPCDCAPDGALRCPGPRAGLARLSLTYLPVKVIPSQAFRGLNEVVKIEISQSDSLERIEANAFDNLLNLSELLIQNTKNLLYIEPGAFTNLPRLKYLSICNTGIRTLPDVTKISSSEFNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLISLELKENIYLEKMHSGAFQGATGPSILDISSTKLQALPSHGLESIQTLIALSSYSLKTLPSKEKFTSLLVATLTYPSHCCAFRNLPKKEQNFSFSIFENFSKQCESTVRKADNETLYSAIFEENELSGWDYDYGFCSPKTLQCAPEPDAFNPCEDIMGYAFLRVLIWLINILAIFGNLTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCGAAGFFTVFASELSVYTLTVITLERWHTITYAVQLDQKLRLRHAIPIMLGGWLFSTLIATMPLVGISNYMKVSICLPMDVESTLSQVYILSILILNVVAFVVICACYIRIYFAVQNPELTAPNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFLLLLSRFGCCKRRAELYRRKEFSAYTSNCKNGFPGASKPSQATLKLSTVHCQQPIPPRALTH
uniprot
proteins
function
FUNCTION: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. {ECO:0000250|UniProtKB:P22888}.
uniprot
proteins
mass_dalton
78036
uniprot
proteins
mutagenesis
MUTAGEN 409; /note="D->N: Significant reduction of binding."; /evidence="ECO:0000269|PubMed:1714448"; MUTAGEN 436; /note="D->N: No change in binding or cAMP production."; /evidence="ECO:0000269|PubMed:1714448"; MUTAGEN 455; /note="E->Q: No change in binding or cAMP production."; /evidence="ECO:0000269|PubMed:1714448"; MUTAGEN 582; /note="D->N: No change in binding or cAMP production."; /evidence="ECO:0000269|PubMed:1714448"; MUTAGEN 647; /note="C->A: Trapped intracellularly and does not appear to become mature; when associated with A-648."; /evidence="ECO:0000269|PubMed:7776964"; MUTAGEN 648; /note="C->A: Trapped intracellularly and does not appear to become mature; when associated with A-647."; /evidence="ECO:0000269|PubMed:7776964
uniprot
proteins
post_translational_modification
PTM: Sulfated. {ECO:0000250|UniProtKB:P22888}.
uniprot
proteins
protein_family
FSH/LSH/TSH subfamily
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
1353463
uniprot
proteins
pubmed
1714448
uniprot
proteins
pubmed
1976554
uniprot
proteins
pubmed
2019252
uniprot
proteins
pubmed
2040640
uniprot
proteins
pubmed
2174034
uniprot
proteins
pubmed
2281186
uniprot
proteins
pubmed
2502842
uniprot
proteins
pubmed
2601325
uniprot
proteins
pubmed
2925659
uniprot
proteins
pubmed
7776964
uniprot
proteins
sequence_length
700
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P22888}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P22888}. Secreted. Note=Some isoforms may be secreted.
uniprot
proteins
transmembrane_region
TRANSMEM 363..390; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 400..422; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 444..466; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 487..509; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 530..551; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 575..598; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 610..631; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins