Gab1
entrez
14388
canonical
uniprot
Q9QYY0
canonical
ensembl
ENSMUSG00000031714
resolver
ensp
ENSMUSP00000034150
resolver
ensp
ENSMUSP00000147784
resolver
ensp
ENSMUSP00000159976
resolver
ensp
ENSMUSP00000159977
resolver
enst
ENSMUST00000034150
resolver
enst
ENSMUST00000210676
resolver
enst
ENSMUST00000249880
resolver
genesymbol
Gab1
resolver
uniprot
A0A1B0GS41
resolver
uniprot
A0AAQ4VMS8
resolver
uniprot
Q505A4
resolver
uniprot
Q91VW7
resolver
uniprot_entry
A0A1B0GS41_MOUSE
resolver
uniprot_entry
A0AAQ4VMS8_MOUSE
resolver
uniprot_entry
GAB1_MOUSE
resolver
uniprot_entry
Q505A4_MOUSE
resolver
uniprot_sec
Q91VW7
resolver
amino_acid_sequence
MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEDMNKWVRCICDICGFNPTEEDPVKPLTGSSQAPVDSPFAISTAPASSQMEASSVALPPPYQVISLPPHPDTLGLQDDPQDYLLLINCQSKKPEPNRTLFDSAKPTFSETDCNDNVPSHQTPASSQSKHGMNGFFQQQMMYDCPPSRLTSVSGESSLYNLPRSYSHDVLPKESPSSTEADGELYTFNTPSGTAGVETQMRHVSISYDIPPTPGNTYQIPRTFPESTLGQSSKLDTIPDIPPPRPPKPHPTHDRSPVETCGVPRTASDTDSSYCIPPPAGMTPSRSNTISTVDLNKLRKDASSQDCYDIPRTFPSDRSSSLEGFHSQYKIKSVLTAGGVSGEELDENYVPMNPNSPPRQHSGSFTEPIQEPNYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKVKPAPLDIKPLSEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNPNLSGEDPNLFASNSLDGGSSPMNKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSMADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPTKNVK
uniprot
proteins
function
FUNCTION: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway. {ECO:0000250|UniProtKB:Q13480}.
uniprot
proteins
mass_dalton
76812
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains. Phosphorylated on tyrosine residues by HCK upon IL6 signaling (By similarity). Phosphorylated in response to FGFR1 activation. {ECO:0000250, ECO:0000269|PubMed:11353842}.
uniprot
proteins
protein_family
GAB family
uniprot
proteins
pubmed
11353842
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20094046
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29408807
uniprot
proteins
sequence_length
695
uniprot
proteins