NMRK1
entrez
54981
canonical
uniprot
Q9NWW6
canonical
ensembl
ENSG00000106733
resolver
ensp
ENSP00000354387
resolver
ensp
ENSP00000366004
resolver
ensp
ENSP00000366007
resolver
ensp
ENSP00000578119
resolver
ensp
ENSP00000627247
resolver
ensp
ENSP00000627249
resolver
enst
ENST00000376811
resolver
genesymbol
NMRK1
resolver
genesymbol_syn
C9orf95
resolver
genesymbol_syn
NRK1
resolver
hgnc
HGNC:26057
resolver
uniprot
B3KUG3
resolver
uniprot
Q5W124
resolver
uniprot
Q5W125
resolver
uniprot
Q8N430
resolver
uniprot_entry
B3KUG3_HUMAN
resolver
uniprot_entry
NRK1_HUMAN
resolver
uniprot_entry
Q5W125_HUMAN
resolver
uniprot_sec
Q5W124
resolver
uniprot_sec
Q8N430
resolver
amino_acid_sequence
MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEALNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSYFLTIPYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQVYEDLIQELAKQKCLQVTA
uniprot
proteins
ec_number
2.7.1.173
uniprot
proteins
ec_number
2.7.1.22
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3-deazaguanosine. {ECO:0000269|PubMed:15137942}.
uniprot
proteins
mass_dalton
23193
uniprot
proteins
mutagenesis
MUTAGEN 16; /note="K->A: Loss of activity."; /evidence="ECO:0000269|PubMed:17698003"; MUTAGEN 36; /note="D->A: Loss of activity."; /evidence="ECO:0000269|PubMed:17698003, ECO:0000269|PubMed:17914902"; MUTAGEN 56; /note="D->A: Loss of activity."; /evidence="ECO:0000269|PubMed:17698003"; MUTAGEN 98; /note="E->A: Loss of activity."; /evidence="ECO:0000269|PubMed:17914902"; MUTAGEN 138; /note="D->A: Almost no effect."; /evidence="ECO:0000269|PubMed:17698003
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis. {ECO:0000305|PubMed:17914902}.
uniprot
proteins
protein_family
NRK subfamily
uniprot
proteins
protein_family
Uridine kinase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15137942
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17698003
uniprot
proteins
pubmed
17914902
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8809081
uniprot
proteins
sequence_length
199
uniprot
proteins