Ptgir
entrez
292661
canonical
uniprot
P43253
canonical
ensembl
ENSRNOG00000016756
resolver
ensp
ENSRNOP00000022461
resolver
enst
ENSRNOT00000022461
resolver
genesymbol
Ptgir
resolver
uniprot_entry
PI2R_RAT
resolver
amino_acid_sequence
MVASGGRPDGPPSITPESPLIVGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSPQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLCHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTGIMAVCSLPLTIRGFTQAIAPDSREMGDLHAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQTPLSRPVSGRRDTLAPDSLQAKEGNWVPLSTWGTGQVAPLTAVPLSGGDGCSVGMPSKTEAVVACSLC
uniprot
proteins
function
FUNCTION: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
uniprot
proteins
mass_dalton
44662
uniprot
proteins
post_translational_modification
PTM: Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. {ECO:0000250}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
7803522
uniprot
proteins
sequence_length
416
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 46..67; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 81..105; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 124..144; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 164..187; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 216..237; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 265..289; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 303..323; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins