Olah
entrez
64669
canonical
uniprot
P08635
canonical
ensembl
ENSRNOG00000016403
resolver
ensembl
ENSRNOG00055010942
resolver
ensembl
ENSRNOG00060008350
resolver
ensembl
ENSRNOG00065006720
resolver
ensp
ENSRNOP00000022043
resolver
ensp
ENSRNOP00055014922
resolver
ensp
ENSRNOP00060010605
resolver
ensp
ENSRNOP00065007669
resolver
enst
ENSRNOT00000022043
resolver
enst
ENSRNOT00055018540
resolver
enst
ENSRNOT00060013894
resolver
enst
ENSRNOT00065010444
resolver
genesymbol
Olah
resolver
genesymbol_syn
Mch
resolver
genesymbol_syn
Thedc1
resolver
uniprot_entry
SAST_RAT
resolver
amino_acid_sequence
METAVNAKSPRNEKVLNCLYQNPDAVFKLICFPWAGGGSIHFAKWGQKINDSLEVHAVRLAGRETRLGEPFANDIYQIADEIVTALLPIIQDKAFAFFGHSFGSYIALITALLLKEKYKMEPLHIFVSGASAPHSTSRPQVPDLNELTEEQVRHHLLDFGGTPKHLIEDQDVLRMFIPLLKADAGVVKKFIFDKPSKALLSLDITGFLGSEDTIKDIEGWQDLTSGKFDVHMLPGDHFYLMKPDNENFIKNYIAKCLELSSLT
uniprot
proteins
ec_number
3.1.2.14
uniprot
proteins
function
FUNCTION: Contributes to the release of free fatty acids from fatty acid synthase (FASN). Has broad substrate specificity, giving rise to a range of free fatty acids with chain lengths between 10 and 16 carbon atoms (C10 - C16). {ECO:0000269|PubMed:8446599}.
uniprot
proteins
mass_dalton
29471
uniprot
proteins
mutagenesis
MUTAGEN 101; /note="S->A: Loss of thioesterase activity."; /evidence="ECO:0000269|PubMed:8446599"; MUTAGEN 101; /note="S->C: Decreased thioesterase activity."; /evidence="ECO:0000269|PubMed:8446599"; MUTAGEN 236; /note="D->A: Moderately decreased thioesterase activity."; /evidence="ECO:0000269|PubMed:8446599"; MUTAGEN 237; /note="H->A: Loss of thioesterase activity."; /evidence="ECO:0000269|PubMed:8446599"; MUTAGEN 262..263; /note="Missing: Strongly decreased thioesterase activity with FASN-bound fatty acids. No effect on thioesterase activity with free decanoyl coenzyme A."; /evidence="ECO:0000269|PubMed:8446599"; MUTAGEN 262; /note="L->A: Strongly decreased thioesterase activity with FASN-bound fatty acids. No effect on thioesterase activity with free decanoyl coenzyme A."; /evidence="ECO:0000269|PubMed:8446599"; MUTAGEN 263; /note="T->V: No effect on thioesterase activity."; /evidence="ECO:0000269|PubMed:8446599
uniprot
proteins
protein_family
Thioesterase family
uniprot
proteins
pubmed
3104035
uniprot
proteins
pubmed
3105579
uniprot
proteins
pubmed
3567174
uniprot
proteins
pubmed
3632637
uniprot
proteins
pubmed
8446599
uniprot
proteins
sequence_length
263
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:3105579}.
uniprot
proteins