SENP5
entrez
205564
canonical
uniprot
Q96HI0
canonical
ensembl
ENSG00000119231
resolver
ensp
ENSP00000327197
resolver
ensp
ENSP00000390231
resolver
ensp
ENSP00000685947
resolver
ensp
ENSP00000789185
resolver
genesymbol
SENP5
resolver
hgnc
HGNC:28407
resolver
uniprot
B2R9F5
resolver
uniprot
B4DY82
resolver
uniprot
Q96SA5
resolver
uniprot_entry
B2R9F5_HUMAN
resolver
uniprot_entry
SENP5_HUMAN
resolver
uniprot_sec
B4DY82
resolver
uniprot_sec
Q96SA5
resolver
amino_acid_sequence
MKKQRKILWRKGIHLAFSEKWNTGFGGFKKFYFHQHLCILKAKLGRPVTWNRQLRHFQGRKKALQIQKTWIKDEPLCAKTKFNVATQNVSTLSSKVKRKDAKHFISSSKTLLRLQAEKLLSSAKNSDHEYCREKNLLKAVTDFPSNSALGQANGHRPRTDPQPSDFPMKFNGESQSPGESGTIVVTLNNHKRKGFCYGCCQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMIRFRYRILRSQHFRTKSKVCKLRKAQRSWVQKVTGDHQETRRENGEGGSCSPFPSPEPKDPSCRHQPYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSSCSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADTSVSSVDGPVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNRKPFINREITNYRARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLMD
uniprot
proteins
ec_number
3.4.22.-
uniprot
proteins
function
FUNCTION: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. {ECO:0000269|PubMed:16608850, ECO:0000269|PubMed:16738315}.
uniprot
proteins
mass_dalton
86693
uniprot
proteins
mutagenesis
MUTAGEN 713; /note="C->A: Abolishes enzymatic activity."; /evidence="ECO:0000269|PubMed:16608850, ECO:0000269|PubMed:16738315
uniprot
proteins
protein_family
Peptidase C48 family
uniprot
proteins
pubmed
10806345
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16608850
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
16738315
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
25406032
uniprot
proteins
sequence_length
755
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16608850, ECO:0000269|PubMed:16738315}.
uniprot
proteins