Rad51d
entrez
19364
canonical
uniprot
O55230
canonical
ensembl
ENSMUSG00000018841
resolver
ensp
ENSMUSP00000018985
resolver
ensp
ENSMUSP00000021033
resolver
ensp
ENSMUSP00000090520
resolver
ensp
ENSMUSP00000277010
resolver
enst
ENSMUST00000018985
resolver
enst
ENSMUST00000092844
resolver
genesymbol
Rad51d
resolver
genesymbol_syn
R51h3
resolver
genesymbol_syn
Rad51l3
resolver
genesymbol_syn
Trad
resolver
uniprot
B1ARD4
resolver
uniprot
B5LBC4
resolver
uniprot
Q3UGT8
resolver
uniprot
Q9EP65
resolver
uniprot
Q9EP85
resolver
uniprot
Q9EP87
resolver
uniprot
Q9EP92
resolver
uniprot
Q9EPA9
resolver
uniprot
Q9EPC0
resolver
uniprot_entry
B1ARD4_MOUSE
resolver
uniprot_entry
B5LBC4_MOUSE
resolver
uniprot_entry
Q3UGT8_MOUSE
resolver
uniprot_entry
RA51D_MOUSE
resolver
uniprot_sec
Q9EP65
resolver
uniprot_sec
Q9EP85
resolver
uniprot_sec
Q9EP87
resolver
uniprot_sec
Q9EP92
resolver
uniprot_sec
Q9EPA9
resolver
uniprot_sec
Q9EPC0
resolver
amino_acid_sequence
MGMLRAGLCPGLTEETVQLLRGRKIKTVADLAAADLEEVAQKCGLSYKALVALRRVLLAQFSAFPLNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCVAANVAHSLQQNVLYVDSNGGMTASRLLQLLQARTQDEEKQASALQRIQVVRSFDIFRMLDMLQDLRGTIAQQEATSSGAVKVVIVDSVTAVVAPLLGGQQREGLALMMQLARELKILARDLGVAVVVTNHLTRDWDGRRFKPALGRSWSFVPSTRILLDVTEGAGTLGSSQRTVCLTKSPRQPTGLQEMIDIGTLGTEEQSPELPGKQT
uniprot
proteins
function
FUNCTION: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents (PubMed:19327148). Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM (By similarity). {ECO:0000250|UniProtKB:O75771, ECO:0000269|PubMed:15109494, ECO:0000269|PubMed:19327148}.; FUNCTION: [Isoform 2]: Contrary to isoform 1, does not show any repair activity, following treatment with mitomycin C. {ECO:0000269|PubMed:19327148}.; FUNCTION: [Isoform 3]: Contrary to isoform 1, does not show any repair activity, following treatment with mitomycin C. {ECO:0000269|PubMed:19327148}.; FUNCTION: [Isoform 4]: Contrary to isoform 1, does not show any repair activity, following treatment with mitomycin C. {ECO:0000269|PubMed:19327148}.; FUNCTION: [Isoform 5]: Contrary to isoform 1, does not show any repair activity, following treatment with mitomycin C. {ECO:0000269|PubMed:19327148}.; FUNCTION: [Isoform 6]: Contrary to isoform 1, does not show any repair activity, following treatment with mitomycin C. {ECO:0000269|PubMed:19327148}.; FUNCTION: [Isoform 7]: Contrary to isoform 1, does not show any repair activity, following treatment with mitomycin C. {ECO:0000269|PubMed:19327148}.
uniprot
proteins
mass_dalton
35260
uniprot
proteins
protein_family
RAD51 subfamily
uniprot
proteins
protein_family
RecA family
uniprot
proteins
pubmed
10705376
uniprot
proteins
pubmed
14704354
uniprot
proteins
pubmed
15109494
uniprot
proteins
pubmed
15297144
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19327148
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
9512535
uniprot
proteins
pubmed
9570954
uniprot
proteins
sequence_length
329
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19327148}. Chromosome, telomere {ECO:0000269|PubMed:15109494}. Cytoplasm {ECO:0000269|PubMed:19327148}.
uniprot
proteins