Q5XIB1
uniprot
Q5XIB1
canonical
amino_acid_sequence
MAETEAGLEVEEPTEDDTLPSDTVSLSDSDSDLSLPSGVEVQALSPERLSGESQEDSGPDDPPSHPTGIPTTAVQPFHLRGMSSTFSQRSHSIFDCLESAARQEPCSAPQTSVVDNCSFKRPVAPPSQTPARSLSRVHGNTDPTRVHPVPDYVSHPERWTKYSLEDVSETSEQSNRDAALAFLSSRSQASPTDYVPFFNQDPSSCGEGRVVFTKPVRGSEARAERKRVLKKGVVSGAGGEASVELAHLAGPEAEEWSGHQGQPEVVVPSEAARPESSSGPIGMKTVGFHGSKKRSRDHFRNRDSNPEGPGSERGPSV
uniprot
proteins
function
FUNCTION: Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus. Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing. Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP. {ECO:0000250|UniProtKB:Q9Y5U2}.
uniprot
proteins
mass_dalton
33939
uniprot
proteins
protein_family
TSSC4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y5U2}. Cytoplasm {ECO:0000250|UniProtKB:Q9Y5U2}. Note=Shuttles between the cytoplasm and the nucleus, associated with the U5 snRNP. {ECO:0000250|UniProtKB:Q9Y5U2}.
uniprot
proteins