PON2
entrez
5445
canonical
uniprot
Q15165
canonical
ensembl
ENSG00000105854
resolver
ensp
ENSP00000222572
resolver
ensp
ENSP00000404622
resolver
ensp
ENSP00000488378
resolver
ensp
ENSP00000527191
resolver
enst
ENST00000633192
resolver
genesymbol
PON2
resolver
hgnc
HGNC:9205
resolver
uniprot
A0A0J9YXF2
resolver
uniprot
A4D1H7
resolver
uniprot
B2RCP9
resolver
uniprot
B4DJD5
resolver
uniprot
O15114
resolver
uniprot
O15115
resolver
uniprot
O75856
resolver
uniprot
Q5FBX7
resolver
uniprot
Q86YL0
resolver
uniprot_entry
A0A0J9YXF2_HUMAN
resolver
uniprot_entry
PON2_HUMAN
resolver
uniprot_sec
A4D1H7
resolver
uniprot_sec
B2RCP9
resolver
uniprot_sec
B4DJD5
resolver
uniprot_sec
O15114
resolver
uniprot_sec
O15115
resolver
uniprot_sec
O75856
resolver
uniprot_sec
Q5FBX7
resolver
uniprot_sec
Q86YL0
resolver
amino_acid_sequence
MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
uniprot
proteins
ec_number
3.1.1.2
uniprot
proteins
ec_number
3.1.1.81
uniprot
proteins
function
FUNCTION: Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. {ECO:0000269|PubMed:11579088, ECO:0000269|PubMed:15772423}.
uniprot
proteins
mass_dalton
39381
uniprot
proteins
post_translational_modification
PTM: The signal sequence is not cleaved. {ECO:0000250}.
uniprot
proteins
protein_family
Paraoxonase family
uniprot
proteins
pubmed
11579088
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772423
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
8661009
uniprot
proteins
pubmed
9329371
uniprot
proteins
pubmed
9443862
uniprot
proteins
pubmed
9714608
uniprot
proteins
sequence_length
354
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:11579088}; Peripheral membrane protein {ECO:0000269|PubMed:11579088}.
uniprot
proteins