Tmem109
entrez
68539
canonical
uniprot
Q3UBX0
canonical
ensembl
ENSMUSG00000034659
resolver
ensp
ENSMUSP00000039529
resolver
ensp
ENSMUSP00000120261
resolver
enst
ENSMUST00000038128
resolver
genesymbol
Tmem109
resolver
uniprot
Q8R006
resolver
uniprot_entry
TM109_MOUSE
resolver
uniprot_sec
Q8R006
resolver
amino_acid_sequence
MAGAHSTPLWSRHLLKAVLMVLVALFLVHSASAQSHREFASPGQQKKETSADILTQIGRSLKEMLDTWLGPETMHVISETLLQVMWAISSAISVACFALSGIAAQLLSALGLDGEQLTQGLKLSPSQVQTLLLWGAAALVIYWLLSLLLGLVLALLGRILGGLKLVLFVAGFVALVRSVPDPSTRALMLLALLTLFALLSRLTGSRSSGSHLEAKVRGLERQIEELRGRQRRAAKMPRSMEEE
uniprot
proteins
function
FUNCTION: Functions as a voltage-gated monoatomic cation channel permeable to both potassium and calcium (By similarity). Plays a role in the cellular response to DNA damage (PubMed:20060811). {ECO:0000250|UniProtKB:O77751, ECO:0000269|PubMed:20060811}.
uniprot
proteins
mass_dalton
26306
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20060811
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
243
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus outer membrane {ECO:0000250|UniProtKB:O77751}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O77751}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O77751}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O77751}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:O77751}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O77751}.
uniprot
proteins
transmembrane_region
TRANSMEM 84..104; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 186..205; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins