Mboat7
entrez
77582
canonical
uniprot
Q8CHK3
canonical
ensembl
ENSMUSG00000035596
resolver
ensp
ENSMUSP00000037107
resolver
ensp
ENSMUSP00000188520
resolver
enst
ENSMUST00000038608
resolver
genesymbol
Mboat7
resolver
genesymbol_syn
Bb1
resolver
genesymbol_syn
Leng4
resolver
genesymbol_syn
Lpiat1
resolver
genesymbol_syn
Oact7
resolver
uniprot
Q3UDM6
resolver
uniprot
Q8R1P9
resolver
uniprot
Q9CY76
resolver
uniprot_entry
MBOA7_MOUSE
resolver
uniprot_sec
Q3UDM6
resolver
uniprot_sec
Q8R1P9
resolver
uniprot_sec
Q9CY76
resolver
amino_acid_sequence
MTPEEWTYLMVLLISIPVGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHSLHSLITILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEIASGFHKEPTLGLLPEVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPEAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPTRLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEIAASLEYDYETIRNIDCYGTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPFRSYVLRSAWTMLLSAYWHGLHPGYYLSFMTIPLCLAAEGYLESALRRHLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSMADTLRYWASIYFWVHFLALACLGLGLVLGGGSPSKRKTPSQATSSQAKEKLREE
uniprot
proteins
ec_number
2.3.1.-
uniprot
proteins
function
FUNCTION: Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (PubMed:23097495, PubMed:23472195, PubMed:32253259). Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell (PubMed:23097495, PubMed:23472195). In liver, participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation (PubMed:32253259). {ECO:0000269|PubMed:23097495, ECO:0000269|PubMed:23472195, ECO:0000269|PubMed:32253259}.
uniprot
proteins
mass_dalton
53436
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; phospholipid metabolism. {ECO:0000269|PubMed:23097495, ECO:0000269|PubMed:23472195}.
uniprot
proteins
protein_family
Membrane-bound acyltransferase family
uniprot
proteins
pubmed
15065000
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18094042
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23097495
uniprot
proteins
pubmed
23472195
uniprot
proteins
pubmed
32253259
uniprot
proteins
sequence_length
473
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q96N66}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q96N66}. Note=Localized in specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. {ECO:0000250|UniProtKB:Q96N66}.
uniprot
proteins
transmembrane_region
TRANSMEM 6..22; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q96N66"; TRANSMEM 34..57; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q96N66"; TRANSMEM 74..93; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q96N66"; TRANSMEM 195..212; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q96N66"; TRANSMEM 232..261; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q96N66"; TRANSMEM 427..447; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q96N66
uniprot
proteins