TBC1D31
entrez
93594
canonical
uniprot
Q96DN5
canonical
ensembl
ENSG00000156787
resolver
ensp
ENSP00000287380
resolver
ensp
ENSP00000312701
resolver
ensp
ENSP00000429334
resolver
ensp
ENSP00000535480
resolver
ensp
ENSP00000535482
resolver
ensp
ENSP00000535483
resolver
ensp
ENSP00000714635
resolver
ensp
ENSP00000752995
resolver
ensp
ENSP00000752996
resolver
enst
ENST00000522420
resolver
genesymbol
TBC1D31
resolver
genesymbol_syn
WDR67
resolver
hgnc
HGNC:30888
resolver
uniprot
B7ZL19
resolver
uniprot
E7ERK7
resolver
uniprot
Q2M2J9
resolver
uniprot
Q3MIR6
resolver
uniprot
Q8TBP9
resolver
uniprot_entry
E7ERK7_HUMAN
resolver
uniprot_entry
TBC31_HUMAN
resolver
uniprot_sec
B7ZL19
resolver
uniprot_sec
Q2M2J9
resolver
uniprot_sec
Q3MIR6
resolver
uniprot_sec
Q8TBP9
resolver
amino_acid_sequence
MQSTDLGNKESGKIWHRKPSPATRDGIIVNIIHNTSDYHPKVLRFLNVAFDGTGDCLIAGDHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVSWMRGHESSVFSISVHASGKYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLSNTILSCFKDNSIFAWECDTLFCKYQLPAPPESSSILYKVFAVTRDGRILAAGGKSNHLHLWCLEARQLFRIIQMPTKVRAIRHLEFLPDSFDAGSNQVLGVLSQDGIMRFINMQTCKLLFEIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALTQEINKPPPPLVKVIEDLPKNKLSSSDLKMKVTSGRVQQPAKSRESKMQTRILKQDLTGDFESKKNELPDGLNKKRLQILLKGYGEYPTKYRMFIWRSLLQLPENHTAFSTLIDKGTHVAFLNLQKKYPIKSRKLLRVLQRTLSALAHWSVIFSDTPYLPLLAFPFVKLFQNNQLICFEVIATLIINWCQHWFEYFPNPPINILSMIENVLAFHDKELLQHFIDHDITSQLYAWPLLETVFSEVLTREEWLKLFDNIFSNHPSFLLMTVVAYNICSRTPLLSCNLKDDFEFFFHHRNNLDINVVIRQVYHLMETTPTDIHPDSMLNVFVALTKGQYPVFNQYPKFIVDYQTQERERIRNDELDYLRERQTVEDMQAKVDQQRVEDEAWYQKQELLRKAEETRREMLLQEEEKMIQQRQRLAAVKRELKVKEMHLQDAARRRFLKLQQDQQEMELRRLDDEIGRKVYMRDREIAATARDLEMRQLELESQKRLYEKNLTENQEALAKEMRADADAYRRKVDLEEHMFHKLIEAGETQSQKTQKVIKENLAKAEQACLNTDWQIQSLHKQKCDDLQRNKCYQEVAKLLRENRRKEIEIINAMVEEEAKKWKEAEGKEFRLRSAKKASALSDASRKWFLKQEINAAVEHAENPCHKEEPRFQNEQDSSCLPRTSQLNDSSEMDPSTQISLNRRAVEWDTTGQNLIKKVRNLRQRLTARARHRCQTPHLLAA
uniprot
proteins
function
FUNCTION: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation. {ECO:0000269|PubMed:33934390}.
uniprot
proteins
mass_dalton
124189
uniprot
proteins
mutagenesis
MUTAGEN 1053..1056; /note="RARH->AADA: Loss of interaction with PJA2."; /evidence="ECO:0000269|PubMed:33934390
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26638075
uniprot
proteins
pubmed
33934390
uniprot
proteins
sequence_length
1066
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:33934390}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:26638075}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:33934390}.
uniprot
proteins