Gga2
entrez
74105
canonical
uniprot
Q6P5E6
canonical
ensembl
ENSMUSG00000030872
resolver
ensp
ENSMUSP00000033160
resolver
genesymbol
Gga2
resolver
genesymbol_syn
Kiaa1080
resolver
uniprot
Q3U374
resolver
uniprot
Q6PFX3
resolver
uniprot
Q6ZPY8
resolver
uniprot
Q8BM76
resolver
uniprot
Q9DC15
resolver
uniprot_entry
GGA2_MOUSE
resolver
uniprot_sec
Q3U374
resolver
uniprot_sec
Q6PFX3
resolver
uniprot_sec
Q6ZPY8
resolver
uniprot_sec
Q8BM76
resolver
uniprot_sec
Q9DC15
resolver
amino_acid_sequence
MAATAVAAGTGSPAGTESAEGGPGAAAALELWLNKATDPSMAEQDWSAIQKFCEQVNTDPSGPTHAPWLLAHKIQSPQEKEALYALTVLEICMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGAWATEKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQGIIKQDPKLPMDKILPPPSPWPKSIFDADEEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSRRVSAVEEVRSHVRVLREMLSMYRRPGHALPDQQALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVRLYKQVVEGRVSAGNAVPAAVGAIPAPRAFPNPEPCGLNCPLIDLETPSLLHQDLAALGINDVPTRNQVVIPSCCNDKKQPGAITLMGGGIQSLSADRNLLDLFSPQPSPGLNYVPQKSIPKEVPPGTKASPGWSWEAGPLASSTASQNTPLAHVFVPLESVKPSSLPPIVVYDRNGFRILLHFSQTGAPGHPDVKVLLLTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQTLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLSTA
uniprot
proteins
function
FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network. {ECO:0000250|UniProtKB:Q9UJY4}.
uniprot
proteins
mass_dalton
66049
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated. {ECO:0000250}.
uniprot
proteins
protein_family
GGA protein family
uniprot
proteins
pubmed
11950392
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19864490
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
603
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q9UJY4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UJY4}. Endosome membrane {ECO:0000250|UniProtKB:Q9UJY4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UJY4}. Early endosome membrane {ECO:0000250|UniProtKB:Q9UJY4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9UJY4}.
uniprot
proteins