Apool
entrez
68117
canonical
uniprot
Q78IK4
canonical
ensembl
ENSMUSG00000025525
resolver
ensp
ENSMUSP00000026599
resolver
ensp
ENSMUSP00000109042
resolver
enst
ENSMUST00000026599
resolver
enst
ENSMUST00000113415
resolver
genesymbol
Apool
resolver
genesymbol_syn
Fam121a
resolver
genesymbol_syn
Mic27
resolver
uniprot
B1AV14
resolver
uniprot_entry
B1AV14_MOUSE
resolver
uniprot_entry
MIC27_MOUSE
resolver
amino_acid_sequence
MAAFRMGKLTTIPAGLIYASINVRLAKEEEPKKQLVRPDQLPIYTAPPLHSKYVEEQPGNLQRGFASIRTTTVYYIGWCKSIYLFMKNGVMDTVQFGKDAYVYLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIAYPLGLATLGATVCYPAQSVIIAKITGKKAYATSQQIFQAIKSLWTQKSENESLPEPKEESKEGRSDEIHASLPDLKHSVSLPKELASATVIKSESTSGTTQFIPDPKLMDHGQSHPDDKDMYSTRS
uniprot
proteins
function
FUNCTION: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function. {ECO:0000250|UniProtKB:Q6UXV4}.
uniprot
proteins
mass_dalton
29261
uniprot
proteins
protein_family
Apolipoprotein O/MICOS complex subunit Mic27 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
265
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q6UXV4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q6UXV4}. Mitochondrion {ECO:0000250|UniProtKB:Q6UXV4}.
uniprot
proteins
transmembrane_region
TRANSMEM 111..129; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 138..155; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins