Ptp4a2
entrez
19244
canonical
uniprot
O70274
canonical
ensembl
ENSMUSG00000028788
resolver
ensp
ENSMUSP00000030578
resolver
ensp
ENSMUSP00000125901
resolver
ensp
ENSMUSP00000316377
resolver
ensp
ENSMUSP00000316378
resolver
ensp
ENSMUSP00000341825
resolver
enst
ENSMUST00000030578
resolver
enst
ENSMUST00000165853
resolver
genesymbol
Ptp4a2
resolver
genesymbol_syn
Prl2
resolver
uniprot
Q3U1K7
resolver
uniprot_entry
TP4A2_MOUSE
resolver
uniprot_sec
Q3U1K7
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by sodium orthovanadate and pentamidine. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
19127
uniprot
proteins
mutagenesis
MUTAGEN 164..167; /note="Missing: Locates in the nucleus."; /evidence="ECO:0000269|PubMed:10747914
uniprot
proteins
post_translational_modification
PTM: Farnesylated. Farnesylation is required for membrane targeting and for interaction with RABGGTB (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
10747914
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9514946
uniprot
proteins
sequence_length
167
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10747914}. Early endosome {ECO:0000269|PubMed:10747914}. Cytoplasm {ECO:0000269|PubMed:10747914}.
uniprot
proteins