KCNS3
entrez
3790
canonical
uniprot
Q9BQ31
canonical
ensembl
ENSG00000170745
resolver
ensp
ENSP00000305824
resolver
ensp
ENSP00000385968
resolver
ensp
ENSP00000539630
resolver
ensp
ENSP00000539631
resolver
ensp
ENSP00000539632
resolver
ensp
ENSP00000539633
resolver
ensp
ENSP00000539634
resolver
ensp
ENSP00000539635
resolver
ensp
ENSP00000539636
resolver
ensp
ENSP00000590690
resolver
ensp
ENSP00000590691
resolver
ensp
ENSP00000590692
resolver
ensp
ENSP00000590693
resolver
ensp
ENSP00000590694
resolver
ensp
ENSP00000624252
resolver
ensp
ENSP00000624253
resolver
ensp
ENSP00000624254
resolver
ensp
ENSP00000624255
resolver
ensp
ENSP00000624256
resolver
enst
ENST00000304101
resolver
enst
ENST00000403915
resolver
enst
ENST00000869571
resolver
enst
ENST00000869572
resolver
enst
ENST00000869573
resolver
enst
ENST00000869574
resolver
enst
ENST00000869575
resolver
enst
ENST00000869576
resolver
enst
ENST00000869577
resolver
enst
ENST00000920631
resolver
enst
ENST00000920632
resolver
enst
ENST00000920633
resolver
enst
ENST00000920634
resolver
enst
ENST00000920635
resolver
enst
ENST00000954193
resolver
enst
ENST00000954194
resolver
enst
ENST00000954195
resolver
enst
ENST00000954196
resolver
enst
ENST00000954197
resolver
genesymbol
KCNS3
resolver
hgnc
HGNC:6302
resolver
uniprot
D6W520
resolver
uniprot
O43651
resolver
uniprot
Q4ZFY1
resolver
uniprot
Q96B56
resolver
uniprot_entry
KCNS3_HUMAN
resolver
uniprot_sec
D6W520
resolver
uniprot_sec
O43651
resolver
uniprot_sec
Q4ZFY1
resolver
uniprot_sec
Q96B56
resolver
amino_acid_sequence
MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLAAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDAPEKCHELPYFNIRDIYAQRMHTFITSLSSVGIVVSDPDSTDASSIEDNEDICNTTSLENCTAK
uniprot
proteins
function
FUNCTION: Potassium channel regulatory subunit that modulates the delayed rectifier potassium channel activity of KCNB1 by namely slowing down the deactivation and inactivation time constants (PubMed:10484328). While it does not form functional channel on its own, it can form functional heterotetrameric channels with KCNB1 (PubMed:10484328). {ECO:0000269|PubMed:10484328}.
uniprot
proteins
mass_dalton
56001
uniprot
proteins
protein_family
Kv9.3/KCNS3 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
protein_family
S (TC 1.A.1.2) subfamily
uniprot
proteins
pubmed
10484328
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
22943705
uniprot
proteins
sequence_length
491
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:10484328}; Multi-pass membrane protein {ECO:0000305}. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328). {ECO:0000269|PubMed:10484328}.
uniprot
proteins
transmembrane_region
TRANSMEM 183..204; /note="Helical; Name=Segment S1"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 221..243; /note="Helical; Name=Segment S2"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 255..275; /note="Helical; Name=Segment S3"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 286..306; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 322..343; /note="Helical; Name=Segment S5"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 385..413; /note="Helical; Name=Segment S6"; /evidence="ECO:0000250|UniProtKB:P63142
uniprot
proteins