RO60
entrez
6738
canonical
uniprot
P10155
canonical
ensembl
ENSG00000116747
resolver
ensp
ENSP00000356413
resolver
ensp
ENSP00000356414
resolver
ensp
ENSP00000356415
resolver
ensp
ENSP00000356416
resolver
ensp
ENSP00000383752
resolver
ensp
ENSP00000472298
resolver
ensp
ENSP00000544724
resolver
enst
ENST00000432079
resolver
genesymbol
RO60
resolver
genesymbol_syn
SSA2
resolver
genesymbol_syn
TROVE2
resolver
hgnc
HGNC:11313
resolver
uniprot
A0A024R941
resolver
uniprot
A0A9K3Y7X9
resolver
uniprot
B2RBB9
resolver
uniprot
G5E9R9
resolver
uniprot
Q5LJ98
resolver
uniprot
Q5LJ99
resolver
uniprot
Q5LJA0
resolver
uniprot
Q86WL3
resolver
uniprot
Q86WL4
resolver
uniprot
Q92787
resolver
uniprot
Q9H1W6
resolver
uniprot_entry
G5E9R9_HUMAN
resolver
uniprot_entry
RO60_HUMAN
resolver
uniprot_sec
A0A024R941
resolver
uniprot_sec
A0A9K3Y7X9
resolver
uniprot_sec
B2RBB9
resolver
uniprot_sec
Q5LJ98
resolver
uniprot_sec
Q5LJ99
resolver
uniprot_sec
Q5LJA0
resolver
uniprot_sec
Q86WL3
resolver
uniprot_sec
Q86WL4
resolver
uniprot_sec
Q92787
resolver
uniprot_sec
Q9H1W6
resolver
amino_acid_sequence
MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI
uniprot
proteins
function
FUNCTION: RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs (PubMed:18056422, PubMed:26382853). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion (PubMed:26382853). Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853). May play roles in cilia formation and/or maintenance (By similarity). {ECO:0000250|UniProtKB:O08848, ECO:0000269|PubMed:18056422, ECO:0000269|PubMed:26382853}.
uniprot
proteins
mass_dalton
60671
uniprot
proteins
protein_family
Ro 60 kDa family
uniprot
proteins
pubmed
10545525
uniprot
proteins
pubmed
10668799
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17289661
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
18056422
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26382853
uniprot
proteins
pubmed
2649513
uniprot
proteins
pubmed
3200833
uniprot
proteins
sequence_length
538
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000269|PubMed:17289661}.
uniprot
proteins