FGGY
entrez
55277
canonical
uniprot
Q96C11
canonical
ensembl
ENSG00000172456
resolver
ensp
ENSP00000305922
resolver
ensp
ENSP00000360254
resolver
ensp
ENSP00000360256
resolver
ensp
ENSP00000360262
resolver
ensp
ENSP00000564332
resolver
ensp
ENSP00000564333
resolver
ensp
ENSP00000564336
resolver
ensp
ENSP00000564338
resolver
ensp
ENSP00000564339
resolver
ensp
ENSP00000564340
resolver
ensp
ENSP00000564342
resolver
ensp
ENSP00000564343
resolver
ensp
ENSP00000564344
resolver
ensp
ENSP00000564345
resolver
ensp
ENSP00000564346
resolver
ensp
ENSP00000564352
resolver
ensp
ENSP00000644274
resolver
ensp
ENSP00000783786
resolver
genesymbol
FGGY
resolver
hgnc
HGNC:25610
resolver
uniprot
B1AK92
resolver
uniprot
B1AK93
resolver
uniprot
B1AK94
resolver
uniprot
B2RDR8
resolver
uniprot
D3DQ56
resolver
uniprot
Q9HA63
resolver
uniprot
Q9NV20
resolver
uniprot_entry
FGGY_HUMAN
resolver
uniprot_sec
B1AK92
resolver
uniprot_sec
B1AK93
resolver
uniprot_sec
B1AK94
resolver
uniprot_sec
B2RDR8
resolver
uniprot_sec
D3DQ56
resolver
uniprot_sec
Q9HA63
resolver
uniprot_sec
Q9NV20
resolver
amino_acid_sequence
MSGGEQKPERYYVGVDVGTGSVRAALVDQSGVLLAFADQPIKNWEPQFNHHEQSSEDIWAACCVVTKKVVQGIDLNQIRGLGFDATCSLVVLDKQFHPLPVNQEGDSHRNVIMWLDHRAVSQVNRINETKHSVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKGWDDSFWKMIGLEDFVADNYSKIGNQVLPPGASLGNGLTPEAARDLGLLPGIAVAASLIDAHAGGLGVIGADVRGHGLICEGQPVTSRLAVICGTSSCHMGISKDPIFVPGVWGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFPELQVKATARCQSIYAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLKLSQDLDDLAILYLATVQAIALGTRFIIEAMEAAGHSISTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVESVLVGAAVLGACASGDFASVQEAMAKMSKVGKVVFPRLQDKKYYDKKYQVFLKLVEHQKEYLAIMNDD
uniprot
proteins
disease_involvement
DISEASE: Amyotrophic lateral sclerosis (ALS) [MIM:105400]: A neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord, resulting in fatal paralysis. Sensory abnormalities are absent. The pathologic hallmarks of the disease include pallor of the corticospinal tract due to loss of motor neurons, presence of ubiquitin-positive inclusions within surviving motor neurons, and deposition of pathologic aggregates. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of the cases. {ECO:0000269|PubMed:17671248}. Note=Disease susceptibility is associated with variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
2.7.1.47
uniprot
proteins
function
FUNCTION: Catalyzes ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate. Postulated to function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activities. Alternatively, may play a role in regulating D-ribulose 5-phosphate recycling in the pentose phosphate pathway. Can phosphorylate ribitol with low efficiency. {ECO:0000269|PubMed:27909055}.
uniprot
proteins
mass_dalton
59993
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; pentose and glucuronate interconversion. {ECO:0000305|PubMed:27909055}.
uniprot
proteins
protein_family
FGGY kinase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17671248
uniprot
proteins
pubmed
27909055
uniprot
proteins
sequence_length
551
uniprot
proteins