Actl7a
entrez
298017
canonical
uniprot
Q641W9
canonical
ensembl
ENSRNOG00000016641
resolver
ensembl
ENSRNOG00055018568
resolver
ensembl
ENSRNOG00060010472
resolver
ensembl
ENSRNOG00065015414
resolver
ensp
ENSRNOP00000022395
resolver
ensp
ENSRNOP00000102903
resolver
ensp
ENSRNOP00055025509
resolver
ensp
ENSRNOP00060013758
resolver
ensp
ENSRNOP00065020075
resolver
enst
ENSRNOT00000022395
resolver
enst
ENSRNOT00000146373
resolver
enst
ENSRNOT00055031576
resolver
enst
ENSRNOT00060017700
resolver
enst
ENSRNOT00065025566
resolver
genesymbol
Actl7a
resolver
uniprot_entry
ACL7A_RAT
resolver
amino_acid_sequence
MSLDAVWAPQTANIGDGPAKKASDQTSMQTQVLQTASLRDGPAKRAVWVRRDNAEKEEPVKSAVSKDRPRLEVTKAVVVDLGTGFCKCGFAGLPKPTHKISTTVGKPYMETAKTGDNRKETFVGRELFNPDIHLKLVNPLRHGIIVDWDTVQDIWEYLFRQEMKIAPEEHAVLVSDPPLSPHTNREKYAEMLFETFNTPAMHIAYQSRLSMYSYGRTSGLVVEVGHGVSYVVPIYEGYPLPSITGRLDYAGSDLTNYLMNLMNNCGKHFSEDHLSIVEDIKTKCCFVALDPIEEKKIPPSEHEIHYTLPDGKEIRLGQERFLCSEMFFKPSLIKSMQLGLHTQTVSCLNKCDIALKRDLMGNILLCGGSTMLRGFPNRLQKELSSMCPNDTPQVNVLPERDTAVWTGGSILASLQGFQPLWVHRLEYEEHGPFFLYRRCF
uniprot
proteins
function
FUNCTION: Essential for normal spermatogenesis and male fertility. Required for normal sperm head morphology, acroplaxome formation, acrosome attachment, and acrosome granule stability. May anchor and stabilize acrosomal adherence to the acroplaxome at least in part by facilitating the presence of F-actin in the subacrosomal space. May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis. {ECO:0000250|UniProtKB:Q9QY84}.
uniprot
proteins
mass_dalton
49568
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21278383
uniprot
proteins
sequence_length
440
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9QY84}. Golgi apparatus {ECO:0000250|UniProtKB:Q9QY84}. Cytoplasm {ECO:0000269|PubMed:21278383}. Nucleus {ECO:0000250|UniProtKB:Q9QY84}. Note=Detected at the Golgi apparatus during acrosome biogenesis. Detected at the subacrosomal layer in round spermatids. Detected in sperm head and tail. {ECO:0000250|UniProtKB:Q9QY84}.
uniprot
proteins