Mpp1
entrez
17524
canonical
uniprot
P70290
canonical
ensembl
ENSMUSG00000031402
resolver
ensp
ENSMUSP00000033775
resolver
enst
ENSMUST00000033775
resolver
genesymbol
Mpp1
resolver
uniprot
Q542P4
resolver
uniprot_entry
EM55_MOUSE
resolver
uniprot_entry
Q542P4_MOUSE
resolver
amino_acid_sequence
MTLKSSEGEGGNSMRTALSDLYLEHLLQKRNRPETSLNQSNVTTEDMYTNGSPAPGSPAHAKGQEARRVRLIQFEKITEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKGMISLKVIANQQSRLPALQMFMRAQFDYDPQKDNLIPCKEAGLKFVTGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASVAHSAPSEAPSCSPFGKKKKCKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNGLLSHNPEKFAYPAPYTTRPPKKSEEDGKEYHFISTEEMTKNISANEFLEFGSYQGNMFGTKFETVHQIHKQDKIAILDIEPQTLKTVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNSVDETLKKLQEAFDQACSSPQWVPVSWVY
uniprot
proteins
function
FUNCTION: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity. {ECO:0000269|PubMed:19897731}.
uniprot
proteins
mass_dalton
52227
uniprot
proteins
post_translational_modification
PTM: Palmitoylated. {ECO:0000250|UniProtKB:Q00013}.
uniprot
proteins
protein_family
MAGUK family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16829577
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17584769
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19897731
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8954807
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q00013}; Lipid-anchor {ECO:0000250|UniProtKB:Q00013}. Cell projection, stereocilium {ECO:0000269|PubMed:16829577, ECO:0000269|PubMed:17584769}. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (PubMed:16829577). Colocalizes with PALS1 in the retina, at the outer limiting membrane (OLM) (PubMed:17584769). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies, and at connecting cilium (CC) (PubMed:17584769). Colocalizes with NF2 in non-myelin-forming Schwann cells (By similarity). {ECO:0000250|UniProtKB:Q00013, ECO:0000269|PubMed:16829577, ECO:0000269|PubMed:17584769}.
uniprot
proteins