Ang2
entrez
11731
canonical
uniprot
Q64438
canonical
ensembl
ENSMUSG00000047894
resolver
ensp
ENSMUSP00000062902
resolver
ensp
ENSMUSP00000154100
resolver
enst
ENSMUST00000051274
resolver
enst
ENSMUST00000228835
resolver
genesymbol
Ang2
resolver
genesymbol_syn
Angrp
resolver
uniprot
G5E8D0
resolver
uniprot_entry
ANG2_MOUSE
resolver
uniprot_sec
G5E8D0
resolver
activity_regulation
ACTIVITY REGULATION: Divalent metal ions, such as Cu2+ and Zn2+, may inhibit the ribonucleolytic activity. {ECO:0000269|PubMed:23170778}.
uniprot
proteins
amino_acid_sequence
MAMSPGPLFLVFLLGLVVIPPTLSQDDSRYTKFLTQHYDAKPKGRDDRYCESMMVKRKLTSFCKDVNTFIHDTKNNIKAICGKKGSPYGRNLRISKSHFQVTTCTHKGRSPRPPCRYRASKGFRYIIIGCENGWPVHFDESFISP
uniprot
proteins
ec_number
3.1.27.-
uniprot
proteins
function
FUNCTION: Has ribonuclease activity (in vitro). Seems to lack angiogenic activity. {ECO:0000269|PubMed:8633065}.
uniprot
proteins
mass_dalton
16593
uniprot
proteins
protein_family
Pancreatic ribonuclease family
uniprot
proteins
pubmed
16045902
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
23170778
uniprot
proteins
pubmed
8530072
uniprot
proteins
pubmed
8633065
uniprot
proteins
sequence_length
145
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000250|UniProtKB:Q3TMQ6}. Secreted {ECO:0000250|UniProtKB:P10152}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P03950}. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity). {ECO:0000250|UniProtKB:P03950}.
uniprot
proteins