Lmcd1
entrez
30937
canonical
uniprot
Q8VEE1
canonical
ensembl
ENSMUSG00000057604
resolver
ensp
ENSMUSP00000032376
resolver
enst
ENSMUST00000032376
resolver
genesymbol
Lmcd1
resolver
uniprot
Q3TVW6
resolver
uniprot
Q8BVZ6
resolver
uniprot_entry
LMCD1_MOUSE
resolver
uniprot_entry
Q3TVW6_MOUSE
resolver
uniprot_entry
Q8BVZ6_MOUSE
resolver
amino_acid_sequence
MAKVAKDLNPGVQKMSLGQQQSARGVACLRCKGMCSGFEPHSWRKICKSCKCSQEEHCLSSDLDDDRKIGRLLMDSKYATLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKERQPVTGTEGALYRRRQLMHQLPIYDQDPSRCRGLVENELKAMEEFVKHYKSEALGVGEVALPGQGGLPKEENKTQEKPEGTETTAPTTNGSLGDPSKEVEYVCELCKGAAPVDSPVVYADRAGYSKQWHPTCFQCIKCSEPLVDLIYFWKDGAPWCGRHYCESVRPRCSGCDEIIFSEDYQRVEDLAWHRKHFICEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS
uniprot
proteins
function
FUNCTION: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. {ECO:0000269|PubMed:16199866, ECO:0000269|PubMed:20026769}.
uniprot
proteins
mass_dalton
40996
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16199866
uniprot
proteins
pubmed
20026769
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
365
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16199866}. Nucleus {ECO:0000269|PubMed:16199866}. Note=May shuttle between the cytoplasm and the nucleus.
uniprot
proteins