Muc20
entrez
224116
canonical
uniprot
Q8BUE7
canonical
ensembl
ENSMUSG00000035638
resolver
ensp
ENSMUSP00000041221
resolver
ensp
ENSMUSP00000110769
resolver
enst
ENSMUST00000041123
resolver
enst
ENSMUST00000115116
resolver
genesymbol
Muc20
resolver
uniprot
E9PUF1
resolver
uniprot
Q76I84
resolver
uniprot
Q8R0X0
resolver
uniprot_entry
E9PUF1_MOUSE
resolver
uniprot_entry
MUC20_MOUSE
resolver
uniprot_sec
Q76I84
resolver
uniprot_sec
Q8R0X0
resolver
amino_acid_sequence
MGSVWGLAVPLLVFCWKVGVSVSSPGLDISRSVPLVTTNNMEVSTFTQRDRPSSERAFQTTNLIQYVPLDTQTLSTESASNALSATSISSEVNSRDTQTTSFVTKTRKTHTTTPAASSLEAQTTSPNLSTLNIQITSPIASSLDAQTIFPVSLSLSTQTTSPAPSFLDTQTTSPEPSSLTTSPAPSSLITSPTPSSLTTSPAPSFLDTQTTSPAPSSLTTSPAPSSLDTQTISPIELTLKTQTISTVTETRTVSIRIPSDLTVMHTIPTETLAPSNSPRTGMSTVQTGTVWDSIEAVFDTLCTDDSSEEARKITVDLLTLAHTSTEVEYLSSESSSSSDSSAGVLSSSRVLGPDSATPAKGLVAFNITHIKLSNCITEIETTITISGAPGASLSPTEATAALFTSEILTLPPPTEAKPIFPETTSLSGILSTAGTPALATTLEGTVSTSAITESETAVAQTLTSVGTSVTVRRNPLENTSTLSIETQSHTEVLGTITVPMVAGSTMGEAASFVSFTALDSSSLSVVVTTESSATSETLTTGNTTNSSFLTESHPPFSIYSTTASTSKNPNITLTKTTASPKPPTHPTTSASTAWIRKTTKHDPGEDGGFLLVRLTVASPKDLTEHNAREKLMNQLRRELHARMPLVHMSFLSIRRG
uniprot
proteins
function
FUNCTION: May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
68720
uniprot
proteins
pubmed
14565953
uniprot
proteins
pubmed
15314156
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
656
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}. Apical cell membrane {ECO:0000250}. Basolateral cell membrane {ECO:0000250}. Cell projection, microvillus membrane {ECO:0000250}.
uniprot
proteins