TAS2R39
entrez
259285
canonical
uniprot
P59534
canonical
ensembl
ENSG00000236398
resolver
ensp
ENSP00000405095
resolver
enst
ENST00000446620
resolver
genesymbol
TAS2R39
resolver
hgnc
HGNC:18886
resolver
uniprot
A4FUI7
resolver
uniprot
Q3ZCN6
resolver
uniprot
Q645W4
resolver
uniprot_entry
T2R39_HUMAN
resolver
uniprot_sec
A4FUI7
resolver
uniprot_sec
Q3ZCN6
resolver
uniprot_sec
Q645W4
resolver
amino_acid_sequence
MLGRCFPPDTKEKQQLRMTKLCDPAESELSPFLITLILAVLLAEYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLSVSRIALQSLMMLEITISSTSLSFYSEDAVYYAFKISFIFLNFCSLWFAAWLSFFYFVKIANFSYPLFLKLRWRITGLIPWLLWLSVFISFSHSMFCINICTVYCNNSFPIHSSNSTKKTYLSEINVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTLHMGSNATGSNDPSMEAHMGAIKAISYFLILYIFNAVALFIYLSNMFDINSLWNNLCQIIMAAYPASHSILLIQDNPGLRRAWKRLQLRLHLYPKEWTL
uniprot
proteins
function
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
38626
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
11696554
uniprot
proteins
pubmed
12139982
uniprot
proteins
pubmed
12379855
uniprot
proteins
pubmed
12581520
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15496549
uniprot
proteins
sequence_length
338
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 31..51; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 75..95; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 157..177; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 206..226; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 263..283; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 292..312; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins