Fxyd4
entrez
108017
canonical
uniprot
Q9D2W0
canonical
ensembl
ENSMUSG00000004988
resolver
ensp
ENSMUSP00000005114
resolver
ensp
ENSMUSP00000144700
resolver
ensp
ENSMUSP00000145302
resolver
ensp
ENSMUSP00000342006
resolver
enst
ENSMUST00000005114
resolver
enst
ENSMUST00000203082
resolver
enst
ENSMUST00000204214
resolver
genesymbol
Fxyd4
resolver
uniprot_entry
FXYD4_MOUSE
resolver
amino_acid_sequence
MEEITCAFLLLLAGLPALEASDPVDKDSPFYYDWESLQLGGLIFGGLLCIAGIAMALSGKCKCRRTHKPSSLPGKATPLIIPGSANTC
uniprot
proteins
function
FUNCTION: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Increases the apparent affinity of the transporter for Na(+) and increases NKA activity. {ECO:0000250|UniProtKB:Q63113}.
uniprot
proteins
mass_dalton
9269
uniprot
proteins
protein_family
FXYD family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
88
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q63113}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63113}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q63113}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63113}. Note=Detected in the basolateral membrane of collecting duct principal cells. {ECO:0000250|UniProtKB:Q63113}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q63113
uniprot
proteins