Pgap1
entrez
316400
canonical
uniprot
Q765A7
canonical
ensembl
ENSRNOG00000013388
resolver
ensembl
ENSRNOG00055004570
resolver
ensembl
ENSRNOG00060023508
resolver
ensembl
ENSRNOG00065003023
resolver
ensp
ENSRNOP00000017967
resolver
ensp
ENSRNOP00055005411
resolver
ensp
ENSRNOP00060033758
resolver
ensp
ENSRNOP00065003015
resolver
enst
ENSRNOT00000017967
resolver
enst
ENSRNOT00055007247
resolver
enst
ENSRNOT00060040821
resolver
enst
ENSRNOT00065004241
resolver
genesymbol
Pgap1
resolver
uniprot_entry
PGAP1_RAT
resolver
amino_acid_sequence
MFLHSVNLWNLAFYVFMVFLATLGLWDVFFGFEENKCSMSYMFEYPEYQKIELPKKLTKRYPAYELYLYGEGSYAEEHKILPLTGIPVLFLPGNAGSYKQVRSIGSIALRKAEDIDFKYHFDFFSVNFNEELVALYGGSLQKQTKFVHECIKAILKLYKGQEFPPTSVAIIGHSMGGLVARALLTLKNFKQDLINLLVTQATPHVAPVMPLDRFITEFYMTVNNYWILNARHINLTTLSVAGGFRDYQVRSGLTFLPTLSHHTSALSVVTSAVPKTWVSTDHLSIVWCKQLQLTTIRAFFDLIDADTKQITQKSKKKLSVLNHHFIRHPAKQFEENPSIISDLTGTSMWVPVKVSRWSYVAYNESDKIYFAFPLANHRKVYTHAYCQSTMLDTNSWIFGCINSTSMCRQGVDLSWKAELLPTIKSLTLRLQDYPSLSHIVVYVPSVHGSKFVVDCEFFKKEARSIQLPVTHLFSFGLSSRKAIINTSGRYYNIELLNLGQIYQAFKVNVVSKCTGGKEEITSIYKLHIPWSYEDSLTIAQVPSSVDISLKLHVAQPENDSHVALLKMYTSSDCQYEVTIKTSFPQILGQVVRFHGGALPAYVVSSILLAYGGQLYSLLSTGFCLEYGTMLDKEAKPYKVDPFVIMIKFLLGYKWFKELWDAVLLPELDAIVLTSQSMCFPLVSLILFLFGTCTAYWSGLLSSASVQLLSSLWLALKRPAELPKDVKVMSPDLPVLTVVFLIISWTTCGALAILLSYLYYVFKVVHLQASLTTFKNNQPVNPKHSRRSEKKSNHHKDSAIQNPRLSANDAEDSLRMHSTVINLLTWVVLLSMPSLIYWSKNLRYYFKLNPDPCKPLAFLLIPAIAVLGNTHTVSIKSSKLLKTASQFPLPLAVGVIAFGSSHLYRVPCFVIIPLVFHSLCNFM
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: GPI inositol-deacylase that catalyzes the remove of the acyl chain linked to the 2-OH position of inositol ring from the GPI-anchored protein (GPI-AP) in the endoplasmic reticulum (PubMed:14734546). Initiates the post-attachment remodeling phase of GPI-AP biogenesis and participates in endoplasmic reticulum (ER)-to-Golgi transport of GPI-anchored protein (PubMed:14734546). {ECO:0000269|PubMed:14734546}.
uniprot
proteins
mass_dalton
104384
uniprot
proteins
mutagenesis
MUTAGEN 174; /note="S->A: Abolishes the inositol deacylation of GPI-anchor proteins."; /evidence="ECO:0000269|PubMed:14734546
uniprot
proteins
protein_family
GPI inositol-deacylase family
uniprot
proteins
pubmed
14734546
uniprot
proteins
pubmed
24090084
uniprot
proteins
sequence_length
922
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14734546}; Multi-pass membrane protein {ECO:0000269|PubMed:14734546}.
uniprot
proteins
transmembrane_region
TRANSMEM 12..32; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 598..618; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 642..662; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 669..689; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 695..715; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 734..754; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 817..837; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 854..874; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 895..915; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins