Dpf1
entrez
29861
canonical
uniprot
Q9QX66
canonical
ensembl
ENSMUSG00000030584
resolver
ensp
ENSMUSP00000054385
resolver
ensp
ENSMUSP00000070539
resolver
ensp
ENSMUSP00000103865
resolver
ensp
ENSMUSP00000103866
resolver
ensp
ENSMUSP00000203325
resolver
ensp
ENSMUSP00000203328
resolver
enst
ENSMUST00000108231
resolver
genesymbol
Dpf1
resolver
genesymbol_syn
Baf45b
resolver
genesymbol_syn
Neud4
resolver
uniprot
D3YY44
resolver
uniprot
Q6GTK4
resolver
uniprot
Q9QX65
resolver
uniprot
Q9QYA4
resolver
uniprot_entry
D3YY44_MOUSE
resolver
uniprot_entry
DPF1_MOUSE
resolver
uniprot_entry
Q6GTK4_MOUSE
resolver
uniprot_sec
Q9QX65
resolver
uniprot_sec
Q9QYA4
resolver
amino_acid_sequence
MATVIPSPLSLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPEGPVLEALLCAETGEKKVELKEEETIMDCQKQQLLEFPHDLEVEDLEEDIPRRKNRARGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEEHTERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAYITLT
uniprot
proteins
function
FUNCTION: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. {ECO:0000269|PubMed:17640523}.
uniprot
proteins
mass_dalton
44239
uniprot
proteins
protein_family
Requiem/DPF family
uniprot
proteins
pubmed
10602997
uniprot
proteins
pubmed
17640523
uniprot
proteins
sequence_length
387
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
uniprot
proteins