Meaf6
entrez
70088
canonical
uniprot
Q2VPQ9
canonical
ensembl
ENSMUSG00000028863
resolver
ensp
ENSMUSP00000053543
resolver
ensp
ENSMUSP00000101777
resolver
ensp
ENSMUSP00000122288
resolver
genesymbol
Meaf6
resolver
uniprot
B1ASC6
resolver
uniprot
Q9D7J5
resolver
uniprot_entry
EAF6_MOUSE
resolver
uniprot_sec
B1ASC6
resolver
uniprot_sec
Q9D7J5
resolver
amino_acid_sequence
MAMHNKTAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDTSPDFHNQENEPAQEDPEDLDGSVQGVKPQKAASSTSSGSHHSSHKKRKNKNRHRIDLKLNKKPRADY
uniprot
proteins
function
FUNCTION: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. {ECO:0000250|UniProtKB:Q9HAF1}.
uniprot
proteins
mass_dalton
21649
uniprot
proteins
protein_family
EAF6 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
191
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9HAF1}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:Q9HAF1}.
uniprot
proteins