Pde1a
entrez
18573
canonical
uniprot
Q61481
canonical
ensembl
ENSMUSG00000059173
resolver
ensp
ENSMUSP00000088260
resolver
ensp
ENSMUSP00000099711
resolver
ensp
ENSMUSP00000099712
resolver
ensp
ENSMUSP00000099713
resolver
ensp
ENSMUSP00000099715
resolver
ensp
ENSMUSP00000120188
resolver
ensp
ENSMUSP00000160024
resolver
ensp
ENSMUSP00000257545
resolver
enst
ENSMUST00000090756
resolver
genesymbol
Pde1a
resolver
uniprot
A2ASF9
resolver
uniprot
E9Q6V1
resolver
uniprot
O35388
resolver
uniprot
Q5I7S8
resolver
uniprot
Q8BRR9
resolver
uniprot
Q9JLL9
resolver
uniprot_entry
A2ASF9_MOUSE
resolver
uniprot_entry
PDE1A_MOUSE
resolver
uniprot_sec
E9Q6V1
resolver
uniprot_sec
O35388
resolver
uniprot_sec
Q5I7S8
resolver
uniprot_sec
Q8BRR9
resolver
uniprot_sec
Q9JLL9
resolver
activity_regulation
ACTIVITY REGULATION: Type I PDE are activated by the binding of calmodulin in the presence of Ca(2+). {ECO:0000269|PubMed:15901640}.; ACTIVITY REGULATION: [Isoform 2]: Activated by the binding of calmodulin in the presence of Ca(2+). {ECO:0000269|PubMed:15901640}.
uniprot
proteins
amino_acid_sequence
MGSTDTDIEELENATYKYLIGEQTEKMWQRLKGILRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKPEEKPKFRSIVHAVQAGIFVERMYRKNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILVNLSKDDWRDLRNLVIEMVLATDMSGHFQQIKNIRNSLQQPEGIDRAKTMSLILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLIEEASKSQSSNYGASSSSTMIGFHVADSLRRSNTKGSVCDGSYAPDYSLSAVDLKSFKNNLVDIIQQNKERWKELAAQGELDLHKNSEELGNTEEKHADTRP
uniprot
proteins
ec_number
3.1.4.17
uniprot
proteins
function
FUNCTION: Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. {ECO:0000269|PubMed:15901640}.
uniprot
proteins
mass_dalton
62347
uniprot
proteins
protein_family
Cyclic nucleotide phosphodiesterase family
uniprot
proteins
protein_family
PDE1 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15901640
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
545
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 2]: Cell projection, cilium, flagellum {ECO:0000269|PubMed:15901640}. Note=Concentrates in the tail of mature sperm. {ECO:0000269|PubMed:15901640}.
uniprot
proteins