EEF1AKMT3
entrez
25895
canonical
uniprot
Q96AZ1
canonical
ensembl
ENSG00000123427
resolver
ensp
ENSP00000300209
resolver
ensp
ENSP00000327425
resolver
genesymbol
EEF1AKMT3
resolver
genesymbol_syn
FAM119B
resolver
genesymbol_syn
HCA557A
resolver
genesymbol_syn
METTL21B
resolver
hgnc
HGNC:24936
resolver
uniprot
Q9H749
resolver
uniprot
Q9Y3W2
resolver
uniprot_entry
EFMT3_HUMAN
resolver
uniprot_sec
Q9H749
resolver
uniprot_sec
Q9Y3W2
resolver
amino_acid_sequence
MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Protein-lysine methyltransferase that selectively mono-, di- and trimethylates 'Lys-165' of the translation elongation factors EEF1A1 and EEF1A2 in an aminoacyl-tRNA and GTP-dependent manner. EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation. {ECO:0000269|PubMed:28108655, ECO:0000269|PubMed:28663172}.
uniprot
proteins
mass_dalton
24911
uniprot
proteins
protein_family
METTL21 family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
23349634
uniprot
proteins
pubmed
28108655
uniprot
proteins
pubmed
28663172
uniprot
proteins
sequence_length
226
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23349634, ECO:0000269|PubMed:28108655}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:28108655}.
uniprot
proteins