Cts8
entrez
56094
canonical
uniprot
Q9JI81
canonical
ensembl
ENSMUSG00000057446
resolver
ensp
ENSMUSP00000021891
resolver
enst
ENSMUST00000021891
resolver
genesymbol
Cts8
resolver
genesymbol_syn
Cts2
resolver
genesymbol_syn
Epcs68
resolver
genesymbol_syn
Epcs70
resolver
uniprot
Q6NV96
resolver
uniprot_entry
CAT8_MOUSE
resolver
uniprot_sec
Q6NV96
resolver
amino_acid_sequence
MGPAVLLAILCLGVAEVTQSSDPSLDSEWQEWKRKFNKNYSMEEEGQKRAVWEENMKLVKQHNIEYDQGKKNFTMDVNAFGDMTGEEYRKMLTDIPVPNFRKKKSIHQPIAGYLPKFVDWRKRGCVTPVKNQGTCNSCWAFSAAGAIEGQMFRKTGKLVPLSTQNLVDCSRLEGNFGCFKGSTFLALKYVWKNRGLEAESTYPYKGTDGHCRYHPERSAARITSFSFVSNSEKDLMRAVATIGPISVGIDARHKSFRLYREGIYYEPKCSSNIINHSVLVVGYGYEGKESDGNKYWLIKNSHGEQWGMNGYMKLARGRNNHCGIASYAVYPRV
uniprot
proteins
ec_number
3.4.22.-
uniprot
proteins
function
FUNCTION: Probable protease (By similarity). In placenta, plays a role in promoting giant cell differentiation (PubMed:18776147). Also plays a role in placental spiral artery remodeling by direct degradation of smooth muscle alpha-actin (PubMed:18776147). {ECO:0000250|UniProtKB:O60911, ECO:0000269|PubMed:18776147}.
uniprot
proteins
mass_dalton
37803
uniprot
proteins
protein_family
Peptidase C1 family
uniprot
proteins
pubmed
10885754
uniprot
proteins
pubmed
11829493
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18776147
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
333
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18776147}. Lysosome {ECO:0000269|PubMed:18776147}. Endosome {ECO:0000269|PubMed:18776147}. Note=Localizes to the cytoplasm with a punctate staining pattern indicative of a predominant lysosomal and endosomal localization. {ECO:0000269|PubMed:18776147}.
uniprot
proteins