G6pc3
entrez
68401
canonical
uniprot
Q6NSQ9
canonical
ensembl
ENSMUSG00000034793
resolver
ensp
ENSMUSP00000064276
resolver
ensp
ENSMUSP00000077995
resolver
enst
ENSMUST00000070334
resolver
enst
ENSMUST00000078975
resolver
genesymbol
G6pc3
resolver
genesymbol_syn
Ugrp
resolver
uniprot
Q3TND0
resolver
uniprot
Q811R8
resolver
uniprot_entry
G6PC3_MOUSE
resolver
uniprot_sec
Q3TND0
resolver
uniprot_sec
Q811R8
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by vanadate. {ECO:0000269|PubMed:15661744}.
uniprot
proteins
amino_acid_sequence
MESTLSAGIIMAEALQNRLPGLENMWLWVTFLGDPKNLFQFCFPAAYYASRRLGISVLWITFIAEWLNLVFKWFLFGDRPFWWVHESGYSTQTPIQIHQFPSSCETGPGSPSGHCMITGAALWPVMTAISSQVASRSRSPWVRVIPGLAYCTFLLAVGLSRVFLLAHFPHQVLGGLIVGAALGWLMSPRVPMERELSFYGLTALALMLGASLMYWTLFTLGLDLSWSINLASKWCERPEWVHMDSRPFASLSRDSGSALGLGIALHTPCYAQIRRAHLGNGQKIACFVLAMGLLVFLEWLGYPPQISLFYIFNFLKYTLWPCLVLALVPWVVHTLSDQEAPPIRSS
uniprot
proteins
ec_number
3.1.3.9
uniprot
proteins
function
FUNCTION: Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function. {ECO:0000269|PubMed:15087461, ECO:0000269|PubMed:15661744, ECO:0000269|PubMed:17023421, ECO:0000269|PubMed:17318259}.
uniprot
proteins
mass_dalton
38782
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
uniprot
proteins
protein_family
Glucose-6-phosphatase family
uniprot
proteins
pubmed
14765991
uniprot
proteins
pubmed
15087461
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15661744
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17023421
uniprot
proteins
pubmed
17318259
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
346
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 57..77; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 109..129; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..159; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 168..186; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 198..218; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 255..273; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 284..304; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins