Pde1b
entrez
18574
canonical
uniprot
Q01065
canonical
ensembl
ENSMUSG00000022489
resolver
ensp
ENSMUSP00000023132
resolver
ensp
ENSMUSP00000153722
resolver
ensp
ENSMUSP00000153865
resolver
enst
ENSMUST00000023132
resolver
enst
ENSMUST00000226468
resolver
enst
ENSMUST00000227955
resolver
genesymbol
Pde1b
resolver
genesymbol_syn
Pde1b1
resolver
uniprot
A0A2I3BPC1
resolver
uniprot
A0A2I3BPP2
resolver
uniprot
O35384
resolver
uniprot
Q6PDS5
resolver
uniprot
Q9DBS6
resolver
uniprot_entry
A0A2I3BPC1_MOUSE
resolver
uniprot_entry
A0A2I3BPP2_MOUSE
resolver
uniprot_entry
PDE1B_MOUSE
resolver
uniprot_entry
Q6PDS5_MOUSE
resolver
uniprot_entry
Q9DBS6_MOUSE
resolver
uniprot_sec
O35384
resolver
activity_regulation
ACTIVITY REGULATION: Type I PDE are activated by the binding of calmodulin in the presence of Ca(2+). {ECO:0000250|UniProtKB:Q01064}.
uniprot
proteins
amino_acid_sequence
MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLEYTASLLEAVYIDETRQILDTEDELRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVHNCLKNLDLWCFDVFSLNRAADDHALRTIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQDDEMNIFINLTKDEFAELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADDDSKPKSQPSFQWRQPSLDVDVGDPNPDVVSFRATWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPSSPAEDEHNQNGNLD
uniprot
proteins
ec_number
3.1.4.17
uniprot
proteins
function
FUNCTION: Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate. {ECO:0000250|UniProtKB:Q01064}.
uniprot
proteins
mass_dalton
61226
uniprot
proteins
protein_family
Cyclic nucleotide phosphodiesterase family
uniprot
proteins
protein_family
PDE1 subfamily
uniprot
proteins
pubmed
1326532
uniprot
proteins
pubmed
1332068
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9657856
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q01064}.
uniprot
proteins