Q62809
uniprot
Q62809
canonical
amino_acid_sequence
GGGGGPAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWARYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
uniprot
proteins
function
FUNCTION: Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (By similarity). Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity). {ECO:0000250|UniProtKB:P97466, ECO:0000250|UniProtKB:Q13253}.
uniprot
proteins
mass_dalton
16139
uniprot
proteins
protein_family
Noggin family
uniprot
proteins
pubmed
7666191
uniprot
proteins
sequence_length
144
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins