Abhd17a
entrez
299617
canonical
uniprot
Q5XIJ5
canonical
ensembl
ENSRNOG00055032198
resolver
ensembl
ENSRNOG00060023499
resolver
ensembl
ENSRNOG00065018452
resolver
ensp
ENSRNOP00055045858
resolver
ensp
ENSRNOP00060033656
resolver
ensp
ENSRNOP00065024658
resolver
enst
ENSRNOT00055055627
resolver
enst
ENSRNOT00060040715
resolver
enst
ENSRNOT00065030956
resolver
genesymbol
Abhd17a
resolver
uniprot_entry
AB17A_RAT
resolver
amino_acid_sequence
MNGLSVSELCCLFCCPPCPGRIAAKLAFLPPEPTYSLVPEPEPGPGGAGAAPSGPLRTSAATPGRWKIHLTERADFQYGQRELDTIEVFVTKSARANRIACMYVRCVPGARYTVLFSHGNAVDLGQMCSFYVGLGTRIGCNIFSYDYSGYGISSGRPSEKNLYADIDAAWQALRTRYGISPDSIILYGQSIGTVPTVDLASRYECAAVVLHSPLTSGMRVAFPDTKKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALYERCPKAVEPLWVEGAGHNDIELYSQYLERLRRFISQELPSQRT
uniprot
proteins
ec_number
3.1.2.22
uniprot
proteins
function
FUNCTION: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (PubMed:27307232). Has depalmitoylating activity towards NRAS (By similarity). Has depalmitoylating activity towards DLG4/PSD95 (PubMed:27307232). May have depalmitoylating activity towards MAP6 (PubMed:28521134). {ECO:0000250|UniProtKB:Q96GS6, ECO:0000269|PubMed:27307232, ECO:0000305|PubMed:28521134}.
uniprot
proteins
mass_dalton
33994
uniprot
proteins
post_translational_modification
PTM: Palmitoylated on cysteine residues located in a cysteine cluster at the N-terminus which promotes membrane localization. Palmitoylation is required for post-synaptic localization and for depalmitoylating activity towards DLG4/PSD95. {ECO:0000250|UniProtKB:Q7M759}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
ABHD17 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27307232
uniprot
proteins
pubmed
28521134
uniprot
proteins
sequence_length
310
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:27307232}; Lipid-anchor {ECO:0000250|UniProtKB:Q96GS6}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96GS6}. Recycling endosome membrane {ECO:0000269|PubMed:27307232}; Lipid-anchor {ECO:0000250|UniProtKB:Q96GS6}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96GS6}. Cell projection, dendritic spine {ECO:0000269|PubMed:27307232}. Postsynaptic density membrane {ECO:0000269|PubMed:27307232}.
uniprot
proteins