MPRIP
entrez
23164
canonical
uniprot
Q6WCQ1
canonical
ensembl
ENSG00000133030
resolver
ensp
ENSP00000342379
resolver
ensp
ENSP00000379156
resolver
ensp
ENSP00000498253
resolver
ensp
ENSP00000618313
resolver
ensp
ENSP00000708700
resolver
ensp
ENSP00000708708
resolver
enst
ENST00000651222
resolver
genesymbol
MPRIP
resolver
genesymbol_syn
KIAA0864
resolver
genesymbol_syn
MRIP
resolver
genesymbol_syn
RHOIP3
resolver
hgnc
HGNC:30321
resolver
uniprot
A0A494BZV2
resolver
uniprot
Q3KQZ5
resolver
uniprot
Q5FB94
resolver
uniprot
Q6DHW2
resolver
uniprot
Q7Z5Y2
resolver
uniprot
Q8N236
resolver
uniprot
Q8N390
resolver
uniprot
Q96G40
resolver
uniprot_entry
A0A494BZV2_HUMAN
resolver
uniprot_entry
MPRIP_HUMAN
resolver
uniprot_entry
Q8N236_HUMAN
resolver
uniprot_sec
Q3KQZ5
resolver
uniprot_sec
Q5FB94
resolver
uniprot_sec
Q6DHW2
resolver
uniprot_sec
Q7Z5Y2
resolver
uniprot_sec
Q8N390
resolver
uniprot_sec
Q96G40
resolver
amino_acid_sequence
MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEGRTGQKFSLCILTPEKEHFIRAETKEIVSGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTTKSTLWQEEMRTKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESKEEESAMSSDRMDCGRKVRVESGYFSLEKTKQDLKAEEQQLPPPLSPPSPSTPNHRRSQVIEKFEALDIEKAEHMETNAVGPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSVTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQEAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPEAEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVEIEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPDSATVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSVIEQVSWDT
uniprot
proteins
function
FUNCTION: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. {ECO:0000250|UniProtKB:P97434, ECO:0000269|PubMed:15545284, ECO:0000269|PubMed:16257966}.
uniprot
proteins
mass_dalton
116533
uniprot
proteins
pubmed
14506264
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15545284
uniprot
proteins
pubmed
16257966
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
1025
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14506264, ECO:0000269|PubMed:16257966}. Note=Colocalizes with F-actin.
uniprot
proteins