Chordc1
entrez
315447
canonical
uniprot
D4A4T9
canonical
ensembl
ENSRNOG00000026643
resolver
ensp
ENSRNOP00000030171
resolver
enst
ENSRNOT00000030569
resolver
genesymbol
Chordc1
resolver
uniprot_entry
CHRD1_RAT
resolver
amino_acid_sequence
MALLCYNRGCGQRFDPEANADDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEEDKKEEDSDEIKIGTSCKNGGCSKTYQGLQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTRGKHVWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVEANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPTTKKQEKQKDIAD
uniprot
proteins
function
FUNCTION: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling (By similarity). Involved in stress response. Prevents tumorigenesis (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q9UHD1}.
uniprot
proteins
mass_dalton
37362
uniprot
proteins
sequence_length
331
uniprot
proteins