Fbp2
entrez
14120
canonical
uniprot
P70695
canonical
ensembl
ENSMUSG00000021456
resolver
ensp
ENSMUSP00000021907
resolver
enst
ENSMUST00000021907
resolver
genesymbol
Fbp2
resolver
uniprot
Q3TKP4
resolver
uniprot
Q91X26
resolver
uniprot
Q9JK01
resolver
uniprot
Q9JK02
resolver
uniprot
Q9JK03
resolver
uniprot
Q9JK04
resolver
uniprot
Q9JK05
resolver
uniprot
Q9JK06
resolver
uniprot
Q9JK07
resolver
uniprot
Q9JK08
resolver
uniprot
Q9JK09
resolver
uniprot
Q9QXB4
resolver
uniprot
Q9QXB5
resolver
uniprot
Q9QXB6
resolver
uniprot
Q9QXD7
resolver
uniprot_entry
F16P2_MOUSE
resolver
uniprot_entry
Q3TKP4_MOUSE
resolver
uniprot_sec
Q91X26
resolver
uniprot_sec
Q9JK01
resolver
uniprot_sec
Q9JK02
resolver
uniprot_sec
Q9JK03
resolver
uniprot_sec
Q9JK04
resolver
uniprot_sec
Q9JK05
resolver
uniprot_sec
Q9JK06
resolver
uniprot_sec
Q9JK07
resolver
uniprot_sec
Q9JK08
resolver
uniprot_sec
Q9JK09
resolver
uniprot_sec
Q9QXB4
resolver
uniprot_sec
Q9QXB5
resolver
uniprot_sec
Q9QXB6
resolver
uniprot_sec
Q9QXD7
resolver
activity_regulation
ACTIVITY REGULATION: Subject to complex allosteric regulation. The enzyme can assume an active R-state, or an inactive T-state. Intermediate conformations may exist. AMP acts as an allosteric inhibitor. Fructose 2,6-bisphosphate acts as a competitive inhibitor. Strongly inhibited by Ca(2+) (By similarity). {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLANLYGISGSVNVTGDEVKKLDVLSNSLVINMLQSSYSTCVLVSEENKEAVITAQERRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTTEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVRIKKKGKIFSLNEGYAKYFDAATAEYVQKKKFPEDGSEPYGARYVGSMVADVHRTLVYGGIFMYPANQKSPNGKLRLLYECNPVAYIIEQAGGMATTGTQPVLDVKPESIHQRVPLILGSPEDVQEYLSCVQRNQAGR
uniprot
proteins
ec_number
3.1.3.11
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. {ECO:0000269|PubMed:8034042}.
uniprot
proteins
mass_dalton
36947
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
uniprot
proteins
protein_family
FBPase class 1 family
uniprot
proteins
pubmed
10773464
uniprot
proteins
pubmed
11250076
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8034042
uniprot
proteins
sequence_length
339
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration. In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase. Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration. {ECO:0000250}.
uniprot
proteins