HEYL
entrez
26508
canonical
uniprot
Q9NQ87
canonical
ensembl
ENSG00000163909
resolver
ensp
ENSP00000361943
resolver
enst
ENST00000372852
resolver
genesymbol
HEYL
resolver
genesymbol_syn
BHLHB33
resolver
genesymbol_syn
HRT3
resolver
hgnc
HGNC:4882
resolver
uniprot
B4DU20
resolver
uniprot
Q5TG99
resolver
uniprot_entry
B4DU20_HUMAN
resolver
uniprot_entry
HEYL_HUMAN
resolver
uniprot_sec
Q5TG99
resolver
amino_acid_sequence
MKRPKEPSGSDGESDGPIDVGQEGQLSQMARPLSTPSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSSPAYPIPALRTAPLRRATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTPPGPTGSAAYVAVPTPNSSSPGPAGRPAGAMLYHSWVSEITEIGAF
uniprot
proteins
function
FUNCTION: Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. {ECO:0000250, ECO:0000269|PubMed:15485867}.
uniprot
proteins
mass_dalton
35087
uniprot
proteins
protein_family
HEY family
uniprot
proteins
pubmed
10860664
uniprot
proteins
pubmed
10964718
uniprot
proteins
pubmed
11095750
uniprot
proteins
pubmed
15485867
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
sequence_length
328
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
uniprot
proteins