AMDHD2
entrez
51005
canonical
uniprot
Q9Y303
canonical
ensembl
ENSG00000162066
resolver
ensp
ENSP00000293971
resolver
ensp
ENSP00000307481
resolver
ensp
ENSP00000391596
resolver
ensp
ENSP00000498048
resolver
enst
ENST00000648227
resolver
genesymbol
AMDHD2
resolver
hgnc
HGNC:24262
resolver
uniprot
A0A3B3IU33
resolver
uniprot
B4DL77
resolver
uniprot
Q8WV54
resolver
uniprot_entry
A0A3B3IU33_HUMAN
resolver
uniprot_entry
NAGA_HUMAN
resolver
uniprot_sec
B4DL77
resolver
uniprot_sec
Q8WV54
resolver
amino_acid_sequence
MRGEQGAAGARVLQFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGGRILAPGFIDVQINGGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHKVVPQIPVKSGGPHGAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDNVRIVTLAPELGRSHEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPFHHRDPGIVGLLTSDRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALGLGNGRHTLGQQEVEVDGLTAYVAGTKTLSGSIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVLDDSLHVQATYISGELVWQADAARQ
uniprot
proteins
ec_number
3.5.1.25
uniprot
proteins
function
FUNCTION: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. {ECO:0000269|PubMed:22692205}.
uniprot
proteins
mass_dalton
43748
uniprot
proteins
pathway_participation
PATHWAY: Amino-sugar metabolism; N-acetylneuraminate degradation. {ECO:0000269|PubMed:22692205}.
uniprot
proteins
protein_family
Metallo-dependent hydrolases superfamily
uniprot
proteins
protein_family
NagA family
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22692205
uniprot
proteins
sequence_length
409
uniprot
proteins