SRM
entrez
6723
canonical
uniprot
P19623
canonical
ensembl
ENSG00000116649
resolver
ensp
ENSP00000366156
resolver
enst
ENST00000376957
resolver
genesymbol
SRM
resolver
genesymbol_syn
SPS1
resolver
genesymbol_syn
SRML1
resolver
hgnc
HGNC:11296
resolver
uniprot
B1AKP9
resolver
uniprot
Q15511
resolver
uniprot_entry
SPEE_HUMAN
resolver
uniprot_sec
B1AKP9
resolver
uniprot_sec
Q15511
resolver
activity_regulation
ACTIVITY REGULATION: The activity is thought to be regulated mainly by the availability of decarboxylated S-adenosylmethionine.
uniprot
proteins
amino_acid_sequence
MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDVS
uniprot
proteins
ec_number
2.5.1.16
uniprot
proteins
function
FUNCTION: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine. {ECO:0000269|PubMed:17585781}.
uniprot
proteins
mass_dalton
33825
uniprot
proteins
pathway_participation
PATHWAY: Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.
uniprot
proteins
protein_family
Spermidine/spermine synthase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17585781
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
2069720
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
2344393
uniprot
proteins
sequence_length
302
uniprot
proteins