Slc7a3
entrez
11989
canonical
uniprot
P70423
canonical
ensembl
ENSMUSG00000031297
resolver
ensp
ENSMUSP00000073582
resolver
ensp
ENSMUSP00000098914
resolver
ensp
ENSMUSP00000109339
resolver
ensp
ENSMUSP00000214225
resolver
enst
ENSMUST00000073927
resolver
enst
ENSMUST00000101362
resolver
enst
ENSMUST00000113710
resolver
genesymbol
Slc7a3
resolver
genesymbol_syn
Atrc3
resolver
genesymbol_syn
Cat3
resolver
uniprot
B1AVE2
resolver
uniprot_entry
CTR3_MOUSE
resolver
uniprot_sec
B1AVE2
resolver
amino_acid_sequence
MLWQALRRFGQKLVRRRVLELGMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISRTLKGTILLKMPHVLAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLSFVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVSSALTLMMPYYKLHPESPLPEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSICVLILRYQPDQEMKSVEEEMELQEETLEAEKLTVQALFCPVNSIPTLLSGRVVYVCSSLLAVLLTVLCLVLTWWTTPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGIWMLIGFAIYFGYGIQHSMKEVKNHQTLPKTRAQTIDLDLTTSCVHSI
uniprot
proteins
function
FUNCTION: Uniporter that mediates the uptake of cationic L-amino acids such as L-arginine, L-lysine and L-ornithine (PubMed:9334265). The transport is sodium ions- and pH-independent, moderately trans-stimulated and is mediated by passive diffusion (PubMed:9334265). {ECO:0000269|PubMed:9334265}.
uniprot
proteins
mass_dalton
67460
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q8WY07}.
uniprot
proteins
protein_family
Amino acid-polyamine-organocation (APC) superfamily
uniprot
proteins
protein_family
Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
9334265
uniprot
proteins
sequence_length
618
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 37..57; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 62..82; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 108..128; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 163..183; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 192..212; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 245..265; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 286..306; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 336..356; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 381..401; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 407..427; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 475..495; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 507..527; /note="Helical; Name=12"; /evidence="ECO:0000255"; TRANSMEM 540..560; /note="Helical; Name=13"; /evidence="ECO:0000255"; TRANSMEM 569..589; /note="Helical; Name=14"; /evidence="ECO:0000255
uniprot
proteins