Q6P6L0
uniprot
Q6P6L0
canonical
amino_acid_sequence
MRSRSSNAEGSAPKQIPRHSKFQDSIQDMKHRTHKKDPSCESEGVLPRPVSEKSHTGKGHHTEDLSRDDLLFLLSILEGELQARDEVIGILRAEKIDLALLEAQYGFVTPKKVLEALQRDAFQAKSAPWQEDIYEKPMNELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNGRRISDPQVFSKEVQTEAADSEPPDYKSLIPLERAVINGQFYEENEDQDDDPNEEESVLSFRCSQSSSLPMNRKLWIPWMKSKEGHPQNGKIQTKSNGNFVQPGDLVLSHTPGQPLHIKVTPDHIQNTATLEITSPTTESPHSYTSTAVIPNCGTPKQRITILQNASITPIKSKSSTESLMNLEQSMSPVTMATFARAQTPESCGSVTPERTMSPIQVLAMTGSPSSPEQGCSPEPIEISAKHAIFRVSPDRQSSWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVAGPMRPASPSAPLQDNRTQGLTNGALNKTTNKVTSSITITPTATPLPRQSQITVSNIYN
uniprot
proteins
function
FUNCTION: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
129772
uniprot
proteins
protein_family
FILIP1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1131
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins