EFNA3
entrez
1944
canonical
uniprot
P52797
canonical
ensembl
ENSG00000143590
resolver
ensp
ENSP00000357393
resolver
genesymbol
EFNA3
resolver
genesymbol_syn
EFL2
resolver
genesymbol_syn
EPLG3
resolver
genesymbol_syn
LERK3
resolver
hgnc
HGNC:3223
resolver
uniprot
B7ZAD3
resolver
uniprot
D3DV85
resolver
uniprot
Q0VGC9
resolver
uniprot
Q5SR70
resolver
uniprot_entry
EFNA3_HUMAN
resolver
uniprot_sec
B7ZAD3
resolver
uniprot_sec
D3DV85
resolver
uniprot_sec
Q0VGC9
resolver
uniprot_sec
Q5SR70
resolver
amino_acid_sequence
MAAAPLLLLLLLVPVPLLPLLAQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSRNGYRTCNASQGFKRWECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYISTPTHNLHWKCLRMKVFVCCASTSHSGEKPVPTLPQFTMGPNVKINVLEDFEGENPQVPKLEKSISGTSPKREHLPLAVGIAFFLMTFLAS
uniprot
proteins
function
FUNCTION: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
26350
uniprot
proteins
protein_family
Ephrin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
7838529
uniprot
proteins
pubmed
7973638
uniprot
proteins
sequence_length
238
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
uniprot
proteins