Defb1
entrez
83687
canonical
uniprot
O89117
canonical
ensembl
ENSRNOG00000013768
resolver
ensembl
ENSRNOG00055008262
resolver
ensembl
ENSRNOG00060023759
resolver
ensembl
ENSRNOG00065008999
resolver
ensp
ENSRNOP00000018428
resolver
ensp
ENSRNOP00055011204
resolver
ensp
ENSRNOP00060034063
resolver
ensp
ENSRNOP00065010770
resolver
enst
ENSRNOT00000018427
resolver
enst
ENSRNOT00055013977
resolver
enst
ENSRNOT00060041134
resolver
enst
ENSRNOT00065014374
resolver
genesymbol
Defb1
resolver
uniprot_entry
DEFB1_RAT
resolver
amino_acid_sequence
MKTHYFLLVMLFFLFSQMELGAGILTSLGRRTDQYRCLQNGGFCLRSSCPSHTKLQGTCKPDKPNCCRS
uniprot
proteins
function
FUNCTION: Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. {ECO:0000250|UniProtKB:P60022}.
uniprot
proteins
mass_dalton
7837
uniprot
proteins
protein_family
Beta-defensin family
uniprot
proteins
pubmed
10456937
uniprot
proteins
sequence_length
69
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P60022}. Membrane {ECO:0000250|UniProtKB:P60022}. Note=Associates with tumor cell membrane-derived microvesicles. {ECO:0000250|UniProtKB:P60022}.
uniprot
proteins