Trim60
entrez
234329
canonical
uniprot
Q8VI40
canonical
ensembl
ENSMUSG00000053490
resolver
ensp
ENSMUSP00000040299
resolver
enst
ENSMUST00000048565
resolver
genesymbol
Trim60
resolver
genesymbol_syn
2czf45
resolver
genesymbol_syn
Rnf33
resolver
uniprot
Q3UX74
resolver
uniprot_entry
TRI60_MOUSE
resolver
uniprot_sec
Q3UX74
resolver
amino_acid_sequence
MDSTALKILQDKCICYICSDFMEDPVTSRCGHNFCFACLRLLWDDLQGNIFCPVCQTPFPPKSFSRNYQFRNMTETIRLLQKRQSKRKRQEEHTVCPKHDQPLVLFCVRDRDVLCTQCSLSVEHQGHYTCPIKKASSYHRKVLESAIATLKFGVKQVEEKLAVQHRRVLGLREEAQYQKIEIRYEIGQIKLFLQSEYEAHLNESHMEELRSFSELNGYLETLLDHVSTAKDLLKEVEAIHERSDVTLLRAYHKLQNLKSPKPWLFRTKQYGLSLPAQYSGLSRIIKQFQADVTFDRDTAHPQLVISEDRKSVFYKEAWPCVCASPQKFHLWPALLGCKGFDSGRQYWEVKVGDKPRWTLGVCQAHFSGDWSNQSSGFWAIGRYAENSYVTYGPLRTEFLPVVRPSKVGIFLDYELGELSFYNMNDRSLLYTFRNSFTSTLWPYFYIGTDSESLEILTHPTPDTGSY
uniprot
proteins
function
FUNCTION: E3 SUMO-protein ligase that mediates SUMOylation of TAB2 leading to inhibition of NF-kappa-B and MAPK pathways by suppressing the TRAF6/TAB2/TAK1 complex. {ECO:0000269|PubMed:33184450}.
uniprot
proteins
mass_dalton
54199
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
11424210
uniprot
proteins
pubmed
12160726
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
33184450
uniprot
proteins
sequence_length
466
uniprot
proteins