Cep120
entrez
225523
canonical
uniprot
Q7TSG1
canonical
ensembl
ENSMUSG00000048799
resolver
ensp
ENSMUSP00000062433
resolver
ensp
ENSMUSP00000205941
resolver
ensp
ENSMUSP00000205944
resolver
genesymbol
Cep120
resolver
genesymbol_syn
Ccdc100
resolver
uniprot
Q80Y93
resolver
uniprot
Q80ZQ2
resolver
uniprot
Q8BG01
resolver
uniprot
Q8C580
resolver
uniprot
Q8C8B6
resolver
uniprot
Q8CAF2
resolver
uniprot_entry
CE120_MOUSE
resolver
uniprot_sec
Q80Y93
resolver
uniprot_sec
Q80ZQ2
resolver
uniprot_sec
Q8BG01
resolver
uniprot_sec
Q8C580
resolver
uniprot_sec
Q8C8B6
resolver
uniprot_sec
Q8CAF2
resolver
amino_acid_sequence
MVPKSDQLLIVVSILEGRHFPKRPKHLLVVEAKFDGEQLATDPVDHTDQPEFATELAWEIDRKVLHQHRLQRTPIKLQCFALDPQTSAKETVGYIVLDLRTAQETKQAPKWYQLLSNKYTKFKAEVQISLTLETDTKAQVDSYKAKAAPPRDGKVLASLAGVDPKDIVAVLNEEGGYHQIGPAEHCTDPFILSVTIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFSDLINPNFEPERASVRIRSSVEILRVYLALHSKLQIHLCCGDQSLGSTEIPLNGLLKKGSTEINQHPVTVEGAFTLDPPNRAKQKLAPVPLDLAPTVGVSVALQREGIDSQSLIELKTQNGHEAEHSQKRVLTPIKEKTLTGPKSPRESPAPPPPPNQTPPTKDDATESEVESLQYDKDPKPTVKGIGSVPASLAQPEATCGASEVVTSGQKIAVPAASHHFCFSVDLRSVHDLELSFPVNCILRYSYPFFGSAAPIMTNPPVEVRKNMEVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDKMSKDLLLGVARIQLSNILSSEKTRFLGANGEQCWRQTYSESVPVIAAQGSNNRILDLSYTMTLEDYGLVKMREIFVSESSQGVPAVDQKPSSPPPAPCPSEIQMEPRETLEYKAALELEMWKEMQEDIFESQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYSILEGKLQKALTELETREQQLASAEAELQRERKELQLERERNLQELQDSVRRARDDCVYQVELERLKLKQLEEDKQRLQQQLNDAGNKYKTLEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKETVRTEQQELLDIRNELNRLRQQEQNQYQDCKEIASGKLGSPRGSGLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREVLTKNSAS
uniprot
proteins
function
FUNCTION: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner (By similarity). {ECO:0000250|UniProtKB:Q8N960, ECO:0000269|PubMed:17920017, ECO:0000269|PubMed:20360068, ECO:0000269|PubMed:25251415}.
uniprot
proteins
mass_dalton
112579
uniprot
proteins
protein_family
CEP120 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17920017
uniprot
proteins
pubmed
20360068
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25251415
uniprot
proteins
sequence_length
988
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17920017}. Note=Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. {ECO:0000269|PubMed:17920017}.
uniprot
proteins