Cfap126
entrez
75472
canonical
uniprot
Q6P8X9
canonical
ensembl
ENSMUSG00000026649
resolver
ensp
ENSMUSP00000027959
resolver
ensp
ENSMUSP00000114967
resolver
ensp
ENSMUSP00000123188
resolver
enst
ENSMUST00000027959
resolver
genesymbol
Cfap126
resolver
genesymbol_syn
Fltp
resolver
uniprot
Q9DAJ1
resolver
uniprot_entry
FLTOP_MOUSE
resolver
uniprot_sec
Q9DAJ1
resolver
amino_acid_sequence
MATNYSANQYEKAYLPTYLQNWSPARPTKEKIAAHEGYTQIIANDRGHLLPSVPRSKASPWGSFMGTWQMPLKIPPAKVTLTARTTTAADNLTKWIHKNPDLLNACNGLRPEISGKPFDPDSQTKQKKSVTKTVQQAPNPTIIPSSPVIQGDNPDEPQSSHPSAGHTPGPQTPVNSPNNPPPSPCKSTK
uniprot
proteins
function
FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme (PubMed:25296022, PubMed:37295417, PubMed:37865089, PubMed:37989994). Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells (PubMed:25296022). Regulates basal body docking and cilia formation in multiciliated lung cells (PubMed:25296022). Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear (By similarity). {ECO:0000250|UniProtKB:Q5VTH2, ECO:0000269|PubMed:25296022, ECO:0000269|PubMed:37295417, ECO:0000269|PubMed:37865089, ECO:0000269|PubMed:37989994}.
uniprot
proteins
mass_dalton
20550
uniprot
proteins
protein_family
Flattop family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
22153975
uniprot
proteins
pubmed
25296022
uniprot
proteins
pubmed
37295417
uniprot
proteins
pubmed
37865089
uniprot
proteins
pubmed
37989994
uniprot
proteins
sequence_length
189
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:25296022}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:25296022}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37295417, ECO:0000269|PubMed:37865089, ECO:0000269|PubMed:37989994}. Apical cell membrane {ECO:0000269|PubMed:25296022}. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells. {ECO:0000250|UniProtKB:Q3SZT6, ECO:0000269|PubMed:25296022}.
uniprot
proteins