CENPV
entrez
201161
canonical
uniprot
Q7Z7K6
canonical
ensembl
ENSG00000166582
resolver
ensp
ENSP00000299736
resolver
genesymbol
CENPV
resolver
genesymbol_syn
PRR6
resolver
hgnc
HGNC:29920
resolver
uniprot
B2RPK2
resolver
uniprot
Q3L8N5
resolver
uniprot
Q8NFH6
resolver
uniprot_entry
CENPV_HUMAN
resolver
uniprot_sec
B2RPK2
resolver
uniprot_sec
Q3L8N5
resolver
uniprot_sec
Q8NFH6
resolver
amino_acid_sequence
MRRSRSSAAAKLRGQKRSGASGASAAPAASAAAALAPSATRTRRSASQAGSKSQAVEKPPSEKPRLRRSSPRAQEEGPGEPPPPELALLPPPPPPPPTPATPTSSASNLDLGEQRERWETFQKRQKLTSEGAAKLLLDTFEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNRHFIVPASRFKLLKGAEHITTYTFNTHKAQHTFCKRCGVQSFYTPRSNPGGFGIAPHCLDEGTVRSMVTEEFNGSDWEKAMKEHKTIKNMSKE
uniprot
proteins
function
FUNCTION: Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis. {ECO:0000269|PubMed:18772885}.
uniprot
proteins
mass_dalton
29946
uniprot
proteins
mutagenesis
MUTAGEN 172; /note="C->A: Abolishes chromatin hypercondensation phenotype induced by overexpression of wild-type protein; when associated with A-177."; /evidence="ECO:0000269|PubMed:18772885"; MUTAGEN 174; /note="C->A: Abolishes chromatin hypercondensation phenotype induced by overexpression of wild-type protein."; /evidence="ECO:0000269|PubMed:18772885"; MUTAGEN 177; /note="C->A: Abolishes chromatin hypercondensation phenotype induced by overexpression of wild-type protein; when associated with A-172."; /evidence="ECO:0000269|PubMed:18772885
uniprot
proteins
protein_family
Gfa family
uniprot
proteins
pubmed
12196509
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18772885
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
275
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore {ECO:0000269|PubMed:18772885}. Nucleus {ECO:0000269|PubMed:12196509}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18772885}. Note=Enriched at the nuclear periphery and around the nucleolus (PubMed:12196509). In mitotic cells, localizes to kinetochores from prometaphase to metaphase (PubMed:18772885). At anaphase onset, transfers to the spindle midzone and then to the mid-body in telophase and cytokinesis (PubMed:18772885).
uniprot
proteins