TAF5
entrez
6877
canonical
uniprot
Q15542
canonical
ensembl
ENSG00000148835
resolver
ensp
ENSP00000358854
resolver
ensp
ENSP00000510076
resolver
genesymbol
TAF5
resolver
genesymbol_syn
TAF2D
resolver
hgnc
HGNC:11539
resolver
uniprot
A8K5B4
resolver
uniprot
B2RMR0
resolver
uniprot
B7ZKJ6
resolver
uniprot
Q53EM4
resolver
uniprot
Q5SYD5
resolver
uniprot
Q86UZ7
resolver
uniprot
Q9Y4K5
resolver
uniprot_entry
TAF5_HUMAN
resolver
uniprot_sec
A8K5B4
resolver
uniprot_sec
B2RMR0
resolver
uniprot_sec
B7ZKJ6
resolver
uniprot_sec
Q53EM4
resolver
uniprot_sec
Q5SYD5
resolver
uniprot_sec
Q86UZ7
resolver
uniprot_sec
Q9Y4K5
resolver
amino_acid_sequence
MAALAEEQTEVAVKLEPEGPPTLLPPQAGDGAGEGSGGTTNNGPNGGGGNVAASSSTGGDGGTPKPTVAVSAAAPAGAAPVPAAAPDAGAPHDRQTLLAVLQFLRQSKLREAEEALRREAGLLEEAVAGSGAPGEVDSAGAEVTSALLSRVTASAPGPAAPDPPGTGASGATVVSGSASGPAAPGKVGSVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGENEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVRLGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ
uniprot
proteins
function
FUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473, PubMed:8758937, PubMed:8942982, PubMed:9045704). The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C (PubMed:33795473). TAF5 is involved in two modules of TFIID, in TFIID-A together with TAF3 and TBP, and in TFIID-B with TAF8 (PubMed:33795473). Involved in contacts between TFIID and TFIIF in the PIC (PubMed:33795473). {ECO:0000269|PubMed:33795473, ECO:0000269|PubMed:8758937, ECO:0000269|PubMed:8942982, ECO:0000269|PubMed:9045704}.
uniprot
proteins
mass_dalton
86830
uniprot
proteins
protein_family
WD repeat TAF5 family
uniprot
proteins
pubmed
10373431
uniprot
proteins
pubmed
12601814
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17227857
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
33795473
uniprot
proteins
pubmed
8647434
uniprot
proteins
pubmed
8758937
uniprot
proteins
pubmed
8942982
uniprot
proteins
pubmed
9045704
uniprot
proteins
sequence_length
800
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins