INSL3
entrez
3640
canonical
uniprot
P51460
canonical
ensembl
ENSG00000248099
resolver
ensp
ENSP00000321724
resolver
ensp
ENSP00000369017
resolver
genesymbol
INSL3
resolver
genesymbol_syn
RLF
resolver
genesymbol_syn
RLNL
resolver
hgnc
HGNC:6086
resolver
uniprot
B4DZ72
resolver
uniprot
G3XAG0
resolver
uniprot
Q3KPI5
resolver
uniprot
Q3KPI6
resolver
uniprot
Q6YNB5
resolver
uniprot
Q9UEA2
resolver
uniprot
Q9UPH6
resolver
uniprot_entry
INSL3_HUMAN
resolver
uniprot_sec
B4DZ72
resolver
uniprot_sec
G3XAG0
resolver
uniprot_sec
Q3KPI5
resolver
uniprot_sec
Q3KPI6
resolver
uniprot_sec
Q6YNB5
resolver
uniprot_sec
Q9UEA2
resolver
uniprot_sec
Q9UPH6
resolver
amino_acid_sequence
MDPRLPAWALVLLGPALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPATGGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGCTQQDLLTLCPY
uniprot
proteins
disease_involvement
DISEASE: Cryptorchidism (CRYPTO) [MIM:219050]: One of the most frequent congenital abnormalities in humans, involving 2-5% of male births. Cryptorchidism is associated with increased risk of infertility and testicular cancer. {ECO:0000269|PubMed:11095425, ECO:0000269|PubMed:11746019, ECO:0000269|PubMed:12601553}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
uniprot
proteins
mass_dalton
14502
uniprot
proteins
protein_family
Insulin family
uniprot
proteins
pubmed
10729310
uniprot
proteins
pubmed
10759163
uniprot
proteins
pubmed
11095425
uniprot
proteins
pubmed
11182749
uniprot
proteins
pubmed
11380919
uniprot
proteins
pubmed
11383919
uniprot
proteins
pubmed
11746019
uniprot
proteins
pubmed
12114498
uniprot
proteins
pubmed
12601553
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16867980
uniprot
proteins
pubmed
19086273
uniprot
proteins
pubmed
7852540
uniprot
proteins
pubmed
8020942
uniprot
proteins
pubmed
8034302
uniprot
proteins
sequence_length
131
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins