Spata33
entrez
320869
canonical
uniprot
Q8C624
canonical
ensembl
ENSMUSG00000048478
resolver
ensp
ENSMUSP00000058002
resolver
ensp
ENSMUSP00000148452
resolver
ensp
ENSMUSP00000148519
resolver
ensp
ENSMUSP00000286427
resolver
enst
ENSMUST00000060133
resolver
enst
ENSMUST00000212161
resolver
enst
ENSMUST00000212346
resolver
genesymbol
Spata33
resolver
uniprot
A0A1D5RLP4
resolver
uniprot
A0A1D5RLV5
resolver
uniprot_entry
A0A1D5RLP4_MOUSE
resolver
uniprot_entry
A0A1D5RLV5_MOUSE
resolver
uniprot_entry
SPT33_MOUSE
resolver
amino_acid_sequence
MGQSKSKPREKKEEEKSTTTLVTKSKEKVMEKEAKQSDKESQPAESLLFATSKHSRPSSSSEDKPETKQRSSKKRSVIPQIIITRASNETLISYGIPDNDEQRTIREHADWGPYHRHRSPSTIAAYDVHNTE
uniprot
proteins
function
FUNCTION: Plays an important role in sperm motility and male fertility (PubMed:34446558). Required for sperm midpiece flexibility and for the localization of sperm calcineurin to the mitochondria (PubMed:34446558). Promotes mitophagy as well as acts as an autophagy mediator in male germline cells (PubMed:33087875). Links damaged mitochondria to autophagosomes via its binding to the outer mitochondrial membrane protein VDAC2, as well as to key autophagy machinery component ATG16L1 (PubMed:33087875). {ECO:0000269|PubMed:33087875, ECO:0000269|PubMed:34446558}.
uniprot
proteins
mass_dalton
15038
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23844118
uniprot
proteins
pubmed
33087875
uniprot
proteins
pubmed
34446558
uniprot
proteins
sequence_length
132
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:23844118}. Nucleus {ECO:0000269|PubMed:23844118}. Cytoplasm {ECO:0000269|PubMed:33087875}. Mitochondrion {ECO:0000269|PubMed:33087875, ECO:0000269|PubMed:34446558}.
uniprot
proteins