Col25a1
entrez
77018
canonical
uniprot
Q99MQ5
canonical
ensembl
ENSMUSG00000058897
resolver
ensp
ENSMUSP00000079210
resolver
ensp
ENSMUSP00000101960
resolver
ensp
ENSMUSP00000158974
resolver
enst
ENSMUST00000080335
resolver
enst
ENSMUST00000106353
resolver
genesymbol
Col25a1
resolver
uniprot
B2RQR7
resolver
uniprot
E9Q5L6
resolver
uniprot
G3X9H6
resolver
uniprot_entry
B2RQR7_MOUSE
resolver
uniprot_entry
COPA1_MOUSE
resolver
uniprot_entry
E9Q5L6_MOUSE
resolver
uniprot_sec
G3X9H6
resolver
amino_acid_sequence
MLVKKLAGKGGGRESGSEDPRPLGQRCAGTMPSCTALATLLSVVAVAFCFYLGVKTNDLQARIAALESAKGTPSFHPLSDTVDELKAMVQEKVERLLAQKSYEHMAKIRTAREAPLECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGTPGMDGQKGEPGSPGAAGQSGLPGPKGEPGKEGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGDRGEAGPPGRGERGDPGAPGPKGKQGESGARGPKGSKGDRGDKGDSGALGPRGPPGQKGDPGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGVDGEQGLKGSKGDMGDPGVPGEKGGLGLPGLPGANGVKGEKGDTGLPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGASGLDGKPGSRGADGPIGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPGLDGLDAPCQLGPDGLPMPGCWQK
uniprot
proteins
function
FUNCTION: Inhibits fibrillization of amyloid-beta peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin (By similarity). {ECO:0000250|UniProtKB:Q9BXS0}.
uniprot
proteins
mass_dalton
65377
uniprot
proteins
post_translational_modification
PTM: Undergoes proteolytic cleavage by furin protease to yield the soluble collagen-like Alzheimer amyloid plaque component. {ECO:0000250|UniProtKB:Q9BXS0}.; PTM: Glycosylated. {ECO:0000250|UniProtKB:Q9BXS0}.; PTM: Hydroxylated on proline and lysine residues. {ECO:0000250|UniProtKB:Q9BXS0}.
uniprot
proteins
pubmed
11927537
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
666
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=After proteolytic cleavage, CLAC is secreted. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 34..54; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins