HAO2
entrez
51179
canonical
uniprot
Q9NYQ3
canonical
ensembl
ENSG00000116882
resolver
ensp
ENSP00000316339
resolver
ensp
ENSP00000354314
resolver
ensp
ENSP00000534590
resolver
ensp
ENSP00000534591
resolver
ensp
ENSP00000534593
resolver
ensp
ENSP00000762652
resolver
ensp
ENSP00000762653
resolver
ensp
ENSP00000788579
resolver
ensp
ENSP00000788580
resolver
genesymbol
HAO2
resolver
genesymbol_syn
HAOX2
resolver
hgnc
HGNC:4810
resolver
uniprot
Q2TU86
resolver
uniprot
Q5QP00
resolver
uniprot
Q9UJS6
resolver
uniprot_entry
HAOX2_HUMAN
resolver
uniprot_sec
Q2TU86
resolver
uniprot_sec
Q5QP00
resolver
uniprot_sec
Q9UJS6
resolver
amino_acid_sequence
MSLVCLTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRTTIQGEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAAPEGLRWFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQLRRNLTLTDLQSPKKGNAIPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDAELAVKHNVQGIIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRNLVQFSRL
uniprot
proteins
ec_number
1.1.3.15
uniprot
proteins
function
FUNCTION: Oxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, to the corresponding 2-oxoacids (PubMed:10777549). Its role in the oxidation of 2-hydroxy fatty acids may contribute to the general pathway of fatty acid alpha-oxidation (Probable). Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. Is not active on glycolate, glyoxylate, L-lactate and 2-hydroxybutanoate (PubMed:10777549). {ECO:0000269|PubMed:10777549, ECO:0000305|PubMed:10777549}.
uniprot
proteins
mass_dalton
38839
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid metabolism. {ECO:0000305|PubMed:10777549}.
uniprot
proteins
protein_family
FMN-dependent alpha-hydroxy acid dehydrogenase family
uniprot
proteins
pubmed
10777549
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
351
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000269|PubMed:10777549}.
uniprot
proteins