IMP3
entrez
55272
canonical
uniprot
Q9NV31
canonical
ensembl
ENSG00000177971
resolver
ensp
ENSP00000326981
resolver
ensp
ENSP00000385217
resolver
enst
ENST00000314852
resolver
enst
ENST00000403490
resolver
genesymbol
IMP3
resolver
genesymbol_syn
C15orf12
resolver
genesymbol_syn
MRPS4
resolver
hgnc
HGNC:14497
resolver
uniprot
B3KQ67
resolver
uniprot
Q53G10
resolver
uniprot_entry
IMP3_HUMAN
resolver
uniprot_sec
B3KQ67
resolver
uniprot_sec
Q53G10
resolver
amino_acid_sequence
MVRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREDYTRYNQLSRAVRELARRLRDLPERDQFRVRASAALLDKLYALGLVPTRGSLELCDFVTASSFCRRRLPTVLLKLRMAQHLQAAVAFVEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHVLEYNEERDDFDLEA
uniprot
proteins
function
FUNCTION: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). {ECO:0000269|PubMed:12655004, ECO:0000269|PubMed:34516797}.
uniprot
proteins
mass_dalton
21850
uniprot
proteins
protein_family
Universal ribosomal protein uS4 family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
12655004
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
34516797
uniprot
proteins
sequence_length
184
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:12655004, ECO:0000269|PubMed:34516797}.
uniprot
proteins