Gnl2
entrez
230737
canonical
uniprot
Q99LH1
canonical
ensembl
ENSMUSG00000028869
resolver
ensp
ENSMUSP00000030684
resolver
enst
ENSMUST00000030684
resolver
genesymbol
Gnl2
resolver
uniprot
B1ASC3
resolver
uniprot
Q3V3N5
resolver
uniprot
Q8BIF8
resolver
uniprot_entry
NOG2_MOUSE
resolver
uniprot_entry
Q3V3N5_MOUSE
resolver
uniprot_sec
B1ASC3
resolver
uniprot_sec
Q8BIF8
resolver
amino_acid_sequence
MVKPKYKGRSTINRSAASTNPDRVQGAGGQNMRDRGTIRRLNMYRQKERRNSRGKVIKPLQYQSTVASGTVARVEPNIKWFGNTRVIKQASLQKFQEEMDKVMKDPYKVVMKQSKLPMSLLHDRIQPHNAKVHILDTESFESTFGPKSQRKRPNLFASDMQSLLENAEMSTESYDQGKDRDLVMEDTGVRNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIEAYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKAPQDHIGAVLERAKPEYISKTYKIESWENAEDFLEKLALRTGKLLKGGEPDMLTVSKMVLNDWQRGRIPFFVKPPNAELPTDSQLPPSSPLEVPTETTQNNPEEETTETEVERSDSITEKEPEGDCSQDRNSEMQQILARVRQNFGKINVGPQFSADDLVPVEMSDLEDLESSGEEEEQEQEQPGEDAEEERSPDTQEEPVGNDTKAVLRALDEKIAKYQRFLNKAKAKKFSAVRISKDLSEKVFAKYKEEKKTSAEDSDAAPTKKARKWDAQMEEEPSNKTQRMLTCKERRRAARQQQSKKVGVRYYETHNVKNRNRNKKKTSDSEGQKHRRNKFRQKQ
uniprot
proteins
function
FUNCTION: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels. {ECO:0000250|UniProtKB:Q13823}.
uniprot
proteins
mass_dalton
83345
uniprot
proteins
protein_family
NOG2 subfamily
uniprot
proteins
protein_family
TRAFAC class YlqF/YawG GTPase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
728
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q13823}.
uniprot
proteins