Shld2
entrez
75698
canonical
uniprot
Q3UEN2
canonical
ensembl
ENSMUSG00000041471
resolver
ensp
ENSMUSP00000107548
resolver
ensp
ENSMUSP00000244790
resolver
ensp
ENSMUSP00000244791
resolver
ensp
ENSMUSP00000244792
resolver
ensp
ENSMUSP00000244798
resolver
ensp
ENSMUSP00000330601
resolver
enst
ENSMUST00000111917
resolver
genesymbol
Shld2
resolver
genesymbol_syn
Fam35a
resolver
genesymbol_syn
Rinn2
resolver
uniprot
E9Q8K3
resolver
uniprot_entry
SHLD2_MOUSE
resolver
uniprot_sec
E9Q8K3
resolver
amino_acid_sequence
MSQGSQVHIFLGAPVAPLKTTVSQGTASLMSTANAWEKVRLFYKQHSLYLKAGDQEFKNLEDCQVPKGLGPPGLLSGDVLTTSVRRSAQVDEDFKHSASEAQSVKSQVNLSDMTSGQMCGLGDGVQHLPEEEKDQKLQCKNKKITDEQSKNQSDPCVRNFQRDLFALDLKCAAKLDLGCCTEQMSTGTKPEPTGHRERQSQESFSDTRCEPQSEGAVRKASDQRLSAEAEFLSVLTSSQRAFLAQGNDKGQDCINKSTVNMEAEPTGSQGVRRTEGDFSKPGGDFEEESENEQSQVYSLELFSPVCPESESSHSHINPGKNLENTSSQELFSNEENLPPNELCSSHPSTANRSWSCKDDSHHSKALSEVHQVSKKPRMDSNIREAAKAVPQRVMSELKDSKKISLIKNCDSKNQKYNCLVMVLTPCHVKEITIKSGPNSGSKVPLATIVVIDQSEIKKRVVLWRTAAFGALTVFLGDIILLTDVVLYEDQWIGETVLQSTFTSQLLNLGSYSYVQPEKYSNVIANVILQDLLTYVSTKHSYLKDLPQRQPQKMNTVEFVELEQLQPDILVHAVLRVVDVTVLTEALYSYRGQKQRKVVLTVEQAQGQHYVLVLWGPGAAWYTQLQRKKDSIWEFKYLFVQRNSILENLELHTTLWSSCECLFDDDTRAISFKTKFQKNTSSFVKISDLATHLEDKYSGVVLIKAKVSELVFSAAAAQKIALNARSTLQSIFSSLPSIVYAGCAHCGSELETDENRIYRQCLSCLPFVGKKIFYRPALMTIVDGRYNTCVHVGSKMMEQILLNISPDCLNRVIVPSSEVTYGMVASDLLHSLLAVSAEPCVLKIQSLFELDENSYPLQQDFSLLDFCPDSRKLWSPGLSLRAEGTGGIPGKE
uniprot
proteins
function
FUNCTION: Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. {ECO:0000250|UniProtKB:Q86V20}.
uniprot
proteins
mass_dalton
99090
uniprot
proteins
protein_family
SHLD2 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
891
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Chromosome {ECO:0000250|UniProtKB:Q86V20}.
uniprot
proteins