Aebp1
entrez
305494
canonical
uniprot
A2RUV9
canonical
ensembl
ENSRNOG00000013720
resolver
ensembl
ENSRNOG00055029591
resolver
ensembl
ENSRNOG00060031827
resolver
ensembl
ENSRNOG00065020330
resolver
ensp
ENSRNOP00000018846
resolver
ensp
ENSRNOP00055042226
resolver
ensp
ENSRNOP00060045599
resolver
ensp
ENSRNOP00065027494
resolver
enst
ENSRNOT00000018846
resolver
enst
ENSRNOT00055051257
resolver
enst
ENSRNOT00060055154
resolver
enst
ENSRNOT00065034335
resolver
genesymbol
Aebp1
resolver
genesymbol_syn
Aclp
resolver
uniprot
A0A0H2UHL3
resolver
uniprot_entry
A0A0H2UHL3_RAT
resolver
uniprot_entry
AEBP1_RAT
resolver
amino_acid_sequence
MAAVRTASLLCGLLALLALCPEGSPQTVLTDDEIQEFLEGFLSEFETQSPPREDDVEAQPLPEPTQRARKSKAGGKPRADAEAPPEKNKDKEKKGKKDKGPKAAKHLEGSTRPTKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKRPSAGKRFSTVAPLETPERSLTSPSNPGTRELPEERGRTSLNTWQGQGEETQVEARQHRPEPEEETEMPTLDYNDQIEREDYEDFEYIRRQKQPRPTPSRKRIWPEPPEEKTQEPEERKEVDPPLKPLLPPDYGDGYLIPNYDDLDYYFPHPPPQKPDVGQEVDEEKEELKKPKKEGSSPKEDTEDKWAAEKNKDHKAGPRKGEELEEEWGPVEKIKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQAGANEDDYYDGAWCAEDESQTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCPVTPVYSYYAQNEVVTTDSLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAGMHGNEVLGRELLLLLMQYLCHEYRDGNPRVRNLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWAAEEKKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIISWMEKNPFVLGANLNGGERLVSYPYDMARTPSQEQLLAAALAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTMTEPYRGGCQAQDYTSGMGIVNGAKWNPRSGTFNDFSYLHTNCLELSIYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTSSAKICNVDYDIGATQCNFILARSNWKRIREILAMNGNRPILRVDPSRPMTPQQRRLQQRRLRYRLRMREQMRLRRLNSTTGPATSPTPALTLPPSPTPGSTSRLWEILPTTAAGWEESETETYTEVVTEFETEYGPDLEVEELEEEEEEEEEMDTGLTFPVTTVETYTVNFGDF
uniprot
proteins
function
FUNCTION: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix (By similarity). May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. {ECO:0000250|UniProtKB:Q640N1, ECO:0000250|UniProtKB:Q8IUX7}.
uniprot
proteins
mass_dalton
128061
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by MAPK1 in vitro. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase M14 family
uniprot
proteins
pubmed
11738825
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9624159
uniprot
proteins
sequence_length
1128
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q640N1}.
uniprot
proteins