HSPBP1
entrez
23640
canonical
uniprot
Q9NZL4
canonical
ensembl
ENSG00000133265
resolver
ensp
ENSP00000255631
resolver
ensp
ENSP00000398244
resolver
ensp
ENSP00000467574
resolver
ensp
ENSP00000544571
resolver
ensp
ENSP00000603793
resolver
ensp
ENSP00000646880
resolver
ensp
ENSP00000646881
resolver
ensp
ENSP00000721433
resolver
ensp
ENSP00000721435
resolver
genesymbol
HSPBP1
resolver
genesymbol_syn
HSPBP
resolver
hgnc
HGNC:24989
resolver
uniprot
B3KQP0
resolver
uniprot
B4DG11
resolver
uniprot
O95351
resolver
uniprot
Q6ZNU5
resolver
uniprot_entry
HPBP1_HUMAN
resolver
uniprot_sec
B3KQP0
resolver
uniprot_sec
B4DG11
resolver
uniprot_sec
O95351
resolver
uniprot_sec
Q6ZNU5
resolver
amino_acid_sequence
MSDEGSRGSRLPLALPPASQGCSSGGGGGGSSAGGSGNSRPPRNLQGLLQMAITAGSEEPDPPPEPMSEERRQWLQEAMSAAFRGQREEVEQMKSCLRVLSQPMPPTAGEAEQAADQQEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVRTEHSPFHEHVLGALCSLVTDFPQGVRECREPELGLEELLRHRCQLLQQHEEYQEELEFCEKLLQTCFSSPADDSMDR
uniprot
proteins
function
FUNCTION: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. {ECO:0000269|PubMed:10786638, ECO:0000269|PubMed:12651857, ECO:0000269|PubMed:15215316, ECO:0000269|PubMed:21247889, ECO:0000269|PubMed:9830037}.
uniprot
proteins
mass_dalton
39303
uniprot
proteins
pubmed
10786638
uniprot
proteins
pubmed
12651857
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15215316
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15498874
uniprot
proteins
pubmed
15694338
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21247889
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
9830037
uniprot
proteins
sequence_length
359
uniprot
proteins