TMEM88
entrez
92162
canonical
uniprot
Q6PEY1
canonical
ensembl
ENSG00000167874
resolver
ensp
ENSP00000301599
resolver
ensp
ENSP00000459725
resolver
ensp
ENSP00000526602
resolver
enst
ENST00000301599
resolver
enst
ENST00000574668
resolver
genesymbol
TMEM88
resolver
genesymbol_syn
TMEM88A
resolver
hgnc
HGNC:32371
resolver
uniprot
I3L2J3
resolver
uniprot_entry
I3L2J3_HUMAN
resolver
uniprot_entry
TMM88_HUMAN
resolver
amino_acid_sequence
MADVPGAQRAVPGDGPEPRDPLDCWACAVLVTAQNLLVAAFNLLLLVLVLGTILLPAVTMLGFGFLCHSQFLRSQAPPCTAHLRDPGFTALLVTGFLLLVPLLVLALASYRRLCLRLRLADCLVPYSRALYRRRRAPQPRQIRASPGSQAVPTSGKVWV
uniprot
proteins
function
FUNCTION: Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development. {ECO:0000269|PubMed:23924634}.
uniprot
proteins
mass_dalton
17251
uniprot
proteins
protein_family
TMEM88 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21044957
uniprot
proteins
pubmed
23924634
uniprot
proteins
sequence_length
159
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:21044957}; Multi-pass membrane protein {ECO:0000269|PubMed:21044957}.
uniprot
proteins
transmembrane_region
TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins