CHST15
entrez
51363
canonical
uniprot
Q7LFX5
canonical
ensembl
ENSG00000182022
resolver
ensp
ENSP00000333947
resolver
ensp
ENSP00000402394
resolver
ensp
ENSP00000485905
resolver
ensp
ENSP00000544608
resolver
ensp
ENSP00000544611
resolver
ensp
ENSP00000587932
resolver
ensp
ENSP00000626409
resolver
ensp
ENSP00000626410
resolver
ensp
ENSP00000783908
resolver
ensp
ENSP00000783910
resolver
genesymbol
CHST15
resolver
genesymbol_syn
BRAG
resolver
genesymbol_syn
GALNAC4S6ST
resolver
genesymbol_syn
KIAA0598
resolver
hgnc
HGNC:18137
resolver
uniprot
B4DH74
resolver
uniprot
O60338
resolver
uniprot
O60474
resolver
uniprot
Q86VM4
resolver
uniprot_entry
B4DH74_HUMAN
resolver
uniprot_entry
CHSTF_HUMAN
resolver
uniprot_sec
O60338
resolver
uniprot_sec
O60474
resolver
uniprot_sec
Q86VM4
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by phenyl beta-GalNAc(4,6-SO(4)). {ECO:0000269|PubMed:16024005}.
uniprot
proteins
amino_acid_sequence
MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNPSLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQELHMFSVIPNKFLPNSKSPCWYEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHLAHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFYRPFNARLAQVLADEAFAWKTT
uniprot
proteins
ec_number
2.8.2.33
uniprot
proteins
function
FUNCTION: Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo. {ECO:0000269|PubMed:11572857, ECO:0000269|PubMed:12874280}.
uniprot
proteins
mass_dalton
64926
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000269|PubMed:10749872}.
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
10749872
uniprot
proteins
pubmed
11032940
uniprot
proteins
pubmed
11572857
uniprot
proteins
pubmed
12874280
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16024005
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
9628581
uniprot
proteins
pubmed
9754571
uniprot
proteins
sequence_length
561
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305|PubMed:10749872}; Single-pass type II membrane protein {ECO:0000305|PubMed:10749872}. Note=A small fraction may also be present at the cell surface, where it acts as a B-cell receptor.
uniprot
proteins
transmembrane_region
TRANSMEM 81..101; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins