Mok
entrez
26448
canonical
uniprot
Q9WVS4
canonical
ensembl
ENSMUSG00000056458
resolver
ensp
ENSMUSP00000068904
resolver
ensp
ENSMUSP00000082041
resolver
ensp
ENSMUSP00000242440
resolver
ensp
ENSMUSP00000242447
resolver
ensp
ENSMUSP00000242449
resolver
ensp
ENSMUSP00000242450
resolver
ensp
ENSMUSP00000242454
resolver
ensp
ENSMUSP00000242455
resolver
ensp
ENSMUSP00000242462
resolver
ensp
ENSMUSP00000334247
resolver
ensp
ENSMUSP00000334251
resolver
ensp
ENSMUSP00000334252
resolver
enst
ENSMUST00000084974
resolver
genesymbol
Mok
resolver
genesymbol_syn
Rage
resolver
genesymbol_syn
Stk30
resolver
uniprot
F6YJM8
resolver
uniprot
Q5M8P5
resolver
uniprot
Q8CFU4
resolver
uniprot_entry
F6YJM8_MOUSE
resolver
uniprot_entry
MOK_MOUSE
resolver
uniprot_entry
Q5M8P5_MOUSE
resolver
uniprot_sec
Q8CFU4
resolver
activity_regulation
ACTIVITY REGULATION: Phosphorylation appears to increase the enzymatic activity.
uniprot
proteins
amino_acid_sequence
MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNSLREIQALRRLNPHPNILALHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIMLYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTANLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQVQRAAETQTLAKHRRAFCPKFSMVPESSSHNWSFSQEGRKQKQSLRHEEGHARRQGPTSLMELPKLRLSGMTKLSSCSSPALRSVLGTGANGKVPVLRPLKCAAVNKKTDTQKDIKPHLKHYHLPTINRKGGEY
uniprot
proteins
ec_number
2.7.11.22
uniprot
proteins
function
FUNCTION: Able to phosphorylate several exogenous substrates and to undergo autophosphorylation (PubMed:10421840). Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner (PubMed:25243405). {ECO:0000269|PubMed:10421840, ECO:0000269|PubMed:25243405}.
uniprot
proteins
mass_dalton
48065
uniprot
proteins
mutagenesis
MUTAGEN 159; /note="T->A: Loss of activity; when associated with F-161."; /evidence="ECO:0000269|PubMed:10421840"; MUTAGEN 161; /note="Y->F: Loss of activity; when associated with A-159."; /evidence="ECO:0000269|PubMed:10421840
uniprot
proteins
post_translational_modification
PTM: Autophosphorylated.
uniprot
proteins
protein_family
CDC2/CDKX subfamily
uniprot
proteins
protein_family
CMGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
10421840
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
25243405
uniprot
proteins
sequence_length
420
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10421840}. Cell projection, cilium {ECO:0000269|PubMed:25243405}. Nucleus {ECO:0000269|PubMed:25243405}.
uniprot
proteins