FTMT
entrez
94033
canonical
uniprot
Q8N4E7
canonical
ensembl
ENSG00000181867
resolver
ensp
ENSP00000313691
resolver
enst
ENST00000321339
resolver
genesymbol
FTMT
resolver
hgnc
HGNC:17345
resolver
uniprot_entry
FTMT_HUMAN
resolver
amino_acid_sequence
MLSCFRLLSRHISPSLASLRPVRCCFALPLRWAPGRPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMGAPDAGLAEYLFDTHTLGNENKQN
uniprot
proteins
ec_number
1.16.3.1
uniprot
proteins
function
FUNCTION: Catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form (PubMed:11323407, PubMed:15201052). Important for iron homeostasis (PubMed:11323407, PubMed:15201052). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:11323407, PubMed:15201052). {ECO:0000269|PubMed:11323407, ECO:0000269|PubMed:15201052}.
uniprot
proteins
mass_dalton
27538
uniprot
proteins
mutagenesis
MUTAGEN 204; /note="S->A: Increases ferroxidase activity and iron binding."; /evidence="ECO:0000269|PubMed:15201052
uniprot
proteins
protein_family
Ferritin family
uniprot
proteins
pubmed
11323407
uniprot
proteins
pubmed
15201052
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
242
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11323407}.
uniprot
proteins