RNF181
entrez
51255
canonical
uniprot
Q9P0P0
canonical
ensembl
ENSG00000168894
resolver
ensp
ENSP00000306906
resolver
ensp
ENSP00000415246
resolver
enst
ENST00000306368
resolver
genesymbol
RNF181
resolver
hgnc
HGNC:28037
resolver
uniprot
Q53H81
resolver
uniprot_entry
RN181_HUMAN
resolver
uniprot_sec
Q53H81
resolver
amino_acid_sequence
MASYFDEHDCEPSDPEQETRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTVVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNSCPLCRYELPTDDDTYEEHRRDKARKQQQQHRLENLHGAMYT
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:18331836). Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1 (PubMed:24811749). {ECO:0000269|PubMed:18331836, ECO:0000269|PubMed:24811749}.
uniprot
proteins
mass_dalton
17909
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:18331836, ECO:0000269|PubMed:24811749}.
uniprot
proteins
post_translational_modification
PTM: Autoubiquitinated as part of the enzymatic reaction. {ECO:0000269|PubMed:18331836}.
uniprot
proteins
protein_family
RNF181 family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
18331836
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24811749
uniprot
proteins
sequence_length
153
uniprot
proteins