SLC9C1
entrez
285335
canonical
uniprot
Q4G0N8
canonical
ensembl
ENSG00000172139
resolver
ensembl
ENSG00000285044
resolver
ensp
ENSP00000306627
resolver
ensp
ENSP00000420688
resolver
genesymbol
SLC9C1
resolver
genesymbol_syn
SLC9A10
resolver
hgnc
HGNC:31401
resolver
uniprot
Q6ZRP4
resolver
uniprot
Q7RTP2
resolver
uniprot_entry
SL9C1_HUMAN
resolver
uniprot_sec
Q6ZRP4
resolver
uniprot_sec
Q7RTP2
resolver
amino_acid_sequence
MAGIFKEFFFSTEDLPEVILTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTVFGDDVNHISLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEETLLLEFWTFLSRIAFLMVFTFFGLLIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSRVGHEFSWRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITLVVNRFILPVAVTILGLRDATSTKYKSVCCTFQHFQELTKSAASALKFDKDLANADWNMIEKAITLENPYMLNEEETTEHQKVKCPHCNKEIDEIFNTEAMELANRRLLSAQIASYQRQYRNEILSQSAVQVLVGAAESFGEKKGKCMSLDTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGPSKYFFFRICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKLIAPKLLQIIDKRMSHQKTFWYGILKGYVQGEADIMTIIDQITSSKQIKQMLLKQVIRNMEHAIKELGYLEYDHPEIAVTVKTKEEINVMLNMATEILKAFGLKGIISKTEGAGINKLIMAKKKEVLDSQSIIRPLTVEEVLYHIPWLDKNKDYINFIQEKAKVVTFDCGNDIFEEGDEPKGIYIIISGMVKLEKSKPGLGIDQMVESKEKDFPIIDTDYMLSGEIIGEINCLTNEPMKYSATCKTVVETCFIPKTHLYDAFEQCSPLIKQKMWLKLGLAITARKIREHLSYEDWNYNMQLKLSNIYVVDIPMSTKTDIYDENLIYVILIHGAVEDCLLRKTYRAPFLIPITCHQIQSIEDFTKVVIIQTPINMKTFRRNIRKFVPKHKSYLTPGLIGSVGTLEEGIQEERNVKEDGAHSAATARSPQPCSLLGTKFNCKESPRINLRKVRKE
uniprot
proteins
function
FUNCTION: Sperm-specific solute carrier involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (ADCY10). {ECO:0000250|UniProtKB:Q6UJY2}.
uniprot
proteins
mass_dalton
135206
uniprot
proteins
protein_family
Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family
uniprot
proteins
pubmed
12783626
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
37669933
uniprot
proteins
sequence_length
1177
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum membrane {ECO:0000250|UniProtKB:Q6UJY2}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..37; /note="Helical; Name=TM1"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 43..60; /note="Helical; Name=TM2"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 77..93; /note="Helical; Name=TM3"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 104..129; /note="Helical; Name=TM4"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 136..161; /note="Helical; Name=TM5"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 165..190; /note="Helical; Name=TM6"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 205..236; /note="Helical; Name=TM7, linker"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 241..262; /note="Helical; Name=TM8"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 266..279; /note="Helical; Name=TM9"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 287..319; /note="Helical; Name=TM10"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 325..354; /note="Helical; Name=TM11"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 361..391; /note="Helical; Name=TM12"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 396..426; /note="Helical; Name=TM13"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 613..633; /note="Helical; Name=S1"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 638..664; /note="Helical; Name=S2"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 672..696; /note="Helical; Name=S3"; /evidence="ECO:0000250|UniProtKB:A3RL54"; TRANSMEM 705..731; /note="Helical; Name=S4"; /evidence="ECO:0000250|UniProtKB:A3RL54
uniprot
proteins