Gpr107
entrez
277463
canonical
uniprot
Q8BUV8
canonical
ensembl
ENSMUSG00000000194
resolver
ensp
ENSMUSP00000056739
resolver
enst
ENSMUST00000056433
resolver
genesymbol
Gpr107
resolver
genesymbol_syn
AI790205
resolver
genesymbol_syn
Kiaa1624
resolver
uniprot
Q148Z6
resolver
uniprot
Q6ZPL4
resolver
uniprot
Q8BM58
resolver
uniprot
Q8BMN6
resolver
uniprot
Q8BTW1
resolver
uniprot_entry
GP107_MOUSE
resolver
uniprot_entry
Q148Z6_MOUSE
resolver
uniprot_sec
Q6ZPL4
resolver
uniprot_sec
Q8BM58
resolver
uniprot_sec
Q8BMN6
resolver
uniprot_sec
Q8BTW1
resolver
amino_acid_sequence
MAVPVPLGRFGSFCLRLLRLLALLELLVHPVLGRVHHLALKDDVRHKVHLNTFGFFKDGYMVVNVSSLSVNEPEGATDKDAEIGFSLDRTKNDGFSSYLDEDVNYCILKKKSMSSVTLVILDISGSIVKVRSPPEAGKQLPEIVFSKDEKILSQSQEPAVSSNPKDSEARRTLDGFKAGRSTVDSKAITERSFSIHKNDGVVSFQFFFNISTDDQEGLYSLYFHKCSGNNVKPGEQASFSLNIAITEKNPNSYLSAGEIPLPKLYVSMALFFFLSGTIWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKDSLFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLRLFRHYYVLIVCYIYFTRIIAFLLKFAVPFQWKWLYQLLDETATLVFFVLTGYKFRPASDNPYLQLSQEDDDLEMESVVTTSGVMENMKKVKKVSNGAVEPQGSWEGTA
uniprot
proteins
function
FUNCTION: Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor (By similarity). Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity). {ECO:0000250|UniProtKB:D3ZWZ9}.
uniprot
proteins
mass_dalton
62056
uniprot
proteins
post_translational_modification
PTM: Cleaved by FURIN to yield two fragments that remain associated via a disulfide bond. {ECO:0000250|UniProtKB:Q5VW38}.
uniprot
proteins
protein_family
LU7TM family
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26561648
uniprot
proteins
sequence_length
551
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:26561648}; Multi-pass membrane protein {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q5VW38}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 263..283; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 293..313; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 337..357; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 368..388; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 402..422; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 450..470; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 476..495; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins