SIGLEC14
entrez
100049587
canonical
uniprot
Q08ET2
canonical
ensembl
ENSG00000254415
resolver
ensp
ENSP00000354090
resolver
enst
ENST00000360844
resolver
genesymbol
SIGLEC14
resolver
hgnc
HGNC:32926
resolver
uniprot
Q6UXG0
resolver
uniprot_entry
SIG14_HUMAN
resolver
uniprot_sec
Q6UXG0
resolver
amino_acid_sequence
MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQRSSSSCICVTEKQQGSWPLVLTLIRGALMGAGFLLTYGLTWIYYTRCGGPQQSRAERPG
uniprot
proteins
function
FUNCTION: Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors. {ECO:0000269|PubMed:17012248}.
uniprot
proteins
mass_dalton
43970
uniprot
proteins
mutagenesis
MUTAGEN 362; /note="R->A: Loss of interaction with TYROBP."; /evidence="ECO:0000269|PubMed:17012248
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
protein_family
SIGLEC (sialic acid binding Ig-like lectin) family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
17012248
uniprot
proteins
sequence_length
396
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17012248}; Single-pass type I membrane protein {ECO:0000269|PubMed:17012248}.
uniprot
proteins
transmembrane_region
TRANSMEM 359..381; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins