NRF1
entrez
4899
canonical
uniprot
Q16656
canonical
ensembl
ENSG00000106459
resolver
ensp
ENSP00000309826
resolver
ensp
ENSP00000376922
resolver
ensp
ENSP00000376924
resolver
genesymbol
NRF1
resolver
hgnc
HGNC:7996
resolver
uniprot
A8K4C6
resolver
uniprot
B4DDV6
resolver
uniprot
Q15305
resolver
uniprot
Q96AN2
resolver
uniprot_entry
NRF1_HUMAN
resolver
uniprot_sec
A8K4C6
resolver
uniprot_sec
B4DDV6
resolver
uniprot_sec
Q15305
resolver
uniprot_sec
Q96AN2
resolver
amino_acid_sequence
MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQEVNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHLVPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNWATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAEATLQGGGQIVLSGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPVTTRISDSAVTMDGQAVEVVTLEQ
uniprot
proteins
function
FUNCTION: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
uniprot
proteins
mass_dalton
53541
uniprot
proteins
post_translational_modification
PTM: Phosphorylation enhances DNA binding. {ECO:0000269|PubMed:9228045}.
uniprot
proteins
protein_family
NRF1/Ewg family
uniprot
proteins
pubmed
11340167
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16908542
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
7629110
uniprot
proteins
pubmed
8034649
uniprot
proteins
pubmed
8253388
uniprot
proteins
pubmed
8541844
uniprot
proteins
pubmed
9228045
uniprot
proteins
sequence_length
503
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins