FABP2
entrez
2169
canonical
uniprot
P12104
canonical
ensembl
ENSG00000145384
resolver
ensp
ENSP00000274024
resolver
enst
ENST00000274024
resolver
genesymbol
FABP2
resolver
genesymbol_syn
FABPI
resolver
hgnc
HGNC:3556
resolver
uniprot
Q2NKJ1
resolver
uniprot_entry
FABPI_HUMAN
resolver
uniprot_sec
Q2NKJ1
resolver
amino_acid_sequence
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSTFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD
uniprot
proteins
function
FUNCTION: FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
uniprot
proteins
mass_dalton
15237
uniprot
proteins
mutagenesis
MUTAGEN 39; /note="L->G: Reduced stability."; /evidence="ECO:0000269|PubMed:14567680"; MUTAGEN 64; /note="E->G: Localized reduction in stability."; /evidence="ECO:0000269|PubMed:14567680"; MUTAGEN 65; /note="L->A: Reduced stability."; /evidence="ECO:0000269|PubMed:14567680"; MUTAGEN 65; /note="L->G: Reduced stability."; /evidence="ECO:0000269|PubMed:14567680"; MUTAGEN 67; /note="V->G: Localized reduction in stability."; /evidence="ECO:0000269|PubMed:14567680"; MUTAGEN 90; /note="L->G: Reduced stability."; /evidence="ECO:0000269|PubMed:14567680"; MUTAGEN 123; /note="V->G: Reduced stability."; /evidence="ECO:0000269|PubMed:14567680
uniprot
proteins
protein_family
Calycin superfamily
uniprot
proteins
protein_family
Fatty-acid binding protein (FABP) family
uniprot
proteins
pubmed
10070036
uniprot
proteins
pubmed
12809489
uniprot
proteins
pubmed
12899384
uniprot
proteins
pubmed
14563446
uniprot
proteins
pubmed
14567680
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
2824476
uniprot
proteins
pubmed
7883976
uniprot
proteins
pubmed
9204553
uniprot
proteins
sequence_length
132
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins