PATZ1
entrez
23598
canonical
uniprot
Q9HBE1
canonical
ensembl
ENSG00000100105
resolver
ensp
ENSP00000215919
resolver
ensp
ENSP00000266269
resolver
ensp
ENSP00000337520
resolver
ensp
ENSP00000384173
resolver
genesymbol
PATZ1
resolver
genesymbol_syn
PATZ
resolver
genesymbol_syn
RIAZ
resolver
genesymbol_syn
ZBTB19
resolver
genesymbol_syn
ZNF278
resolver
genesymbol_syn
ZSG
resolver
hgnc
HGNC:13071
resolver
uniprot
Q9HBE2
resolver
uniprot
Q9HBE3
resolver
uniprot
Q9P1A9
resolver
uniprot
Q9UDU0
resolver
uniprot
Q9Y529
resolver
uniprot_entry
PATZ1_HUMAN
resolver
uniprot_sec
Q9HBE2
resolver
uniprot_sec
Q9HBE3
resolver
uniprot_sec
Q9P1A9
resolver
uniprot_sec
Q9UDU0
resolver
uniprot_sec
Q9Y529
resolver
amino_acid_sequence
MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK
uniprot
proteins
disease_involvement
DISEASE: Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1. {ECO:0000269|PubMed:10949935}.
uniprot
proteins
function
FUNCTION: Transcriptional regulator that plays a role in many biological processes such as embryogenesis, senescence, T-cell development or neurogenesis (PubMed:10713105, PubMed:25755280, PubMed:31875552). Interacts with the TP53 protein to control genes that are important in proliferation and in the DNA-damage response. Mechanistically, the interaction inhibits the DNA binding and transcriptional activity of TP53/p53 (PubMed:25755280). Part of the transcriptional network modulating regulatory T-cell development and controls the generation of the regulatory T-cell pool under homeostatic conditions (PubMed:31875552). {ECO:0000269|PubMed:10713105, ECO:0000269|PubMed:25755280, ECO:0000269|PubMed:31875552}.; FUNCTION: (Microbial infection) Plays a positive role in viral cDNA synthesis. {ECO:0000269|PubMed:31060775}.
uniprot
proteins
mass_dalton
74060
uniprot
proteins
protein_family
Krueppel C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
10713105
uniprot
proteins
pubmed
10949935
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25755280
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
31060775
uniprot
proteins
pubmed
31875552
uniprot
proteins
sequence_length
687
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10713105}.
uniprot
proteins