Q9WUS4
uniprot
Q9WUS4
canonical
amino_acid_sequence
MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLGVAAEDVWDDEQSAFACNTQQPGCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRDFEKQRQKKKLYLRAQMENPELDLEEQQRVDKELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMHPIYKCTQAPCPNSVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRALDGKSSSGNTENETGPPFHSTNYSGTQQCMICSSLPERISLLQANNKQQVIRVNIPRSKSMWQIPHPRQLEVDVSCGKRDWAEKIESCAQLHVHSPCPHDRSARIQHPGQQPCHSVFGPKNAMSQSWFGTMTASQHRPSSALETWERSQGPEASGRSLTDRQSHFQGSDGSARESGVWTDRLGPGSRKASFLSRLMSEKGQRHSDSGSSRSLNSSCLDFSHGENSPSPLPSATGHRASMVSKSSHVDSPPHSSFIIHETYVYVY
uniprot
proteins
function
FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning. {ECO:0000269|PubMed:15147297, ECO:0000269|PubMed:16820008, ECO:0000269|PubMed:17681699, ECO:0000269|PubMed:18320035}.
uniprot
proteins
mass_dalton
57127
uniprot
proteins
protein_family
Alpha-type (group II) subfamily
uniprot
proteins
protein_family
Connexin family
uniprot
proteins
pubmed
10329667
uniprot
proteins
pubmed
12881038
uniprot
proteins
pubmed
15147297
uniprot
proteins
pubmed
16820008
uniprot
proteins
pubmed
17681699
uniprot
proteins
pubmed
18320035
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
505
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17681699}; Multi-pass membrane protein {ECO:0000269|PubMed:17681699}. Cell junction, gap junction {ECO:0000269|PubMed:17681699}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..37; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 166..186; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 210..230; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins