Myl12b
entrez
67938
canonical
uniprot
Q3THE2
canonical
ensembl
ENSMUSG00000034868
resolver
ensembl
ENSMUSG00000117098
resolver
ensp
ENSMUSP00000042364
resolver
ensp
ENSMUSP00000156763
resolver
ensp
ENSMUSP00000156883
resolver
enst
ENSMUST00000038446
resolver
enst
ENSMUST00000233004
resolver
enst
ENSMUST00000233357
resolver
genesymbol
Myl12b
resolver
genesymbol_syn
Mrlc2
resolver
genesymbol_syn
Mylc2b
resolver
uniprot
Q3TVH2
resolver
uniprot
Q9CQL8
resolver
uniprot_entry
ML12B_MOUSE
resolver
uniprot_sec
Q3TVH2
resolver
uniprot_sec
Q9CQL8
resolver
amino_acid_sequence
MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
uniprot
proteins
function
FUNCTION: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion. {ECO:0000250|UniProtKB:O14950}.
uniprot
proteins
mass_dalton
19779
uniprot
proteins
post_translational_modification
PTM: Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge. Phosphorylation is reduced following epigallocatechin-3-O-gallate treatment. {ECO:0000250|UniProtKB:O14950}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24825904
uniprot
proteins
sequence_length
172
uniprot
proteins