TENT2
entrez
167153
canonical
uniprot
Q6PIY7
canonical
ensembl
ENSG00000164329
resolver
ensp
ENSP00000296783
resolver
ensp
ENSP00000393412
resolver
ensp
ENSP00000397563
resolver
ensp
ENSP00000421966
resolver
ensp
ENSP00000556057
resolver
ensp
ENSP00000556058
resolver
ensp
ENSP00000556059
resolver
ensp
ENSP00000556060
resolver
ensp
ENSP00000556061
resolver
ensp
ENSP00000556064
resolver
ensp
ENSP00000556065
resolver
ensp
ENSP00000556066
resolver
ensp
ENSP00000556067
resolver
ensp
ENSP00000556068
resolver
ensp
ENSP00000556069
resolver
ensp
ENSP00000556070
resolver
ensp
ENSP00000556071
resolver
ensp
ENSP00000556074
resolver
ensp
ENSP00000556077
resolver
ensp
ENSP00000556078
resolver
ensp
ENSP00000556079
resolver
ensp
ENSP00000593637
resolver
ensp
ENSP00000593639
resolver
ensp
ENSP00000617555
resolver
ensp
ENSP00000617557
resolver
ensp
ENSP00000617563
resolver
ensp
ENSP00000617566
resolver
ensp
ENSP00000617567
resolver
ensp
ENSP00000643805
resolver
ensp
ENSP00000700152
resolver
enst
ENST00000504233
resolver
enst
ENST00000886020
resolver
genesymbol
TENT2
resolver
genesymbol_syn
GLD2
resolver
genesymbol_syn
PAPD4
resolver
hgnc
HGNC:26776
resolver
uniprot
D6RAF2
resolver
uniprot
Q86WZ2
resolver
uniprot
Q8N927
resolver
uniprot_entry
D6RAF2_HUMAN
resolver
uniprot_entry
GLD2_HUMAN
resolver
uniprot_sec
Q86WZ2
resolver
uniprot_sec
Q8N927
resolver
amino_acid_sequence
MFPNSILGRPPFTPNHQQHNNFFTLSPTVYSHQQLIDAQFNFQNADLSRAVSLQQLTYGNVSPIQTSASPLFRGRKRLSDEKNLPLDGKRQRFHSPHQEPTVVNQIVPLSGERRYSMPPLFHTHYVPDIVRCVPPFREIAFLEPREITLPEAKDKLSQQILELFETCQQQISDLKKKELCRTQLQREIQLLFPQSRLFLVGSSLNGFGTRSSDGDLCLVVKEEPCFFQVNQKTEARHILTLVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHQINDASRGTLSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSPAIQLHLVHQAPCNVPPYLSKNESNLGDLLLGFLKYYATEFDWNSQMISVREAKAIPRPDGIEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWHRLKNKRDLNSILPVRAAVLKR
uniprot
proteins
ec_number
2.7.7.19
uniprot
proteins
function
FUNCTION: Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail (PubMed:15070731, PubMed:31792053). In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs (PubMed:15070731). Does not play a role in replication-dependent histone mRNA degradation (PubMed:18172165). Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs (PubMed:23200856, PubMed:31792053). {ECO:0000269|PubMed:15070731, ECO:0000269|PubMed:18172165, ECO:0000269|PubMed:23200856, ECO:0000269|PubMed:31792053}.
uniprot
proteins
mass_dalton
56028
uniprot
proteins
mutagenesis
MUTAGEN 215; /note="D->A: Catalytically inactive."; /evidence="ECO:0000269|PubMed:23200856
uniprot
proteins
protein_family
DNA polymerase type-B-like family
uniprot
proteins
protein_family
GLD2 subfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15070731
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15987818
uniprot
proteins
pubmed
18172165
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23200856
uniprot
proteins
pubmed
31792053
uniprot
proteins
sequence_length
484
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q91YI6}. Nucleus {ECO:0000250|UniProtKB:Q91YI6}.
uniprot
proteins