EGFL7
entrez
51162
canonical
uniprot
Q9UHF1
canonical
ensembl
ENSG00000172889
resolver
ensp
ENSP00000307843
resolver
ensp
ENSP00000360763
resolver
ensp
ENSP00000360764
resolver
ensp
ENSP00000385639
resolver
ensp
ENSP00000563692
resolver
ensp
ENSP00000563693
resolver
ensp
ENSP00000563694
resolver
ensp
ENSP00000563695
resolver
ensp
ENSP00000563696
resolver
ensp
ENSP00000563697
resolver
ensp
ENSP00000563698
resolver
ensp
ENSP00000563699
resolver
ensp
ENSP00000563700
resolver
ensp
ENSP00000563701
resolver
ensp
ENSP00000563702
resolver
ensp
ENSP00000563703
resolver
ensp
ENSP00000563704
resolver
ensp
ENSP00000563705
resolver
ensp
ENSP00000563706
resolver
ensp
ENSP00000563707
resolver
ensp
ENSP00000563708
resolver
ensp
ENSP00000563709
resolver
ensp
ENSP00000563710
resolver
ensp
ENSP00000563713
resolver
ensp
ENSP00000563714
resolver
ensp
ENSP00000563715
resolver
ensp
ENSP00000563716
resolver
ensp
ENSP00000563717
resolver
ensp
ENSP00000563719
resolver
ensp
ENSP00000563720
resolver
ensp
ENSP00000563721
resolver
ensp
ENSP00000563722
resolver
ensp
ENSP00000563725
resolver
ensp
ENSP00000563726
resolver
ensp
ENSP00000563727
resolver
ensp
ENSP00000563728
resolver
ensp
ENSP00000563729
resolver
ensp
ENSP00000563730
resolver
ensp
ENSP00000563731
resolver
ensp
ENSP00000563732
resolver
ensp
ENSP00000635582
resolver
ensp
ENSP00000635583
resolver
ensp
ENSP00000635584
resolver
ensp
ENSP00000635585
resolver
ensp
ENSP00000635586
resolver
ensp
ENSP00000635588
resolver
ensp
ENSP00000635590
resolver
ensp
ENSP00000635591
resolver
ensp
ENSP00000635592
resolver
ensp
ENSP00000635593
resolver
ensp
ENSP00000635594
resolver
ensp
ENSP00000635595
resolver
ensp
ENSP00000635596
resolver
ensp
ENSP00000635597
resolver
ensp
ENSP00000635601
resolver
ensp
ENSP00000635602
resolver
ensp
ENSP00000635603
resolver
ensp
ENSP00000635604
resolver
ensp
ENSP00000635605
resolver
ensp
ENSP00000635607
resolver
ensp
ENSP00000635608
resolver
ensp
ENSP00000635610
resolver
ensp
ENSP00000635611
resolver
ensp
ENSP00000635613
resolver
ensp
ENSP00000635614
resolver
ensp
ENSP00000635616
resolver
ensp
ENSP00000635617
resolver
enst
ENST00000308874
resolver
enst
ENST00000371698
resolver
enst
ENST00000371699
resolver
enst
ENST00000406555
resolver
enst
ENST00000893633
resolver
enst
ENST00000893634
resolver
enst
ENST00000893635
resolver
enst
ENST00000893636
resolver
enst
ENST00000893637
resolver
enst
ENST00000893638
resolver
enst
ENST00000893639
resolver
enst
ENST00000893640
resolver
enst
ENST00000893641
resolver
enst
ENST00000893642
resolver
enst
ENST00000893643
resolver
enst
ENST00000893644
resolver
enst
ENST00000893645
resolver
enst
ENST00000893646
resolver
enst
ENST00000893647
resolver
enst
ENST00000893648
resolver
enst
ENST00000893649
resolver
enst
ENST00000893650
resolver
enst
ENST00000893651
resolver
enst
ENST00000893654
resolver
enst
ENST00000893655
resolver
enst
ENST00000893656
resolver
enst
ENST00000893657
resolver
enst
ENST00000893658
resolver
enst
ENST00000893660
resolver
enst
ENST00000893661
resolver
enst
ENST00000893662
resolver
enst
ENST00000893666
resolver
enst
ENST00000893667
resolver
enst
ENST00000893668
resolver
enst
ENST00000893669
resolver
enst
ENST00000893670
resolver
enst
ENST00000893671
resolver
enst
ENST00000893672
resolver
enst
ENST00000893673
resolver
enst
ENST00000965523
resolver
enst
ENST00000965524
resolver
enst
ENST00000965525
resolver
enst
ENST00000965526
resolver
enst
ENST00000965527
resolver
enst
ENST00000965531
resolver
enst
ENST00000965532
resolver
enst
ENST00000965533
resolver
enst
ENST00000965534
resolver
enst
ENST00000965535
resolver
enst
ENST00000965536
resolver
enst
ENST00000965537
resolver
enst
ENST00000965538
resolver
enst
ENST00000965542
resolver
enst
ENST00000965543
resolver
enst
ENST00000965544
resolver
enst
ENST00000965545
resolver
enst
ENST00000965546
resolver
enst
ENST00000965548
resolver
enst
ENST00000965549
resolver
enst
ENST00000965551
resolver
enst
ENST00000965552
resolver
enst
ENST00000965554
resolver
enst
ENST00000965555
resolver
enst
ENST00000965557
resolver
enst
ENST00000965558
resolver
genesymbol
EGFL7
resolver
genesymbol_syn
MEGF7
resolver
hgnc
HGNC:20594
resolver
uniprot
B3KRP0
resolver
uniprot
M9VTX9
resolver
uniprot
Q5M7Y5
resolver
uniprot
Q5VUD5
resolver
uniprot
Q96EG0
resolver
uniprot_entry
EGFL7_HUMAN
resolver
uniprot_sec
B3KRP0
resolver
uniprot_sec
M9VTX9
resolver
uniprot_sec
Q5M7Y5
resolver
uniprot_sec
Q5VUD5
resolver
uniprot_sec
Q96EG0
resolver
amino_acid_sequence
MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLLVHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS
uniprot
proteins
function
FUNCTION: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis. {ECO:0000269|PubMed:23386126, ECO:0000269|PubMed:23639441}.
uniprot
proteins
mass_dalton
29618
uniprot
proteins
mutagenesis
MUTAGEN 131; /note="G->A: Disrupts RGD motif and results in a 79% loss of cell adhesion."; /evidence="ECO:0000269|PubMed:23386126
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
23386126
uniprot
proteins
pubmed
23639441
uniprot
proteins
sequence_length
273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000269|PubMed:23386126}.
uniprot
proteins