STXBP3
entrez
6814
canonical
uniprot
O00186
canonical
ensembl
ENSG00000116266
resolver
ensp
ENSP00000359025
resolver
enst
ENST00000370008
resolver
genesymbol
STXBP3
resolver
hgnc
HGNC:11446
resolver
uniprot
A8K269
resolver
uniprot
A8K5K7
resolver
uniprot
Q53FW1
resolver
uniprot
Q86YJ3
resolver
uniprot
Q9UPD7
resolver
uniprot_entry
STXB3_HUMAN
resolver
uniprot_sec
A8K269
resolver
uniprot_sec
A8K5K7
resolver
uniprot_sec
Q53FW1
resolver
uniprot_sec
Q86YJ3
resolver
uniprot_sec
Q9UPD7
resolver
amino_acid_sequence
MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE
uniprot
proteins
function
FUNCTION: Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. {ECO:0000250}.
uniprot
proteins
mass_dalton
67764
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4. {ECO:0000269|PubMed:10194441}.
uniprot
proteins
protein_family
STXBP/unc-18/SEC1 family
uniprot
proteins
pubmed
10194441
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8824310
uniprot
proteins
sequence_length
592
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:10194441}. Cell membrane {ECO:0000269|PubMed:10194441}. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated.
uniprot
proteins