Myl9
entrez
296313
canonical
uniprot
Q64122
canonical
ensembl
ENSRNOG00000020246
resolver
ensp
ENSRNOP00000027445
resolver
enst
ENSRNOT00000027445
resolver
genesymbol
Myl9
resolver
genesymbol_syn
Myrl2
resolver
uniprot
B0BMS8
resolver
uniprot
F7F3J1
resolver
uniprot_entry
B0BMS8_RAT
resolver
uniprot_entry
F7F3J1_RAT
resolver
uniprot_entry
MYL9_RAT
resolver
amino_acid_sequence
MSSKRAKAKTTKKRPQSATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEXLEGMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYRERIDKKGNFNYVEFTRILKHGAKDKDD
uniprot
proteins
function
FUNCTION: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity). {ECO:0000250|UniProtKB:P24844, ECO:0000250|UniProtKB:Q9CQ19}.
uniprot
proteins
mass_dalton
19721
uniprot
proteins
post_translational_modification
PTM: Phosphorylation by MLCK/MYLK increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge. Phosphorylation is required for myotube formation. Phosphorylated by DAPK3; DAPK3-mediated phosphorylation is inhibited by LUZP1. {ECO:0000250|UniProtKB:P24844}.
uniprot
proteins
pubmed
7733921
uniprot
proteins
pubmed
8702756
uniprot
proteins
sequence_length
171
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9CQ19}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9CQ19}. Note=Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts. {ECO:0000250|UniProtKB:Q9CQ19}.
uniprot
proteins