NTF4
entrez
4909
canonical
uniprot
P34130
canonical
ensembl
ENSG00000225950
resolver
ensp
ENSP00000469455
resolver
ensp
ENSP00000471508
resolver
ensp
ENSP00000512384
resolver
ensp
ENSP00000512385
resolver
ensp
ENSP00000512386
resolver
ensp
ENSP00000512387
resolver
ensp
ENSP00000512388
resolver
ensp
ENSP00000577886
resolver
ensp
ENSP00000609748
resolver
enst
ENST00000593537
resolver
enst
ENST00000594938
resolver
enst
ENST00000595857
resolver
enst
ENST00000696088
resolver
enst
ENST00000696089
resolver
enst
ENST00000696090
resolver
enst
ENST00000696091
resolver
enst
ENST00000907827
resolver
enst
ENST00000939689
resolver
genesymbol
NTF4
resolver
genesymbol_syn
NTF5
resolver
hgnc
HGNC:8024
resolver
uniprot
Q6FH56
resolver
uniprot_entry
NTF4_HUMAN
resolver
uniprot_sec
Q6FH56
resolver
amino_acid_sequence
MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
uniprot
proteins
disease_involvement
DISEASE: Glaucoma 1, open angle, O (GLC1O) [MIM:613100]: A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. However, glaucoma can occur at any intraocular pressure. The disease is generally asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. {ECO:0000269|PubMed:19765683, ECO:0000269|PubMed:20215012}. Note=Disease susceptibility may be associated with variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Target-derived survival factor for peripheral sensory sympathetic neurons (PubMed:1742028). May promote ameloblast differentiation and subsequent reduction in proliferation of ameloblasts (By similarity). {ECO:0000250|UniProtKB:Q80VU4, ECO:0000269|PubMed:1742028}.
uniprot
proteins
mass_dalton
22427
uniprot
proteins
protein_family
NGF-beta family
uniprot
proteins
pubmed
10631974
uniprot
proteins
pubmed
1313578
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1742028
uniprot
proteins
pubmed
19765683
uniprot
proteins
pubmed
20215012
uniprot
proteins
sequence_length
210
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1742028}.
uniprot
proteins