Rreb1
entrez
68750
canonical
uniprot
Q3UH06
canonical
ensembl
ENSMUSG00000039087
resolver
ensp
ENSMUSP00000049265
resolver
ensp
ENSMUSP00000105866
resolver
ensp
ENSMUSP00000105867
resolver
ensp
ENSMUSP00000115599
resolver
ensp
ENSMUSP00000121211
resolver
ensp
ENSMUSP00000169166
resolver
ensp
ENSMUSP00000169168
resolver
genesymbol
Rreb1
resolver
uniprot
B8JJE2
resolver
uniprot
B8JJE3
resolver
uniprot
Q3TB97
resolver
uniprot
Q4ZE88
resolver
uniprot
Q66JZ8
resolver
uniprot_entry
RREB1_MOUSE
resolver
uniprot_sec
B8JJE2
resolver
uniprot_sec
B8JJE3
resolver
uniprot_sec
Q3TB97
resolver
uniprot_sec
Q4ZE88
resolver
uniprot_sec
Q66JZ8
resolver
amino_acid_sequence
MTSNSPIGLEGSDLSSINTMMSAVMSVASVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHACSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDTNSTTAAAPPSPLKRRRLSSKRKLSHDAESEDPGPAKKMVEDGQSGDLDKMSDEIFHCPVCFKEFVCKYELETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLSSLILHRQSHIPADQGREKLQTKTLAAESLEQKAFLALLGLQHTKDVKPAPAEELLPDDNQAIQLQTLKYQLPQEPGCPTVLSVSPLDAASLGGSLTVLPATKENMKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPLSKAPATPLQAIFKHMPPLKPKPLVTPRTVVAASTPPPLINAQQASPGCISPSLPPQSLKFLKGSVEAVSNVHLLQSKSGIQPSTTTQLFLQQAGVELPGQPEMKTQLEQESIIEALLPLNMEAKIKQEITEGDLKAIMTGPSGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHIRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSPTAELVDAFCAPETVCRLCGEDLKHYRALRIHMRTHCSRGLGGCHKGRKPFECKECNAPFVAKRNCIHHILKQHLHVPEKDIESYVLATNSGLGPADTPTDAASRGEEGSCVTFAECKPLATFLEPQNGFLHSSPTQPLPSHISVKLEPASSFAMDFNEPLDFSQKGLALVQVKQENVSSLLTSSSSSALYDCSMEPIDLSIPKSVKKGDKDTVVPSDAKKPEPEAGQAEPLSPRPPPCPTLSVTVEPKGSLETPTGTVVAVTTAAKLEPHTQPLQGSVQLAVPIYSPALVSNTPLLGNSAALLNNPALLRPLRPKPPLLLPKPSMTEELPPLASIAQIISSVSSAPTLLKTKVADPGPSITSSNTVATDSPGSSIPKAAATPTDTTSSKESSEPPPAASSPEEALPTEQGPAATSSSRKRGRKRGLRNRPLPNSSAVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDDTQEEVAGAPADQHGPADEEQGSPAEDRLLRAKRNSYANCLQKINCPHCPRVFPWASSLQRHMLTHTDSQSDTDTLTTPGEVLDLTAQAKEQPPAEGASEISPASQDLAIKEAKAAAAPSEEEEEKETEENPEPEEECRVEESTGAADAPEEDTASNQSLDLDFATKLMDFKLAESEAGSVDSQGPAQQEPKHACDTCGKNFKFLGTLSRHKKAHSCQEPKEEEAAAPSLENEGVGRAVEGPSPSPEPEEKPAESLAIDPTPGTREASVAKQNEETEGPTDGEGTAEKRGDGDKRPKTDSPKSMASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHSKHHGKDSDKDERAEEDSEDESTHSATNPASENEAESAPSTSNHVAVTRSRKESLSTSGKECSPEERAAAEQAAEPSAPKEQASPGETDPQSPAAIVQDLLELCGKRPAPILAATDGASQLLGME
uniprot
proteins
function
FUNCTION: Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters (PubMed:12700664). Represses the angiotensinogen gene (By similarity). Negatively regulates the transcriptional activity of AR (By similarity). Potentiates the transcriptional activity of NEUROD1 (By similarity). Binds specifically to the allelic variant of the CDKN2A promoter present in Balb/c mice, which leads to a down-regulation of CDKN2A expression in this strain, and, as a consequence, to an elevated susceptibility to pristane-induced tumors (PubMed:12700664). Promotes brown adipocyte differentiation (PubMed:27923061). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (By similarity). {ECO:0000250|UniProtKB:Q92766, ECO:0000269|PubMed:12700664, ECO:0000269|PubMed:27923061}.
uniprot
proteins
mass_dalton
184154
uniprot
proteins
protein_family
Krueppel C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
12700664
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27923061
uniprot
proteins
sequence_length
1700
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000250}.
uniprot
proteins