Tdrd12
entrez
71981
canonical
uniprot
Q9CWU0
canonical
ensembl
ENSMUSG00000030491
resolver
ensp
ENSMUSP00000032701
resolver
ensp
ENSMUSP00000140328
resolver
ensp
ENSMUSP00000141796
resolver
ensp
ENSMUSP00000343749
resolver
genesymbol
Tdrd12
resolver
genesymbol_syn
Ecat8
resolver
genesymbol_syn
Repro23
resolver
uniprot_entry
TDR12_MOUSE
resolver
amino_acid_sequence
MFEVLVLKIEDPGCFWVIIKGCSHFLEQEVDYQKLNTAMNDFYNSMCQDVEMKPLMLEEGQVCVVYCQELKCWCRALIKSIISSADHYLAECFLVDFAKYIPVKSKNIRVAVESFMQLPYRAKKFRLYGTKPVTLHIDFCEDNAEIVPATKWDSAAIQYFQNLLRATTQVEAKLCAVEEDTFEVYLYATIKNEKVCVNDDLVAKNFAYYVSPMGNKNLNPLEKPRQSLNSVTCSSKLSPSLTLWPMLLQGKDYHRMENKALNYKDSLTDSPKMMLEKQQQSLPLKHTEKCTESSVYWPTKRGITIYADPDVPSVSGSSQRPNEKPLRLTEKKDCDEKNGCVKLLQFLNPDPLRADGTSDLHQLQKVKLGTLQPGVVLRNRIEPCLTLEKSPLSADLKKMALTCLNSDTEDMKVAMEEMIPPEALQRNKFPGPSHTASYSWPPIARGCDMVVISHCGNDPLLYLPPLLTILQMGGCYKSLPSRNGPLAVIVCPGWKKAQFIFELLGDYSMSSRPLHPVLLTIGLHKDEAKNMKLPRGCDVIVTTPHSLLRLLTYRSLLFLRLCHLVLDEVHMLFFEANEQMFAILDNFKKNVEVEERESAPHQIVAVGVHWNKHIDHLVREFMKDPCVVITALEEAALYGSVQQVVHLCLECEKTSTLLQVLDFVPSQAQKTLIFTCSVAETETVCKGSPAEQGDKKTKSVLLLTERNASHAVGILRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNKTLPVFGHIRVIPFYISNATNYFGRIIDKHVDLYETLNAEMNEYFKESSNKTSAEKVENLGLYGLEEKTLFQRVQVLEVSQKEDTWGLGSILVKLIDEGRTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHHKIVGKMHDAKVVLALGNTLWIDPMVHVTKLSNLKTSIIDYNVRAEILSMGMGIDNSEHLEQLKKLYKEAKLPAFEDLPCQTSIPTTVEDTVCLQGTQQGDGGTERGAGSQEDSDNQKPGVLSEDIGSETISSAPQPHGRSFHPQIKWFQKDDVVILKIKIRNVKDYKCKFFTDRVIFSAWVGDKFYLADLELQGDIRKDDCKCIIKDDEPLITLAKEKQECWCGLLKQRNPNVAFDFDHWEECEEDSPFSKVVNSKNLSCKVAALAESSGSSSDTTDGSESE
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (PubMed:24067652). Involved in the secondary piRNAs metabolic process (PubMed:24067652). Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs (PubMed:26669262). {ECO:0000269|PubMed:24067652, ECO:0000269|PubMed:26669262}.
uniprot
proteins
mass_dalton
137627
uniprot
proteins
pubmed
12787504
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24067652
uniprot
proteins
pubmed
26669262
uniprot
proteins
sequence_length
1215
uniprot
proteins