MED30
entrez
90390
canonical
uniprot
Q96HR3
canonical
ensembl
ENSG00000164758
resolver
ensp
ENSP00000297347
resolver
ensp
ENSP00000431051
resolver
ensp
ENSP00000796709
resolver
genesymbol
MED30
resolver
genesymbol_syn
THRAP6
resolver
genesymbol_syn
TRAP25
resolver
hgnc
HGNC:23032
resolver
uniprot
C6GKU9
resolver
uniprot_entry
MED30_HUMAN
resolver
uniprot_sec
C6GKU9
resolver
amino_acid_sequence
MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQLPNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEEDGSKNDDRAGPPRFASEERREIAEVNKKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:11909976, ECO:0000269|PubMed:16595664}.
uniprot
proteins
mass_dalton
20277
uniprot
proteins
protein_family
Mediator complex subunit 30 family
uniprot
proteins
pubmed
11909976
uniprot
proteins
pubmed
12584197
uniprot
proteins
pubmed
15175163
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15989967
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
16595664
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
178
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins