Tdrd5
entrez
289129
canonical
uniprot
B4F7C4
canonical
ensembl
ENSRNOG00000004018
resolver
ensp
ENSRNOP00000005353
resolver
ensp
ENSRNOP00000075564
resolver
enst
ENSRNOT00000005353
resolver
genesymbol
Tdrd5
resolver
uniprot
A0A0H2UHC6
resolver
uniprot_entry
A0A0H2UHC6_RAT
resolver
uniprot_entry
TDRD5_RAT
resolver
amino_acid_sequence
MSEQERIQDCLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIASLVAKQRRSHKVRNSMQKGRSSVCSGRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFEKAFARRFGRSFQYMQYGFLSMFEVLSAASDVICVEQTRAGSLLTLKKSASEEKQREWPAGKIFTQPFRMKQQGSYSTGFPVTKTRFSQPISNMEPPKQVLSMEKIPMFNTVEASRLSHTEKLNQLESTFKSVIAQIGPGGTVDPDLKHKIKFVVSKFPQGLFISKLLGEFELVFKEQLSPKQLGFLNVTELVGALSDILRVEFSEEKQDLLVFDADLRPLLPAGPLSSVRNSCLVQPDKRIEANAWASSPSRNSLSTVAVKKTTWDCPLKNHKEAEQKAYKKPNLVVKPLQLQVETNKSQLSLSMANHDIPPDAVRAKKLCRLPPLDTSTLVGVFVEYIISPSQFYVRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPEYFIQPGHLCCVRISEDKWWYRVIIHRILGKKEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPAEEHWTSKAILHFQKLCGLKPLVGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENAPSKGFRDFNPPALYTNSSAAPGDMVLTELGHPAQQHYLNEDGEILQQPQQDINDEKSISHLKSVSEELLKDSKLGPLKTRESCEEEPQWSILKPKDPKEENEDEVPTGMPCLESVTIGDDIWDENWLPLQAKMGKAGGPASHLFTSSLVGKKQYQTRGETTRKDWCFSTSKDIWDDSWQPLGLANDVKGRTHTPEGPIAQEKNIGTTRIRKQPDLQYPLDSSTLPKLEEFYISLIKSQQSAEGSQSEPASIQTPLKPGQASSTAPSSTPAAGDSPENHSGSAPDFSEALHSSKYSHGCLGSSCAVSHVQEPPALVPQCERREA
uniprot
proteins
function
FUNCTION: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
111327
uniprot
proteins
protein_family
TDRD5 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
995
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. {ECO:0000250}.
uniprot
proteins