Dlx2
entrez
13392
canonical
uniprot
P40764
canonical
ensembl
ENSMUSG00000023391
resolver
ensp
ENSMUSP00000024159
resolver
enst
ENSMUST00000024159
resolver
genesymbol
Dlx2
resolver
genesymbol_syn
Tes-1
resolver
genesymbol_syn
Tes1
resolver
uniprot
Q52KJ2
resolver
uniprot_entry
DLX2_MOUSE
resolver
uniprot_entry
Q52KJ2_MOUSE
resolver
amino_acid_sequence
MTGVFDSLVADMHSTQITASSTYHQHQQPPSGAGAGPGGNSNSSSSNSSLHKPQESPTLPVSTATDSSYYTNQQHPAGGGGGGASPYAHMGSYQYHASGLNNVSYSAKSSYDLGYTAAYTSYAPYGTSSSPVNNEPDKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPTEQHPGASASPPCASPPVSAPASWDFGAPQRMAGGGPGSGGGGAGSSGSSPSSAASAFLGNYPWYHQASGSASHLQATAPLLHPSQTPQAHHHHHHHHHAGGGAPVSAGTIF
uniprot
proteins
function
FUNCTION: Acts as a transcriptional activator (PubMed:21875655). Activates transcription of CGA/alpha-GSU, via binding to the downstream activin regulatory element (DARE) in the gene promoter (PubMed:23371388). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (PubMed:21875655). Likely to play a regulatory role in the development of the ventral forebrain (PubMed:1678612). May play a role in craniofacial patterning and morphogenesis (PubMed:1678612). {ECO:0000269|PubMed:1678612, ECO:0000269|PubMed:21875655, ECO:0000269|PubMed:23371388}.
uniprot
proteins
mass_dalton
34746
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by serine/threonine kinases.
uniprot
proteins
protein_family
Distal-less homeobox family
uniprot
proteins
pubmed
1632970
uniprot
proteins
pubmed
1678612
uniprot
proteins
pubmed
1687503
uniprot
proteins
pubmed
21875655
uniprot
proteins
pubmed
23371388
uniprot
proteins
pubmed
7893603
uniprot
proteins
pubmed
8098616
uniprot
proteins
pubmed
8812481
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins