PSMD8
entrez
5714
canonical
uniprot
P48556
canonical
ensembl
ENSG00000099341
resolver
ensp
ENSP00000215071
resolver
enst
ENST00000215071
resolver
genesymbol
HEL-S-91n
resolver
genesymbol
PSMD8
resolver
hgnc
HGNC:9566
resolver
uniprot
B4DX18
resolver
uniprot
Q6P1L7
resolver
uniprot
V9HW09
resolver
uniprot_entry
PSMD8_HUMAN
resolver
uniprot_entry
V9HW09_HUMAN
resolver
uniprot_sec
B4DX18
resolver
uniprot_sec
Q6P1L7
resolver
amino_acid_sequence
MFIKGRAPRAPPRERRRATRGGLRQVVAPPRALGSTSRPHFRRASVCRRRCRKSGGLLAASRKMAAAAVNGAAGFSSSGPAATSGAVLQAATGMYEQLKGEWNRKSPNLSKCGEELGRLKLVLLELNFLPTTGTKLTKQQLILARDILEIGAQWSILRKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLPAKDIQTNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFTEATRILFFNTPKKMTDYAKKRGWVLGPNNYYSFASQQQKPEDTTIPSTELAKQVIEYARQLEMIV
uniprot
proteins
function
FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. {ECO:0000269|PubMed:1317798}.
uniprot
proteins
mass_dalton
39612
uniprot
proteins
protein_family
Proteasome subunit S14 family
uniprot
proteins
pubmed
1317798
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17323924
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
27342858
uniprot
proteins
pubmed
27428775
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
29290612
uniprot
proteins
pubmed
7621825
uniprot
proteins
sequence_length
350
uniprot
proteins