Chst3
entrez
84468
canonical
uniprot
Q9QZL2
canonical
ensembl
ENSRNOG00000000572
resolver
ensp
ENSRNOP00000000697
resolver
enst
ENSRNOT00000000697
resolver
genesymbol
Chst3
resolver
uniprot
F1LN90
resolver
uniprot_entry
CHST3_RAT
resolver
uniprot_entry
F1LN90_RAT
resolver
amino_acid_sequence
MEKGLALPQDCRDLVHNLKIRGRYVLFLAFVVIVFIFIEKENKIISRVSDKLKQIPQFVADANSTDPALLLSENASLLSLSELDSTFSHLRSRLHNLSLQLGIAPAMEAQGQEAVAEKPSQQAGAGTRRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVFFQQGGASAAGSALVYRDVLKQLLLCDLYVLEPFISPPPEDHLTQFLFRRGSSRSLCEDPVCTPFVKKVFEKYHCRNRHCGPLNVTLAAEACRRKDHMALKVVRIRQLEFLQPLAEDPRLDLRVIQLVRDPRAVLASRMVAFAGKYESWKKWLSEGQDQLSENEVQRLRGNCENIRLSAELGLRQPAWLRGRYMLVRYEDVARRPLQKAREMYRSAGIPLTPQVEDWIQKNTQAARDSSDVYSTQKNSSEQFEKWRFSIPFKLAQVVQAVCGPAMHLFGHKLAKDTASLTNRSISLLEERGTFWVT
uniprot
proteins
ec_number
2.8.2.17
uniprot
proteins
ec_number
2.8.2.21
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Catalyzes with a lower efficiency the sulfation of Gal residues of keratan sulfate, another glycosaminoglycan (By similarity). Can also catalyze the sulfation of the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides (By similarity). May play a role in the maintenance of naive T-lymphocytes in the spleen (By similarity). {ECO:0000250|UniProtKB:O88199, ECO:0000250|UniProtKB:Q7LGC8, ECO:0000250|UniProtKB:Q92179}.
uniprot
proteins
mass_dalton
54018
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q92179}.
uniprot
proteins
protein_family
Gal/GlcNAc/GalNAc subfamily
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
sequence_length
474
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..38; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins