Plekha7
entrez
233765
canonical
uniprot
Q3UIL6
canonical
ensembl
ENSMUSG00000045659
resolver
ensp
ENSMUSP00000081714
resolver
ensp
ENSMUSP00000138214
resolver
ensp
ENSMUSP00000138257
resolver
ensp
ENSMUSP00000138544
resolver
ensp
ENSMUSP00000138575
resolver
ensp
ENSMUSP00000138766
resolver
ensp
ENSMUSP00000145894
resolver
genesymbol
Plekha7
resolver
genesymbol_syn
Hadp1
resolver
uniprot
B6RSP2
resolver
uniprot
B6RSP3
resolver
uniprot
Q3TUE4
resolver
uniprot
Q5XG70
resolver
uniprot
Q8BYE3
resolver
uniprot_entry
PKHA7_MOUSE
resolver
uniprot_sec
B6RSP2
resolver
uniprot_sec
B6RSP3
resolver
uniprot_sec
Q3TUE4
resolver
uniprot_sec
Q5XG70
resolver
uniprot_sec
Q8BYE3
resolver
amino_acid_sequence
MAAAVGRDTLPEHWSYGVCRDGRVFFINDQLRCTTWLHPRTGEPVNSGHMIRSDLPRGWEEGFTEEGASFFIDHNQQTTTFRHPVTGQFSSENSEYVLREEPHPHMSKPERNQRPSSMVSETSTAGTTSTLEAKPGPKIVKSSSKVHSFGKRDQAIRRNLNVPVVVRGWLHKQDSSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISPVAPEDRISRKYSFKAVHTGMRALIYSTTTAGSQMEHSGMRTYYFSADTLEDMNAWVRAMNQAAQVLSRSSLRRDVDKVERQAMPQANHTDACQECGHVGPGHSRDCPRRGYEDSYGFNRREQEEERFRAQRDPLEGRRDRSKARSPYLPAEEDALFVDLPGGPRGQQAQPQRAEKNGVPPYGLGEQNGTNGYQRTAPPRANPEKHSQRKTGLAQAEHWTKAQKGDGRSLPLDQTLPRQGPSQPLSFPENYQSLPKSTRHLSGSSSPPPRNLPSDYKYAQDRASHLKMSSEERRAHRDGTVWQLYEWQQRQQFRHGSPTAPIGAGSPEFTEQGRSRSLLEVPRSISVPPSPSDIPPPGPPRPFPPRRPHTPAERVTVKPPEQRRSVDISLGGSPRKARGHAAKNSSHVDRRSMPSMGYMTHTVSAPSLHGKSADDTYLQLKKDLEYLDLKMTGRDLLKDRSLKPMKIAESDIDVKLSIFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQTEQYRDQPQHLEKITCQQRLLQEDLVHIRAELCRESTEMENAWNEYLKLEKDVEQLKQTLQEQHRRAFFFQEKSQIQKDLWRIEDVMAGLSANKENYRVLVGSVKNPERKTVPLFPHPSVPSLSPTESKPALQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVMSPLQSPTKAKPQAEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDREQGQCVNGDLKVELRSYVSEPELASLSGDVPQPSLSLVGSESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAENSSATFSRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLSQGEKTGLLSARYLSQPLPGDLGSVC
uniprot
proteins
function
FUNCTION: Required for zonula adherens biogenesis and maintenance. Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site (By similarity). Mediates docking of ADAM10 to zonula adherens through a PDZD11-dependent interaction with the ADAM10-binding protein TSPAN33 (PubMed:30463011). {ECO:0000250|UniProtKB:Q6IQ23, ECO:0000269|PubMed:30463011}.
uniprot
proteins
mass_dalton
126742
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30463011
uniprot
proteins
sequence_length
1118
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, adherens junction {ECO:0000269|PubMed:30463011}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q6IQ23}. Note=Localizes to zonula adherens, recruited via its interaction with CTNND1. {ECO:0000250|UniProtKB:Q6IQ23}.
uniprot
proteins