Slc43a1
entrez
72401
canonical
uniprot
Q8BSM7
canonical
ensembl
ENSMUSG00000027075
resolver
ensp
ENSMUSP00000028469
resolver
ensp
ENSMUSP00000107251
resolver
ensp
ENSMUSP00000107252
resolver
ensp
ENSMUSP00000112642
resolver
ensp
ENSMUSP00000330153
resolver
enst
ENSMUST00000028469
resolver
enst
ENSMUST00000111624
resolver
enst
ENSMUST00000111625
resolver
enst
ENSMUST00000121114
resolver
genesymbol
Slc43a1
resolver
genesymbol_syn
Lat3
resolver
uniprot
A2ATS3
resolver
uniprot
A2ATS4
resolver
uniprot
G3X8X3
resolver
uniprot
Q9D0H7
resolver
uniprot_entry
A2ATS4_MOUSE
resolver
uniprot_entry
G3X8X3_MOUSE
resolver
uniprot_entry
LAT3_MOUSE
resolver
uniprot_sec
A2ATS3
resolver
uniprot_sec
Q9D0H7
resolver
amino_acid_sequence
MAPTLKQAYRRRWWMACTAVVENLFFSAVLLGWASLLIMLKKEGFYSSLCPAENRTNTTQDEQHQWTSCDQQEKMLNLGFTIGSFLLSATTLPLGILMDRFGPRPLRLVGSACFAASCTLMALASRDTEVLSPLIFLALSLNGFAGICLTFTSLTLPNMFGNLRSTFMALMIGSYASSAITFPGIKLIYDAGVPFTVIMFTWSGLACLIFLNCALNWPAEAFPAPEEVDYTKKIKLIGLALDHKVTGDRFYTHVTIVGQRLSQKSPSLEEGADAFISSPDIPGTSEETPEKSVPFRKSLCSPIFLWSLVTMGMTQLRVIFYMGAMNKILEFIVTGGKERETNEQRQKVEETVEFYSSIFGVMQLLCLLTCPLIGYIMDWRIKDCVDAPTEGTLNENASFGDARDGASTKFTRPRYRKVQKLTNAINAFTLTNILLVGFGIACLIKNLHLQLLAFVLHTIVRGFFHSACGGLYAAVFPSNHFGTLTGLQSLISAVFALLQQLLFMAMVGPLHGDPFWVNLGLLLLSFLGFLLPSYLYYYRSRLQREYATNLVDPQKVLNTSKVAT
uniprot
proteins
function
FUNCTION: Uniport that mediates the transport of neutral amino acids such as L-leucine, L-isoleucine, L-valine, and L-phenylalanine (PubMed:17322374). The transport activity is sodium ions-independent, electroneutral and mediated by a facilitated diffusion (PubMed:17322374). Mediates the efflux of 3,3'-diiodo-L-thyronine (3,3'-T2) and 3-iodo-L-tyrosine (MIT) (By similarity). {ECO:0000250|UniProtKB:O75387, ECO:0000269|PubMed:17322374}.
uniprot
proteins
mass_dalton
62644
uniprot
proteins
protein_family
SLC43A transporter (TC 2.A.1.44) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17322374
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
19443642
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
564
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17322374}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:O75387}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:17322374}; Multi-pass membrane protein {ECO:0000255}. Note=Located in the apical plasma membrane of the podocyte foot processes (By similarity). Located in the plasma membrane of liver and skeletal muscle, and in the endoplasmic reticulum and in crystalline inclusions in pancreatic acinar cells (PubMed:17322374). {ECO:0000250|UniProtKB:O75387, ECO:0000269|PubMed:17322374}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..40; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 78..98; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 105..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..151; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 191..211; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 303..323; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 357..377; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 424..444; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 451..471; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 490..510; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 515..535; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins