SYT12
entrez
91683
canonical
uniprot
Q8IV01
canonical
ensembl
ENSG00000173227
resolver
ensp
ENSP00000377520
resolver
ensp
ENSP00000431400
resolver
ensp
ENSP00000435316
resolver
ensp
ENSP00000561925
resolver
ensp
ENSP00000602846
resolver
ensp
ENSP00000602847
resolver
ensp
ENSP00000602848
resolver
ensp
ENSP00000602849
resolver
ensp
ENSP00000615391
resolver
ensp
ENSP00000615392
resolver
ensp
ENSP00000615393
resolver
ensp
ENSP00000615394
resolver
enst
ENST00000393946
resolver
enst
ENST00000525457
resolver
enst
ENST00000527043
resolver
enst
ENST00000891866
resolver
enst
ENST00000932787
resolver
enst
ENST00000932788
resolver
enst
ENST00000932789
resolver
enst
ENST00000932790
resolver
enst
ENST00000945332
resolver
enst
ENST00000945333
resolver
enst
ENST00000945334
resolver
enst
ENST00000945335
resolver
genesymbol
SYT12
resolver
hgnc
HGNC:18381
resolver
uniprot
B0AZL9
resolver
uniprot_entry
B0AZL9_HUMAN
resolver
uniprot_entry
SYT12_HUMAN
resolver
amino_acid_sequence
MAVDVAEYHLSVIKSPPGWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYRYLQQKYGESCAEAREKRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAVRRN
uniprot
proteins
function
FUNCTION: Synaptic vesicle phosphoprotein that enhances spontaneous neurotransmitter release but does not effect induced neurotransmitter release (By similarity). Unlike other synaptotagmins, it does not bind Ca(2+) or phospholipids (By similarity). Essential for mossy-fiber long-term potentiation in the hippocampus (By similarity). {ECO:0000250|UniProtKB:P97610, ECO:0000250|UniProtKB:Q920N7}.
uniprot
proteins
mass_dalton
46537
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Ser-97 is required for mossy-fiber long-term potentiation. {ECO:0000250|UniProtKB:Q920N7}.
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
421
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:P97610}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins