Deup1
entrez
315438
canonical
uniprot
Q5U3Z6
canonical
ensembl
ENSRNOG00000061247
resolver
ensp
ENSRNOP00000072022
resolver
ensp
ENSRNOP00000090446
resolver
ensp
ENSRNOP00000108386
resolver
enst
ENSRNOT00000089364
resolver
genesymbol
Deup1
resolver
genesymbol_syn
Ccdc67
resolver
uniprot
A0A8L2R4Y5
resolver
uniprot_entry
A0A8L2R4Y5_RAT
resolver
uniprot_entry
DEUP1_RAT
resolver
amino_acid_sequence
MENQAHTTAGASPCEAELQELMEQIDIMVSNKKLDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLVMTQNYEGQLQTLKAQFSKLTNNFEKLRLHQMKQNQSHRKEASNKDETPFELSSLNQKIEEFRAKSREWDKQEILYQTHLVSLDAQQKLLSEKCNQFQKQAQNYQTQLNGKQQRPEDSSPETPRLVCESSPGCEATQRDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKNELQSRDDLLRIIEMERLHLHRELLKMGELQTVQDNRKRVESSYSPSTKEPERKRKELFSVVSDQPNHEKELNKMRSQLYQEEDLCSEQERMRNEISELTQELHQKEVTIATIMKKAALLERQLKIELEIKEKMLAKQQISDRRYKAVRTENTHLKGMMGDLDPARYLTVDFSNKEHSRHTSINKLEYENERLRSDLAKLHINGKAAWSNQSSYEGAGAYIYQSQLKTETGGDRISEDCEMNRSPTPLSPLPFQTKEMTSPLAGDNEVLPLSPPDISFRASLAAQHFLMEEEKRAKELEKLLNTHIDELQRHTEFTLNKYTKLKQSRHI
uniprot
proteins
function
FUNCTION: Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
70105
uniprot
proteins
protein_family
CEP63 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
601
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes to the deuterosome. {ECO:0000250}.
uniprot
proteins