BEX3
entrez
27018
canonical
uniprot
Q00994
canonical
ensembl
ENSG00000166681
resolver
ensp
ENSP00000354843
resolver
ensp
ENSP00000361728
resolver
genesymbol
BEX3
resolver
genesymbol_syn
DXS6984E
resolver
genesymbol_syn
NADE
resolver
genesymbol_syn
NGFRAP1
resolver
hgnc
HGNC:13388
resolver
uniprot
B2RD17
resolver
uniprot
D3DXA3
resolver
uniprot
Q5JQT4
resolver
uniprot
Q5JQT5
resolver
uniprot_entry
BEX3_HUMAN
resolver
uniprot_sec
B2RD17
resolver
uniprot_sec
D3DXA3
resolver
uniprot_sec
Q5JQT4
resolver
uniprot_sec
Q5JQT5
resolver
amino_acid_sequence
MANIHQENEEMEQPMQNGEEDRPLGGGEGHQPAGNRRGQARRLAPNFRWAIPNRQINDGMGGDGDDMEIFMEEMREIRRKLRELQLRNCLRILMGELSNHHDHHDEFCLMP
uniprot
proteins
function
FUNCTION: May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. {ECO:0000250|UniProtKB:Q9WTZ9}.
uniprot
proteins
mass_dalton
12959
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated. Degraded by the proteasome. {ECO:0000250|UniProtKB:Q9WTZ9}.
uniprot
proteins
protein_family
BEX family
uniprot
proteins
pubmed
10764727
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
15958283
uniprot
proteins
pubmed
2171551
uniprot
proteins
sequence_length
111
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9WTZ9}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9WTZ9}. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria. {ECO:0000250|UniProtKB:Q9WTZ9}.
uniprot
proteins