Actc1
entrez
29275
canonical
uniprot
P68035
canonical
ensembl
ENSRNOG00000008536
resolver
ensembl
ENSRNOG00055002780
resolver
ensembl
ENSRNOG00060020335
resolver
ensembl
ENSRNOG00065015814
resolver
ensp
ENSRNOP00000011773
resolver
ensp
ENSRNOP00055003236
resolver
ensp
ENSRNOP00060028991
resolver
ensp
ENSRNOP00065020642
resolver
enst
ENSRNOT00000011773
resolver
enst
ENSRNOT00055004364
resolver
enst
ENSRNOT00060035264
resolver
enst
ENSRNOT00065026289
resolver
genesymbol
Actc1
resolver
genesymbol_syn
Actc
resolver
uniprot
A0JPJ4
resolver
uniprot
P04270
resolver
uniprot_entry
ACTC_RAT
resolver
uniprot_sec
A0JPJ4
resolver
uniprot_sec
P04270
resolver
amino_acid_sequence
MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
uniprot
proteins
mass_dalton
42019
uniprot
proteins
post_translational_modification
PTM: [Actin, alpha cardiac muscle 1, intermediate form]: N-terminal cleavage of acetylated cysteine of intermediate muscle actin by ACTMAP. {ECO:0000250|UniProtKB:P68033}.; PTM: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization. {ECO:0000250|UniProtKB:P68033}.; PTM: Monomethylation at Lys-86 (K86me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. {ECO:0000250|UniProtKB:P68032}.; PTM: Methylated at His-75 by SETD3. {ECO:0000250|UniProtKB:P68032}.
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
377
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
uniprot
proteins