Il18r1
entrez
16182
canonical
uniprot
Q61098
canonical
ensembl
ENSMUSG00000026070
resolver
ensp
ENSMUSP00000103679
resolver
ensp
ENSMUSP00000128277
resolver
ensp
ENSMUSP00000141695
resolver
enst
ENSMUST00000108044
resolver
enst
ENSMUST00000167723
resolver
enst
ENSMUST00000193391
resolver
genesymbol
Il18r1
resolver
uniprot
A0A0A6YWT9
resolver
uniprot
Q8C257
resolver
uniprot_entry
A0A0A6YWT9_MOUSE
resolver
uniprot_entry
IL18R_MOUSE
resolver
uniprot_entry
Q8C257_MOUSE
resolver
amino_acid_sequence
MHHEELILTLCILIVKSASKSCIHRSQIHVVEGEPFYLKPCGISAPVHRNETATMRWFKGSASHEYRELNNRSSPRVTFHDHTLEFWPVEMEDEGTYISQVGNDRRNWTLNVTKRNKHSCFSDKLVTSRDVEVNKSLHITCKNPNYEELIQDTWLYKNCKEISKTPRILKDAEFGDEGYYSCVFSVHHNGTRYNITKTVNITVIEGRSKVTPAILGPKCEKVGVELGKDVELNCSASLNKDDLFYWSIRKEDSSDPNVQEDRKETTTWISEGKLHASKILRFQKITENYLNVLYNCTVANEEAIDTKSFVLVRKEIPDIPGHVFTGGVTVLVLASVAAVCIVILCVIYKVDLVLFYRRIAERDETLTDGKTYDAFVSYLKECHPENKEEYTFAVETLPRVLEKQFGYKLCIFERDVVPGGAVVEEIHSLIEKSRRLIIVLSQSYLTNGARRELESGLHEALVERKIKIILIEFTPASNITFLPPSLKLLKSYRVLKWRADSPSMNSRFWKNLVYLMPAKAVKPWREESEARSVLSAP
uniprot
proteins
ec_number
3.2.2.6
uniprot
proteins
function
FUNCTION: Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (By similarity). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (PubMed:26099046). {ECO:0000250|UniProtKB:Q13478, ECO:0000269|PubMed:26099046}.
uniprot
proteins
mass_dalton
61601
uniprot
proteins
protein_family
Interleukin-1 receptor family
uniprot
proteins
pubmed
26099046
uniprot
proteins
pubmed
8626725
uniprot
proteins
sequence_length
537
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q13478}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 327..347; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins