CXCL2
entrez
2920
canonical
uniprot
P19875
canonical
ensembl
ENSG00000081041
resolver
ensp
ENSP00000427279
resolver
enst
ENST00000508487
resolver
genesymbol
CXCL2
resolver
genesymbol_syn
GRO2
resolver
genesymbol_syn
GROB
resolver
genesymbol_syn
MIP2A
resolver
genesymbol_syn
SCYB2
resolver
hgnc
HGNC:4603
resolver
uniprot
Q6FGD6
resolver
uniprot
Q9UPB8
resolver
uniprot_entry
CXCL2_HUMAN
resolver
uniprot_sec
Q6FGD6
resolver
uniprot_sec
Q9UPB8
resolver
amino_acid_sequence
MARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN
uniprot
proteins
function
FUNCTION: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. {ECO:0000269|PubMed:10725737}.
uniprot
proteins
mass_dalton
11389
uniprot
proteins
post_translational_modification
PTM: The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. {ECO:0000269|PubMed:10725737}.
uniprot
proteins
protein_family
Intercrine alpha (chemokine CxC) family
uniprot
proteins
pubmed
10600366
uniprot
proteins
pubmed
10725737
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2078213
uniprot
proteins
pubmed
2201751
uniprot
proteins
pubmed
2217207
uniprot
proteins
pubmed
2341726
uniprot
proteins
sequence_length
107
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins