Q8CEL2
uniprot
Q8CEL2
canonical
amino_acid_sequence
MSILTSPRGKVEVVHCRRTESQDIFCIKNLVRKFTQKLFGRLNIIYLLEKANLAVTVCNDKEEIMAHSIFLDYPNWNVAKQDNWIPLFRELDKEIPCTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVHICHRHNHYPQLHIRKARVEDHDDLMPIFMHYDNTLKEIYGEYFLAELIEAQDKDHHAVVCEVEGKAVGFMSVCTSVNLPLLHECFDLGPFHGFCTPHPDDILKPSREPSLEEGEEKHLKKCSTSLIIREMQIKTTLRFHLTPVRMAKIKNSETETSASCEEALPTVLGLVSEERLKQDMEKNLSILSLVDEEDVASSLSSSLLLSVESSHFRPLYLGDPIAFCIQLFCIDERYEARQVLISNVSLSLDFMSFVFSLFPGKNFCLISVPHLTPEFVLIQNFVKVVPFNNCTLDHDLYVFHRAGLLRSITIRLAKFLDTAGVEKLVSTLLLSTKILDDLAQYNEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDFIYFSHHQQEEHGRLNHFALNPIFRHYTKFFLKEILRLGYKSCLYYPVYPQTREGKLQSSYSHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKEVSKDQVSFALNHTNRKLTLEPKVTVNARIVVVGASSVGISFLETLVFCSHLKFNNLTLISTHGLPGKRLLHNEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTEQHLTNREVLELSKQRYTGTVPSNLFILNDEEDCVRMLCWLRNSSILTEGKVIVYGNTLDAYTTVETLLNIGMKGSGIYFVHPPTESNITCINNNDVESAVEDALSAAGVTVFHDALLAQWNHGQHPDPIYNACFTTSTKPIRLECSAFFSFYKKNVDYETFKAFNDACLVYDGRLVIDTTFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLSLFDPTLEPVTEPPADLDRLIPMYKGAKIQGGILPGSYHYLHISKPAIPTPLNLQRSQPDFGSDVVTGNAKKGTYFRLYINNYKLVEAITCFSKEPFPSSNYIRLFGQHEQVLNNLCTRFDDKLIPDLYSYFTEPWCMALFHDRFIDLKKELRQILISKQEEDKPTMEEIAYRLEEEEINLNEKPQKYLQRVFEDSIYKSLLEKSILDYLHYNQYHLPMYAWPGII
uniprot
proteins
function
FUNCTION: Involved in sperm flagellum assembly (PubMed:34792097, PubMed:35387802). Plays an essential role in the formation of the radial spokes in flagellum axoneme (PubMed:34792097, PubMed:35387802). {ECO:0000269|PubMed:34792097, ECO:0000269|PubMed:35387802}.
uniprot
proteins
mass_dalton
143289
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
34792097
uniprot
proteins
pubmed
35387802
uniprot
proteins
pubmed
37352829
uniprot
proteins
sequence_length
1252
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:34792097, ECO:0000269|PubMed:35387802}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q8NHU2}. Cell projection, cilium {ECO:0000250|UniProtKB:Q8NHU2}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:37352829}. Note=Localizes to the manchette in elongating spermatids in a CFAP70-dependent manner. {ECO:0000269|PubMed:37352829}.
uniprot
proteins