ECSCR
entrez
641700
canonical
uniprot
Q19T08
canonical
ensembl
ENSG00000249751
resolver
ensembl
ENSG00000279686
resolver
ensembl
ENSG00000288260
resolver
ensembl
ENSG00000288297
resolver
ensp
ENSP00000421364
resolver
ensp
ENSP00000479243
resolver
ensp
ENSP00000499933
resolver
ensp
ENSP00000500743
resolver
ensp
ENSP00000780593
resolver
enst
ENST00000515823
resolver
enst
ENST00000618155
resolver
enst
ENST00000673158
resolver
enst
ENST00000673382
resolver
genesymbol
ECSCR
resolver
genesymbol_syn
ECSM2
resolver
hgnc
HGNC:35454
resolver
uniprot
B4E3H7
resolver
uniprot
C3RSF2
resolver
uniprot_entry
ECSCR_HUMAN
resolver
uniprot_sec
B4E3H7
resolver
uniprot_sec
C3RSF2
resolver
amino_acid_sequence
MGTAGAMQLCWVILGFLLFRGHNSQPTMTQTSSSQGGLGGLSLTTEPVSSNPGYIPSSEANRPSHLSSTGTPGAGVPSSGRDGGTSRDTFQTVPPNSTTMSLSMREDATILPSPTSETVLTVAAFGVISFIVILVVVVIILVGVVSLRFKCRKSKESEDPQKPGSSGLSESCSTANGEKDSITLISMKNINMNNGKQSLSAEKVL
uniprot
proteins
function
FUNCTION: Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. {ECO:0000269|PubMed:18556573, ECO:0000269|PubMed:19416853}.
uniprot
proteins
mass_dalton
21295
uniprot
proteins
post_translational_modification
PTM: May be heavily O-glycosylated. {ECO:0000269|PubMed:18556573}.
uniprot
proteins
protein_family
ECSCR family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18556573
uniprot
proteins
pubmed
19416853
uniprot
proteins
sequence_length
205
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Cytoplasm.
uniprot
proteins
transmembrane_region
TRANSMEM 125..145; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins