ATP6V1C2
entrez
245973
canonical
uniprot
Q8NEY4
canonical
ensembl
ENSG00000143882
resolver
ensp
ENSP00000272238
resolver
ensp
ENSP00000371077
resolver
ensp
ENSP00000489280
resolver
ensp
ENSP00000497038
resolver
ensp
ENSP00000522171
resolver
ensp
ENSP00000591535
resolver
ensp
ENSP00000646755
resolver
enst
ENST00000635370
resolver
genesymbol
ATP6V1C2
resolver
hgnc
HGNC:18264
resolver
uniprot
A0A0U1RR16
resolver
uniprot
Q96EL8
resolver
uniprot_entry
A0A0U1RR16_HUMAN
resolver
uniprot_entry
VATC2_HUMAN
resolver
uniprot_sec
Q96EL8
resolver
amino_acid_sequence
MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVSVVDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEYLVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKAKENKFTVREFYYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLGNPDRPAAGQTDRERESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFHIDLSLLD
uniprot
proteins
function
FUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity). {ECO:0000250|UniProtKB:P21282, ECO:0000250|UniProtKB:P21283, ECO:0000250|UniProtKB:P31412}.
uniprot
proteins
mass_dalton
48759
uniprot
proteins
protein_family
V-ATPase C subunit family
uniprot
proteins
pubmed
12384298
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
sequence_length
427
uniprot
proteins