KCNJ9
entrez
3765
canonical
uniprot
Q92806
canonical
ensembl
ENSG00000162728
resolver
ensp
ENSP00000357067
resolver
ensp
ENSP00000534512
resolver
ensp
ENSP00000534513
resolver
ensp
ENSP00000534514
resolver
ensp
ENSP00000534515
resolver
ensp
ENSP00000534516
resolver
enst
ENST00000368088
resolver
enst
ENST00000864453
resolver
enst
ENST00000864454
resolver
enst
ENST00000864455
resolver
enst
ENST00000864456
resolver
enst
ENST00000864457
resolver
genesymbol
KCNJ9
resolver
genesymbol_syn
GIRK3
resolver
hgnc
HGNC:6270
resolver
uniprot
Q5JW75
resolver
uniprot_entry
KCNJ9_HUMAN
resolver
uniprot_sec
Q5JW75
resolver
amino_acid_sequence
MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGGEAGADKEQNGCLPPPESESKV
uniprot
proteins
function
FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium, This receptor is controlled by G proteins. Unable to produce channel activity when expressed alone (PubMed:10659995). Forms a functional channel in association with KCNJ3/GIRK1 (By similarity). {ECO:0000250|UniProtKB:Q63511, ECO:0000269|PubMed:10659995}.
uniprot
proteins
mass_dalton
44020
uniprot
proteins
protein_family
Inward rectifier-type potassium channel (TC 1.A.2.1) family
uniprot
proteins
protein_family
KCNJ9 subfamily
uniprot
proteins
pubmed
10659995
uniprot
proteins
pubmed
10913335
uniprot
proteins
pubmed
16710414
uniprot
proteins
sequence_length
393
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 58..82; /note="Helical; Name=M1"; /evidence="ECO:0000250"; TRANSMEM 135..156; /note="Helical; Name=M2"; /evidence="ECO:0000250
uniprot
proteins