Rab15
entrez
299156
canonical
uniprot
P35289
canonical
ensembl
ENSRNOG00000007364
resolver
ensembl
ENSRNOG00055020096
resolver
ensembl
ENSRNOG00060022440
resolver
ensembl
ENSRNOG00065017492
resolver
ensp
ENSRNOP00000010043
resolver
ensp
ENSRNOP00055027798
resolver
ensp
ENSRNOP00060032192
resolver
ensp
ENSRNOP00065023190
resolver
enst
ENSRNOT00000010043
resolver
enst
ENSRNOT00055034317
resolver
enst
ENSRNOT00060038942
resolver
enst
ENSRNOT00065029241
resolver
genesymbol
Rab15
resolver
uniprot
Q504L6
resolver
uniprot_entry
RAB15_RAT
resolver
uniprot_sec
Q504L6
resolver
activity_regulation
ACTIVITY REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. Regulated by GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity. Inhibited by GDP dissociation inhibitors (GDIs). {ECO:0000305}.
uniprot
proteins
amino_acid_sequence
MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELDGLRTCASNELALAELEEDEGKTEGPANSSKTCWC
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB15 may act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal (PubMed:1313420). {ECO:0000250|UniProtKB:P61026, ECO:0000269|PubMed:1313420}.
uniprot
proteins
mass_dalton
24283
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
1313420
uniprot
proteins
pubmed
1429617
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
212
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins