Trappc14
entrez
231807
canonical
uniprot
Q3UTZ3
canonical
ensembl
ENSMUSG00000036948
resolver
ensp
ENSMUSP00000046898
resolver
enst
ENSMUST00000048421
resolver
genesymbol
Trappc14
resolver
genesymbol_syn
Map11
resolver
uniprot
E9Q2V5
resolver
uniprot
Q8JZV2
resolver
uniprot_entry
TPC14_MOUSE
resolver
uniprot_sec
E9Q2V5
resolver
uniprot_sec
Q8JZV2
resolver
amino_acid_sequence
MESQCDYSMYFPAVPLPPRAELAGDPGRYRALPRRNHLYLGETVRFLLVLRCRGSVGAGVGGGAGLASRGAWTELATSLAALASVSAGGALPGCGSAGDQDADPPGGGDPGGGGLFRGCSPLLTHGQGPATSGGATTLPVEEPIVSTDEVIFPLTVSLDRLPPGTPKAKIVVTVWKREVEAPEVRDQGYLRLLQTRSPGETFRGEQSAFKAQVSTLLTLLPPPVLKCRQFTVAGKHLTVLKVLNSSSQEEISIWDIRILPNFNASYLPVMPDGSVLLVDNVCHQSGEVSMGSFCRLPGTSGYFPCPLSALEEHNFLFQLRGGEQPPPGAKEGLEVPLIAVVQWSTPKLPFTQSIYTHYRLPSVRLDRPCFVMTASCESPVRTYERFTVTYTLLNNLQDFLAVRLVWTPEHAQAGKQLCEEERRAMQAALDSIVCHTPLNNLGFSRKGSALTFSVAFQALRTGLFELSQHMKLKLQFTASVSHPPPEARPLSRKSSPSSPAVRDLVERHQASLGRSQSFSHQQPSRSHLMRSGSVMERRAITPPVASPVGRPLYLPPDKAVLSLDKIAKRECKVLVVEPVK
uniprot
proteins
function
FUNCTION: Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether. TRAPPC14 is dispensable for TRAPPII complex integrity but mediates RAB3IP preciliary vesicle trafficking to the mother centriole during ciliogenesis. Modulates YAP1 activity as transcriptional regulator. {ECO:0000250|UniProtKB:Q8WVR3}.
uniprot
proteins
mass_dalton
62750
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
580
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q8WVR3}. Vesicle {ECO:0000250|UniProtKB:Q8WVR3}. Midbody {ECO:0000250|UniProtKB:Q8WVR3}. Note=During mitosis, precedes alpha-tubulin in gap formation of cell abscission at the midbody and is co-localized with PLK1 at the edges of microtubules extensions of daughter cells post cytokinesis abscission. Colocalizes with RAB3IP on preciliary vesicles. {ECO:0000250|UniProtKB:Q8WVR3}.
uniprot
proteins