Arhgap45
entrez
70719
canonical
uniprot
Q3TBD2
canonical
ensembl
ENSMUSG00000035697
resolver
ensp
ENSMUSP00000041019
resolver
ensp
ENSMUSP00000097100
resolver
ensp
ENSMUSP00000101012
resolver
enst
ENSMUST00000099501
resolver
enst
ENSMUST00000105373
resolver
genesymbol
Arhgap45
resolver
genesymbol_syn
Hmha1
resolver
uniprot
D3Z7R7
resolver
uniprot
G3X9Q3
resolver
uniprot
Q3TDD2
resolver
uniprot
Q3TSW0
resolver
uniprot
Q3TXM6
resolver
uniprot
Q3UZ72
resolver
uniprot
Q8BI83
resolver
uniprot
Q9CU46
resolver
uniprot_entry
D3Z7R7_MOUSE
resolver
uniprot_entry
G3X9Q3_MOUSE
resolver
uniprot_entry
HMHA1_MOUSE
resolver
uniprot_sec
Q3TDD2
resolver
uniprot_sec
Q3TSW0
resolver
uniprot_sec
Q3TXM6
resolver
uniprot_sec
Q3UZ72
resolver
uniprot_sec
Q8BI83
resolver
uniprot_sec
Q9CU46
resolver
amino_acid_sequence
MFSRKKRELMKTPSISKKNRAGSPNPQSSSGELPRKDWTEAPGLEPPATSLSTVAKGTGTLKRPTSLSRHASAAGFPLSGTATWTLVRGYRSPLSAASPAELPTEGAFPDGVEDISTLLADVARFAEGLEKLKECVLQDDLLEARRPLAHECLGEALRVMRQVISRYPLLNTVETLTAAGTLIAKVKAFHYECNNESDKREFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQSMENLYGAGTEGPPHNVEECEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLISYLEKRTTLEMEFAKGLQKVVHNCRQSVTHEPHMPLLSIYSLALEQDLEFGHGMVQAAGTLQTQTFMQPLTLRRLEHERRRKEIKESWHRAQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSNNSWSPIMRTRKGSFNPGDASGPEAAGSPPEEGGTSEAAPNKDHRGGRGHQVHKSWPISISDTEVGLDTSSGDLKKFDRTSSSGTMSSSEELGDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAALSTPDGVPFIVKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGRQGGSESEAATLAMVGRLRELMQDLPAENRATLLYLLKHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRPTDATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEEAPGSQEGASTQCGQLESAEGIVFPLQEEAEDGSRESHAASNDSDSELEDASDPLSSSDASALHRLSFLEQTEAGLEEGPQSHSGSEEQLEGEDGAPGPWLCHFNTNQSNNTSRAPLPTMRLRGGQITGGTSQERQPQFV
uniprot
proteins
function
FUNCTION: Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity. {ECO:0000250|UniProtKB:Q92619}.
uniprot
proteins
mass_dalton
122902
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16774541
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1116
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q92619}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:Q92619}.
uniprot
proteins