Khdrbs2
entrez
170843
canonical
uniprot
Q920F3
canonical
ensembl
ENSRNOG00000012284
resolver
ensembl
ENSRNOG00055001621
resolver
ensembl
ENSRNOG00060026440
resolver
ensembl
ENSRNOG00065011326
resolver
ensp
ENSRNOP00000016579
resolver
ensp
ENSRNOP00000100781
resolver
ensp
ENSRNOP00055001946
resolver
ensp
ENSRNOP00060038027
resolver
ensp
ENSRNOP00065014051
resolver
enst
ENSRNOT00000016578
resolver
enst
ENSRNOT00000154861
resolver
enst
ENSRNOT00055002613
resolver
enst
ENSRNOT00060045828
resolver
enst
ENSRNOT00065018382
resolver
genesymbol
Khdrbs2
resolver
genesymbol_syn
Slm1
resolver
uniprot
A0ABK0L7C9
resolver
uniprot_entry
A0ABK0L7C9_RAT
resolver
uniprot_entry
KHDR2_RAT
resolver
amino_acid_sequence
MGEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGRKEDEEKKYLDVISNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSEESGRGRGIRGRGIRITPTAPSRGRGGAVPPPPPPGRGVLTPRGTTVTRGALPVPPVARGVPTPRARGTAAVPGYRAPPPPAPEAYEEYGYDDGYGGEYDDQTYEAYDNSYVTPTQSVPEYYDYGHGVNEDAYDSYAPEEWTTTRSSLKAPPPRSARGGYREHPYGRY
uniprot
proteins
function
FUNCTION: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis (By similarity). Binds both poly(A) and poly(U) homopolymers (By similarity). Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). {ECO:0000250, ECO:0000269|PubMed:15345239}.
uniprot
proteins
mass_dalton
38854
uniprot
proteins
post_translational_modification
PTM: Methylated. {ECO:0000250|UniProtKB:Q5VWX1}.; PTM: Phosphorylated on tyrosine residues by FYN. Tyrosine phosphorylated by PTK6 and SRC (By similarity). Tyrosine phosphorylated by SRC during mitosis (By similarity). {ECO:0000250|UniProtKB:Q9WU01}.
uniprot
proteins
protein_family
KHDRBS family
uniprot
proteins
pubmed
15345239
uniprot
proteins
pubmed
19282290
uniprot
proteins
sequence_length
349
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9WU01}.
uniprot
proteins