Q3U3S3
uniprot
Q3U3S3
canonical
amino_acid_sequence
MDSCDFRGLTSRRRTSNLKNYFVGATPLQKRLELVRRQNSDFPSPSRRKIPQCSQLQEDIDPQKVAFLLHKQWTIYSLTPLYKFSYSNLKDYSRLLSAFIVAEKQKGVAVEVGEDFNIKVIFSTLLGVKGTQRDHEAFLVQILSKSQSSREHREDKVLWTGWFCCVFGESLQETVSEDFTCLPLFLANGAESNTSLIRDWFQKTFDCCFSPLAISAFNLSWMAAMWTACKMDRYMATTEFLWSVPCSPQSLDISYAIHPEDAKALWESVHKTPGEVTQEEVDLFMNCLYSHFHRHFKIHLAATRLVRVSTSVASAHTDGKIKVSLNRSN
uniprot
proteins
function
FUNCTION: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37725
uniprot
proteins
protein_family
CENP-L/IML3 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
329
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome, centromere {ECO:0000250}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex (By similarity). {ECO:0000250}.
uniprot
proteins