Pts
entrez
19286
canonical
uniprot
Q9R1Z7
canonical
ensembl
ENSMUSG00000032067
resolver
ensp
ENSMUSP00000034570
resolver
ensp
ENSMUSP00000149552
resolver
ensp
ENSMUSP00000150693
resolver
ensp
ENSMUSP00000291848
resolver
ensp
ENSMUSP00000291863
resolver
enst
ENSMUST00000034570
resolver
enst
ENSMUST00000214873
resolver
enst
ENSMUST00000215416
resolver
genesymbol
Pts
resolver
uniprot
A0A1L1SRN0
resolver
uniprot
Q3UIB6
resolver
uniprot
Q9Z2N2
resolver
uniprot_entry
A0A1L1SRN0_MOUSE
resolver
uniprot_entry
PTPS_MOUSE
resolver
uniprot_sec
Q3UIB6
resolver
uniprot_sec
Q9Z2N2
resolver
amino_acid_sequence
MSAAGDLRRRARLSRLVSFSASHRLHSPSLSDEENLRVFGKCNNPNGHGHNYKVVVTVHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADAVSTTENVAVYIWESLQKLLPVGALYKVKVFETDNNIVVYKGE
uniprot
proteins
ec_number
4.2.3.12
uniprot
proteins
function
FUNCTION: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. {ECO:0000305|PubMed:9894812}.
uniprot
proteins
mass_dalton
16188
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Ser-18 is required for maximal enzyme activity. {ECO:0000250}.
uniprot
proteins
protein_family
PTPS family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9894812
uniprot
proteins
sequence_length
144
uniprot
proteins