PI3
entrez
5266
canonical
uniprot
P19957
canonical
ensembl
ENSG00000124102
resolver
ensp
ENSP00000243924
resolver
ensp
ENSP00000641389
resolver
enst
ENST00000243924
resolver
enst
ENST00000971330
resolver
genesymbol
PI3
resolver
genesymbol_syn
WAP3
resolver
genesymbol_syn
WFDC14
resolver
hgnc
HGNC:8947
resolver
uniprot
E1P618
resolver
uniprot
Q6FG74
resolver
uniprot_entry
ELAF_HUMAN
resolver
uniprot_sec
E1P618
resolver
uniprot_sec
Q6FG74
resolver
amino_acid_sequence
MRASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVKAQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ
uniprot
proteins
function
FUNCTION: Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Has been shown to inhibit the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor and to produce a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1 (TRPV1) (PubMed:29483648). {ECO:0000269|PubMed:29483648}.
uniprot
proteins
mass_dalton
12270
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
1339270
uniprot
proteins
pubmed
1536690
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2001428
uniprot
proteins
pubmed
2039600
uniprot
proteins
pubmed
2394696
uniprot
proteins
pubmed
29483648
uniprot
proteins
pubmed
7685029
uniprot
proteins
pubmed
8476637
uniprot
proteins
pubmed
8794736
uniprot
proteins
pubmed
9171290
uniprot
proteins
sequence_length
117
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins