LSM14B
entrez
149986
canonical
uniprot
Q9BX40
canonical
ensembl
ENSG00000149657
resolver
ensp
ENSP00000279068
resolver
ensp
ENSP00000355209
resolver
ensp
ENSP00000556917
resolver
ensp
ENSP00000594465
resolver
genesymbol
LSM14B
resolver
genesymbol_syn
C20orf40
resolver
genesymbol_syn
FAM61B
resolver
genesymbol_syn
RAP55B
resolver
hgnc
HGNC:15887
resolver
uniprot
Q6PFW8
resolver
uniprot
Q96LH8
resolver
uniprot_entry
LS14B_HUMAN
resolver
uniprot_sec
Q6PFW8
resolver
uniprot_sec
Q96LH8
resolver
amino_acid_sequence
MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMAPYGPLAASSLLSQQYAASLGLGAGFPSIPVGKSPMVEQAVQTGSADNLNAKKLLPGKGTTGTQLNGRQAQPSSKTASDVVQPAAVQAQGQVNDENRRPQRRRSGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDLAVVTQSAEAPAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNPTSHRAGTGRV
uniprot
proteins
function
FUNCTION: mRNA-binding protein essential for female fertility, oocyte meiotic maturation and the assembly of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes. Ensures the proper accumulation and clearance of mRNAs essential for oocyte meiotic maturation and the normal progression from Meiosis I to Meiosis II in oocytes. Promotes the translation of some oogenesis-related mRNAs. Regulates the expression and/or localization of some key P-body proteins in oocytes. Essential for the assembly of the primordial follicle in the ovary. {ECO:0000250|UniProtKB:Q8CGC4}.
uniprot
proteins
mass_dalton
42071
uniprot
proteins
protein_family
LSM14 family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18723115
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
31422817
uniprot
proteins
sequence_length
385
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, Cytoplasmic ribonucleoprotein granule {ECO:0000250|UniProtKB:Q8CGC4}. Note=Localizes to MARDO (mitochondria-associated ribonucleoprotein domain), a mitochondria-associated membraneless compartment that stores mRNAs in oocytes. {ECO:0000250|UniProtKB:Q8CGC4}.
uniprot
proteins