ARL4A
entrez
10124
canonical
uniprot
P40617
canonical
ensembl
ENSG00000122644
resolver
ensp
ENSP00000349250
resolver
ensp
ENSP00000379897
resolver
ensp
ENSP00000379898
resolver
ensp
ENSP00000379899
resolver
ensp
ENSP00000385236
resolver
ensp
ENSP00000498350
resolver
ensp
ENSP00000561965
resolver
ensp
ENSP00000601826
resolver
ensp
ENSP00000601827
resolver
ensp
ENSP00000601828
resolver
ensp
ENSP00000601829
resolver
enst
ENST00000356797
resolver
enst
ENST00000396662
resolver
enst
ENST00000396663
resolver
enst
ENST00000396664
resolver
enst
ENST00000404894
resolver
enst
ENST00000651779
resolver
enst
ENST00000891906
resolver
enst
ENST00000931767
resolver
enst
ENST00000931768
resolver
enst
ENST00000931769
resolver
enst
ENST00000931770
resolver
genesymbol
ARL4A
resolver
genesymbol_syn
ARL4
resolver
hgnc
HGNC:695
resolver
uniprot
A4D119
resolver
uniprot
P80418
resolver
uniprot
Q49AF5
resolver
uniprot_entry
ARL4A_HUMAN
resolver
uniprot_sec
A4D119
resolver
uniprot_sec
P80418
resolver
uniprot_sec
Q49AF5
resolver
amino_acid_sequence
MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLEKLHDMIIKRRKMLRQQKKKR
uniprot
proteins
function
FUNCTION: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. {ECO:0000269|PubMed:10980193, ECO:0000269|PubMed:17398095}.
uniprot
proteins
mass_dalton
22615
uniprot
proteins
mutagenesis
MUTAGEN 34; /note="T->N: Inhibits relocalization of CYTH2 to the plasma membrane. Strongly localized in the nucleolus."; /evidence="ECO:0000269|PubMed:10980193, ECO:0000269|PubMed:17398095"; MUTAGEN 79; /note="Q->L: Localized in the nucleus and nucleolus."; /evidence="ECO:0000269|PubMed:10980193, ECO:0000269|PubMed:17398095
uniprot
proteins
post_translational_modification
PTM: Myristoylated. {ECO:0000269|PubMed:10980193}.
uniprot
proteins
protein_family
Arf family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
10462049
uniprot
proteins
pubmed
10831612
uniprot
proteins
pubmed
10980193
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17398095
uniprot
proteins
sequence_length
200
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is dependent by nucleotide binding.
uniprot
proteins