Pdgfb
entrez
24628
canonical
uniprot
Q05028
canonical
ensembl
ENSRNOG00000017197
resolver
ensp
ENSRNOP00000023196
resolver
genesymbol
Pdgfb
resolver
uniprot
A0A221LG85
resolver
uniprot_entry
A0A221LG85_RAT
resolver
uniprot_entry
PDGFB_RAT
resolver
amino_acid_sequence
LPLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHRDSVDEDGAELDLNMTRAHSGVESESSSRGRRSLGSLAAAEPAVIAECKTRTEVFQISRNLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRASQVQMRPVQVRKIEIVRKKPVFKKATVTLEDHLACKCETVVTPRPVTRSPGTSREHRAKTPQTRVTVRTVRIRRPPKGKHRKFKHTHDKK
uniprot
proteins
function
FUNCTION: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity). {ECO:0000250|UniProtKB:P01127, ECO:0000250|UniProtKB:P31240}.
uniprot
proteins
mass_dalton
25603
uniprot
proteins
protein_family
PDGF/VEGF growth factor family
uniprot
proteins
pubmed
7758166
uniprot
proteins
pubmed
8318539
uniprot
proteins
sequence_length
225
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Note=Released by platelets upon wounding. {ECO:0000250}.
uniprot
proteins