HSF2
entrez
3298
canonical
uniprot
Q03933
canonical
ensembl
ENSG00000025156
resolver
ensp
ENSP00000357440
resolver
ensp
ENSP00000400380
resolver
ensp
ENSP00000778953
resolver
genesymbol
HSF2
resolver
genesymbol_syn
HSTF2
resolver
hgnc
HGNC:5225
resolver
uniprot
B4DGJ4
resolver
uniprot
Q0VAH9
resolver
uniprot
Q2M1K4
resolver
uniprot
Q9BS48
resolver
uniprot
Q9H445
resolver
uniprot_entry
HSF2_HUMAN
resolver
uniprot_entry
Q9BS48_HUMAN
resolver
uniprot_sec
B4DGJ4
resolver
uniprot_sec
Q0VAH9
resolver
uniprot_sec
Q2M1K4
resolver
uniprot_sec
Q9H445
resolver
amino_acid_sequence
MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQSGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
uniprot
proteins
function
FUNCTION: DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
uniprot
proteins
mass_dalton
60348
uniprot
proteins
mutagenesis
MUTAGEN 109; /note="R->G: Fails to translocate to nucleus."; /evidence="ECO:0000269|PubMed:8339932"; MUTAGEN 196..198; /note="RKR->ASS: Fails to translocate to nucleus."; /evidence="ECO:0000269|PubMed:8339932
uniprot
proteins
protein_family
HSF family
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1871106
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
25772364
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
8339932
uniprot
proteins
sequence_length
536
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:8339932}. Nucleus {ECO:0000269|PubMed:8339932}. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation.
uniprot
proteins