Fmnl3
entrez
22379
canonical
uniprot
Q6ZPF4
canonical
ensembl
ENSMUSG00000023008
resolver
ensp
ENSMUSP00000079984
resolver
ensp
ENSMUSP00000085566
resolver
ensp
ENSMUSP00000113094
resolver
ensp
ENSMUSP00000281910
resolver
enst
ENSMUST00000120633
resolver
genesymbol
Fmnl3
resolver
genesymbol_syn
Frl2
resolver
genesymbol_syn
Kiaa2014
resolver
uniprot
D3Z7A7
resolver
uniprot
Q3TCF9
resolver
uniprot
Q3U2E4
resolver
uniprot_entry
D3Z7A7_MOUSE
resolver
uniprot_entry
FMNL3_MOUSE
resolver
uniprot_sec
Q3TCF9
resolver
uniprot_sec
Q3U2E4
resolver
amino_acid_sequence
MGNLESTDGGPGEPPSVPLLLPPGKTPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPNVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPNALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVHTLRRLIKEKEEAFQRRCHLEPSARGLESMGGEALARVGPTELTEGIPPSDLDLLAPAPPTEETLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQINGTVFSELDDEKILEDLDLDRFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHHDESNC
uniprot
proteins
function
FUNCTION: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis. In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignment. {ECO:0000250|UniProtKB:Q6NXC0, ECO:0000250|UniProtKB:Q8IVF7}.
uniprot
proteins
mass_dalton
117169
uniprot
proteins
protein_family
Formin homology family
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21148482
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1028
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8IVF7}. Cell membrane {ECO:0000250|UniProtKB:Q8IVF7}; Lipid-anchor {ECO:0000255}. Note=Enriched in lamellipodia. {ECO:0000250|UniProtKB:Q8IVF7}.
uniprot
proteins