Katnal1
entrez
288449
canonical
uniprot
Q5XIK7
canonical
ensembl
ENSRNOG00000047618
resolver
ensembl
ENSRNOG00055003830
resolver
ensembl
ENSRNOG00060001909
resolver
ensembl
ENSRNOG00065006498
resolver
ensp
ENSRNOP00000068753
resolver
ensp
ENSRNOP00055004567
resolver
ensp
ENSRNOP00060001947
resolver
ensp
ENSRNOP00065007298
resolver
enst
ENSRNOT00000077328
resolver
enst
ENSRNOT00055006045
resolver
enst
ENSRNOT00060002958
resolver
enst
ENSRNOT00065010023
resolver
genesymbol
Katnal1
resolver
uniprot_entry
KATL1_RAT
resolver
amino_acid_sequence
MNLAEICENAKKGREYALLGNYDSSMVYYQGVIQQIQRHCQSLRDPATKAKWQQVRQELLEEYEQVKSIVSTLESFKMDKPPDFPVSCRDEPFRDPAVWPPPVPAEHRAPPQIRRPNREVRPLRKDMGAGARGLVGRAHQISKSDKAASRDKDYRARGRDDKARKNMQDGASDGEIPKFDGAGYDKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKISLREVELDPDIHLEDIAEKTEGYSGADITNICRDASLMAMRRRINGLSPEEIRALSKEELQMPVTRGDLELALKKIAKSVSAADLEKYEKWMVEFGSA
uniprot
proteins
ec_number
5.6.1.1
uniprot
proteins
function
FUNCTION: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro (By similarity). {ECO:0000250|UniProtKB:Q8K0T4, ECO:0000250|UniProtKB:Q9BW62}.
uniprot
proteins
mass_dalton
55201
uniprot
proteins
protein_family
A-like 1 sub-subfamily
uniprot
proteins
protein_family
AAA ATPase family
uniprot
proteins
protein_family
Katanin p60 subunit A1 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
488
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000255|HAMAP-Rule:MF_03024}. Cytoplasm {ECO:0000250|UniProtKB:Q9BW62}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q9BW62}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9BW62}. Note=Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (By similarity). {ECO:0000250|UniProtKB:Q8K0T4, ECO:0000250|UniProtKB:Q9BW62}.
uniprot
proteins