Iqce
entrez
74239
canonical
uniprot
Q6PCQ0
canonical
ensembl
ENSMUSG00000036555
resolver
ensp
ENSMUSP00000045913
resolver
ensp
ENSMUSP00000077050
resolver
ensp
ENSMUSP00000228328
resolver
ensp
ENSMUSP00000228329
resolver
ensp
ENSMUSP00000228332
resolver
ensp
ENSMUSP00000228334
resolver
ensp
ENSMUSP00000228335
resolver
ensp
ENSMUSP00000228336
resolver
ensp
ENSMUSP00000228337
resolver
ensp
ENSMUSP00000228343
resolver
genesymbol
Iqce
resolver
uniprot
Q8CDZ1
resolver
uniprot
Q9D9U3
resolver
uniprot_entry
IQCE_MOUSE
resolver
uniprot_sec
Q8CDZ1
resolver
uniprot_sec
Q9D9U3
resolver
amino_acid_sequence
MSLGTTDIASETGDDSLSAITFESDIESKTKRKSFHKPPSTSPKSPYYSKPRKVTSWRSLKTAGSMPLSSRMSLTPQKLWLGSSKQGSVAQPPSPTLTSEHAWTHPPSCTPDYLTEAVRAKRADLRRSGSHGHVSGTSVYREKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPSRGPDFVRTLAEKKPDTGWVITGLKQRIFRLEQQCKEKDNTINKLQTDMKTTNLEEMRIAMETYYEEIHRLQTLLASSEATGKKPMVEKKLGVKRQKKMSSALLNLTRSVQELTEENQSLKEDLDRMLSNSPTISKIKGYGDWSKPRLLRRIAELEKKVSSSESPKQSTSELVNPNPLVRSPSNISVQKQPKGDQSPEDLPKVAPCEEQEHLQGTVKSLREELGALQEQLLEKDLEMKQLLQSKIDLEKELETAREGEKGRQEQEQALREEVEALTKKCQELEEAKREEKNSFVAVTHEAHPELHAPSPCSRHSEPDSDNSAGEEGSSQPPAPCSEERREAAIRTLQAQWKAHRRKKREAALDEAATVLQAAFRGHLARSKLVRSKVPDSRSPSLPGLLSPLNQSSPAPRVLSPISPAEENPTQEEAVIVIQSILRGYLAQARFIASCCREIAASSQRETVSLTPSGSASPPSLRASPGVIRKELCASEELRETSASEPAPSVPYSAQGGHGDCPSSSSLEAVPSMKDAMCEERSSSPRSAGPSLAEPSPPELQPLSPPPVEDICSDDSDDIIFSPFLPRKKSPSPF
uniprot
proteins
function
FUNCTION: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (PubMed:24582806). Required for proper limb morphogenesis (By similarity). {ECO:0000250|UniProtKB:Q6IPM2, ECO:0000269|PubMed:24582806}.
uniprot
proteins
mass_dalton
86356
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24582806
uniprot
proteins
sequence_length
778
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium membrane {ECO:0000269|PubMed:24582806}; Peripheral membrane protein {ECO:0000269|PubMed:24582806}; Cytoplasmic side {ECO:0000269|PubMed:24582806}. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner (PubMed:24582806). {ECO:0000269|PubMed:24582806}.
uniprot
proteins