Slc2a3
entrez
25551
canonical
uniprot
Q07647
canonical
ensembl
ENSRNOG00000008376
resolver
ensp
ENSRNOP00000066684
resolver
enst
ENSRNOT00000071745
resolver
genesymbol
Slc2a3
resolver
genesymbol_syn
Glut3
resolver
uniprot
A0A0G2JT05
resolver
uniprot
Q62729
resolver
uniprot_entry
A0A0G2JT05_RAT
resolver
uniprot_entry
GTR3_RAT
resolver
uniprot_sec
Q62729
resolver
activity_regulation
ACTIVITY REGULATION: Deoxyglucose transport is inhibited by D-glucose, D-galactose and maltose. Galactose transport is inhibited by D-glucose and maltose. {ECO:0000250|UniProtKB:P11169}.
uniprot
proteins
amino_acid_sequence
MGTAKVTPSLVFAVTVATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPREGLLTTLWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINRKEEDQATEILQRLWGTPDVIQEIQEMKDESIRMSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDEYEAMSFVCIVAILVYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVFFLIFTSFKVPETKGRTFEDITRAFEGQAHSGKGSAGVELNSMQPVKETPGNA
uniprot
proteins
function
FUNCTION: Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Required for mesendoderm differentiation (By similarity). {ECO:0000250|UniProtKB:P11169, ECO:0000250|UniProtKB:P32037}.
uniprot
proteins
mass_dalton
53581
uniprot
proteins
protein_family
Glucose transporter subfamily
uniprot
proteins
protein_family
Major facilitator superfamily
uniprot
proteins
protein_family
Sugar transporter (TC 2.A.1.1) family
uniprot
proteins
pubmed
21076856
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
24995978
uniprot
proteins
pubmed
7475896
uniprot
proteins
pubmed
8243635
uniprot
proteins
sequence_length
493
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P11169}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P11169}. Perikaryon {ECO:0000269|PubMed:24995978}. Cell projection {ECO:0000269|PubMed:24995978}. Note=Localized to densely spaced patches along neuronal processes. {ECO:0000269|PubMed:24995978}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..32; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 65..85; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 91..111; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 119..142; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 154..174; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 184..204; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 270..290; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 305..325; /note="Helical; Name=8"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 332..352; /note="Helical; Name=9"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 364..389; /note="Helical; Name=10"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 400..420; /note="Helical; Name=11"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255"; TRANSMEM 430..450; /note="Helical; Name=12"; /evidence="ECO:0000250|UniProtKB:P11169, ECO:0000255
uniprot
proteins