PROCR
entrez
10544
canonical
uniprot
Q9UNN8
canonical
ensembl
ENSG00000101000
resolver
ensp
ENSP00000216968
resolver
ensp
ENSP00000522863
resolver
ensp
ENSP00000522864
resolver
enst
ENST00000216968
resolver
enst
ENST00000852804
resolver
enst
ENST00000852805
resolver
genesymbol
PROCR
resolver
genesymbol_syn
EPCR
resolver
hgnc
HGNC:9452
resolver
uniprot
B2RC04
resolver
uniprot
Q14218
resolver
uniprot
Q6IB56
resolver
uniprot
Q96CB3
resolver
uniprot
Q9ULX1
resolver
uniprot_entry
EPCR_HUMAN
resolver
uniprot_sec
B2RC04
resolver
uniprot_sec
Q14218
resolver
uniprot_sec
Q6IB56
resolver
uniprot_sec
Q96CB3
resolver
uniprot_sec
Q9ULX1
resolver
amino_acid_sequence
MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTGGRRC
uniprot
proteins
function
FUNCTION: Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
uniprot
proteins
mass_dalton
26671
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:12034704}.; PTM: A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
uniprot
proteins
pubmed
10397730
uniprot
proteins
pubmed
10570964
uniprot
proteins
pubmed
10681599
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12034704
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
7929370
uniprot
proteins
sequence_length
238
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 211..231; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins