PLAAT5
entrez
117245
canonical
uniprot
Q96KN8
canonical
ensembl
ENSG00000168004
resolver
ensp
ENSP00000301790
resolver
ensp
ENSP00000443873
resolver
ensp
ENSP00000444809
resolver
ensp
ENSP00000576992
resolver
ensp
ENSP00000576993
resolver
ensp
ENSP00000734737
resolver
genesymbol
HRASLS5
resolver
genesymbol
PLAAT5
resolver
genesymbol_syn
HRASLS5
resolver
genesymbol_syn
HRLP5
resolver
hgnc
HGNC:24978
resolver
uniprot
B4DY88
resolver
uniprot
B7X6T1
resolver
uniprot
F5GZ87
resolver
uniprot
F5H4Y9
resolver
uniprot
Q8NE88
resolver
uniprot_entry
B4DY88_HUMAN
resolver
uniprot_entry
PLAT5_HUMAN
resolver
uniprot_entry
Q8NE88_HUMAN
resolver
uniprot_sec
B7X6T1
resolver
uniprot_sec
F5GZ87
resolver
uniprot_sec
F5H4Y9
resolver
amino_acid_sequence
MGLSPGAEGEYALRLPRIPPPLPKPASRTASTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALMEGAKAAGAVISAVVDSIKPKPITA
uniprot
proteins
ec_number
2.3.1.-
uniprot
proteins
ec_number
3.1.1.32
uniprot
proteins
ec_number
3.1.1.4
uniprot
proteins
function
FUNCTION: Exhibits both phospholipase A1/2 and acyltransferase activities (PubMed:22825852, PubMed:26503625). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (PubMed:22825852). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs) (PubMed:19000777, PubMed:22825852). {ECO:0000269|PubMed:19000777, ECO:0000269|PubMed:22825852, ECO:0000303|PubMed:26503625}.
uniprot
proteins
mass_dalton
30312
uniprot
proteins
protein_family
H-rev107 family
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
19000777
uniprot
proteins
pubmed
22825852
uniprot
proteins
pubmed
26503625
uniprot
proteins
sequence_length
279
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q4KLN5}.
uniprot
proteins