Ptp4a1
entrez
19243
canonical
uniprot
Q63739
canonical
ensembl
ENSMUSG00000026064
resolver
ensembl
ENSMUSG00000117310
resolver
ensembl
ENSMUSG00000144322
resolver
ensp
ENSMUSP00000027232
resolver
ensp
ENSMUSP00000156862
resolver
ensp
ENSMUSP00000262769
resolver
ensp
ENSMUSP00000262779
resolver
enst
ENSMUST00000027232
resolver
enst
ENSMUST00000232841
resolver
genesymbol
Ptp4a1
resolver
genesymbol_syn
Prl1
resolver
uniprot
B9EKL6
resolver
uniprot
O09097
resolver
uniprot
O09154
resolver
uniprot
Q3UFU9
resolver
uniprot_entry
B9EKL6_MOUSE
resolver
uniprot_entry
TP4A1_MOUSE
resolver
uniprot_sec
O09097
resolver
uniprot_sec
O09154
resolver
uniprot_sec
Q3UFU9
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by sodium orthovanadate and pentamidine. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
19815
uniprot
proteins
mutagenesis
MUTAGEN 104; /note="C->S: Abolishes activity."; /evidence="ECO:0000269|PubMed:11278933
uniprot
proteins
post_translational_modification
PTM: Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus.
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
10194868
uniprot
proteins
pubmed
10747914
uniprot
proteins
pubmed
11278933
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
173
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10747914}; Lipid-anchor {ECO:0000269|PubMed:10747914}. Early endosome {ECO:0000269|PubMed:10747914}. Endoplasmic reticulum {ECO:0000269|PubMed:10747914}. Cytoplasm {ECO:0000269|PubMed:10747914}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:10747914}. Nucleus {ECO:0000250|UniProtKB:Q78EG7}. Note=And mitotic spindle.
uniprot
proteins