STK16
entrez
8576
canonical
uniprot
O75716
canonical
ensembl
ENSG00000115661
resolver
ensp
ENSP00000379964
resolver
ensp
ENSP00000386309
resolver
ensp
ENSP00000386553
resolver
ensp
ENSP00000386928
resolver
ensp
ENSP00000545321
resolver
ensp
ENSP00000583799
resolver
enst
ENST00000396738
resolver
enst
ENST00000409516
resolver
enst
ENST00000409638
resolver
enst
ENST00000409743
resolver
enst
ENST00000875262
resolver
enst
ENST00000913740
resolver
genesymbol
STK16
resolver
genesymbol_syn
MPSK1
resolver
genesymbol_syn
PKL12
resolver
genesymbol_syn
TSF1
resolver
hgnc
HGNC:11394
resolver
uniprot
A0ACI8SNJ0
resolver
uniprot
A8K9H9
resolver
uniprot
B4DPS1
resolver
uniprot
B8ZZI5
resolver
uniprot
Q5U0F8
resolver
uniprot
Q96KI2
resolver
uniprot
Q9BUH4
resolver
uniprot
Q9UEN3
resolver
uniprot
Q9UP78
resolver
uniprot_entry
A0ACI8SNJ0_HUMAN
resolver
uniprot_entry
B4DPS1_HUMAN
resolver
uniprot_entry
B8ZZI5_HUMAN
resolver
uniprot_entry
STK16_HUMAN
resolver
uniprot_sec
A8K9H9
resolver
uniprot_sec
Q5U0F8
resolver
uniprot_sec
Q96KI2
resolver
uniprot_sec
Q9BUH4
resolver
uniprot_sec
Q9UEN3
resolver
uniprot_sec
Q9UP78
resolver
amino_acid_sequence
MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQHTTQI
uniprot
proteins
ec_number
2.7.10.2
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins. {ECO:0000269|PubMed:10364453}.
uniprot
proteins
mass_dalton
34656
uniprot
proteins
mutagenesis
MUTAGEN 2; /note="G->A: Loss of myristoylation."; /evidence="ECO:0000269|PubMed:10364453"; MUTAGEN 6; /note="C->S: Loss of palmitoylation."; /evidence="ECO:0000269|PubMed:10364453"; MUTAGEN 8; /note="C->S: Loss of palmitoylation."; /evidence="ECO:0000269|PubMed:10364453
uniprot
proteins
post_translational_modification
PTM: Mainly autophosphorylated on serine/threonine residues. Also autophosphorylated on Tyr-198. {ECO:0000269|PubMed:18184589}.; PTM: It is uncertain whether palmitoylation is on Cys-6 and/or Cys-8. {ECO:0000269|PubMed:10364453}.
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
10364453
uniprot
proteins
pubmed
10947953
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
18184589
uniprot
proteins
pubmed
9712705
uniprot
proteins
sequence_length
305
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region. Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Associates with Golgi and Golgi-derived vesicles. {ECO:0000250}.
uniprot
proteins