F1LM81
uniprot
F1LM81
canonical
amino_acid_sequence
MAFGKSHRDPYATSLGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLSLSLIDMCMQNCGPSFQSLIVKKEFVKDTLVKLLNPRYTLPLETQNRILSFIKMWSQGFPGGVDVSEVKEVYLDLLKKGVQFPPLDGEPETKQEAGQISPSRPTSVPTAPALSSIIAPKNPTISLVPEQIGKLHSELDMVKMNVKVMTAILMENTPGSENHEDIELLRKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRLLEQKRNPTEANQTSSEPSAPSCDLLNLGPVAPVPVSSEGPLNSVNAQLSGLNVSSQSPVITNNLYPSLQPQMDLLASEDTEVPTLFPQRTSQNLASSHTYDNFPDHSSSVLLQPVSLHTAPAAPSSQRLPPLPSNHPVLKNSALQPPSYYEVMEFDPLAPTTEAIYEEIDASHKKGAQSHSEC
uniprot
proteins
function
FUNCTION: Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
52551
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosines by FYN and LYN. {ECO:0000269|PubMed:17977829}.
uniprot
proteins
protein_family
TOM1 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
17977829
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
475
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack {ECO:0000250}. Endosome membrane {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:17977829}. Membrane {ECO:0000269|PubMed:17977829}; Peripheral membrane protein {ECO:0000269|PubMed:17977829}; Cytoplasmic side {ECO:0000269|PubMed:17977829}. Note=A small proportion is membrane-associated.
uniprot
proteins