CPLANE2
entrez
79363
canonical
uniprot
Q9BU20
canonical
ensembl
ENSG00000132881
resolver
ensembl
ENSG00000291382
resolver
ensp
ENSP00000364749
resolver
ensp
ENSP00000516858
resolver
ensp
ENSP00000656637
resolver
enst
ENST00000375599
resolver
enst
ENST00000707390
resolver
genesymbol
CPLANE2
resolver
genesymbol_syn
C1orf89
resolver
genesymbol_syn
RSG1
resolver
hgnc
HGNC:28127
resolver
uniprot
Q5TEV7
resolver
uniprot_entry
CPLN2_HUMAN
resolver
uniprot_sec
Q5TEV7
resolver
amino_acid_sequence
MARPPVPGSVVVPNWHESAEGKEYLACILRKNRRRVFGLLERPVLLPPVSIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGLAEQLWHQDQVAAGLLPNPPESAPE
uniprot
proteins
function
FUNCTION: Required for efficient primary cilia initiation, regulating a late step in cilia initiation. Plays a role in the final maturation of the mother centriole and ciliary vesicle that allows extension of the ciliary axoneme. {ECO:0000250|UniProtKB:A2A825}.
uniprot
proteins
mass_dalton
28498
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
27717682
uniprot
proteins
pubmed
29038301
uniprot
proteins
pubmed
35427153
uniprot
proteins
sequence_length
258
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:29038301}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:29038301}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme (PubMed:29038301). Recruitment to the centriole depends on TTBK2, INTU, and its own GTPase activity (By similarity). {ECO:0000250|UniProtKB:A2A825, ECO:0000269|PubMed:29038301}.
uniprot
proteins