Pllp
entrez
64364
canonical
uniprot
P47987
canonical
ensembl
ENSRNOG00055022150
resolver
ensembl
ENSRNOG00060016116
resolver
ensembl
ENSRNOG00065003642
resolver
ensp
ENSRNOP00055031057
resolver
ensp
ENSRNOP00060022171
resolver
ensp
ENSRNOP00065003814
resolver
enst
ENSRNOT00055038064
resolver
enst
ENSRNOT00060027593
resolver
enst
ENSRNOT00065005282
resolver
genesymbol
Pllp
resolver
genesymbol_syn
Pmlp
resolver
genesymbol_syn
Tm4sf11
resolver
uniprot_entry
PLLP_RAT
resolver
amino_acid_sequence
MAEFPSKVSTRTSSPAQGVGASVSAMRPDLGFVRSALGVLALLQLVLGLLVWALIADTPYHLYPAYGWVMFVAVFLWLVTIVFFIIYLFQLHMKLYMVPWPLVLLVFFVAATVLYITAFVACAAAVDLTSLRGSRPYNQRSAASFFACLVMIAYGLSAFFSFQAWRGVGSNAATSQMAGGYS
uniprot
proteins
function
FUNCTION: Main component of the myelin sheath that plays an important role in myelin membrane biogenesis and myelination (Probable). Plays an essential function in apical endocytosis. Regulates epithelial development through the regulation of apical endocytosis (By similarity). Part of the intracellular machinery that mediates basolateral-to-apical transport of ICAM-1, an essential adhesion receptor in epithelial cells, from the subapical compartment in hepatic epithelial cells (By similarity). {ECO:0000250|UniProtKB:A3KQ86, ECO:0000250|UniProtKB:Q9Y342, ECO:0000305|PubMed:8714710}.
uniprot
proteins
mass_dalton
19834
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000269|PubMed:12871592}.
uniprot
proteins
protein_family
MAL family
uniprot
proteins
pubmed
12871592
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
7929173
uniprot
proteins
pubmed
8714710
uniprot
proteins
sequence_length
182
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9Y342}; Multi-pass membrane protein {ECO:0000255}. Myelin membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:12871592}; Multi-pass membrane protein {ECO:0000255}. Note=In polarized cells, localized predominantly in the apical membrane (PubMed:12871592). Located in lipid raft (PubMed:12871592). Recycled between the plasma membrane and the Golgi complex (By similarity). PLLP is continuously recirculating in the cell (By similarity). {ECO:0000250|UniProtKB:Q9Y342, ECO:0000269|PubMed:12871592}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..56; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 69..89; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 142..162; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins