Slc36a2
entrez
246049
canonical
uniprot
Q8BHK3
canonical
ensembl
ENSMUSG00000020264
resolver
ensp
ENSMUSP00000045613
resolver
ensp
ENSMUSP00000269340
resolver
ensp
ENSMUSP00000269349
resolver
genesymbol
Slc36a2
resolver
genesymbol_syn
Pat2
resolver
genesymbol_syn
Tramd1
resolver
uniprot
Q8BUB0
resolver
uniprot
Q8JZP1
resolver
uniprot_entry
S36A2_MOUSE
resolver
uniprot_sec
Q8BUB0
resolver
uniprot_sec
Q8JZP1
resolver
amino_acid_sequence
MSVTKSARSPQVATPLNLDLPESAKKLQSQDPSPANGSSSESSKKTKGITGFQTLVHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLNKPFMDYGDTVMHGLAFSPNAWLQNHAHWGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETVVLTPTMDSRLYMLSFLPVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQYIIQEIPDASQLPLVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDARGFPTILSLGMSIITTLYIAIGALGYLRFGDDIKASITLNLPNCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQVSKRWALPVDLSIRLALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYGEGISPLTVTKDALISILGFMGFVVGTYQALDELIKSGNSPALSNSTMFIQ
uniprot
proteins
function
FUNCTION: Electrogenic proton/amino acid symporter with a high selectivity for the small side chains amino acids glycine, alanine and proline, where both L- and D-enantiomers are transported. Extension of the backbone length, as in beta-alanine and 4-aminobutanoate or methylation of the amino group, as in sarcosine and N,N-dimethylglycine, are also tolerated but decrease transport efficiency. A free carboxyl group is preferred. {ECO:0000269|PubMed:11959859, ECO:0000269|PubMed:12809675, ECO:0000269|PubMed:14600155, ECO:0000269|PubMed:15291811}.
uniprot
proteins
mass_dalton
52063
uniprot
proteins
protein_family
Amino acid/polyamine transporter 2 family
uniprot
proteins
pubmed
11959859
uniprot
proteins
pubmed
12451123
uniprot
proteins
pubmed
12809675
uniprot
proteins
pubmed
14600155
uniprot
proteins
pubmed
15058382
uniprot
proteins
pubmed
15291811
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
478
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11959859, ECO:0000269|PubMed:14600155}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:14600155}. Recycling endosome membrane {ECO:0000269|PubMed:14600155}.
uniprot
proteins
transmembrane_region
TRANSMEM 54..74; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 144..164; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 193..213; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 218..238; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 260..280; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 293..313; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 341..361; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 375..395; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 400..420; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 442..462; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins