Cldn15
entrez
304388
canonical
uniprot
D3ZQJ0
canonical
ensembl
ENSRNOG00000001419
resolver
ensembl
ENSRNOG00065001635
resolver
ensp
ENSRNOP00000001923
resolver
ensp
ENSRNOP00065001544
resolver
enst
ENSRNOT00000001923
resolver
enst
ENSRNOT00065002201
resolver
genesymbol
Cldn15
resolver
uniprot_entry
CLD15_RAT
resolver
amino_acid_sequence
MSIAVETFGFFMSALGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRCTNVGNIDLSRKAKLLAIAGAFHILAGACGMVAISWYAVNITTDFFNPLYVGTKYELGSALYLGWSASLLSILGGICVFSTCCCDSKEDPATRVGLPYKPSTVVTARATSDESDVSFGKYGKNAYV
uniprot
proteins
function
FUNCTION: Forms paracellular channels: polymerizes in tight junction strands with cation- and water-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability (By similarity). In intestinal epithelium, allows for sodium and water fluxes from the peritoneal side to the lumen of the intestine to regulate nutrient absorption and intestinal morphogenesis (By similarity). {ECO:0000250|UniProtKB:P56746, ECO:0000250|UniProtKB:Q9Z0S5}.
uniprot
proteins
mass_dalton
24312
uniprot
proteins
post_translational_modification
PTM: Palmitoylated. {ECO:0000250|UniProtKB:Q9Z0S5}.
uniprot
proteins
protein_family
Claudin family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
16505581
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, tight junction {ECO:0000250|UniProtKB:P56746}. Cell membrane {ECO:0000250|UniProtKB:P56746}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 2..24; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 75..99; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 116..140; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 160..182; /note="Helical"; /evidence="ECO:0000250
uniprot
proteins