Gcsh
entrez
171133
canonical
uniprot
Q5I0P2
canonical
ensembl
ENSRNOG00000011535
resolver
ensembl
ENSRNOG00055021688
resolver
ensembl
ENSRNOG00060021071
resolver
ensembl
ENSRNOG00065006492
resolver
ensp
ENSRNOP00000015967
resolver
ensp
ENSRNOP00055030218
resolver
ensp
ENSRNOP00060030053
resolver
ensp
ENSRNOP00065007294
resolver
enst
ENSRNOT00000015967
resolver
enst
ENSRNOT00055037131
resolver
enst
ENSRNOT00060036518
resolver
enst
ENSRNOT00065010019
resolver
genesymbol
Gcsh
resolver
uniprot_entry
GCSH_RAT
resolver
amino_acid_sequence
MSLRVVRSVRAVACSLRIALASCPPRPWAPSAAAVRSLRTGSALLSVRKFTEKHEWVTAKDGIGTVGISNFAQEALGDVVYCSLPEVGTKLKKQEEFGALESVKAASELYSPLSGEVTEVNEALAENPGLVNKSCYEDGWLIKMTLSDPSELDELMSEEAYEKYVKSIEE
uniprot
proteins
function
FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Has a pivotal role in the lipoylation of enzymes involved in cellular energetics such as the mitochondrial dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (DLAT), and the mitochondrial dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (DLST). {ECO:0000250|UniProtKB:P23434}.
uniprot
proteins
mass_dalton
18485
uniprot
proteins
protein_family
GcvH family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
170
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P23434}.
uniprot
proteins