NREP
entrez
9315
canonical
uniprot
Q16612
canonical
ensembl
ENSG00000134986
resolver
ensp
ENSP00000257435
resolver
ensp
ENSP00000368993
resolver
ensp
ENSP00000378996
resolver
ensp
ENSP00000392559
resolver
ensp
ENSP00000399766
resolver
ensp
ENSP00000402965
resolver
ensp
ENSP00000408839
resolver
ensp
ENSP00000422630
resolver
ensp
ENSP00000427476
resolver
ensp
ENSP00000769816
resolver
genesymbol
NREP
resolver
genesymbol_syn
C5orf13
resolver
genesymbol_syn
P311
resolver
hgnc
HGNC:16834
resolver
uniprot
B2RDN8
resolver
uniprot
B7Z5D2
resolver
uniprot
D3DSZ8
resolver
uniprot_entry
NREP_HUMAN
resolver
uniprot_sec
B2RDN8
resolver
uniprot_sec
B7Z5D2
resolver
uniprot_sec
D3DSZ8
resolver
amino_acid_sequence
MVYYPELFVWVSQEPFPNKDMEGRLPKGRLPVPKEVNRKKNDETNAASLTPLGSSELRSPRISYLHFF
uniprot
proteins
function
FUNCTION: May have roles in neural function. Ectopic expression augments motility of gliomas. Also promotes axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation. {ECO:0000250, ECO:0000269|PubMed:11358844, ECO:0000269|PubMed:16229809}.
uniprot
proteins
mass_dalton
7909
uniprot
proteins
mutagenesis
MUTAGEN 59; /note="S->A: Reduces protein degradation and induces glioma cell migration."; /evidence="ECO:0000269|PubMed:16229809"; MUTAGEN 59; /note="S->D: Accelerates protein degradation and reduces glioma cell migration."; /evidence="ECO:0000269|PubMed:16229809
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on Ser-59. Phosphorylation decreases stability and activity. {ECO:0000269|PubMed:16229809}.
uniprot
proteins
pubmed
11358844
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16229809
uniprot
proteins
pubmed
16484684
uniprot
proteins
sequence_length
68
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11358844}.
uniprot
proteins