SEC14L2
entrez
23541
canonical
uniprot
O76054
canonical
ensembl
ENSG00000100003
resolver
ensp
ENSP00000383882
resolver
ensp
ENSP00000385186
resolver
ensp
ENSP00000478755
resolver
ensp
ENSP00000482467
resolver
genesymbol
SEC14L2
resolver
genesymbol_syn
C22orf6
resolver
genesymbol_syn
KIAA1186
resolver
genesymbol_syn
KIAA1658
resolver
hgnc
HGNC:10699
resolver
uniprot
B7Z3Z8
resolver
uniprot
B7Z8Q1
resolver
uniprot
F5H3U4
resolver
uniprot
Q53EQ2
resolver
uniprot
Q6PD61
resolver
uniprot
Q9ULN4
resolver
uniprot_entry
B7Z3Z8_HUMAN
resolver
uniprot_entry
S14L2_HUMAN
resolver
uniprot_sec
B7Z8Q1
resolver
uniprot_sec
F5H3U4
resolver
uniprot_sec
Q53EQ2
resolver
uniprot_sec
Q6PD61
resolver
uniprot_sec
Q9ULN4
resolver
amino_acid_sequence
MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK
uniprot
proteins
function
FUNCTION: Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
uniprot
proteins
mass_dalton
46145
uniprot
proteins
pubmed
10574461
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
10829015
uniprot
proteins
pubmed
11226224
uniprot
proteins
pubmed
11444841
uniprot
proteins
pubmed
12429094
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
403
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
uniprot
proteins