Steap2
entrez
74051
canonical
uniprot
Q8BWB6
canonical
ensembl
ENSMUSG00000015653
resolver
ensp
ENSMUSP00000015797
resolver
ensp
ENSMUSP00000111084
resolver
ensp
ENSMUSP00000111085
resolver
ensp
ENSMUSP00000111086
resolver
ensp
ENSMUSP00000111087
resolver
ensp
ENSMUSP00000116910
resolver
ensp
ENSMUSP00000132501
resolver
ensp
ENSMUSP00000274260
resolver
enst
ENSMUST00000015797
resolver
enst
ENSMUST00000115424
resolver
enst
ENSMUST00000115425
resolver
enst
ENSMUST00000115426
resolver
enst
ENSMUST00000115427
resolver
enst
ENSMUST00000164219
resolver
genesymbol
Steap2
resolver
uniprot
B2RX33
resolver
uniprot
D3YUM6
resolver
uniprot
Q3TS12
resolver
uniprot_entry
B2RX33_MOUSE
resolver
uniprot_entry
D3YUM6_MOUSE
resolver
uniprot_entry
STEA2_MOUSE
resolver
uniprot_sec
Q3TS12
resolver
amino_acid_sequence
MESISMMGSPKSLETFLPNGINGIKDARQVTVGVIGSGDFAKSLTIRLIRCGYHVVIGSRNPKFASEFFPHVVDVTHHEDALTKTNIIFVAIHREHYTSLWDLRHLLVGKILIDVSNNMRVNQYPESNAEYLASLFPDSLIVKGFNVISAWALQLGPKDASRQVYICSNNIQARQQVIELARQLNFIPVDLGSLSSAKEIENLPLRLFTLWRGPVVVAISLATFFFLYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAGLLAAAYQLYYGTKYRRFPPWLDTWLQCRKQLGLLSFFFAVVHVAYSLCLPMRRSERYLFLNMAYQQVHANIENAWNEEEVWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALNWREFSFIQSTLGYVALLITTFHVLIYGWKRAFAEEYYRFYTPPNFVLALVLPSIVILGKMILLLPCISRKLKRIKKGWEKSQFLDEGMGGAVPHLSPERVTVM
uniprot
proteins
ec_number
1.16.1.-
uniprot
proteins
function
FUNCTION: Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane (PubMed:16609065). Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity). Can also reduce Cu(2+) to Cu(1+) (PubMed:16609065). {ECO:0000250|UniProtKB:Q687X5, ECO:0000269|PubMed:16609065}.
uniprot
proteins
mass_dalton
55760
uniprot
proteins
protein_family
STEAP family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16609065
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
489
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16609065}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:16609065}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 207..227; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 304..324; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 358..378; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 392..412; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 431..451; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins