Actn1
entrez
81634
canonical
uniprot
Q9Z1P2
canonical
ensembl
ENSRNOG00000056756
resolver
ensembl
ENSRNOG00055019526
resolver
ensembl
ENSRNOG00060022661
resolver
ensembl
ENSRNOG00065018793
resolver
ensp
ENSRNOP00000068851
resolver
ensp
ENSRNOP00000074946
resolver
ensp
ENSRNOP00055027565
resolver
ensp
ENSRNOP00060035693
resolver
ensp
ENSRNOP00065026056
resolver
enst
ENSRNOT00000079824
resolver
enst
ENSRNOT00000091560
resolver
enst
ENSRNOT00055033944
resolver
enst
ENSRNOT00060043134
resolver
enst
ENSRNOT00065032631
resolver
genesymbol
Actn1
resolver
uniprot
A0A0G2JTU7
resolver
uniprot
Q6GMN8
resolver
uniprot
Q6T487
resolver
uniprot_entry
A0A0G2JTU7_RAT
resolver
uniprot_entry
ACTN1_RAT
resolver
uniprot_entry
Q6GMN8_RAT
resolver
uniprot_entry
Q6T487_RAT
resolver
amino_acid_sequence
MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMQAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHSRQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITGDELRRELPPDQAEYCIARMAPYAGPDSVPGALDYMSFSTALYGESDL
uniprot
proteins
function
FUNCTION: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. Association with IGSF8 regulates the immune synapse formation and is required for efficient T-cell activation. {ECO:0000250|UniProtKB:P12814}.
uniprot
proteins
mass_dalton
102960
uniprot
proteins
protein_family
Alpha-actinin family
uniprot
proteins
pubmed
14729062
uniprot
proteins
pubmed
15505042
uniprot
proteins
pubmed
16464232
uniprot
proteins
pubmed
21210813
uniprot
proteins
pubmed
22659164
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
892
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21210813}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:P12814}. Cell membrane {ECO:0000269|PubMed:21210813}. Cell junction {ECO:0000269|PubMed:21210813}. Cell projection, ruffle {ECO:0000250|UniProtKB:Q7TPR4}. Note=Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. Colocalizes with PSD in membrane ruffles and central reticular structures. {ECO:0000250|UniProtKB:Q7TPR4}.
uniprot
proteins