ADAM18
entrez
8749
canonical
uniprot
Q9Y3Q7
canonical
ensembl
ENSG00000168619
resolver
ensembl
ENSG00000278548
resolver
ensp
ENSP00000265707
resolver
ensp
ENSP00000369195
resolver
ensp
ENSP00000429908
resolver
genesymbol
ADAM18
resolver
genesymbol_syn
TMDC3
resolver
hgnc
HGNC:196
resolver
uniprot
B2R9Y0
resolver
uniprot
Q0VAI3
resolver
uniprot
Q0VAI4
resolver
uniprot
Q6IRW9
resolver
uniprot
Q6UXJ9
resolver
uniprot_entry
ADA18_HUMAN
resolver
uniprot_entry
Q0VAI3_HUMAN
resolver
uniprot_sec
B2R9Y0
resolver
uniprot_sec
Q0VAI4
resolver
uniprot_sec
Q6IRW9
resolver
uniprot_sec
Q6UXJ9
resolver
amino_acid_sequence
MFLLLALLTELGRLQAHEGSEGIFLHVTVPRKIKSNDSEVSERKMIYIITIDGQPYTLHLGKQSFLPQNFLVYTYNETGSLHSVSPYFMMHCHYQGYAAEFPNSFVTLSICSGLRGFLQFENISYGIEPVESSARFEHIIYQMKNNDPNVSILAVNYSHIWQKDQPYKVPLNSQIKNLSKLLPQYLEIYIIVEKALYDYMGSEMMAVTQKIVQVIGLVNTMFTQFKLTVILSSLELWSNENQISTSGDADDILQRFLAWKRDYLILRPHDIAYLLVYRKHPKYVGATFPGTVCNKSYDAGIAMYPDAIGLEGFSVIIAQLLGLNVGLTYDDITQCFCLRATCIMNHEAVSASGRKIFSNCSMHDYRYFVSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDYNTCKLKGSVKCGSGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNCVPDTYALNGRLCKLGTAYCYNGQCQTTDNQCAKIFGKGAQGAPFACFKEVNSLHERSENCGFKNSQPLPCERKDVLCGKLACVQPHKNANKSDAQSTVYSYIQDHVCVSIATGSSMRSDGTDNAYVADGTMCGPEMYCVNKTCRKVHLMGYNCNATTKCKGKGICNNFGNCQCFPGHRPPDCKFQFGSPGGSIDDGNFQKSGDFYTEKGYNTHWNNWFILSFCIFLPFFIVFTTVIFKRNEISKSCNRENAEYNRNSSVVSESDDVGH
uniprot
proteins
function
FUNCTION: Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
82856
uniprot
proteins
post_translational_modification
PTM: The prodomain and the metalloprotease-like domain are cleaved during the epididymal maturation of the spermatozoa. {ECO:0000250}.
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
21618342
uniprot
proteins
sequence_length
739
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 688..708; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins