Slc22a16
entrez
70840
canonical
uniprot
Q497L8
canonical
ensembl
ENSMUSG00000019834
resolver
ensp
ENSMUSP00000077428
resolver
ensp
ENSMUSP00000356487
resolver
genesymbol
Slc22a16
resolver
uniprot
B2RRB7
resolver
uniprot
Q3LVC1
resolver
uniprot_entry
B2RRB7_MOUSE
resolver
uniprot_entry
S22AG_MOUSE
resolver
uniprot_sec
Q3LVC1
resolver
amino_acid_sequence
MESCNVELIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWRLEDILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSHLGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMALWCTSIGVFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLLKTWWLYQIILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSCDLVELLSLDVTRSHNKSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLGYYMFGKEVIRRKENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALLVKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQQVPENKDSLGEGPPDSFERWDSSRALSFAERWGLSRASPDAEKWGSGRVPPDAGKWGAGIAPPVTERGASGRASLEDESGGSGRAPPEKNTEMENEIENMKVSNLGGF
uniprot
proteins
function
FUNCTION: Facilitative organic cation transporter that mediates the transport of carnitine as well as the polyamine spermidine. Mediates the partially Na(+)-dependent bidirectional transport of carnitine. May mediate L-carnitine secretion from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. {ECO:0000250|UniProtKB:Q86VW1}.
uniprot
proteins
mass_dalton
73933
uniprot
proteins
protein_family
Major facilitator (TC 2.A.1) superfamily
uniprot
proteins
protein_family
Organic cation transporter (TC 2.A.1.19) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
649
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q86VW1}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q86VW1}. Note=Detected in the plasma membrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis. {ECO:0000250|UniProtKB:Q86VW1}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 156..176; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 214..234; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 244..264; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 268..288; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 356..376; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 389..409; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 417..437; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 445..465; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 475..495; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 501..521; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins