Mppe1
entrez
361344
canonical
uniprot
B1WC86
canonical
ensembl
ENSRNOG00000018648
resolver
ensembl
ENSRNOG00055010113
resolver
ensembl
ENSRNOG00060010576
resolver
ensembl
ENSRNOG00065020120
resolver
ensp
ENSRNOP00000025164
resolver
ensp
ENSRNOP00055013714
resolver
ensp
ENSRNOP00060013880
resolver
ensp
ENSRNOP00065027153
resolver
enst
ENSRNOT00055017053
resolver
enst
ENSRNOT00060017874
resolver
enst
ENSRNOT00065033933
resolver
genesymbol
Mppe1
resolver
genesymbol_syn
Pgap5
resolver
uniprot_entry
MPPE1_RAT
resolver
amino_acid_sequence
MALVRWGLRRQNFHLLRRRRVLLLKLTVVVISVLLFCEYFIYYLVLFRCHWPEVKMPARGGRQEPVLKAMFLADTHLLGEIRGHWLDKLRREWQMERAFQTALWLLQPEVVFILGDVFDEGKWSSAQAWADDLHRFQRMFRHGSHVQLKVVIGNHDIGFHYQMSKYRINRFEKVFGSERLFSLKGVNFVMVNSVAMEGDGCTICSEAEAELREISRKLNCSQEQVQGSSQCDHEPRLPLSAPVLLQHYPLYRASDANCSGEDAAPPEERSVPFEEKYDVLSREASQKLLWWLRPRLILSGHTHSACEVLHPGGAPEVSVPSFSWRNRNNPSFIMGSLTSRDYALSKCYLPCEDTVLTTYCAAAAFLLVLILAHFERLPSSFLFGWKLCRSHLRR
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Metallophosphoesterase that catalyzes the removal of a side-chain ethanolamine-phosphate (EtNP) from the second mannose of the GPI-anchor protein intermediate. Participates in the glycan remodeling steps of GPI-anchor maturation to allow an efficient transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. {ECO:0000250|UniProtKB:Q53F39}.
uniprot
proteins
mass_dalton
45654
uniprot
proteins
protein_family
MPPE1 family
uniprot
proteins
protein_family
Metallophosphoesterase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
394
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q53F39}; Multi-pass membrane protein {ECO:0000255}. Note=Also localizes to endoplasmic reticulum exit site. {ECO:0000250|UniProtKB:Q53F39}.
uniprot
proteins
transmembrane_region
TRANSMEM 27..47; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 354..374; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins