Med22
entrez
20933
canonical
uniprot
Q62276
canonical
ensembl
ENSMUSG00000015776
resolver
ensp
ENSMUSP00000015920
resolver
ensp
ENSMUSP00000099963
resolver
ensp
ENSMUSP00000217276
resolver
genesymbol
Med22
resolver
genesymbol_syn
Surf5
resolver
uniprot
A2ALA2
resolver
uniprot
Q3TTZ9
resolver
uniprot_entry
MED22_MOUSE
resolver
uniprot_sec
A2ALA2
resolver
uniprot_sec
Q3TTZ9
resolver
amino_acid_sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLITLRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDADSADGLSAPLLASPETGAGPLQSAAPVHSHGGGPGPTEHT
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
22282
uniprot
proteins
protein_family
Mediator complex subunit 22 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8586415
uniprot
proteins
sequence_length
200
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins