Tssk6
entrez
83984
canonical
uniprot
Q925K9
canonical
ensembl
ENSMUSG00000047654
resolver
ensp
ENSMUSP00000062783
resolver
enst
ENSMUST00000050373
resolver
genesymbol
Tssk6
resolver
genesymbol_syn
Sstk
resolver
uniprot
Q5RL09
resolver
uniprot
Q8C625
resolver
uniprot_entry
TSSK6_MOUSE
resolver
uniprot_sec
Q5RL09
resolver
uniprot_sec
Q8C625
resolver
amino_acid_sequence
MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGSQARELFSQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKITDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSLGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPDGLELSERCKSLIAELLQFSPSARPSAGQVARNGWLRAGDSG
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Serine/threonine-protein kinase component of the sperm flagellar doublet microtubules (PubMed:15870294, PubMed:37295417). May act as a regulator of sperm motility by mediating phosphorylation of sperm doublet microtubule proteins (PubMed:37295417). Plays a role in DNA condensation during postmeiotic chromatin remodeling and histone-to-protamine transition during spermatogenesis (PubMed:15870294, PubMed:28389581). {ECO:0000269|PubMed:15870294, ECO:0000269|PubMed:28389581, ECO:0000269|PubMed:37295417}.
uniprot
proteins
mass_dalton
30287
uniprot
proteins
post_translational_modification
PTM: Autophosphorylated. {ECO:0000250|UniProtKB:Q9BXA6}.; PTM: Ubiquitinated; HSP90 activity negatively regulates ubiquitination and degradation. {ECO:0000269|PubMed:23599433}.
uniprot
proteins
protein_family
CAMK Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15870294
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
23599433
uniprot
proteins
pubmed
28389581
uniprot
proteins
pubmed
37295417
uniprot
proteins
sequence_length
273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37295417}. Nucleus {ECO:0000269|PubMed:28389581}. Note=Component of the sperm flagellar doublet microtubules (PubMed:37295417). Also localizes in the nucleus of elongating spermatids (PubMed:28389581). {ECO:0000269|PubMed:28389581, ECO:0000269|PubMed:37295417}.
uniprot
proteins