Clec9a
entrez
232414
canonical
uniprot
Q8BRU4
canonical
ensembl
ENSMUSG00000046080
resolver
ensp
ENSMUSP00000056625
resolver
ensp
ENSMUSP00000085394
resolver
ensp
ENSMUSP00000128622
resolver
ensp
ENSMUSP00000144990
resolver
genesymbol
Clec9a
resolver
genesymbol_syn
Dngr-1
resolver
uniprot
B0ZBM3
resolver
uniprot
B0ZBM5
resolver
uniprot
B0ZBM6
resolver
uniprot
B0ZBM7
resolver
uniprot
Q5M8M6
resolver
uniprot
Q8CBB4
resolver
uniprot_entry
CLC9A_MOUSE
resolver
uniprot_sec
B0ZBM3
resolver
uniprot_sec
B0ZBM5
resolver
uniprot_sec
B0ZBM6
resolver
uniprot_sec
B0ZBM7
resolver
uniprot_sec
Q5M8M6
resolver
uniprot_sec
Q8CBB4
resolver
amino_acid_sequence
MHAEEIYTSLQWDIPTSEASQKCQSPSKCSGAWCVVTMISCVVCMGLLATSIFLGIKFFQVSSLVLEQQERLIQQDTALVNLTQWQRKYTLEYCQALLQRSLHSGSDCSPCPHNWIQNGKSCYYVFERWEMWNISKKSCLKEGASLFQIDSKEEMEFISSIGKLKGGNKYWVGVFQDGISGSWFWEDGSSPLSDLLPAERQRSAGQICGYLKDSTLISDKCDSWKYFICEKKAFGSCI
uniprot
proteins
function
FUNCTION: Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. {ECO:0000269|PubMed:18408006, ECO:0000269|PubMed:18497879, ECO:0000269|PubMed:19219027, ECO:0000269|PubMed:22483802}.
uniprot
proteins
mass_dalton
27014
uniprot
proteins
mutagenesis
MUTAGEN 7; /note="Y->F: Abolishes the recruitment and activation of the tyrosine kinase Syk."; /evidence="ECO:0000269|PubMed:19219027
uniprot
proteins
post_translational_modification
PTM: [Isoform 1]: Not glycosylated.; PTM: [Isoform 4]: N-glycosylated.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18408006
uniprot
proteins
pubmed
18497879
uniprot
proteins
pubmed
19219027
uniprot
proteins
pubmed
22483802
uniprot
proteins
sequence_length
238
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:18408006}; Single-pass type II membrane protein {ECO:0000269|PubMed:18408006}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..56; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins