Pfn3
entrez
75477
canonical
uniprot
Q9DAD6
canonical
ensembl
ENSMUSG00000044444
resolver
ensp
ENSMUSP00000054053
resolver
enst
ENSMUST00000054146
resolver
genesymbol
Pfn3
resolver
uniprot_entry
PROF3_MOUSE
resolver
amino_acid_sequence
MSDWKGYISAVLRDQRIDDVAIVGHSDNRCVWASRPGGLLAAISPQEVGVLTGPDRHTFLQTGLSVAGRRCCVIRDYLLAEGDGVLDARTKGLDGRAICVGHTPRALLVLMGRRGVHGGILNKTVHDLIGGLREQCS
uniprot
proteins
function
FUNCTION: Binds to actin and affects the structure of the cytoskeleton. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). Slightly reduces actin polymerization. May be involved in spermatogenesis. {ECO:0000250}.
uniprot
proteins
mass_dalton
14697
uniprot
proteins
protein_family
Profilin family
uniprot
proteins
pubmed
11867228
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18692047
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
137
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000269|PubMed:18692047}.
uniprot
proteins