Slc4a3
entrez
20536
canonical
uniprot
P16283
canonical
ensembl
ENSMUSG00000006576
resolver
ensp
ENSMUSP00000116747
resolver
ensp
ENSMUSP00000306851
resolver
ensp
ENSMUSP00000306854
resolver
ensp
ENSMUSP00000306856
resolver
ensp
ENSMUSP00000306883
resolver
genesymbol
Slc4a3
resolver
genesymbol_syn
Ae3
resolver
uniprot
Q68EG4
resolver
uniprot
Q9ERP4
resolver
uniprot
Q9ERP5
resolver
uniprot_entry
B3A3_MOUSE
resolver
uniprot_entry
Q68EG4_MOUSE
resolver
uniprot_entry
Q9ERP4_MOUSE
resolver
uniprot_sec
Q9ERP5
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS). {ECO:0000269|PubMed:2686841}.
uniprot
proteins
amino_acid_sequence
MANGVIPPPGGASPLPQVRVPLEEPPLGPDVEEEDDDLGKTLAVSRFGDLISKTPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRPPPTSARHTRRKRKKEKTSAPPSEGTPPIQEEGGAGAEEEEEEEEEEEGESEAEPVEPLPPGPPQKAKFSIGSDEDDSPGLPVKAPCAKALPSVGLQSDQSPQRSGSSPSPRARASRISTEKSRPWSPSASYDLRERLCPGSALGNPGPEQRVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRIQGGRGSPSGLAPILRRKKKKKKLDRRPHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAQGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRNPSSSSVNSVLGNHHPTPSHGPDGAVPTMADDQGEPAPLWPHDPDAKEKPLHMPGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLSEAVLLESVLEVPVPVRFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLGAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYAAPGKELSLEMGGSEATSEDDPLQRTGSVFGGLVRDVKRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFHKLYKVFTEHPLLPFYPPDEALETGLELNSSALPPTEGPPGPRNQPNTALLSLILMLGTFLIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPHKRTWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLLIFMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRRCLLPRLFQDRELQALDSEDAEPNFDEDGQDEYNELHMPV
uniprot
proteins
function
FUNCTION: Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane. May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential (By similarity). {ECO:0000250|UniProtKB:P48751, ECO:0000269|PubMed:2686841}.
uniprot
proteins
mass_dalton
135373
uniprot
proteins
protein_family
Anion exchanger (TC 2.A.31) family
uniprot
proteins
pubmed
12592704
uniprot
proteins
pubmed
17114649
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
2686841
uniprot
proteins
pubmed
8126106
uniprot
proteins
sequence_length
1227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:2686841}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 708..730; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 736..773; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 793..815; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 825..846; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 888..905; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 921..941; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 975..997; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1023..1044; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1078..1123; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1150..1186; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins