Rgn
entrez
19733
canonical
uniprot
Q64374
canonical
ensembl
ENSMUSG00000023070
resolver
ensp
ENSMUSP00000023832
resolver
ensp
ENSMUSP00000258137
resolver
ensp
ENSMUSP00000258139
resolver
ensp
ENSMUSP00000258140
resolver
ensp
ENSMUSP00000258142
resolver
enst
ENSMUST00000023832
resolver
genesymbol
Rgn
resolver
genesymbol_syn
Smp30
resolver
uniprot
A2AFC8
resolver
uniprot
Q3UJG3
resolver
uniprot
Q60944
resolver
uniprot_entry
RGN_MOUSE
resolver
uniprot_sec
A2AFC8
resolver
uniprot_sec
Q3UJG3
resolver
uniprot_sec
Q60944
resolver
amino_acid_sequence
MSSIKVECVLRENYRCGESPVWEEASQSLLFVDIPSKIICRWDTVSNQVQRVAVDAPVSSVALRQLGGYVATIGTKFCALNWENQSVFVLAMVDEDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYSLFPDHSVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYTVDAFDYDLQTGQISNRRIVYKMEKDEQIPDGMCIDAEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDYSEMYVTCARDGLNAEGLLRQPDAGNIFKITGLGVKGIAPYSYAG
uniprot
proteins
ec_number
3.1.1.17
uniprot
proteins
function
FUNCTION: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). {ECO:0000250, ECO:0000269|PubMed:16585534, ECO:0000269|PubMed:23349732}.
uniprot
proteins
mass_dalton
33407
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; L-ascorbate biosynthesis via UDP-alpha-D-glucuronate pathway; L-ascorbate from UDP-alpha-D-glucuronate: step 3/4. {ECO:0000269|PubMed:16585534, ECO:0000269|PubMed:23349732}.
uniprot
proteins
protein_family
SMP-30/CGR1 family
uniprot
proteins
pubmed
14975739
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16585534
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23349732
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
8765750
uniprot
proteins
pubmed
9278263
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins