Ptp4a1
entrez
29463
canonical
uniprot
Q78EG7
canonical
ensembl
ENSRNOG00000011771
resolver
ensembl
ENSRNOG00000086578
resolver
ensembl
ENSRNOG00055001636
resolver
ensembl
ENSRNOG00060026808
resolver
ensembl
ENSRNOG00065010876
resolver
ensp
ENSRNOP00000016237
resolver
ensp
ENSRNOP00000103143
resolver
ensp
ENSRNOP00055001950
resolver
ensp
ENSRNOP00060038679
resolver
ensp
ENSRNOP00065013565
resolver
enst
ENSRNOT00000016237
resolver
enst
ENSRNOT00000161172
resolver
enst
ENSRNOT00055002621
resolver
enst
ENSRNOT00060046525
resolver
enst
ENSRNOT00065017676
resolver
genesymbol
Ptp4a1
resolver
genesymbol_syn
Prl1
resolver
uniprot
Q4QRA5
resolver
uniprot
Q8VH48
resolver
uniprot_entry
TP4A1_RAT
resolver
uniprot_sec
Q4QRA5
resolver
uniprot_sec
Q8VH48
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by sodium orthovanadate and pentamidine. {ECO:0000269|PubMed:8196618}.
uniprot
proteins
amino_acid_sequence
MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
19815
uniprot
proteins
mutagenesis
MUTAGEN 104; /note="C->S: Abolishes enzymatic activity."; /evidence="ECO:0000269|PubMed:8196618
uniprot
proteins
post_translational_modification
PTM: Farnesylated. Farnesylation is required for membrane targeting (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
10679780
uniprot
proteins
pubmed
10960362
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16142898
uniprot
proteins
pubmed
8196618
uniprot
proteins
pubmed
8840018
uniprot
proteins
sequence_length
173
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q93096}. Early endosome {ECO:0000250|UniProtKB:Q93096}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q93096}. Cytoplasm {ECO:0000250|UniProtKB:Q93096}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q93096}. Nucleus {ECO:0000269|PubMed:8196618}. Note=And mitotic spindle. {ECO:0000250|UniProtKB:Q93096}.
uniprot
proteins