Syap1
entrez
67043
canonical
uniprot
Q9D5V6
canonical
ensembl
ENSMUSG00000031357
resolver
ensp
ENSMUSP00000033723
resolver
enst
ENSMUST00000033723
resolver
genesymbol
Syap1
resolver
uniprot
Q3UI67
resolver
uniprot
Q9D870
resolver
uniprot_entry
SYAP1_MOUSE
resolver
uniprot_sec
Q3UI67
resolver
uniprot_sec
Q9D870
resolver
amino_acid_sequence
MFGGLSSWLGLKPPEGAAAEGEEPPSRDGDKLSAGAAPSEESPERPVEPTEEQQQQPPTEDPQFLHQAKGLGNYLYNFASAATKKITESVTETAQTIKKSVEEGKIDDILDKTILGDFQKEQKKFVEEQNTKKSEAAVPPWVESHDEETIQQQILALSADKRNFLRDPPAGVQFNFDFDQMYPVALVMLQEDELLSKMRFALVPKLVKEEVFWRNYFYRISLIKQSAQLTALAAQQQASGKEEKSSNRDDNLPLTEAVRPKTPPVVIKSQLKSQEDEEEISTSPGVSEFVSDAFDTCSLNQEDLRKEMEQLVLDKKQEEATALEEDSTDWEKELQQELQEYEVVAESEKRDENWDKEIEKMLQES
uniprot
proteins
function
FUNCTION: Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation (PubMed:23300339). {ECO:0000269|PubMed:23300339}.
uniprot
proteins
mass_dalton
41350
uniprot
proteins
post_translational_modification
PTM: Phosphorylated (PubMed:23300339). Phosphorylation increases in a mTORC2-mediated manner in response to epidermal growth factor (EGF) stimulation (PubMed:23300339). {ECO:0000269|PubMed:23300339}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23300339
uniprot
proteins
pubmed
27344443
uniprot
proteins
sequence_length
365
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000269|PubMed:27344443}. Golgi apparatus {ECO:0000269|PubMed:27344443}. Perikaryon {ECO:0000269|PubMed:27344443}. Cell projection, axon {ECO:0000269|PubMed:27344443}. Cell projection, dendrite {ECO:0000269|PubMed:27344443}. Cell projection, growth cone {ECO:0000269|PubMed:27344443}. Presynaptic cell membrane {ECO:0000269|PubMed:27344443}. Postsynaptic cell membrane {ECO:0000269|PubMed:27344443}. Membrane {ECO:0000250|UniProtKB:Q96A49}. Note=Localizes to cholinergic neuromuscular junctions and in actin-rich growth cone regions (PubMed:27344443). Membrane-associated in a epidermal growth factor (EGF)-dependent manner (By similarity). {ECO:0000250|UniProtKB:Q96A49, ECO:0000269|PubMed:27344443}.
uniprot
proteins