Actr8
entrez
56249
canonical
uniprot
Q8R2S9
canonical
ensembl
ENSMUSG00000015971
resolver
ensp
ENSMUSP00000016115
resolver
ensp
ENSMUSP00000153076
resolver
ensp
ENSMUSP00000310690
resolver
ensp
ENSMUSP00000310713
resolver
enst
ENSMUST00000016115
resolver
enst
ENSMUST00000224797
resolver
genesymbol
Actr8
resolver
genesymbol_syn
Arp8
resolver
uniprot
Q9CYC4
resolver
uniprot_entry
ARP8_MOUSE
resolver
uniprot_sec
Q9CYC4
resolver
amino_acid_sequence
MTQAEKGDAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVIHPGSTTLRLGRATDTLPVSVPHVIARRHKQQGQPLYKDNWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQTRSYNKQMRPAILDHCSGNKWTNTSQQPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVHMILMKMGFAGIVVHQESVCATFGSGLSSTCVVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLASSQGDCLMAGNESEEALTALMSRKTAISLFEGKALGLDKAILHSVDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW
uniprot
proteins
function
FUNCTION: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity). {ECO:0000250}.; FUNCTION: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
70546
uniprot
proteins
protein_family
ARP8 subfamily
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20971067
uniprot
proteins
sequence_length
624
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=Specifically localizes to mitotic chromosomes. {ECO:0000250}.
uniprot
proteins