Rprd1a
entrez
225283
canonical
uniprot
Q8VDS4
canonical
ensembl
ENSMUSG00000040446
resolver
ensp
ENSMUSP00000043618
resolver
ensp
ENSMUSP00000175768
resolver
enst
ENSMUST00000046206
resolver
genesymbol
Rprd1a
resolver
genesymbol_syn
Kiaa4077
resolver
genesymbol_syn
P15rs
resolver
uniprot
Q5DTP5
resolver
uniprot_entry
RPR1A_MOUSE
resolver
uniprot_sec
Q5DTP5
resolver
amino_acid_sequence
MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKHALYGDKKARKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLEKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRARIQSLPDLSRLPNVTGSHMHLPFAGDIYSED
uniprot
proteins
function
FUNCTION: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. {ECO:0000250|UniProtKB:Q96P16}.
uniprot
proteins
mass_dalton
35701
uniprot
proteins
protein_family
UPF0400 (RTT103) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
312
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q96P16}.
uniprot
proteins