Fgd4
entrez
224014
canonical
uniprot
Q91ZT5
canonical
ensembl
ENSMUSG00000022788
resolver
ensp
ENSMUSP00000069573
resolver
ensp
ENSMUSP00000125174
resolver
ensp
ENSMUSP00000179692
resolver
ensp
ENSMUSP00000329538
resolver
genesymbol
Fgd4
resolver
uniprot
A1L355
resolver
uniprot
Q3UEB6
resolver
uniprot
Q8BW60
resolver
uniprot
Q8BZI7
resolver
uniprot
Q91ZT3
resolver
uniprot
Q91ZT4
resolver
uniprot_entry
FGD4_MOUSE
resolver
uniprot_sec
A1L355
resolver
uniprot_sec
Q3UEB6
resolver
uniprot_sec
Q8BW60
resolver
uniprot_sec
Q8BZI7
resolver
uniprot_sec
Q91ZT3
resolver
uniprot_sec
Q91ZT4
resolver
amino_acid_sequence
MEESNPAPTSCTSKGKHSKVSDLISHFEGGSVLSSYIDLQKDSTMNLNIPQTLGQPGLTSSPPRKFLPQHSPQKQENDPDQTQGQHGCLANGVVAAQNQMECEDEKETTLSPEMAIQTAAASPDTHVLNGERNETITDSASSIANSHDENASDSSCRTPGTDLGLPSKEGEPGMDAELQERENGVNTMGLDTLDQHHEVKETNEQKLHKIATELLLTERAYVSRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKTMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDSPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTFQISGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIISGFTDSEEKKRRGILEIESAEVSGNSEVCSFLQYMEKSKPWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDDMPKSADLPHSFKLTQSKSVHSFAADNEELKQKWLKIILLAVTGETPDGPSEHLATLNNLPGPKKKSEC
uniprot
proteins
function
FUNCTION: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates MAPK8 (By similarity). Plays a role in regulating the actin cytoskeleton and cell shape. Promotes the formation of lamellipodia. {ECO:0000250, ECO:0000269|PubMed:10871857, ECO:0000269|PubMed:11527409}.
uniprot
proteins
mass_dalton
86541
uniprot
proteins
pubmed
10871857
uniprot
proteins
pubmed
11527409
uniprot
proteins
pubmed
11952837
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17564959
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
766
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Note=Concentrated in filopodia and poorly detected at lamellipodia. Binds along the sides of actin fibers (By similarity). {ECO:0000250}.
uniprot
proteins