Tnfsf15
entrez
326623
canonical
uniprot
Q5UBV8
canonical
ensembl
ENSMUSG00000050395
resolver
ensp
ENSMUSP00000050144
resolver
ensp
ENSMUSP00000159365
resolver
enst
ENSMUST00000062246
resolver
enst
ENSMUST00000239480
resolver
genesymbol
Tnfsf15
resolver
genesymbol_syn
Tl1
resolver
genesymbol_syn
Tnlg1b
resolver
genesymbol_syn
Vegi
resolver
uniprot
A0A0U5J7F3
resolver
uniprot
A0A6I8MX33
resolver
uniprot
A0ACM8QFR9
resolver
uniprot
B2RR33
resolver
uniprot
E9PVT2
resolver
uniprot
F6VXB8
resolver
uniprot
Q8K3Y8
resolver
uniprot_entry
A0A0U5J7F3_MOUSE
resolver
uniprot_entry
A0A6I8MX33_MOUSE
resolver
uniprot_entry
A0ACM8QFR9_MOUSE
resolver
uniprot_entry
TNF15_MOUSE
resolver
uniprot_sec
B2RR33
resolver
uniprot_sec
E9PVT2
resolver
uniprot_sec
F6VXB8
resolver
uniprot_sec
Q8K3Y8
resolver
amino_acid_sequence
MAEELGLGFGEGVPVEVLPEGCRHRPEARAGLAARSKACLALTCCLLSFPILAGLSTLLMAGQLRVPGKDCMLRAITEERSEPSPQQVYSPPRGKPRAHLTIKKQTPAPHLKNQLSALHWEHDLGMAFTKNGMKYINKSLVIPESGDYFIYSQITFRGTTSVCGDISRGRRPNKPDSITMVITKVADSYPEPARLLTGSKSVCEISNNWFQSLYLGATFSLEEGDRLMVNVSDISLVDYTKEDKTFFGAFLL
uniprot
proteins
function
FUNCTION: Cytokine that signals through TNFRSF25 receptor. Functions as a T-cell costimulator, that increases IL-2 responsiveness and secretion of proinflammatory cytokines which enhances T-cell activation, proliferation and the survival of activated T-cells (PubMed:11911831). Inhibits vascular endothelial growth and angiogenesis (in vitro) (By similarity). {ECO:0000250|UniProtKB:O95150, ECO:0000269|PubMed:11911831}.
uniprot
proteins
mass_dalton
27725
uniprot
proteins
protein_family
Tumor necrosis factor family
uniprot
proteins
pubmed
11911831
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15702971
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
252
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:O95150}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O95150}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins