C0HML8
uniprot
C0HML8
canonical
amino_acid_sequence
MEVTKGQKPTVSATRCRVGVVPAVQGARYCGPEGSGLGAKAALWAQDSFPPTRI
uniprot
proteins
function
FUNCTION: Promotes white adipose tissue browning and enhances adipose tissue plasticity, leading to improved metabolic homeostasis (PubMed:41591734). Acts indirectly on adipocytes through a paracrine mechanism by stimulating IL6 secretion from adipose tissue macrophages (PubMed:41591734). The secreted IL6 induces UCP1 expression in white adipocytes, promoting their conversion to beige adipocytes (PubMed:41591734). {ECO:0000269|PubMed:41591734}.
uniprot
proteins
mass_dalton
5601
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
41591734
uniprot
proteins
sequence_length
54
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:41591734}.
uniprot
proteins