ACTR8
entrez
93973
canonical
uniprot
Q9H981
canonical
ensembl
ENSG00000113812
resolver
ensp
ENSP00000336842
resolver
ensp
ENSP00000419429
resolver
ensp
ENSP00000633915
resolver
ensp
ENSP00000673226
resolver
genesymbol
ACTR8
resolver
genesymbol_syn
ARP8
resolver
genesymbol_syn
INO80N
resolver
hgnc
HGNC:14672
resolver
uniprot
B3KSW7
resolver
uniprot
Q8N566
resolver
uniprot
Q9H663
resolver
uniprot_entry
ARP8_HUMAN
resolver
uniprot_sec
B3KSW7
resolver
uniprot_sec
Q8N566
resolver
uniprot_sec
Q9H663
resolver
amino_acid_sequence
MTQAEKGDTENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIIVIHPGSTTLRIGRATDTLPASIPHVIARRHKQQGQPLYKDSWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEYLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSAQGDGLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW
uniprot
proteins
function
FUNCTION: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.; FUNCTION: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.
uniprot
proteins
mass_dalton
70484
uniprot
proteins
protein_family
ARP8 subfamily
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16230350
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18163988
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18922472
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21303910
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
22977180
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
624
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18163988}. Chromosome {ECO:0000269|PubMed:18163988}. Note=Specifically localizes to mitotic chromosomes.
uniprot
proteins