GPAT2
entrez
150763
canonical
uniprot
Q6NUI2
canonical
ensembl
ENSG00000186281
resolver
ensp
ENSP00000352547
resolver
ensp
ENSP00000389395
resolver
ensp
ENSP00000393770
resolver
ensp
ENSP00000509192
resolver
ensp
ENSP00000532267
resolver
ensp
ENSP00000532268
resolver
ensp
ENSP00000532271
resolver
ensp
ENSP00000532272
resolver
ensp
ENSP00000634210
resolver
ensp
ENSP00000634212
resolver
ensp
ENSP00000634216
resolver
ensp
ENSP00000634218
resolver
ensp
ENSP00000634219
resolver
ensp
ENSP00000713931
resolver
ensp
ENSP00000713932
resolver
ensp
ENSP00000713936
resolver
ensp
ENSP00000713937
resolver
ensp
ENSP00000771245
resolver
enst
ENST00000453542
resolver
enst
ENST00000964153
resolver
enst
ENST00000964159
resolver
genesymbol
GPAT2
resolver
hgnc
HGNC:27168
resolver
uniprot
B4DNZ9
resolver
uniprot
E9PE95
resolver
uniprot
Q6P2E4
resolver
uniprot
Q6ZNI3
resolver
uniprot
Q6ZNI5
resolver
uniprot
Q6ZWJ4
resolver
uniprot_entry
B4DNZ9_HUMAN
resolver
uniprot_entry
E9PE95_HUMAN
resolver
uniprot_entry
GPAT2_HUMAN
resolver
uniprot_sec
Q6P2E4
resolver
uniprot_sec
Q6ZNI3
resolver
uniprot_sec
Q6ZNI5
resolver
uniprot_sec
Q6ZWJ4
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by N-ethylmaleimide (NEM). {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
amino_acid_sequence
MATMLEGRCQTQPRSSPSGREASLWSSGFGMKLEAVTPFLGKYRPFVGRCCQTCTPKSWESLFHRSITDLGFCNVILVKEENTRFRGWLVRRLCYFLWSLEQHIPPCQDVPQKIMESTGVQNLLSGRVPGGTGEGQVPDLVKKEVQRILGHIQAPPRPFLVRLFSWALLRFLNCLFLNVQLHKGQMKMVQKAAQAGLPLVLLSTHKTLLDGILLPFMLLSQGLGVLRVAWDSRACSPALRALLRKLGGLFLPPEASLSLDSSEGLLARAVVQAVIEQLLVSGQPLLIFLEEPPGALGPRLSALGQAWVGFVVQAVQVGIVPDALLVPVAVTYDLVPDAPCDIDHASAPLGLWTGALAVLRSLWSRWGCSHRICSRVHLAQPFSLQEYIVSARSCWGGRQTLEQLLQPIVLGQCTAVPDTEKEQEWTPITGPLLALKEEDQLLVRRLSCHVLSASVGSSAVMSTAIMATLLLFKHQKLLGEFSWLTEEILLRGFDVGFSGQLRSLLQHSLSLLRAHVALLRIRQGDLLVVPQPGPGLTHLAQLSAELLPVFLSEAVGACAVRGLLAGRVPPQGPWELQGILLLSQNELYRQILLLMHLLPQDLLLLKPCQSSYCYCQEVLDRLIQCGLLVAEETPGSRPACDTGRQRLSRKLLWKPSGDFTDSDSDDFGEADGRYFRLSQQSHCPDFFLFLCRLLSPLLKAFAQAAAFLRQGQLPDTELGYTEQLFQFLQATAQEEGIFECADPKLAISAVWTFRDLGVLQQTPSPAGPRLHLSPTFASLDNQEKLEQFIRQFICS
uniprot
proteins
ec_number
2.3.1.15
uniprot
proteins
ec_number
2.3.1.51
uniprot
proteins
function
FUNCTION: Transfers an acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate producing a lysophosphatidic acid (LPA), an essential step for the triacylglycerol (TAG) and glycerophospholipids. In vitro also transfers an acyl-group from acyl-ACP to the LPA producing a phosphatidic acid (PA). Prefers arachidonoyl-CoA as the acyl donor. Required for primary processing step during piRNA biosynthesis. Molecular mechanisms by which it promotes piRNA biosynthesis are unclear and do not involve its acyltransferase activity. {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
mass_dalton
87835
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
protein_family
GPAT/DAPAT family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
795
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q14DK4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
transmembrane_region
TRANSMEM 306..332; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 450..472; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins