SOX15
entrez
6665
canonical
uniprot
O60248
canonical
ensembl
ENSG00000129194
resolver
ensp
ENSP00000355354
resolver
genesymbol
SOX15
resolver
genesymbol_syn
SOX12
resolver
genesymbol_syn
SOX20
resolver
genesymbol_syn
SOX26
resolver
genesymbol_syn
SOX27
resolver
hgnc
HGNC:11196
resolver
uniprot
B4DWU7
resolver
uniprot
D3DTQ0
resolver
uniprot
P35717
resolver
uniprot
Q9Y6W7
resolver
uniprot_entry
SOX15_HUMAN
resolver
uniprot_sec
B4DWU7
resolver
uniprot_sec
D3DTQ0
resolver
uniprot_sec
P35717
resolver
uniprot_sec
Q9Y6W7
resolver
amino_acid_sequence
MALPGSSQDQAWSLEPPAATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKSSGAGPSRCGQGRGNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYLPGSYGSSHCKLEAPSPCSLPQSDPRLQGELLPTYTHYLPPGSPTPYNPPLAGAPMPLTHL
uniprot
proteins
function
FUNCTION: Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence (By similarity). Acts as a transcriptional activator and repressor (By similarity). Binds synergistically with POU5F1 (OCT3/4) to gene promoters (By similarity). Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation (By similarity). Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG (By similarity). Involved in trophoblast giant cell differentiation via enhancement of HAND1 transcriptional activity (By similarity). Regulates transcription of HRC via binding to it proximal enhancer region (By similarity). Involved in skeletal muscle regeneration (By similarity). Also plays a role in the development of myogenic precursor cells (By similarity). {ECO:0000250|UniProtKB:P43267}.
uniprot
proteins
mass_dalton
25251
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
8332506
uniprot
proteins
pubmed
8978787
uniprot
proteins
pubmed
9540826
uniprot
proteins
pubmed
9880678
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
uniprot
proteins