Qtrt2
entrez
106248
canonical
uniprot
B8ZXI1
canonical
ensembl
ENSMUSG00000022704
resolver
ensp
ENSMUSP00000023387
resolver
ensp
ENSMUSP00000158885
resolver
enst
ENSMUST00000023387
resolver
enst
ENSMUST00000239112
resolver
genesymbol
Qtrt2
resolver
genesymbol_syn
QTRT2
resolver
genesymbol_syn
Qtrtd1
resolver
uniprot
A0A5F8MPN7
resolver
uniprot
A9C446
resolver
uniprot
Q5XK35
resolver
uniprot
Z4YJE9
resolver
uniprot_entry
A0A5F8MPN7_MOUSE
resolver
uniprot_entry
QTRT2_MOUSE
resolver
uniprot_entry
Z4YJE9_MOUSE
resolver
uniprot_sec
A9C446
resolver
uniprot_sec
Q5XK35
resolver
amino_acid_sequence
MKLSLIKVVNGCRLGKIQNLGKAGDCTVDIPGCLLYTRTGSAPHLTHQTLRNIHGVPGIAQLTLSSLAEHHEVLAEYKKGVGSFIGMPESLFYCSLHDPVTPGPAGYVTSKSVSVWGFGGRVEMTVSKFMAIQEALQPDWFQCLSDGEASCAETTSIKRARKSVDRSLLFLDSCLRLQEESEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGDPAVTETRLHLLSSVTAELPEDKPRLICGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFTFDCQLNPEETLLQQNGIQEKIKGLDQAKKIEATGCNQEMTSFEINLKEKKYQEDFDPLVRGCSCYCCKNHTRAYIHHLLMTNELLAGVLLMMHNFEHYFGFFCSIREALKNDTLAQLKELICRQMF
uniprot
proteins
function
FUNCTION: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). {ECO:0000255|HAMAP-Rule:MF_03043, ECO:0000269|PubMed:19414587, ECO:0000269|PubMed:35815944}.
uniprot
proteins
mass_dalton
46288
uniprot
proteins
mutagenesis
MUTAGEN 41; /note="S->A: Impaired heterodimerization with QTRT1; when associated with F-354."; /evidence="ECO:0000269|PubMed:35815944"; MUTAGEN 354; /note="Y->F: Impaired heterodimerization with QTRT1; when associated with A-41."; /evidence="ECO:0000269|PubMed:35815944
uniprot
proteins
protein_family
QTRT2 subfamily
uniprot
proteins
protein_family
Queuine tRNA-ribosyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19414587
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
29862811
uniprot
proteins
pubmed
35815944
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03043, ECO:0000269|PubMed:19414587}. Mitochondrion outer membrane {ECO:0000255|HAMAP-Rule:MF_03043, ECO:0000269|PubMed:19414587}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03043, ECO:0000269|PubMed:19414587}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_03043, ECO:0000269|PubMed:19414587}. Note=May associate with the mitochondrion outer membrane. {ECO:0000255|HAMAP-Rule:MF_03043, ECO:0000269|PubMed:19414587}.
uniprot
proteins