CLDN12
entrez
9069
canonical
uniprot
P56749
canonical
ensembl
ENSG00000157224
resolver
ensp
ENSP00000287916
resolver
ensp
ENSP00000378103
resolver
ensp
ENSP00000419053
resolver
ensp
ENSP00000575733
resolver
ensp
ENSP00000575734
resolver
ensp
ENSP00000575735
resolver
ensp
ENSP00000575736
resolver
ensp
ENSP00000575737
resolver
ensp
ENSP00000575738
resolver
ensp
ENSP00000575739
resolver
ensp
ENSP00000575740
resolver
ensp
ENSP00000575741
resolver
ensp
ENSP00000575742
resolver
ensp
ENSP00000575743
resolver
ensp
ENSP00000590377
resolver
ensp
ENSP00000590378
resolver
ensp
ENSP00000590379
resolver
ensp
ENSP00000590380
resolver
ensp
ENSP00000590381
resolver
ensp
ENSP00000590382
resolver
ensp
ENSP00000590383
resolver
ensp
ENSP00000615023
resolver
ensp
ENSP00000615024
resolver
ensp
ENSP00000615025
resolver
ensp
ENSP00000615026
resolver
ensp
ENSP00000615027
resolver
ensp
ENSP00000615028
resolver
ensp
ENSP00000615029
resolver
ensp
ENSP00000615030
resolver
ensp
ENSP00000615031
resolver
ensp
ENSP00000615032
resolver
ensp
ENSP00000615033
resolver
enst
ENST00000287916
resolver
enst
ENST00000394605
resolver
enst
ENST00000496677
resolver
enst
ENST00000905674
resolver
enst
ENST00000905675
resolver
enst
ENST00000905676
resolver
enst
ENST00000905677
resolver
enst
ENST00000905678
resolver
enst
ENST00000905679
resolver
enst
ENST00000905680
resolver
enst
ENST00000905681
resolver
enst
ENST00000905682
resolver
enst
ENST00000905683
resolver
enst
ENST00000905684
resolver
enst
ENST00000920318
resolver
enst
ENST00000920319
resolver
enst
ENST00000920320
resolver
enst
ENST00000920321
resolver
enst
ENST00000920322
resolver
enst
ENST00000920323
resolver
enst
ENST00000920324
resolver
enst
ENST00000944964
resolver
enst
ENST00000944965
resolver
enst
ENST00000944966
resolver
enst
ENST00000944967
resolver
enst
ENST00000944968
resolver
enst
ENST00000944969
resolver
enst
ENST00000944970
resolver
enst
ENST00000944971
resolver
enst
ENST00000944972
resolver
enst
ENST00000944973
resolver
enst
ENST00000944974
resolver
genesymbol
CLDN12
resolver
hgnc
HGNC:2034
resolver
uniprot
B2R687
resolver
uniprot
D6W5Q4
resolver
uniprot
Q7LDZ0
resolver
uniprot_entry
B2R687_HUMAN
resolver
uniprot_entry
CLD12_HUMAN
resolver
uniprot_sec
D6W5Q4
resolver
uniprot_sec
Q7LDZ0
resolver
amino_acid_sequence
MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRNEKNLTVYTGLWVKCARYDGSSDCLMYDTTWYSSVDQLDLRVLQFALPLSMLIAMGALLLCLIGMCNTAFRSSVPNIKLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWVIFYNIHLNKKFEPVFSFDYAVYVTIASAGGLFMTSLILFIWYCTCKSLPSPFWQPLYSHPPSMHTYSQPYSARSRLSAIEIDIPVVSHTT
uniprot
proteins
function
FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. {ECO:0000250}.
uniprot
proteins
mass_dalton
27110
uniprot
proteins
protein_family
Claudin family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20375010
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
244
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, tight junction {ECO:0000250|UniProtKB:Q9ET43}. Cell membrane {ECO:0000269|PubMed:20375010}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 88..108; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 175..195; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins