RIC3
entrez
79608
canonical
uniprot
Q7Z5B4
canonical
ensembl
ENSG00000166405
resolver
ensp
ENSP00000308820
resolver
ensp
ENSP00000333988
resolver
ensp
ENSP00000344904
resolver
ensp
ENSP00000395320
resolver
ensp
ENSP00000431658
resolver
ensp
ENSP00000691056
resolver
ensp
ENSP00000691059
resolver
ensp
ENSP00000691061
resolver
genesymbol
RIC3
resolver
hgnc
HGNC:30338
resolver
uniprot
A0A0S2Z607
resolver
uniprot
A0A0S2Z6D3
resolver
uniprot
B0B1U0
resolver
uniprot
B2RD25
resolver
uniprot
B7Z3Z0
resolver
uniprot
D3DQU5
resolver
uniprot
Q6UX78
resolver
uniprot
Q7Z5B3
resolver
uniprot
Q86T94
resolver
uniprot
Q8TBJ9
resolver
uniprot
Q9HAH8
resolver
uniprot_entry
A0A0S2Z607_HUMAN
resolver
uniprot_entry
A0A0S2Z6D3_HUMAN
resolver
uniprot_entry
B7Z3Z0_HUMAN
resolver
uniprot_entry
RIC3_HUMAN
resolver
uniprot_sec
B0B1U0
resolver
uniprot_sec
B2RD25
resolver
uniprot_sec
D3DQU5
resolver
uniprot_sec
Q6UX78
resolver
uniprot_sec
Q7Z5B3
resolver
uniprot_sec
Q86T94
resolver
uniprot_sec
Q8TBJ9
resolver
uniprot_sec
Q9HAH8
resolver
amino_acid_sequence
MAYSTVQRVALASGLVLALSLLLPKAFLSRGKRQEPPPTPEGKLGRFPPMMHHHQAPSDGQTPGARFQRSHLAEAFAKAKGSGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTTAEDGKCYTAMPGNTHRKITSFELAQLQEKLKETEAAMEKLINRVGPNGESRAQTVTSDQEKRLLHQLREITRVMKEGKFIDRFSPEKEAEEAPYMEDWEGYPEETYPIYDLSDCIKRRQETILVDYPDPKELSAEEIAERMGMIEEEESDHLGWESLPTDPRAQEDNSVTSCDPKPETCSCCFHEDEDPAVLAENAGFSADSYPEQEETTKEEWSQDFKDEGLGISTDKAYTGSMLRKRNPQGLE
uniprot
proteins
function
FUNCTION: Molecular chaperone which facilitates proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) and alpha-8 (CHRNA8) nicotinic acetylcholine receptors (PubMed:12821669, PubMed:15504725, PubMed:16120769, PubMed:18691158, PubMed:32204458). May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:15504725, ECO:0000269|PubMed:15809299, ECO:0000269|PubMed:15927954, ECO:0000269|PubMed:16120769, ECO:0000269|PubMed:17609200, ECO:0000269|PubMed:18691158, ECO:0000269|PubMed:32204458}.
uniprot
proteins
mass_dalton
41092
uniprot
proteins
protein_family
Ric-3 family
uniprot
proteins
pubmed
12821669
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15504725
uniprot
proteins
pubmed
15809299
uniprot
proteins
pubmed
15927954
uniprot
proteins
pubmed
16120769
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17370265
uniprot
proteins
pubmed
17609200
uniprot
proteins
pubmed
17640815
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18691158
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
32204458
uniprot
proteins
sequence_length
369
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 96..116; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins