PRPS1L1
entrez
221823
canonical
uniprot
P21108
canonical
ensembl
ENSG00000229937
resolver
ensp
ENSP00000424595
resolver
enst
ENST00000506618
resolver
genesymbol
PRPS1L1
resolver
genesymbol_syn
PRPS3
resolver
genesymbol_syn
PRPSL
resolver
hgnc
HGNC:9463
resolver
uniprot
Q6P5P6
resolver
uniprot_entry
PRPS3_HUMAN
resolver
uniprot_sec
Q6P5P6
resolver
activity_regulation
ACTIVITY REGULATION: Activated by magnesium and inorganic phosphate. {ECO:0000250|UniProtKB:P60891}.
uniprot
proteins
amino_acid_sequence
MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGEINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAGADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTSIADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAGATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAIRRTHNGESVSYLFSHVPL
uniprot
proteins
ec_number
2.7.6.1
uniprot
proteins
function
FUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. {ECO:0000250|UniProtKB:P60891}.
uniprot
proteins
mass_dalton
34839
uniprot
proteins
pathway_participation
PATHWAY: Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. {ECO:0000250|UniProtKB:P60891}.
uniprot
proteins
protein_family
Ribose-phosphate pyrophosphokinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2168892
uniprot
proteins
sequence_length
318
uniprot
proteins