Lrch1
entrez
380916
canonical
uniprot
P62046
canonical
ensembl
ENSMUSG00000068015
resolver
ensp
ENSMUSP00000086363
resolver
ensp
ENSMUSP00000154004
resolver
ensp
ENSMUSP00000291671
resolver
ensp
ENSMUSP00000291675
resolver
ensp
ENSMUSP00000326909
resolver
enst
ENSMUST00000088970
resolver
enst
ENSMUST00000228252
resolver
genesymbol
Lrch1
resolver
genesymbol_syn
Chdc1
resolver
genesymbol_syn
Kiaa1016
resolver
uniprot
A0A2I3BQ16
resolver
uniprot
E9QLJ4
resolver
uniprot
Q3TU52
resolver
uniprot
Q3UP01
resolver
uniprot_entry
A0A2I3BQ16_MOUSE
resolver
uniprot_entry
LRCH1_MOUSE
resolver
uniprot_entry
Q3TU52_MOUSE
resolver
uniprot_entry
Q3UP01_MOUSE
resolver
uniprot_sec
E9QLJ4
resolver
amino_acid_sequence
MATPGSEPQAFAPALSVTALHPHLHQHHQHHQHHQHHGGTGGTGFNLPLNRGLERALEEAANSGGLNLSARKLKEFPRTTAPGHDLSDTVRADLSKNRLVEVPMELCQFVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQLSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPPELVDLPLVKFDFSCNKVLVIPVCFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTSDSLYLPTIERPHLHQHVEDSKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNAPMSNIVEEDQTIKEDACHRLTPTKGEFQPKPSILGDSGISGQEREQLAGRADARHSGLMNYIKDQAEDCEELLRIEEDAHWHMEELLNSSKDRELDIAMIEQLREAELLQDPNGLSADIIERSILNLFPMDSGEASEFPDPSLNGQLQLETSPDREVQNDLMLQSNGSQYSPNEIRENSPSVSPTANITAPFGLKPRSGSWCPEEVQGSLQAESSPRRPQLLSRHVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVTLHEDLGAALMDGVVLCHLANHVRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEEKLCLPHHILEEKGLVKVGTTVQALLDVTVTKALFT
uniprot
proteins
function
FUNCTION: Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration in response to chemokine stimulation. {ECO:0000269|PubMed:28028151}.
uniprot
proteins
mass_dalton
79076
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28028151
uniprot
proteins
sequence_length
709
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Y2L9}.
uniprot
proteins