Anp32b
entrez
67628
canonical
uniprot
Q9EST5
canonical
ensembl
ENSMUSG00000028333
resolver
ensp
ENSMUSP00000099990
resolver
genesymbol
Anp32b
resolver
genesymbol_syn
Pal31
resolver
uniprot
B1AVH9
resolver
uniprot
Q566J4
resolver
uniprot_entry
AN32B_MOUSE
resolver
uniprot_sec
B1AVH9
resolver
uniprot_sec
Q566J4
resolver
amino_acid_sequence
MDMKRRIHLELRNRTPAAVRELVLDNCKAMDGKIEGLTDEFVNLEFLSLISVGLFSVSDLPKLPKLKKLELSENRIFGGLDRLAEELPSLTHLNLSGNNLKDISTLEPLKRLDCLKSLDLFGCEVTNRSDYRETVFRLLPQLSYLDGYDREDQEAPDSDVEVDSVEEAPDSDGEVDGVDKEEEDEEGEDEEEEEDEDGEEEEDEDEEDEDEDEDVEGEDDEDEVSGEEEEFGHDGEVDEDEEDEDEDEDEEEEESGKGEKRKRETDDEGEDD
uniprot
proteins
function
FUNCTION: Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription (PubMed:21636789). Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis (By similarity). Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes (By similarity). Also plays an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1 (By similarity). Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (PubMed:30890743). {ECO:0000250|UniProtKB:Q92688, ECO:0000269|PubMed:21636789, ECO:0000269|PubMed:30890743}.
uniprot
proteins
mass_dalton
31079
uniprot
proteins
post_translational_modification
PTM: Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group.; PTM: Directly cleaved by caspase-3/CASP3. {ECO:0000250|UniProtKB:Q92688}.
uniprot
proteins
protein_family
ANP32 family
uniprot
proteins
pubmed
11162633
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15895553
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17208939
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19524510
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21636789
uniprot
proteins
pubmed
30890743
uniprot
proteins
pubmed
32231671
uniprot
proteins
sequence_length
272
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q92688}. Note=Accumulates in the nuclei at the S phase. {ECO:0000250|UniProtKB:Q92688}.
uniprot
proteins