Gsn
entrez
227753
canonical
uniprot
P13020
canonical
ensembl
ENSMUSG00000026879
resolver
ensp
ENSMUSP00000028239
resolver
ensp
ENSMUSP00000144561
resolver
ensp
ENSMUSP00000304945
resolver
ensp
ENSMUSP00000326128
resolver
ensp
ENSMUSP00000355704
resolver
genesymbol
Gsn
resolver
genesymbol_syn
Gsb
resolver
uniprot
Q3UPB1
resolver
uniprot
Q6PAC1
resolver
uniprot
Q8R590
resolver
uniprot_entry
GELS_MOUSE
resolver
uniprot_entry
Q6PAC1_MOUSE
resolver
uniprot_sec
Q3UPB1
resolver
uniprot_sec
Q8R590
resolver
amino_acid_sequence
MAPYRSSLLCALLLLALCALSPSHAATTSRGRAQERAPQSRVSEARPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGGEPEAMLQVLGPKPALPEGTEDTAKEDAANRRLAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLGYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTAPASIRLFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLKVLRSQHVQVEEGSEPDAFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDNYWSVDPLDRALAELAA
uniprot
proteins
function
FUNCTION: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (By similarity). Plays a role in ciliogenesis (By similarity). {ECO:0000250|UniProtKB:P06396}.
uniprot
proteins
mass_dalton
85942
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues in vitro. {ECO:0000250}.
uniprot
proteins
protein_family
Villin/gelsolin family
uniprot
proteins
pubmed
12742020
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22633459
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24743229
uniprot
proteins
pubmed
2546951
uniprot
proteins
pubmed
28695858
uniprot
proteins
pubmed
31199804
uniprot
proteins
pubmed
37126682
uniprot
proteins
pubmed
7523108
uniprot
proteins
sequence_length
780
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytoskeleton.; SUBCELLULAR LOCATION: [Isoform 1]: Secreted.
uniprot
proteins