Inhibition of host interferon receptors by virus
uniprot_keyword
KW-1091
canonical
name
Inhibition of host interferon receptors by virus
uniprot
definition
Viral protein involved in the evasion of the interferon pathway by inhibiting interferon receptors. Interferon signaling exerts antiviral effects through cell surface receptors termed interferon receptors. In response to binding of extracellular interferons, they activate the JAK/STAT pathway causing transcriptional activation of IFN-regulated genes. To avoid this antiviral response, several viruses target the interferon receptors and send them to degradation via the proteasome.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
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uniprot
keywords