COA1
entrez
55744
canonical
uniprot
Q9GZY4
canonical
ensembl
ENSG00000106603
resolver
ensp
ENSP00000223336
resolver
ensp
ENSP00000312100
resolver
ensp
ENSP00000379218
resolver
ensp
ENSP00000387433
resolver
ensp
ENSP00000395586
resolver
ensp
ENSP00000400759
resolver
ensp
ENSP00000410365
resolver
ensp
ENSP00000413777
resolver
ensp
ENSP00000416406
resolver
ensp
ENSP00000567033
resolver
ensp
ENSP00000567034
resolver
ensp
ENSP00000567035
resolver
ensp
ENSP00000567036
resolver
ensp
ENSP00000567037
resolver
ensp
ENSP00000567038
resolver
ensp
ENSP00000567040
resolver
ensp
ENSP00000567041
resolver
ensp
ENSP00000567042
resolver
ensp
ENSP00000567043
resolver
ensp
ENSP00000567044
resolver
ensp
ENSP00000567045
resolver
ensp
ENSP00000567046
resolver
ensp
ENSP00000567047
resolver
ensp
ENSP00000567048
resolver
ensp
ENSP00000567049
resolver
ensp
ENSP00000567050
resolver
ensp
ENSP00000567051
resolver
ensp
ENSP00000567052
resolver
ensp
ENSP00000567053
resolver
ensp
ENSP00000567054
resolver
ensp
ENSP00000567055
resolver
ensp
ENSP00000567056
resolver
ensp
ENSP00000567057
resolver
ensp
ENSP00000567058
resolver
ensp
ENSP00000567059
resolver
ensp
ENSP00000567060
resolver
ensp
ENSP00000567061
resolver
ensp
ENSP00000604929
resolver
ensp
ENSP00000604930
resolver
ensp
ENSP00000604931
resolver
ensp
ENSP00000604932
resolver
ensp
ENSP00000604936
resolver
ensp
ENSP00000604940
resolver
ensp
ENSP00000604941
resolver
ensp
ENSP00000604942
resolver
ensp
ENSP00000604943
resolver
ensp
ENSP00000604944
resolver
ensp
ENSP00000604945
resolver
ensp
ENSP00000604946
resolver
ensp
ENSP00000604947
resolver
ensp
ENSP00000619497
resolver
ensp
ENSP00000619498
resolver
ensp
ENSP00000619499
resolver
ensp
ENSP00000619500
resolver
ensp
ENSP00000619501
resolver
ensp
ENSP00000619502
resolver
ensp
ENSP00000619503
resolver
enst
ENST00000223336
resolver
enst
ENST00000310564
resolver
enst
ENST00000395879
resolver
enst
ENST00000415076
resolver
enst
ENST00000418140
resolver
enst
ENST00000438444
resolver
enst
ENST00000446330
resolver
enst
ENST00000446564
resolver
enst
ENST00000457939
resolver
enst
ENST00000896974
resolver
enst
ENST00000896975
resolver
enst
ENST00000896976
resolver
enst
ENST00000896977
resolver
enst
ENST00000896978
resolver
enst
ENST00000896979
resolver
enst
ENST00000896981
resolver
enst
ENST00000896982
resolver
enst
ENST00000896983
resolver
enst
ENST00000896984
resolver
enst
ENST00000896985
resolver
enst
ENST00000896986
resolver
enst
ENST00000896987
resolver
enst
ENST00000896988
resolver
enst
ENST00000896989
resolver
enst
ENST00000896990
resolver
enst
ENST00000896991
resolver
enst
ENST00000896992
resolver
enst
ENST00000896993
resolver
enst
ENST00000896994
resolver
enst
ENST00000896995
resolver
enst
ENST00000896996
resolver
enst
ENST00000896997
resolver
enst
ENST00000896998
resolver
enst
ENST00000896999
resolver
enst
ENST00000897000
resolver
enst
ENST00000897001
resolver
enst
ENST00000897002
resolver
enst
ENST00000934870
resolver
enst
ENST00000934871
resolver
enst
ENST00000934872
resolver
enst
ENST00000934873
resolver
enst
ENST00000934877
resolver
enst
ENST00000934881
resolver
enst
ENST00000934882
resolver
enst
ENST00000934883
resolver
enst
ENST00000934884
resolver
enst
ENST00000934885
resolver
enst
ENST00000934886
resolver
enst
ENST00000934887
resolver
enst
ENST00000934888
resolver
enst
ENST00000949438
resolver
enst
ENST00000949439
resolver
enst
ENST00000949440
resolver
enst
ENST00000949441
resolver
enst
ENST00000949442
resolver
enst
ENST00000949443
resolver
enst
ENST00000949444
resolver
genesymbol
COA1
resolver
genesymbol_syn
C7orf44
resolver
genesymbol_syn
MITRAC15
resolver
hgnc
HGNC:21868
resolver
uniprot
A6NJU8
resolver
uniprot
A8KAH8
resolver
uniprot
F2Z2J3
resolver
uniprot
Q9HAB7
resolver
uniprot
Q9NVD2
resolver
uniprot_entry
COA1_HUMAN
resolver
uniprot_entry
F2Z2J3_HUMAN
resolver
uniprot_sec
A6NJU8
resolver
uniprot_sec
A8KAH8
resolver
uniprot_sec
Q9HAB7
resolver
uniprot_sec
Q9NVD2
resolver
amino_acid_sequence
MMWQKYAGSRRSMPLGARILFHGVFYAGGFAIVYYLIQKFHSRALYYKLAVEQLQSHPEAQEALGPPLNIHYLKLIDRENFVDIVDAKLKIPVSGSKSEGLLYVHSSRGGPFQRWHLDEVFLELKDGQQIPVFKLSGENGDEVKKE
uniprot
proteins
function
FUNCTION: Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV (PubMed:23260140). As part of the MCIA complex, required for efficient assembly of the mitochondrial complex I (PubMed:32320651). {ECO:0000269|PubMed:23260140, ECO:0000269|PubMed:32320651}.
uniprot
proteins
mass_dalton
16694
uniprot
proteins
protein_family
COA1 family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22356826
uniprot
proteins
pubmed
23260140
uniprot
proteins
pubmed
32320651
uniprot
proteins
sequence_length
146
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:22356826, ECO:0000269|PubMed:23260140}; Single-pass membrane protein {ECO:0000269|PubMed:22356826, ECO:0000269|PubMed:23260140}.
uniprot
proteins
transmembrane_region
TRANSMEM 15..37; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins