Fam193a
entrez
231128
canonical
uniprot
Q8CGI1
canonical
ensembl
ENSMUSG00000037210
resolver
ensp
ENSMUSP00000092463
resolver
ensp
ENSMUSP00000138082
resolver
enst
ENSMUST00000094867
resolver
genesymbol
Fam193a
resolver
uniprot
M0QWZ1
resolver
uniprot
Q499G1
resolver
uniprot_entry
F193A_MOUSE
resolver
uniprot_sec
M0QWZ1
resolver
uniprot_sec
Q499G1
resolver
amino_acid_sequence
MSPADAKRGAKRRKNKRGGGGGSGGGGSGGKAGSAAALRGPQAPGPGAAGLLGGAAAHGPLGAGAGGAAGGYFETPFSFGMNHRTPPYPAGDYCLLCRSERKDSSFLESGVKTASKLALSMAPKGNSVLHLPLWVCPDCRRTVEKEERHSGLDQPGQDFLLHSSLGGSQPETSGAGRLALGTQTMTSSGLGTTPSDACSCEACSERRDISAETEREPQQLQNYWSEVRYMVRCIYRQAGTPLAEDQDQSLVPDKEGVKELVDRLCERDPYQLYQRLEQQAREYVLEMKVRLLRQLSAAAKAKAPSGLQGPPQAHHFVSLLLEEYAALCQAARSISTFLGTLENEHLKKFQVTWELHNKHLFENLVFSEPLLQSNLPALVSQIRLGTTTHDTCTEDMYSTLLQRYQRSEEELRKVAEEWLECQKRIDAYVDEQMTMKTKQRMLTEDWEIFKQRRLIEEQLTNKKVVTGENNFTDTRRHMLSSRLSMPDCPNCNYRRRCACDDCSLSHILTCGIMDTPVTDDIHIHQLPLQVDSAPDYLSEMRPPSVSSASSGSGSSSPITIQQHPRLILTDNGSAPTFCSDDEDVAPLSAKFADIYPLTNYDDTNVVANMNGIHSELNGGGENMALKDESPQVSSTSRSSSEADDEDADGESSGEPPGAPKQEEAIGNGNPKTEESNVNTPPPSYPAQQAEQTPNTCECHVCKQEASGLPASAMTAGALPPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYPAPPFTHSKALPPAPVQSHTNKPQAFNASLQDHIYPSCFGNTPDWNSSKFISLWESEMMNDKNWNPGTFLPDTISGNDILGPVLSETRPEALPPPPSNEAPAVSDIKEKKNAAKKKCLYNFQDAFMEANEVAMANTVAMATSSATSSVSCTATTVQSSSSQFKVSSRRPPSIGDVFHGLNKEDHRHSAPAAPRNSPTGLAPLPALSPSALSPASTPHLPNLAAPSFPKTATTAPGFVDTRKSFCPTPVAPPPSTTDGSISAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHSSSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMEQISEREGVVDHRRVEDLLQFINSSEAKPVSSSRAAKRARHKQRKLEEKARLEAEARAREHLHHQEEQKQREEEEDEEEEDEEQHFKEEFQRLQELQKLRAAKKKKKDRPSKDCSKLDMLARNFQAATESISNSENIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGPGANGDATDPVDPRDPSKLLLPKEVNGKQHEPLAFLLDMMHHHKEGNSKQKLKQTSKTSNEPARKPTEPPKTTEVQLKPRAQPELKPKVVDLALLTEQKREERKTNSNNNNKKQLSHIKEEKLSTVTPEPPSPSQLLQNGRLILASSPQPKGKNKKNKKKKGDRTSSSLDDVFLPKDIDLDSVDMDETEREVEYFKRFCLDSARQNRQRLSINWSNFSLKKATFAAH
uniprot
proteins
function
FUNCTION: Acts as a positive regulator of p53/TP53 by interacting with p53 repressors MDM2 and MDM4 and destabilizing MDM4 which leads to enhanced p53 transcriptional activity. {ECO:0000250|UniProtKB:P78312}.
uniprot
proteins
mass_dalton
166901
uniprot
proteins
protein_family
FAM193 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1517
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P78312}. Cytoplasm {ECO:0000250|UniProtKB:P78312}. Note=Localization is heterogeneous from cell to cell, ranging from mostly cytoplasmic to almost exclusively nuclear. {ECO:0000250|UniProtKB:P78312}.
uniprot
proteins