Cmbl
entrez
69574
canonical
uniprot
Q8R1G2
canonical
ensembl
ENSMUSG00000022235
resolver
ensp
ENSMUSP00000070314
resolver
ensp
ENSMUSP00000153812
resolver
ensp
ENSMUSP00000256700
resolver
ensp
ENSMUSP00000256705
resolver
ensp
ENSMUSP00000256712
resolver
enst
ENSMUST00000070918
resolver
genesymbol
Cmbl
resolver
uniprot
Q8C1N1
resolver
uniprot_entry
CMBL_MOUSE
resolver
uniprot_sec
Q8C1N1
resolver
activity_regulation
ACTIVITY REGULATION: Strongly inhibited by p-chloromercuribenzoate (PCMB). Partially inhibited by bis-p-nitrophenylphosphate (BNPP). Not inhibited by DFP, PMSF, eserine or EDTA. {ECO:0000250|UniProtKB:Q96DG6}.
uniprot
proteins
amino_acid_sequence
MANEANPCPCDIGHKLEYGGMGHEVQVEHIKAYVTRSPVDAGKAVIVVQDIFGWQLPNTRYMADMIARNGYTTIVPDFFVGQEPWDPAGDWSTFPAWLKSRNARKVNREVDAVLRYLRQQCHAQKIGIVGFCWGGVVVHQVMTAYPDIRAGVSVYGIIRDSEDVYNLKNPTLFIFAENDTVIPLEQVSTLTQKLKEHCIVNYQVKTFSGQTHGFVHRKREDCSPADKPYIEEARRNLIEWLNKYV
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Cysteine hydrolase whose endogenous substrates and physiological function are unknown. In vitro, catalyzes the hydrolytic activation of several ester-based prodrugs, by cleaving the dioxolone ring to yield their respective active metabolites, diacetyl and CO2. {ECO:0000250|UniProtKB:Q96DG6}.
uniprot
proteins
mass_dalton
27902
uniprot
proteins
protein_family
Dienelactone hydrolase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
245
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q96DG6}.
uniprot
proteins