LRRTM2
entrez
26045
canonical
uniprot
O43300
canonical
ensembl
ENSG00000146006
resolver
ensp
ENSP00000274711
resolver
enst
ENST00000274711
resolver
genesymbol
LRRTM2
resolver
genesymbol_syn
KIAA0416
resolver
genesymbol_syn
LRRN2
resolver
hgnc
HGNC:19409
resolver
uniprot
A0AVL3
resolver
uniprot
A8K4U9
resolver
uniprot
B7ZLN8
resolver
uniprot
Q7L770
resolver
uniprot_entry
LRRT2_HUMAN
resolver
uniprot_sec
A0AVL3
resolver
uniprot_sec
A8K4U9
resolver
uniprot_sec
B7ZLN8
resolver
uniprot_sec
Q7L770
resolver
amino_acid_sequence
MGLHFKWPLGAPMLAAIYAMSMVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTVMATTYRDPTTEYTKRISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMVQNHRQLRSQTRLHMSNMSDQGPYNEYEPTHEGPFIIINGYGQCKCQQLPYKECEV
uniprot
proteins
function
FUNCTION: Involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity). {ECO:0000250|UniProtKB:D4A7P2}.
uniprot
proteins
mass_dalton
59076
uniprot
proteins
protein_family
LRRTM family
uniprot
proteins
pubmed
12676565
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9455477
uniprot
proteins
sequence_length
516
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Localized to excitatory synapses. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 423..443; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins