Kyat3
entrez
541589
canonical
uniprot
Q58FK9
canonical
ensembl
ENSRNOG00000043426
resolver
ensp
ENSRNOP00000083094
resolver
ensp
ENSRNOP00000103048
resolver
ensp
ENSRNOP00000108974
resolver
enst
ENSRNOT00000101068
resolver
enst
ENSRNOT00000149481
resolver
enst
ENSRNOT00000153006
resolver
genesymbol
Kyat3
resolver
genesymbol_syn
Ccbl2
resolver
genesymbol_syn
Kat3
resolver
uniprot
A0A8I5ZUT0
resolver
uniprot
A0ABK0LM67
resolver
uniprot
A0ABK0LUF7
resolver
uniprot_entry
A0A8I5ZUT0_RAT
resolver
uniprot_entry
A0ABK0LM67_RAT
resolver
uniprot_entry
A0ABK0LUF7_RAT
resolver
uniprot_entry
KAT3_RAT
resolver
amino_acid_sequence
MLLAQRRLFSLGCRAKPIKTIYSSKVLGLSTSAKMALRFKNAKRIEGLDQNVWVEFTKLAADPSVVNLGQGFPDITLPSYVQEELSKAAFIDNLNQYTRGFGHPSLVKALSCLYGKIYQKQIDPNEEILVTVGGYGSLFNAIQGLVDPGDEVIIMVPFYDCYEPMVKMAGAVPVFIPLRSKRTDGMKWTSSDWTFNPQELESKFSSKTKAIILNTPHNPIGKVYTREELQVIADLCIKHDTLCISDEVYEWLVYTGHKHIKVASLPGMWDRTLTIGSAGKTFSVTGWKLGWSIGPGHLIKHLRTVQQTSVYTCATPLQAALAEAFWIDIKRMDDPECYFNSLPKELEVKRDRMACLLNSVGLKPIIPDGGYFIIADVSSLGVDLSDVKSDEPYDYKFVKWMTKNKKLSAIPVSAFCDSESKPHFEKLVRFCFIKKDSTLDAAEEIFRTWNSRKS
uniprot
proteins
ec_number
2.6.1.63
uniprot
proteins
ec_number
2.6.1.7
uniprot
proteins
ec_number
4.4.1.13
uniprot
proteins
function
FUNCTION: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro). {ECO:0000250|UniProtKB:Q71RI9}.
uniprot
proteins
mass_dalton
51044
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-kynurenine degradation; kynurenate from L-kynurenine: step 1/2. {ECO:0000250|UniProtKB:Q71RI9}.
uniprot
proteins
protein_family
Class-I pyridoxal-phosphate-dependent aminotransferase family
uniprot
proteins
pubmed
16376499
uniprot
proteins
sequence_length
454
uniprot
proteins