FXYD4
entrez
53828
canonical
uniprot
P59646
canonical
ensembl
ENSG00000150201
resolver
ensp
ENSP00000473361
resolver
ensp
ENSP00000483791
resolver
ensp
ENSP00000533589
resolver
ensp
ENSP00000533590
resolver
ensp
ENSP00000533591
resolver
ensp
ENSP00000533593
resolver
enst
ENST00000476166
resolver
enst
ENST00000616495
resolver
enst
ENST00000863530
resolver
enst
ENST00000863531
resolver
enst
ENST00000863532
resolver
enst
ENST00000863534
resolver
genesymbol
FXYD4
resolver
hgnc
HGNC:4028
resolver
uniprot
Q6UWZ1
resolver
uniprot
Q7Z4M5
resolver
uniprot_entry
FXYD4_HUMAN
resolver
uniprot_sec
Q6UWZ1
resolver
uniprot_sec
Q7Z4M5
resolver
amino_acid_sequence
MERVTLALLLLAGLTALEANDPFANKDDPFYYDWKNLQLSGLICGGLLAIAGIAAVLSGKCKCKSSQKQHSPVPEKAIPLITPGSATTC
uniprot
proteins
function
FUNCTION: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (By similarity). Increases the apparent affinity of the transporter for Na(+) and increases NKA activity (By similarity). {ECO:0000250|UniProtKB:Q63113}.
uniprot
proteins
mass_dalton
9373
uniprot
proteins
protein_family
FXYD family
uniprot
proteins
pubmed
10950925
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
89
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q63113}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63113}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q63113}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63113}. Note=Detected in the basolateral membrane of collecting duct principal cells. {ECO:0000250|UniProtKB:Q63113}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q63113
uniprot
proteins