MED7
entrez
9443
canonical
uniprot
O43513
canonical
ensembl
ENSG00000155868
resolver
ensp
ENSP00000286317
resolver
ensp
ENSP00000401046
resolver
ensp
ENSP00000599792
resolver
enst
ENST00000286317
resolver
enst
ENST00000420343
resolver
enst
ENST00000929733
resolver
genesymbol
CRSP9
resolver
genesymbol
MED7
resolver
genesymbol_syn
ARC34
resolver
genesymbol_syn
CRSP9
resolver
hgnc
HGNC:2378
resolver
uniprot
Q6IAZ5
resolver
uniprot_entry
MED7_HUMAN
resolver
uniprot_entry
Q6IAZ5_HUMAN
resolver
amino_acid_sequence
MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKTEPMDADDSNNCTGQNEHQRENSGHRRDQIIEKDAALCVLIDEMNERP
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
uniprot
proteins
mass_dalton
27245
uniprot
proteins
post_translational_modification
PTM: Constitutively sumoylated. {ECO:0000269|PubMed:17709345}.
uniprot
proteins
protein_family
Mediator complex subunit 7 family
uniprot
proteins
pubmed
10235267
uniprot
proteins
pubmed
15175163
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15989967
uniprot
proteins
pubmed
17709345
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
25114211
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
25772364
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
9671713
uniprot
proteins
pubmed
9989412
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins