Slc6a7
entrez
240332
canonical
uniprot
Q6PGE7
canonical
ensembl
ENSMUSG00000052026
resolver
ensp
ENSMUSP00000025520
resolver
enst
ENSMUST00000025520
resolver
genesymbol
Slc6a7
resolver
uniprot
Q80UM1
resolver
uniprot_entry
SC6A7_MOUSE
resolver
uniprot_sec
Q80UM1
resolver
amino_acid_sequence
MKKLQEAHLRKPITPDLLMTPSDQGDVDLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCGNWWNTELCLEHRGPKSGNGVLPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEEESMM
uniprot
proteins
function
FUNCTION: Brain specific sodium (and chloride)-dependent proline transporter. Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals. {ECO:0000250|UniProtKB:P28573}.
uniprot
proteins
mass_dalton
71066
uniprot
proteins
protein_family
SLC6A7 subfamily
uniprot
proteins
protein_family
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
637
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Synaptic cell membrane {ECO:0000250|UniProtKB:Q99884}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 46..66; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 74..93; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 215..233; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 242..259; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 295..312; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 324..345; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 378..397; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 425..443; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 459..479; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 500..519; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 538..556; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins