Rnh1
entrez
107702
canonical
uniprot
Q91VI7
canonical
ensembl
ENSMUSG00000038650
resolver
ensp
ENSMUSP00000101651
resolver
ensp
ENSMUSP00000133061
resolver
ensp
ENSMUSP00000147928
resolver
enst
ENSMUST00000106033
resolver
enst
ENSMUST00000167493
resolver
enst
ENSMUST00000210314
resolver
genesymbol
Rnh1
resolver
genesymbol_syn
Rnh
resolver
uniprot
A0A1B0GSG5
resolver
uniprot
Q924P4
resolver
uniprot_entry
A0A1B0GSG5_MOUSE
resolver
uniprot_entry
RINI_MOUSE
resolver
uniprot_sec
Q924P4
resolver
amino_acid_sequence
MSLDIQCEQLSDARWTELLPLIQQYEVVRLDDCGLTEVRCKDISSAVQANPALTELSLRTNELGDGGVGLVLQGLQNPTCKIQKLSLQNCGLTEAGCGILPGMLRSLSTLRELHLNDNPMGDAGLKLLCEGLQDPQCRLEKLQLEYCNLTATSCEPLASVLRVKADFKELVLSNNDLHEPGVRILCQGLKDSACQLESLKLENCGITAANCKDLCDVVASKASLQELDLSSNKLGNAGIAALCPGLLLPSCKLRTLWLWECDITAEGCKDLCRVLRAKQSLKELSLASNELKDEGARLLCESLLEPGCQLESLWIKTCSLTAASCPYFCSVLTKSRSLLELQMSSNPLGDEGVQELCKALSQPDTVLRELWLGDCDVTNSGCSSLANVLLANRSLRELDLSNNCMGGPGVLQLLESLKQPSCTLQQLVLYDIYWTNEVEEQLRALEEERPSLRIIS
uniprot
proteins
function
FUNCTION: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress. Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus. {ECO:0000250|UniProtKB:P13489}.
uniprot
proteins
mass_dalton
49816
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
456
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P13489}. Nucleus {ECO:0000250|UniProtKB:P13489}. Note=Localizes in the cytoplasm in absence of stress; translocates to the nucleus in response to stress. {ECO:0000250|UniProtKB:P13489}.
uniprot
proteins