Amigo2
entrez
300186
canonical
uniprot
Q7TNJ4
canonical
ensembl
ENSRNOG00000007032
resolver
ensp
ENSRNOP00000009199
resolver
ensp
ENSRNOP00000085327
resolver
enst
ENSRNOT00000009199
resolver
enst
ENSRNOT00000097759
resolver
genesymbol
Amigo2
resolver
genesymbol_syn
Ali1
resolver
uniprot
A0A0G2JSI9
resolver
uniprot
Q80ZD6
resolver
uniprot_entry
A0A0G2JSI9_RAT
resolver
uniprot_entry
AMGO2_RAT
resolver
uniprot_sec
Q80ZD6
resolver
amino_acid_sequence
MSLRFHTLPTLPRAVKPGCRELLCLLVIAVMVSPSSSGLCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDADWIPVSFVKLSTLIVRHNNITSISTGSFSTTPNLKCLDLSSNRLKSVKSAMFQELKVLEVLLLYNNHISYLDPAAFGGLSHLQKLYLSGNFLTKFPMDLYVGRFKLADLTFLDVSYNQIASIPMHHINLVPGKQLRGIFLHGNPFVCDCSLYSLLTFWYRRHFNSVTDFKHDYTCRLWLDSRHSHQLLLLQDSFLNCSHSVINGSFHALGFIHEAQVGERAIVHCDGKTGNGNTDFIWVGPDNRLLEPDKDTGNFRVFYNGSLVIENPGFEDAGVYSCIAMNRQRLLNETVDIMINVSNFTINRSHHAHEAFNTAFTTLAACVVSIVLVLLYLYLTPCPCKCRDKRQKNALNQSNAHSSILSPGPTRDASAEDRKAGKRVVFLEPLKDPAVGQNGKVKLVPSKTVIAEGILKSSRAKSDSDSVNSVFSDTPFVAST
uniprot
proteins
function
FUNCTION: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. {ECO:0000269|PubMed:12629050, ECO:0000269|PubMed:12843293}.
uniprot
proteins
mass_dalton
57759
uniprot
proteins
protein_family
AMIGO family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12629050
uniprot
proteins
pubmed
12843293
uniprot
proteins
sequence_length
520
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Nucleus {ECO:0000269|PubMed:12843293}. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.
uniprot
proteins
transmembrane_region
TRANSMEM 399..419; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins