GP5
entrez
2814
canonical
uniprot
P40197
canonical
ensembl
ENSG00000178732
resolver
ensp
ENSP00000383931
resolver
ensp
ENSP00000509337
resolver
enst
ENST00000401815
resolver
enst
ENST00000692618
resolver
genesymbol
GP5
resolver
hgnc
HGNC:4443
resolver
uniprot
D1MER9
resolver
uniprot_entry
GPV_HUMAN
resolver
uniprot_sec
D1MER9
resolver
amino_acid_sequence
MLRGTLLCAVLGLLRAQPFPCPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAECPGPRGPPPRPAADSSSEAPVHPALAPNSSEPWVWAQPVTTGKGQDHSPFWGFYFLLLAVQAMITVIIVFAMIKIGQLFRKLIRERALG
uniprot
proteins
function
FUNCTION: The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
uniprot
proteins
mass_dalton
60959
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
pubmed
16263699
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
2350580
uniprot
proteins
pubmed
2372284
uniprot
proteins
pubmed
7690959
uniprot
proteins
pubmed
8407908
uniprot
proteins
sequence_length
560
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 524..544; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins