FOSL2
entrez
2355
canonical
uniprot
P15408
canonical
ensembl
ENSG00000075426
resolver
ensp
ENSP00000264716
resolver
ensp
ENSP00000368939
resolver
ensp
ENSP00000572852
resolver
ensp
ENSP00000796949
resolver
genesymbol
FOSL2
resolver
genesymbol_syn
FRA2
resolver
hgnc
HGNC:3798
resolver
uniprot
B2RD58
resolver
uniprot
B3KP27
resolver
uniprot
B4DYV4
resolver
uniprot
Q6FG46
resolver
uniprot
Q9H5M2
resolver
uniprot_entry
FOSL2_HUMAN
resolver
uniprot_entry
Q9H5M2_HUMAN
resolver
uniprot_sec
B2RD58
resolver
uniprot_sec
B3KP27
resolver
uniprot_sec
B4DYV4
resolver
uniprot_sec
Q6FG46
resolver
amino_acid_sequence
MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL
uniprot
proteins
disease_involvement
DISEASE: Aplasia cutis-enamel dysplasia (ACED) [MIM:620789]: An autosomal dominant disorder characterized by congenital absence of a portion of skin of the scalp with or without skull defects, enamel hypoplasia, and neurodevelopmental delay with autism spectrum disorder. {ECO:0000269|PubMed:36197437}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Controls osteoclast survival and size (By similarity). As a dimer with JUN, activates LIF transcription (By similarity). Activates CEBPB transcription in PGE2-activated osteoblasts (By similarity). {ECO:0000250|UniProtKB:P47930, ECO:0000250|UniProtKB:P51145}.
uniprot
proteins
mass_dalton
35193
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
protein_family
Fos subfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
2107490
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25114211
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
25772364
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
36197437
uniprot
proteins
sequence_length
326
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P51145}.
uniprot
proteins