ARK2N
entrez
147339
canonical
uniprot
Q96B23
canonical
ensembl
ENSG00000152242
resolver
ensp
ENSP00000480074
resolver
ensp
ENSP00000481626
resolver
ensp
ENSP00000585866
resolver
genesymbol
ARK2N
resolver
genesymbol_syn
ARKL1
resolver
genesymbol_syn
C18orf25
resolver
hgnc
HGNC:28172
resolver
uniprot
A8K123
resolver
uniprot
A8KAB6
resolver
uniprot
Q5BIX2
resolver
uniprot
Q5XG78
resolver
uniprot
Q6N058
resolver
uniprot
Q86TB5
resolver
uniprot
Q8TCQ5
resolver
uniprot_entry
ARK2N_HUMAN
resolver
uniprot_sec
A8K123
resolver
uniprot_sec
A8KAB6
resolver
uniprot_sec
Q5BIX2
resolver
uniprot_sec
Q5XG78
resolver
uniprot_sec
Q6N058
resolver
uniprot_sec
Q86TB5
resolver
uniprot_sec
Q8TCQ5
resolver
amino_acid_sequence
MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL
uniprot
proteins
function
FUNCTION: AMPK substrate important for exercise capacity and skeletal muscle function. Required for normal contraction-induced signaling. {ECO:0000269|PubMed:35882232}.; FUNCTION: (Microbial infection) Upon Epstein-Barr virus (EBV) infection, suppresses viral BZLF1 expression and subsequent EBV reactivation by interacting with JUN and inhibiting its transcriptional activator activity on BZLF1 Z promoter. {ECO:0000269|PubMed:31341047}.
uniprot
proteins
mass_dalton
43395
uniprot
proteins
mutagenesis
MUTAGEN 66..67; /note="SS->AA: Loss of phosphorylation by AMPK. Decreases muscle specific force."; /evidence="ECO:0000269|PubMed:35882232"; MUTAGEN 66..67; /note="SS->DD: Increased phosphorylation. Increases muscle specific force."; /evidence="ECO:0000269|PubMed:35882232
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at Ser-67 by AMPK. In skeletal muscle, phosphorylation is induced by exercise and seems to increase muscle contractile function. {ECO:0000269|PubMed:35882232}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15722956
uniprot
proteins
pubmed
16177791
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24216761
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
31341047
uniprot
proteins
pubmed
35882232
uniprot
proteins
sequence_length
404
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:31341047}.
uniprot
proteins