Asb14
entrez
142687
canonical
uniprot
Q8C6Y6
canonical
ensembl
ENSMUSG00000021898
resolver
ensp
ENSMUSP00000159012
resolver
ensp
ENSMUSP00000159151
resolver
enst
ENSMUST00000238987
resolver
enst
ENSMUST00000239004
resolver
genesymbol
Asb14
resolver
uniprot
A0A5F8MPK4
resolver
uniprot
A0A5F8MPW7
resolver
uniprot
B7ZN45
resolver
uniprot
Q8VHS7
resolver
uniprot_entry
A0A5F8MPK4_MOUSE
resolver
uniprot_entry
A0A5F8MPW7_MOUSE
resolver
uniprot_entry
ASB14_MOUSE
resolver
uniprot_sec
B7ZN45
resolver
uniprot_sec
Q8VHS7
resolver
amino_acid_sequence
MDPSGSDEDADADFDTQVIIQQSLLDVYKPGIAQHTPEAARLHSFPSDDYKKIAEAIETGKEDALAGFAKYHPAFDEANGNGWLPLHKAAVQLNKNILEITMNASEPSTWERTTHNGETALFLAVSSSLLENAHFLLLKGCNPNAKTSEGNSPLLTAVLKDAYDMATLLISHGADVNLRCANERTALHEAAKLGRLDMVKLMLASGAYPDARSSYGFTPLALAAQGGHTGIMQLLLQKGADVHSQASDSSSVLLEAVRGGNPEAVSLLLEYGADANIPKSSGHLPIHVAADKGHFLALKVLVPVTDIAAIKKSGISPVHCAAAGAHPHCLELLIQAGFDVNFMLDQRIRKHYDDQRKSALYFAVSNGDLPSVKLLLSAGALPNQDPVNCLQIALRMGNYELISLLLRHGANVNYFCRVNPLHFPSALQYTLKDEVMLRMLLNYGYDTERCFDCPHGERVHRFCTFEGWTSTVIKDTMFCEVITLSWLQHLSGKVVRVMLDYVDQVQICSKLKAVLEKQRLWPEIHFILANPRSLQHLCRLKIRKCMGRLRLRCPVFMSFLPLPNLLKAYVLYKEYDLFGQERSTGTW
uniprot
proteins
function
FUNCTION: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Plays a role in the inhibition of cardiomyocyte nuclear proliferation by mediating the ubiquitination and degradation of MAPRE2 (PubMed:38319584). {ECO:0000269|PubMed:38319584}.
uniprot
proteins
mass_dalton
64883
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
protein_family
Ankyrin SOCS box (ASB) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
38319584
uniprot
proteins
sequence_length
587
uniprot
proteins