Viral penetration into host nucleus
cv_term_accession
KW-1163
canonical
uniprot_keyword
KW-1163
canonical
name
Viral penetration into host nucleus
uniprot
synonym
Entry of virus into host nucleus
uniprot
synonym
Virion entry into host nucleus
uniprot
synonym
Virion penetration into host nucleus
uniprot
definition
Viral protein necessary for the penetration of the viral genome into the host cell nucleus either via active nuclear transport through nuclear pore complexes (NPCs) or DNA injection through the nuclear membrane. Nuclear membrane permeabilization might also be possible. Viruses can also enter the nucleus during mitosis when the nuclear membrane temporarily disintegrates (e.g. most retroviruses). All these strategies to cross the nuclear envelope barrier are associated with various levels of capsid disassembly, since virus can pass intact (e.g. papovaviruses) or, in the case of injection, only the viral genome enters the nucleus (e.g. herpesviruses).
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords