Slfn13
entrez
303378
canonical
uniprot
Q5U311
canonical
ensembl
ENSRNOG00000021412
resolver
ensembl
ENSRNOG00055029132
resolver
ensembl
ENSRNOG00060028362
resolver
ensembl
ENSRNOG00065020659
resolver
ensp
ENSRNOP00000052816
resolver
ensp
ENSRNOP00000067903
resolver
ensp
ENSRNOP00055041547
resolver
ensp
ENSRNOP00060041169
resolver
ensp
ENSRNOP00065028133
resolver
enst
ENSRNOT00000076618
resolver
enst
ENSRNOT00055050463
resolver
enst
ENSRNOT00060049331
resolver
enst
ENSRNOT00065035004
resolver
genesymbol
Slfn13
resolver
uniprot
A0A096MJD4
resolver
uniprot
A0A096MKD0
resolver
uniprot_entry
SLN13_RAT
resolver
uniprot_sec
A0A096MJD4
resolver
uniprot_sec
A0A096MKD0
resolver
amino_acid_sequence
MEIHPSLVVEPSYPDLIIHAGEVTLGEKDRNKMDSKKKRLEKARITEAACALLNSGGGVIVMQMSNKSEHPVEMGLDLETSLRELIPSSDLQAFIETKQQGDLFYIFVKSWSCSPKDGSTKPRICSLSSSLYCRSLTSKLPLDSKETFEFLERKKTCVKGSLTDGKGPPAKIPRLMYQNDLESNPAFEIFQSERLEYGQRLPFSESASIEFKQFSTRRAHEYIKSVIPEYISAFANTQGGYLLFGVDDESKRVLGCPKDNVDRDSLKAVVNEAISKLPVFHFCSSKEKVSYKTRVIDVFKEGNLYGYLCVIKVERFCCAVFSEAPISWMADKENGVYSLNTEKWVRMMVDIGPEAASSKQSSLDDLSKDFECQLSLSNSPPHCRPVYSKKGLEHKGDLQKRLFQVSADCFKYTPESLWRELCSQHERLENLISQQMCSFSCGLLILSRSWAVDLNLEGKQGVICDALLIAENSPPTLYTILEEQDELGQDYCTRTAFTLKQKLVNTGGYTGRVCVMTKVLCLSSQNNIETNGNSVSLIDYPRSYNLANIQEMEDLLQALVIVLLNFSSFLSDQLGCEILNLLTVQQYEILSKSLHKTRKLFVHGMPGSGKTIIAMKIMEKIKNTFHCERDSILYICENQLLRDFIRAKNVCRAVTRKTFMTPNFEVEKIQHIIVDEAQNFRTENGDWYMKAKRITQRMKTCPQIFWIFLDYFQTSHQKESGLPDFLHQYPKEELTKVVRNADKIAEFLQKISEKIRSNPPPIIPRESLNMVCEFNWSQGVSGTCKLLTSLGLEQMARYVAERCYFFLKNGYSAQDIAVLFSTEDEKDNNEDMFLREIRNRTSQIDDAYHLYMFDSIRRFSGLERSIVFGIDPRTAEKSIFHNLMLCLASRARKHLYILSKVPNPFNF
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550). Does not act on tRNA(Sec) (PubMed:29563550). {ECO:0000269|PubMed:29563550}.
uniprot
proteins
mass_dalton
103655
uniprot
proteins
mutagenesis
MUTAGEN 34; /note="D->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 38; /note="K->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 39; /note="R->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 42; /note="K->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 47; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 84; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 96; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 146; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 193; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 205; /note="E->A: Abolished endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 210; /note="E->A: Abolished endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 217; /note="R->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 221; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 224; /note="K->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 229; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 249; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 259; /note="D->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 276; /note="K->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 281; /note="H->A: Renders the protein insoluble."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 283; /note="C->A: Renders the protein insoluble."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 318; /note="C->A: Renders the protein insoluble."; /evidence="ECO:0000269|PubMed:29563550"; MUTAGEN 323; /note="E->A: Reduced endoribonuclease activity."; /evidence="ECO:0000269|PubMed:29563550
uniprot
proteins
protein_family
Schlafen family
uniprot
proteins
protein_family
Subgroup III subfamily
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
29563550
uniprot
proteins
sequence_length
907
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q68D06}.
uniprot
proteins