Slc4a5
entrez
297386
canonical
uniprot
Q6RI88
canonical
ensembl
ENSRNOG00000010378
resolver
ensp
ENSRNOP00000014249
resolver
ensp
ENSRNOP00000074224
resolver
ensp
ENSRNOP00000091246
resolver
enst
ENSRNOT00000014249
resolver
genesymbol
Slc4a5
resolver
uniprot
A0A8L2Q6Y5
resolver
uniprot_entry
A0A8L2Q6Y5_RAT
resolver
uniprot_entry
S4A5_RAT
resolver
amino_acid_sequence
MKVEEKAGVKKLEPTSYRRRHPEQDFPSIHIGFPVPGYSQRKSDSKGHLSGLQRVQWSLQPDKSQQDLAGPDGIKASSLGGSVDFTKRIRSPAAEQLQDILGEEDEAPNPTLFTEMDTLQHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEGGLLRPELRERVSYVLLRKHRHQTKKPIHRSLADIGKSVSTTNRSSARSPSAGPTLHHSTEDLRIRQSTSYGHLCHAQSRSMNDISHTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLAQSSMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGVDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGRSGASAGGGGSGGGAGGSGAGGGGSGNEAEMPAMHEIGEELIWTGRFFGGLRLDVKRKLPWFPSDFYDGFHIQSISAVLFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKANGLDYMEFRLWIGLHSAIQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINTDFKPDSITTYKCECVAPDTVNTTTVNDSALLVPNTNMSVYTPLNLTALDWSLLSKKECLSYGGRLLGSSCQFVPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRTLVADFSIVFSILLFCGIDACFGLQTPKLHVPNVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLRKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGVMVFILTGISVFLAPILKYIPMPVLYGVFLYMGVASLNGIQFWDRCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLALLWILKSTMAAIIFPVMILGLIIVRRLLDLIFSQHDLAWIDNILPEKEKKESDRKKRRKEVHENTDKEPQFLPPSVVKIPMEGIPSDPQNGIHCVGRKRSSSWSHSL
uniprot
proteins
function
FUNCTION: Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. {ECO:0000250|UniProtKB:Q9BY07}.
uniprot
proteins
mass_dalton
123944
uniprot
proteins
protein_family
Anion exchanger (TC 2.A.31) family
uniprot
proteins
pubmed
12388414
uniprot
proteins
pubmed
15151908
uniprot
proteins
sequence_length
1112
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000269|PubMed:15151908}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:Q9BY07}; Multi-pass membrane protein {ECO:0000255}. Note=Localized predominantly to the basolateral sinusoidal membrane in hepatocytes. {ECO:0000269|PubMed:15151908}.
uniprot
proteins
transmembrane_region
TRANSMEM 514..536; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 548..579; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 599..620; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 735..753; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 773..792; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 821..839; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 859..875; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 881..900; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 921..940; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 946..966; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 993..1010; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1016..1033; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins