MBNL3
entrez
55796
canonical
uniprot
Q9NUK0
canonical
ensembl
ENSG00000076770
resolver
ensp
ENSP00000359876
resolver
ensp
ENSP00000359881
resolver
ensp
ENSP00000359886
resolver
ensp
ENSP00000359890
resolver
ensp
ENSP00000359894
resolver
ensp
ENSP00000377848
resolver
ensp
ENSP00000402128
resolver
ensp
ENSP00000406014
resolver
ensp
ENSP00000439618
resolver
ensp
ENSP00000513826
resolver
ensp
ENSP00000513866
resolver
ensp
ENSP00000522942
resolver
ensp
ENSP00000522946
resolver
ensp
ENSP00000651300
resolver
ensp
ENSP00000651306
resolver
enst
ENST00000370857
resolver
enst
ENST00000473364
resolver
genesymbol
MBNL3
resolver
genesymbol_syn
CHCR
resolver
genesymbol_syn
MBLX39
resolver
genesymbol_syn
MBXL
resolver
hgnc
HGNC:20564
resolver
uniprot
A0A8V8TNS0
resolver
uniprot
B1AKI6
resolver
uniprot
Q5JXN8
resolver
uniprot
Q5JXN9
resolver
uniprot
Q5JXP4
resolver
uniprot
Q6UDQ1
resolver
uniprot
Q8IUR4
resolver
uniprot
Q8TAD9
resolver
uniprot
Q8TAF4
resolver
uniprot
Q9H0Z7
resolver
uniprot
Q9UF37
resolver
uniprot_entry
A0A8V8TNS0_HUMAN
resolver
uniprot_entry
B1AKI6_HUMAN
resolver
uniprot_entry
MBNL3_HUMAN
resolver
uniprot_sec
Q5JXN8
resolver
uniprot_sec
Q5JXN9
resolver
uniprot_sec
Q5JXP4
resolver
uniprot_sec
Q6UDQ1
resolver
uniprot_sec
Q8IUR4
resolver
uniprot_sec
Q8TAD9
resolver
uniprot_sec
Q8TAF4
resolver
uniprot_sec
Q9H0Z7
resolver
uniprot_sec
Q9UF37
resolver
amino_acid_sequence
MTAVNVALIRDTKWLTLEVCREFQRGTCSRADADCKFAHPPRVCHVENGRVVACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQLMLQNAQMSSLGSFPMTPSIPANPPMAFNPYIPHPGMGLVPAELVPNTPVLIPGNPPLAMPGAVGPKLMRSDKLEVCREFQRGNCTRGENDCRYAHPTDASMIEASDNTVTICMDYIKGRCSREKCKYFHPPAHLQARLKAAHHQMNHSAASAMALQPGTLQLIPKRSALEKPNGATPVFNPTVFHCQQALTNLQLPQPAFIPAGPILCMAPASNIVPMMHGATPTTVSAATTPATSVPFAAPTTGNQLKF
uniprot
proteins
function
FUNCTION: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction. {ECO:0000269|PubMed:12297108, ECO:0000269|PubMed:15257297}.
uniprot
proteins
mass_dalton
38532
uniprot
proteins
protein_family
Muscleblind family
uniprot
proteins
pubmed
11929853
uniprot
proteins
pubmed
12297108
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15257297
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
354
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11929853}. Cytoplasm {ECO:0000269|PubMed:11929853}. Note=Greater concentration in the nucleus. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.
uniprot
proteins