Hcar1
entrez
243270
canonical
uniprot
Q8C131
canonical
ensembl
ENSMUSG00000049241
resolver
ensp
ENSMUSP00000129280
resolver
enst
ENSMUST00000164267
resolver
genesymbol
Hcar1
resolver
genesymbol_syn
Gpr81
resolver
uniprot
B9EJ36
resolver
uniprot
E9PZR8
resolver
uniprot_entry
E9PZR8_MOUSE
resolver
uniprot_entry
HCAR1_MOUSE
resolver
uniprot_sec
B9EJ36
resolver
amino_acid_sequence
MDNGSCCLIEGEPISQVMPPLLILVFVLGALGNGIALCGFCFHMKTWKSSTIYLFNLAVADFLLMICLPLRTDYYLRRRHWIFGDIACRLVLFKLAMNRAGSIVFLTVVAVDRYFKVVHPHHMVNAISNRTAAATACVLWTLVILGTVYLLMESHLCVQGTLSSCESFIMESANGWHDVMFQLEFFLPLTIILFCSVNVVWSLRRRQQLTRQARMRRATRFIMVVASVFITCYLPSVLARLYFLWTVPTSACDPSVHTALHVTLSFTYLNSMLDPLVYYFSSPSLPKFYTKLTICSLKPKRPGRTKTRRSEEMPISNLCSKSSIDGANRSQRPSDGQWDLQVC
uniprot
proteins
function
FUNCTION: Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway. {ECO:0000269|PubMed:18174606, ECO:0000269|PubMed:19047060}.
uniprot
proteins
mass_dalton
38927
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18174606
uniprot
proteins
pubmed
19047060
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
343
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9BXC0}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 50..70; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 91..111; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 132..152; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 183..203; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 221..241; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 260..280; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins