Suclg2
entrez
20917
canonical
uniprot
Q9Z2I8
canonical
ensembl
ENSMUSG00000061838
resolver
ensp
ENSMUSP00000078774
resolver
ensp
ENSMUSP00000144827
resolver
genesymbol
Suclg2
resolver
uniprot
Q3T9B8
resolver
uniprot
Q3TJQ5
resolver
uniprot
Q3TK63
resolver
uniprot
Q66JT3
resolver
uniprot
Q7TMY3
resolver
uniprot
Q80VV1
resolver
uniprot
Q8K2K9
resolver
uniprot_entry
SUCB2_MOUSE
resolver
uniprot_sec
Q3T9B8
resolver
uniprot_sec
Q3TJQ5
resolver
uniprot_sec
Q3TK63
resolver
uniprot_sec
Q66JT3
resolver
uniprot_sec
Q7TMY3
resolver
uniprot_sec
Q80VV1
resolver
uniprot_sec
Q8K2K9
resolver
amino_acid_sequence
MASPVAIAAQAGKLLRERALRPLLAVRSQAGHLTPRRWLNLQEYQSKKLMSEHGVRVQRFFVANTAKEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLKGGVHLTKDPKVVGELAQQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRSHNGPVIVGSPQGGVDIEEVAASSPELIFKEQIDIFEGIKDSQAQRMAENLGFLGSLKNQAADQITKLYHLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSENEPIENEAARYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQVYEAFKLLTSDPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEAQNILKSSGLPITSAVDLEDAAKKAVASVAKK
uniprot
proteins
ec_number
6.2.1.-
uniprot
proteins
ec_number
6.2.1.4
uniprot
proteins
function
FUNCTION: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Also able to act as a GTP-specific itaconyl- and malyl-CoA synthetase. {ECO:0000255|HAMAP-Rule:MF_03221}.
uniprot
proteins
mass_dalton
46840
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_03221}.
uniprot
proteins
protein_family
GTP-specific subunit beta subfamily
uniprot
proteins
protein_family
Succinate/malate CoA ligase beta subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
9765291
uniprot
proteins
sequence_length
433
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03221}.
uniprot
proteins