Fgl1
entrez
246186
canonical
uniprot
Q5M8C6
canonical
ensembl
ENSRNOG00000010714
resolver
ensembl
ENSRNOG00055011433
resolver
ensembl
ENSRNOG00060006874
resolver
ensembl
ENSRNOG00065003002
resolver
ensp
ENSRNOP00000014248
resolver
ensp
ENSRNOP00000073912
resolver
ensp
ENSRNOP00055015636
resolver
ensp
ENSRNOP00060008435
resolver
ensp
ENSRNOP00065002997
resolver
enst
ENSRNOT00000014248
resolver
enst
ENSRNOT00055019403
resolver
enst
ENSRNOT00060011299
resolver
enst
ENSRNOT00065004214
resolver
genesymbol
Fgl1
resolver
uniprot
A0A140TAA6
resolver
uniprot
Q8K583
resolver
uniprot_entry
A0A140TAA6_RAT
resolver
uniprot_entry
FGL1_RAT
resolver
uniprot_entry
Q8K583_RAT
resolver
amino_acid_sequence
MGEIRSFVLITVALILGKESWVLGDENCLQEQVRLRAQVRQLETRVKQQQVVIAQLLHEKEVQFLDRGQEDSFIDLGGKRHYADCSEIYNDGFKHSGFYKIKPLQSLAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWNDYENGFGNFVQSNGEYWLGNKNINLLTMQGDYTLKIDLTDFEKNSRFAQYEKFKVGDEKSFYELNIGEYSGTAGDSLSGTFHPEVQWWASHQTMKFSTRDRDNDNYNGNCAEEEQSGWWFNRCHSANLNGVYYQGPYRAETDNGVVWYTWRGWWYSLKSVVMKIRPSDFIPNIV
uniprot
proteins
function
FUNCTION: Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a ligand of LAG3. LAG3-binding initiates a signaling that inhibits the T-cell receptor (TCR) in the immunological synapse, preventing T-cell activation. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes. {ECO:0000250|UniProtKB:Q08830}.
uniprot
proteins
mass_dalton
36476
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18039467
uniprot
proteins
sequence_length
314
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18039467}. Note=Secreted in the blood plasma. {ECO:0000269|PubMed:18039467}.
uniprot
proteins