Prmt7
entrez
361402
canonical
uniprot
Q5U4E8
canonical
ensembl
ENSRNOG00000000258
resolver
ensembl
ENSRNOG00055018339
resolver
ensembl
ENSRNOG00060012672
resolver
ensembl
ENSRNOG00065012211
resolver
ensp
ENSRNOP00000075738
resolver
ensp
ENSRNOP00055025144
resolver
ensp
ENSRNOP00060017046
resolver
ensp
ENSRNOP00065015232
resolver
enst
ENSRNOT00000081312
resolver
enst
ENSRNOT00055031182
resolver
enst
ENSRNOT00060021575
resolver
enst
ENSRNOT00065019882
resolver
genesymbol
Prmt7
resolver
uniprot_entry
ANM7_RAT
resolver
amino_acid_sequence
MKVFCGRANPTTGSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDKGQKALVLDIGTGTGLLSMMAVTAGADFCYAVEVFKPMAEAAVKIVEKNGFSDKIKVINKHSTEVTVGPDGDLPCRANILVTELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLVESKRMWSWNKLFPVRVQTGLGEQLIIPPSELERCPGAPSVYDIQLNQVSPADFTVLSDVLPMFSVDFSKQVSSSAACHSKQFVPLASGQAQVVLSWWDIEMDPEGKIKCTMAPFWAQTDPQELQWRDHWMQCVYFLPQEEPIMQGSPRCLAAHHDDYCVWYSLQRTSPDENNSAYQVRPVCDCQAHLLWNRPRFGEINDQDRTDHYARALRTMLMPGSICLCVSDGSLLSVLAHHLGAEQVFTVESSVASYRLMKRIFKVNHLEDKITVINKRPELLTSADLEGKKVSLLLGEPFFTTSLLPWHNLYFWYVRTSVDQHLAPGAVVMPQAASLHAVIVEFRDLWRIRSPCGDCEGFDVHIMDDMIKHSLDFRESREAEPQPLWEYPCRSLSEPRQILTFDFQQPIPQQPMQSRGVMELRRPGKSHGAVLWMEYQLTPDSTVSTGLMNPAEDKGDCCWNPHCKQAVYFLSATLDPSAPLDGPQSVSYAVEFHPLTGDITMEFRLADDTLN
uniprot
proteins
ec_number
2.1.1.321
uniprot
proteins
function
FUNCTION: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo. {ECO:0000250|UniProtKB:Q9NVM4}.
uniprot
proteins
mass_dalton
78346
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
PRMT7 subfamily
uniprot
proteins
protein_family
Protein arginine N-methyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
693
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins