Mbip
entrez
217588
canonical
uniprot
Q99LQ1
canonical
ensembl
ENSMUSG00000021028
resolver
ensp
ENSMUSP00000021416
resolver
ensp
ENSMUSP00000206179
resolver
ensp
ENSMUSP00000330811
resolver
enst
ENSMUST00000021416
resolver
genesymbol
Mbip
resolver
uniprot
Q3TBM3
resolver
uniprot_entry
MBIP1_MOUSE
resolver
uniprot_sec
Q3TBM3
resolver
amino_acid_sequence
MAAAAELSSSSGSERSLEQCSSPLLTREVLCEVFRSLHTLTRQLNLRDDVVKITIDWNRLQSLSASQPALLLTALEQHVLYLQPFLAKLQSLMKENSTATEIRQTEAETKSELRAIHPTEDLQDEGKPKDCDVGDVKKTQNLFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVREFCNVIDCNQENSCARTDAVFTPYPGFKSHVKVSRVVNTYGPQTRPEGIAGSGHKPTGMLRDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVNFSGKRRKVQPPQQNYSLAELDEKISALKRALLRKSREADSMAAHLP
uniprot
proteins
function
FUNCTION: Functions as part of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Together with MOCS2B, inhibits the activity of stress kinase EIF2AK2/PKR; this may lead to effects such as suppression of JNK activation and subsequent stress-responsive transcription, or suppression of eIF2a phosphorylation to favor translation. {ECO:0000250|UniProtKB:Q9NS73}.
uniprot
proteins
mass_dalton
38333
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NS73}. Cytoplasm {ECO:0000250|UniProtKB:Q9NS73}. Note=Shows a cytoplasmic localization when coexpressed with MAP3K12. {ECO:0000250|UniProtKB:Q9NS73}.
uniprot
proteins