Ppme1
entrez
72590
canonical
uniprot
Q8BVQ5
canonical
ensembl
ENSMUSG00000030718
resolver
ensp
ENSMUSP00000032963
resolver
enst
ENSMUST00000032963
resolver
genesymbol
Ppme1
resolver
genesymbol_syn
Pme1
resolver
uniprot
Q3U392
resolver
uniprot
Q3UJX8
resolver
uniprot
Q3UKE0
resolver
uniprot
Q8K311
resolver
uniprot
Q91YR8
resolver
uniprot
Q9CSP7
resolver
uniprot_entry
PPME1_MOUSE
resolver
uniprot_sec
Q3U392
resolver
uniprot_sec
Q3UJX8
resolver
uniprot_sec
Q3UKE0
resolver
uniprot_sec
Q8K311
resolver
uniprot_sec
Q91YR8
resolver
uniprot_sec
Q9CSP7
resolver
amino_acid_sequence
MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFTPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRGHGETKVKNSEDLSAETMAKDVGNVVEAMYGDLPPPVMLIGHSMGGAIAVHTAAANLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC
uniprot
proteins
ec_number
3.1.1.89
uniprot
proteins
function
FUNCTION: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
42256
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SIK1 following increases in intracellular sodium, leading to dissociation from the protein phosphatase 2A (PP2A) complex and subsequent dephosphorylation of sodium/potassium-transporting ATPase ATP1A1. {ECO:0000250}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
pubmed
10318862
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
386
uniprot
proteins