Aen
entrez
361594
canonical
uniprot
B2GUW6
canonical
ensembl
ENSRNOG00000018421
resolver
ensembl
ENSRNOG00055007854
resolver
ensembl
ENSRNOG00060003740
resolver
ensembl
ENSRNOG00065029745
resolver
ensp
ENSRNOP00000062841
resolver
ensp
ENSRNOP00055010564
resolver
ensp
ENSRNOP00060004604
resolver
ensp
ENSRNOP00065042326
resolver
enst
ENSRNOT00000064438
resolver
enst
ENSRNOT00055013188
resolver
enst
ENSRNOT00060006197
resolver
enst
ENSRNOT00065051392
resolver
genesymbol
Aen
resolver
genesymbol_syn
Isg20l1
resolver
uniprot_entry
AEN_RAT
resolver
amino_acid_sequence
MVPREVPESSLTSLKTKDVARRRHKRRSRQHQRFMARKALLQEQESLSMVPGPGLCPLPSPTQTPAGTEASGNRKQRTKARSGSKGLCSKRPVPREAPSSGPSKYVAIDCEMVGTGPQGRVSELARCSVVSYSGDVLYDKYIRPEMPIVDYRTRWSGITRQHMHKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPGSQIRDTTYVPNLLSQPSSLTRARVSLKDLALNLLHKKIQVGHHGHSSVEDAMTAMELYQLVEVQWEQQVASTAKAHPEDRGPDSSTDVEQYMDDQYWPEDLAQSTRGDTREAQDRQEGEEGQGARSAPP
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37061
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8WTP8}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q8WTP8}. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction (By similarity). {ECO:0000250|UniProtKB:Q8WTP8}.
uniprot
proteins