Npffr2
entrez
104443
canonical
uniprot
Q924H0
canonical
ensembl
ENSMUSG00000035528
resolver
ensp
ENSMUSP00000040033
resolver
enst
ENSMUST00000048557
resolver
genesymbol
Npffr2
resolver
genesymbol_syn
Gpr74
resolver
genesymbol_syn
Npff2
resolver
uniprot
Q8BKR6
resolver
uniprot_entry
NPFF2_MOUSE
resolver
uniprot_sec
Q8BKR6
resolver
amino_acid_sequence
MSEKWDSNSSESWNHIWSGNDTQHHWYSDINITYVNYYLHQPQVAAVFISSYLLIFVLCMVGNTVVCFIVIRNRHMHTVTNFFILNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVTIVIIWGLAIAIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPRHEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTAAHCTGKQRPVQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYTDLSPNKLRIINIYIYPFAHWLAFCNSSVNPIIYGFFNENFRNGFQDAFQICQKKAKPQEAYSLRAKRNIVINTSGLLVQEPVSQNPGGENLGCGKSADNPTQESLIEEMGEATNSTVA
uniprot
proteins
function
FUNCTION: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. {ECO:0000250|UniProtKB:Q9Y5X5}.
uniprot
proteins
mass_dalton
47449
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
417
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9Y5X5}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 46..66; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 83..103; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 120..140; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 161..181; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 218..238; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 275..295; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 311..331; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins