Slc44a2
entrez
68682
canonical
uniprot
Q8BY89
canonical
ensembl
ENSMUSG00000057193
resolver
ensp
ENSMUSP00000034697
resolver
ensp
ENSMUSP00000150147
resolver
ensp
ENSMUSP00000273821
resolver
genesymbol
Slc44a2
resolver
genesymbol_syn
Ctl2
resolver
uniprot
Q8K2F1
resolver
uniprot_entry
CTL2_MOUSE
resolver
uniprot_sec
Q8K2F1
resolver
amino_acid_sequence
MGKDSQNYYGKHGTPQKYDPTFKGPIYNRGCTDVICCVLLFLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNADKPFLFYFNIVKCANPLVLLEFHCPTPQICVKQCPDRYLTLLSARNTRDFDYYKQFCVPGFQNNKGVTEILRDGECPAVITPSKPLAQRCFPAIHASKGVLMVGNETTYEDGHGARKNITDLVEGAKKANKILEARQLAMQIFEDYTVSWYWIIIGLVIAMVLSLLFIVLLRFLAGIMVWVMIVMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDLRVYLHLRQTWMAFMIILSILEVVIILLLIFLRKRILIAIALIKEASRAVGHVMCSLLYPLVTFFLLCLCIAYWASTSVFLSTSNTAVYKVVDDTACPLLRKTCNPETFPLRNESLQCPTARCQFAFYGGESTYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWAMRKPDDMPAFPLFSAFGRALRYHTGSLAFGSLILAIVQIIRVMLEYLDQRLKAAQNKFAKFLMVCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIIGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTNKKVAES
uniprot
proteins
function
FUNCTION: Choline/H+ antiporter, mainly in mitochondria. Also acts as a low-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway. {ECO:0000250|UniProtKB:Q8IWA5}.
uniprot
proteins
mass_dalton
80110
uniprot
proteins
post_translational_modification
PTM: Glycosylated, glycosylation differs from tissue to tissue. The molecular mass of the mature glycosylated protein is highest in kidney, followed by lung, colon and spleen, then brain and tongue. {ECO:0000269|PubMed:20665236}.
uniprot
proteins
protein_family
CTL (choline transporter-like) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
19656770
uniprot
proteins
pubmed
20665236
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
706
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8IWA5}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8IWA5}; Multi-pass membrane protein {ECO:0000255}. Note=Mainly expressed in mitochondria. {ECO:0000250|UniProtKB:B4F795}.
uniprot
proteins
transmembrane_region
TRANSMEM 34..54; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 233..253; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 257..277; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 316..336; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 365..385; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 455..477; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 505..525; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 564..584; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 600..620; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 639..659; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins