Tspo
entrez
24230
canonical
uniprot
P16257
canonical
ensembl
ENSRNOG00000010549
resolver
ensembl
ENSRNOG00055029344
resolver
ensembl
ENSRNOG00060025807
resolver
ensembl
ENSRNOG00065029087
resolver
ensp
ENSRNOP00000014089
resolver
ensp
ENSRNOP00055041899
resolver
ensp
ENSRNOP00060036993
resolver
ensp
ENSRNOP00065041276
resolver
enst
ENSRNOT00000014089
resolver
enst
ENSRNOT00055050855
resolver
enst
ENSRNOT00060044640
resolver
enst
ENSRNOT00065050252
resolver
genesymbol
Tspo
resolver
genesymbol_syn
Bzrp
resolver
genesymbol_syn
Mbr
resolver
uniprot_entry
TSPO_RAT
resolver
amino_acid_sequence
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
uniprot
proteins
function
FUNCTION: Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis (By similarity). Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:2555358). {ECO:0000250, ECO:0000269|PubMed:20336621, ECO:0000269|PubMed:2555358}.
uniprot
proteins
mass_dalton
18940
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
TspO/BZRP family
uniprot
proteins
pubmed
1332914
uniprot
proteins
pubmed
20336621
uniprot
proteins
pubmed
2555358
uniprot
proteins
sequence_length
169
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane {ECO:0000269|PubMed:2555358}; Multi-pass membrane protein {ECO:0000269|PubMed:2555358}.
uniprot
proteins
transmembrane_region
TRANSMEM 6..26; /note="Helical; Name=1"; /evidence="ECO:0000250"; TRANSMEM 47..67; /note="Helical; Name=2"; /evidence="ECO:0000250"; TRANSMEM 80..100; /note="Helical; Name=3"; /evidence="ECO:0000250"; TRANSMEM 106..126; /note="Helical; Name=4"; /evidence="ECO:0000250"; TRANSMEM 135..155; /note="Helical; Name=5"; /evidence="ECO:0000250
uniprot
proteins