ECHDC1
entrez
55862
canonical
uniprot
Q9NTX5
canonical
ensembl
ENSG00000093144
resolver
ensp
ENSP00000357274
resolver
ensp
ENSP00000401751
resolver
ensp
ENSP00000402492
resolver
ensp
ENSP00000404866
resolver
ensp
ENSP00000436109
resolver
ensp
ENSP00000436585
resolver
ensp
ENSP00000436703
resolver
ensp
ENSP00000564328
resolver
ensp
ENSP00000776243
resolver
genesymbol
ECHDC1
resolver
hgnc
HGNC:21489
resolver
uniprot
A6NFJ5
resolver
uniprot
B7Z8S0
resolver
uniprot
E9PEN7
resolver
uniprot
E9PR31
resolver
uniprot
F8W851
resolver
uniprot
Q5TEF6
resolver
uniprot
Q5TEF7
resolver
uniprot
Q5TEG0
resolver
uniprot
Q5TEG4
resolver
uniprot
Q9NZ30
resolver
uniprot
V9HW18
resolver
uniprot_entry
ECHD1_HUMAN
resolver
uniprot_sec
A6NFJ5
resolver
uniprot_sec
B7Z8S0
resolver
uniprot_sec
E9PEN7
resolver
uniprot_sec
E9PR31
resolver
uniprot_sec
F8W851
resolver
uniprot_sec
Q5TEF6
resolver
uniprot_sec
Q5TEF7
resolver
uniprot_sec
Q5TEG0
resolver
uniprot_sec
Q5TEG4
resolver
uniprot_sec
Q9NZ30
resolver
uniprot_sec
V9HW18
resolver
amino_acid_sequence
MALKQEMAKSLLKTASLSGRTKLLHQTGLSLYSTSHGFYEEEVKKTLQQFPGGSIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIAKKGKFNK
uniprot
proteins
ec_number
4.1.1.94
uniprot
proteins
function
FUNCTION: Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading (PubMed:22016388). Acts preferentially on (S)-ethylmalonyl-CoA but also has some activity on the (R)-isomer (By similarity). Also has methylmalonyl-CoA decarboxylase activity at lower level (By similarity). {ECO:0000250|UniProtKB:Q9D9V3, ECO:0000269|PubMed:22016388}.
uniprot
proteins
mass_dalton
33698
uniprot
proteins
protein_family
Enoyl-CoA hydratase/isomerase family
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22016388
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
307
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000305|PubMed:22016388}.
uniprot
proteins