LMAN2
entrez
10960
canonical
uniprot
Q12907
canonical
ensembl
ENSG00000169223
resolver
ensp
ENSP00000303366
resolver
enst
ENST00000303127
resolver
genesymbol
LMAN2
resolver
genesymbol_syn
C5orf8
resolver
hgnc
HGNC:16986
resolver
uniprot
A0A384NPY7
resolver
uniprot
Q53HH1
resolver
uniprot_entry
A0A384NPY7_HUMAN
resolver
uniprot_entry
LMAN2_HUMAN
resolver
uniprot_sec
Q53HH1
resolver
amino_acid_sequence
MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY
uniprot
proteins
function
FUNCTION: Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
40229
uniprot
proteins
pubmed
10444376
uniprot
proteins
pubmed
12754519
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:10444376}; Single-pass type I membrane protein {ECO:0000269|PubMed:10444376}. Golgi apparatus membrane {ECO:0000269|PubMed:10444376}; Single-pass membrane protein {ECO:0000269|PubMed:10444376}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:10444376}; Single-pass type I membrane protein {ECO:0000269|PubMed:10444376}.
uniprot
proteins
transmembrane_region
TRANSMEM 323..345; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins