Ddx10
entrez
77591
canonical
uniprot
Q80Y44
canonical
ensembl
ENSMUSG00000053289
resolver
ensp
ENSMUSP00000065198
resolver
ensp
ENSMUSP00000322664
resolver
enst
ENSMUST00000065630
resolver
genesymbol
Ddx10
resolver
uniprot_entry
DDX10_MOUSE
resolver
amino_acid_sequence
MGKTVASLGQGTRPDPVRSFNRWKKKHSHRQHQKKERRKQLKKPEWQVEREGISRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETICFHATNLQMLVLDEADRILDMGFADTMNAIIENLPKKRQTLLFSATQTKSVKDLARLSLKDPEYVWVHEKAKYSTPATLEQNYIICELHQKISVLFSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGISILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEEQGMVQQLLQKKVPVKEIKINPEKLIDVQKKLESFLAQDQDLKERAQRCFVSYIRSVYLMKDKEVFNVSKLPITEYALSLGLAVAPRIRFLQKLEKQPSTELVKNPVTEAVPPRAPSLPNDEADESPAYVSEKMSVLHKSGERLEETEHRLASGDGDEEQDEETEDEETEDHLGKAREPHTESVVSIEEAQKVKEVSVQFLNRDDDDEDGPDADFLTVKRRDVFGLDLKENEALSKKEPSKSSVKKKLTKVAEAKKVMKRSFKVNKKITFTDEGELVQQWPQIQKCAIKDVEEEDDTGGINLDKAKERLQEEDKFDKEEYRKKIKAKHRERRLKEREARREANKRQAKARDEEEAFLDWSDEDDGGFDPSTLPDPDKHRSSEESESEDTNHKMSDTKKKQETRKRNNTEDDDVRPRSRHGKKAKWETVEPLDTGLSLAEDEELVLHLLKSQN
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: Putative ATP-dependent RNA helicase that plays various role in innate immunity or inflammation. Plays a role in the enhancement of AIM2-induced inflammasome activation by interacting with AIM2 and stabilizing its protein level. Negatively regulates viral infection by promoting interferon beta production and interferon stimulated genes/ISGs expression. {ECO:0000250|UniProtKB:Q13206}.
uniprot
proteins
mass_dalton
100739
uniprot
proteins
protein_family
DDX10/DBP4 subfamily
uniprot
proteins
protein_family
DEAD box helicase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
875
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q13206}. Nucleus {ECO:0000250|UniProtKB:Q13206}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q13206}.
uniprot
proteins