Clasp1
entrez
76707
canonical
uniprot
Q80TV8
canonical
ensembl
ENSMUSG00000064302
resolver
ensp
ENSMUSP00000042266
resolver
ensp
ENSMUSP00000128089
resolver
ensp
ENSMUSP00000137137
resolver
ensp
ENSMUSP00000140019
resolver
ensp
ENSMUSP00000140095
resolver
ensp
ENSMUSP00000140167
resolver
ensp
ENSMUSP00000140593
resolver
ensp
ENSMUSP00000140665
resolver
ensp
ENSMUSP00000140860
resolver
ensp
ENSMUSP00000141105
resolver
ensp
ENSMUSP00000222626
resolver
ensp
ENSMUSP00000222627
resolver
ensp
ENSMUSP00000222628
resolver
ensp
ENSMUSP00000222629
resolver
ensp
ENSMUSP00000222630
resolver
ensp
ENSMUSP00000222632
resolver
enst
ENSMUST00000049404
resolver
enst
ENSMUST00000165223
resolver
enst
ENSMUST00000178710
resolver
enst
ENSMUST00000186349
resolver
enst
ENSMUST00000188710
resolver
enst
ENSMUST00000189262
resolver
enst
ENSMUST00000189570
resolver
enst
ENSMUST00000189738
resolver
enst
ENSMUST00000190571
resolver
enst
ENSMUST00000191445
resolver
genesymbol
Clasp1
resolver
genesymbol_syn
Kiaa0622
resolver
uniprot
A0A087WQ31
resolver
uniprot
A0A087WQ95
resolver
uniprot
A0A087WQF1
resolver
uniprot
A0A087WRE8
resolver
uniprot
A0A087WRK0
resolver
uniprot
A0A087WS18
resolver
uniprot
A5D6Q8
resolver
uniprot
E9Q6L0
resolver
uniprot
E9QKH0
resolver
uniprot
J3QP81
resolver
uniprot
Q505G6
resolver
uniprot
Q6DI75
resolver
uniprot
Q6PG14
resolver
uniprot
Q8BNS4
resolver
uniprot
Q99JH5
resolver
uniprot
Q99JI2
resolver
uniprot
Q9CVU1
resolver
uniprot_entry
A0A087WQ31_MOUSE
resolver
uniprot_entry
A0A087WQ95_MOUSE
resolver
uniprot_entry
A0A087WQF1_MOUSE
resolver
uniprot_entry
A0A087WRE8_MOUSE
resolver
uniprot_entry
A0A087WRK0_MOUSE
resolver
uniprot_entry
A0A087WS18_MOUSE
resolver
uniprot_entry
A5D6Q8_MOUSE
resolver
uniprot_entry
CLAP1_MOUSE
resolver
uniprot_entry
E9Q6L0_MOUSE
resolver
uniprot_entry
E9QKH0_MOUSE
resolver
uniprot_entry
J3QP81_MOUSE
resolver
uniprot_sec
Q505G6
resolver
uniprot_sec
Q6DI75
resolver
uniprot_sec
Q6PG14
resolver
uniprot_sec
Q8BNS4
resolver
uniprot_sec
Q99JH5
resolver
uniprot_sec
Q99JI2
resolver
uniprot_sec
Q9CVU1
resolver
amino_acid_sequence
MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDRQKSADLEHDQTLLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANEKNFDDEDSVDGNRPSSASSSSSKAPSSSRRNVNLGTTRRLMSSSLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTASRGSTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGSPAFSSAAALPPGSYASLGRIRTRRQSSGSTTNVASTPDSRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGLAGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFTPLDRFGLGQSGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTGVGSPSNTIGRTPSRHPSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLSKPPPPFSQPNSIPTAPSHKTLRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKDCDIVSRDGGAASPATEGRGGSEIEGGRMALDNKTSLLNTQPPRAFPGPRAREYNPYPYSDTINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERITKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
uniprot
proteins
function
FUNCTION: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
169227
uniprot
proteins
protein_family
CLASP family
uniprot
proteins
pubmed
11290329
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
18854161
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Golgi apparatus, trans-Golgi network {ECO:0000250}. Note=Localizes to microtubule plus ends. Localizes to centrosomes, kinetochores and the mitotic spindle from prometaphase. Subsequently localizes to the spindle midzone from anaphase and to the midbody from telophase. In migrating cells localizes to the plus ends of microtubules within the cell body and to the entire microtubule lattice within the lamella. Localizes to the cell cortex and this requires ERC1 and PHLDB2. {ECO:0000250}.
uniprot
proteins