Anln
entrez
68743
canonical
uniprot
Q8K298
canonical
ensembl
ENSMUSG00000036777
resolver
ensp
ENSMUSP00000045873
resolver
ensp
ENSMUSP00000344583
resolver
enst
ENSMUST00000040912
resolver
genesymbol
Anln
resolver
uniprot
Q8BL79
resolver
uniprot
Q8BLB3
resolver
uniprot
Q8K2N0
resolver
uniprot
Q9CUY0
resolver
uniprot_entry
ANLN_MOUSE
resolver
uniprot_sec
Q8BL79
resolver
uniprot_sec
Q8BLB3
resolver
uniprot_sec
Q8K2N0
resolver
uniprot_sec
Q9CUY0
resolver
amino_acid_sequence
MDPFTEKLLERTRARRENLQRKMAERPTAVARSAPHAKRGREPLSEASNQQQPLPGGEEKSCTKPSPSKKRCSDKIEVGAPDLENTEPIDVAKPCSPMPAPRQAKPPAPAAISESVAAPAALLSADRGLNSGSEASATSSVKTRMQRLAEQRRHWDSDLTDDVSESSYFAPVPTEDKAASPSKPPISNASATPVGRRGRLANLAATICSWEDDVSHSSAKQNSVQEQPGTACLSKSSSASGASASINSSSVQQEATCCSPRDGNASVRKDPSSNAAHGPLLSASVSSSVKASSPVTAATFITENREAQNPELLHKTASPLKTEARKPCEKPTLSQGAQPKEEANREVCLQSQSKDKLATPGGRGIKPFLERFGERCQEHSKESPSYRASHKTPNITPNTKAIQERLFKQNTCSSTTHLAQQLKQEREKELACLRGRLDKGNLWSAEKNEKSRSKHLETKQEVHCQNTPLKKHQTVASTPLTSVTDKVAENEPAVKLSSTEPAGSTESEMTKSSPLKITLFLEEEKSLKVASDLEVEQNTEAVREVEMSVDDEDINSSRVINDIFSDVLEEGELDVEKSQEEMDQVGAENSEEQEDALNISSMSLLAPLAQTVGVVSLENVISSPPSELRDSNLSAASPKPGKFQRTRVPRAESADSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLGEKKNVFSGQVNIKQKMQELNNDINLQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATEKRALLIDELNKLKSEGPQRRNKTSVISQSEFAPSKGSVTLSEICLPLKADFVCSTAQKTDASNYYYLIMLKAGAEQMVATPLASTANSLSGDALTFPTTFTLHDVSNDFEINIEVYSLVQKKDSLGPDKKKKASKSKAITPKRLLTSITSKSSLHSSVMASPGGLGAVRTSNFTLVGSHTLSLSSVGDTKFALDKVPFLSPLEGHICLKISCQVNSAVEEKGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDERRKNPIGRINLANCISHQIEPANREFCARRNTLELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVIVDIRLWQPDACYKPVGKP
uniprot
proteins
function
FUNCTION: Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis. May play a significant role in podocyte cell migration. {ECO:0000250|UniProtKB:Q9NQW6}.
uniprot
proteins
mass_dalton
122794
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis. {ECO:0000250}.; PTM: Ubiquitinated, and this requires FZR1/CDH1. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1121
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9NQW6}. Cell projection, bleb {ECO:0000250|UniProtKB:Q9NQW6}. Note=Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase. This pattern persists until telophase, when the protein becomes concentrated in the midbody. {ECO:0000250|UniProtKB:Q9NQW6}.
uniprot
proteins