Esrp1
entrez
500409
canonical
uniprot
B2RYD2
canonical
ensembl
ENSRNOG00000008184
resolver
ensp
ENSRNOP00000010846
resolver
ensp
ENSRNOP00000063046
resolver
ensp
ENSRNOP00000092072
resolver
ensp
ENSRNOP00000095508
resolver
enst
ENSRNOT00000010846
resolver
enst
ENSRNOT00000067129
resolver
enst
ENSRNOT00000110297
resolver
enst
ENSRNOT00000110555
resolver
genesymbol
Esrp1
resolver
genesymbol_syn
Rbm35a
resolver
uniprot
A0A8I6AFU1
resolver
uniprot
A0A8I6APB2
resolver
uniprot
A0A8L2QVS8
resolver
uniprot
F1LP81
resolver
uniprot_entry
A0A8I6AFU1_RAT
resolver
uniprot_entry
A0A8I6APB2_RAT
resolver
uniprot_entry
A0A8L2QVS8_RAT
resolver
uniprot_entry
ESRP1_RAT
resolver
uniprot_entry
F1LP81_RAT
resolver
amino_acid_sequence
MTASPDYLVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQLHEVLVRPDQLELTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDLDKLDVAAMAESLNFEKNDSMSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKTELIDGNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTAPIIPVLPQQFVPPTNVRDCVRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCLSPPSYTFPAPAAVIPTEAAIYQPSLLLNPRALQPSTAYYPAGTQLFMNYTAYYPSPPGSPNSLGYFPTAANLSSVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYATEDGLVHANDQARTVPKEWVCI
uniprot
proteins
function
FUNCTION: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity). Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium (By similarity). {ECO:0000250|UniProtKB:Q3US41, ECO:0000250|UniProtKB:Q6NXG1}.
uniprot
proteins
mass_dalton
75021
uniprot
proteins
protein_family
ESRP family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
677
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins