Tmt1b
entrez
366792
canonical
uniprot
Q562C4
canonical
ensembl
ENSRNOG00000007927
resolver
ensembl
ENSRNOG00055014028
resolver
ensembl
ENSRNOG00060027792
resolver
ensembl
ENSRNOG00065013051
resolver
ensp
ENSRNOP00000010760
resolver
ensp
ENSRNOP00055019666
resolver
ensp
ENSRNOP00060040123
resolver
ensp
ENSRNOP00065016557
resolver
enst
ENSRNOT00000010760
resolver
enst
ENSRNOT00055024104
resolver
enst
ENSRNOT00060048207
resolver
enst
ENSRNOT00065021399
resolver
genesymbol
Tmt1b
resolver
genesymbol_syn
Mettl7b
resolver
uniprot_entry
TMT1B_RAT
resolver
amino_acid_sequence
MDVLVPLLQLLVLLLTLPLHLLALLGCWQPICKTYFPYLMATLTARSYKKMESKKRELFSQIKDLKGTSNEVTLLELGCGTGANFQFYPPGCKVTCVDPNPNFEKFLTKSMAENRHLQYERFIVAYGENMKQLADSSMDVVVCTLVLCSVQSPRKVLQEVQRVLKPGGLLFFWEHVSEPQGSQALLWQRVLEPTWKHIGDGCHLTRETWKDIEKAQFSEVQLEWQPPPFKWLPVGPHIMGKAVK
uniprot
proteins
ec_number
2.1.1.9
uniprot
proteins
function
FUNCTION: Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol-containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endoplasmic reticulum of hepatocytes. Selectively methylates S-centered nucleophiles from metabolites such as hydrogen sulfide and dithiothreitol. {ECO:0000250|UniProtKB:Q6UX53}.
uniprot
proteins
mass_dalton
27904
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17004324
uniprot
proteins
pubmed
33649426
uniprot
proteins
sequence_length
244
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:17004324}; Peripheral membrane protein {ECO:0000269|PubMed:17004324}. Lipid droplet {ECO:0000269|PubMed:17004324}. Microsome {ECO:0000250|UniProtKB:Q6UX53}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q6UX53}. Note=Highly concentrated in the perinuclear area of the endoplasmic reticulum (ER) and surrounding lipid droplets. May be associated with the specific regions of the LR that form lipid droplets and targeted to the initial deposits of lipids where the lipid droplets form.
uniprot
proteins