Dbn1
entrez
81653
canonical
uniprot
Q07266
canonical
ensembl
ENSRNOG00000014170
resolver
ensp
ENSRNOP00000019393
resolver
ensp
ENSRNOP00000019569
resolver
enst
ENSRNOT00000019569
resolver
genesymbol
Dbn1
resolver
uniprot
A0A0H2UHL9
resolver
uniprot
A5D6R1
resolver
uniprot
C6L8E0
resolver
uniprot
O70205
resolver
uniprot_entry
A0A0H2UHL9_RAT
resolver
uniprot_entry
C6L8E0_RAT
resolver
uniprot_entry
DREB_RAT
resolver
uniprot_sec
A5D6R1
resolver
uniprot_sec
O70205
resolver
amino_acid_sequence
MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDARLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQSLEAEEAKRRLKDQSIFGDQRDEEEESQMKKSESEVEEAAAIIAQRPDNPREFFRQQERVASASGGSCDAPSPFNHRPGRPYCPFIKASDSGPSSSSSSSSSPPRTPFPYITCHRTPNLSSSLPCSHLDSHRRMAPTPIPTRSPSDSSTASTPITEQIERALDEVTSSQPPPPPPPPPPAQEAQESAPRLDGEEVCKEAKVAAAPQVWAGCAEEPPRAQEPPLLQSSPTEDLMCTESPEQAVLAASPEPDASVTSVADAHAADTIETTTATTATTIADNVTPAAASLIDLWPGNGEEASTPQAEPRVPTPPSGAEASLAEVPLLNEAAQEPLPPVGEGCANLLNFDELPEPPATFCDPEEEAEGEPLAASQVLTMPSALEEVDQVLEQELEPEPHLLTNGETTQKEGTQQASEGYFSQSQEEEFAQSEEPCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD
uniprot
proteins
function
FUNCTION: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (By similarity). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (By similarity). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity). {ECO:0000250|UniProtKB:Q16643, ECO:0000250|UniProtKB:Q9QXS6}.
uniprot
proteins
mass_dalton
77472
uniprot
proteins
post_translational_modification
PTM: ISGylated. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1611026
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
707
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q16643}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q16643}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q16643}. Cell junction {ECO:0000250|UniProtKB:Q16643}. Cell projection {ECO:0000250|UniProtKB:Q9QXS6}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q9QXS6}. Note=In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC). Colocalized with RUFY3 and F-actin at the transitional domain of the axonal growth cone. {ECO:0000250|UniProtKB:Q16643, ECO:0000250|UniProtKB:Q9QXS6}.
uniprot
proteins