Heph
entrez
117240
canonical
uniprot
Q920H8
canonical
ensembl
ENSRNOG00000012294
resolver
ensembl
ENSRNOG00055030920
resolver
ensembl
ENSRNOG00060024560
resolver
ensembl
ENSRNOG00065017695
resolver
ensp
ENSRNOP00000017312
resolver
ensp
ENSRNOP00055044372
resolver
ensp
ENSRNOP00060035253
resolver
ensp
ENSRNOP00065023528
resolver
enst
ENSRNOT00000017312
resolver
enst
ENSRNOT00055053648
resolver
enst
ENSRNOT00060042560
resolver
enst
ENSRNOT00065029613
resolver
genesymbol
Heph
resolver
uniprot_entry
HEPH_RAT
resolver
amino_acid_sequence
MKAGHLLWALLLMHSLCSLPTDGAIRNYYLGIQDIQWNYAPKGRNVITNQTLNNDTVASSFLKSGKNRIGGTYKKTVYKEYSDGTYTNEIAKPAWLGFLGPLLKAEMGDVILIHLKNFASRPYTIHPHGVFYEKDSEGSLYPDGSSGYLKADDSVPPGGSHVYNWSIPEGHAPTEADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGTLDGNSPPQRKDVDHNFFLLFSVIDENLSWHLDDNIATYCSDPASVDKEDGPFQDSNRMHAINGFVFGNLPELSMCAQKHVAWHLFGMGNEIDVHTAFFHGQTLSIRGHRTDVAHIFPATFVTAEMVPQKSGTWLISCVVNSHLKSGMQAFYKVDSCSMDPPVEQLTGKVRQYFIQAHEIQWDYGPIGHDGRTGKSLREPGSGPDKYFQKSSSRIGGTYWKVRYEAFQDETFQERLHQEEETHLGILGPVIRAEVGDTIQVVFYNRASQPFSIQPHGVFYEKSSEGTVYNDGTSYPKVAKSFEKVTYYWTVPPHAGPTAEDPACLTWMYFSAADPTRDTNSGLVGPLLVCKAGALGEDGKQKGVDKEFFLLFTIFDENESWYNNANQAAGMLDSRLLSEDVEGFEDSNRMHAINGFLFSNLPRLDICKGDTVAWHLLGLGTENDVHGVMFEGNTLQLQGMRKSAAMLFPHTFVTAIMQPDNPGIFEIYCQAGSHREAGMQAIYNVSQCSSHQDSPRQHYQASRVYYIMAEEIEWDYCPDRSWELEWYNTSEKDSYGHVFLSNKDGLLGSKYKKAVFREYTDGTFRIPQPRSGPEEHLGILGPLIRGEVGDILTVVFKNKASRPYSIHAHGVLESSTGWPQAAEPGEVLTYQWNIPERSGPGPSDSACVSWIYYSAVDPIKDMYSGLVGPLVICRNGILEPNGGRNDMDREFALLFLIFDENQSWYLKENIATYGPQETSHVNLQDATFLESNKMHAINGKLYANLRGLTVYQGERVAWYMLAMGQDTDIHTVHFHAESFLYQNGHSYRADVVDLFPGTFEVVEMVASNPGAWLMHCHVTDHVHAGMETIFTVLSHEEHFSTMTTITKEIGKAVILQNIGEGNVKMLGMNIPVKNVEILSSALIAICVVLLLIALALGGVVWYQHRQRKLRRNRRSILDDSFKLLSLKQ
uniprot
proteins
ec_number
1.16.3.1
uniprot
proteins
function
FUNCTION: Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body. {ECO:0000250|UniProtKB:Q9Z0Z4}.
uniprot
proteins
mass_dalton
129593
uniprot
proteins
protein_family
Multicopper oxidase family
uniprot
proteins
pubmed
11557513
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1157
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000250|UniProtKB:Q9BQS7}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 1110..1130; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins