Eif2d
entrez
498225
canonical
uniprot
Q5PPG7
canonical
ensembl
ENSRNOG00000004910
resolver
ensembl
ENSRNOG00055020339
resolver
ensembl
ENSRNOG00060014908
resolver
ensembl
ENSRNOG00065021098
resolver
ensp
ENSRNOP00000006768
resolver
ensp
ENSRNOP00000079849
resolver
ensp
ENSRNOP00000104595
resolver
ensp
ENSRNOP00055028210
resolver
ensp
ENSRNOP00060020358
resolver
ensp
ENSRNOP00065028980
resolver
enst
ENSRNOT00000006768
resolver
enst
ENSRNOT00000111867
resolver
enst
ENSRNOT00055034792
resolver
enst
ENSRNOT00060025526
resolver
enst
ENSRNOT00065035943
resolver
genesymbol
Eif2d
resolver
genesymbol_syn
Lgtn
resolver
uniprot
A0A8I5ZPF1
resolver
uniprot_entry
A0A8I5ZPF1_RAT
resolver
uniprot_entry
EIF2D_RAT
resolver
amino_acid_sequence
MFAKAFRVKSNTAIKGSDRRKLRADVTVAFPTLGTDQVSELIPGKEELNVVKLYAHKGDAVTVYTSGGNPILFELEKNLYPTVYTLWSHPDLLPAFITWPLVLEKLVGGADLMLPGVVVPPTGLPQVQQGDLCAIALVGNRAPVAVGVAAMSTAQMLASGLKGKGISVLHTYQDHLWRSGDKSSPPAIAPLDPTDSCEEKADLGLHGNLRSLSLEGEEENGQVPNPEASDDPNSRALSQDSVDGKPLQEQMDELLEQCFLHALKSRVKKADLPLLTSTLLGSHMFSCCPEGQQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSKGVESIVAVDWRHPRITSFIVPEPSLASQTVQEGSREKPYLPPDIKSLYCVPANMTQLFLESGHKKGSTLEGSEVRRIITDYAKRNNLVDADNRNLVKLDPILCDCILEKNEQHLVMKLPWDSLLTRCLKNLQPAYQVTFPGQEPIIKKGKLCPIDITLVLKTYNKKVTVVRNLETYGLDPCSVAAILQQRCQASTIVSPAPGAKDSLQVQVQGNQIHHLGQLLLEEYRLPGKYIQGLEKAPKPGKK
uniprot
proteins
function
FUNCTION: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
62669
uniprot
proteins
protein_family
EIF2D family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
570
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins