DYNLT3
entrez
6990
canonical
uniprot
P51808
canonical
ensembl
ENSG00000165169
resolver
ensp
ENSP00000367841
resolver
enst
ENST00000378578
resolver
genesymbol
DYNLT3
resolver
genesymbol_syn
TCTE1L
resolver
genesymbol_syn
TCTE1XL
resolver
hgnc
HGNC:11694
resolver
uniprot
Q6ICS3
resolver
uniprot_entry
DYLT3_HUMAN
resolver
uniprot_sec
Q6ICS3
resolver
amino_acid_sequence
MEEYHRHCDEVGFNAEEAHNIVKECVDGVLGGEDYNHNNINQWTASIVEQSLTHLVKLGKAYKYIVTCAVVQKSAYGFHTASSCFWDTTSDGTCTVRWENRTMNCIVNVFAIAIVL
uniprot
proteins
function
FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
13062
uniprot
proteins
protein_family
Dynein light chain Tctex-type family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16079286
uniprot
proteins
pubmed
17289665
uniprot
proteins
pubmed
8004092
uniprot
proteins
sequence_length
116
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Note=Colocalizes with BUB3 at kinetochores specifically during prometaphase.
uniprot
proteins