FBXL22
entrez
283807
canonical
uniprot
Q6P050
canonical
ensembl
ENSG00000197361
resolver
ensp
ENSP00000353794
resolver
ensp
ENSP00000453697
resolver
ensp
ENSP00000492359
resolver
ensp
ENSP00000796482
resolver
enst
ENST00000534939
resolver
genesymbol
FBXL22
resolver
hgnc
HGNC:27537
resolver
uniprot
A0A1W2PQW8
resolver
uniprot
H0YMQ4
resolver
uniprot_entry
FXL22_HUMAN
resolver
uniprot_entry
H0YMQ4_HUMAN
resolver
uniprot_sec
A0A1W2PQW8
resolver
amino_acid_sequence
MWPLLTMHITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQKDNFLLGPALRSLSICWHSSRVQVCSIEDWLKSAFQRSICSRHESLVNDFLLRVCDRCPNLASVTLSGCGHVTDDCLARLLRCCPRLRALRLENCARVTNRTLAAVAADGRALQTLHVDFCRNVSAAGLRRLRAACPRLALRAEHSAAMLPDQPPRPRAPAAALGKLLQR
uniprot
proteins
function
FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC). {ECO:0000269|PubMed:22972877}.
uniprot
proteins
mass_dalton
26028
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:22972877}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15520277
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
22972877
uniprot
proteins
sequence_length
231
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:22972877}.
uniprot
proteins