Elp5
entrez
287446
canonical
uniprot
Q6IUP3
canonical
ensembl
ENSRNOG00000027628
resolver
ensp
ENSRNOP00000035345
resolver
enst
ENSRNOT00000032481
resolver
genesymbol
Elp5
resolver
genesymbol_syn
Derp6
resolver
genesymbol_syn
Rai12
resolver
uniprot
A0A0H2UHU6
resolver
uniprot
B0BMU7
resolver
uniprot_entry
A0A0H2UHU6_RAT
resolver
uniprot_entry
B0BMU7_RAT
resolver
uniprot_entry
ELP5_RAT
resolver
amino_acid_sequence
MPRLLSGDDIRRRPEASEMLDSLLATGGLVLLRDSVEWEGRGLLKALIKKSALRGEQVHVLGCEVSEEEFREGLGSDVNSRLVYHDLFRDPLNWSQPGEAAPEGPLKALRSMCRRTDRGSVTIALDSLSWLLCHIPCVTLCQALHALSQRNVDPGDNPLIEQVRVLGLLHEELHGPGPVGAVSSLAHTEVTLSGKMDQTSASILCRRPQQRATYQTWWFSILPDFSLDLHEGLPLHSELHRDPHTTQVDPASHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLHPVPGQTTGRIFYEPDAFDDVDQEDPDDDLDI
uniprot
proteins
function
FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Involved in cell migration (By similarity). {ECO:0000250|UniProtKB:Q8TE02, ECO:0000250|UniProtKB:Q99L85}.
uniprot
proteins
mass_dalton
35490
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. {ECO:0000250|UniProtKB:Q8TE02}.
uniprot
proteins
post_translational_modification
PTM: Tyrosine-phosphorylated. {ECO:0000250|UniProtKB:Q8TE02}.
uniprot
proteins
protein_family
ELP5 family
uniprot
proteins
sequence_length
318
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8TE02}. Cytoplasm {ECO:0000250|UniProtKB:Q8TE02}.
uniprot
proteins