Actg2
entrez
25365
canonical
uniprot
P63269
canonical
ensembl
ENSRNOG00055012722
resolver
ensembl
ENSRNOG00060003018
resolver
ensembl
ENSRNOG00065016044
resolver
ensp
ENSRNOP00055017652
resolver
ensp
ENSRNOP00060003661
resolver
ensp
ENSRNOP00065020971
resolver
enst
ENSRNOT00055021770
resolver
enst
ENSRNOT00060005006
resolver
enst
ENSRNOT00065026723
resolver
genesymbol
Actg2
resolver
genesymbol_syn
Acta3
resolver
genesymbol_syn
Actsg
resolver
uniprot
P12718
resolver
uniprot_entry
ACTH_RAT
resolver
uniprot_sec
P12718
resolver
amino_acid_sequence
MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
uniprot
proteins
mass_dalton
41877
uniprot
proteins
post_translational_modification
PTM: [Actin, gamma-enteric smooth muscle, intermediate form]: N-terminal cleavage of acetylated cysteine of intermediate muscle actin by ACTMAP. {ECO:0000250|UniProtKB:P62737}.; PTM: Oxidation of Met-45 and Met-48 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization. {ECO:0000250|UniProtKB:P63268}.; PTM: Monomethylation at Lys-85 (K85me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. {ECO:0000250|UniProtKB:P68133}.; PTM: Methylated at His-74 by SETD3. {ECO:0000250|UniProtKB:P63267}.
uniprot
proteins
protein_family
Actin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
3244353
uniprot
proteins
sequence_length
376
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
uniprot
proteins