Slx1b
entrez
293489
canonical
uniprot
Q5PQP5
canonical
ensembl
ENSRNOG00000019369
resolver
ensembl
ENSRNOG00055026131
resolver
ensembl
ENSRNOG00060030907
resolver
ensembl
ENSRNOG00065016765
resolver
ensp
ENSRNOP00000026231
resolver
ensp
ENSRNOP00055036999
resolver
ensp
ENSRNOP00060044553
resolver
ensp
ENSRNOP00065022086
resolver
enst
ENSRNOT00000026231
resolver
enst
ENSRNOT00055045109
resolver
enst
ENSRNOT00060053673
resolver
enst
ENSRNOT00065027968
resolver
genesymbol
Slx1b
resolver
genesymbol_syn
Giyd1
resolver
genesymbol_syn
Giyd2
resolver
genesymbol_syn
Slx1
resolver
uniprot_entry
SLX1_RAT
resolver
amino_acid_sequence
MGHAARPGRFFGVYLLYCQNPRHRGRVYVGFTVNPARRVRQHNAGRKKGGAWRTSGRGPWDMVLILHGFPSAVAALRFEWAWQHPQASRRLTHVGPRLRSEASFTFHLRVLAHMLRVPPWVRLPLTVRWLRPDFRHELCPAPPPHMPIAFGPPPPQPLVPKRPAASEADSERRLDLGAKASCTLCARMLQDEEGPLCCPHPGCPLRAHIICLAEEFLQEEPGQLLPLEGHCPSCKKSLLWGNLVGQCHEDTEEEEVDLELEEEHWTDLLET
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. {ECO:0000255|HAMAP-Rule:MF_03100}.
uniprot
proteins
mass_dalton
30746
uniprot
proteins
protein_family
SLX1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|HAMAP-Rule:MF_03100}.
uniprot
proteins