CUZD1
entrez
50624
canonical
uniprot
Q86UP6
canonical
ensembl
ENSG00000138161
resolver
ensp
ENSP00000376540
resolver
genesymbol
CUZD1
resolver
hgnc
HGNC:17937
resolver
uniprot
A8K080
resolver
uniprot
B2RN93
resolver
uniprot
D3DRE5
resolver
uniprot
Q7Z660
resolver
uniprot
Q7Z661
resolver
uniprot
Q86SG1
resolver
uniprot
Q86UP5
resolver
uniprot
Q9HAR7
resolver
uniprot_entry
CUZD1_HUMAN
resolver
uniprot_sec
A8K080
resolver
uniprot_sec
B2RN93
resolver
uniprot_sec
D3DRE5
resolver
uniprot_sec
Q7Z660
resolver
uniprot_sec
Q7Z661
resolver
uniprot_sec
Q86SG1
resolver
uniprot_sec
Q86UP5
resolver
uniprot_sec
Q9HAR7
resolver
amino_acid_sequence
MELVRRLMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSNVVEFSVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYITEDDVIQSQNALGKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTSDPNLVVFLDTCRASPTSDFASPTYDLIKSGCSRDETCKVYPLFGHYGRFQFNAFKFLRSMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLKRDRSASGNSGFQHETHAEETPNQPFNSVHLFSFMVLALNVVTVATITVRHFVNQRADYKYQKLQNY
uniprot
proteins
function
FUNCTION: Localized to zymogen granules, where it functions in trypsinogen activation (By similarity). May indirectly regulate cell motility, cell-cell and cell/extracellular matrix interactions (PubMed:15184879). {ECO:0000250|UniProtKB:P70412, ECO:0000269|PubMed:15184879}.
uniprot
proteins
mass_dalton
68153
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15184879
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
607
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Zymogen granule membrane {ECO:0000250|UniProtKB:P70412}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P70412}.
uniprot
proteins
transmembrane_region
TRANSMEM 569..589; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins