Q8R5K6
uniprot
Q8R5K6
canonical
amino_acid_sequence
MQLEIQVALNFIISYLYNKLPRRRVNIFGEELERLLKQKYEGHWYPEKPYKGSGFRCIHVGEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVKVLYVDDSNENGCELDKEIKNSFNPEAQVFMPISDPASSVSSSPSPPFGHSAAVSPTFMPRSTQPLTFTTATFAATKFGSTKMKNSGRSSKVARTSPISLGLNVNVNDLLKQKAISSSMHSLYGLGLGSQQQPQPQPQQPPSQPPPPPPPPQQQQQHQQQQQQQQQQQQQPQQQTSALSPNAKEFIFPNMQGQGSSTNGMFPGDSPLNLSPLQYSNAFNVFAAYGGLNEKSFVDGLNFSLNNIQYSNQQFQPVMAN
uniprot
proteins
function
FUNCTION: Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay. {ECO:0000250|UniProtKB:P50616}.
uniprot
proteins
mass_dalton
40461
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on Ser and Thr residues. {ECO:0000250}.
uniprot
proteins
protein_family
BTG family
uniprot
proteins
pubmed
21336257
uniprot
proteins
sequence_length
365
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic. {ECO:0000250}.
uniprot
proteins