Alox5ap
entrez
29624
canonical
uniprot
P20291
canonical
ensembl
ENSRNOG00000000907
resolver
ensembl
ENSRNOG00055003427
resolver
ensembl
ENSRNOG00060002388
resolver
ensembl
ENSRNOG00065006327
resolver
ensp
ENSRNOP00000001207
resolver
ensp
ENSRNOP00055003946
resolver
ensp
ENSRNOP00060002634
resolver
ensp
ENSRNOP00065007016
resolver
enst
ENSRNOT00000001207
resolver
enst
ENSRNOT00055005320
resolver
enst
ENSRNOT00060003776
resolver
enst
ENSRNOT00065009709
resolver
genesymbol
Alox5ap
resolver
genesymbol_syn
Flap
resolver
uniprot
Q5RJL3
resolver
uniprot_entry
AL5AP_RAT
resolver
uniprot_sec
Q5RJL3
resolver
amino_acid_sequence
MDQEAVGNVVLLAIVTLISVVQNAFFAHKVELESKAQSGRSFQRTGTLAFERVYTANQNCVDAYPTFLVVLWTAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSLAGILNHYLIFFFGSDFENYIRTITTTISPLLLIP
uniprot
proteins
function
FUNCTION: Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
18070
uniprot
proteins
protein_family
MAPEG family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2300172
uniprot
proteins
pubmed
2300173
uniprot
proteins
sequence_length
161
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..30; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 53..77; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 81..102; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 116..128; /note="Helical"; /evidence="ECO:0000250
uniprot
proteins