B0L3A2
uniprot
B0L3A2
canonical
amino_acid_sequence
MTMFKGSNEMKSRWNWGSITCIICFTCVGSQLSMSSSKASNFSGPLQLYQRELEIFIVLTDVPNYRLIKENSHLHTTIVDQGRTV
uniprot
proteins
function
FUNCTION: Dual receptor for both endothelin-1 and the signal sequence of vascular endothelial growth factor A (PubMed:17446437, PubMed:24465725). Does not act as a receptor for angiotensin-2 (PubMed:17446437). Does not bind the VEGFA mature protein (By similarity). May play a role in angiogenesis with a significant role in cardiovascular and neural development (By similarity). {ECO:0000250|UniProtKB:Q2QKR2, ECO:0000269|PubMed:17446437, ECO:0000269|PubMed:24465725}.
uniprot
proteins
mass_dalton
9677
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:27301377}.
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17446437
uniprot
proteins
pubmed
24465725
uniprot
proteins
pubmed
27301377
uniprot
proteins
pubmed
33853558
uniprot
proteins
sequence_length
85
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24465725, ECO:0000269|PubMed:27301377, ECO:0000269|PubMed:33853558}; Single-pass membrane protein {ECO:0000305|PubMed:27301377}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..37; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins