TIMM17A
entrez
10440
canonical
uniprot
Q99595
canonical
ensembl
ENSG00000134375
resolver
ensp
ENSP00000356256
resolver
enst
ENST00000367287
resolver
genesymbol
TIMM17A
resolver
genesymbol_syn
MIMT17
resolver
genesymbol_syn
TIM17
resolver
genesymbol_syn
TIM17A
resolver
genesymbol_syn
TIMM17
resolver
hgnc
HGNC:17315
resolver
uniprot
B2RDM5
resolver
uniprot
Q9BWF5
resolver
uniprot_entry
TI17A_HUMAN
resolver
uniprot_sec
B2RDM5
resolver
uniprot_sec
Q9BWF5
resolver
amino_acid_sequence
MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAIKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSFAVWGGLFSMIDCSMVQVRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFASAQFPNGPQFAEDPSQLPSTQLPSSPFGDYRQYQ
uniprot
proteins
function
FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. {ECO:0000269|PubMed:10339406}.
uniprot
proteins
mass_dalton
18024
uniprot
proteins
post_translational_modification
PTM: Degraded by YMEL1 downstream of the integrated stress response (ISR). {ECO:0000269|PubMed:24315374}.
uniprot
proteins
protein_family
Tim17/Tim22/Tim23 family
uniprot
proteins
pubmed
10339406
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23263864
uniprot
proteins
pubmed
24315374
uniprot
proteins
pubmed
8893850
uniprot
proteins
sequence_length
171
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:10339406}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..37; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 63..77; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 113..133; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins