Abhd11
entrez
68758
canonical
uniprot
Q8K4F5
canonical
ensembl
ENSMUSG00000040532
resolver
ensp
ENSMUSP00000043041
resolver
ensp
ENSMUSP00000106847
resolver
ensp
ENSMUSP00000144449
resolver
enst
ENSMUST00000046999
resolver
enst
ENSMUST00000111216
resolver
enst
ENSMUST00000154469
resolver
genesymbol
Abhd11
resolver
genesymbol_syn
Wbscr21
resolver
uniprot
D3YYK0
resolver
uniprot_entry
ABHDB_MOUSE
resolver
uniprot_entry
D3YYK0_MOUSE
resolver
amino_acid_sequence
MLRWARAWRVPRGVLGASSPRRLAVPVTFCSSRSSGQENADLRPLPLSYNLLDGDATLPAIVFLHGLFGSKTNFNSLAKAMVQRTGRRVLTVDARNHGDSPHSPDASYEAMSQDLQGLLPQLGLVPCVLVGHSMGGKTAMLLALQRPDVVERLVVVDISPVGTTPGSHIGAFIAAMKAVEIPEKVPHSQARKLADKQLSSVVKEAGIRQFLLTNLVEVGGRFSWRLNLDTLAQHLDKIMTFPQQREPYSGPTLFLLGGNSTYVQPSHHSEIRRLFPQAQIQTVPNAGHWVHSDKPQDFMDAVTSFLA
uniprot
proteins
ec_number
3.1.1.116
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of diacylglycerol in vitro and may function as a key regulator in lipid metabolism, namely by regulating the intracellular levels of diacylglycerol (By similarity). 1,2-diacyl-sn-glycerols are the preferred substrate over 1,3-diacyl-sn-glycerols. The enzyme hydrolyzes stearate in preference to palmitate from the sn-1 position of 1,2-diacyl-sn-glycerols (By similarity). Maintains the functional lipoylation of the 2-oxoglutarate dehydrogenase complex (OGDHc) through its interaction with the OGDHc by preventing the formation of lipoyl adducts (By similarity). In addition, is also required for the expansion and differentiation of embryonic stem cells (ESCs) (PubMed:32733886). {ECO:0000250|UniProtKB:Q3SZ73, ECO:0000250|UniProtKB:Q8NFV4, ECO:0000269|PubMed:32733886}.
uniprot
proteins
mass_dalton
33561
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250|UniProtKB:Q3SZ73}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
pubmed
12073013
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17215164
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
32579589
uniprot
proteins
pubmed
32733886
uniprot
proteins
sequence_length
307
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:32579589}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q8NFV4}.
uniprot
proteins