Abhd18
entrez
269423
canonical
uniprot
Q8C1A9
canonical
ensembl
ENSMUSG00000037818
resolver
ensp
ENSMUSP00000124430
resolver
genesymbol
Abhd18
resolver
uniprot
Q3TQS7
resolver
uniprot
Q562E0
resolver
uniprot
Q8C0I3
resolver
uniprot_entry
ABD18_MOUSE
resolver
uniprot_sec
Q3TQS7
resolver
uniprot_sec
Q562E0
resolver
uniprot_sec
Q8C0I3
resolver
amino_acid_sequence
MGVSKLDILYRRLLLTKLFIRGWGRPEDLKRLFEFRKMIGNRERCQNLVSSDYPVHIDKVEEQSDCKILDGHFVSPMAHYVPGIMPIESVVARFQFIVPKEWNSRYRPVCIHLAGTGDHHYWRRRTLMARPMIKEARMASLLLENPYYGCRKPKDQVRSSLKNVSDLFVMGGALILESAALLHWLEREGYGPLGMTGISMGGHMASLAVSNWPKPMPLIPCLSWSTASGVFTTGVLSKSINWRELEKQYYTQTVYEEEIIHMLEYCGTDSFKMGHEFMNHLPSNADKLTNLNLVSRTLNLDMTDQVVSPKDAKCHKSGKTSISAPSNGQLLQDTAKMECLNQTLSTNKSWFASYNPQSFHLLNREQRRSNRQKESLIFMKGVMDECTHVANFSVPVDPSLIIVVQAKEDAYIPRTGVRSLQEIWPGCEIRYLEGGHISAYLFKQGLFRQAIYDAFERFLHKYAN
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of an acyl chain from the tetra-acylated cardiolipin (CL) and produces the tri-acylated monolysocardiolipin (MLCL). Prefers CL with shorter and saturated fatty acyl chains as substrates. Together with Tafazzin (TAZ), it participates in the mechanism of CL remodeling, a process consisting of repetitive cycles of hydrolysis and reacylation of the fatty acids that make up CL, where the nascent acyl chains are replaced with longer, unsaturated chains. {ECO:0000250|UniProtKB:Q0P651}.
uniprot
proteins
mass_dalton
53168
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
40378955
uniprot
proteins
pubmed
40903572
uniprot
proteins
sequence_length
464
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q0P651}.
uniprot
proteins