Ncdn
entrez
26562
canonical
uniprot
Q9Z0E0
canonical
ensembl
ENSMUSG00000028833
resolver
ensp
ENSMUSP00000030637
resolver
ensp
ENSMUSP00000101722
resolver
ensp
ENSMUSP00000247630
resolver
genesymbol
Ncdn
resolver
genesymbol_syn
Kiaa0607
resolver
genesymbol_syn
Sfap75
resolver
uniprot
Q3TCW4
resolver
uniprot
Q80TW1
resolver
uniprot
Q91YH7
resolver
uniprot
Q9CW81
resolver
uniprot
Q9QUQ0
resolver
uniprot_entry
NCDN_MOUSE
resolver
uniprot_sec
Q3TCW4
resolver
uniprot_sec
Q80TW1
resolver
uniprot_sec
Q91YH7
resolver
uniprot_sec
Q9CW81
resolver
uniprot_sec
Q9QUQ0
resolver
amino_acid_sequence
MSCCDLAAAGQLGKAGIMASDCEPALNQAESRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELASHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQRAEDASKFELCQLLPLFLPPTTVPPECHRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPVGSSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSIMKEAIGAVIHYLLQVGPEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEASDISQQVANLAISPTTPGPSWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPSLVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQAVLALSPDYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP
uniprot
proteins
function
FUNCTION: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth. {ECO:0000269|PubMed:15790563, ECO:0000269|PubMed:18572016, ECO:0000269|PubMed:20007903}.
uniprot
proteins
mass_dalton
78895
uniprot
proteins
post_translational_modification
PTM: Palmitoylated. Palmitoylation by ZDHHC1, ZDHHC3 and ZDHHC11 regulates the association of NCDN with endosome membranes. May also be palmitoylated by ZDHHC7. {ECO:0000250|UniProtKB:O35095}.
uniprot
proteins
protein_family
Neurochondrin family
uniprot
proteins
pubmed
10231559
uniprot
proteins
pubmed
11162505
uniprot
proteins
pubmed
11445285
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
14559245
uniprot
proteins
pubmed
15007648
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15790563
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18572016
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20007903
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
729
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35095}. Endosome membrane {ECO:0000250|UniProtKB:O35095}; Lipid-anchor {ECO:0000250|UniProtKB:O35095}. Cell projection, dendrite {ECO:0000250|UniProtKB:O35095}. Postsynapse {ECO:0000250|UniProtKB:O35095}. Note=Localizes to somatic regions of neurons. Localization to endosome membrane requires palmitoylation. {ECO:0000250|UniProtKB:O35095}.
uniprot
proteins