Q64202
uniprot
Q64202
canonical
amino_acid_sequence
KLMKQGGAALEGSALANGRALSAGSPPVPPGWNRIPPLGRAQEE
uniprot
proteins
function
FUNCTION: Plays a role as a transcriptional activator or repressor. Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation. Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. {ECO:0000250|UniProtKB:P56177, ECO:0000250|UniProtKB:Q64317}.
uniprot
proteins
mass_dalton
4451
uniprot
proteins
protein_family
Distal-less homeobox family
uniprot
proteins
pubmed
8613727
uniprot
proteins
sequence_length
44
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P56177}.
uniprot
proteins