SH2D4A
entrez
63898
canonical
uniprot
Q9H788
canonical
ensembl
ENSG00000104611
resolver
ensp
ENSP00000265807
resolver
ensp
ENSP00000428684
resolver
ensp
ENSP00000429482
resolver
ensp
ENSP00000574001
resolver
genesymbol
SH2D4A
resolver
genesymbol_syn
PPP1R38
resolver
genesymbol_syn
SH2A
resolver
hgnc
HGNC:26102
resolver
uniprot
B4DDR1
resolver
uniprot
Q5XKC1
resolver
uniprot
Q6NXE9
resolver
uniprot
Q86YM2
resolver
uniprot
Q96C88
resolver
uniprot
Q9H7F7
resolver
uniprot_entry
SH24A_HUMAN
resolver
uniprot_sec
B4DDR1
resolver
uniprot_sec
Q5XKC1
resolver
uniprot_sec
Q6NXE9
resolver
uniprot_sec
Q86YM2
resolver
uniprot_sec
Q96C88
resolver
uniprot_sec
Q9H7F7
resolver
amino_acid_sequence
MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
uniprot
proteins
function
FUNCTION: Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. {ECO:0000269|PubMed:18641339, ECO:0000269|PubMed:19712589}.
uniprot
proteins
mass_dalton
52727
uniprot
proteins
pubmed
12476414
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18641339
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19712589
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
454
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18641339}. Note=Located at podocyte foot processes. {ECO:0000250}.
uniprot
proteins