Ing3
entrez
312154
canonical
uniprot
Q498T3
canonical
ensembl
ENSRNOG00000005496
resolver
ensembl
ENSRNOG00055021181
resolver
ensembl
ENSRNOG00060019752
resolver
ensembl
ENSRNOG00065007632
resolver
ensp
ENSRNOP00000007476
resolver
ensp
ENSRNOP00000088161
resolver
ensp
ENSRNOP00055029406
resolver
ensp
ENSRNOP00060027951
resolver
ensp
ENSRNOP00065008713
resolver
enst
ENSRNOT00000104929
resolver
enst
ENSRNOT00055036195
resolver
enst
ENSRNOT00060034111
resolver
enst
ENSRNOT00065011950
resolver
genesymbol
Ing3
resolver
uniprot_entry
ING3_RAT
resolver
amino_acid_sequence
MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQPVNNHHAHSHTPVEKRKYNPTSHHTATDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCNNAYNVNSSQPLASYNIGSLSSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMPRETAGYSSSSALMTTLTQNASSSAADSRSGRKSKNNTKSSSQQSSSSSSSSSSSSLSLCSSSSTVVQEVSQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQCTAAMKRRGSRHK
uniprot
proteins
function
FUNCTION: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
46925
uniprot
proteins
protein_family
ING family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
421
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins