CEACAM16
entrez
388551
canonical
uniprot
Q2WEN9
canonical
ensembl
ENSG00000213892
resolver
ensp
ENSP00000385576
resolver
ensp
ENSP00000466561
resolver
enst
ENST00000405314
resolver
enst
ENST00000587331
resolver
genesymbol
CEACAM16
resolver
genesymbol_syn
CEAL2
resolver
hgnc
HGNC:31948
resolver
uniprot
A7LI12
resolver
uniprot_entry
CEA16_HUMAN
resolver
uniprot_sec
A7LI12
resolver
amino_acid_sequence
MALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAAVATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAPLG
uniprot
proteins
disease_involvement
DISEASE: Deafness, autosomal dominant, 4B (DFNA4B) [MIM:614614]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. {ECO:0000269|PubMed:21368133, ECO:0000269|PubMed:25589040}. Note=The disease is caused by variants affecting the gene represented in this entry.; DISEASE: Deafness, autosomal recessive, 113 (DFNB113) [MIM:618410]: A form of non-syndromic, sensorineural deafness characterized by postlingual progressive hearing impairment. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. {ECO:0000269|PubMed:29703829}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. {ECO:0000269|PubMed:21368133, ECO:0000269|PubMed:25589040, ECO:0000269|PubMed:29703829}.
uniprot
proteins
mass_dalton
45873
uniprot
proteins
protein_family
CEA family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21368133
uniprot
proteins
pubmed
25589040
uniprot
proteins
pubmed
29703829
uniprot
proteins
sequence_length
425
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:25589040}. Note=Localizes to the tip of cochlear outer hair cells and to the tectorial membrane. {ECO:0000250|UniProtKB:E9QA28}.
uniprot
proteins