Hk3
entrez
25060
canonical
uniprot
P27926
canonical
ensembl
ENSRNOG00000026235
resolver
ensp
ENSRNOP00000031587
resolver
enst
ENSRNOT00000031935
resolver
genesymbol
Hk3
resolver
uniprot
A0A0G2JST6
resolver
uniprot
Q497A1
resolver
uniprot_entry
A0A0G2JST6_RAT
resolver
uniprot_entry
HXK3_RAT
resolver
uniprot_sec
Q497A1
resolver
activity_regulation
ACTIVITY REGULATION: Hexokinase is an allosteric enzyme inhibited by its product D-glucose 6-phosphate. {ECO:0000250|UniProtKB:P52790}.
uniprot
proteins
amino_acid_sequence
MAAIEPSGLHPGERDSSCPQEGIPRPSGSLELAQEYLQQFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKEHSVETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNIDVVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGVLFGGCASPALLSQNSILLEHVAKMEDPATGIAHVHTVLQGLGLSPQASDAELVQRVCMAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETVMLLAPECDVSFIPSVDGGGRGVAMVTAVAARLATHRRILEETLAPFQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEGSVQITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLSGQSLPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTVGTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPGDSGHMCINMEWGAFGDDGSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQCLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLTLTSDDALMVLEVCQAVSRRAAQLCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTVRKLAPQCTVTFLQSEDGSGKGAALVTRVACRLTQMACV
uniprot
proteins
ec_number
2.7.1.1
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:5871820). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:5871820). {ECO:0000269|PubMed:5871820}.
uniprot
proteins
mass_dalton
100254
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; hexose metabolism. {ECO:0000305|PubMed:5871820}.; PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4. {ECO:0000305|PubMed:5871820}.
uniprot
proteins
protein_family
Hexokinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1897938
uniprot
proteins
pubmed
5871820
uniprot
proteins
pubmed
7044667
uniprot
proteins
sequence_length
924
uniprot
proteins