Rgs6
entrez
50779
canonical
uniprot
Q9Z2H2
canonical
ensembl
ENSMUSG00000021219
resolver
ensp
ENSMUSP00000125256
resolver
ensp
ENSMUSP00000139566
resolver
ensp
ENSMUSP00000139735
resolver
ensp
ENSMUSP00000140701
resolver
ensp
ENSMUSP00000143801
resolver
ensp
ENSMUSP00000143961
resolver
enst
ENSMUST00000161801
resolver
enst
ENSMUST00000185665
resolver
enst
ENSMUST00000186309
resolver
enst
ENSMUST00000186458
resolver
enst
ENSMUST00000200911
resolver
enst
ENSMUST00000202210
resolver
genesymbol
Rgs6
resolver
uniprot
A0A087WNZ9
resolver
uniprot
A0A087WRN0
resolver
uniprot
A0ACM8Q8I7
resolver
uniprot
B1B1E4
resolver
uniprot
Q08AT5
resolver
uniprot
Q3UTM5
resolver
uniprot
Q8BGI8
resolver
uniprot_entry
A0A087WNZ9_MOUSE
resolver
uniprot_entry
A0ACM8Q8I7_MOUSE
resolver
uniprot_entry
Q3UTM5_MOUSE
resolver
uniprot_entry
RGS6_MOUSE
resolver
uniprot_sec
A0A087WRN0
resolver
uniprot_sec
B1B1E4
resolver
uniprot_sec
Q08AT5
resolver
uniprot_sec
Q8BGI8
resolver
amino_acid_sequence
MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS
uniprot
proteins
function
FUNCTION: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity. {ECO:0000250|UniProtKB:P49758}.
uniprot
proteins
mass_dalton
54531
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15632198
uniprot
proteins
pubmed
15897264
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
472
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15897264}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P49758}. Membrane {ECO:0000250|UniProtKB:P49758}; Peripheral membrane protein {ECO:0000250|UniProtKB:P49758}. Nucleus {ECO:0000250|UniProtKB:P49758}. Cell membrane {ECO:0000269|PubMed:15897264}. Note=Interaction with GNB5 mediates translocation to the nucleus. {ECO:0000250|UniProtKB:P49758}.
uniprot
proteins