Slc24a2
entrez
76376
canonical
uniprot
Q8BUN9
canonical
ensembl
ENSMUSG00000037996
resolver
ensp
ENSMUSP00000102775
resolver
ensp
ENSMUSP00000102776
resolver
ensp
ENSMUSP00000216826
resolver
ensp
ENSMUSP00000216827
resolver
ensp
ENSMUSP00000216828
resolver
ensp
ENSMUSP00000216829
resolver
ensp
ENSMUSP00000216830
resolver
ensp
ENSMUSP00000216831
resolver
ensp
ENSMUSP00000216833
resolver
ensp
ENSMUSP00000216834
resolver
ensp
ENSMUSP00000216835
resolver
ensp
ENSMUSP00000216836
resolver
ensp
ENSMUSP00000216838
resolver
ensp
ENSMUSP00000216839
resolver
ensp
ENSMUSP00000216841
resolver
genesymbol
Slc24a2
resolver
uniprot
B1AXF2
resolver
uniprot
B1AXF3
resolver
uniprot
Q14AY1
resolver
uniprot
Q14BI1
resolver
uniprot_entry
NCKX2_MOUSE
resolver
uniprot_sec
B1AXF2
resolver
uniprot_sec
B1AXF3
resolver
uniprot_sec
Q14AY1
resolver
uniprot_sec
Q14BI1
resolver
amino_acid_sequence
MDLHQSPTARLLQKWCSHESPFGCRRHYNSRKKLKLIRVIGLVMGLVAVSTVPFSISAFTETDSQSNRGEASDMSGPRVAQGHRQRTLLDLNDKIRDYTPQPPASQEDQAENSTEHTQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLLMLITFFLDNVIMWWESLLLLTAYFAYVVFMKFNVQVERWVKQMISRNNVIKVTVPEAQAKSPTAGDKDGPTLPSKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKKKCQVDENERQNGAANHVEKIELPNSTSTEVEMTPSSEASEPVQNGNLSHNIEAADAPKATETAEEEDDQPLSLSWPTNTRKQATFLIVFPIVFPLWITLPDVRKPASRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTIIHRFSPVTVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDKVLVCPVSI
uniprot
proteins
function
FUNCTION: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (By similarity). Required for learming and memory by regulating neuronal Ca(2+), which is essential for the development of synaptic plasticity (PubMed:16407245). {ECO:0000250|UniProtKB:Q9UI40, ECO:0000269|PubMed:16407245}.
uniprot
proteins
mass_dalton
74241
uniprot
proteins
protein_family
Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family
uniprot
proteins
protein_family
SLC24A subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16407245
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
666
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9UI40}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 134..154; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 180..200; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 206..226; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 238..258; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 503..523; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 539..559; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 575..595; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 608..628; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 636..656; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins