SPACA3
entrez
124912
canonical
uniprot
Q8IXA5
canonical
ensembl
ENSG00000141316
resolver
ensp
ENSP00000269053
resolver
ensp
ENSP00000378134
resolver
enst
ENST00000394638
resolver
genesymbol
SPACA3
resolver
genesymbol_syn
LYC3
resolver
genesymbol_syn
LYZL3
resolver
genesymbol_syn
SLLP1
resolver
genesymbol_syn
SPRASA
resolver
hgnc
HGNC:16260
resolver
uniprot
E9PBS7
resolver
uniprot
E9PF91
resolver
uniprot
Q05C28
resolver
uniprot
Q7Z4Y5
resolver
uniprot_entry
E9PF91_HUMAN
resolver
uniprot_entry
Q05C28_HUMAN
resolver
uniprot_entry
SACA3_HUMAN
resolver
uniprot_sec
E9PBS7
resolver
uniprot_sec
Q7Z4Y5
resolver
amino_acid_sequence
MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALSQSGGGSTSAAGIEARSRALRRRWCPAGIMLLALVCLLSCLLPSSEAKLYGRCELARVLHDFGLDGYRGYSLADWVCLAYFTSGFNAAALDYEADGSTNNGIFQINSRRWCSNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHHCQGKDLTEWVDGCDF
uniprot
proteins
function
FUNCTION: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro. {ECO:0000269|PubMed:12606493}.
uniprot
proteins
mass_dalton
23431
uniprot
proteins
post_translational_modification
PTM: The processed form derives from the membrane form by proteolytic processing.
uniprot
proteins
protein_family
Glycosyl hydrolase 22 family
uniprot
proteins
pubmed
12606493
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14747161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16014814
uniprot
proteins
sequence_length
215
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 64..84; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins