Pon3
entrez
312086
canonical
uniprot
Q68FP2
canonical
genesymbol
Pon3
resolver
uniprot_entry
PON3_RAT
resolver
amino_acid_sequence
MGKLVALTVLGASLALLGERLLNFRERVSTSREIKPTEPQNCHLIEGLENGSEDIDILPSGLAFISTGLKYPGMPSFAPDKPGRIFLMDLNEPYPKAQALEISDGFDQDSLNPHGISTFIDKDNTVYLYAVNHPHMDSTVEIFKFEEQPRSLVHLKTIKHELFESVNDIVVLGPEQFYATRDHYFTSHFLVLLEMILDPHWTSVLFYSPKEVKVVAQGFSSANGITVSLDQKYVYVADVTAKNIHIMKKHNNWDLTPVKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLIYNPEDPPGSEVLRIQDPLSDNPRVSTLYSNNGSVLQGSTVASVYHKKMLIGTIFHKALYCEL
uniprot
proteins
ec_number
3.1.1.2
uniprot
proteins
ec_number
3.1.1.81
uniprot
proteins
ec_number
3.1.8.1
uniprot
proteins
function
FUNCTION: Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
39458
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250}.; PTM: The signal sequence is not cleaved. {ECO:0000250}.
uniprot
proteins
protein_family
Paraoxonase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
354
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000250}.
uniprot
proteins