Sepsecs
entrez
211006
canonical
uniprot
Q6P6M7
canonical
ensembl
ENSMUSG00000029173
resolver
ensp
ENSMUSP00000031069
resolver
ensp
ENSMUSP00000206066
resolver
enst
ENSMUST00000031069
resolver
genesymbol
Sepsecs
resolver
genesymbol_syn
D5Ertd135e
resolver
uniprot
Q3U597
resolver
uniprot
Q8BZS6
resolver
uniprot_entry
Q3U597_MOUSE
resolver
uniprot_entry
SPCS_MOUSE
resolver
uniprot_sec
Q8BZS6
resolver
amino_acid_sequence
MNPESFAAGERRVSPAYVRQGCEARRAHEHLIRLLLEQGKCPEDGWDESTLELFLHELAVMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSGDISAVQPKAAGSSLLNKITNSLVLNVIKLAGVHSVASCFVVPMATGMSLTLCFLTLRHKRPKAKYIIWPRIDQKSCFKSMVTAGFEPVVIENVLEGDELRTDLKAVEAKIQELGPEHILCLHSTTACFAPRVPDRLEELAVICANYDIPHVVNNAYGLQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFNEPFIQDISKMYPGRASASPSLDVLITLLSLGCSGYRKLLKERKEMFVYLSTQLKKLAEAHNERLLQTPHNPISLAMTLKTIDGHHDKAVTQLGSMLFTRQVSGARAVPLGNVQTVSGHTFRGFMSHADNYPCAYLNAAAAIGMKMQDVDLFIKRLDKCLNIVRKEQTRASVVSGADRNKAEDADIEEMALKLDDVLGDVGQGPAL
uniprot
proteins
ec_number
2.9.1.2
uniprot
proteins
function
FUNCTION: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. {ECO:0000269|PubMed:16230358, ECO:0000269|PubMed:17194211}.
uniprot
proteins
mass_dalton
55326
uniprot
proteins
mutagenesis
MUTAGEN 105; /note="Q->E: 50% of wild-type activity."; /evidence="ECO:0000269|PubMed:18093968"; MUTAGEN 313; /note="R->E: Virtually inactive."; /evidence="ECO:0000269|PubMed:18093968"; MUTAGEN 313; /note="R->S: 30% of wild-type activity."; /evidence="ECO:0000269|PubMed:18093968
uniprot
proteins
pathway_participation
PATHWAY: Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2. {ECO:0000269|PubMed:16230358, ECO:0000269|PubMed:17194211}.
uniprot
proteins
protein_family
SepSecS family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16230358
uniprot
proteins
pubmed
17194211
uniprot
proteins
pubmed
18093968
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
504
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9HD40}.
uniprot
proteins