Slc25a36
entrez
192287
canonical
uniprot
Q922G0
canonical
ensembl
ENSMUSG00000032449
resolver
ensp
ENSMUSP00000082302
resolver
enst
ENSMUST00000085206
resolver
genesymbol
Slc25a36
resolver
uniprot_entry
S2536_MOUSE
resolver
amino_acid_sequence
MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKAILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNGVFDPDSTQVHMASAAMAGFTAITATNPIWLIKTRLQLDARTRGEKQMGAFECVRKVYQTDGLRGFYRGMSASYAGISETVIHFVIYESIKQKLLECKTASMMETDEESVKEASDFVRMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLIVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
uniprot
proteins
function
FUNCTION: Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Selectively transports cytosine, guanosine, inosine and uridine (deoxy)nucleoside mono-, di-, and triphosphates by antiport mechanism. Catalyzes uniport at much lower rate (By similarity). May import (deoxy)nucleoside triphosphates in exchange for intramitochondrial (deoxy)nucleoside mono- and diphosphates, thus providing precursors necessary for de novo synthesis of mitochondrial DNA and RNA while exporting products of their catabolism (By similarity). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (By similarity). {ECO:0000250|UniProtKB:Q96CQ1}.
uniprot
proteins
mass_dalton
34170
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
311
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q96CQ1}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..27; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 41..57; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 111..131; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 180..200; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 291..311; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins