SETDB2
entrez
83852
canonical
uniprot
Q96T68
canonical
ensembl
ENSG00000136169
resolver
ensp
ENSP00000346175
resolver
ensp
ENSP00000482240
resolver
ensp
ENSP00000635853
resolver
ensp
ENSP00000684238
resolver
ensp
ENSP00000751030
resolver
genesymbol
SETDB2
resolver
genesymbol_syn
C13orf4
resolver
genesymbol_syn
CLLD8
resolver
genesymbol_syn
KMT1F
resolver
hgnc
HGNC:20263
resolver
uniprot
Q5TC65
resolver
uniprot
Q5TC66
resolver
uniprot
Q5W0A7
resolver
uniprot
Q659A7
resolver
uniprot
Q86UD6
resolver
uniprot
Q96AI6
resolver
uniprot_entry
SETB2_HUMAN
resolver
uniprot_sec
Q5TC65
resolver
uniprot_sec
Q5TC66
resolver
uniprot_sec
Q5W0A7
resolver
uniprot_sec
Q659A7
resolver
uniprot_sec
Q86UD6
resolver
uniprot_sec
Q96AI6
resolver
amino_acid_sequence
MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEATIINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKTNSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
uniprot
proteins
ec_number
2.1.1.366
uniprot
proteins
function
FUNCTION: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. {ECO:0000269|PubMed:20404330}.
uniprot
proteins
mass_dalton
81894
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
pubmed
11306461
uniprot
proteins
pubmed
12754510
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
20404330
uniprot
proteins
sequence_length
719
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20404330}. Chromosome {ECO:0000305|PubMed:20404330}.
uniprot
proteins