Tmem150c
entrez
360916
canonical
uniprot
B5DFH9
canonical
ensembl
ENSRNOG00000002258
resolver
ensembl
ENSRNOG00055006197
resolver
ensembl
ENSRNOG00060011033
resolver
ensembl
ENSRNOG00065012761
resolver
ensp
ENSRNOP00000110270
resolver
ensp
ENSRNOP00055007784
resolver
ensp
ENSRNOP00060014534
resolver
ensp
ENSRNOP00065016030
resolver
enst
ENSRNOT00000138364
resolver
enst
ENSRNOT00055010060
resolver
enst
ENSRNOT00060018662
resolver
enst
ENSRNOT00065020824
resolver
genesymbol
Tmem150c
resolver
uniprot_entry
T150C_RAT
resolver
amino_acid_sequence
MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAARKSGVKHAPYISFAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRAGIPRVILSAVITLCVVLYFILMAQDIHMYAARVQWGLVMCFLAYFGTLAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV
uniprot
proteins
function
FUNCTION: Nonselective cationic channel with high permeability to Ca(2+). Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception. {ECO:0000250|UniProtKB:Q8C8S3}.
uniprot
proteins
mass_dalton
27815
uniprot
proteins
protein_family
DRAM/TMEM150 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
249
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:B9EJG8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:B9EJG8}. Lysosome membrane {ECO:0000250|UniProtKB:B9EJG8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:B9EJG8}. Note=Localizes at the plasma membrane. A portion co-localizes with LAMP1 lysosomal marker. {ECO:0000250|UniProtKB:B9EJG8}.
uniprot
proteins
transmembrane_region
TRANSMEM 10..30; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 65..85; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..151; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 169..189; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 193..213; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins