Chn2
entrez
69993
canonical
uniprot
Q80XD1
canonical
ensembl
ENSMUSG00000004633
resolver
ensp
ENSMUSP00000035908
resolver
ensp
ENSMUSP00000066078
resolver
ensp
ENSMUSP00000110043
resolver
ensp
ENSMUSP00000110044
resolver
ensp
ENSMUSP00000114476
resolver
enst
ENSMUST00000046856
resolver
genesymbol
Chn2
resolver
genesymbol_syn
Arhgap3
resolver
genesymbol_syn
Bch
resolver
uniprot
F7AHF6
resolver
uniprot
Q3TVA5
resolver
uniprot
Q3V2R3
resolver
uniprot
Q9D9W2
resolver
uniprot
Q9ER57
resolver
uniprot_entry
CHIO_MOUSE
resolver
uniprot_entry
F7AHF6_MOUSE
resolver
uniprot_entry
Q3TVA5_MOUSE
resolver
uniprot_entry
Q3V2R3_MOUSE
resolver
uniprot_sec
Q9D9W2
resolver
uniprot_sec
Q9ER57
resolver
activity_regulation
ACTIVITY REGULATION: In the inactive state, the N terminus protrudes into the active site of the Rho-GAP domain, sterically blocking Rac binding. Phospholipid binding to the Phorbol-ester/DAG-type zinc-finger/C1 domain triggers the cooperative dissociation of these interactions, allowing the N-terminus to move out of the active site and thereby activating the enzyme (By similarity). {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MCSQELWLENERKCAMVRKSKPSRKRQELLAIAFGVKVGLKGGFLWSPLKLFACSQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANIYPDINIITGALKLYFRDLPIPIITYDTYSKFIEAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNLMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
uniprot
proteins
function
FUNCTION: GTPase-activating protein for p21-rac. {ECO:0000250}.
uniprot
proteins
mass_dalton
38218
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
uniprot
proteins