Sidt1
entrez
320007
canonical
uniprot
Q6AXF6
canonical
ensembl
ENSMUSG00000022696
resolver
ensp
ENSMUSP00000038433
resolver
ensp
ENSMUSP00000115372
resolver
ensp
ENSMUSP00000170871
resolver
ensp
ENSMUSP00000170873
resolver
enst
ENSMUST00000047446
resolver
genesymbol
Sidt1
resolver
uniprot
E9Q247
resolver
uniprot
Q6Q3F6
resolver
uniprot
Q8BZK2
resolver
uniprot
Q8R397
resolver
uniprot_entry
E9Q247_MOUSE
resolver
uniprot_entry
Q6Q3F6_MOUSE
resolver
uniprot_entry
Q8BZK2_MOUSE
resolver
uniprot_entry
SIDT1_MOUSE
resolver
uniprot_sec
Q8R397
resolver
amino_acid_sequence
MLDCLRLALLCALPWLLRAAVPGHQEEPLAKSAELRRDPRDPARGADFDRVYSGVVSLSTENIYSFNHTSHPGQVTAVRVHVNSSSDNLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLEQLIFVDVASMAPHGAHYKLLVTKIKHFQLPTNVAFYFTASPSQPQYFLYKFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPDEQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSIFVFLSFYLGCLLVVLVHHVRFQRKSIDGSFGSSDGSGNMAVSHPITASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWIIFSAIHILSSLALSTQIYYMGRFKIDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPLPVFCIAATAVVWAAALYFFFQNLSSWEGTPAESREKNRECVLLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF
uniprot
proteins
function
FUNCTION: In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp (PubMed:26067272). Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded (PubMed:27046251). {ECO:0000269|PubMed:26067272, ECO:0000269|PubMed:27046251}.
uniprot
proteins
mass_dalton
93896
uniprot
proteins
mutagenesis
MUTAGEN 169; /note="F->T: Decreased affinity for 700-bp RNA."; /evidence="ECO:0000269|PubMed:26067272"; MUTAGEN 186; /note="P->L: Decreased affinity for 700-bp RNA."; /evidence="ECO:0000269|PubMed:26067272
uniprot
proteins
protein_family
SID1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26067272
uniprot
proteins
pubmed
27046251
uniprot
proteins
sequence_length
827
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 310..330; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 443..463; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 495..515; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 542..562; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 573..590; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 601..621; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 627..647; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 684..704; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 711..731; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 742..762; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 792..812; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins