H2az2
entrez
77605
canonical
uniprot
Q3THW5
canonical
ensembl
ENSMUSG00000041126
resolver
ensp
ENSMUSP00000091037
resolver
ensp
ENSMUSP00000105359
resolver
enst
ENSMUST00000093346
resolver
enst
ENSMUST00000109737
resolver
genesymbol
H2az2
resolver
genesymbol_syn
H2afv
resolver
genesymbol_syn
H2av
resolver
uniprot
A0ACM8Q201
resolver
uniprot
B2RVP5
resolver
uniprot
Q5NC91
resolver
uniprot
Q5NC92
resolver
uniprot
Q6ZWU0
resolver
uniprot
Q8R029
resolver
uniprot_entry
A0ACM8Q201_MOUSE
resolver
uniprot_entry
B2RVP5_MOUSE
resolver
uniprot_entry
H2AV_MOUSE
resolver
uniprot_entry
Q8R029_MOUSE
resolver
uniprot_sec
Q5NC91
resolver
uniprot_sec
Q5NC92
resolver
uniprot_sec
Q6ZWU0
resolver
amino_acid_sequence
MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA
uniprot
proteins
function
FUNCTION: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
13509
uniprot
proteins
post_translational_modification
PTM: Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression. {ECO:0000250}.; PTM: Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis. {ECO:0000269|PubMed:16204459}.
uniprot
proteins
protein_family
Histone H2A family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16204459
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
128
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
uniprot
proteins