Tyw1
entrez
100929
canonical
uniprot
Q8BJM7
canonical
ensembl
ENSMUSG00000056310
resolver
ensp
ENSMUSP00000037173
resolver
ensp
ENSMUSP00000047318
resolver
ensp
ENSMUSP00000098226
resolver
ensp
ENSMUSP00000269004
resolver
enst
ENSMUST00000044204
resolver
genesymbol
Tyw1
resolver
genesymbol_syn
Rsafd1
resolver
uniprot
A0A0R4J0L2
resolver
uniprot
Q3TRC5
resolver
uniprot
Q8BLG4
resolver
uniprot
Q8R0C7
resolver
uniprot_entry
A0A0R4J0L2_MOUSE
resolver
uniprot_entry
TYW1_MOUSE
resolver
uniprot_sec
Q3TRC5
resolver
uniprot_sec
Q8BLG4
resolver
uniprot_sec
Q8R0C7
resolver
amino_acid_sequence
MGPLDVWDLSPLLSLWMNRFYIYMGCALGLTLCICVQIIKKQVTRSQEKRVPGAPDSSLSPQKKQTHVSGVKIFYGSQTGTAKGFAVVLAKAVTSLDLPVAIINLKEYDPDDSLIGEITSKTVCAFLVATYTDGCPTESAEWFCKWLEESANDFRFGKTYLKGLRYAVFGLGDSAYRSHFNKVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHGSIEADFTAWKTKFISRLQALQRGEKKACGGNCKRGKCESAQHGPGEARPHPQGELHPGDAEEEEPCESSSEDELGTQDYQSLTSVVDVEDLGNIMNPVKREKREKSHQDGKAAMQRNPEKTEDGEGRAMITPALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHQNMIKQFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISSFLVTNAQFPEEIRKLTPVTQLYVSVDASTRDGLKKIDRPLFKDFWQRFLDSLKALSAKQQRTVYRLTLVKCWNVDELQAYAELVSLGNPDFIEVKGVTYCGESAASSLTMANVPWHEEVVRFVRELVDLLPDYEVACEHEHSNCLLIGHKKFKIDGEWWTWINYSRFQELVLQYEESGGSKTFSSRDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC
uniprot
proteins
ec_number
4.1.3.44
uniprot
proteins
function
FUNCTION: Involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis. {ECO:0000250|UniProtKB:Q08960}.
uniprot
proteins
mass_dalton
81599
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
uniprot
proteins
protein_family
TYW1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
721
uniprot
proteins