CSNK2A3
entrez
283106
canonical
uniprot
Q8NEV1
canonical
ensembl
ENSG00000254598
resolver
ensp
ENSP00000473553
resolver
enst
ENST00000528848
resolver
genesymbol
CSNK2A3
resolver
genesymbol_syn
CSNK2A1P
resolver
hgnc
HGNC:2458
resolver
uniprot_entry
CSK23_HUMAN
resolver
amino_acid_sequence
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWRLGCMLASMIFRKEPFFHGRDNYDQLVRIAKFLGTEDLYGYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANVMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAATGAQQ
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down-regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression. {ECO:0000269|PubMed:20625391}.
uniprot
proteins
mass_dalton
45220
uniprot
proteins
protein_family
CK2 subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
12102635
uniprot
proteins
pubmed
1610905
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
20625391
uniprot
proteins
pubmed
8420794
uniprot
proteins
sequence_length
391
uniprot
proteins