P25785
uniprot
P25785
canonical
amino_acid_sequence
MGAAARSLRLALGLLLLASLVRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
uniprot
proteins
function
FUNCTION: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
uniprot
proteins
mass_dalton
24328
uniprot
proteins
post_translational_modification
PTM: The activity of TIMP2 is dependent on the presence of disulfide bonds.
uniprot
proteins
protein_family
Protease inhibitor I35 (TIMP) family
uniprot
proteins
pubmed
1601312
uniprot
proteins
pubmed
1639268
uniprot
proteins
pubmed
16985004
uniprot
proteins
pubmed
1851244
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
220
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins