Nabp1
entrez
363227
canonical
uniprot
Q5FVP2
canonical
ensembl
ENSRNOG00000015416
resolver
ensembl
ENSRNOG00055004656
resolver
ensembl
ENSRNOG00060016125
resolver
ensembl
ENSRNOG00065003029
resolver
ensp
ENSRNOP00000021403
resolver
ensp
ENSRNOP00055005561
resolver
ensp
ENSRNOP00060022184
resolver
ensp
ENSRNOP00065003018
resolver
enst
ENSRNOT00000021403
resolver
enst
ENSRNOT00055007403
resolver
enst
ENSRNOT00060027618
resolver
enst
ENSRNOT00065004246
resolver
genesymbol
Nabp1
resolver
genesymbol_syn
Obfc2a
resolver
genesymbol_syn
Ssb2
resolver
uniprot_entry
SOSB2_RAT
resolver
amino_acid_sequence
MHGVNDPPLFIKDIKAGLKNLNVVFIVLEIGRVTKTKDGHEVRSCKVADRTGSITISVWDEIGGLIQTGDIIRLTRGYASMWKGCLTLYTGRGGELQKIGEFCMVYSEVPNFSEPNPDYRGQQNRVVQNEQKDKMNTSIFGTVGNGVQTGPESRGYPLQYGRSNGPGPISPQLPGEPSNQTVRTTISNARDPRRAFKR
uniprot
proteins
function
FUNCTION: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
21855
uniprot
proteins
protein_family
SOSS-B family
uniprot
proteins
protein_family
SOSS-B2 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Localizes to nuclear foci following DNA damage. {ECO:0000250}.
uniprot
proteins