Pon1
entrez
84024
canonical
uniprot
P55159
canonical
ensembl
ENSRNOG00000008902
resolver
ensp
ENSRNOP00000106355
resolver
enst
ENSRNOT00000122056
resolver
genesymbol
Pon1
resolver
genesymbol_syn
Pon
resolver
uniprot
O08682
resolver
uniprot
Q5BJN6
resolver
uniprot_entry
PON1_RAT
resolver
uniprot_sec
O08682
resolver
uniprot_sec
Q5BJN6
resolver
amino_acid_sequence
MAKLLGLTLVGLVLALYKNHRSSYQTRLNAFREVTPVDLPNCTLVKGIEAGAEDLEILPNGLTFFSTGLKYPGIKSFDPSKPGKILLMDLNEKEPAVSELAIMGNTLDMSSFNPHGISTFIDEDNTVYLLVVSHPDSSSTVEVFKFQEEERSLLHLKTITHELLPSINDIAAVGPESFYATNDHYFADPYLRSWEMYLGLSWSNVVYYSPDKVRVVADGFDFANGIGISLDGKYVYIAELLAHKIHVYEKHANWTLTPLKVLSFDTLVDNISVDPVTGDLWVGCHPNGMRIFFYDSENPPGSEVLRIQSILSEDPKVTVVYAENGTVLQGTTVAAVYKGKLLIGTVFHRALCCDL
uniprot
proteins
ec_number
3.1.1.2
uniprot
proteins
ec_number
3.1.1.81
uniprot
proteins
ec_number
3.1.8.1
uniprot
proteins
function
FUNCTION: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification. {ECO:0000250|UniProtKB:P27169}.
uniprot
proteins
mass_dalton
39358
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250|UniProtKB:P27169}.; PTM: The signal sequence is not cleaved.
uniprot
proteins
protein_family
Paraoxonase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9032442
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space.
uniprot
proteins