Pdgfa
entrez
25266
canonical
uniprot
P28576
canonical
ensembl
ENSRNOG00000001312
resolver
ensp
ENSRNOP00000040116
resolver
ensp
ENSRNOP00000101648
resolver
enst
ENSRNOT00000127993
resolver
genesymbol
Pdgfa
resolver
genesymbol_syn
Rpa1
resolver
uniprot
A0ABK0L0L7
resolver
uniprot
A6K1Y8
resolver
uniprot
Q6P7C3
resolver
uniprot_entry
A0ABK0L0L7_RAT
resolver
uniprot_entry
A6K1Y8_RAT
resolver
uniprot_entry
PDGFA_RAT
resolver
uniprot_sec
Q6P7C3
resolver
amino_acid_sequence
MRTWACLLLLGCGYLAHALAEEAEIPRELIERLARSQIHSIRDLQRLLEIDSVGAEDALETNLRAHGSHTVKHVPEKRPVPIRRKRSIEEAIPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATSNLNPDHREEETGRRRESGKKRK
uniprot
proteins
function
FUNCTION: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
23307
uniprot
proteins
protein_family
PDGF/VEGF growth factor family
uniprot
proteins
pubmed
8318539
uniprot
proteins
pubmed
8447423
uniprot
proteins
pubmed
8469035
uniprot
proteins
sequence_length
204
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted. Note=Released by platelets upon wounding. {ECO:0000250}.
uniprot
proteins