Nags
entrez
217214
canonical
uniprot
Q8R4H7
canonical
ensembl
ENSMUSG00000048217
resolver
ensp
ENSMUSP00000050258
resolver
genesymbol
Nags
resolver
uniprot
B1AQG2
resolver
uniprot
Q8C6G6
resolver
uniprot
Q8CI77
resolver
uniprot
Q8K1R8
resolver
uniprot_entry
NAGS_MOUSE
resolver
uniprot_sec
B1AQG2
resolver
uniprot_sec
Q8C6G6
resolver
uniprot_sec
Q8CI77
resolver
uniprot_sec
Q8K1R8
resolver
activity_regulation
ACTIVITY REGULATION: Increased by L-arginine. {ECO:0000269|PubMed:12049647}.
uniprot
proteins
amino_acid_sequence
MATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGAKSASPGRRLSTARAHAEDAEGAKGRVQSPAVEEPSWTPLPTPLESPAPPAGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCYHSVDKPFAVMEVDEEVIRCPQAVSRLAFALAFLQRMDMKPLVVLGLPTPTAPSGCLSFWEAKAQLAQSCKVLVDELRHNAATAVPFFGGGSVLSAAEPAPHASYGGIVAVETDLLQWCLESNSIPILCPIGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRNNSQKILSNVNLPADLDLVTNAEWLSIKERQQIRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRNLDSLDQGRLVNLVNASFGKKLREDYLESLRPRLHSIYVSEGYNAAAILTVEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFCKPASDPGS
uniprot
proteins
ec_number
2.3.1.1
uniprot
proteins
function
FUNCTION: Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity. {ECO:0000269|PubMed:12049647}.
uniprot
proteins
mass_dalton
57489
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. {ECO:0000305|PubMed:12049647}.
uniprot
proteins
post_translational_modification
PTM: Probably processed by mitochondrial processing peptidase (MPP). The long form has not yet been isolated. {ECO:0000269|PubMed:15050968}.
uniprot
proteins
protein_family
Acetyltransferase family
uniprot
proteins
pubmed
12049647
uniprot
proteins
pubmed
15050968
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23894642
uniprot
proteins
sequence_length
527
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q8N159}.
uniprot
proteins