Phaf1
entrez
207123
canonical
uniprot
O08654
canonical
ensembl
ENSRNOG00000014668
resolver
ensp
ENSRNOP00000020003
resolver
ensp
ENSRNOP00000069827
resolver
enst
ENSRNOT00000020003
resolver
enst
ENSRNOT00000085891
resolver
genesymbol
Phaf1
resolver
genesymbol_syn
RGD621098
resolver
uniprot
A0A0G2JWC6
resolver
uniprot
G3V7W8
resolver
uniprot_entry
A0A0G2JWC6_RAT
resolver
uniprot_entry
G3V7W8_RAT
resolver
uniprot_entry
PHAF1_RAT
resolver
amino_acid_sequence
MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLLFDAFNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVIRDGTGPSGLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENAGGQTEICTTYSKWDSIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP
uniprot
proteins
function
FUNCTION: Plays a regulatory role in autophagic activity. In complex with BCAS3, associates with the autophagosome formation site during both non-selective and selective autophagy. {ECO:0000250|UniProtKB:Q9BSU1}.
uniprot
proteins
mass_dalton
47463
uniprot
proteins
protein_family
PHAF1 family
uniprot
proteins
pubmed
9480860
uniprot
proteins
sequence_length
422
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BSU1}. Preautophagosomal structure {ECO:0000250|UniProtKB:Q9BSU1}. Note=The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner. {ECO:0000250|UniProtKB:Q9BSU1}.
uniprot
proteins