Hs3st5
entrez
319415
canonical
uniprot
Q8BSL4
canonical
ensembl
ENSMUSG00000044499
resolver
ensp
ENSMUSP00000060229
resolver
ensp
ENSMUSP00000129434
resolver
ensp
ENSMUSP00000130778
resolver
ensp
ENSMUSP00000295376
resolver
ensp
ENSMUSP00000295377
resolver
enst
ENSMUST00000058738
resolver
enst
ENSMUST00000167191
resolver
enst
ENSMUST00000168572
resolver
genesymbol
Hs3st5
resolver
genesymbol_syn
Hs3ost5
resolver
uniprot
B2RXW6
resolver
uniprot_entry
B2RXW6_MOUSE
resolver
uniprot_entry
HS3S5_MOUSE
resolver
amino_acid_sequence
MLFKQQVWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPVESRFGGAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVHLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP
uniprot
proteins
ec_number
2.8.2.23
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. Also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
40471
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
346
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 13..32; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins