Polr2e
entrez
66420
canonical
uniprot
Q80UW8
canonical
ensembl
ENSMUSG00000004667
resolver
ensp
ENSMUSP00000004786
resolver
enst
ENSMUST00000004786
resolver
genesymbol
Polr2e
resolver
uniprot
Q3V214
resolver
uniprot_entry
Q3V214_MOUSE
resolver
uniprot_entry
RPAB1_MOUSE
resolver
amino_acid_sequence
MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYVLEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRESQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAGRYITYRLVQ
uniprot
proteins
function
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPABC1 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:P19388, ECO:0000250|UniProtKB:P20434}.
uniprot
proteins
mass_dalton
24570
uniprot
proteins
protein_family
Archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
210
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P19388}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P19388}.
uniprot
proteins