IL17RE
entrez
132014
canonical
uniprot
Q8NFR9
canonical
ensembl
ENSG00000163701
resolver
ensp
ENSP00000373325
resolver
ensp
ENSP00000388086
resolver
ensp
ENSP00000404916
resolver
ensp
ENSP00000535494
resolver
genesymbol
IL17RE
resolver
hgnc
HGNC:18439
resolver
uniprot
B2RB34
resolver
uniprot
B2RNR1
resolver
uniprot
B4DMZ3
resolver
uniprot
B9EH65
resolver
uniprot
Q6P532
resolver
uniprot
Q8N8H7
resolver
uniprot
Q8N8H8
resolver
uniprot
Q8TEC2
resolver
uniprot_entry
B4DMZ3_HUMAN
resolver
uniprot_entry
I17RE_HUMAN
resolver
uniprot_sec
B2RB34
resolver
uniprot_sec
B2RNR1
resolver
uniprot_sec
B9EH65
resolver
uniprot_sec
Q6P532
resolver
uniprot_sec
Q8N8H7
resolver
uniprot_sec
Q8N8H8
resolver
uniprot_sec
Q8TEC2
resolver
amino_acid_sequence
MGSSRLAALLLPLLLIVIDLSDSAGIGFRHLPHWNTRCPLASHTDDSFTGSSAYIPCRTWWALFSTKPWCVRVWHCSRCLCQHLLSGGSGLQRGLFHLLVQKSKKSSTFKFYRRHKMPAPAQRKLLPRRHLSEKSHHISIPSPDISHKGLRSKRTQPSDPETWESLPRLDSQRHGGPEFSFDLLPEARAIRVTISSGPEVSVRLCHQWALECEELSSPYDVQKIVSGGHTVELPYEFLLPCLCIEASYLQEDTVRRKKCPFQSWPEAYGSDFWKSVHFTDYSQHTQMVMALTLRCPLKLEAALCQRHDWHTLCKDLPNATARESDGWYVLEKVDLHPQLCFKFSFGNSSHVECPHQTGSLTSWNVSMDTQAQQLILHFSSRMHATFSAAWSLPGLGQDTLVPPVYTVSQARGSSPVSLDLIIPFLRPGCCVLVWRSDVQFAWKHLLCPDVSYRHLGLLILALLALLTLLGVVLALTCRRPQSGPGPARPVLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWLWAARTRVAREQGTVLLLWSGADLRPVSGPDPRAAPLLALLHAAPRPLLLLAYFSRLCAKGDIPPPLRALPRYRLLRDLPRLLRALDARPFAEATSWGRLGARQRRQSRLELCSRLEREAARLADLG
uniprot
proteins
function
FUNCTION: Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors. {ECO:0000269|PubMed:21993848, ECO:0000269|PubMed:21993849}.
uniprot
proteins
mass_dalton
74810
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16310341
uniprot
proteins
pubmed
21993848
uniprot
proteins
pubmed
21993849
uniprot
proteins
sequence_length
667
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 5]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 455..475; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins