CD302
entrez
9936
canonical
uniprot
Q8IX05
canonical
ensembl
ENSG00000241399
resolver
ensp
ENSP00000259053
resolver
ensp
ENSP00000394301
resolver
ensp
ENSP00000451446
resolver
enst
ENST00000553424
resolver
genesymbol
CD302
resolver
genesymbol_syn
CLEC13A
resolver
genesymbol_syn
DCL1
resolver
genesymbol_syn
KIAA0022
resolver
hgnc
HGNC:30843
resolver
uniprot
A0A087WT00
resolver
uniprot
A8K5G4
resolver
uniprot
B4E2T9
resolver
uniprot
Q15009
resolver
uniprot_entry
A0A087WT00_HUMAN
resolver
uniprot_entry
CD302_HUMAN
resolver
uniprot_sec
A8K5G4
resolver
uniprot_sec
B4E2T9
resolver
uniprot_sec
Q15009
resolver
amino_acid_sequence
MLRAALPALLLPLLGLAAAAVADCPSSTWIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILDTLKKQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTGEWKKGNCEVSSVEGTLCKTAIPYKRKYLSDNHILISALVIASTVILTVLGAIIWFLYKKHSDSRFTTVFSTAPQSPYNEDCVLVVGEENEYPVQFD
uniprot
proteins
function
FUNCTION: Multifunctional C-type lectin receptor involved in endocytosis, phagocytosis and regulation of cell adhesion and migration (PubMed:17947679, PubMed:27316686). Plays a critical role in guiding dendritic cells to lymph nodes (PubMed:27316686). Also functions as a restriction factor for Hepatitis C virus (HCV) at the liver cell surface, likely by inhibiting a viral cell entry step (PubMed:35297672). {ECO:0000269|PubMed:17947679, ECO:0000269|PubMed:27316686, ECO:0000269|PubMed:35297672}.
uniprot
proteins
mass_dalton
26183
uniprot
proteins
post_translational_modification
PTM: May be heterogeneously N-glycosylated in some cell types. {ECO:0000269|PubMed:17947679}.
uniprot
proteins
pubmed
12824192
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17947679
uniprot
proteins
pubmed
26725057
uniprot
proteins
pubmed
27316686
uniprot
proteins
pubmed
35297672
uniprot
proteins
pubmed
7584026
uniprot
proteins
sequence_length
232
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:35297672}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, filopodium {ECO:0000269|PubMed:17947679}. Cytoplasm, cell cortex {ECO:0000269|PubMed:17947679}. Cell projection, microvillus {ECO:0000269|PubMed:17947679}. Note=Colocalizes with F-actin in filopodia, cellular cortex and microvilli of the apical cell surface.
uniprot
proteins
transmembrane_region
TRANSMEM 169..189; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins