Dync1i1
entrez
13426
canonical
uniprot
O88485
canonical
ensembl
ENSMUSG00000029757
resolver
ensp
ENSMUSP00000111216
resolver
ensp
ENSMUSP00000111217
resolver
ensp
ENSMUSP00000111218
resolver
ensp
ENSMUSP00000111221
resolver
ensp
ENSMUSP00000243285
resolver
ensp
ENSMUSP00000243312
resolver
ensp
ENSMUSP00000243322
resolver
ensp
ENSMUSP00000243333
resolver
ensp
ENSMUSP00000243335
resolver
enst
ENSMUST00000115555
resolver
enst
ENSMUST00000115556
resolver
genesymbol
Dync1i1
resolver
genesymbol_syn
Dnci1
resolver
genesymbol_syn
Dncic1
resolver
uniprot
D3Z0M6
resolver
uniprot
D6Q0F3
resolver
uniprot
D6Q0F4
resolver
uniprot
F6XK66
resolver
uniprot
O88486
resolver
uniprot
Q3TYJ3
resolver
uniprot
Q80W09
resolver
uniprot_entry
D3Z0M6_MOUSE
resolver
uniprot_entry
D6Q0F3_MOUSE
resolver
uniprot_entry
D6Q0F4_MOUSE
resolver
uniprot_entry
DC1I1_MOUSE
resolver
uniprot_entry
F6XK66_MOUSE
resolver
uniprot_entry
Q3TYJ3_MOUSE
resolver
uniprot_sec
O88486
resolver
uniprot_sec
Q80W09
resolver
amino_acid_sequence
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSDAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVEPKIGHDSELENQEKKQETKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELAA
uniprot
proteins
function
FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
uniprot
proteins
mass_dalton
70725
uniprot
proteins
mutagenesis
MUTAGEN 151..155; /note="Missing: Abolishes interaction with DYNLL2."; /evidence="ECO:0000269|PubMed:11148209"; MUTAGEN 153; /note="T->A: Impairs interaction with DYNLL2."; MUTAGEN 153; /note="T->G: Abolishes interaction with DYNLL2."; MUTAGEN 154; /note="Q->A: Abolishes interaction with DYNLL2."; MUTAGEN 155; /note="T->G: Abolishes interaction with DYNLL2."; MUTAGEN 155; /note="T->S: Impairs interaction with DYNLL2.
uniprot
proteins
protein_family
Dynein intermediate chain family
uniprot
proteins
pubmed
10049579
uniprot
proteins
pubmed
11148209
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
628
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}.
uniprot
proteins