Erp44
entrez
76299
canonical
uniprot
Q9D1Q6
canonical
ensembl
ENSMUSG00000028343
resolver
ensp
ENSMUSP00000030028
resolver
enst
ENSMUST00000030028
resolver
genesymbol
Erp44
resolver
genesymbol_syn
Kiaa0573
resolver
genesymbol_syn
Txndc4
resolver
uniprot
Q3TVI1
resolver
uniprot
Q6A045
resolver
uniprot_entry
ERP44_MOUSE
resolver
uniprot_sec
Q3TVI1
resolver
uniprot_sec
Q6A045
resolver
amino_acid_sequence
MNPAVFLSLADLRCSLLLLVTSIFTPITAEIASLDSENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEYPDKNQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSNPVHEIQSLDEVTNLDRSKRNIIGYFEQKDSENYRVFERVASILHDDCAFLSAFGDLSKPERYNGDNVIYKPPGRSAPDMVYLGSMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKDDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQDQDVASSPPESSFQKLAPSEYRYTLLRDRDEL
uniprot
proteins
function
FUNCTION: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. {ECO:0000250|UniProtKB:Q9BS26}.
uniprot
proteins
mass_dalton
46853
uniprot
proteins
mutagenesis
MUTAGEN 58; /note="C->S: No effect on interaction with ITPR1."; /evidence="ECO:0000269|PubMed:15652484
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15652484
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
406
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:15652484}.
uniprot
proteins