RNF130
entrez
55819
canonical
uniprot
Q86XS8
canonical
ensembl
ENSG00000113269
resolver
ensp
ENSP00000261947
resolver
ensp
ENSP00000429509
resolver
ensp
ENSP00000430237
resolver
enst
ENST00000522208
resolver
genesymbol
RNF130
resolver
hgnc
HGNC:18280
resolver
uniprot
E5RI87
resolver
uniprot
J3KN31
resolver
uniprot
Q2HIY3
resolver
uniprot
Q32P32
resolver
uniprot
Q59EL1
resolver
uniprot
Q641P9
resolver
uniprot
Q6P177
resolver
uniprot
Q7L2U2
resolver
uniprot
Q9P0J9
resolver
uniprot_entry
E5RI87_HUMAN
resolver
uniprot_entry
GOLI_HUMAN
resolver
uniprot_entry
Q2HIY3_HUMAN
resolver
uniprot_sec
J3KN31
resolver
uniprot_sec
Q32P32
resolver
uniprot_sec
Q59EL1
resolver
uniprot_sec
Q641P9
resolver
uniprot_sec
Q6P177
resolver
uniprot_sec
Q7L2U2
resolver
uniprot_sec
Q9P0J9
resolver
amino_acid_sequence
MSCAGRAGPARLAALALLTCSLWPARADNASQEYYTALINVTVQEPGRGAPLTFRIDRGRYGLDSPKAEVRGQVLAPLPLHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRSALGDLAGDNSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: May have a role during the programmed cell death of hematopoietic cells (By similarity). Acts as an E3 ubiquitin-protein ligase. {ECO:0000250, ECO:0000269|PubMed:16549277}.
uniprot
proteins
mass_dalton
46405
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:16549277}.
uniprot
proteins
post_translational_modification
PTM: In vivo measurements suggest this protein is glycosylated (PubMed:19159218). In contrast, in vitro experiments failed to detect glycosylation (PubMed:16549277). {ECO:0000269|PubMed:16549277, ECO:0000269|PubMed:19159218}.
uniprot
proteins
pubmed
13679316
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16549277
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
19690332
uniprot
proteins
sequence_length
419
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16549277}.
uniprot
proteins
transmembrane_region
TRANSMEM 195..217; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins