TFDP2
entrez
7029
canonical
uniprot
Q14188
canonical
ensembl
ENSG00000114126
resolver
ensp
ENSP00000417585
resolver
ensp
ENSP00000418590
resolver
ensp
ENSP00000418971
resolver
ensp
ENSP00000419036
resolver
ensp
ENSP00000420599
resolver
ensp
ENSP00000420616
resolver
ensp
ENSP00000439782
resolver
ensp
ENSP00000614605
resolver
ensp
ENSP00000666924
resolver
ensp
ENSP00000666925
resolver
ensp
ENSP00000666926
resolver
ensp
ENSP00000711646
resolver
ensp
ENSP00000711650
resolver
genesymbol
TFDP2
resolver
genesymbol_syn
DP2
resolver
hgnc
HGNC:11751
resolver
uniprot
B7Z8C8
resolver
uniprot
B7Z8L5
resolver
uniprot
D3DNG1
resolver
uniprot
E9PFC3
resolver
uniprot
F8WAI2
resolver
uniprot
Q13331
resolver
uniprot
Q14187
resolver
uniprot
Q6R754
resolver
uniprot
Q8WU88
resolver
uniprot
Q9UG28
resolver
uniprot_entry
TFDP2_HUMAN
resolver
uniprot_sec
B7Z8C8
resolver
uniprot_sec
B7Z8L5
resolver
uniprot_sec
D3DNG1
resolver
uniprot_sec
E9PFC3
resolver
uniprot_sec
F8WAI2
resolver
uniprot_sec
Q13331
resolver
uniprot_sec
Q14187
resolver
uniprot_sec
Q6R754
resolver
uniprot_sec
Q8WU88
resolver
uniprot_sec
Q9UG28
resolver
amino_acid_sequence
MTAKNVGLTSTNAEVRGFIDQNLSPTKGNISFVAFPVSNTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE
uniprot
proteins
function
FUNCTION: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000305|PubMed:20176812}.
uniprot
proteins
mass_dalton
49236
uniprot
proteins
post_translational_modification
PTM: Ser-24 is probably phosphorylated by CDK2.
uniprot
proteins
protein_family
E2F/DP family
uniprot
proteins
pubmed
10090723
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16360038
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17531812
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20176812
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
7739537
uniprot
proteins
pubmed
7784053
uniprot
proteins
pubmed
8755520
uniprot
proteins
sequence_length
446
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins