SFXN2
entrez
118980
canonical
uniprot
Q96NB2
canonical
ensembl
ENSG00000156398
resolver
ensp
ENSP00000358909
resolver
ensp
ENSP00000473325
resolver
ensp
ENSP00000564037
resolver
ensp
ENSP00000564038
resolver
ensp
ENSP00000564039
resolver
ensp
ENSP00000564040
resolver
ensp
ENSP00000564042
resolver
ensp
ENSP00000564043
resolver
ensp
ENSP00000564044
resolver
ensp
ENSP00000564045
resolver
ensp
ENSP00000564046
resolver
ensp
ENSP00000564047
resolver
ensp
ENSP00000564048
resolver
ensp
ENSP00000598927
resolver
ensp
ENSP00000598928
resolver
ensp
ENSP00000624722
resolver
ensp
ENSP00000624723
resolver
ensp
ENSP00000698529
resolver
enst
ENST00000369893
resolver
enst
ENST00000459894
resolver
enst
ENST00000893978
resolver
enst
ENST00000893979
resolver
enst
ENST00000893980
resolver
enst
ENST00000893981
resolver
enst
ENST00000893983
resolver
enst
ENST00000893984
resolver
enst
ENST00000893985
resolver
enst
ENST00000893986
resolver
enst
ENST00000893987
resolver
enst
ENST00000893988
resolver
enst
ENST00000893989
resolver
enst
ENST00000928868
resolver
enst
ENST00000928869
resolver
enst
ENST00000954663
resolver
enst
ENST00000954664
resolver
genesymbol
SFXN2
resolver
hgnc
HGNC:16086
resolver
uniprot
A0A0C4DGR6
resolver
uniprot
Q5JSM6
resolver
uniprot_entry
A0A0C4DGR6_HUMAN
resolver
uniprot_entry
SFXN2_HUMAN
resolver
uniprot_sec
Q5JSM6
resolver
amino_acid_sequence
MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVPFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEPKLQDTIKAKYGELEPYVYFNKGL
uniprot
proteins
function
FUNCTION: Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria (PubMed:30442778). Involved in mitochondrial iron homeostasis by regulating heme biosynthesis (PubMed:30570704). {ECO:0000269|PubMed:30442778, ECO:0000269|PubMed:30570704}.
uniprot
proteins
mass_dalton
36232
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
12670026
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
30442778
uniprot
proteins
pubmed
30570704
uniprot
proteins
sequence_length
322
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:30442778}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000269|PubMed:30570704}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 100..122; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 142..164; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 174..192; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 228..250; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 265..287; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins