Osbpl1a
entrez
64291
canonical
uniprot
Q91XL9
canonical
ensembl
ENSMUSG00000044252
resolver
ensp
ENSMUSP00000073957
resolver
ensp
ENSMUSP00000112681
resolver
ensp
ENSMUSP00000112895
resolver
ensp
ENSMUSP00000113268
resolver
ensp
ENSMUSP00000113357
resolver
ensp
ENSMUSP00000113735
resolver
ensp
ENSMUSP00000113841
resolver
ensp
ENSMUSP00000113914
resolver
ensp
ENSMUSP00000157017
resolver
ensp
ENSMUSP00000157020
resolver
ensp
ENSMUSP00000157209
resolver
ensp
ENSMUSP00000157342
resolver
ensp
ENSMUSP00000204638
resolver
ensp
ENSMUSP00000204643
resolver
ensp
ENSMUSP00000339328
resolver
enst
ENSMUST00000119512
resolver
enst
ENSMUST00000234118
resolver
genesymbol
Osbpl1a
resolver
genesymbol_syn
Orp1
resolver
genesymbol_syn
Orp1a
resolver
genesymbol_syn
Orp1l
resolver
uniprot
A0A3Q4EG54
resolver
uniprot
F7CSF1
resolver
uniprot
O88318
resolver
uniprot
Q3TH97
resolver
uniprot
Q3V156
resolver
uniprot
Q673L8
resolver
uniprot
Q6DFU6
resolver
uniprot_entry
A0A3Q4EG54_MOUSE
resolver
uniprot_entry
F7CSF1_MOUSE
resolver
uniprot_entry
OSBL1_MOUSE
resolver
uniprot_entry
Q3V156_MOUSE
resolver
uniprot_sec
O88318
resolver
uniprot_sec
Q3TH97
resolver
uniprot_sec
Q673L8
resolver
uniprot_sec
Q6DFU6
resolver
amino_acid_sequence
MNTEAEQQLLHHARNGNAEEVRKLLAAMARMEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVEDLLKAGAKVNMLNDMGDTPLHRAAFTGRKELVLLLLEYDADSTVVNGSGQTAKEATHDKEIRNMLEAVERTQQRKLEELLLGAAREGRTAEVSALLSRPNPPDVNCSDQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLAQGAEMKHILVGNKVVHKALKRYEGPLWKSSRFFGWKLFWVVLEHGVLSWYRKQPDAVHNSYRQGCKHLTQAVCTVKPTDSCLFSIRCFDDTVHCFRVPKNSVQQSREKWLEAIEEHSAYSTHYCSQDQVTDDEEEDVVSAMDLKESLARAQTCQQRLDREIYNFLKMIKECDVAKDMLPSFLQKADIVSEASRETCVALNDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELERSLVEGSPPVSILSEEEFYDALSGSESEGSLTCLEAVTAHSFEENEVPGSSGKHRMSEGKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLDHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQTSSSEESDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMESVIPKTDCRLRPDIRAMENGEIDLASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY
uniprot
proteins
function
FUNCTION: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol. {ECO:0000250|UniProtKB:Q9BXW6}.
uniprot
proteins
mass_dalton
107795
uniprot
proteins
protein_family
OSBP family
uniprot
proteins
pubmed
12215260
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15871461
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22623793
uniprot
proteins
sequence_length
950
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Late endosome {ECO:0000250|UniProtKB:Q9BXW6}. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes. {ECO:0000250|UniProtKB:Q9BXW6}.
uniprot
proteins