Capn6
entrez
12338
canonical
uniprot
O35646
canonical
ensembl
ENSMUSG00000067276
resolver
ensp
ENSMUSP00000084573
resolver
enst
ENSMUST00000087316
resolver
genesymbol
Capn6
resolver
genesymbol_syn
Capa6
resolver
uniprot
Q3UM55
resolver
uniprot
Q80VZ1
resolver
uniprot_entry
CAN6_MOUSE
resolver
uniprot_entry
Q80VZ1_MOUSE
resolver
uniprot_sec
Q3UM55
resolver
amino_acid_sequence
MGPPLKLFKNQKYQELKQECMKDGRLFCDPTFLPENDSLFFNRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKDQEWDPRKPEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLICCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGERLVEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDIPIIIQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTEL
uniprot
proteins
function
FUNCTION: Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues. {ECO:0000269|PubMed:17210638, ECO:0000269|PubMed:21406564}.
uniprot
proteins
mass_dalton
74543
uniprot
proteins
protein_family
Peptidase C2 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17210638
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20814968
uniprot
proteins
pubmed
21406564
uniprot
proteins
pubmed
9503024
uniprot
proteins
sequence_length
641
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17210638, ECO:0000269|PubMed:20814968}.
uniprot
proteins