Qser1
entrez
99003
canonical
uniprot
A0A338P6K9
canonical
ensembl
ENSMUSG00000074994
resolver
ensp
ENSMUSP00000155882
resolver
ensp
ENSMUSP00000302362
resolver
ensp
ENSMUSP00000302366
resolver
genesymbol
Qser1
resolver
uniprot
A2BIE1
resolver
uniprot
Q3UR75
resolver
uniprot_entry
QSER1_MOUSE
resolver
uniprot_sec
A2BIE1
resolver
uniprot_sec
Q3UR75
resolver
amino_acid_sequence
MDAHYAPAGFAEPPAPPASAATQPAAPAWAYEARVPAAASSPSCSGSSPSLKASYEDGHPSQSESDVLQRQTFTASHQLPGYATTPQATGMHSSAATELFVAGPLPTTGTLPPPTLSAYQHSSTFSNRNFATTSPLVLQDSSFNTTSNGILSPHDPLLQIKTSQGTVPTALAFERLGSSALSNSVPPQSSTYRSAQESAPHLLQPQFSLLPSTLGGAQQTPQAYNSALFPSSAASIERALLRECSVIKHHQRPSVTQSIQAQLTGSQHPLHSYLSSASIGNFQEPSRQSSLSCSSVRDSTQVSNGVLPQKTPQVSAELAQSYSSVIPSSGYLPSATKVDSCSTKQPLTSTTIPKPQSVIPPVQTLNYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGLVQPHNVPSIVHSQVYRSSRVEKLPSLYKTLTFSGSSQPVTSENQTLSYSSNQQEVLSLVTNENYPAQTRDLPSVSESQNYSSGQSQGLSPVSQTQVSYSSQSQVLSVVSPSESYASGQSLTLTAPSLSYSSASRGQSLPVSTPTPSYTSMHPSPNAQTQGSSAQPQEFLPAVQSSFASSTRGQTLQSSIPSPDPKSYAERKLDSSVYTSSKQDEFPVQKLQALQSQASLESSSQRLPDGEVNAQESVYKTSKADDRYSQSVTRNNSHLEDQVVGVALQGSEQEENMVGSMTQLNQQSGQSNNAVATDLKKATNLMQTPQVRLNTKDLNQQHSLMHKMHEAKVQQQHDQIMSASSQIQIPNPALGQSHQALPHTSVLLDSACDLQILQQAGILQASLGQAKASLQVQRVQSPQQIVHPFLQMDGHIIQSNGEHPQQQLHPHNSDIMKLDLPEPSKPLQQLTTKGPFSEANPHDSKNQFVSLGSICFSEAMLLSDERNILSNVDDILAATAAACGVTPSDFSKSAANETMQDIESSDSKSHYQQSLNVRHVNSDFNSIAASVGKPQSINDISLNGNQVSVSLSSVPTLQSETVLDQPHMETPSQTIPTKVPSAMVGLGQEIQEQSSDPFKKQLTINHESKEDREIAVDSALSNNRNQEFVSNSRSISGDSVVSERDFTLVGDDTGVLVNPRRSTLALLAMPQPGDAASGKTEDEKQDVTYFNLPKEKAKGKEQGKEEEDNQKQLKRSAQCKRQNPRGTDVYVPYTSPSLESCDEGFQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKCGPKQQFSTLAVRVPNRTRRSGIQTTRTFCPPPFAKTSPAAQAPSETGGVSLSEKVDSELKTLEQLSSFSSDEEDPGSCGHDIYKNTSAPLTVLDATSDKTKKTVLEALPVATPGASAETAGVAPTASTAVATIKQDLHLTSLTVNTMENANSTESPTAIELDSLPSDQLAKGQDTVAIEGFTDEENIESGGEGQYRERDEFVVKIEDIETFKEALNTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKTKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTIRNIPSKPSSISKTSDPPVSKTTTTKTPSTKPKAKQLKIKAEPPPKKRKKWKEEFSSSQSESSPEVRSSSSEDEGFEPPAPSVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLVNLHLDQPFKNALESFPELTVITRDSKAKSGGSAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKNEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCS
uniprot
proteins
function
FUNCTION: Plays an essential role in the protection and maintenance of transcriptional and developmental programs. Protects many bivalent promoters and poised enhancers from hypermethylation, showing a marked preference for these regulatory elements over other types of promoters or enhancers. Mechanistically, cooperates with TET1 and binds to DNA in a common complex to inhibit the binding of DNMT3A/3B and therefore de novo methylation. {ECO:0000250|UniProtKB:Q2KHR3}.
uniprot
proteins
mass_dalton
194475
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
1788
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Chromosome {ECO:0000250|UniProtKB:Q2KHR3}.
uniprot
proteins