Tctn2
entrez
67978
canonical
uniprot
Q2MV57
canonical
ensembl
ENSMUSG00000118662
resolver
ensp
ENSMUSP00000159383
resolver
genesymbol
Tctn2
resolver
genesymbol_syn
Tect2
resolver
uniprot
Q6PDZ5
resolver
uniprot
Q8C0B3
resolver
uniprot
Q9CXF5
resolver
uniprot_entry
TECT2_MOUSE
resolver
uniprot_sec
Q6PDZ5
resolver
uniprot_sec
Q8C0B3
resolver
uniprot_sec
Q9CXF5
resolver
amino_acid_sequence
MGSLSPLSLLWGLLLLQGVLRPLRGDPVFIPPFIRMSSPEVRATLVGGSEDVAVSLSLLQVEEGVLPVPTCGGRRNETVDWNVTVSPRESTLEVTIRWKRGLDWCSADETASFSEPPCVLQMLLVSASHNASCLAHLLIQVEIYPNTSVTHNASENMTVIPNQVYQPLGPCPCDLTAKACDIQCCCDQDCQPEVRELFAQSCFSGVFGGHVSPPSHHHCAVSTTHQTPDWFPLLCVQSPPSTSPFLGHFYHGATSPRHSPGFEAHLHFDLRDFADASYKQGDPIMTTEGYFTIPQVSLAGQCLQDAPVAFLRNFDSVCTMDLEVHQGRDEIVLENMKIRTTGGPVTPTVTYEEAIDLDKFITSPDTVLSVGSAPRNVNVEEHYVFRWQNNSISGLDITVIRAEISAQQRGMMTQRFTVKFLSHHSGGEKEFSGNPGYQLGKPVRALHTAGMNVSTLHLWQPAGRGLCTAAALRPILFGENAFSGCLLEVGIKENCTQLRENVLQRLDLLTQATHVARRGNSDYSDLSDGWLEIIRAEAPDTGADLPLSSVNGVCPEVPARLSIRILTAEAGSVEGVAQREILAVETRFSTVTWQYQCGLTCEDKADLLPLSASVEFINVPAQMPHPPTRFQINFTEYDCTRNELCWPQLLYPLTQYYQGEPQSQCVAKGLMLLSLLMLAILLRHPWVRMCKARDSAAIYH
uniprot
proteins
function
FUNCTION: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction. {ECO:0000269|PubMed:21565611, ECO:0000269|PubMed:21725307, ECO:0000269|PubMed:22179047}.
uniprot
proteins
mass_dalton
77111
uniprot
proteins
protein_family
Tectonic family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16357211
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
21462283
uniprot
proteins
pubmed
21565611
uniprot
proteins
pubmed
21725307
uniprot
proteins
pubmed
22179047
uniprot
proteins
sequence_length
700
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:21725307}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
uniprot
proteins
transmembrane_region
TRANSMEM 666..682; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins