TF
entrez
7018
canonical
uniprot
P02787
canonical
ensembl
ENSG00000091513
resolver
ensp
ENSP00000385834
resolver
ensp
ENSP00000657267
resolver
enst
ENST00000402696
resolver
genesymbol
TF
resolver
hgnc
HGNC:11740
resolver
uniprot
A0PJA6
resolver
uniprot
O43890
resolver
uniprot
Q06AH7
resolver
uniprot
Q1HBA5
resolver
uniprot
Q9NQB8
resolver
uniprot
Q9UHV0
resolver
uniprot_entry
A0PJA6_HUMAN
resolver
uniprot_entry
Q06AH7_HUMAN
resolver
uniprot_entry
TRFE_HUMAN
resolver
uniprot_sec
O43890
resolver
uniprot_sec
Q1HBA5
resolver
uniprot_sec
Q9NQB8
resolver
uniprot_sec
Q9UHV0
resolver
amino_acid_sequence
MRLAVGALLVCAVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP
uniprot
proteins
disease_involvement
DISEASE: Atransferrinemia (ATRAF) [MIM:209300]: A rare autosomal recessive disorder characterized by abnormal synthesis of transferrin leading to iron overload and microcytic hypochromic anemia. {ECO:0000269|PubMed:11110675, ECO:0000269|PubMed:15466165}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.; FUNCTION: (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use. {ECO:0000269|PubMed:22327295, ECO:0000269|PubMed:22343719}.; FUNCTION: (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use. {ECO:0000269|PubMed:31636418}.
uniprot
proteins
mass_dalton
77064
uniprot
proteins
protein_family
Transferrin family
uniprot
proteins
pubmed
10029548
uniprot
proteins
pubmed
10931525
uniprot
proteins
pubmed
11110675
uniprot
proteins
pubmed
11702220
uniprot
proteins
pubmed
11703331
uniprot
proteins
pubmed
14760718
uniprot
proteins
pubmed
15084671
uniprot
proteins
pubmed
15466165
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15536627
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
16740002
uniprot
proteins
pubmed
1809186
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
1932003
uniprot
proteins
pubmed
19838169
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22327295
uniprot
proteins
pubmed
22343719
uniprot
proteins
pubmed
22905912
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
26091039
uniprot
proteins
pubmed
2780570
uniprot
proteins
pubmed
29950717
uniprot
proteins
pubmed
3106157
uniprot
proteins
pubmed
31636418
uniprot
proteins
pubmed
3678832
uniprot
proteins
pubmed
37277838
uniprot
proteins
pubmed
3786138
uniprot
proteins
pubmed
3858812
uniprot
proteins
pubmed
6322780
uniprot
proteins
pubmed
6585826
uniprot
proteins
pubmed
6833213
uniprot
proteins
pubmed
6953407
uniprot
proteins
pubmed
7498159
uniprot
proteins
pubmed
9272172
uniprot
proteins
pubmed
9358047
uniprot
proteins
pubmed
9609685
uniprot
proteins
pubmed
9760232
uniprot
proteins
pubmed
9803271
uniprot
proteins
sequence_length
698
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins