Dnaaf2
entrez
362746
canonical
uniprot
Q5FVL7
canonical
ensembl
ENSRNOG00000028155
resolver
ensp
ENSRNOP00000055960
resolver
enst
ENSRNOT00000059187
resolver
genesymbol
Dnaaf2
resolver
genesymbol_syn
Ktu
resolver
uniprot_entry
KTU_RAT
resolver
amino_acid_sequence
MAKTAASSALEDLDLSGEEVQRLTSAFQDPEFRRMFSDYAAEITDPENRRRYEEEITALERERGVEVRFVHPEPGHVLRTSLDGEHRCFVNVCSNSLVGAPSSRPGPGRGGTAAGSHWSLPYSLAPGRQYAGRNGNRYTVYDVVFHPEALALARSHERFREMLDATALEAVEQQFGVRLDRRNAKTLKIKYKGTPEAAVLRTPLPEGVRAQPEGELPGLLPYPPYPYHYPAAAESTARSPASPAPKAVQRPEPTEPRCSVVQRHHVDLQDYRCSRDAAPSTVPHELVVTIELPLLRSAERAELEVKGKLLCLDSRNPDYRLRLSLPYPVDDGRGRAQYNKARRQLVVTLPVALAVARQDFSTTPEGPTAETGTDNIACTSAGDLAGAREESADSSGADHGRKSCVVAPDAGTAKAEGELVPEPEQDFGGDSVTPLGPGEGTTPENRSLLYSAFQSGDAESLAERSGVYGDLSVQTSEEQEGTCHDTSGSDMGGPGTESIKPLCPPLQCNQDEDSLTLLIQVPGIQPQSLHGDLSPFSYELCFSTQDSGYSFTLQFAPENKLSTKEPAISISLNNAVIVLAKSPESHGLWREWYWGLNKDSLEERLFIDEENVNEFLEEVVRSPLKPARSLSPPLIEVLQVTEEQIQIHAKLQECSDPDGLQGKEKGVKEECPLSEKENTEHSTTSTADSNSSVAVEGLKINTCGAVGLQQGCPDVPHVLSGKRLQSEAKMDPEFIRESSTAYSAEEKENIKEPVITKEKKIGGDHLSSLPNKTAVQNTHDFDTIKETNMQDGSVQIIKDHTTHCAFDFQNSLLYDLD
uniprot
proteins
function
FUNCTION: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. {ECO:0000255|HAMAP-Rule:MF_03069}.
uniprot
proteins
mass_dalton
89349
uniprot
proteins
protein_family
Kintoun subfamily
uniprot
proteins
protein_family
PIH1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
817
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03069}. Dynein axonemal particle {ECO:0000250|UniProtKB:B1H1W9}. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive pericentriolar region, not in the cilia. {ECO:0000255|HAMAP-Rule:MF_03069}.
uniprot
proteins