FMNL3
entrez
91010
canonical
uniprot
Q8IVF7
canonical
ensembl
ENSG00000161791
resolver
ensp
ENSP00000335655
resolver
ensp
ENSP00000344311
resolver
ensp
ENSP00000676314
resolver
ensp
ENSP00000676315
resolver
ensp
ENSP00000694412
resolver
ensp
ENSP00000694413
resolver
genesymbol
FMNL3
resolver
genesymbol_syn
FHOD3
resolver
genesymbol_syn
FRL2
resolver
genesymbol_syn
KIAA2014
resolver
genesymbol_syn
WBP3
resolver
hgnc
HGNC:23698
resolver
uniprot
B0JZA7
resolver
uniprot
Q6ZRJ1
resolver
uniprot_entry
FMNL3_HUMAN
resolver
uniprot_sec
B0JZA7
resolver
uniprot_sec
Q6ZRJ1
resolver
amino_acid_sequence
MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHHDESNC
uniprot
proteins
function
FUNCTION: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis (By similarity). In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignment. {ECO:0000250|UniProtKB:Q6NXC0, ECO:0000269|PubMed:21834987, ECO:0000269|PubMed:22275430}.
uniprot
proteins
mass_dalton
117213
uniprot
proteins
protein_family
Formin homology family
uniprot
proteins
pubmed
12684686
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20213681
uniprot
proteins
pubmed
21148482
uniprot
proteins
pubmed
21834987
uniprot
proteins
pubmed
22275430
uniprot
proteins
pubmed
39390519
uniprot
proteins
sequence_length
1028
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21834987}. Cell membrane {ECO:0000269|PubMed:22275430}; Lipid-anchor {ECO:0000255}. Note=Enriched in lamellipodia.
uniprot
proteins