Gulo
entrez
60671
canonical
uniprot
P10867
canonical
ensembl
ENSRNOG00000016648
resolver
ensp
ENSRNOP00000022703
resolver
enst
ENSRNOT00000022702
resolver
genesymbol
Gulo
resolver
uniprot
A0A140TAC7
resolver
uniprot
Q5EBC1
resolver
uniprot
Q64597
resolver
uniprot
Q9QWR6
resolver
uniprot_entry
A0A140TAC7_RAT
resolver
uniprot_entry
GGLO_RAT
resolver
uniprot_sec
Q5EBC1
resolver
uniprot_sec
Q64597
resolver
uniprot_sec
Q9QWR6
resolver
amino_acid_sequence
MVHGYKGVQFQNWAKTYGCSPEVYYQPTSVEEVREVLALAREQKKKVKVVGGGHSPSDIACTDGFMIHMGKMNRVLQVDKEKKQITVEAGILLADLHPQLDEHGLAMSNLGAVSDVTVAGVIGSGTHNTGIKHGILATQVVALTLMTADGEVLECSESRNADVFQAARVHLGCLGIILTVTLQCVPQFHLQETSFPSTLKEVLDNLDSHLKRSEYFRFLWFPHTENVSIIYQDHTNKAPSSASNWFWDYAIGFYLLEFLLWTSTYLPCLVGWINRFFFWMLFNCKKESSNLSHKIFTYECRFKQHVQDWAIPREKTKEALLELKAMLEAHPKVVAHYPVEVRFTRGDDILLSPCFQRDSCYMNIIMYRPYGKDVPRLDYWLAYETIMKKFGGRPHWAKAHNCTQKDFEEMYPTFHKFCDIREKLDPTGMFLNSYLEKVFY
uniprot
proteins
ec_number
1.1.3.8
uniprot
proteins
function
FUNCTION: Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate. {ECO:0000269|PubMed:8459881}.
uniprot
proteins
mass_dalton
50615
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; L-ascorbate biosynthesis via UDP-alpha-D-glucuronate pathway; L-ascorbate from UDP-alpha-D-glucuronate: step 4/4.
uniprot
proteins
protein_family
Oxygen-dependent FAD-linked oxidoreductase family
uniprot
proteins
pubmed
1400507
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1962571
uniprot
proteins
pubmed
3214183
uniprot
proteins
pubmed
3338984
uniprot
proteins
pubmed
8459881
uniprot
proteins
sequence_length
440
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 251..273; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins