CDK20
entrez
23552
canonical
uniprot
Q8IZL9
canonical
ensembl
ENSG00000156345
resolver
ensp
ENSP00000322343
resolver
ensp
ENSP00000338975
resolver
ensp
ENSP00000365031
resolver
ensp
ENSP00000365043
resolver
ensp
ENSP00000474485
resolver
ensp
ENSP00000540646
resolver
ensp
ENSP00000540647
resolver
ensp
ENSP00000596698
resolver
ensp
ENSP00000690735
resolver
ensp
ENSP00000690737
resolver
ensp
ENSP00000690739
resolver
ensp
ENSP00000690743
resolver
ensp
ENSP00000733939
resolver
genesymbol
CDK20
resolver
genesymbol_syn
CCRK
resolver
genesymbol_syn
CDCH
resolver
hgnc
HGNC:21420
resolver
uniprot
A0A0S2Z562
resolver
uniprot
A0A0S2Z5B6
resolver
uniprot
A2A389
resolver
uniprot
A2A390
resolver
uniprot
B4DQX1
resolver
uniprot
O95137
resolver
uniprot
Q5EDC4
resolver
uniprot
Q5VYW1
resolver
uniprot
Q9BUF4
resolver
uniprot_entry
A0A0S2Z562_HUMAN
resolver
uniprot_entry
A0A0S2Z5B6_HUMAN
resolver
uniprot_entry
CDK20_HUMAN
resolver
uniprot_sec
A2A389
resolver
uniprot_sec
A2A390
resolver
uniprot_sec
B4DQX1
resolver
uniprot_sec
O95137
resolver
uniprot_sec
Q5EDC4
resolver
uniprot_sec
Q5VYW1
resolver
uniprot_sec
Q9BUF4
resolver
amino_acid_sequence
MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
uniprot
proteins
ec_number
2.7.11.22
uniprot
proteins
function
FUNCTION: Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'. {ECO:0000250, ECO:0000269|PubMed:14597612}.
uniprot
proteins
mass_dalton
38695
uniprot
proteins
mutagenesis
MUTAGEN 161; /note="T->A: Impairs CDK2 T-160 phosphorylation and activity."; /evidence="ECO:0000269|PubMed:14597612
uniprot
proteins
protein_family
CDC2/CDKX subfamily
uniprot
proteins
protein_family
CMGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
14597612
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
21986944
uniprot
proteins
sequence_length
346
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14597612}. Cytoplasm {ECO:0000250}. Cell projection, cilium {ECO:0000250}.
uniprot
proteins