Ppme1
entrez
361613
canonical
uniprot
Q4FZT2
canonical
ensembl
ENSRNOG00000017227
resolver
ensembl
ENSRNOG00055027628
resolver
ensembl
ENSRNOG00060002870
resolver
ensembl
ENSRNOG00065024147
resolver
ensp
ENSRNOP00000023649
resolver
ensp
ENSRNOP00055039403
resolver
ensp
ENSRNOP00060003312
resolver
ensp
ENSRNOP00065033823
resolver
enst
ENSRNOT00055047862
resolver
enst
ENSRNOT00060004641
resolver
enst
ENSRNOT00065041405
resolver
genesymbol
Ppme1
resolver
genesymbol_syn
Pme1
resolver
uniprot_entry
PPME1_RAT
resolver
amino_acid_sequence
MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFTPVPWSQYFESMEDVEVENETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVKNSEDLSAETMAKDVGNVVEAMYGDLPPPVMLIGHSMGGAIAVHTAAANLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPESSKSIVEGIIEEEEEDEEGSESVNKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC
uniprot
proteins
ec_number
3.1.1.89
uniprot
proteins
function
FUNCTION: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme (By similarity). {ECO:0000250, ECO:0000269|PubMed:17939993}.
uniprot
proteins
mass_dalton
42316
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SIK1 following increases in intracellular sodium, leading to dissociation from the protein phosphatase 2A (PP2A) complex and subsequent dephosphorylation of sodium/potassium-transporting ATPase ATP1A1. {ECO:0000269|PubMed:17939993}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17939993
uniprot
proteins
sequence_length
386
uniprot
proteins