Fyb2
entrez
242594
canonical
uniprot
A2A995
canonical
ensembl
ENSMUSG00000078612
resolver
ensp
ENSMUSP00000102415
resolver
ensp
ENSMUSP00000102416
resolver
enst
ENSMUST00000106803
resolver
enst
ENSMUST00000106804
resolver
genesymbol
Fyb2
resolver
genesymbol_syn
1700024P16Rik
resolver
genesymbol_syn
ARAP
resolver
uniprot
E9PZ08
resolver
uniprot_entry
E9PZ08_MOUSE
resolver
uniprot_entry
FYB2_MOUSE
resolver
amino_acid_sequence
MEEEGIRNFKELRAKFQKFNAAPLPGPMRFPAGVSRKHDRGSTQPAQDLANRKCLSSHHHQTPSHSSTGVSQPLKNQTLKSAQGDELQKTSSSSGTPEKSTVCPERDFQKAAVPLDVTKSRAKTSNEEKGMTLSSFRYKLWNWEKVSSQNGEMSPAPLLTNGGIKTFHFEGQKTMGLAQDKPEKSLKATGAQTLPPQSHSMAQRKSPVTSKASSVSLPPHSRKSTKSPATEGSHRSSQCQPVYECELDSLVPEKPQSRHCRLPKTKPLPSIETLGPPPPKPSKPPFVNLYAFHRLPATVTKTPKEETMKEGPLSPDSAELEEAHNYDTTISYLRHSGNSINLCAEGESTEATYEIEIEELQKPWRSFFLPELSPRPKEEENTMEEKESWESEPLEPRKELHPSRPPKVVVYKETPGKTQMAGVHEDRRSVPAGNQEAMTDIMQNRLFPEDVTLTRHSQDKSGYVEALEVTKETPSPSTIRSSSSSEKTYDAVECSREDVRKWDFSSSFTSDSEENCEEMYEDIYKAKNDDPKTEVAGRTALRKLQQIFRKENVVFRMKKTKSKEIVSNGFSVSLPDLGPRSQDDSQDGIIYDDVDTREKESNDEDKVKTWKTKFLIPKGKKWGKGSQGSKSFSPRHFFRTKKQKLEKNRMEKEEKLFRERFQYGKEILVINRAVACASNSRNGMFDLPIIPGEQLEVIDTTEQNLVICRNSKGKYGYVLVEHLDFKHQG
uniprot
proteins
function
FUNCTION: Adapter protein that plays a role in T-cell receptor (TCR)-mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation. {ECO:0000250|UniProtKB:Q5VWT5}.
uniprot
proteins
mass_dalton
82296
uniprot
proteins
post_translational_modification
PTM: Phosphorylation is required for its function in T-cell activation. {ECO:0000250|UniProtKB:Q5VWT5}.
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
729
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane raft {ECO:0000250|UniProtKB:Q5VWT5}. Note=Recruited to membrane rafts and immunological synapse after TCR stimulation. {ECO:0000250|UniProtKB:Q5VWT5}.
uniprot
proteins