Q62270
uniprot
Q62270
canonical
amino_acid_sequence
MEPFLRKRLTFLSFFWDKIWPADESEEDIPRIQGHDDNPVPEQAAAVEPCSFPAPRARLFRALYDFTARCAEELSVSRGDRLYALKEEGDYIFAQRLSGPPSTGLVPVTYLAKATPEPPSDQPWYFSGISRAQAQQLLLSPANAPGAFLIRPSESSIGGYSLSVRAQAKVCHYRICMAPSGSLYLQEGQLFPSLDALLAYYKTNWKLIQNPLLQPCIPQIPLVQDEWERPRSEFVLRRKLGEGFFGEVWEGLWLGSIPVAVKVIKSADMKLADLTKEIEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLVGDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFAILREKLNAINRRLHLGLT
uniprot
proteins
ec_number
2.7.10.2
uniprot
proteins
function
FUNCTION: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation of KHDRBS1 is EGF-dependent. Phosphorylates OTUB1, promoting deubiquitination of RPTOR. {ECO:0000250|UniProtKB:Q9H3Y6}.
uniprot
proteins
mass_dalton
55758
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
SRC subfamily
uniprot
proteins
protein_family
Tyr protein kinase family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
7935409
uniprot
proteins
pubmed
9226137
uniprot
proteins
sequence_length
496
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H3Y6}. Note=Localizes to punctate cytoplasmic structures. {ECO:0000250|UniProtKB:Q9H3Y6}.
uniprot
proteins