CNTD
entrez
124817
canonical
uniprot
Q8N815
canonical
ensembl
ENSG00000176563
resolver
ensp
ENSP00000465204
resolver
ensp
ENSP00000468725
resolver
enst
ENST00000588527
resolver
genesymbol
CNTD
resolver
genesymbol
CNTD1
resolver
genesymbol_syn
CNTD
resolver
hgnc
HGNC:26847
resolver
uniprot
B4DXR6
resolver
uniprot
K7ESI2
resolver
uniprot
Q658Q6
resolver
uniprot
Q8NEP1
resolver
uniprot_entry
B4DXR6_HUMAN
resolver
uniprot_entry
CNTD1_HUMAN
resolver
uniprot_entry
K7ESI2_HUMAN
resolver
uniprot_sec
Q658Q6
resolver
uniprot_sec
Q8NEP1
resolver
amino_acid_sequence
MDGPMRPRSASLVDFQFGVVATETIEDALLHLAQQNEQAVREASGRLGRFREPQIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRDNKRESQNWRALKQQLVNKFTLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRINLPTPLAYVETLLEVLGYNGCLVPAMRLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQLQGEKFTSVKEDFMLLAVGIIAASAFIQNHECWSQVVGHLQSITGIALASIAEFSYAILTHGVGANTPGRQQSIPPHLAARALKTVASSNT
uniprot
proteins
function
FUNCTION: Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and simultaneously regulates cell-cycle progression through interactions with CDC34 and subsequent ubiquitination of WEE1. May also participates in an active deselection process that destabilizes or removes excess pre-CO intermediates. {ECO:0000250|UniProtKB:Q9D995}.
uniprot
proteins
mass_dalton
36921
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
330
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9D995}. Cytoplasm {ECO:0000250|UniProtKB:Q9D995}. Chromosome {ECO:0000250|UniProtKB:Q9D995}. Note=Shuttles between the nucleus and cytoplasm in a stage-specific manner of prophase I cells. Co-localized at crossover sites with PRR19. {ECO:0000250|UniProtKB:Q9D995}.
uniprot
proteins