Tomm70
entrez
304017
canonical
uniprot
Q75Q39
canonical
ensembl
ENSRNOG00000001640
resolver
ensembl
ENSRNOG00055013364
resolver
ensembl
ENSRNOG00060012523
resolver
ensembl
ENSRNOG00065002088
resolver
ensp
ENSRNOP00000002238
resolver
ensp
ENSRNOP00055018575
resolver
ensp
ENSRNOP00060016729
resolver
ensp
ENSRNOP00065001883
resolver
enst
ENSRNOT00000002238
resolver
enst
ENSRNOT00055022912
resolver
enst
ENSRNOT00060021215
resolver
enst
ENSRNOT00065002743
resolver
genesymbol
Tomm70
resolver
genesymbol_syn
Tomm70a
resolver
uniprot_entry
TOM70_RAT
resolver
amino_acid_sequence
MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGPDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL
uniprot
proteins
function
FUNCTION: Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed:11956321, PubMed:19401463). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (By similarity). {ECO:0000250|UniProtKB:O94826, ECO:0000269|PubMed:11956321, ECO:0000269|PubMed:19401463}.
uniprot
proteins
mass_dalton
67445
uniprot
proteins
protein_family
Tom70 family
uniprot
proteins
pubmed
11956321
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16396499
uniprot
proteins
pubmed
19401463
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
610
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000269|PubMed:11956321}; Single-pass membrane protein {ECO:0000269|PubMed:11956321}.
uniprot
proteins
transmembrane_region
TRANSMEM 42..62; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins