LYZ
entrez
4069
canonical
uniprot
P61626
canonical
ensembl
ENSG00000090382
resolver
ensp
ENSP00000261267
resolver
enst
ENST00000261267
resolver
genesymbol
LYZ
resolver
genesymbol_syn
LZM
resolver
hgnc
HGNC:6740
resolver
uniprot
B2R4C5
resolver
uniprot
P00695
resolver
uniprot
Q13170
resolver
uniprot
Q9UCF8
resolver
uniprot_entry
B2R4C5_HUMAN
resolver
uniprot_entry
LYSC_HUMAN
resolver
uniprot_sec
P00695
resolver
uniprot_sec
Q13170
resolver
uniprot_sec
Q9UCF8
resolver
amino_acid_sequence
MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
uniprot
proteins
disease_involvement
DISEASE: Amyloidosis, hereditary systemic 5 (AMYLD5) [MIM:620658]: A form of hereditary systemic amyloidosis, a disorder characterized by amyloid deposition in multiple tissues resulting in a wide clinical spectrum. AMYLD5 primarily affects the viscera, and the predominant clinical features are renal dysfunction of varying severity, and intra-abdominal bleeding. Inheritance is autosomal dominant. {ECO:0000269|PubMed:8464497}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
3.2.1.17
uniprot
proteins
function
FUNCTION: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
uniprot
proteins
mass_dalton
16537
uniprot
proteins
protein_family
Glycosyl hydrolase 22 family
uniprot
proteins
pubmed
11946553
uniprot
proteins
pubmed
11946554
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1794972
uniprot
proteins
pubmed
2061330
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
2207098
uniprot
proteins
pubmed
2546758
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
25946035
uniprot
proteins
pubmed
2829884
uniprot
proteins
pubmed
2971592
uniprot
proteins
pubmed
3413092
uniprot
proteins
pubmed
5168859
uniprot
proteins
pubmed
5284421
uniprot
proteins
pubmed
6876162
uniprot
proteins
pubmed
7334520
uniprot
proteins
pubmed
8464497
uniprot
proteins
pubmed
8503881
uniprot
proteins
pubmed
9757091
uniprot
proteins
sequence_length
148
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins