Q2LKV2
uniprot
Q2LKV2
canonical
amino_acid_sequence
MEESPPKQKSNTKVAQHEGQQDLNTTRHMNVELKHRPKLERHLKLGMIPVVYMKQREEILYPAQSLKEENLIQNFTSLPLLQKLCPKDPENMVRKSWASCIPEEGGHMINIQDLFGPNIGTQKEPQLVIIEGAAGIGKSTLARLVKRAWKEGQLYRDHFQHVFFFSCRELAQCKKLSLAELIAQGQEVPTAPINQILSHPEKLLFILDGIDEPAWVLADQNPELCLHWSQRQPVHTLLGSLLGKSILPEAFFLLTTRTTALQKFIPSLPMPCQVEVLGFSGIEWENYFYKYFANQRHAITAFMMVESNPVLLTLCEVPWVCWLVCTCLKKQMKQGRVLSLKSQTTTALCLKYLSLTIPDKHRRTQVKALCSLAAEGIWKRRTLFSESDLCKQGLDEDAVATFLKTGVLQKQASSLSYSFAHLCLQEFFAAISCILEDSEERHGNMEMDRIVETLVERYGRQNLFEAPTVRFLFGLLGKEGVKGMEKLFSCSLPGKTKLKLLWHILGKSQPHQPPCLGLLHCLYENQDMELLTHVMHDLQGTIVPGPNDIAHTVLQTNVKQLVVQTDMELMVATFCIQFYCHVRTLQLNMEKQQGYALTSPRMVLYRWTPITNASWEILFYNLKFTRNLEGLDLSGNSLRYSVVQSLCNTLRYPGCQLKTLWLVKCGLTSRYCSLLASVLSAHSSLTELYLQLNDLGDDGVRMLCEGLRNPVCNLSILWLDLSSLSAQVITELRTLEEKNPKLYIRSIWMPHMMVPTENMDEEAILTTFKQQRQESGDKPMEILGTEEDFWGPTGPVATELVDRVRNLYRVQLPMAGSYHCPSTGLHFVVTRAVTIEIEFCAWSQFLDKTPLQQSHMVVGPLFDIKAEQGAVTAVYLPHFVSLKDTEASTFDFKVTHFQEHGSRNAR
uniprot
proteins
function
FUNCTION: Probable inactive allele of Nlrp1b, which lacks a CARD domain, suggesting that it is not able to form an inflammasome (PubMed:16429160). Contrary to Nlrp1b allele 1, allele 4 is not activated by B.anthracis lethal toxin and no other activation signal is reported (PubMed:16429160). {ECO:0000269|PubMed:16429160}.
uniprot
proteins
mass_dalton
103119
uniprot
proteins
protein_family
NLRP family
uniprot
proteins
pubmed
16429160
uniprot
proteins
pubmed
23506131
uniprot
proteins
pubmed
32558991
uniprot
proteins
sequence_length
906
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9C000}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9C000}.
uniprot
proteins