DUSP8
entrez
1850
canonical
uniprot
Q13202
canonical
ensembl
ENSG00000184545
resolver
ensembl
ENSG00000273793
resolver
ensembl
ENSG00000278165
resolver
ensembl
ENSG00000291431
resolver
ensp
ENSP00000329539
resolver
ensp
ENSP00000380530
resolver
ensp
ENSP00000479946
resolver
ensp
ENSP00000481775
resolver
ensp
ENSP00000487017
resolver
ensp
ENSP00000487093
resolver
ensp
ENSP00000516909
resolver
ensp
ENSP00000516910
resolver
ensp
ENSP00000562396
resolver
ensp
ENSP00000621711
resolver
ensp
ENSP00000621712
resolver
enst
ENST00000331588
resolver
enst
ENST00000397374
resolver
enst
ENST00000610856
resolver
enst
ENST00000617829
resolver
enst
ENST00000625578
resolver
enst
ENST00000629053
resolver
enst
ENST00000707550
resolver
enst
ENST00000707551
resolver
enst
ENST00000892337
resolver
enst
ENST00000951653
resolver
genesymbol
DUSP8
resolver
genesymbol_syn
C11orf81
resolver
genesymbol_syn
VH5
resolver
hgnc
HGNC:3074
resolver
uniprot
Q86SS8
resolver
uniprot_entry
DUS8_HUMAN
resolver
uniprot_sec
Q86SS8
resolver
amino_acid_sequence
MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPAPPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAPKLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFGDAARQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFAPFGRAGAPGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGRARGEELAALGKQASFSGSVEVIEVS
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues. {ECO:0000250|UniProtKB:O09112}.
uniprot
proteins
mass_dalton
65827
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
24531476
uniprot
proteins
pubmed
7561881
uniprot
proteins
sequence_length
625
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O09112}. Nucleus {ECO:0000250|UniProtKB:O09112}.
uniprot
proteins