Bfsp2
entrez
107993
canonical
uniprot
Q6NVD9
canonical
ensembl
ENSMUSG00000032556
resolver
ensp
ENSMUSP00000116249
resolver
genesymbol
Bfsp2
resolver
uniprot
Q63832
resolver
uniprot
Q6P5N4
resolver
uniprot
Q8VDD6
resolver
uniprot_entry
BFSP2_MOUSE
resolver
uniprot_sec
Q63832
resolver
uniprot_sec
Q6P5N4
resolver
uniprot_sec
Q8VDD6
resolver
amino_acid_sequence
MSKRRVAADLPSGTNSSMPVQRHRVSSLRGTHSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLANVPAPGPERDHTTVEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKSSGGWDALRASWASSYQQVGEAVLENARLLLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGFLSRSYEEDVKVLYKQLAGSELEQADVPMGTGLDDVLETIRVQWERDVEKNRAEAGALLQAKQQTEVVHVSQTQEEKLAAALSVELHDTSRQVQSLQAETESLRALKRGLENSLHDAQHWHDMELQNLGAVVGRLEAELAEIRSETEQQQQERAHLLACKSQLQKDVASYHALLDREENN
uniprot
proteins
function
FUNCTION: Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (PubMed:15037121, PubMed:27559293). Plays a role in maintenance of retinal lens optical clarity (PubMed:12454043). {ECO:0000269|PubMed:12454043, ECO:0000269|PubMed:15037121, ECO:0000269|PubMed:27559293}.
uniprot
proteins
mass_dalton
45740
uniprot
proteins
protein_family
Intermediate filament family
uniprot
proteins
pubmed
12454043
uniprot
proteins
pubmed
12573667
uniprot
proteins
pubmed
14985306
uniprot
proteins
pubmed
15037121
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15744838
uniprot
proteins
pubmed
18178558
uniprot
proteins
pubmed
19029034
uniprot
proteins
pubmed
21745462
uniprot
proteins
pubmed
27559293
uniprot
proteins
pubmed
7679620
uniprot
proteins
sequence_length
416
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q28177}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q28177}; Cytoplasmic side {ECO:0000250|UniProtKB:Q28177}. Cytoplasm {ECO:0000269|PubMed:27559293}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q28177}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q28177}. Note=Expressed primarily at the plasma membrane in peripheral lens fiber cells, however also localizes to the cytoplasm in mature lens fiber cells. {ECO:0000250|UniProtKB:Q28177}.
uniprot
proteins