Mvb12a
entrez
290635
canonical
uniprot
Q6P777
canonical
ensembl
ENSRNOG00000017949
resolver
ensembl
ENSRNOG00055009189
resolver
ensembl
ENSRNOG00060011372
resolver
ensembl
ENSRNOG00065020676
resolver
ensp
ENSRNOP00000094107
resolver
ensp
ENSRNOP00055012471
resolver
ensp
ENSRNOP00060015065
resolver
ensp
ENSRNOP00065028169
resolver
enst
ENSRNOT00000110078
resolver
enst
ENSRNOT00055015554
resolver
enst
ENSRNOT00060019245
resolver
enst
ENSRNOT00065035047
resolver
genesymbol
Mvb12a
resolver
genesymbol_syn
Fam125a
resolver
uniprot
A0A8I6AIU5
resolver
uniprot_entry
A0A8I6AIU5_RAT
resolver
uniprot_entry
MB12A_RAT
resolver
amino_acid_sequence
MDPGTDSTPLAALVWSSASAPPPPGFSAITCTVEGATASFGRGFAQKAGYFLCLSTLGIPENPQDNVVVDMQIVMDKGPLPPGFSTVNDPQDARTSVSKKKRMCVKLMPLGTADVVVSDVKLSGKTKTVPGYLRVGDIGGFAIWCKKSKAPKLVPKPGTLSQDMRGLSLDQPKEPSKGSHPERTLSRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCGPLNLSAFGDLTIKSLADIEKEYNYGFVVEKTAAARLPPSVS
uniprot
proteins
function
FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
28752
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on Tyr-202 upon EGF stimulation. Phosphorylation is required for interaction with CD2AP and CIN85/SH3KBP1 (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
MVB12 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Colocalizes with F-actin. Some fraction may be nuclear (By similarity). {ECO:0000250}.
uniprot
proteins