Mtnap1
entrez
276852
canonical
uniprot
Q6PIX9
canonical
ensembl
ENSMUSG00000041623
resolver
ensp
ENSMUSP00000042025
resolver
ensp
ENSMUSP00000102232
resolver
ensp
ENSMUSP00000190431
resolver
ensp
ENSMUSP00000190433
resolver
ensp
ENSMUSP00000338342
resolver
genesymbol
Mtnap1
resolver
genesymbol_syn
D11Wsu47e
resolver
genesymbol_syn
Gm57859
resolver
uniprot
Q3UTJ1
resolver
uniprot
Q80UV5
resolver
uniprot
Q9CYN0
resolver
uniprot_entry
CQ080_MOUSE
resolver
uniprot_sec
Q3UTJ1
resolver
uniprot_sec
Q80UV5
resolver
uniprot_sec
Q9CYN0
resolver
amino_acid_sequence
MGAAEPRMEVCPYCKKPFKRLKSHLPHCKMRGPSISADQNVSQSKPAALAQKEKSPTRDLTRAKEKELEVDRPKRAVKAETSRASWTAAASPLPEGILGSVRITKAEGENKDQNQFSFQALSQAKPEVTLQRVTTPWSPASDATSPKRELTQDVSESKGSPCPSETEAPSLVSSVEPFLANQDRKYSSTQPHANPATSVGLKLGTVDPQRQKLRVKLLDVPLSDRHSPKSGSHGVQRVTPSVLSREEGSQDGGHLLGVSAHPGNTKTQKSESLLLGLHTGLLGKAPVREHQELGLGMELSQSKGNTENRMSVTNVQEGAGLGQGGKDPITATKAKPHTALELRNVFMPESGNQSLTSPAVTSTPEENAQFCGQSHVPAITLSVGSVRDVLEPTSFYQPHTAQAGHCLMSYSAQYPVPKTFVGHVAAVTSGAPPRSVGLEWFPELYPAYVGLGVLPRRPPPWSLAAQVPPLPTLQGRSVSKVPWWGRSSADSRSLEPLTLTTSSLPLMRLLGAVHKGWVQCNTTIKKSGVGGLTMLFAGYFILCCNWSFKHLKLQHWRK
uniprot
proteins
function
FUNCTION: Critical regulator of mitochondrial DNA (mtDNA) abundance (PubMed:37676315). Binds dsDNA throughout the mitochondrial genome without sequence specificity and controls mtDNA copy number by promoting its replication (By similarity). Also plays important roles in mitochondrial metabolism and cell proliferation (By similarity). {ECO:0000250|UniProtKB:Q9BSJ5, ECO:0000269|PubMed:37676315}.
uniprot
proteins
mass_dalton
60276
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
37676315
uniprot
proteins
sequence_length
558
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9BSJ5}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9BSJ5}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:37676315}. Note=Retained in nucleoids under mtDNA replication stress caused by ddC and EtBr. {ECO:0000250|UniProtKB:Q9BSJ5}.
uniprot
proteins
transmembrane_region
TRANSMEM 528..548; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins