Rnf149
entrez
67702
canonical
uniprot
Q3U2C5
canonical
ensembl
ENSMUSG00000048234
resolver
ensp
ENSMUSP00000050388
resolver
genesymbol
Rnf149
resolver
genesymbol_syn
Greul4
resolver
uniprot
E9QAH5
resolver
uniprot
Q14BF0
resolver
uniprot
Q8CGR2
resolver
uniprot_entry
RN149_MOUSE
resolver
uniprot_sec
E9QAH5
resolver
uniprot_sec
Q14BF0
resolver
uniprot_sec
Q8CGR2
resolver
amino_acid_sequence
MAARRRPAAGVGARDALAVLALALCTPGVGGGALEWYSAMVSIEYVDPQSNLTVWSVSESGRFGESSLREERQGLVGVPRAPAPAEGCAPDTRFVAPGALGNAPWVALVARGGCTFKDKVLAAARRNASAVVVYNLESNGNATEPMSHAGTGNIVVIMISYPKGREIFDLVQKGIPVKMRIEIGTRHMQEFISGQSVVFVAIAFITMMIISLAWLIFYYIQRFLYTGSQFGSQNHRKETKKVIGQLPLHTVKHGEKGIDVDAENCAVCIENFKVKDVIRILPCKHIFHRICIDPWLLDHRTCPMCKLDVIKALGYWGDPEDTQELPTPEAAPGRVSVGNLSVTSQDEERSESNLPSSSSSESGPHRPCLKEDAGEDTALLGAGRSEPQHGGSIC
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation. {ECO:0000250}.
uniprot
proteins
mass_dalton
42553
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
12435366
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
394
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 197..217; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins