Tgfa
entrez
24827
canonical
uniprot
P01134
canonical
ensembl
ENSRNOG00000016182
resolver
ensp
ENSRNOP00000054248
resolver
enst
ENSRNOT00000057441
resolver
genesymbol
Tgfa
resolver
uniprot
A0A8L2QQQ8
resolver
uniprot
Q63749
resolver
uniprot
U5LKN7
resolver
uniprot_entry
A0A8L2QQQ8_RAT
resolver
uniprot_entry
TGFA_RAT
resolver
uniprot_entry
U5LKN7_RAT
resolver
uniprot_sec
Q63749
resolver
amino_acid_sequence
MVPAAGQLALLALGILVAVCQALENSTSPLSDSPVAAAVVSHFNKCPDSHTQYCFHGTCRFLVQEEKPACVCHSGYVGVRCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVLIHCCQVRKHCEWCRALVCRHEKPSALLKGRTACCHSETVV
uniprot
proteins
function
FUNCTION: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
uniprot
proteins
mass_dalton
16960
uniprot
proteins
pubmed
2325647
uniprot
proteins
pubmed
3855503
uniprot
proteins
pubmed
6320373
uniprot
proteins
pubmed
6605968
uniprot
proteins
sequence_length
159
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Transforming growth factor alpha]: Secreted, extracellular space.; SUBCELLULAR LOCATION: [Protransforming growth factor alpha]: Cell membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 98..123; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins