F2RL2
entrez
2151
canonical
uniprot
O00254
canonical
ensembl
ENSG00000164220
resolver
ensp
ENSP00000296641
resolver
ensp
ENSP00000426703
resolver
genesymbol
F2RL2
resolver
genesymbol_syn
PAR3
resolver
hgnc
HGNC:3539
resolver
uniprot
B2R754
resolver
uniprot
B4DQ13
resolver
uniprot
Q52M68
resolver
uniprot
Q7Z3W3
resolver
uniprot_entry
PAR3_HUMAN
resolver
uniprot_sec
B2R754
resolver
uniprot_sec
B4DQ13
resolver
uniprot_sec
Q52M68
resolver
uniprot_sec
Q7Z3W3
resolver
amino_acid_sequence
MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
uniprot
proteins
function
FUNCTION: Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. {ECO:0000269|PubMed:10079109}.
uniprot
proteins
mass_dalton
42508
uniprot
proteins
mutagenesis
MUTAGEN 39; /note="T->P: No proteolytic cleavage by thrombin."; /evidence="ECO:0000269|PubMed:9087410"; MUTAGEN 40; /note="F->A: Altered signal upon thrombin cleavage."; /evidence="ECO:0000269|PubMed:9087410
uniprot
proteins
post_translational_modification
PTM: A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10079109
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16458856
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
9087410
uniprot
proteins
pubmed
9614115
uniprot
proteins
sequence_length
374
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 95..120; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 129..148; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 168..189; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 207..230; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 261..280; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 298..322; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 337..361; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins