Efs
entrez
13644
canonical
uniprot
Q64355
canonical
ensembl
ENSMUSG00000022203
resolver
ensp
ENSMUSP00000022813
resolver
ensp
ENSMUSP00000154657
resolver
enst
ENSMUST00000022813
resolver
enst
ENSMUST00000227037
resolver
genesymbol
Efs
resolver
genesymbol_syn
Sin
resolver
uniprot
A0A2I3BRP5
resolver
uniprot
Q8BSX4
resolver
uniprot_entry
A0A2I3BRP5_MOUSE
resolver
uniprot_entry
EFS_MOUSE
resolver
uniprot_sec
Q8BSX4
resolver
amino_acid_sequence
MAIATSAQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLLPAGPAPKPSLCPASPTQPGSSCPTPERGCEEQEVYVIPPPARPCSASGLPARSCSPSSDSIYKVPRGNGMQLTASRDVAEVYDVPPNILRAPSSCPYDSPASFSCPVAPVVPQPPREDEAPYDVPLALKPPAELERDPEWEGGREPGPPLYAAPSNLKRASALLNLYEAPEELLANGESRDADEGIYDVPLLGPEPPSPEPPVASSSTDLDTVAQLPTRSSPPQHRPRLPSTESLSRRPLPALPVSEAPAPSPAPSPAPGRKGSIQDRPLPPPPPCLPGYGGLKPEGDPECREVANDPAGPHNEYEGIPMAEEYDYVHLKGVDTAQGSRPLDKAFPVDPELLERGLAERKEALSPEEPLVLSTGDLQLLHFYAGQCQSHYSALQAAVAALVASTQANQPPCLFVPHGKRVVVAAHRLVFVGDTLGRLAASAALRAQVGAAGTMLAQTLRATVLAVKGAALGYPSDTAVQEMARCVAELAGQALRFTTLLDGLLP
uniprot
proteins
function
FUNCTION: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
uniprot
proteins
mass_dalton
58973
uniprot
proteins
mutagenesis
MUTAGEN 253; /note="Y->F: Diminishes the ability to induce SRC-mediated activation of luciferase."; /evidence="ECO:0000269|PubMed:8647432
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC. {ECO:0000269|PubMed:8647432}.
uniprot
proteins
protein_family
CAS family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8570184
uniprot
proteins
pubmed
8647432
uniprot
proteins
sequence_length
560
uniprot
proteins