Inmt
entrez
21743
canonical
uniprot
P40936
canonical
ensembl
ENSMUSG00000003477
resolver
ensp
ENSMUSP00000003569
resolver
enst
ENSMUST00000003569
resolver
genesymbol
Inmt
resolver
genesymbol_syn
Temt
resolver
uniprot
Q9CZ50
resolver
uniprot_entry
INMT_MOUSE
resolver
uniprot_sec
Q9CZ50
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by the S-adenosyl-L-methionine analog sinefungin and by the product S-adenosyl-L-homocysteine. {ECO:0000269|PubMed:3350800}.
uniprot
proteins
amino_acid_sequence
MEGKVYIGGEDYEKEFTPKDYLTTYYSFHSGPVAEQEIVKFSLQNLYQTFSTGGVGGDVLIDIGSGPTIYQLLSACEVFREIIVTDYTPQNLQELQKWLKKEPGAYDWSSIVQHACELEGDRSRWQEKEAKLRRTVTRVLRCDVTKTPPLGSAQVPLADCVLTFLAMECACPDIDTYRAALRRLAGLLKPGGHLVTLVTLRFQHYMVGPKKFSGVYLEKEVVEKAIQDAGCQVLKCNCVSLSYSEAYCSHDGLCFVVARKGPSA
uniprot
proteins
ec_number
2.1.1.49
uniprot
proteins
ec_number
2.1.1.96
uniprot
proteins
function
FUNCTION: Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as a thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. {ECO:0000250, ECO:0000269|PubMed:3350800}.
uniprot
proteins
mass_dalton
29460
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
NNMT/PNMT/TEMT family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
3350800
uniprot
proteins
pubmed
7819283
uniprot
proteins
sequence_length
264
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:3350800}.
uniprot
proteins