Nckap5l
entrez
380969
canonical
uniprot
Q6GQX2
canonical
ensembl
ENSMUSG00000023009
resolver
ensp
ENSMUSP00000023747
resolver
ensp
ENSMUSP00000201861
resolver
ensp
ENSMUSP00000331683
resolver
enst
ENSMUST00000023747
resolver
genesymbol
Nckap5l
resolver
genesymbol_syn
Cep169
resolver
uniprot
Q8BX75
resolver
uniprot
Q8R364
resolver
uniprot_entry
NCK5L_MOUSE
resolver
uniprot_sec
Q8BX75
resolver
uniprot_sec
Q8R364
resolver
amino_acid_sequence
MDQPAGGTGKLRASAGEDDSMELSTCQELLHRLRELEAENSALAQANENQRETYERCLDEVANHVVQALLNQKDLREECIKLKKRVFDLERQNQVLSALLQQKLQLTANSLPQIPLTPLQPPSERPTSPAPNVSEGPATSLPSGLCAGQREVCWEQQLRPGGPGPPATPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPTGQGPGSPEPINGEPCGPPQPEPSPWAPYLLLGPGSLGALLHWERVLGGPGEEEGIRQPWASSRAPPSAQGPSSGPHCAPGSSSSSSSDEAGDPNEAPSPDTLLGALARKQLNLGQLLGDTETYLQAFLAGATGPLSGDQPGPGKPNSPDPGPPQVSKSKGLPKSAWGASTPEATRLGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGDAQGPLLPSPARGLKFLKLPPASEKVPSPGGPQLSPQLPRSSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPGSPLPCSAMPDSAQLRPSQSTVSTALSPGPVVSPCFENILDLSRSTFRGSPPEPPPSPLQVPTYPQLTLEVPQTPEVLRSPGAPSPGLPESCPYSGPQEKSMDRAGSESPHASRRTPGGSSKKPGQGSGRRPGDPSHTPLRDRLAALGKLKTGPEGPLGPEKNGVPARSSAEKARALVRSGECAGDVPPSARPLEQPEAKGIFRGAVALGTSSLKQQEPGLTDPGARVYSSHSMGARVDLEPISPRSCLTKVELAKSRLAGALCPQMPRTPAKVPTSAPSLGKPKSPHSSPTKLPSKSPTKVVPRPVVPLGTKEPPKPDKVKGPPWADCGSTVGQPTSPVAGPADPSQGSEGPAPHSAIEEKVMKGIEENVLRLQGQERTPGSEAKHRNTSSIASWFGLKKSKLPALNRRTEATKNKDGAGGGSPLRKEVKTEARKLEAESLNISKLMAKAEDLRRALEEEKAYLSRARPRPGGPATVPSPGLGQAQGQLAGMYQGADTFMQQLLNRVDGKELPPKSWREPKPEYGDFQPVSTDPKSPWPACGPRNGLVGPLQGCGKPGKPSSEPGRREEMPSEDSLAEPVSTTHFTACGSLTRTLDSGIGTFPPPDHSSSGTPSKNLPKTKSLRLDPPPGAPPARPPGLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPGLLTAPPGHRSHQTCPDDPCEDPGPPPPVQLAKNWTFPNTRTAGSSSDPFLCPPRQLEGLPRTPMALPVDRKQSVDPSRTSTPQGPAFGGSRTPSTSDMGEEGRVASGGAPGLETSESLSDSLYDSLSSCGSQG
uniprot
proteins
function
FUNCTION: Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation. {ECO:0000250|UniProtKB:Q9HCH0}.
uniprot
proteins
mass_dalton
138170
uniprot
proteins
post_translational_modification
PTM: CDK1/Cyclin B-dependent phosphorylation mediates its dissociation from centrosomes during mitosis. {ECO:0000250|UniProtKB:Q9HCH0}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9HCH0}. Note=Localizes to microtubule plus ends. Associates with centrosomes during interphase, but dissociates from these structures from the onset of mitosis. {ECO:0000250|UniProtKB:Q9HCH0}.
uniprot
proteins