Gpat2
entrez
296130
canonical
uniprot
D3ZI76
canonical
ensembl
ENSRNOG00000013906
resolver
ensembl
ENSRNOG00055005397
resolver
ensembl
ENSRNOG00060014831
resolver
ensembl
ENSRNOG00065012972
resolver
ensp
ENSRNOP00000018677
resolver
ensp
ENSRNOP00000106144
resolver
ensp
ENSRNOP00055006557
resolver
ensp
ENSRNOP00060020223
resolver
ensp
ENSRNOP00065016386
resolver
enst
ENSRNOT00000155900
resolver
enst
ENSRNOT00055008656
resolver
enst
ENSRNOT00060025363
resolver
enst
ENSRNOT00065021226
resolver
genesymbol
Gpat2
resolver
uniprot_entry
GPAT2_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by N-ethylmaleimide (NEM). {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
amino_acid_sequence
METMLKSNPQMQQRNNHSGQETSLWSSGFGMKMEAITPFLGKYRPFMGRCCQTCTPKSWESLFHRSIMDLGFCNVILVKEENTRFRGWLVRRLCYFLWSLEQHIPTSSDASQMIMENTGVQNILLGKVPGAAGEGQAPDLVKKEVQRILGHIQTTPRPFLLRLFSWALLWFLNRLFLNVQLHKGQMKMVHKAAQEGSPLVFLSTHKSLLDGFLLPFVLFSQGLGVLRVALDSRTCSPALRALLRKLGGLFLPPEANLSLDSSEGILARAVVRATVEQLLTSGQPLLIFLEEAPGYPGPRLSALGQAWLGLVVQAVQAGIVPDATLVPVATAYDLVPDAPCNMTHDLAPLGLWTGALAIFRRLCNCWGCNRRVCVRVHLAQPFSLQEYTINARSCWGSRQTLEHLLQPIVLGECSVVPDTEKEQEWTPPTSLLLALKEEDQLLVRRLSRHVLSASVASSAVMSTAIMATLLLLKHQKGVVLSQLLGEFSWLTEETLLRGFDVGFSGQLRCLAQHTLSLLRAHVVLLRVHQGDLVVVPRPGPGLTHLARLSMELLPTFLSEAVGACAVRGLLAGRVPPEGPWELQGIELLSQNELYRQILLLLHLLPQDLLLPQPCQSSYCYCQEVLDRLIQCGLLVAEETPGSRPACDTGRQHLSAKLLWKPSGDFTDSESDDFEEPGGRCFRLSQQSRCPDFFLFLCRLLSPILKAFAQAATFLHLGQLPDSEVGYSEKLLQFLQACAQEEGIFECADPNLAISAIWTFKDLGVLQQIPSPTGPQLHLSPTFASRDNQDKLEQFIRQFICS
uniprot
proteins
ec_number
2.3.1.15
uniprot
proteins
ec_number
2.3.1.51
uniprot
proteins
function
FUNCTION: Transfers an acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate producing a lysophosphatidic acid (LPA), an essential step for the triacylglycerol (TAG) and glycerophospholipids. In vitro also transfers an acyl-group from acyl-ACP to the LPA producing a phosphatidic acid (PA). Prefers arachidonoyl-CoA as the acyl donor. Required for primary processing step during piRNA biosynthesis. Molecular mechanisms by which it promotes piRNA biosynthesis are unclear and do not involve its acyltransferase activity. {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
mass_dalton
88969
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
protein_family
GPAT/DAPAT family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
22905194
uniprot
proteins
sequence_length
801
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000269|PubMed:22905194}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q14DK4}.
uniprot
proteins
transmembrane_region
TRANSMEM 306..332; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 450..472; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins