ACOT2
entrez
10965
canonical
uniprot
P49753
canonical
ensembl
ENSG00000119673
resolver
ensp
ENSP00000238651
resolver
genesymbol
ACOT2
resolver
genesymbol_syn
PTE2
resolver
genesymbol_syn
PTE2A
resolver
hgnc
HGNC:18431
resolver
uniprot
B3KSA0
resolver
uniprot
Q3I5F8
resolver
uniprot
Q53EK4
resolver
uniprot
Q9NUX4
resolver
uniprot_entry
ACOT2_HUMAN
resolver
uniprot_entry
B3KSA0_HUMAN
resolver
uniprot_sec
Q3I5F8
resolver
uniprot_sec
Q53EK4
resolver
uniprot_sec
Q9NUX4
resolver
amino_acid_sequence
MSNKLLSPHPHSVVLRSEFKMASSPAVLRASRLYQWSLKSSAQFLGSPQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCQTRHERYFLPPGVRREPVRVGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLHYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:10944470, PubMed:16940157). Displays higher activity toward long chain acyl CoAs (C14-C20) (PubMed:10944470, PubMed:16940157). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria (By similarity). {ECO:0000250|UniProtKB:Q9QYR9, ECO:0000269|PubMed:10944470, ECO:0000269|PubMed:16940157}.
uniprot
proteins
mass_dalton
53218
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid metabolism. {ECO:0000305|PubMed:10944470, ECO:0000305|PubMed:16940157}.
uniprot
proteins
protein_family
C/M/P thioester hydrolase family
uniprot
proteins
pubmed
10944470
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16940157
uniprot
proteins
pubmed
19497300
uniprot
proteins
pubmed
7596406
uniprot
proteins
sequence_length
483
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16940157}.
uniprot
proteins