Mapre3
entrez
100732
canonical
uniprot
Q6PER3
canonical
ensembl
ENSMUSG00000029166
resolver
ensp
ENSMUSP00000031058
resolver
ensp
ENSMUSP00000143890
resolver
ensp
ENSMUSP00000309314
resolver
ensp
ENSMUSP00000353978
resolver
ensp
ENSMUSP00000353980
resolver
enst
ENSMUST00000031058
resolver
enst
ENSMUST00000200692
resolver
genesymbol
Mapre3
resolver
genesymbol_syn
EB3
resolver
uniprot
D3Z6G3
resolver
uniprot
Q2UZW7
resolver
uniprot
Q61167
resolver
uniprot_entry
D3Z6G3_MOUSE
resolver
uniprot_entry
MARE3_MOUSE
resolver
uniprot_entry
Q2UZW7_MOUSE
resolver
uniprot_sec
Q61167
resolver
amino_acid_sequence
MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHEADAQILELNQQLLDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY
uniprot
proteins
function
FUNCTION: Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (By similarity). {ECO:0000250|UniProtKB:Q9UPY8}.
uniprot
proteins
mass_dalton
31966
uniprot
proteins
protein_family
MAPRE family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17310996
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21646404
uniprot
proteins
pubmed
24706950
uniprot
proteins
sequence_length
281
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24706950}. Note=Associated with the microtubule network. Detected at the plus end of microtubules. {ECO:0000269|PubMed:24706950}.
uniprot
proteins