SPDYC
entrez
387778
canonical
uniprot
Q5MJ68
canonical
ensembl
ENSG00000204710
resolver
ensp
ENSP00000366390
resolver
enst
ENST00000377185
resolver
genesymbol
SPDYC
resolver
hgnc
HGNC:32681
resolver
uniprot
B2RP32
resolver
uniprot
B7ZMH7
resolver
uniprot_entry
SPDYC_HUMAN
resolver
uniprot_sec
B2RP32
resolver
uniprot_sec
B7ZMH7
resolver
amino_acid_sequence
MSDSQDPTTSPVVTTQVELGGCSRQGGGNGFLRFRQHQEVQAFLSLLEDSFVQEFLSKDPCFQISDKYLLAMVLVYFQRAHLKLSEYTHSSLFLALYLANDMEEDLEGPKCEIFPWALGKDWCLRVGKFLHQRDKLWARMGFRAVVSRQCCEEVMAKEPFHWAWTRDRRPHHGGVQRVCPQVPVRLPRGPGLSPPHCSPCGLPQHCSSHLLKPVSSKCPSLTSECHRPPSQNYLSRVKNAWGGDFLIVLPPQMQLEPGTYSLRIFPKPPARPGH
uniprot
proteins
function
FUNCTION: Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase. {ECO:0000269|PubMed:15611625, ECO:0000269|PubMed:20605920}.
uniprot
proteins
mass_dalton
31078
uniprot
proteins
protein_family
Speedy/Ringo family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15611625
uniprot
proteins
pubmed
20605920
uniprot
proteins
sequence_length
274
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20605920}. Note=Colocalizes with tubulin gamma during interphase. During mitosis, enriched at the spindle poles and the midbody during telophase.
uniprot
proteins