CCK
entrez
885
canonical
uniprot
P06307
canonical
ensembl
ENSG00000187094
resolver
ensp
ENSP00000335657
resolver
ensp
ENSP00000379472
resolver
ensp
ENSP00000409124
resolver
ensp
ENSP00000539328
resolver
ensp
ENSP00000621060
resolver
ensp
ENSP00000621061
resolver
enst
ENST00000334681
resolver
enst
ENST00000396169
resolver
enst
ENST00000434608
resolver
enst
ENST00000869269
resolver
enst
ENST00000951001
resolver
enst
ENST00000951002
resolver
genesymbol
CCK
resolver
hgnc
HGNC:1569
resolver
uniprot
A0A024R2P8
resolver
uniprot
Q6FG82
resolver
uniprot_entry
CCKN_HUMAN
resolver
uniprot_entry
Q6FG82_HUMAN
resolver
uniprot_sec
A0A024R2P8
resolver
amino_acid_sequence
MNSGVCLCVLMAVLAAGALTQPVPPADPAGSGLQRAEEAPRRQLRVSQRTDGESRAHLGALLARYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDFGRRSAEEYEYPS
uniprot
proteins
function
FUNCTION: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. {ECO:0000250|UniProtKB:Q9TS44}.
uniprot
proteins
mass_dalton
12669
uniprot
proteins
mutagenesis
MUTAGEN 97; /note="Y->F: Reduces the quantity of secreted CCK8 by 50%."; /evidence="ECO:0000269|PubMed:11076522
uniprot
proteins
post_translational_modification
PTM: The precursor is cleaved by proteases to produce a number of active cholecystokinins.; PTM: [Cholecystokinin-5]: The precursor is cleaved by ACE, which removes the Gly-Arg-Arg peptide at the C-terminus, leading to mature hormone. {ECO:0000269|PubMed:10336644, ECO:0000269|PubMed:9371719}.
uniprot
proteins
protein_family
Gastrin/cholecystokinin family
uniprot
proteins
pubmed
10336644
uniprot
proteins
pubmed
11076522
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
25326458
uniprot
proteins
pubmed
37453717
uniprot
proteins
pubmed
3856870
uniprot
proteins
pubmed
9371719
uniprot
proteins
sequence_length
115
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:25326458, ECO:0000269|PubMed:37453717}.
uniprot
proteins