PTGIR
entrez
5739
canonical
uniprot
P43119
canonical
ensembl
ENSG00000160013
resolver
ensp
ENSP00000291294
resolver
ensp
ENSP00000543010
resolver
ensp
ENSP00000543013
resolver
ensp
ENSP00000637953
resolver
ensp
ENSP00000637954
resolver
ensp
ENSP00000637955
resolver
ensp
ENSP00000664669
resolver
enst
ENST00000291294
resolver
enst
ENST00000872951
resolver
enst
ENST00000872954
resolver
enst
ENST00000967894
resolver
enst
ENST00000967895
resolver
enst
ENST00000967896
resolver
genesymbol
PTGIR
resolver
genesymbol_syn
PRIPR
resolver
hgnc
HGNC:9602
resolver
uniprot_entry
PI2R_HUMAN
resolver
amino_acid_sequence
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
uniprot
proteins
function
FUNCTION: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
uniprot
proteins
mass_dalton
40956
uniprot
proteins
mutagenesis
MUTAGEN 383; /note="C->S: Abolishes isoprenylation."; /evidence="ECO:0000269|PubMed:11895442
uniprot
proteins
post_translational_modification
PTM: Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. {ECO:0000269|PubMed:11895442}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11895442
uniprot
proteins
pubmed
12488443
uniprot
proteins
pubmed
15194446
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27613955
uniprot
proteins
pubmed
7512962
uniprot
proteins
pubmed
7514139
uniprot
proteins
pubmed
7665161
uniprot
proteins
pubmed
7923647
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 17..38; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 52..76; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 95..115; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 135..158; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 182..208; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 236..260; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 275..295; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins