Gap43
entrez
29423
canonical
uniprot
P07936
canonical
ensembl
ENSRNOG00000001528
resolver
ensembl
ENSRNOG00055003675
resolver
ensembl
ENSRNOG00060008252
resolver
ensembl
ENSRNOG00065008993
resolver
ensp
ENSRNOP00000002091
resolver
ensp
ENSRNOP00055004341
resolver
ensp
ENSRNOP00060010431
resolver
ensp
ENSRNOP00065010763
resolver
enst
ENSRNOT00000002091
resolver
enst
ENSRNOT00055005773
resolver
enst
ENSRNOT00060013682
resolver
enst
ENSRNOT00065014367
resolver
genesymbol
Gap43
resolver
uniprot
A0JPM4
resolver
uniprot_entry
NEUM_RAT
resolver
uniprot_sec
A0JPM4
resolver
amino_acid_sequence
MLCCMRRTKQVEKNDEDQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLKDEKKGDAPAAEAEAKEKDDAPVADGVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAAPSEEKAGSAETESAAKATTDNSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAAKAAQPPTETAESSQAEEEKEAVDEAKPKESARQDEGKEDPEADQEHA
uniprot
proteins
function
FUNCTION: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). {ECO:0000250|UniProtKB:P17677}.
uniprot
proteins
mass_dalton
23603
uniprot
proteins
post_translational_modification
PTM: Phosphorylated (PubMed:1533624, PubMed:8454596, Ref.13). Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity (PubMed:1533624, PubMed:8454596, Ref.13). {ECO:0000269|PubMed:1533624, ECO:0000269|PubMed:8454596, ECO:0000269|Ref.13}.; PTM: Palmitoylated by ZDHHC3 (By similarity). Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2 (By similarity). {ECO:0000250|UniProtKB:P06837, ECO:0000250|UniProtKB:P17677}.
uniprot
proteins
protein_family
Neuromodulin family
uniprot
proteins
pubmed
10982410
uniprot
proteins
pubmed
11948657
uniprot
proteins
pubmed
12106089
uniprot
proteins
pubmed
12957493
uniprot
proteins
pubmed
1533624
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17577668
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2437653
uniprot
proteins
pubmed
3428269
uniprot
proteins
pubmed
3581170
uniprot
proteins
pubmed
8454596
uniprot
proteins
sequence_length
226
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P17677}; Peripheral membrane protein {ECO:0000250|UniProtKB:P17677}; Cytoplasmic side {ECO:0000250|UniProtKB:P17677}. Cell projection, growth cone {ECO:0000269|PubMed:10982410}. Cell projection, growth cone membrane {ECO:0000250|UniProtKB:P17677}; Peripheral membrane protein {ECO:0000250|UniProtKB:P17677}; Cytoplasmic side {ECO:0000250|UniProtKB:P17677}. Synapse {ECO:0000250|UniProtKB:P17677}. Cell projection, filopodium membrane {ECO:0000250|UniProtKB:P17677}; Peripheral membrane protein {ECO:0000250|UniProtKB:P17677}. Perikaryon {ECO:0000269|PubMed:10982410, ECO:0000269|PubMed:12957493}. Cell projection, dendrite {ECO:0000269|PubMed:10982410}. Cell projection, axon {ECO:0000269|PubMed:10982410}. Cytoplasm {ECO:0000269|PubMed:10982410, ECO:0000269|PubMed:12957493}. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes. {ECO:0000250|UniProtKB:P17677}.
uniprot
proteins