LRRC34
entrez
151827
canonical
uniprot
Q8IZ02
canonical
ensembl
ENSG00000171757
resolver
ensp
ENSP00000414635
resolver
ensp
ENSP00000429278
resolver
ensp
ENSP00000429593
resolver
ensp
ENSP00000709174
resolver
ensp
ENSP00000783153
resolver
enst
ENST00000522830
resolver
genesymbol
LRRC34
resolver
hgnc
HGNC:28408
resolver
uniprot
B3KT77
resolver
uniprot
B4DEJ7
resolver
uniprot
B4DHF2
resolver
uniprot
E9PBH2
resolver
uniprot
G3V115
resolver
uniprot
G5E9T7
resolver
uniprot_entry
B3KT77_HUMAN
resolver
uniprot_entry
B4DHF2_HUMAN
resolver
uniprot_entry
G3V115_HUMAN
resolver
uniprot_entry
LRC34_HUMAN
resolver
uniprot_sec
B4DEJ7
resolver
uniprot_sec
E9PBH2
resolver
uniprot_sec
G5E9T7
resolver
amino_acid_sequence
MAAQPPRPVGERSMGSSREAARAPARSPAWASTQASTPGAALAVQRESPESGLQKHYSNLCMEKSQKINPFILHILQEVDEEIKKGLAAGITLNIAGNNRLVPVERVTGEDFWILSKILKNCLYINGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIGPEGGELIAKVLHKNRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNRPILYSEQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQMGCLKPDNTDVEPFVVDGRVYLAEVSNGLKKHYYWTSTYGESYDHSSNAGFALVPVGQQP
uniprot
proteins
function
FUNCTION: Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. {ECO:0000250|UniProtKB:Q9DAM1}.
uniprot
proteins
mass_dalton
51277
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
sequence_length
464
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9DAM1}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9DAM1}. Cytoplasm {ECO:0000250|UniProtKB:Q9DAM1}. Note=As stem cells differentiate, translocates from the nucleolus to the nucleus and then to the cytoplasm. Colocalizes with NPM1 and NCL in the nucleolus. {ECO:0000250|UniProtKB:Q9DAM1}.
uniprot
proteins