Rgs8
entrez
67792
canonical
uniprot
Q8BXT1
canonical
ensembl
ENSMUSG00000042671
resolver
ensp
ENSMUSP00000045715
resolver
ensp
ENSMUSP00000107441
resolver
ensp
ENSMUSP00000107443
resolver
ensp
ENSMUSP00000107445
resolver
ensp
ENSMUSP00000107446
resolver
ensp
ENSMUSP00000175735
resolver
ensp
ENSMUSP00000175736
resolver
ensp
ENSMUSP00000175742
resolver
enst
ENSMUST00000041776
resolver
enst
ENSMUST00000111810
resolver
enst
ENSMUST00000111812
resolver
enst
ENSMUST00000111814
resolver
enst
ENSMUST00000111815
resolver
genesymbol
Rgs8
resolver
uniprot
D3Z289
resolver
uniprot
Q505F2
resolver
uniprot_entry
D3Z289_MOUSE
resolver
uniprot_entry
RGS8_MOUSE
resolver
uniprot_sec
Q505F2
resolver
amino_acid_sequence
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWAESFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPREVNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
uniprot
proteins
function
FUNCTION: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling. {ECO:0000250|UniProtKB:P49804}.
uniprot
proteins
mass_dalton
20963
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
180
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P49804}; Peripheral membrane protein {ECO:0000250|UniProtKB:P49804}; Cytoplasmic side {ECO:0000250|UniProtKB:P49804}. Membrane {ECO:0000250|UniProtKB:P49804}; Peripheral membrane protein {ECO:0000250|UniProtKB:P49804}; Cytoplasmic side {ECO:0000250|UniProtKB:P49804}. Perikaryon {ECO:0000250|UniProtKB:P49804}. Cell projection, dendrite {ECO:0000250|UniProtKB:P49804}. Nucleus {ECO:0000250|UniProtKB:P49804}. Note=Detected in Purkinje cell soma and dendrites. Associated with Purkinje cell membranes. Not detected in Purkinje cell nuclei. Detected in the nucleus after heterologous expression. Recruited to the cell membrane in the presence of GNAO1. {ECO:0000250|UniProtKB:P49804}.
uniprot
proteins