Itpka
entrez
228550
canonical
uniprot
Q8R071
canonical
ensembl
ENSMUSG00000027296
resolver
ensp
ENSMUSP00000028758
resolver
enst
ENSMUST00000028758
resolver
genesymbol
Itpka
resolver
uniprot
A2AQ20
resolver
uniprot_entry
IP3KA_MOUSE
resolver
uniprot_sec
A2AQ20
resolver
activity_regulation
ACTIVITY REGULATION: Activated by calcium/calmodulin. {ECO:0000250|UniProtKB:P23677}.
uniprot
proteins
amino_acid_sequence
MTLPGRPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVTPASPGPPDQEGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFRKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGIVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLRRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER
uniprot
proteins
ec_number
2.7.1.127
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. {ECO:0000250|UniProtKB:P23677}.
uniprot
proteins
mass_dalton
50935
uniprot
proteins
protein_family
Inositol phosphokinase (IPK) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
459
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P23677}.
uniprot
proteins