Ccnc
entrez
51813
canonical
uniprot
Q62447
canonical
ensembl
ENSMUSG00000028252
resolver
ensp
ENSMUSP00000069076
resolver
ensp
ENSMUSP00000100062
resolver
ensp
ENSMUSP00000103875
resolver
ensp
ENSMUSP00000113682
resolver
enst
ENSMUST00000065928
resolver
enst
ENSMUST00000102997
resolver
enst
ENSMUST00000108240
resolver
enst
ENSMUST00000120679
resolver
genesymbol
Ccnc
resolver
uniprot
F6SHK4
resolver
uniprot
F7B6R7
resolver
uniprot
Q0P542
resolver
uniprot
Q3U6Q7
resolver
uniprot
Q3UXL9
resolver
uniprot
Q5XKQ9
resolver
uniprot
Q8CAS3
resolver
uniprot
Q9WUZ4
resolver
uniprot_entry
CCNC_MOUSE
resolver
uniprot_entry
F6SHK4_MOUSE
resolver
uniprot_entry
F7B6R7_MOUSE
resolver
uniprot_entry
Q3U6Q7_MOUSE
resolver
uniprot_entry
Q3UXL9_MOUSE
resolver
uniprot_entry
Q8CAS3_MOUSE
resolver
uniprot_sec
Q0P542
resolver
uniprot_sec
Q5XKQ9
resolver
uniprot_sec
Q9WUZ4
resolver
amino_acid_sequence
MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33241
uniprot
proteins
protein_family
Cyclin C subfamily
uniprot
proteins
protein_family
Cyclin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
283
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins