Kdelr1
entrez
68137
canonical
uniprot
Q99JH8
canonical
ensembl
ENSMUSG00000002778
resolver
ensp
ENSMUSP00000002855
resolver
enst
ENSMUST00000002855
resolver
genesymbol
Kdelr1
resolver
uniprot_entry
ERD21_MOUSE
resolver
amino_acid_sequence
MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA
uniprot
proteins
function
FUNCTION: Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. {ECO:0000250|UniProtKB:P24390}.
uniprot
proteins
mass_dalton
24560
uniprot
proteins
post_translational_modification
PTM: Phosphorylation by PKA at Ser-209 is required for endoplasmic reticulum retention function. {ECO:0000250|UniProtKB:P24390}.
uniprot
proteins
protein_family
ERD2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
212
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:P33946}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250|UniProtKB:P33946}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P33946}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:P33946}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L. {ECO:0000250|UniProtKB:P33946}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..24; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q5ZKX9"; TRANSMEM 33..52; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q5ZKX9"; TRANSMEM 59..79; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q5ZKX9"; TRANSMEM 93..110; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q5ZKX9"; TRANSMEM 117..135; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q5ZKX9"; TRANSMEM 150..168; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q5ZKX9"; TRANSMEM 179..199; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q5ZKX9
uniprot
proteins