KCNA7
entrez
3743
canonical
uniprot
Q96RP8
canonical
ensembl
ENSG00000104848
resolver
ensp
ENSP00000221444
resolver
enst
ENST00000221444
resolver
genesymbol
KCNA7
resolver
hgnc
HGNC:6226
resolver
uniprot
A1KYX7
resolver
uniprot
Q9BYS4
resolver
uniprot_entry
KCNA7_HUMAN
resolver
uniprot_sec
A1KYX7
resolver
uniprot_sec
Q9BYS4
resolver
amino_acid_sequence
MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVTEV
uniprot
proteins
function
FUNCTION: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity). {ECO:0000250|UniProtKB:Q17ST2}.
uniprot
proteins
mass_dalton
50559
uniprot
proteins
protein_family
A (Shaker) (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv1.7/KCNA7 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
11368907
uniprot
proteins
pubmed
11896454
uniprot
proteins
sequence_length
456
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q17ST2}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 144..164; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 241..261; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 276..295; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 312..332; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 373..393; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins