Rnft2
entrez
269695
canonical
uniprot
Q3UF64
canonical
ensembl
ENSMUSG00000032850
resolver
ensp
ENSMUSP00000112903
resolver
ensp
ENSMUSP00000113749
resolver
ensp
ENSMUSP00000120260
resolver
ensp
ENSMUSP00000265494
resolver
ensp
ENSMUSP00000265495
resolver
ensp
ENSMUSP00000265496
resolver
ensp
ENSMUSP00000265497
resolver
ensp
ENSMUSP00000265498
resolver
ensp
ENSMUSP00000265500
resolver
ensp
ENSMUSP00000265503
resolver
genesymbol
Rnft2
resolver
genesymbol_syn
Tmem118
resolver
uniprot
Q8BXI9
resolver
uniprot_entry
RNFT2_MOUSE
resolver
uniprot_sec
Q8BXI9
resolver
amino_acid_sequence
MWLLAAHQVLRKMQRRHSSNTDNIPPERSRSQALSPEASVDEGGVFESLKAETASPPALFSGLAGGLPASPFPAGLVLGSTAGGGDVFIPMPATRDEAGGRSAEGSTYHHRQAHHHFHHGAHRGGSLLQHVGGDHRGHSEEGVDEQPGTPAPALSELKAVISWLQKGLPFILILLAKLCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTMYVLYTFSSQQLYSSLIFLKPNLETLDFFDLLWIVGIADFVLKYITIALKCLIVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDSSNSYFLGGVLIVLYSLCKSFDICGRVGGLRKALKLLCTSQNYGVRATGQQCTEAGAVCAICQAEFRDPMILLCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHLQVY
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase that negatively regulates IL3-dependent cellular responses through IL3RA ubiquitination and degradation by the proteasome, having an anti-inflammatory effect. {ECO:0000269|PubMed:31990690}.
uniprot
proteins
mass_dalton
48856
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
31990690
uniprot
proteins
sequence_length
445
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 184..203; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 216..236; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 257..277; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 331..351; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins