Btbd18
entrez
100270744
canonical
uniprot
A0A0A6YY25
canonical
ensembl
ENSMUSG00000086598
resolver
ensp
ENSMUSP00000142247
resolver
ensp
ENSMUSP00000327678
resolver
enst
ENSMUST00000133437
resolver
genesymbol
Btbd18
resolver
uniprot_entry
BTBDI_MOUSE
resolver
amino_acid_sequence
MCSPASSKILYRNPRFLRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLEMGGLKIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNRECLQPPAAAPISARVVGPKSRPQTPLPVTQTPSPLGAVRLKSLGEEEGAHKKTNLPNADSLSDTQLKKKARVCLTQESRSSPSSQREGPKETKSNPGPTALPSLYPSVDEQLLPRKIRLSRSKPSPHVYTSTPSSILSGPSSMPTAPGRRLWRQRTVSKEAQGVDKQKPGEVRPLQSTPDPSDVGKPAENKKQSPELRAPTSSSVEEGQVGRVKLRKIVNGTCWEVVQEPPLRNTQDSPQILEPSDVEEPSGTLLSSVNEQEIPARIQLCQDSPESPRLQDILLSASHSPDHPMVKSEFGSSPMLTGKESDLNIDCREPYTFDTTLLGQPCEAEQYRITSAAATSELEEIFDFMLCGSDVEPPVGSLESPGAEGCRTPSYHLSETGKNWIEGEEWCLPDMELWPRDLTGLEKEPVSENKEPVEPFSPLVMRSENTESFEPLSPLVMPSEVSREELSLRGSWTPDLEITSSQPLDGQGEKLLHFDSSDPSQRSYNHLSPPCSDWAETGLEVSLGMDDVLCPVPKAVREVSANPEQLDPLPGSSEDEEIDVVDWTVEKKLGPTSVPSVWPDPSSESETEVDILT
uniprot
proteins
function
FUNCTION: Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Acts by facilitating transcription elongation at piRNA loci during pachytene. {ECO:0000269|PubMed:28292424}.
uniprot
proteins
mass_dalton
79464
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28292424
uniprot
proteins
sequence_length
723
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:28292424}.
uniprot
proteins