Abhd10
entrez
303953
canonical
uniprot
Q5I0K5
canonical
ensembl
ENSRNOG00000054334
resolver
ensp
ENSRNOP00000071368
resolver
genesymbol
Abhd10
resolver
uniprot
B1WBW9
resolver
uniprot_entry
ABHDA_RAT
resolver
uniprot_entry
B1WBW9_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by palmostatin-B. {ECO:0000250|UniProtKB:Q9NUJ1}.
uniprot
proteins
amino_acid_sequence
MAAWVPCRKWGWAAVSFGRHRGLIASLARKPPWAWWLSACRQKTTLSFLKRPELPSLAYKRLKGKNPGIIFIPGYLSNMNGKKAVAIEEFCKSIGHAFIRFDYSGVGSSDGNLAECSVGKWRKDVLSILDDIAEGPQILVGSSLGGWLMLHAAIARPEKVIALIGIASATDGVVTQFHSLPVEMQKEIEMKGEWSLPSKYNKEGYYSIPYSFIKEAAHHCLLHSPIPVTCPVRLLHGMKDEIVPWHRSLQVADRVVSPDVDVILRKHSDHRMKETADIHLLICTIDDLIDKLSTVTH
uniprot
proteins
ec_number
3.1.1.93
uniprot
proteins
ec_number
3.1.2.22
uniprot
proteins
function
FUNCTION: Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability. Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate. {ECO:0000250|UniProtKB:Q9NUJ1}.
uniprot
proteins
mass_dalton
33153
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20966424
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9NUJ1}.
uniprot
proteins