SNCG
entrez
6623
canonical
uniprot
O76070
canonical
ensembl
ENSG00000173267
resolver
ensp
ENSP00000344658
resolver
ensp
ENSP00000361087
resolver
enst
ENST00000348795
resolver
enst
ENST00000372017
resolver
genesymbol
SNCG
resolver
genesymbol_syn
BCSG1
resolver
genesymbol_syn
PERSYN
resolver
genesymbol_syn
PRSN
resolver
hgnc
HGNC:11141
resolver
uniprot
A6NM47
resolver
uniprot
F8W754
resolver
uniprot
O15104
resolver
uniprot
Q6FHG5
resolver
uniprot
Q96P61
resolver
uniprot_entry
F8W754_HUMAN
resolver
uniprot_entry
Q6FHG5_HUMAN
resolver
uniprot_entry
SYUG_HUMAN
resolver
uniprot_sec
A6NM47
resolver
uniprot_sec
O15104
resolver
uniprot_sec
Q96P61
resolver
amino_acid_sequence
MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAEEAQSGGD
uniprot
proteins
function
FUNCTION: Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
13331
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases. {ECO:0000269|PubMed:10852916}.
uniprot
proteins
protein_family
Synuclein family
uniprot
proteins
pubmed
10852916
uniprot
proteins
pubmed
11746666
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
9044857
uniprot
proteins
pubmed
9700196
uniprot
proteins
pubmed
9737786
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11746666}. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
uniprot
proteins