Nkiras2
entrez
71966
canonical
uniprot
Q9CR56
canonical
ensembl
ENSMUSG00000017837
resolver
ensp
ENSMUSP00000017981
resolver
ensp
ENSMUSP00000059559
resolver
ensp
ENSMUSP00000102999
resolver
enst
ENSMUST00000017981
resolver
enst
ENSMUST00000051947
resolver
enst
ENSMUST00000107376
resolver
genesymbol
Nkiras2
resolver
uniprot
Q8BWG0
resolver
uniprot_entry
KBRS2_MOUSE
resolver
uniprot_sec
Q8BWG0
resolver
amino_acid_sequence
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGLRDGAELPKHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFIYLASKMTQPQSKSAFPLSRKNKGSGSLDG
uniprot
proteins
function
FUNCTION: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
21494
uniprot
proteins
protein_family
KappaB-Ras subfamily
uniprot
proteins
protein_family
Ras family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
191
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins