P0CB49
uniprot
P0CB49
canonical
amino_acid_sequence
MYPNWGRYGGSSHYPPPPVPPPPPPVALPEASPGPGYSSSTAPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMIHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPSSAQPYLPPAQPSPSKPQLPPPPPSIPSGNKTTIQQEPLETGAKNKNAEQKQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGLVTAKDVPEPIKEEAPVPATSQIAEPLAAEEPPLPPPNEEMPPPLPPEEPQNNSSEMSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQRHTQLQQILQQYQQVIQHSPHIQTMSLDVQLRHYEMQQQQFQRLYQEWEREFQLWEEQLHSYPHKDQLEEYEKQWKSWQGHMRATQTYLQEKVTSFQAVKNQYMGNMAMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPSTIPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAVLPPPSLSSAGPPPVLPPPSLSGAPPVLPLPPLSSATPPPGIPPPGVPQGMPPQLTAPVPPASSSQNSQVPEKPRQALLPTPVSFGSTPPSPYHPPPQSEQGNSKPLNKVFSSEQGLGESSSALSQSVIAAKDTPVKSGGLLADPPKGSFLEGPRGPREQKEQLQKLKDFGSEPQTADHLPPPDSRLQNTSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSCVPMTRPPVPIPPPPPPPPPPPPPPPVIKPKTSSVKQERWDEDSFFGLWDTNDDQGLNSEFKRDTAAIPSAPVLPPPPVHPSIPPPGPMPMGMPPMSKPPPVQHTVDYGHGRDMPTNKVEQIPYGERITLRPDPLPERSAFDADHAGQRDRYDRDRDREPYFDRQSNMTDHRDFKRDRETHRDRDRVLDYERDRFDRERRPRDDRNQSYRDKKDHSSSRRGGFDRPSYDRKSDRPPYEGPPMFGGERRTYPEERMPLPAPSLGHQPPPVPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFIAEVEKEEKDPDSGKKVKKKVMEYEYEADMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMAEHWEAAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEDQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYETRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAERALNRTKYI
uniprot
proteins
function
FUNCTION: Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. {ECO:0000250}.
uniprot
proteins
mass_dalton
154270
uniprot
proteins
pubmed
14724321
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
17890166
uniprot
proteins
sequence_length
1376
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14724321, ECO:0000269|PubMed:17890166}. Nucleus speckle {ECO:0000250}. Note=Migrates to nucleolar caps upon blockage of transcription.
uniprot
proteins