Prkcsh
entrez
19089
canonical
uniprot
O08795
canonical
ensembl
ENSMUSG00000003402
resolver
ensp
ENSMUSP00000003493
resolver
ensp
ENSMUSP00000110987
resolver
ensp
ENSMUSP00000149936
resolver
ensp
ENSMUSP00000215571
resolver
ensp
ENSMUSP00000215603
resolver
ensp
ENSMUSP00000215605
resolver
genesymbol
Prkcsh
resolver
uniprot
Q3U518
resolver
uniprot
Q921X2
resolver
uniprot_entry
GLU2B_MOUSE
resolver
uniprot_entry
Q3U518_MOUSE
resolver
uniprot_sec
Q921X2
resolver
amino_acid_sequence
MLLLLLLLLPLCWAVEVKRPRGVSLSNHHFYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKGRKEKESLQQLAEVTREGFRLKKILIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRAAKEEAERPEKEAKDQHRKLWEEQQAAAKARREQERAASAFQELDDNMDGMVSLAELQTHPELDTDGDGALSEEEAQALLSGDTQTDTTSFYDRVWAAIRDKYRSEVPPTDIPVPEETEPKEEKPPVLPPTEEEEEEEEEPEEEEEEEEEEEEAPPPLQPPQPPSPTEDEKMPPYDEETQAIIDAAQEARSKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKHGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEAPSDGDHDEL
uniprot
proteins
function
FUNCTION: Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:27462106, PubMed:9148925). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (PubMed:21685914). {ECO:0000269|PubMed:21685914, ECO:0000269|PubMed:27462106, ECO:0000269|PubMed:9148925}.
uniprot
proteins
mass_dalton
58793
uniprot
proteins
pathway_participation
PATHWAY: Glycan metabolism; N-glycan metabolism. {ECO:0000269|PubMed:27462106}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21685914
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
27462106
uniprot
proteins
pubmed
9148925
uniprot
proteins
sequence_length
521
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000255|PROSITE-ProRule:PRU10138}.
uniprot
proteins