Atad1
entrez
67979
canonical
uniprot
Q9D5T0
canonical
ensembl
ENSMUSG00000013662
resolver
ensp
ENSMUSP00000069962
resolver
ensp
ENSMUSP00000157772
resolver
ensp
ENSMUSP00000157842
resolver
ensp
ENSMUSP00000158237
resolver
enst
ENSMUST00000070210
resolver
enst
ENSMUST00000235412
resolver
enst
ENSMUST00000236011
resolver
enst
ENSMUST00000236985
resolver
genesymbol
Atad1
resolver
uniprot
Q3U8V2
resolver
uniprot
Q9D7A4
resolver
uniprot_entry
ATAD1_MOUSE
resolver
uniprot_sec
Q3U8V2
resolver
uniprot_sec
Q9D7A4
resolver
amino_acid_sequence
MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPTRKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQNVLTHVCLD
uniprot
proteins
ec_number
7.4.2.-
uniprot
proteins
function
FUNCTION: Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria (By similarity). Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane (By similarity). Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory (PubMed:21496646). Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (PubMed:21496646). {ECO:0000250|UniProtKB:P28737, ECO:0000250|UniProtKB:Q8NBU5, ECO:0000269|PubMed:21496646}.
uniprot
proteins
mass_dalton
40744
uniprot
proteins
protein_family
AAA ATPase family
uniprot
proteins
protein_family
MSP1 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17208939
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17768142
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21496646
uniprot
proteins
sequence_length
361
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8NBU5}; Single-pass membrane protein {ECO:0000255}. Peroxisome membrane {ECO:0000269|PubMed:17768142}; Single-pass membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000269|PubMed:21496646}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 16..32; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins