Eef1akmt3
entrez
100504608
canonical
uniprot
D3YWP0
canonical
ensembl
ENSMUSG00000080115
resolver
ensp
ENSMUSP00000111939
resolver
enst
ENSMUST00000116231
resolver
genesymbol
Eef1akmt3
resolver
genesymbol_syn
Fam119b
resolver
genesymbol_syn
Mettl21b
resolver
uniprot_entry
EFMT3_MOUSE
resolver
amino_acid_sequence
MASSRTDPETEPESVFPREIRLFTDSYSESSRFCFCGHELSITQNFGSRLGVAARVWDAALSLCDYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPVALEQIQDNVHANVPPGGRARVCALSWGIDQHVFPGNYDLVLGADIVYLEPTFPLLLGTLRHLCGPHGTIYLASKMRAEHGAETFFRRLLPQHFHLELAQRDEDVNVNIYRARHREVAPAGQHPFC
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Protein-lysine methyltransferase that selectively mono-, di- and trimethylates 'Lys-165' of the translation elongation factors EEF1A1 and EEF1A2 in an aminoacyl-tRNA and GTP-dependent manner (By similarity). EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation (PubMed:28108655). {ECO:0000250|UniProtKB:Q96AZ1, ECO:0000269|PubMed:28108655}.
uniprot
proteins
mass_dalton
25675
uniprot
proteins
protein_family
METTL21 family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
28108655
uniprot
proteins
sequence_length
232
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96AZ1}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q96AZ1}.
uniprot
proteins