HP1BP3
entrez
50809
canonical
uniprot
Q5SSJ5
canonical
ensembl
ENSG00000127483
resolver
ensp
ENSP00000312625
resolver
ensp
ENSP00000402754
resolver
ensp
ENSP00000403039
resolver
ensp
ENSP00000522107
resolver
ensp
ENSP00000522109
resolver
ensp
ENSP00000656417
resolver
ensp
ENSP00000778976
resolver
ensp
ENSP00000778978
resolver
genesymbol
HP1BP3
resolver
hgnc
HGNC:24973
resolver
uniprot
A6NI71
resolver
uniprot
A8K5D7
resolver
uniprot
B3KMZ8
resolver
uniprot
B4E210
resolver
uniprot
Q05BI0
resolver
uniprot
Q5SSJ6
resolver
uniprot
Q5SWC6
resolver
uniprot
Q6PIM9
resolver
uniprot
Q8NDF0
resolver
uniprot
Q9UHY0
resolver
uniprot_entry
HP1B3_HUMAN
resolver
uniprot_sec
A6NI71
resolver
uniprot_sec
A8K5D7
resolver
uniprot_sec
B3KMZ8
resolver
uniprot_sec
B4E210
resolver
uniprot_sec
Q05BI0
resolver
uniprot_sec
Q5SSJ6
resolver
uniprot_sec
Q5SWC6
resolver
uniprot_sec
Q6PIM9
resolver
uniprot_sec
Q8NDF0
resolver
uniprot_sec
Q9UHY0
resolver
amino_acid_sequence
MATDTSQGELVHPKALPLIVGAQLIHADKLGEKVEDSTMPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQVKGKGASGSFVVVQKSRKTPQKSRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYYPKLRVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKKSGEKPLLGGSLMEYAILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQISGKGFSGTFQLCFPYYPSPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKKSFRVKK
uniprot
proteins
function
FUNCTION: Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal (PubMed:25100860). {ECO:0000269|PubMed:24830416, ECO:0000269|PubMed:25100860}.
uniprot
proteins
mass_dalton
61207
uniprot
proteins
pubmed
10931946
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19367720
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20042602
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24830416
uniprot
proteins
pubmed
25100860
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
553
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24830416}. Chromosome {ECO:0000269|PubMed:20042602, ECO:0000269|PubMed:24830416}. Note=localized in nuclei but not in nucleoli in interphase. Colocalized with chromosomes in mitosis, with a gradually increased during G1 progression and a maximum level during late G1 phase (G1/S). {ECO:0000269|PubMed:24830416}.
uniprot
proteins