P2ry1
entrez
18441
canonical
uniprot
P49650
canonical
ensembl
ENSMUSG00000027765
resolver
ensp
ENSMUSP00000029331
resolver
ensp
ENSMUSP00000141371
resolver
ensp
ENSMUSP00000142006
resolver
enst
ENSMUST00000029331
resolver
enst
ENSMUST00000193201
resolver
enst
ENSMUST00000193943
resolver
genesymbol
P2ry1
resolver
uniprot
Q544J5
resolver
uniprot
Q8BMJ5
resolver
uniprot_entry
P2RY1_MOUSE
resolver
uniprot_entry
Q544J5_MOUSE
resolver
uniprot_entry
Q8BMJ5_MOUSE
resolver
amino_acid_sequence
MTEVPWSVVPNGTDAAFLAGLGSLWGNSTVASTAAVSSSFQCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAIYVSVLVWLIVVVAISPILFYSGTGTRKNKTVTCYDTTSNDYLRSYFIYSMCTTVAMFCIPLVLILGCYGLIVKALIYNDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCDFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEEMTLNILSEFKQNGDTSL
uniprot
proteins
function
FUNCTION: Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. {ECO:0000269|PubMed:10606627}.
uniprot
proteins
mass_dalton
42213
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10606627
uniprot
proteins
pubmed
7779087
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P47900}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P47900}.
uniprot
proteins
transmembrane_region
TRANSMEM 52..74; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:P47900"; TRANSMEM 88..109; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:P47900"; TRANSMEM 126..147; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:P47900"; TRANSMEM 167..188; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:P47900"; TRANSMEM 215..237; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:P47900"; TRANSMEM 261..284; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:P47900"; TRANSMEM 304..325; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:P47900
uniprot
proteins