FAIM2
entrez
23017
canonical
uniprot
Q9BWQ8
canonical
ensembl
ENSG00000135472
resolver
ensp
ENSP00000321951
resolver
ensp
ENSP00000446771
resolver
genesymbol
FAIM2
resolver
genesymbol_syn
KIAA0950
resolver
genesymbol_syn
LFG
resolver
genesymbol_syn
LFG2
resolver
genesymbol_syn
NMP35
resolver
genesymbol_syn
TMBIM2
resolver
hgnc
HGNC:17067
resolver
uniprot
A8K1W6
resolver
uniprot
B3KR08
resolver
uniprot
Q9UJY9
resolver
uniprot
Q9Y2F7
resolver
uniprot_entry
LFG2_HUMAN
resolver
uniprot_sec
A8K1W6
resolver
uniprot_sec
B3KR08
resolver
uniprot_sec
Q9UJY9
resolver
uniprot_sec
Q9Y2F7
resolver
amino_acid_sequence
MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE
uniprot
proteins
function
FUNCTION: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. {ECO:0000269|PubMed:10535980, ECO:0000269|PubMed:17635665}.
uniprot
proteins
mass_dalton
35110
uniprot
proteins
protein_family
BI1 family
uniprot
proteins
protein_family
LFG subfamily
uniprot
proteins
pubmed
10231032
uniprot
proteins
pubmed
10535980
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
16964429
uniprot
proteins
pubmed
17635665
uniprot
proteins
pubmed
19784873
uniprot
proteins
pubmed
20336373
uniprot
proteins
pubmed
20336406
uniprot
proteins
sequence_length
316
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane raft {ECO:0000269|PubMed:17635665}. Postsynaptic cell membrane {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 138..158; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 250..270; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 290..310; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins