TTLL2
entrez
83887
canonical
uniprot
Q9BWV7
canonical
ensembl
ENSG00000120440
resolver
ensp
ENSP00000239587
resolver
ensp
ENSP00000424130
resolver
ensp
ENSP00000497040
resolver
enst
ENST00000239587
resolver
enst
ENST00000515138
resolver
enst
ENST00000649884
resolver
genesymbol
TTLL2
resolver
genesymbol_syn
C6orf104
resolver
hgnc
HGNC:21211
resolver
uniprot
A0A3B3IRU1
resolver
uniprot
B2RB11
resolver
uniprot
B3KS77
resolver
uniprot
Q7Z6R8
resolver
uniprot
Q86X22
resolver
uniprot_entry
A0A3B3IRU1_HUMAN
resolver
uniprot_entry
TTLL2_HUMAN
resolver
uniprot_sec
B2RB11
resolver
uniprot_sec
B3KS77
resolver
uniprot_sec
Q7Z6R8
resolver
uniprot_sec
Q86X22
resolver
amino_acid_sequence
MRGRDLCSSTQSQALGSLRTTTPAFTLNIPSEANHTEQPPAGLGARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGLRNEGREASNATHGNSNIDAAKSDRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGLNVKRIIQELQKLMNKQHS
uniprot
proteins
ec_number
6.-.-.-
uniprot
proteins
function
FUNCTION: Probable tubulin polyglutamylase that generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins (By similarity). Similar to TTLL1, may acquire enzymatic activity only in complex with other proteins as it is most likely lacking domains important for autonomous activity (By similarity). Probably involved in the side-chain initiation step of the polyglutamylation reaction rather than the elongation step (By similarity). {ECO:0000250|UniProtKB:A4Q9E4, ECO:0000250|UniProtKB:Q91V51}.
uniprot
proteins
mass_dalton
67336
uniprot
proteins
protein_family
Tubulin--tyrosine ligase family
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
592
uniprot
proteins