GIPR
entrez
2696
canonical
uniprot
P48546
canonical
ensembl
ENSG00000010310
resolver
ensp
ENSP00000305321
resolver
ensp
ENSP00000467342
resolver
ensp
ENSP00000467494
resolver
ensp
ENSP00000623393
resolver
ensp
ENSP00000623394
resolver
enst
ENST00000585889
resolver
genesymbol
GIPR
resolver
hgnc
HGNC:4271
resolver
uniprot
B7WP14
resolver
uniprot
B7ZKQ0
resolver
uniprot
K7EPD9
resolver
uniprot
Q14401
resolver
uniprot
Q16400
resolver
uniprot
Q52M04
resolver
uniprot
Q9UPI1
resolver
uniprot_entry
GIPR_HUMAN
resolver
uniprot_entry
K7EPD9_HUMAN
resolver
uniprot_sec
B7WP14
resolver
uniprot_sec
B7ZKQ0
resolver
uniprot_sec
Q14401
resolver
uniprot_sec
Q16400
resolver
uniprot_sec
Q52M04
resolver
uniprot_sec
Q9UPI1
resolver
amino_acid_sequence
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
uniprot
proteins
function
FUNCTION: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. {ECO:0000269|PubMed:7556958, ECO:0000269|PubMed:7589426}.
uniprot
proteins
mass_dalton
53157
uniprot
proteins
post_translational_modification
PTM: N-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER. {ECO:0000269|PubMed:22412906}.
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17715056
uniprot
proteins
pubmed
22412906
uniprot
proteins
pubmed
7556958
uniprot
proteins
pubmed
7589426
uniprot
proteins
pubmed
8575774
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 139..161; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 170..189; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 218..242; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 255..278; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 294..319; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 342..362; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 378..398; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins