Stau2
entrez
29819
canonical
uniprot
Q8CJ67
canonical
ensembl
ENSMUSG00000025920
resolver
ensp
ENSMUSP00000027052
resolver
ensp
ENSMUSP00000118489
resolver
ensp
ENSMUSP00000122410
resolver
ensp
ENSMUSP00000123827
resolver
ensp
ENSMUSP00000124303
resolver
ensp
ENSMUSP00000124505
resolver
ensp
ENSMUSP00000277127
resolver
ensp
ENSMUSP00000277128
resolver
ensp
ENSMUSP00000277129
resolver
ensp
ENSMUSP00000277130
resolver
ensp
ENSMUSP00000277141
resolver
ensp
ENSMUSP00000277152
resolver
enst
ENSMUST00000128957
resolver
enst
ENSMUST00000149320
resolver
genesymbol
Stau2
resolver
uniprot
D3Z6D2
resolver
uniprot
Q8BSY8
resolver
uniprot
Q8CJ66
resolver
uniprot
Q8R175
resolver
uniprot
Q91Z19
resolver
uniprot
Q9D5N7
resolver
uniprot_entry
D3Z6D2_MOUSE
resolver
uniprot_entry
STAU2_MOUSE
resolver
uniprot_sec
Q8BSY8
resolver
uniprot_sec
Q8CJ66
resolver
uniprot_sec
Q8R175
resolver
uniprot_sec
Q91Z19
resolver
uniprot_sec
Q9D5N7
resolver
amino_acid_sequence
MANPKEKTPVCLVNELARFHSIQPQYKLLNESGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALTESTLPKPVQKPPKSNVNNNPGSITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRGMYNQRYHCPMPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPEKSPQNGESGKEMDDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPDYGQGMNPISRLAQIQQARKEKEPDYILLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTSLQDPLDKTGENKGWSGPKPGFPEPTNNTPKGILHLSPDVYQEMEASRHRVTSGTTLSYLSPKDMNQPSSSFFSVSPSSTSSATVARELLMNGTSPTAEAIGLKGSSPTSPCSSVQPSKQLEYLARIQGFQAALSALKQFSEQGLESIDGAVNVEKGSLEKQAKHLREKADNNQAKPASISQDCKKSKSAI
uniprot
proteins
function
FUNCTION: RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body (By similarity). {ECO:0000250|UniProtKB:Q68SB1}.
uniprot
proteins
mass_dalton
62535
uniprot
proteins
mutagenesis
MUTAGEN 235; /note="H->A: Abrogates RNA-binding by DRBM 3 and interaction with XPO5 and nuclear export; when associated with A-237."; /evidence="ECO:0000269|PubMed:15166236"; MUTAGEN 237; /note="K->A: Abrogates RNA-binding by DRBM 3 and interaction with XPO5 and nuclear export; when associated with A-235."; /evidence="ECO:0000269|PubMed:15166236"; MUTAGEN 273..274; /note="KK->AA: Prevents nuclear localization of mutants lacking DRBM 3 function; when associated with 289-AAA-291."; /evidence="ECO:0000269|PubMed:15166236"; MUTAGEN 289..291; /note="KKR->AAA: Prevents nuclear localization of mutants lacking DRBM 3 function; when associated with 257-AA-258."; /evidence="ECO:0000269|PubMed:15166236
uniprot
proteins
pubmed
12140260
uniprot
proteins
pubmed
12859680
uniprot
proteins
pubmed
15166236
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
570
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15166236}. Nucleus {ECO:0000269|PubMed:15166236}. Nucleus, nucleolus {ECO:0000269|PubMed:15166236}. Endoplasmic reticulum {ECO:0000269|PubMed:15166236}. Note=Shuttles between the nucleolus, nucleus and the cytoplasm. Nuclear export of isoform 1 is independent of XPO1/CRM1 and requires the exportin XPO5. Nuclear export of isoform 2 and isoform 3 can occur by both XPO1/CRM1-dependent and XPO1/CRM1-independent pathways. May also be found in large cytoplasmic ribonucleoprotein (RNP) granules which are present in the actin rich regions of myelinating processes and associated with microtubules, polysomes and the endoplasmic reticulum. Also recruited to stress granules (SGs) upon inhibition of translation or oxidative stress. These structures are thought to harbor housekeeping mRNAs when translation is aborted.
uniprot
proteins