Degs1
entrez
58970
canonical
uniprot
Q5XIF5
canonical
ensembl
ENSRNOG00000003223
resolver
ensembl
ENSRNOG00055012633
resolver
ensembl
ENSRNOG00060007594
resolver
ensembl
ENSRNOG00065017756
resolver
ensp
ENSRNOP00000004319
resolver
ensp
ENSRNOP00055017474
resolver
ensp
ENSRNOP00060009497
resolver
ensp
ENSRNOP00065023608
resolver
enst
ENSRNOT00000004319
resolver
enst
ENSRNOT00055021560
resolver
enst
ENSRNOT00060012533
resolver
enst
ENSRNOT00065029722
resolver
genesymbol
Degs1
resolver
genesymbol_syn
Degs
resolver
genesymbol_syn
Des1
resolver
uniprot
Q564G4
resolver
uniprot
Q91XI6
resolver
uniprot_entry
DEGS1_RAT
resolver
uniprot_sec
Q564G4
resolver
uniprot_sec
Q91XI6
resolver
amino_acid_sequence
MGNRVSREEFEWVYTDQPHAARRQEILAKYPEIKSLMKPDPNLIWIVTSMLLVQLASFYLVKDLDWKWLMFWSYAFGSCLNHSMTLAIHEISHNFPFGHHKAMWNRWFGMFANLSLGVPYSISFKRYHMDHHRYLGADGIDVDIPTDFEGWFFCTTLRKLVWVILQPLFYAFRPLFINPKPITHLEVINTVIQVTFDVLVYYVFGVKSLVYMLAASLLGLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNVPGKNLPLVRKIASEYYDNLPHYNSWIRVLYDFVMDDTISPYSRMKRPPKGNEIQE
uniprot
proteins
ec_number
1.14.19.17
uniprot
proteins
ec_number
5.2.1.-
uniprot
proteins
function
FUNCTION: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (By similarity). Catalyzes the equilibrium isomerization of retinols (By similarity). {ECO:0000250|UniProtKB:O09005, ECO:0000250|UniProtKB:Q5F3C1}.
uniprot
proteins
mass_dalton
38055
uniprot
proteins
post_translational_modification
PTM: Myristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels. {ECO:0000250|UniProtKB:O15121}.
uniprot
proteins
protein_family
DEGS subfamily
uniprot
proteins
protein_family
Fatty acid desaturase type 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:O15121}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O15121}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O15121}.
uniprot
proteins
transmembrane_region
TRANSMEM 41..61; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 152..172; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 184..204; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 210..230; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins