MTNAP1
entrez
55028
canonical
uniprot
Q9BSJ5
canonical
ensembl
ENSG00000141219
resolver
ensp
ENSP00000255557
resolver
ensp
ENSP00000268942
resolver
ensp
ENSP00000351937
resolver
ensp
ENSP00000396970
resolver
ensp
ENSP00000440551
resolver
ensp
ENSP00000464132
resolver
ensp
ENSP00000563576
resolver
ensp
ENSP00000604426
resolver
ensp
ENSP00000694914
resolver
ensp
ENSP00000694915
resolver
ensp
ENSP00000775419
resolver
enst
ENST00000255557
resolver
genesymbol
MTNAP1
resolver
hgnc
HGNC:29601
resolver
uniprot
A8K9X3
resolver
uniprot
I3L072
resolver
uniprot
Q5JB45
resolver
uniprot
Q6YAU3
resolver
uniprot
Q9H0L9
resolver
uniprot
Q9H5E6
resolver
uniprot
Q9NWN5
resolver
uniprot_entry
CQ080_HUMAN
resolver
uniprot_entry
I3L072_HUMAN
resolver
uniprot_sec
A8K9X3
resolver
uniprot_sec
Q5JB45
resolver
uniprot_sec
Q6YAU3
resolver
uniprot_sec
Q9H0L9
resolver
uniprot_sec
Q9H5E6
resolver
uniprot_sec
Q9NWN5
resolver
amino_acid_sequence
MSDNPPRMEVCPYCKKPFKRLKSHLPYCKMIGPTIPTDQKVYQSKPATLPRAKKMKGPIKDLIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGLERAATTKADKDIKNPIQPSFKMLKNTKPMTTFQEETKAQFYASEKTSPKRELAKDLPKSGESRCNPSEAGASLLVGSIEPSLSNQDRKYSSTLPNDVQTTSGDLKLDKIDPQRQELLVKLLDVPTGDCHISPKNVSDGVKRVRTLLSNERDSKGRDHLSGVPTDVTVTETPEKNTESLILSLKMSSLGKIQVMEKQEKGLTLGVETCGSKGNAEKSMSATEKQERTVMSHGCENFNTRDSVTGKESQGERPHLSLFIPRETTYQFHSVSQSSSQSLASLATTFLQEKKAEAQNHHCVPDVKALMESPEGQLSLEPKSDSQFQASHTGCQSPLCSAQRHTPQSPFTNHAAAAGRKTLRSCMGLEWFPELYPGYLGLGVLPGKPQCWNAMTQKPQLISPQGERLSQVSLLERSSTHIRSLEPPAGLTTSNFSLMRLLGAVQKGWIRCNTTIRKSGFGGITMLFTGYFVLCCSWSFRRLKKLCRPLPWKSTVPPCIGVAKTTGDCRSKTCLD
uniprot
proteins
function
FUNCTION: Critical regulator of mitochondrial DNA (mtDNA) abundance (PubMed:37676315). Binds dsDNA throughout the mitochondrial genome without sequence specificity and controls mtDNA copy number by promoting its replication (PubMed:37676315). Also plays important roles in mitochondrial metabolism and cell proliferation (PubMed:37676315). {ECO:0000269|PubMed:37676315}.
uniprot
proteins
mass_dalton
67315
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
37401363
uniprot
proteins
pubmed
37676315
uniprot
proteins
sequence_length
609
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:37401363}; Single-pass type I membrane protein {ECO:0000305}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:37401363, ECO:0000269|PubMed:37676315}. Note=Retained in nucleoids under mtDNA replication stress caused by ddC and EtBr. {ECO:0000269|PubMed:37401363}.
uniprot
proteins
transmembrane_region
TRANSMEM 553..573; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins