SERTM2
entrez
401613
canonical
uniprot
A0A1B0GWG4
canonical
ensembl
ENSG00000260802
resolver
ensp
ENSP00000490917
resolver
enst
ENST00000569275
resolver
genesymbol
SERTM2
resolver
hgnc
HGNC:48576
resolver
uniprot_entry
SRTM2_HUMAN
resolver
amino_acid_sequence
MMEAHFKYHGNLTGRAHFPTLATEVDTSSDKYSNLYMYVGLFLSLLAILLILLFTMLLRLKHVISPINSDSTESVPQFTDVEMQSRIPTP
uniprot
proteins
function
FUNCTION: Promotes GDNF-mediated spinal cord motor neuron subtype specification, ensuring the maintenance of ETV4-expressing motor neurons. Affects the resting membrane potential and excitability of motor neurons. {ECO:0000250|UniProtKB:A0A1B0GSN8}.
uniprot
proteins
mass_dalton
10219
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:A0A1B0GSN8}.
uniprot
proteins
protein_family
SERTM family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
40108406
uniprot
proteins
sequence_length
90
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:40108406}. Cell membrane {ECO:0000250|UniProtKB:A0A1B0GSN8}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 38..58; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins