CDC123
entrez
8872
canonical
uniprot
O75794
canonical
ensembl
ENSG00000151465
resolver
ensp
ENSP00000281141
resolver
ensp
ENSP00000602783
resolver
enst
ENST00000281141
resolver
genesymbol
CDC123
resolver
genesymbol_syn
C10orf7
resolver
genesymbol_syn
D123
resolver
hgnc
HGNC:16827
resolver
uniprot
A8JZZ7
resolver
uniprot
Q14107
resolver
uniprot
Q5T0L4
resolver
uniprot
Q5T0L5
resolver
uniprot
Q5T0L7
resolver
uniprot
Q5T0L8
resolver
uniprot
Q5T0L9
resolver
uniprot_entry
CD123_HUMAN
resolver
uniprot_sec
A8JZZ7
resolver
uniprot_sec
Q14107
resolver
uniprot_sec
Q5T0L4
resolver
uniprot_sec
Q5T0L5
resolver
uniprot_sec
Q5T0L7
resolver
uniprot_sec
Q5T0L8
resolver
uniprot_sec
Q5T0L9
resolver
amino_acid_sequence
MKKEHVLHCQFSAWYPFFRGVTIKSVILPLPQNVKDYLLDDGTLVVSGRDDPPTHSQPDSDDEAEEIQWSDDENTATLTAPEFPEFATKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEIRRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEELISENNLNGDFSEVDAQEQDSPAFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD
uniprot
proteins
function
FUNCTION: ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity). {ECO:0000250|UniProtKB:Q05791, ECO:0000269|PubMed:35031321, ECO:0000269|PubMed:37507029}.
uniprot
proteins
mass_dalton
39135
uniprot
proteins
mutagenesis
MUTAGEN 233; /note="D->A: Severely disrupts assembly factor activity."; /evidence="ECO:0000269|PubMed:37507029"; MUTAGEN 246; /note="D->A: Severely disrupts assembly factor activity."; /evidence="ECO:0000269|PubMed:37507029
uniprot
proteins
protein_family
CDC123 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
31836389
uniprot
proteins
pubmed
35031321
uniprot
proteins
pubmed
37507029
uniprot
proteins
pubmed
8601400
uniprot
proteins
pubmed
9683532
uniprot
proteins
sequence_length
336
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q62834}.
uniprot
proteins