NQO2
entrez
4835
canonical
uniprot
P16083
canonical
ensembl
ENSG00000124588
resolver
ensp
ENSP00000337773
resolver
ensp
ENSP00000369795
resolver
ensp
ENSP00000369806
resolver
ensp
ENSP00000369821
resolver
ensp
ENSP00000369822
resolver
ensp
ENSP00000562266
resolver
ensp
ENSP00000562267
resolver
ensp
ENSP00000562268
resolver
ensp
ENSP00000562269
resolver
ensp
ENSP00000562271
resolver
ensp
ENSP00000562272
resolver
ensp
ENSP00000562273
resolver
ensp
ENSP00000562274
resolver
ensp
ENSP00000562275
resolver
ensp
ENSP00000562276
resolver
ensp
ENSP00000562278
resolver
ensp
ENSP00000562279
resolver
ensp
ENSP00000562280
resolver
ensp
ENSP00000562281
resolver
ensp
ENSP00000562282
resolver
ensp
ENSP00000562283
resolver
ensp
ENSP00000562284
resolver
ensp
ENSP00000562285
resolver
ensp
ENSP00000562286
resolver
ensp
ENSP00000562287
resolver
ensp
ENSP00000562288
resolver
ensp
ENSP00000562289
resolver
ensp
ENSP00000562290
resolver
ensp
ENSP00000562291
resolver
ensp
ENSP00000562292
resolver
ensp
ENSP00000562293
resolver
ensp
ENSP00000562294
resolver
ensp
ENSP00000562295
resolver
ensp
ENSP00000562297
resolver
ensp
ENSP00000562298
resolver
ensp
ENSP00000562299
resolver
ensp
ENSP00000599264
resolver
ensp
ENSP00000599267
resolver
ensp
ENSP00000599271
resolver
ensp
ENSP00000599272
resolver
ensp
ENSP00000599273
resolver
ensp
ENSP00000599275
resolver
ensp
ENSP00000599276
resolver
ensp
ENSP00000599277
resolver
ensp
ENSP00000599283
resolver
ensp
ENSP00000599286
resolver
ensp
ENSP00000599287
resolver
ensp
ENSP00000599288
resolver
ensp
ENSP00000622496
resolver
ensp
ENSP00000622497
resolver
ensp
ENSP00000622498
resolver
ensp
ENSP00000622499
resolver
ensp
ENSP00000622500
resolver
ensp
ENSP00000622501
resolver
ensp
ENSP00000622502
resolver
ensp
ENSP00000622503
resolver
ensp
ENSP00000622504
resolver
ensp
ENSP00000622505
resolver
ensp
ENSP00000622506
resolver
ensp
ENSP00000622507
resolver
ensp
ENSP00000622508
resolver
ensp
ENSP00000622509
resolver
ensp
ENSP00000622510
resolver
ensp
ENSP00000622512
resolver
ensp
ENSP00000622513
resolver
ensp
ENSP00000622514
resolver
ensp
ENSP00000622515
resolver
ensp
ENSP00000622516
resolver
enst
ENST00000338130
resolver
enst
ENST00000380430
resolver
enst
ENST00000380441
resolver
enst
ENST00000380454
resolver
enst
ENST00000380455
resolver
enst
ENST00000892207
resolver
enst
ENST00000892208
resolver
enst
ENST00000892209
resolver
enst
ENST00000892210
resolver
enst
ENST00000892212
resolver
enst
ENST00000892213
resolver
enst
ENST00000892214
resolver
enst
ENST00000892215
resolver
enst
ENST00000892216
resolver
enst
ENST00000892217
resolver
enst
ENST00000892219
resolver
enst
ENST00000892220
resolver
enst
ENST00000892221
resolver
enst
ENST00000892222
resolver
enst
ENST00000892223
resolver
enst
ENST00000892224
resolver
enst
ENST00000892225
resolver
enst
ENST00000892226
resolver
enst
ENST00000892227
resolver
enst
ENST00000892228
resolver
enst
ENST00000892229
resolver
enst
ENST00000892230
resolver
enst
ENST00000892231
resolver
enst
ENST00000892232
resolver
enst
ENST00000892233
resolver
enst
ENST00000892234
resolver
enst
ENST00000892235
resolver
enst
ENST00000892236
resolver
enst
ENST00000892238
resolver
enst
ENST00000892239
resolver
enst
ENST00000892240
resolver
enst
ENST00000929205
resolver
enst
ENST00000929208
resolver
enst
ENST00000929212
resolver
enst
ENST00000929213
resolver
enst
ENST00000929214
resolver
enst
ENST00000929216
resolver
enst
ENST00000929217
resolver
enst
ENST00000929218
resolver
enst
ENST00000929224
resolver
enst
ENST00000929227
resolver
enst
ENST00000929228
resolver
enst
ENST00000929229
resolver
enst
ENST00000952437
resolver
enst
ENST00000952438
resolver
enst
ENST00000952439
resolver
enst
ENST00000952440
resolver
enst
ENST00000952441
resolver
enst
ENST00000952442
resolver
enst
ENST00000952443
resolver
enst
ENST00000952444
resolver
enst
ENST00000952445
resolver
enst
ENST00000952446
resolver
enst
ENST00000952447
resolver
enst
ENST00000952448
resolver
enst
ENST00000952449
resolver
enst
ENST00000952450
resolver
enst
ENST00000952451
resolver
enst
ENST00000952453
resolver
enst
ENST00000952454
resolver
enst
ENST00000952455
resolver
enst
ENST00000952456
resolver
enst
ENST00000952457
resolver
genesymbol
NQO2
resolver
genesymbol_syn
NMOR2
resolver
hgnc
HGNC:7856
resolver
uniprot
B2R492
resolver
uniprot
B3KPX6
resolver
uniprot
Q5TD04
resolver
uniprot
Q5TD07
resolver
uniprot_entry
B3KPX6_HUMAN
resolver
uniprot_entry
NQO2_HUMAN
resolver
uniprot_entry
Q5TD07_HUMAN
resolver
uniprot_sec
B2R492
resolver
uniprot_sec
Q5TD04
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by melatonin, resveratrol and 5-hydroxytryptamine. {ECO:0000269|PubMed:18254726}.
uniprot
proteins
amino_acid_sequence
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
uniprot
proteins
ec_number
1.10.5.1
uniprot
proteins
function
FUNCTION: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. {ECO:0000269|PubMed:18254726}.
uniprot
proteins
mass_dalton
25919
uniprot
proteins
mutagenesis
MUTAGEN 162; /note="N->H: Loss of activity toward CB1954, no effect toward menadione."; /evidence="ECO:0000269|PubMed:16129418
uniprot
proteins
protein_family
NAD(P)H dehydrogenase (quinone) family
uniprot
proteins
pubmed
10433694
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15078100
uniprot
proteins
pubmed
15350128
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16129418
uniprot
proteins
pubmed
1691923
uniprot
proteins
pubmed
18254726
uniprot
proteins
pubmed
18579530
uniprot
proteins
pubmed
19236722
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8182056
uniprot
proteins
pubmed
9050836
uniprot
proteins
pubmed
9367528
uniprot
proteins
sequence_length
231
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins