CALCB
entrez
797
canonical
uniprot
P10092
canonical
ensembl
ENSG00000175868
resolver
ensp
ENSP00000346017
resolver
ensp
ENSP00000433490
resolver
ensp
ENSP00000557866
resolver
ensp
ENSP00000557867
resolver
ensp
ENSP00000588298
resolver
ensp
ENSP00000588299
resolver
ensp
ENSP00000588300
resolver
ensp
ENSP00000588301
resolver
enst
ENST00000324229
resolver
enst
ENST00000533448
resolver
enst
ENST00000887807
resolver
enst
ENST00000887808
resolver
enst
ENST00000918239
resolver
enst
ENST00000918240
resolver
enst
ENST00000918241
resolver
enst
ENST00000918242
resolver
genesymbol
CALCB
resolver
genesymbol_syn
CALC2
resolver
hgnc
HGNC:1438
resolver
uniprot
A8K573
resolver
uniprot
D3DQX4
resolver
uniprot
Q569I0
resolver
uniprot
Q9UCN9
resolver
uniprot_entry
CALCB_HUMAN
resolver
uniprot_sec
A8K573
resolver
uniprot_sec
D3DQX4
resolver
uniprot_sec
Q569I0
resolver
uniprot_sec
Q9UCN9
resolver
amino_acid_sequence
MGFRKFSPFLALSILVLYQAGSLQAAPFRSALESSPDPATLSKEDARLLLAALVQDYVQMKASELKQEQETQGSSSAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAFGRRRRDLQA
uniprot
proteins
function
FUNCTION: CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (PubMed:3492492). {ECO:0000269|PubMed:1318039, ECO:0000269|PubMed:3492492, ECO:0000269|PubMed:9620797}.
uniprot
proteins
mass_dalton
13706
uniprot
proteins
protein_family
Calcitonin family
uniprot
proteins
pubmed
1318039
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2322288
uniprot
proteins
pubmed
2985435
uniprot
proteins
pubmed
3492393
uniprot
proteins
pubmed
3492492
uniprot
proteins
pubmed
9620797
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1318039}.
uniprot
proteins