Mpzl1
entrez
360871
canonical
uniprot
Q6AYT8
canonical
ensembl
ENSRNOG00000003248
resolver
ensembl
ENSRNOG00055017618
resolver
ensembl
ENSRNOG00060009734
resolver
ensembl
ENSRNOG00065019725
resolver
ensp
ENSRNOP00000004376
resolver
ensp
ENSRNOP00000089948
resolver
ensp
ENSRNOP00055023953
resolver
ensp
ENSRNOP00060012873
resolver
ensp
ENSRNOP00065026639
resolver
enst
ENSRNOT00000004376
resolver
enst
ENSRNOT00000093821
resolver
enst
ENSRNOT00055029821
resolver
enst
ENSRNOT00060016465
resolver
enst
ENSRNOT00065033282
resolver
genesymbol
Mpzl1
resolver
uniprot
A0A8I6A952
resolver
uniprot_entry
A0A8I6A952_RAT
resolver
uniprot_entry
MPZL1_RAT
resolver
amino_acid_sequence
MAEAVGAVTLIAAPARRRWLWSALAAMLGLLTARISALEVHTPKEIFVVNGTQGKLTCTFDSPNTTGWLTTVSWSFQPEGTDSAVSFFHYSQGQVYIGDYPPFKDRVTWAGDLDKKDASINIENIQAVHNGTYICDVKNPPDIVVRPGQIRLHVVEIDNLLVFLVWVVVGTVTAVVLGLTLLISLVLVVLYRRKHSKRDYTGCSTSERLSPVKQAPRKCPSDTEGLVKSPPSAGSHQGPVIYAQLDHSGGHHSGKINKSESVVYADIRKD
uniprot
proteins
function
FUNCTION: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. May be involved in regulation of integrin-mediated cell motility (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
29502
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues upon stimulation with pervanadate and concanavalin-A (ConA). Phosphorylation at Tyr-242 and Tyr-264 is required for interaction with PTPN11/SHP-2. Dephosphorylated by PTPN11/SHP-2 (in vitro) (By similarity). {ECO:0000250}.; PTM: N-glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
Myelin P0 protein family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
270
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 163..183; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins