Chst9
entrez
71367
canonical
uniprot
Q76EC5
canonical
ensembl
ENSMUSG00000047161
resolver
ensp
ENSMUSP00000049975
resolver
enst
ENSMUST00000053017
resolver
genesymbol
Chst9
resolver
uniprot_entry
CHST9_MOUSE
resolver
amino_acid_sequence
MKAKQVFFSVLLFGTAGLLLFMYLQAWIEEHHTGKIEKKRDQKGVSVTTGKIQKQITNQNSEVHMPEDLKKKGGDLLNLGSPTRVLRKISHSQRENGAYRSTEAHQGAKIEVFQKPIQMDWPLVTQPLNKSLVQGNKWKKADATQEKRRSFLHEFCKKYGRVNDPKFNLFHIVSRIYVEDKHKILYCEVPKAGCSNWKRILMVLNGLASSAYNISHDTVHYGKHLKTLDSFDLKGVHMRLNTYTKAVFVRDPMERLVSAFRDKFEHPNSYYHPVFGKAIIKKYRPNASAEALNNGSGVKFKEFAYYLLDAHRPVGMDIHWERVSKLCYPCLINYDFVGKFETLGEDANYFLQLIGAPKELTFPNFKDRHSSDERTNAHVVRQYLKDLSTAERQLIYDFYHLDYLMFNYTTPHL
uniprot
proteins
ec_number
2.8.2.-
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of sulfate from 3'-phosphoadenylyl sulfate (PAPS) to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans (PubMed:12944377). Transfers sulfate to the C-4 hydroxyl of terminal beta-1,4-linked GalNAc in the sequence GalNAc-beta-1,4GlcNAcbeta-R found on N-linked oligosaccharides and to the nonterminal beta-1,4-linked GalNAc in chondroitin and dermatan. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures (By similarity). {ECO:0000250|UniProtKB:Q7L1S5, ECO:0000269|PubMed:12944377}.
uniprot
proteins
mass_dalton
48004
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; carbohydrate sulfation. {ECO:0000250|UniProtKB:Q7L1S5}.
uniprot
proteins
protein_family
Sulfotransferase 2 family
uniprot
proteins
pubmed
12944377
uniprot
proteins
sequence_length
413
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 6..26; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins