Defb22
entrez
442835
canonical
uniprot
Q8BVC1
canonical
ensembl
ENSMUSG00000027468
resolver
ensp
ENSMUSP00000028966
resolver
enst
ENSMUST00000028966
resolver
genesymbol
Defb22
resolver
uniprot_entry
DFB22_MOUSE
resolver
amino_acid_sequence
MKSLLSTLVIIMFLAHLVTGGWYVKKCANTLGNCRKMCRDGEKQTEPATSKCPIGKLCCVLDFKISGHCGGGGQNSDNLVTAGGDEGSSAKASTAAMVGAAAMAGTPTKTSAPAKTSAPAKTSTTTKASNAAKASTTTKASNAAKASAATMAGNTTKVSTAAIASTPAQASTPTKANST
uniprot
proteins
function
FUNCTION: Probable component of sperm glycocalyx. Likely protects and facilitates transport of sperm in the female reproductive tract. Probably released from the sperm surface during capacitation. {ECO:0000269|PubMed:18787081}.
uniprot
proteins
mass_dalton
17709
uniprot
proteins
post_translational_modification
PTM: O-glycosylated; glycans contain alpha(2,3)-linked sialic acids. {ECO:0000250|UniProtKB:Q9BYW3}.
uniprot
proteins
protein_family
Beta-defensin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16033865
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18787081
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
179
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:18787081}. Secreted, extracellular space {ECO:0000269|PubMed:18787081}. Note=In the corpus epididymis, located in vesicles below the apical surface of the plasma membrane. Secreted by epididymal cells and absorbed to the surface of sperm during transit through the epididymis. Coats the entire surface of ejaculated sperm although presence on the equatorial segment is less intense. {ECO:0000269|PubMed:18787081}.
uniprot
proteins