Coq8b
entrez
308453
canonical
uniprot
Q6AY19
canonical
ensembl
ENSRNOG00000020848
resolver
ensembl
ENSRNOG00055033572
resolver
ensembl
ENSRNOG00060032549
resolver
ensembl
ENSRNOG00065033763
resolver
ensp
ENSRNOP00000028290
resolver
ensp
ENSRNOP00055047871
resolver
ensp
ENSRNOP00060046598
resolver
ensp
ENSRNOP00065047734
resolver
enst
ENSRNOT00000028290
resolver
enst
ENSRNOT00055058031
resolver
enst
ENSRNOT00060056396
resolver
enst
ENSRNOT00065057985
resolver
genesymbol
Coq8b
resolver
genesymbol_syn
Adck4
resolver
uniprot_entry
COQ8B_RAT
resolver
amino_acid_sequence
MWLELGAMLRTTCGPLGRAVRLPCAGALRLRPHWWGPCRDCLAQRVHQDQPGRGLTEDEIRRAREARLRKAPRPQLSDRSRERKVPASRISRLASFGGLAVGLGLGALAEVTKKSLPGGSLQHEGSSPFLTEANAERIVQTLCTVRGAALKIGQMLSIQDNSLISPQLQRVFERVRQSADFMPRWQMMKVLEEELGKDWQDKVASLEEVPFAAASIGQVHQGVLKDGTEVAVKIQYPGVAESIQSDVQNLLALLKMSVGLPEGLFAEQSLQTLQQELAWECDYRREAACAQTFKKLLADDPFFRVPAVVEELCTTRVLGMELAGGIPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHKVTLLDFGASRAFGTEFTDHYIEVVKAAADGDRDRVLQKSQDLKFLTGFETKAFSDAHVEAVMILGEPFAASGSYDFGAGETARRIQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLHAHIACRDLFQDTYHRYWASRQTLPLPAAS
uniprot
proteins
ec_number
2.7.-.-
uniprot
proteins
function
FUNCTION: Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is still unclear: may act as a protein kinase that mediates phosphorylation of COQ3 (By similarity). According to other reports, acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity). However, the small molecule kinase activity was not confirmed by another publication. Required for podocyte migration (By similarity). {ECO:0000250|UniProtKB:Q8NI60, ECO:0000250|UniProtKB:Q96D53}.
uniprot
proteins
mass_dalton
58905
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000250|UniProtKB:Q96D53}.
uniprot
proteins
protein_family
ADCK protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24270420
uniprot
proteins
sequence_length
528
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:Q96D53}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q96D53}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q96D53}. Cell membrane {ECO:0000250|UniProtKB:Q96D53}.
uniprot
proteins
transmembrane_region
TRANSMEM 93..109; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins