Timp2
entrez
29543
canonical
uniprot
P30121
canonical
ensembl
ENSRNOG00000089169
resolver
ensembl
ENSRNOG00055031858
resolver
ensembl
ENSRNOG00060030518
resolver
ensembl
ENSRNOG00065004980
resolver
ensp
ENSRNOP00000004290
resolver
ensp
ENSRNOP00000111326
resolver
ensp
ENSRNOP00055045611
resolver
ensp
ENSRNOP00060044112
resolver
ensp
ENSRNOP00065005067
resolver
enst
ENSRNOT00000004290
resolver
enst
ENSRNOT00000123373
resolver
enst
ENSRNOT00055055187
resolver
enst
ENSRNOT00060053062
resolver
enst
ENSRNOT00065007292
resolver
genesymbol
Timp2
resolver
genesymbol_syn
Timp-2
resolver
uniprot
A0ABK0M2Y4
resolver
uniprot
Q546J4
resolver
uniprot_entry
A0ABK0M2Y4_RAT
resolver
uniprot_entry
TIMP2_RAT
resolver
uniprot_sec
Q546J4
resolver
amino_acid_sequence
MGAAARSLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPDKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSITQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
uniprot
proteins
function
FUNCTION: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
uniprot
proteins
mass_dalton
24356
uniprot
proteins
post_translational_modification
PTM: The activity of TIMP2 is dependent on the presence of disulfide bonds.
uniprot
proteins
protein_family
Protease inhibitor I35 (TIMP) family
uniprot
proteins
pubmed
11684074
uniprot
proteins
pubmed
1309971
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8050496
uniprot
proteins
pubmed
8203893
uniprot
proteins
pubmed
8792217
uniprot
proteins
sequence_length
220
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins