Q9QXG2
uniprot
Q9QXG2
canonical
amino_acid_sequence
MADNLPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFSFSGLLSWLKEYQENSDVVTENSMWQEQILENEEAILLSSKDKTIQHVEVFCYASQDLHKDVEEAGALQKNPASVMSAQATEAAEAAEAAEATEAAEAAEAAEAACLPTAEESLSTRSCELPAEQSQCMGPESSPQVNDAEVGEKETQSDAKSSTEQSSEILPKVQDNTETPKRNVITYSQIIKEGRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGTVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCVEYEDHPDEYKAYEETTFSEYLKTQKLTPNLQYFVLHSIAMTSETTSSTVDGLKATKKFLQCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAIVDQFGQRIISKHFVIEDSYLSENTCSGVQYRQISRAVLITDGSVLKPDSDQQVSILTVPAEESGSFAVRVIELCSSTMTCMKGTYLVHLTCMSSKTAREDLERVVQKLFTPYTEIEAENEQVEKPRILWALYFNMRDSSDISRDCYNDLPSNVYVCSGPDCNLGNDNAVQQAEIVFQKICPNEDFCPAPPNPEDIILDGDSSQQEVSESSVIPETNSETPKESTVLGDSEEPSE
uniprot
proteins
function
FUNCTION: Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
73977
uniprot
proteins
protein_family
Rab GDI family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
665
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}.
uniprot
proteins