Sgf29
entrez
293488
canonical
uniprot
P0C606
canonical
ensembl
ENSRNOG00000019245
resolver
ensp
ENSRNOP00000105175
resolver
ensp
ENSRNOP00000110557
resolver
enst
ENSRNOT00000135316
resolver
enst
ENSRNOT00000151185
resolver
genesymbol
Sgf29
resolver
genesymbol_syn
Ccdc101
resolver
uniprot
A0ABK0M7W0
resolver
uniprot_entry
A0ABK0M7W0_RAT
resolver
uniprot_entry
SGF29_RAT
resolver
amino_acid_sequence
MALVSADSRIAELLTELHQLIKQTQEERSRSEHNLVNIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGLYNDSEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVAKPGDKVAARVKAVEGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRIIPLPQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHTPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKEPKKK
uniprot
proteins
function
FUNCTION: Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes (By similarity). SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) (By similarity). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me (By similarity). Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival (By similarity). Also binds non-histone proteins that are methylated on Lys residues: specifically recognizes and binds CGAS monomethylated on 'Lys-491' (By similarity). May be involved in MYC-mediated oncogenic transformation (PubMed:17334388). {ECO:0000250|UniProtKB:Q96ES7, ECO:0000250|UniProtKB:Q9DA08, ECO:0000269|PubMed:17334388}.
uniprot
proteins
mass_dalton
33268
uniprot
proteins
protein_family
SGF29 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
17334388
uniprot
proteins
sequence_length
293
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17334388}.
uniprot
proteins