KLF2
entrez
10365
canonical
uniprot
Q9Y5W3
canonical
ensembl
ENSG00000127528
resolver
ensp
ENSP00000248071
resolver
enst
ENST00000248071
resolver
genesymbol
KLF2
resolver
genesymbol_syn
LKLF
resolver
hgnc
HGNC:6347
resolver
uniprot
Q6IPC4
resolver
uniprot
Q9UJS5
resolver
uniprot
Q9UKR6
resolver
uniprot_entry
KLF2_HUMAN
resolver
uniprot_sec
Q6IPC4
resolver
uniprot_sec
Q9UJS5
resolver
uniprot_sec
Q9UKR6
resolver
amino_acid_sequence
MALSEPILPSFSTFASPCRERGLQERWPRAEPESGGTDDDLNSVLDFILSMGLDGLGAEAAPEPPPPPPPPAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPLGPALHGRFLLAPPGRLVKAEPPEADGGGGYGCAPGLTRGPRGLKREGAPGPAASCMRGPGGRPPPPPDTPPLSPDGPARLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAPPAFGLFDDAAAAAAALGLAPPAARGLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM
uniprot
proteins
function
FUNCTION: Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription (PubMed:21063504). Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements (PubMed:28167758). {ECO:0000269|PubMed:21063504, ECO:0000269|PubMed:28167758}.
uniprot
proteins
mass_dalton
37420
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Krueppel C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
10217429
uniprot
proteins
pubmed
10458913
uniprot
proteins
pubmed
11375995
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21063504
uniprot
proteins
pubmed
28167758
uniprot
proteins
pubmed
31375868
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins