Aoc2
entrez
237940
canonical
uniprot
Q812C9
canonical
ensembl
ENSMUSG00000078651
resolver
ensp
ENSMUSP00000040255
resolver
enst
ENSMUST00000041095
resolver
genesymbol
Aoc2
resolver
uniprot
A2A4J0
resolver
uniprot
Q80WP3
resolver
uniprot_entry
AOC2_MOUSE
resolver
uniprot_sec
A2A4J0
resolver
uniprot_sec
Q80WP3
resolver
amino_acid_sequence
MNLKVLLLLLGLSFLTVFALVYVLLTRQGSFSQSPRCPSIPPRIHPWTHPSQSQLFADLTPEELTAVMSFLTKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHGGPLPYYRRPMQKTEFVQIWRHLKEVELPKAPTFLASVLNYNGSTLAPLHSTASGFHAGDRATWIALYHNISGLGVFLHPVGLELLLDHGALDPADWVVQQVFYLGHYYADLAQLEWEFKVGRLEVIRVPLPTPGGASSLRPRVTPDPPLPPLQFSLQGPQYNIQGNSVTSPLWTFTFGHGVFSGLRIFDIRFKGERVAYEVSVQECLTVYGADSPKTMTIRYLDSSYGLGLNSRALVRGVDCPYQATMVDIHVLVGTGSVQLLPGAVCVFEEAQGLPLRRHHNGIGGHFYGGLASSSLVVRSVSSVGNYDYIWDFMLHPTGALEARVHATGYINTAFMSGGAESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVIAEDAVFKPVAAPWNPELQLQRPQLTRQVLSREDLAAFPWGSPLPRYLYLATNQTNAWGHQRGYRIQIHSPPGVHVPLESSEERALSWGRYQLVVTQRKEAEPHSSSIYYQNDMRSPATVFADFINNETLLGEDLVAWVTASFLHIPHAEDIPNTVTVGNRVGFLLRPYNFFNEDPSIFSPGSVYFERDQDAGLCSINPVACTQQLADCVPNLPSFSYEGL
uniprot
proteins
ec_number
1.4.3.21
uniprot
proteins
function
FUNCTION: Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for 2-phenylethylamine, tryptamine and tyramine. Could also act on methylamine and benzylamine but much less efficiently. {ECO:0000250|UniProtKB:O75106}.
uniprot
proteins
mass_dalton
83583
uniprot
proteins
post_translational_modification
PTM: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. {ECO:0000250|UniProtKB:Q16853}.
uniprot
proteins
protein_family
Copper/topaquinone oxidase family
uniprot
proteins
pubmed
14585497
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
757
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O75106}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q16853}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..25; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins