Astn1
entrez
11899
canonical
uniprot
Q61137
canonical
ensembl
ENSMUSG00000026587
resolver
ensp
ENSMUSP00000039711
resolver
ensp
ENSMUSP00000127428
resolver
ensp
ENSMUSP00000141518
resolver
ensp
ENSMUSP00000142322
resolver
ensp
ENSMUSP00000240428
resolver
ensp
ENSMUSP00000240433
resolver
enst
ENSMUST00000170718
resolver
genesymbol
Astn1
resolver
genesymbol_syn
Astn
resolver
genesymbol_syn
Kiaa0289
resolver
uniprot
F6TTD5
resolver
uniprot
G5E8A1
resolver
uniprot
Q3TPU9
resolver
uniprot
Q3UHD7
resolver
uniprot
Q505A0
resolver
uniprot
Q7TQG3
resolver
uniprot
Q8CHH2
resolver
uniprot_entry
ASTN1_MOUSE
resolver
uniprot_entry
F6TTD5_MOUSE
resolver
uniprot_entry
Q3TPU9_MOUSE
resolver
uniprot_entry
Q3UHD7_MOUSE
resolver
uniprot_sec
G5E8A1
resolver
uniprot_sec
Q505A0
resolver
uniprot_sec
Q7TQG3
resolver
uniprot_sec
Q8CHH2
resolver
amino_acid_sequence
MALAGLCALFACCWGPAAVLATAAGDVDPSKELECKLKSITVSALPFLRENDLSIMHSPSASEPKLLFSVRNDFPGEMVVVDDLENTELPYFVLEISGNTEDIPLVRWRQQWLENGTLLFHIHHQDGAPSLPGQDPTEEPQHESAEEELRILHISVMGGMIALLLSILCLVMILYTRRRWCKRRRVPQPQKSASAEAANEIHYIPSVLIGGHGRESLRNARVQGHNSSGTLSIRETPILDGYEYDITDLRHHLQRECMNGGEDFASQVTRTLDSLQGCNEKSGMDLTPGSDNAKLSLMNKYKDNIIATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSSTEAENDPQLTFYTDPSRSRRRSRVGSPRSPVNKTTLTLISVTSCVIGLVCSSHVSCPLVVKITLHVPEHLIADGSRFILLEGSQLDASDWLNPAQVVLFSQQNSSGPWAMDLCARRLLDPCEHQCDPETGRREHRAAGECLCYEGYMKDPVHKHLCIRNEWGTNQGPWPYTIFQRGFDLVLGEQPSDKIFRFTYTLGEGMWLPLSKSFVIPPAELAINPSAKCKTDMTVMEDAVEVREELMTSSSFDSLEVLLDSFGPVRDCSKDNGGCSKNFRCISDRKLDSTGCVCPSGLSPMKDSSGCYDRHIGVDCSDGFNGGCEQLCLQQMAPFPEDPTLYNILMFCGCIEDYKLGVDGRSCQLVTETCPEGGDCGESREVPMNQTLFGEMFFGYNNQSKEVATGQVLKGTFRQNNFARGLDQQLPDGLVVASVPLENQCLEEISEPTPDPDFLTGMVNFSEVSGYPVLQHWKVRSVMYHIKLNQAAISQAFSNALHSLDGATSRADFVALLDQFGNHYIQEAVYGFEESCSIWYPNKQVQRRLWLEYEDISKGNSPSDESEERERDPKVLTFPEYIASLSDSGTKRMAAGVRMECQSKGRCPSSCPLCHVTSSPETPAEPVLLEVTRASPIYELVTNNQTQRLLQEATMSSLWCSGTGDVIEDWCRCDSTAFGADGLPTCAPLPQPVLRLSTVHEPSSNLVVLEWEHSEPPIGVQIVDYLIRQEKVTDRMDHSKVETETVLSFVDDIISGAKAPCAMPSQVPDKQLTTISLIIRCLEPDTIYMFTLWGVDNTGRRSRPSDVIVKTPCPVVDDVKAQEIADKIYNLFNGYTSGKEQQTAYNTLLDLGSPTLHRVLYHYNQHYESFGEFTWRCEDELGPRKAGLILSQLGDLSSWCNGLLQEPKISLRRGSLKYLGCRYSEIKPYGLDWSELSRDLRKTCEEQTLSVPYNDYGDSKDI
uniprot
proteins
function
FUNCTION: Neuronal adhesion molecule that is required for normal migration of young postmitotic neuroblasts along glial fibers, especially in the cerebellum. Required for normal rate of migration of granule cells during brain development and for normal cerebellum development. {ECO:0000269|PubMed:11861479, ECO:0000269|PubMed:8602532}.
uniprot
proteins
mass_dalton
144884
uniprot
proteins
protein_family
Astrotactin family
uniprot
proteins
pubmed
11861479
uniprot
proteins
pubmed
12465718
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20573900
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
8602532
uniprot
proteins
sequence_length
1302
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20573900, ECO:0000269|PubMed:8602532}; Multi-pass membrane protein {ECO:0000305}. Perikaryon {ECO:0000269|PubMed:20573900}. Endosome {ECO:0000269|PubMed:20573900}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000305|PubMed:20573900}. Note=Detected close to the anterior pole and at the base of the leading process in migrating neurons. Is internalized from the membrane via clathrin-coated vesicles and endosomes, and recycled to the anterior pole of the migrating cell. {ECO:0000269|PubMed:20573900}.
uniprot
proteins
transmembrane_region
TRANSMEM 154..174; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 389..409; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins