C15orf39
entrez
56905
canonical
uniprot
Q6ZRI6
canonical
ensembl
ENSG00000167173
resolver
ensp
ENSP00000353854
resolver
ensp
ENSP00000378438
resolver
genesymbol
C15orf39
resolver
hgnc
HGNC:24497
resolver
uniprot
B3KWI3
resolver
uniprot
C9J888
resolver
uniprot
Q71JB1
resolver
uniprot
Q7L3S0
resolver
uniprot
Q8N3F2
resolver
uniprot
Q96FB6
resolver
uniprot
Q9NTU5
resolver
uniprot_entry
CO039_HUMAN
resolver
uniprot_sec
B3KWI3
resolver
uniprot_sec
C9J888
resolver
uniprot_sec
Q71JB1
resolver
uniprot_sec
Q7L3S0
resolver
uniprot_sec
Q8N3F2
resolver
uniprot_sec
Q96FB6
resolver
uniprot_sec
Q9NTU5
resolver
amino_acid_sequence
MAEKRPLRTLGPVMYGKLPRLETDSGLEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAESEQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEGARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAGAIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTTLSEERALRELALPGCTSRMLKLLALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSSEPTVARGEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPPGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSPCPQLLDSQSHHL
uniprot
proteins
function
FUNCTION: Negatively regulates microglial inflammatory responses (PubMed:38892217). Inhibits NF-kappa-B signaling by interacting with PRMT2, thereby reducing the production of pro-inflammatory cytokines, maintaining a steady-state in microglia and limiting excessive inflammation (PubMed:38892217). {ECO:0000269|PubMed:38892217}.
uniprot
proteins
mass_dalton
110673
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15498874
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
38892217
uniprot
proteins
sequence_length
1047
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:38892217}. Nucleus {ECO:0000269|PubMed:38892217}.
uniprot
proteins