CENPH
entrez
64946
canonical
uniprot
Q9H3R5
canonical
ensembl
ENSG00000153044
resolver
ensp
ENSP00000283006
resolver
enst
ENST00000283006
resolver
genesymbol
CENPH
resolver
genesymbol_syn
ICEN35
resolver
hgnc
HGNC:17268
resolver
uniprot
A0A0S2Z5T0
resolver
uniprot
A8K3Y1
resolver
uniprot_entry
A0A0S2Z5T0_HUMAN
resolver
uniprot_entry
CENPH_HUMAN
resolver
uniprot_sec
A8K3Y1
resolver
amino_acid_sequence
MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQTKQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKKLALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDLEEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQLEKNVDMM
uniprot
proteins
function
FUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate. {ECO:0000269|PubMed:14536089, ECO:0000269|PubMed:16875666, ECO:0000269|PubMed:18007590}.
uniprot
proteins
mass_dalton
28481
uniprot
proteins
protein_family
CENP-H/MCM16 family
uniprot
proteins
pubmed
11092768
uniprot
proteins
pubmed
14536089
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15713649
uniprot
proteins
pubmed
16622419
uniprot
proteins
pubmed
16622420
uniprot
proteins
pubmed
16716197
uniprot
proteins
pubmed
16875666
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17651496
uniprot
proteins
pubmed
18007590
uniprot
proteins
pubmed
19381461
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
247
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Chromosome, centromere, kinetochore. Note=Associates with active centromere-kinetochore complexes throughout the cell cycle. Colocalizes with inner kinetochore plate proteins CENPA and CENPC during both interphase and metaphase.
uniprot
proteins