Klhdc8b
entrez
306589
canonical
uniprot
Q5XIA9
canonical
ensembl
ENSRNOG00000047867
resolver
ensembl
ENSRNOG00055013515
resolver
ensembl
ENSRNOG00060025740
resolver
ensembl
ENSRNOG00065006652
resolver
ensp
ENSRNOP00000095128
resolver
ensp
ENSRNOP00055018807
resolver
ensp
ENSRNOP00060036893
resolver
ensp
ENSRNOP00065007514
resolver
enst
ENSRNOT00000101706
resolver
enst
ENSRNOT00055023169
resolver
enst
ENSRNOT00060044532
resolver
enst
ENSRNOT00065010282
resolver
genesymbol
Klhdc8b
resolver
uniprot_entry
KLD8B_RAT
resolver
amino_acid_sequence
MAAGGGQAFAWQVFPPMPTCRVYGTVAHQDGHLLVLGGCGRAGLPLDTAETLDMASHTWLALAPLPTARAGAAAVVLGKQVLVVGGVDEVQSPVAAVEAFLADEGRWERRATLPQAAMGVATVERDGMVYALGGMGPDTAPQAQVLVYESRRDRWLSLPSMPTPCYGASTFLHGNKIYVLGGRQGKLPVTAFEAFDLETRTWTRHPSLPSRRAFAGCAMAEGSVFSLGGLQQPGPHNFYSRPHFVNTVEMFDLEHGSWTKLPRSLRMRDKRADFVVGSLGGNIVAIGGLGNQPCPLASVESFSLARRRWEALPAMPTARCSCSSLQAGPRLFVIGGVAQGPSQAVEALCLRDGV
uniprot
proteins
function
FUNCTION: Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis. Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells. {ECO:0000250|UniProtKB:Q8IXV7}.
uniprot
proteins
mass_dalton
37593
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
354
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8IXV7}. Midbody {ECO:0000250|UniProtKB:Q8IXV7}. Note=In mitotic cells, concentrates in the midbody of the cytoplasmic bridge linking daughter cells as they are about to separate during cytokinesis. {ECO:0000250|UniProtKB:Q8IXV7}.
uniprot
proteins