TRIM47
entrez
91107
canonical
uniprot
Q96LD4
canonical
ensembl
ENSG00000132481
resolver
ensp
ENSP00000254816
resolver
genesymbol
TRIM47
resolver
genesymbol_syn
GOA
resolver
genesymbol_syn
RNF100
resolver
hgnc
HGNC:19020
resolver
uniprot
Q96AD0
resolver
uniprot
Q96GU5
resolver
uniprot
Q9BRN7
resolver
uniprot_entry
TRI47_HUMAN
resolver
uniprot_sec
Q96AD0
resolver
uniprot_sec
Q96GU5
resolver
uniprot_sec
Q9BRN7
resolver
amino_acid_sequence
MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD (PubMed:29291351). It also mediates the ubiquitination and proteasomal degradation of ADAM17 (PubMed:38771644). {ECO:0000269|PubMed:29291351, ECO:0000269|PubMed:38771644}.
uniprot
proteins
mass_dalton
69532
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:29291351}.
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
11511098
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
29291351
uniprot
proteins
pubmed
38771644
uniprot
proteins
sequence_length
638
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11511098}. Nucleus {ECO:0000269|PubMed:11511098}.
uniprot
proteins