EXOC6
entrez
54536
canonical
uniprot
Q8TAG9
canonical
ensembl
ENSG00000138190
resolver
ensp
ENSP00000260762
resolver
ensp
ENSP00000360607
resolver
ensp
ENSP00000396206
resolver
ensp
ENSP00000500529
resolver
enst
ENST00000443748
resolver
genesymbol
EXOC6
resolver
genesymbol
SEC15L3
resolver
genesymbol_syn
SEC15A
resolver
genesymbol_syn
SEC15L
resolver
genesymbol_syn
SEC15L1
resolver
hgnc
HGNC:23196
resolver
uniprot
A5YP36
resolver
uniprot
B2RDH5
resolver
uniprot
B3KXY5
resolver
uniprot
B7Z6G5
resolver
uniprot
E7EW84
resolver
uniprot
E9PHI3
resolver
uniprot
Q5VXH8
resolver
uniprot
Q9NZ24
resolver
uniprot_entry
A5YP36_HUMAN
resolver
uniprot_entry
B2RDH5_HUMAN
resolver
uniprot_entry
B3KXY5_HUMAN
resolver
uniprot_entry
B7Z6G5_HUMAN
resolver
uniprot_entry
E7EW84_HUMAN
resolver
uniprot_entry
EXOC6_HUMAN
resolver
uniprot_sec
E9PHI3
resolver
uniprot_sec
Q5VXH8
resolver
uniprot_sec
Q9NZ24
resolver
amino_acid_sequence
MAENSESLGTVPEHERILQEIESTDTACVGPTLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHM
uniprot
proteins
function
FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
93722
uniprot
proteins
protein_family
SEC15 family
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16213214
uniprot
proteins
pubmed
21269460
uniprot
proteins
sequence_length
804
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O54923}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54923}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54923}. Midbody, Midbody ring {ECO:0000269|PubMed:16213214}. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). {ECO:0000250|UniProtKB:O54923, ECO:0000269|PubMed:16213214}.
uniprot
proteins