Rps19bp1
entrez
66538
canonical
uniprot
Q8C6B9
canonical
ensembl
ENSMUSG00000051518
resolver
ensp
ENSMUSP00000061167
resolver
enst
ENSMUST00000052499
resolver
genesymbol
Rps19bp1
resolver
genesymbol_syn
Aros
resolver
uniprot
Q2WFQ7
resolver
uniprot_entry
AROS_MOUSE
resolver
uniprot_sec
Q2WFQ7
resolver
amino_acid_sequence
MSAALVRRGLELLAASEAPRAVPGQVQASGTPAKRTRRARAKASQALKLRNSAKGKAPKSALAEYQKRQCRDHLKANLKFMTSMRSTVPESVTQQILQQNQGRKACDRLVAKTKNKKKKKKKAEGTVFTEEDFQKFQREYFGS
uniprot
proteins
function
FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Acts as a chaperone that specifically mediates the integration of RPS19 in state post-A1. Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity. {ECO:0000250|UniProtKB:Q86WX3}.
uniprot
proteins
mass_dalton
15978
uniprot
proteins
post_translational_modification
PTM: Citrullinated by PADI4. {ECO:0000269|PubMed:24463520}.
uniprot
proteins
protein_family
AROS family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16289379
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24463520
uniprot
proteins
sequence_length
143
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16289379}.
uniprot
proteins