Cavin3
entrez
109042
canonical
uniprot
Q91VJ2
canonical
ensembl
ENSMUSG00000037060
resolver
ensp
ENSMUSP00000044979
resolver
enst
ENSMUST00000047040
resolver
genesymbol
Cavin3
resolver
genesymbol_syn
Prkcdbp
resolver
genesymbol_syn
Srbc
resolver
uniprot
Q8C064
resolver
uniprot
Q9CRW1
resolver
uniprot_entry
CAVN3_MOUSE
resolver
uniprot_sec
Q8C064
resolver
uniprot_sec
Q9CRW1
resolver
amino_acid_sequence
MGESALEPGPVPETPAGGPVHAVTVVTLLEKLATMLEALRERQGGLAERQGGLAGSVRRIQSGLGALSRSHDTTSNTLTQLLAKAERVGSHADAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEETEIPARAFQKVPELLGPEDQLVLGPDQPEDEVGESSEEEPVESRAQRLRRTGLQKVQSLKRALSSRKAAQPTPVKPPRVGPVRSSEGPSEGQPAAQPEMESELETALEPEPPQPTKEDPEKPVLQIESAA
uniprot
proteins
function
FUNCTION: Regulates the traffic and/or budding of caveolae (By similarity). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells (PubMed:23652019, PubMed:28285351). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface (PubMed:25588833). Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (PubMed:23079727). {ECO:0000250|UniProtKB:Q969G5, ECO:0000269|PubMed:23079727, ECO:0000269|PubMed:23652019, ECO:0000269|PubMed:25588833, ECO:0000269|PubMed:28285351}.
uniprot
proteins
mass_dalton
27853
uniprot
proteins
post_translational_modification
PTM: In vitro, phosphorylated by PRKCD. {ECO:0000269|PubMed:9054438}.
uniprot
proteins
protein_family
CAVIN family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19546242
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23079727
uniprot
proteins
pubmed
23652019
uniprot
proteins
pubmed
25588833
uniprot
proteins
pubmed
28285351
uniprot
proteins
pubmed
9054438
uniprot
proteins
sequence_length
260
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23079727}. Cytoplasm, cytosol {ECO:0000269|PubMed:19546242}. Membrane, caveola {ECO:0000269|PubMed:19546242, ECO:0000269|PubMed:25588833}. Note=Localizes in the caveolae in a caveolin-dependent manner. {ECO:0000269|PubMed:19546242, ECO:0000269|PubMed:25588833}.
uniprot
proteins