Midn
entrez
59090
canonical
uniprot
Q3TPJ7
canonical
ensembl
ENSMUSG00000035621
resolver
ensp
ENSMUSP00000046967
resolver
ensp
ENSMUSP00000097091
resolver
ensp
ENSMUSP00000197006
resolver
ensp
ENSMUSP00000197007
resolver
ensp
ENSMUSP00000325311
resolver
ensp
ENSMUSP00000325312
resolver
genesymbol
Midn
resolver
uniprot
Q3U3X5
resolver
uniprot
Q9JJJ6
resolver
uniprot_entry
MIDN_MOUSE
resolver
uniprot_sec
Q3U3X5
resolver
uniprot_sec
Q9JJJ6
resolver
amino_acid_sequence
MEPQPGGARSCRRGAPGGACELNTATESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAAARGDSSVATPVSSPCRPVSSAARVPPVSSSPSSPVSPSPVTAGSFRSHAASTTCPEQMDCSPPASSSSTSTPGSSPTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLTQLRCHAQCSPASPAPDLTPKTTSCEKLAATSSTSLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGRSDSSSSGGGGGPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA
uniprot
proteins
function
FUNCTION: Facilitates the ubiquitin-independent proteasomal degradation of stimulus-induced transcription factors such as FOSB, EGR1, NR4A1, and IRF4 to the proteasome for degradation (By similarity). Promotes also the degradation of other substrates such as CBX4 (PubMed:27326929). Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion (By similarity). {ECO:0000250|UniProtKB:D4AE48, ECO:0000250|UniProtKB:Q504T8, ECO:0000269|PubMed:27326929}.
uniprot
proteins
mass_dalton
49192
uniprot
proteins
pubmed
10974535
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
24187134
uniprot
proteins
pubmed
27326929
uniprot
proteins
sequence_length
465
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10974535, ECO:0000269|PubMed:24187134}. Cytoplasm, cytosol {ECO:0000269|PubMed:24187134}. Nucleus, nucleolus {ECO:0000269|PubMed:10974535}. Note=Detected in the nucleus and nucleolus with no expression in the cytoplasm (PubMed:10974535). However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus (PubMed:24187134). {ECO:0000269|PubMed:10974535, ECO:0000269|PubMed:24187134}.
uniprot
proteins