Man1a2
entrez
17156
canonical
uniprot
P39098
canonical
ensembl
ENSMUSG00000008763
resolver
ensp
ENSMUSP00000008907
resolver
genesymbol
Man1a2
resolver
genesymbol_syn
Man1b
resolver
uniprot
Q5SUY6
resolver
uniprot
Q5SUY7
resolver
uniprot
Q60599
resolver
uniprot
Q9CUY9
resolver
uniprot_entry
MA1A2_MOUSE
resolver
uniprot_sec
Q5SUY6
resolver
uniprot_sec
Q5SUY7
resolver
uniprot_sec
Q60599
resolver
uniprot_sec
Q9CUY9
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by both 1-deoxymannojirimycin and kifunensine. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVAQAMKTKETRVLPPVPVPQRVGVSGGDPEDMEIKKKRDKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSTNIFGSSQMGATIVDALDTLYIMGLHDEFMDGQRWIEENLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKTKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFVHLSYLTGDLTYYNKVMHIRKLLQKMERPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARRMYDDAVEAIEKHLIKKSRGGLVFIGEWKNGHLERKMGHLACFAGGMFALGADGSRKDKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKSCRVSGGFSGVKDVYAPTPVHDDVQQSFFLAETLKYLYLLFSGDDLLPLDHWVFNTEAHPLPVLRLANSTLSGNPAVR
uniprot
proteins
ec_number
3.2.1.113
uniprot
proteins
function
FUNCTION: Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
uniprot
proteins
mass_dalton
72871
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:P32906}.
uniprot
proteins
protein_family
Glycosyl hydrolase 47 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8144579
uniprot
proteins
pubmed
9143489
uniprot
proteins
sequence_length
641
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type II membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 37..57; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins