Pigx
entrez
72084
canonical
uniprot
Q99LV7
canonical
ensembl
ENSMUSG00000023791
resolver
ensp
ENSMUSP00000093819
resolver
ensp
ENSMUSP00000114854
resolver
ensp
ENSMUSP00000141122
resolver
enst
ENSMUST00000155966
resolver
enst
ENSMUST00000189013
resolver
genesymbol
Pigx
resolver
uniprot
A0A087WSN5
resolver
uniprot
F6YX19
resolver
uniprot_entry
F6YX19_MOUSE
resolver
uniprot_entry
PIGX_MOUSE
resolver
uniprot_sec
A0A087WSN5
resolver
amino_acid_sequence
MAAGAVAWLLLWAAWLVGRLAADFSDAPFSAGKGVRATCSEIILRQEFLKDGFHRDLLIKVKFGESIEDLQTCRLLIKHYIPPGLFVDPYELASLRERNLTEAVMLSESFNIEAPNYLSNESAVLIYARQDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMYCDQEFPILKCWAQSEVAAPCALKSEEICQWKSMQYKSILKNLTVQVPVGLTIHTSLVCSVTLLITILCSTLILLAVFKYGHFSL
uniprot
proteins
function
FUNCTION: Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM. {ECO:0000250|UniProtKB:Q60GF7}.
uniprot
proteins
mass_dalton
28644
uniprot
proteins
pathway_participation
PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis. {ECO:0000250|UniProtKB:Q60GF7}.
uniprot
proteins
protein_family
PIGX family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15635094
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
254
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q60GF7}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q60GF7}.
uniprot
proteins
transmembrane_region
TRANSMEM 227..247; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins