GSTA4
entrez
2941
canonical
uniprot
O15217
canonical
ensembl
ENSG00000170899
resolver
ensp
ENSP00000360002
resolver
ensp
ENSP00000557841
resolver
genesymbol
GSTA4
resolver
hgnc
HGNC:4629
resolver
uniprot
B2RD15
resolver
uniprot
Q5T7Q8
resolver
uniprot
Q6P4G1
resolver
uniprot
Q9BX18
resolver
uniprot
Q9H414
resolver
uniprot_entry
GSTA4_HUMAN
resolver
uniprot_sec
B2RD15
resolver
uniprot_sec
Q5T7Q8
resolver
uniprot_sec
Q6P4G1
resolver
uniprot_sec
Q9BX18
resolver
uniprot_sec
Q9H414
resolver
amino_acid_sequence
MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
uniprot
proteins
ec_number
2.5.1.18
uniprot
proteins
function
FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE). {ECO:0000269|PubMed:10329152, ECO:0000269|PubMed:20085333}.
uniprot
proteins
mass_dalton
25704
uniprot
proteins
mutagenesis
MUTAGEN 9; /note="Y->F: Reduces catalytic activity 70-fold."; /evidence="ECO:0000269|PubMed:20085333"; MUTAGEN 212; /note="Y->A,F,S: Strongly reduced activity towards 4-hydroxynon-2-enal and 1-chloro-2,4-dinitrobenzene."; /evidence="ECO:0000269|PubMed:10329152
uniprot
proteins
protein_family
Alpha family
uniprot
proteins
protein_family
GST superfamily
uniprot
proteins
pubmed
10329152
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
20085333
uniprot
proteins
pubmed
9461507
uniprot
proteins
pubmed
9480897
uniprot
proteins
pubmed
9587421
uniprot
proteins
pubmed
9820822
uniprot
proteins
sequence_length
222
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins