Icmt
entrez
57295
canonical
uniprot
Q9EQK7
canonical
ensembl
ENSMUSG00000039662
resolver
ensp
ENSMUSP00000043390
resolver
enst
ENSMUST00000048892
resolver
genesymbol
Icmt
resolver
uniprot
F7BSM5
resolver
uniprot
Q3U4N2
resolver
uniprot_entry
F7BSM5_MOUSE
resolver
uniprot_entry
ICMT_MOUSE
resolver
uniprot_entry
Q3U4N2_MOUSE
resolver
amino_acid_sequence
MAAARRGSAGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSATGLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL
uniprot
proteins
ec_number
2.1.1.100
uniprot
proteins
function
FUNCTION: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. {ECO:0000269|PubMed:17652517}.
uniprot
proteins
mass_dalton
31790
uniprot
proteins
protein_family
Class VI-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
Isoprenylcysteine carboxyl methyltransferase family
uniprot
proteins
pubmed
10649571
uniprot
proteins
pubmed
17652517
uniprot
proteins
sequence_length
283
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O60725}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O60725}.
uniprot
proteins
transmembrane_region
TRANSMEM 16..32; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 41..58; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 69..86; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 92..111; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..148; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 154..173; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 212..227; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 229..243; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins