DR1
entrez
1810
canonical
uniprot
Q01658
canonical
ensembl
ENSG00000117505
resolver
ensp
ENSP00000359290
resolver
ensp
ENSP00000359295
resolver
enst
ENST00000370267
resolver
enst
ENST00000370272
resolver
genesymbol
DKFZp666G145
resolver
genesymbol
DR1
resolver
genesymbol_syn
DR1
resolver
hgnc
HGNC:3017
resolver
uniprot
D3DT41
resolver
uniprot
Q658N3
resolver
uniprot_entry
NC2B_HUMAN
resolver
uniprot_entry
Q658N3_HUMAN
resolver
uniprot_sec
D3DT41
resolver
amino_acid_sequence
MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI
uniprot
proteins
function
FUNCTION: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. {ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:8670811}.
uniprot
proteins
mass_dalton
19444
uniprot
proteins
post_translational_modification
PTM: Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.
uniprot
proteins
protein_family
NC2 beta/DR1 family
uniprot
proteins
pubmed
11461703
uniprot
proteins
pubmed
1339312
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19103755
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
8670811
uniprot
proteins
pubmed
8836190
uniprot
proteins
sequence_length
176
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins