PGBD1
entrez
84547
canonical
uniprot
Q96JS3
canonical
ensembl
ENSG00000137338
resolver
ensp
ENSP00000259883
resolver
ensp
ENSP00000506997
resolver
ensp
ENSP00000588263
resolver
ensp
ENSP00000588264
resolver
ensp
ENSP00000588265
resolver
ensp
ENSP00000588266
resolver
enst
ENST00000259883
resolver
enst
ENST00000682144
resolver
enst
ENST00000918204
resolver
enst
ENST00000918205
resolver
enst
ENST00000918206
resolver
enst
ENST00000918207
resolver
genesymbol
PGBD1
resolver
hgnc
HGNC:19398
resolver
uniprot
Q53F43
resolver
uniprot
Q6NTF5
resolver
uniprot
Q8WWS4
resolver
uniprot_entry
PGBD1_HUMAN
resolver
uniprot_sec
Q53F43
resolver
uniprot_sec
Q6NTF5
resolver
uniprot_sec
Q8WWS4
resolver
amino_acid_sequence
MYEALPGPAPENEDGLVKVKEEDPTWEQVCNSQEGSSHTQEICRLRFRHFCYQEAHGPQEALAQLRELCHQWLRPEMHTKEQIMELLVLEQFLTILPKELQPCVKTYPLESGEEAVTVLENLETGSGDTGQQASVYIQGQDMHPMVAEYQGVSLECQSLQLLPGITTLKCEPPQRPQGNPQEVSGPVPHGSAHLQEKNPRDKAVVPVFNPVRSQTLVKTEEETAQAVAAEKWSHLSLTRRNLCGNSAQETVMSLSPMTEEIVTKDRLFKAKQETSEEMEQSGEASGKPNRECAPQIPCSTPIATERTVAHLNTLKDRHPGDLWARMHISSLEYAAGDITRKGRKKDKARVSELLQGLSFSGDSDVEKDNEPEIQPAQKKLKVSCFPEKSWTKRDIKPNFPSWSALDSGLLNLKSEKLNPVELFELFFDDETFNLIVNETNNYASQKNVSLEVTVQEMRCVFGVLLLSGFMRHPRREMYWEVSDTDQNLVRDAIRRDRFELIFSNLHFADNGHLDQKDKFTKLRPLIKQMNKNFLLYAPLEEYYCFDKSMCECFDSDQFLNGKPIRIGYKIWCGTTTQGYLVWFEPYQEESTMKVDEDPDLGLGGNLVMNFADVLLERGQYPYHLCFDSFFTSVKLLSALKKKGVRATGTIRENRTEKCPLMNVEHMKKMKRGYFDFRIEENNEIILCRWYGDGIISLCSNAVGIEPVNEVSCCDADNEEIPQISQPSIVKVYDECKEGVAKMDQIISKYRVRIRSKKWYSILVSYMIDVAMNNAWQLHRACNPGASLDPLDFRRFVAHFYLEHNAHLSD
uniprot
proteins
function
FUNCTION: Transposase-derived from PiggyBac DNA transposons. Although it has been fully domesticated and lacks transposase activity, PGBD1 has acquired DNA-binding capability (PubMed:12955498, PubMed:35609796, PubMed:36205081). It preferentially binds in and around genes involved in neuronal development, leading to their transcriptional pausing. Notably, PGBD1 suppresses paraspeckle assembly in neuronal cells (PubMed:36205081). {ECO:0000269|PubMed:12955498, ECO:0000269|PubMed:35609796, ECO:0000269|PubMed:36205081}.
uniprot
proteins
mass_dalton
92515
uniprot
proteins
pubmed
12955498
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
35609796
uniprot
proteins
pubmed
36205081
uniprot
proteins
sequence_length
809
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:36205081}.
uniprot
proteins