Txnrd1
entrez
50493
canonical
uniprot
Q9JMH6
canonical
ensembl
ENSMUSG00000020250
resolver
ensp
ENSMUSP00000020484
resolver
ensp
ENSMUSP00000151629
resolver
ensp
ENSMUSP00000151825
resolver
ensp
ENSMUSP00000152046
resolver
genesymbol
Txnrd1
resolver
genesymbol_syn
Trxr1
resolver
uniprot
Q3UEB7
resolver
uniprot
Q3UK84
resolver
uniprot
Q8CI31
resolver
uniprot
Q99P49
resolver
uniprot
Q9CSV5
resolver
uniprot_entry
TRXR1_MOUSE
resolver
uniprot_sec
Q3UEB7
resolver
uniprot_sec
Q3UK84
resolver
uniprot_sec
Q8CI31
resolver
uniprot_sec
Q99P49
resolver
uniprot_sec
Q9CSV5
resolver
amino_acid_sequence
MPVDDCWLYFPASRGRTFVQTVWVAPTCPNCCWFPGFLPPVPRPPHVPRVLLRGPRGAVLPASRPSKTLPSSSQTPCPTDPCICPPPSTPDSRQEKNTQSELPNKKGQLQKLPTMNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG
uniprot
proteins
ec_number
1.11.1.2
uniprot
proteins
ec_number
1.8.1.9
uniprot
proteins
function
FUNCTION: Reduces disulfide protein thioredoxin (Trx) to its dithiol-containing form. Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation. A selenocysteine residue at the C-terminal active site is essential for catalysis. Also has reductase activity on hydrogen peroxide (H2O2). {ECO:0000250|UniProtKB:Q16881}.
uniprot
proteins
mass_dalton
67084
uniprot
proteins
post_translational_modification
PTM: ISGylated. {ECO:0000250|UniProtKB:Q16881}.
uniprot
proteins
protein_family
Class-I pyridine nucleotide-disulfide oxidoreductase family
uniprot
proteins
pubmed
10721726
uniprot
proteins
pubmed
11060283
uniprot
proteins
pubmed
11737861
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
613
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10721726}.
uniprot
proteins