MAN1C1
entrez
57134
canonical
uniprot
Q9NR34
canonical
ensembl
ENSG00000117643
resolver
ensp
ENSP00000363449
resolver
ensp
ENSP00000363452
resolver
ensp
ENSP00000569143
resolver
ensp
ENSP00000627375
resolver
ensp
ENSP00000724748
resolver
ensp
ENSP00000724753
resolver
enst
ENST00000374329
resolver
enst
ENST00000374332
resolver
genesymbol
MAN1C1
resolver
genesymbol_syn
MAN1A3
resolver
genesymbol_syn
MAN1C
resolver
hgnc
HGNC:19080
resolver
uniprot
A6NGN6
resolver
uniprot
A6NNE2
resolver
uniprot
B2RNP2
resolver
uniprot
Q59G34
resolver
uniprot
Q9Y545
resolver
uniprot_entry
A6NGN6_HUMAN
resolver
uniprot_entry
MA1C1_HUMAN
resolver
uniprot_entry
Q59G34_HUMAN
resolver
uniprot_sec
A6NNE2
resolver
uniprot_sec
B2RNP2
resolver
uniprot_sec
Q9Y545
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by both 1-deoxymannojirimycin and kifunensine.
uniprot
proteins
amino_acid_sequence
MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDLLSLEDWVFNTEAHPLPVNHSDSSGRAWGRH
uniprot
proteins
ec_number
3.2.1.113
uniprot
proteins
function
FUNCTION: Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.
uniprot
proteins
mass_dalton
70911
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:P32906}.
uniprot
proteins
protein_family
Glycosyl hydrolase 47 family
uniprot
proteins
pubmed
10915796
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
630
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type II membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 23..43; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins