Capn8
entrez
170808
canonical
uniprot
Q78EJ9
canonical
ensembl
ENSRNOG00000003468
resolver
ensembl
ENSRNOG00055012655
resolver
ensembl
ENSRNOG00060007746
resolver
ensembl
ENSRNOG00065017838
resolver
ensp
ENSRNOP00000062898
resolver
genesymbol
Capn8
resolver
genesymbol_syn
Cls4
resolver
genesymbol_syn
Ncl2
resolver
uniprot
Q64698
resolver
uniprot
Q78EJ8
resolver
uniprot
Q8K407
resolver
uniprot_entry
CAN8_RAT
resolver
uniprot_sec
Q64698
resolver
uniprot_sec
Q78EJ8
resolver
uniprot_sec
Q8K407
resolver
amino_acid_sequence
MAALAAGVSKQRAVAEGLGSNQNAVKYLGQDFETLRKQCLNSGVLFKDPEFPACPSALGYKDLGPGSPDTQGIVWKRPTELCPNPQFIVGGATRTDIRQGGLGDCWLLAAIASLTLNEKLLYRVLPRDQSFQKDYAGIFHFQFWQYGEWVEVVIDDRLPTKNGQLLFLHSEEGNEFWSALLEKAYAKLNGSYEALVGGSTIEGFEDFTGGISEFYDLKKPPENLYYIIQKALRKGSLLGCSIDVSTAAEAEATTRQKLVKGHAYSVTGVEEVNFHGRPEKLIRLRNPWGEVEWSGAWSDNAPEWNYIDPRRKEELDKKAEDGEFWMSFSDFLKQYSRLEICNLSPDSLSSEEIHKWNLVLFNGRWTRGSTAGGCLNYPGTYWTNPQFKIHLDEVDEDQEEGTSEPCCTVLLGLMQKNRRRQKRIGQGMLSIGYAVYQIPKELESHTDAHLGRDFFLGRQPSTCSSTYMNLREVSSRVRLPPGQYLVVPSTFEPFKDGDFCLRVFSEKKAKALEIGDTVSGHPHEPHPRDMDEEDEHVRSLFEEFVGKDSEISANQLKRVLNEVLSKRTDMKFDGFNINTCREMISLLDSDGTGSLGPMEFKTLWLKIRTYLEIFQEMDHNHVGTIEAHEMRTALKKAGFTLNNQVQQTIAMRYACSKLGVDFNGFVACMIRLETLFKLFRLLDKDQNGIVQLSLAEWLCCVLV
uniprot
proteins
ec_number
3.4.22.53
uniprot
proteins
function
FUNCTION: Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
79555
uniprot
proteins
post_translational_modification
PTM: Undergoes autolytic cleavage between Ala-5 and Ala-6 which gives rise to fragments extending from Ala-6 to the C-terminus, Ala-6 to the EF-hand 2 domain and from Ala-6 to the beginning of domain III. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase C2 family
uniprot
proteins
pubmed
12150941
uniprot
proteins
pubmed
7690035
uniprot
proteins
sequence_length
703
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:7690035}. Golgi apparatus {ECO:0000250}.
uniprot
proteins