Pbk
entrez
52033
canonical
uniprot
Q9JJ78
canonical
ensembl
ENSMUSG00000022033
resolver
ensp
ENSMUSP00000022612
resolver
enst
ENSMUST00000022612
resolver
genesymbol
Pbk
resolver
genesymbol_syn
Topk
resolver
uniprot
Q922V2
resolver
uniprot
Q9D184
resolver
uniprot_entry
TOPK_MOUSE
resolver
uniprot_sec
Q922V2
resolver
uniprot_sec
Q9D184
resolver
activity_regulation
ACTIVITY REGULATION: Activated by phosphorylation. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MEGINNFKTPNKSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRGLSHSPWAVKKISLLCDDHYRTVYQKRLTDEAKILKNLNHPNIIGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALEENGIITDKADVFAFGLTLWEMMTLCIPHVNLPDDDVDEDATFDESDFDDEAYYAALGTRPSINMEELDDSYQKAIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKH
uniprot
proteins
ec_number
2.7.12.2
uniprot
proteins
function
FUNCTION: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
36745
uniprot
proteins
post_translational_modification
PTM: Phosphorylated; in a cell-cycle dependent manner at mitosis. {ECO:0000250}.
uniprot
proteins
protein_family
MAP kinase kinase subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
STE Ser/Thr protein kinase family
uniprot
proteins
pubmed
10781613
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
330
uniprot
proteins