Tmem150a
entrez
232086
canonical
uniprot
Q91WN2
canonical
ensembl
ENSMUSG00000055912
resolver
ensp
ENSMUSP00000063977
resolver
enst
ENSMUST00000069695
resolver
genesymbol
Tmem150a
resolver
genesymbol_syn
Tmem150
resolver
uniprot_entry
T150A_MOUSE
resolver
amino_acid_sequence
MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNESCSPDPAEQGGPKSCCTLDDVPLISKCGTYPPESCLFSLIGNMGAVMVALICLLRYGQLLEQSRHSWINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGTGVAFTAGLLFVCLHCVLFYHGATTPLDMAMAYLRSVLAVIAFITLVLSGVFFLHESSQLQHGAALCEWVFVLDILIFYGTFSYEFGTISSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI
uniprot
proteins
function
FUNCTION: Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex. Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity). May also play a role in fasting-induced catabolism (By similarity). {ECO:0000250|UniProtKB:Q86TG1, ECO:0000250|UniProtKB:Q9QZE9}.
uniprot
proteins
mass_dalton
29066
uniprot
proteins
protein_family
DRAM/TMEM150 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q86TG1}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q86TG1}. Note=Localizes mainly at the plasma membrane; only a minor fraction localizes on intracellular structures. {ECO:0000250|UniProtKB:Q86TG1}.
uniprot
proteins
transmembrane_region
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 109..129; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 212..232; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins