TMEM114
entrez
283953
canonical
uniprot
B3SHH9
canonical
ensembl
ENSG00000232258
resolver
ensp
ENSP00000454261
resolver
ensp
ENSP00000484263
resolver
ensp
ENSP00000485294
resolver
enst
ENST00000568335
resolver
enst
ENST00000620492
resolver
enst
ENST00000624696
resolver
genesymbol
TMEM114
resolver
hgnc
HGNC:33227
resolver
uniprot
A0A096LNY9
resolver
uniprot
H3BM71
resolver
uniprot_entry
A0A096LNY9_HUMAN
resolver
uniprot_entry
H3BM71_HUMAN
resolver
uniprot_entry
TM114_HUMAN
resolver
amino_acid_sequence
MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI
uniprot
proteins
disease_involvement
DISEASE: Note=Chromosomal aberrations involving TMEM114 may be a cause of congenital and juvenile cataracts. Translocation t(16;22) (p13.3;q11.2). {ECO:0000269|PubMed:17492639}.
uniprot
proteins
mass_dalton
24166
uniprot
proteins
protein_family
PMP-22/EMP/MP20 family
uniprot
proteins
pubmed
12107413
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17492639
uniprot
proteins
pubmed
21276448
uniprot
proteins
pubmed
21689651
uniprot
proteins
sequence_length
223
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, tight junction {ECO:0000250|UniProtKB:Q9D563}. Lateral cell membrane {ECO:0000250|UniProtKB:Q9D563}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:Q9D563}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..27; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 106..126; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 134..154; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 189..209; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins