Adm
entrez
11535
canonical
uniprot
P97297
canonical
ensembl
ENSMUSG00000030790
resolver
ensp
ENSMUSP00000033054
resolver
enst
ENSMUST00000033054
resolver
genesymbol
Adm
resolver
uniprot
P97453
resolver
uniprot
Q6GTK2
resolver
uniprot_entry
ADML_MOUSE
resolver
uniprot_sec
P97453
resolver
uniprot_sec
Q6GTK2
resolver
amino_acid_sequence
MKLVSITLMLLGSLAFLGADTAGPDTPSQFRKKWNKWALSRGKRELQASSSYPTGLADETTVPTQTLDPFLDEQNTTGPLQASNQSEAHIRVKRYRQSMNQGSRSNGCRFGTCTFQKLAHQIYQLTDKDKDGMAPRNKISPQGYGRRRRRSLLEVLRSRTVESSQEQTHTAPGPWAHISRLFRI
uniprot
proteins
function
FUNCTION: Adrenomedullin/ADM and proadrenomedullin N-20 terminal peptide/PAMP are peptide hormones that act as potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. {ECO:0000250|UniProtKB:P35318}.; FUNCTION: [Adrenomedullin]: ADM function is mediated by the CALCRL-RAMP2 and CALCRL-RAMP3 receptor complexes with ADM showing the highest potency for the CALCRL-RAMP2 complex. {ECO:0000250|UniProtKB:P35318}.; FUNCTION: [Proadrenomedullin N-20 terminal peptide]: Peptide hormone that act as potent hypotensive and vasodilatator agents by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. Acts as a ligand for Mrgprb2 receptor in mast cells. {ECO:0000250|UniProtKB:P35318}.; FUNCTION: [Proadrenomedullin 9-20 terminal peptide]: Peptide hormone that act as potent hypotensive and vasodilatator agents by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. Acts as a ligand for Mrgprb2 receptor in mast cells. {ECO:0000250|UniProtKB:P35318}.
uniprot
proteins
mass_dalton
20750
uniprot
proteins
protein_family
Adrenomedullin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
8938454
uniprot
proteins
pubmed
9808778
uniprot
proteins
sequence_length
184
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P35318}.
uniprot
proteins