P47802
uniprot
P47802
canonical
amino_acid_sequence
MAAPMELFCWSGGWGLPSVDLDSLAVLTYTRFTGAPLKIHKTSNPWQSPSGTLPALRTSDGKVITVPDKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLIHTFWIDAKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLCGEHKSENEEELEKELYQEARECLTLLSQRLGSQKFFFGDAPASLDAFVFSHLALLLQAKLPSGKLQAHLRGLHNLCAYCTHILNLYFPRDGDEVPLPRQTPAAPETEEEPYRRRTQILSVLAGLAAMVGYALLSGIVSIQRTSPARAPGTRALGLAEEDEED
uniprot
proteins
function
FUNCTION: Involved in transport of proteins into the mitochondrion. Essential for embryonic development. {ECO:0000269|PubMed:9045676}.
uniprot
proteins
mass_dalton
35624
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. {ECO:0000250|UniProtKB:Q13505}.
uniprot
proteins
protein_family
Metaxin family
uniprot
proteins
pubmed
10381257
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7753840
uniprot
proteins
pubmed
8871542
uniprot
proteins
pubmed
9045676
uniprot
proteins
pubmed
9705320
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000269|PubMed:9045676}.
uniprot
proteins
transmembrane_region
TRANSMEM 272..292; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins