Folr2
entrez
14276
canonical
uniprot
Q05685
canonical
ensembl
ENSMUSG00000032725
resolver
ensp
ENSMUSP00000091692
resolver
ensp
ENSMUSP00000147920
resolver
enst
ENSMUST00000094141
resolver
enst
ENSMUST00000210598
resolver
genesymbol
Folr2
resolver
genesymbol_syn
Fbp2
resolver
genesymbol_syn
Folbp2
resolver
uniprot_entry
FOLR2_MOUSE
resolver
amino_acid_sequence
MAWKQTPLLLLVYMVTTGSGRDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCSVNTSQELHKADSRLYFNWDHCGKMEPACKSHFIQDSCLYECSPNLGPWIQQVDQSWRKERFLDVPLCKEDCHQWWEACRTSFTCKRDWHKGWDWSSGINKCPNTAPCHTFEYYFPTPASLCEGLWSHSYKVSNYSRGSGRCIQMWFDSTQGNPNEDVVKFYASFMTSGTVPHAAVLLVPSLAPVLSLWLPG
uniprot
proteins
function
FUNCTION: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
28821
uniprot
proteins
protein_family
Folate receptor family
uniprot
proteins
pubmed
10508523
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15703271
uniprot
proteins
pubmed
1894617
uniprot
proteins
pubmed
8307991
uniprot
proteins
sequence_length
251
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
uniprot
proteins