Pdhb
entrez
289950
canonical
uniprot
P49432
canonical
ensembl
ENSRNOG00000007895
resolver
ensembl
ENSRNOG00055013498
resolver
ensembl
ENSRNOG00060020329
resolver
ensembl
ENSRNOG00065008560
resolver
ensp
ENSRNOP00000010545
resolver
ensp
ENSRNOP00055018787
resolver
ensp
ENSRNOP00060029151
resolver
ensp
ENSRNOP00065010121
resolver
enst
ENSRNOT00055023148
resolver
enst
ENSRNOT00060035467
resolver
enst
ENSRNOT00065013621
resolver
genesymbol
Pdhb
resolver
uniprot
Q6AY95
resolver
uniprot_entry
ODPB_RAT
resolver
uniprot_sec
Q6AY95
resolver
amino_acid_sequence
MAAVAGLVRGPLRQASGLLKRRFHRSAPAAVQLTVREAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSAGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDDNPVVMLENELMYGVAFELPTEAQSKDFLIPIGKAKIERQGTHITVVAHSRPVGHCLEAAAVLSKEGIECEVINLRTIRPMDIEAIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI
uniprot
proteins
ec_number
1.2.4.1
uniprot
proteins
function
FUNCTION: Together with PDHA1 forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex. The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). The E1 subunit catalyzes both the thiamine pyrophosphate (TPP)-dependent decarboxylation of pyruvate and the reductive acetylation of a lipoyl group covalently linked to the lipoyl-bearing domains of E2. {ECO:0000250|UniProtKB:P11177}.
uniprot
proteins
mass_dalton
38982
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2025639
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:P26284}.
uniprot
proteins