Timm8a
entrez
84383
canonical
uniprot
Q9WVA1
canonical
ensembl
ENSRNOG00000064119
resolver
ensembl
ENSRNOG00060019793
resolver
ensembl
ENSRNOG00065006401
resolver
ensp
ENSRNOP00000084461
resolver
ensp
ENSRNOP00060028011
resolver
ensp
ENSRNOP00065007142
resolver
enst
ENSRNOT00000108899
resolver
enst
ENSRNOT00060034171
resolver
enst
ENSRNOT00065009838
resolver
genesymbol
Timm8a
resolver
genesymbol_syn
Ddp1
resolver
genesymbol_syn
Tim8a
resolver
uniprot_entry
TIM8A_RAT
resolver
amino_acid_sequence
MESSSSSSGSALAAVDPQLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD
uniprot
proteins
function
FUNCTION: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11042
uniprot
proteins
protein_family
Small Tim family
uniprot
proteins
pubmed
10611480
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
97
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
uniprot
proteins