Cpz
entrez
83575
canonical
uniprot
O54858
canonical
ensembl
ENSRNOG00000008947
resolver
ensembl
ENSRNOG00055016617
resolver
ensembl
ENSRNOG00060021534
resolver
ensembl
ENSRNOG00065031327
resolver
ensp
ENSRNOP00000012109
resolver
ensp
ENSRNOP00000085858
resolver
ensp
ENSRNOP00055022741
resolver
ensp
ENSRNOP00060030914
resolver
ensp
ENSRNOP00065044480
resolver
enst
ENSRNOT00000113023
resolver
enst
ENSRNOT00055028256
resolver
enst
ENSRNOT00060037512
resolver
enst
ENSRNOT00065054050
resolver
genesymbol
Cpz
resolver
uniprot
A0A8I6A134
resolver
uniprot
O54859
resolver
uniprot_entry
A0A8I6A134_RAT
resolver
uniprot_entry
CBPZ_RAT
resolver
uniprot_sec
O54859
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by 2-mercaptomethyl-3-guanidinoethylthiopropanoic acid (MGTA) and guanidinoethylmercaptosuccinic acid (GEMSA). Inhibited by chelating agents such as EDTA and EGTA (By similarity). {ECO:0000250|UniProtKB:Q66K79}.
uniprot
proteins
amino_acid_sequence
MPTTPLLLAALAALAALAVAAYPSCSPGPDPSGKCQRLASTHSATCVDLHLRTCADAAYNHTSFPTPLEHRSWEAVEASPEYTLLGVLHFLLEGQCNPDLRLLGCSVLAPRCQGGHTQRPCRRVCEGLREACQPAFDAIDMAWPYFLDCTQYFAPEEEGCYDPLEQLRGELDVEEALPSGLPPTFIRFAHHSYAQMVRVLKRTAARCSQVAKTYSIGRSFEGKDLVVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREILIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLASTRGVRTDHIPISQYYWWGKVAPETKAIMKWIQTIPFVLSASLHGGDLVVSYPFDFSKHPHEEKMFSPTPDEKMFKLLARAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYGLWQHNKEPLLNFLEMVHRGIKGVVTDKYGKPVKNARILVKGIRHDVTTAPDGDYWRLLPPGSHIVIAQAPGYSKVMKRVTIPLRMKRAGRVDFILQPLGTGPKNFLPGPSRALPRSLDPQGAPAQLDFEPPRARRQPASGSKPWWWAYFTSLSPHKPRWLLKY
uniprot
proteins
ec_number
3.4.17.-
uniprot
proteins
function
FUNCTION: Specifically cleaves substrates and peptides with C-terminal basic amino acids, especially those containing C-terminal Arg residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. {ECO:0000250|UniProtKB:Q66K79}.
uniprot
proteins
mass_dalton
73082
uniprot
proteins
protein_family
Peptidase M14 family
uniprot
proteins
pubmed
10671522
uniprot
proteins
pubmed
12419858
uniprot
proteins
pubmed
9570147
uniprot
proteins
sequence_length
652
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000250|UniProtKB:Q66K79}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10671522}. Note=Part of the secreted CPZ is bound to the extracellular matrix. {ECO:0000250|UniProtKB:Q66K79}.
uniprot
proteins