TMED5
entrez
50999
canonical
uniprot
Q9Y3A6
canonical
ensembl
ENSG00000117500
resolver
ensp
ENSP00000359305
resolver
ensp
ENSP00000418992
resolver
ensp
ENSP00000471060
resolver
ensp
ENSP00000678423
resolver
enst
ENST00000370290
resolver
genesymbol
TMED5
resolver
hgnc
HGNC:24251
resolver
uniprot
B1AKT4
resolver
uniprot
B2R703
resolver
uniprot
D3DT38
resolver
uniprot
M0R072
resolver
uniprot
Q96AX8
resolver
uniprot_entry
M0R072_HUMAN
resolver
uniprot_entry
TMED5_HUMAN
resolver
uniprot_sec
B1AKT4
resolver
uniprot_sec
B2R703
resolver
uniprot_sec
D3DT38
resolver
uniprot_sec
Q96AX8
resolver
amino_acid_sequence
MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDGAGLDIDFHLASPEGKTLVFEQRKSDGVHTVETEVGDYMFCFDNTFSTISEKVIFFELILDNMGEQAQEQEDWKKYITGTDILDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSMVNLVVMVVVSAIQVYMLKSLFEDKRKSRT
uniprot
proteins
function
FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport. {ECO:0000269|PubMed:19948005}.
uniprot
proteins
mass_dalton
26005
uniprot
proteins
protein_family
EMP24/GP25L family
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
19948005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
229
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:19948005}; Single-pass type I membrane protein {ECO:0000269|PubMed:19948005}. Note=Probably cycles between compartments of the early secretatory pathway.
uniprot
proteins
transmembrane_region
TRANSMEM 197..217; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins