RAP1GAP
entrez
5909
canonical
uniprot
P47736
canonical
ensembl
ENSG00000076864
resolver
ensp
ENSP00000363895
resolver
ensp
ENSP00000363897
resolver
ensp
ENSP00000434033
resolver
ensp
ENSP00000441661
resolver
ensp
ENSP00000547927
resolver
ensp
ENSP00000547928
resolver
ensp
ENSP00000547929
resolver
ensp
ENSP00000547930
resolver
ensp
ENSP00000547931
resolver
ensp
ENSP00000547932
resolver
ensp
ENSP00000547933
resolver
ensp
ENSP00000547934
resolver
ensp
ENSP00000547935
resolver
ensp
ENSP00000547937
resolver
ensp
ENSP00000547939
resolver
ensp
ENSP00000547946
resolver
ensp
ENSP00000547951
resolver
ensp
ENSP00000547955
resolver
ensp
ENSP00000547958
resolver
ensp
ENSP00000603944
resolver
ensp
ENSP00000619983
resolver
ensp
ENSP00000619984
resolver
ensp
ENSP00000619985
resolver
ensp
ENSP00000619987
resolver
ensp
ENSP00000619988
resolver
ensp
ENSP00000619989
resolver
ensp
ENSP00000619991
resolver
ensp
ENSP00000619993
resolver
ensp
ENSP00000619994
resolver
ensp
ENSP00000619996
resolver
ensp
ENSP00000619997
resolver
ensp
ENSP00000619999
resolver
ensp
ENSP00000620000
resolver
ensp
ENSP00000620007
resolver
ensp
ENSP00000620008
resolver
ensp
ENSP00000719720
resolver
enst
ENST00000374763
resolver
genesymbol
RAP1GAP
resolver
genesymbol_syn
KIAA0474
resolver
genesymbol_syn
RAP1GA1
resolver
hgnc
HGNC:9858
resolver
uniprot
J3QSS6
resolver
uniprot
O75062
resolver
uniprot
Q5T3S9
resolver
uniprot
Q5T3T4
resolver
uniprot
Q7Z5S8
resolver
uniprot
Q9UQ51
resolver
uniprot
X6R8W7
resolver
uniprot_entry
RPGP1_HUMAN
resolver
uniprot_entry
X6R8W7_HUMAN
resolver
uniprot_sec
J3QSS6
resolver
uniprot_sec
O75062
resolver
uniprot_sec
Q5T3S9
resolver
uniprot_sec
Q5T3T4
resolver
uniprot_sec
Q7Z5S8
resolver
uniprot_sec
Q9UQ51
resolver
amino_acid_sequence
MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQHMPQLGC
uniprot
proteins
function
FUNCTION: GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000269|PubMed:15141215}.
uniprot
proteins
mass_dalton
73361
uniprot
proteins
mutagenesis
MUTAGEN 100; /note="F->E: Impaired dimerization; when associated with E-173."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 173; /note="L->E: Impaired dimerization; when associated with E-100."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 207; /note="E->A: Reduces GTPase activation."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 267; /note="H->A: Abolishes GTPase activation."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 286; /note="R->A: Reduces GTPase activation."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 287; /note="H->A: Abolishes GTPase activation."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 290; /note="N->A,K: Abolishes GTPase activation."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 291; /note="D->A: Abolishes GTPase activation."; /evidence="ECO:0000269|PubMed:15141215"; MUTAGEN 388; /note="R->A,P: Reduces GTPase activation."; /evidence="ECO:0000269|PubMed:15141215
uniprot
proteins
pubmed
10476970
uniprot
proteins
pubmed
15141215
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
18309292
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
1904317
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9346962
uniprot
proteins
pubmed
9455484
uniprot
proteins
sequence_length
663
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane; Peripheral membrane protein.
uniprot
proteins