Fcamr
entrez
64435
canonical
uniprot
Q2TB54
canonical
ensembl
ENSMUSG00000026415
resolver
ensp
ENSMUSP00000027670
resolver
ensp
ENSMUSP00000108096
resolver
genesymbol
Fcamr
resolver
uniprot
Q2TB55
resolver
uniprot
Q920L8
resolver
uniprot
Q9EQT7
resolver
uniprot_entry
FCAMR_MOUSE
resolver
uniprot_sec
Q2TB55
resolver
uniprot_sec
Q920L8
resolver
uniprot_sec
Q9EQT7
resolver
amino_acid_sequence
MDQGAPAKPSEQKVPSLRTRWEILLLTLCLLHGSSMTPPHRRSHSRWLQAGSPQFRTHLYNVEAHTAPTPLCCWKNSLSGTNALRGPRLVTGNTGGAVTIHCHYAPSSVNRHQRKYWCRLGSPLWICHTVVSTNQYTHPDYRGRAALTDIPQSGLFVVRLLRLSLGDVGLYRCGIGDRNDMLFFSVNLTVSAGPSNTTYAAAPASGEPTTASPGAASSAGNGWTSGITQILEGSGSEWDRTVPTTGTSKTTSSANGRQTLRTARTMVPGTGSREEGSIRAAVPTPEGPSPKSRSMSSTTQGVWLWSTRNSVTPSVTTSEGRRQGTTPETDGPRDETDVRVSPEAPRKTTGTTRPSALISEHVTWETLQDKTEVSKQQMLHSLEELSPAPSAQTLNATCLEVASEEGRSIDGSLENTTEESSPPTPSQLSVAGPVWVSVKGPSMKSALMEGESHTRILTPVSTVLALLLIAALILLKRSLGRQRTSQKKERVPRITLIQMTHFLPDKLPDEGKNFQQSNLLPPQASLTVLENDPRP
uniprot
proteins
function
FUNCTION: Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM. {ECO:0000269|PubMed:11062505}.
uniprot
proteins
mass_dalton
57823
uniprot
proteins
mutagenesis
MUTAGEN 519; /note="L->A: Prevents receptor internalization."; /evidence="ECO:0000269|PubMed:11062505"; MUTAGEN 520; /note="L->A: Prevents receptor internalization."; /evidence="ECO:0000269|PubMed:11062505
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250}.
uniprot
proteins
pubmed
11062505
uniprot
proteins
pubmed
11797105
uniprot
proteins
pubmed
12527391
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16681999
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11062505}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 456..476; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins