Chkb
entrez
12651
canonical
uniprot
O55229
canonical
ensembl
ENSMUSG00000022617
resolver
ensp
ENSMUSP00000023289
resolver
enst
ENSMUST00000023289
resolver
genesymbol
Chkb
resolver
genesymbol_syn
Chetk
resolver
genesymbol_syn
Chetk-beta
resolver
genesymbol_syn
Chkl
resolver
uniprot
Q54AG5
resolver
uniprot_entry
CHKB_MOUSE
resolver
uniprot_entry
Q54AG5_MOUSE
resolver
amino_acid_sequence
MAADGTGVVGGGAVGGGLPKDGLQDAKCPEPIPNRRRASSLSRDAQRRAYQWCREYLGGAWRRARPEELSVCPVSGGLSNLLFRCSLPNHVPSVGGEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLPSRPLKTQELRDPVLSGAIATRMARFHGMEMPFTKEPRWLFGTMERYLKQIQDLPSTSLPQMNLVEMYSLKDEMNSLRKLLDDTPSPVVFCHNDIQEGNILLLSEPDSDDNLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPTDYPTREQQLHFIRHYLAEVQKGEILSEEEQKKREEELLLEISRYSLASHFFWGLWSTLQASMSTIEFGYLEYAQSRFQFYFQQKGQLTSSPSS
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Chkb are a cause of rostrocaudal muscular dystrophy (rmd). The disease is characterized by rapidly progressive muscular dystrophy and neonatal forelimb bone deformity. The dystrophy is only evident in skeletal muscle tissues in an unusual rostral-to-caudal gradient. {ECO:0000269|PubMed:16371353}.
uniprot
proteins
ec_number
2.7.1.32
uniprot
proteins
ec_number
2.7.1.82
uniprot
proteins
function
FUNCTION: Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis. {ECO:0000250|UniProtKB:Q9Y259}.
uniprot
proteins
mass_dalton
45126
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3. {ECO:0000250|UniProtKB:Q9Y259}.
uniprot
proteins
protein_family
Choline/ethanolamine kinase family
uniprot
proteins
pubmed
16371353
uniprot
proteins
pubmed
16490392
uniprot
proteins
pubmed
19236939
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9714798
uniprot
proteins
sequence_length
394
uniprot
proteins