BTBD1
entrez
53339
canonical
uniprot
Q9H0C5
canonical
ensembl
ENSG00000064726
resolver
ensp
ENSP00000261721
resolver
ensp
ENSP00000368713
resolver
genesymbol
BTBD1
resolver
genesymbol_syn
C15orf1
resolver
genesymbol_syn
NS5ATP8
resolver
hgnc
HGNC:1120
resolver
uniprot
A6NMI8
resolver
uniprot
Q9BX71
resolver
uniprot
Q9NWN4
resolver
uniprot_entry
BTBD1_HUMAN
resolver
uniprot_sec
A6NMI8
resolver
uniprot_sec
Q9BX71
resolver
uniprot_sec
Q9NWN4
resolver
amino_acid_sequence
MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRISIVGFGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCYTACATLKGPDSHYGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSIEDGQIPEIIFYT
uniprot
proteins
function
FUNCTION: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312). Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism (By similarity). May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis (By similarity). {ECO:0000250|UniProtKB:P58544, ECO:0000269|PubMed:14528312}.
uniprot
proteins
mass_dalton
52771
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
11179693
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11818025
uniprot
proteins
pubmed
12878161
uniprot
proteins
pubmed
14528312
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
482
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11818025, ECO:0000269|PubMed:12878161}. Note=Localizes to punctate or elongated cytoplasmic bodies. {ECO:0000269|PubMed:11818025, ECO:0000269|PubMed:12878161}.
uniprot
proteins