Hoxa13
entrez
15398
canonical
uniprot
Q62424
canonical
ensembl
ENSMUSG00000038203
resolver
ensp
ENSMUSP00000125221
resolver
enst
ENSMUST00000147595
resolver
genesymbol
Hoxa13
resolver
genesymbol_syn
Hox-1.10
resolver
uniprot_entry
HXA13_MOUSE
resolver
amino_acid_sequence
MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAAAAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPVPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQTQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKLKTTS
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Hoxa13 are the cause of hypodactyly (Hd), a condition characterized by profound deficiency of digital arch structures.
uniprot
proteins
function
FUNCTION: Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. {ECO:0000250}.
uniprot
proteins
mass_dalton
39567
uniprot
proteins
mutagenesis
MUTAGEN 366; /note="I->A: Decreased DNA binding and transcriptional activity."; /evidence="ECO:0000269|PubMed:21829694"; MUTAGEN 370; /note="N->A: Decreased DNA binding and transcriptional activity."; /evidence="ECO:0000269|PubMed:21829694"; MUTAGEN 373; /note="V->A: Decreased DNA binding and transcriptional activity."; /evidence="ECO:0000269|PubMed:21829694
uniprot
proteins
protein_family
Abd-B homeobox family
uniprot
proteins
pubmed
15617687
uniprot
proteins
pubmed
21829694
uniprot
proteins
pubmed
8673126
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins