N4bp3
entrez
303112
canonical
uniprot
Q3LUD3
canonical
ensembl
ENSRNOG00000021731
resolver
ensembl
ENSRNOG00055005202
resolver
ensembl
ENSRNOG00060023801
resolver
ensembl
ENSRNOG00065005304
resolver
ensp
ENSRNOP00000030035
resolver
ensp
ENSRNOP00055006318
resolver
ensp
ENSRNOP00060034125
resolver
ensp
ENSRNOP00065005459
resolver
enst
ENSRNOT00000032386
resolver
enst
ENSRNOT00055008349
resolver
enst
ENSRNOT00060041201
resolver
enst
ENSRNOT00065007833
resolver
genesymbol
N4bp3
resolver
uniprot_entry
N4BP3_RAT
resolver
amino_acid_sequence
MATASGPAGIAMGSVGSLLERQDFSPEELRAALAGSRGSRQPDGLLRKGLGQREFFSYLHLPKKDGKTAKRAPRNEPDYTTLYYREHPRAGDFSKTSLPERGRFDKCRIRPSVFKPPVSTGKGFLSMQSLAAHKGQKLWRSNGSLHTLACHPPLSPGPRASQARAQLLHALSLDEGGPEPSLSDSSSGGSFGRSPGTGPSPFSSSLGHINHLGGSLDRASRSPKESGPLAVLSCLPEPPPPYEFSCPTTEEVAVLPDTCEELKRDLGDQDVSNPFTQVLEERQRLWLSELKRLYVDRLHEVAQKAERSERNLQLQLFMAQQEQRRLRKELRAQQGLAPEPRTSGPPMEADPNARPEEEARWEVCQKTAEISLLKQQLREAQAELAQKLAEIFSLKTQLRGSRAQAQAQDAELARLREAVRSLQEQAPREEAPGSCETDDCKSRGLLGEAGGNEAREGAEQLRAELLQERLRGQEQALRFEQERQTWQEEKERVLRYQREIQGSYMDMYRRNQALEQELRVLREPPTSWSPRLESSKI
uniprot
proteins
function
FUNCTION: Plays a positive role in the antiviral innate immune signaling pathway. Mechanistically, interacts with MAVS and functions as a positive regulator to promote 'Lys-63'-linked polyubiquitination of MAVS and thus strengthens the interaction between MAVS and TRAF2 (By similarity). Also plays a role in axon and dendrite arborization during cranial nerve development (PubMed:24044555). May also be important for neural crest migration and early development of other anterior structures including eye, brain and cranial cartilage (PubMed:24044555). {ECO:0000250|UniProtKB:O15049, ECO:0000269|PubMed:24044555}.
uniprot
proteins
mass_dalton
60048
uniprot
proteins
protein_family
N4BP3 family
uniprot
proteins
pubmed
16522626
uniprot
proteins
pubmed
24044555
uniprot
proteins
sequence_length
537
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle {ECO:0000269|PubMed:24044555}. Cell projection, axon {ECO:0000269|PubMed:24044555}. Cell projection, dendrite {ECO:0000269|PubMed:24044555}. Note=In developing neurons, accumulates in early growth cones and at branching points of axons and dendrites. {ECO:0000269|PubMed:24044555}.
uniprot
proteins