Cd59
entrez
25407
canonical
uniprot
P27274
canonical
ensembl
ENSRNOG00000042821
resolver
ensembl
ENSRNOG00055023884
resolver
ensembl
ENSRNOG00060001969
resolver
ensp
ENSRNOP00000060967
resolver
ensp
ENSRNOP00000082990
resolver
ensp
ENSRNOP00055033323
resolver
ensp
ENSRNOP00060002059
resolver
enst
ENSRNOT00000067085
resolver
enst
ENSRNOT00000111042
resolver
enst
ENSRNOT00055040993
resolver
enst
ENSRNOT00060003073
resolver
genesymbol
Cd59
resolver
genesymbol
Cd59b
resolver
genesymbol_syn
Cd59
resolver
uniprot
A0A8I5ZW00
resolver
uniprot_entry
A0A8I5ZW00_RAT
resolver
uniprot_entry
CD59_RAT
resolver
amino_acid_sequence
MRARRGFILLLLLAVLCSTGVSLRCYNCLDPVSSCKTNSTCSPNLDACLVAVSGKQVYQQCWRFSDCNAKFILSRLEIANVQYRCCQADLCNKSFEDKPNNGAISLLGKTALLVTSVLAAILKPCF
uniprot
proteins
function
FUNCTION: Potent inhibitor of the complement membrane attack complex (MAC) action, which protects self-cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins
mass_dalton
13790
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins
pubmed
1376109
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7528012
uniprot
proteins
sequence_length
126
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P13987}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:P13987}. Secreted {ECO:0000250|UniProtKB:P13987}. Note=Localizes to the cell surface. Soluble form found in a number of tissues. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins