Mon1a
entrez
72825
canonical
uniprot
Q6PDG8
canonical
ensembl
ENSMUSG00000032583
resolver
ensp
ENSMUSP00000035202
resolver
enst
ENSMUST00000035202
resolver
genesymbol
Mon1a
resolver
uniprot
A0A0R4J0D5
resolver
uniprot
Q80UP6
resolver
uniprot
Q9CYS2
resolver
uniprot_entry
A0A0R4J0D5_MOUSE
resolver
uniprot_entry
MON1A_MOUSE
resolver
uniprot_sec
Q80UP6
resolver
uniprot_sec
Q9CYS2
resolver
amino_acid_sequence
MAADMQRKRSSECPEGTLAPSNGQSVERAESPTPGLTQGTEPGAGQEGAMFVHTRSYEDLTELEDREASGDSPKECVGSPPPLATDMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWPEPQGAAGRGAATEPSQEGSTEGEEEDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHADGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDPSFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSILLAHNQLVALVRRKDQFLHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLISTDREDFFAVSDCRRRFQERLRKRGTHLALREALRTPYYSVAQVGIPDLRHFLYKSKSSGLFTSPEIEAPYSSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY
uniprot
proteins
function
FUNCTION: Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (PubMed:17632513). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (By similarity). {ECO:0000250|UniProtKB:Q86VX9, ECO:0000269|PubMed:17632513}.
uniprot
proteins
mass_dalton
62131
uniprot
proteins
protein_family
MON1/SAND family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17114649
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17632513
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
556
uniprot
proteins