DNAJB4
entrez
11080
canonical
uniprot
Q9UDY4
canonical
ensembl
ENSG00000162616
resolver
ensp
ENSP00000359799
resolver
ensp
ENSP00000537158
resolver
ensp
ENSP00000537159
resolver
ensp
ENSP00000609190
resolver
ensp
ENSP00000609191
resolver
ensp
ENSP00000609192
resolver
ensp
ENSP00000609193
resolver
ensp
ENSP00000609194
resolver
ensp
ENSP00000609195
resolver
ensp
ENSP00000627279
resolver
enst
ENST00000370763
resolver
enst
ENST00000867099
resolver
enst
ENST00000867100
resolver
enst
ENST00000939131
resolver
enst
ENST00000939132
resolver
enst
ENST00000939133
resolver
enst
ENST00000939134
resolver
enst
ENST00000939135
resolver
enst
ENST00000939136
resolver
enst
ENST00000957220
resolver
genesymbol
DNAJB4
resolver
genesymbol_syn
DNAJW
resolver
genesymbol_syn
HLJ1
resolver
hgnc
HGNC:14886
resolver
uniprot
B2R824
resolver
uniprot
B4DNN2
resolver
uniprot
Q13431
resolver
uniprot_entry
B4DNN2_HUMAN
resolver
uniprot_entry
DNJB4_HUMAN
resolver
uniprot_sec
B2R824
resolver
uniprot_sec
Q13431
resolver
amino_acid_sequence
MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS
uniprot
proteins
disease_involvement
DISEASE: Congenital myopathy 21 with early respiratory failure (CMYO21) [MIM:620326]: An autosomal recessive muscle disorder characterized by diaphragmatic weakness, respiratory impairment, and spinal rigidity. Disease onset ranges from early childhood to adulthood and severity is variable. Death from respiratory failure may occur in severe cases. Some affected individuals may show developmental delay and hypertrophic cardiomyopathy. {ECO:0000269|PubMed:36264506, ECO:0000269|PubMed:36344539}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877). {ECO:0000269|PubMed:24318877}.
uniprot
proteins
mass_dalton
37807
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15661747
uniprot
proteins
pubmed
16542645
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18837411
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21255413
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24318877
uniprot
proteins
pubmed
36264506
uniprot
proteins
pubmed
36344539
uniprot
proteins
pubmed
9546042
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18837411}. Cell membrane {ECO:0000269|PubMed:16542645}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:36264506}. Note=Cytoplasmic according to PubMed:18837411 and membrane-associated according to PubMed:16542645.
uniprot
proteins