Ms4a1
entrez
12482
canonical
uniprot
P19437
canonical
ensembl
ENSMUSG00000024673
resolver
ensp
ENSMUSP00000126422
resolver
enst
ENSMUST00000169159
resolver
genesymbol
Ms4a1
resolver
genesymbol_syn
Cd20
resolver
genesymbol_syn
Ly-44
resolver
genesymbol_syn
Ms4a2
resolver
uniprot
Q542S5
resolver
uniprot_entry
CD20_MOUSE
resolver
uniprot_entry
Q542S5_MOUSE
resolver
amino_acid_sequence
MSGPFPAEPTKGPLAMQPAPKVNLKRTSSLVGPTQSFFMRESKALGAVQIMNGLFHITLGGLLMIPTGVFAPICLSVWYPLWGGIMYIISGSLLAAAAEKTSRKSLVKAKVIMSSLSLFAAISGIILSIMDILNMTLSHFLKMRRLELIQTSKPYVDIYDCEPSNSSEKNSPSTQYCNSIQSVFLGILSAMLISAFFQKLVTAGIVENEWKRMCTRSKSNVVLLSAGEKNEQTIKMKEEIIELSGVSSQPKNEEEIEIIPVQEEEEEEAEINFPAPPQEQESLPVENEIAP
uniprot
proteins
function
FUNCTION: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. {ECO:0000250|UniProtKB:P11836}.
uniprot
proteins
mass_dalton
31958
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250}.
uniprot
proteins
protein_family
MS4A family
uniprot
proteins
pubmed
14688067
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20038800
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2461992
uniprot
proteins
pubmed
8450218
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P11836}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P11836}. Cell membrane {ECO:0000250|UniProtKB:P11836}; Lipid-anchor {ECO:0000250|UniProtKB:P11836}. Note=Constitutively associated with membrane rafts. {ECO:0000250|UniProtKB:P11836}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 69..89; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 112..132; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 183..203; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins