Acp4
entrez
100503991
canonical
uniprot
D3YTS9
canonical
ensembl
ENSMUSG00000012777
resolver
ensp
ENSMUSP00000103578
resolver
ensp
ENSMUSP00000112922
resolver
enst
ENSMUST00000118216
resolver
genesymbol
Acp4
resolver
genesymbol_syn
Acpt
resolver
uniprot_entry
PPAT_MOUSE
resolver
amino_acid_sequence
MAEPGSQGHTVGPLLLLLLLLLPRALPEGPLLFVALVFRHGDRAPLASYPTDPHKEAASTLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPEYKREEVYIRSTDFDRTLESAQANLAGLFPEAAPGSPETDWKPIPVHTVPVSEDKLLRFPMRSCPRYHELLRESTEAADYQEALEGWTDFLTRLGNFTGLSLVGEPLRRAWKVLDTLICQRAHGLDLPSWASPDVLRTLSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRTQRLGLPLKMVMYSAHDSTLLALQGALGLYDGNTPPYAACMAFEFRGSSREPEEEDGENVTVSLIYRNDTSRPPLPLRVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPATVPLLAGAVAVLAVLSLGLGLLAWRPRCLRALGGTV
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Protein tyrosine phosphatase that dephosphorylates the receptor tyrosine-protein kinase ERBB4, thereby inhibiting its ligand-induced proteolytic cleavage (By similarity). Involved in odontogenesis (PubMed:27843125). Regulates odontoblast cell fate via its extracellular catalytic domain by inhibiting proliferation and promoting differentiation (PubMed:26547858). {ECO:0000250|UniProtKB:Q9BZG2, ECO:0000269|PubMed:26547858, ECO:0000269|PubMed:27843125}.
uniprot
proteins
mass_dalton
46405
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250|UniProtKB:Q9BZG2}.
uniprot
proteins
protein_family
Histidine acid phosphatase family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
26547858
uniprot
proteins
pubmed
27843125
uniprot
proteins
sequence_length
425
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 393..413; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins