Kif1a
entrez
363288
canonical
uniprot
F1M4A4
canonical
ensembl
ENSRNOG00000023993
resolver
ensembl
ENSRNOG00055009721
resolver
ensembl
ENSRNOG00060008353
resolver
ensembl
ENSRNOG00065020515
resolver
ensp
ENSRNOP00000038927
resolver
ensp
ENSRNOP00000080676
resolver
ensp
ENSRNOP00000087220
resolver
ensp
ENSRNOP00000106342
resolver
ensp
ENSRNOP00055013312
resolver
ensp
ENSRNOP00060010669
resolver
ensp
ENSRNOP00065027939
resolver
enst
ENSRNOT00000036061
resolver
enst
ENSRNOT00000106149
resolver
enst
ENSRNOT00000120091
resolver
enst
ENSRNOT00055016517
resolver
enst
ENSRNOT00060013958
resolver
enst
ENSRNOT00065034797
resolver
genesymbol
Kif1a
resolver
uniprot
A0A8I5ZRB3
resolver
uniprot
A0A8I6A6V5
resolver
uniprot
A0A8L2QJN2
resolver
uniprot_entry
A0A8I5ZRB3_RAT
resolver
uniprot_entry
A0A8I6A6V5_RAT
resolver
uniprot_entry
A0A8L2QJN2_RAT
resolver
uniprot_entry
KIF1A_RAT
resolver
amino_acid_sequence
MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDTNTVPGGPKLTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGVTRVGREDAERRQDIVLSGHFIKEEHCIFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHPEQARQERERTPCAETPAEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWKWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAAKDRETRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVVEDCDNVVTGGDPFYDRFPWFRLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPVVGMSRSGTSQEELRIVEGQGQGADAGPSADEVNNNTCSAVPPEGLLDSPEKAALDGPLDTALDHLRLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTKSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSTMTRPSPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIRWKEVRELVVGRIRNTPETDEALIDPNILSLNILSSGYVHPAQDDRQFLDSDIPRTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRATEGNRVTGVYELSLCHVADAGSPGMQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETTQRPVPEVLSPASSEDSESRSSSGASSPLSAEGQPSPLEVPNERQRELAVKCLRLLMHTFNREYTHSHVCISASESKLSEMSVTLMRDPSMSPLGAATLTPSSTCPSLIEGRYGATDVRTPQPCSRPASPEPELLPELDSKKTPSPVRATETEKEPQRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDTVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRRRSAQMRV
uniprot
proteins
ec_number
5.6.1.3
uniprot
proteins
function
FUNCTION: Kinesin motor with a plus-end-directed microtubule motor activity, involved in anterograde axonal transport of synaptic vesicle precursors (By similarity). Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons (PubMed:29166604, PubMed:30021165). The interaction calcium-dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites (PubMed:30021165). {ECO:0000250|UniProtKB:P33173, ECO:0000269|PubMed:29166604, ECO:0000269|PubMed:30021165}.
uniprot
proteins
mass_dalton
192934
uniprot
proteins
mutagenesis
MUTAGEN 723..731; /note="WKWYQFTSL->AKAAQATSA: Abolishes interaction with CALM1. Decreases interaction with SYT4 and SYT11. Abolishes location to neuronal dense core vesicles."; /evidence="ECO:0000269|PubMed:30021165
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
protein_family
Unc-104 subfamily
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
19338388
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
29166604
uniprot
proteins
pubmed
30021165
uniprot
proteins
sequence_length
1707
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q12756}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q12756}. Cell projection, axon {ECO:0000250|UniProtKB:P33173}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P33173}. Synapse {ECO:0000250|UniProtKB:P33173}. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane {ECO:0000269|PubMed:29166604, ECO:0000269|PubMed:30021165}; Peripheral membrane protein {ECO:0000305|PubMed:30021165}; Cytoplasmic side {ECO:0000305|PubMed:30021165}. Note=Within neuronal cells concentrated in the axon, with smaller amounts in the perinuclear and synaptic regions (By similarity). Expressed in distal regions of neurites. {ECO:0000250|UniProtKB:P33173, ECO:0000250|UniProtKB:Q12756}.
uniprot
proteins