Cldn17
entrez
239931
canonical
uniprot
Q8BXA6
canonical
ensembl
ENSMUSG00000055811
resolver
ensp
ENSMUSP00000066427
resolver
enst
ENSMUST00000069549
resolver
genesymbol
Cldn17
resolver
uniprot_entry
CLD17_MOUSE
resolver
amino_acid_sequence
MAFYPLQIAGLVLGFFGLVGTIGTTLLPQWRVSAFIGSNIIIFERIWEGLWMNCIQQAMVTLQCKFYNSILALPPVLEAARALMCVAVALALVALIIGICGMKQLQCTGSSERVKAYLLGTSGVLFILTGIFVLIPVSWTANIIIRDFYDPTVHAGQKRELGGALFLGWATAAVLFIGGGLLCGYCCCNRKERWHRYPVPAYRVPQKDNQRNVTVPRKSSTSYV
uniprot
proteins
function
FUNCTION: Channel-forming tight junction protein with selectivity for anions, including chloride and hydrogencarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability. {ECO:0000250|UniProtKB:P56750}.
uniprot
proteins
mass_dalton
24653
uniprot
proteins
protein_family
Claudin family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
22402829
uniprot
proteins
sequence_length
224
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, tight junction {ECO:0000269|PubMed:22402829}. Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 125..145; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins