Srpra
entrez
67398
canonical
uniprot
Q9DBG7
canonical
ensembl
ENSMUSG00000032042
resolver
ensp
ENSMUSP00000034541
resolver
enst
ENSMUST00000034541
resolver
genesymbol
Srpra
resolver
genesymbol_syn
Srpr
resolver
uniprot
Q8VC45
resolver
uniprot
Q921H1
resolver
uniprot_entry
SRPRA_MOUSE
resolver
uniprot_sec
Q8VC45
resolver
uniprot_sec
Q921H1
resolver
amino_acid_sequence
MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKTKEKAKNNKKRGAKKEGSDGTLATSKTAPAEKSGLSAGPENGELSKEELIRRKREEFIQKHGKGLDKSSKSTKSDTPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGPGGQLQDLDCSSSDDEGATQNTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLTALHPPEKHGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA
uniprot
proteins
function
FUNCTION: Component of the SRP (signal recognition particle) receptor (By similarity). Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity). Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SRP subunit SRP54 (By similarity). SRP receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER (By similarity). {ECO:0000250|UniProtKB:P08240}.
uniprot
proteins
mass_dalton
69623
uniprot
proteins
protein_family
GTP-binding SRP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
636
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P32916}; Peripheral membrane protein {ECO:0000250|UniProtKB:P32916}; Cytoplasmic side {ECO:0000250|UniProtKB:P32916}. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain. {ECO:0000250|UniProtKB:P32916}.
uniprot
proteins