LRRC70
entrez
100130733
canonical
uniprot
Q7Z2Q7
canonical
ensembl
ENSG00000186105
resolver
ensp
ENSP00000399441
resolver
enst
ENST00000334994
resolver
genesymbol
LRRC70
resolver
hgnc
HGNC:35155
resolver
uniprot
Q6ZWI5
resolver
uniprot_entry
LRR70_HUMAN
resolver
uniprot_sec
Q6ZWI5
resolver
amino_acid_sequence
MCGLQFSLPCLRLFLVVTCYLLLLLHKEILGCSSVCQLCTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLGLRDWLASSAITLNIYCQNPPSMRGRALRYINITNCVTSSINVSRAWAVVKSPHIHHKTTALMMAWHKVTTNGSPLENTETENITFWERIPTSPAGRFFQENAFGNPLETTAVLPVQIQLTTSVTLNLEKNSALPNDAASMSGKTSLICTQEVEKLNEAFDILLAFFILACVLIIFLIYKVVQFKQKLKASENSRENRLEYYSFYQSARYNVTASICNTSPNSLESPGLEQIRLHKQIVPENEAQVILFEHSAL
uniprot
proteins
function
FUNCTION: Renders cells highly sensitive to the activation by cytokines and lipopolysaccharide (LPS). {ECO:0000269|PubMed:12767927}.
uniprot
proteins
mass_dalton
70301
uniprot
proteins
pubmed
12767927
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
sequence_length
622
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 527..547; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins