G3UYQ4
uniprot
G3UYQ4
canonical
amino_acid_sequence
MASEEKTEELHPFTDIFNEDETDRNCLLSKPTCFIIFGKPGAGKTTLARNIAQAWKCIRVEALSVLEEHIAAEKETGAMLQSLLVSGHSIPDELVTKLILEKIKSPEVAHFGYILTEMPSLAQDNMTSLKQIELVKNLELQPDIIINIKCSDYDLCQRTCGQRQHSTTGYVYTREQWDPEIIESRRRKKRDFPKEGKSEEEEEEEEQEEEEAFIAEMQMVAEILQHLVQRPEDYLENVEITVKLYKELLLSALEEVMAEHNPQYLIELDGNKSPEELFMTVIERLKYLNVRRAAVITKLQGTEEEMTDIIDTEELFRTVSSYKLIAPRYRWYRSKWARSCPVSLKDGNIYSGAADYTVSFLGKMYCLSSEETLKLFSLNPRPFLLPPMPLPPCKVFIFGPEHIGKTTLANLIAEHFKAKVIDYAKLVQPRFDSAREKLIKDTITEATNTAIKVVQQRLLNEKQAKQQEERTLKELQVQYSKREYNDFLSKSSEELPSLENTGSKLSSLEIGQEDKSKSETTITGDQVKDVSTEESIEEVTENHPEVFAILEDTLRHAKELNFEQPHDKQAEILEEVIKETEDNKNRFPGAPKHGGWIVENFPLVRELWLSLIEKALLPDLVVYLSDAESNGKHVLNRLYLKNKAEIDGKILERLQEEAQAKKREEEEIRKVKEEELRLEEEKQRLMELATKKSKGRHRLTTLVAHHLALPYPDYPDNEAEEEVEDSEIHEESEAQEIPEYTRGSSLPEASETSETPEGDHEPEAEFKPPGDTAVEAETEKDPKEGLGSEDLLKVMLPEFPEDGYPNVPEMEPLKEVLNNHILSWKQLEQTIMDNVVSTLTVDVSNKTPQELLQRVVETMERPFKYSAWELNAEDYEEEAEDYQAETEIDEEQEEEEEEEEEGEEKIKEKRRHMGDTKHFCPVVLKENFVLQPGNPDEAVKYREKIYYFSSTEAKEKFLEHPEDYVSQNEPLKAPPLRICLLGPHGSGKTVCARKLAENFGIFHIQFDEFLQEKMLLKAERKFGPEFEDDSEEEQLVKQELEELAAQANVKIEEDTTKKQLPDVQLTEEEEAIKLSLTDNEPLPSEILDSILSEWWLKEPIRSTGFILDGFPRHPEEAQFLGERGFFPDAAVIIQVDDQDIFDRLLPAQVQKWKTKQHKKLERKKLIKDLKTKIKEDMVAKRRAELILEREKKRREDGTFRDEDEFSDEDADYEDDIENILEEEFPKDEEEMSEEDEEQEADATERLRNELGEKFETETNNIQSIQDEFDKVLIPIIMVNGARKMHIVQYVMNMKLKPLVENRESIFEKCYPVSSHLAHKMLSYTYKHMSSFGYWDPVKLSEGETIKPVENAENPLNPVIHRHYIYFLSNKQTKEKFMMNPIKYIRQPKPKATMPVRIMIVGPPKSGKTTVAKKLASDYGLRCLSVGDALRGMLNNHPDSELSLMLNWHLHKGKTVPDELAIQALDISLMESVCNTIGVVIDGYPVTPHQMDLLEARSIIPMVIFELHVPSKEIFKRLLLEKKTEQSMSYPLHNSSQIIAYKNAKYHKNINEIRQFYQKQHQNWHVIDGFHSKWWVWNEVLKDIQQMNKYIQTYMKKIKEGKAACIDKLCITPEELIARLGEFKQFCPVSLAESNELIDCSVTSSLEFAAEFRGHYYKMSSQEKLNKFLKDPELYVPPLAPHPLPPDDLLPKRLTLSELKSRFPKCAELQGYCPVTYQDGKQRYEALVPGNIRYALEYRNCIYICESEEKLQKFMRSPMQYWNQKLPRKLPPLKESIHLTSLPLPGYLEQGTATSLIKAMNAAGNLKPKLPFLSVRRSVLLYIAFHLKAFNPKGSEYSRKKYKKKLEQFVERCELITYLSSKMTRKYKEPQFRAIDFDHKLQTFLSLKNIDPVTG
uniprot
proteins
ec_number
2.7.4.4
uniprot
proteins
ec_number
2.7.4.6
uniprot
proteins
function
FUNCTION: Broad-specificity nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. For this activity shows the following substrate preference CDP > UDP > ADP > TDP. {ECO:0000250|UniProtKB:Q5TCS8}.
uniprot
proteins
mass_dalton
219534
uniprot
proteins
protein_family
Adenylate kinase family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
37713809
uniprot
proteins
pubmed
38171079
uniprot
proteins
sequence_length
1894
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q5TCS8}. Nucleus {ECO:0000250|UniProtKB:Q5TCS8}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:37713809}.
uniprot
proteins