Dcph1
entrez
73419
canonical
uniprot
A6H630
canonical
ensembl
ENSMUSG00000061759
resolver
ensp
ENSMUSP00000093581
resolver
genesymbol
Dcph1
resolver
genesymbol_syn
Armt1
resolver
uniprot
Q499H1
resolver
uniprot
Q99M05
resolver
uniprot
Q9D9L4
resolver
uniprot_entry
ARMT1_MOUSE
resolver
uniprot_sec
Q499H1
resolver
uniprot_sec
Q99M05
resolver
uniprot_sec
Q9D9L4
resolver
amino_acid_sequence
MAESPAFLSAKDEGSFAYLTIKDRTPQILTKVIDTLHRHKSEFFEKHGEEGIEAEKKAISLLSKLRNELQTDKPITPLVDKCVDTHIWNQYLEYQRSLLNEGDGEPRWFFSPWLFVECYMYRRIHEAIMQSPPIHDFDVFKESKEENFFESQGSIDALCSHLLQLKPVKGLREEQIQDEFFKLLQISLWGNKCDLSLSGGESSSQKANIINCLQDLKPFILINDTESLWALLSKLKKTVETPVVRVDIVLDNSGFELITDLVLADFLFSSELATEIHFHGKSIPWFVSDVTEHDFNWIVEHMKSSNLESMSTCGACWEAYARMGRWAYHDHAFWTLPHPYCVMPQVAPDLYAELQKAHLILFKGDLNYRKLMGDRKWKFTFPFHQALSGFHPAPLCSIRTLKCELQVGLQPGQAEQLTASDPHWLTTGRYGILQFDGPL
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
ec_number
3.1.3.-
uniprot
proteins
function
FUNCTION: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity). Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity). Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues (By similarity). Possibly methylates PCNA, suggesting it is involved in the DNA damage response (By similarity). {ECO:0000250|UniProtKB:Q04371, ECO:0000250|UniProtKB:Q9H993}.
uniprot
proteins
mass_dalton
50549
uniprot
proteins
post_translational_modification
PTM: Automethylated. {ECO:0000250|UniProtKB:Q9H993}.
uniprot
proteins
protein_family
Damage-control phosphatase family
uniprot
proteins
protein_family
Sugar phosphate phosphatase III subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
439
uniprot
proteins