Acot5
entrez
217698
canonical
uniprot
Q6Q2Z6
canonical
ensembl
ENSMUSG00000042540
resolver
ensp
ENSMUSP00000042019
resolver
ensp
ENSMUSP00000072322
resolver
enst
ENSMUST00000046422
resolver
enst
ENSMUST00000072505
resolver
genesymbol
Acot5
resolver
genesymbol_syn
BC016076
resolver
uniprot
E9QKJ5
resolver
uniprot
F6RZR3
resolver
uniprot
Q91YQ6
resolver
uniprot_entry
ACOT5_MOUSE
resolver
uniprot_entry
F6RZR3_MOUSE
resolver
uniprot_entry
Q91YQ6_MOUSE
resolver
uniprot_sec
E9QKJ5
resolver
amino_acid_sequence
MVPTVSLEPTGHSCWDEPLSIAVRGLAPEQPVTLRTALRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYKYDDLPKVIDILHLEYFEEAVTYLLSHPQVKGPGVGLLGISKGAELSLSMASFLKGITAAVVINGATVNVISTLYYKEESLPGLGMHLERIKVTKDGFKDIIDILNVPLEAPDQKSLIPLERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIVCYPKTGHHIEPPYIPWSIAAPHSYFDKPILLGGEPRAHAMAQVDAWQRLQTFFHKHLSGDKRPSPAKL
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16940157). Mainly active on medium-chain acyl-CoAs (PubMed:15007068). Seems to be involved in intraperoxisomal regulation of acyl-CoA levels, but not CoASH levels (PubMed:15007068). May have a function in termination of beta-oxidation of fatty acids (PubMed:15007068). {ECO:0000269|PubMed:15007068, ECO:0000303|PubMed:16940157}.
uniprot
proteins
mass_dalton
46573
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid metabolism. {ECO:0000305|PubMed:15007068, ECO:0000305|PubMed:16940157}.
uniprot
proteins
protein_family
C/M/P thioester hydrolase family
uniprot
proteins
pubmed
15007068
uniprot
proteins
pubmed
16940157
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
421
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000269|PubMed:15007068}.
uniprot
proteins