Nagpa
entrez
27426
canonical
uniprot
Q8BJ48
canonical
ensembl
ENSMUSG00000023143
resolver
ensp
ENSMUSP00000023911
resolver
ensp
ENSMUSP00000291051
resolver
enst
ENSMUST00000023911
resolver
genesymbol
Nagpa
resolver
uniprot
Q3UUT5
resolver
uniprot
Q8CHQ8
resolver
uniprot
Q9QZE6
resolver
uniprot_entry
NAGPA_MOUSE
resolver
uniprot_sec
Q3UUT5
resolver
uniprot_sec
Q8CHQ8
resolver
uniprot_sec
Q9QZE6
resolver
amino_acid_sequence
MAAPRGPGLFLIPALLGLLGVAWCSLSFGVSRDDDLLLPYPLARRRPSRDCARVRSGSPEQESWPPPPTNPGASHHAAVRTFVSHFEGRAVAGHLTRVADPLRTFSVLEPGGAGGCAQKRRATVEDTAVPAGCRIAQNGGFFRMSTGECLGNVVSDGRLVSSSGGLQNAQFGIRRDGTIVTGYLSEEEVLDPVNPFVQLLSGVVWLIRNGNIYINESQAIECDETQETGSFSKFVNVMSARTAVGHDREGQLILFHADGQTEQRGLNLWEMAEFLRQQDVVNAINLDGGGSATFVLNGTLASYPSDHCQDNMWRCPRQVSTVVCVHEPRCQPPDCSGHGTCVDGHCECTSHFWRGEACSELDCGPSNCSQHGLCTETGCHCDAGWTGSNCSEECPLGWYGPGCQRPCQCEHQCSCDPQTGNCSISQVRQCLQPTEATPRAGELASFTRTTWLALTLTLIFLLLISTGVNVSLFLGSRAERNRHLDGDYVYHPLQEVNGEALTAEKEHMEETSNPFKD
uniprot
proteins
ec_number
3.1.4.45
uniprot
proteins
function
FUNCTION: Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N-acetylglucosaminyltransferases.
uniprot
proteins
mass_dalton
56044
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.
uniprot
proteins
post_translational_modification
PTM: The precursor is cleaved and activated in the trans-Golgi network by a furin endopeptidase. {ECO:0000250}.
uniprot
proteins
pubmed
10551838
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
517
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network {ECO:0000250}. Note=Cis/medial Golgi.
uniprot
proteins
transmembrane_region
TRANSMEM 454..474; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins