Popdc2
entrez
64082
canonical
uniprot
Q9ES82
canonical
ensembl
ENSMUSG00000022803
resolver
ensp
ENSMUSP00000023494
resolver
ensp
ENSMUSP00000110387
resolver
ensp
ENSMUSP00000288825
resolver
ensp
ENSMUSP00000288826
resolver
ensp
ENSMUSP00000288828
resolver
enst
ENSMUST00000023494
resolver
enst
ENSMUST00000114739
resolver
genesymbol
Popdc2
resolver
genesymbol_syn
Pop2
resolver
uniprot
F8WJG9
resolver
uniprot
Q6P3F7
resolver
uniprot_entry
F8WJG9_MOUSE
resolver
uniprot_entry
POPD2_MOUSE
resolver
uniprot_entry
Q6P3F7_MOUSE
resolver
amino_acid_sequence
MSANGSSVAQLLWQPPVCRSWKPDVEGAVYHLANCFLLMGFMAGSGVYGCFYLFGILGPGYLCCVLWGWFDACGLDIVLWNVLLTVACLLQLAQLVYRVRVNTLPEEFNLLYRTLCLPLQVPLQVYKEIVHCCHEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLHPSEEGTFQVTLTAETECSYISWPRKNLYLLLNRERYISRLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLSPSASDGEPESEKDDEEALEAAVSPAQARPICIVPTPPCSAPPATTNFPVPLPRARMPRMPRPDSGNLASRRPLQNSSQVMSRSQAPLAPIHTPEL
uniprot
proteins
function
FUNCTION: Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density. {ECO:0000250|UniProtKB:Q6JWV8, ECO:0000269|PubMed:22354168}.
uniprot
proteins
mass_dalton
41252
uniprot
proteins
mutagenesis
MUTAGEN 184; /note="D->A: Almost abolishes cAMP-binding."; /evidence="ECO:0000269|PubMed:22354168
uniprot
proteins
protein_family
Popeye family
uniprot
proteins
pubmed
10882522
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22354168
uniprot
proteins
sequence_length
367
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q9HBU9}.
uniprot
proteins
transmembrane_region
TRANSMEM 36..56; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 77..97; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins