Gjc1
entrez
266706
canonical
uniprot
A4GG66
canonical
ensembl
ENSRNOG00000048838
resolver
ensembl
ENSRNOG00055028838
resolver
ensembl
ENSRNOG00060012323
resolver
ensembl
ENSRNOG00065029938
resolver
ensp
ENSRNOP00000076255
resolver
ensp
ENSRNOP00000081758
resolver
ensp
ENSRNOP00000087322
resolver
ensp
ENSRNOP00000094267
resolver
ensp
ENSRNOP00000096467
resolver
ensp
ENSRNOP00000099947
resolver
ensp
ENSRNOP00000106010
resolver
ensp
ENSRNOP00000107543
resolver
ensp
ENSRNOP00000108487
resolver
ensp
ENSRNOP00000109015
resolver
ensp
ENSRNOP00055041125
resolver
ensp
ENSRNOP00055041130
resolver
ensp
ENSRNOP00055041133
resolver
ensp
ENSRNOP00055041135
resolver
ensp
ENSRNOP00055041141
resolver
ensp
ENSRNOP00060016453
resolver
ensp
ENSRNOP00060016456
resolver
ensp
ENSRNOP00060016459
resolver
ensp
ENSRNOP00060016464
resolver
ensp
ENSRNOP00060016466
resolver
ensp
ENSRNOP00065042554
resolver
ensp
ENSRNOP00065042556
resolver
ensp
ENSRNOP00065042560
resolver
ensp
ENSRNOP00065042569
resolver
ensp
ENSRNOP00065042572
resolver
enst
ENSRNOT00000093570
resolver
enst
ENSRNOT00000096574
resolver
enst
ENSRNOT00000108179
resolver
enst
ENSRNOT00000116881
resolver
enst
ENSRNOT00000117898
resolver
enst
ENSRNOT00000151731
resolver
enst
ENSRNOT00000160044
resolver
enst
ENSRNOT00000162959
resolver
enst
ENSRNOT00000165769
resolver
enst
ENSRNOT00000170911
resolver
enst
ENSRNOT00055049937
resolver
enst
ENSRNOT00055049943
resolver
enst
ENSRNOT00055049948
resolver
enst
ENSRNOT00055049952
resolver
enst
ENSRNOT00055049962
resolver
enst
ENSRNOT00060020873
resolver
enst
ENSRNOT00060020877
resolver
enst
ENSRNOT00060020882
resolver
enst
ENSRNOT00060020887
resolver
enst
ENSRNOT00060020891
resolver
enst
ENSRNOT00065051699
resolver
enst
ENSRNOT00065051701
resolver
enst
ENSRNOT00065051707
resolver
enst
ENSRNOT00065051719
resolver
enst
ENSRNOT00065051723
resolver
genesymbol
Gjc1
resolver
genesymbol_syn
Gja7
resolver
uniprot_entry
CXG1_RAT
resolver
amino_acid_sequence
MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELDDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEEHLPADLETLQREIRMAQERLDLAIQAYHHQNNPHGPREKKAKVGSKSGSNKSSISSKSGDGKTSVWI
uniprot
proteins
function
FUNCTION: Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage (PubMed:12011467). Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response (By similarity). {ECO:0000250|UniProtKB:P36383, ECO:0000269|PubMed:12011467}.
uniprot
proteins
mass_dalton
45666
uniprot
proteins
protein_family
Connexin family
uniprot
proteins
protein_family
Gamma-type subfamily
uniprot
proteins
pubmed
12011467
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17328669
uniprot
proteins
sequence_length
396
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, gap junction {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 176..198; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins