Rhag
entrez
65207
canonical
uniprot
Q7TNK7
canonical
ensembl
ENSRNOG00000050121
resolver
ensp
ENSRNOP00000065437
resolver
genesymbol
Rhag
resolver
genesymbol_syn
Rh50
resolver
uniprot
O88300
resolver
uniprot_entry
RHAG_RAT
resolver
uniprot_sec
O88300
resolver
amino_acid_sequence
MRFKFSLIALSLEVVMIVSFALFVEYETSQNGSQKSASQQNASQQNAAAQQNASQQGNASSPAKEDQFFQLYPLFQHVHVMIFVGFGFLMTFLKKYGFSGVGFNLFLAALGLQWGTIVQGLLHSHGLKFPFRIKNMINADFSTATVLISFGAVLGKTSPIQMIIMTILEIAVFAGNEHLVTEIFKASDTGASMTIHAFGAYFGLAVAGVLYRSGLKHGHPNEESVYHSDLFAMIGTLFLWMFWPSFNSAIAQPENNQYRAIVNTYMSLAACVITAYALSSLVERRGRLDMVHIQNATLAGGVAVGTCADMEIPLYFAMTIGSIAGIISVLGYKFLSPLLAHKLMIHDTCGVHNLHGLPGVFGGLASIVAISWGKSTVSTMAMQATALGSSIGSAIVGGLVTGLILKLPVWNQPPDEYCFDDSVSWKVPKYRELDNYFFQHVTHNHVEHEV
uniprot
proteins
function
FUNCTION: Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Heterotrimer with RHCE (RHAG)2(RHCE), that transports ammonium and its related derivative methylammonium, in both neutral and ionic forms, across the erythrocyte membrane. The transport of NH4(+) is electrogenic and masks the NH3 transport. Also, may act as a CO2 channel. Moreover in erythrocyte, regulates RHD membrane expression and is associated with rhesus blood group antigen expression. {ECO:0000250|UniProtKB:Q02094}.
uniprot
proteins
mass_dalton
49062
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250|UniProtKB:Q02094}.
uniprot
proteins
protein_family
Ammonium transporter (TC 2.A.49) family
uniprot
proteins
protein_family
Rh subfamily
uniprot
proteins
pubmed
16227429
uniprot
proteins
pubmed
16641100
uniprot
proteins
pubmed
9705835
uniprot
proteins
sequence_length
450
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q02094}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q02094}. Note=Localization at the plasma membrane is regulated by ANK1. {ECO:0000250|UniProtKB:Q02094}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..25; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 135..155; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 160..180; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 290..307; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 312..332; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 350..370; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 385..405; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins