Mettl13
entrez
71449
canonical
uniprot
Q91YR5
canonical
ensembl
ENSMUSG00000026694
resolver
ensp
ENSMUSP00000028017
resolver
ensp
ENSMUSP00000262225
resolver
genesymbol
Mettl13
resolver
genesymbol_syn
EEF1AKNMT
resolver
genesymbol_syn
FEAT
resolver
uniprot
Q3TF24
resolver
uniprot
Q3TFY3
resolver
uniprot
Q69ZX4
resolver
uniprot
Q8BWN2
resolver
uniprot
Q8BX81
resolver
uniprot_entry
EFNMT_MOUSE
resolver
uniprot_sec
Q3TF24
resolver
uniprot_sec
Q3TFY3
resolver
uniprot_sec
Q69ZX4
resolver
uniprot_sec
Q8BWN2
resolver
uniprot_sec
Q8BX81
resolver
amino_acid_sequence
MNLLPKSSKEFGSADYWEKFFQQRGKTAFEWYGTYLELCEVLHKYIKPKEKVLVIGCGNSELSEQLYDVGYQDIVNIDISEVVIKQMKERNGSRRPHMSFLKMDMTQLEFPDATFQVVLDKGTLDAVLTDEEEVTLRQVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSREGWMVRAHQVASSQDRVSEAEPRFSLPVFAFVMTKFRPVPGSALQIFELCTQEQGKPVRLESADQLAEAVRERQYYAWLCSQLRRKAGLGSVSLDLCSGDTGEPRYTLHVVDNPAVKPSRDNHFAIFIIPQGRETEWLFGMEEGRKQLAASAGFRRLVTVALHRGQRYAGMESIQAELSARVMELAPAGLPPQQQVPFLSVGGDIGVRTVQHQDHSALSGDYVIEDVQGEDRWYFRRLIFLSNRNVVQSEARLLKDTSHRAQKKRKKDRKKQRPADTSEDFPPAPGQSIDKSYLCCEHHKAMVAGLALLRNPELLLETPLTLLVVGLGGGSLPLFVHDHFPKSRIDAVEIDPTMLEVATQWFGFSQSDRMKVHIADGLDYITSLAGEAPPHYDVIMFDVDSKDPTLGMSCPPPAFVDQVFLQKVKSILCHDGVFILNLVCRDVRLKDSVLAGLKAAFPLLYVRRIEGEVNEILFCQLHPEQKLATPELLEMAQVLERTLRKPGQGWDDTYVLSDMLKTVKIV
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation (By similarity). Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2' (By similarity). Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55' (By similarity). Has no activity towards core histones H2A, H2B, H3 and H4 (By similarity). {ECO:0000250|UniProtKB:Q8N6R0}.
uniprot
proteins
mass_dalton
78757
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27659353
uniprot
proteins
pubmed
29408807
uniprot
proteins
sequence_length
698
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27659353}. Nucleus {ECO:0000269|PubMed:27659353}. Mitochondrion {ECO:0000269|PubMed:27659353}.
uniprot
proteins