Plp1
entrez
24943
canonical
uniprot
P60203
canonical
ensembl
ENSRNOG00000002419
resolver
ensembl
ENSRNOG00055025336
resolver
ensembl
ENSRNOG00060017626
resolver
ensembl
ENSRNOG00065026297
resolver
ensp
ENSRNOP00000003283
resolver
ensp
ENSRNOP00000106004
resolver
ensp
ENSRNOP00055035715
resolver
ensp
ENSRNOP00060024414
resolver
ensp
ENSRNOP00065037260
resolver
enst
ENSRNOT00000126862
resolver
enst
ENSRNOT00055043728
resolver
enst
ENSRNOT00060030251
resolver
enst
ENSRNOT00065045449
resolver
genesymbol
Plp1
resolver
genesymbol_syn
Plp
resolver
uniprot
A0A097BVK2
resolver
uniprot
P04400
resolver
uniprot
P06905
resolver
uniprot
Q561K5
resolver
uniprot_entry
A0A097BVK2_RAT
resolver
uniprot_entry
MYPR_RAT
resolver
uniprot_sec
P04400
resolver
uniprot_sec
P06905
resolver
uniprot_sec
Q561K5
resolver
amino_acid_sequence
MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Plp1 are the cause of the dysmyelinating disease MD.
uniprot
proteins
function
FUNCTION: This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
uniprot
proteins
mass_dalton
30077
uniprot
proteins
protein_family
Myelin proteolipid protein family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1689377
uniprot
proteins
pubmed
1702593
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2410294
uniprot
proteins
pubmed
2414013
uniprot
proteins
pubmed
2479544
uniprot
proteins
sequence_length
277
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Myelin membrane {ECO:0000250}. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 10..36; /note="Helical; Name=1"; /evidence="ECO:0000305"; TRANSMEM 64..88; /note="Helical; Name=2"; /evidence="ECO:0000305"; TRANSMEM 152..177; /note="Helical; Name=3"; /evidence="ECO:0000305"; TRANSMEM 234..260; /note="Helical; Name=4"; /evidence="ECO:0000305
uniprot
proteins