Bcl11a
entrez
14025
canonical
uniprot
Q9QYE3
canonical
ensembl
ENSMUSG00000000861
resolver
ensp
ENSMUSP00000000881
resolver
ensp
ENSMUSP00000105140
resolver
ensp
ENSMUSP00000105142
resolver
ensp
ENSMUSP00000112948
resolver
ensp
ENSMUSP00000178284
resolver
genesymbol
Bcl11a
resolver
genesymbol_syn
Ctip1
resolver
genesymbol_syn
Evi9
resolver
genesymbol_syn
Kiaa1809
resolver
uniprot
Q3TP99
resolver
uniprot
Q3US10
resolver
uniprot
Q5STS9
resolver
uniprot
Q80T89
resolver
uniprot
Q8BLC7
resolver
uniprot
Q8BLR4
resolver
uniprot
Q8BWX3
resolver
uniprot
Q921V4
resolver
uniprot
Q9D0V2
resolver
uniprot
Q9JIT4
resolver
uniprot
Q9JLK8
resolver
uniprot
Q9JLK9
resolver
uniprot_entry
BC11A_MOUSE
resolver
uniprot_entry
Q3TP99_MOUSE
resolver
uniprot_entry
Q3US10_MOUSE
resolver
uniprot_sec
Q5STS9
resolver
uniprot_sec
Q80T89
resolver
uniprot_sec
Q8BLC7
resolver
uniprot_sec
Q8BLR4
resolver
uniprot_sec
Q8BWX3
resolver
uniprot_sec
Q921V4
resolver
uniprot_sec
Q9D0V2
resolver
uniprot_sec
Q9JIT4
resolver
uniprot_sec
Q9JLK8
resolver
uniprot_sec
Q9JLK9
resolver
amino_acid_sequence
MSRRKQGKPQHLSKREFSPEPLEAILTDDEPDHGPLGAPEGDHDLLTCGQCQMNFPLGDILIFIEHKRKQCNGSLCLEKGVDKPPSPSPIEMKKASNPVEVGIQVTPEDDDCLSTSSRGICPKQEHIADKLLHWRGLSSPRSAHGALIPTPGMSAEYAPQGICKDEPSSYTCTTCKQPFTSAWFLLQHAQNTHGLRIYLESEHGSPLTPRVGIPSGLGAECPSQPPLHGIHIADNNPFNLLRIPGSVSREASGLAEGRFPPTPPLFSPPPRHHLDPHRIERLGAEEMALATHHPSAFDRVLRLNPMAMEPPAMDFSRRLRELAGNTSSPPLSPGRPSPMQRLLQPFQPGSKPPFLATPPLPPLQSAPPPSQPPVKSKSCEFCGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTHMHKSSPMTVKSDDGLSTASSPEPGTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEEEEEEEEEEELTESERVDYGFGLSLEAARHHENSSRGAVVGVGDEGRALPDVMQGMVLSSMQHFSEAFHQVLGEKHKRSHLAEAEGHRDTCDEDSVAGESDRIDDGTVNGRGCSPGESASGGLSKKLLLGSPSSLSPFSKRIKLEKEFDLPPAAMPNTENVYSQWLAGYAASRQLKDPFLTFGDSRQSPFASSSEHSSENGSLRFSTPPGELDGGISGRSGTGSGGSTPHISGPGPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQVGKDVYKCEICKMPFSVYSTLEKHMKKWHSDRVLNNDIKTE
uniprot
proteins
function
FUNCTION: Transcription factor (By similarity). Associated with the BAF SWI/SNF chromatin remodeling complex (PubMed:23644491). Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes (By similarity). Involved in brain development (By similarity). May play a role in hematopoiesis (PubMed:10757802). Essential factor in lymphopoiesis, required for B-cell formation in fetal liver (PubMed:12717432). May function as a modulator of the transcriptional repression activity of NR2F2 (PubMed:10744719). {ECO:0000250|UniProtKB:Q9H165, ECO:0000269|PubMed:10744719, ECO:0000269|PubMed:10757802, ECO:0000269|PubMed:12717432, ECO:0000269|PubMed:23644491}.
uniprot
proteins
mass_dalton
91197
uniprot
proteins
mutagenesis
MUTAGEN 123; /note="K->R: No effect on sumoylation."; /evidence="ECO:0000269|PubMed:18681895"; MUTAGEN 637; /note="K->R: Abolishes sumoylation. No effect on nuclear body location."; /evidence="ECO:0000269|PubMed:18681895
uniprot
proteins
post_translational_modification
PTM: Sumoylated with SUMO1. {ECO:0000269|PubMed:18681895}.
uniprot
proteins
pubmed
10744719
uniprot
proteins
pubmed
10757802
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
12717432
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18681895
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21750661
uniprot
proteins
pubmed
23644491
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
27453576
uniprot
proteins
sequence_length
835
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18681895}. Nucleus {ECO:0000269|PubMed:18681895}. Note=Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.
uniprot
proteins