Lin54
entrez
305171
canonical
uniprot
Q641Z1
canonical
ensembl
ENSRNOG00000002203
resolver
ensp
ENSRNOP00000083208
resolver
ensp
ENSRNOP00000096414
resolver
enst
ENSRNOT00000102075
resolver
enst
ENSRNOT00000119980
resolver
genesymbol
Lin54
resolver
uniprot
A0A8I6G8M1
resolver
uniprot
Q4FZV6
resolver
uniprot_entry
A0A8I6G8M1_RAT
resolver
uniprot_entry
LIN54_RAT
resolver
uniprot_sec
Q4FZV6
resolver
amino_acid_sequence
MEVVPAEVNSLLPDDIMDTAITLVDEDSIEAVIVSSPIPMETELEEIVSINSTGDSTATPISTEPITVYSNHTNQVAVNTTVSKADSNTTVKPAFPSGLQKLGAQTPVTISANQIILNKVSQTSDLKLGNQTLKPDGQKLILTTLGKSGSPIVLALPHSQLPQAQKVTAQAQPGDAKLPPQQIKVVTIGGRPEVKPAIGVSALTPGSQLINTTTQPSVLQTQQLKTVQIAKKPRTPTSGPVITKLIFAKPINSKAVTGQTTQASPPVVTGRVLSQSAPGTPSKTITISESGVIGSTLNSTTQTPNKIAISPLKSPNKTVKSAVQTITVGGMSTSQFKTIIPLAAAPNVQPIQVPGSKFHYVRLVTATTAGSSAPPVSQSPSVNTQPLQQAKPVVVNTTPVRMSVPFVQAQAVKQVVPKPINSTSQIVTTSQPQQRLIMPATPLPQIQPNLTNLPPGTVLAPAPGTGNVGYAVLPAQYVTQLQQSSYVSIAGNSNFTGTSGIQTQARVSFNGIIPSESASRPRKPCNCTKSLCLKLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKGCNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLSSQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAERMILEEFGRCLMSVINSAGKAKSDPCAMHC
uniprot
proteins
function
FUNCTION: Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner. Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA. {ECO:0000250|UniProtKB:Q6MZP7}.
uniprot
proteins
mass_dalton
79261
uniprot
proteins
protein_family
Lin-54 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
749
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins