Tmtc4
entrez
70551
canonical
uniprot
Q8BG19
canonical
ensembl
ENSMUSG00000041594
resolver
ensp
ENSMUSP00000046368
resolver
ensp
ENSMUSP00000116379
resolver
ensp
ENSMUSP00000121523
resolver
ensp
ENSMUSP00000238406
resolver
ensp
ENSMUSP00000238410
resolver
ensp
ENSMUSP00000238415
resolver
ensp
ENSMUSP00000238449
resolver
genesymbol
Tmtc4
resolver
uniprot
Q8BT03
resolver
uniprot
Q8C4D2
resolver
uniprot
Q8CAC3
resolver
uniprot
Q8K0I2
resolver
uniprot
Q9CS83
resolver
uniprot
Q9D5P3
resolver
uniprot_entry
TMTC4_MOUSE
resolver
uniprot_sec
Q8BT03
resolver
uniprot_sec
Q8C4D2
resolver
uniprot_sec
Q8CAC3
resolver
uniprot_sec
Q8K0I2
resolver
uniprot_sec
Q9CS83
resolver
uniprot_sec
Q9D5P3
resolver
amino_acid_sequence
MVELDADLDHIVPSVLPPFWAKLVVGFVSLLCFARSYDGDFVFDDSEAIVNNKDLQSDTPLGDLWHHDFWGSKLSSNTSHKSYRPLTVLTFRINYYLSGGFHPVGFHVVNILLHGSISILMLDVFSVLFGGLQYTGKGQRVHLAPRASLLATLLFAVHPVHTECVAGVVGRADLLCALFFLLSFLGYCQAFKETGNKEGTHSSTFWVLLSIFLGAVAMLCKEQGITVLGLNAVFDILVIGKLDILAAVRKVLHKDKSQENAGMFKNGGLLFRIALLTIGGTSMLYIRWKIMGTGPPAFTEVDNPASFADSMLVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLIGLIFQALCSEDSCKRRILTLGLGFLVIPFLPASNLFFRVGFVVAERVLYLPSAGYCVLLTFGFGALSRHTKKKKPVAAIILGILLINALRCVIRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAVGTKENYSLLRRKLEQTQKKDV
uniprot
proteins
ec_number
2.4.1.109
uniprot
proteins
function
FUNCTION: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. {ECO:0000250|UniProtKB:Q5T4D3}.
uniprot
proteins
mass_dalton
82963
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q5T4D3}.
uniprot
proteins
protein_family
TMTC family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
37943620
uniprot
proteins
sequence_length
741
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q5T4D3}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 111..131; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 147..166; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 167..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 199..219; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 355..375; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 383..403; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 413..433; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 442..462; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins