LIPI
entrez
149998
canonical
uniprot
Q6XZB0
canonical
ensembl
ENSG00000188992
resolver
ensp
ENSP00000383072
resolver
ensp
ENSP00000440381
resolver
ensp
ENSP00000482652
resolver
ensp
ENSP00000505323
resolver
ensp
ENSP00000505904
resolver
ensp
ENSP00000506458
resolver
enst
ENST00000400211
resolver
genesymbol
LIPI
resolver
genesymbol_syn
LPDL
resolver
hgnc
HGNC:18821
resolver
uniprot
G1JSG3
resolver
uniprot
G1JSG4
resolver
uniprot
G1JSG5
resolver
uniprot
G1JSG6
resolver
uniprot
G1JSG7
resolver
uniprot
G1JSG8
resolver
uniprot
G1JSG9
resolver
uniprot
H0Y3S0
resolver
uniprot_entry
H0Y3S0_HUMAN
resolver
uniprot_entry
LIPI_HUMAN
resolver
uniprot_sec
G1JSG3
resolver
uniprot_sec
G1JSG4
resolver
uniprot_sec
G1JSG5
resolver
uniprot_sec
G1JSG6
resolver
uniprot_sec
G1JSG7
resolver
uniprot_sec
G1JSG8
resolver
uniprot_sec
G1JSG9
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by sodium vanadate. {ECO:0000269|PubMed:12963729}.
uniprot
proteins
amino_acid_sequence
MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT
uniprot
proteins
ec_number
3.1.1.-
uniprot
proteins
function
FUNCTION: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). {ECO:0000269|PubMed:12963729}.
uniprot
proteins
mass_dalton
52922
uniprot
proteins
mutagenesis
MUTAGEN 159; /note="S->A: No activity."; /evidence="ECO:0000269|PubMed:12963729
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
Lipase family
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
12719377
uniprot
proteins
pubmed
12963729
uniprot
proteins
pubmed
21132378
uniprot
proteins
sequence_length
460
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:12963729}. Secreted {ECO:0000269|PubMed:12963729}. Note=May associate with lipid draft. {ECO:0000269|PubMed:12963729}.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane {ECO:0000269|PubMed:12963729}. Secreted {ECO:0000269|PubMed:12963729}. Note=May associate with lipid draft. {ECO:0000269|PubMed:12963729}.
uniprot
proteins