Sephs2
entrez
20768
canonical
uniprot
P97364
canonical
ensembl
ENSMUSG00000049091
resolver
ensp
ENSMUSP00000081009
resolver
genesymbol
Sephs2
resolver
genesymbol_syn
Sps2
resolver
uniprot
Q3TGI4
resolver
uniprot
Q80ZY9
resolver
uniprot_entry
SPS2_MOUSE
resolver
uniprot_sec
Q3TGI4
resolver
uniprot_sec
Q80ZY9
resolver
amino_acid_sequence
MAEAAAAGASGETMAALVAAEGSLGPAGWSAGRSFSNYRPFEPQTLGFSPSWRLTSFSGMKGUGCKVPQETLLKLLEGLTRPALQPPLTSGLVGGQEETVQEGGLSTRPGPGSAFPSLSIGMDSCVIPLRHGGLSLVQTTDFFYPLVEDPYMMGRIACANVLSDLYAMGITECDNMLMLLSVSQSMSEKEREKVTPLMIKGFRDAAEEGGTAVTGGQTVVNPWIIIGGVATVVCQQNEFIMPDSAVVGDVLVLTKPLGTQVAANAHQWLDNPEKWNKIKMVVSREEVELAYQEAMFNMATLNRTAAGLMHTFNAHAATDITGFGILGHSQNLAKQQKNEVSFVIHNLPIIAKMAAISKASGRFGLLQGTSAETSGGLLICLPREQAARFCSEIKSSKYGEGHQAWIVGIVEKGNRTARIIDKPRVIEVLPRGASAAAAAAPDNSNAASEPSS
uniprot
proteins
ec_number
2.7.9.3
uniprot
proteins
function
FUNCTION: Selenophosphate synthase that generates the selenium donor for selenocysteine biosynthesis by catalyzing formation of selenophosphate from selenide and ATP. {ECO:0000269|PubMed:10515607, ECO:0000269|PubMed:17194211, ECO:0000269|PubMed:17346238}.
uniprot
proteins
mass_dalton
47834
uniprot
proteins
post_translational_modification
PTM: Truncated SEPHS2 proteins produced by failed UGA/Sec decoding are ubiquitinated by the CRL2(KLHDC3) complex, which recognizes the glycine (Gly) at the C-terminus of truncated SEPHS2 proteins. {ECO:0000250|UniProtKB:Q99611}.
uniprot
proteins
protein_family
Class I subfamily
uniprot
proteins
protein_family
Selenophosphate synthase 1 family
uniprot
proteins
pubmed
10515607
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17194211
uniprot
proteins
pubmed
17346238
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7588067
uniprot
proteins
pubmed
8986768
uniprot
proteins
sequence_length
452
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q99611}.
uniprot
proteins