Dmtf1
entrez
114485
canonical
uniprot
Q66HG1
canonical
ensembl
ENSRNOG00000005908
resolver
ensembl
ENSRNOG00055019016
resolver
ensembl
ENSRNOG00060012746
resolver
ensembl
ENSRNOG00065018369
resolver
ensp
ENSRNOP00000007948
resolver
genesymbol
Dmtf1
resolver
uniprot
Q99MC8
resolver
uniprot_entry
DMTF1_RAT
resolver
uniprot_sec
Q99MC8
resolver
amino_acid_sequence
MSTVEEDSDTVTVETVNSVTFTQDTDGNLILHCPQNDPDEIDSEDSTEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDELSEGTVTQIQILQNDQLDEMSPLGTEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPVLLENKSGSGVPNSNCNSSVQHVQIRVARLEDNTAISPSPMAALQIPVQITHVSSTDSPAASVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTTSPTVTLAAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTADSDLHSSDFPEPPDALEADTFPDEIPRPKMTIQPSFNNAHVSKYSDQNSTELMNSVMVRTEEEIADTDLKQEPPSDLASAYVTEDLESPTIVHQVHQTIDDETILIVPSPHGFIQASDGIDAESVLPLTTLTDPIFQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH
uniprot
proteins
function
FUNCTION: Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest. Binds to the consensus sequence 5'-CCCG[GT]ATGT-3'. {ECO:0000250}.
uniprot
proteins
mass_dalton
84452
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by the cyclin-D2/CDK4, cyclin-D3/CDK4 and cyclin-D2/CDK6 complexes and to a lesser extent by the cyclin-D1/CDK4 complex. {ECO:0000250}.
uniprot
proteins
protein_family
DMTF1 family
uniprot
proteins
pubmed
11707776
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
760
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
uniprot
proteins