Nog
entrez
18121
canonical
uniprot
P97466
canonical
ensembl
ENSMUSG00000048616
resolver
ensp
ENSMUSP00000061427
resolver
enst
ENSMUST00000061728
resolver
genesymbol
Nog
resolver
uniprot
A2RTJ4
resolver
uniprot_entry
A2RTJ4_MOUSE
resolver
uniprot_entry
NOGG_MOUSE
resolver
amino_acid_sequence
MERCPSLGVTLYALVVVLGLRAAPAGGQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGPAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
uniprot
proteins
function
FUNCTION: Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (PubMed:9585504, PubMed:9603738). Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity). {ECO:0000250|UniProtKB:Q13253, ECO:0000269|PubMed:9585504, ECO:0000269|PubMed:9603738}.
uniprot
proteins
mass_dalton
25770
uniprot
proteins
protein_family
Noggin family
uniprot
proteins
pubmed
9585504
uniprot
proteins
pubmed
9603738
uniprot
proteins
sequence_length
232
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins