Nfam1
entrez
74039
canonical
uniprot
Q8R4V1
canonical
ensembl
ENSMUSG00000058099
resolver
ensp
ENSMUSP00000023076
resolver
ensp
ENSMUSP00000105129
resolver
ensp
ENSMUSP00000154945
resolver
genesymbol
Nfam1
resolver
genesymbol_syn
Cnaip
resolver
uniprot
Q3TCT5
resolver
uniprot
Q3UAX8
resolver
uniprot
Q9D5Z3
resolver
uniprot_entry
NFAM1_MOUSE
resolver
uniprot_entry
Q3TCT5_MOUSE
resolver
uniprot_sec
Q3UAX8
resolver
uniprot_sec
Q9D5Z3
resolver
amino_acid_sequence
MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL
uniprot
proteins
function
FUNCTION: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF promoters (By similarity). May be involved in the regulation of B-cell, but not T-cell, development. {ECO:0000250}.
uniprot
proteins
mass_dalton
29988
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:15143214}.
uniprot
proteins
pubmed
15143214
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
sequence_length
264
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Partially recruited to lipid rafts upon BCR stimulation. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 160..180; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins