TES
entrez
26136
canonical
uniprot
Q9UGI8
canonical
ensembl
ENSG00000135269
resolver
ensp
ENSP00000350937
resolver
ensp
ENSP00000377121
resolver
genesymbol
TES
resolver
hgnc
HGNC:14620
resolver
uniprot
A4D0U6
resolver
uniprot
Q9GZQ1
resolver
uniprot
Q9HAJ9
resolver
uniprot_entry
TES_HUMAN
resolver
uniprot_sec
A4D0U6
resolver
uniprot_sec
Q9GZQ1
resolver
uniprot_sec
Q9HAJ9
resolver
amino_acid_sequence
MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS
uniprot
proteins
function
FUNCTION: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. {ECO:0000269|PubMed:11420696, ECO:0000269|PubMed:12571287, ECO:0000269|PubMed:12695497}.
uniprot
proteins
mass_dalton
47996
uniprot
proteins
mutagenesis
MUTAGEN 328; /note="C->A: Abolishes interaction with ACTL7A."; /evidence="ECO:0000269|PubMed:21278383"; MUTAGEN 391; /note="C->A: Abolishes localization at focal adhesions."; /evidence="ECO:0000269|PubMed:12695497
uniprot
proteins
protein_family
Prickle / espinas / testin family
uniprot
proteins
pubmed
10950921
uniprot
proteins
pubmed
11420696
uniprot
proteins
pubmed
12571287
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12695497
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18158903
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21278383
uniprot
proteins
pubmed
23145062
uniprot
proteins
sequence_length
421
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
uniprot
proteins