Tle5
entrez
29466
canonical
uniprot
P63003
canonical
ensembl
ENSRNOG00000052025
resolver
ensembl
ENSRNOG00055033151
resolver
ensembl
ENSRNOG00060029904
resolver
ensembl
ENSRNOG00065021444
resolver
ensp
ENSRNOP00000079330
resolver
ensp
ENSRNOP00000092723
resolver
ensp
ENSRNOP00000097044
resolver
ensp
ENSRNOP00055047234
resolver
ensp
ENSRNOP00060043294
resolver
ensp
ENSRNOP00065029428
resolver
enst
ENSRNOT00000098364
resolver
enst
ENSRNOT00000100632
resolver
enst
ENSRNOT00055057299
resolver
enst
ENSRNOT00060052056
resolver
enst
ENSRNOT00065036520
resolver
genesymbol
Tle5
resolver
genesymbol_syn
Aes
resolver
genesymbol_syn
Esp1
resolver
genesymbol_syn
Grg
resolver
genesymbol_syn
Grg5
resolver
uniprot
A0A8I6ARX3
resolver
uniprot
A0A8I6G347
resolver
uniprot
Q06195
resolver
uniprot
Q3MIF3
resolver
uniprot_entry
A0A8I6ARX3_RAT
resolver
uniprot_entry
A0A8I6G347_RAT
resolver
uniprot_entry
TLE5_RAT
resolver
uniprot_sec
Q06195
resolver
uniprot_sec
Q3MIF3
resolver
amino_acid_sequence
MMFPQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAHQLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSLSALGSQTHLSKEDKNGHDGDTHQEDDGEKSD
uniprot
proteins
function
FUNCTION: Transcriptional corepressor. Acts as a dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
22000
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by XIAP/BIRC4. {ECO:0000250}.
uniprot
proteins
protein_family
WD repeat Groucho/TLE family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8245004
uniprot
proteins
sequence_length
197
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins