SDR16C5
entrez
195814
canonical
uniprot
Q8N3Y7
canonical
ensembl
ENSG00000170786
resolver
ensp
ENSP00000307607
resolver
ensp
ENSP00000379947
resolver
ensp
ENSP00000431010
resolver
enst
ENST00000522671
resolver
genesymbol
SDR16C5
resolver
genesymbol_syn
RDHE2
resolver
hgnc
HGNC:30311
resolver
uniprot
B3KT84
resolver
uniprot
B4DGK2
resolver
uniprot
G3V145
resolver
uniprot
Q330K3
resolver
uniprot
Q8TDV9
resolver
uniprot
Q96LX1
resolver
uniprot_entry
B3KT84_HUMAN
resolver
uniprot_entry
G3V145_HUMAN
resolver
uniprot_entry
RDHE2_HUMAN
resolver
uniprot_sec
B4DGK2
resolver
uniprot_sec
Q330K3
resolver
uniprot_sec
Q8TDV9
resolver
uniprot_sec
Q96LX1
resolver
amino_acid_sequence
MSFNLQSSKKLFIFLGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKTGMFEGCTTGCPSLLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKSFLPLKTGLLIADYLGILHAMDGFVDQKKKL
uniprot
proteins
ec_number
1.1.1.105
uniprot
proteins
function
FUNCTION: Oxidoreductase with strong preference for NAD (PubMed:18926804). Active in both the oxidative and reductive directions (PubMed:18926804). Oxidizes all-trans-retinol in all-trans-retinaldehyde (PubMed:18926804). No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH (PubMed:18926804). {ECO:0000269|PubMed:18926804}.
uniprot
proteins
mass_dalton
34095
uniprot
proteins
pathway_participation
PATHWAY: Cofactor metabolism; retinol metabolism. {ECO:0000269|PubMed:18926804}.
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
12372410
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15457346
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18926804
uniprot
proteins
sequence_length
309
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18926804}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 270..290; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins