DOLPP1
entrez
57171
canonical
uniprot
Q86YN1
canonical
ensembl
ENSG00000167130
resolver
ensp
ENSP00000361625
resolver
ensp
ENSP00000384043
resolver
genesymbol
DOLPP1
resolver
genesymbol_syn
LSFR2
resolver
hgnc
HGNC:29565
resolver
uniprot
A8K3U8
resolver
uniprot
B0QZG4
resolver
uniprot
Q96GF8
resolver
uniprot
Q9Y3G1
resolver
uniprot_entry
DOPP1_HUMAN
resolver
uniprot_sec
A8K3U8
resolver
uniprot_sec
B0QZG4
resolver
uniprot_sec
Q96GF8
resolver
uniprot_sec
Q9Y3G1
resolver
amino_acid_sequence
MAADGQCSLPASWRPVTLTHVEYPAGDLSGHLLAYLSLSPVFVIVGFVTLIIFKRELHTISFLGGLALNEGVNWLIKNVIQEPRPCGGPHTAVGTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSLGLLAVAFLVSYSRVYLLYHTWSQVLYGGIAGGLMAIAWFIFTQEVLTPLFPRIAAWPVSEFFLIRDTSLIPNVLWFEYTVTRAEARNRQRKLGTKLQ
uniprot
proteins
ec_number
3.6.1.43
uniprot
proteins
function
FUNCTION: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity). {ECO:0000250|UniProtKB:Q9JMF7}.
uniprot
proteins
mass_dalton
27031
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.
uniprot
proteins
protein_family
Dolichyldiphosphatase family
uniprot
proteins
pubmed
10369878
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
238
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 33..53; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 130..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 162..182; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins