Plvap
entrez
56765
canonical
uniprot
Q9WV78
canonical
ensembl
ENSRNOG00000017676
resolver
ensembl
ENSRNOG00055010629
resolver
ensembl
ENSRNOG00055022055
resolver
ensembl
ENSRNOG00060011347
resolver
ensembl
ENSRNOG00065020573
resolver
ensp
ENSRNOP00000023927
resolver
ensp
ENSRNOP00055014485
resolver
ensp
ENSRNOP00055030937
resolver
ensp
ENSRNOP00060015014
resolver
ensp
ENSRNOP00065027973
resolver
enst
ENSRNOT00055018002
resolver
enst
ENSRNOT00055037896
resolver
enst
ENSRNOT00060019194
resolver
enst
ENSRNOT00065034832
resolver
genesymbol
Plvap
resolver
genesymbol_syn
Pv1
resolver
uniprot_entry
PLVAP_RAT
resolver
amino_acid_sequence
MGLSMDRSPYSRTGDRDRGCWYYLRYFFLFVSLIQFLIILGLVLFMIYGNVHATTESSLRATEIRADNLYSQVVGLSAAQANLSKQLNISTLVKDTVMQQLLTTRREVERINASFRQCQGDLITYINYNRFIAAIILSEKQCQEQLKEGNKTCEALLFKLGEKVKTLEMEVVKEKAVCSKDKDSLLAGKRQAEMQQEACGKAREQQKQDQQVTEEQLRKVQSLCLPLDQEKFQADVLNVWRDSLVYRSLDNIGYHYSLMPEFSSLRRTCESLPGIMTTKVEELARGLRAGIERVTRENGELRRQKLELERAIQGEREARTRAGTEAQARETQLRTECARQTQLALEEKAALRTQRDDLERQLEARKRELEQLRTEVDVRISALDTCVKAKSLPAIQPRLPGPPPNPPPIDPASLEEFKKRILESQRPPLVNPAVPPSG
uniprot
proteins
function
FUNCTION: Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development. {ECO:0000250|UniProtKB:Q91VC4}.
uniprot
proteins
mass_dalton
50033
uniprot
proteins
pubmed
10366592
uniprot
proteins
pubmed
10557298
uniprot
proteins
pubmed
12475376
uniprot
proteins
pubmed
14630628
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15640522
uniprot
proteins
sequence_length
438
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10366592, ECO:0000269|PubMed:10557298}; Single-pass type II membrane protein {ECO:0000255}. Membrane, caveola {ECO:0000269|PubMed:10366592, ECO:0000269|PubMed:10557298}; Single-pass type II membrane protein {ECO:0000255}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:15640522}. Note=Membrane-associated protein of caveolae (PubMed:10366592). Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels (PubMed:10557298). Also colocalized with CAV1 in perinuclear region (PubMed:15640522). {ECO:0000269|PubMed:10366592, ECO:0000269|PubMed:10557298, ECO:0000269|PubMed:15640522}.
uniprot
proteins
transmembrane_region
TRANSMEM 27..47; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins