LIMCH1
entrez
22998
canonical
uniprot
Q9UPQ0
canonical
ensembl
ENSG00000064042
resolver
ensp
ENSP00000316891
resolver
ensp
ENSP00000371172
resolver
ensp
ENSP00000379840
resolver
ensp
ENSP00000421242
resolver
ensp
ENSP00000421656
resolver
ensp
ENSP00000422864
resolver
ensp
ENSP00000424437
resolver
ensp
ENSP00000424645
resolver
ensp
ENSP00000424825
resolver
ensp
ENSP00000425222
resolver
ensp
ENSP00000425631
resolver
ensp
ENSP00000427045
resolver
ensp
ENSP00000525882
resolver
ensp
ENSP00000525883
resolver
ensp
ENSP00000525885
resolver
ensp
ENSP00000614112
resolver
ensp
ENSP00000614114
resolver
ensp
ENSP00000614115
resolver
ensp
ENSP00000614135
resolver
ensp
ENSP00000614138
resolver
ensp
ENSP00000614139
resolver
ensp
ENSP00000614141
resolver
ensp
ENSP00000614146
resolver
ensp
ENSP00000614150
resolver
ensp
ENSP00000614174
resolver
ensp
ENSP00000614182
resolver
enst
ENST00000503057
resolver
enst
ENST00000509277
resolver
enst
ENST00000512632
resolver
enst
ENST00000944055
resolver
genesymbol
LIMCH1
resolver
genesymbol_syn
KIAA1102
resolver
hgnc
HGNC:29191
resolver
uniprot
A8MXC3
resolver
uniprot
B7Z2J4
resolver
uniprot
B7Z656
resolver
uniprot
D6RD46
resolver
uniprot
E9PDJ9
resolver
uniprot
E9PHM7
resolver
uniprot
G5EA03
resolver
uniprot
Q503B5
resolver
uniprot
Q5CZB1
resolver
uniprot
Q5CZB6
resolver
uniprot
Q5H9S8
resolver
uniprot
Q68E07
resolver
uniprot
Q6PJ44
resolver
uniprot
Q7Z3G5
resolver
uniprot
Q8N3S9
resolver
uniprot
Q8N6M2
resolver
uniprot_entry
B7Z2J4_HUMAN
resolver
uniprot_entry
B7Z656_HUMAN
resolver
uniprot_entry
D6RD46_HUMAN
resolver
uniprot_entry
E9PDJ9_HUMAN
resolver
uniprot_entry
G5EA03_HUMAN
resolver
uniprot_entry
LIMC1_HUMAN
resolver
uniprot_sec
A8MXC3
resolver
uniprot_sec
E9PHM7
resolver
uniprot_sec
Q503B5
resolver
uniprot_sec
Q5CZB1
resolver
uniprot_sec
Q5CZB6
resolver
uniprot_sec
Q5H9S8
resolver
uniprot_sec
Q68E07
resolver
uniprot_sec
Q6PJ44
resolver
uniprot_sec
Q7Z3G5
resolver
uniprot_sec
Q8N3S9
resolver
uniprot_sec
Q8N6M2
resolver
amino_acid_sequence
MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
uniprot
proteins
function
FUNCTION: Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. {ECO:0000269|PubMed:28228547}.
uniprot
proteins
mass_dalton
121867
uniprot
proteins
protein_family
LIMCH1 family
uniprot
proteins
pubmed
10470851
uniprot
proteins
pubmed
12168954
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28228547
uniprot
proteins
sequence_length
1083
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:28228547}.
uniprot
proteins