Map1s
entrez
290640
canonical
uniprot
P0C5W1
canonical
ensembl
ENSRNOG00000018781
resolver
ensp
ENSRNOP00000025385
resolver
genesymbol
Map1s
resolver
genesymbol_syn
Mtap1s
resolver
uniprot
B5DFH2
resolver
uniprot_entry
B5DFH2_RAT
resolver
uniprot_entry
MAP1S_RAT
resolver
amino_acid_sequence
MAAVMAAPEPAEAPSSLLLLVVGGECGCPGLLAYVLEELERGVRSWEDVDPDVCSLDEQLKAFVSRHSATFSSIVKGQRSLHHRGETLETLVLLNPSDKSLCDELRNLLMDPAPHKLLVLAGPCLEETGELLLQTGGFSAHHFLQVLGDKEVQDALASAPAAPALTVSCPTFGDWALLGPAPGLRLRLNPPARLPSSEGLRAFLEYVAESLEPPSPFELLEPPATGGFLRLARPCCYVFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHAGADSLPGLNSLLRRKLAEREAAAGPQGQHEERLRRLLSPALGVVFLNAREAGSRLRGGEDEAVCARSLLRSLGIVPLPLQRGPQPSCPTVLFEKLGVGRLELFVLHPPPGDPAAPACALLVWQPAAPGDKVVRVLFPGRTPPARLLDGLQRLQHLPCLRRPVVTTQDLEVPSRANSQDSLASRDSTRKEPVRGTVGATSRSAVRREPALATRDQKKDTKPGPTRSTVRDVRRSGPGVVTTKPRVSQNGPRAPVPAAPPAAPAPEFPGEAENIVESERPPAPSPTLSPAQSPPPTAPGNSPERLSLSPLRPEPAPDASPSATTPTLTTPSLPAELGSPHSTEVDESLSVSFEQVLPAGDAGLSLPLRLARRSTSPHDVDLCLVSPCEFSHRKPPPPASPGSSDSSARSQERPPETPPTSVSESLPTLSDSDPVPVADSDDDAGSESAARDPLPTPRVPPPLPDAPGICMVDPEALPPRARQPLSTANSSRGRKAPARPSSASAAPRAATVAAKTKGPVGDRSRPLSARSEPADKPGRVPLTRKPSVPKTVPKMASATRNSSGPSSRPAPLAAGSPVYLDLAYLPGGGAGHLDQNFFLRVRALCYVISGQGQRQEEGLRGVLDALLAGKRQWDLDLQVTLIPTFDSAVMHRWYEETHEQHQALGIRVLGSGSLVSMQDEAFPACKVEF
uniprot
proteins
function
FUNCTION: Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
102806
uniprot
proteins
protein_family
MAP1A/MAP1B/MAP1S family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
17658481
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
972
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17658481}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17658481}. Note=Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules (By similarity). Detected in filopodia-like protrusions and synapses. {ECO:0000250}.
uniprot
proteins