CHPT1
entrez
56994
canonical
uniprot
Q8WUD6
canonical
ensembl
ENSG00000111666
resolver
ensp
ENSP00000229266
resolver
ensp
ENSP00000538562
resolver
genesymbol
CHPT1
resolver
genesymbol_syn
CPT1
resolver
hgnc
HGNC:17852
resolver
uniprot
B3KQM2
resolver
uniprot
Q7Z7H0
resolver
uniprot
Q7Z7H1
resolver
uniprot
Q7Z7H2
resolver
uniprot
Q8IWQ4
resolver
uniprot
Q8IWQ5
resolver
uniprot
Q8WYI4
resolver
uniprot
Q9NRQ6
resolver
uniprot
Q9NRQ7
resolver
uniprot
Q9Y6M6
resolver
uniprot_entry
CHPT1_HUMAN
resolver
uniprot_sec
B3KQM2
resolver
uniprot_sec
Q7Z7H0
resolver
uniprot_sec
Q7Z7H1
resolver
uniprot_sec
Q7Z7H2
resolver
uniprot_sec
Q8IWQ4
resolver
uniprot_sec
Q8IWQ5
resolver
uniprot_sec
Q8WYI4
resolver
uniprot_sec
Q9NRQ6
resolver
uniprot_sec
Q9NRQ7
resolver
uniprot_sec
Q9Y6M6
resolver
amino_acid_sequence
MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSCSNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTKSELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKSHQNNMD
uniprot
proteins
ec_number
2.7.8.2
uniprot
proteins
function
FUNCTION: Catalyzes the final step of de novo phosphatidylcholine (PC) synthesis, i.e. the transfer of choline phosphate from CDP-choline to the free hydroxyl of a diacylglycerol (DAG), producing a PC. It thereby plays a central role in the formation and maintenance of vesicular membranes. {ECO:0000269|PubMed:10893425}.
uniprot
proteins
mass_dalton
45097
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 2/2. {ECO:0000269|PubMed:10893425}.
uniprot
proteins
protein_family
CDP-alcohol phosphatidyltransferase class-I family
uniprot
proteins
pubmed
10893425
uniprot
proteins
pubmed
12221122
uniprot
proteins
pubmed
12359261
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16292752
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
22814378
uniprot
proteins
sequence_length
406
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:12221122}; Multi-pass membrane protein {ECO:0000269|PubMed:12221122}.
uniprot
proteins
transmembrane_region
TRANSMEM 63..83; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 94..118; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 126..150; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 161..179; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 191..207; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 223..248; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 266..281; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 294..316; /note="Helical; Name=8"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 330..339; /note="Helical; Name=9"; /evidence="ECO:0000250|UniProtKB:Q4KLV1"; TRANSMEM 347..376; /note="Helical; Name=10"; /evidence="ECO:0000250|UniProtKB:Q4KLV1
uniprot
proteins