PSMA8
entrez
143471
canonical
uniprot
Q8TAA3
canonical
ensembl
ENSG00000154611
resolver
ensp
ENSP00000311121
resolver
ensp
ENSP00000345584
resolver
ensp
ENSP00000409284
resolver
ensp
ENSP00000482057
resolver
enst
ENST00000612461
resolver
genesymbol
PSMA8
resolver
genesymbol_syn
PSMA7L
resolver
hgnc
HGNC:22985
resolver
uniprot
A0A087WYS6
resolver
uniprot
B0YJ75
resolver
uniprot
Q4G1B8
resolver
uniprot
Q8IVP4
resolver
uniprot
Q8TA98
resolver
uniprot
Q8TAA2
resolver
uniprot_entry
A0A087WYS6_HUMAN
resolver
uniprot_entry
PSMA8_HUMAN
resolver
uniprot_entry
Q4G1B8_HUMAN
resolver
uniprot_sec
B0YJ75
resolver
uniprot_sec
Q8IVP4
resolver
uniprot_sec
Q8TA98
resolver
uniprot_sec
Q8TAA2
resolver
amino_acid_sequence
MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKEEAEKKKSKKSV
uniprot
proteins
function
FUNCTION: Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complex that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. {ECO:0000250|UniProtKB:Q9CWH6}.
uniprot
proteins
mass_dalton
28530
uniprot
proteins
protein_family
Peptidase T1A family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16177791
uniprot
proteins
sequence_length
256
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9CWH6}. Note=Localizes to the central region of the synaptonemal complex. {ECO:0000250|UniProtKB:Q9CWH6}.
uniprot
proteins