Syt5
entrez
54309
canonical
uniprot
P47861
canonical
ensembl
ENSRNOG00000018217
resolver
ensembl
ENSRNOG00055014573
resolver
ensembl
ENSRNOG00060027168
resolver
ensembl
ENSRNOG00065032466
resolver
ensp
ENSRNOP00000024547
resolver
ensp
ENSRNOP00055020425
resolver
ensp
ENSRNOP00060039205
resolver
ensp
ENSRNOP00065046009
resolver
enst
ENSRNOT00000024547
resolver
enst
ENSRNOT00055024992
resolver
enst
ENSRNOT00060047131
resolver
enst
ENSRNOT00065055865
resolver
genesymbol
Syt5
resolver
uniprot
Q56A28
resolver
uniprot_entry
SYT5_RAT
resolver
uniprot_sec
Q56A28
resolver
amino_acid_sequence
MFPEPPTPGSPAPETPPDSSRIRQGAVPAWVLATILLGSGLLVFSSCFCLYRKRCRRRMGKKSQAQAQVHLQEVKELGRSYIDKVQPEIEELDPSPSMPGQQVLDKHQLGRLQYSLDYDFQTGQLLVGILQAEGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGTAVGGAGLRHWADMLANPRRPIAQWHSLRPPDRARPIPAP
uniprot
proteins
function
FUNCTION: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface. {ECO:0000269|PubMed:12966166}.
uniprot
proteins
mass_dalton
43127
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
12966166
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7597049
uniprot
proteins
pubmed
7698322
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:12966166}; Single-pass membrane protein {ECO:0000269|PubMed:12966166}. Recycling endosome membrane {ECO:0000269|PubMed:12966166}; Single-pass membrane protein {ECO:0000269|PubMed:12966166}. Note=In mast cells, localizes to the endocytic recycling compartment.
uniprot
proteins
transmembrane_region
TRANSMEM 25..45; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins