SIGLEC5
entrez
8778
canonical
uniprot
O15389
canonical
ensembl
ENSG00000268500
resolver
ensp
ENSP00000507738
resolver
ensp
ENSP00000520903
resolver
ensp
ENSP00000679263
resolver
enst
ENST00000683636
resolver
enst
ENST00000850616
resolver
genesymbol
SIGLEC5
resolver
genesymbol_syn
CD33L2
resolver
genesymbol_syn
OBBP2
resolver
hgnc
HGNC:10874
resolver
uniprot
A0ABB0MVN2
resolver
uniprot_entry
A0ABB0MVN2_HUMAN
resolver
uniprot_entry
SIGL5_HUMAN
resolver
amino_acid_sequence
MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQSGSVLLLQGRSNLGTGVVPAALGGAGVMALLCICLCLIFFLIVKARRKQAAGRPEKMDDEDPIMGTITSGSRKKPWPDSPGDQASPPGDAPPLEEQKELHYASLSFSEMKSREPKDQEAPSTTEYSEIKTSK
uniprot
proteins
function
FUNCTION: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
uniprot
proteins
mass_dalton
60715
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
protein_family
SIGLEC (sialic acid binding Ig-like lectin) family
uniprot
proteins
pubmed
10428856
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18022638
uniprot
proteins
pubmed
9731071
uniprot
proteins
sequence_length
551
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 442..462; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins