S1PR3
entrez
1903
canonical
uniprot
Q99500
canonical
ensembl
ENSG00000213694
resolver
ensp
ENSP00000350878
resolver
ensp
ENSP00000365006
resolver
ensp
ENSP00000557848
resolver
ensp
ENSP00000557851
resolver
ensp
ENSP00000557853
resolver
ensp
ENSP00000638613
resolver
ensp
ENSP00000638614
resolver
ensp
ENSP00000638615
resolver
ensp
ENSP00000638616
resolver
enst
ENST00000358157
resolver
enst
ENST00000375846
resolver
enst
ENST00000887789
resolver
enst
ENST00000887792
resolver
enst
ENST00000887793
resolver
enst
ENST00000968554
resolver
enst
ENST00000968555
resolver
enst
ENST00000968556
resolver
enst
ENST00000968557
resolver
genesymbol
S1PR3
resolver
genesymbol_syn
C9orf108
resolver
genesymbol_syn
C9orf47
resolver
genesymbol_syn
EDG3
resolver
hgnc
HGNC:3167
resolver
uniprot
Q5SQD8
resolver
uniprot
Q7Z5I2
resolver
uniprot_entry
S1PR3_HUMAN
resolver
uniprot_sec
Q5SQD8
resolver
uniprot_sec
Q7Z5I2
resolver
amino_acid_sequence
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
uniprot
proteins
function
FUNCTION: Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. {ECO:0000269|PubMed:10617617}.
uniprot
proteins
mass_dalton
42250
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10383399
uniprot
proteins
pubmed
10617617
uniprot
proteins
pubmed
10908314
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
8878560
uniprot
proteins
pubmed
9409733
uniprot
proteins
sequence_length
378
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 41..65; /note="Helical; Name=1"; /evidence="ECO:0000250"; TRANSMEM 73..101; /note="Helical; Name=2"; /evidence="ECO:0000250"; TRANSMEM 116..134; /note="Helical; Name=3"; /evidence="ECO:0000250"; TRANSMEM 154..179; /note="Helical; Name=4"; /evidence="ECO:0000250"; TRANSMEM 196..216; /note="Helical; Name=5"; /evidence="ECO:0000250"; TRANSMEM 244..265; /note="Helical; Name=6"; /evidence="ECO:0000250"; TRANSMEM 282..302; /note="Helical; Name=7"; /evidence="ECO:0000250
uniprot
proteins