Map4k3
entrez
170920
canonical
uniprot
Q924I2
canonical
ensembl
ENSRNOG00000007172
resolver
ensembl
ENSRNOG00055021531
resolver
ensembl
ENSRNOG00065014551
resolver
ensp
ENSRNOP00000010366
resolver
ensp
ENSRNOP00000069683
resolver
ensp
ENSRNOP00000090754
resolver
ensp
ENSRNOP00000097492
resolver
ensp
ENSRNOP00055029984
resolver
ensp
ENSRNOP00065018854
resolver
enst
ENSRNOT00000084602
resolver
enst
ENSRNOT00000110847
resolver
enst
ENSRNOT00055036896
resolver
enst
ENSRNOT00065024162
resolver
genesymbol
Map4k3
resolver
uniprot
A0A0G2JVZ8
resolver
uniprot
A0A8I6AAR5
resolver
uniprot_entry
A0A0G2JVZ8_RAT
resolver
uniprot_entry
A0A8I6AAR5_RAT
resolver
uniprot_entry
M4K3_RAT
resolver
amino_acid_sequence
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHANIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIPSTSRNVREEKTRSEINFGQVKFDPPLRKETEPHHELDLQLEYGQGHQSNYFLGGNKSLLKSVEEELHQRGHVAHLEDDEGDDDDSKHSTLKAKVPPPLPPKPKSISIPQDTHSSEDSNQGTIKRCPSSGSPAKPSHVPPRPPPPRLPPQKPAVLGNGVSSFQLNGERDGSVHQQQSEQRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSVSGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIEFPMPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDNTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Activator of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. MAP4Ks act in parallel to and are partially redundant with STK3/MST2 and STK4/MST2 in the phosphorylation and activation of LATS1/2, and establish MAP4Ks as components of the expanded Hippo pathway. {ECO:0000250|UniProtKB:Q8IVH8}.
uniprot
proteins
mass_dalton
98679
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
STE Ser/Thr protein kinase family
uniprot
proteins
protein_family
STE20 subfamily
uniprot
proteins
pubmed
11384986
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
873
uniprot
proteins