RFNG
entrez
5986
canonical
uniprot
Q9Y644
canonical
ensembl
ENSG00000169733
resolver
ensp
ENSP00000307971
resolver
ensp
ENSP00000402931
resolver
enst
ENST00000310496
resolver
enst
ENST00000429557
resolver
genesymbol
RFNG
resolver
hgnc
HGNC:9974
resolver
uniprot
F5H3H7
resolver
uniprot
O00588
resolver
uniprot
Q8N9R1
resolver
uniprot_entry
F5H3H7_HUMAN
resolver
uniprot_entry
Q8N9R1_HUMAN
resolver
uniprot_entry
RFNG_HUMAN
resolver
uniprot_sec
O00588
resolver
amino_acid_sequence
MSRARGALCRACLALAAALAALLLLPLPLPRAPAPARTPAPAPRAPPSRPAAPSLRPDDVFIAVKTTRKNHGPRLRLLLRTWISRARQQTFIFTDGDDPELELQGGDRVINTNCSAVRTRQALCCKMSVEYDKFIESGRKWFCHVDDDNYVNARSLLHLLSSFSPSQDVYLGRPSLDHPIEATERVQGGRTVTTVKFWFATGGAGFCLSRGLALKMSPWASLGSFMSTAEQVRLPDDCTVGYIVEGLLGARLLHSPLFHSHLENLQRLPPDTLLQQVTLSHGGPENPHNVVNVAGGFSLHQDPTRFKSIHCLLYPDTDWCPRQKQGAPTSR
uniprot
proteins
ec_number
2.4.1.222
uniprot
proteins
function
FUNCTION: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in enhancement of NOTCH1 activation by DLL1 and JAG1. May be involved in limb formation and in neurogenesis. {ECO:0000250|UniProtKB:O09009, ECO:0000250|UniProtKB:O12972, ECO:0000250|UniProtKB:Q9R1U9}.
uniprot
proteins
mass_dalton
36424
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
10341080
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
9187150
uniprot
proteins
sequence_length
331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..29; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins