Sparc
entrez
20692
canonical
uniprot
P07214
canonical
ensembl
ENSMUSG00000018593
resolver
ensp
ENSMUSP00000018737
resolver
ensp
ENSMUSP00000104486
resolver
ensp
ENSMUSP00000151000
resolver
enst
ENSMUST00000018737
resolver
enst
ENSMUST00000108858
resolver
enst
ENSMUST00000214685
resolver
genesymbol
Sparc
resolver
uniprot
Q5NCU4
resolver
uniprot
Q5NCU5
resolver
uniprot_entry
Q5NCU4_MOUSE
resolver
uniprot_entry
Q5NCU5_MOUSE
resolver
uniprot_entry
SPRC_MOUSE
resolver
amino_acid_sequence
MRAWIFFLLCLAGRALAAPQQTEVAEEIVEEETVVEETGVPVGANPVQVEMGEFEDGAEETVEEVVADNPCQNHHCKHGKVCELDESNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDSELTEFPLRMRDWLKNVLVTLYERDEGNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALEEWAGCFGIKEQDINKDLVI
uniprot
proteins
function
FUNCTION: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
uniprot
proteins
mass_dalton
34450
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:3427055}.
uniprot
proteins
protein_family
SPARC family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
3109947
uniprot
proteins
pubmed
3165375
uniprot
proteins
pubmed
3410046
uniprot
proteins
pubmed
3427055
uniprot
proteins
pubmed
3755680
uniprot
proteins
sequence_length
302
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:3427055}. Note=In or around the basement membrane.
uniprot
proteins