Spin4
entrez
270624
canonical
uniprot
Q8K1L2
canonical
ensembl
ENSMUSG00000071722
resolver
ensp
ENSMUSP00000094095
resolver
enst
ENSMUST00000096367
resolver
genesymbol
Spin4
resolver
uniprot
Q8BXD0
resolver
uniprot_entry
SPIN4_MOUSE
resolver
uniprot_sec
Q8BXD0
resolver
amino_acid_sequence
MSPPTVPPTGVDGVSAYLMKKRHTHKKQRRKPTFLTHRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPSPRIDSRLADSLVGKAVGHVFEGEHGKKDEWKGMVLARAPIMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPAAEQEPGEVLDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVKTP
uniprot
proteins
function
FUNCTION: Binds to acetylated and methylated histones, including H3K4me3 and H4K20me3, probably acting as a histone reader that recognizes chromatin marks to mediate downstream cellular effects (By similarity). Promotes canonical WNT signaling, and is involved in the down-regulation of cell proliferation (PubMed:36927955). {ECO:0000250|UniProtKB:Q56A73, ECO:0000269|PubMed:36927955}.
uniprot
proteins
mass_dalton
28508
uniprot
proteins
protein_family
SPIN/STSY family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
36927955
uniprot
proteins
sequence_length
249
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q56A73}. Nucleus {ECO:0000250|UniProtKB:Q56A73}.
uniprot
proteins