Nudc
entrez
29648
canonical
uniprot
Q63525
canonical
ensembl
ENSRNOG00000051720
resolver
ensembl
ENSRNOG00055025715
resolver
ensembl
ENSRNOG00060030342
resolver
ensembl
ENSRNOG00065023395
resolver
ensp
ENSRNOP00000073414
resolver
ensp
ENSRNOP00055036316
resolver
ensp
ENSRNOP00060043855
resolver
ensp
ENSRNOP00065032537
resolver
enst
ENSRNOT00000079380
resolver
enst
ENSRNOT00055044409
resolver
enst
ENSRNOT00060052756
resolver
enst
ENSRNOT00065040035
resolver
genesymbol
Nudc
resolver
uniprot_entry
NUDC_RAT
resolver
amino_acid_sequence
MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFNHHNQLAQKARREKRARQETERREKAERAARLAKEAKAETPGPQIKELTDEEAERLQLEIDQKKDAENHEVQLKNGSLDSPGKQDAEEEEDEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFRVSFRLKGKDVVVDIQRRHLRVGLKGQAPVIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
uniprot
proteins
function
FUNCTION: Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (By similarity). Necessary for cytokinesis and cell proliferation (By similarity). {ECO:0000250|UniProtKB:O35685, ECO:0000250|UniProtKB:Q9Y266}.
uniprot
proteins
mass_dalton
38412
uniprot
proteins
post_translational_modification
PTM: Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-275 and Ser-327 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases (By similarity). {ECO:0000250|UniProtKB:Q9Y266}.
uniprot
proteins
protein_family
NudC family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7776977
uniprot
proteins
pubmed
9601647
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9Y266}. Midbody {ECO:0000250|UniProtKB:Q9Y266}. Note=A small proportion is nuclear, in a punctate pattern (By similarity). In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center (By similarity). Distributed throughout the cytoplasm of non-migrating cells (By similarity). {ECO:0000250|UniProtKB:Q9Y266}.
uniprot
proteins