Coasy
entrez
71743
canonical
uniprot
Q9DBL7
canonical
ensembl
ENSMUSG00000001755
resolver
ensp
ENSMUSP00000001806
resolver
ensp
ENSMUSP00000102929
resolver
enst
ENSMUST00000001806
resolver
enst
ENSMUST00000107308
resolver
genesymbol
Coasy
resolver
genesymbol_syn
Ukr1
resolver
uniprot
A2BFA8
resolver
uniprot
Q3TVZ2
resolver
uniprot
Q8K3Y4
resolver
uniprot_entry
COASY_MOUSE
resolver
uniprot_sec
A2BFA8
resolver
uniprot_sec
Q3TVZ2
resolver
uniprot_sec
Q8K3Y4
resolver
amino_acid_sequence
MAVFRSGLLVLTTPLATLAARLPPILTSASRLVNHTLYVHLQPGMNLGGPAQPQASPVQATFEVLDFITHLYTGADLHRHLDVRILLTNIQTKSTFLPVLSSVQNLAHPPEVVLTDFQTLDGSQYNPVKQQLERYATSCYSCSPQLASVLLYPDYGTGELPLEPPNALLPSTIRPASPVARSPRQPVRGYHRGAVGGTFDRLHNAHKVLLSVACVLAQEQLVVGVADKDLLKSKLLPELLQPYAERVEHLTEFLVDIKPSLTFELVPLLDPYGPAGSDPTLEFLVVSEETYRGGMAVNRFRLENGKEELALYQIQLLKDQSHNENEEDKVSSSSFRQRILGNLLQPPNERPELPSGLYVLGLTGISGSGKSSVAQRLKNLGAYIIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHKDGTINRKVLGSRVFGNKKQMKILTDIVWPVIAKLAREEMDVAVAKGKTLCVIDAAMLLEAGWQSMVHEVWTVVIPETEAVRRIVERDGLSEAAAQSRLQSQMSGQQLVEQSNVVLSTLWESHVTQSQVEKAWNLLQKRLPKAYQTRN
uniprot
proteins
ec_number
2.7.1.24
uniprot
proteins
ec_number
2.7.7.3
uniprot
proteins
function
FUNCTION: Bifunctional enzyme that catalyzes the fourth step of the coenzyme A biosynthetic pathway, the adenylation of 4'-phosphopantetheine, and the fifth step, the phosphorylation of dephospho-CoA to CoA. {ECO:0000269|PubMed:11980892}.
uniprot
proteins
mass_dalton
62023
uniprot
proteins
mutagenesis
MUTAGEN 203; /note="H->A: Phosphopantetheine adenylyltransferase activity abolished."; /evidence="ECO:0000269|PubMed:11980892
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. {ECO:0000269|PubMed:11980892}.; PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. {ECO:0000269|PubMed:11980892}.
uniprot
proteins
protein_family
Eukaryotic CoaD family
uniprot
proteins
pubmed
11980892
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
563
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q13057}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q13057}. Note=The protein is mainly cytosolic and active in the cytosol. Present in the mitochondrial matrix, probably anchored to the inner mitochondrial membrane. {ECO:0000250|UniProtKB:Q13057}.
uniprot
proteins