Hsd17b14
entrez
66065
canonical
uniprot
E9Q3D4
canonical
ensembl
ENSMUSG00000030825
resolver
ensp
ENSMUSP00000103381
resolver
ensp
ENSMUSP00000147715
resolver
enst
ENSMUST00000107752
resolver
genesymbol
Hsd17b14
resolver
genesymbol_syn
Dhrs10
resolver
genesymbol_syn
retSDR3
resolver
uniprot_entry
DHB14_MOUSE
resolver
amino_acid_sequence
MAAVTRYSGKVVVVTGGSRGIGAAIVRAFVDSGAQVVFCDKDEAGGRALEQELSGTVFIPGDVTQERDLQTLVSETLSRFGHLDCVVNNAGYHPPAQLPEETSAQGFRQLLEVNLLGTYTLIKLALPHLRKSRGNIINISSLVGAIGQSQALTYVATKGAVTAMTKALALDESRHGVRVNCISPGNIWTPLWEELAASTSDPRATILEGTLAQPLGRMGQPAEVAAAAVFLASEATFCTGLELLVTGGAELGYGRKASKSSLGEVPTLPPNVH
uniprot
proteins
ec_number
1.1.1.122
uniprot
proteins
function
FUNCTION: Catalyzes the NAD(+)-dependent oxidation of L-fucose, yielding L-fucono-1,5-lactone, which rapidly converts spontaneously to L-fucone-1,4-lactone. Can also act on D-arabinose and L-galactose, with lower catalytic efficiency. Does not use NADPH. May be the initial enzyme of the putative L-fucose degradation pathway in mammals. {ECO:0000250|UniProtKB:Q9BPX1}.
uniprot
proteins
mass_dalton
28579
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; L-fucose degradation. {ECO:0000250|UniProtKB:Q9MYP6}.
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BPX1}.
uniprot
proteins