H4C7
entrez
8369
canonical
uniprot
Q99525
canonical
ensembl
ENSG00000275663
resolver
ensp
ENSP00000477870
resolver
enst
ENST00000611444
resolver
genesymbol
H4C7
resolver
genesymbol_syn
H4/L
resolver
genesymbol_syn
H4FL
resolver
genesymbol_syn
HIST1H4G
resolver
hgnc
HGNC:4792
resolver
uniprot_entry
H4G_HUMAN
resolver
amino_acid_sequence
MSVRGKAGKGLGKGGAKCHRKVLSDNIQGITKCTIRRLARHGGVKRILGLIYEETRRVFKVFLENVIWYAVTNTEHAKRKTVTAMAVVYVLKRQGRTL
uniprot
proteins
function
FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11009
uniprot
proteins
protein_family
Histone H4 family
uniprot
proteins
pubmed
12408966
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9119399
uniprot
proteins
sequence_length
98
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
uniprot
proteins