Or5ar1
entrez
259017
canonical
uniprot
Q8VGS3
canonical
ensembl
ENSMUSG00000075208
resolver
ensp
ENSMUSP00000099694
resolver
ensp
ENSMUSP00000150622
resolver
enst
ENSMUST00000102634
resolver
enst
ENSMUST00000213515
resolver
genesymbol
Or5ar1
resolver
genesymbol_syn
Mor180-1
resolver
genesymbol_syn
Olfr1019
resolver
uniprot
Q149M3
resolver
uniprot_entry
O5AR1_MOUSE
resolver
uniprot_entry
Q149M3_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Copper binding enhances receptor activity in response to odorant binding. {ECO:0000269|PubMed:29659735}.
uniprot
proteins
amino_acid_sequence
MDKENHSVVTEFVFMGITQDPQLQIIFFVVFLLVYLVNVIGNVGMIILIITDSQLHTPMYFFLCNLSFVDLGYSSAIAPRMLADFLTKHKVISFSSCATQFAFFVGFVDAECYVLAAMAYDRFVAICRPLHYSTLMSKKVCLVLMLGSYFAGLVSLVAHTSLTFSLSYCGSNIINHFFCEIPPLLALSCSDTYISEILLFSLCGFIEFSTILIIFISYAFILIAIIRIRSAEGRLKAFSTCGSHLTGVTLFYGTVMFMYLRPTSSYSLDQDKWASVFYTIIIPMLNPLIYSLRNKDVKAAFKKLIGKKPQ
uniprot
proteins
function
FUNCTION: Olfactory receptor that is activated by the binding of organosulfur odorants with thioether groups such as (methylthio)methanethiol (MTMT). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (Probable). {ECO:0000269|PubMed:29659735, ECO:0000305}.
uniprot
proteins
mass_dalton
34860
uniprot
proteins
mutagenesis
MUTAGEN 203; /note="C->S: No receptor activity in response to MTMT binding, even in the presence of copper."; /evidence="ECO:0000269|PubMed:29659735"; MUTAGEN 256; /note="M->A: Decreased receptor activity in response to MTMT binding, even in the presence of copper."; /evidence="ECO:0000269|PubMed:29659735"; MUTAGEN 261; /note="R->W,H,A: No receptor activity in response to MTMT binding, even in the presence of copper."; /evidence="ECO:0000269|PubMed:29659735
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11802173
uniprot
proteins
pubmed
11875048
uniprot
proteins
pubmed
29659735
uniprot
proteins
sequence_length
310
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:29659735}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..46; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 55..75; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 134..154; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 197..217; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 238..258; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 272..292; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins