Two-component regulatory system
uniprot_keyword
KW-0902
canonical
name
Two-component regulatory system
uniprot
synonym
Phospho-relay system
uniprot
synonym
Phosphorelay system
uniprot
synonym
Two-component sensory transduction system
uniprot
synonym
Two-component signal transduction system
uniprot
synonym
Two-component system
uniprot
definition
Protein involved in a system responding to environmental changes characterized usually by a sensor kinase in the cell membrane that phosphorylates itself in response to a signal and a response regulator to which the phosphoryl group is transferred. The responder is typically a DNA-binding protein that regulates transcription. Several of these systems are quite complex, involving many proteins in a signaling cascade or contributing to several responses simultaneously. They are involved in a variety processes such as chemotaxis, osmoregulation, magnesium transport, pH tolerance, sporulation, or response of virulent species to host cell's environments.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords