Limch1
entrez
77569
canonical
uniprot
Q3UH68
canonical
ensembl
ENSMUSG00000037736
resolver
ensp
ENSMUSP00000043163
resolver
ensp
ENSMUSP00000098723
resolver
ensp
ENSMUSP00000112651
resolver
ensp
ENSMUSP00000112732
resolver
ensp
ENSMUSP00000113544
resolver
ensp
ENSMUSP00000158661
resolver
enst
ENSMUST00000117601
resolver
enst
ENSMUST00000118242
resolver
enst
ENSMUST00000238785
resolver
genesymbol
Limch1
resolver
genesymbol_syn
Kiaa1102
resolver
uniprot
A0A571BG24
resolver
uniprot
D3YU22
resolver
uniprot
D3Z589
resolver
uniprot
Q6DIC3
resolver
uniprot
Q80TK1
resolver
uniprot_entry
A0A571BG24_MOUSE
resolver
uniprot_entry
D3YU22_MOUSE
resolver
uniprot_entry
D3Z589_MOUSE
resolver
uniprot_entry
LIMC1_MOUSE
resolver
uniprot_sec
Q6DIC3
resolver
uniprot_sec
Q80TK1
resolver
amino_acid_sequence
MACPALGLEVLQPLQPEPPPEPAFAEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNTILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKNLDYSRKLKNVLVTIYWLGKAANSCASYGGTTLNLKEFEGLLAQMRKETDDIDSPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEFRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVLPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSASQDLIKKEEERKKMEKLMSGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNVSSFPNDPSPMKYLRQQSLPPPKFTATVETTIARTSVPESIASAGTGSPSKIITPNTVPMLTPRPYSQPKNSQEVLKTFKVDGKVSMNGEMAPGDEEGKEKEGPAAAAPGPSLTKSQMFEGVATVHDSPVQVKQGSNSIEINIKKPNSAPQELTAASEETESNGQEDEDGEERPGTGDLEPDSAEPQHFTTTVTRCSPTVALVEFSSNPQLKNEVPEQGQKKPEDEMSGKVELVLSQKVAKPKSPEPEATLTFPFLDKMPETNQLHLPNPSSQADSPSSEKSPGSTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTISSSSADQLSTSLSVTEGSGTRNKMDLENCPDKENERRQKTPFQENDGDSLLKTREGGLPEEQSLTPSPSANPEISVSKGIHQDPQLEAEAGAPHCGTNPQPAQDPPRNQQIPNPPTSTSEDVKPKTLALEKTINHQMESPGERRKSISGKKLCSSCGLTLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCTDCYMRSRSAGQPTTL
uniprot
proteins
function
FUNCTION: Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. {ECO:0000250|UniProtKB:Q9UPQ0}.
uniprot
proteins
mass_dalton
118196
uniprot
proteins
protein_family
LIMCH1 family
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1057
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:Q9UPQ0}.
uniprot
proteins