Acsl3
entrez
74205
canonical
uniprot
Q9CZW4
canonical
ensembl
ENSMUSG00000032883
resolver
ensp
ENSMUSP00000045291
resolver
ensp
ENSMUSP00000117952
resolver
ensp
ENSMUSP00000121695
resolver
ensp
ENSMUSP00000281328
resolver
ensp
ENSMUSP00000281335
resolver
ensp
ENSMUSP00000330863
resolver
ensp
ENSMUSP00000330864
resolver
enst
ENSMUST00000035779
resolver
enst
ENSMUST00000134566
resolver
enst
ENSMUST00000142704
resolver
genesymbol
Acsl3
resolver
genesymbol_syn
Acs3
resolver
genesymbol_syn
Facl3
resolver
uniprot
E9PUC2
resolver
uniprot
Q8K1J7
resolver
uniprot_entry
ACSL3_MOUSE
resolver
uniprot_entry
E9PUC2_MOUSE
resolver
uniprot_sec
Q8K1J7
resolver
amino_acid_sequence
MNNHVSSTPSTMKLKQTINPILLYFIHFIISLYTILTYIPFYFLCESKQEKPNQIKAKPVSSKPDSAYRSINSVDGLASVLYPGCDTLDKVFMYAKNKFKNKRLLGTREILNEEDEIQPNGKIFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVIVHTMAAVQALGVKANVEKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKTDFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFKGTWEELCNSSEMENEVLKVLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK
uniprot
proteins
ec_number
6.2.1.15
uniprot
proteins
ec_number
6.2.1.2
uniprot
proteins
ec_number
6.2.1.3
uniprot
proteins
function
FUNCTION: Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity). ACSL3 is required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (By similarity). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:O95573, ECO:0000250|UniProtKB:Q63151}.
uniprot
proteins
mass_dalton
80492
uniprot
proteins
protein_family
ATP-dependent AMP-binding enzyme family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
19737935
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
720
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 21..41; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins