MACIR
entrez
90355
canonical
uniprot
Q96GV9
canonical
ensembl
ENSG00000181751
resolver
ensp
ENSP00000326110
resolver
ensp
ENSP00000421270
resolver
ensp
ENSP00000422836
resolver
ensp
ENSP00000537696
resolver
ensp
ENSP00000537697
resolver
ensp
ENSP00000537698
resolver
ensp
ENSP00000537699
resolver
ensp
ENSP00000537700
resolver
ensp
ENSP00000581331
resolver
ensp
ENSP00000581332
resolver
ensp
ENSP00000581333
resolver
ensp
ENSP00000581334
resolver
ensp
ENSP00000581335
resolver
ensp
ENSP00000623471
resolver
ensp
ENSP00000623472
resolver
enst
ENST00000319933
resolver
enst
ENST00000510890
resolver
enst
ENST00000515669
resolver
enst
ENST00000867637
resolver
enst
ENST00000867638
resolver
enst
ENST00000867639
resolver
enst
ENST00000867640
resolver
enst
ENST00000867641
resolver
enst
ENST00000911272
resolver
enst
ENST00000911273
resolver
enst
ENST00000911274
resolver
enst
ENST00000911275
resolver
enst
ENST00000911276
resolver
enst
ENST00000953412
resolver
enst
ENST00000953413
resolver
genesymbol
MACIR
resolver
genesymbol_syn
C5orf30
resolver
hgnc
HGNC:25052
resolver
uniprot_entry
MACIR_HUMAN
resolver
amino_acid_sequence
MEVDINGESRSTLTTLPFPGAEANSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEESKAEAMPSLRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMIKEPADTEVLQYQLQHLTLRGDRVFARNNT
uniprot
proteins
function
FUNCTION: Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages (PubMed:30659109). The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis (PubMed:30659109). May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B (PubMed:22085962). May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells (PubMed:22085962). {ECO:0000269|PubMed:22085962, ECO:0000269|PubMed:30659109}.
uniprot
proteins
mass_dalton
23083
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000269|PubMed:18669648, ECO:0000269|PubMed:20068231, ECO:0000269|PubMed:21406692, ECO:0000269|PubMed:23186163, ECO:0000269|PubMed:30659109}.
uniprot
proteins
protein_family
UNC119-binding protein family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22085962
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26316022
uniprot
proteins
pubmed
30659109
uniprot
proteins
sequence_length
206
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22085962, ECO:0000269|PubMed:30659109}. Cell projection, cilium {ECO:0000269|PubMed:22085962}. Note=Localizes to the transition zone and proximal cilium in addition to being found throughout the cytoplasm. {ECO:0000269|PubMed:22085962}.
uniprot
proteins