Eipr1
entrez
362721
canonical
uniprot
Q5PPK9
canonical
ensembl
ENSRNOG00000009285
resolver
ensembl
ENSRNOG00055005748
resolver
ensembl
ENSRNOG00060009043
resolver
ensembl
ENSRNOG00065010559
resolver
ensp
ENSRNOP00000056930
resolver
ensp
ENSRNOP00055007123
resolver
ensp
ENSRNOP00060011842
resolver
ensp
ENSRNOP00065013099
resolver
enst
ENSRNOT00000060185
resolver
enst
ENSRNOT00055009283
resolver
enst
ENSRNOT00060015220
resolver
enst
ENSRNOT00065017109
resolver
genesymbol
Eipr1
resolver
genesymbol_syn
Tssc1
resolver
uniprot_entry
EIPR1_RAT
resolver
amino_acid_sequence
MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADKGVLATCYNKTSDSRVQACAAVWRMPKELESGSHESPEDPASTAQTLELLCHLDNGAQGNVACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSAALEGRGQLKFTSGRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDVSDPEEHHTEKSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHILL
uniprot
proteins
function
FUNCTION: Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network (By similarity). Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein (By similarity). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex (By similarity). Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles (PubMed:3172165). Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes (PubMed:3172165). {ECO:0000250|UniProtKB:Q53HC9, ECO:0000269|PubMed:3172165}.
uniprot
proteins
mass_dalton
43157
uniprot
proteins
protein_family
WD repeat EIPR1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27191843
uniprot
proteins
pubmed
27440922
uniprot
proteins
pubmed
3172165
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q53HC9}.
uniprot
proteins