Lancl1
entrez
114515
canonical
uniprot
Q9QX69
canonical
ensembl
ENSRNOG00000013557
resolver
ensp
ENSRNOP00000084242
resolver
enst
ENSRNOT00000108238
resolver
genesymbol
Lancl1
resolver
genesymbol_syn
Gpr69a
resolver
uniprot
Q9ER29
resolver
uniprot_entry
LANC1_RAT
resolver
uniprot_sec
Q9ER29
resolver
amino_acid_sequence
MAQRAFPNPYADYNKSLAENYFDSTGRLTPEFSHRLTNKIRELLQQMERGLKSADPQDGTGYTGWAGIAVLYLHLHNVFGDPAYLQMAHSYVKHSLNCLSRRSITFLCGDAGPLAVAAVLYHKMNSGKQAEDCITRLIHLNKIDPHVPNEMLYGRIGYIFALLFVNKNFGEEKIPQSHIQQICETILTSGEKLSRKRNFTTKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLHVSQGKLHSLVKPSVDFVCQLKFPSGNYPSCLDDTRDLLVHWCHGAPGVIYMLIQAYKVFKEEHYLCDAQQCADVIWQYGLLKKGYGLCHGAAGNAYAFLALYNLTQDAKYLYRACKFAEWCLDYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKAKFPAFEL
uniprot
proteins
ec_number
2.5.1.18
uniprot
proteins
function
FUNCTION: Functions as a glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism (By similarity). May play a role in EPS8 signaling. Binds glutathione (By similarity). {ECO:0000250|UniProtKB:O43813, ECO:0000250|UniProtKB:O89112}.
uniprot
proteins
mass_dalton
45240
uniprot
proteins
protein_family
LanC-like protein family
uniprot
proteins
pubmed
10944443
uniprot
proteins
pubmed
11376939
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
399
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O43813}. Cell membrane {ECO:0000250|UniProtKB:O43813}; Peripheral membrane protein {ECO:0000250|UniProtKB:O43813}.
uniprot
proteins