PSPN
entrez
5623
canonical
uniprot
O60542
canonical
ensembl
ENSG00000125650
resolver
ensp
ENSP00000245810
resolver
enst
ENST00000245810
resolver
genesymbol
PSPN
resolver
hgnc
HGNC:9579
resolver
uniprot_entry
PSPN_HUMAN
resolver
amino_acid_sequence
MAVGKFLLGSLLLLSLQLGQGWGPDARGVPVADGEFSSEQVAKAGGTWLGTHRPLARLRRALSGPCQLWSLTLSVAELGLGYASEEKVIFRYCAGSCPRGARTQHGLALARLQGQGRAHGGPCCRPTRYTDVAFLDDRHRWQRLPQLSAAACGCGG
uniprot
proteins
function
FUNCTION: Growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons (PubMed:11116144, PubMed:9491986). Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor (PubMed:11116144). {ECO:0000269|PubMed:11116144, ECO:0000269|PubMed:9491986}.
uniprot
proteins
mass_dalton
16600
uniprot
proteins
protein_family
GDNF subfamily
uniprot
proteins
protein_family
TGF-beta family
uniprot
proteins
pubmed
11116144
uniprot
proteins
pubmed
9491986
uniprot
proteins
sequence_length
156
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:9491986}.
uniprot
proteins