Ces1f
entrez
100125372
canonical
uniprot
Q64573
canonical
ensembl
ENSRNOG00000091108
resolver
ensp
ENSRNOP00000111327
resolver
genesymbol
Ces1f
resolver
uniprot
A2VCW1
resolver
uniprot
Q62679
resolver
uniprot_entry
EST1F_RAT
resolver
uniprot_sec
A2VCW1
resolver
uniprot_sec
Q62679
resolver
amino_acid_sequence
MCLSFLFLVSLATCVVYGNPSSPPVVDTTKGKVLGKYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYTPADFTKNSRLPVMVWIHGGGMTLGGASTYDGRVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTKDVRPAAKQIADMAGCETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQRDNKESYHFLSTVVDNVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMGFVPADVELDKKMAITLLEKFASLYGIPEDIIPVAIEKYRKGSDDSIKIRDGILAFIGDVSFSIPSVMVSRDHRDAGAPTYMYEYQYYPSFSSPQRPKHVVGDHADDLYSVFGAPILRDGASEEEIKLSKMVMKFWANFARNGNPNGRGLPHWPQYDQKEEYLQIGATTQQSQRLKAEEVAFWTQLLAKRQPQPHHNEL
uniprot
proteins
ec_number
3.1.1.1
uniprot
proteins
function
FUNCTION: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes retinyl esters (PubMed:12230550). Hydrolyzes p-nitrophenyl butyrate (PNPB), triacylglycerol and monoacylglycerol. Shows higher activity against PNPB, a short-chain fatty acid ester, than against triolein, a long-chain fatty acid ester. Shows no detectable activity against diacylglycerol, cholesterol ester or phospholipids. May play a role in adipocyte lipolysis (By similarity). {ECO:0000250|UniProtKB:Q91WU0, ECO:0000269|PubMed:12230550}.
uniprot
proteins
mass_dalton
62308
uniprot
proteins
protein_family
Type-B carboxylesterase/lipase family
uniprot
proteins
pubmed
12230550
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7961958
uniprot
proteins
pubmed
8611161
uniprot
proteins
sequence_length
561
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lipid droplet {ECO:0000250|UniProtKB:Q91WU0}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q91WU0}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q91WU0}. Microsome {ECO:0000269|PubMed:12230550}.
uniprot
proteins