Angptl8
entrez
624219
canonical
uniprot
Q8R1L8
canonical
ensembl
ENSMUSG00000047822
resolver
ensp
ENSMUSP00000058951
resolver
enst
ENSMUST00000058777
resolver
genesymbol
Angptl8
resolver
genesymbol_syn
EG624219
resolver
genesymbol_syn
Gm6484
resolver
genesymbol_syn
Rifl
resolver
genesymbol_syn
gm6484
resolver
uniprot
A0A0A0R784
resolver
uniprot
Q80WX2
resolver
uniprot_entry
A0A0A0R784_MOUSE
resolver
uniprot_entry
ANGL8_MOUSE
resolver
uniprot_entry
Q80WX2_MOUSE
resolver
amino_acid_sequence
MAVLALCLLWTLASAVRPAPVAPLGGPEPAQYEELTLLFHGALQLGQALNGVYRATEARLTEAGHSLGLYDRALEFLGTEVRQGQDATQELRTSLSEIQVEEDALHLRAEATARSLGEVARAQQALRDTVRRLQVQLRGAWLGQAHQEFETLKARADKQSHLLWALTGHVQRQQREMAEQQQWLRQIQQRLHTAALPA
uniprot
proteins
function
FUNCTION: Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787). {ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:22809513, ECO:0000269|PubMed:23150577, ECO:0000269|PubMed:24043787}.
uniprot
proteins
mass_dalton
22063
uniprot
proteins
post_translational_modification
PTM: Proteolytically cleaved at the N-terminus. {ECO:0000250|UniProtKB:Q6UXH0}.
uniprot
proteins
protein_family
ANGPTL8 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20562862
uniprot
proteins
pubmed
22569073
uniprot
proteins
pubmed
22809513
uniprot
proteins
pubmed
23150577
uniprot
proteins
pubmed
23261442
uniprot
proteins
pubmed
23623304
uniprot
proteins
pubmed
24043787
uniprot
proteins
pubmed
24353178
uniprot
proteins
pubmed
25417115
uniprot
proteins
pubmed
28038792
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22569073}.
uniprot
proteins