Med28
entrez
305391
canonical
uniprot
P68943
canonical
ensembl
ENSRNOG00000003592
resolver
ensembl
ENSRNOG00055011432
resolver
ensembl
ENSRNOG00060015564
resolver
ensembl
ENSRNOG00065005330
resolver
ensp
ENSRNOP00000004912
resolver
ensp
ENSRNOP00055015632
resolver
ensp
ENSRNOP00060021313
resolver
ensp
ENSRNOP00065005482
resolver
enst
ENSRNOT00000004912
resolver
enst
ENSRNOT00055019399
resolver
enst
ENSRNOT00060026638
resolver
enst
ENSRNOT00065007875
resolver
genesymbol
Med28
resolver
uniprot_entry
MED28_RAT
resolver
amino_acid_sequence
MAASLGGMFAGQPPGPPPPPPGLPGQASLLQAAPGAPRPSNSTLVDELESSFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDIARQTECFFLQKRLQLSVQKPDQVIKEDVSELRSELQRKDALVQKHLTKLRHWQQVLEDINVQHKKPADMPQGSLAYLEQASANIPAPLKQT
uniprot
proteins
function
FUNCTION: May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000250}.
uniprot
proteins
mass_dalton
19524
uniprot
proteins
protein_family
Mediator complex subunit 28 family
uniprot
proteins
pubmed
12149480
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
178
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=May be also cytoplasmic and membrane-associated. {ECO:0000250}.
uniprot
proteins