Mlx
entrez
21428
canonical
uniprot
O08609
canonical
ensembl
ENSMUSG00000017801
resolver
ensp
ENSMUSP00000017945
resolver
ensp
ENSMUSP00000102923
resolver
ensp
ENSMUSP00000102924
resolver
ensp
ENSMUSP00000317671
resolver
enst
ENSMUST00000017945
resolver
enst
ENSMUST00000107302
resolver
enst
ENSMUST00000107303
resolver
genesymbol
Mlx
resolver
genesymbol_syn
Tcfl4
resolver
uniprot
A2BFB0
resolver
uniprot
A2BFB1
resolver
uniprot
A2BFB2
resolver
uniprot
Q3UQB4
resolver
uniprot
Q9EQJ7
resolver
uniprot
Q9EQJ8
resolver
uniprot_entry
A2BFB0_MOUSE
resolver
uniprot_entry
A2BFB1_MOUSE
resolver
uniprot_entry
A2BFB2_MOUSE
resolver
uniprot_entry
MLX_MOUSE
resolver
uniprot_entry
Q3UQB4_MOUSE
resolver
uniprot_sec
Q9EQJ7
resolver
uniprot_sec
Q9EQJ8
resolver
amino_acid_sequence
MTEPGASPEDPWVKASFADAHAGEGRAGRARARRGSGRRGAPQLSPESPLLSGARGCREDSSHPACAKVEYAYSDNSLDPGLFVESTHKGSVVSRANSIGSTSASSVPNTDDEDSDYQQEAYKESYKDRRRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLRKDVTALKIMKVNYEQIVKAHQDNPHEGEDQVSDQVKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCEPQTLREIVIGVLHQLKNQLY
uniprot
proteins
function
FUNCTION: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. {ECO:0000269|PubMed:10593926, ECO:0000269|PubMed:11073985, ECO:0000269|PubMed:16644671}.
uniprot
proteins
mass_dalton
33339
uniprot
proteins
pubmed
10593926
uniprot
proteins
pubmed
10918583
uniprot
proteins
pubmed
11073985
uniprot
proteins
pubmed
16644671
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8973301
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform Alpha]: Cytoplasm {ECO:0000250|UniProtKB:Q9UH92}. Note=Found predominantly in the cytoplasm. {ECO:0000250|UniProtKB:Q9UH92}.; SUBCELLULAR LOCATION: [Isoform Beta]: Cytoplasm {ECO:0000250|UniProtKB:Q9UH92}. Note=Found predominantly in the cytoplasm. {ECO:0000250|UniProtKB:Q9UH92}.; SUBCELLULAR LOCATION: [Isoform Gamma]: Nucleus {ECO:0000250|UniProtKB:Q9UH92}. Note=Found predominantly in the nucleus. {ECO:0000250|UniProtKB:Q9UH92}.
uniprot
proteins