Lrrtm2
entrez
107065
canonical
uniprot
Q8BGA3
canonical
ensembl
ENSMUSG00000071862
resolver
ensp
ENSMUSP00000089225
resolver
enst
ENSMUST00000091636
resolver
genesymbol
Lrrtm2
resolver
genesymbol_syn
Kiaa0416
resolver
uniprot
Q80U08
resolver
uniprot
Q8C8L1
resolver
uniprot_entry
LRRT2_MOUSE
resolver
uniprot_entry
Q8C8L1_MOUSE
resolver
uniprot_sec
Q80U08
resolver
amino_acid_sequence
MGLHFKWPLGAPMLAAIYAMSVVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMDWTWSTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLKSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTAMATTYRDPTTEYTKISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTRLHMSNMSDQGPYNEYEPTHEGPFIIINGYGQCKCQQLPYKECEV
uniprot
proteins
function
FUNCTION: Involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity). {ECO:0000250|UniProtKB:D4A7P2}.
uniprot
proteins
mass_dalton
58816
uniprot
proteins
protein_family
LRRTM family
uniprot
proteins
pubmed
12676565
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
515
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Localized to excitatory synapses. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 422..442; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins