Mbl1
entrez
17194
canonical
uniprot
P39039
canonical
ensembl
ENSMUSG00000037780
resolver
ensp
ENSMUSP00000153147
resolver
ensp
ENSMUSP00000202733
resolver
genesymbol
Mbl1
resolver
uniprot
Q0P6H1
resolver
uniprot_entry
MBL1_MOUSE
resolver
uniprot_sec
Q0P6H1
resolver
amino_acid_sequence
MLLLPLLPVLLCVVSVSSSGSQTCEDTLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGSPGSPGPKGQKGDHGDNRAIEEKLANMEAEIRILKSKLQLTNKLHAFSMGKKSGKKLFVTNHEKMPFSKVKSLCTELQGTVAIPRNAEENKAIQEVATGIAFLGITDEATEGQFMYVTGGRLTYSNWKKDEPNNHGSGEDCVIILDNGLWNDISCQASFKAVCEFPA
uniprot
proteins
function
FUNCTION: Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway (By similarity). Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:P19999}.
uniprot
proteins
mass_dalton
25396
uniprot
proteins
post_translational_modification
PTM: Hydroxylated on lysine and proline residues within the collagen-like domain. {ECO:0000250|UniProtKB:P19999}.; PTM: O-glycosylated. O-linked glycans on hydroxylysine residues consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups. {ECO:0000250|UniProtKB:P19999}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1637828
uniprot
proteins
pubmed
1712818
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25419660
uniprot
proteins
pubmed
7766991
uniprot
proteins
sequence_length
239
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1637828, ECO:0000269|PubMed:25419660}.
uniprot
proteins