CATIP
entrez
375307
canonical
uniprot
Q7Z7H3
canonical
ensembl
ENSG00000158428
resolver
ensp
ENSP00000289388
resolver
ensp
ENSP00000520539
resolver
ensp
ENSP00000521753
resolver
ensp
ENSP00000521754
resolver
ensp
ENSP00000521755
resolver
enst
ENST00000289388
resolver
genesymbol
CATIP
resolver
genesymbol_syn
C2orf62
resolver
hgnc
HGNC:25062
resolver
uniprot_entry
CATIP_HUMAN
resolver
amino_acid_sequence
MSSKVYSTGSRAKDHQPSGPECLPLPEANAEAIDFLSSLHKEELQMLFFSETLAMVSDTGEPQGELTIEVQRGKYQEKLGMLTYCLFVHASSRGFLDKMLCGNSLLGYLSEKLELMEQHSQDFIKFLILPMERKMSLLKQDDQLAVTRSIKEGEEVKTGVTSFPWSSIKGFISEAANLVLLRVMAWRRMVPSNARFLTLDTEGKLCYLTYQNLGFQTIQVDHQQAEVFIVEQTVHAEEGIPMSCQYYLLSDGHLAKRIQVGSPGCCIITKMPILREEDEIEPRPVFEKKPLVWEEDMELYSKFLDRKEELRLGHASYLRQHPEAHALISDFLLFLLLRQPEDVVTFAAEFFGPFDPWRPSSPALGSSHRPNPFRSLEPEGDARSGAA
uniprot
proteins
disease_involvement
DISEASE: Spermatogenic failure 54 (SPGF54) [MIM:619379]: An autosomal recessive male infertility disorder characterized by oligoteratoasthenozoospermia. Semen analysis shows markedly reduced sperm counts and severely reduced or absent sperm motility. {ECO:0000269|PubMed:32503832}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Plays a role in primary ciliogenesis by modulating actin polymerization. {ECO:0000269|PubMed:24475127, ECO:0000269|PubMed:32503832}.
uniprot
proteins
mass_dalton
43900
uniprot
proteins
protein_family
CATIP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
24475127
uniprot
proteins
pubmed
32503832
uniprot
proteins
sequence_length
387
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24475127, ECO:0000269|PubMed:32503832}. Cytoplasm {ECO:0000269|PubMed:24475127, ECO:0000269|PubMed:32503832}. Cell membrane {ECO:0000269|PubMed:24475127}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24475127}. Note=Colocalized with TTC17 at F-actin rich zones and at dynamic plasma membrane protrusions.
uniprot
proteins