SLC4A9
entrez
83697
canonical
uniprot
Q96Q91
canonical
ensembl
ENSG00000113073
resolver
ensp
ENSP00000410056
resolver
ensp
ENSP00000422855
resolver
ensp
ENSP00000424424
resolver
ensp
ENSP00000427661
resolver
ensp
ENSP00000560388
resolver
ensp
ENSP00000560391
resolver
ensp
ENSP00000560398
resolver
genesymbol
SLC4A9
resolver
genesymbol_syn
AE4
resolver
genesymbol_syn
SBC5
resolver
hgnc
HGNC:11035
resolver
uniprot
B7ZL63
resolver
uniprot
D3DQD4
resolver
uniprot
D3DQD5
resolver
uniprot
D3DQD6
resolver
uniprot
E9PDK1
resolver
uniprot
Q96RM5
resolver
uniprot
Q9BXF2
resolver
uniprot
Q9BXN3
resolver
uniprot_entry
B3A4_HUMAN
resolver
uniprot_sec
B7ZL63
resolver
uniprot_sec
D3DQD4
resolver
uniprot_sec
D3DQD5
resolver
uniprot_sec
D3DQD6
resolver
uniprot_sec
E9PDK1
resolver
uniprot_sec
Q96RM5
resolver
uniprot_sec
Q9BXF2
resolver
uniprot_sec
Q9BXN3
resolver
amino_acid_sequence
MEMKLPGQEGFEASSAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPLLFIQLNELLGWPQALEWRETGSSSASLLLDMGEMPSITLSTHLHHRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVESLSPELRGQLQALLLQRPQHYNQTTGTRPCWGSTHPRKASDNEEAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGSSAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN
uniprot
proteins
function
FUNCTION: Electroneutral Cl(-)/HCO3(-) antiporter that favors chloride ion entry and efflux of hydrogencarbonate and sodium ion across the basolateral membrane and may participate in salivary secretion (PubMed:27114614). Also mediates Cl(-)/HCO3(-) exchange activity in the presence of K(+) as well as Cs(+), Li(+), and Rb(+) (By similarity). Does not contribute to Cl(-)/HCO3(-) exchanger in the apical membrane of the upper villous epithelium (By similarity). {ECO:0000250|UniProtKB:A0A494BA31, ECO:0000269|PubMed:27114614}.
uniprot
proteins
mass_dalton
108248
uniprot
proteins
protein_family
Anion exchanger (TC 2.A.31) family
uniprot
proteins
pubmed
11302728
uniprot
proteins
pubmed
11305939
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27114614
uniprot
proteins
sequence_length
983
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000250|UniProtKB:A0A494BA31}; Multi-pass membrane protein {ECO:0000255}. Note=Localized in the basolateral membrane of the cortical collecting duct (CCD)and submandibular gland (SMG) duct. {ECO:0000250|UniProtKB:A0A494BA31}.
uniprot
proteins
transmembrane_region
TRANSMEM 415..435; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 443..463; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 500..520; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 530..550; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 624..644; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 665..685; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 712..732; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 758..778; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 815..835; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 837..857; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 899..919; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins