Nr2e1
entrez
21907
canonical
uniprot
Q64104
canonical
ensembl
ENSMUSG00000019803
resolver
ensp
ENSMUSP00000019938
resolver
enst
ENSMUST00000019938
resolver
genesymbol
Nr2e1
resolver
genesymbol_syn
Tll
resolver
genesymbol_syn
Tlx
resolver
uniprot
Q78ZM1
resolver
uniprot_entry
NR2E1_MOUSE
resolver
uniprot_entry
Q78ZM1_MOUSE
resolver
amino_acid_sequence
MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEDNGAAAHFPSTALPAPAFFTAVTQLEPHGLELAAVSATPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNTDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI
uniprot
proteins
function
FUNCTION: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). Regulates cell cycle progression in neural stem cells of rhe developing brain. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells. {ECO:0000250, ECO:0000269|PubMed:10706625, ECO:0000269|PubMed:16702404, ECO:0000269|PubMed:17901127}.
uniprot
proteins
mass_dalton
42619
uniprot
proteins
protein_family
NR2 subfamily
uniprot
proteins
protein_family
Nuclear hormone receptor family
uniprot
proteins
pubmed
10706625
uniprot
proteins
pubmed
11997145
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16702404
uniprot
proteins
pubmed
17901127
uniprot
proteins
pubmed
7720587
uniprot
proteins
sequence_length
385
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407, ECO:0000269|PubMed:17901127}.
uniprot
proteins