ARHGDIG
entrez
398
canonical
uniprot
Q99819
canonical
ensembl
ENSG00000242173
resolver
ensp
ENSP00000219409
resolver
enst
ENST00000219409
resolver
genesymbol
ARHGDIG
resolver
hgnc
HGNC:680
resolver
uniprot
F1T0H7
resolver
uniprot
Q4TT69
resolver
uniprot
Q96S29
resolver
uniprot_entry
F1T0H7_HUMAN
resolver
uniprot_entry
GDIR3_HUMAN
resolver
uniprot_sec
Q4TT69
resolver
uniprot_sec
Q96S29
resolver
amino_acid_sequence
MLGLDACELGAQLLELLRLALCARVLLADKEGGPPAVDEVLDEAVPEYRAPGRKSLLEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLAVLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQEYEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD
uniprot
proteins
function
FUNCTION: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
uniprot
proteins
mass_dalton
25098
uniprot
proteins
protein_family
Rho GDI family
uniprot
proteins
pubmed
11157797
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
9113980
uniprot
proteins
pubmed
9787082
uniprot
proteins
sequence_length
225
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins