Ost4
entrez
100188932
canonical
uniprot
B0BLS0
canonical
ensembl
ENSRNOG00000074074
resolver
ensembl
ENSRNOG00055019725
resolver
ensembl
ENSRNOG00060011604
resolver
ensembl
ENSRNOG00065023708
resolver
ensp
ENSRNOP00000104721
resolver
ensp
ENSRNOP00000108552
resolver
ensp
ENSRNOP00055027311
resolver
ensp
ENSRNOP00055027312
resolver
ensp
ENSRNOP00060015477
resolver
ensp
ENSRNOP00060015483
resolver
ensp
ENSRNOP00065033102
resolver
ensp
ENSRNOP00065033128
resolver
enst
ENSRNOT00000149100
resolver
enst
ENSRNOT00000169806
resolver
enst
ENSRNOT00055033661
resolver
enst
ENSRNOT00055033662
resolver
enst
ENSRNOT00060019661
resolver
enst
ENSRNOT00060019667
resolver
enst
ENSRNOT00065040612
resolver
enst
ENSRNOT00065040637
resolver
genesymbol
Ost4
resolver
uniprot_entry
OST4_RAT
resolver
amino_acid_sequence
MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPKKQE
uniprot
proteins
function
FUNCTION: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Specifically involved in maintaining stability of STT3A-containing OST complexes. {ECO:0000250|UniProtKB:P0C6T2}.
uniprot
proteins
mass_dalton
4193
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:P0C6T2}.
uniprot
proteins
protein_family
OST4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
37
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:P0C6T2}. Endoplasmic reticulum membrane; Single-pass type III membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..25; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins