Rmi1
entrez
74386
canonical
uniprot
Q9D4G9
canonical
ensembl
ENSMUSG00000035367
resolver
ensp
ENSMUSP00000041035
resolver
ensp
ENSMUSP00000153050
resolver
ensp
ENSMUSP00000153621
resolver
ensp
ENSMUSP00000153675
resolver
ensp
ENSMUSP00000295908
resolver
ensp
ENSMUSP00000295917
resolver
enst
ENSMUST00000042450
resolver
enst
ENSMUST00000224479
resolver
enst
ENSMUST00000225815
resolver
enst
ENSMUST00000225828
resolver
genesymbol
Rmi1
resolver
uniprot
Q8C560
resolver
uniprot
Q8CI20
resolver
uniprot_entry
RMI1_MOUSE
resolver
uniprot_sec
Q8C560
resolver
uniprot_sec
Q8CI20
resolver
amino_acid_sequence
MSVASAVLRVETWLLATWHVKVPPMWLEACVNWIQEENNNATLSQAQINKQVLEQWLLTDLRDLEHPLLPDDILELPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVSAETQSTPKPWEVRPSRMLMLQLTDGVTHIQGMEYQSIPALHSGLPPGTKILVRGCILFRLGVLLLKPENVKVLGGEVDGLSEENAQEKVLARLIGELDPTVPVIPNNSIHNVPKVSGGLDAVLGPSDEELLASLDESEESAANNDVAMERSCFSTGTSSNTTPTNPSGFEPGCNISSRPKEKPPNQPTHFTDGEFDDFSLEEALLLEETVQKEQMETKASQPLTLKENTGKCMEIFSHKPSSLNHTALIHKQGNSNFDEKTSEQMIHEDKFFDCASTRNHHKRFSAHDFTNDSKISEVDDAAQQTLSSSNVHCLRNKILNRKLDLSEKSSQISKENGHPFQACSSRSFENNTYLSIGMDLHSPPFIYLSVLMARKPKEVTTVTVKAFIVTLTGNLSSSGGFWGVTAKVSDGTAYLDVDFIDEILTSMIGYSVPEMKQLRKDPLKYKTFLEGLQKCQRDLIDLCCLMTISYDPSSCKGVVLELQDVGMEHVENLKKRLNK
uniprot
proteins
function
FUNCTION: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
68465
uniprot
proteins
protein_family
RMI1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
616
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Forms foci in response to DNA damage. {ECO:0000250}.
uniprot
proteins