AKR1E2
entrez
83592
canonical
uniprot
Q96JD6
canonical
ensembl
ENSG00000165568
resolver
ensp
ENSP00000298375
resolver
ensp
ENSP00000335034
resolver
ensp
ENSP00000335603
resolver
ensp
ENSP00000623267
resolver
ensp
ENSP00000717453
resolver
genesymbol
AKR1E2
resolver
genesymbol_syn
AKR1CL2
resolver
genesymbol_syn
AKRDC1
resolver
hgnc
HGNC:23437
resolver
uniprot
Q86Z16
resolver
uniprot
Q86Z17
resolver
uniprot
Q86Z18
resolver
uniprot
Q9BU71
resolver
uniprot_entry
AKCL2_HUMAN
resolver
uniprot_sec
Q86Z16
resolver
uniprot_sec
Q86Z17
resolver
uniprot_sec
Q86Z18
resolver
uniprot_sec
Q9BU71
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by p-chloromercuribenzoic acid and alkyliodines. {ECO:0000250|UniProtKB:P82125}.
uniprot
proteins
amino_acid_sequence
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHIEY
uniprot
proteins
ec_number
1.1.1.263
uniprot
proteins
function
FUNCTION: Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro) (PubMed:12604216, PubMed:15118078). {ECO:0000250|UniProtKB:Q9DCT1, ECO:0000269|PubMed:12604216, ECO:0000269|PubMed:15118078}.
uniprot
proteins
mass_dalton
36589
uniprot
proteins
protein_family
Aldo/keto reductase family
uniprot
proteins
pubmed
12604216
uniprot
proteins
pubmed
15118078
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
320
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins