MYO19
entrez
80179
canonical
uniprot
Q96H55
canonical
ensembl
ENSG00000278259
resolver
ensembl
ENSG00000278372
resolver
ensp
ENSP00000477559
resolver
ensp
ENSP00000478437
resolver
ensp
ENSP00000479518
resolver
ensp
ENSP00000554191
resolver
ensp
ENSP00000554193
resolver
ensp
ENSP00000554195
resolver
ensp
ENSP00000599330
resolver
ensp
ENSP00000599331
resolver
ensp
ENSP00000720555
resolver
ensp
ENSP00000720556
resolver
genesymbol
MYO19
resolver
genesymbol_syn
MYOHD1
resolver
hgnc
HGNC:26234
resolver
uniprot
B4E218
resolver
uniprot
B7Z1T7
resolver
uniprot
Q59GS4
resolver
uniprot
Q9H5X2
resolver
uniprot_entry
B4E218_HUMAN
resolver
uniprot_entry
B7Z1T7_HUMAN
resolver
uniprot_entry
MYO19_HUMAN
resolver
uniprot_sec
Q59GS4
resolver
uniprot_sec
Q9H5X2
resolver
amino_acid_sequence
MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAVEGLEWSFINYQDNQPCLDLIEGSPISICSLINEECRLNRPSSAAQLQTRIETALAGSPCLGHNKLSREPSFIVVHYAGPVRYHTAGLVEKNKDPIPPELTRLLQQSQDPLLMGLFPTNPKEKTQEEPPGQSRAPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQTFLQEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAIIRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQGSIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG
uniprot
proteins
function
FUNCTION: Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane (PubMed:19932026, PubMed:23568824, PubMed:25447992). Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis (PubMed:25447992). May be involved in mitochondrial transport or positioning (PubMed:23568824). {ECO:0000250|UniProtKB:Q5SV80, ECO:0000269|PubMed:19932026, ECO:0000269|PubMed:25447992, ECO:0000305|PubMed:23568824}.
uniprot
proteins
mass_dalton
109135
uniprot
proteins
mutagenesis
MUTAGEN 135; /note="G->R: Rigor-like phenotype due to disruption of ATP-binding. Does not affect localization to mitochondrion."; /evidence="ECO:0000269|PubMed:23568824"; MUTAGEN 855; /note="R->A: Does not affect localization to mitochondrion outer membrane."; /evidence="ECO:0000269|PubMed:27126804"; MUTAGEN 882..883; /note="RK->AA: Abolishes localization to mitochondrion outer membrane."; /evidence="ECO:0000269|PubMed:27126804"; MUTAGEN 915; /note="R->A: Does not affect localization to mitochondrion outer membrane."; /evidence="ECO:0000269|PubMed:27126804"; MUTAGEN 923; /note="K->A: Does not affect localization to mitochondrion outer membrane."; /evidence="ECO:0000269|PubMed:27126804"; MUTAGEN 927..928; /note="RK->AA: Does not affect localization to mitochondrion outer membrane."; /evidence="ECO:0000269|PubMed:27126804
uniprot
proteins
protein_family
Myosin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
19932026
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23568824
uniprot
proteins
pubmed
25447992
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26659663
uniprot
proteins
pubmed
27126804
uniprot
proteins
sequence_length
970
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000269|PubMed:19932026, ECO:0000269|PubMed:23568824, ECO:0000269|PubMed:25447992, ECO:0000269|PubMed:26659663, ECO:0000269|PubMed:27126804}; Peripheral membrane protein {ECO:0000269|PubMed:27126804}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19932026}.
uniprot
proteins