Myzap
entrez
102371
canonical
uniprot
Q3UIJ9
canonical
ensembl
ENSMUSG00000041361
resolver
ensp
ENSMUSP00000091342
resolver
enst
ENSMUST00000093823
resolver
genesymbol
Myzap
resolver
genesymbol_syn
Myozap
resolver
uniprot
B2RT00
resolver
uniprot_entry
MYZAP_MOUSE
resolver
uniprot_sec
B2RT00
resolver
amino_acid_sequence
MLRSTSTVTLFSGGGAKSPGTPSRRANVCRLRLTVPPENPVPQQTEKKIERKDQPPELSNGESTKRLPQGVVYGVVRRSDPNQQKEMVVYGWSTNQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQDLSVSHAQQDYLDSHIQAQASALDSFNAMNAALASDSVGLQKTLVDVTLENSHIKDQIRHLQQTYEASMDKLREKQRQLEAAQMENQLLKMRVESSQEANAEVMREMTRKLYSQYEEKLQEAQRKHSAEKEVLLEETNSFLKAIEEANKKMEAAELSLEEKDQKIGELDRLIERMEKERHQLQLQLLEHETEMSGEMADSDKNRYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKVQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQPKTEVETREIGVGCDLLPSPTGRTREITMPSRSYTPYTRVLELSSKKTLT
uniprot
proteins
function
FUNCTION: Plays a role in cellular signaling via Rho-related GTP-binding proteins and activation of transcription factor SRF. Targets TJP1 to cell junctions (By similarity). In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity). {ECO:0000250, ECO:0000269|PubMed:20093627}.
uniprot
proteins
mass_dalton
53897
uniprot
proteins
protein_family
MYZAP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18849881
uniprot
proteins
pubmed
20093627
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20093627}. Cell membrane {ECO:0000269|PubMed:20093627}; Peripheral membrane protein {ECO:0000269|PubMed:20093627}; Cytoplasmic side {ECO:0000269|PubMed:20093627}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000269|PubMed:20093627}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:20093627}. Cell junction {ECO:0000250|UniProtKB:P0CAP1}. Note=Detected predominantly at the intercalated disk in cardiomyocytes, and at low levels on sarcomeric Z disks. Colocalizes with F-actin. Colocalizes with cortical actin.
uniprot
proteins