RIC8B
entrez
55188
canonical
uniprot
Q9NVN3
canonical
ensembl
ENSG00000111785
resolver
ensp
ENSP00000347662
resolver
ensp
ENSP00000376582
resolver
ensp
ENSP00000376583
resolver
ensp
ENSP00000647399
resolver
enst
ENST00000392837
resolver
genesymbol
RIC8B
resolver
hgnc
HGNC:25555
resolver
uniprot
A2RTZ0
resolver
uniprot
B7WPL0
resolver
uniprot
Q4G103
resolver
uniprot
Q6ZRN4
resolver
uniprot
Q86WD3
resolver
uniprot_entry
B7WPL0_HUMAN
resolver
uniprot_entry
RIC8B_HUMAN
resolver
uniprot_sec
A2RTZ0
resolver
uniprot_sec
Q4G103
resolver
uniprot_sec
Q6ZRN4
resolver
uniprot_sec
Q86WD3
resolver
amino_acid_sequence
MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPTTCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPKEELLKPMGLKPDGTITPLEEALNQYSVIEETSSDTD
uniprot
proteins
function
FUNCTION: Chaperone that specifically binds and folds nascent G(s) G-alpha proteins (GNAS and GNAL) prior to G protein heterotrimer formation, promoting their association with the plasma membrane (By similarity). Also acts as a guanine nucleotide exchange factor (GEF) for G(s) proteins by stimulating exchange of bound GDP for free GTP (By similarity). Acts as an important component for odorant signal transduction by mediating GNAL (G(olf)-alpha) folding, thereby promoting-dependent cAMP accumulation in olfactory sensory neurons (By similarity). {ECO:0000250|UniProtKB:Q80XE1}.
uniprot
proteins
mass_dalton
58825
uniprot
proteins
protein_family
Synembryn family
uniprot
proteins
pubmed
12652642
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
19690332
uniprot
proteins
sequence_length
520
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cell cortex {ECO:0000269|PubMed:12652642}. Note=Localizes to the cell cortex. {ECO:0000269|PubMed:12652642}.
uniprot
proteins