TAF5L
entrez
27097
canonical
uniprot
O75529
canonical
ensembl
ENSG00000135801
resolver
ensp
ENSP00000258281
resolver
ensp
ENSP00000355635
resolver
ensp
ENSP00000582730
resolver
genesymbol
TAF5L
resolver
genesymbol_syn
PAF65B
resolver
hgnc
HGNC:17304
resolver
uniprot
Q5TDI5
resolver
uniprot
Q5TDI6
resolver
uniprot
Q8IW31
resolver
uniprot_entry
TAF5L_HUMAN
resolver
uniprot_sec
Q5TDI5
resolver
uniprot_sec
Q5TDI6
resolver
uniprot_sec
Q8IW31
resolver
amino_acid_sequence
MKRVRTEQIQMAVSCYLKRRQYVDSDGPLKQGLRLSQTAEEMAANLTVQSESGCANIVSAAPCQAEPQQYEVQFGRLRNFLTDSDSQHSHEVMPLLYPLFVYLHLNLVQNSPKSTVESFYSRFHGMFLQNASQKDVIEQLQTTQTIQDILSNFKLRAFLDNKYVVRLQEDSYNYLIRYLQSDNNTALCKVLTLHIHLDVQPAKRTDYQLYASGSSSRSENNGLEPPDMPSPILQNEAALEVLQESIKRVKDGPPSLTTICFYAFYNTEQLLNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDILEEEDDEDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH
uniprot
proteins
function
FUNCTION: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state (By similarity). {ECO:0000250|UniProtKB:Q91WQ5, ECO:0000305|PubMed:9674419}.
uniprot
proteins
mass_dalton
66155
uniprot
proteins
protein_family
WD repeat TAF5 family
uniprot
proteins
pubmed
11124703
uniprot
proteins
pubmed
11564863
uniprot
proteins
pubmed
12601814
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
9674419
uniprot
proteins
pubmed
9674425
uniprot
proteins
sequence_length
589
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11564863, ECO:0000269|PubMed:9674425}.
uniprot
proteins