Kansl1
entrez
76719
canonical
uniprot
Q80TG1
canonical
ensembl
ENSMUSG00000018412
resolver
ensp
ENSMUSP00000018556
resolver
ensp
ENSMUSP00000102584
resolver
ensp
ENSMUSP00000102585
resolver
ensp
ENSMUSP00000102590
resolver
ensp
ENSMUSP00000307638
resolver
ensp
ENSMUSP00000307639
resolver
ensp
ENSMUSP00000307640
resolver
ensp
ENSMUSP00000307641
resolver
ensp
ENSMUSP00000307642
resolver
ensp
ENSMUSP00000307645
resolver
ensp
ENSMUSP00000307649
resolver
ensp
ENSMUSP00000307650
resolver
ensp
ENSMUSP00000307653
resolver
ensp
ENSMUSP00000307654
resolver
ensp
ENSMUSP00000307655
resolver
ensp
ENSMUSP00000307656
resolver
ensp
ENSMUSP00000307657
resolver
ensp
ENSMUSP00000307658
resolver
ensp
ENSMUSP00000307659
resolver
ensp
ENSMUSP00000327093
resolver
enst
ENSMUST00000106971
resolver
enst
ENSMUST00000106972
resolver
genesymbol
Kansl1
resolver
genesymbol_syn
1700081L11Rik
resolver
genesymbol_syn
Kiaa1267
resolver
genesymbol_syn
Nsl1
resolver
uniprot
A2A5Y4
resolver
uniprot
A2A5Y5
resolver
uniprot
Q3TT88
resolver
uniprot
Q3U5D8
resolver
uniprot
Q3V3N3
resolver
uniprot
Q7TMU3
resolver
uniprot
Q80XP7
resolver
uniprot
Q8R3L6
resolver
uniprot
Q9D9G0
resolver
uniprot_entry
A2A5Y4_MOUSE
resolver
uniprot_entry
KANL1_MOUSE
resolver
uniprot_sec
A2A5Y5
resolver
uniprot_sec
Q3TT88
resolver
uniprot_sec
Q3U5D8
resolver
uniprot_sec
Q3V3N3
resolver
uniprot_sec
Q7TMU3
resolver
uniprot_sec
Q80XP7
resolver
uniprot_sec
Q8R3L6
resolver
uniprot_sec
Q9D9G0
resolver
amino_acid_sequence
MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILISANGTKRKAIAAEDPSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPAKESLKLQGVFSKQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSSSLNGGKRSLTSSSLQGGEVGGPDSGNLKGGMTNCTLPHRSLDIQHTTLYSNNSTANKSSVNSMDQPALQGSSRLSPSTDSSSNLTNVKLEVKKSPLSSILFSALDSDTRITALLRRQADIEIRARRLQKRLQVVQAKQVERHLQHQLGGFLETTLSKLPNLESLRSRSQLMLTRKAEAALRKAASESATSEGLSNFLKSDSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQCHVPLKRRSEWRWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEAPFPDHTTDLLSLSSEVKTDHGRDKLIESVSQPSENHGILVSNITESLSTKSCGAPRPVNGVVNSLQPVLADQVPGDSSDAEEQLHKKQRLNLVSSSDGTCVAARTRPVLTCKKRRLVRPSSIVPLSKKVHRNVRSGCDVNPSCALCGSGSVNTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPTKKFSLKHRATMPCSLSDPVRKDRHKLVNSFLTTAMLKHHTDMSSPSYLTATHHPPHSPLVRQLSTSSDTSTPTSSGSQVAASTSQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDVQSLKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPASPDVSSSHSLSEFSHGQSPRSPISPELHSAPLTPVARDSLRHLASEDTRCSTPELGLDEQSVQPWERRTFPLAYSPQAECEEQLDAQDTAARCTRRTSGSKTGREAEVAPTSPPVVPLKSRHLAATVTAQRPAHR
uniprot
proteins
function
FUNCTION: Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites and promotes transcription initiation (By similarity). The NSL complex also acts as a regulator of gene expression in mitochondria (By similarity). In addition to its role in transcription, KANSL1 also plays an essential role in spindle assembly during mitosis (By similarity). Associates with microtubule ends and contributes to microtubule stability (By similarity). {ECO:0000250|UniProtKB:Q7Z3B3}.
uniprot
proteins
mass_dalton
113179
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24842875
uniprot
proteins
pubmed
24898753
uniprot
proteins
pubmed
37813994
uniprot
proteins
sequence_length
1036
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q7Z3B3}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:Q7Z3B3}. Mitochondrion {ECO:0000269|PubMed:37813994}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q7Z3B3}. Note=Concentrated in the nucleus during interphase, localizes to the spindle poles and pericentriolar region during prometaphase and metaphase, and remains associated with the spindle poles throughout anaphase. {ECO:0000250|UniProtKB:Q7Z3B3}.
uniprot
proteins