Klf11
entrez
194655
canonical
uniprot
Q8K1S5
canonical
ensembl
ENSMUSG00000020653
resolver
ensp
ENSMUSP00000020982
resolver
enst
ENSMUST00000020982
resolver
genesymbol
Klf11
resolver
genesymbol_syn
Tieg2b
resolver
genesymbol_syn
Tieg3
resolver
uniprot
Q8BHJ1
resolver
uniprot
Q8BI37
resolver
uniprot
Q8BI70
resolver
uniprot_entry
KLF11_MOUSE
resolver
uniprot_sec
Q8BHJ1
resolver
uniprot_sec
Q8BI37
resolver
uniprot_sec
Q8BI70
resolver
amino_acid_sequence
MHSPGSTGPGDGRAADIMDICESILERKRHDSERSTCSVLEQTDIEAVEALVCMSSWGQRSQMRPLTPVSDSGDVTTAVLMDTAAPDLPKDFHSFSTLCITPPQSPELTEPSTGTPVPSQVVNSKGCMVTALPPSPAGGPRTLSKREPLEPASGSSCRAVMTSVIRHTGESPAPTRFPTGPTQEQRASDSGEGQERLLDHLEALQDTRLANGLLVTNLVSCQPCLHKSGGSFPTDKGQQTGWPAAVQTCLPKNPESDLSRKITPLISVPVSSPPVLCQMIPVAGQNGLFSAFLKPPTQLPAGTIKPILPQAASMSQPVFMGPPVPQGTVMLVLPQNTFPQPAACPSSVMAIGNTKLLPLAPAPVFLASSQNCAPQVDFSRRRNYVCNFPGCRKTYFKSSHLKAHLRTHTGEKPFTCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRITLAESPGSILEPLPASG
uniprot
proteins
function
FUNCTION: Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding sites inhibiting cell growth (By similarity). Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. {ECO:0000250|UniProtKB:O14901, ECO:0000269|PubMed:14697507, ECO:0000269|PubMed:18189266}.
uniprot
proteins
mass_dalton
54054
uniprot
proteins
protein_family
Sp1 C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
14697507
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15607700
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18189266
uniprot
proteins
pubmed
20385766
uniprot
proteins
sequence_length
502
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O14901}.
uniprot
proteins