Serinc2
entrez
230779
canonical
uniprot
Q8K0E7
canonical
ensembl
ENSMUSG00000023232
resolver
ensp
ENSMUSP00000101618
resolver
ensp
ENSMUSP00000112535
resolver
ensp
ENSMUSP00000113044
resolver
enst
ENSMUST00000105996
resolver
enst
ENSMUST00000120126
resolver
enst
ENSMUST00000122374
resolver
genesymbol
Serinc2
resolver
genesymbol_syn
Tde2l
resolver
uniprot
B2KFY0
resolver
uniprot
E9Q7Q6
resolver
uniprot
Q8C6D8
resolver
uniprot_entry
B2KFY0_MOUSE
resolver
uniprot_entry
E9Q7Q6_MOUSE
resolver
uniprot_entry
Q8C6D8_MOUSE
resolver
uniprot_entry
SERC2_MOUSE
resolver
amino_acid_sequence
MGACLGACSLLSCASCLCGSAPCILCGCCPSTRNSTVSRLLFTSFLFLGVLVSIIMLSPGVESQLYKLPWVCEDRTQQPLVLQGPLDCGSLLGFRAVYRMCFATAAFFFFFMLLMICVRSSRDPRAAIQNGFWFFKFLILVGITVGAFYIPDGSFPKIWFYFGVVGSFLFILIQLILFVDFAHSWNQRWLCKAEECDSPAWYAGLFFFTFLFYLLSIAAVALMFVYYTESGACHEGKVFISLNLTFCVCVSIIAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSNVPDQKCNPHLPTKNGTGQVDLEDYSTVWWDAPSIVGLVIFILCTFFISLRSSDHRQVNSLMQTEECPAEMVQQQQVAVSDGRAYDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYSPGETRKMISTWTSVWVKICASWAGLFLYLWTLVAPLLLPNRDFS
uniprot
proteins
function
FUNCTION: Non-ATP-dependent, non-specific lipid transporter for phosphatidylserine, phosphatidylcholine, and phosphatidylethanolamine. Functions as a scramblase that flips lipids in both directions across the membrane. In contrast to SERINC3 and SERINC5, has no effect on gammaretrovirus particles infectivity. {ECO:0000250|UniProtKB:Q96SA4}.
uniprot
proteins
mass_dalton
50478
uniprot
proteins
protein_family
TDE1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
450
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q96SA4}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..27; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 40..57; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 96..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 160..182; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 203..225; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 238..257; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 264..286; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 315..337; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 380..402; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 417..439; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins