Anpep
entrez
81641
canonical
uniprot
P15684
canonical
ensembl
ENSRNOG00000014610
resolver
ensembl
ENSRNOG00055008286
resolver
ensembl
ENSRNOG00060004176
resolver
ensembl
ENSRNOG00065030192
resolver
ensp
ENSRNOP00000020002
resolver
ensp
ENSRNOP00055011228
resolver
ensp
ENSRNOP00060005262
resolver
ensp
ENSRNOP00065042891
resolver
enst
ENSRNOT00000020002
resolver
enst
ENSRNOT00055014005
resolver
enst
ENSRNOT00060006973
resolver
enst
ENSRNOT00065052113
resolver
genesymbol
Anpep
resolver
uniprot
G3V7W7
resolver
uniprot
Q9JHP4
resolver
uniprot_entry
AMPN_RAT
resolver
uniprot_entry
G3V7W7_RAT
resolver
uniprot_sec
Q9JHP4
resolver
amino_acid_sequence
MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPNIDTTELVERTEYLVVHLQGSLVKGHQYEMDSEFQGELADDLAGFYRSEYMEGGNKKVVATTQMQAADARKSFPCFDEPAMKASFNITLIHPNNLTALSNMLPKDSRTLQEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVSPNRVQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTAYPLEKSDQIALPDFNAGAMENWGLVTYRESALVFDPQSSSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEFLGADYAEPTWNLKDLIVLNDVYRVMAVDALASSHPLSSPANEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHTFQYSNTIYLDLWEHLQQAVDSQTAIKLPASVSTIMDRWILQMGFPVITVNTSTGEIYQEHFLLDPTSKPTRPSDFNYLWIVPIPYLKNGKEDHYWLETEKNQSAEFQTSSNEWLLLNINVTGYYQVNYDENNWRKIQNQLQTDLSVIPVINRAQIIHDSFNLASAGKLSITLPLSNTLFLASETEYMPWEAALSSLNYFKLMFDRSEVYGPMKRYLKKQVTPLFAYFKIKTNNWLDRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWMNNSDNNPIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRKATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRKQDATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKEDNSATGFGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS
uniprot
proteins
ec_number
3.4.11.2
uniprot
proteins
function
FUNCTION: Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (By similarity). {ECO:0000250|UniProtKB:P15144, ECO:0000250|UniProtKB:P97449}.
uniprot
proteins
mass_dalton
109449
uniprot
proteins
post_translational_modification
PTM: Sulfated. {ECO:0000250|UniProtKB:P15145}.; PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:P15144}.; PTM: May undergo proteolysis and give rise to a soluble form. {ECO:0000250|UniProtKB:P15144}.
uniprot
proteins
protein_family
Peptidase M1 family
uniprot
proteins
pubmed
11672613
uniprot
proteins
pubmed
1673322
uniprot
proteins
pubmed
2564389
uniprot
proteins
pubmed
2567164
uniprot
proteins
sequence_length
965
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:2564389}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P15144}. Note=Also found as a soluble form. {ECO:0000250|UniProtKB:P15144}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..32; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins