EXTL2
entrez
2135
canonical
uniprot
Q9UBQ6
canonical
ensembl
ENSG00000162694
resolver
ensp
ENSP00000359131
resolver
ensp
ENSP00000359132
resolver
ensp
ENSP00000444385
resolver
ensp
ENSP00000556598
resolver
ensp
ENSP00000556599
resolver
ensp
ENSP00000556600
resolver
ensp
ENSP00000556601
resolver
ensp
ENSP00000556603
resolver
ensp
ENSP00000556604
resolver
ensp
ENSP00000556605
resolver
ensp
ENSP00000610006
resolver
ensp
ENSP00000610007
resolver
ensp
ENSP00000610008
resolver
enst
ENST00000370113
resolver
enst
ENST00000370114
resolver
enst
ENST00000535414
resolver
enst
ENST00000886539
resolver
enst
ENST00000886540
resolver
enst
ENST00000886541
resolver
enst
ENST00000886546
resolver
enst
ENST00000886547
resolver
enst
ENST00000939947
resolver
enst
ENST00000939949
resolver
genesymbol
EXTL2
resolver
genesymbol_syn
EXTR2
resolver
hgnc
HGNC:3516
resolver
uniprot
B2R795
resolver
uniprot
D3DT60
resolver
uniprot
F5GZK1
resolver
uniprot
Q8N8F1
resolver
uniprot_entry
EXTL2_HUMAN
resolver
uniprot_entry
F5GZK1_HUMAN
resolver
uniprot_entry
Q8N8F1_HUMAN
resolver
uniprot_sec
B2R795
resolver
uniprot_sec
D3DT60
resolver
amino_acid_sequence
MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGKSTMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMISQFGFPYANYKRKI
uniprot
proteins
ec_number
2.4.1.223
uniprot
proteins
function
FUNCTION: Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. {ECO:0000269|PubMed:10318803}.
uniprot
proteins
mass_dalton
37466
uniprot
proteins
pathway_participation
PATHWAY: Glycan metabolism; heparan sulfate biosynthesis.
uniprot
proteins
post_translational_modification
PTM: The soluble form derives from the membrane form by proteolytic processing.
uniprot
proteins
protein_family
Glycosyltransferase 47 family
uniprot
proteins
pubmed
10318803
uniprot
proteins
pubmed
10639137
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
9450183
uniprot
proteins
pubmed
9473480
uniprot
proteins
sequence_length
330
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Processed exostosin-like 2]: Secreted. Note=A soluble form is found in the serum.
uniprot
proteins
transmembrane_region
TRANSMEM 23..43; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins