Krt2
entrez
406228
canonical
uniprot
Q6IG02
canonical
ensembl
ENSRNOG00000009563
resolver
ensp
ENSRNOP00000070051
resolver
genesymbol
Krt2
resolver
genesymbol_syn
Kb2
resolver
genesymbol_syn
Krt2a
resolver
uniprot_entry
K22E_RAT
resolver
amino_acid_sequence
MSCQISCKSRRGGGGGGGGGFRGFSSGSAVVSGGSRRSTSGFSCLSRHGGGRGGSGGGGFGSQSLVGLGGYKSISSSVAGYGGGFGGRSYGGFGGGSGFGGSGGFGGGSGFGGGRGFGGGSGFGGGSGFGGGSGFGGGSGFGGGGFGGGRFGGGPGGFGGPGGFPGGGIHEVSVNQSLLQPLDVKVDPEIQNVKSQEREQIKTLNNKFASFIDTVRFLEQQNQVLHTKWELLQQLDVGTRTTNLDPVFQAYIGILKKQVDRLTAERNSQDSELNNMQDLVEDFKKKYEDEINKRTSAENDFVTIKKDVDSCYMDKTELQAKMEMLTQEVDFLRTLYDTELSQLQQNVTDTNVILSMDNNRNLDLDSIIAEVQSQYEIIAHKSKAESEELYHSKANEELQVTAVKHGDSLKEIKMEISELNRTIQRLQGEISHVKKQCKGVQDSIADAEQRGEHAIKDARGKLTDLEEALQQGRENLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDFSDNVSVSVTSSTISSSVASKAGFGSGGQSSGGRGSYGGRGGGSTYGSGGRSSGVRGSGSGSGGGGYSSGGGSRGGSGGGGYSTGGGSRGGSSSGGGGYSSGGGSRGDSSSGGGSRGGSGGGSRGGSGGGGYSSGGGSRGGSSSGGAVSGSERGGSGSGEGCGSGVTFSFR
uniprot
proteins
function
FUNCTION: Structural component of intermediate filaments in suprabasal keratinocytes of stratified epidermis. Forms heteropolymers with type I keratins (e.g., KRT10), assembling into keratin intermediate filament networks that support mechanical integrity and resilience of the differentiating epidermis (By similarity). Contributes to terminal differentiation and cornification of keratinocytes and plays a role in establishing the epidermal barrier (By similarity). {ECO:0000250|UniProtKB:P35908, ECO:0000250|UniProtKB:Q3TTY5}.
uniprot
proteins
mass_dalton
69127
uniprot
proteins
protein_family
Intermediate filament family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15085952
uniprot
proteins
sequence_length
685
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P35908}.
uniprot
proteins