CRACD
entrez
57482
canonical
uniprot
Q6ZU35
canonical
ensembl
ENSG00000109265
resolver
ensp
ENSP00000264229
resolver
ensp
ENSP00000423366
resolver
ensp
ENSP00000444006
resolver
ensp
ENSP00000495373
resolver
ensp
ENSP00000507165
resolver
ensp
ENSP00000561296
resolver
ensp
ENSP00000561297
resolver
enst
ENST00000264229
resolver
enst
ENST00000504228
resolver
enst
ENST00000541073
resolver
enst
ENST00000646253
resolver
enst
ENST00000682029
resolver
enst
ENST00000891237
resolver
enst
ENST00000891238
resolver
genesymbol
CRACD
resolver
genesymbol_syn
CRAD
resolver
genesymbol_syn
KIAA1211
resolver
hgnc
HGNC:29219
resolver
uniprot
A0A2R8Y6P1
resolver
uniprot
F5H1N7
resolver
uniprot
Q9NTE2
resolver
uniprot
Q9NTP8
resolver
uniprot
Q9ULK9
resolver
uniprot_entry
A0A2R8Y6P1_HUMAN
resolver
uniprot_entry
CRACD_HUMAN
resolver
uniprot_entry
F5H1N7_HUMAN
resolver
uniprot_sec
Q9NTE2
resolver
uniprot_sec
Q9NTP8
resolver
uniprot_sec
Q9ULK9
resolver
amino_acid_sequence
MGTRAFSHDSIFIPDGGAESEQTVQAMSQDNILGKVKTLQQQLGKNIKFGQRSPNAIPMNKANSGEASLEEDLFLTSPMEIVTQQDIVLSDAENKSSDTPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIESVNLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKKHRRLAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGADRPGPEEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQEVDERQTMPRPYTFQVSSGGKQILFPKVNLSPVTPAKDTGLTAAPQEPKAPKASPVQHALPSSLSVPHTAILVTGAQLCGPAVNLSQIKDTACKSLLGLEEKKHAEAPAGENPPRGPGDARAGSGKAKPRQESPSSASALAEWASIRSRILKNAESDPRSSERDQLRPGDESTPRGRCDSRGNQRKTPPVNAKFSIMPAWQKFSDGGTETSKQSTEAESIRKRPMLGPSEETAPQPPPAGVRELGKGPEKSEMHREPADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPDPVMPGGEEKASPFGIKLRRTNYSLRFNCDQQAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKLTEKVETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEEKRPETAVSRLERREQLKKANTLPTSVTVEISDSAPPAPLVKEVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK
uniprot
proteins
disease_involvement
DISEASE: Note=In colorectal cancers, CRACD gene is observed to be often the target of inactivating mutations. In the absence of genetic mutations, expression levels tend to be down-regulated. {ECO:0000269|PubMed:30361697}.
uniprot
proteins
function
FUNCTION: Involved in epithelial cell integrity by acting on the maintenance of the actin cytoskeleton. Positively regulates the actin polymerization, by inhibiting the interaction of actin-capping proteins with actin. {ECO:0000269|PubMed:30361697}.
uniprot
proteins
mass_dalton
136760
uniprot
proteins
pubmed
10574462
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
27717682
uniprot
proteins
pubmed
30361697
uniprot
proteins
sequence_length
1233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000305|PubMed:30361697}.
uniprot
proteins