RNF133
entrez
168433
canonical
uniprot
Q8WVZ7
canonical
ensembl
ENSG00000188050
resolver
ensp
ENSP00000344489
resolver
enst
ENST00000340112
resolver
genesymbol
RNF133
resolver
hgnc
HGNC:21154
resolver
uniprot
A4D0W2
resolver
uniprot
Q8N7G7
resolver
uniprot_entry
RN133_HUMAN
resolver
uniprot_sec
A4D0W2
resolver
uniprot_sec
Q8N7G7
resolver
amino_acid_sequence
MHLLKVGTWRNNTASSWLMKFSVLWLVSQNCCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFEDVVVVMIGNLKGTEIFHLIKKGVLITAVVEVGRKHIIWMNHYLVSFVIVTTATLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICFERYKPNDIVRILTCKHFFHKNCIDPWILPHGTCPICKCDILKVLGIQVVVENGTEPLQVLMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: Has E3 ubiquitin-protein ligase activity (By similarity). Plays a role in male fecundity through the interaction with the E2 ubituitin-protein ligase UBE2J1 (PubMed:35831855). {ECO:0000250|UniProtKB:Q14B02, ECO:0000269|PubMed:35831855}.
uniprot
proteins
mass_dalton
42294
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000250|UniProtKB:Q14B02}.
uniprot
proteins
post_translational_modification
PTM: Auto-ubiquitinated. {ECO:0000250|UniProtKB:Q14B02}.
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
35831855
uniprot
proteins
sequence_length
376
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:35831855}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins