Fbxo25
entrez
66822
canonical
uniprot
Q9D2Y6
canonical
ensembl
ENSMUSG00000038365
resolver
ensp
ENSMUSP00000039544
resolver
ensp
ENSMUSP00000147467
resolver
ensp
ENSMUSP00000322064
resolver
ensp
ENSMUSP00000340365
resolver
enst
ENSMUST00000043520
resolver
enst
ENSMUST00000209913
resolver
genesymbol
Fbxo25
resolver
genesymbol_syn
Fbx25
resolver
uniprot
A0A1B0GRC8
resolver
uniprot
Q3UYF5
resolver
uniprot
Q9D8H3
resolver
uniprot_entry
A0A1B0GRC8_MOUSE
resolver
uniprot_entry
FBX25_MOUSE
resolver
uniprot_entry
Q3UYF5_MOUSE
resolver
uniprot_sec
Q9D8H3
resolver
amino_acid_sequence
MPFLGQDWRSPGWSWIKTEDGWKRCDPCSHELRSEDSQYTINHSIILNSGEEEIFNNECEYAAKKRKKEHFGNDTAAHSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQDIRRFTYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHQNPRLIKGLLQDLSSTLGILVRGVGKSVLVGNINIWICRLETVLSWQQQLQNLQVTKQVNTGLTLSDLPLHMLNNILYRFSDGWDIVTLGQVTPTLYMLSEDRRLWKRLCQYHFAEQQFCRHLILSEKGHIEWKLMYFTLQKYYPTKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPEHFIDLFKF
uniprot
proteins
function
FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT). {ECO:0000269|PubMed:16714087, ECO:0000269|PubMed:18287534}.
uniprot
proteins
mass_dalton
41826
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16278047
uniprot
proteins
pubmed
16714087
uniprot
proteins
pubmed
18287534
uniprot
proteins
sequence_length
357
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16714087, ECO:0000269|PubMed:18287534}. Note=In the nucleus, associates with a specific and novel subnuclear dot-like structure. Colocalized with SKP1.
uniprot
proteins