Ednrb
entrez
13618
canonical
uniprot
P48302
canonical
ensembl
ENSMUSG00000022122
resolver
ensp
ENSMUSP00000022718
resolver
ensp
ENSMUSP00000126057
resolver
ensp
ENSMUSP00000154806
resolver
ensp
ENSMUSP00000161384
resolver
enst
ENSMUST00000022718
resolver
enst
ENSMUST00000172237
resolver
enst
ENSMUST00000227824
resolver
genesymbol
Ednrb
resolver
uniprot
Q542M3
resolver
uniprot_entry
EDNRB_MOUSE
resolver
uniprot_sec
Q542M3
resolver
amino_acid_sequence
MQSPASRCGRALVALLLACGFLGVWGEKRGFPPAQATLSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRGAGVPPRSFPPPCQRNIEISKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDMITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAVFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPHRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
uniprot
proteins
function
FUNCTION: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Essential component in the normal development of two neuronal crest-derived cell lineages.
uniprot
proteins
mass_dalton
49561
uniprot
proteins
protein_family
EDNRB sub-subfamily
uniprot
proteins
protein_family
Endothelin receptor subfamily
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
8001159
uniprot
proteins
sequence_length
442
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P24530}; Multi-pass membrane protein. Note=internalized after activation by endothelins. {ECO:0000250|UniProtKB:P24530}.
uniprot
proteins
transmembrane_region
TRANSMEM 102..126; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 138..163; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 176..197; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 219..243; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 272..296; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 325..350; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 363..389; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins