NAB2
entrez
4665
canonical
uniprot
Q15742
canonical
ensembl
ENSG00000166886
resolver
ensp
ENSP00000300131
resolver
ensp
ENSP00000341491
resolver
genesymbol
NAB2
resolver
genesymbol_syn
MADER
resolver
hgnc
HGNC:7627
resolver
uniprot
B2RAK3
resolver
uniprot
O76006
resolver
uniprot
Q14797
resolver
uniprot_entry
NAB2_HUMAN
resolver
uniprot_sec
B2RAK3
resolver
uniprot_sec
O76006
resolver
uniprot_sec
Q14797
resolver
amino_acid_sequence
MHRAPSPTAEQPPGGGDSARRTLQPRLKPSARAMALPRTLGELQLYRVLQRANLLSYYETFIQQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALREWATNPGLFSQPVPAVPVSSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSPKSPLELGEKLSPLPGGPGAGDPRIWPGRSTPESDVGAGGEEEAGSPPFSPPAGGGVPEGTGAGGLAAGGTGGGPDRLEPEMVRMVVESVERIFRSFPRGDAGEVTSLLKLNKKLARSVGHIFEMDDNDSQKEEEIRKYSIIYGRFDSKRREGKQLSLHELTINEAAAQFCMRDNTLLLRRVELFSLSRQVARESTYLSSLKGSRLHPEELGGPPLKKLKQEVGEQSHPEIQQPPPGPESYVPPYRPSLEEDSASLSGESLDGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLVSHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
uniprot
proteins
function
FUNCTION: Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
56594
uniprot
proteins
post_translational_modification
PTM: Sumoylation by EGR2 represses EGR2 transcriptional activity in hindbrain. {ECO:0000269|PubMed:21836637}.
uniprot
proteins
protein_family
NAB family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
21836637
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
8649813
uniprot
proteins
pubmed
8668170
uniprot
proteins
pubmed
9126479
uniprot
proteins
sequence_length
525
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=Isoform 2 is not localized to the nucleus. {ECO:0000250}.
uniprot
proteins