Dpy19l1
entrez
315496
canonical
uniprot
D4AD75
canonical
ensembl
ENSRNOG00000026589
resolver
ensembl
ENSRNOG00055012301
resolver
ensembl
ENSRNOG00060025531
resolver
ensembl
ENSRNOG00065015158
resolver
ensp
ENSRNOP00000033222
resolver
ensp
ENSRNOP00055016902
resolver
ensp
ENSRNOP00060036699
resolver
ensp
ENSRNOP00065019660
resolver
enst
ENSRNOT00000036738
resolver
enst
ENSRNOT00055020929
resolver
enst
ENSRNOT00060044256
resolver
enst
ENSRNOT00065025119
resolver
genesymbol
Dpy19l1
resolver
uniprot_entry
D19L1_RAT
resolver
amino_acid_sequence
MVLQARSKHRDAAPRPPRPARSSPPPLNGASEVAARELGPERAPPSPGRRSTASRKGPRAETAAPAPDGLAGRLAAGLHWALGLRRGRGRTWSTLLLASFAALLHWSHITQLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLSGVWMIMNDRLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFMLNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRTTQLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFAVYVVGYIDTYKLQKIIYTHMISLVLCFVLMFGNSMLLTSYYASSLVIIWGMLAMKPQFLKMNVSELSLWVIQGCCWLFGTVTLKSLTSRIFGIADDAHIGNLLTSKFFSYKDFDTLLYTCAAEFDFMEKETPLRYTKTLLLPVVLAIVAAIGRKIINDMRGVIANQETDVRKHQVDHGELVYHALQLFAYTALGILIMRLKLFLTPHMCVMASLICSRQLFGWLFGKVHPGAVVFAVLAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIRHSTKPDAVFAGAMPTMASVKLSALRPVVNHPHYEDAGLRARTKIVYSMYSRKAPEDVKKELIKLKVNYYILEESWCIRRSKPGCSMPEIWDVEDPDNAGKTPLCNILVKDSKPHFTTVFQNSVYKVLEVIRQ
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
function
FUNCTION: C-mannosyltransferase that mediates the C-mannosylation tryptophan residues on target proteins. The reaction occurs on the luminal side of the endoplasmic reticulum and involves the transfer of a mannose unit from a dolichylphosphate mannose (Dol-P-Man) donor to an acceptor protein containing a WxxW consensus sequence. C-mannosylates the first two tryptophans in the WxxWxxWxxC sequence motif in thrombospondin (TSP) type-1 repeats of UNC5A. Regulates neurite extension during development. {ECO:0000250|UniProtKB:A6X919}.
uniprot
proteins
mass_dalton
84364
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:A6X919}.
uniprot
proteins
protein_family
Dpy-19 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
746
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A6X919}; Multi-pass membrane protein {ECO:0000250|UniProtKB:A6X919}.
uniprot
proteins
transmembrane_region
TRANSMEM 93..113; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..159; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 227..247; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 248..268; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 329..349; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 357..377; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 378..398; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 405..425; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 481..501; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 520..540; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 562..582; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins