Ndufs1
entrez
227197
canonical
uniprot
Q91VD9
canonical
ensembl
ENSMUSG00000025968
resolver
ensp
ENSMUSP00000027111
resolver
ensp
ENSMUSP00000126621
resolver
ensp
ENSMUSP00000204234
resolver
ensp
ENSMUSP00000204235
resolver
ensp
ENSMUSP00000204250
resolver
ensp
ENSMUSP00000204252
resolver
ensp
ENSMUSP00000204255
resolver
ensp
ENSMUSP00000363892
resolver
enst
ENSMUST00000027111
resolver
enst
ENSMUST00000168099
resolver
genesymbol
Ndufs1
resolver
uniprot
Q3UQ73
resolver
uniprot
Q8BM16
resolver
uniprot_entry
NDUS1_MOUSE
resolver
uniprot_sec
Q3UQ73
resolver
uniprot_sec
Q8BM16
resolver
amino_acid_sequence
MLRIPIKRALIGLSNSPKGYVRTTGTAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQNFEGNAVAAIAGGLVDAEALVALKDLLNKVDSDNLCTEEIFPTEGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGRHSFCEVLKDAKKPMVVLGSSALQRDDGAAILVAVSNMVQKIRVTTGVAAEWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKMLFLLGADGGCITRQDLPKDCFIVYQGHHGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDIEETNYFQQASELAKLVNQEVLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC
uniprot
proteins
ec_number
7.1.1.2
uniprot
proteins
function
FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:27799543, PubMed:32072193, PubMed:38575788). Essential for catalysing the entry and efficient transfer of electrons within complex I (PubMed:27799543). Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:27799543). {ECO:0000269|PubMed:27799543, ECO:0000269|PubMed:32072193, ECO:0000269|PubMed:38575788}.
uniprot
proteins
mass_dalton
79777
uniprot
proteins
post_translational_modification
PTM: Acetylation of Lys-84 is observed in liver mitochondria from fasted mice but not from fed mice.
uniprot
proteins
protein_family
Complex I 75 kDa subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
27799543
uniprot
proteins
pubmed
32072193
uniprot
proteins
pubmed
38575788
uniprot
proteins
sequence_length
727
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:38575788}; Peripheral membrane protein {ECO:0000269|PubMed:38575788}; Matrix side {ECO:0000269|PubMed:38575788}.
uniprot
proteins