Ctnnd2
entrez
18163
canonical
uniprot
O35927
canonical
ensembl
ENSMUSG00000022240
resolver
ensp
ENSMUSP00000080427
resolver
ensp
ENSMUSP00000154410
resolver
enst
ENSMUST00000081728
resolver
enst
ENSMUST00000226119
resolver
genesymbol
Ctnnd2
resolver
genesymbol_syn
Catnd2
resolver
genesymbol_syn
Nprap
resolver
uniprot
A0A2I3BR16
resolver
uniprot
B2RR80
resolver
uniprot
B7ZNF6
resolver
uniprot
E9QKH8
resolver
uniprot
Q3U8L7
resolver
uniprot_entry
A0A2I3BR16_MOUSE
resolver
uniprot_entry
B7ZNF6_MOUSE
resolver
uniprot_entry
CTND2_MOUSE
resolver
uniprot_entry
E9QKH8_MOUSE
resolver
uniprot_entry
Q3U8L7_MOUSE
resolver
uniprot_sec
B2RR80
resolver
amino_acid_sequence
MFARKQSGAAPFGAMPVPDQPPSASEKNSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETGSMSSISSAGEQFHWQTQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTSERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGDTAPSQLPARSTQARAAGQSFSQGTTGRAGHLAGSEPAPPPPPPREPFAPSLGSAFHLPDAPPAAAALYYSSSTLPAPPRGGSPLTTTQGGSPTKLQRGGSAPEGAAYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLAPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTFRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCASVDSPYSKSGPALPPEGTLARSPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGETNGKDTESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKGWAEDVAGMAYALRSLPEGAPCLPQWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNSGSKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREMISLKERKTDYESAGNNATYHGTKGEHTSRKDTMTAQNTGVSTLYRNSYGAPAEDIKQNQVSTQPVPQEPSRKDYETYQPFPNSTRNYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV
uniprot
proteins
function
FUNCTION: Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:17993462, PubMed:25807484). Involved in the regulation of canonical Wnt signaling (By similarity). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (PubMed:20623542). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. Functions as a transcriptional activator when bound to ZBTB33 (PubMed:15282317). {ECO:0000250|UniProtKB:Q9UQB3, ECO:0000269|PubMed:15282317, ECO:0000269|PubMed:17993462, ECO:0000269|PubMed:20623542, ECO:0000269|PubMed:25807484, ECO:0000269|PubMed:9971746}.
uniprot
proteins
mass_dalton
135000
uniprot
proteins
post_translational_modification
PTM: O-glycosylated. {ECO:0000269|PubMed:16452088}.; PTM: Phosphorylated by CDK5 (By similarity). Phosphorylated by GSK3B (PubMed:19706605). {ECO:0000250|UniProtKB:O35116, ECO:0000269|PubMed:19706605}.
uniprot
proteins
protein_family
Beta-catenin family
uniprot
proteins
pubmed
10626844
uniprot
proteins
pubmed
10753311
uniprot
proteins
pubmed
15282317
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
16452088
uniprot
proteins
pubmed
17993462
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
19706605
uniprot
proteins
pubmed
20623542
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
25807484
uniprot
proteins
pubmed
9342840
uniprot
proteins
pubmed
9971746
uniprot
proteins
sequence_length
1247
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15282317}. Cell junction, adherens junction {ECO:0000269|PubMed:10753311}. Cell projection, dendrite {ECO:0000250|UniProtKB:O35116}. Perikaryon {ECO:0000250|UniProtKB:O35116}.
uniprot
proteins