Atp5if1
entrez
25392
canonical
uniprot
Q03344
canonical
ensembl
ENSRNOG00000013300
resolver
ensembl
ENSRNOG00055028848
resolver
ensembl
ENSRNOG00060024975
resolver
ensembl
ENSRNOG00065028345
resolver
ensp
ENSRNOP00000018038
resolver
ensp
ENSRNOP00055041146
resolver
ensp
ENSRNOP00060035774
resolver
ensp
ENSRNOP00065040033
resolver
enst
ENSRNOT00000018038
resolver
enst
ENSRNOT00055049967
resolver
enst
ENSRNOT00060043215
resolver
enst
ENSRNOT00065048828
resolver
genesymbol
Atp5if1
resolver
genesymbol_syn
Atpi
resolver
genesymbol_syn
Atpif1
resolver
genesymbol_syn
If1
resolver
uniprot
A0JMZ8
resolver
uniprot_entry
ATIF1_RAT
resolver
uniprot_sec
A0JMZ8
resolver
amino_acid_sequence
MAGSALAVRARLGVWGMRVLQTRGFGSDSSESMDSGAGSIREAGGAFGKREKAEEDRYFREKTREQLAALKKHHEDEIDHHSKEIERLQKQIERHKKKIKYLKNSEH
uniprot
proteins
function
FUNCTION: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (By similarity). Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme (By similarity). {ECO:0000250|UniProtKB:O35143, ECO:0000250|UniProtKB:P01096}.
uniprot
proteins
mass_dalton
12248
uniprot
proteins
protein_family
ATPase inhibitor family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7612645
uniprot
proteins
pubmed
8442667
uniprot
proteins
pubmed
8448208
uniprot
proteins
sequence_length
107
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
uniprot
proteins