E2f3
entrez
13557
canonical
uniprot
O35261
canonical
ensembl
ENSMUSG00000016477
resolver
ensp
ENSMUSP00000100012
resolver
ensp
ENSMUSP00000152368
resolver
ensp
ENSMUSP00000152782
resolver
ensp
ENSMUSP00000267952
resolver
enst
ENSMUST00000102948
resolver
enst
ENSMUST00000221536
resolver
enst
ENSMUST00000222730
resolver
genesymbol
E2f3
resolver
genesymbol_syn
mKIAA0075
resolver
uniprot
A0A1Y7VML1
resolver
uniprot
A0A1Y7VND8
resolver
uniprot
Q3TMJ9
resolver
uniprot
Q3UZJ0
resolver
uniprot
Q5T0I6
resolver
uniprot
Q6PCM3
resolver
uniprot
Q6ZQJ8
resolver
uniprot_entry
A0A1Y7VML1_MOUSE
resolver
uniprot_entry
A0A1Y7VND8_MOUSE
resolver
uniprot_entry
E2F3_MOUSE
resolver
uniprot_entry
Q3TMJ9_MOUSE
resolver
uniprot_entry
Q3UZJ0_MOUSE
resolver
uniprot_entry
Q6PCM3_MOUSE
resolver
uniprot_entry
Q6ZQJ8_MOUSE
resolver
uniprot_sec
Q5T0I6
resolver
amino_acid_sequence
MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAPGTYIQILTTNPSTTSCATSLQSGALTAGPLLPSVPGTEPAASSLYTTPQGPSSRVGLLQQPPAPGRGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
uniprot
proteins
function
FUNCTION: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000269|PubMed:20176812}.
uniprot
proteins
mass_dalton
48757
uniprot
proteins
protein_family
E2F/DP family
uniprot
proteins
pubmed
15716352
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20176812
uniprot
proteins
pubmed
9149906
uniprot
proteins
pubmed
9376316
uniprot
proteins
sequence_length
457
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins