Lamp5
entrez
362220
canonical
uniprot
Q5PPI4
canonical
ensembl
ENSRNOG00000005457
resolver
ensembl
ENSRNOG00055023091
resolver
ensembl
ENSRNOG00060002414
resolver
ensembl
ENSRNOG00065028695
resolver
ensp
ENSRNOP00000007274
resolver
ensp
ENSRNOP00055032198
resolver
ensp
ENSRNOP00060002689
resolver
ensp
ENSRNOP00065040618
resolver
enst
ENSRNOT00000007274
resolver
enst
ENSRNOT00055039659
resolver
enst
ENSRNOT00060003836
resolver
enst
ENSRNOT00065049494
resolver
genesymbol
Lamp5
resolver
uniprot_entry
LAMP5_RAT
resolver
amino_acid_sequence
MDLRGRALLGGDRLRILLMFFHAMAQTVAEQEVENLSGLSTNPEKDIFVVRENGTTCLMAEFAAKFIVPYDVWASNYVDLITEQAEISLTRGAEVKGRCGHNESELQVFWVDRAYTLKMLFVKESHNTSKGLEATWKLSKVQFVYDSSEKTHFKDAVSAGKHTANSHHLSALVTPAGMSYECQAQQTISLASSDPQKTVTMILSAVHIQPFDIISDFVFSEEHKCPVDEREQLEETLPLILGLILGLVIVITLVIYHIHHKMTANQVQIPRDRSQYKHMG
uniprot
proteins
function
FUNCTION: Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. {ECO:0000250|UniProtKB:Q9D387}.
uniprot
proteins
mass_dalton
31505
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250|UniProtKB:Q9D387}.
uniprot
proteins
protein_family
LAMP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
280
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9D387}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9D387}. Cell membrane {ECO:0000250|UniProtKB:Q9D387}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9D387}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9D387}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q9D387}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9D387}. Cell projection, growth cone membrane {ECO:0000250|UniProtKB:Q9D387}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9D387}. Early endosome membrane {ECO:0000250|UniProtKB:Q9D387}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9D387}. Recycling endosome {ECO:0000250|UniProtKB:Q9D387}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q9UJQ1}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9D387}. Endosome membrane {ECO:0000250|UniProtKB:Q9UJQ1}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9D387}. Note=Recycles from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (By similarity). Colocalizes with UNC93B1 in large endosomal intracellular vesicles (By similarity). Accumulates in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) before its disappearance upon activation by CpG dinucleotides (By similarity). Associates with cortical membranes (By similarity). Localizes mostly in cytoplasmic vesicles of neuronal cell body. Localizes to synaptic vesicles in a subset of GABAergic neurons (By similarity). {ECO:0000250|UniProtKB:Q9D387, ECO:0000250|UniProtKB:Q9UJQ1}.
uniprot
proteins
transmembrane_region
TRANSMEM 236..256; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins