Prxl2b
entrez
66469
canonical
uniprot
Q9DB60
canonical
ensembl
ENSMUSG00000029059
resolver
ensp
ENSMUSP00000030935
resolver
enst
ENSMUST00000030935
resolver
genesymbol
Prxl2b
resolver
genesymbol_syn
Fam213b
resolver
uniprot_entry
PXL2B_MOUSE
resolver
amino_acid_sequence
MNVVDLGRVGACVLKHAVTGEAVELRSLWQEKACVVAGLRRFGCMVCRWIAQDLSNLRSILDQHDVRLVGVGPEALGLQEFLDGGYFSGELYLDESKQIYKELGFKRYNSLSILPAALGKPVRDVASKAKAVGIQGNLSGDLLQSGGLLVVSKGGDKVLLHFIQKSPGDYVPQENILQALGISAEVCSSKPPQCDEEVCGR
uniprot
proteins
ec_number
1.11.1.20
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha). {ECO:0000269|PubMed:18006499}.
uniprot
proteins
mass_dalton
21670
uniprot
proteins
mutagenesis
MUTAGEN 44; /note="C->S: Almost abolishes enzyme activity."; /evidence="ECO:0000269|PubMed:18006499"; MUTAGEN 47; /note="C->S: Decreased enzyme activity to retain 63% of wild type activity."; /evidence="ECO:0000269|PubMed:18006499
uniprot
proteins
protein_family
Peroxiredoxin-like PRXL2 family
uniprot
proteins
protein_family
Prostamide/prostaglandin F synthase subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18006499
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20950588
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
201
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:18006499}.
uniprot
proteins