Ctse
entrez
25424
canonical
uniprot
P16228
canonical
ensembl
ENSRNOG00000006963
resolver
ensembl
ENSRNOG00065019437
resolver
ensp
ENSRNOP00000009242
resolver
ensp
ENSRNOP00000048353
resolver
genesymbol
Ctse
resolver
uniprot
Q63701
resolver
uniprot_entry
CATE_RAT
resolver
uniprot_sec
Q63701
resolver
amino_acid_sequence
MKPLFVLLLLLLLLDLAQAQGVLHRVPLRRHQSLRKKLRAQGQLSDFWRSHNLDMIEFSESCNVDKGINEPLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYCTSPACKAHPVFHPSQSSTYMEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVEGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIPVTKQGYWQIALDGIQVGDTVMFCSEGCQAIVDTGTSLITGPPKKIKQLQEAIGATPMDGEYAVDCATLNMMPNVTFLINGVSYTLSPTAYILPDLVDGMQFCGSGFQGLDIQPPAGPLWILGDVFIRKFYSVFDRGNNQVGLAPAVP
uniprot
proteins
ec_number
3.4.23.34
uniprot
proteins
function
FUNCTION: May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
43021
uniprot
proteins
post_translational_modification
PTM: Glycosylated. The nature of the carbohydrate chain varies between cell types. In brain microglia, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In stomach and spleen, the mature enzyme contains a high mannose-type oligosaccharide. In erythrocyte membranes, the mature enzyme contains a complex-type oligosaccharide. {ECO:0000269|PubMed:2105725, ECO:0000269|PubMed:8346912, ECO:0000269|PubMed:9572291}.
uniprot
proteins
protein_family
Peptidase A1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2105725
uniprot
proteins
pubmed
7574663
uniprot
proteins
pubmed
8157122
uniprot
proteins
pubmed
8339772
uniprot
proteins
pubmed
8346912
uniprot
proteins
pubmed
8491674
uniprot
proteins
pubmed
8809073
uniprot
proteins
pubmed
9572291
uniprot
proteins
sequence_length
398
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome {ECO:0000269|PubMed:8491674, ECO:0000269|PubMed:9572291}. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
uniprot
proteins