Slc25a22
entrez
309111
canonical
uniprot
A0A0G2K5L2
canonical
ensembl
ENSRNOG00000049944
resolver
ensembl
ENSRNOG00055029518
resolver
ensembl
ENSRNOG00060033106
resolver
ensembl
ENSRNOG00065019649
resolver
ensp
ENSRNOP00000051753
resolver
genesymbol
Slc25a22
resolver
genesymbol_syn
Gc1
resolver
uniprot
D3ZRF5
resolver
uniprot
Q5FVG4
resolver
uniprot_entry
GHC1_RAT
resolver
uniprot_sec
D3ZRF5
resolver
uniprot_sec
Q5FVG4
resolver
amino_acid_sequence
MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKMLAAQAQLATQGGGQPSVEAPAAPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQEPQA
uniprot
proteins
function
FUNCTION: Mitochondrial glutamate/H(+) symporter (By similarity). Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (Probable). Plays a role in the control of glucose-stimulated insulin secretion (PubMed:19584051). {ECO:0000250|UniProtKB:Q9H936, ECO:0000269|PubMed:19584051, ECO:0000305|PubMed:19584051}.
uniprot
proteins
mass_dalton
34662
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19584051
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:19584051}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 12..32; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 62..82; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 107..127; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 189..209; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 223..243; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 292..312; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins