Mapkbp1
entrez
26390
canonical
uniprot
Q6NS57
canonical
ensembl
ENSMUSG00000033902
resolver
ensp
ENSMUSP00000068516
resolver
ensp
ENSMUSP00000155163
resolver
ensp
ENSMUSP00000213447
resolver
ensp
ENSMUSP00000213448
resolver
enst
ENSMUST00000066058
resolver
enst
ENSMUST00000229024
resolver
genesymbol
Mapkbp1
resolver
genesymbol_syn
Jnkbp1
resolver
genesymbol_syn
Kiaa0596
resolver
uniprot
A0A0A0MQA2
resolver
uniprot
A0A2R8VK23
resolver
uniprot
A2AWL8
resolver
uniprot
Q80TW5
resolver
uniprot
Q9R0L0
resolver
uniprot_entry
A0A0A0MQA2_MOUSE
resolver
uniprot_entry
A0A2R8VK23_MOUSE
resolver
uniprot_entry
MABP1_MOUSE
resolver
uniprot_sec
A2AWL8
resolver
uniprot_sec
Q80TW5
resolver
uniprot_sec
Q9R0L0
resolver
amino_acid_sequence
MMAGEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGVTVSGGRGLACDPRSGLVAYSAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAERSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGEKADSTFCITSSGLLCEFSDRRLLDKWVELRTTVAHCISVTQEYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASITEASRLFSGGVNARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEIKDSHQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSNDLIKIIYVDGNTQALLDTELPGGDKADGSLMDPRVGIRSVCISPNGQHLASGDRMGTLRIHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGEGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGIKQQGPTSPQRASGAKQHHAPVVPPSGPALSSDSDKEGEDEGTEEEELPALPILSKSTKKELASGSSPALLRSLSHWEMSRAQETMEYLDPAPVANTGPKRRGRWAQPGVELSVRSMLDLRQIETLAPSPRGPSQDSLAVSPAGPGKHGPQGPELSCVSQNERAPRLQTSQPCSCPHIIQLLSQEEGVFAQDLEPAPIEDGIVYPEPSDSPTMDTSAFQVQAPTGGSLGRMYPGSRGSEKHSPDSACSVDYSSSRLSSPEHPNEDSESTEPLSVDGISSDLEEPAEGDEDEEEEGGTGLCGLQEGGPHTPDQEQFLKQHFETLANGTAPGGPARVLERTESQSISSRFLLQVQTSPLREPSLSSSGLALTSRPDQVSQVSGEQLKGSGATPPGAPPEMEPSSGNSGPKQVAPVLLTRRHNNLDNSWASKKMAATRPLAGLQKAQSVHSLVPQDEVPSSRPLLFQEAETQGSLGSLPQAGGCSSQPHSYQNHTTSSMAKLARSISVGENPGLATEPQAPVPIRISPFNKLALPSRAHLVLDIPKPLPDRPTLTTFSPVSKGLAHNETEQSGPLVSLGKAHTTVEKHSCLGEGTTHKSRTECQAYPGPNHPCAQQLPVNNLLQGPESLQPLSPEKTRNPVESSRPGVALSQDSELALSLQQCEQLVAELQGNVRQAVELYRAVTSYKTPSAEQSHITRLLRDTFSSVRQELEVLAGAVLSSPGGSPGAVGAEQTQALLEQYSELLLRAVERRMERRL
uniprot
proteins
function
FUNCTION: Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response (By similarity). Involved in JNK signaling pathway (PubMed:10471813). {ECO:0000250|UniProtKB:O60336, ECO:0000269|PubMed:10471813}.
uniprot
proteins
mass_dalton
162892
uniprot
proteins
pubmed
10471813
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1503
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O60336}. Nucleus {ECO:0000250|UniProtKB:O60336}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:O60336}. Note=Not detected in the cilium. Localized around the poles of the mitotic spindle from prophase to anaphase in mitotic cells. {ECO:0000250|UniProtKB:O60336}.
uniprot
proteins