Crot
entrez
83842
canonical
uniprot
P11466
canonical
ensembl
ENSRNOG00000006779
resolver
ensp
ENSRNOP00000071087
resolver
ensp
ENSRNOP00000073847
resolver
enst
ENSRNOT00000090968
resolver
enst
ENSRNOT00000091799
resolver
genesymbol
Crot
resolver
genesymbol_syn
Cot
resolver
uniprot
A0A0G2JZK8
resolver
uniprot
A0A0G2K6K3
resolver
uniprot
A0ACM8Q4E5
resolver
uniprot
A6K232
resolver
uniprot
P48033
resolver
uniprot
Q6GMN6
resolver
uniprot_entry
A0A0G2JZK8_RAT
resolver
uniprot_entry
A0ACM8Q4E5_RAT
resolver
uniprot_entry
A6K232_RAT
resolver
uniprot_entry
OCTC_RAT
resolver
uniprot_sec
A0A0G2K6K3
resolver
uniprot_sec
P48033
resolver
uniprot_sec
Q6GMN6
resolver
amino_acid_sequence
MENQLAKSIEERTFQYQDSLPPLPVPSLEESLKKYLESVKPFANEDEYKKTEEIVQKFQDGVGKTLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPSPHFEHYWPAREGTQLERGSILLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVLHDGCLITPPELLRQLTYIYQKCWNEPVGPSIAALTSEERTRWAKAREYLIGLDPENLTLLEKIQSSLFVYSIEDTSPHATPENFSQVFEMLLGGDPAVRWGDKSYNLISFANGIFGCSCDHAPYDAMLMVNIAHYVDEKLLETEGRWKGSEKVRDIPLPEELAFTVDEKILNDVYQAKAQHLKAASDLQIAASTFTSFGKKLTKKEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKMLDAFAKHNKMMRDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRIQGVVVPMVHNGYGFFYHIRDDRFVVTCSSWRSCLETDAEKLVEMIFHAFHDMIHLMNTAHL
uniprot
proteins
ec_number
2.3.1.137
uniprot
proteins
function
FUNCTION: Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. {ECO:0000250|UniProtKB:Q9UKG9}.
uniprot
proteins
mass_dalton
70302
uniprot
proteins
mutagenesis
MUTAGEN 238; /note="A->D: Reduces activity by 80%. No effect on inhibition by malonyl-coenzyme A."; /evidence="ECO:0000269|PubMed:11553629"; MUTAGEN 327; /note="H->A: Loss of activity."; /evidence="ECO:0000269|PubMed:11553629"; MUTAGEN 553; /note="G->M: Lowers activity towards medium and long chain fatty acids. Increases activity towards short chain fatty acids."; /evidence="ECO:0000269|PubMed:15155769
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
uniprot
proteins
protein_family
Carnitine/choline acetyltransferase family
uniprot
proteins
pubmed
11553629
uniprot
proteins
pubmed
15155769
uniprot
proteins
pubmed
3233218
uniprot
proteins
pubmed
7495866
uniprot
proteins
sequence_length
612
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000305}.
uniprot
proteins