Galnt15
entrez
78754
canonical
uniprot
Q9D2N8
canonical
ensembl
ENSMUSG00000021903
resolver
ensp
ENSMUSP00000022460
resolver
ensp
ENSMUSP00000240184
resolver
enst
ENSMUST00000022460
resolver
genesymbol
Galnt15
resolver
genesymbol_syn
Galntl2
resolver
uniprot
A3KN88
resolver
uniprot_entry
GLT15_MOUSE
resolver
uniprot_sec
A3KN88
resolver
amino_acid_sequence
MLPRKRPRSGRSRLQFLLLFLTLGCVLMMVILLHPPPPTLHQAVTAQASKHSPDTGYRLDFGDSQEWVLEAETEGDEYSLLDGLPSFISLQEDQLLVAVASPRARRSQSQGRRQGSYQFIKHRSRRWDEEALEKDWRTEEDGEESEEVLTPLGPDSDGLNKPLSARLPLRRVLPEVRHPLCLQQHPTSGLPTASVILCFHDEAWPTLLRTVHSILDTAPRALLQEIILVDDLSQQELLKSALSEYVARLEAVKLLRSNRRLGTIGARMLGATRATGDVLVFMDAHCECHPGWLEPLLSRIADDRSRVVSPVIDVIDWKTLQYSASKLHRGTLDWKLDFRWKPLGEQEQKALPSPISPVRSPVVPREVVAVDRHYFQNTGAYDPLLSLGDSENLEMSFKAWLCGGSVEILPCSRVGHIYRSQDASSRPDPEVALKNKIIIAETWLSSFKETFYRHIPEAFTLSKVAKPDCTERLKLQRRLGCRTFHWFLANVYPELYPSDHRPRFSGKLHNTGFGLCADCQADGDILGCPMTLAPCSNNRQQQNLEHTGRKEILFGGPQRLCFDVRGGRVILQNCTEEGPAIHQQHWDFQEDGMIIHVLSGKCMEAGVQPSNKDLYLRQCDGKTSQLWRFDQIHPVDER
uniprot
proteins
ec_number
2.4.1.41
uniprot
proteins
function
FUNCTION: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
72321
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.
uniprot
proteins
protein_family
GalNAc-T subfamily
uniprot
proteins
protein_family
Glycosyltransferase 2 family
uniprot
proteins
pubmed
12651884
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
638
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 13..35; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins