SH3GL1
entrez
6455
canonical
uniprot
Q99961
canonical
ensembl
ENSG00000141985
resolver
ensp
ENSP00000269886
resolver
ensp
ENSP00000404568
resolver
ensp
ENSP00000470792
resolver
genesymbol
SH3GL1
resolver
genesymbol_syn
CNSA1
resolver
genesymbol_syn
SH3D2B
resolver
hgnc
HGNC:10830
resolver
uniprot
B4DRA1
resolver
uniprot
E7EVZ4
resolver
uniprot
M0QZV5
resolver
uniprot
Q6FGM0
resolver
uniprot
Q99668
resolver
uniprot_entry
Q6FGM0_HUMAN
resolver
uniprot_entry
SH3G1_HUMAN
resolver
uniprot_sec
B4DRA1
resolver
uniprot_sec
E7EVZ4
resolver
uniprot_sec
M0QZV5
resolver
uniprot_sec
Q99668
resolver
amino_acid_sequence
MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ
uniprot
proteins
disease_involvement
DISEASE: Note=In some cases of acute leukemia, a translocation results in the formation of a KMT2A/MLL1-EEN fusion gene. {ECO:0000269|PubMed:9122235}.
uniprot
proteins
function
FUNCTION: Implicated in endocytosis. In a first step mediates neck formation during ultrafast endocytosis and function at a second step to aid in the removal of clathrin coats from the regenerated vesicles (By similarity). May recruit other proteins to membranes with high curvature (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q62419}.
uniprot
proteins
mass_dalton
41490
uniprot
proteins
protein_family
Endophilin family
uniprot
proteins
pubmed
10542231
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17350572
uniprot
proteins
pubmed
18088087
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23285027
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
9122235
uniprot
proteins
pubmed
9169142
uniprot
proteins
sequence_length
368
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell projection, podosome {ECO:0000269|PubMed:23285027}. Note=Associated with postsynaptic endosomes in hippocampal neurons. {ECO:0000250}.
uniprot
proteins