Slc6a9
entrez
116509
canonical
uniprot
P28572
canonical
ensembl
ENSRNOG00000019484
resolver
ensp
ENSRNOP00000040252
resolver
ensp
ENSRNOP00000070161
resolver
enst
ENSRNOT00000048770
resolver
genesymbol
Slc6a9
resolver
uniprot
A0A8L2ULJ7
resolver
uniprot
A1A5N0
resolver
uniprot
Q63322
resolver
uniprot
Q63323
resolver
uniprot_entry
A0A8L2ULJ7_RAT
resolver
uniprot_entry
SC6A9_RAT
resolver
uniprot_sec
A1A5N0
resolver
uniprot_sec
Q63322
resolver
uniprot_sec
Q63323
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by sarcosine. {ECO:0000269|PubMed:1534013}.
uniprot
proteins
amino_acid_sequence
MAVAHGPVATSSPEQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLVFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPTALSGNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIGDFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPKWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPTIIFFILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTTTPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI
uniprot
proteins
function
FUNCTION: Sodium- and chloride-dependent glycine transporter (PubMed:1534013, PubMed:16181645). Essential for regulating glycine concentrations at inhibitory glycinergic synapses (By similarity). {ECO:0000250|UniProtKB:P28571, ECO:0000269|PubMed:1534013, ECO:0000269|PubMed:16181645}.
uniprot
proteins
mass_dalton
71061
uniprot
proteins
protein_family
SLC6A9 subfamily
uniprot
proteins
protein_family
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family
uniprot
proteins
pubmed
1353889
uniprot
proteins
pubmed
1534013
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16181645
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
8494645
uniprot
proteins
pubmed
9786914
uniprot
proteins
sequence_length
638
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16181645}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 41..61; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 120..140; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 218..238; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 247..267; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 292..312; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 339..359; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 382..402; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 438..458; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 462..482; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 502..522; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 542..562; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins