Phaf1
entrez
234678
canonical
uniprot
Q922R1
canonical
ensembl
ENSMUSG00000031889
resolver
ensp
ENSMUSP00000034361
resolver
enst
ENSMUST00000034361
resolver
genesymbol
Phaf1
resolver
uniprot
Q6PER2
resolver
uniprot_entry
PHAF1_MOUSE
resolver
uniprot_sec
Q6PER2
resolver
amino_acid_sequence
MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIRNVQVLYSEQSPLSHDLILNLTQDGITLLFDAFNQRLKVIEVCELTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSTEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPSGLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENAGGQTEICTTYSKWDSIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP
uniprot
proteins
function
FUNCTION: Plays a regulatory role in autophagic activity. In complex with BCAS3, associates with the autophagosome formation site during both non-selective and selective autophagy. {ECO:0000250|UniProtKB:Q9BSU1}.
uniprot
proteins
mass_dalton
47416
uniprot
proteins
protein_family
PHAF1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
422
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BSU1}. Preautophagosomal structure {ECO:0000250|UniProtKB:Q9BSU1}. Note=The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner. {ECO:0000250|UniProtKB:Q9BSU1}.
uniprot
proteins