Gnl3
entrez
290556
canonical
uniprot
Q811S9
canonical
ensembl
ENSRNOG00000028461
resolver
ensembl
ENSRNOG00055021726
resolver
ensembl
ENSRNOG00060014569
resolver
ensembl
ENSRNOG00065015428
resolver
ensp
ENSRNOP00000035860
resolver
ensp
ENSRNOP00055030300
resolver
ensp
ENSRNOP00060019848
resolver
ensp
ENSRNOP00065020131
resolver
enst
ENSRNOT00000033677
resolver
enst
ENSRNOT00055037213
resolver
enst
ENSRNOT00060024915
resolver
enst
ENSRNOT00065025623
resolver
genesymbol
Gnl3
resolver
genesymbol_syn
Ns
resolver
uniprot
Q566E0
resolver
uniprot_entry
GNL3_RAT
resolver
uniprot_sec
Q566E0
resolver
amino_acid_sequence
MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPKKDPGVPNSAPFKEALLREAELRKQQLEELKQQQKLDRQKEQERKRKLEISPDDEQSNVETQEESDEPKIKKAKSGKQNPKKLHCQELKKVIEASDIVLEVLDARDPLGCRCPQVEEAVIQSGCKKLVLVLNKSDLVPKENLENWLTYLNKELPTVVFKASTNLKNRKKTFKIKKKVVPFQSKLCCGKEALWKLLGGFQQSCGKGVQVGVVGFPNVGKSSIINSLKQERICSVGVSMGLTRSMQIVPLDKQITIIDSPCFIISPCNSPAALALRSPASIEVLRPLEAASAILSQADSQQVVLKYTVPGYKDSLDFFTKLAQRRGLHQKGGSPNVESAAKLLWSEWTGASLGYYCHPPASWNHSPHFNENITAIMKRGFNLEELEKNNAHSIQVLKGPHLTNKILFRSSGLTNGILEEKDIPEESPKQTEDQQDGDDQEHVTGEKNAEISDVTPVEETREMSPGQSTASKPSDRSFILDKMSEEDDAYDFTTDYI
uniprot
proteins
function
FUNCTION: May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). {ECO:0000250, ECO:0000269|PubMed:12464630}.
uniprot
proteins
mass_dalton
60661
uniprot
proteins
mutagenesis
MUTAGEN 256; /note="G->V: Abrogates GTP-binding and nucleolar localization."; /evidence="ECO:0000269|PubMed:15657390"; MUTAGEN 261; /note="G->V: Abrogates nucleolar localization."; /evidence="ECO:0000269|PubMed:15657390
uniprot
proteins
protein_family
TRAFAC class YlqF/YawG GTPase family
uniprot
proteins
pubmed
12464630
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15657390
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
538
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15657390}. Nucleus, nucleolus {ECO:0000269|PubMed:12464630, ECO:0000269|PubMed:15657390}. Note=Shuttles between the nucleus and nucleolus (PubMed:15657390). {ECO:0000269|PubMed:15657390}.
uniprot
proteins