TNC
entrez
3371
canonical
uniprot
P24821
canonical
ensembl
ENSG00000041982
resolver
ensp
ENSP00000265131
resolver
ensp
ENSP00000339553
resolver
ensp
ENSP00000442242
resolver
ensp
ENSP00000443478
resolver
ensp
ENSP00000516085
resolver
ensp
ENSP00000571502
resolver
ensp
ENSP00000571503
resolver
ensp
ENSP00000571504
resolver
ensp
ENSP00000571510
resolver
ensp
ENSP00000571511
resolver
ensp
ENSP00000602108
resolver
ensp
ENSP00000638492
resolver
enst
ENST00000341037
resolver
genesymbol
TNC
resolver
genesymbol_syn
HXB
resolver
hgnc
HGNC:5318
resolver
uniprot
B4E1W8
resolver
uniprot
C9IYT7
resolver
uniprot
C9J575
resolver
uniprot
C9J6D9
resolver
uniprot
C9J848
resolver
uniprot
J3QSU6
resolver
uniprot
Q14583
resolver
uniprot
Q15567
resolver
uniprot
Q5T7S3
resolver
uniprot_entry
B4E1W8_HUMAN
resolver
uniprot_entry
J3QSU6_HUMAN
resolver
uniprot_entry
TENA_HUMAN
resolver
uniprot_sec
C9IYT7
resolver
uniprot_sec
C9J575
resolver
uniprot_sec
C9J6D9
resolver
uniprot_sec
C9J848
resolver
uniprot_sec
Q14583
resolver
uniprot_sec
Q15567
resolver
uniprot_sec
Q5T7S3
resolver
amino_acid_sequence
MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA
uniprot
proteins
disease_involvement
DISEASE: Deafness, autosomal dominant, 56 (DFNA56) [MIM:615629]: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA56 is characterized by progressive hearing impairment with postlingual onset. {ECO:0000269|PubMed:23936043}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). {ECO:0000269|PubMed:19884327}.
uniprot
proteins
mass_dalton
240853
uniprot
proteins
protein_family
Tenascin family
uniprot
proteins
pubmed
1279805
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
1704365
uniprot
proteins
pubmed
1707164
uniprot
proteins
pubmed
1719530
uniprot
proteins
pubmed
18780401
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
19884327
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22654117
uniprot
proteins
pubmed
23936043
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2466295
uniprot
proteins
pubmed
26091039
uniprot
proteins
pubmed
36213313
uniprot
proteins
pubmed
7524681
uniprot
proteins
pubmed
7531707
uniprot
proteins
pubmed
8824254
uniprot
proteins
sequence_length
2201
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
uniprot
proteins