RIMS1
entrez
22999
canonical
uniprot
Q86UR5
canonical
ensembl
ENSG00000079841
resolver
ensp
ENSP00000359448
resolver
ensp
ENSP00000385649
resolver
ensp
ENSP00000389503
resolver
ensp
ENSP00000402273
resolver
ensp
ENSP00000411235
resolver
ensp
ENSP00000428328
resolver
ensp
ENSP00000428367
resolver
ensp
ENSP00000428417
resolver
ensp
ENSP00000429959
resolver
ensp
ENSP00000430359
resolver
ensp
ENSP00000430502
resolver
ensp
ENSP00000513179
resolver
genesymbol
RIMS1
resolver
genesymbol_syn
KIAA0340
resolver
genesymbol_syn
RAB3IP2
resolver
genesymbol_syn
RIM1
resolver
hgnc
HGNC:17282
resolver
uniprot
A7MBN6
resolver
uniprot
B7Z2M0
resolver
uniprot
B7Z2Q9
resolver
uniprot
B7Z3S3
resolver
uniprot
B7Z6S2
resolver
uniprot
B7Z7W2
resolver
uniprot
B7Z9Z3
resolver
uniprot
E7EX08
resolver
uniprot
E9PCB7
resolver
uniprot
E9PCZ1
resolver
uniprot
E9PF48
resolver
uniprot
E9PHF5
resolver
uniprot
E9PHR1
resolver
uniprot
O15048
resolver
uniprot
Q3ZCW0
resolver
uniprot
Q5JY21
resolver
uniprot
Q5JY25
resolver
uniprot
Q5SZK1
resolver
uniprot
Q8TDY9
resolver
uniprot
Q8TDZ5
resolver
uniprot
Q9HBA1
resolver
uniprot
Q9HBA2
resolver
uniprot
Q9HBA3
resolver
uniprot
Q9HBA4
resolver
uniprot
Q9HBA5
resolver
uniprot
Q9HBA6
resolver
uniprot_entry
B7Z7W2_HUMAN
resolver
uniprot_entry
B7Z9Z3_HUMAN
resolver
uniprot_entry
Q3ZCW0_HUMAN
resolver
uniprot_entry
RIMS1_HUMAN
resolver
uniprot_sec
A7MBN6
resolver
uniprot_sec
B7Z2M0
resolver
uniprot_sec
B7Z2Q9
resolver
uniprot_sec
B7Z3S3
resolver
uniprot_sec
B7Z6S2
resolver
uniprot_sec
E7EX08
resolver
uniprot_sec
E9PCB7
resolver
uniprot_sec
E9PCZ1
resolver
uniprot_sec
E9PF48
resolver
uniprot_sec
E9PHF5
resolver
uniprot_sec
E9PHR1
resolver
uniprot_sec
O15048
resolver
uniprot_sec
Q5JY21
resolver
uniprot_sec
Q5JY25
resolver
uniprot_sec
Q5SZK1
resolver
uniprot_sec
Q8TDY9
resolver
uniprot_sec
Q8TDZ5
resolver
uniprot_sec
Q9HBA1
resolver
uniprot_sec
Q9HBA2
resolver
uniprot_sec
Q9HBA3
resolver
uniprot_sec
Q9HBA4
resolver
uniprot_sec
Q9HBA5
resolver
uniprot_sec
Q9HBA6
resolver
amino_acid_sequence
MSSAVGPRGPRPPTVPPPMQELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMAKPAACKTPRNAENQPHQPSPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICHKTKFADGCGHLCSYCRTKFCARCGGRVSLRSNNEDKVVMWVCNLCRKQQEILTKSGAWFFGSGPQQTSQDGTLSDTATGAGSEVPREKKARLQERSRSQTPLSTAAASSQDAAPPSAPPDRSKGAEPSQQALGPEQKQASSRSRSEPPRERKKTPGLSEQNGKGALKSERKRVPKTSAQPVEGAVEERERKERRESRRLEKGRSQDYPDTPEKRDEGKAADEEKQRKEEDYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAGAALPEGKAGKRAPAAARASPPDSPRAYSAERTAETRAPGAKQLTNHSPPAPRHGPVPAEAPELKAQEPLRKQSRLDPSSAVLMRKAKREKVETMLRNDSLSSDQSESVRPSPPKPHRSKRGGKKRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKDSGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPARVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKILEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGESSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRSSARESKSTTLTVPEQQRTTHHRSRSVSPHRGNDQGKPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPVDHRTRDVDSQYLSEQDSELLMLPRAKRGRSAECLHTTRHLVRHYKTLPPKMPLLQSSSHWNIYSSILPAHTKTKSVTRQDISLHHECFNSTVLRFTDEILVSELQPFLDRARSASTNCLRPDTSLHSPERERGRWSPSLDRRRPPSPRIQIQHASPENDRHSRKSERSSIQKQTRKGTASDAERVLPTCLSRRGHAAPRATDQPVIRGKHPARSRSSEHSSIRTLCSMHHLVPGGSAPPSPLLTRMHRQRSPTQSPPADTSFSSRRGRQLPQVPVRSGSIEQASLVVEERTRQMKMKVHRFKQTTGSGSSQELDREQYSKYNIHKDQYRSCDNVSAKSSDSDVSDVSAISRTSSASRLSSTSFMSEQSERPRGRISSFTPKMQGRRMGTSGRSIMKSTSVSGEMYTLEHNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRLGADSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLTPLTRRASQSSLESSTGPPCIRS
uniprot
proteins
function
FUNCTION: Rab effector involved in exocytosis (By similarity). May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003). {ECO:0000250|UniProtKB:Q99NE5, ECO:0000269|PubMed:23999003}.
uniprot
proteins
mass_dalton
189073
uniprot
proteins
mutagenesis
MUTAGEN 796..797; /note="RR->AA: Abolishes interaction with SYT1 and CACNA1B."; /evidence="ECO:0000269|PubMed:11438518"; MUTAGEN 1591..1592; /note="KK->AA: Abolishes interaction with SYT1 and CACNA1B."; /evidence="ECO:0000269|PubMed:11438518
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by BRSK1. {ECO:0000250}.
uniprot
proteins
pubmed
11438518
uniprot
proteins
pubmed
12659814
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
23999003
uniprot
proteins
pubmed
41492970
uniprot
proteins
pubmed
9205841
uniprot
proteins
sequence_length
1692
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Synapse {ECO:0000250}. Presynaptic cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
uniprot
proteins