KRTAP22-1
entrez
337979
canonical
uniprot
Q3MIV0
canonical
ensembl
ENSG00000186924
resolver
ensp
ENSP00000333887
resolver
enst
ENST00000334680
resolver
genesymbol
KRTAP22-1
resolver
genesymbol_syn
KAP22.1
resolver
hgnc
HGNC:18947
resolver
uniprot_entry
KR221_HUMAN
resolver
amino_acid_sequence
MSFDNNYHGGQGYAKGGLGCSYGCGLSGYGYACYCPWCYERSWFSGCF
uniprot
proteins
function
FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
uniprot
proteins
mass_dalton
5275
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
48
uniprot
proteins