Tctn3
entrez
67590
canonical
uniprot
Q8R2Q6
canonical
ensembl
ENSMUSG00000025008
resolver
ensp
ENSMUSP00000025981
resolver
ensp
ENSMUSP00000121760
resolver
enst
ENSMUST00000132452
resolver
genesymbol
Tctn3
resolver
genesymbol_syn
Tect3
resolver
uniprot
A0A0R4J1W4
resolver
uniprot
Q8CDF3
resolver
uniprot
Q9CRC5
resolver
uniprot_entry
A0A0R4J1W4_MOUSE
resolver
uniprot_entry
TECT3_MOUSE
resolver
uniprot_sec
Q8CDF3
resolver
uniprot_sec
Q9CRC5
resolver
amino_acid_sequence
MCTLQLHLLLLVVLMLSETARPQPSSTARAFPTSWGLEPVTPEVPTSAPPDSSESPTPWTLSMPVNATTDPFPALPICVCDLTPGTCDLNCCCDKDCDLLHPRTVFSFCLPGSVRSSSWVCVDNSLMFRSNSPFPSRVFTDSSGTTQFCVRVNNSKANYFQKLQTVNATNFQALAAEFGGQSFPSMPPETQPPVLFYRAGDPILTYYPSWSVVSLLRQPAAVGAGGLCAESNPAGFLESKSTTCPRFFRDLASSCTSEPALDAASYYNFRVLKVPRGVTDLQNMKFQVPVTLASQASPPLLAGNTCQNIVSQVVYEIETNGTFGIQKVSVSFRQTNLTVKPGVSLQQDFIVHFRAFQQRKAAAPAAPRSGNPGYLTGKPLLVLTGDTSHSMTLLQSEGNGLCSAKRHAVQFGVNAVSGCQLRPREVNCSHLQEEVYQTLHGRPRPEHVAVFGNADPAQRGGWTRILSRDCSVSAVNCTSCCLIPVSLEIQVLWAHLGLQSNPQAHVAGARFLYQCKSVQEHQRGIEVSLTTLVNFVDITQKPEPPRDQPRIDWKLPFDFFFPFKAALSRGASVQKDSLVLILCVLLLGLLNSQTK
uniprot
proteins
function
FUNCTION: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation (By similarity). Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway. {ECO:0000250, ECO:0000269|PubMed:21725307}.
uniprot
proteins
mass_dalton
64824
uniprot
proteins
protein_family
Tectonic family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16357211
uniprot
proteins
pubmed
21565611
uniprot
proteins
pubmed
21725307
uniprot
proteins
sequence_length
595
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 576..594; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins