SRPK3
entrez
26576
canonical
uniprot
Q9UPE1
canonical
ensembl
ENSG00000184343
resolver
ensp
ENSP00000359119
resolver
ensp
ENSP00000359122
resolver
ensp
ENSP00000377376
resolver
genesymbol
SRPK3
resolver
genesymbol_syn
MSSK1
resolver
genesymbol_syn
STK23
resolver
hgnc
HGNC:11402
resolver
uniprot
Q13583
resolver
uniprot
Q4F970
resolver
uniprot
Q562F5
resolver
uniprot
Q9UM62
resolver
uniprot_entry
SRPK3_HUMAN
resolver
uniprot_sec
Q13583
resolver
uniprot_sec
Q4F970
resolver
uniprot_sec
Q562F5
resolver
uniprot_sec
Q9UM62
resolver
amino_acid_sequence
MSASTGGGGDSGGSGGSSSSSQASCGPESSGSELALATPVPQMLQGLLGSDDEEQEDPKDYCKGGYHPVKIGDVFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQAGAPPPSRSIVSTAPQEVLQTGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAATQAEDSGLRLDGGSGSTSSSGCHPGGARAGPSPASSSPAPGGGRSLSAGSQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP
uniprot
proteins
disease_involvement
DISEASE: Intellectual developmental disorder, X-linked 114 (XLID114) [MIM:301134]: A disorder characterized by mild to severe intellectual disability, developmental delay, agenesis of the corpus callosum, abnormal eye movement, and ataxia. {ECO:0000269|PubMed:39073169}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity). {ECO:0000250|UniProtKB:Q9Z0G2}.
uniprot
proteins
mass_dalton
62014
uniprot
proteins
protein_family
CMGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
11063724
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
21205200
uniprot
proteins
pubmed
39073169
uniprot
proteins
sequence_length
567
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:39073169}. Cytoplasm {ECO:0000269|PubMed:39073169}.
uniprot
proteins