Pax3
entrez
18505
canonical
uniprot
P24610
canonical
ensembl
ENSMUSG00000004872
resolver
ensp
ENSMUSP00000004994
resolver
ensp
ENSMUSP00000084320
resolver
enst
ENSMUST00000004994
resolver
enst
ENSMUST00000087086
resolver
genesymbol
Pax3
resolver
genesymbol_syn
Pax-3
resolver
uniprot
F6S8A6
resolver
uniprot
Q3TZM4
resolver
uniprot
Q3UFQ9
resolver
uniprot
Q3UGH9
resolver
uniprot
Q8BRE7
resolver
uniprot
Q8BRF1
resolver
uniprot
Q9CXI6
resolver
uniprot_entry
F6S8A6_MOUSE
resolver
uniprot_entry
PAX3_MOUSE
resolver
uniprot_entry
Q3TZM4_MOUSE
resolver
uniprot_entry
Q3UGH9_MOUSE
resolver
uniprot_entry
Q8BRF1_MOUSE
resolver
uniprot_sec
Q3UFQ9
resolver
uniprot_sec
Q8BRE7
resolver
uniprot_sec
Q9CXI6
resolver
amino_acid_sequence
MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPPTYSTAGYSMDPVTGYQYGQYGQSKPWTF
uniprot
proteins
disease_involvement
DISEASE: Note=The Splotch (Sp) mouse mutant displays defects in neural tube closure in the form of exencephaly and spina bifida. The splotch-delayed (Spd) phenotype is less severe than the other Sp alleles. {ECO:0000269|PubMed:1682057}.
uniprot
proteins
function
FUNCTION: Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 (By similarity). {ECO:0000250|UniProtKB:P23760, ECO:0000269|PubMed:1682057, ECO:0000269|PubMed:22862948}.
uniprot
proteins
mass_dalton
52949
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
1682057
uniprot
proteins
pubmed
18644785
uniprot
proteins
pubmed
2022185
uniprot
proteins
pubmed
22862948
uniprot
proteins
pubmed
8406487
uniprot
proteins
sequence_length
479
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P23760}.
uniprot
proteins