Cpz
entrez
242939
canonical
uniprot
Q8R4V4
canonical
ensembl
ENSMUSG00000036596
resolver
ensp
ENSMUSP00000039804
resolver
enst
ENSMUST00000038676
resolver
genesymbol
Cpz
resolver
uniprot
G3X945
resolver
uniprot_entry
CBPZ_MOUSE
resolver
uniprot_sec
G3X945
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by 2-mercaptomethyl-3-guanidinoethylthiopropanoic acid (MGTA) and guanidinoethylmercaptosuccinic acid (GEMSA). Inhibited by chelating agents such as EDTA and EGTA (By similarity). {ECO:0000250|UniProtKB:Q66K79}.
uniprot
proteins
amino_acid_sequence
MPTMPLLLAALAALAVLALAARPSPSCSPGPDPSGKCQRLVYTHSATCVDLHLRTCADAAYNHTSFPTPLEHRSWEAVESSPEYMLLGVIHFLLEGQCNPDLRLLGCSVLAPRCEGGHTQRPCRHVCEGLREACQPAFDAIDMAWPYFLDCAQYFAPEEEGCYDPLEELRGELDVEEALPSGLPPTFIRFAHHSYAQMVRVLKRTAARCSQVAKTYSIGRSFEGKDLVVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREVLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLASTRGVRTDHIPISQYYWWGKVAPETKAIMKWIQTIPFVLSASLHGGDLVVSYPFDFSKNPHEKKMFSPTPDEKMFKLLARAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYGLWQQNKEPLLNFLEMVHRGIKGMVTDKYGKPVKNARILVKGIRHDVTTAPDGDYWRLLPPGSHIVIAQAPGYSKVMKRVTIPLRMKKAGRVDFILHPLATGPKNFLPGPSRALPRFQDPQREPTQMDFEPPRARRQPASGSKPWWWAYFTSLSPYKPRWLLKY
uniprot
proteins
ec_number
3.4.17.-
uniprot
proteins
function
FUNCTION: Specifically cleaves substrates and peptides with C-terminal basic amino acids, especially those containing C-terminal Arg residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. {ECO:0000250|UniProtKB:Q66K79}.
uniprot
proteins
mass_dalton
73721
uniprot
proteins
protein_family
Peptidase M14 family
uniprot
proteins
pubmed
12944424
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
654
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000250|UniProtKB:Q66K79}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q66K79}. Note=Part of the secreted CPZ is bound to the extracellular matrix. {ECO:0000250|UniProtKB:Q66K79}.
uniprot
proteins