TMEM150A
entrez
129303
canonical
uniprot
Q86TG1
canonical
ensembl
ENSG00000168890
resolver
ensp
ENSP00000302715
resolver
ensp
ENSP00000334708
resolver
ensp
ENSP00000387292
resolver
ensp
ENSP00000568753
resolver
ensp
ENSP00000629639
resolver
enst
ENST00000306353
resolver
genesymbol
TMEM150A
resolver
genesymbol_syn
TMEM150
resolver
hgnc
HGNC:24677
resolver
uniprot
A8K764
resolver
uniprot
B7WPQ9
resolver
uniprot
D6W5L2
resolver
uniprot
Q8N2R6
resolver
uniprot_entry
T150A_HUMAN
resolver
uniprot_sec
A8K764
resolver
uniprot_sec
B7WPQ9
resolver
uniprot_sec
D6W5L2
resolver
uniprot_sec
Q8N2R6
resolver
amino_acid_sequence
MTAWILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSVLAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCAPESIAMI
uniprot
proteins
function
FUNCTION: Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex (PubMed:25608530). Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (PubMed:25608530). May also play a role in fasting-induced catabolism (By similarity). {ECO:0000250|UniProtKB:Q9QZE9, ECO:0000269|PubMed:25608530}.
uniprot
proteins
mass_dalton
28835
uniprot
proteins
protein_family
DRAM/TMEM150 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
25608530
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:25608530}; Multi-pass membrane protein {ECO:0000269|PubMed:25608530}. Note=Localizes mainly at the plasma membrane; only a minor fraction localizes on intracellular structures (PubMed:25608530). {ECO:0000269|PubMed:25608530}.
uniprot
proteins
transmembrane_region
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 109..129; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 212..232; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins