Pak1ip1
entrez
68083
canonical
uniprot
Q9DCE5
canonical
ensembl
ENSMUSG00000038683
resolver
ensp
ENSMUSP00000040846
resolver
enst
ENSMUST00000046951
resolver
genesymbol
Pak1ip1
resolver
uniprot
Q3UBK7
resolver
uniprot
Q80UT4
resolver
uniprot
Q8C5N6
resolver
uniprot
Q923K2
resolver
uniprot
Q9D3E9
resolver
uniprot_entry
PK1IP_MOUSE
resolver
uniprot_sec
Q3UBK7
resolver
uniprot_sec
Q80UT4
resolver
uniprot_sec
Q8C5N6
resolver
uniprot_sec
Q923K2
resolver
uniprot_sec
Q9D3E9
resolver
amino_acid_sequence
MELVAGSYEQVLFGFTVQRGPAKSGHQETWTPVADFTHHSHTASLSVLASNSRYVVSGSKDETIHIYDMKRKVEHGALVHHAGTVTCLKFHGNQHLISGAEDGHICIWDVKRWKCLKTFKAHRGHVTFLSIHPSGKLALSVGTDKTLRTWNLIEGRSAFIKNIKENAHIVEWSPSGGKYIVVVQNKVDVYRLGTASVSGTITNGKRISSVTFLSDSVLAVAGDEEVVRIFDCDSLECLCEFRAHENRVKDMVSFEVPDHHVLVTASNDGFIKMWTLPQDKKVPPSLLCEAKTGARLTCLTVWLDRAANGMASLPPAAEPCPDQPKTIEKESGDTVQEETSEPNSEKSDVSGDSKQPTKGNSPVTAKKRKMATMSEKKRKKKM
uniprot
proteins
function
FUNCTION: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly. {ECO:0000250|UniProtKB:Q9NWT1}.
uniprot
proteins
mass_dalton
42116
uniprot
proteins
pubmed
11389855
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
382
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9NWT1}.
uniprot
proteins