PHETA2
entrez
150368
canonical
uniprot
Q6ICB4
canonical
ensembl
ENSG00000177096
resolver
ensp
ENSP00000312753
resolver
ensp
ENSP00000574293
resolver
ensp
ENSP00000574294
resolver
ensp
ENSP00000593574
resolver
ensp
ENSP00000593575
resolver
ensp
ENSP00000593576
resolver
ensp
ENSP00000633641
resolver
ensp
ENSP00000633642
resolver
enst
ENST00000321753
resolver
enst
ENST00000904234
resolver
enst
ENST00000904235
resolver
enst
ENST00000923515
resolver
enst
ENST00000923516
resolver
enst
ENST00000923517
resolver
enst
ENST00000963582
resolver
enst
ENST00000963583
resolver
genesymbol
PHETA2
resolver
genesymbol_syn
FAM109B
resolver
hgnc
HGNC:27161
resolver
uniprot
Q3SXQ3
resolver
uniprot
Q8N6L9
resolver
uniprot_entry
SESQ2_HUMAN
resolver
uniprot_sec
Q3SXQ3
resolver
uniprot_sec
Q8N6L9
resolver
amino_acid_sequence
MKLNERSVAHYALSDSPADHMGFLRTWGGPGTPPTPSGTGRRCWFVLKGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAICFDAPGVRPHLLAAEGPAAQEAWVKVLSRASFGYMRLVVRELESQLQDARQSLALQRRSSWKSVASRCKPQAPNHRAAGLENGHCLSKDSSPVGLVEEAGSRSAGWGLAEWELQGPASLLLGKGQSPVSPETSCFSTLHDWYGQEIVELRQCWQKRAQGSHSKCEEQDRP
uniprot
proteins
function
FUNCTION: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. {ECO:0000269|PubMed:21233288}.
uniprot
proteins
mass_dalton
28338
uniprot
proteins
mutagenesis
MUTAGEN 224; /note="F->A: Loss of OCRL-binding."; /evidence="ECO:0000269|PubMed:21233288"; MUTAGEN 228; /note="H->A: Loss of OCRL-binding."; /evidence="ECO:0000269|PubMed:21233288"; MUTAGEN 234..235; /note="EI->AA: Loss of OCRL-binding."; /evidence="ECO:0000269|PubMed:21233288
uniprot
proteins
protein_family
Sesquipedalian family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20133602
uniprot
proteins
pubmed
21233288
uniprot
proteins
sequence_length
259
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Early endosome {ECO:0000269|PubMed:21233288}. Recycling endosome {ECO:0000269|PubMed:21233288}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:21233288}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:21233288}. Note=Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes. {ECO:0000269|PubMed:20133602, ECO:0000269|PubMed:21233288}.
uniprot
proteins