Gjb2
entrez
394266
canonical
uniprot
P21994
canonical
ensembl
ENSRNOG00000008855
resolver
ensembl
ENSRNOG00055012364
resolver
ensembl
ENSRNOG00060019553
resolver
ensembl
ENSRNOG00065029038
resolver
ensp
ENSRNOP00000011711
resolver
ensp
ENSRNOP00000082358
resolver
ensp
ENSRNOP00000102065
resolver
ensp
ENSRNOP00000104435
resolver
ensp
ENSRNOP00000110218
resolver
ensp
ENSRNOP00055017025
resolver
ensp
ENSRNOP00055017028
resolver
ensp
ENSRNOP00060027659
resolver
ensp
ENSRNOP00060027673
resolver
ensp
ENSRNOP00065041198
resolver
ensp
ENSRNOP00065041205
resolver
enst
ENSRNOT00000011711
resolver
enst
ENSRNOT00000104368
resolver
enst
ENSRNOT00000134835
resolver
enst
ENSRNOT00000146643
resolver
enst
ENSRNOT00000170567
resolver
enst
ENSRNOT00055021059
resolver
enst
ENSRNOT00055021060
resolver
enst
ENSRNOT00060033769
resolver
enst
ENSRNOT00060033784
resolver
enst
ENSRNOT00065050152
resolver
enst
ENSRNOT00065050161
resolver
genesymbol
Gjb2
resolver
genesymbol_syn
Cxn-26
resolver
uniprot_entry
CXB2_RAT
resolver
amino_acid_sequence
MDWGTLQSILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIMVSTPALLVAMHVAYRRHEKKRKFMKGEIKNEFKDIEEIKTQKVRIEGSLWWTYTTSIFFRVIFEAVFMYVFYIMYNGFFMQRLVKCNAWPCPNTVDCFISRPTEKTVFTVFMISVSGICILLNITELCYLFIRYCSGKSKRPV
uniprot
proteins
function
FUNCTION: Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. {ECO:0000250|UniProtKB:P29033}.
uniprot
proteins
mass_dalton
26451
uniprot
proteins
protein_family
Beta-type (group I) subfamily
uniprot
proteins
protein_family
Connexin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19864490
uniprot
proteins
pubmed
2557354
uniprot
proteins
pubmed
2823143
uniprot
proteins
sequence_length
226
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q00977}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P29033}. Cell junction, gap junction {ECO:0000250|UniProtKB:Q00977}. Note=Colocalizes with GJB4 at gap junction plaques in the cochlea. {ECO:0000250|UniProtKB:Q00977}.
uniprot
proteins
transmembrane_region
TRANSMEM 21..40; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033"; TRANSMEM 74..94; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033"; TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033
uniprot
proteins