Agbl3
entrez
76223
canonical
uniprot
Q8CDP0
canonical
ensembl
ENSMUSG00000038836
resolver
ensp
ENSMUSP00000110666
resolver
ensp
ENSMUSP00000110668
resolver
ensp
ENSMUSP00000110669
resolver
ensp
ENSMUSP00000116066
resolver
ensp
ENSMUSP00000118303
resolver
ensp
ENSMUSP00000297817
resolver
enst
ENSMUST00000135304
resolver
enst
ENSMUST00000148834
resolver
genesymbol
Agbl3
resolver
genesymbol_syn
Ccp3
resolver
uniprot
B2RSY8
resolver
uniprot
D6RI59
resolver
uniprot
Q09M06
resolver
uniprot
Q09M07
resolver
uniprot
Q8BSW4
resolver
uniprot
Q8R036
resolver
uniprot_entry
CBPC3_MOUSE
resolver
uniprot_entry
D6RI59_MOUSE
resolver
uniprot_sec
B2RSY8
resolver
uniprot_sec
Q09M06
resolver
uniprot_sec
Q09M07
resolver
uniprot_sec
Q8BSW4
resolver
uniprot_sec
Q8R036
resolver
amino_acid_sequence
MSEDSEEEDYSDRSISDDDDLDEDSFMKFVSDDIHPCTLLAADSIGDPFFPRTTQILLEYQLGRWVPRLRGPRDLYGVSSSGPLSPTRWPYHCEVIDEKVQHIEWTPFVPEPVYVPTGLEIEPVYPNSKEDTVVYLAEDDHLCKAYKEPCFVYSRVGGNRTSLKQPVDNCDNTLVFEARFESGNLQKVVKVADHEYELTVRPDLFTNKHTQWYYFQVTNTQAEIVYRFTIVNFTKPASLYNRGMKPLFYSEKEAKTHNIGWQRIGDQIKYYKNNLGQDGRHFFSLTWTFQFPHSQDTCYFAHCYPYTYSNLQEYLSGINSDPVRSKFCKIRVLCHTLARNMVYVLTITTPLKTSDSKRKAVILTARVHPGETNSSWIMKGFLDYILGDSSDARLLRDTFIFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLLKESFPSVWYTRNMINRLMEKREVILYCDLHGHSRKQNIFMYGCDGSSRSKTKGLYLQQRIFPLMLSKNCPNIFSFSACKFNVQKSKEGTGRVVMWKMGIRNSFTLEATFCGSTLGNKRGTHFGTKDLESMGYHFCDSLLDYCDPDRSKYYQCLKELEEMEKHLSSERVSDNTDTSLVEISLDVESSSRGSDSSESNDTQTYLLKVTSQARNKKKYLKTKRERNAILANCQNNMQEVYGKEHLLQRHDESNSDGNDPRIDAPDVYVAHCFRRPLPNQGVVKIPGQRFYPGKTWSSSQRMIKSLNKDHRTCILETCKNPIQEVQSRGINIHESCFKMAKCPMNKRPSHWIEKTRIPTESHHQLKSKAKRCSSFQSKRTGTNWTDDEKRIYRDKRIAQTQEILKYLLPIVESSQNRKSTQMNNLINPIANLQQHQLIPTACINRRRYSIPWTPTRNLPFKAQRNLMTDTSEWLQSVPLGSFESLLPLCNLQKKTKHFELWGKKAKDVQLATSQWEAVPLSSNMDASIIRGNSVLQPKEFTMRSSKQRIPYLTKTSKKPSESDGLLTFQLKIHRNS
uniprot
proteins
ec_number
3.4.17.-
uniprot
proteins
function
FUNCTION: Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins (PubMed:25103237). Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein (PubMed:25103237). Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate (PubMed:25103237). Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK (PubMed:25103237). May catalyze the hydrolysis of aspartate from the carboxy-terminus of target proteins (PubMed:25103237). Does not show detyrosinase or deglycylase activities from the carboxy-terminus of target proteins (PubMed:25103237). {ECO:0000269|PubMed:25103237}.
uniprot
proteins
mass_dalton
116378
uniprot
proteins
mutagenesis
MUTAGEN 540; /note="E->A: Abolishes deglutamylase activity."; /evidence="ECO:0000269|PubMed:25103237
uniprot
proteins
protein_family
Peptidase M14 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17244818
uniprot
proteins
pubmed
25103237
uniprot
proteins
sequence_length
1006
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:17244818}.
uniprot
proteins