Kcna7
entrez
16495
canonical
uniprot
Q17ST2
canonical
ensembl
ENSMUSG00000038201
resolver
ensp
ENSMUSP00000103403
resolver
genesymbol
Kcna7
resolver
genesymbol_syn
Kcnc7
resolver
uniprot
O70259
resolver
uniprot_entry
KCNA7_MOUSE
resolver
uniprot_sec
O70259
resolver
amino_acid_sequence
MLFLPADTGHPTGVAAASGPHVRSPVARAVRAMEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPVRRSRFYDGARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVSFYGLGAAALARLREDEGCAVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDDPGLAPVAAATGPFLARLNGSSPMPGAPPRQPFNDPFFVVETLCICWFSFELLVRLVACPSKAVFFKNVMNLIDFVAILPYFVALGTELARQRGVGQPAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDTHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMYSHVDTQPCGTLEGKANGGLVDSEVPELLPPLWPPAGKHMVTEV
uniprot
proteins
function
FUNCTION: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channels formed by isoform 1 inactivate faster than channels formed by isoform 2. {ECO:0000269|PubMed:11896454, ECO:0000269|PubMed:16801386, ECO:0000269|PubMed:9488722}.
uniprot
proteins
mass_dalton
53948
uniprot
proteins
protein_family
A (Shaker) (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv1.7/KCNA7 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
11896454
uniprot
proteins
pubmed
16801386
uniprot
proteins
pubmed
9488722
uniprot
proteins
sequence_length
489
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:11896454, ECO:0000269|PubMed:16801386, ECO:0000269|PubMed:9488722}; Multi-pass membrane protein {ECO:0000269|PubMed:11896454, ECO:0000269|PubMed:16801386, ECO:0000269|PubMed:9488722}.
uniprot
proteins
transmembrane_region
TRANSMEM 176..196; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 242..262; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 274..294; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 309..328; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 345..365; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 406..426; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins