Kcng1
entrez
296395
canonical
uniprot
D4AD53
canonical
ensembl
ENSRNOG00000054314
resolver
ensembl
ENSRNOG00055004916
resolver
ensembl
ENSRNOG00060001121
resolver
ensembl
ENSRNOG00065013187
resolver
ensp
ENSRNOP00000069311
resolver
ensp
ENSRNOP00055005891
resolver
ensp
ENSRNOP00060000785
resolver
ensp
ENSRNOP00065016771
resolver
enst
ENSRNOT00000081648
resolver
enst
ENSRNOT00055007833
resolver
enst
ENSRNOT00060001555
resolver
enst
ENSRNOT00065021630
resolver
genesymbol
Kcng1
resolver
uniprot_entry
KCNG1_RAT
resolver
amino_acid_sequence
MTLLPGDNSDYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLGPQDDLHQSISLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREDEEEALDSEDQESEGPSTSEGRLSRCMRRLRDMVEKPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN
uniprot
proteins
function
FUNCTION: Regulatory alpha-subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1 or KCNB2, can modulate their expression and their gating kinetics by acting on deactivation upon repolarization and inactivation during maintained depolarization (PubMed:8980147, PubMed:9305895, PubMed:9696692). Potassium channel subunit that does not form functional channels by itself (PubMed:8980147, PubMed:9305895). {ECO:0000269|PubMed:8980147, ECO:0000269|PubMed:9305895, ECO:0000269|PubMed:9696692}.
uniprot
proteins
mass_dalton
58027
uniprot
proteins
protein_family
G (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv6.1/KCNG1 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
8980147
uniprot
proteins
pubmed
9305895
uniprot
proteins
pubmed
9696692
uniprot
proteins
sequence_length
514
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q14721}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 225..246; /note="Helical; Name=Segment S1"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 268..289; /note="Helical; Name=Segment S2"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 301..321; /note="Helical; Name=Segment S3"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 339..359; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 375..396; /note="Helical; Name=Segment S5"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 439..467; /note="Helical; Name=Segment S6"; /evidence="ECO:0000250|UniProtKB:P63142
uniprot
proteins