Slc49a4
entrez
303902
canonical
uniprot
Q66H95
canonical
ensembl
ENSRNOG00000002240
resolver
ensembl
ENSRNOG00055017450
resolver
ensembl
ENSRNOG00060017297
resolver
ensembl
ENSRNOG00065018920
resolver
ensp
ENSRNOP00000003048
resolver
ensp
ENSRNOP00055023721
resolver
ensp
ENSRNOP00060023748
resolver
ensp
ENSRNOP00065025338
resolver
enst
ENSRNOT00000003048
resolver
enst
ENSRNOT00055029531
resolver
enst
ENSRNOT00060029530
resolver
enst
ENSRNOT00065031777
resolver
genesymbol
Slc49a4
resolver
genesymbol_syn
Dirc2
resolver
uniprot_entry
DIRC2_RAT
resolver
amino_acid_sequence
MGSGWSSEEEERQPLLGPGLGPAPGATRRGREAAAVLPAAGPSPGRVYGRRWLVLLLFSLLAFAQGLVWNTWGPIQNSARQAYSFTGWDIALLVLWGPIGFLPCFAFMWLLDKRGLRITVLLTSFLMVLGTGLRCIPVSDLTLKKRLIHGGQILNGLAGPTVMNAAPFLSTTWFSADERATATAIASMLSYLGGACAFLVGPLVVPAPNGTAPLLTAESSRDHIKDRIETVLYAEFGVVCLIFSATLAYFPPRPPLPPSVAAASQRLSYRRSFCRLLSNLRFLMIALAYAIPLGVFAGWSGVLDLILTPVHVSQVDAGWIGFWSIVGGCVVGIAMARFADFIRGMLKLILLLLFSGATLSSTWFTLTCLNSVTHLPLTTVTLYASCILLGVFLNSSVPIFFELFVETVYPVPEGITCGVVTFLSNMFMGVLLFFVTFYHTELSWFNWCLPGSCLLSLLLILCFRESYDRLYLDVVVSV
uniprot
proteins
function
FUNCTION: Mediates H(+)-dependent pyridoxine transport. {ECO:0000250|UniProtKB:Q96SL1}.
uniprot
proteins
mass_dalton
52030
uniprot
proteins
post_translational_modification
PTM: Cleaved in lysosomes by cathepsin L between Leu-214 and Ala-261, generating a N-glycosylated N-terminal and a non-glycosylated C-terminal fragment. {ECO:0000250|UniProtKB:Q96SL1}.
uniprot
proteins
protein_family
Major facilitator superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
478
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q96SL1}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 52..72; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 90..110; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 118..138; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 153..173; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 185..205; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 282..302; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 315..335; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 348..368; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 385..405; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 415..435; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 443..463; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins