Tdo2
entrez
64206
canonical
uniprot
P21643
canonical
ensembl
ENSRNOG00000011612
resolver
ensembl
ENSRNOG00055001502
resolver
ensembl
ENSRNOG00060007169
resolver
ensembl
ENSRNOG00065030816
resolver
ensp
ENSRNOP00000015732
resolver
ensp
ENSRNOP00055001832
resolver
ensp
ENSRNOP00060008885
resolver
ensp
ENSRNOP00065043622
resolver
enst
ENSRNOT00000015732
resolver
enst
ENSRNOT00055002423
resolver
enst
ENSRNOT00060011803
resolver
enst
ENSRNOT00065053109
resolver
genesymbol
Tdo2
resolver
genesymbol_syn
Tdo
resolver
uniprot
Q5EBC2
resolver
uniprot
Q6LBW3
resolver
uniprot_entry
T23O_RAT
resolver
uniprot_sec
Q5EBC2
resolver
uniprot_sec
Q6LBW3
resolver
amino_acid_sequence
MSGCPFSGNSVGYTLKNLSMEDNEEDGAQTGVNRASKGGLIYGDYLQLEKILNAQELQSEIKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVMTRMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHYRDNFEGDYNELLLKSEQEQTLLQLVEAWLERTPGLEPHGFNFWGKFEKNILKGLEEEFLKIQAKKDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGSKAGTGGSSGYYYLRSTVSDRYKVFVDLFNLSSYLVPRHWIPKMNPIIHKFLYTAEYSDSSYFSSDESD
uniprot
proteins
ec_number
1.13.11.11
uniprot
proteins
function
FUNCTION: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. {ECO:0000255|HAMAP-Rule:MF_03020}.
uniprot
proteins
mass_dalton
47857
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2. {ECO:0000255|HAMAP-Rule:MF_03020}.
uniprot
proteins
protein_family
3-dioxygenase family
uniprot
proteins
protein_family
Tryptophan 2
uniprot
proteins
pubmed
1511007
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2372286
uniprot
proteins
pubmed
3582368
uniprot
proteins
pubmed
6327261
uniprot
proteins
sequence_length
406
uniprot
proteins