Chsy1
entrez
269941
canonical
uniprot
Q6ZQ11
canonical
ensembl
ENSMUSG00000032640
resolver
ensp
ENSMUSP00000047487
resolver
enst
ENSMUST00000036372
resolver
genesymbol
Chsy1
resolver
genesymbol_syn
Kiaa0990
resolver
uniprot_entry
CHSS1_MOUSE
resolver
amino_acid_sequence
MAARGRRAWLSMLLGLVLGFVLASRLVLPRASELKRVGPRRRPSPEGCRPGQEASQPGGARGDARGAQLWPQGSAAEGVPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVEFFSSEGSDTSIPIPVVPLRGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLESFLRSLNSSEPLFLGQTGLGTTEEMGKLALEPGENFCMGGPGVILSREVLRRMAPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCVWSYEMQQLFYENYEQNKKGYIRDLHSSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTIQLHREIVLMSKYSSTEIQKEDLQLGIPPSFMRFQARQREEILEWEFLTGKYLYSATDGQPPRRGMDSAQREALDDIVMQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKGKKMTVPVRRHAYLQQTFSKMQFVEHEELDAQELADRINQDSGSLSFLSNSLKKLVAFQLPGSKTEHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNLNVKLVILLFNSDSNPDKAKQVELMRDYRVKYPKADMQVLPVSGGFSRALALEVGSSQFNNESLLFFCDVDLVFTAEFLQRCRANTVLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHIHHPVVCDPNLDPKQYKMCLGSKASTFGSTQQLAEMWLEKNDPSYSKGGSHGSARTA
uniprot
proteins
ec_number
2.4.1.175
uniprot
proteins
ec_number
2.4.1.226
uniprot
proteins
function
FUNCTION: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. {ECO:0000250|UniProtKB:Q86X52}.
uniprot
proteins
mass_dalton
91383
uniprot
proteins
protein_family
Chondroitin N-acetylgalactosaminyltransferase family
uniprot
proteins
pubmed
14621295
uniprot
proteins
sequence_length
800
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:Q86X52}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q86X52}. Secreted {ECO:0000250|UniProtKB:Q86X52}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins