PTH2
entrez
113091
canonical
uniprot
Q96A98
canonical
ensembl
ENSG00000142538
resolver
ensp
ENSP00000270631
resolver
ensp
ENSP00000593298
resolver
enst
ENST00000270631
resolver
enst
ENST00000923239
resolver
genesymbol
PTH2
resolver
genesymbol_syn
TIP39
resolver
genesymbol_syn
TIPF39
resolver
hgnc
HGNC:30828
resolver
uniprot
Q96DJ4
resolver
uniprot_entry
TIP39_HUMAN
resolver
uniprot_sec
Q96DJ4
resolver
amino_acid_sequence
METRQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPRRSLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP
uniprot
proteins
function
FUNCTION: Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits. {ECO:0000269|PubMed:11861531, ECO:0000269|PubMed:12559132, ECO:0000269|PubMed:12754053, ECO:0000269|PubMed:14988434}.
uniprot
proteins
mass_dalton
11202
uniprot
proteins
protein_family
Parathyroid hormone family
uniprot
proteins
pubmed
11818570
uniprot
proteins
pubmed
11861531
uniprot
proteins
pubmed
12098667
uniprot
proteins
pubmed
12559132
uniprot
proteins
pubmed
12754053
uniprot
proteins
pubmed
14988434
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
100
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins