Tedc1
entrez
104732
canonical
uniprot
Q3UK37
canonical
ensembl
ENSMUSG00000037466
resolver
ensp
ENSMUSP00000035351
resolver
enst
ENSMUST00000049271
resolver
genesymbol
Tedc1
resolver
uniprot
E9Q930
resolver
uniprot
Q3TK97
resolver
uniprot_entry
TEDC1_MOUSE
resolver
uniprot_sec
E9Q930
resolver
uniprot_sec
Q3TK97
resolver
amino_acid_sequence
MRRRRSRVEGAARALPEAVAALSRCLPAGPSPEIFRRAKFDRPEAAPVLWQLLLRVLSPLAANNTWTDLAPEAQACVVKSALGSQGYPRSVLLQFPDGSSQGSRELLLALSWLLARGPLLEQLLAQTRVQLGDQLPQWEAPTSPGPPAPFVEPKSPVDLRLVEWLMGRLRFRWRCLISSQQEQCILLSKIHLYTQGCHSQQSLGHLSVAETEMLRDPESGQQLLQALESENIRLEAALEWRRRELVFWQWMDTVLDTCSPETPAVTSQPTFLPEISEGGLGELESVKQELQALQEELREVSEPRRAAWEARVGGLGQGPEWSNSRKALQEAVQQELAALQGSWEQSSTPGQPQRPHRLVRSKDGAPRPQGLQAAEVIRTLSAKEACLKKALHQLQRQCQQELARLAGALPGLIWILPPEH
uniprot
proteins
function
FUNCTION: Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability (PubMed:29459677). May play a role in counteracting perturbation of actin filaments, such as after treatment with the actin depolymerizing microbial metabolite Chivosazole F (By similarity). {ECO:0000250|UniProtKB:Q86SX3, ECO:0000269|PubMed:29459677}.
uniprot
proteins
mass_dalton
46797
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
29459677
uniprot
proteins
sequence_length
420
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000269|PubMed:29459677}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:29459677}.
uniprot
proteins