Crabp2
entrez
12904
canonical
uniprot
P22935
canonical
ensembl
ENSMUSG00000004885
resolver
ensp
ENSMUSP00000005019
resolver
enst
ENSMUST00000005019
resolver
genesymbol
Crabp2
resolver
uniprot_entry
RABP2_MOUSE
resolver
amino_acid_sequence
MPNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEIKQENDTFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESGNKMVCEQRLLKGEGPKTSWSRELTNDGELILTMTADDVVCTRVYVRE
uniprot
proteins
function
FUNCTION: Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. {ECO:0000269|PubMed:10490651}.
uniprot
proteins
mass_dalton
15746
uniprot
proteins
post_translational_modification
PTM: Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation.
uniprot
proteins
protein_family
Calycin superfamily
uniprot
proteins
protein_family
Fatty-acid binding protein (FABP) family
uniprot
proteins
pubmed
10490651
uniprot
proteins
pubmed
1313808
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2166951
uniprot
proteins
sequence_length
138
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10490651}. Endoplasmic reticulum {ECO:0000250}. Nucleus {ECO:0000269|PubMed:10490651}. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.
uniprot
proteins