DHX35
entrez
60625
canonical
uniprot
Q9H5Z1
canonical
ensembl
ENSG00000101452
resolver
ensp
ENSP00000252011
resolver
ensp
ENSP00000362420
resolver
ensp
ENSP00000657489
resolver
ensp
ENSP00000702632
resolver
ensp
ENSP00000702646
resolver
genesymbol
DHX35
resolver
genesymbol_syn
C20orf15
resolver
genesymbol_syn
DDX35
resolver
hgnc
HGNC:15861
resolver
uniprot
A2RTX3
resolver
uniprot
B4E0J0
resolver
uniprot
F5GXM6
resolver
uniprot
Q5THR0
resolver
uniprot
Q9H4H7
resolver
uniprot
Q9H6T6
resolver
uniprot_entry
DHX35_HUMAN
resolver
uniprot_sec
A2RTX3
resolver
uniprot_sec
B4E0J0
resolver
uniprot_sec
F5GXM6
resolver
uniprot_sec
Q5THR0
resolver
uniprot_sec
Q9H4H7
resolver
uniprot_sec
Q9H6T6
resolver
amino_acid_sequence
MAAPVGPVKFWRPGTEGPGVSISEERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDP
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: Acts as a co-sensor in RIGI-mediated antiviral innate immunity (PubMed:39037956). Enhances RIGI recognition of viral nucleic acids and interacts with RIGI and MAVS to form a signaling complex which triggers downstream signaling cascades that lead to the induction of type I interferons and pro-inflammatory cytokines during the antiviral innate immune response (PubMed:39037956). {ECO:0000269|PubMed:39037956}.
uniprot
proteins
mass_dalton
78910
uniprot
proteins
protein_family
DEAD box helicase family
uniprot
proteins
protein_family
DEAH subfamily
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
11991638
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
39037956
uniprot
proteins
sequence_length
703
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:39037956}. Cytoplasm {ECO:0000269|PubMed:39037956}. Note=Translocates to the cytoplasm upon viral infection. {ECO:0000269|PubMed:39037956}.
uniprot
proteins