Tpgs1
entrez
110012
canonical
uniprot
Q99MS8
canonical
ensembl
ENSMUSG00000020308
resolver
ensp
ENSMUSP00000020552
resolver
ensp
ENSMUSP00000159326
resolver
enst
ENSMUST00000020552
resolver
enst
ENSMUST00000239401
resolver
genesymbol
Tpgs1
resolver
genesymbol_syn
Gm16517
resolver
genesymbol_syn
Gtrgeo22
resolver
uniprot
A0A6Q6PKE1
resolver
uniprot
B2RRP1
resolver
uniprot
Q3U5Q9
resolver
uniprot
Q9R0B5
resolver
uniprot_entry
A0A6Q6PKE1_MOUSE
resolver
uniprot_entry
B2RRP1_MOUSE
resolver
uniprot_entry
TPGS1_MOUSE
resolver
uniprot_sec
Q3U5Q9
resolver
uniprot_sec
Q9R0B5
resolver
amino_acid_sequence
MAALPVPLPPTKMAAVEKRRPAVAPAANFPDSGRTSVSQAAAAAESEEDFLRQLGVTEMLRAALLKVLEIRPEEPIAFLAHYFENMGLRSPTNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRTGMLSCFVLLEFVARAGALFQLLEDPGQAVADRRVGQAVLDTLEGALSAGDMATAPTHYLEAGSRLGPDNLARALDRAASGRRPSVPMAREEFLEKAAALFIAKVKPVG
uniprot
proteins
function
FUNCTION: Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility (PubMed:12242242, PubMed:12972506, PubMed:15890843). May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum. {ECO:0000269|PubMed:12242242, ECO:0000269|PubMed:12972506, ECO:0000269|PubMed:15890843}.
uniprot
proteins
mass_dalton
32626
uniprot
proteins
pubmed
12242242
uniprot
proteins
pubmed
12972506
uniprot
proteins
pubmed
15890843
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
303
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:12972506}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:12972506}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:12972506}. Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000269|PubMed:12972506}. Cell projection, axon {ECO:0000269|PubMed:12972506}. Cell projection, dendrite {ECO:0000269|PubMed:12972506}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:12972506}. Note=Associated with microtubules from neurites, centrosomes, basal bodies and axonemes. {ECO:0000269|PubMed:12972506}.
uniprot
proteins