AFMID
entrez
125061
canonical
uniprot
Q63HM1
canonical
ensembl
ENSG00000183077
resolver
ensp
ENSP00000328938
resolver
ensp
ENSP00000386890
resolver
ensp
ENSP00000527526
resolver
ensp
ENSP00000527527
resolver
ensp
ENSP00000527530
resolver
ensp
ENSP00000527532
resolver
ensp
ENSP00000672123
resolver
ensp
ENSP00000672125
resolver
ensp
ENSP00000672129
resolver
genesymbol
AFMID
resolver
hgnc
HGNC:20910
resolver
uniprot
A2RUB3
resolver
uniprot_entry
KFA_HUMAN
resolver
uniprot_sec
A2RUB3
resolver
amino_acid_sequence
MMDVSGVGFPSKVPWKKMSAEELENQYCPSRWVVRLGAEEALRTYSQIGIEATTRARATRKSLLHVPYGDGEGEKVDIYFPDESSEALPFFLFFHGGYWQSGSKDESAFMVHPLTAQGVAVVIVAYGIAPKGTLDHMVDQVTRSVAFVQKRYPSNKGIYLCGHSAGAHLAAMMLLADWTKHGVTPNLRGFFLVSGVFDLEPIVYTSQNVALQLTLEDAQRNSPQLKVAQAQPVDPTCRVLVVVGQFDSPEFHRQSWEFYQTLCQGEWKASFEELHDVDHFEIVENLTQKDNVLTQIILKTIFQ
uniprot
proteins
ec_number
3.5.1.9
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. {ECO:0000255|HAMAP-Rule:MF_03014}.
uniprot
proteins
mass_dalton
33992
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2. {ECO:0000255|HAMAP-Rule:MF_03014}.
uniprot
proteins
protein_family
Kynurenine formamidase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
303
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000255|HAMAP-Rule:MF_03014}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03014}. Note=Predominantly cytosolic. Some fraction is nuclear. {ECO:0000255|HAMAP-Rule:MF_03014}.
uniprot
proteins