IMP4
entrez
92856
canonical
uniprot
Q96G21
canonical
ensembl
ENSG00000136718
resolver
ensp
ENSP00000259239
resolver
ensp
ENSP00000386716
resolver
ensp
ENSP00000389701
resolver
ensp
ENSP00000409371
resolver
ensp
ENSP00000529497
resolver
ensp
ENSP00000529498
resolver
ensp
ENSP00000621247
resolver
enst
ENST00000259239
resolver
enst
ENST00000428740
resolver
genesymbol
IMP4
resolver
genesymbol_syn
BXDC4
resolver
hgnc
HGNC:30856
resolver
uniprot
E7ENR5
resolver
uniprot
Q3ZTT3
resolver
uniprot_entry
E7ENR5_HUMAN
resolver
uniprot_entry
IMP4_HUMAN
resolver
uniprot_sec
Q3ZTT3
resolver
amino_acid_sequence
MLRREARLRREYLYRKAREEAQRSAQERKERLRRALEENRLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSTE
uniprot
proteins
function
FUNCTION: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). {ECO:0000269|PubMed:12655004, ECO:0000269|PubMed:34516797}.
uniprot
proteins
mass_dalton
33757
uniprot
proteins
pubmed
12655004
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16533400
uniprot
proteins
pubmed
34516797
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:12655004, ECO:0000269|PubMed:16533400, ECO:0000269|PubMed:34516797}.
uniprot
proteins