Slc25a46
entrez
67453
canonical
uniprot
Q9CQS4
canonical
ensembl
ENSMUSG00000024259
resolver
ensp
ENSMUSP00000053325
resolver
enst
ENSMUST00000060396
resolver
genesymbol
Slc25a46
resolver
uniprot
Q3TUD3
resolver
uniprot
Q3UGG7
resolver
uniprot
Q8VDX9
resolver
uniprot_entry
S2546_MOUSE
resolver
uniprot_sec
Q3TUD3
resolver
uniprot_sec
Q3UGG7
resolver
uniprot_sec
Q8VDX9
resolver
amino_acid_sequence
MHPRRPEGFDGLGYRGGVRDDPAFGGPFHARSFGSGTELGHWVTTPPDIPGSRNLHWGEKSPSYGVPSAPPTLEGSAEEPFPGGGEGPRPGPSSEQLNRFAGFGIGLASLFTENVLAHPCIVLRRQCQVNYHARHYHLTPFSIINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGIISEFTPLPREVSHKLNPKQIGEHLLLKCLTYMVAMPFYSASLIETVQSEIIRDNTGILECVKEGIGRVIGLGVPHSKRLLPLFSLIFPTVLHGVLHYIISSIIQKIVLLILKRKTYNSHLAESTSPMQNMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVLPINTQYEGMRDCINTIKQEEGVFGFYKGFGAVIIQYTLHATILQITKMIYSTLLQNSI
uniprot
proteins
function
FUNCTION: Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization. May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane. Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission. {ECO:0000250|UniProtKB:Q96AG3}.
uniprot
proteins
mass_dalton
46224
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
418
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q96AG3}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 103..123; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 314..334; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 382..402; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins