Dpys
entrez
65135
canonical
uniprot
Q63150
canonical
ensembl
ENSRNOG00000004298
resolver
ensp
ENSRNOP00000006004
resolver
enst
ENSRNOT00000006004
resolver
genesymbol
Dpys
resolver
uniprot
Q642F0
resolver
uniprot_entry
DPYS_RAT
resolver
uniprot_sec
Q642F0
resolver
amino_acid_sequence
MAPQERLLIRGGRVVNDDFSQVADVLVEDGVVRALGRDLLPPGDTSRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFHQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLAQDKGVNSFKMFMAYKDLYMVQDQQMYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADAKREGKVVYGEPIAAGLGTDGTQYWNKEWRHAAHHVMGPPLRPDPSTPGFLMNLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPRQPFAEFIYKRVKQRDQTCTPIPVKRAPYKGEVITLKPRETKEDDTAGTRMQGHS
uniprot
proteins
ec_number
3.5.2.2
uniprot
proteins
function
FUNCTION: Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.
uniprot
proteins
mass_dalton
56815
uniprot
proteins
post_translational_modification
PTM: Carboxylation allows a single lysine to coordinate two zinc ions. {ECO:0000250}.
uniprot
proteins
protein_family
Hydantoinase/dihydropyrimidinase family
uniprot
proteins
protein_family
Metallo-dependent hydrolases superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8679696
uniprot
proteins
sequence_length
519
uniprot
proteins