Ppp1r3b
entrez
244416
canonical
uniprot
Q8C767
canonical
ensembl
ENSMUSG00000046794
resolver
ensp
ENSMUSP00000065679
resolver
ensp
ENSMUSP00000147633
resolver
ensp
ENSMUSP00000147736
resolver
ensp
ENSMUSP00000236015
resolver
ensp
ENSMUSP00000236017
resolver
enst
ENSMUST00000070481
resolver
enst
ENSMUST00000210337
resolver
enst
ENSMUST00000211648
resolver
genesymbol
Ppp1r3b
resolver
genesymbol_syn
Ppp1r4
resolver
uniprot
Q6PAJ7
resolver
uniprot_entry
PPR3B_MOUSE
resolver
uniprot_sec
Q6PAJ7
resolver
amino_acid_sequence
MAVDIQYSYSSMAPSLRRERFTFKISPKLSKPLRPCIQLGSKDEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDIPFNITELLDNIVSLTTAESESFVLDFPQPSADYLDFRNRLQTNHVCLENCVLKDKAIAGTVKVQNLAFEKVVKIRMTFDTWKSFTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVCYECNGQAYWDSNKGKNYRITRAELRSSPGKIEPYNGPDFGISFDQFGSPRCSFGLFPEWPSYLGYEKLGPYY
uniprot
proteins
function
FUNCTION: Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
32433
uniprot
proteins
pubmed
11872655
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16949035
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
284
uniprot
proteins