PPM1L
entrez
151742
canonical
uniprot
Q5SGD2
canonical
ensembl
ENSG00000163590
resolver
ensp
ENSP00000295839
resolver
ensp
ENSP00000417659
resolver
ensp
ENSP00000420746
resolver
genesymbol
PPM1L
resolver
genesymbol_syn
PP2CE
resolver
hgnc
HGNC:16381
resolver
uniprot
Q2M3J2
resolver
uniprot
Q96NM7
resolver
uniprot_entry
PPM1L_HUMAN
resolver
uniprot_sec
Q2M3J2
resolver
uniprot_sec
Q96NM7
resolver
amino_acid_sequence
MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKNHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6. {ECO:0000269|PubMed:17456047}.
uniprot
proteins
mass_dalton
41053
uniprot
proteins
protein_family
PP2C family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15560375
uniprot
proteins
pubmed
17456047
uniprot
proteins
sequence_length
360
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..42; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins