Aldh1a3
entrez
266603
canonical
uniprot
Q8K4D8
canonical
ensembl
ENSRNOG00000052070
resolver
ensp
ENSRNOP00000069212
resolver
ensp
ENSRNOP00000087440
resolver
enst
ENSRNOT00000085158
resolver
enst
ENSRNOT00000098068
resolver
genesymbol
Aldh1a3
resolver
genesymbol_syn
Aldh6
resolver
genesymbol_syn
Raldh3
resolver
uniprot
A0A0G2JUS6
resolver
uniprot
A0A8I6A4D2
resolver
uniprot
A0A9K3Y6M8
resolver
uniprot
B2GUU8
resolver
uniprot_entry
A0A8I6A4D2_RAT
resolver
uniprot_entry
A0A9K3Y6M8_RAT
resolver
uniprot_entry
AL1A3_RAT
resolver
uniprot_entry
B2GUU8_RAT
resolver
uniprot_sec
A0A0G2JUS6
resolver
amino_acid_sequence
MATANGAVENGQPDGKPPALPRPIRNLEVKFTKIFINNDWHEPKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLIERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVMCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGRNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWVNCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLDEKNP
uniprot
proteins
ec_number
1.2.1.36
uniprot
proteins
function
FUNCTION: Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively (Probable). High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity (By similarity). Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions; a critical lipid in the embryonic development of the eye and the nasal region (By similarity). {ECO:0000250|UniProtKB:P47895, ECO:0000250|UniProtKB:Q9JHW9, ECO:0000305|PubMed:12390888}.
uniprot
proteins
mass_dalton
56171
uniprot
proteins
pathway_participation
PATHWAY: Cofactor metabolism; retinol metabolism. {ECO:0000250|UniProtKB:P47895}.
uniprot
proteins
protein_family
Aldehyde dehydrogenase family
uniprot
proteins
pubmed
12390888
uniprot
proteins
sequence_length
512
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9JHW9}.
uniprot
proteins