A3galt2
entrez
171553
canonical
uniprot
A0A4Z3
canonical
ensembl
ENSRNOG00000005935
resolver
ensembl
ENSRNOG00055028687
resolver
ensembl
ENSRNOG00060016470
resolver
ensembl
ENSRNOG00065031329
resolver
ensp
ENSRNOP00000111458
resolver
ensp
ENSRNOP00055040851
resolver
ensp
ENSRNOP00060022759
resolver
ensp
ENSRNOP00065044444
resolver
enst
ENSRNOT00000126249
resolver
enst
ENSRNOT00055049651
resolver
enst
ENSRNOT00060028244
resolver
enst
ENSRNOT00065054014
resolver
genesymbol
A3galt2
resolver
uniprot
A2JQW1
resolver
uniprot_entry
A3LT2_RAT
resolver
uniprot_sec
A2JQW1
resolver
amino_acid_sequence
MALEGLRAKKRLLWRLFLSAFGLLGLYHYWFKIFRLFEVFIPMGICPMAIMPLLKDNFTGVLRHWARPEVLTCTSWGAPIIWDETFDPHVAEREARRQNLTIGLTVFAVGRYLEKYLEHFLVSAEQYFMVGQNVVYYVFTDRPEAVPHVALGQGRLLRVKPVRREKRWQDVSMARMLTLHEALGGQLGREADYVFCLDVDQYFSGNFGPEVLADLVAQLHAWHFRWPRWMLPYERDKRSAAALSLSEGDFYYHAAVFGGSVAALLKLTAHCATGQQLDREHGIEARWHDESHLNKFFWLSKPTKLLSPEFCWAEEIGWRPEIHHPRLIWAPKEYALVRT
uniprot
proteins
ec_number
2.4.1.87
uniprot
proteins
function
FUNCTION: Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo-series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and is solely responsible for initiating the synthesis of isoglobo-series glycosphingolipids. {ECO:0000269|PubMed:10854427, ECO:0000269|PubMed:12626403, ECO:0000269|PubMed:17206613}.
uniprot
proteins
mass_dalton
39548
uniprot
proteins
mutagenesis
MUTAGEN 187; /note="L->P: Significant loss of activity."; /evidence="ECO:0000269|PubMed:18630988"; MUTAGEN 198..200; /note="DVD->AVA: Catalytically inactive."; /evidence="ECO:0000269|PubMed:10854427"; MUTAGEN 252; /note="Y->N: Complete loss of activity."; /evidence="ECO:0000269|PubMed:18630988
uniprot
proteins
protein_family
Glycosyltransferase 6 family
uniprot
proteins
pubmed
10854427
uniprot
proteins
pubmed
12626403
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17206613
uniprot
proteins
pubmed
18630988
uniprot
proteins
sequence_length
339
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:17206613, ECO:0000269|PubMed:18630988}; Single-pass type II membrane protein {ECO:0000269|PubMed:17206613, ECO:0000269|PubMed:18630988}. Note=Also found in numerous large vesicles throughout the cytoplasm of the soma.
uniprot
proteins
transmembrane_region
TRANSMEM 12..31; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins