Sulf1
entrez
171396
canonical
uniprot
Q8VI60
canonical
ensembl
ENSRNOG00000009037
resolver
ensembl
ENSRNOG00055017510
resolver
ensembl
ENSRNOG00060001963
resolver
ensembl
ENSRNOG00065010873
resolver
ensp
ENSRNOP00000064072
resolver
ensp
ENSRNOP00055023787
resolver
ensp
ENSRNOP00060002058
resolver
ensp
ENSRNOP00065013551
resolver
enst
ENSRNOT00000072411
resolver
enst
ENSRNOT00055029624
resolver
enst
ENSRNOT00060003072
resolver
enst
ENSRNOT00065017652
resolver
genesymbol
Sulf1
resolver
uniprot
A0A8J8YBA4
resolver
uniprot_entry
A0A8J8YBA4_RAT
resolver
uniprot_entry
SULF1_RAT
resolver
amino_acid_sequence
MKNSCWALLLAVLGAELLGGFCSTMRSQRFRGRVQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFTNAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQALHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNVLQRKRLQTLMSVDDSVERLYNMLVETGELGNTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSIEPGSIVPQIVLNIDLAPTILDIAGLDTPSDVDGKSVLKLLDLEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQNWQCIEDTSGKLRIHKCKGPSDLLTVRQNARNLYSRGLQDKDKECHCRESGYRPSRSQRKKERQFLRNQGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEELQVLPPRSVAKRHDEGHQGFGGHQAAAGDFRNEMLADSNSAVGLPTTVRVTHKCFILPNDTIHCERELYQSARAWKDHKAYIDKEIEVLQDKIKNLREVRGHLKKRKPEECSCGKQSYYNKEKGVKRQEKLKSHLHPFKEAAAQEVDSKLQLFKEHRRRKKERKEKKRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHIQLMELRSCQGYKQCNPRPKSLDVGTKEGGNYDPHRGQLWDGWEG
uniprot
proteins
ec_number
3.1.6.1
uniprot
proteins
ec_number
3.1.6.14
uniprot
proteins
function
FUNCTION: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (By similarity). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin (By similarity). Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation (By similarity). {ECO:0000250|UniProtKB:Q8IWU6}.
uniprot
proteins
mass_dalton
100860
uniprot
proteins
post_translational_modification
PTM: Processing by furin produces a secreted form. {ECO:0000250|UniProtKB:Q8IWU6}.; PTM: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. {ECO:0000250|UniProtKB:P15289}.
uniprot
proteins
protein_family
Sulfatase family
uniprot
proteins
pubmed
11895481
uniprot
proteins
sequence_length
870
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:11895481}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:11895481}. Cell surface {ECO:0000269|PubMed:11895481}.; SUBCELLULAR LOCATION: [Extracellular sulfatase Sulf-2 secreted form]: Secreted {ECO:0000250|UniProtKB:Q8IWU6}.
uniprot
proteins