SERINC2
entrez
347735
canonical
uniprot
Q96SA4
canonical
ensembl
ENSG00000168528
resolver
ensp
ENSP00000362813
resolver
ensp
ENSP00000362814
resolver
ensp
ENSP00000439048
resolver
ensp
ENSP00000444307
resolver
genesymbol
SERINC2
resolver
genesymbol_syn
TDE2L
resolver
hgnc
HGNC:23231
resolver
uniprot
A0AVB4
resolver
uniprot
B4DJK5
resolver
uniprot
B7Z567
resolver
uniprot
B7ZAP2
resolver
uniprot
E7EUZ9
resolver
uniprot
Q86Y23
resolver
uniprot
Q96IM8
resolver
uniprot_entry
Q96IM8_HUMAN
resolver
uniprot_entry
SERC2_HUMAN
resolver
uniprot_sec
A0AVB4
resolver
uniprot_sec
B4DJK5
resolver
uniprot_sec
B7Z567
resolver
uniprot_sec
B7ZAP2
resolver
uniprot_sec
E7EUZ9
resolver
uniprot_sec
Q86Y23
resolver
amino_acid_sequence
MGACLGACSLLSCASCLCGSAPCILCSCCPASRNSTVSRLIFTFFLFLGVLVSIIMLSPGVESQLYKLPWVCEEGAGIPTVLQGHIDCGSLLGYRAVYRMCFATAAFFFFFTLLMLCVSSSRDPRAAIQNGFWFFKFLILVGLTVGAFYIPDGSFTNIWFYFGVVGSFLFILIQLVLLIDFAHSWNQRWLGKAEECDSRAWYAGLFFFTLLFYLLSIAAVALMFMYYTEPSGCHEGKVFISLNLTFCVCVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSIPEQKCNPHLPTQLGNETVVAGPEGYETQWWDAPSIVGLIIFLLCTLFISLRSSDHRQVNSLMQTEECPPMLDATQQQQQVAACEGRAFDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYKPGETRKMISTWTAVWVKICASWAGLLLYLWTLVAPLLLRNRDFS
uniprot
proteins
function
FUNCTION: Non-ATP-dependent, non-specific lipid transporter for phosphatidylserine, phosphatidylcholine, and phosphatidylethanolamine. Functions as a scramblase that flips lipids in both directions across the membrane. In contrast to SERINC3 and SERINC5, has no effect on HIV-1 particles infectivity. {ECO:0000269|PubMed:37474505}.
uniprot
proteins
mass_dalton
50742
uniprot
proteins
protein_family
TDE1 family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
37474505
uniprot
proteins
sequence_length
455
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 5..27; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 40..57; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 96..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 160..182; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..224; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 239..256; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 268..290; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 317..339; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 385..407; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 422..444; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins