Fam20a
entrez
208659
canonical
uniprot
Q8CID3
canonical
ensembl
ENSMUSG00000020614
resolver
ensp
ENSMUSP00000020938
resolver
ensp
ENSMUSP00000116687
resolver
enst
ENSMUST00000020938
resolver
enst
ENSMUST00000155559
resolver
genesymbol
Fam20a
resolver
uniprot_entry
FA20A_MOUSE
resolver
amino_acid_sequence
MPGLRRDRLLALLLLGALFSADLYFHLWPQVQRQLRPGERPAACPCSGRAPSASLHSAAASRDLGTASHNFSGALPRVEHPSRGHPAPRSKLQALFAHSLYQVLEDPPLLGPEDWLLASQEALRYYRRKVARWNRRHKIYKEQFNLTSLDPPLQFRPEASWVQFHLGINSHGLYSRSSLAISKLLHDMRHFPTISADYSQDEKALLGACDCSQIVKPSGVHLKLVLRFSDFGKAMFKPMRQQREEETPEDFFYFIDFQRHNAEIAAFHLDRILDFRRVPPTVGRLVNVTKEILEVTKNEILQSVFFVSPANNVCFFAKCPYMCKTEYAVCGNPHLLEGSLSAFLPSLNLAPRLSVPNPWIRSYSLSGKEEWELNPLYCDTVKQIYPYNSSNRLLGIIDMAVFDFLIGNMDRHHYEMFTKFGDDGYLIHLDNARGFGRHSQDEISILAPLAQCCMIKRKTLLHLQLLAQADYRLSDVMRESLLEDQLSPVLTEPHLLALDRRLQIILKTVEDCIEAHGERRVIAEGSAQRSAPDSGQANLTS
uniprot
proteins
function
FUNCTION: Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. {ECO:0000269|PubMed:25789606}.
uniprot
proteins
mass_dalton
61526
uniprot
proteins
mutagenesis
MUTAGEN 14..15; /note="LL->DE: Not secreted; nuclear localization."; /evidence="ECO:0000269|PubMed:15676076
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:15676076}.
uniprot
proteins
protein_family
FAM20 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15676076
uniprot
proteins
pubmed
21549343
uniprot
proteins
pubmed
22732358
uniprot
proteins
pubmed
22900076
uniprot
proteins
pubmed
25789606
uniprot
proteins
pubmed
29858230
uniprot
proteins
sequence_length
541
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15676076}. Golgi apparatus {ECO:0000269|PubMed:22900076}. Endoplasmic reticulum {ECO:0000269|PubMed:22900076}.
uniprot
proteins