Dr1
entrez
13486
canonical
uniprot
Q91WV0
canonical
ensembl
ENSMUSG00000029265
resolver
ensp
ENSMUSP00000031190
resolver
enst
ENSMUST00000031190
resolver
genesymbol
Dr1
resolver
uniprot
Q3UT14
resolver
uniprot_entry
NC2B_MOUSE
resolver
uniprot_sec
Q3UT14
resolver
amino_acid_sequence
MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASTQAGSSQDEEDDDDI
uniprot
proteins
function
FUNCTION: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
19431
uniprot
proteins
post_translational_modification
PTM: Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1 (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
NC2 beta/DR1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
176
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins