Snx19
entrez
102607
canonical
uniprot
Q6P4T1
canonical
ensembl
ENSMUSG00000031993
resolver
ensp
ENSMUSP00000131895
resolver
ensp
ENSMUSP00000311405
resolver
ensp
ENSMUSP00000311406
resolver
ensp
ENSMUSP00000311410
resolver
ensp
ENSMUSP00000311414
resolver
ensp
ENSMUSP00000311415
resolver
ensp
ENSMUSP00000311416
resolver
enst
ENSMUST00000164099
resolver
genesymbol
Snx19
resolver
genesymbol_syn
Kiaa0254
resolver
uniprot
Q3TQ83
resolver
uniprot
Q80U53
resolver
uniprot_entry
SNX19_MOUSE
resolver
uniprot_sec
Q3TQ83
resolver
uniprot_sec
Q80U53
resolver
amino_acid_sequence
MKAQTVSPTQGTISESSYVHSNLWSSRKLMIVGVLVGWLLVIHLLVNMWLLILLCASLVALGGWLGSTAILGASGQLHLERFITITTCPPCPEAERQLEQEINRTIQMIIRDFVLSWYRSVSHEPAFEAEMEAAMKGLVQELRRRMSIVDSHALTQRVLTLCGCHLQSYIQAKEATAKEQSCPVQPSQLWDAYCQVTAPHPAMSCPTTEVTYARGIVNLILKELVPKPHLETRTGRHVVVEVITCNVILPLISKLSDPDWIHLILVSIFSKYRHDAAQGTKPPCSSSVLEQPSVPTSLPLIVEVESLPVGKASSPATAPVHLTSSEPAPSPEIEEGHEAVEGDLPGMLEEKKVGNSSSHFLQPDIRGPLFLCEDSELESPLSELSKETILLMTPGNFLSDRIQDALCALDDSGALEPKDGEGSECMEGAEAEEAPGTDTETGMLVSVLNCPEIQIDTADKEVEQGDDTSLTALLEEPEKPCPLRPSCLDKDLASGVCSLEPAMPPVPLSSSPPGPLSSATFSFESLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETVLNGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIGNSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKASKSRLRFSSSKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLRIQPAEVPDKDPQQVPKEYVDSGLLDKAVVAQELNKSGPGTETELADTAFDLILLLLMEQWKWLCTESMQKFLHIIFGTLVQRWLEVQVANLTCPQRWAQYLHLLRESIWPGGVLPKFPRPGRTQAQKAATEKQALQSLMDLLPDFLVEILGVNKCRLSWSLVLESFQQPLINRHLIYCLGDIILELLDLSASVEECAPATSASDSPGSLKKMAVST
uniprot
proteins
function
FUNCTION: Plays a role in intracellular vesicle trafficking and exocytosis (PubMed:24843546). May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion (PubMed:24843546). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:25148684). {ECO:0000269|PubMed:24843546, ECO:0000269|PubMed:25148684}.
uniprot
proteins
mass_dalton
109808
uniprot
proteins
mutagenesis
MUTAGEN 587; /note="R->A: Abolishes location on endosome membranes."; /evidence="ECO:0000269|PubMed:25148684"; MUTAGEN 587; /note="R->Q: Abolishes interaction with membranes enriched in phosphatidylinositol 3-phosphate."; /evidence="ECO:0000269|PubMed:25148684"; MUTAGEN 634; /note="R->K: Abolishes interaction with membranes enriched in phosphatidylinositol 3-phosphate. Abolishes location on endosome membranes."; /evidence="ECO:0000269|PubMed:25148684
uniprot
proteins
protein_family
Sorting nexin family
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24843546
uniprot
proteins
pubmed
25148684
uniprot
proteins
sequence_length
997
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Early endosome membrane {ECO:0000305|PubMed:25148684}; Peripheral membrane protein {ECO:0000269|PubMed:25148684}; Cytoplasmic side {ECO:0000269|PubMed:25148684}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:25148684}; Peripheral membrane protein {ECO:0000269|PubMed:25148684}; Cytoplasmic side {ECO:0000269|PubMed:25148684}.
uniprot
proteins