Atf7ip2
entrez
75329
canonical
uniprot
Q3UL97
canonical
ensembl
ENSMUSG00000039200
resolver
ensp
ENSMUSP00000036731
resolver
ensp
ENSMUSP00000113480
resolver
ensp
ENSMUSP00000338409
resolver
genesymbol
Atf7ip2
resolver
genesymbol_syn
Mcaf2
resolver
genesymbol_syn
Psm2
resolver
uniprot
Q3UT16
resolver
uniprot
Q4VIF3
resolver
uniprot
Q8BPC5
resolver
uniprot
Q9D4T8
resolver
uniprot_entry
MCAF2_MOUSE
resolver
uniprot_sec
Q3UT16
resolver
uniprot_sec
Q4VIF3
resolver
uniprot_sec
Q8BPC5
resolver
uniprot_sec
Q9D4T8
resolver
amino_acid_sequence
MESPDRKRQKVLKAKKTMPTSYQKQLEILNKSTNVEAPKTTVGTNIPNGHNQKMFSKNKENVKVMKVSEQINENACGALERHTALLEQVKHWIRQEICMINCNLFDKKLNELNERIGKTQCKSRHEAIAGELFVKIRRLQKRIKTVLSSQRNCLEPNTLPSNTVCKVTDSEAMNLNVTQKSVKSRSKRISSVNHTPLNSSEKAGRKTNLPSTCVEFASESNTDDVMLISVKNSNLTTSITSEQTEIRKNTSRNLSNSPNSMIKVGPVEKKFDFVIDLTREGPSNYSIESPSFTLKSTSKAVLRSKEIIPVAENGNEGFGSFEHLPPLPEPPAPLPEMADKIKDTLPPQKPELKVKWVLRPTSIALTWNIPKVNPNCAPVESYHLFLYYENSDHLTWKKIAEIKALPLPMACTLSQNLASTKYYFAVQSKDIFGRYGPFCNIKSIPRFSENLT
uniprot
proteins
function
FUNCTION: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
50975
uniprot
proteins
protein_family
MCAF family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16850184
uniprot
proteins
sequence_length
452
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins