INPP1
entrez
3628
canonical
uniprot
P49441
canonical
ensembl
ENSG00000151689
resolver
ensp
ENSP00000325423
resolver
ensp
ENSP00000376142
resolver
ensp
ENSP00000559823
resolver
ensp
ENSP00000559826
resolver
ensp
ENSP00000559829
resolver
ensp
ENSP00000559830
resolver
ensp
ENSP00000559832
resolver
ensp
ENSP00000559833
resolver
ensp
ENSP00000559834
resolver
ensp
ENSP00000559835
resolver
ensp
ENSP00000559836
resolver
ensp
ENSP00000559837
resolver
ensp
ENSP00000596947
resolver
ensp
ENSP00000596948
resolver
ensp
ENSP00000626216
resolver
ensp
ENSP00000626217
resolver
ensp
ENSP00000626218
resolver
ensp
ENSP00000626219
resolver
ensp
ENSP00000626220
resolver
ensp
ENSP00000626221
resolver
ensp
ENSP00000626222
resolver
ensp
ENSP00000626223
resolver
ensp
ENSP00000626224
resolver
enst
ENST00000322522
resolver
enst
ENST00000392329
resolver
enst
ENST00000889764
resolver
enst
ENST00000889767
resolver
enst
ENST00000889770
resolver
enst
ENST00000889771
resolver
enst
ENST00000889773
resolver
enst
ENST00000889774
resolver
enst
ENST00000889775
resolver
enst
ENST00000889776
resolver
enst
ENST00000889777
resolver
enst
ENST00000889778
resolver
enst
ENST00000926888
resolver
enst
ENST00000926889
resolver
enst
ENST00000956157
resolver
enst
ENST00000956158
resolver
enst
ENST00000956159
resolver
enst
ENST00000956160
resolver
enst
ENST00000956161
resolver
enst
ENST00000956162
resolver
enst
ENST00000956163
resolver
enst
ENST00000956164
resolver
enst
ENST00000956165
resolver
genesymbol
INPP1
resolver
hgnc
HGNC:6071
resolver
uniprot
D3DPI6
resolver
uniprot
Q6IBG4
resolver
uniprot_entry
INPP_HUMAN
resolver
uniprot_entry
Q6IBG4_HUMAN
resolver
uniprot_sec
D3DPI6
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by Li(+). {ECO:0000250|UniProtKB:P21327}.
uniprot
proteins
amino_acid_sequence
MSDILRELLCVSEKAANIARACRQQEALFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEESNEFTNDWGEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIWVDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAAFSPSFSAVISTSEKETIKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAHAILRAMGGGIVDLKECLERNPETGLDLPQLVYHVENEGAAGVDRWANKGGLIAYRSRKRLETFLSLLVQNLAPAETHT
uniprot
proteins
ec_number
3.1.3.57
uniprot
proteins
function
FUNCTION: Mg(2+)-dependent phosphatase that catalyzes the hydrolysis of the 1-position phosphate from inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate and participates in inositol phosphate metabolism. {ECO:0000269|PubMed:8390685}.
uniprot
proteins
mass_dalton
43998
uniprot
proteins
pathway_participation
PATHWAY: Signal transduction; phosphatidylinositol signaling pathway. {ECO:0000250|UniProtKB:P21327}.
uniprot
proteins
protein_family
Inositol monophosphatase superfamily
uniprot
proteins
pubmed
10780272
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8390685
uniprot
proteins
pubmed
9682271
uniprot
proteins
sequence_length
399
uniprot
proteins