Fhl2
entrez
63839
canonical
uniprot
O35115
canonical
ensembl
ENSRNOG00000016866
resolver
ensembl
ENSRNOG00065029634
resolver
ensp
ENSRNOP00000084804
resolver
ensp
ENSRNOP00000088694
resolver
ensp
ENSRNOP00065042111
resolver
enst
ENSRNOT00000101412
resolver
enst
ENSRNOT00065051169
resolver
genesymbol
Fhl2
resolver
genesymbol_syn
Dral
resolver
genesymbol_syn
Slim3
resolver
uniprot_entry
FHL2_RAT
resolver
amino_acid_sequence
MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYRDQPWHRECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
uniprot
proteins
function
FUNCTION: May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation (By similarity). Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:22851699). {ECO:0000250|UniProtKB:Q14192, ECO:0000269|PubMed:22851699}.
uniprot
proteins
mass_dalton
32087
uniprot
proteins
pubmed
11001931
uniprot
proteins
pubmed
11813260
uniprot
proteins
pubmed
22851699
uniprot
proteins
sequence_length
279
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q14192}. Nucleus {ECO:0000250|UniProtKB:Q14192}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:22851699}.
uniprot
proteins