AKIRIN1
entrez
79647
canonical
uniprot
Q9H9L7
canonical
ensembl
ENSG00000174574
resolver
ensp
ENSP00000389866
resolver
ensp
ENSP00000392678
resolver
genesymbol
AKIRIN1
resolver
genesymbol_syn
C1orf108
resolver
hgnc
HGNC:25744
resolver
uniprot
B4DZU6
resolver
uniprot
Q0VDB3
resolver
uniprot
Q53FK8
resolver
uniprot_entry
AKIR1_HUMAN
resolver
uniprot_sec
B4DZU6
resolver
uniprot_sec
Q0VDB3
resolver
uniprot_sec
Q53FK8
resolver
amino_acid_sequence
MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPPDAEPPPPFQTQTPPQSLQQPAPPGSERRLPTPEQIFQNIKQEYSRYQRWRHLEVVLNQSEACASESQPHSSALTAPSSPGSSWMKKDQPTFTLRQVGIICERLLKDYEDKIREEYEQILNTKLAEQYESFVKFTHDQIMRRYGTRPTSYVS
uniprot
proteins
function
FUNCTION: Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development (By similarity). Functions as a signal transducer for MSTN during skeletal muscle regeneration and myogenesis (By similarity). May regulate chemotaxis of both macrophages and myoblasts by reorganising actin cytoskeleton, leading to more efficient lamellipodia formation via a PI3 kinase dependent pathway (By similarity). In contrast to AKIRIN2, not involved in nuclear import of proteasomes (PubMed:34711951). {ECO:0000250|UniProtKB:Q99LF1, ECO:0000269|PubMed:34711951}.
uniprot
proteins
mass_dalton
21867
uniprot
proteins
protein_family
Akirin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
18066067
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
34711951
uniprot
proteins
sequence_length
192
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:18066067}.
uniprot
proteins