Fam162a
entrez
360721
canonical
uniprot
Q4QQV3
canonical
ensembl
ENSRNOG00000002255
resolver
ensp
ENSRNOP00000081032
resolver
ensp
ENSRNOP00000096204
resolver
enst
ENSRNOT00000099640
resolver
enst
ENSRNOT00000116350
resolver
genesymbol
Fam162a
resolver
genesymbol_syn
E2ig5
resolver
uniprot
A0A8I5ZR27
resolver
uniprot_entry
A0A8I5ZR27_RAT
resolver
uniprot_entry
F162A_RAT
resolver
amino_acid_sequence
MWSLRGLRLAAGHCFRLCERNVSSPLRLTRNTDLKRINGFCTKPQESPKAPTQSYRHRVPLHKPTDFEKKILLWSGRFKKEEEIPETISFEMLDAAKNKIRVKVSYLMIALTVAGCVYMVIEGKKAAKRHESLTSLNLERKARLREEAAMKAKAD
uniprot
proteins
function
FUNCTION: Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly. {ECO:0000250|UniProtKB:Q9D6U8}.
uniprot
proteins
mass_dalton
17827
uniprot
proteins
protein_family
UPF0389 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19520982
uniprot
proteins
pubmed
32272861
uniprot
proteins
sequence_length
155
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:Q96A26}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 102..121; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins