Cbx8
entrez
30951
canonical
uniprot
Q9QXV1
canonical
ensembl
ENSMUSG00000025578
resolver
ensp
ENSMUSP00000026663
resolver
enst
ENSMUST00000026663
resolver
genesymbol
Cbx8
resolver
genesymbol_syn
Pc3
resolver
uniprot_entry
CBX8_MOUSE
resolver
amino_acid_sequence
MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSTRGIRIPYPGRSPQDLASTSRAREGLRNTGLPPPGSSTSTCRADPPRDRDRERDRGTSRVDDKPSSPGDSSKKRGPKPRKEPLDPSQRPLGEPSAGLGEYLKGRKLDETSSGTGKFPAGHSVIQLARRQDSDLVQYGVTSPSSAEASSKLAVDTFPARVIKHRAAFLEAKGQGALDPGGARVRHSSGTPASVGSLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR
uniprot
proteins
function
FUNCTION: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity). {ECO:0000250|UniProtKB:Q9HC52}.
uniprot
proteins
mass_dalton
39860
uniprot
proteins
pubmed
10721694
uniprot
proteins
pubmed
11439343
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16359901
uniprot
proteins
pubmed
16537902
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
362
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16537902}. Chromosome {ECO:0000269|PubMed:16537902}. Note=Localizes to the inactivated X chromosome in females. {ECO:0000269|PubMed:16537902}.
uniprot
proteins