Lcmt2
entrez
329504
canonical
uniprot
Q8BYR1
canonical
ensembl
ENSMUSG00000074890
resolver
ensp
ENSMUSP00000106302
resolver
genesymbol
Lcmt2
resolver
genesymbol_syn
Kiaa0547
resolver
genesymbol_syn
Tyw4
resolver
uniprot
A2ART9
resolver
uniprot
Q3T9F7
resolver
uniprot
Q6A048
resolver
uniprot
Q8BIG6
resolver
uniprot_entry
TYW4_MOUSE
resolver
uniprot_sec
A2ART9
resolver
uniprot_sec
Q3T9F7
resolver
uniprot_sec
Q6A048
resolver
uniprot_sec
Q8BIG6
resolver
amino_acid_sequence
MGPRGRQRRAGTVQSTNDSSSLSKRSLAAHGYVRDPFAALLVPGPVRRTPLIHRGYYVRARAVRHCVRAFLELTSALPSRTRAQILSLGSGSDSLYFRLKAAGLLARAAVWEVDFPDVSRLKAERIEETPELRAQTGPFKIGDSASSLCFESADYRILGADLRELQRLGEALDGAGLDATSPTLLLAEAVLTYLEPSSATALIAWAAQRFPDALFVIYEQMQPGDAFGQIMLQHFQRLHSPLHGLELFPVVKAQRQRFLQAGWTACSALDLNEFYRRLLSAEERQRVETLEPFDEYEEWHLKCSHYFILAASRGDILSETPVFEPSEASFQIDPASPSGFLSARVVTSDHQHSSLKRYGHASALLSPGVIFSAGGFGEQEGRHCRVSRFHVLSRSCDSEWEGCQISTLGTEGQWDGRLYHTMTRLSDTRVLVLGGRLSPVSPASGALQLDLYKSKDNCSEGQNVTVTKAALEEGSVLSCWRHSTTEVYYQNQRYLFVYGGRSVAEPVLSDCRFLHVETMAWVRIPVQGASPEGRHSHSACSWQGGALIAGGLGASEELLSSVLFLKPVSSGFLWESIDIQPSITPRYSHTAHVFNGKLLLVGGVWIHSSSVPGVTVICLTTGLSSEYQIDTASVPWPLMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVALDLSSLRSGQ
uniprot
proteins
ec_number
2.1.1.290
uniprot
proteins
ec_number
2.3.1.231
uniprot
proteins
function
FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the final 2 independent reactions, methylation of the alpha-carboxy group of wybutosine-72 to form wybutosine-58, and methoxycarbonylation of alpha-amino group of wybutosine-58 through the fixation of CO(2) to complete wybutosine. {ECO:0000250|UniProtKB:Q08282}.
uniprot
proteins
mass_dalton
75295
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
uniprot
proteins
protein_family
LCMT family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
686
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q08282}.
uniprot
proteins