Atp6v1b1
entrez
110935
canonical
uniprot
Q91YH6
canonical
ensembl
ENSMUSG00000006269
resolver
ensp
ENSMUSP00000006431
resolver
enst
ENSMUST00000006431
resolver
genesymbol
Atp6v1b1
resolver
genesymbol_syn
Atp6b1
resolver
uniprot
Q6P6I3
resolver
uniprot
Q8C3L6
resolver
uniprot_entry
VATB1_MOUSE
resolver
uniprot_sec
Q6P6I3
resolver
uniprot_sec
Q8C3L6
resolver
amino_acid_sequence
MATTVDSRSSGFTGNSCDPGTAQEHVQAVTRNYITHPRVTYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDSQKTTCEFTGDILRTPVSEDMLGRIFNGSGKPIDKGPAVMAEEFLDINGQPINPHDRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHEDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQVYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFITQGPYENRTVFESLDLGWKLLRIFPKEMLKRIPQSMTDEFYSRQGAQQDPASDTAL
uniprot
proteins
function
FUNCTION: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:16174750, PubMed:23028982). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Essential for the proper assembly and activity of V-ATPase (By similarity). In renal intercalated cells, mediates secretion of protons (H+) into the urine thereby ensuring correct urinary acidification (PubMed:16174750). Required for optimal olfactory function by mediating the acidification of the nasal olfactory epithelium (PubMed:23028982). {ECO:0000250|UniProtKB:P15313, ECO:0000269|PubMed:16174750, ECO:0000269|PubMed:23028982}.
uniprot
proteins
mass_dalton
56791
uniprot
proteins
protein_family
ATPase alpha/beta chains family
uniprot
proteins
pubmed
14585495
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16174750
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23028982
uniprot
proteins
pubmed
29993276
uniprot
proteins
sequence_length
513
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:23028982, ECO:0000269|PubMed:29993276}. Basolateral cell membrane {ECO:0000269|PubMed:23028982}.
uniprot
proteins