Cers4
entrez
67260
canonical
uniprot
Q9D6J1
canonical
ensembl
ENSMUSG00000008206
resolver
ensp
ENSMUSP00000008350
resolver
ensp
ENSMUSP00000288508
resolver
ensp
ENSMUSP00000288511
resolver
ensp
ENSMUSP00000288513
resolver
ensp
ENSMUSP00000288515
resolver
enst
ENSMUST00000008350
resolver
genesymbol
Cers4
resolver
genesymbol_syn
Lass4
resolver
genesymbol_syn
Trh1
resolver
uniprot
Q8BZA6
resolver
uniprot
Q8C151
resolver
uniprot
Q9CX09
resolver
uniprot_entry
CERS4_MOUSE
resolver
uniprot_sec
Q8BZA6
resolver
uniprot_sec
Q8C151
resolver
uniprot_sec
Q9CX09
resolver
amino_acid_sequence
MSFSLSEWLWQETYWLPPNVTWAELEDRDGLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQCPEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILYHESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLPFDVKRKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDALFIMFALVFFYTRLIFFPTQVIYTSVYDSIKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRSDVEEPDSSDDEPVSEGPQLKNGMARGSRVAVTNGPRSRAAACLTNGHTRAT
uniprot
proteins
ec_number
2.3.1.-
uniprot
proteins
ec_number
2.3.1.24
uniprot
proteins
function
FUNCTION: Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor. {ECO:0000269|PubMed:12912983, ECO:0000269|PubMed:15823095}.
uniprot
proteins
mass_dalton
46017
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; sphingolipid metabolism. {ECO:0000269|PubMed:12912983, ECO:0000269|PubMed:15823095}.
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at the C-terminus by CK2. {ECO:0000250|UniProtKB:Q9HA82}.
uniprot
proteins
protein_family
Sphingosine N-acyltransferase family
uniprot
proteins
pubmed
12912983
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15823095
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
393
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12912983}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 32..52; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 140..160; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 217..237; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 265..285; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 304..324; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins