Fgf21
entrez
56636
canonical
uniprot
Q9JJN1
canonical
ensembl
ENSMUSG00000030827
resolver
ensp
ENSMUSP00000033099
resolver
enst
ENSMUST00000033099
resolver
genesymbol
Fgf21
resolver
uniprot_entry
FGF21_MOUSE
resolver
amino_acid_sequence
MEWMRSRVGTLGLWVRLLLAVFLLGVYQAYPIPDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVRFLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYAS
uniprot
proteins
function
FUNCTION: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. {ECO:0000269|PubMed:15902306, ECO:0000269|PubMed:30605666}.
uniprot
proteins
mass_dalton
23237
uniprot
proteins
protein_family
Heparin-binding growth factors family
uniprot
proteins
pubmed
10858549
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15902306
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
30389664
uniprot
proteins
pubmed
30605666
uniprot
proteins
sequence_length
210
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30605666}.
uniprot
proteins