TAS2R1
entrez
50834
canonical
uniprot
Q9NYW7
canonical
ensembl
ENSG00000169777
resolver
ensp
ENSP00000371932
resolver
enst
ENST00000382492
resolver
genesymbol
TAS2R1
resolver
hgnc
HGNC:14909
resolver
uniprot
Q502V6
resolver
uniprot
Q646G8
resolver
uniprot_entry
Q502V6_HUMAN
resolver
uniprot_entry
TA2R1_HUMAN
resolver
uniprot_sec
Q646G8
resolver
amino_acid_sequence
MLESHLIIYFLLAVIQFLLGIFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYVNVIVIFFIEFIMCSANCAILLFINELELWLATWLGVFYCAKVASVRHPLFIWLKMRISKLVPWMILGSLLYVSMICVFHSKYAGFMVPYFLRKFFSQNATIQKEDTLAIQIFSFVAEFSVPLLIFLFAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAPISALLSILSFLILYFSHCMIKVFLSSLKFHIRRFIFLFFILVIGIYPSGHSLILILGNPKLKQNAKKFLLHSKCCQ
uniprot
proteins
function
FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
uniprot
proteins
mass_dalton
34333
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
10761934
uniprot
proteins
pubmed
10761935
uniprot
proteins
pubmed
11696554
uniprot
proteins
pubmed
12139982
uniprot
proteins
pubmed
12581520
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15496549
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 10..30; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 56..76; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 82..102; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 125..145; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 223..243; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 258..278; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins