Msrb2
entrez
76467
canonical
uniprot
Q78J03
canonical
ensembl
ENSMUSG00000023094
resolver
ensp
ENSMUSP00000023856
resolver
enst
ENSMUST00000023856
resolver
genesymbol
Msrb2
resolver
uniprot_entry
MSRB2_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by high concentrations of substrate. {ECO:0000269|PubMed:14699060}.
uniprot
proteins
amino_acid_sequence
MARLLRALRGLPLLQAPGRLARGCAGSGSKDTGSLTKSKRSLSEADWQKKLTPEQFYVTREKGTEAPFSGMYLNNKETGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAYGSKGSDESHTGILRRLDTSLGCPRMEVVCKQCEAHLGHVFPDGPKPTGQRFCINSVALKFKPSKP
uniprot
proteins
ec_number
1.8.4.12
uniprot
proteins
ec_number
1.8.4.14
uniprot
proteins
function
FUNCTION: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. {ECO:0000269|PubMed:14699060, ECO:0000269|PubMed:23911929}.
uniprot
proteins
mass_dalton
19157
uniprot
proteins
protein_family
MsrB Met sulfoxide reductase family
uniprot
proteins
pubmed
14699060
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
23911929
uniprot
proteins
sequence_length
175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:14699060}.
uniprot
proteins