Slc25a30
entrez
67554
canonical
uniprot
Q9CR58
canonical
ensembl
ENSMUSG00000022003
resolver
ensp
ENSMUSP00000022580
resolver
enst
ENSMUST00000022580
resolver
genesymbol
Slc25a30
resolver
genesymbol_syn
Kmcp1
resolver
uniprot
Q3UAD0
resolver
uniprot_entry
KMCP1_MOUSE
resolver
uniprot_sec
Q3UAD0
resolver
amino_acid_sequence
MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDANFREIRYRGMLHALMRIGREEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLAVERPEDETLLVNVVCGILSGVISSAIANPTDVLKIRMQAQNSAVQGGMIDSFMSIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVATHFLSSFTCGLVGALASNPVDVVRTRMMNQRALRDGRCAGYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFLTYEQLKKLDL
uniprot
proteins
function
FUNCTION: Antiporter that transports inorganic anions (sulfate, sulfite, thiosulfate and phosphate) and, to a lesser extent, a variety of dicarboxylates (e.g. malonate, malate and citramalate) and, even more so, aspartate. The sulfate/sulfate exchange is much higher than the phosphate/phosphate and malate/malate exchanges. The transport affinities is higher for sulfate and thiosulfate than for any other substrate. May catalyze the export of sulfite and thiosulfate (the hydrogen sulfide degradation products) from the mitochondria, thereby modulating the level of the hydrogen sulfide. Also may mediate a very low unidirectional transport of sulfate, phosphate and (S)-malate. {ECO:0000250|UniProtKB:Q5SVS4}.
uniprot
proteins
mass_dalton
32282
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15809292
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
291
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:15809292}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..26; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 71..89; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 106..124; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 164..183; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 204..224; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 264..283; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins