Tbx3
entrez
353305
canonical
uniprot
Q7TST9
canonical
ensembl
ENSRNOG00000008706
resolver
ensembl
ENSRNOG00055014347
resolver
ensembl
ENSRNOG00060002368
resolver
ensembl
ENSRNOG00065005679
resolver
ensp
ENSRNOP00000011552
resolver
ensp
ENSRNOP00000074567
resolver
ensp
ENSRNOP00055020093
resolver
ensp
ENSRNOP00060002594
resolver
ensp
ENSRNOP00065005960
resolver
enst
ENSRNOT00000011552
resolver
enst
ENSRNOT00000084018
resolver
enst
ENSRNOT00055024610
resolver
enst
ENSRNOT00060003734
resolver
enst
ENSRNOT00065008461
resolver
genesymbol
Tbx3
resolver
uniprot
A0A0G2K8D7
resolver
uniprot_entry
A0A0G2K8D7_RAT
resolver
uniprot_entry
TBX3_RAT
resolver
amino_acid_sequence
MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSNLKDLCPSEAESDAEAESKEEHGPEACDTAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADEHRSPGREGPVSAKVDEARALPAKDAFAPLSVQTDATAHLTQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNSMRPRLRYSPYSIPVPVPDSSSLLATALPSMASAAGPLDGKSAVLAASPASVAVDSGSELNSRSSTLSSGSVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRSCSGSP
uniprot
proteins
function
FUNCTION: Transcriptional repressor involved in developmental processes (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes (By similarity). Probably plays a role in limb pattern formation (By similarity). Required for mammary placode induction, involved in maintenance of the mammary buds during development and branching morphogenesis in embryonic and adult glands; partially redundant with TBX2 (By similarity). Involved in modulating early inner ear development, acting independently of, and also redundantly with, TBX2 in different subregions of the developing ear (By similarity). Acts as a negative regulator of PML function in cellular senescence (By similarity). {ECO:0000250|UniProtKB:O15119, ECO:0000250|UniProtKB:P70324}.
uniprot
proteins
mass_dalton
79335
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
743
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
uniprot
proteins