PLGRKT
entrez
55848
canonical
uniprot
Q9HBL7
canonical
ensembl
ENSG00000107020
resolver
ensp
ENSP00000223864
resolver
ensp
ENSP00000575631
resolver
ensp
ENSP00000575632
resolver
ensp
ENSP00000575634
resolver
ensp
ENSP00000575635
resolver
ensp
ENSP00000575637
resolver
ensp
ENSP00000575638
resolver
ensp
ENSP00000618248
resolver
ensp
ENSP00000618249
resolver
enst
ENST00000223864
resolver
enst
ENST00000905572
resolver
enst
ENST00000905573
resolver
enst
ENST00000905575
resolver
enst
ENST00000905576
resolver
enst
ENST00000905578
resolver
enst
ENST00000905579
resolver
enst
ENST00000948189
resolver
enst
ENST00000948190
resolver
genesymbol
PLGRKT
resolver
genesymbol_syn
C9orf46
resolver
hgnc
HGNC:23633
resolver
uniprot
B2R6W0
resolver
uniprot
Q9NZ44
resolver
uniprot_entry
PLRKT_HUMAN
resolver
uniprot_sec
B2R6W0
resolver
uniprot_sec
Q9NZ44
resolver
amino_acid_sequence
MGFIFSKSMNESMKNQKEFMLMNARLQLERQLIMQSEMRERQMAMQIAWSREFLKYFGTFFGLAAISLTAGAIKKKKPAFLVPIVPLSFILTYQYDLGYGTLLERMKGEAEDILETEKSKLQLPRGMITFESIEKARKEQSRFFIDK
uniprot
proteins
function
FUNCTION: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9. {ECO:0000269|PubMed:21940822}.
uniprot
proteins
mass_dalton
17201
uniprot
proteins
pubmed
10931946
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21795689
uniprot
proteins
pubmed
21940822
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
147
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:21940822}; Multi-pass membrane protein {ECO:0000269|PubMed:21940822}. Note=Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins