Taf7
entrez
24074
canonical
uniprot
Q9R1C0
canonical
ensembl
ENSMUSG00000051316
resolver
ensp
ENSMUSP00000065645
resolver
enst
ENSMUST00000066272
resolver
genesymbol
Taf7
resolver
genesymbol_syn
Taf2f
resolver
uniprot_entry
TAF7_MOUSE
resolver
amino_acid_sequence
MSKNKDDAPHELESQFILRLPPEYAATVRRAVQSGHVNLKDKLSIELHPDGRHGIVRVDRVPLAAKLVDLPCVTESLKTIDKKTFYKTADISQMLVATVDGDLYPPVEEAAATADPKANKKKDKDKEKKFVWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKETENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEEDVNILDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK
uniprot
proteins
function
FUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF7 forms a promoter DNA binding subcomplex of TFIID, together with TAF1 and TAF2. Part of a TFIID complex containing TAF10 (TFIID alpha) and a TFIID complex lacking TAF10 (TFIID beta). {ECO:0000250|UniProtKB:Q15545, ECO:0000269|PubMed:10438527}.
uniprot
proteins
mass_dalton
39126
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by CIITA. Phosphorylation at Ser-256 by TAF1 in early G1 phase disrupts binding to TAF1 (By similarity). {ECO:0000250|UniProtKB:Q15545}.; PTM: Ubiquitinated by TRIM26; leading to proteasomal degradation. {ECO:0000250|UniProtKB:Q15545}.
uniprot
proteins
protein_family
TAF7 family
uniprot
proteins
pubmed
10438527
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10438527}.
uniprot
proteins