Decr1
entrez
117543
canonical
uniprot
Q64591
canonical
ensembl
ENSRNOG00000008236
resolver
ensembl
ENSRNOG00055000350
resolver
ensembl
ENSRNOG00060001119
resolver
ensembl
ENSRNOG00065015795
resolver
ensp
ENSRNOP00000011330
resolver
ensp
ENSRNOP00055000482
resolver
ensp
ENSRNOP00060000781
resolver
ensp
ENSRNOP00065020624
resolver
enst
ENSRNOT00000011330
resolver
enst
ENSRNOT00055000620
resolver
enst
ENSRNOT00060001551
resolver
enst
ENSRNOT00065026245
resolver
genesymbol
Decr1
resolver
genesymbol_syn
Decr
resolver
uniprot
G3V734
resolver
uniprot
Q6PCV4
resolver
uniprot_entry
DECR_RAT
resolver
uniprot_entry
G3V734_RAT
resolver
uniprot_sec
Q6PCV4
resolver
amino_acid_sequence
MALLARAFFAGVSRLPCDPGPQRFFSFGTKTLYQSIDAPQSKFFPPILKPMLPPNAFQGKVAFITGGGTGLGKAMTTFLSSLGAQCVIASRNIDVLKATAEEITSKTGNKVYAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLSPNGWKTITDIVLNGTAYVTIEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGKFEKDMIERIPCGRLGTVEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDVIEGLIRKTKGS
uniprot
proteins
ec_number
1.3.1.124
uniprot
proteins
function
FUNCTION: Auxiliary enzyme in the beta-oxidation of mono- and polyunsaturated fatty acids. Together with the Enoyl-CoA delta isomerase 1 (ECI1) and the Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase (ECH1) they allow reentrance of the enoyl-CoA into the beta-oxidation cycle. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Acts primarily on polyunsaturated fatty acids. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Based on its established catalytic mechanism, it is predicted to act also on other fatty acids besides those tested experimentally. {ECO:0000250|UniProtKB:Q16698}.
uniprot
proteins
mass_dalton
36133
uniprot
proteins
protein_family
2
uniprot
proteins
protein_family
4-dienoyl-CoA reductase subfamily
uniprot
proteins
protein_family
Short-chain dehydrogenases/reductases (SDR) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2383590
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305|PubMed:2383590}.
uniprot
proteins