Dpy30
entrez
286897
canonical
uniprot
Q8K3E7
canonical
ensembl
ENSRNOG00000027126
resolver
ensp
ENSRNOP00000110515
resolver
enst
ENSRNOT00000156805
resolver
genesymbol
Dpy30
resolver
genesymbol_syn
Aip1
resolver
uniprot
A0ABK0LYC3
resolver
uniprot_entry
A0ABK0LYC3_RAT
resolver
uniprot_entry
DPY30_RAT
resolver
amino_acid_sequence
MESEQMLEGQTQVAENPHSEYGLTDSVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPTEFLASYLLKNKAQFEDRN
uniprot
proteins
function
FUNCTION: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem cells, may play a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11201
uniprot
proteins
protein_family
Dpy-30 family
uniprot
proteins
pubmed
19651892
uniprot
proteins
sequence_length
99
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Golgi apparatus, trans-Golgi network {ECO:0000250}.
uniprot
proteins