Mmadhc
entrez
362134
canonical
uniprot
Q6AYQ6
canonical
ensembl
ENSRNOG00000004740
resolver
ensp
ENSRNOP00000100141
resolver
genesymbol
Mmadhc
resolver
uniprot_entry
MMAD_RAT
resolver
amino_acid_sequence
MAHVLCNRARLVSYLPGFCSLVKRVINPRAFSTAGSSGSDESHVATAPPDICSRTVWPDETMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSQAHKTLPDVLAEPLSTERHEFVMAQYVNEFQDSNAPVEQEISSAETYFESARVECAIQTCPELLRRDFESLFPEVANSKLMILTVTQKTEHDMTVWSEEVEVEREALLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIRHGLWGTHVVVGSIFTNATADSHIMRKLSGD
uniprot
proteins
function
FUNCTION: Involved in cobalamin metabolism and trafficking. Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl). Promotes oxidation of cob(II)alamin bound to MMACHC. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine. {ECO:0000250|UniProtKB:Q9H3L0}.
uniprot
proteins
mass_dalton
33052
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
296
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H3L0}. Mitochondrion {ECO:0000250|UniProtKB:Q9H3L0}.
uniprot
proteins