RPRM
entrez
56475
canonical
uniprot
Q9NS64
canonical
ensembl
ENSG00000177519
resolver
ensp
ENSP00000314946
resolver
enst
ENST00000325926
resolver
genesymbol
RPRM
resolver
hgnc
HGNC:24201
resolver
uniprot
B2R4V1
resolver
uniprot_entry
RPRM_HUMAN
resolver
uniprot_sec
B2R4V1
resolver
amino_acid_sequence
MNPALGNQTDVAGLFLANSSEALERAVRCCTQASVVTDDGFAEGGPDERSLYIMRVVQIAVMCVLSLTVVFGIFFLGCNLLIKSEGMINFLVKDRRPSKEVEAVVVGPY
uniprot
proteins
function
FUNCTION: May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11774
uniprot
proteins
protein_family
Reprimo family
uniprot
proteins
pubmed
10930422
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16303743
uniprot
proteins
sequence_length
109
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins