Fez1
entrez
235180
canonical
uniprot
Q8K0X8
canonical
ensembl
ENSMUSG00000032118
resolver
ensp
ENSMUSP00000034630
resolver
ensp
ENSMUSP00000126072
resolver
ensp
ENSMUSP00000260808
resolver
ensp
ENSMUSP00000260810
resolver
ensp
ENSMUSP00000260811
resolver
ensp
ENSMUSP00000260830
resolver
ensp
ENSMUSP00000260842
resolver
ensp
ENSMUSP00000356258
resolver
enst
ENSMUST00000034630
resolver
enst
ENSMUST00000163816
resolver
genesymbol
Fez1
resolver
uniprot
Q3YE74
resolver
uniprot_entry
FEZ1_MOUSE
resolver
uniprot_sec
Q3YE74
resolver
amino_acid_sequence
MEAPLVSLDEEFEDIRPSCTEEPEEKPQCLYGTSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTESLAPVKNQLQIQEEEETLRDEEVWDALTDNYIPSLSEDWRDPNIEALNGNSSDIEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGEISSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDRVEGAIRDFSEELVHQLARRDELEFEKEVKNSFITVLIEVQNKQREQRELMKKRRKEKGLSLQSNRIEKGSQMPLKRFSMEGISNILQSGIRQTFGSSGADRQYLNTVIPYEKKSSPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYILKVLCPT
uniprot
proteins
function
FUNCTION: May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. May participate in the transport of mitochondria and other cargos along microtubules (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
45215
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by protein kinase C zeta; which enhances interaction with UBE4B and polyubiquitination. {ECO:0000250}.; PTM: Polyubiquitinated in a UBE4B-dependent manner; which does not lead to proteasomal degradation and may be important for neurogenic activity. Polyubiquitin linkage seems to be mainly through Lys-26 (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Zygin family
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
392
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). {ECO:0000250}.
uniprot
proteins