CLGN
entrez
1047
canonical
uniprot
O14967
canonical
ensembl
ENSG00000153132
resolver
ensp
ENSP00000326699
resolver
ensp
ENSP00000392782
resolver
genesymbol
CLGN
resolver
hgnc
HGNC:2060
resolver
uniprot
A0A140VKG2
resolver
uniprot
B3KS90
resolver
uniprot
B4DXV8
resolver
uniprot
D3DNY8
resolver
uniprot_entry
A0A140VKG2_HUMAN
resolver
uniprot_entry
CLGN_HUMAN
resolver
uniprot_sec
B3KS90
resolver
uniprot_sec
B4DXV8
resolver
uniprot_sec
D3DNY8
resolver
amino_acid_sequence
MHFQAFWLCLGLLFISINAEFMDDDVETEDFEENSEEIDVNESELSSEIKYKTPQPIGEVYFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFGPDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRIGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEEKKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEMKEADESTGSGDGPIKSVRKRRVRKD
uniprot
proteins
function
FUNCTION: Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
70039
uniprot
proteins
protein_family
Calreticulin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17507649
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
9434179
uniprot
proteins
sequence_length
610
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 472..492; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins