Tmed4
entrez
103694
canonical
uniprot
Q8R1V4
canonical
ensembl
ENSMUSG00000004394
resolver
ensp
ENSMUSP00000004508
resolver
enst
ENSMUST00000004508
resolver
genesymbol
Tmed4
resolver
genesymbol_syn
Ers25
resolver
uniprot
Q3TY55
resolver
uniprot_entry
TMED4_MOUSE
resolver
uniprot_sec
Q3TY55
resolver
amino_acid_sequence
MAGVGVGPLQGMVRFGLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
uniprot
proteins
function
FUNCTION: Involved in vesicular protein trafficking, mainly in the early secretory pathway. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity). {ECO:0000250, ECO:0000269|PubMed:18326488}.
uniprot
proteins
mass_dalton
26022
uniprot
proteins
protein_family
EMP24/GP25L family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18326488
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18326488}; Single-pass type I membrane protein {ECO:0000269|PubMed:18326488}.
uniprot
proteins
transmembrane_region
TRANSMEM 195..212; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins