BANP
entrez
54971
canonical
uniprot
Q8N9N5
canonical
ensembl
ENSG00000172530
resolver
ensp
ENSP00000347125
resolver
ensp
ENSP00000376902
resolver
ensp
ENSP00000376903
resolver
ensp
ENSP00000432508
resolver
ensp
ENSP00000444352
resolver
ensp
ENSP00000487304
resolver
ensp
ENSP00000507916
resolver
ensp
ENSP00000515015
resolver
ensp
ENSP00000524771
resolver
ensp
ENSP00000524772
resolver
ensp
ENSP00000524774
resolver
ensp
ENSP00000524775
resolver
ensp
ENSP00000524776
resolver
ensp
ENSP00000524779
resolver
ensp
ENSP00000524782
resolver
ensp
ENSP00000524788
resolver
ensp
ENSP00000524791
resolver
ensp
ENSP00000524793
resolver
ensp
ENSP00000524794
resolver
ensp
ENSP00000524796
resolver
ensp
ENSP00000524798
resolver
ensp
ENSP00000524807
resolver
ensp
ENSP00000524808
resolver
ensp
ENSP00000589400
resolver
ensp
ENSP00000589402
resolver
ensp
ENSP00000639766
resolver
ensp
ENSP00000639768
resolver
ensp
ENSP00000639769
resolver
ensp
ENSP00000639779
resolver
ensp
ENSP00000639783
resolver
enst
ENST00000682872
resolver
enst
ENST00000700483
resolver
enst
ENST00000854715
resolver
enst
ENST00000854716
resolver
enst
ENST00000854720
resolver
enst
ENST00000854729
resolver
enst
ENST00000854748
resolver
enst
ENST00000854749
resolver
enst
ENST00000919341
resolver
enst
ENST00000919343
resolver
enst
ENST00000969707
resolver
enst
ENST00000969709
resolver
enst
ENST00000969710
resolver
enst
ENST00000969724
resolver
genesymbol
BANP
resolver
genesymbol_syn
BEND1
resolver
genesymbol_syn
SMAR1
resolver
hgnc
HGNC:13450
resolver
uniprot
A0A0S2Z5C2
resolver
uniprot
A0A0S2Z5M2
resolver
uniprot
A0A804HKG3
resolver
uniprot
A0ACI8RFZ3
resolver
uniprot
A8MU25
resolver
uniprot
A8MX25
resolver
uniprot
B2RCF7
resolver
uniprot
B3KM38
resolver
uniprot
B4DE54
resolver
uniprot
B4DNJ9
resolver
uniprot
F5GZM0
resolver
uniprot
Q96GJ7
resolver
uniprot
Q9NWY1
resolver
uniprot_entry
A0A0S2Z5C2_HUMAN
resolver
uniprot_entry
A0A0S2Z5M2_HUMAN
resolver
uniprot_entry
A0A804HKG3_HUMAN
resolver
uniprot_entry
A0ACI8RFZ3_HUMAN
resolver
uniprot_entry
B3KM38_HUMAN
resolver
uniprot_entry
B4DE54_HUMAN
resolver
uniprot_entry
BANP_HUMAN
resolver
uniprot_sec
A8MU25
resolver
uniprot_sec
A8MX25
resolver
uniprot_sec
B2RCF7
resolver
uniprot_sec
B4DNJ9
resolver
uniprot_sec
F5GZM0
resolver
uniprot_sec
Q96GJ7
resolver
uniprot_sec
Q9NWY1
resolver
amino_acid_sequence
MMSEHDLADVVQIAVEDLSPDHPVVLENHVVTDEDEPALKRQRLEINCQDPSIKTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENVISNAVPGRRQNTIVVKVPGQEDSHHEDGESGSEASDSVSSCGQAGSQSIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPNSSSYCPSEPMMSTPPPASELPQPQPQPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQLLEATRIPCLLAPSVFKASSGQVLQGAQLIAVASSDPAAAGVDGSPLQGSDIQVQYVQLAPVSDHTAGAQTAEALQPTLQPEMQLEHGAIQIQ
uniprot
proteins
function
FUNCTION: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397). {ECO:0000250|UniProtKB:Q8VBU8, ECO:0000269|PubMed:16166625, ECO:0000269|PubMed:26080397}.
uniprot
proteins
mass_dalton
56494
uniprot
proteins
post_translational_modification
PTM: MAPK1/MAPK3-mediated phosphorylation at Thr-337 and Thr-352 results in export to the cytoplasm. {ECO:0000250|UniProtKB:Q8VBU8}.
uniprot
proteins
protein_family
BANP/SMAR1 family
uniprot
proteins
pubmed
10940556
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
16166625
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
26080397
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
519
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16166625, ECO:0000269|PubMed:26080397}. Nucleus speckle {ECO:0000269|PubMed:26080397}. Cytoplasm {ECO:0000269|PubMed:26080397}. Note=Primarily nuclear but translocates to the cytoplasm following MAPK1/MAPK3-mediated phosphorylation. {ECO:0000269|PubMed:26080397}.
uniprot
proteins