Atp1a2
entrez
98660
canonical
uniprot
Q6PIE5
canonical
ensembl
ENSMUSG00000007097
resolver
ensp
ENSMUSP00000083077
resolver
enst
ENSMUST00000085913
resolver
genesymbol
Atp1a2
resolver
uniprot
Q3UHK5
resolver
uniprot
Q80UZ8
resolver
uniprot_entry
AT1A2_MOUSE
resolver
uniprot_entry
Q3UHK5_MOUSE
resolver
uniprot_sec
Q80UZ8
resolver
amino_acid_sequence
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGALLCFLAYGILAAMEDEPSNDNLYLGIVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGQTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILRDHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTTNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
uniprot
proteins
ec_number
7.2.2.13
uniprot
proteins
function
FUNCTION: Catalytic subunit of the Na(+)/K(+)-ATPase that hydrolyzes ATP to exchange ions across the plasma membrane, exporting 3 Na(+) and importing 2 K(+) per cycle (By similarity). It undergoes ATP-driven conformational changes that allow alternating binding and release of Na(+) and K(+) ions across the membrane (By similarity). This process maintains essential Na(+) and K(+) gradients for membrane potential and cellular function (By similarity). {ECO:0000250|UniProtKB:P05023, ECO:0000250|UniProtKB:P50993}.
uniprot
proteins
mass_dalton
112217
uniprot
proteins
protein_family
Cation transport ATPase (P-type) (TC 3.A.3) family
uniprot
proteins
protein_family
Type IIC subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15564586
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1020
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:P50993}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P50993}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 130..150; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 287..306; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 319..336; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 770..789; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 800..820; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 841..863; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 916..935; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 949..967; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 983..1003; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins