PCSK6
entrez
5046
canonical
uniprot
P29122
canonical
ensembl
ENSG00000140479
resolver
ensp
ENSP00000332052
resolver
ensp
ENSP00000381246
resolver
ensp
ENSP00000477768
resolver
ensp
ENSP00000478081
resolver
ensp
ENSP00000479496
resolver
ensp
ENSP00000482760
resolver
enst
ENST00000331826
resolver
genesymbol
PCSK6
resolver
genesymbol_syn
PACE4
resolver
hgnc
HGNC:8569
resolver
uniprot
A2RQD9
resolver
uniprot
H7BXT3
resolver
uniprot
Q15099
resolver
uniprot
Q15100
resolver
uniprot
Q59H04
resolver
uniprot
Q9UEG7
resolver
uniprot
Q9UEJ1
resolver
uniprot
Q9UEJ2
resolver
uniprot
Q9UEJ7
resolver
uniprot
Q9UEJ8
resolver
uniprot
Q9UEJ9
resolver
uniprot
Q9Y4G9
resolver
uniprot
Q9Y4H0
resolver
uniprot
Q9Y4H1
resolver
uniprot_entry
A2RQD9_HUMAN
resolver
uniprot_entry
H7BXT3_HUMAN
resolver
uniprot_entry
PCSK6_HUMAN
resolver
uniprot_entry
Q59H04_HUMAN
resolver
uniprot_sec
Q15099
resolver
uniprot_sec
Q15100
resolver
uniprot_sec
Q9UEG7
resolver
uniprot_sec
Q9UEJ1
resolver
uniprot_sec
Q9UEJ2
resolver
uniprot_sec
Q9UEJ7
resolver
uniprot_sec
Q9UEJ8
resolver
uniprot_sec
Q9UEJ9
resolver
uniprot_sec
Q9Y4G9
resolver
uniprot_sec
Q9Y4H0
resolver
uniprot_sec
Q9Y4H1
resolver
amino_acid_sequence
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAACSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYHTFSAHQSRSRMLELSAPELEPPKAALSPSQVEVPEDEEDYTAQSTPGSANILQTSVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTGFTQLGTSCITNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTCLLAG
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues.
uniprot
proteins
mass_dalton
106420
uniprot
proteins
protein_family
Peptidase S8 family
uniprot
proteins
pubmed
10215603
uniprot
proteins
pubmed
16433634
uniprot
proteins
pubmed
1741956
uniprot
proteins
pubmed
7980617
uniprot
proteins
pubmed
8179631
uniprot
proteins
pubmed
8906861
uniprot
proteins
pubmed
9192737
uniprot
proteins
pubmed
9378725
uniprot
proteins
pubmed
9738469
uniprot
proteins
sequence_length
969
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform PACE4A-I]: Secreted.; SUBCELLULAR LOCATION: [Isoform PACE4A-II]: Secreted.; SUBCELLULAR LOCATION: [Isoform PACE4C]: Endoplasmic reticulum. Note=Not secreted, remains probably in zymogen form in endoplasmic reticulum.; SUBCELLULAR LOCATION: [Isoform PACE4CS]: Endoplasmic reticulum. Note=Not secreted, remains probably in zymogen form in endoplasmic reticulum.; SUBCELLULAR LOCATION: [Isoform PACE4E-I]: Endomembrane system; Peripheral membrane protein. Note=Retained intracellularly probably through a hydrophobic cluster in their C-terminus.; SUBCELLULAR LOCATION: [Isoform PACE4E-II]: Endomembrane system; Peripheral membrane protein. Note=Retained intracellularly probably through a hydrophobic cluster in their C-terminus.; SUBCELLULAR LOCATION: [Isoform PACE4B]: Secreted.
uniprot
proteins