A0A455ZAR2
uniprot
A0A455ZAR2
canonical
amino_acid_sequence
MLWLPDRGSCSARSPSGMLRGAPGGWRYGRRCGRRRQSCCCCCCCSHVGAPLSFHREASLVSHDGHDIMKQHCGEESIRGAHGYKNK
uniprot
proteins
function
FUNCTION: Enhances the binding of the PAF1 complex to target gene promoters and plays a role in negative regulation of transcription (PubMed:30367041). May function as an anchor to keep the PAF1 complex on target gene promoters, sequentially pausing RNA polymerase II-induced mRNA elongation (PubMed:30367041). Inhibits FOXM1-mediated transcription of PHB2 (PubMed:33754036). {ECO:0000269|PubMed:30367041, ECO:0000269|PubMed:33754036}.
uniprot
proteins
mass_dalton
9607
uniprot
proteins
pubmed
30367041
uniprot
proteins
pubmed
33754036
uniprot
proteins
sequence_length
87
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:30367041}.
uniprot
proteins