Frs3
entrez
107971
canonical
uniprot
Q91WJ0
canonical
ensembl
ENSMUSG00000023266
resolver
ensp
ENSMUSP00000108921
resolver
ensp
ENSMUSP00000235228
resolver
ensp
ENSMUSP00000235231
resolver
enst
ENSMUST00000113296
resolver
genesymbol
Frs3
resolver
genesymbol_syn
Frs2b
resolver
uniprot_entry
FRS3_MOUSE
resolver
amino_acid_sequence
MGSCWSCLDRDSVPHNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHQREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEDIFNLLQDLMQCNSINVTEEPVIITRSSHPPELDLPRGPPQPAGYTVSGFSNGFPGCPGEGPRFSSAPRRPSTSSLRHPSPGEESTHTLIASEEQSHTYVNTPTGDEDGRSRHCLQPLPEGRVPLPAQTQGSDQRDPQVLLQPGQVKFVLGPTPARRQVMKCQSLCPGMQDPPHHNNNEGPSECPAQPKCTYENVSGGLQQGAGWRLSPEERGWSGLAHRRAALLHYENLPPLPPVWESQGQQPGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRASARSHSGFPVPLTRRRGSPRVFNFDFRRQGPEPPRQLNYIQVELKGWGTARPKGPQNPSVSGAPGPTPHPVRSSDSYAVIDLKKTAAMSDLQRALPRDDGAVRKTRHNSTDLPL
uniprot
proteins
function
FUNCTION: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
uniprot
proteins
mass_dalton
53976
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB. Phosphorylated by ULK2 in vitro. {ECO:0000269|PubMed:16887332}.
uniprot
proteins
pubmed
10629055
uniprot
proteins
pubmed
12688531
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16887332
uniprot
proteins
sequence_length
492
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Lipid-anchor.
uniprot
proteins