Mocs1
entrez
56738
canonical
uniprot
Q5RKZ7
canonical
ensembl
ENSMUSG00000064120
resolver
ensp
ENSMUSP00000024797
resolver
ensp
ENSMUSP00000133694
resolver
genesymbol
Mocs1
resolver
uniprot
B2RVW8
resolver
uniprot
B7ZWI5
resolver
uniprot
Q8R058
resolver
uniprot
Q9JL32
resolver
uniprot
Q9JL33
resolver
uniprot_entry
MOCS1_MOUSE
resolver
uniprot_sec
B2RVW8
resolver
uniprot_sec
B7ZWI5
resolver
uniprot_sec
Q8R058
resolver
uniprot_sec
Q9JL32
resolver
uniprot_sec
Q9JL33
resolver
amino_acid_sequence
MAARPAFGIVRQLLRSNARGCSSGAPVTQPRPGEPSRPTREGLSLRLQFLQEHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVARLHGLEGLRTIGLTTNGINLARLLPRLQQAGLNAVNISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYKPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTIRQRWPGLEKLPEEDSSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLRAGASEEELLRIIGAAVGRKKRQHAGMFNIAQMKNRPMILIGVLLMLQDSPPARWSNFSWDPLRVRNPSARQCLSDQMASLWKRHCIPKALPLSQQCLGSGSPQRHYSSYPDPDTHSKCLSTGSQAPDAPSGPGPTSNQLTHVDSAGRASMVDVGGKPETERVAVASAMVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIPLCHHVALSHVQVHLELDSTRHAVLIQASCRARGPTGVEMEALTSAAMAALTVYDMCKAVSRDIVVTEVKLISKTGGQRGDFHRA
uniprot
proteins
ec_number
4.1.99.22
uniprot
proteins
ec_number
4.6.1.17
uniprot
proteins
function
FUNCTION: Isoform Mocs1a and isoform Mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). Mocs1a catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and Mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP. {ECO:0000250|UniProtKB:Q9NZB8}.
uniprot
proteins
mass_dalton
69859
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
uniprot
proteins
protein_family
MoaA family
uniprot
proteins
protein_family
MoaC family; Radical SAM superfamily
uniprot
proteins
pubmed
10917590
uniprot
proteins
pubmed
12471057
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15862276
uniprot
proteins
pubmed
17236133
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
sequence_length
636
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9NZB8}.; SUBCELLULAR LOCATION: [Isoform Mocs1a]: Mitochondrion matrix {ECO:0000250|UniProtKB:Q9NZB8}.; SUBCELLULAR LOCATION: [Isoform Mocs1b]: Mitochondrion matrix {ECO:0000250|UniProtKB:Q9NZB8}.
uniprot
proteins