Dnajb9
entrez
24908
canonical
uniprot
P97554
canonical
ensembl
ENSRNOG00000004006
resolver
ensembl
ENSRNOG00055019714
resolver
ensembl
ENSRNOG00060004629
resolver
ensembl
ENSRNOG00065009492
resolver
ensp
ENSRNOP00000005363
resolver
ensp
ENSRNOP00000099445
resolver
ensp
ENSRNOP00055027291
resolver
ensp
ENSRNOP00060005785
resolver
ensp
ENSRNOP00065011387
resolver
enst
ENSRNOT00000005363
resolver
enst
ENSRNOT00000160259
resolver
enst
ENSRNOT00055033641
resolver
enst
ENSRNOT00060007720
resolver
enst
ENSRNOT00065015185
resolver
genesymbol
Dnajb9
resolver
genesymbol_syn
Mdg1
resolver
uniprot
A0ABK0KXJ0
resolver
uniprot_entry
A0ABK0KXJ0_RAT
resolver
uniprot_entry
DNJB9_RAT
resolver
amino_acid_sequence
MATPQSVFVFAICILMITELILASKNYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDANRRKEYDIIGHSAFTNGKGQRSNGSPFEQSFNFNFDDLFKDFNLFGQNQNTRSKKHFENHFQTRQDGSSRQRHHFQEFSFGGGLFDDMFEDMEKMFSFSGFDSTNRRTVQTENRFHGSSKHCRTVTQRRGNMVTTYTDCSGQ
uniprot
proteins
function
FUNCTION: Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (By similarity). In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similarity). Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production (By similarity). {ECO:0000250|UniProtKB:G3H0N9, ECO:0000250|UniProtKB:Q9QYI6}.
uniprot
proteins
mass_dalton
25717
uniprot
proteins
pubmed
11525638
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
222
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000250|UniProtKB:Q9QYI6}.
uniprot
proteins