SRSF9
entrez
8683
canonical
uniprot
Q13242
canonical
ensembl
ENSG00000111786
resolver
ensp
ENSP00000229390
resolver
ensp
ENSP00000627825
resolver
ensp
ENSP00000627826
resolver
ensp
ENSP00000627827
resolver
enst
ENST00000229390
resolver
enst
ENST00000957766
resolver
enst
ENST00000957767
resolver
enst
ENST00000957768
resolver
genesymbol
SRSF9
resolver
genesymbol_syn
SFRS9
resolver
genesymbol_syn
SRP30C
resolver
hgnc
HGNC:10791
resolver
uniprot
Q52LD1
resolver
uniprot_entry
SRSF9_HUMAN
resolver
uniprot_sec
Q52LD1
resolver
amino_acid_sequence
MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY
uniprot
proteins
function
FUNCTION: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:10196175, ECO:0000269|PubMed:11875052, ECO:0000269|PubMed:12024014, ECO:0000269|PubMed:12604611, ECO:0000269|PubMed:15009090, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:15695522, ECO:0000269|PubMed:7556075}.
uniprot
proteins
mass_dalton
25542
uniprot
proteins
post_translational_modification
PTM: Extensively phosphorylated on serine residues in the RS domain. {ECO:0000250}.
uniprot
proteins
protein_family
Splicing factor SR family
uniprot
proteins
pubmed
10022843
uniprot
proteins
pubmed
10196175
uniprot
proteins
pubmed
11694584
uniprot
proteins
pubmed
11875052
uniprot
proteins
pubmed
12024014
uniprot
proteins
pubmed
12604611
uniprot
proteins
pubmed
15009090
uniprot
proteins
pubmed
15009664
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15695522
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19367720
uniprot
proteins
pubmed
19523114
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
7556075
uniprot
proteins
pubmed
9671816
uniprot
proteins
pubmed
9685386
uniprot
proteins
sequence_length
221
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10196175, ECO:0000269|PubMed:11694584, ECO:0000269|PubMed:12024014, ECO:0000269|PubMed:12604611}. Note=Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies. Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells.
uniprot
proteins