STEAP2
entrez
261729
canonical
uniprot
Q8NFT2
canonical
ensembl
ENSG00000157214
resolver
ensp
ENSP00000287908
resolver
ensp
ENSP00000378119
resolver
ensp
ENSP00000378120
resolver
ensp
ENSP00000378123
resolver
ensp
ENSP00000378125
resolver
ensp
ENSP00000378128
resolver
ensp
ENSP00000550678
resolver
ensp
ENSP00000550679
resolver
ensp
ENSP00000550680
resolver
ensp
ENSP00000636572
resolver
ensp
ENSP00000636573
resolver
ensp
ENSP00000786539
resolver
genesymbol
STEAP2
resolver
genesymbol_syn
PCANAP1
resolver
genesymbol_syn
STAMP1
resolver
hgnc
HGNC:17885
resolver
uniprot
A4D1F1
resolver
uniprot
B3KS24
resolver
uniprot
G5E9C6
resolver
uniprot
Q6UXN6
resolver
uniprot
Q6YPB1
resolver
uniprot
Q6YPB2
resolver
uniprot
Q8IUE7
resolver
uniprot_entry
B3KS24_HUMAN
resolver
uniprot_entry
Q6YPB2_HUMAN
resolver
uniprot_entry
STEA2_HUMAN
resolver
uniprot_sec
A4D1F1
resolver
uniprot_sec
G5E9C6
resolver
uniprot_sec
Q6UXN6
resolver
uniprot_sec
Q6YPB1
resolver
uniprot_sec
Q8IUE7
resolver
amino_acid_sequence
MESISMMGSPKSLSETFLPNGINGIKDARKVTVGVIGSGDFAKSLTIRLIRCGYHVVIGSRNPKFASEFFPHVVDVTHHEDALTKTNIIFVAIHREHYTSLWDLRHLLVGKILIDVSNNMRINQYPESNAEYLASLFPDSLIVKGFNVVSAWALQLGPKDASRQVYICSNNIQARQQVIELARQLNFIPIDLGSLSSAREIENLPLRLFTLWRGPVVVAISLATFFFLYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAGLLAAAYQLYYGTKYRRFPPWLETWLQCRKQLGLLSFFFAMVHVAYSLCLPMRRSERYLFLNMAYQQVHANIENSWNEEEVWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALNWREFSFIQSTLGYVALLISTFHVLIYGWKRAFEEEYYRFYTPPNFVLALVLPSIVILGKIILFLPCISRKLKRIKKGWEKSQFLEEGMGGTIPHVSPERVTVM
uniprot
proteins
ec_number
1.16.1.-
uniprot
proteins
function
FUNCTION: Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane (By similarity). Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity). Can also reduce Cu(2+) to Cu(1+) (By similarity). {ECO:0000250|UniProtKB:Q687X5, ECO:0000250|UniProtKB:Q8BWB6}.
uniprot
proteins
mass_dalton
56056
uniprot
proteins
protein_family
STEAP family
uniprot
proteins
pubmed
12095985
uniprot
proteins
pubmed
12429817
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
16609065
uniprot
proteins
pubmed
18669648
uniprot
proteins
sequence_length
490
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane {ECO:0000250|UniProtKB:Q8BWB6}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:12429817}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 208..228; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 259..279; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 305..325; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 359..379; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 393..413; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 432..452; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins