Lrrfip1
entrez
367314
canonical
uniprot
Q66HF9
canonical
ensembl
ENSRNOG00000019892
resolver
ensp
ENSRNOP00000045021
resolver
ensp
ENSRNOP00000076434
resolver
ensp
ENSRNOP00000076897
resolver
ensp
ENSRNOP00000080509
resolver
ensp
ENSRNOP00000088829
resolver
ensp
ENSRNOP00000095213
resolver
ensp
ENSRNOP00000112353
resolver
enst
ENSRNOT00000095067
resolver
enst
ENSRNOT00000100660
resolver
enst
ENSRNOT00000100990
resolver
enst
ENSRNOT00000112051
resolver
enst
ENSRNOT00000153243
resolver
genesymbol
Lrrfip1
resolver
uniprot
A0A8I5Y0X7
resolver
uniprot
A0A8I5Y5U1
resolver
uniprot
A0A8I5ZPV3
resolver
uniprot
A0A8I6A6Y5
resolver
uniprot
A0ABK0M8G1
resolver
uniprot_entry
A0A8I5Y0X7_RAT
resolver
uniprot_entry
A0A8I5Y5U1_RAT
resolver
uniprot_entry
A0A8I5ZPV3_RAT
resolver
uniprot_entry
A0A8I6A6Y5_RAT
resolver
uniprot_entry
A0ABK0M8G1_RAT
resolver
uniprot_entry
LRRF1_RAT
resolver
amino_acid_sequence
MTSPEGAQNKEIDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKEVEERPDKDFAEKGSRNMPSLSAATLASLGGTSSRRGSGDTSISMDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESQRQYEEKNKEFEREKHAHSILQFQFAEVKEALRQREEMLEKHGIILNSEIATNGETSDTVNDVGYQAPTKITKEELNALKAAGEGTLGKAKEVEVKKEIVEKVGQRETLQDSEQEQPKLNTGKDCVDRGVLHPGEKAENQRPVEDSALSPGPLAGAKCEQEVQSQDQENTSILKSPEQIESHEVTNKSDSRDSNSPEPSSCRGGLDSEVSGPTALGIKNQSENSMDSQGKENQEDLGKGSFEPRPDHVLGQTPEIDKVSCTDSRGTGGNHLEDVVQAGDTIVEDQVGTMASAEQSKSMENHIGRSLNDGLGQSSERELAHEAAELEEALTQSSQAGGENTVTEAEDAAVRDEKPLQADVQATPAAPTVQSGHQDTTGPGSTDTKHTSPHAKERNKAKSEQQAEALDSPQKKTKNKKKKNKKKKAAAPMETCKDANEESSCQDPDVGDGEEEERVQATDKKWAAETPELKEDPQSRPSGKQNDAEEDSGPAEGPTDVLDQNSLQCADGDISPVGRKGPQRDASQIGGEEGLVPSQHPGQADEKGIEGHSVDNSDLSGELGGFNSESGEQAREEVGNSKSKEDCTMS
uniprot
proteins
function
FUNCTION: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity). {ECO:0000250, ECO:0000269|PubMed:10364563}.
uniprot
proteins
mass_dalton
80019
uniprot
proteins
protein_family
LRRFIP family
uniprot
proteins
pubmed
10364563
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
738
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}.
uniprot
proteins