Sec11a
entrez
56529
canonical
uniprot
Q9R0P6
canonical
ensembl
ENSMUSG00000025724
resolver
ensp
ENSMUSP00000026818
resolver
ensp
ENSMUSP00000113601
resolver
ensp
ENSMUSP00000244377
resolver
ensp
ENSMUSP00000244382
resolver
ensp
ENSMUSP00000244383
resolver
enst
ENSMUST00000026818
resolver
enst
ENSMUST00000117383
resolver
genesymbol
Sec11a
resolver
genesymbol_syn
Sec11l1
resolver
genesymbol_syn
Sid2895
resolver
genesymbol_syn
Spc18
resolver
uniprot
D3Z569
resolver
uniprot_entry
D3Z569_MOUSE
resolver
uniprot_entry
SC11A_MOUSE
resolver
amino_acid_sequence
MLSLDFLDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE
uniprot
proteins
ec_number
3.4.21.89
uniprot
proteins
function
FUNCTION: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids. {ECO:0000250|UniProtKB:P67812}.
uniprot
proteins
mass_dalton
20626
uniprot
proteins
protein_family
Peptidase S26B family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
179
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P67811}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P67811}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..36; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins