SFXN3
entrez
81855
canonical
uniprot
Q9BWM7
canonical
ensembl
ENSG00000107819
resolver
ensp
ENSP00000377103
resolver
ensp
ENSP00000513933
resolver
ensp
ENSP00000566297
resolver
ensp
ENSP00000566298
resolver
ensp
ENSP00000566299
resolver
ensp
ENSP00000566300
resolver
ensp
ENSP00000566301
resolver
ensp
ENSP00000566302
resolver
ensp
ENSP00000566303
resolver
ensp
ENSP00000624911
resolver
ensp
ENSP00000624912
resolver
enst
ENST00000393459
resolver
enst
ENST00000896239
resolver
enst
ENST00000896240
resolver
enst
ENST00000896241
resolver
enst
ENST00000896242
resolver
enst
ENST00000896243
resolver
enst
ENST00000954852
resolver
enst
ENST00000954853
resolver
genesymbol
SFXN3
resolver
hgnc
HGNC:16087
resolver
uniprot
B4DRS6
resolver
uniprot
Q8NCJ0
resolver
uniprot
Q9NTP4
resolver
uniprot_entry
B4DRS6_HUMAN
resolver
uniprot_entry
SFXN3_HUMAN
resolver
uniprot_sec
Q8NCJ0
resolver
uniprot_sec
Q9NTP4
resolver
amino_acid_sequence
MGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAGVVTPGITEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDTPITVRQLGTAYVSATTGAVATALGLKSLTKHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVADEAGQRLGYSVTAAKQGIFQVVISRICMAIPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQKSSIHISNLEPELRAQIHEQNPSVEVVYYNKGL
uniprot
proteins
function
FUNCTION: Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778). {ECO:0000269|PubMed:30442778}.
uniprot
proteins
mass_dalton
35503
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
25732826
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
30442778
uniprot
proteins
sequence_length
321
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000269|PubMed:30442778, ECO:0000269|Ref.4}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 146..164; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins