Ppp2r2a
entrez
117104
canonical
uniprot
P36876
canonical
ensembl
ENSRNOG00000011158
resolver
ensembl
ENSRNOG00055006816
resolver
ensembl
ENSRNOG00060011896
resolver
ensembl
ENSRNOG00065018068
resolver
ensp
ENSRNOP00000015318
resolver
ensp
ENSRNOP00055008862
resolver
ensp
ENSRNOP00060015970
resolver
ensp
ENSRNOP00065024361
resolver
enst
ENSRNOT00000015318
resolver
enst
ENSRNOT00055011291
resolver
enst
ENSRNOT00060020309
resolver
enst
ENSRNOT00065030623
resolver
genesymbol
Ppp2r2a
resolver
uniprot
A1A5M9
resolver
uniprot
O35512
resolver
uniprot
P36878
resolver
uniprot_entry
2ABA_RAT
resolver
uniprot_sec
A1A5M9
resolver
uniprot_sec
O35512
resolver
uniprot_sec
P36878
resolver
amino_acid_sequence
MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN
uniprot
proteins
function
FUNCTION: Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67 (By similarity). Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint (By similarity). {ECO:0000250|UniProtKB:P63151, ECO:0000250|UniProtKB:Q6P1F6}.
uniprot
proteins
mass_dalton
51678
uniprot
proteins
protein_family
Phosphatase 2A regulatory subunit B family
uniprot
proteins
pubmed
1370560
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8389301
uniprot
proteins
sequence_length
447
uniprot
proteins