Dner
entrez
227325
canonical
uniprot
Q8JZM4
canonical
ensembl
ENSMUSG00000036766
resolver
ensp
ENSMUSP00000042927
resolver
enst
ENSMUST00000049126
resolver
genesymbol
Dner
resolver
genesymbol_syn
Bet
resolver
genesymbol_syn
Bret
resolver
uniprot
Q3U697
resolver
uniprot
Q8R226
resolver
uniprot
Q8R4T6
resolver
uniprot
Q8VD97
resolver
uniprot_entry
DNER_MOUSE
resolver
uniprot_sec
Q3U697
resolver
uniprot_sec
Q8R226
resolver
uniprot_sec
Q8R4T6
resolver
uniprot_sec
Q8VD97
resolver
amino_acid_sequence
MPPRRAQAPGAPLLPVLALLPLLLGAGPQSGCLASPVSAAPLPAPGPCASQPCRNGGVCTPRSVTDQEHPAADAEPRYSCTCPAGVSGTYCQFVADPCASNPCHHGNCSSSSSSSSDSYLCICNDGYEGLNCEQPLPSIPTSGWTESTAPRQLQPVPATQEPDIILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVVPDVACGNASSNNSAGGRLVSFEVPQNTSVKIRQDANSLLILLWKVTATGFQQCSLIDGRSVTPLQAPGGLVLLEEMLALGPNHFIGFVNDSVAKSIVALRLTLVVKASNCVPGDSHSNDLECSGKGKCATKPSEATFSCTCQDQYIGTFCEEFDACQRKPCQNEASCIDANEKQDGSNFTCLCLPGYTGELCQSKIDYCVLDPCRNGATCVSSLSGFTCQCLEGYFGSACEEKVDPCMSSPCQNNGTCYVDGVHFTCSCSPGFTGPTCAQLVDFCALSPCAHGMCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLINGYECVCLAEYKGTHCELYKDPCANISCLNGGTCDSEGLNGTCICAPGFTGEECDIDINECDSNPCHHAGTCLDQPNGYTCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIVGICRISRIEYQGSSRPAYEEFYNCRSIDSEFSNAIASIRHARFGKKSRPAMYDVTPIAYEDYSPDDKPLVTLIKTKDL
uniprot
proteins
function
FUNCTION: Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. {ECO:0000269|PubMed:15965470, ECO:0000269|PubMed:16298139}.
uniprot
proteins
mass_dalton
78747
uniprot
proteins
mutagenesis
MUTAGEN 677; /note="Y->A: Fails to be restricted to the somatodendritic compartment."; /evidence="ECO:0000269|PubMed:11950833
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:11997712}.
uniprot
proteins
pubmed
11950833
uniprot
proteins
pubmed
11997712
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15965470
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16298139
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
737
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11950833, ECO:0000269|PubMed:11997712}; Single-pass type I membrane protein {ECO:0000269|PubMed:11950833, ECO:0000269|PubMed:11997712}. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.
uniprot
proteins
transmembrane_region
TRANSMEM 641..661; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins