ANKRD53
entrez
79998
canonical
uniprot
Q8N9V6
canonical
ensembl
ENSG00000144031
resolver
ensp
ENSP00000272421
resolver
ensp
ENSP00000353796
resolver
ensp
ENSP00000388883
resolver
ensp
ENSP00000407004
resolver
ensp
ENSP00000633714
resolver
ensp
ENSP00000712420
resolver
enst
ENST00000457410
resolver
genesymbol
ANKRD53
resolver
hgnc
HGNC:25691
resolver
uniprot
C9JZ61
resolver
uniprot
Q8IYP8
resolver
uniprot_entry
ANR53_HUMAN
resolver
uniprot_entry
C9JZ61_HUMAN
resolver
uniprot_sec
Q8IYP8
resolver
amino_acid_sequence
MASAGSTARRAGSGSWHSERGEGRGARPQPTPSGSMQQANKVSLKATWTDAESKQPSQPLPDLADHLSAQATALARPRRPASLTPPRADPSPSKESDQTAIDQTAIGSYYQLFAAAVGNVEWLRFCLNQSLREIPTDDKGFTAIHFAAQWGKLACLQVLVEEYKFPVDLLTNNSQTPLHLVIHRDNTTVALPCIYYLLEKGADLNAQTCNGSTPLHLAARDGLLDCVKVLVQSGANVHAQDAMGYKPIDFCKIWNHRACARFLKDAMWKKDKKDFAREMTKMKMFKSQLTLMEHNYLIEYQKEHKILREAAIRKWLHGKLHPGHSLVSNTKQARATALSKTPEQRESQRSRSFHPSVDARLQCIPQPTEMPKPIYRKPTVKRPTMWNVSNNPARPPTTQISHSQGIRLGVHPDPTPEHDFSSFLEVRPDGHGGARLHTVDGHWVAPVPRLPFEVLLRMLYPRVWPYRMKVPQGFYPISMREVPRKRHLGDNTFWTDTLAMNLRDTFDEAFLAAVRSHQGLPTLPSPQTNP
uniprot
proteins
function
FUNCTION: Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization. {ECO:0000269|PubMed:26820536}.
uniprot
proteins
mass_dalton
59571
uniprot
proteins
post_translational_modification
PTM: Phosphorylated during mitosis (PubMed:26820536). {ECO:0000269|PubMed:26820536}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
26820536
uniprot
proteins
sequence_length
530
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:26820536}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:26820536}. Note=Localizes at the spindle around the centrosome at prophase and prometaphase and at the spindle poles at metaphase and anaphase (PubMed:26820536). {ECO:0000269|PubMed:26820536}.
uniprot
proteins