Ano4
entrez
320091
canonical
uniprot
Q8C5H1
canonical
ensembl
ENSMUSG00000035189
resolver
ensp
ENSMUSP00000138193
resolver
ensp
ENSMUSP00000138268
resolver
ensp
ENSMUSP00000138325
resolver
ensp
ENSMUSP00000243910
resolver
ensp
ENSMUSP00000243912
resolver
ensp
ENSMUSP00000243921
resolver
ensp
ENSMUSP00000243928
resolver
enst
ENSMUST00000182613
resolver
enst
ENSMUST00000182790
resolver
genesymbol
Ano4
resolver
genesymbol_syn
Tmem16d
resolver
uniprot
Q8CA37
resolver
uniprot
S4R1L3
resolver
uniprot_entry
ANO4_MOUSE
resolver
uniprot_entry
S4R1L3_MOUSE
resolver
uniprot_sec
Q8CA37
resolver
amino_acid_sequence
MEASSSGITNGKNKVFHAEGGLDLQSHQLDMQILPDGPKSDVDFSEILNAIQEMAKDVNILFDELEAVNSPCKDDDSLLHPGNLTSTSEDTSRLEAGGETVRERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKDTFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIKTHGAVNHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATDIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGTERKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKAHHNEWP
uniprot
proteins
function
FUNCTION: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (PubMed:23532839). Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:22075693). {ECO:0000269|PubMed:22075693, ECO:0000269|PubMed:23532839}.
uniprot
proteins
mass_dalton
111544
uniprot
proteins
protein_family
Anoctamin family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20056604
uniprot
proteins
pubmed
22075693
uniprot
proteins
pubmed
22302790
uniprot
proteins
pubmed
23532839
uniprot
proteins
sequence_length
955
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q32M45}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q32M45}. Note=Shows an intracellular localization according to PubMed:22075693. {ECO:0000269|PubMed:22075693}.
uniprot
proteins
transmembrane_region
TRANSMEM 353..373; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 425..445; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 506..526; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 548..568; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 596..616; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 716..736; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 769..789; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 886..906; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins