Tsc22d3
entrez
83514
canonical
uniprot
Q9EQZ1
canonical
ensembl
ENSRNOG00000056135
resolver
ensembl
ENSRNOG00055024462
resolver
ensembl
ENSRNOG00060017420
resolver
ensembl
ENSRNOG00065025651
resolver
ensp
ENSRNOP00000072713
resolver
ensp
ENSRNOP00055034306
resolver
ensp
ENSRNOP00060024011
resolver
ensp
ENSRNOP00065036291
resolver
enst
ENSRNOT00000085118
resolver
enst
ENSRNOT00055042071
resolver
enst
ENSRNOT00060029798
resolver
enst
ENSRNOT00065044210
resolver
genesymbol
Tsc22d3
resolver
genesymbol_syn
Dsipi
resolver
genesymbol_syn
Gilz
resolver
uniprot_entry
T22D3_RAT
resolver
amino_acid_sequence
MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVALDNKIEQAMDLVKNHLMYAVREEVEVLKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSRLSPEEPAPEAPETPEAPGGSAV
uniprot
proteins
function
FUNCTION: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11 (By similarity). In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10 (By similarity). In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation and thereby NFKB1 DNA-binding activities (By similarity). In vitro, suppresses AP-1 transcription factor complex DNA-binding activities (By similarity). {ECO:0000250|UniProtKB:Q99576, ECO:0000250|UniProtKB:Q9Z2S7}.
uniprot
proteins
mass_dalton
14836
uniprot
proteins
protein_family
TSC-22/Dip/Bun family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
134
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Z2S7}. Nucleus {ECO:0000250|UniProtKB:Q9Z2S7}. Note=Localization may depend on differentiation status of myoblasts (By similarity). In undifferentiated myoblasts; localizes to the cytoplasm, but in differentiating myoblast; localizes to the nucleus (By similarity). {ECO:0000250|UniProtKB:Q9Z2S7}.
uniprot
proteins