Tdrd5
entrez
214575
canonical
uniprot
Q5VCS6
canonical
ensembl
ENSMUSG00000060985
resolver
ensp
ENSMUSP00000137182
resolver
ensp
ENSMUSP00000137298
resolver
ensp
ENSMUSP00000188624
resolver
ensp
ENSMUSP00000188625
resolver
ensp
ENSMUSP00000347809
resolver
ensp
ENSMUSP00000347810
resolver
enst
ENSMUST00000167528
resolver
genesymbol
Tdrd5
resolver
genesymbol_syn
Gm103
resolver
uniprot
A7YQ76
resolver
uniprot
D3YXM4
resolver
uniprot
J3QPB7
resolver
uniprot_entry
J3QPB7_MOUSE
resolver
uniprot_entry
TDRD5_MOUSE
resolver
uniprot_sec
A7YQ76
resolver
uniprot_sec
D3YXM4
resolver
amino_acid_sequence
MSEQERIQDCLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPGGDGTVILKAIPDESTKGIASLVAKQRRSHKVRNSMPKGRPSICSGRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFEKAFARRFGRSFQYMQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEDKQRGWPAGKVFTQPFRMKQQGSYSTGFPVMKAHFSQPISNMEPPKQVLSMAKTPTFNSVEASRLNHTEKLNQLESTFKSVIAQIGPGGTVDPELKRKIQFVVSKFPQGLFISKLLGEFELTFKEQLSPKQLGFLNVTELVGALSDILRVEFSEERQDLLVFDADLKPLPSGGPLSSVRNSCLVQPDKKTEANPWTSSLSRNSLSTVAVKKTTWDCPLKNQKEPEQKIYKKPNLVVKPLQLQVETNKPQLSLSVANHDIPPDAVRAKKLCRLPPLDTSTLVGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYIMPEYFIQPGHLCCVKISEDKWWYRVIIHRILGKKEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPAEEHWTARAILHFQKLCGLKPLVGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENAPSKGFRDFNPPALYTNASSAGDMVLTDLGHPAQQHYLNEDQEILQQAQQDINDGKCISYLKSAPKELLKDSKLSSLKTHKSCEEDPRWSILQPKDLKEENEDEVPTGMPCLESVTIGDDVWDENWLPLQAKMGKAGSPASQLFTSNLVGKKQYQTGGEMAQKDWCFSTSKDIWDDSWQPLGLANDVKGGIHTPEGPIAQEKNTSTTRIQQQPDLQYPLDSSTLPKLEEFYISLIKSQQSAERSQSEPASIQTHAGRAASKALSSTPAVGDSPENHSGSVESSPGSLKKEDVSNSRAEATAKDKSQGAIDQLSFILSPQHQISQKLYIPRSTATAVLGAAARLATSRSLLHWYPSVKGGKLEAERDGVK
uniprot
proteins
function
FUNCTION: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly. {ECO:0000269|PubMed:21383078}.
uniprot
proteins
mass_dalton
116016
uniprot
proteins
protein_family
TDRD5 family
uniprot
proteins
pubmed
15465492
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21383078
uniprot
proteins
sequence_length
1040
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21383078}. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.
uniprot
proteins