Tac3
entrez
21334
canonical
uniprot
P55099
canonical
ensembl
ENSMUSG00000025400
resolver
ensp
ENSMUSP00000026466
resolver
ensp
ENSMUSP00000136622
resolver
enst
ENSMUST00000026466
resolver
enst
ENSMUST00000179960
resolver
genesymbol
Tac3
resolver
genesymbol_syn
Nknb
resolver
genesymbol_syn
Tac2
resolver
uniprot
Q9QXS9
resolver
uniprot_entry
TKNK_MOUSE
resolver
uniprot_sec
Q9QXS9
resolver
amino_acid_sequence
MRSAMLFAAVLALSLAWTFGAVCEEPQGQGGRLSKDSDLYQLPPSLLRRLYDSRPVSLEGLLKVLSKASVGPKETSLPQKRDMHDFFVGLMGKRNSQPDTPTDVVEENTPSFGILK
uniprot
proteins
function
FUNCTION: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.; FUNCTION: [Neurokinin-B]: Is a ligand for TACR3, and triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C (By similarity). Binding to TACR3 also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP) (By similarity). Is a critical central regulator of gonadal function (By similarity). {ECO:0000250|UniProtKB:P08435, ECO:0000250|UniProtKB:Q9UHF0}.
uniprot
proteins
mass_dalton
12737
uniprot
proteins
protein_family
Tachykinin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
116
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins