Frzb
entrez
20378
canonical
uniprot
P97401
canonical
ensembl
ENSMUSG00000027004
resolver
ensp
ENSMUSP00000028389
resolver
enst
ENSMUST00000028389
resolver
genesymbol
Frzb
resolver
genesymbol_syn
Fiz
resolver
genesymbol_syn
Fre
resolver
genesymbol_syn
Frzb1
resolver
genesymbol_syn
Sfrp3
resolver
uniprot
O09075
resolver
uniprot
O09093
resolver
uniprot
Q91W58
resolver
uniprot_entry
SFRP3_MOUSE
resolver
uniprot_sec
O09075
resolver
uniprot_sec
O09093
resolver
uniprot_sec
Q91W58
resolver
amino_acid_sequence
MVCCGPGRMLLGWAGLLVLAALCLLQVPGAQAAACEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAMEQFEGLLGTHCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPESLACDELPVYDRGVCISPEAIVTADGADFPMDSSTGHCRGASSERCKCKPVRATQKTYFRNNYNYVIRAKVKEVKMKCHDVTAVVEVKEILKASLVNIPRDTVNLYTTSGCLCPPLTVNEEYVIMGYEDEERSRLLLVEGSIAEKWKDRLGKKVKRWDMKLRHLGLGKTDASDSTQNQKSGRNSNPRPARS
uniprot
proteins
function
FUNCTION: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development (By similarity). {ECO:0000250, ECO:0000269|PubMed:9178261}.
uniprot
proteins
mass_dalton
36011
uniprot
proteins
protein_family
Secreted frizzled-related protein (sFRP) family
uniprot
proteins
pubmed
11452312
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19188438
uniprot
proteins
pubmed
9096311
uniprot
proteins
pubmed
9118218
uniprot
proteins
pubmed
9178261
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins