PGLYRP4
entrez
57115
canonical
uniprot
Q96LB8
canonical
ensembl
ENSG00000163218
resolver
ensp
ENSP00000352672
resolver
ensp
ENSP00000357728
resolver
genesymbol
PGLYRP4
resolver
genesymbol_syn
PGRPIB
resolver
hgnc
HGNC:30015
resolver
uniprot
A8K838
resolver
uniprot
Q3B822
resolver
uniprot
Q3B823
resolver
uniprot
Q5SY63
resolver
uniprot
Q5SY64
resolver
uniprot
Q9HD75
resolver
uniprot_entry
PGRP4_HUMAN
resolver
uniprot_sec
A8K838
resolver
uniprot_sec
Q3B822
resolver
uniprot_sec
Q3B823
resolver
uniprot_sec
Q5SY63
resolver
uniprot_sec
Q5SY64
resolver
uniprot_sec
Q9HD75
resolver
amino_acid_sequence
MLPWLLVFSALGIQAWGDSSWNKTQAKQVSEGLQYLFENISQLTEKGLPTDVSTTVSRKAWGAEAVGCSIQLTTPVNVLVIHHVPGLECHDQTVCSQRLRELQAHHVHNNSGCDVAYNFLVGDDGRVYEGVGWNIQGVHTQGYNNISLGFAFFGTKKGHSPSPAALSAMENLITYAVQKGHLSSSYVQPLLGKGENCLAPRQKTSLKKACPGVVPRSVWGARETHCPRMTLPAKYGIIIHTAGRTCNISDECRLLVRDIQSFYIDRLKSCDIGYNFLVGQDGAIYEGVGWNVQGSSTPGYDDIALGITFMGTFTGIPPNAAALEAAQDLIQCAMVKGYLTPNYLLVGHSDVARTLSPGQALYNIISTWPHFKH
uniprot
proteins
function
FUNCTION: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. {ECO:0000269|PubMed:16354652}.
uniprot
proteins
mass_dalton
40620
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:16354652}.
uniprot
proteins
protein_family
N-acetylmuramoyl-L-alanine amidase 2 family
uniprot
proteins
pubmed
11461926
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16354652
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17502600
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16354652}.
uniprot
proteins