Fez1
entrez
81730
canonical
uniprot
P97577
canonical
ensembl
ENSRNOG00000006075
resolver
ensembl
ENSRNOG00055009280
resolver
ensembl
ENSRNOG00060012011
resolver
ensembl
ENSRNOG00065016663
resolver
ensp
ENSRNOP00000008285
resolver
ensp
ENSRNOP00000101366
resolver
ensp
ENSRNOP00055012614
resolver
ensp
ENSRNOP00060016023
resolver
ensp
ENSRNOP00065021895
resolver
enst
ENSRNOT00000129566
resolver
enst
ENSRNOT00055015701
resolver
enst
ENSRNOT00060020363
resolver
enst
ENSRNOT00065027774
resolver
genesymbol
Fez1
resolver
uniprot
Q62922
resolver
uniprot_entry
FEZ1_RAT
resolver
uniprot_sec
Q62922
resolver
amino_acid_sequence
MEAPLVSLDEEFEDIRPCCTEDPEEKPQSLYGTSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLRDEEVWDALTDNYIPSLSEDWRDPNIEALNGNSSDTEIHEKEEEDEFIEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEVEVLEEEDGGEISSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVHQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGADRQYLNTVIPYEKKSSPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYILKVLCPT
uniprot
proteins
function
FUNCTION: May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. May participate in the transport of mitochondria and other cargos along microtubules. {ECO:0000269|PubMed:17173861, ECO:0000269|PubMed:17669366}.
uniprot
proteins
mass_dalton
45244
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by protein kinase C zeta; which enhances interaction with UBE4B and polyubiquitination. {ECO:0000269|PubMed:9971736}.; PTM: Polyubiquitinated in a UBE4B-dependent manner; which does not lead to proteasomal degradation and may be important for neurogenic activity. Polyubiquitin linkage seems to be mainly through Lys-26 (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Zygin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17173861
uniprot
proteins
pubmed
17669366
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9971736
uniprot
proteins
sequence_length
393
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell membrane. Note=Colocalizes with both, alpha- and gamma-tubulin (By similarity). Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta. {ECO:0000250}.
uniprot
proteins