Lgi4
entrez
243914
canonical
uniprot
Q8K1S1
canonical
ensembl
ENSMUSG00000036560
resolver
ensp
ENSMUSP00000041579
resolver
enst
ENSMUST00000039775
resolver
genesymbol
Lgi4
resolver
genesymbol_syn
Lgil3
resolver
uniprot
Q8K4Y8
resolver
uniprot_entry
LGI4_MOUSE
resolver
uniprot_sec
Q8K4Y8
resolver
amino_acid_sequence
MGGAGILLFLLAWAGAGVAWSPPKGKCPPHCSCSKENTLCEGSPELPESFSTTLLSLSLVRMGVSRLKAGSFLKMPSLHLLLFTSNTFSVIEGDAFIGLSYLQYLFIEDNKIGSISKNALRGLRSLTHLSLANNHLEALPRFLFRGLETLTHVDLRGNPFQCDCRVLWLLQWMPTVNASVGTGACAGPPAVAQIQLNHLDPKKFKCRATELSWLQTVGESALSVESFSYQGEPHMVLAQPFAGRCLILVWDYSLQRFRPEEELSAPSVVSCKPLVLGPRLFILAARLWGGSQLWSRSSPDLRLTPVQVLAPQRLLRPNDAELLWLDGQPCFVVADASKAGSTTLLCRDGPGFYPRQSLHAWHRDTDAEALELDGRPHLLLASASQRPVLFHWVGGRFERRTDIPEAEDVYATKHFQAGGDVFLCLTRYIGDSMVMRWDGSMFRLLQQLPSRGSHVFQPLLIARDQLAILGSDFAFSQVFRFESDKGILEPLQELGPPALVAPRAFAQVTVAGRRFLFAACFKGPTQIYQHHELDLSA
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in Lgi4 are the cause of the claw paw (clp) phenotype. Mice are characterized by limb posture abnormalities and peripheral hypomyelination, with no sign of dysmyelination in the CNS. {ECO:0000269|PubMed:16341215}.
uniprot
proteins
function
FUNCTION: Component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation. {ECO:0000269|PubMed:16341215}.
uniprot
proteins
mass_dalton
59377
uniprot
proteins
pubmed
12095917
uniprot
proteins
pubmed
12217514
uniprot
proteins
pubmed
16341215
uniprot
proteins
pubmed
18974846
uniprot
proteins
pubmed
19833108
uniprot
proteins
sequence_length
537
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins