PPM1H
entrez
57460
canonical
uniprot
Q9ULR3
canonical
ensembl
ENSG00000111110
resolver
ensp
ENSP00000228705
resolver
enst
ENST00000228705
resolver
genesymbol
PPM1H
resolver
genesymbol_syn
ARHCL1
resolver
genesymbol_syn
KIAA1157
resolver
genesymbol_syn
URCC2
resolver
hgnc
HGNC:18583
resolver
uniprot
B1Q2A9
resolver
uniprot
B2RXG4
resolver
uniprot
Q6PI86
resolver
uniprot_entry
PPM1H_HUMAN
resolver
uniprot_sec
B1Q2A9
resolver
uniprot_sec
B2RXG4
resolver
uniprot_sec
Q6PI86
resolver
amino_acid_sequence
MLTRVKSAVANFMGGIMAGSSGSEHGGGSCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
function
FUNCTION: Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation. {ECO:0000269|PubMed:22586611}.
uniprot
proteins
mass_dalton
56448
uniprot
proteins
mutagenesis
MUTAGEN 153; /note="H->L: Decreased enzymatic activity."; /evidence="ECO:0000269|PubMed:22586611
uniprot
proteins
protein_family
PP2C family
uniprot
proteins
pubmed
10574461
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22586611
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
514
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:22586611}. Cytoplasm {ECO:0000269|PubMed:22586611}.
uniprot
proteins