Ramp2
entrez
54409
canonical
uniprot
Q9WUP0
canonical
ensembl
ENSMUSG00000001240
resolver
ensp
ENSMUSP00000122072
resolver
enst
ENSMUST00000129680
resolver
genesymbol
Ramp2
resolver
uniprot
Q6IS25
resolver
uniprot_entry
RAMP2_MOUSE
resolver
uniprot_sec
Q6IS25
resolver
amino_acid_sequence
MAPLRVERAPGGSRLGVTRAQRPTALCLPPLLLLLLLLLGAVSASPESLNQSLPESQNQSHPTEDSLVSKGKMEDYETHVLPCWYEYKSCMDSVKDWCNWTLISRHYSDLQNCLEYNADKFGLGFPNPLAENIILEAHLIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLVTLVVWRSKDSDAQA
uniprot
proteins
function
FUNCTION: Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed:10854696). Required for the transport of CALCRL to the plasma membrane (By similarity). Together with CALCRL, form a receptor complex for adrenomedullin/ADM (PubMed:10854696). Together with CALCR, act as a receptor complex for calcitonin/CT/CALC. Together with CALCR, also act as a receptor complex for amylin/IAPP (By similarity). {ECO:0000250|UniProtKB:O60895, ECO:0000269|PubMed:10854696}.
uniprot
proteins
mass_dalton
21017
uniprot
proteins
protein_family
RAMP family
uniprot
proteins
pubmed
10777702
uniprot
proteins
pubmed
10854696
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
189
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O60895}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:O60895}.
uniprot
proteins
transmembrane_region
TRANSMEM 158..179; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O60895
uniprot
proteins