Dimt1
entrez
66254
canonical
uniprot
Q9D0D4
canonical
ensembl
ENSMUSG00000021692
resolver
ensp
ENSMUSP00000022203
resolver
enst
ENSMUST00000022203
resolver
genesymbol
Dimt1
resolver
genesymbol_syn
Dimt1l
resolver
uniprot
Q3TTJ5
resolver
uniprot
Q8BVH8
resolver
uniprot_entry
DIM1_MOUSE
resolver
uniprot_sec
Q3TTJ5
resolver
uniprot_sec
Q8BVH8
resolver
amino_acid_sequence
MPKAKSAASSRRRDRQEQRRELKRAGGLMFNTGIGQHILKNPLIVNSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPLASKLQVLVGDVLKSDLPFFDACVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVQNTVIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS
uniprot
proteins
ec_number
2.1.1.183
uniprot
proteins
function
FUNCTION: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. {ECO:0000250|UniProtKB:Q9UNQ2}.
uniprot
proteins
mass_dalton
35274
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
rRNA adenine N(6)-methyltransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
313
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9UNQ2}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9UNQ2}.
uniprot
proteins