Sh3tc2
entrez
225608
canonical
uniprot
Q80VA5
canonical
ensembl
ENSMUSG00000045629
resolver
ensp
ENSMUSP00000055094
resolver
ensp
ENSMUSP00000157442
resolver
ensp
ENSMUSP00000158088
resolver
ensp
ENSMUSP00000158542
resolver
enst
ENSMUST00000235860
resolver
genesymbol
Sh3tc2
resolver
genesymbol_syn
Kiaa1985
resolver
uniprot
A0A494B911
resolver
uniprot
Q3UPD8
resolver
uniprot
Q6DFU9
resolver
uniprot
Q8BWH2
resolver
uniprot
Q8BXB8
resolver
uniprot
Q8C0G6
resolver
uniprot_entry
A0A494B911_MOUSE
resolver
uniprot_entry
Q3UPD8_MOUSE
resolver
uniprot_entry
Q6DFU9_MOUSE
resolver
uniprot_entry
S3TC2_MOUSE
resolver
uniprot_sec
Q8BWH2
resolver
uniprot_sec
Q8BXB8
resolver
uniprot_sec
Q8C0G6
resolver
amino_acid_sequence
MGGCFCIPGERSLPWGPGKEGSSKDPPGLAEDTSSLENKRKCFLPQNMTQDLVLSFCVKSRSRRCVNAALQEAARRRLWALENEAQEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSICLEHLFFDHTYWLNSRLVDDTEIQVSVDDNHLENIYLGLLLQEGHFFCRAVCSVAQPADKEGEYLTLCKNELISVLSGGESECEAMSLVTGQRGLVPMSALEPLPVPFHQWFLKNHPGICGLPRKRDWTGSGQIGRGRCKALMDYEQEERDELCFLQGESIDVIGFVIPGLQWFIGKSVSSGEVGFVPTRSIDLDSCSPMSKNSAFFSDEERSSLWSPGSERKAECSGFLCSLAHTDITSIYRLSEFEAIQNLQNDLSASQPEGFREARSGGTWMERQTIGSRRSSGSGDSSPEEDELISASSDSYHLPEPEDLDDPELFMDLSTSLEEDDVEHFAPILAFLDHEGYTDHFKSLYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMSHMTWAHARLCFLLGRLSIRKTKLSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPTLLEKAGALLACLPDHEFSTKNELDVVTYVLRQGIVVGSGLLEARSCFLAIRLLLSLGRHEEVVPFAERLQLLSGHPPASEATATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSLSIWQAYLVLQNATKILGVPSSNWCEVSALACPTLRQALAACEELSDQDIQRTLCLILSKMYLQHQSPDGSVHYLSQAHVLGKLLGEEEAFESSLCLAWAYLLGRQTEKALEILEPLLCSLRETECVTQRGVVHNLLGLAFEDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCMQQSARGYLLQAVRLYSELQASKETDMELVQVLLWLGQASVSGHQLVHSRLCYEMALLFGLRHQHLSSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGQLLESLGQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVELYLQEAIQTALRSEEPSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALRTELRIFNKLTELQISLEGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKDAHDATEYFLLALAAAVLMGDEELQNTIKNRLDSICQSPLWHSNPFGCSSERARWLSGGSLAL
uniprot
proteins
function
FUNCTION: Is involved in nerve myelination and is required for the integrity of nodes of Ranvier (PubMed:19805030). It probably functions as a Rab effector in the regulation of endocytic recycling (By similarity). {ECO:0000250|UniProtKB:Q8TF17, ECO:0000269|PubMed:19805030}.
uniprot
proteins
mass_dalton
145144
uniprot
proteins
mutagenesis
MUTAGEN 2; /note="G->A: Loss of myristoylation. The mutant does not localize to the cell membrane."; /evidence="ECO:0000269|PubMed:19805030
uniprot
proteins
post_translational_modification
PTM: Myristoylated; myristoylation is required for localization to the cell membrane. {ECO:0000269|PubMed:19805030}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19805030
uniprot
proteins
pubmed
20826437
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1289
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19805030}. Recycling endosome {ECO:0000269|PubMed:19805030}.
uniprot
proteins