Lat2
entrez
317676
canonical
uniprot
Q8CGL2
canonical
ensembl
ENSRNOG00000021856
resolver
ensembl
ENSRNOG00065001581
resolver
ensp
ENSRNOP00000031304
resolver
ensp
ENSRNOP00000083189
resolver
ensp
ENSRNOP00065001473
resolver
enst
ENSRNOT00000034629
resolver
enst
ENSRNOT00065002114
resolver
genesymbol
Lat2
resolver
genesymbol_syn
Lab
resolver
genesymbol_syn
Ntal
resolver
genesymbol_syn
Wbscr5
resolver
uniprot
G3V8Z1
resolver
uniprot_entry
G3V8Z1_RAT
resolver
uniprot_entry
NTAL_RAT
resolver
amino_acid_sequence
MNAELELLWPLSGLLLLLLLGTTAWLCVQCSRPGVKRNEKIYEQRNQQENEQSVASSQTYSLARPVRTGLQMDAASNKSFERKNKLLFSHLEGPESPRYQNFYKGSRRESDAAYVDPIPTDYYNWGCFQKPPEDNDSNSYENVLICKPSTPESGTEESEDYQNSVSILQWRESKRTMGARTSPSGSPDEEPDYVNGDVATTEKI
uniprot
proteins
function
FUNCTION: Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
23130
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosines following cross-linking of BCR in B-cells, high affinity IgG receptor (FCGR1) in myeloid cells, or high affinity IgE receptor (FCER1) in mast cells; which induces the recruitment of GRB2.
uniprot
proteins
sequence_length
204
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Note=Present in lipid rafts. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins