Smg9
entrez
71997
canonical
uniprot
Q9DB90
canonical
ensembl
ENSMUSG00000002210
resolver
ensp
ENSMUSP00000002280
resolver
ensp
ENSMUSP00000242468
resolver
ensp
ENSMUSP00000326236
resolver
genesymbol
Smg9
resolver
uniprot
Q3TTB9
resolver
uniprot
Q8BYJ3
resolver
uniprot_entry
SMG9_MOUSE
resolver
uniprot_sec
Q3TTB9
resolver
uniprot_sec
Q8BYJ3
resolver
amino_acid_sequence
MSESGHSQPGLYGIERRRRWKEPGSSGPQNLSGPGGRERDYIAPWERERRDGSEDPSTNVMQKTPIILSKPPAERSKQPPPSTAPAAPPAPAPLEKPIVLMKPREEGKGPVAGTGASTPEGTAPPPPTAPAPPKGEKEGQRPTQPVYQIQNRGMGTAAPTAMDPVVGQAKLLPPERMKHSIKLVDDQMNWCDSAIEYLLDQTDVLVVGVLGLQGTGKSMVMSLLSANTPEEDQRAYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSAGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHLMIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDAEVNLFLVPFMDSEAENENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMSMARPQLSHTILTEKNWFHYAARIWDGVKKSSALAEYSRLLA
uniprot
proteins
function
FUNCTION: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (By similarity). Plays a role in brain, heart, and eye development (PubMed:27018474). {ECO:0000250|UniProtKB:Q9H0W8, ECO:0000269|PubMed:27018474}.
uniprot
proteins
mass_dalton
57621
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SMG1. {ECO:0000250|UniProtKB:Q9H0W8}.
uniprot
proteins
protein_family
SMG9 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27018474
uniprot
proteins
sequence_length
520
uniprot
proteins