Ebf1
entrez
116543
canonical
uniprot
Q63398
canonical
ensembl
ENSRNOG00000028845
resolver
ensp
ENSRNOP00000067433
resolver
ensp
ENSRNOP00000068319
resolver
ensp
ENSRNOP00000105851
resolver
enst
ENSRNOT00000071435
resolver
enst
ENSRNOT00000076664
resolver
enst
ENSRNOT00000128797
resolver
genesymbol
Ebf1
resolver
genesymbol_syn
Coe1
resolver
genesymbol_syn
Ebf
resolver
genesymbol_syn
Olf1
resolver
uniprot
A0A8L2QZ79
resolver
uniprot
A0ABK0LJF7
resolver
uniprot
M0RCU9
resolver
uniprot_entry
A0A8L2QZ79_RAT
resolver
uniprot_entry
A0ABK0LJF7_RAT
resolver
uniprot_entry
COE1_RAT
resolver
uniprot_entry
M0RCU9_RAT
resolver
amino_acid_sequence
MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM
uniprot
proteins
function
FUNCTION: Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold. {ECO:0000250|UniProtKB:Q07802}.
uniprot
proteins
mass_dalton
63650
uniprot
proteins
protein_family
COE family
uniprot
proteins
pubmed
8321284
uniprot
proteins
pubmed
9151733
uniprot
proteins
sequence_length
584
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins