RSMC
entrez
102288414
canonical
uniprot
E9PRG8
canonical
ensembl
ENSG00000278615
resolver
ensp
ENSP00000432523
resolver
enst
ENST00000524958
resolver
genesymbol
RSMC
resolver
genesymbol_syn
C11orf98
resolver
hgnc
HGNC:51238
resolver
uniprot
A0A0B4J220
resolver
uniprot_entry
RSMC_HUMAN
resolver
uniprot_sec
A0A0B4J220
resolver
amino_acid_sequence
MGAPGGKINRPRTELKKKLFKRRRVLNRERRLRHRVVGAVIDQGLITRHHLKKRASSARANITLSGKKRRKLLQQIRLAQKEKTAMEVEAPSKPARTSEPQLKRQKKTKAPQDVEMKDLEDES
uniprot
proteins
function
FUNCTION: Promotes sister chromatid cohesion by enhancing recruitment of CDCA5/sororin to chromatin during S phase and stimulating the anti-WAPL activity of CDCA5 (PubMed:41261216). Associates with the pre-60S ribosome and may be involved in pre-60S ribosome assembly (PubMed:37491604). {ECO:0000269|PubMed:37491604, ECO:0000269|PubMed:41261216}.
uniprot
proteins
mass_dalton
14234
uniprot
proteins
post_translational_modification
PTM: ADP-ribosylated by PARP1 during S phase; this enhances the interaction between RSMC and CDCA5/sororin. {ECO:0000269|PubMed:41261216}.
uniprot
proteins
protein_family
RSMC family
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
28589727
uniprot
proteins
pubmed
37491604
uniprot
proteins
pubmed
41261216
uniprot
proteins
sequence_length
123
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:41261216}. Nucleus, nucleolus {ECO:0000269|PubMed:28589727}.
uniprot
proteins