CTCFL
entrez
140690
canonical
uniprot
Q8NI51
canonical
ensembl
ENSG00000124092
resolver
ensp
ENSP00000243914
resolver
ensp
ENSP00000360239
resolver
ensp
ENSP00000392034
resolver
ensp
ENSP00000399061
resolver
ensp
ENSP00000409344
resolver
ensp
ENSP00000415329
resolver
ensp
ENSP00000415579
resolver
ensp
ENSP00000437999
resolver
ensp
ENSP00000439998
resolver
ensp
ENSP00000476398
resolver
ensp
ENSP00000476458
resolver
ensp
ENSP00000476577
resolver
ensp
ENSP00000476718
resolver
ensp
ENSP00000476783
resolver
ensp
ENSP00000477165
resolver
ensp
ENSP00000477488
resolver
ensp
ENSP00000583463
resolver
ensp
ENSP00000754335
resolver
enst
ENST00000481655
resolver
enst
ENST00000608158
resolver
enst
ENST00000608425
resolver
genesymbol
CTCFL
resolver
genesymbol_syn
BORIS
resolver
hgnc
HGNC:16234
resolver
uniprot
A0S6W1
resolver
uniprot
A1L4C6
resolver
uniprot
A6XGL8
resolver
uniprot
A6XGM0
resolver
uniprot
A6XGM2
resolver
uniprot
A6XGM3
resolver
uniprot
A6XGM8
resolver
uniprot
A6XGM9
resolver
uniprot
A6XGN0
resolver
uniprot
A6XGN1
resolver
uniprot
A6XGN2
resolver
uniprot
A6XGN3
resolver
uniprot
A6XGN4
resolver
uniprot
E7EQ27
resolver
uniprot
E7EUE3
resolver
uniprot
E9PBA9
resolver
uniprot
Q5JUG4
resolver
uniprot
Q9BZ30
resolver
uniprot
Q9NQJ3
resolver
uniprot
V9GY73
resolver
uniprot
V9GYX4
resolver
uniprot_entry
A6XGM0_HUMAN
resolver
uniprot_entry
A6XGM9_HUMAN
resolver
uniprot_entry
CTCFL_HUMAN
resolver
uniprot_entry
V9GY73_HUMAN
resolver
uniprot_entry
V9GYX4_HUMAN
resolver
uniprot_sec
A0S6W1
resolver
uniprot_sec
A1L4C6
resolver
uniprot_sec
A6XGL8
resolver
uniprot_sec
A6XGM2
resolver
uniprot_sec
A6XGM3
resolver
uniprot_sec
A6XGM8
resolver
uniprot_sec
A6XGN0
resolver
uniprot_sec
A6XGN1
resolver
uniprot_sec
A6XGN2
resolver
uniprot_sec
A6XGN3
resolver
uniprot_sec
A6XGN4
resolver
uniprot_sec
E7EQ27
resolver
uniprot_sec
E7EUE3
resolver
uniprot_sec
E9PBA9
resolver
uniprot_sec
Q5JUG4
resolver
uniprot_sec
Q9BZ30
resolver
uniprot_sec
Q9NQJ3
resolver
amino_acid_sequence
MAATEISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGAFQDSVLEEEVELVLAPSEESEKYILTLQTVHFTSEAVELQDMSLLSIQQQEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISIQQELYSPQEMEVLQFHALEENVMVASEDSKLAVSLAETTGLIKLEEEQEKNQLLAERTKEQLFFVETMSGDERSDEIVLTVSNSNVEEQEDQPTAGQADAEKAKSTKNQRKTKGAKGTFHCDVCMFTSSRMSSFNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTRPYKCNDCNMAFVTSGELVRHRRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQCCQCSYASRDTYKLKRHMRTHSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCPHCATIIARKSDLRVHMRNLHAYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHCSYACKQERHMTAHIRTHTGEKPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKCGKGFSRWINLHRHSEKCGSGEAKSAASGKGRRTRKRKQTILKEATKGQKEAAKGWKEAANGDEAAAEEASTTKGEQFPGEMFPVACRETTARVKEEVDEGVTCEMLLNTMDK
uniprot
proteins
function
FUNCTION: Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters. {ECO:0000250, ECO:0000269|PubMed:12011441, ECO:0000269|PubMed:18413740, ECO:0000269|PubMed:18765639}.
uniprot
proteins
mass_dalton
75747
uniprot
proteins
protein_family
CTCF zinc-finger protein family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
12011441
uniprot
proteins
pubmed
12191639
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17048991
uniprot
proteins
pubmed
17962299
uniprot
proteins
pubmed
18413740
uniprot
proteins
pubmed
18765639
uniprot
proteins
sequence_length
663
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
uniprot
proteins