Stx12
entrez
65033
canonical
uniprot
G3V7P1
canonical
ensembl
ENSRNOG00000011804
resolver
ensembl
ENSRNOG00055028713
resolver
ensembl
ENSRNOG00060026981
resolver
ensembl
ENSRNOG00065028787
resolver
ensp
ENSRNOP00000017227
resolver
ensp
ENSRNOP00000106779
resolver
ensp
ENSRNOP00055040929
resolver
ensp
ENSRNOP00060038968
resolver
ensp
ENSRNOP00065040794
resolver
enst
ENSRNOT00000017227
resolver
enst
ENSRNOT00000145273
resolver
enst
ENSRNOT00055049729
resolver
enst
ENSRNOT00060046861
resolver
enst
ENSRNOT00065049693
resolver
genesymbol
Stx12
resolver
genesymbol_syn
Stx13
resolver
uniprot
A0ABK0LX74
resolver
uniprot
O70319
resolver
uniprot
O88385
resolver
uniprot_entry
A0ABK0LX74_RAT
resolver
uniprot_entry
STX12_RAT
resolver
uniprot_sec
O70319
resolver
uniprot_sec
O88385
resolver
amino_acid_sequence
MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQFQHSTNQLAKETNELLKELGSLPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQDLELIKERETAIQQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERASDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK
uniprot
proteins
function
FUNCTION: SNARE promoting fusion of transport vesicles with target membranes (PubMed:17159904, PubMed:30962439). Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway (PubMed:30962439). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (PubMed:16037816). {ECO:0000269|PubMed:16037816, ECO:0000269|PubMed:17159904, ECO:0000269|PubMed:30962439}.
uniprot
proteins
mass_dalton
31187
uniprot
proteins
protein_family
Syntaxin family
uniprot
proteins
pubmed
12070131
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
16037816
uniprot
proteins
pubmed
17159904
uniprot
proteins
pubmed
20098723
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
30962439
uniprot
proteins
pubmed
9507000
uniprot
proteins
pubmed
9553086
uniprot
proteins
sequence_length
274
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane; Single-pass type IV membrane protein {ECO:0000269|PubMed:9553086}. Golgi apparatus membrane; Single-pass type IV membrane protein {ECO:0000269|PubMed:9553086}. Endomembrane system {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Early endosome membrane {ECO:0000269|PubMed:20098723}; Single-pass type IV membrane protein {ECO:0000305}. Recycling endosome membrane {ECO:0000269|PubMed:20098723, ECO:0000269|PubMed:30962439, ECO:0000269|PubMed:9553086}; Single-pass type IV membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 251..271; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins