Hyou1
entrez
192235
canonical
uniprot
Q63617
canonical
ensembl
ENSRNOG00000010944
resolver
ensp
ENSRNOP00000039172
resolver
genesymbol
Hyou1
resolver
genesymbol_syn
Hsph4
resolver
genesymbol_syn
Orp150
resolver
uniprot
F1LN18
resolver
uniprot
Q6P136
resolver
uniprot_entry
HYOU1_RAT
resolver
uniprot_entry
Q6P136_RAT
resolver
uniprot_sec
F1LN18
resolver
amino_acid_sequence
MAATVRRQRPRRLLCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVTVTLKENERFLGDSAAGMAIKNPKATLRYFQHLLGKQADNPHVALYRSRFPEHELNVDPQRQTVRFQISPQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPAFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINSTAQNIMFYDMGSGSTVCTIVTYQTVKTKEAGTQPQLQIRGVGFDRTLGGLEMELRLREHLAKLFNEQRKGQKAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFDRVPGPVQQALQSAEMSLDQIEQVILVGGPTRVPKVQEVLLKPVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSPEEESTLTKLGNTISSLFGGGTSSDAKENGTDAVQEEEESPAEGSKDEPAEQGELKEEAEAPMEDTSQPPPSEPKGDAAREGETPDEKESGDKSEAQKPNEKGQAGPEGVPPAPEEEKKQKPARKQKMVEEIGVELAVLDLPDLPEDELAHSVQKLEDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSATSTWLEDEGFGATTVMLKDKLAELRKLCQGLFFRVEERRKWPERLSALDNLLNHSSIFLKGARLIPEMDQIFTDVEMTTLEKVINDTWTWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRTEPPLNASAGDQEEKVIPPTGQTEEAKAILEPDKEGLGTEAADSEPLELGGPGAESEQAEQTAGQKRPLKNDEL
uniprot
proteins
function
FUNCTION: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. Promotes HSPA5/BiP-mediated ATP nucleotide exchange and thereby activates the unfolded protein response (UPR) pathway in the presence of endoplasmic reticulum stress (By similarity). May play a role as a molecular chaperone and participate in protein folding (By similarity). {ECO:0000250, ECO:0000250|UniProtKB:Q9JKR6}.
uniprot
proteins
mass_dalton
111289
uniprot
proteins
protein_family
Heat shock protein 70 family
uniprot
proteins
pubmed
12475965
uniprot
proteins
pubmed
24090084
uniprot
proteins
pubmed
8617779
uniprot
proteins
pubmed
9020069
uniprot
proteins
sequence_length
999
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen.
uniprot
proteins