NFIC
entrez
4782
canonical
uniprot
P08651
canonical
ensembl
ENSG00000141905
resolver
ensp
ENSP00000342194
resolver
ensp
ENSP00000378543
resolver
ensp
ENSP00000396843
resolver
ensp
ENSP00000465655
resolver
ensp
ENSP00000466647
resolver
genesymbol
NFIC
resolver
genesymbol_syn
NFI
resolver
hgnc
HGNC:7786
resolver
uniprot
A8K1H0
resolver
uniprot
B7Z4T6
resolver
uniprot
B7Z4U5
resolver
uniprot
B7Z9C3
resolver
uniprot
K7EMU1
resolver
uniprot
P08652
resolver
uniprot
Q14932
resolver
uniprot
Q9UPJ3
resolver
uniprot
Q9UPJ9
resolver
uniprot
Q9UPK0
resolver
uniprot
Q9UPK1
resolver
uniprot_entry
B7Z4T6_HUMAN
resolver
uniprot_entry
NFIC_HUMAN
resolver
uniprot_sec
A8K1H0
resolver
uniprot_sec
B7Z4U5
resolver
uniprot_sec
B7Z9C3
resolver
uniprot_sec
K7EMU1
resolver
uniprot_sec
P08652
resolver
uniprot_sec
Q14932
resolver
uniprot_sec
Q9UPJ3
resolver
uniprot_sec
Q9UPJ9
resolver
uniprot_sec
Q9UPK0
resolver
uniprot_sec
Q9UPK1
resolver
amino_acid_sequence
MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDPAGIYQAQSWYLG
uniprot
proteins
function
FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Promotes telomerase reverse transcriptase transcription (PubMed:35198878). {ECO:0000269|PubMed:35198878}.
uniprot
proteins
mass_dalton
55675
uniprot
proteins
mutagenesis
MUTAGEN 65; /note="K->R: Partial loss of ubiquitination."; /evidence="ECO:0000269|PubMed:35198878"; MUTAGEN 99; /note="K->R: Partial loss of ubiquitination."; /evidence="ECO:0000269|PubMed:35198878
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated via 'Lys-63'-linked chains, leading to enhanced telomerase reverse transcriptase transcription. {ECO:0000269|PubMed:35198878}.
uniprot
proteins
protein_family
CTF/NF-I family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
31375868
uniprot
proteins
pubmed
3398920
uniprot
proteins
pubmed
35198878
uniprot
proteins
pubmed
8710515
uniprot
proteins
sequence_length
508
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins