Prss8
entrez
192107
canonical
uniprot
Q9ES87
canonical
ensembl
ENSRNOG00000019616
resolver
ensp
ENSRNOP00000026572
resolver
ensp
ENSRNOP00000086587
resolver
enst
ENSRNOT00000026572
resolver
enst
ENSRNOT00000094049
resolver
genesymbol
Prss8
resolver
uniprot
A0A8I6A1I1
resolver
uniprot
F1MA37
resolver
uniprot
Q6GSY8
resolver
uniprot
Q9ER01
resolver
uniprot_entry
A0A8I6A1I1_RAT
resolver
uniprot_entry
F1MA37_RAT
resolver
uniprot_entry
PRSS8_RAT
resolver
uniprot_sec
Q6GSY8
resolver
uniprot_sec
Q9ER01
resolver
amino_acid_sequence
MALRVGLGLGQLEALFVLLLIGLLQSRIGADGTEASCGAVIQPRITGGGSAKPGQWPWQVSITYNGVHVCGGSLVSNQWVVSAAHCFPREHSKEEYEVKLGAHQLDSFSNDIVVHTVAQIISHSSYREEGSQGDIALIRLSSPVTFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYNINAVPEEPHTIQQDMLCAGYVKGGKDACQGDSGGPLSCPIDGLWYLAGIVSWGDACGAPNRPGVYTLTSTYASWIHHHVAELQPRVVPQTQESQPDGHLCNHHPVFNLAAAQKLSRPILFLPLSLTLGLFSLWLEH
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G) (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
36857
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
11373334
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
342
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Prostasin]: Secreted, extracellular space {ECO:0000250}.; SUBCELLULAR LOCATION: [Prostasin light chain]: Secreted, extracellular space {ECO:0000250}. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus. {ECO:0000250}.; SUBCELLULAR LOCATION: [Prostasin heavy chain]: Secreted, extracellular space {ECO:0000250}. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 320..340; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins