Cyp7b1
entrez
25429
canonical
uniprot
Q63688
canonical
ensembl
ENSRNOG00000009730
resolver
ensp
ENSRNOP00000073111
resolver
genesymbol
Cyp7b1
resolver
uniprot_entry
CP7B1_RAT
resolver
amino_acid_sequence
ALEYQYVMKNPKQLSFEKFSRRLSAKAFSVKKLLTNDDLSNDIHRGYLLLQGKSLDGLLETMIQEVKEIFESRLLKLTDWNTARVFDFCSSLVFEITFTTIYGKILAANKKQIISELRDDFLKFDDHFPYLVSDIPIQLLRNAEFMQKKIIKCLTPEKVAQMQRRSEIVQERQEMLKKYYGHEEFEIGAHHLGLLWASLANTIPAMFWAMYYLLQHPEAMEVLRDEIDSFLQSTGQKKGPGISVHFTREQLDSLVCLESAILEVLRLCSYSSIIREVQEDMDFSSESRSYRLRKGDFVAVFPPMIHNDPEVFDAPKDFRFDRFVEDGKKKTTFFKGGKKLKSYIIPFGLGTSKCPGRYFAINEMKLLVIILLTYFDLEVIDTKPIGLNHSRMFLGIQHPDSDISFRYKAKSWRS
uniprot
proteins
ec_number
1.14.14.29
uniprot
proteins
function
FUNCTION: Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25-hydroxycholesterol. Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. {ECO:0000250|UniProtKB:Q60991}.
uniprot
proteins
mass_dalton
48227
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; bile acid biosynthesis.
uniprot
proteins
protein_family
Cytochrome P450 family
uniprot
proteins
pubmed
12759897
uniprot
proteins
pubmed
8530364
uniprot
proteins
sequence_length
414
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
uniprot
proteins