Cecr2
entrez
330409
canonical
uniprot
E9Q2Z1
canonical
ensembl
ENSMUSG00000071226
resolver
ensp
ENSMUSP00000098556
resolver
ensp
ENSMUSP00000108306
resolver
genesymbol
Cecr2
resolver
genesymbol_syn
Kiaa1740
resolver
uniprot
E9QA25
resolver
uniprot
F6VR46
resolver
uniprot
F7B218
resolver
uniprot
Q6PAQ2
resolver
uniprot
Q6ZPI9
resolver
uniprot_entry
CECR2_MOUSE
resolver
uniprot_sec
E9QA25
resolver
uniprot_sec
F6VR46
resolver
uniprot_sec
F7B218
resolver
uniprot_sec
Q6PAQ2
resolver
uniprot_sec
Q6ZPI9
resolver
amino_acid_sequence
MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGRSNGELSLCRESERQKNVSNVPGKTGKRRGRPPKRKKLQEEIISSEKQEENSLTSDLQTRNGSRGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKPELQHRFMSDHLSIKSIKLEETPMLTKIEKQKRREEEEERQLLLAVQKKEQEQMLKEERKREMEEKVKAVEDRAKRRKLREERAWLLAQGKELPPELSHLDLNSPMREGKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKIPMDISSMEKKLNGGLYCNKEEFVNDMKTMFRNCRKYNGDSSEYTKMSDNLERCFHRAMTKHFPGEDGDTDEEFWIKEDEKREKRRSRSGRSSGSHVWTRSRDTEGSSRKQPPVENGGKSLPPARRAASSGDDQSRSSIQLPPEVGTSHGQGFSRPLHCGRVPSHAPPLNQMRPAAPGTFGSLQGSDPTNLHGSSRIPEAPPGEPLQHPPFAIQAPVGISNHRGSLLSAPDLSNMGSHVPSLQLGQMNCPSQDGNMYPPAPFQAGFIPSRHGGTPARPPDFPESSEIPPGHIYHSYKYLNRAHPAVWNGNHGTTNPGRLGPDEKPHLGPGPSHHPHTLGHMMDGRVMRQPIPPNQWTKQSSFLPHGVPSSGYMQPPCKSAGHRLQPPPTPAPSPRFRGPSQALRGAQGGESMMDSPEMIAMQQLSSRVCPPGVPYHPRQPTPPQLPGPFPQVAHSASVCVSAPKPALDNPGSTQEMTETHEPEEDPAEPLPGHEEKAASICSSEGVYLKQLPHPAPPLQASCTRQSSPQERETEDSQLKSDASDSADTYKTSKNKNTWPLDNSYSSPAVQGCLRDLSIVAETGNLPENGVVGEASPCRSEGKGLDGSGSEKPLCPRGKTLQEAVPCTGPNATTPPCTDPSLMAATVNQFSPLYMPGIEYSNSATQYPMSPSLQGLASMMGGKSSGSQPQSFPPRGFQANGPHPGLFPRYRPQQGMRYSYQPPSQPSYHPYQRTPYYTCPQGFSDWQRSLPSQRSPSGPPGSHPPRSLFSEKNVLSSLQGCETLNTALTSPTQMDVVTAKVVPPDGHNSGPEEEKMDESVERPESPKEFLDLDNHNAATKRQNSLSTSDYLYGTPPPSLSSGMTFGSSAFPPHSVMLQTGSPYTPQRSASHFQPRAYPSPVPAHPPPHPVATQPNGLSPEDSLYCCQEEGLGHFQASMMEQTGTGSGLRGSFQEVHRPPGLQMHPVQSQSLFPKTPAPAASPEQLPPHKTPTLPLDQS
uniprot
proteins
function
FUNCTION: Regulatory subunit of the ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair (By similarity). The complexes do not have the ability to slide mononucleosomes to the center of a DNA template (By similarity). The CERF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the CERF-5 ISWI chromatin remodeling complex (By similarity). Plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development (PubMed:15640247, PubMed:20589882, PubMed:21246654). In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes (PubMed:22154806). In histone-modifying complexes, CECR2 recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (By similarity). May also be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis (By similarity). {ECO:0000250|UniProtKB:Q9BXF3, ECO:0000269|PubMed:15640247, ECO:0000269|PubMed:20589882, ECO:0000269|PubMed:21246654, ECO:0000269|PubMed:22154806}.
uniprot
proteins
mass_dalton
161530
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15640247
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20589882
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21246654
uniprot
proteins
pubmed
22154806
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
34197713
uniprot
proteins
sequence_length
1453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:34197713}.
uniprot
proteins