Cckar
entrez
24889
canonical
uniprot
P30551
canonical
ensembl
ENSRNOG00000043124
resolver
ensembl
ENSRNOG00060015710
resolver
ensp
ENSRNOP00000063137
resolver
ensp
ENSRNOP00060021578
resolver
enst
ENSRNOT00060026909
resolver
genesymbol
Cckar
resolver
uniprot_entry
CCKAR_RAT
resolver
amino_acid_sequence
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
uniprot
proteins
function
FUNCTION: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. {ECO:0000269|PubMed:7654260}.
uniprot
proteins
mass_dalton
49657
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12916469
uniprot
proteins
pubmed
1313582
uniprot
proteins
pubmed
7654260
uniprot
proteins
pubmed
8024583
uniprot
proteins
sequence_length
444
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 57..82; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 93..119; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 131..152; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 173..193; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 226..249; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 330..350; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 366..389; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins