Rbbp7
entrez
245688
canonical
uniprot
Q60973
canonical
ensembl
ENSMUSG00000031353
resolver
ensp
ENSMUSP00000033720
resolver
ensp
ENSMUSP00000329280
resolver
enst
ENSMUST00000033720
resolver
genesymbol
Rbbp7
resolver
genesymbol_syn
Rbap46
resolver
uniprot
A2AFJ0
resolver
uniprot
Q3UX20
resolver
uniprot
Q3UX53
resolver
uniprot
Q8C5H3
resolver
uniprot_entry
Q3UX53_MOUSE
resolver
uniprot_entry
Q8C5H3_MOUSE
resolver
uniprot_entry
RBBP7_MOUSE
resolver
uniprot_sec
A2AFJ0
resolver
uniprot_sec
Q3UX20
resolver
amino_acid_sequence
MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTASELEGQGS
uniprot
proteins
function
FUNCTION: Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex (By similarity). {ECO:0000250|UniProtKB:Q16576}.
uniprot
proteins
mass_dalton
47790
uniprot
proteins
protein_family
WD repeat RBAP46/RBAP48/MSI1 family
uniprot
proteins
pubmed
10984530
uniprot
proteins
pubmed
11788710
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20144788
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
27806305
uniprot
proteins
pubmed
34180153
uniprot
proteins
pubmed
7503932
uniprot
proteins
sequence_length
425
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins