Amigo1
entrez
295365
canonical
uniprot
Q80ZD7
canonical
ensembl
ENSRNOG00000045665
resolver
ensembl
ENSRNOG00055020836
resolver
ensembl
ENSRNOG00060027117
resolver
ensembl
ENSRNOG00065023718
resolver
ensp
ENSRNOP00000066608
resolver
ensp
ENSRNOP00000100732
resolver
ensp
ENSRNOP00000109871
resolver
ensp
ENSRNOP00055028845
resolver
ensp
ENSRNOP00060039110
resolver
ensp
ENSRNOP00065033135
resolver
enst
ENSRNOT00000074725
resolver
enst
ENSRNOT00000148498
resolver
enst
ENSRNOT00000156175
resolver
enst
ENSRNOT00055035565
resolver
enst
ENSRNOT00060047026
resolver
enst
ENSRNOT00065040644
resolver
genesymbol
Amigo1
resolver
genesymbol_syn
Ali2
resolver
genesymbol_syn
Amigo
resolver
uniprot_entry
AMGO1_RAT
resolver
amino_acid_sequence
MQPQRDLRGLWLLLLSLFLLLFEVARAGRPVVSCPANCLCASNILSCSKQQLPNVPQSLPGYTALLDLSHNNLSRLKAEWTPTRLTNLHSLLLSHNHLNFISSEAFVPVPNLRYLDLSSNHLHTLDEFLFSGLQALEVLLLYNNHIVVVDRNAFEDMAQLQKLYLSQNMISRFPLELIKDANRLPKLTLLDLSSNKLKKLPLTDLQKLPAWVKNGLYLHNNPLECDCKLYQLFSHWQYRQLSSVMDFQEDLYCVHSKKLHNVFSLDFFNCSEYKESAWEAHLGDTLTITCDTKQQGMTKVWVTPSNEQVLNQGANGTVTVSEDGNLHFKEVQVEDGGVYTCYAMGETFNETLSVELKVYNFTLHGHHDTLNTAYTTLVGCILSVVLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSSMLSTTPNHDPMAGGDKDDGFDRRVAFLEPAGPGQGQNGKLKPGNTLPVPEATGKGQRRMSDPESVSSVFSDTPIVV
uniprot
proteins
function
FUNCTION: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (PubMed:12629050). Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (By similarity). {ECO:0000250|UniProtKB:Q80ZD8, ECO:0000269|PubMed:12629050, ECO:0000303|PubMed:12629050}.
uniprot
proteins
mass_dalton
55283
uniprot
proteins
protein_family
AMIGO family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12629050
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
493
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q80ZD8}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q80ZD8}. Perikaryon {ECO:0000250|UniProtKB:Q80ZD8}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q80ZD8}. Cell projection, axon {ECO:0000269|PubMed:12629050}. Note=Associated with axons of neuronal cells (PubMed:12629050). Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal and cortical neurons (By similarity). {ECO:0000250|UniProtKB:Q80ZD8}.
uniprot
proteins
transmembrane_region
TRANSMEM 373..393; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins