Plekhh2
entrez
213556
canonical
uniprot
Q8C115
canonical
ensembl
ENSMUSG00000040852
resolver
ensp
ENSMUSP00000039628
resolver
ensp
ENSMUSP00000279722
resolver
ensp
ENSMUSP00000279723
resolver
genesymbol
Plekhh2
resolver
genesymbol_syn
Kiaa2028
resolver
uniprot
B2RQ85
resolver
uniprot
Q059P2
resolver
uniprot
Q69Z29
resolver
uniprot
Q8VDL8
resolver
uniprot_entry
PKHH2_MOUSE
resolver
uniprot_sec
B2RQ85
resolver
uniprot_sec
Q059P2
resolver
uniprot_sec
Q69Z29
resolver
uniprot_sec
Q8VDL8
resolver
amino_acid_sequence
MEEPSEPEGLIDWKERCVALEAQLMKFRVQASKIRELLADKMQQLERQVIDAERQAEKAFQEVQVMEEKLKAANIQTSESETRLYKKCQDLESVMQEKDDIIQNLALRLEEQKQVRIQEAKIIEEKAAKIKEWVTVKLNELEVENQNLRFINQTQTEEIRAIQSKLQELQEKKISCVSSPKTSEGQRNLTFGCFLSRAKSPPCVVRCEEVSKMASNEPEITEGRCVEEMEIAEKPADNQVQENSRSQRKLHETSCSSEQNQKTRASFAMDGGTSQNSGVPVSDWSSDEDDGSKGRSKSRCTSTLSSHTSEEGGQCGRLGSEAYLTASDDSSSIFEEETFDGNRPEQKKLCSWQQKAPWKAQGNLAKGRSQSGVKEQDSSSDELNKKFHSQRLDYTSSSSEANTPSPILTPALTPRYPNSLPGKGGAPLVPPPFQPPPKLRVPNVFSISVALTKRHLSQPQLCSDRMFGTNRNAISMIRPLRPQETDLDVVDGDGAEAVNRMDTGCDDGLFSYDSQDPPPCADDQENSEAPKKAPCNKPPTPPLHRFPSWESRIYAVAKSGIRVSEAFNMEHANKNSADILSYSAASLYTSLIYKNMTTPVYTTLKGKATQISSSPFLDDSSGSDEEDSSRSSSRLSESDARSRSGPSSPRAMKRGVSDSSAASESDYAIPPDAYPIDAECSQPEQKLLKTCLASCDNGKNEPLEKSGYLLKMSVRVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLATEKHTYYLTADSPNILEEWIKVLQSVLRVQAANPLCLQPEGKPAVKGLLTKVKHGYSKRVWCMLVGKVLYYFRNQEDKFPLGQLKLWEAKVEEVDRSCDSDEDYETRGCYLLSTHYTIIVHPKDQGPTYLLIGSKHEKEAWLYHLTVAAGSNNINVGSEFEQLVCKLLNIEGEPSSQIWRHPMLCHSKEGILSPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHISLAQSALQVCLTHPELQNEICCQLIKQTRRRQLQNQPGPLQGWQLLALCVGLFLPHHPFLWLLQLHLQRNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSRPFSIPVHFMNGLYQVVGFDASTTVEEFLNTLNQDTGMRKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKEQQPGKCEGSRTVRLTYKNRLYFSVQARGETDREKTLLLYQTNDQIINGLFPLNKDLALEMAALLAQVDIGDFERPFSTPAGPVTNQCKANQTLKQVIERFYPKRYREGCSEEQLRQLYQRLSTKWMALRGHSAADCIRIYLTVARKWPFFGAKLFFAKPIAPSSLGNNCVWLAVHENGLSILEYTSMRLVTSYMYKGLMTFGGYQEDFMVVVSTQSKDRPTEKLLFAMAKHKILEITLLIASYINSFHQQKTTFHHLSAPALLSPRTQAPQARVMGSQPPLSNSRPTKGPTLL
uniprot
proteins
function
FUNCTION: In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia. {ECO:0000269|PubMed:22832517}.
uniprot
proteins
mass_dalton
167733
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17251388
uniprot
proteins
pubmed
22832517
uniprot
proteins
sequence_length
1491
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17251388}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=Localizes to the slit diaphragm and foot process of podocytes. Localization to peripheral regions of lamellipodia seems to be dependent on PI3K (By similarity). {ECO:0000250}.
uniprot
proteins