FAM168B
entrez
130074
canonical
uniprot
A1KXE4
canonical
ensembl
ENSG00000152102
resolver
ensp
ENSP00000374565
resolver
ensp
ENSP00000387051
resolver
ensp
ENSP00000564447
resolver
ensp
ENSP00000564448
resolver
ensp
ENSP00000564456
resolver
ensp
ENSP00000564460
resolver
ensp
ENSP00000564463
resolver
ensp
ENSP00000564464
resolver
ensp
ENSP00000564466
resolver
ensp
ENSP00000564471
resolver
ensp
ENSP00000600155
resolver
ensp
ENSP00000624342
resolver
genesymbol
FAM168B
resolver
genesymbol_syn
KIAA0280L
resolver
genesymbol_syn
MANI
resolver
hgnc
HGNC:27016
resolver
uniprot
Q2TAZ6
resolver
uniprot
Q6NZ40
resolver
uniprot_entry
F168B_HUMAN
resolver
uniprot_sec
Q2TAZ6
resolver
uniprot_sec
Q6NZ40
resolver
amino_acid_sequence
MNPVYSPGSSGVPYANAKGIGYPAGFPMGYAAAAPAYSPNMYPGANPTFQTGYTPGTPYKVSCSPTSGAVPPYSSSPNPYQTAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPIPPPRGNGVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW
uniprot
proteins
function
FUNCTION: Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27. {ECO:0000250|UniProtKB:D4AEP3}.
uniprot
proteins
mass_dalton
20324
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:D4AEP3}.
uniprot
proteins
protein_family
FAM168 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20716133
uniprot
proteins
pubmed
22771904
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
195
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:D4AEP3}. Cell membrane {ECO:0000250|UniProtKB:Q80XQ8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q80XQ8}. Cell projection, axon {ECO:0000250|UniProtKB:Q80XQ8}. Note=Expressed in neuronal cell bodies and axonal fibers. {ECO:0000250|UniProtKB:Q80XQ8}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 143..164; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins