Htr4
entrez
15562
canonical
uniprot
P97288
canonical
ensembl
ENSMUSG00000026322
resolver
ensp
ENSMUSP00000027560
resolver
ensp
ENSMUSP00000157470
resolver
ensp
ENSMUSP00000157967
resolver
ensp
ENSMUSP00000157982
resolver
ensp
ENSMUSP00000271651
resolver
ensp
ENSMUSP00000271652
resolver
ensp
ENSMUSP00000271653
resolver
enst
ENSMUST00000237114
resolver
genesymbol
Htr4
resolver
uniprot
A0A494BA82
resolver
uniprot
O89003
resolver
uniprot
O89004
resolver
uniprot
Q3URB5
resolver
uniprot
Q9R2A4
resolver
uniprot_entry
5HT4R_MOUSE
resolver
uniprot_entry
A0A494BA82_MOUSE
resolver
uniprot_sec
O89003
resolver
uniprot_sec
O89004
resolver
uniprot_sec
Q3URB5
resolver
uniprot_sec
Q9R2A4
resolver
amino_acid_sequence
MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT
uniprot
proteins
function
FUNCTION: G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (By similarity). HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity (By similarity). {ECO:0000250|UniProtKB:Q13639}.
uniprot
proteins
mass_dalton
43962
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10220570
uniprot
proteins
pubmed
15466885
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
8946946
uniprot
proteins
pubmed
9928238
uniprot
proteins
sequence_length
388
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q13639}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:15466885}; Multi-pass membrane protein {ECO:0000255}. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with NHERF1 and EZR might target the protein to specialized subcellular regions, such as microvilli. {ECO:0000269|PubMed:15466885}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..44; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q13639"; TRANSMEM 55..78; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q13639"; TRANSMEM 93..117; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q13639"; TRANSMEM 134..157; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q13639"; TRANSMEM 189..212; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q13639"; TRANSMEM 258..283; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q13639"; TRANSMEM 291..314; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q13639
uniprot
proteins