Smarcal1
entrez
54380
canonical
uniprot
Q8BJL0
canonical
ensembl
ENSMUSG00000039354
resolver
ensp
ENSMUSP00000047589
resolver
ensp
ENSMUSP00000137833
resolver
ensp
ENSMUSP00000194178
resolver
ensp
ENSMUSP00000194182
resolver
ensp
ENSMUSP00000194185
resolver
ensp
ENSMUSP00000194192
resolver
genesymbol
Smarcal1
resolver
genesymbol_syn
Harp
resolver
uniprot
Q3TEQ9
resolver
uniprot
Q3U4W0
resolver
uniprot
Q3V3A8
resolver
uniprot
Q8BVK7
resolver
uniprot
Q8BXW4
resolver
uniprot
Q8K309
resolver
uniprot
Q9EQK8
resolver
uniprot
Q9QYC4
resolver
uniprot_entry
SMAL1_MOUSE
resolver
uniprot_sec
Q3TEQ9
resolver
uniprot_sec
Q3U4W0
resolver
uniprot_sec
Q3V3A8
resolver
uniprot_sec
Q8BVK7
resolver
uniprot_sec
Q8BXW4
resolver
uniprot_sec
Q8K309
resolver
uniprot_sec
Q9EQK8
resolver
uniprot_sec
Q9QYC4
resolver
amino_acid_sequence
MSLPLTEEQRKKIEENRQKALARRAEKLSEQPQSAASGSSAAGPSQSKQGSLLNLLAEPSKPVGHASIFKQQNLSNSFPTDQRPHSSRCSQPSPAEETTGLWKTQGEMSTACPKPNPSPPGASNQPLLGYKSSEGQPQATWDTGASSSGPFPRDPELEAKAARPSTSRQSISDSFYVLGGKTPRTEGRPPNILQTTPQNTGFLRGACIKTGDRFRVKIGYNQELIAVFKSLPSRHYDSFTKTWDFSMSDYRALMKAVERLSTVSLKPLDEAGGSVGGQTSLPSAPSLTFVTGKCMLISRVRFEVDIGYSEAVIGLFKQMESRSYDIKTRKWSFLLEEHNKLIARSRELKQVQLDPLPKTVTLAFASQLEKTSPKLKADVPEADLSGVDAKLVSSLMPFQREGVSFAISKRGRLLLADDMGLGKTVQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPENINVVVTGKGRLTAGLVNIVSFDLLCKLERQLKTPFKVVIIDESHFLKNIKTARCRAAVPILKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRLPWGWDYSGSSNLGELKLLLEEAIMLRRLKSDVLSQLPAKQRKMVVVNPGRISSRAKAALDAAAKEMTKDKTKQQQKEALLVFFNRTAEAKIPCVVEYILDLLDSGREKFLVFAHHKVILDAVAKELERKNVQHIRIDGSTPSADREAQCQRFQLSKGHTVALLSITAANMGLTFSTADLVVFAELFWNPGVLIQAEDRVHRIGQTNSVSIHYLVAKGTADDYLWPLIQEKIKVLGEAGLSETNFSEMTEATDYVHKDPKQKTIYDLFQQSFEDDGNDMEFLEAAESFELGSTSGTSGNISQDLGDLLDEDEGSPPKKSRFEFFDNWDSFSSPF
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
ec_number
5.6.2.-
uniprot
proteins
function
FUNCTION: ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks. {ECO:0000250|UniProtKB:Q9NZC9}.
uniprot
proteins
mass_dalton
100840
uniprot
proteins
post_translational_modification
PTM: DNA damage-regulated phosphorylation by kinases that may include ATM, ATR and PRKDC. {ECO:0000250}.
uniprot
proteins
protein_family
SMARCAL1 subfamily
uniprot
proteins
protein_family
SNF2/RAD54 helicase family
uniprot
proteins
pubmed
10857751
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
910
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NZC9}. Note=Recruited to damaged DNA regions. {ECO:0000250|UniProtKB:Q9NZC9}.
uniprot
proteins