Rasa4
entrez
54153
canonical
uniprot
Q6PFQ7
canonical
ensembl
ENSMUSG00000004952
resolver
ensp
ENSMUSP00000037869
resolver
ensp
ENSMUSP00000098136
resolver
genesymbol
Rasa4
resolver
genesymbol_syn
Capri
resolver
genesymbol_syn
Kiaa0538
resolver
uniprot
Q2PMI6
resolver
uniprot
Q3U2R4
resolver
uniprot
Q571H1
resolver
uniprot
Q58DY7
resolver
uniprot_entry
RASL2_MOUSE
resolver
uniprot_sec
Q2PMI6
resolver
uniprot_sec
Q3U2R4
resolver
uniprot_sec
Q571H1
resolver
uniprot_sec
Q58DY7
resolver
amino_acid_sequence
MAKRSSLSIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEDYQVHLPPTFHTVAFYVMDEDALSRDDVIGKVCLTRDALASHPKGFSGWTHLVEVDPNEEVQGEIHLRLEVVPGVHASRLRCAVLEARDLAPKDRNGASDPFVRVHYNGRTQETSVVKKSCYPRWNETFDFELEKGASEALLVEAWDWDLVSRNDFLGKVAVNVQRLCSAQQEEGWFRLQPDQSKSRQGKGNLGSLQLEVRLRDETVLPSVCYQPLVQLLCQEVKLGTQGPGRLIPVIEETTSAECRQEVATTLLKLFLGQGLAKDFLDLLFQLELGRTSEANTLFRSNSLASKSMESFLKVAGMRYLHGILGPIIDRVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLVALLSAICRSVRTCPAIIRATFRQLFRRVRERFPNAQHQNVPFIAVTSFLCLRFFSPAILSPKLFHLRERHADARTSRTLLLLAKAVQNIGNMDTPVSRAKESWMEPLQPTVRQGVAQLKDFIMKLVDIEEKEELDLQRALNSQAPPVKEGPLFIHRTKGKGPLASSSFKKLYFSLTTEALSFAKTSSSKKSTFIKLASIRAAEKVEEKSFGSSHIMQVIYADDVGRAQTVYLQCKCVNELNQWLSALRKASTNNRGLLRSYHPGIFRGDKWSCCHQKDKTDQGCDKTHSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAALRERYQLLRGATEAGVSPTGCDGAPEDSLAQLLRVLQDLREAHGSSLASPAAREPHHLLELQT
uniprot
proteins
function
FUNCTION: Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. Isoform 2 activates the Ras pathway and promotes RANKL shedding by modulating the expression of MMP14. {ECO:0000269|PubMed:16041389, ECO:0000269|PubMed:16234249}.
uniprot
proteins
mass_dalton
90060
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16041389
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16234249
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
802
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane.
uniprot
proteins