CYTIP
entrez
9595
canonical
uniprot
O60759
canonical
ensembl
ENSG00000115165
resolver
ensp
ENSP00000264192
resolver
genesymbol
CYTIP
resolver
genesymbol_syn
PSCDBP
resolver
hgnc
HGNC:9506
resolver
uniprot
B4DWH9
resolver
uniprot
Q15630
resolver
uniprot
Q8NE32
resolver
uniprot_entry
CYTIP_HUMAN
resolver
uniprot_sec
B4DWH9
resolver
uniprot_sec
Q15630
resolver
uniprot_sec
Q8NE32
resolver
amino_acid_sequence
MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSRRNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF
uniprot
proteins
function
FUNCTION: By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
uniprot
proteins
mass_dalton
40010
uniprot
proteins
mutagenesis
MUTAGEN 82; /note="K->E: No membrane-association. No change in the binding to CYTH1; when associated with A-90 and A-92."; /evidence="ECO:0000269|PubMed:12606567"; MUTAGEN 90; /note="F->A: No membrane-association. No change in the binding to CYTH1; when associated with E-82 and A-92."; /evidence="ECO:0000269|PubMed:12606567"; MUTAGEN 92; /note="I->A: No membrane-association. No change in the binding to CYTH1; when associated with E-82 and A-90."; /evidence="ECO:0000269|PubMed:12606567
uniprot
proteins
pubmed
11867758
uniprot
proteins
pubmed
12606567
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17577583
uniprot
proteins
pubmed
21248752
uniprot
proteins
pubmed
8241278
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Early endosome. Note=Recruited from the cytosol to endosomes by SNX27.
uniprot
proteins