Ildr2
entrez
100039795
canonical
uniprot
B5TVM2
canonical
ensembl
ENSMUSG00000040612
resolver
ensp
ENSMUSP00000107047
resolver
ensp
ENSMUSP00000141323
resolver
ensp
ENSMUSP00000141502
resolver
ensp
ENSMUSP00000142152
resolver
ensp
ENSMUSP00000142240
resolver
ensp
ENSMUSP00000142311
resolver
ensp
ENSMUSP00000274501
resolver
ensp
ENSMUSP00000274502
resolver
enst
ENSMUST00000192638
resolver
enst
ENSMUST00000192732
resolver
enst
ENSMUST00000193860
resolver
enst
ENSMUST00000194964
resolver
enst
ENSMUST00000195557
resolver
genesymbol
Ildr2
resolver
genesymbol_syn
D1Ertd471e
resolver
genesymbol_syn
Ll
resolver
uniprot
A0A0A6YVY9
resolver
uniprot
A0A0A6YWD2
resolver
uniprot
A0A0A6YXV2
resolver
uniprot
A0A0A6YY19
resolver
uniprot
A0A0A6YY76
resolver
uniprot
B5TVM3
resolver
uniprot
B5TVM4
resolver
uniprot
B5TVM5
resolver
uniprot
B5TVM6
resolver
uniprot
B5TVM7
resolver
uniprot
B5TVM8
resolver
uniprot
B5TVM9
resolver
uniprot
E9Q9U5
resolver
uniprot_entry
A0A0A6YVY9_MOUSE
resolver
uniprot_entry
A0A0A6YWD2_MOUSE
resolver
uniprot_entry
A0A0A6YXV2_MOUSE
resolver
uniprot_entry
A0A0A6YY19_MOUSE
resolver
uniprot_entry
A0A0A6YY76_MOUSE
resolver
uniprot_entry
ILDR2_MOUSE
resolver
uniprot_sec
B5TVM3
resolver
uniprot_sec
B5TVM4
resolver
uniprot_sec
B5TVM5
resolver
uniprot_sec
B5TVM6
resolver
uniprot_sec
B5TVM7
resolver
uniprot_sec
B5TVM8
resolver
uniprot_sec
B5TVM9
resolver
uniprot_sec
E9Q9U5
resolver
amino_acid_sequence
MPAFPTLDLDGKLGKMDRVVLGWTAVFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKSYCQDRMGESLGMSSPRAQALSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIMPEWVFVGLVILGIFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHDDDSNFRQSYHQMRNKQFPMSGDLESNPDYWSGVMGGNSGTNRGPALEYNKEDRESFRHSQQRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRSRRANGNSHEARAGSRFERSESRAHGAFYQDGSLDEYYGRGRSREPPGDGERGWTYSPAPARRRPPEDAPLPRLVSRTPGTAPKYDHSYLSSVLERQARPESSSRGGSLETPSKLGAQLGPRSASYYAWSPPTTYKAGASEGEDEDDAADEDALPPYSELELSRGELSRGPSYRGRDLSFHSNSEKRRKKEPAKKPGDFPTRMSLVV
uniprot
proteins
function
FUNCTION: May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion (PubMed:23826244, PubMed:33863978). With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions (PubMed:23239027). Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity (PubMed:29431694). In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1 (PubMed:28785060). {ECO:0000269|PubMed:23239027, ECO:0000269|PubMed:23826244, ECO:0000269|PubMed:28785060, ECO:0000269|PubMed:29431694, ECO:0000269|PubMed:33863978}.
uniprot
proteins
mass_dalton
73235
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
protein_family
LISCH7 family
uniprot
proteins
pubmed
18654634
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23239027
uniprot
proteins
pubmed
23826244
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
28785060
uniprot
proteins
pubmed
29431694
uniprot
proteins
pubmed
33863978
uniprot
proteins
sequence_length
661
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23826244}; Single-pass type I membrane protein {ECO:0000269|PubMed:23826244}. Cell junction, tight junction {ECO:0000269|PubMed:23239027}. Nucleus {ECO:0000269|PubMed:28785060}.
uniprot
proteins
transmembrane_region
TRANSMEM 202..222; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins