MZT1
entrez
440145
canonical
uniprot
Q08AG7
canonical
ensembl
ENSG00000204899
resolver
ensp
ENSP00000367049
resolver
enst
ENST00000377818
resolver
genesymbol
MZT1
resolver
genesymbol_syn
C13orf37
resolver
genesymbol_syn
MOZART1
resolver
hgnc
HGNC:33830
resolver
uniprot
Q5W0P5
resolver
uniprot_entry
MZT1_HUMAN
resolver
uniprot_sec
Q5W0P5
resolver
amino_acid_sequence
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEALSSVIKELRKATEALKAAENMTS
uniprot
proteins
function
FUNCTION: Required for the recruitment and the assembly of the gamma-tubulin ring complex (gTuRC) at the centrosome (PubMed:20360068, PubMed:38609661, PubMed:39321809). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed:38609661, PubMed:39321809). {ECO:0000269|PubMed:20360068, ECO:0000269|PubMed:38609661, ECO:0000269|PubMed:39321809}.
uniprot
proteins
mass_dalton
8479
uniprot
proteins
protein_family
MOZART1 family
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20360068
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
38609661
uniprot
proteins
pubmed
39321809
uniprot
proteins
sequence_length
82
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20360068}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:20360068}.
uniprot
proteins