B3GNT8
entrez
374907
canonical
uniprot
Q7Z7M8
canonical
ensembl
ENSG00000177191
resolver
ensp
ENSP00000312700
resolver
ensp
ENSP00000510371
resolver
enst
ENST00000321702
resolver
enst
ENST00000691102
resolver
genesymbol
B3GNT8
resolver
genesymbol_syn
B3GALT7
resolver
genesymbol_syn
BGALT15
resolver
hgnc
HGNC:24139
resolver
uniprot_entry
B3GN8_HUMAN
resolver
amino_acid_sequence
MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPTLPANLSTRLGQTIPLPFAYWNQQQWRLGSLPSGDSTETGGCQAWGAAAATEIPDFASYPKDLRRFLLSAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWGSPAPGIRLLFLLGSPVGEAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVSFVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEGGYPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYTGLCIRALGLVPQAHPGFLTAWPADRTADHCAFRNLLLVRPLGPQASIRLWKQLQDPRLQC
uniprot
proteins
ec_number
2.4.1.149
uniprot
proteins
function
FUNCTION: Beta-1,3-N-acetylglucosaminyltransferase that functions in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans. {ECO:0000269|PubMed:15620693, ECO:0000269|PubMed:15917431, ECO:0000269|PubMed:18826941}.
uniprot
proteins
mass_dalton
43396
uniprot
proteins
mutagenesis
MUTAGEN 246; /note="Q->A: Loss of enzymatic activity, no loss of B3GNT2-binding and activation."; /evidence="ECO:0000269|PubMed:18826941
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000269|PubMed:15917431, ECO:0000269|PubMed:18826941}.
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
15486459
uniprot
proteins
pubmed
15620693
uniprot
proteins
pubmed
15917431
uniprot
proteins
pubmed
18826941
uniprot
proteins
sequence_length
397
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9NY97}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9NY97}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..23; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins