Tcea2
entrez
21400
canonical
uniprot
Q9QVN7
canonical
ensembl
ENSMUSG00000059540
resolver
ensp
ENSMUSP00000099331
resolver
ensp
ENSMUSP00000119646
resolver
enst
ENSMUST00000103042
resolver
genesymbol
Tcea2
resolver
uniprot
O08667
resolver
uniprot
Q6P072
resolver
uniprot
Q810R3
resolver
uniprot_entry
Q810R3_MOUSE
resolver
uniprot_entry
TCEA2_MOUSE
resolver
uniprot_sec
O08667
resolver
uniprot_sec
Q6P072
resolver
amino_acid_sequence
MGKEEEIARIARRLDKMVTRKNAEGAMDLLRELKNMPITLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKSRNQGRGTPLPTSSSKDASRTTDLSCKKPDPPRTPSTPRITTFPQVPITCDAVRNKCREMLTLALQTDHDHVAVGVNCEHLSSQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCNKCRKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKFC
uniprot
proteins
function
FUNCTION: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
uniprot
proteins
mass_dalton
33663
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the BCR(BACURD3) E3 ubiquitin ligase complex, at least composed of CUL3, KCTD10/BACURD3 and RBX1; leading to proteasomal degradation and RNAP complex remodeling. {ECO:0000250|UniProtKB:Q15560}.
uniprot
proteins
protein_family
TFS-II family
uniprot
proteins
pubmed
8641458
uniprot
proteins
pubmed
9133631
uniprot
proteins
pubmed
9799847
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins