Max
entrez
17187
canonical
uniprot
P28574
canonical
ensembl
ENSMUSG00000059436
resolver
ensp
ENSMUSP00000080778
resolver
ensp
ENSMUSP00000106025
resolver
ensp
ENSMUSP00000151710
resolver
ensp
ENSMUSP00000240463
resolver
enst
ENSMUST00000218640
resolver
genesymbol
Max
resolver
genesymbol_syn
Myn
resolver
uniprot
A0A1W2P7P4
resolver
uniprot
B2RS19
resolver
uniprot
Q8C4Y1
resolver
uniprot_entry
A0A1W2P7P4_MOUSE
resolver
uniprot_entry
MAX_MOUSE
resolver
uniprot_sec
B2RS19
resolver
uniprot_sec
Q8C4Y1
resolver
amino_acid_sequence
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDGGSDSSSESEPEEPQSRKKLRMEAS
uniprot
proteins
function
FUNCTION: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. CpG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC:MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements (By similarity). {ECO:0000250|UniProtKB:P61244}.
uniprot
proteins
mass_dalton
18245
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000305}.
uniprot
proteins
protein_family
MAX family
uniprot
proteins
pubmed
12391307
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
1840505
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9680483
uniprot
proteins
sequence_length
160
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cell projection, dendrite {ECO:0000250}.
uniprot
proteins