Sox15
entrez
20670
canonical
uniprot
P43267
canonical
ensembl
ENSMUSG00000041287
resolver
ensp
ENSMUSP00000048524
resolver
enst
ENSMUST00000047373
resolver
genesymbol
Sox15
resolver
genesymbol_syn
Sox-15
resolver
genesymbol_syn
Sox16
resolver
uniprot
O70204
resolver
uniprot
P70418
resolver
uniprot
Q5F2B2
resolver
uniprot
Q62246
resolver
uniprot
Q62247
resolver
uniprot
Q91V00
resolver
uniprot
Q91V43
resolver
uniprot
Q920T1
resolver
uniprot
Q9JLG2
resolver
uniprot_entry
Q5F2B2_MOUSE
resolver
uniprot_entry
SOX15_MOUSE
resolver
uniprot_sec
O70204
resolver
uniprot_sec
P70418
resolver
uniprot_sec
Q62246
resolver
uniprot_sec
Q62247
resolver
uniprot_sec
Q91V00
resolver
uniprot_sec
Q91V43
resolver
uniprot_sec
Q920T1
resolver
uniprot_sec
Q9JLG2
resolver
amino_acid_sequence
MALTSSSQAETWSLHPRASTASLPLGPQEQEAGGSPGASGGLPLEKVKRPMNAFMVWSSVQRRQMAQQNPKMHNSEISKRLGAQWKLLGDEEKRPFVEEAKRLRARHLRDYPDYKYRPRRKSKNSSTGSVPFSQEGGGLACGGSHWGPGYTTTQGSRGFGYQPPNYSTAYLPGSYTSSHCRPEAPLPCTFPQSDPRLQGELRPSFSPYLSPDSSTPYNTSLAGAPMPVTHL
uniprot
proteins
function
FUNCTION: Transcription factor that binds to DNA at the 5'-AACAATG-3' consensus sequence (PubMed:10821863, PubMed:15863505, PubMed:16759287, PubMed:17363903). Acts as a transcriptional activator and repressor (PubMed:10821863, PubMed:15863505, PubMed:16759287). Binds synergistically with POU5F1 (OCT3/4) to gene promoters (PubMed:15863505). Binds to the FOXK1 promoter and recruits FHL3, resulting in transcriptional activation of FOXK1 which leads to myoblast proliferation (PubMed:17363903). Acts as an inhibitor of myoblast differentiation via transcriptional repression which leads to down-regulation of the muscle-specific genes MYOD and MYOG (PubMed:10821863). Involved in trophoblast giant cell differentiation via enhancement of HAND1 transcriptional activity (PubMed:16759287). Regulates transcription of HRC via binding to its proximal enhancer region (PubMed:15863505). Involved in skeletal muscle regeneration (PubMed:15367664, PubMed:17363903). Also plays a role in the development of myogenic precursor cells (PubMed:15367664). {ECO:0000269|PubMed:10821863, ECO:0000269|PubMed:15367664, ECO:0000269|PubMed:15863505, ECO:0000269|PubMed:16759287, ECO:0000269|PubMed:17363903}.
uniprot
proteins
mass_dalton
25311
uniprot
proteins
pubmed
10524236
uniprot
proteins
pubmed
10821863
uniprot
proteins
pubmed
15367664
uniprot
proteins
pubmed
15863505
uniprot
proteins
pubmed
16759287
uniprot
proteins
pubmed
17363903
uniprot
proteins
pubmed
8479922
uniprot
proteins
pubmed
8921394
uniprot
proteins
sequence_length
231
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:10821863, ECO:0000269|PubMed:15367664, ECO:0000269|PubMed:17363903}.
uniprot
proteins