Cdc42ep5
entrez
58804
canonical
uniprot
Q9Z0X0
canonical
ensembl
ENSMUSG00000063838
resolver
ensp
ENSMUSP00000092508
resolver
ensp
ENSMUSP00000345837
resolver
enst
ENSMUST00000076831
resolver
genesymbol
Cdc42ep5
resolver
genesymbol_syn
Borg3
resolver
genesymbol_syn
Cep5
resolver
uniprot
Q3SYK1
resolver
uniprot
Q9QZT9
resolver
uniprot_entry
BORG3_MOUSE
resolver
uniprot_sec
Q3SYK1
resolver
uniprot_sec
Q9QZT9
resolver
amino_acid_sequence
MPVMKQLGPAQPKKRLDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPGAPPVVAPHSVAPPAAPQPPVAVPSPADPLLSFHLDLGPSMLDAVLGVMDAERSETTATKPDGDAHPRVQHPKTRCCSNADLQLDDVIGL
uniprot
proteins
function
FUNCTION: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42. {ECO:0000269|PubMed:10490598, ECO:0000269|PubMed:11035016, ECO:0000269|PubMed:11584266}.
uniprot
proteins
mass_dalton
15545
uniprot
proteins
mutagenesis
MUTAGEN 23..24; /note="IS->AA: No binding with CDC42."; /evidence="ECO:0000269|PubMed:10490598
uniprot
proteins
protein_family
BORG/CEP family
uniprot
proteins
pubmed
10490598
uniprot
proteins
pubmed
11035016
uniprot
proteins
pubmed
11584266
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
150
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endomembrane system {ECO:0000269|PubMed:11035016}; Peripheral membrane protein {ECO:0000269|PubMed:11035016}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11035016}.
uniprot
proteins