Tdrd7
entrez
85425
canonical
uniprot
Q9R1R4
canonical
ensembl
ENSRNOG00000055779
resolver
ensp
ENSRNOP00000068568
resolver
ensp
ENSRNOP00000070639
resolver
enst
ENSRNOT00000090186
resolver
genesymbol
Tdrd7
resolver
genesymbol_syn
Pctaire2bp
resolver
uniprot
A0A8L2R3M8
resolver
uniprot
Q5FVD0
resolver
uniprot_entry
A0A8L2R3M8_RAT
resolver
uniprot_entry
TDRD7_RAT
resolver
uniprot_sec
Q5FVD0
resolver
amino_acid_sequence
MLEADLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVVRIEASRSGEIVCYAVACTETARIAQLVARQRTSKRKTGRQINCQMRVKKTMPFFLEGKPKATLRQPGFASDYSISKKPNPTLLREKGSTLGAKADVDMPPYPDAPVQRHVSMSANSSVTVLRSHPEASKLQFMGYSPKPHCLLLFSPKSSLPAPFQTHISRACPKEVNDNLNQTVEKPNVTPPASYTNKMDEVQNRIKEILDKHNNGIWISKLPHFYKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGGQDLLLYPAKREQPLRSDQDPEKERPPPPPAPRQEVPSKGSPAVMPDVKEKVAELLGKYSSGLWASALPKAFEDMYKVKFPEDALKNLASLSDVCTINYISGNTQKAILYAKLPLPTDKILKDEAQAQGDFDIKSMIEQEYLQIEKNMAESADDFVEDITVPPLVIPTEASPSVLVVELSNTNDVVIRYVGKDYSAAQELMEDEMKEYYSRNPRVTPIQTVHVGQLLAVNAEEDAWLRAQIISTDENKIKVCYVDYGFCENIEKSKAYRLNPRFCSLSFQATKCKLAGLEILNDDPNLVKVVESLTCGKIFAVEILDKSDIPLVVLYDTSGEDDININATCLKAICDRSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDEARGVAYVYLFTPKNFPDPHRSINRQITNADLWKHQKDVFLSAVSAAASSPGNRNASTPAPGSPAESLRKSHPEVLRKSVLDHTSSFSLEELPPPVHLSKSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVERDQVYAAKVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDVFRKLPFQAVTAQLAGVKCSQWSEEASMVFRNHVEKKPLVALVQTVIEHANPWDRKVVVYLVDTSLPDTDTWIHDFMSQYLVELSKAN
uniprot
proteins
function
FUNCTION: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
125310
uniprot
proteins
protein_family
TDRD7 family
uniprot
proteins
pubmed
10727952
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1113
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes to cytoplasmic RNA granules (By similarity). Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity). According to PubMed:10727952 localizes preferentially on the periphery of mitochondria. {ECO:0000250, ECO:0000269|PubMed:10727952}.
uniprot
proteins