Kcnj15
entrez
16516
canonical
uniprot
O88932
canonical
ensembl
ENSMUSG00000062609
resolver
ensp
ENSMUSP00000045218
resolver
ensp
ENSMUSP00000109485
resolver
ensp
ENSMUSP00000109486
resolver
ensp
ENSMUSP00000109487
resolver
ensp
ENSMUSP00000109489
resolver
ensp
ENSMUSP00000109490
resolver
ensp
ENSMUSP00000109492
resolver
ensp
ENSMUSP00000109493
resolver
enst
ENSMUST00000037154
resolver
enst
ENSMUST00000113854
resolver
enst
ENSMUST00000113855
resolver
enst
ENSMUST00000113856
resolver
enst
ENSMUST00000113858
resolver
enst
ENSMUST00000113859
resolver
enst
ENSMUST00000113861
resolver
enst
ENSMUST00000113862
resolver
genesymbol
Kcnj15
resolver
genesymbol_syn
Kir4.2
resolver
uniprot
F8WH12
resolver
uniprot
Q3TNE6
resolver
uniprot
Q53Z04
resolver
uniprot
Q9JK34
resolver
uniprot_entry
F8WH12_MOUSE
resolver
uniprot_entry
KCJ15_MOUSE
resolver
uniprot_entry
Q3TNE6_MOUSE
resolver
uniprot_entry
Q53Z04_MOUSE
resolver
uniprot_sec
Q9JK34
resolver
activity_regulation
ACTIVITY REGULATION: Channel activity is regulated by variations of cytosolic pH; reversibly inhibited by acidic pH values (PubMed:9882736). Inhibited by Ba(2+) and Cs(+) in a voltage-dependent manner (PubMed:9882736). {ECO:0000269|PubMed:9882736}.
uniprot
proteins
amino_acid_sequence
MDAIHLGMSSAPLVKHTNGVGLKAHRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVVYYAIAFIHGDLQLGESNSNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVISKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQKLEEQYRQEDQRERELRSLLLQQSNV
uniprot
proteins
function
FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages (PubMed:9882736). The inward rectification is mainly due to the blockage of outward current by internal magnesium. {ECO:0000269|PubMed:9882736}.
uniprot
proteins
mass_dalton
42605
uniprot
proteins
protein_family
Inward rectifier-type potassium channel (TC 1.A.2.1) family
uniprot
proteins
protein_family
KCNJ15 subfamily
uniprot
proteins
pubmed
10906485
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
33811157
uniprot
proteins
pubmed
9882736
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q91ZF1}.
uniprot
proteins
transmembrane_region
TRANSMEM 61..87; /note="Helical; Name=M1"; /evidence="ECO:0000250|UniProtKB:P49655"; TRANSMEM 140..165; /note="Helical; Name=M2"; /evidence="ECO:0000250|UniProtKB:P49655
uniprot
proteins