Mfge8
entrez
25277
canonical
uniprot
P70490
canonical
ensembl
ENSRNOG00000017510
resolver
ensp
ENSRNOP00000060643
resolver
enst
ENSRNOT00000067889
resolver
genesymbol
Mfge8
resolver
genesymbol_syn
Ags
resolver
uniprot
A0A0G2K506
resolver
uniprot
A0ACM8QA06
resolver
uniprot
F7F6M0
resolver
uniprot
Q1PBJ1
resolver
uniprot_entry
A0ACM8QA06_RAT
resolver
uniprot_entry
MFGM_RAT
resolver
uniprot_entry
Q1PBJ1_RAT
resolver
uniprot_sec
A0A0G2K506
resolver
uniprot_sec
F7F6M0
resolver
amino_acid_sequence
MQFSRVLAALCGVLLCASGLFAASGDFCDSSLCLNGGTCLMGQDNDIYCLCPEGFTGLVCNETEKGPCSPNPCFHDAKCLVTEDTQRGDIFTEYICQCPVGYSGIHCELGCSTKLGLEGGAIADSQISASSVYMGFMGLQRWGPELARLYRTGIVNAWTASSYDSKPWIQVDFLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRRFEFIQDESGTGDKEFMGNQDNNSLKINMFNPTLEAQYIRLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQITASSSYKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQKKVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGTSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPLSWHNRITLRLELLGC
uniprot
proteins
function
FUNCTION: Contributes to phagocytic removal of apoptotic cells in many tissues. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Appears to participate in the O-acetylation of GD3 ganglioside sialic acid. {ECO:0000250}.
uniprot
proteins
mass_dalton
47413
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8780713
uniprot
proteins
sequence_length
427
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:P79385}; Peripheral membrane protein {ECO:0000250|UniProtKB:P79385}. Secreted {ECO:0000250|UniProtKB:P79385}. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:P79385}; Peripheral membrane protein {ECO:0000250|UniProtKB:P79385}. Note=Located in the acrosomal region of zona-pellucida bound sperm. {ECO:0000250|UniProtKB:P79385}.
uniprot
proteins