Cfap100
entrez
243538
canonical
uniprot
Q80VN0
canonical
ensembl
ENSMUSG00000048794
resolver
ensp
ENSMUSP00000059976
resolver
ensp
ENSMUSP00000126515
resolver
ensp
ENSMUSP00000210566
resolver
ensp
ENSMUSP00000210568
resolver
ensp
ENSMUSP00000210571
resolver
enst
ENSMUST00000062750
resolver
enst
ENSMUST00000165673
resolver
genesymbol
Cfap100
resolver
genesymbol_syn
Ccdc37
resolver
uniprot
A0A171EBL0
resolver
uniprot
E9PYA2
resolver
uniprot
Q6AXD6
resolver
uniprot_entry
A0A171EBL0_MOUSE
resolver
uniprot_entry
CP100_MOUSE
resolver
uniprot_sec
E9PYA2
resolver
uniprot_sec
Q6AXD6
resolver
amino_acid_sequence
MAFKARSSRFSVKMVEDTGGSQDLINNSFSSFIEEKSKESKKNKGNVTISDRSSNPFHISRDMDYFLLREQEQNQAIAEREQKKILRVHQKMTYASKVSAKHTSLRRELQLEDEMEQQLLNAEAKEMNCFRENNDWKLAMTRERKREPETLNDYMEKRRSMFLLQYALAMKRNEIQRLEMLATREENRLERAEKFLEKDASLFDEFLRENDRNSVQAMRMAEKETKIKTEKIVEIRELTAQITSIKSEISKFEDTLKHYKIYKEFLYKLSPKEWLDEQQEKHLAFKRAKESSELTRNNSTAILFGDKGSGSKSKTAFLWKEVPGLKKVTKTGRLVKALSSSIQSLPQVGQLTQLSPHSELDSRLSSTMFPSQDDTDSDGEELALYFTEPQQLLDVFTKLEEENLSLIQNTQEMEETLDELNVTLKNTQIRMDKEVNLLKQWIASMMISISKEEESAAELELKARVFHFGEYQGDQQDTMLESLNHKVLEVYRKCVGMQQEANLGTVQMLTVVERQLDELLENLERVPQVKIEQAEKAKERERRMRLREEKAMMQKQLQEERLQRARARAQAKIKKKRGRKLISRSHPPVIKVKEVREQTLINKDKEEMLFFFT
uniprot
proteins
function
FUNCTION: Microtubule-associated protein that promotes microtubule polymerization and regulates microtubule organization (By similarity). Plays a critical role in ensuring proper epidermal development and function by regulating mitosis in keratinocytes (PubMed:40593606). Maintains spindle pole integrity during keratinocyte division through the recruitment of the microtubule glutamylase TTLL13 to spindle poles, thereby enhancing localized microtubule glutamylation (PubMed:40593606). This modification stabilizes spindle microtubules, ensuring accurate spindle assembly, faithful chromosome segregation, and efficient mitotic progression (PubMed:40593606). May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm (By similarity). {ECO:0000250|UniProtKB:A8I4E9, ECO:0000250|UniProtKB:Q494V2}.
uniprot
proteins
mass_dalton
72033
uniprot
proteins
protein_family
CFAP100 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
40593606
uniprot
proteins
sequence_length
613
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A8I4E9}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:40593606}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q494V2}. Note=Localizes to microtubules. {ECO:0000250|UniProtKB:Q494V2}.
uniprot
proteins