HTR3E
entrez
285242
canonical
uniprot
A5X5Y0
canonical
ensembl
ENSG00000186038
resolver
ensp
ENSP00000335511
resolver
ensp
ENSP00000395833
resolver
ensp
ENSP00000401444
resolver
ensp
ENSP00000401900
resolver
ensp
ENSP00000406050
resolver
genesymbol
HTR3E
resolver
hgnc
HGNC:24005
resolver
uniprot
A8IKD7
resolver
uniprot
E9PGF1
resolver
uniprot
Q495G1
resolver
uniprot
Q495G3
resolver
uniprot
Q6V706
resolver
uniprot
Q6V707
resolver
uniprot
Q7Z6B2
resolver
uniprot_entry
5HT3E_HUMAN
resolver
uniprot_sec
A8IKD7
resolver
uniprot_sec
E9PGF1
resolver
uniprot_sec
Q495G1
resolver
uniprot_sec
Q495G3
resolver
uniprot_sec
Q6V706
resolver
uniprot_sec
Q6V707
resolver
uniprot_sec
Q7Z6B2
resolver
amino_acid_sequence
MEGSWFHRKRFSFYLLLGFLLQGRGVTFTINCSGFGQHGADPTALNSVFNRKPFRPVTNISVPTQVNISFAMSAILDVNEQLHLLSSFLWLEMVWDNPFISWNPEECEGITKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKSGNRVPFKITLLLGYNVFLLMMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFITHLLHVATTQPPPLPRWLHSLLLHCNSPGRCCPTAPQKENKGPGLTPTHLPGVKEPEVSAGQMPGPAEAELTGGSEWTRAQREHEAQKQHSVELWLQFSHAMDAMLFRLYLLFMASSIITVICLWNT
uniprot
proteins
function
FUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. {ECO:0000269|PubMed:17392525}.
uniprot
proteins
mass_dalton
51438
uniprot
proteins
protein_family
5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily
uniprot
proteins
protein_family
HTR3E sub-subfamily
uniprot
proteins
protein_family
Ligand-gated ion channel (TC 1.A.9) family
uniprot
proteins
pubmed
12801637
uniprot
proteins
pubmed
14597179
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17392525
uniprot
proteins
pubmed
19012743
uniprot
proteins
sequence_length
456
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic cell membrane {ECO:0000305|PubMed:17392525}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:17392525, ECO:0000269|PubMed:19012743}; Multi-pass membrane protein {ECO:0000255}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. {ECO:0000269|PubMed:17392525}.
uniprot
proteins
transmembrane_region
TRANSMEM 249..269; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 283..303; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 434..454; /note="Helical; Name=4"; /evidence="ECO:0000255
uniprot
proteins