AP1M1
entrez
8907
canonical
uniprot
Q9BXS5
canonical
ensembl
ENSG00000072958
resolver
ensp
ENSP00000291439
resolver
ensp
ENSP00000388996
resolver
genesymbol
AP1M1
resolver
genesymbol_syn
CLTNM
resolver
hgnc
HGNC:13667
resolver
uniprot
B3KNH5
resolver
uniprot
Q4TTY5
resolver
uniprot
Q59EK3
resolver
uniprot_entry
AP1M1_HUMAN
resolver
uniprot_entry
B3KNH5_HUMAN
resolver
uniprot_entry
Q59EK3_HUMAN
resolver
uniprot_sec
Q4TTY5
resolver
amino_acid_sequence
MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ
uniprot
proteins
function
FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
uniprot
proteins
mass_dalton
48587
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. {ECO:0000250}.
uniprot
proteins
protein_family
Adaptor complexes medium subunit family
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
18073204
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
uniprot
proteins