PHYHD1
entrez
254295
canonical
uniprot
Q5SRE7
canonical
ensembl
ENSG00000175287
resolver
ensp
ENSP00000309515
resolver
ensp
ENSP00000361673
resolver
ensp
ENSP00000409928
resolver
genesymbol
PHYHD1
resolver
hgnc
HGNC:23396
resolver
uniprot
A6PWN9
resolver
uniprot
A6PWP0
resolver
uniprot
B3KT57
resolver
uniprot
B4E3X8
resolver
uniprot
Q5SRE9
resolver
uniprot
Q5SRF0
resolver
uniprot
Q7Z623
resolver
uniprot
Q7Z7P9
resolver
uniprot
Q96GM4
resolver
uniprot_entry
PHYD1_HUMAN
resolver
uniprot_sec
A6PWN9
resolver
uniprot_sec
A6PWP0
resolver
uniprot_sec
B3KT57
resolver
uniprot_sec
B4E3X8
resolver
uniprot_sec
Q5SRE9
resolver
uniprot_sec
Q5SRF0
resolver
uniprot_sec
Q7Z623
resolver
uniprot_sec
Q7Z7P9
resolver
uniprot_sec
Q96GM4
resolver
activity_regulation
ACTIVITY REGULATION: Activity is increased by ascorbate. Inhibited by myristoyl-CoA. {ECO:0000269|PubMed:21530488}.
uniprot
proteins
amino_acid_sequence
MACLSPSQLQKFQQDGFLVLEGFLSAEECVAMQQRIGEIVAEMDVPLHCRTEFSTQEEEQLRAQGSTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFKSITHSFKVQTLARSLGLQMPVVVQSMYIFKQPHFGGEVSPHQDASFLYTEPLGRVLGVWIAVEDATLENGCLWFIPGSHTSGVSRRMVRAPVGSAPGTSFLGSEPARDNSLFVPTPVQRGALVLIHGEVVHKSKQNLSDRSRQAYTFHLMEASGTTWSPENWLQPTAELPFPQLYT
uniprot
proteins
ec_number
1.14.11.-
uniprot
proteins
function
FUNCTION: 2-oxoglutarate(2OG)-dependent dioxygenase that catalyzes the conversion of 2-oxoglutarate to succinate and CO(2) in an iron-dependent manner (PubMed:21530488). However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism (PubMed:21530488). Does not show detectable activity towards fatty acid CoA thioesters (PubMed:21530488). {ECO:0000269|PubMed:21530488}.; FUNCTION: [Isoform 2]: Isoform 2 probably lacks enzyme activity. {ECO:0000269|PubMed:21530488}.; FUNCTION: [Isoform 3]: Isoform 3 probably lacks enzyme activity. {ECO:0000269|PubMed:21530488}.
uniprot
proteins
mass_dalton
32411
uniprot
proteins
protein_family
PHYHD1 subfamily
uniprot
proteins
protein_family
PhyH family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
21530488
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
291
uniprot
proteins