CXXC1
entrez
30827
canonical
uniprot
Q9P0U4
canonical
ensembl
ENSG00000154832
resolver
ensp
ENSP00000285106
resolver
ensp
ENSP00000390475
resolver
ensp
ENSP00000553591
resolver
genesymbol
CXXC1
resolver
genesymbol_syn
CFP1
resolver
genesymbol_syn
CGBP
resolver
genesymbol_syn
PCCX1
resolver
genesymbol_syn
PHF18
resolver
hgnc
HGNC:24343
resolver
uniprot
B2RC03
resolver
uniprot
Q8N2W4
resolver
uniprot
Q96BC8
resolver
uniprot
Q9P2V7
resolver
uniprot_entry
CXXC1_HUMAN
resolver
uniprot_sec
B2RC03
resolver
uniprot_sec
Q8N2W4
resolver
uniprot_sec
Q96BC8
resolver
uniprot_sec
Q9P2V7
resolver
amino_acid_sequence
MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
uniprot
proteins
function
FUNCTION: Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. {ECO:0000269|PubMed:21407193}.
uniprot
proteins
mass_dalton
75712
uniprot
proteins
mutagenesis
MUTAGEN 169; /note="C->A: Complete loss of DNA binding activity. No effect on localization in nuclear speckles."; /evidence="ECO:0000269|PubMed:11572867"; MUTAGEN 208; /note="C->A: Complete loss of DNA binding activity. No effect on localization in nuclear speckles."; /evidence="ECO:0000269|PubMed:11572867
uniprot
proteins
post_translational_modification
PTM: May be regulated by proteolysis.
uniprot
proteins
pubmed
10688657
uniprot
proteins
pubmed
10799292
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11572867
uniprot
proteins
pubmed
12200428
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16177791
uniprot
proteins
pubmed
16253997
uniprot
proteins
pubmed
17355966
uniprot
proteins
pubmed
17998332
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18838538
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
21407193
uniprot
proteins
pubmed
23178126
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25218447
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
656
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000269|PubMed:12200428, ECO:0000269|PubMed:17355966}. Nucleus {ECO:0000250|UniProtKB:Q9CWW7}. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
uniprot
proteins