Tdo2
entrez
56720
canonical
uniprot
P48776
canonical
ensembl
ENSMUSG00000028011
resolver
ensp
ENSMUSP00000029645
resolver
enst
ENSMUST00000029645
resolver
genesymbol
Tdo2
resolver
genesymbol_syn
TDO2
resolver
genesymbol_syn
Tdo
resolver
genesymbol_syn
tdo variant1
resolver
uniprot
Q8VCW3
resolver
uniprot_entry
Q8VCW3_MOUSE
resolver
uniprot_entry
T23O_MOUSE
resolver
amino_acid_sequence
MSGCPFAGNSVGYTLKNVSMEDNEEDRAQTGVNRASKGGLIYGNYLQLEKILNAQELQSEVKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVIARMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHYRDNFGGDYNELLLKSEQEQTLLQLVEAWLERTPGLEPNGFNFWGKFEKNILKGLEEEFLRIQAKTDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGTKAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLVPRHWVPKMNPIIHKFLYTAEYSDSSYFSSDESD
uniprot
proteins
ec_number
1.13.11.11
uniprot
proteins
function
FUNCTION: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. {ECO:0000255|HAMAP-Rule:MF_03020}.
uniprot
proteins
mass_dalton
47756
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2. {ECO:0000255|HAMAP-Rule:MF_03020}.
uniprot
proteins
protein_family
3-dioxygenase family
uniprot
proteins
protein_family
Tryptophan 2
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
406
uniprot
proteins