Rmc1
entrez
76482
canonical
uniprot
Q8VC42
canonical
ensembl
ENSMUSG00000024410
resolver
ensp
ENSMUSP00000025276
resolver
enst
ENSMUST00000025276
resolver
genesymbol
Rmc1
resolver
genesymbol_syn
3110002H16Rik
resolver
genesymbol_syn
Mic1
resolver
genesymbol_syn
Wdr98
resolver
uniprot
O35606
resolver
uniprot
Q3TWH4
resolver
uniprot
Q3U4H5
resolver
uniprot
Q3UMX3
resolver
uniprot_entry
Q3TWH4_MOUSE
resolver
uniprot_entry
Q3U4H5_MOUSE
resolver
uniprot_entry
Q3UMX3_MOUSE
resolver
uniprot_entry
RMC1_MOUSE
resolver
uniprot_sec
O35606
resolver
amino_acid_sequence
MGGEDYYLELCERPVQFEKANPVNCVFFDEANKQVFAVRSGGATGVVVKGPDDRNPISFRMDDRGEVKCIKFSLENKILAVQRTAKAVDFCNFIPDNSQLEYTQECKTKNANILGFCWTSSTEIVFITDQGIEFYQVMPEKRSLKLLKSHNINVNWYTYCPESAVILLSTTVLENVLQPFHFRAGTMSKLPKFEIELPAAPKSTKLSLSERDIAMATIYGQLYILFLRHHSRTSNSTGAEVVLYHLPREGACKKMHILKLNRTGKFALNVVDNLVVVHHQDTETSVIFDIRLRGEFDGTVTFHHPVLPARSIQPYEIPLAGPAAVTSQSPVPCKLYSSSWIVFQPDIIISASQGYLWNLQVKLQPIVNLLPDKGRLMDFLLQRKECKAVVLSVCSQMLSESDRATLPVIATVFDKLNHEYKKYLDADQSYTMAVEAGQSRSNPPLKRPVRTQAVVDQSDVYTQVLSPFVENKEMPHKFVIAVLMEYIRSLNQFQIPVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLDMLKRLSTANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAARQTDDVMLFYTIFRFFEQRNQRLRGNPNFTPGEHCEEHVAFFKQVFGEQALMRPTTF
uniprot
proteins
function
FUNCTION: Component of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization. {ECO:0000250|UniProtKB:Q96DM3}.
uniprot
proteins
mass_dalton
74922
uniprot
proteins
protein_family
RMC1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9211850
uniprot
proteins
sequence_length
657
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q96DM3}. Late endosome membrane {ECO:0000250|UniProtKB:Q96DM3}.
uniprot
proteins