GAS2L1
entrez
10634
canonical
uniprot
Q99501
canonical
ensembl
ENSG00000185340
resolver
ensp
ENSP00000383995
resolver
ensp
ENSP00000478343
resolver
ensp
ENSP00000478908
resolver
ensp
ENSP00000479551
resolver
ensp
ENSP00000481012
resolver
ensp
ENSP00000552394
resolver
ensp
ENSP00000552395
resolver
ensp
ENSP00000552397
resolver
ensp
ENSP00000552398
resolver
ensp
ENSP00000552400
resolver
ensp
ENSP00000581563
resolver
ensp
ENSP00000581564
resolver
ensp
ENSP00000581566
resolver
ensp
ENSP00000581568
resolver
enst
ENST00000611648
resolver
enst
ENST00000616432
resolver
enst
ENST00000618518
resolver
enst
ENST00000621062
resolver
enst
ENST00000882335
resolver
enst
ENST00000882336
resolver
enst
ENST00000882338
resolver
enst
ENST00000882339
resolver
enst
ENST00000882341
resolver
enst
ENST00000911504
resolver
enst
ENST00000911505
resolver
enst
ENST00000911507
resolver
enst
ENST00000911509
resolver
genesymbol
GAS2L1
resolver
genesymbol_syn
GAR22
resolver
hgnc
HGNC:16955
resolver
uniprot
A0A024R1C7
resolver
uniprot
A0A087WU34
resolver
uniprot
A0A5E8
resolver
uniprot
B5MCR7
resolver
uniprot
Q53EN7
resolver
uniprot
Q92640
resolver
uniprot
Q9BUY9
resolver
uniprot_entry
A0A087WU34_HUMAN
resolver
uniprot_entry
A0A5E8_HUMAN
resolver
uniprot_entry
GA2L1_HUMAN
resolver
uniprot_sec
A0A024R1C7
resolver
uniprot_sec
B5MCR7
resolver
uniprot_sec
Q53EN7
resolver
uniprot_sec
Q92640
resolver
uniprot_sec
Q9BUY9
resolver
amino_acid_sequence
MADPVAGIAGSAAKSVRPFRSSEAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAARALAAARPARGVAFQAHSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARGPRMTPSDLRNLDELVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLEHYLDKHDPCRCSSTAHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRPEMTPVSLRSTKEGPETPPRPRDQLPPHPRSRRYSGDSDSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPASPRRPPALRSQSRDRLDRGRPRGAPGGRGAQLSVPSPARRARSQSREEQAVLLVRRDRDGQHSWVPRGRGSGGSGRSTPQTPRARSPAAPRLSRVSSPSPELGTTPASIFRTPLQLDPQQEQQLFRRLEEEFLANARALEAVASVTPTGPVPDPARAPDPPAPDSAYCSSSSSSSSLSVLGGKCGQPGDSGRTANGLPGPRSQALSSSSDEGSPCPGMGGPLDAPGSPLACTEPSRTWARGRMDTQPDRKPSRIPTPRGPRRPSGPAELGTWHALHSVTPRAEPDSWM
uniprot
proteins
function
FUNCTION: Involved in the cross-linking of microtubules and microfilaments (PubMed:12584248, PubMed:24706950). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (PubMed:24706950). {ECO:0000269|PubMed:12584248, ECO:0000269|PubMed:24706950}.
uniprot
proteins
mass_dalton
72717
uniprot
proteins
mutagenesis
MUTAGEN 647..648; /note="IP->NN: Loss of microtubule-end localization and microtubule plus-end tracking. Decreases MAPRE1 binding."; /evidence="ECO:0000269|PubMed:24706950
uniprot
proteins
protein_family
GAS2 family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
12584248
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18088087
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24706950
uniprot
proteins
pubmed
8975699
uniprot
proteins
sequence_length
681
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24706950}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:24706950}. Note=Colocalizes with the tips of microtubule plus ends. {ECO:0000269|PubMed:24706950}.
uniprot
proteins