Igbp1
entrez
18518
canonical
uniprot
Q61249
canonical
ensembl
ENSMUSG00000031221
resolver
ensp
ENSMUSP00000033570
resolver
enst
ENSMUST00000033570
resolver
genesymbol
Igbp1
resolver
genesymbol_syn
Pc52
resolver
uniprot_entry
IGBP1_MOUSE
resolver
amino_acid_sequence
MAASEDELLLPRLPELFETSKKLLEDVEVATEPTGSRTIQDKVSKGLELLEKAAGMLSQLDLFSRNEDLEEIASTDLKYLMVPALQGALTMKQVNPSKRLDHLQRAREHFVHFLTQCHCYHVAEFQLPQTKTNSAENNTASSSMAYPNLVAMASQRQAKIERYKQKKEVEHRLSALKSAVESGQADDERVREYHLLHLRRWIAVSLEELESIDQEIKILKEKDSPREETACHSSLPEKPPMKPFILTRNKAQAKVFGTGYPSLATMTVSDWYEQHQKYGVLPDRGIAKPASADFQRAAQQQEDQEQKDEESEEKALHRMREWDDWKDTHPRGYGNRQNMG
uniprot
proteins
function
FUNCTION: Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.
uniprot
proteins
mass_dalton
38971
uniprot
proteins
post_translational_modification
PTM: Phosphorylated.; PTM: Monoubiquitination by MID1 triggers calpain-mediated cleavage and switches IGBP1 activity from protective to destructive. {ECO:0000250}.
uniprot
proteins
protein_family
IGBP1/TAP42 family
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21454489
uniprot
proteins
pubmed
7876543
uniprot
proteins
pubmed
9573385
uniprot
proteins
sequence_length
340
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
uniprot
proteins