F13a1
entrez
60327
canonical
uniprot
O08619
canonical
ensembl
ENSRNOG00000015957
resolver
ensp
ENSRNOP00000021568
resolver
enst
ENSRNOT00000021568
resolver
genesymbol
F13a1
resolver
genesymbol_syn
F13a
resolver
uniprot
G3V811
resolver
uniprot_entry
F13A_RAT
resolver
uniprot_entry
G3V811_RAT
resolver
amino_acid_sequence
MSDTPATTFGGRGAIPPNNSNAAGVDLPTEDLQGLVPRGVSLKDYLNVTAVHLFKERWDSNKIVHHTDKFDNNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVTELQSGKWGAKVIMNEDRSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTQRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDIGGIFHGDFNDIKSRSWSYGQFEDGILDACLFVMDKAEMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNVYAYGIPPSAWTGSVDILLEYRSSETPVRYGQCWVLAGVFNTFLRCLGIPARVITNYSSAHDNDANLQMDIFLEEDGSVSFKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAVKHGHVCFQFDAPFVLGEVNSDLVYITAKKDGTHVVENVDATHIGKLIVTKEIGGDGMQDITDTYKFQEGQEEERLALETALMYGAKKTLNTEGMVKSSSDVDMNFDVENAVLGKDFRVTITFQNNSSNLYTILAYLSGNITFYTGVSKKEFKTESFEVTLDPLSLEKKEVLIRAGEYMSYLLEQGLLHFFVTARINETRVVLAKQKAIVLTIPKVTIKVRGTAMVGSDMVVTVEFTNPLKETLKNVWLHLEGPGVMRPKRKMFREIRPNATVQWEEVCQPWVSGHRKLNASMTSDSLRHVYGELDLQIRRRPTV
uniprot
proteins
ec_number
2.3.2.13
uniprot
proteins
function
FUNCTION: Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. {ECO:0000250|UniProtKB:P00488}.
uniprot
proteins
mass_dalton
82659
uniprot
proteins
post_translational_modification
PTM: The activation peptide is released by thrombin. {ECO:0000250}.
uniprot
proteins
protein_family
Transglutaminase family
uniprot
proteins
protein_family
Transglutaminase superfamily
uniprot
proteins
sequence_length
732
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P00488}. Secreted {ECO:0000250|UniProtKB:P00488}. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma. {ECO:0000250|UniProtKB:P00488}.
uniprot
proteins