Anp32e
entrez
66471
canonical
uniprot
P97822
canonical
ensembl
ENSMUSG00000015749
resolver
ensp
ENSMUSP00000015893
resolver
ensp
ENSMUSP00000128483
resolver
ensp
ENSMUSP00000130599
resolver
genesymbol
Anp32e
resolver
genesymbol_syn
Cpd1
resolver
uniprot
E9Q5H9
resolver
uniprot
Q3TH89
resolver
uniprot
Q3TX26
resolver
uniprot
Q8BPF8
resolver
uniprot
Q8C2L4
resolver
uniprot
Q8C7Q8
resolver
uniprot
Q9CZD2
resolver
uniprot_entry
AN32E_MOUSE
resolver
uniprot_sec
E9Q5H9
resolver
uniprot_sec
Q3TH89
resolver
uniprot_sec
Q3TX26
resolver
uniprot_sec
Q8BPF8
resolver
uniprot_sec
Q8C2L4
resolver
uniprot_sec
Q8C7Q8
resolver
uniprot_sec
Q9CZD2
resolver
amino_acid_sequence
MEMKKKINMELKNRAPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDDDEDGDEDEEDEDEDEAGPPEGYEEEEDDDEDEAGSEVGEGEEEVGLSYLMKDEIQDEEDDDDYVDEGEEEEEEEEEGLRGEKRKRDAEDDGEEDDD
uniprot
proteins
function
FUNCTION: Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis. {ECO:0000269|PubMed:11430900, ECO:0000269|PubMed:14964690, ECO:0000269|PubMed:16420440, ECO:0000269|PubMed:24463511}.
uniprot
proteins
mass_dalton
29622
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. The phosphorylation is nuclear localization signal (NLS)-dependent (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
ANP32 family
uniprot
proteins
pubmed
10692581
uniprot
proteins
pubmed
11430900
uniprot
proteins
pubmed
14964690
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15895553
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16420440
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20844742
uniprot
proteins
pubmed
21049064
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23675506
uniprot
proteins
pubmed
24463511
uniprot
proteins
sequence_length
260
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
uniprot
proteins