TMCC2
entrez
9911
canonical
uniprot
O75069
canonical
ensembl
ENSG00000133069
resolver
ensp
ENSP00000329436
resolver
ensp
ENSP00000331842
resolver
ensp
ENSP00000350718
resolver
ensp
ENSP00000437943
resolver
ensp
ENSP00000490308
resolver
ensp
ENSP00000797127
resolver
enst
ENST00000330675
resolver
genesymbol
TMCC2
resolver
genesymbol_syn
KIAA0481
resolver
hgnc
HGNC:24239
resolver
uniprot
A0A0C4DFR1
resolver
uniprot
A2RRH3
resolver
uniprot
B2RAX5
resolver
uniprot
B3KTM7
resolver
uniprot
B7Z1P7
resolver
uniprot
Q6ZN09
resolver
uniprot
Q7Z6C6
resolver
uniprot
Q8IW47
resolver
uniprot_entry
A0A0C4DFR1_HUMAN
resolver
uniprot_entry
Q8IW47_HUMAN
resolver
uniprot_entry
TMCC2_HUMAN
resolver
uniprot_sec
A2RRH3
resolver
uniprot_sec
B2RAX5
resolver
uniprot_sec
B3KTM7
resolver
uniprot_sec
B7Z1P7
resolver
uniprot_sec
Q6ZN09
resolver
uniprot_sec
Q7Z6C6
resolver
amino_acid_sequence
MKRCRSDELQQQQGEEDGAGLEDAASHLPGADLRPGETTGANSAGGPTSDAGAAAAPNPGPRSKPPDLKKIQQLSEGSMFGHGLKHLFHSRRRSREREHQTSQDSQQHQQQQGMSDHDSPDEKERSPEMHRVSYAMSLHDLPARPTAFNRVLQQIRSRPSIKRGASLHSSSGGGSSGSSSRRTKSSSLEPQRGSPHLLRKAPQDSSLAAILHQHQCRPRSSSTTDTALLLADGSNVYLLAEEAEGIGDKVDKGDLVALSLPAGHGDTDGPISLDVPDGAPDPQRTKAAIDHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQQVSRIKQVFEKKNQKSAQTIAQLHKKLEHYRRRLKEIEQNGPSRQPKDVLRDMQQGLKDVGANVRAGISGFGGGVVEGVKGSLSGLSQATHTAVVSKPREFASLIRNKFGSADNIAHLKDPLEDGPPEEAARALSGSATLVSSPKYGSDDECSSASASSAGAGSNSGAGPGGALGSPKSNALYGAPGNLDALLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQEERYRYERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLELQQQQQQVVQLEGVENANARALLGKFINVILALMAVLLVFVSTIANFITPLMKTRLRITSTTLLVLVLFLLWKHWDSLTYLLEHVLLPS
uniprot
proteins
function
FUNCTION: May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE. {ECO:0000269|PubMed:21593558}.
uniprot
proteins
mass_dalton
77449
uniprot
proteins
protein_family
TEX28 family
uniprot
proteins
pubmed
12168954
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21593558
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24454821
uniprot
proteins
pubmed
30220460
uniprot
proteins
pubmed
9455484
uniprot
proteins
sequence_length
709
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21593558, ECO:0000269|PubMed:24454821, ECO:0000269|PubMed:30220460}; Multi-pass membrane protein {ECO:0000255}. Note=Concentrates in discrete patches along peripheral endoplasmic reticulum tubules. {ECO:0000269|PubMed:30220460}.
uniprot
proteins
transmembrane_region
TRANSMEM 649..669; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 682..702; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins