TMBIM4
entrez
51643
canonical
uniprot
Q9HC24
canonical
ensembl
ENSG00000155957
resolver
ensp
ENSP00000286424
resolver
ensp
ENSP00000350965
resolver
ensp
ENSP00000441291
resolver
ensp
ENSP00000488909
resolver
enst
ENST00000286424
resolver
enst
ENST00000358230
resolver
enst
ENST00000542724
resolver
enst
ENST00000633367
resolver
genesymbol
TMBIM4
resolver
genesymbol_syn
GAAP
resolver
genesymbol_syn
LFG4
resolver
hgnc
HGNC:24257
resolver
uniprot
A0A0J9YXA5
resolver
uniprot
A0A0J9YYL9
resolver
uniprot
G3V1M2
resolver
uniprot
G3XAA5
resolver
uniprot
Q542Z6
resolver
uniprot
Q7Z782
resolver
uniprot
Q9UHY5
resolver
uniprot
Q9Y3C2
resolver
uniprot_entry
A0A0J9YYL9_HUMAN
resolver
uniprot_entry
G3V1M2_HUMAN
resolver
uniprot_entry
G3XAA5_HUMAN
resolver
uniprot_entry
LFG4_HUMAN
resolver
uniprot_entry
Q7Z782_HUMAN
resolver
uniprot_sec
A0A0J9YXA5
resolver
uniprot_sec
Q542Z6
resolver
uniprot_sec
Q9UHY5
resolver
uniprot_sec
Q9Y3C2
resolver
amino_acid_sequence
MADPDPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLGLIFALILNRHKYPLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLMHKLSPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
uniprot
proteins
function
FUNCTION: Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release. {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:19553469}.
uniprot
proteins
mass_dalton
26971
uniprot
proteins
protein_family
BI1 family
uniprot
proteins
protein_family
LFG subfamily
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
10931946
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
17319741
uniprot
proteins
pubmed
19553469
uniprot
proteins
pubmed
19784873
uniprot
proteins
pubmed
22418439
uniprot
proteins
sequence_length
238
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:22418439}; Multi-pass membrane protein {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:22418439}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 69..89; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 121..141; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 152..172; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 176..196; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins