Eipr1
entrez
380752
canonical
uniprot
Q8K0G5
canonical
ensembl
ENSMUSG00000036613
resolver
ensp
ENSMUSP00000152220
resolver
ensp
ENSMUSP00000312542
resolver
enst
ENSMUST00000221877
resolver
genesymbol
Eipr1
resolver
genesymbol_syn
Tssc1
resolver
uniprot
E9QN80
resolver
uniprot_entry
EIPR1_MOUSE
resolver
uniprot_sec
E9QN80
resolver
amino_acid_sequence
MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADKGVLATCYNKTTDSRVQACAAVWRMPKELESGSHESPDDPASTAQTLELLCHLDNSAQGNVACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDGDISDPEEHHAEKSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHILL
uniprot
proteins
function
FUNCTION: Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network (By similarity). Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein (By similarity). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex (By similarity). Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles (By similarity). Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes (By similarity). {ECO:0000250|UniProtKB:Q53HC9, ECO:0000250|UniProtKB:Q5PPK9}.
uniprot
proteins
mass_dalton
43127
uniprot
proteins
protein_family
WD repeat EIPR1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
386
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q53HC9}.
uniprot
proteins