Inhibition of host MAVS by virus
uniprot_keyword
KW-1097
canonical
name
Inhibition of host MAVS by virus
uniprot
definition
Viral protein involved in the evasion of host innate defense by inhibiting the MAVS protein. During viral replication, dsRNA is produced and detected by DDX58/RIG-I or IFIH1/MDA5 that will activate MAVS to coordinate pathways leading to induction of antiviral cytokines. Several viral proteins including NS3/4A from Hepatitis C, or protease 3C from hepatitis A virus, cleave MAVS to abrogate its activity.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords