Plin1
entrez
103968
canonical
uniprot
Q8CGN5
canonical
ensembl
ENSMUSG00000030546
resolver
ensp
ENSMUSP00000032762
resolver
ensp
ENSMUSP00000146028
resolver
genesymbol
Plin1
resolver
genesymbol_syn
Peri
resolver
genesymbol_syn
Plin
resolver
uniprot
Q4V9U2
resolver
uniprot
Q8C0F5
resolver
uniprot_entry
PLIN1_MOUSE
resolver
uniprot_sec
Q4V9U2
resolver
uniprot_sec
Q8C0F5
resolver
amino_acid_sequence
MSMNKGPTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGASNLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNSISVPIASTSDKVLGATLAGCELALGMAKETAEYAANTRVGRLASGGADLALGSIEKVVEFLLPPDKESAPSSGRQRTQKAPKAKPSLVRRVSTLANTLSRHTMQTTAWALKQGHSLAMWIPGVAPLSSLAQWGASAAMQVVSRRQSEVRVPWLHNLAASQDESHDDQTDTEGEETDDEEEEEESEAEENVLREVTALPNPRGLLGGVVHTVQNTLRNTISAVTWAPAAVLGTVGRILHLTPAQAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPSAEAERKGSGARPASPESTPRPGQPRGSLRSVRGLSAPSCPGLDDKTEASARPGFLAMPREKPARRVSDSFFRPSVMEPILGRAQYSQLRKKS
uniprot
proteins
function
FUNCTION: Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness (By similarity). Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. {ECO:0000250, ECO:0000269|PubMed:23481402}.
uniprot
proteins
mass_dalton
55596
uniprot
proteins
post_translational_modification
PTM: Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Perilipin family
uniprot
proteins
pubmed
11641724
uniprot
proteins
pubmed
15292255
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19921680
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23481402
uniprot
proteins
pubmed
24945349
uniprot
proteins
sequence_length
517
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000250|UniProtKB:O60240}. Lipid droplet {ECO:0000269|PubMed:23481402, ECO:0000269|PubMed:24945349}. Note=Lipid droplet surface-associated. {ECO:0000250|UniProtKB:O60240}.
uniprot
proteins