Gdnf
entrez
14573
canonical
uniprot
P48540
canonical
ensembl
ENSMUSG00000022144
resolver
ensp
ENSMUSP00000022744
resolver
genesymbol
Gdnf
resolver
uniprot
O09058
resolver
uniprot
P70446
resolver
uniprot
P97919
resolver
uniprot
P97920
resolver
uniprot
Q6LEL9
resolver
uniprot_entry
GDNF_MOUSE
resolver
uniprot_sec
O09058
resolver
uniprot_sec
P70446
resolver
uniprot_sec
P97919
resolver
uniprot_sec
P97920
resolver
uniprot_sec
Q6LEL9
resolver
amino_acid_sequence
MKLWDVVAVCLVLLHTASAFPLPAGKRLLEAPAEDHSLGHRRVPFALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCESAETMYDKILKNLSRSRRLTSDKVGQACCRPVAFDDDLSFLDDNLVYHILRKHSAKRCGCI
uniprot
proteins
function
FUNCTION: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest. {ECO:0000250|UniProtKB:P39905}.
uniprot
proteins
mass_dalton
23662
uniprot
proteins
protein_family
GDNF subfamily
uniprot
proteins
protein_family
TGF-beta family
uniprot
proteins
pubmed
12168040
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21994944
uniprot
proteins
pubmed
7650763
uniprot
proteins
pubmed
8808409
uniprot
proteins
pubmed
9426245
uniprot
proteins
sequence_length
211
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P39905}.
uniprot
proteins