SYN2
entrez
6854
canonical
uniprot
Q92777
canonical
ensembl
ENSG00000157152
resolver
ensp
ENSP00000480050
resolver
ensp
ENSP00000484916
resolver
genesymbol
SYN2
resolver
hgnc
HGNC:11495
resolver
uniprot
A0A087WW96
resolver
uniprot
A0A087X2E3
resolver
uniprot
A8MY98
resolver
uniprot
B3KRB3
resolver
uniprot
Q59GM1
resolver
uniprot
Q86VA8
resolver
uniprot_entry
B3KRB3_HUMAN
resolver
uniprot_entry
Q59GM1_HUMAN
resolver
uniprot_entry
Q86VA8_HUMAN
resolver
uniprot_entry
SYN2_HUMAN
resolver
uniprot_sec
A0A087WW96
resolver
uniprot_sec
A0A087X2E3
resolver
uniprot_sec
A8MY98
resolver
amino_acid_sequence
MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPAPAAARKAKVLLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAIYKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMNQLLSRTPALSPQRPLTTQQPQSGTLKDPDSSKTPPQRPPPQGGPGQPQGMQPPGKVLPPRRLPPGPSLPPSSSSSSSSSSSAPQRPGGPTTHGDAPSSSSSLAEAQPPLAAPPQKPQPHPQLNKSQSLTNAFSFSESSFFRSSANEDEAKAETIRSLRKSFASLFSD
uniprot
proteins
disease_involvement
DISEASE: Schizophrenia (SCZD) [MIM:181500]: A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. {ECO:0000269|PubMed:15449241}. Note=Disease susceptibility may be associated with variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
62996
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Ser-10 dissociates synapsins from synaptic vesicles. Phosphorylation at Ser-425 by MAPK1/ERK2 and/or MAPK3/ERK1 may play a role in noradrenaline secretion by sympathetic neurons (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
Synapsin family
uniprot
proteins
pubmed
10565545
uniprot
proteins
pubmed
15449241
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
23406870
uniprot
proteins
pubmed
8964517
uniprot
proteins
sequence_length
582
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Synapse.
uniprot
proteins