Q8R092
uniprot
Q8R092
canonical
amino_acid_sequence
MASSSNWLSGVNVVLVMAYGSLVFVLLFIFVKRQIMRFAMKSRRGPHVPVGHNAPKDLKEEIDIRLSRVQDIKYEPQLLADDDTRLLQLETQGNQSCYNYLYRMKALDAIRASEIPFHAEGRHPCSLMGKNFRSYLLDLRNTSTPFKGVGKALIDTLLDGYETARYGTGVFGQSEYLRYQEALSELATVVKARIGSSQRQHQSAAKDLTQSPEMSPTTIQVTYLPSSQKSKRPKHFLELKSFKDNYNTLESTL
uniprot
proteins
function
FUNCTION: Required for the formation of endoplasmic reticulum-plasma membrane junctions and functions as an accessory protein for bridge-like lipid transfer protein BLTP1, participating in lipid delivery between endoplasmic reticulum and cell membranes (By similarity). Regulates the phagocytosis of Gram-negative bacteria like L. pneumophila and E. coli, as well as Gram-positive bacteria such as S. aureus (PubMed:31540829). {ECO:0000250|UniProtKB:Q9BWL3, ECO:0000269|PubMed:31540829}.
uniprot
proteins
mass_dalton
28691
uniprot
proteins
protein_family
Lipid transport auxiliary protein 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
31540829
uniprot
proteins
sequence_length
253
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9BWL3}; Single-pass membrane protein {ECO:0000250|UniProtKB:A0A0K3AWP8}. Golgi apparatus {ECO:0000250|UniProtKB:Q9BWL3}. Mitochondrion {ECO:0000250|UniProtKB:Q9BWL3}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9BWL3}; Single-pass membrane protein {ECO:0000250|UniProtKB:A0A0K3AWP8}. Note=Enriched at endoplasmic reticulum-plasma membrane junctions. {ECO:0000250|UniProtKB:Q9BWL3}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..30; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q4W5H0
uniprot
proteins