Pnoc
entrez
25516
canonical
uniprot
Q62923
canonical
ensembl
ENSRNOG00000014231
resolver
ensembl
ENSRNOG00055006648
resolver
ensembl
ENSRNOG00060010866
resolver
ensembl
ENSRNOG00065018612
resolver
ensp
ENSRNOP00000019117
resolver
ensp
ENSRNOP00055008421
resolver
ensp
ENSRNOP00060014338
resolver
ensp
ENSRNOP00065024897
resolver
enst
ENSRNOT00000019117
resolver
enst
ENSRNOT00055010837
resolver
enst
ENSRNOT00060018417
resolver
enst
ENSRNOT00065031257
resolver
genesymbol
Pnoc
resolver
uniprot
Q64162
resolver
uniprot_entry
PNOC_RAT
resolver
uniprot_sec
Q64162
resolver
amino_acid_sequence
MKILFCDVLLLSLLSSVFSSCPEDCLTCQERLHPAPGSFNLKLCILQCEEKVFPRPLWTLCTKAMASDSEQLSPADPELTSAALYQSKASEMQHLKRMPRVRSVVQARDAEPEADAEPVADEADEVEQKQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGNV
uniprot
proteins
function
FUNCTION: [Nociceptin]: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. {ECO:0000269|PubMed:7566152}.; FUNCTION: [Nocistatin]: Blocks nociceptin action in pain transmission by inhibiting nociceptin-induced hyperalgesia and allodynia. {ECO:0000250|UniProtKB:O62647}.; FUNCTION: [Orphanin FQ2]: Has potent analgesic activity. {ECO:0000250|UniProtKB:Q64387}.
uniprot
proteins
mass_dalton
20479
uniprot
proteins
post_translational_modification
PTM: Specific enzymatic cleavages at paired basic residues probably yield other active peptides besides nociceptin.; PTM: The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.
uniprot
proteins
protein_family
Opioid neuropeptide precursor family
uniprot
proteins
pubmed
7566152
uniprot
proteins
pubmed
8710928
uniprot
proteins
pubmed
8710930
uniprot
proteins
sequence_length
181
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins