G6pc1
entrez
25634
canonical
uniprot
P43428
canonical
ensembl
ENSRNOG00000053448
resolver
ensembl
ENSRNOG00055033526
resolver
ensembl
ENSRNOG00060015588
resolver
ensembl
ENSRNOG00065033341
resolver
ensp
ENSRNOP00000071453
resolver
ensp
ENSRNOP00055047788
resolver
ensp
ENSRNOP00060021381
resolver
ensp
ENSRNOP00065047159
resolver
enst
ENSRNOT00000085831
resolver
enst
ENSRNOT00055057948
resolver
enst
ENSRNOT00060026706
resolver
enst
ENSRNOT00065057318
resolver
genesymbol
G6pc1
resolver
genesymbol_syn
G6pc
resolver
genesymbol_syn
G6pt
resolver
uniprot
Q5FVC9
resolver
uniprot_entry
G6PC1_RAT
resolver
uniprot_sec
Q5FVC9
resolver
amino_acid_sequence
MEERMNVLHDFGIQSTRYLQVNYEDSQDWFVLVSVIADLRNAFYVLFPIWFHIQETVGINLLWVAVVGDWFNLVFKWILFGQRPYWWVLDTDYYSNSSVPLIKQFPVTCETGPGSPSGHAMGTAGVYYVMVTSTLAIFRGKKKSTYGFRCLNVVLWLGYWAVQLNVCLSRIYLAAHFPHQVVAGVLSGIAVAETFSHIRGIYNASLQRYCLITFFLFGFALGFYLLLKGLGVDLLWTLEKAKRWCERPEWVHLDTTPFASLFKNLGTLLGLGLALNSSMYRKSCKGELRKSLPFRLACIVASLGLLHLFDSLKPPSQIESIFYILSFCKSATVPFASVSLIPYCLARLLGQTHKKSL
uniprot
proteins
ec_number
3.1.3.9
uniprot
proteins
function
FUNCTION: Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels. {ECO:0000250|UniProtKB:P35575}.
uniprot
proteins
mass_dalton
40556
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate biosynthesis; gluconeogenesis. {ECO:0000250|UniProtKB:P35575}.
uniprot
proteins
protein_family
Glucose-6-phosphatase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
7860767
uniprot
proteins
pubmed
8198588
uniprot
proteins
pubmed
8865366
uniprot
proteins
sequence_length
357
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P35575}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 29..49; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 61..81; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 118..138; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 148..168; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 171..191; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 212..232; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 255..275; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 292..312; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 321..341; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins