Suclg1
entrez
114597
canonical
uniprot
P13086
canonical
ensembl
ENSRNOG00000005587
resolver
ensp
ENSRNOP00000007624
resolver
genesymbol
Suclg1
resolver
uniprot
Q6P7S4
resolver
uniprot_entry
SUCA_RAT
resolver
uniprot_sec
Q6P7S4
resolver
amino_acid_sequence
MTAAVVAAAATATMVSGSSGLAAARLLSRTFLLQQNGIRHGSYTASRKNIYIDKNTKVICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGKKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHKLTRQGKTRLIGPNCPGIINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTNFIDCLDVFLKDPATEGIVLIGEIGGHAEENAAEFLKEHNSGPKAKPVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISALQSAGVIVSMSPAQLGTCMYKEFEKRKML
uniprot
proteins
ec_number
6.2.1.-
uniprot
proteins
ec_number
6.2.1.4
uniprot
proteins
ec_number
6.2.1.5
uniprot
proteins
ec_number
6.2.1.9
uniprot
proteins
function
FUNCTION: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. Also able to act as an itaconyl- and malyl-CoA synthetase. {ECO:0000255|HAMAP-Rule:MF_03222}.
uniprot
proteins
mass_dalton
36148
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_03222}.
uniprot
proteins
protein_family
Succinate/malate CoA ligase alpha subunit family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
3422742
uniprot
proteins
sequence_length
346
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03222}.
uniprot
proteins