Rilpl2
entrez
80291
canonical
uniprot
Q99LE1
canonical
ensembl
ENSMUSG00000029401
resolver
ensp
ENSMUSP00000031347
resolver
genesymbol
Rilpl2
resolver
uniprot
Q3TB73
resolver
uniprot_entry
RIPL2_MOUSE
resolver
uniprot_sec
Q3TB73
resolver
amino_acid_sequence
MEDHPVREEEDGEEDEGALAKSPLQLTTDDVYDISYVVGRELMALGSDPRVTRLQFKIVRVMEMLETLVNEGSLAVEELRMERDNLKQEVEGLRKAGVSGAQVNLGPDKMVVDLTDPNRPRFTLQELREVLQERNKLKSQLLLVQEELQCYRSGLLPPRETPGGRREKDAVVAMGNGEKEERTIMKKLFSFRSGKHT
uniprot
proteins
function
FUNCTION: Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (PubMed:23264467). May function via activation of RAC1 and PAK1 (By similarity). {ECO:0000250|UniProtKB:Q6AYA0, ECO:0000269|PubMed:23264467}.
uniprot
proteins
mass_dalton
22393
uniprot
proteins
mutagenesis
MUTAGEN 56; /note="F->P: Loss of interaction with MYO5A."; /evidence="ECO:0000269|PubMed:23798443"; MUTAGEN 59; /note="V->Q: Loss of interaction with MYO5A."; /evidence="ECO:0000269|PubMed:23798443"; MUTAGEN 61; /note="V->E: Abolishes homodimerization."; /evidence="ECO:0000269|PubMed:23798443
uniprot
proteins
protein_family
RILPL family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
23264467
uniprot
proteins
pubmed
23798443
uniprot
proteins
pubmed
29125462
uniprot
proteins
sequence_length
197
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23264467}. Cell projection, cilium {ECO:0000269|PubMed:23264467}.
uniprot
proteins