Gar1
entrez
499709
canonical
uniprot
Q6AYA1
canonical
ensembl
ENSRNOG00055027570
resolver
ensembl
ENSRNOG00060002656
resolver
ensembl
ENSRNOG00065014326
resolver
ensp
ENSRNOP00055039299
resolver
ensp
ENSRNOP00060002980
resolver
ensp
ENSRNOP00065018376
resolver
enst
ENSRNOT00055047755
resolver
enst
ENSRNOT00060004245
resolver
enst
ENSRNOT00065023622
resolver
genesymbol
Gar1
resolver
genesymbol_syn
Nola1
resolver
uniprot_entry
GAR1_RAT
resolver
amino_acid_sequence
MSFRGGGRGGFNRGGGGGGFNRGGGSNNHFRGGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGGGGGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGFRGGRGGGGGFRGRGH
uniprot
proteins
function
FUNCTION: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
23011
uniprot
proteins
protein_family
GAR1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
226
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. Nucleus, Cajal body {ECO:0000250}. Note=Also localized to Cajal bodies (coiled bodies). {ECO:0000250}.
uniprot
proteins