Mast3
entrez
546071
canonical
uniprot
Q3U214
canonical
ensembl
ENSMUSG00000031833
resolver
ensp
ENSMUSP00000128703
resolver
ensp
ENSMUSP00000148686
resolver
ensp
ENSMUSP00000271450
resolver
enst
ENSMUST00000166004
resolver
enst
ENSMUST00000211948
resolver
genesymbol
Mast3
resolver
genesymbol_syn
Kiaa0561
resolver
uniprot
A0A1D5RM97
resolver
uniprot
E9QQ28
resolver
uniprot
Q6A047
resolver
uniprot_entry
A0A1D5RM97_MOUSE
resolver
uniprot_entry
MAST3_MOUSE
resolver
uniprot_sec
E9QQ28
resolver
uniprot_sec
Q6A047
resolver
activity_regulation
ACTIVITY REGULATION: Kinase activity with ARPP19 as substrate is down-regulated by PKA-mediated phosphorylation. {ECO:0000250|UniProtKB:O60307}.
uniprot
proteins
amino_acid_sequence
MKSRREKLLIPALTLDLSPSSQSPCLLSPGSPCSPCSPSLGLQPWSCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGNSPLDSPRNFSAAAAISFPFARRADGRRWSLASLPSSGYGTNTPSSTVSSSSSSRERLHQLPFQPTADELRFLSKHFRSSESVVDEDGGRSPRLRPRSRSLSPGRTSGTFDNEIVMMNHVYRERFPKATAQMEGRLQDFLAAFAPGDRLALADGVLGFIHHQIVELARDCLAKSGEALVTSRYFLEMQDKLERLLQDAHERSDSAEVGFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGQAREDQGVKTDLPRYIIRQLGLAKDPLEEIQPLNDLDESQPPAPGSPESRGLGGPSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFVDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPLDAQDLITRLLRQSPMDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFAERSFSEDREDGWGQSLGDRGRRLSADLRLRSWTPASSCQPSSCQTDRGPSPSLLSTISLDVMPKFAFSSEDEGASSGPADPQKPVFILGEPDPPPPTTPVTPKPCNLSADTAVLSHARLRSNSTGARHSTPRPLDAGRGRRLGGSRDPGPEKPRASPGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEEGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKRISKPSSVLHTSRSFSSGLQHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDAPTDTASPPNVSPSSSSPASPATGHTRPSSLHGLAAKLGPPRHKSGRRKSTSSIPPSPLACPPVPTPPPRSPSPLPGHIPIPARSPRLRRGQSADKLGLGTSERLDGDGGRRARGAEAELVVMRRLHLSERRDSFKKQEAVQEVSFDEEPGPPRGVPKIAVQGAEATPGTPGHARKD
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Serine/threonine kinase that phosphorylates ARPP19 at 'Ser-62', resulting in protein phosphatase 2A (PP2A) inhibition by ARPP19. {ECO:0000250|UniProtKB:O60307}.
uniprot
proteins
mass_dalton
144174
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PKA; phosphorylation down-regulates kinase activity. {ECO:0000250|UniProtKB:O60307}.
uniprot
proteins
protein_family
AGC Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
34185323
uniprot
proteins
sequence_length
1321
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:34185323}.
uniprot
proteins