Iqcj-Schip1
entrez
100505386
canonical
uniprot
A0A088MLT8
canonical
ensembl
ENSMUSG00000102422
resolver
ensp
ENSMUSP00000138212
resolver
genesymbol
Iqcj-Schip1
resolver
genesymbol_syn
Iqschfp
resolver
genesymbol_syn
Schip1
resolver
uniprot
A8IJC6
resolver
uniprot
A8IJD0
resolver
uniprot
A8IJD3
resolver
uniprot
F6YL02
resolver
uniprot
F8WI70
resolver
uniprot
Q3TI53
resolver
uniprot
Q52KH1
resolver
uniprot
Q6P9Y8
resolver
uniprot
Q9CX07
resolver
uniprot
Q9JLR0
resolver
uniprot_entry
IQIP1_MOUSE
resolver
uniprot_sec
A8IJC6
resolver
uniprot_sec
A8IJD0
resolver
uniprot_sec
A8IJD3
resolver
uniprot_sec
F6YL02
resolver
uniprot_sec
F8WI70
resolver
uniprot_sec
Q3TI53
resolver
uniprot_sec
Q52KH1
resolver
uniprot_sec
Q6P9Y8
resolver
uniprot_sec
Q9CX07
resolver
uniprot_sec
Q9JLR0
resolver
amino_acid_sequence
MRLEELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLSSSVSMNTFSDSSTPDYREDGMDLGSDAGSSSSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGEEEEEEDDRGYRDDGCPAREPGDVSARIGSSGSGSRSAATTMPSPMPNGNLHPHDPQDLRHNGNVVVAGRPNASRVPRRPIQKTQPPGSRRGGRNRASGGLCLQPPDGGTRVPEEPPAPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSARLQSGMNLQICFVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLMKRSLKPTDLRDMTIGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHMAEKMPAK
uniprot
proteins
function
FUNCTION: May play a role in action potential conduction in myelinated cells through the organization of molecular complexes at nodes of Ranvier and axon initial segments (PubMed:25950943, PubMed:25953347, PubMed:27979964). May also play a role in axon outgrowth and guidance (PubMed:25953347). {ECO:0000269|PubMed:25950943, ECO:0000269|PubMed:25953347, ECO:0000269|PubMed:27979964}.
uniprot
proteins
mass_dalton
61917
uniprot
proteins
mutagenesis
MUTAGEN 53..54; /note="IQ->AA: Loss of interaction with calmodulin."; /evidence="ECO:0000269|PubMed:18550753
uniprot
proteins
pubmed
18550753
uniprot
proteins
pubmed
25950943
uniprot
proteins
pubmed
25953347
uniprot
proteins
pubmed
27979964
uniprot
proteins
sequence_length
559
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, axon {ECO:0000269|PubMed:18550753}. Cytoplasm {ECO:0000250|UniProtKB:B3KU38}. Note=Localizes to the axon initial segments (AIS) and nodes of Ranvier of neurons and is absent from dendrites. {ECO:0000269|PubMed:18550753}.
uniprot
proteins