AIG1
entrez
51390
canonical
uniprot
Q9NVV5
canonical
ensembl
ENSG00000146416
resolver
ensp
ENSP00000275235
resolver
ensp
ENSP00000350509
resolver
ensp
ENSP00000356568
resolver
ensp
ENSP00000356573
resolver
ensp
ENSP00000407817
resolver
ensp
ENSP00000473952
resolver
ensp
ENSP00000485875
resolver
ensp
ENSP00000493676
resolver
ensp
ENSP00000781163
resolver
ensp
ENSP00000786706
resolver
ensp
ENSP00000786708
resolver
ensp
ENSP00000786711
resolver
ensp
ENSP00000786712
resolver
ensp
ENSP00000786714
resolver
ensp
ENSP00000794558
resolver
enst
ENST00000367596
resolver
enst
ENST00000646199
resolver
genesymbol
AIG1
resolver
hgnc
HGNC:21607
resolver
uniprot
A0A2R8YCJ8
resolver
uniprot
B4DPX2
resolver
uniprot
C9J569
resolver
uniprot
Q5T2H2
resolver
uniprot
Q5THU2
resolver
uniprot
Q6N047
resolver
uniprot
Q7Z378
resolver
uniprot
Q8TB14
resolver
uniprot
Q9Y3A9
resolver
uniprot
Q9Y5B4
resolver
uniprot_entry
A0A2R8YCJ8_HUMAN
resolver
uniprot_entry
AIG1_HUMAN
resolver
uniprot_entry
Q5THU2_HUMAN
resolver
uniprot_sec
B4DPX2
resolver
uniprot_sec
C9J569
resolver
uniprot_sec
Q5T2H2
resolver
uniprot_sec
Q6N047
resolver
uniprot_sec
Q7Z378
resolver
uniprot_sec
Q8TB14
resolver
uniprot_sec
Q9Y3A9
resolver
uniprot_sec
Q9Y5B4
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by N-hydroxyhydantoin carbamate JJH260 and beta-lactone KC01. {ECO:0000269|PubMed:27018888}.
uniprot
proteins
amino_acid_sequence
MALVPCQVLRMAILLSYCSILCNYKAIEMPSHQTYGGSWKFLTFIDLVIQAVFFGICVLTDLSSLLTRGSGNQEQERQLKKLISLRDWMLAVLAFPVGVFVVAVFWIIYAYDREMIYPKLLDNFIPGWLNHGMHTTVLPFILIEMRTSHHQYPSRSSGLTAICTFSVGYILWVCWVHHVTGMWVYPFLEHIGPGARIIFFGSTTILMNFLYLLGEVLNNYIWDTQKSMEEEKEKPKLE
uniprot
proteins
ec_number
3.1.-.-
uniprot
proteins
function
FUNCTION: Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (PubMed:27018888). Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids (PubMed:27018888). {ECO:0000269|PubMed:27018888}.
uniprot
proteins
mass_dalton
27458
uniprot
proteins
mutagenesis
MUTAGEN 43; /note="T->A: Loss of hydrolase activity."; /evidence="ECO:0000269|PubMed:27018888"; MUTAGEN 134; /note="H->A: Loss of hydrolase activity."; /evidence="ECO:0000269|PubMed:27018888
uniprot
proteins
protein_family
AIG1 family
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
11266118
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
27018888
uniprot
proteins
sequence_length
238
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:27018888}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 13..30; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 45..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 88..110; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 125..144; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 157..179; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 194..216; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins