Sytl4
entrez
140594
canonical
uniprot
Q8VHQ7
canonical
ensembl
ENSRNOG00000003526
resolver
ensp
ENSRNOP00000004921
resolver
ensp
ENSRNOP00000078420
resolver
enst
ENSRNOT00000004921
resolver
enst
ENSRNOT00000113853
resolver
genesymbol
Sytl4
resolver
uniprot
A0A8I5ZMC6
resolver
uniprot
D3ZTZ2
resolver
uniprot
Q8VHQ6
resolver
uniprot_entry
A0A8I5ZMC6_RAT
resolver
uniprot_entry
D3ZTZ2_RAT
resolver
uniprot_entry
SYTL4_RAT
resolver
uniprot_sec
Q8VHQ6
resolver
amino_acid_sequence
MSEILDLSFLSEMERDLILSVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQEGLGRLISKSNTCVGCNHLVCRECRVLESNGSWRCKVCSKEIELKKATGDWFYDQKVNRFAYRTGSDIIRMSLRRKPAVNKRETVGQSLLQQTQMGDIWPGRRIIQEQQKEQSVLFEVPKLKSGKSALEAESESLDSYTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKEIAPGNQNAVCGDEGDMIFKKNTRKVLRPSEYTKSVIDLRPEDVAQESGILGDRSKSVPGLSVDMEDEEEEEEDIDHLVKLHRQKLARGSMQSGSSMSTIGSMMSLYSEAGDFGNVSVTGKIAFSLKFEQKTQTLVIHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGRFGRNTFLGEAEVHMDSWKLDKKLDHCLPLHGKISTESSPGLPAHKGELVVSLKYIPASKLPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKSGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISSGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMVKQKLGV
uniprot
proteins
function
FUNCTION: Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
75900
uniprot
proteins
mutagenesis
MUTAGEN 21; /note="V->A: Strongly reduces interaction with RAB3A and modulation of exocytosis."; /evidence="ECO:0000269|PubMed:12058058"; MUTAGEN 43; /note="L->A: Strongly reduces interaction with RAB3A and modulation of exocytosis."; /evidence="ECO:0000269|PubMed:12058058
uniprot
proteins
pubmed
12058058
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
672
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:12058058}; Peripheral membrane protein {ECO:0000269|PubMed:12058058}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:12058058}; Peripheral membrane protein {ECO:0000269|PubMed:12058058}. Note=Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles.
uniprot
proteins