Tm2d3
entrez
68634
canonical
uniprot
Q8BJ83
canonical
ensembl
ENSMUSG00000078681
resolver
ensp
ENSMUSP00000032726
resolver
ensp
ENSMUSP00000103119
resolver
ensp
ENSMUSP00000145534
resolver
ensp
ENSMUSP00000259139
resolver
enst
ENSMUST00000206517
resolver
genesymbol
Tm2d3
resolver
uniprot
A0A0U1RNE7
resolver
uniprot
Q9D156
resolver
uniprot_entry
A0A0U1RNE7_MOUSE
resolver
uniprot_entry
TM2D3_MOUSE
resolver
uniprot_sec
Q9D156
resolver
amino_acid_sequence
MEAAAEPLRSVRHLSRVLLFLSQCYILSGDGSLNLEHSQPLAQAIKDPGPTRTFSVVPRAAENQLFSHLTESTEIPPYMTKCPSNGLCSRLPADCIECATNVSCTYGKPVTFDCTVKPSVTCVDQDLKPQRNFVINMTCRFCWQLPETDYECSNSTTCMTVACPRQRYFANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI
uniprot
proteins
function
FUNCTION: Positive regulator of Notch signaling, required for activation of NOTCH1 intracellular processing and NOTCH1 localization to the cell membrane. {ECO:0000269|PubMed:38016980}.
uniprot
proteins
mass_dalton
28880
uniprot
proteins
protein_family
TM2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
38016980
uniprot
proteins
sequence_length
261
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9BRN9}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q9BRN9}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9BRN9}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins