Q86SQ3
uniprot
Q86SQ3
canonical
amino_acid_sequence
MGSRFLLVLLSGASCPPCPKYASCHNSTHCTCEDGFRARSGRTYFHDSSEKCEDINECETGLAKCKYKAYCRNKVGGYICSCLVKYTLFNFLAGIIDYDHPDCYENNSQGTTQSNVDIWVSGVKPGFGKQLPGDKRTKHICVYWEGSEGGWSTEGCSHVHSNGSYTKCKCFHLSSFAVLVALAPKEDPVLTVITQVGLTISLLCLFLAILTFLLCRPIQNTSTSLHLELSLCLFLAHLLFLTGINRTEPEVLCSIIAGLLHFLYLACFTWMLLEGLHLFLTVRNLKVANYTSTGRFKKRFMYPVGYGIPAVIIAVSAIVGPQNYGTFTCWLKLDKGFIWSFMGPVAVIILINLVFYFQVLWILRSKLSSLNKEVSTIQDTRVMTFKAISQLFILGCSWGLGFFMVEEVGKTIGSIIAYSFTIINTLQGVLLFVVHCLLNRQVRLIILSVISLVPKSN
uniprot
proteins
function
FUNCTION: May mediate the cellular interaction between myeloid cells and B-cells. {ECO:0000250|UniProtKB:Q91ZE5}.
uniprot
proteins
mass_dalton
50903
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250|UniProtKB:Q91ZE5}.; PTM: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. {ECO:0000250|UniProtKB:Q91ZE5}.
uniprot
proteins
protein_family
Adhesion G protein-coupled receptor (ADGR) subfamily
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
12565841
uniprot
proteins
pubmed
12679517
uniprot
proteins
pubmed
12731063
uniprot
proteins
pubmed
16753812
uniprot
proteins
pubmed
25713288
uniprot
proteins
sequence_length
457
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000250|UniProtKB:Q91ZE5}; Multi-pass membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 192..212; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 224..244; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 251..271; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 300..320; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 337..357; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 385..405; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 414..434; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins