Rassf7
entrez
66985
canonical
uniprot
Q9DD19
canonical
ensembl
ENSMUSG00000038618
resolver
ensp
ENSMUSP00000038444
resolver
ensp
ENSMUSP00000325702
resolver
enst
ENSMUST00000046890
resolver
genesymbol
Rassf7
resolver
uniprot_entry
RASF7_MOUSE
resolver
amino_acid_sequence
MVLELVAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFANDVQFVLRRTGPSLSGRPSSDNCPPPERCPVRASLPPKPSAIPGREPRKALTFNLRCPKLVPSPSIPEPAALVGPIPDGFADLQDLELRIQRNTEELGHEAFWEQELQREQAREREGQARLQALSAATAEHAARLEALDAQACALEAELRLAAEAPGPPSATASAAERLRQDLATQERHSLEMQGTLALVSQALEAAEHALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPPQLDRTIPSTQDLLSPNRGELQGVPQSHILVSSLSPEVPPMRQSSWR
uniprot
proteins
function
FUNCTION: Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
39247
uniprot
proteins
post_translational_modification
PTM: Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Colocalizes with gamma-tubulin. {ECO:0000250}.
uniprot
proteins