SNX16
entrez
64089
canonical
uniprot
P57768
canonical
ensembl
ENSG00000104497
resolver
ensp
ENSP00000322631
resolver
ensp
ENSP00000322652
resolver
ensp
ENSP00000379621
resolver
ensp
ENSP00000526612
resolver
genesymbol
SNX16
resolver
hgnc
HGNC:14980
resolver
uniprot
A8K4D8
resolver
uniprot
Q658L0
resolver
uniprot
Q8N4U3
resolver
uniprot_entry
SNX16_HUMAN
resolver
uniprot_sec
A8K4D8
resolver
uniprot_sec
Q658L0
resolver
uniprot_sec
Q8N4U3
resolver
amino_acid_sequence
MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQMDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSALEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED
uniprot
proteins
function
FUNCTION: May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. {ECO:0000269|PubMed:12813048, ECO:0000269|PubMed:15951806}.
uniprot
proteins
mass_dalton
39167
uniprot
proteins
mutagenesis
MUTAGEN 144; /note="R->A: Abolishes binding to membranes enriched in phosphatidylinositol 3-phosphate."; /evidence="ECO:0000269|PubMed:15951806"; MUTAGEN 145; /note="Y->A: Abolishes binding to phosphatidylinositol 3-phosphate."; /evidence="ECO:0000269|PubMed:12813048
uniprot
proteins
protein_family
Sorting nexin family
uniprot
proteins
pubmed
12813048
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15951806
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
344
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm {ECO:0000250}. Lysosome {ECO:0000250}.
uniprot
proteins