CEP20
entrez
123811
canonical
uniprot
Q96NB1
canonical
ensembl
ENSG00000133393
resolver
ensembl
ENSG00000276914
resolver
ensp
ENSP00000255759
resolver
ensp
ENSP00000459429
resolver
ensp
ENSP00000459804
resolver
ensp
ENSP00000460312
resolver
ensp
ENSP00000461548
resolver
ensp
ENSP00000461830
resolver
ensp
ENSP00000488051
resolver
ensp
ENSP00000488284
resolver
ensp
ENSP00000488499
resolver
ensp
ENSP00000488552
resolver
enst
ENST00000573396
resolver
enst
ENST00000573429
resolver
enst
ENST00000575073
resolver
enst
ENST00000575744
resolver
enst
ENST00000632623
resolver
enst
ENST00000633304
resolver
enst
ENST00000633985
resolver
enst
ENST00000634146
resolver
genesymbol
CEP20
resolver
genesymbol_syn
C16orf63
resolver
genesymbol_syn
FOPNL
resolver
genesymbol_syn
FOR20
resolver
genesymbol_syn
PHSECRG2
resolver
hgnc
HGNC:26435
resolver
uniprot
B3KPU9
resolver
uniprot
I3L269
resolver
uniprot
I3L2N4
resolver
uniprot
I3L4V2
resolver
uniprot
I3NI25
resolver
uniprot_entry
CEP20_HUMAN
resolver
uniprot_entry
I3L269_HUMAN
resolver
uniprot_entry
I3L2N4_HUMAN
resolver
uniprot_entry
I3L4V2_HUMAN
resolver
uniprot_entry
I3NI25_HUMAN
resolver
uniprot_sec
B3KPU9
resolver
amino_acid_sequence
MATVAELKAVLKDTLEKKGVLGHLKARIRAEVFNALDDDREPRPSLSHENLLINELIREYLEFNKYKYTASVLIAESGQPVVPLDRQFLIHELNAFEESKDNTIPLLYGILAHFLRGTKDGIQNAFLKGPSLQPSDPSLGRQPSRRKPMDDHLRKEEQKSTNIEDLHVSQAVNR
uniprot
proteins
function
FUNCTION: Involved in the biogenesis of cilia (PubMed:20551181). Required for the recruitment of PLK1 to centrosomes and S phase progression (PubMed:24018379). {ECO:0000269|PubMed:20551181, ECO:0000269|PubMed:24018379}.
uniprot
proteins
mass_dalton
19778
uniprot
proteins
mutagenesis
MUTAGEN 49; /note="E->A: Loss of homooligomerization and loss of localization to centrosomes and pericentriolar satellites; when associated with A-76."; /evidence="ECO:0000269|PubMed:20551181"; MUTAGEN 49; /note="E->A: Strongly decreased interaction with KIAA0753; when associated with A-76."; /evidence="ECO:0000269|PubMed:26643951"; MUTAGEN 53; /note="I->Q: Loss of interaction with KIAA0753; when associated with A-76."; /evidence="ECO:0000269|PubMed:26643951"; MUTAGEN 76; /note="E->A: Loss of homooligomerization and loss of localization to centrosomes and pericentriolar satellites; when associated with A-49."; /evidence="ECO:0000269|PubMed:20551181"; MUTAGEN 76; /note="E->A: Strongly decreased interaction with KIAA0753; when associated with A-49. Loss of interaction with KIAA0753; when associated with Q-53."; /evidence="ECO:0000269|PubMed:26643951"; MUTAGEN 106; /note="L->R: No effect on interaction with KIAA0753."; /evidence="ECO:0000269|PubMed:26643951
uniprot
proteins
protein_family
CEP43 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
20551181
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24018379
uniprot
proteins
pubmed
26643951
uniprot
proteins
sequence_length
174
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:26643951}. Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20551181, ECO:0000269|PubMed:24018379}. Cytoplasmic granule {ECO:0000269|PubMed:20551181}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:20551181, ECO:0000269|PubMed:26643951}. Note=Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951). {ECO:0000269|PubMed:24018379, ECO:0000269|PubMed:26643951}.
uniprot
proteins