H2AL3
entrez
115482686
canonical
uniprot
A0A3B3IU63
canonical
ensembl
ENSG00000229674
resolver
ensp
ENSP00000498087
resolver
enst
ENST00000448797
resolver
genesymbol
H2AL3
resolver
genesymbol_syn
H2AL1RP
resolver
hgnc
HGNC:53960
resolver
uniprot_entry
H2AL3_HUMAN
resolver
amino_acid_sequence
MAGNKMFCRPRRQRLSHSRRAELQFPVSHLERCLRESQHARHLSSTTPVFLAGVLEYLTANILEKVGKEVKNSCRLCITPEHVKRALQKDEQLRWILELEDDTHSQVEEMPQSEEEEEEEEEKEEEMVVLVVMGGRRRRRRRRRRKDS
uniprot
proteins
function
FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. {ECO:0000305}.
uniprot
proteins
mass_dalton
17661
uniprot
proteins
protein_family
Histone H2A family
uniprot
proteins
pubmed
15772651
uniprot
proteins
sequence_length
148
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. Chromosome {ECO:0000305}.
uniprot
proteins