RPS8
entrez
6202
canonical
uniprot
P62241
canonical
ensembl
ENSG00000142937
resolver
ensp
ENSP00000379888
resolver
ensp
ENSP00000602964
resolver
enst
ENST00000396651
resolver
enst
ENST00000932905
resolver
genesymbol
RPS8
resolver
hgnc
HGNC:10441
resolver
uniprot
P09058
resolver
uniprot
Q5JR94
resolver
uniprot
Q6IRL7
resolver
uniprot_entry
Q5JR94_HUMAN
resolver
uniprot_entry
RS8_HUMAN
resolver
uniprot_sec
P09058
resolver
uniprot_sec
Q6IRL7
resolver
amino_acid_sequence
MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK
uniprot
proteins
function
FUNCTION: Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). {ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:34516797}.
uniprot
proteins
mass_dalton
24205
uniprot
proteins
protein_family
Eukaryotic ribosomal protein eS8 family
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17289661
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23636399
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24524803
uniprot
proteins
pubmed
25255805
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
34516797
uniprot
proteins
pubmed
8432552
uniprot
proteins
pubmed
8706699
uniprot
proteins
sequence_length
208
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17289661, ECO:0000269|PubMed:23636399}. Membrane {ECO:0000305|PubMed:17289661}; Lipid-anchor {ECO:0000305|PubMed:17289661}. Nucleus, nucleolus {ECO:0000269|PubMed:34516797}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000269|PubMed:17289661}.
uniprot
proteins