TAF6L
entrez
10629
canonical
uniprot
Q9Y6J9
canonical
ensembl
ENSG00000162227
resolver
ensp
ENSP00000294168
resolver
ensp
ENSP00000523583
resolver
ensp
ENSP00000523586
resolver
ensp
ENSP00000607047
resolver
ensp
ENSP00000607050
resolver
ensp
ENSP00000607052
resolver
ensp
ENSP00000607054
resolver
ensp
ENSP00000607055
resolver
ensp
ENSP00000607057
resolver
enst
ENST00000294168
resolver
enst
ENST00000853524
resolver
enst
ENST00000853527
resolver
enst
ENST00000936991
resolver
enst
ENST00000936993
resolver
enst
ENST00000936995
resolver
enst
ENST00000936996
resolver
enst
ENST00000936998
resolver
genesymbol
TAF6L
resolver
genesymbol_syn
PAF65A
resolver
hgnc
HGNC:17305
resolver
uniprot
A8K0D4
resolver
uniprot
B2RAT0
resolver
uniprot
Q96HA6
resolver
uniprot_entry
A8K0D4_HUMAN
resolver
uniprot_entry
TAF6L_HUMAN
resolver
uniprot_sec
B2RAT0
resolver
uniprot_sec
Q96HA6
resolver
amino_acid_sequence
MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYHQVTRAVLGDDPQLMKVALQDLQTNSKIGALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLFRNPHLCLGPYVRCLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQHILLSLQKILADPVRPLCCHYGAVVGLHALGWKAVERVLYPHLSTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGPGGRGCRRLDDLPWDSLLFQESSSGGGAEPSFGSGLPLPPGGAGPEDPSLSVTLADIYRELYAFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPDSVRKMPQLTASAIVSPHGDESPRGSGGGGPASASGPAASESRPLPRVHRARGAPRQQGPGTGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTSRPARRWALSDYSLYLPL
uniprot
proteins
function
FUNCTION: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable). With TAF5L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state. Functions with MYC to activate target gene expression through RNA polymerase II pause release (By similarity). {ECO:0000250|UniProtKB:Q8R2K4, ECO:0000305|PubMed:9674419}.
uniprot
proteins
mass_dalton
67814
uniprot
proteins
protein_family
TAF6 family
uniprot
proteins
pubmed
11564863
uniprot
proteins
pubmed
12601814
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
9674419
uniprot
proteins
pubmed
9674425
uniprot
proteins
sequence_length
622
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11564863, ECO:0000269|PubMed:9674425}.
uniprot
proteins