F6WEQ6
uniprot
F6WEQ6
canonical
amino_acid_sequence
MASPVADASRRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPVPQKGLQYLVLLSHTHSRECSLVPGLRGPGGGEGELVWECSAGHTFSWEPSLIPTPSEVPKQAPLTHTTERTWCSEARRKQEAEGLECEHRERTQETRLSRRVEPPLETDPSVGEDQVVEEEEEEEEEEEEEELLSDASPWTYSSSPDDSEPDVPRPPPSPVTHTPKEGEIPPVPATLPTPCAVLASLGSTAALTSDTEVQMELSRTSQVPAELQMTESLDSPGSQAQSAPNPTCDEDTAQIGLRRIRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFCCPEPACGKSFNFKKHLKEHVKLHSDARDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHRRKHAETAAALRFPCEFCGKRFEKPDSVVAHCSKSHPALLPVQESPGSLGSSPSISAPEPLQSPEGTSFSTSYDSNPAPSTSISSPGVPAPRNTEKS
uniprot
proteins
function
FUNCTION: May act as an transcriptional repressor for PCK1 gene expression, in turns may participate in the hepatic gluconeogenesis regulation through the activated AMPK signaling pathway. {ECO:0000269|PubMed:17097062}.
uniprot
proteins
mass_dalton
59219
uniprot
proteins
post_translational_modification
PTM: Phosphorylation at Ser-471 results in loss of DNA-binding activity. {ECO:0000250|UniProtKB:Q9BU19}.
uniprot
proteins
protein_family
Krueppel C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17097062
uniprot
proteins
sequence_length
533
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9BU19}.
uniprot
proteins