Agbl1
entrez
244071
canonical
uniprot
Q09M05
canonical
ensembl
ENSMUSG00000025754
resolver
ensp
ENSMUSP00000119721
resolver
enst
ENSMUST00000156166
resolver
genesymbol
Agbl1
resolver
genesymbol_syn
Ccp4
resolver
uniprot
D3Z1M2
resolver
uniprot
Q8C768
resolver
uniprot_entry
CBPC4_MOUSE
resolver
uniprot_entry
D3Z1M2_MOUSE
resolver
uniprot_sec
Q8C768
resolver
amino_acid_sequence
MAEQEGSGLQMLLHTLQNSSDKASTLSILQVLGDLLSVGTDRRIYYMISKGGSEALLQTLVDTARSSSPDWDILLPLFRLLAKVGLRDKKFGQKALELEALDVTLILARKNLSHSQNLLHCLWVLRVFASSVTTGAMLGINGAMELLFKVLSPYTRKHTRTIRAATEVLAALLKSSKHLRRAVNRGYVNSLLRLHQDWHSRDVTNTYVTIRHGLLLCLRHIVALRSGREAFLAAQGMETLFSSAQTCLENKNMELVISAVIQILRQCYPASRLPLVTASSAYTFPAPGSTSSELPLNLTEEDFDDDGDEEMDKDSDVEAVKEDDDLETDLSKLSSKPGLDLPEEELAQYDAMCPELSCSFEELEPKCGDDLNNKDTLHANHHHIPSVASLRQHCFNREHSSWRQEREDTVHSSILHMVKTGKSGVPSSSKQRSATNVNQSLQQNGLEIDSSGHDTSDIQAPLEQAAWDMEAISCPRITASFPNSTKPEESIGAAEKLLHTHAKHIPFHDPHLYIANAMRTRSAVGFKTMAFPDLWGHCPPPAAQPMLDRKLGVQRIKILEDIRRLLHPSDVINKVVFSLDEPRPLQGSISNCLMFHSKFESGNLRKAIQVREFEYDLLVNADVNSSQHQQWFYFKVSGMRAAVPYHFNIINCEKPNSQFNYGMQPTLYSVKEALLGRPAWIRTGSDICYYKNHYRQNAATMDGALGKRYYTLTFAVTFPHNEDACYLAYHYPYTYSTLMTHLEILERSIDHREIYFRHDVLCQTLGGNPCPLVTITAFPESNSTEHLEQFRCRPYQVITARVHPGESNASWVMKGTLEFLVSSDPVAKLLRENFVFKIIPMLNPDGVINGNHRCSLRGEDLNRQWLSPQAHLQPTIYHAKGLLHYLSSTGRGPVVFCDFHGHSQKKNVFLYGCSMKETLWQAGCTVGESALLEDVSYRTLPKILDKLAPAFTMNSCSFLVEKSRASTARVVVWREMGVSRSYTMESSYCGCNQGPYQGLQFGTGELEEMGAMYCLGLLILELKSVNCSHKLLARASSLLNADVLEHYLQRCSSSSSNSSNRTSEVDDEPYCMEEIDYSADSSSDAEQNFTELDRQIQECALNKDEEEEEKEEGTGWRRRSVT
uniprot
proteins
ec_number
3.4.17.-
uniprot
proteins
ec_number
3.4.17.24
uniprot
proteins
function
FUNCTION: Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins (PubMed:21074048). Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein (PubMed:21074048). Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate (PubMed:21074048). Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK (PubMed:21074048). {ECO:0000269|PubMed:21074048}.
uniprot
proteins
mass_dalton
126149
uniprot
proteins
mutagenesis
MUTAGEN 803; /note="H->S: Abolishes deglutamylase activity; when associated with Q-806."; /evidence="ECO:0000269|PubMed:21074048"; MUTAGEN 806; /note="E->Q: Abolishes deglutamylase activity; when associated with S-803."; /evidence="ECO:0000269|PubMed:21074048
uniprot
proteins
protein_family
Peptidase M14 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17244818
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21074048
uniprot
proteins
pubmed
25103237
uniprot
proteins
sequence_length
1122
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q96MI9}.
uniprot
proteins