Pex39
entrez
67101
canonical
uniprot
Q9D727
canonical
ensembl
ENSMUSG00000062619
resolver
ensp
ENSMUSP00000071378
resolver
enst
ENSMUST00000071430
resolver
genesymbol
Pex39
resolver
uniprot
Q9D1N0
resolver
uniprot_entry
PEX39_MOUSE
resolver
uniprot_sec
Q9D1N0
resolver
amino_acid_sequence
MSWWQDMDQRGGVSSPSGALASAEPAPASVTLAELLHLVQKGQEVPGLEKRHITATHGEPTASLLPRRPKPWEDAGSAASPCTIALDTRTQPPTIEERSRGSPAAQLDGGPRVS
uniprot
proteins
function
FUNCTION: Cytosolic peroxin that promotes the peroxisomal import of proteins containing a type-2 peroxisomal targeting signal (PTS2) by binding to PEX7 and stabilizing its interaction with PTS2-containing cargo. PEX39 subsequently transfers the PEX7-cargo complex to PEX13 at the peroxisomal membrane, enabling PEX7 to bind PEX13 and facilitating translocation of PTS2-containing proteins into the peroxisome. Both PEX39 and PEX13 contain a conserved KPWE motif, which enables competitive binding to PEX7 and ensures efficient handover of the complex. {ECO:0000250|UniProtKB:Q5I0X4}.
uniprot
proteins
mass_dalton
12013
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
114
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q5I0X4}.
uniprot
proteins