Gsta1
entrez
14857
canonical
uniprot
P13745
canonical
ensembl
ENSMUSG00000074183
resolver
ensp
ENSMUSP00000096139
resolver
enst
ENSMUST00000098537
resolver
genesymbol
Gsta1
resolver
genesymbol_syn
Gsta
resolver
genesymbol_syn
Gstya
resolver
uniprot
A2RTN4
resolver
uniprot_entry
GSTA1_MOUSE
resolver
uniprot_sec
A2RTN4
resolver
amino_acid_sequence
MAGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFKIQ
uniprot
proteins
ec_number
1.11.1.-
uniprot
proteins
ec_number
2.5.1.18
uniprot
proteins
ec_number
5.3.3.-
uniprot
proteins
function
FUNCTION: Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (PubMed:9606968). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid (By similarity). {ECO:0000250|UniProtKB:P08263, ECO:0000269|PubMed:9606968, ECO:0000305|PubMed:11027134}.
uniprot
proteins
mass_dalton
25608
uniprot
proteins
protein_family
Alpha family
uniprot
proteins
protein_family
GST superfamily
uniprot
proteins
pubmed
11027134
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2049074
uniprot
proteins
pubmed
3652905
uniprot
proteins
pubmed
9606968
uniprot
proteins
sequence_length
223
uniprot
proteins