Rgs16
entrez
19734
canonical
uniprot
P97428
canonical
ensembl
ENSMUSG00000026475
resolver
ensp
ENSMUSP00000027748
resolver
enst
ENSMUST00000027748
resolver
genesymbol
Rgs16
resolver
genesymbol_syn
Rgsr
resolver
uniprot
O09091
resolver
uniprot
P97420
resolver
uniprot
Q542U0
resolver
uniprot
Q80V16
resolver
uniprot_entry
Q542U0_MOUSE
resolver
uniprot_entry
RGS16_MOUSE
resolver
uniprot_sec
O09091
resolver
uniprot_sec
P97420
resolver
uniprot_sec
Q80V16
resolver
amino_acid_sequence
MCRTLATFPNTCLERAKEFKTRLGIFLHKSELSSDTGGISKFEWASKHNKERSFSEDVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASATSTSAPSGSPAEPSHT
uniprot
proteins
function
FUNCTION: Regulates G protein-coupled receptor signaling cascades (PubMed:9079700). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10373502). Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha (PubMed:8917514). May regulate extra and intracellular mitogenic signals. {ECO:0000269|PubMed:10373502, ECO:0000269|PubMed:8917514, ECO:0000305}.
uniprot
proteins
mass_dalton
22691
uniprot
proteins
post_translational_modification
PTM: Palmitoylated on Cys-2 and/or Cys-12. {ECO:0000269|PubMed:10373502}.; PTM: Phosphorylated. Phosphorylation at Tyr-167 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1. {ECO:0000250|UniProtKB:O15492}.
uniprot
proteins
pubmed
10373502
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18434540
uniprot
proteins
pubmed
8917514
uniprot
proteins
pubmed
9079700
uniprot
proteins
pubmed
9223279
uniprot
proteins
pubmed
9469939
uniprot
proteins
sequence_length
201
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:10373502}; Lipid-anchor {ECO:0000269|PubMed:10373502}.
uniprot
proteins