Garem1
entrez
381126
canonical
uniprot
Q3UFT3
canonical
ensembl
ENSMUSG00000042680
resolver
ensp
ENSMUSP00000048914
resolver
genesymbol
Garem1
resolver
genesymbol_syn
Fam59a
resolver
genesymbol_syn
Garem
resolver
genesymbol_syn
Gm944
resolver
genesymbol_syn
Kiaa4238
resolver
uniprot
G5E8B7
resolver
uniprot
Q3TSA2
resolver
uniprot
Q5DTF6
resolver
uniprot
Q80V96
resolver
uniprot_entry
GARE1_MOUSE
resolver
uniprot_sec
G5E8B7
resolver
uniprot_sec
Q3TSA2
resolver
uniprot_sec
Q5DTF6
resolver
uniprot_sec
Q80V96
resolver
amino_acid_sequence
MDPAPSLGCSLKDVKWSPVAMPLDLLVSTYRLPQIARLDSGECVEGLRENDFLLIHSCRQWTTITAHSLEEGHYVIGPKIEIPVHYAGQFKLLEQDRDIKEPVQYFNSVEEVAKAFPERVYVMEEITFNVKVASGECNEDTEVYNITLCTGDELTLMGQAEILYAKTFKEKSRLNTIFKKIGKLNSISKLGKGKMPCLICMNHRTNESISLPFQCKGRFSTRSPLELQMQEGEHTIRNIVEKTRLPVNVTVPSPPPRNPYDLHFIREGHRYKFVNIQTKTVVVCCVLRNNKILPMHFPLHLTVPKFSLPEHQVKGDMWPETLVHHWLGICQEQFDIDEYSRAVRDVKTDWNEDCKSPKKGRCSGHNHLPNSLSYARDELTQSFHRLSVCVYGNNLHGNSEVNLHGCRDLGGEWAPFPHDILPYQDSGDSGSDYLFPEANEESAGIPGKTEVPYEELWLEEGKPSRQPLTRSLSEKSRCDTLRGSTRSTCAPSSPPTPATLGATIKSSEIALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPVRPQTRSPSPTLSYYSSGLHNIITQSDTSPPNSAPVSCYPCTRVKSDSVDPKSPFGSPSAEALSSRLSWPNHYSGASENQTRSDFLLDPSRSYSYPRQKTPGTPKRTCPAPFDFEGCELLGSPPSTTSAEFSSSGVPSCPKSASYCLENSEDNSFAAGMTKQSVSCPALPPRAPKPVEQKATPETSPLPLKIDGAEEDPTAGSLDLSEDQYFVRKGMQDIFSVSYPFSSPLHLQLAPRSCGDGSPWQPPADLSGLSIEEVSKSLRFIGLSEDVIAFFVTEKIDGNLLVQLTEEILSEDFKLSKLQVKKILQFINGWRPKI
uniprot
proteins
function
FUNCTION: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
97250
uniprot
proteins
post_translational_modification
PTM: On EGF stimulation, phosphorylated on Tyr-105 and Tyr-453. {ECO:0000250}.
uniprot
proteins
protein_family
GAREM family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
876
uniprot
proteins