PSMG1
entrez
8624
canonical
uniprot
O95456
canonical
ensembl
ENSG00000183527
resolver
ensp
ENSP00000329915
resolver
ensp
ENSP00000370286
resolver
ensp
ENSP00000559224
resolver
genesymbol
PSMG1
resolver
genesymbol_syn
C21LRP
resolver
genesymbol_syn
DSCR2
resolver
genesymbol_syn
PAC1
resolver
hgnc
HGNC:3043
resolver
uniprot
B5BUN2
resolver
uniprot
Q6FHA3
resolver
uniprot
Q6FHD3
resolver
uniprot
Q6S713
resolver
uniprot_entry
PSMG1_HUMAN
resolver
uniprot_sec
B5BUN2
resolver
uniprot_sec
Q6FHA3
resolver
uniprot_sec
Q6FHD3
resolver
uniprot_sec
Q6S713
resolver
amino_acid_sequence
MAATFFGEVVKAPCRAGTEDEEEEEEGRRETPEDREVRLQLARKREVRLLRRQTKTSLEVSLLEKYPCSKFIIAIGNNAVAFLSSFVMNSGVWEEVGCAKLWNEWCRTTDTTHLSSTEAFCVFYHLKSNPSVFLCQCSCYVAEDQQYQWLEKVFGSCPRKNMQITILTCRHVTDYKTSESTGSLPSPFLRALKTQNFKDSACCPLLEQPNIVHDLPAAVLSYCQVWKIPAILYLCYTDVMKLDLITVEAFKPILSTRSLKGLVKNIPQSTEILKKLMTTNEIQSNIYT
uniprot
proteins
function
FUNCTION: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. {ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17707236}.
uniprot
proteins
mass_dalton
32854
uniprot
proteins
post_translational_modification
PTM: Degraded by the proteasome upon completion of 20S proteasome maturation.
uniprot
proteins
protein_family
PSMG1 family
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
10872820
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15590417
uniprot
proteins
pubmed
15670775
uniprot
proteins
pubmed
16251969
uniprot
proteins
pubmed
17707236
uniprot
proteins
pubmed
19054851
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23495936
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26109405
uniprot
proteins
pubmed
9784380
uniprot
proteins
sequence_length
288
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Endoplasmic reticulum.
uniprot
proteins