Cfp
entrez
18636
canonical
uniprot
P11680
canonical
ensembl
ENSMUSG00000001128
resolver
ensp
ENSMUSP00000001156
resolver
enst
ENSMUST00000001156
resolver
genesymbol
Cfp
resolver
genesymbol_syn
Pfc
resolver
uniprot
A2AE15
resolver
uniprot
Q3TB98
resolver
uniprot
Q3U779
resolver
uniprot_entry
A2AE15_MOUSE
resolver
uniprot_entry
PROP_MOUSE
resolver
uniprot_sec
Q3TB98
resolver
uniprot_sec
Q3U779
resolver
amino_acid_sequence
MPAEMQAPQWLLLLLVILPATGSDPVLCFTQYEESSGRCKGLLGRDIRVEDCCLNAAYAFQEHDGGLCQACRSPQWSAWSLWGPCSVTCSEGSQLRHRRCVGRGGQCSENVAPGTLEWQLQACEDQPCCPEMGGWSEWGPWGPCSVTCSKGTQIRQRVCDNPAPKCGGHCPGEAQQSQACDTQKTCPTHGAWASWGPWSPCSGSCLGGAQEPKETRSRSCSAPAPSHQPPGKPCSGPAYEHKACSGLPPCPVAGGWGPWSPLSPCSVTCGLGQTLEQRTCDHPAPRHGGPFCAGDATRNQMCNKAVPCPVNGEWEAWGKWSDCSRLRMSINCEGTPGQQSRSRSCGGRKFNGKPCAGKLQDIRHCYNIHNCIMKGSWSQWSTWSLCTPPCSPNATRVRQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGTPRPLCEALQGQKLVVEEKRSCLHVPVCKDPEEKKP
uniprot
proteins
function
FUNCTION: A positive regulator of the alternate pathway of complement (PubMed:28264884). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (By similarity). Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (By similarity). {ECO:0000250|UniProtKB:P27918, ECO:0000269|PubMed:28264884}.
uniprot
proteins
mass_dalton
50327
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
28264884
uniprot
proteins
pubmed
3045564
uniprot
proteins
sequence_length
464
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P27918}.
uniprot
proteins