IVL
entrez
3713
canonical
uniprot
P07476
canonical
ensembl
ENSG00000163207
resolver
ensp
ENSP00000357753
resolver
enst
ENST00000368764
resolver
genesymbol
IVL
resolver
hgnc
HGNC:6187
resolver
uniprot
Q5T7P4
resolver
uniprot_entry
INVO_HUMAN
resolver
uniprot_sec
Q5T7P4
resolver
amino_acid_sequence
MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK
uniprot
proteins
function
FUNCTION: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
uniprot
proteins
mass_dalton
68479
uniprot
proteins
post_translational_modification
PTM: Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide.
uniprot
proteins
protein_family
Involucrin family
uniprot
proteins
pubmed
15147942
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1601889
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
2461365
uniprot
proteins
pubmed
2873896
uniprot
proteins
pubmed
9115270
uniprot
proteins
pubmed
9651377
uniprot
proteins
sequence_length
585
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
uniprot
proteins