Crhbp
entrez
12919
canonical
uniprot
Q60571
canonical
ensembl
ENSMUSG00000021680
resolver
ensp
ENSMUSP00000152083
resolver
enst
ENSMUST00000221025
resolver
genesymbol
Crhbp
resolver
uniprot
Q3UY07
resolver
uniprot_entry
CRHBP_MOUSE
resolver
uniprot_entry
Q3UY07_MOUSE
resolver
amino_acid_sequence
MSPNFKLQCHFILILLTALRGESRYLEVQEAAVYDPLLLFSANLKRDLAEEQPYRRALRCLDMLSLPGQFTFTADRPQLHCAAFFIGEPEEFITIHYDLVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPTMKRYTDFCESGLTRRSIRSSQNVAMVFFRVHEPGNGFTITIKTDPNLFPCNVISQTPSGRFTLVVPYQHQNCSFSIIYPVAIKISDLTLGHLHGLQLKKPAAGCGGTGDFVELLGGTGLDPSKMMPLADLCYPFLGPAQMKISCDNAVVRMVSSGKHINRVTFEYRQLEPFELETSTGNSIPEYCLSSL
uniprot
proteins
function
FUNCTION: Specifically binds and inactivates the corticotropin-releasing hormone (CRH) and urocortin-1 (UCN) hormones, thereby inhibiting the hypothalamus-pituitary-adrenal axis and preventing corticotropin hormone (ACTH) production (PubMed:27641503, PubMed:7556876). May be required to prevent inappropriate pituitary-adrenal stimulation in pregnancy (By similarity). {ECO:0000250|UniProtKB:P24387, ECO:0000269|PubMed:27641503, ECO:0000269|PubMed:7556876}.
uniprot
proteins
mass_dalton
36048
uniprot
proteins
protein_family
CRF-binding protein family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
27641503
uniprot
proteins
pubmed
7556876
uniprot
proteins
sequence_length
322
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P24387}.
uniprot
proteins