Catsperz
entrez
67077
canonical
uniprot
Q9CQP8
canonical
ensembl
ENSMUSG00000050623
resolver
ensp
ENSMUSP00000056681
resolver
enst
ENSMUST00000057716
resolver
genesymbol
Catsperz
resolver
genesymbol_syn
Tex40
resolver
uniprot
Q9DAA2
resolver
uniprot
Q9DAP8
resolver
uniprot_entry
CTSRZ_MOUSE
resolver
uniprot_sec
Q9DAA2
resolver
uniprot_sec
Q9DAP8
resolver
amino_acid_sequence
MEESVKPVPKHANHRRSSVRSSLYGDVRDLWSTATMSTANVSVSDVCEDFDEEGKSVRNRIRKYSQTISIRDSLNLEPEEIQQQARRELELCHGRSLEHGEDHEESETSLASSTSESLIFSLWKPHRTYWTEQQNRLPLPLMELMETEVLDILKKALITYRSTIGRNHFMTKELQGYIEGIRKRRNKRLYFLDQ
uniprot
proteins
function
FUNCTION: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation (PubMed:28226241, PubMed:31056283, PubMed:34225353). Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (PubMed:28226241, PubMed:31056283). Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract (PubMed:28226241). Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel (PubMed:31056283). {ECO:0000269|PubMed:28226241, ECO:0000269|PubMed:31056283, ECO:0000269|PubMed:34225353}.
uniprot
proteins
mass_dalton
22741
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20339383
uniprot
proteins
pubmed
28226241
uniprot
proteins
pubmed
31056283
uniprot
proteins
pubmed
34225353
uniprot
proteins
sequence_length
194
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:28226241}; Peripheral membrane protein {ECO:0000305}. Note=Specifically located in the principal piece of sperm tail (PubMed:28226241). Although it does not contain a transmembrane domain, localizes with the CatSper complex at the flagellum membrane (PubMed:28226241). {ECO:0000269|PubMed:28226241}.
uniprot
proteins