Rasef
entrez
242505
canonical
uniprot
Q5RI75
canonical
ensembl
ENSMUSG00000043003
resolver
ensp
ENSMUSP00000062771
resolver
ensp
ENSMUSP00000099901
resolver
ensp
ENSMUSP00000152127
resolver
genesymbol
Rasef
resolver
uniprot
A0A1D8RIR4
resolver
uniprot
A0A1Y7VIT3
resolver
uniprot
B2RQ59
resolver
uniprot
Q5RI76
resolver
uniprot_entry
A0A1D8RIR4_MOUSE
resolver
uniprot_entry
RASEF_MOUSE
resolver
uniprot_sec
A0A1Y7VIT3
resolver
uniprot_sec
B2RQ59
resolver
uniprot_sec
Q5RI76
resolver
amino_acid_sequence
MEADADPEELTRLRSVFATYDTNGSGRLERAEFSALCAELHVAEAEAEAVFRGLDTDRDGAITFPEFARGFRGALGRDSAEAQGAWEVAEPESPSPAWRDFHARLGDEAQLIPRKEQVSTLYQNITLVEPRLLQPYERVIRNFLREIKLQSTEMENLAIAVKRAQDKAAIQLSELEEEMDQRIQAVENESRKDEKRKAEEALTDLRRQYETEVGDLQVTIKRLKKLEEQSRQISQKQDVTALKKQIHDLTMENQKLKKELLEAQTNVAFLQSELDALKSDYADQSLNSERDLEIIREYTEDRSSLERQIEILQTANRKLHDSNDGLRSALENTYSKLNRSLRINNISPGNTISRSSPKFNHHSSQPLAYDRSFHSSYADEDCDSLALCDPLQKMNYEVDSLPESCFDSGLSTLRDNECDSEVDYKHQGEFQTLHRTEESLGGDASDTDVPDIRDEEAFDSESVASVLHWQPQGSAGEGSTLSSSRKPISALSLQTDMVDNTSKVTSQKAYKIVLAGDAAVGKSSFLMRLCKNEFQGNTSATLGVDFQMKTLIVDGEQTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNVREWVDMVEDGTHRTIPIMLVGNKADLRDVDNAENQKCISAYLGEKLAMTYGALFCETSAKDGSNVVEAVLHLAREVKKRTEDDDSRSITSLAGSTSKKSLQMKNCCNG
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: [Isoform 3]: Rab GTPase that acts as a dynein adapter protein, thereby activating dynein-mediated transport and dynein-dynactin motility on microtubules (By similarity). RASEF-mediated dynein motility is Ca(2+)-independent (By similarity). Also regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells (PubMed:38901651). {ECO:0000250|UniProtKB:Q8IZ41, ECO:0000269|PubMed:38901651}.
uniprot
proteins
mass_dalton
79548
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
38901651
uniprot
proteins
sequence_length
708
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8IZ41}. Cytoplasm {ECO:0000250|UniProtKB:Q8IZ41}. Golgi apparatus {ECO:0000250|UniProtKB:Q8IZ41}. Early endosome {ECO:0000250|UniProtKB:Q8IZ41}. Late endosome {ECO:0000269|PubMed:38901651}. Lysosome {ECO:0000269|PubMed:38901651}. Note=Mostly diffusely distributed in the cytoplasm and partially localized to Golgi and endo-lysosomes in pancreatic cells. {ECO:0000269|PubMed:38901651}.
uniprot
proteins