HLA-DOB
entrez
3112
canonical
uniprot
P13765
canonical
ensembl
ENSG00000239457
resolver
ensembl
ENSG00000241106
resolver
ensembl
ENSG00000241386
resolver
ensembl
ENSG00000241910
resolver
ensembl
ENSG00000243496
resolver
ensembl
ENSG00000243612
resolver
ensp
ENSP00000390020
resolver
ensp
ENSP00000394783
resolver
ensp
ENSP00000395780
resolver
ensp
ENSP00000397268
resolver
ensp
ENSP00000405108
resolver
ensp
ENSP00000410390
resolver
ensp
ENSP00000496848
resolver
enst
ENST00000426644
resolver
enst
ENST00000438763
resolver
enst
ENST00000447178
resolver
enst
ENST00000454286
resolver
enst
ENST00000454969
resolver
enst
ENST00000456406
resolver
enst
ENST00000648009
resolver
genesymbol
HLA-DOB
resolver
hgnc
HGNC:4937
resolver
uniprot
B0V0Y0
resolver
uniprot
Q29746
resolver
uniprot
Q29825
resolver
uniprot
Q5QNS2
resolver
uniprot
Q6FHC2
resolver
uniprot_entry
DOB_HUMAN
resolver
uniprot_entry
Q5QNS2_HUMAN
resolver
uniprot_sec
B0V0Y0
resolver
uniprot_sec
Q29746
resolver
uniprot_sec
Q29825
resolver
uniprot_sec
Q6FHC2
resolver
amino_acid_sequence
MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLRAQKGYVRTQMSGNEVSRAVLLPQSC
uniprot
proteins
function
FUNCTION: Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
uniprot
proteins
mass_dalton
30822
uniprot
proteins
protein_family
MHC class II family
uniprot
proteins
pubmed
10837054
uniprot
proteins
pubmed
12445321
uniprot
proteins
pubmed
1453454
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2499532
uniprot
proteins
pubmed
2998758
uniprot
proteins
pubmed
3036827
uniprot
proteins
pubmed
8568858
uniprot
proteins
sequence_length
273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
uniprot
proteins
transmembrane_region
TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins