Kcna10
entrez
242151
canonical
uniprot
B2RQA1
canonical
ensembl
ENSMUSG00000042861
resolver
ensp
ENSMUSP00000088118
resolver
enst
ENSMUST00000055064
resolver
genesymbol
Kcna10
resolver
uniprot
B2RXZ4
resolver
uniprot_entry
KCA10_MOUSE
resolver
uniprot_sec
B2RXZ4
resolver
activity_regulation
ACTIVITY REGULATION: The channel activity is up-regulated by cAMP. {ECO:0000250|UniProtKB:Q16322}.
uniprot
proteins
amino_acid_sequence
MDVCSWKEMEVALVNFDNSDEIHEEPGYATDFDPTSSKGRPGSSPFSNWRVLISDNTNHETAFSKIPGEYVDPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLNQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDVFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDFHRQFWLLFEYPESSSAARGVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPSINTNKTGLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFKNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKPNIPGELDKILNSMGSRMGSTESLNKTNGSCSAEKSRK
uniprot
proteins
function
FUNCTION: Voltage-gated potassium ion channel that mediates K(+) permeability of excitable membranes. When opened in response to the voltage difference across the membrane, KCNA10 channel selectively allows the flow of potassium ions across the membrane down their electrochemical gradient. {ECO:0000250|UniProtKB:Q16322}.
uniprot
proteins
mass_dalton
57968
uniprot
proteins
protein_family
A (Shaker) (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv1.8/KCNA10 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22446089
uniprot
proteins
pubmed
23528307
uniprot
proteins
sequence_length
511
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 218..238; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 271..292; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 303..323; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 339..358; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 375..395; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 436..456; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins