Nkiras1
entrez
69721
canonical
uniprot
Q8CEC5
canonical
ensembl
ENSMUSG00000021772
resolver
ensp
ENSMUSP00000121496
resolver
ensp
ENSMUSP00000260124
resolver
enst
ENSMUST00000132374
resolver
genesymbol
Nkiras1
resolver
uniprot
Q9JKV3
resolver
uniprot_entry
KBRS1_MOUSE
resolver
uniprot_sec
Q9JKV3
resolver
amino_acid_sequence
MGKGCKVVICGLLSVGKTAILEQLLYGNHTIGMEDCETLEDVYMASVETDRGVKEQLHLYDTRGLQKGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKLDLSEQRQVDADVAQQWARSEKVKLWEVTVTDRRTLIEPFTLLASKLSQPQSKSSFPLPGRKNKGNSNPEN
uniprot
proteins
function
FUNCTION: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
21662
uniprot
proteins
protein_family
KappaB-Ras subfamily
uniprot
proteins
protein_family
Ras family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
10657303
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
192
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins