HINT2
entrez
84681
canonical
uniprot
Q9BX68
canonical
ensembl
ENSG00000137133
resolver
ensp
ENSP00000259667
resolver
ensp
ENSP00000665094
resolver
enst
ENST00000259667
resolver
genesymbol
HINT2
resolver
hgnc
HGNC:18344
resolver
uniprot
Q5TCW3
resolver
uniprot_entry
HINT2_HUMAN
resolver
uniprot_sec
Q5TCW3
resolver
amino_acid_sequence
MAAAVVLAAGLRAARRAVAATGVRGGQVRGAAGVTDGNEVAKAQQATPGGAAPTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQLQWPPG
uniprot
proteins
ec_number
3.9.1.-
uniprot
proteins
function
FUNCTION: Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:16762638, PubMed:31990367). Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) (PubMed:16762638). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed:31990367). May be involved in steroid biosynthesis (PubMed:18653718). May play a role in apoptosis (PubMed:16762638). {ECO:0000269|PubMed:16762638, ECO:0000269|PubMed:18653718, ECO:0000269|PubMed:31990367}.
uniprot
proteins
mass_dalton
17162
uniprot
proteins
mutagenesis
MUTAGEN 149; /note="H->A: Loss of adenosine phosphoramidase activity."; /evidence="ECO:0000269|PubMed:16762638
uniprot
proteins
protein_family
HINT family
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16762638
uniprot
proteins
pubmed
18653718
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23659632
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28968488
uniprot
proteins
pubmed
31990367
uniprot
proteins
sequence_length
163
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16762638, ECO:0000269|PubMed:18653718}.
uniprot
proteins