CPO
entrez
130749
canonical
uniprot
Q8IVL8
canonical
ensembl
ENSG00000144410
resolver
ensp
ENSP00000272852
resolver
ensp
ENSP00000800850
resolver
enst
ENST00000272852
resolver
genesymbol
CPO
resolver
hgnc
HGNC:21011
resolver
uniprot
Q2M277
resolver
uniprot
Q7RTW7
resolver
uniprot_entry
CBPO_HUMAN
resolver
uniprot_sec
Q2M277
resolver
uniprot_sec
Q7RTW7
resolver
activity_regulation
ACTIVITY REGULATION: Strongly inhibited by potato carboxypeptidase inhibitor, and the chelating agents EDTA and 1,10-phenanthroline. Also inhibited by compounds with multiple carboxylic acid groups such as citrate and succinate, and to a lesser exent the amino acids aspartate and glutamate. Not significantly inhibited by benzylsuccinic acid. {ECO:0000269|PubMed:21921028}.
uniprot
proteins
amino_acid_sequence
MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGRVTSATMLLGLLVSCMSLL
uniprot
proteins
ec_number
3.4.17.-
uniprot
proteins
function
FUNCTION: Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins. Can also cleave C-terminal hydrophobic amino acids, with a preference for small residues over large residues. {ECO:0000269|PubMed:21921028}.
uniprot
proteins
mass_dalton
42529
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:21921028}.
uniprot
proteins
protein_family
Peptidase M14 family
uniprot
proteins
pubmed
11836249
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
21921028
uniprot
proteins
sequence_length
374
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:21921028}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:21921028}.
uniprot
proteins