HOXB13
entrez
10481
canonical
uniprot
Q92826
canonical
ensembl
ENSG00000159184
resolver
ensp
ENSP00000290295
resolver
enst
ENST00000290295
resolver
genesymbol
HOXB13
resolver
hgnc
HGNC:5112
resolver
uniprot
B2R878
resolver
uniprot
Q4KR72
resolver
uniprot
Q96QM4
resolver
uniprot
Q99810
resolver
uniprot_entry
HXB13_HUMAN
resolver
uniprot_entry
Q4KR72_HUMAN
resolver
uniprot_sec
B2R878
resolver
uniprot_sec
Q96QM4
resolver
uniprot_sec
Q99810
resolver
amino_acid_sequence
MEPGNYATLDGAKDIEGLLGAGGGRNLVAHSPLTSHPAAPTLMPAVNYAPLDLPGSAEPPKQCHPCPGVPQGTSPAPVPYGYFGGGYYSCRVSRSSLKPCAQAATLAAYPAETPTAGEEYPSRPTEFAFYPGYPGTYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQSWALAGGWNSQMCCQGEQNPPGPFWKAAFADSSGQHPPDACAFRRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKNSATP
uniprot
proteins
disease_involvement
DISEASE: Prostate cancer, hereditary, 9 (HPC9) [MIM:610997]: A condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. {ECO:0000269|PubMed:22236224, ECO:0000269|PubMed:22714738, ECO:0000269|PubMed:23064873, ECO:0000269|PubMed:23292082, ECO:0000269|PubMed:25629170, ECO:0000269|PubMed:27424772}. Note=Disease susceptibility is associated with variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds preferentially to methylated DNA (PubMed:28473536). {ECO:0000269|PubMed:28473536}.
uniprot
proteins
mass_dalton
30676
uniprot
proteins
protein_family
Abd-B homeobox family
uniprot
proteins
pubmed
11857506
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22236224
uniprot
proteins
pubmed
22714738
uniprot
proteins
pubmed
23064873
uniprot
proteins
pubmed
23292082
uniprot
proteins
pubmed
25629170
uniprot
proteins
pubmed
27424772
uniprot
proteins
pubmed
28473536
uniprot
proteins
pubmed
8756292
uniprot
proteins
pubmed
9665387
uniprot
proteins
sequence_length
284
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins