GPR87
entrez
53836
canonical
uniprot
Q9BY21
canonical
ensembl
ENSG00000138271
resolver
ensp
ENSP00000260843
resolver
enst
ENST00000260843
resolver
genesymbol
GPR87
resolver
genesymbol_syn
GPR95
resolver
hgnc
HGNC:4538
resolver
uniprot
Q5KU35
resolver
uniprot
Q96JZ8
resolver
uniprot
Q9BXC2
resolver
uniprot_entry
GPR87_HUMAN
resolver
uniprot_sec
Q5KU35
resolver
uniprot_sec
Q96JZ8
resolver
uniprot_sec
Q9BXC2
resolver
amino_acid_sequence
MGFNLTLAKLPNNELHGQESHNSGNRSDGPGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWHTAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV
uniprot
proteins
function
FUNCTION: Receptor for lysophosphatidic acid (LPA) (PubMed:17905198). Necessary for p53/TP53-dependent survival in response to DNA damage (PubMed:19602589). Promotes the Hippo-YAP signaling pathway and thereby modulates glycolysis and oxidative stress production by the regulation of hexokinase-2/HK2 (PubMed:35843477). {ECO:0000269|PubMed:17905198, ECO:0000269|PubMed:19602589, ECO:0000269|PubMed:35843477}.
uniprot
proteins
mass_dalton
41436
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11273702
uniprot
proteins
pubmed
11574155
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17905198
uniprot
proteins
pubmed
19602589
uniprot
proteins
pubmed
35843477
uniprot
proteins
sequence_length
358
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 48..68; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 160..180; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 257..277; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 298..318; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins