MYLK3
entrez
91807
canonical
uniprot
Q32MK0
canonical
ensembl
ENSG00000140795
resolver
ensp
ENSP00000378288
resolver
ensp
ENSP00000439297
resolver
genesymbol
MYLK3
resolver
genesymbol_syn
MLCK
resolver
hgnc
HGNC:29826
resolver
uniprot
B5BUL9
resolver
uniprot
B7Z5U8
resolver
uniprot
Q32MK1
resolver
uniprot
Q96DV1
resolver
uniprot_entry
MYLK3_HUMAN
resolver
uniprot_sec
B5BUL9
resolver
uniprot_sec
B7Z5U8
resolver
uniprot_sec
Q32MK1
resolver
uniprot_sec
Q96DV1
resolver
amino_acid_sequence
MSGTSKESLGHGGLPGLGKTCLTTMDTKLNMLNEKVDQLLHFQEDVTEKLQSMCRDMGHLERGLHRLEASRAPGPGGADGVPHIDTQAGWPEVLELVRAMQQDAAQHGARLEALFRMVAAVDRAIALVGATFQKSKVADFLMQGRVPWRRGSPGDSPEENKERVEEEGGKPKHVLSTSGVQSDAREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVPGPAQAFPGHLPLPTKVEAKAPETPSENLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDTPGEMLMTGRGSLGPTLTTEAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEGARELSPLQESSSPGGVKAEEEQRAGAEPGTRPSLARSDDNDHEVGALGLQQGKSPGAGNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
uniprot
proteins
ec_number
2.7.11.18
uniprot
proteins
function
FUNCTION: Kinase that phosphorylates MYL2 in vitro (By similarity). Has been proposed to be calmodulin-dependent, although MYL2 phosphorylation has also been observed in the presence or absence of calmodulin (By similarity). Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity). {ECO:0000250|UniProtKB:E9PT87, ECO:0000250|UniProtKB:Q3UIZ8}.
uniprot
proteins
mass_dalton
88393
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on serine residues. {ECO:0000250|UniProtKB:Q3UIZ8}.
uniprot
proteins
protein_family
CAMK Ser/Thr protein kinase family
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17885681
uniprot
proteins
pubmed
19054851
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
819
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q3UIZ8}.
uniprot
proteins