SSX1
entrez
6756
canonical
uniprot
Q16384
canonical
ensembl
ENSG00000126752
resolver
ensp
ENSP00000366118
resolver
ensp
ENSP00000762814
resolver
enst
ENST00000376919
resolver
genesymbol
SSX1
resolver
hgnc
HGNC:11335
resolver
uniprot
A3KN76
resolver
uniprot
Q08AJ2
resolver
uniprot
Q5JQ64
resolver
uniprot_entry
SSX1_HUMAN
resolver
uniprot_sec
A3KN76
resolver
uniprot_sec
Q08AJ2
resolver
uniprot_sec
Q5JQ64
resolver
amino_acid_sequence
MNGDDTFAKRPRDDAKASEKRSKAFDDIATYFSKKEWKKMKYSEKISYVYMKRNYKAMTKLGFKVTLPPFMCNKQATDFQGNDFDNDHNRRIQVEHPQMTFGRLHRIIPKIMPKKPAEDENDSKGVSEASGPQNDGKQLHPPGKANISEKINKRSGPKRGKHAWTHRLRERKQLVIYEEISDPEEDDE
uniprot
proteins
disease_involvement
DISEASE: Spermatogenic failure, X-linked, 5 (SPGFX5) [MIM:301099]: A male infertility disorder characterized by reduced progressive sperm motility and multiple morphologic sperm abnormalities, resulting in asthenoteratozoospermia. {ECO:0000269|PubMed:36796361}. Note=The disease may be caused by variants affecting the gene represented in this entry.; DISEASE: Note=A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). {ECO:0000269|PubMed:7539744}.
uniprot
proteins
function
FUNCTION: Could act as a modulator of transcription (PubMed:7539744). Plays a role in spermatogenesis (PubMed:36796361). {ECO:0000269|PubMed:36796361, ECO:0000269|PubMed:7539744}.
uniprot
proteins
mass_dalton
21931
uniprot
proteins
protein_family
SSX family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
36796361
uniprot
proteins
pubmed
7539744
uniprot
proteins
pubmed
7655467
uniprot
proteins
sequence_length
188
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:36796361}.
uniprot
proteins