RHEX
entrez
440712
canonical
uniprot
Q6ZWK4
canonical
ensembl
ENSG00000263961
resolver
ensp
ENSP00000356093
resolver
ensp
ENSP00000463990
resolver
ensp
ENSP00000474994
resolver
ensp
ENSP00000541827
resolver
ensp
ENSP00000541829
resolver
ensp
ENSP00000541830
resolver
ensp
ENSP00000541831
resolver
ensp
ENSP00000541832
resolver
ensp
ENSP00000629983
resolver
enst
ENST00000331555
resolver
enst
ENST00000582070
resolver
enst
ENST00000603488
resolver
enst
ENST00000871768
resolver
enst
ENST00000871770
resolver
enst
ENST00000871771
resolver
enst
ENST00000871772
resolver
enst
ENST00000871773
resolver
enst
ENST00000959924
resolver
genesymbol
RHEX
resolver
genesymbol_syn
C1orf186
resolver
hgnc
HGNC:25341
resolver
uniprot_entry
RHEX_HUMAN
resolver
amino_acid_sequence
MLTEVMEVWHGLVIAVVSLFLQACFLTAINYLLSRHMAHKSEQILKAASLQVPRPSPGHHHPPAVKEMKETQTERDIPMSDSLYRHDSDTPSDSLDSSCSSPPACQATEDVDYTQVVFSDPGELKNDSPLDYENIKEITDYVNVNPERHKPSFWYFVNPALSEPAEYDQVAM
uniprot
proteins
function
FUNCTION: Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation (PubMed:25092874). {ECO:0000269|PubMed:25092874}.
uniprot
proteins
mass_dalton
19405
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. Phosphorylation on Tyr-132 and Tyr-141 occurs in a erythropoietin (EPO)-dependent manner (PubMed:25092874). {ECO:0000269|PubMed:25092874}.
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
25092874
uniprot
proteins
sequence_length
172
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:25092874}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins