Pigt
entrez
78928
canonical
uniprot
Q8BXQ2
canonical
ensembl
ENSMUSG00000017721
resolver
ensp
ENSMUSP00000099390
resolver
ensp
ENSMUSP00000112577
resolver
enst
ENSMUST00000103101
resolver
enst
ENSMUST00000117066
resolver
genesymbol
Pigt
resolver
genesymbol_syn
Ndap7
resolver
uniprot
A2A5G2
resolver
uniprot
B7ZC19
resolver
uniprot
Q3U2X2
resolver
uniprot
Q3U5R2
resolver
uniprot
Q99JA3
resolver
uniprot_entry
B7ZC19_MOUSE
resolver
uniprot_entry
PIGT_MOUSE
resolver
uniprot_entry
Q3U5R2_MOUSE
resolver
uniprot_sec
A2A5G2
resolver
uniprot_sec
Q3U2X2
resolver
uniprot_sec
Q99JA3
resolver
amino_acid_sequence
MAAAMPLGLPLRLLVLLLVGRGCCGCAEGPRDSLREELVITPLPSGDVAATFQFRTRWDSDLQREGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQDTVTDVDKSWRELSNVLSGIFCASLNFIDATNTVTPTASFKPLGLANDTDDYFLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPICRNAHCTSISWELRQTLSVVFDAFITGQGKKDWSLFRMFSRTLTEACPLASQSLVYVDITGYSQDNETLEVSPPPTSTYQDVILGTRKTYAVYDLFDTAMINNSRNLNIQLKWKRPPDNEALPVPFLHAQRYVSGYGLQKGELSTLLYNSHPYRAFPVLLLDVVPWYLRLYVHTLTITSKGKENKPSYIHYQPAQDRQQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSVVAAKPVDWEGSPLFNTLFPVSDGSSYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPKSGGLAKRLANLIRRARGVPPL
uniprot
proteins
function
FUNCTION: Component of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. May play a crucial role in GPI-T complex assembly in the luminal layer (By similarity). Binds GPI-anchor (By similarity). {ECO:0000250|UniProtKB:Q969N2}.
uniprot
proteins
mass_dalton
65705
uniprot
proteins
pathway_participation
PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis. {ECO:0000250|UniProtKB:Q969N2}.
uniprot
proteins
post_translational_modification
PTM: The disulfide bond between PIGK/GPI8 and PIGT is important for normal enzyme activity. {ECO:0000250|UniProtKB:Q969N2}.
uniprot
proteins
protein_family
PIGT family
uniprot
proteins
pubmed
11700951
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
582
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q969N2}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q969N2}.
uniprot
proteins
transmembrane_region
TRANSMEM 530..552; /note="Helical"; /evidence="ECO:0000250|UniProtKB:Q969N2
uniprot
proteins