SCD
entrez
6319
canonical
uniprot
O00767
canonical
ensembl
ENSG00000099194
resolver
ensp
ENSP00000359380
resolver
ensp
ENSP00000554378
resolver
enst
ENST00000370355
resolver
enst
ENST00000884319
resolver
genesymbol
SCD
resolver
genesymbol_syn
FADS5
resolver
genesymbol_syn
SCD1
resolver
genesymbol_syn
SCDOS
resolver
hgnc
HGNC:10571
resolver
uniprot
B2R5U0
resolver
uniprot
D3DR68
resolver
uniprot
Q16150
resolver
uniprot
Q53GR9
resolver
uniprot
Q5W037
resolver
uniprot
Q5W038
resolver
uniprot
Q6GSS4
resolver
uniprot
Q96KF6
resolver
uniprot
Q9BS07
resolver
uniprot
Q9Y695
resolver
uniprot_entry
SCD_HUMAN
resolver
uniprot_sec
B2R5U0
resolver
uniprot_sec
D3DR68
resolver
uniprot_sec
Q16150
resolver
uniprot_sec
Q53GR9
resolver
uniprot_sec
Q5W037
resolver
uniprot_sec
Q5W038
resolver
uniprot_sec
Q6GSS4
resolver
uniprot_sec
Q96KF6
resolver
uniprot_sec
Q9BS07
resolver
uniprot_sec
Q9Y695
resolver
amino_acid_sequence
MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLEDDIRPDIKDDIYDPTYKDKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWLWGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYYKPGLLMMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPYDKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAILARIKRTGDGNYKSG
uniprot
proteins
ec_number
1.14.19.1
uniprot
proteins
function
FUNCTION: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). {ECO:0000250|UniProtKB:P13516, ECO:0000269|PubMed:15610069, ECO:0000269|PubMed:15907797, ECO:0000269|PubMed:18765284}.
uniprot
proteins
mass_dalton
41523
uniprot
proteins
protein_family
Fatty acid desaturase type 1 family
uniprot
proteins
pubmed
10229681
uniprot
proteins
pubmed
11415448
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15610069
uniprot
proteins
pubmed
15907797
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
18765284
uniprot
proteins
pubmed
19892738
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
26098317
uniprot
proteins
pubmed
7909540
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15907797}; Multi-pass membrane protein {ECO:0000269|PubMed:18765284, ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000269|PubMed:26098317"; TRANSMEM 98..118; /note="Helical"; /evidence="ECO:0000269|PubMed:26098317"; TRANSMEM 218..237; /note="Helical"; /evidence="ECO:0000269|PubMed:26098317"; TRANSMEM 242..263; /note="Helical"; /evidence="ECO:0000269|PubMed:26098317
uniprot
proteins