HAPLN4
entrez
404037
canonical
uniprot
Q86UW8
canonical
ensembl
ENSG00000187664
resolver
ensp
ENSP00000291481
resolver
enst
ENST00000291481
resolver
genesymbol
HAPLN4
resolver
genesymbol_syn
BRAL2
resolver
genesymbol_syn
KIAA1926
resolver
hgnc
HGNC:31357
resolver
uniprot
A5PKW5
resolver
uniprot
Q96PW2
resolver
uniprot_entry
HPLN4_HUMAN
resolver
uniprot_sec
A5PKW5
resolver
uniprot_sec
Q96PW2
resolver
amino_acid_sequence
MVCARAALGPGALWAAAWGVLLLTAPAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFTDVFVALGPQHRAFGSYRGRAELQGDGPGDASLVLRNVTLQDYGRYECEVTNELEDDAGMVKLDLEGVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRARCGGRRPGVRSLGFPDATRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGARDPAAWTPLHV
uniprot
proteins
function
FUNCTION: Essential for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs (By similarity). Contributes to the formation and transmission of inhibitory GABAergic synapses between Purkinje cells and deep cerebellar nuclei neurons (By similarity). {ECO:0000250|UniProtKB:Q80WM4}.
uniprot
proteins
mass_dalton
42801
uniprot
proteins
protein_family
HAPLN family
uniprot
proteins
pubmed
11572484
uniprot
proteins
pubmed
12663660
uniprot
proteins
pubmed
14550776
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
402
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9ESM3}.
uniprot
proteins