Syncrip
entrez
363113
canonical
uniprot
Q7TP47
canonical
ensembl
ENSRNOG00000000204
resolver
ensembl
ENSRNOG00055017437
resolver
ensembl
ENSRNOG00060012376
resolver
ensembl
ENSRNOG00065012619
resolver
ensp
ENSRNOP00000048433
resolver
ensp
ENSRNOP00000065252
resolver
ensp
ENSRNOP00000075015
resolver
ensp
ENSRNOP00055023698
resolver
ensp
ENSRNOP00060016572
resolver
ensp
ENSRNOP00065015814
resolver
enst
ENSRNOT00000041655
resolver
enst
ENSRNOT00000078891
resolver
enst
ENSRNOT00055029508
resolver
enst
ENSRNOT00060021000
resolver
enst
ENSRNOT00065020561
resolver
genesymbol
Syncrip
resolver
genesymbol_syn
Hnrpq
resolver
uniprot
A0A0G2K9J1
resolver
uniprot_entry
A0A0G2K9J1_RAT
resolver
uniprot_entry
HNRPQ_RAT
resolver
amino_acid_sequence
MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSENEEFYQDTFGQQWK
uniprot
proteins
function
FUNCTION: Heterogeneous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Is associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Binds to apoB mRNA AU-rich sequences. Part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. May be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
59710
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine. The membrane-bound form found in microsomes is phosphorylated in vitro by insulin receptor tyrosine kinase (INSR). Phosphorylation is inhibited upon binding to RNA, whereas the cytoplasmic form is poorly phosphorylated.
uniprot
proteins
sequence_length
533
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250|UniProtKB:O43390}. Cytoplasm {ECO:0000250|UniProtKB:O43390}. Nucleus {ECO:0000250|UniProtKB:Q7TMK9}. Microsome {ECO:0000250|UniProtKB:Q7TMK9}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity). Expressed predominantly in the nucleoplasm. The tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity). {ECO:0000250|UniProtKB:O43390, ECO:0000250|UniProtKB:Q7TMK9}.
uniprot
proteins