Dnah1
entrez
171339
canonical
uniprot
Q63164
canonical
ensembl
ENSRNOG00000026914
resolver
ensembl
ENSRNOG00065014510
resolver
ensp
ENSRNOP00000059841
resolver
enst
ENSRNOT00000066508
resolver
genesymbol
Dnah1
resolver
genesymbol_syn
Dlp1
resolver
uniprot
D3ZRN8
resolver
uniprot_entry
D3ZRN8_RAT
resolver
uniprot_entry
DYH1_RAT
resolver
amino_acid_sequence
MVTLSISDTLHTPAFVENRHLAITGMPTRKANNGFPSPDDNNVWGQFWKDLQTPLLVVVYVHGAQCQLLLPIENRRVSSGSDKSLKNGMEECDKEEASTSSQGPGYCPANVPENHDLEKMLKESSRNPEKTSPNPELKTPPLPLSDLGQPRKSPLAGTDKKYPIMKQRGFYSDILSPGTLDQLGDVCCGPYLSQNLIRQADLDKFTPKGQCHEHWAAESFVIPEDFQERVEQQSIGTTTRLLTQTDFPLQSYEPKVQVPFQVLPGRCPRKIEIERRKQQYLRLDIEQLLANEGIDSNKLMPRHPDLQQPQTIEQGRDPLFPIYLPLKVFDNEEFDCRTPTEWLNMGLEPDAQYRKPVPGKALLPTDDALGHVHRAGCKQVSFSKCINTGISLPEAGKKQSVSFTLDSNDRNNLTKLSPVLQCLAIKPWEQGHVKCTEFQLPRFTGALALSRNTRAKRGSQEASTRDHLDFEDPKSQELDYRWCEVGVLDYDEEKKLYLVQKTDKRGLVRDEMGMPIVNGGVTPEGRPPLLDTQYWVPRIQLLFCAEDPRVFTQRVVQANALRKNTEALLLYNLYVDCMPTEGQRVINEQSLSKIKQWALSTPRMRKGPSVLEHLSSLAREVNLDYERSMNKINFDQIVSSKPETFSFVTLPEKEEEKVPNQGLVSVPEYPFREQKEDFTFVSLLTRSEVITALSKVRAECNKVTSMSLFHSNLSKYSRLEEFEQIQSQTFSQVQMFLKDSWISTLKVAMRSSLRDMSKGWYNLYETNWEVYLMSKLRKLMELIKYMLQDTLRFLVQDSLGSFAQFIGDACCSVLECIDDMDWGEDLINSPYKPRKNPLFIVDLVLDNTGVHYSTPLEQFEVILLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLESVGLHEPLVEELRANITNAMHKAMIPLQAYAKEYRKTYQTQCPSAEEVREVVITHLKEKEILDNSLPSSIIIGPFYINVDNVKQSLSKKRKALATSMLDILAKNLHNEVDSICEEFRSISRKIYEKPNSIEELAELRDWMKGIPEKLVILEVRQALALAARSLVEPEVGPALEIPFNNPLPSMTRHFLLMQERIVKVMSDYEVMDEFFYNLTTDDFNDKWAANNWPTKILGQIDMVRQQHVEDEEKFRKIQLMDQNNFQEKLEGLQLVVAGFSTHVEIARAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFGLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVIESFKTMHKCVKQFKDIPACQDVALDIRARIDEFKPYIPLIQGLRNPGMRNRHWEVLSNEININVRPKANLTFARCLEMNLQDYIESISKVAEVAGKEYAIEQALDKMEKEWASILFNVLPYKETDTYILKSPDEASQLLDDHIVMTQSMSFSPYKKPFEQRINSWETKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDITRQLPVESKRYQTMERIWRKIMKNAYENREVINVCSDQRLLDSLRDCNKLLDLVQKGLSEYLETKRTAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVKLSFSIYPSSNVEDWLLEVERSMKASVHDIIEMAIKAYPTMLRTEWVLSWPGQVTIAGCQTYWTLEVAQALEASSISSSLFPQLSKQLSDLVALVRGKLSRMQRMVLSALIVIEVHAKDVVSKLIDENVVSVHDFEWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRSREYIKSLGGAVMCLPFLCVLYVQALFRPVAMMVPDYAMIAEISLYSFGFNEANVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPTMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTTKEEETDYGILDQAIRKACEKNNLKDVEGFLIKCIQLYETTVVRHGLMLVGPTGSGKSNCYRILAAAMTSLKGKPSISGGVYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFPSLIRAGAIASDTNKKWYMFDGPVDAVWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFVECWLKHLPSIIKPYEEQFKTLFVKFLESSIAFVRTTVKEVVASTNSNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSHIPELIEPWFIFSLVWSVGATGDHSSRLNFSQWLKIKMVFEQIKLAFPEEGLVYDYRLDDAGISSTEDDDEDDEESKQVATALPAQEGGMVKPPGLWDLPPRDSGHLEKATLTASRSEAVAWVKWMDYSVPFTMMPDTNYCNIIVPTMDTMQMSYLLGMLITNHKPVLCIGPTGTGKTLTVSNKLLKNLPLEYISHFLTFSARTSANQTQDLIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNAITPRLTRHFNYLSFIEMDEVSKKRIFSIILGCWMDGLLGEKSYREPVPGAPNIVHMTEPLVNATISIYAIITSQLLPTPAKSHYTFNLRDLSKVFQGILMAEPAKVEDKVQLLRLWYHENCRVFRDRLVNEEDRGWFDGLLEMKMEDLGVAFNKVCPFQPILYGDFMSPGSDVKSYELITSENKMMQVIEEYMEDYNQINTAKLKLVLFVDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQVELSKNYGMSEWREDVKKILLKAGMQNLPITFLFSDTQIKNESFLEDINNILNSGDIPNLYSADEQDQIVNTMRPYIQEQGLQPTKANLMAAYTGRVRNNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALQSVATRFLHEIPELECSSEVIEGLIHVCVYIHQSVAKKCVEYLAELARHNYVTPKSYLELLNIFSILIGQKKMELKTAKHRMKSGLDKLLRTSEDVAKMQEELEIMRPLLEEAAKDTLLTMDQIKVDTAIAEETRKSVQAEEIKANEKASKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGSKVDDYWEPGKGLLQDPGRFLESLFKFDKDNIGEAVIKAIQPYIDNEEFQPAAIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALREAQDDLEVTQRILEEAKHHLREVEDGISTLQAKYRECVTKKEELEMKCEQCEQRLGRADKSQSPGQPPGAHPTRLLLQLINGLADEKVRWQDTVENLENMLDNIFGDVLVAAGFVAYLGPFTGQYRAALYEYWVNQLTVYGVPHTSKPTLISTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQGQANKWIKNMEKESGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYSPEVSTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDVELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAVRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRIVNINRYLTFSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQGEWRYLLSGGSIQTMSENPAPHWLSDRAWRDILALSNLPAFSTFSTDFVQHLPKFQAIFDSAEPHREPLPGIWNTYLDEFQKLLILRCLRGDKVTNAMQDFVANHLEPRFIEPQTANLSAVFKESNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRNSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVKANLLKSYNSLSDDFLHSCQKVVEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLDEYEDIPYKVLKYTAGEINYGGRVTDDWDRRCVMNILEDFYNPAVLSPEHRYSKSGIYHQIPPTYDLNGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALFGAILQLQPKSSSMGGQSREELVEDVAEDILVQVPKPVDLEEVVNKYPVLYEESMNTVLVQEVIRYNKLLMVITQTLSDMLKAIKGLVVMSLELELMSTSLYNNAVPELWKSKAYPSLKPLASWIMDLLQRLNFLHSWIKNGIPSVFWISGFFFPQAFLTGTLQNFARKFVISIDTITFDFKVLSYASSEIAERPSTGCYIYGLFLEGARWDPFDFQLAESRPKELYTEMAVIWLLPVANRKVQNQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPSNQPQRHWIKRGVALICALDY
uniprot
proteins
function
FUNCTION: Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme (By similarity). {ECO:0000250|UniProtKB:Q9P2D7}.
uniprot
proteins
mass_dalton
515021
uniprot
proteins
protein_family
Dynein heavy chain family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
7657712
uniprot
proteins
sequence_length
4516
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9P2D7}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:E9Q8T7}. Note=Recruitment to the sperm flagellum requires interaction with DNAH12. {ECO:0000250|UniProtKB:E9Q8T7}.
uniprot
proteins