Caveolin-mediated endocytosis of virus by host
uniprot_keyword
KW-1166
canonical
name
Caveolin-mediated endocytosis of virus by host
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synonym
Virion endocytosis by caveolin-coated vesicle
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definition
Viral protein involved in virus internalization by the host cell via caveolae, which are specialized lipid rafts that form 50-70 nm flask- shaped invaginations of the cell membrane. Caveolins form the structural backbone of caveolae. Internalization via caveolae is not a constitutive process but only occurs upon cell stimulation.Endocytic caveolae deliver their viral content to early endosomes. Caveolae represent a low capacity but highly regulated pathway. This pathway is used by viruses including HPV-31, BK virus, NDV, RSV, Coxsackie B virus, SV40, murine polyomavirus, and Echovirus 1.
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keywords
is_obsolete
false
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keywords
ontology_id
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keywords