Rnf133
entrez
386611
canonical
uniprot
Q14B02
canonical
ensembl
ENSMUSG00000051956
resolver
ensp
ENSMUSP00000066906
resolver
genesymbol
Rnf133
resolver
genesymbol_syn
Greul2
resolver
uniprot
Q8C1F1
resolver
uniprot
Q8CGR0
resolver
uniprot_entry
RN133_MOUSE
resolver
uniprot_sec
Q8C1F1
resolver
uniprot_sec
Q8CGR0
resolver
amino_acid_sequence
MNPLQTSTWQNQAPSFWLLRFSFIWLVSQKCCTASAVWTAYMNISFHVGNRMLSELGETGVFGRSSILKRVAGVVVPPEGKIQNACDPNTTFILPRNKEPWIALIERGGCAFTQKIKVASEHGARGVIIYNFPGTGNQVFPMSHQAFEDIVVVMIGNIKGMEILHLIRKGVHVTVMVEVGRKHVIWLNHYFVSFMIVTTATLAYFTFYHIRRLWVARIENRRWKRLTRELKKAFGQLQVRVLKEGDEEVNPNADSCVICFEAYKPNEIVRILTCKHFFHKNCIDPWILAHGTCPMCKCDILKALGIQMDIEDGTDSLQVLMSNELPGTLSPVEEETNYELPPARTSSKVTHVQEHPTSSANAGSQPPEAEETSHPSHGQQVL
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: Has E3 ubiquitin-protein ligase activity (PubMed:18574499). Plays a role in male fecundity through the interaction with the E2 ubituitin-protein ligase UBE2J1 (PubMed:35831855). {ECO:0000269|PubMed:18574499, ECO:0000269|PubMed:35831855}.
uniprot
proteins
mass_dalton
43102
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination. {ECO:0000269|PubMed:18574499}.
uniprot
proteins
post_translational_modification
PTM: Auto-ubiquitinated. {ECO:0000269|PubMed:18574499}.
uniprot
proteins
pubmed
12435366
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18574499
uniprot
proteins
pubmed
35831855
uniprot
proteins
sequence_length
382
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18574499, ECO:0000269|PubMed:35831855}; Single-pass membrane protein {ECO:0000305|PubMed:18574499}.
uniprot
proteins
transmembrane_region
TRANSMEM 190..210; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins