KHK
entrez
3795
canonical
uniprot
P50053
canonical
ensembl
ENSG00000138030
resolver
ensp
ENSP00000260598
resolver
ensp
ENSP00000260599
resolver
ensp
ENSP00000404741
resolver
ensp
ENSP00000578330
resolver
ensp
ENSP00000578331
resolver
ensp
ENSP00000578332
resolver
ensp
ENSP00000578333
resolver
ensp
ENSP00000786229
resolver
enst
ENST00000429697
resolver
genesymbol
KHK
resolver
hgnc
HGNC:6315
resolver
uniprot
A0A140VJM6
resolver
uniprot
C9JDL1
resolver
uniprot
Q6IBK2
resolver
uniprot
Q99532
resolver
uniprot
Q9BRJ3
resolver
uniprot
Q9UMN1
resolver
uniprot_entry
A0A140VJM6_HUMAN
resolver
uniprot_entry
C9JDL1_HUMAN
resolver
uniprot_entry
KHK_HUMAN
resolver
uniprot_sec
Q6IBK2
resolver
uniprot_sec
Q99532
resolver
uniprot_sec
Q9BRJ3
resolver
uniprot_sec
Q9UMN1
resolver
activity_regulation
ACTIVITY REGULATION: Requires potassium. Inhibition by ADP.
uniprot
proteins
amino_acid_sequence
MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
uniprot
proteins
disease_involvement
DISEASE: Fructosuria (FRUCT) [MIM:229800]: Benign defect of intermediary metabolism. {ECO:0000269|PubMed:12941785, ECO:0000269|PubMed:7833921}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
2.7.1.3
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate. {ECO:0000269|PubMed:12941785}.
uniprot
proteins
mass_dalton
32523
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; fructose metabolism.
uniprot
proteins
protein_family
Carbohydrate kinase PfkB family
uniprot
proteins
pubmed
12941785
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
19237742
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
7833921
uniprot
proteins
pubmed
9799106
uniprot
proteins
sequence_length
298
uniprot
proteins