Bcdin3d
entrez
363001
canonical
uniprot
D4ABH7
canonical
ensembl
ENSRNOG00000058430
resolver
ensembl
ENSRNOG00055029395
resolver
ensembl
ENSRNOG00060006497
resolver
ensembl
ENSRNOG00065021746
resolver
ensp
ENSRNOP00000070196
resolver
ensp
ENSRNOP00055041948
resolver
ensp
ENSRNOP00060007887
resolver
ensp
ENSRNOP00065029776
resolver
enst
ENSRNOT00000091538
resolver
enst
ENSRNOT00055050923
resolver
enst
ENSRNOT00060010642
resolver
enst
ENSRNOT00065036963
resolver
genesymbol
Bcdin3d
resolver
uniprot_entry
BN3D2_RAT
resolver
amino_acid_sequence
MAATQELSKGGVEEAVEEDDPAALKPGAAPFGNFPHYSRFHPPEQRLRLLPPELLRQLFPPEGPERRPILGLDVGCNSGDLSMALYKHFLSPHDGETSSGTSRELRLLCCDIDPVLVERAENGCRFPDALTFITLDIMDQESRKVPLSSFLSQFGRSVFDIVFCMSVTMWIHLNHGDRGLCEFLAHVSSLCSYLLVEPQPWKCYRAAARRLRKLGLHNFDHFRSLAIRGDMASQIVRILTQDHGMELACCFGNTSWDRSLLLFRAKHTEETQAIPESSTKETGTD
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
function
FUNCTION: O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145. {ECO:0000250|UniProtKB:Q7Z5W3}.
uniprot
proteins
mass_dalton
32002
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
285
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q7Z5W3}.
uniprot
proteins