Sec24a
entrez
77371
canonical
uniprot
Q3U2P1
canonical
ensembl
ENSMUSG00000036391
resolver
ensp
ENSMUSP00000044370
resolver
ensp
ENSMUSP00000104725
resolver
ensp
ENSMUSP00000295005
resolver
enst
ENSMUST00000038210
resolver
genesymbol
Sec24a
resolver
uniprot
A2AA70
resolver
uniprot
A2AA71
resolver
uniprot
A2AA73
resolver
uniprot
A4FUV4
resolver
uniprot
Q3TQ05
resolver
uniprot
Q3TRG7
resolver
uniprot
Q8BIS0
resolver
uniprot_entry
A2AA71_MOUSE
resolver
uniprot_entry
SC24A_MOUSE
resolver
uniprot_sec
A2AA70
resolver
uniprot_sec
A2AA73
resolver
uniprot_sec
A4FUV4
resolver
uniprot_sec
Q3TQ05
resolver
uniprot_sec
Q3TRG7
resolver
uniprot_sec
Q8BIS0
resolver
amino_acid_sequence
MAQPRIPAARGAAASLQAQNGAASASGSPYTNGPVHNTLMSPQVSSSQGYDSQPPGSYPRPMPAKTLNPFSAQSNYGGSQGSGQTLNSPLVTSGPVLPSLHSGPVPRMPLPTSQNPAATPMPSGSFLPGANPPPPLNWQYNYPSTGPQTNHFPHVAPPTLPGNPNLTADHQYVSSGDPALQTSFKKPGSALPLQNPPLPPTFQPGAPPGPPPAGGPPPSRGPAPQKTPPRAAPPPSFNSAVNQEGITSNANNGSTAAHNTYDEIEGGGFLATPQLVNQNPKTSRSVGSAYPSLPPGYQNSAPPVAGMPPPSLSYPSGPQAFTQTPLGANHLTASMSGLSLHPEGLRVVNLLQERNMLPSTPLQPPVPNLLEDIQKLNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRSCRTYINPFVNFLDQRRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYSLQEGLSQPQMLIVSDIDDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEIHLTPSTDFYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSSVLSGQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTSIRLDERIFAMCQVKSQPLVHLMLTTHPSLYRVDNLSDEGALNINDRTIPQPPILQLSVEKLSRDGAFLMDAGSLLMLWVGRNCSQNFLSQVLGVQNYASIPQTMTDLPELDTPESARIAAFISWLREQRPFFPVLYVIREESLMKAAFLQSLVEDRTESALSYYEFLLHIQQQVNK
uniprot
proteins
function
FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes. {ECO:0000250|UniProtKB:O95486}.
uniprot
proteins
mass_dalton
118782
uniprot
proteins
protein_family
SEC23/SEC24 family
uniprot
proteins
protein_family
SEC24 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1090
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:O95486}; Peripheral membrane protein {ECO:0000250|UniProtKB:O95486}; Cytoplasmic side {ECO:0000250|UniProtKB:O95486}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O95486}; Peripheral membrane protein {ECO:0000250|UniProtKB:O95486}; Cytoplasmic side {ECO:0000250|UniProtKB:O95486}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:O95486}.
uniprot
proteins