SLX4IP
entrez
128710
canonical
uniprot
Q5VYV7
canonical
ensembl
ENSG00000149346
resolver
ensp
ENSP00000335557
resolver
enst
ENST00000334534
resolver
genesymbol
SLX4IP
resolver
genesymbol_syn
C20orf94
resolver
hgnc
HGNC:16225
resolver
uniprot
Q05CG2
resolver
uniprot
Q05CT9
resolver
uniprot_entry
SLX4I_HUMAN
resolver
uniprot_sec
Q05CG2
resolver
uniprot_sec
Q05CT9
resolver
amino_acid_sequence
MASKKFAVKCGNFAVLVDLHILPQGSNKDTSWFSEQKKEEVCLLLKETIDSRVQEYLEVRKQHRPSNAEFTRSNPLSLKGYGFQITAYFLKRGIRLRCIRSTQNAELCVFPDRFVVCVSQLAFSRDLLASQNEDLTERVLHGVSDYFAECAESSLPPSAKLRRNALKEIVKRTETKSSVTSKSQTRRDTVETSSDSVIAEIARRRNDGQASSSPPSESMGQAKDSIKAAESHWGLPVQKLEKVNQTQPEDTSGQQKPHPGERLKTGLLSRSPVCSCESASPCPKQSPRVAKTQQKRRNCSSAEDFDHHGRVSLGSDRLVPREIIVEKSKAVRVLPASELSDPGLLLKQDLAKTTSKEELHVLESLSSRHLMKNNPGQAQQTGLATNTERLSTIQNSPTKKRKKYERGH
uniprot
proteins
disease_involvement
DISEASE: Note=Chromosomal aberrations involving SLX4IP are found in acute lymphoblastic leukemia. A site-specific deletion within the 5' region of SLX4IP is found in 30% of childhood acute lymphoblastic leukemia in general and more than 60% of ETV6/RUNX1-rearranged acute lymphoblastic leukemia. Breakpoints within SLX4IP reveal junctions with typical characteristics of illegitimate V(D)J mediated recombination. SLX4IP deletions are significantly associated with male gender and ETV6/RUNX1-rearranged acute lymphoblastic leukemia. {ECO:0000269|PubMed:24045615}.
uniprot
proteins
mass_dalton
45552
uniprot
proteins
protein_family
SLX4IP family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19596235
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24045615
uniprot
proteins
pubmed
25755297
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
408
uniprot
proteins