Slfn1
entrez
20555
canonical
uniprot
Q9Z0I7
canonical
ensembl
ENSMUSG00000078763
resolver
ensp
ENSMUSP00000047782
resolver
enst
ENSMUST00000037994
resolver
genesymbol
Slfn1
resolver
uniprot_entry
SLFN1_MOUSE
resolver
amino_acid_sequence
MNITDEGTPVLILNAGGITLGTESRKTMENHDRVEENRNITKALCALINSGEGKVKAHIKNPDYILSKHGIGEDLETSFKNILPSRPLDFKQYQSYFFICVEKSQSPDVSVGKPATIATNLYMRNGASSVEMNLDAAQKFLDNIKVAGGRSPSARPSDRPGDDTQEEGHIQELAAAFFKQSKLTKKENFLFSESKNVEYKSFETKKLLQRVKEILPRTVSAFANTDGGYLFIGLDEKKQEIVGFEAKNCQPKCLESEIEKCIQQLPVTHFCEEREKIKYKCKFIEVHDSGVVCKYVCALRVERFCCAVFAAEPESWHMKDGGVKRFTIEEWIKLLMS
uniprot
proteins
function
FUNCTION: Protein expressed in resting T-cells, which is required for maintaining T-cells in the quiescent state (PubMed:15946944, PubMed:18373498, PubMed:9846487). Acts by promoting cell-cycle arrest of T-cells through inhibiting the expression of cyclin-D1 (CCND1) (PubMed:15946944). {ECO:0000269|PubMed:15946944, ECO:0000269|PubMed:18373498, ECO:0000269|PubMed:9846487}.
uniprot
proteins
mass_dalton
37996
uniprot
proteins
protein_family
Schlafen family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15946944
uniprot
proteins
pubmed
18373498
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
9846487
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18373498}. Nucleus {ECO:0000269|PubMed:18373498}. Note=Translocates into the nucleus following interaction with DNAJB6. {ECO:0000269|PubMed:18373498}.
uniprot
proteins