DEF8
entrez
54849
canonical
uniprot
Q6ZN54
canonical
ensembl
ENSG00000140995
resolver
ensp
ENSP00000268676
resolver
ensp
ENSP00000412784
resolver
ensp
ENSP00000456095
resolver
ensp
ENSP00000456799
resolver
ensp
ENSP00000457627
resolver
ensp
ENSP00000458019
resolver
ensp
ENSP00000480073
resolver
ensp
ENSP00000482524
resolver
ensp
ENSP00000545178
resolver
ensp
ENSP00000545179
resolver
ensp
ENSP00000545180
resolver
ensp
ENSP00000545181
resolver
ensp
ENSP00000675281
resolver
genesymbol
DEF8
resolver
hgnc
HGNC:25969
resolver
uniprot
B3KT65
resolver
uniprot
B4DK62
resolver
uniprot
B4E0S9
resolver
uniprot
B7Z3H6
resolver
uniprot
H3BUG7
resolver
uniprot
Q8N8N3
resolver
uniprot
Q9NXL0
resolver
uniprot_entry
DEFI8_HUMAN
resolver
uniprot_sec
B3KT65
resolver
uniprot_sec
B4DK62
resolver
uniprot_sec
B4E0S9
resolver
uniprot_sec
B7Z3H6
resolver
uniprot_sec
H3BUG7
resolver
uniprot_sec
Q8N8N3
resolver
uniprot_sec
Q9NXL0
resolver
amino_acid_sequence
MAILSLRAPGPWQAMQVWADRTLLTPHTGVTSQVLGVAAAVMTPLPGGHAAGRTREARWDAMEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPERVMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQSLFQEPGPDVEA
uniprot
proteins
function
FUNCTION: Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption. {ECO:0000250|UniProtKB:Q99J78}.
uniprot
proteins
mass_dalton
58710
uniprot
proteins
protein_family
DEF8 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
22814378
uniprot
proteins
sequence_length
512
uniprot
proteins