EXOC3
entrez
11336
canonical
uniprot
O60645
canonical
ensembl
ENSG00000180104
resolver
ensp
ENSP00000323377
resolver
ensp
ENSP00000425587
resolver
ensp
ENSP00000599837
resolver
ensp
ENSP00000698639
resolver
enst
ENST00000315013
resolver
enst
ENST00000512944
resolver
enst
ENST00000929778
resolver
genesymbol
EXOC3
resolver
genesymbol_syn
SEC6
resolver
genesymbol_syn
SEC6L1
resolver
hgnc
HGNC:30378
resolver
uniprot
Q6P2E8
resolver
uniprot
Q8TEN6
resolver
uniprot
Q8WUW0
resolver
uniprot
Q96DI4
resolver
uniprot_entry
EXOC3_HUMAN
resolver
uniprot_sec
Q6P2E8
resolver
uniprot_sec
Q8TEN6
resolver
uniprot_sec
Q8WUW0
resolver
uniprot_sec
Q96DI4
resolver
amino_acid_sequence
MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQCFPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCSGLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPAQASPSYVPLFKDIVVPSLNVAKLLK
uniprot
proteins
function
FUNCTION: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
uniprot
proteins
mass_dalton
85567
uniprot
proteins
protein_family
SEC6 family
uniprot
proteins
pubmed
12693554
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18329369
uniprot
proteins
pubmed
18756269
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
20736409
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
745
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O54921}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54921}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54921}. Midbody {ECO:0000269|PubMed:18756269}. Golgi apparatus {ECO:0000305|PubMed:18756269}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q62825}. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269). {ECO:0000250|UniProtKB:O54921, ECO:0000269|PubMed:18756269}.
uniprot
proteins