SCAPER
entrez
49855
canonical
uniprot
Q9BY12
canonical
ensembl
ENSG00000140386
resolver
ensp
ENSP00000442190
resolver
ensp
ENSP00000454973
resolver
ensp
ENSP00000537467
resolver
ensp
ENSP00000537468
resolver
ensp
ENSP00000639295
resolver
ensp
ENSP00000639298
resolver
ensp
ENSP00000672703
resolver
ensp
ENSP00000776361
resolver
genesymbol
SCAPER
resolver
genesymbol_syn
KIAA1454
resolver
genesymbol_syn
ZNF291
resolver
hgnc
HGNC:13081
resolver
uniprot
F5H7X8
resolver
uniprot
H3BNR7
resolver
uniprot
Q3B7X7
resolver
uniprot
Q96BS9
resolver
uniprot
Q9H3D8
resolver
uniprot
Q9NT03
resolver
uniprot
Q9P274
resolver
uniprot_entry
SCAPE_HUMAN
resolver
uniprot_sec
F5H7X8
resolver
uniprot_sec
H3BNR7
resolver
uniprot_sec
Q3B7X7
resolver
uniprot_sec
Q96BS9
resolver
uniprot_sec
Q9H3D8
resolver
uniprot_sec
Q9NT03
resolver
uniprot_sec
Q9P274
resolver
amino_acid_sequence
MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTHKTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVTCESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGRHVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEITPAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDKENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTDYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLSLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSPYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGLTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELANRFPQQAWEEARQFFLKKEKK
uniprot
proteins
disease_involvement
DISEASE: Intellectual developmental disorder and retinitis pigmentosa (IDDRP) [MIM:618195]: An autosomal recessive disease characterized by mild to moderate intellectual disability, retinitis pigmentosa, and attention deficit-hyperactivity disorder observed in some patients. {ECO:0000269|PubMed:28794130}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm. {ECO:0000269|PubMed:17698606}.
uniprot
proteins
mass_dalton
158287
uniprot
proteins
mutagenesis
MUTAGEN 26..28; /note="RNL->AAA: No effect on CCNA2/CDK2 complex-binding."; /evidence="ECO:0000269|PubMed:17698606"; MUTAGEN 199..201; /note="RSL->AAA: Loss of CCNA2/CDK2 complex-binding."; /evidence="ECO:0000269|PubMed:17698606"; MUTAGEN 678..680; /note="RAL->AAA: No effect on CCNA2/CDK2 complex-binding."; /evidence="ECO:0000269|PubMed:17698606
uniprot
proteins
post_translational_modification
PTM: Phosphorylated in vitro by the CCNA2/CDK2 complex.
uniprot
proteins
pubmed
10819331
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
17698606
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28794130
uniprot
proteins
sequence_length
1400
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:17698606}. Nucleus {ECO:0000269|PubMed:17698606}. Note=Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus.
uniprot
proteins