Mks1
entrez
380718
canonical
uniprot
Q5SW45
canonical
ensembl
ENSMUSG00000034121
resolver
ensp
ENSMUSP00000043790
resolver
ensp
ENSMUSP00000335264
resolver
enst
ENSMUST00000038196
resolver
genesymbol
Mks1
resolver
uniprot
Q284W0
resolver
uniprot
Q3V3W3
resolver
uniprot_entry
MKS1_MOUSE
resolver
uniprot_entry
Q284W0_MOUSE
resolver
uniprot_sec
Q3V3W3
resolver
amino_acid_sequence
MAEAVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAQMGKDLIDLATFRPPQAASGHRPDEEEEEEVVIGWQEKLFSQFEVDLYQNESACQSPLDHQYRQEILKLENSGGRKNRRIFTYTDSDRYTDLEEYCQKITTSASEVPSFLAERMANVRRRRQDRRGVEGSKLKSRIVTWEPSEDFIKNNHAINTPLQTMYIMADLGPYGKLGYKVHEHVLCILKVDSNGVITVKPDFTGIKGPYRIETEGEKQEHTSAWKYTIDNVSSLAQPEEEEREQRVFKDLYGRHKEYLSSLVGTDFEMIAPGALRLFVNGEVVSAQGYEYDNLYVHFFVELPAANWSSPPFQQLSGVTQACATKSLGMDKVAYFSFPFTFEAFFLHEDESAESLPEWPVLYCKVLSLDFWQRYRVEGYGAVVLPATPGSHTLTVSTWRPMELGLVAELRRFFIGGSLELEDPSYVRIPGTFKGERLSRFGFRTETTGTVTFRLHCLQQSRAFMESNSLQKQMRSVLDRLEGFSQQSSTHNVLEAFRRARRRMQEARESLPQDLVSPTGTLT
uniprot
proteins
function
FUNCTION: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. {ECO:0000269|PubMed:17185389, ECO:0000269|PubMed:19515853, ECO:0000269|PubMed:21725307, ECO:0000269|PubMed:22179047}.
uniprot
proteins
mass_dalton
64416
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16415886
uniprot
proteins
pubmed
17185389
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19515853
uniprot
proteins
pubmed
21565611
uniprot
proteins
pubmed
21725307
uniprot
proteins
pubmed
21763481
uniprot
proteins
pubmed
22179047
uniprot
proteins
sequence_length
561
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:21725307}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
uniprot
proteins