Edf1
entrez
59022
canonical
uniprot
Q9JMG1
canonical
ensembl
ENSMUSG00000015092
resolver
ensp
ENSMUSP00000015236
resolver
ensp
ENSMUSP00000347065
resolver
enst
ENSMUST00000015236
resolver
genesymbol
Edf1
resolver
uniprot
Q99NE6
resolver
uniprot_entry
EDF1_MOUSE
resolver
uniprot_sec
Q99NE6
resolver
amino_acid_sequence
MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQRGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPKAK
uniprot
proteins
function
FUNCTION: Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. Might function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
16369
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250}.
uniprot
proteins
pubmed
10679242
uniprot
proteins
pubmed
11587857
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
148
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin. {ECO:0000250}.
uniprot
proteins