KCNG1
entrez
3755
canonical
uniprot
Q9UIX4
canonical
ensembl
ENSG00000026559
resolver
ensp
ENSP00000360626
resolver
ensp
ENSP00000524181
resolver
ensp
ENSP00000609858
resolver
ensp
ENSP00000609859
resolver
ensp
ENSP00000609861
resolver
ensp
ENSP00000609863
resolver
ensp
ENSP00000609866
resolver
ensp
ENSP00000609870
resolver
ensp
ENSP00000609871
resolver
ensp
ENSP00000609872
resolver
ensp
ENSP00000609878
resolver
genesymbol
KCNG1
resolver
hgnc
HGNC:6248
resolver
uniprot
A8K3S4
resolver
uniprot
O43528
resolver
uniprot
Q5JXL5
resolver
uniprot
Q86Y85
resolver
uniprot
Q9BRC1
resolver
uniprot_entry
KCNG1_HUMAN
resolver
uniprot_entry
Q86Y85_HUMAN
resolver
uniprot_sec
A8K3S4
resolver
uniprot_sec
O43528
resolver
uniprot_sec
Q5JXL5
resolver
uniprot_sec
Q9BRC1
resolver
amino_acid_sequence
MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN
uniprot
proteins
function
FUNCTION: Regulatory alpha-subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1 or KCNB2, can modulate their expression and their gating kinetics by acting on deactivation upon repolarization and inactivation during maintained depolarization (PubMed:19074135). Potassium channel subunit that does not form functional channels by itself (PubMed:19074135). {ECO:0000269|PubMed:19074135}.
uniprot
proteins
mass_dalton
57913
uniprot
proteins
protein_family
G (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv6.1/KCNG1 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19074135
uniprot
proteins
pubmed
9434767
uniprot
proteins
sequence_length
513
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q14721}; Multi-pass membrane protein {ECO:0000305}. Note=Colocalizes with KCNB1 at the plasma membrane. {ECO:0000250|UniProtKB:Q14721}.
uniprot
proteins
transmembrane_region
TRANSMEM 225..246; /note="Helical; Name=Segment S1"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 268..289; /note="Helical; Name=Segment S2"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 301..321; /note="Helical; Name=Segment S3"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 339..359; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 375..396; /note="Helical; Name=Segment S5"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 439..467; /note="Helical; Name=Segment S6"; /evidence="ECO:0000250|UniProtKB:P63142
uniprot
proteins