Cyp2a12
entrez
13085
canonical
uniprot
P56593
canonical
ensembl
ENSMUSG00000060407
resolver
ensp
ENSMUSP00000074990
resolver
enst
ENSMUST00000075552
resolver
genesymbol
Cyp2a12
resolver
uniprot
Q8VCW9
resolver
uniprot_entry
CP2AC_MOUSE
resolver
uniprot_sec
Q8VCW9
resolver
amino_acid_sequence
MLGSGLLLLAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNYLQLNRKDVYSSITQLQEHYGPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKGYGVAFSNGERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCLIKMLQGTCGAPIDPTIYLSKTASNVISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMKYLPGPQQQIIKDSHKLEDFMIQKVKQNQSTLDPNSPRDFIDSFLIHMQKEKYVNSEFHMKNLVMTSLNLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDKGQLKKIPAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNFRFKFPRKLEDINESPTPEGFTRIIPKYTMSFVPI
uniprot
proteins
ec_number
1.14.14.1
uniprot
proteins
function
FUNCTION: Highly active in the 7-alpha-hydroxylation of testosterone.
uniprot
proteins
mass_dalton
56179
uniprot
proteins
mutagenesis
MUTAGEN 206; /note="Q->G: Same as wild-type."; /evidence="ECO:0000269|PubMed:8484736"; MUTAGEN 208; /note="N->L: Stabilizes the protein, 17-fold lower Vmax."; /evidence="ECO:0000269|PubMed:8484736"; MUTAGEN 209; /note="K->Q: Same as wild-type."; /evidence="ECO:0000269|PubMed:8484736
uniprot
proteins
protein_family
Cytochrome P450 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8484736
uniprot
proteins
sequence_length
492
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
uniprot
proteins