TMPRSS11B
entrez
132724
canonical
uniprot
Q86T26
canonical
ensembl
ENSG00000185873
resolver
ensp
ENSP00000330475
resolver
enst
ENST00000332644
resolver
genesymbol
TMPRSS11B
resolver
genesymbol_syn
HATL5
resolver
hgnc
HGNC:25398
resolver
uniprot
A8K4D9
resolver
uniprot_entry
TM11B_HUMAN
resolver
uniprot_sec
A8K4D9
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by aprotinin, leupeptin, benzamidine, SERPINA1, SPINT1 and SPINT2. {ECO:0000269|PubMed:24498351}.
uniprot
proteins
amino_acid_sequence
MYRHGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHISGVTYNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFPPAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Serine protease. {ECO:0000269|PubMed:24498351}.
uniprot
proteins
mass_dalton
46337
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
24498351
uniprot
proteins
sequence_length
416
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24498351}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins