Fcrl1
entrez
229499
canonical
uniprot
Q8R4Y0
canonical
ensembl
ENSMUSG00000059994
resolver
ensp
ENSMUSP00000072300
resolver
ensp
ENSMUSP00000128235
resolver
ensp
ENSMUSP00000130936
resolver
ensp
ENSMUSP00000142286
resolver
ensp
ENSMUSP00000290039
resolver
enst
ENSMUST00000072480
resolver
enst
ENSMUST00000163661
resolver
enst
ENSMUST00000167200
resolver
enst
ENSMUST00000194786
resolver
genesymbol
Fcrl1
resolver
genesymbol_syn
Fcrh1
resolver
genesymbol_syn
Ifgp1
resolver
uniprot
A0A0A6YY56
resolver
uniprot
A0A0R4J0W8
resolver
uniprot
E9Q5S9
resolver
uniprot
E9Q958
resolver
uniprot
Q68SP0
resolver
uniprot
Q7TMH2
resolver
uniprot
Q80WN3
resolver
uniprot
Q8BYS4
resolver
uniprot_entry
A0A0A6YY56_MOUSE
resolver
uniprot_entry
A0A0R4J0W8_MOUSE
resolver
uniprot_entry
E9Q5S9_MOUSE
resolver
uniprot_entry
E9Q958_MOUSE
resolver
uniprot_entry
FCRL1_MOUSE
resolver
uniprot_sec
Q68SP0
resolver
uniprot_sec
Q7TMH2
resolver
uniprot_sec
Q80WN3
resolver
uniprot_sec
Q8BYS4
resolver
amino_acid_sequence
MLPWLLLLICALPCEPAGISDVSLKTRPPGGWVMEGDKLVLICSVDRVTGNITYFWYRGALGFQLETKTQPSLTAEFEISDMKQSDADQYYCAANDGHDPIASELVSIHVRVPVSRPVLTFGDSGTQAVLGDLVELHCKALRGSPPIFYQFYHESIILGNSSAPSGGGASFNFSLTAEHSGNFSCEASNGQGAQRSEVVALNLTGLSLVPTENGISHLSLGLTGWLLGCLSPITMALIFCYWLKRKIGRQSEDPVRSPPQTVLQGSTYPKSPDSRQPEPLYENVNVVSGNEVYSLVYHTPQVLEPAAAQHVRTHGVSESFQVSSGLYSKPRINIAHMDYEDAM
uniprot
proteins
function
FUNCTION: May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37277
uniprot
proteins
mutagenesis
MUTAGEN 281; /note="Y->F: Impaired BCR-mediated signaling and FCRL1-induced B-cell proliferation. Impaired phosphorylation."; /evidence="ECO:0000269|PubMed:31328160, ECO:0000269|PubMed:34697226"; MUTAGEN 297; /note="Y->F: Impaired phosphorylation."; /evidence="ECO:0000269|PubMed:34697226
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on C-terminal region upon BCR ligation leading to recruitment of ABL1 (PubMed:31328160). {ECO:0000269|PubMed:31328160}.
uniprot
proteins
pubmed
12037601
uniprot
proteins
pubmed
15302849
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
31328160
uniprot
proteins
pubmed
34697226
uniprot
proteins
sequence_length
343
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:31328160}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 220..240; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins