Ttll2
entrez
100216474
canonical
uniprot
A4Q9E4
canonical
ensembl
ENSMUSG00000079722
resolver
ensp
ENSMUSP00000111413
resolver
enst
ENSMUST00000115747
resolver
genesymbol
Ttll2
resolver
uniprot_entry
TTLL2_MOUSE
resolver
amino_acid_sequence
MDGLQSLGDVTAEIFGLPLEGHSVQESKPLKTEDEPQGAPLKPLVFRVDESTPGLVQSVLLERGWDKFDEQRQDVEDWNLYWRSSSFRRAEYVNVKPWQRLNHHPGMTNLTRKDCLAKHLARMRSRYGESLYEFTPLTFIMPTDYTKFVAKYFKEKQDLGTKPSYWICKPAELSRGRGIIIFSDIRDLMFKGTYVVQKYICNPLLVGRYKCDLRIYVCITGFKPLTIYMYQEGLVRFATEKFDLRNLEDYYSHLTNSSINKLGASYQKIKEVVGQGCKWTLSRFFSYLRNWDVDDLLLRQKISHMVILTVLAMAPSVPVTYNCFELFGFDILIDDNLKPWLLEVNYNPALTLDCSTDESVKRSLVHDVIELLYLNGLRSEEKKCGRTSPGNSVVSLARSHHHEFCATPNSSSYASLIEFTTGSKSDPAVQNICPKHTRTSQLREMMSRRDRLLTKEAAKSKPRHKAWHLPRKMVFPYASQSQPHKMKGPAGDLPEAGSTPNDHAGNFVLIFPFNKATFRASRNGLNVKRIIQELQKLMNK
uniprot
proteins
ec_number
6.-.-.-
uniprot
proteins
function
FUNCTION: Probable tubulin polyglutamylase that generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins (PubMed:17499049). Similar to TTLL1, may acquire enzymatic activity only in complex with other proteins as it is most likely lacking domains important for autonomous activity (By similarity). Probably involved in the side-chain initiation step of the polyglutamylation reaction rather than the elongation step (Probable). {ECO:0000250|UniProtKB:Q91V51, ECO:0000269|PubMed:17499049, ECO:0000305|Ref.2}.
uniprot
proteins
mass_dalton
62109
uniprot
proteins
protein_family
Tubulin--tyrosine ligase family
uniprot
proteins
pubmed
17499049
uniprot
proteins
sequence_length
540
uniprot
proteins