Ppie
entrez
56031
canonical
uniprot
Q9QZH3
canonical
ensembl
ENSMUSG00000028651
resolver
ensp
ENSMUSP00000030404
resolver
enst
ENSMUST00000030404
resolver
genesymbol
Ppie
resolver
genesymbol_syn
Cyp33
resolver
uniprot
Q9D8C0
resolver
uniprot_entry
PPIE_MOUSE
resolver
uniprot_sec
Q9D8C0
resolver
amino_acid_sequence
MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGPEPPKAEAQEGEPTAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPKQKVMIADCGEYM
uniprot
proteins
ec_number
5.2.1.8
uniprot
proteins
function
FUNCTION: Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity. {ECO:0000250|UniProtKB:Q9UNP9}.
uniprot
proteins
mass_dalton
33449
uniprot
proteins
protein_family
Cyclophilin-type PPIase family
uniprot
proteins
protein_family
PPIase E subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
301
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9UNP9}.
uniprot
proteins