SELENOO
entrez
83642
canonical
uniprot
Q9BVL4
canonical
ensembl
ENSG00000073169
resolver
ensp
ENSP00000370288
resolver
enst
ENST00000380903
resolver
genesymbol
SELENOO
resolver
genesymbol_syn
SELO
resolver
hgnc
HGNC:30395
resolver
uniprot
Q2TAL2
resolver
uniprot
Q5JZ81
resolver
uniprot
Q8WUI0
resolver
uniprot_entry
SELO_HUMAN
resolver
uniprot_sec
Q2TAL2
resolver
uniprot_sec
Q5JZ81
resolver
uniprot_sec
Q8WUI0
resolver
amino_acid_sequence
MAVYRAALGASLAAARLLPLGRCSPSPAPRSTLSGAAMEPAPRWLAGLRFDNRALRALPVEAPPPGPEGAPSAPRPVPGACFTRVQPTPLRQPRLVALSEPALALLGLGAPPAREAEAEAALFFSGNALLPGAEPAAHCYCGHQFGQFAGQLGDGAAMYLGEVCTATGERWELQLKGAGPTPFSRQADGRKVLRSSIREFLCSEAMFHLGVPTTRAGACVTSESTVVRDVFYDGNPKYEQCTVVLRVASTFIRFGSFEIFKSADEHTGRAGPSVGRNDIRVQLLDYVISSFYPEIQAAHASDSVQRNAAFFREVTRRTARMVAEWQCVGFCHGVLNTDNMSILGLTIDYGPFGFLDRYDPDHVCNASDNTGRYAYSKQPEVCRWNLRKLAEALQPELPLELGEAILAEEFDAEFQRHYLQKMRRKLGLVQVELEEDGALVSKLLETMHLTGADFTNTFYLLSSFPVELESPGLAEFLARLMEQCASLEELRLAFRPQMDPRQLSMMLMLAQSNPQLFALMGTRAGIARELERVEQQSRLEQLSAAELQSRNQGHWADWLQAYRARLDKDLEGAGDAAAWQAEHVRVMHANNPKYVLRNYIAQNAIEAAERGDFSEVRRVLKLLETPYHCEAGAATDAEATEADGADGRQRSYSSKPPLWAAELCVTUSS
uniprot
proteins
ec_number
2.7.7.-
uniprot
proteins
ec_number
2.7.7.108
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation) (PubMed:30270044). May be a redox-active mitochondrial selenoprotein which interacts with a redox target protein (PubMed:24751718). {ECO:0000269|PubMed:24751718, ECO:0000269|PubMed:30270044}.
uniprot
proteins
mass_dalton
73489
uniprot
proteins
mutagenesis
MUTAGEN 348; /note="D->A: Loss of catalytic activity. Loss of ATP binding."; /evidence="ECO:0000269|PubMed:30270044"; MUTAGEN 664..667; /note="CVTU->SVTC: Enhances redox complex formation."; /evidence="ECO:0000269|PubMed:24751718"; MUTAGEN 664..667; /note="CVTU->SVTS: Abolishes redox complex formation."; /evidence="ECO:0000269|PubMed:24751718"; MUTAGEN 664; /note="C->S: No effect on redox complex formation."; /evidence="ECO:0000269|PubMed:24751718"; MUTAGEN 667; /note="U->C: Slightly enhances redox complex formation."; /evidence="ECO:0000269|PubMed:24751718"; MUTAGEN 667; /note="U->S: No effect on redox complex formation."; /evidence="ECO:0000269|PubMed:24751718
uniprot
proteins
protein_family
SELO family
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
12775843
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24751718
uniprot
proteins
pubmed
27645994
uniprot
proteins
pubmed
30270044
uniprot
proteins
sequence_length
669
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:24751718}.
uniprot
proteins