Acot12
entrez
74156
canonical
uniprot
Q9DBK0
canonical
ensembl
ENSMUSG00000021620
resolver
ensp
ENSMUSP00000022120
resolver
ensp
ENSMUSP00000303759
resolver
enst
ENSMUST00000022120
resolver
genesymbol
Acot12
resolver
genesymbol_syn
Cach
resolver
genesymbol_syn
Cach1
resolver
uniprot
A2RSC2
resolver
uniprot
Q544M5
resolver
uniprot
Q8R108
resolver
uniprot_entry
A2RSC2_MOUSE
resolver
uniprot_entry
ACO12_MOUSE
resolver
uniprot_sec
Q544M5
resolver
uniprot_sec
Q8R108
resolver
activity_regulation
ACTIVITY REGULATION: Allosterically regulated by ATP (activator) and ADP (inhibitor) (By similarity). Cold labile, it dissociates into inactive monomers at low temperature (By similarity). {ECO:0000250|UniProtKB:Q8WYK0, ECO:0000250|UniProtKB:Q99NB7}.
uniprot
proteins
amino_acid_sequence
MESMVAPGEVLMSQAIQPAHADSRGELSAGQLLKWMDTTACLAAEKHAGISCVTASMDDILFEDTARIGQIITIRAKVTRAFSTSMEISIKVIVQDKFTGIQKLLCVAFSTFVAKPVGKEKVHLKPVLLQTEQEQVEHNLASERRKVRLQHENTFNNIMKESSRFSDSICNEEEGTATTMGTSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCHGHPFLKSVDMFKFRGPSTVGDRLVFSAIVNNTFQNSVEVGVRVEAFDCQEWAEGQGRHINSAFLIYNAVDDQEKLITFPRIQPISKDDFRRYQGAIARRRIRLGRKYVISHKKEVPLSAQWDISKKGSLSNTNVEALKNLASKSGWEITTTLEKIKIYTLEEQDAISVKVEKLVGSPAHIAYHLLSDLTKRPLWDPHYISCEVIDQVSEDDQIYYITCSVVNGDKPKDFVVLVSRRKPLKDNNTYTVALRSVVLPSVPSSPQYIRSEVICAGFLIQAVDSNSCTVTYLNQMSDSILPYFAGNIGGWSKSIEEAAASCIKFIENATPDGLKSVL
uniprot
proteins
ec_number
3.1.2.1
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes acetyl-CoA. {ECO:0000250|UniProtKB:Q8WYK0}.
uniprot
proteins
mass_dalton
61762
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid metabolism. {ECO:0000250|UniProtKB:Q8WYK0}.
uniprot
proteins
pubmed
12545200
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
556
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8WYK0}.
uniprot
proteins