HTR3D
entrez
200909
canonical
uniprot
Q70Z44
canonical
ensembl
ENSG00000186090
resolver
ensp
ENSP00000334315
resolver
ensp
ENSP00000371929
resolver
ensp
ENSP00000389268
resolver
ensp
ENSP00000405409
resolver
enst
ENST00000334128
resolver
genesymbol
HTR3D
resolver
hgnc
HGNC:24004
resolver
uniprot
C9J2I6
resolver
uniprot
F6WC43
resolver
uniprot
J3QT78
resolver
uniprot
Q495N5
resolver
uniprot
Q495N6
resolver
uniprot
Q7Z6B3
resolver
uniprot_entry
5HT3D_HUMAN
resolver
uniprot_entry
F6WC43_HUMAN
resolver
uniprot_sec
C9J2I6
resolver
uniprot_sec
J3QT78
resolver
uniprot_sec
Q495N5
resolver
uniprot_sec
Q495N6
resolver
uniprot_sec
Q7Z6B3
resolver
amino_acid_sequence
MQKHSPGPPALALLSQSLLTTGNGDTLIINCPGFGQHRVDPAAFQAVFDRKAIGPVTNYSVATHVNISFTLSAIWNCYSRIHTFNCHHARPWHNQFVQWNPDECGGIKKSGMATENLWLSDVFIEESVDQTPAGLMASMSIVKATSNTISQCGWSASANWTPSISPSMDRARAWRRMSRSFQIHHRTSFRTRREWVLLGIQKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVAPLALMQTPLPAGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTGGSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVICLWNT
uniprot
proteins
function
FUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. {ECO:0000269|PubMed:17392525}.
uniprot
proteins
mass_dalton
50191
uniprot
proteins
protein_family
5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily
uniprot
proteins
protein_family
HTR3D sub-subfamily
uniprot
proteins
protein_family
Ligand-gated ion channel (TC 1.A.9) family
uniprot
proteins
pubmed
12801637
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17392525
uniprot
proteins
sequence_length
454
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Postsynaptic cell membrane {ECO:0000305|PubMed:17392525}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:17392525}; Multi-pass membrane protein {ECO:0000255}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. {ECO:0000269|PubMed:17392525}.
uniprot
proteins
transmembrane_region
TRANSMEM 233..253; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 265..285; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 307..327; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 432..452; /note="Helical; Name=4"; /evidence="ECO:0000255
uniprot
proteins