CCNB1IP1
entrez
57820
canonical
uniprot
Q9NPC3
canonical
ensembl
ENSG00000100814
resolver
ensembl
ENSG00000291784
resolver
ensp
ENSP00000337396
resolver
ensp
ENSP00000351810
resolver
ensp
ENSP00000381226
resolver
ensp
ENSP00000381229
resolver
ensp
ENSP00000381235
resolver
ensp
ENSP00000517311
resolver
ensp
ENSP00000517312
resolver
ensp
ENSP00000517313
resolver
ensp
ENSP00000517314
resolver
ensp
ENSP00000517315
resolver
ensp
ENSP00000517316
resolver
ensp
ENSP00000563267
resolver
ensp
ENSP00000563268
resolver
ensp
ENSP00000563269
resolver
ensp
ENSP00000563270
resolver
ensp
ENSP00000563271
resolver
ensp
ENSP00000563272
resolver
ensp
ENSP00000563273
resolver
ensp
ENSP00000601499
resolver
ensp
ENSP00000601500
resolver
ensp
ENSP00000601501
resolver
ensp
ENSP00000601502
resolver
ensp
ENSP00000601503
resolver
ensp
ENSP00000601504
resolver
ensp
ENSP00000601505
resolver
ensp
ENSP00000601506
resolver
ensp
ENSP00000601507
resolver
ensp
ENSP00000601508
resolver
ensp
ENSP00000601509
resolver
ensp
ENSP00000601510
resolver
ensp
ENSP00000601511
resolver
ensp
ENSP00000601512
resolver
ensp
ENSP00000601513
resolver
ensp
ENSP00000601514
resolver
ensp
ENSP00000601515
resolver
ensp
ENSP00000601516
resolver
ensp
ENSP00000601517
resolver
ensp
ENSP00000601518
resolver
ensp
ENSP00000617455
resolver
ensp
ENSP00000617456
resolver
enst
ENST00000353689
resolver
enst
ENST00000358932
resolver
enst
ENST00000398160
resolver
enst
ENST00000398163
resolver
enst
ENST00000398169
resolver
enst
ENST00000708737
resolver
enst
ENST00000708738
resolver
enst
ENST00000708739
resolver
enst
ENST00000708740
resolver
enst
ENST00000708741
resolver
enst
ENST00000708742
resolver
enst
ENST00000893208
resolver
enst
ENST00000893209
resolver
enst
ENST00000893210
resolver
enst
ENST00000893211
resolver
enst
ENST00000893212
resolver
enst
ENST00000893213
resolver
enst
ENST00000893214
resolver
enst
ENST00000931440
resolver
enst
ENST00000931441
resolver
enst
ENST00000931442
resolver
enst
ENST00000931443
resolver
enst
ENST00000931444
resolver
enst
ENST00000931445
resolver
enst
ENST00000931446
resolver
enst
ENST00000931447
resolver
enst
ENST00000931448
resolver
enst
ENST00000931449
resolver
enst
ENST00000931450
resolver
enst
ENST00000931451
resolver
enst
ENST00000931452
resolver
enst
ENST00000931453
resolver
enst
ENST00000931454
resolver
enst
ENST00000931455
resolver
enst
ENST00000931456
resolver
enst
ENST00000931457
resolver
enst
ENST00000931458
resolver
enst
ENST00000931459
resolver
enst
ENST00000947396
resolver
enst
ENST00000947397
resolver
genesymbol
CCNB1IP1
resolver
genesymbol_syn
C14orf18
resolver
genesymbol_syn
HEI10
resolver
hgnc
HGNC:19437
resolver
uniprot
A0A384MR52
resolver
uniprot_entry
A0A384MR52_HUMAN
resolver
uniprot_entry
CIP1_HUMAN
resolver
amino_acid_sequence
MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQMEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFAGSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. {ECO:0000250, ECO:0000269|PubMed:12612082, ECO:0000269|PubMed:17297447}.
uniprot
proteins
mass_dalton
31544
uniprot
proteins
mutagenesis
MUTAGEN 28; /note="C->A: Abrogates induction of filamentous growth in yeast; when associated with A-30 and A-33."; /evidence="ECO:0000269|PubMed:12612082"; MUTAGEN 30; /note="H->A: Abrogates induction of filamentous growth in yeast; when associated with A-28 and A-33."; /evidence="ECO:0000269|PubMed:12612082"; MUTAGEN 33; /note="C->A: Abrogates induction of filamentous growth in yeast; when associated with A-28 and A-30."; /evidence="ECO:0000269|PubMed:12612082
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated; autoubiquitinated. {ECO:0000269|PubMed:12612082}.; PTM: Phosphorylated by CDK1 on serine or threonine residues (in vitro). {ECO:0000269|PubMed:12612082}.
uniprot
proteins
pubmed
12612082
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16532029
uniprot
proteins
pubmed
17297447
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
277
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Chromosome. Note=Associates to the synaptonemal complex.
uniprot
proteins