Cnih2
entrez
12794
canonical
uniprot
O35089
canonical
ensembl
ENSMUSG00000024873
resolver
ensp
ENSMUSP00000025805
resolver
enst
ENSMUST00000025805
resolver
genesymbol
Cnih2
resolver
genesymbol_syn
Cnil
resolver
uniprot
Q3SYI8
resolver
uniprot_entry
CNIH2_MOUSE
resolver
uniprot_entry
Q3SYI8_MOUSE
resolver
amino_acid_sequence
MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF
uniprot
proteins
function
FUNCTION: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. {ECO:0000269|PubMed:20805473, ECO:0000269|PubMed:21172611}.
uniprot
proteins
mass_dalton
18931
uniprot
proteins
protein_family
Cornichon family
uniprot
proteins
pubmed
10022955
uniprot
proteins
pubmed
20805473
uniprot
proteins
pubmed
21172611
uniprot
proteins
pubmed
33981040
uniprot
proteins
sequence_length
160
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Postsynaptic density {ECO:0000269|PubMed:21172611}. Cell projection, dendrite {ECO:0000269|PubMed:21172611}. Cell projection, dendritic spine {ECO:0000269|PubMed:21172611}. Postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..159; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins