Gfer
entrez
27100
canonical
uniprot
Q63042
canonical
ensembl
ENSRNOG00000013370
resolver
ensp
ENSRNOP00000017917
resolver
genesymbol
Gfer
resolver
genesymbol_syn
Alr
resolver
uniprot_entry
ALR_RAT
resolver
amino_acid_sequence
MAAPSEPAGFPRGSRFSFLPGGAHSEMTDDLVTDARGRGARHRKDNAPAAAPAPKGLEHGKRPCRACVDFKSWMRTQQKRDIKFREDCPQDREELGRNTWAFLHTLAAYYPDMPTPEQQQDMAQFIHIFSKFYPCEECAEDIRKRIDRSQPDTSTRVSFSQWLCRLHNEVNRKLGKPDFDCSRVDERWRDGWKDGSCD
uniprot
proteins
ec_number
1.8.3.2
uniprot
proteins
function
FUNCTION: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. May have a function in liver regeneration and spermatogenesis. {ECO:0000269|PubMed:8058770}.
uniprot
proteins
mass_dalton
22837
uniprot
proteins
pubmed
12717032
uniprot
proteins
pubmed
12906155
uniprot
proteins
pubmed
22948913
uniprot
proteins
pubmed
7708779
uniprot
proteins
pubmed
8058770
uniprot
proteins
sequence_length
198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:P55789}. Mitochondrion {ECO:0000250|UniProtKB:P55789}.
uniprot
proteins