Drc3
entrez
74665
canonical
uniprot
Q9D5E4
canonical
ensembl
ENSMUSG00000056598
resolver
ensp
ENSMUSP00000104363
resolver
ensp
ENSMUSP00000255898
resolver
enst
ENSMUST00000108723
resolver
genesymbol
Drc3
resolver
genesymbol_syn
Lrrc48
resolver
uniprot_entry
DRC3_MOUSE
resolver
amino_acid_sequence
MSRPYDSMEPKVMDDDMLKAAVGEQGPQEEAGQLAKQEGILFKDVLSLQLDFQNILRIDNLWQFENLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVKLQVLSLGNNQISNMMNIIYLRRFPCLRTLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFRRVDEQMREMAKMKHQYSIDELKHREAQLQMKLEEEQAKQEKLEEHKMAFVEHLNGPFLFDSMYSEDVEGNKLSYLPGVRELLEAYKDKFVIICLNIFEYGLNQQEKRKVELDTFNECIQEAILENQDQGKLKVAKFEEKHLLNLNAIREETDLSNIEKKLTECTESIGELFNTLMILEMQLVEQLEETINIFERNITDLVGLFIENVQSLIAQCRDLENHHHEKLLEIAINTLEKILKGEMDEDLPDDVRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTGINSWCAHLVDKIHKDEIMRNRKRVKEINQFVDHMQSELDNLECGDIID
uniprot
proteins
function
FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. {ECO:0000250|UniProtKB:A8IVX2}.
uniprot
proteins
mass_dalton
60827
uniprot
proteins
protein_family
DRC3 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28630322
uniprot
proteins
pubmed
31961863
uniprot
proteins
pubmed
39092789
uniprot
proteins
sequence_length
523
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9H069}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9H069}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:39092789}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:31961863}.
uniprot
proteins