Hesx1
entrez
15209
canonical
uniprot
Q61658
canonical
ensembl
ENSMUSG00000040726
resolver
ensp
ENSMUSP00000041999
resolver
ensp
ENSMUSP00000152952
resolver
ensp
ENSMUSP00000334111
resolver
enst
ENSMUST00000035433
resolver
enst
ENSMUST00000224331
resolver
genesymbol
Hesx1
resolver
genesymbol_syn
Hes-1
resolver
genesymbol_syn
Rpx
resolver
uniprot
Q61047
resolver
uniprot
Q8C477
resolver
uniprot_entry
HESX1_MOUSE
resolver
uniprot_sec
Q61047
resolver
uniprot_sec
Q8C477
resolver
amino_acid_sequence
MSPSLREGAQLRESKPAPCSFSIESILGLDQKKDCTTSVRPHRPWTDTCGDSEKGGNPPLHAPDLPSETSFPCPVDHPRPEERAPKYENYFSASETRSLKRELSWYRGRRPRTAFTQNQVEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKMKRSRRESQFLMAKKPFNPDLLK
uniprot
proteins
function
FUNCTION: Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation. {ECO:0000269|PubMed:9620767}.
uniprot
proteins
mass_dalton
21504
uniprot
proteins
protein_family
ANF homeobox family
uniprot
proteins
pubmed
1360650
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
7876132
uniprot
proteins
pubmed
8565852
uniprot
proteins
pubmed
9620767
uniprot
proteins
sequence_length
185
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins