Ctbp1
entrez
29382
canonical
uniprot
Q9Z2F5
canonical
ensembl
ENSRNOG00000005428
resolver
ensp
ENSRNOP00000054738
resolver
ensp
ENSRNOP00000080240
resolver
ensp
ENSRNOP00000081185
resolver
enst
ENSRNOT00000057929
resolver
enst
ENSRNOT00000119292
resolver
genesymbol
Ctbp1
resolver
genesymbol_syn
Bars
resolver
genesymbol_syn
Ctbp3
resolver
uniprot
A0A8I5ZSG1
resolver
uniprot
F7FG31
resolver
uniprot
Q6AZ26
resolver
uniprot_entry
A0A8I5ZSG1_RAT
resolver
uniprot_entry
CTBP1_RAT
resolver
uniprot_entry
F7FG31_RAT
resolver
uniprot_entry
Q6AZ26_RAT
resolver
amino_acid_sequence
MSGVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGAAYSRYPPGVVSVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHTTDQL
uniprot
proteins
ec_number
1.1.1.-
uniprot
proteins
function
FUNCTION: Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. {ECO:0000269|PubMed:10364211, ECO:0000269|PubMed:12805226, ECO:0000269|PubMed:7624370}.
uniprot
proteins
mass_dalton
46628
uniprot
proteins
mutagenesis
MUTAGEN 41; /note="A->E: Strongly reduces interaction with E1A."; /evidence="ECO:0000269|PubMed:12805226"; MUTAGEN 55; /note="V->R: Strongly reduces interaction with E1A."; /evidence="ECO:0000269|PubMed:12805226"; MUTAGEN 172; /note="G->E: Loss dimerization and of NAD binding."; /evidence="ECO:0000269|PubMed:19351597
uniprot
proteins
post_translational_modification
PTM: The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-412 induces proteasomal degradation (By similarity). {ECO:0000250}.; PTM: ADP-ribosylated; when cells are exposed to brefeldin A.; PTM: Sumoylation on Lys-418 is promoted by the E3 SUMO-protein ligase CBX4. {ECO:0000250}.
uniprot
proteins
protein_family
D-isomer specific 2-hydroxyacid dehydrogenase family
uniprot
proteins
pubmed
10364211
uniprot
proteins
pubmed
12805226
uniprot
proteins
pubmed
16940172
uniprot
proteins
pubmed
19351597
uniprot
proteins
pubmed
25652077
uniprot
proteins
pubmed
7624370
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q13363}. Nucleus {ECO:0000269|PubMed:25652077}. Synapse, synaptosome {ECO:0000269|PubMed:25652077}.
uniprot
proteins