MZT2A
entrez
653784
canonical
uniprot
Q6P582
canonical
ensembl
ENSG00000173272
resolver
ensp
ENSP00000311500
resolver
ensp
ENSP00000403353
resolver
ensp
ENSP00000556613
resolver
ensp
ENSP00000775316
resolver
enst
ENST00000309451
resolver
genesymbol
MZT2A
resolver
genesymbol_syn
FAM128A
resolver
genesymbol_syn
MOZART2A
resolver
hgnc
HGNC:33187
resolver
uniprot
Q3SWV8
resolver
uniprot
Q8WVB2
resolver
uniprot_entry
MZT2A_HUMAN
resolver
uniprot_sec
Q3SWV8
resolver
uniprot_sec
Q8WVB2
resolver
amino_acid_sequence
MAAQGVGPGPGSAAPPGLEAARQKLALRRKKVLSTEEMELYELAQAAGGGIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQDPAAVSLPTSSVPETRGRDKGSAALGGVLALAERSNHEGSSQRMPRQPSATRLPKGGGPGKSPTQGST
uniprot
proteins
function
FUNCTION: Required for the recruitment and the assembly of the gamma-tubulin ring complex (gTuRC) at the centrosome (PubMed:20360068, PubMed:39321809). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed:39321809). {ECO:0000269|PubMed:20360068, ECO:0000269|PubMed:39321809}.
uniprot
proteins
mass_dalton
16221
uniprot
proteins
protein_family
MOZART2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
20360068
uniprot
proteins
pubmed
39321809
uniprot
proteins
sequence_length
158
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q6NZ67}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q6NZ67}.
uniprot
proteins