Cd59a
entrez
12509
canonical
uniprot
O55186
canonical
ensembl
ENSMUSG00000032679
resolver
ensp
ENSMUSP00000048041
resolver
ensp
ENSMUSP00000132774
resolver
ensp
ENSMUSP00000332740
resolver
ensp
ENSMUSP00000332744
resolver
ensp
ENSMUSP00000332746
resolver
enst
ENSMUST00000040423
resolver
enst
ENSMUST00000168176
resolver
genesymbol
Cd59a
resolver
genesymbol_syn
Cd59
resolver
uniprot
A2BI31
resolver
uniprot
Q542R7
resolver
uniprot_entry
A2BI31_MOUSE
resolver
uniprot_entry
CD59A_MOUSE
resolver
uniprot_sec
Q542R7
resolver
amino_acid_sequence
MRAQRGLILLLLLLAVFCSTAVSLTCYHCFQPVVSSCNMNSTCSPDQDSCLYAVAGMQVYQRCWKQSDCHGEIIMDQLEETKLKFRCCQFNLCNKSDGSLGKTPLLGTSVLVAILNLCFLSHL
uniprot
proteins
function
FUNCTION: Potent inhibitor of the complement membrane attack complex (MAC) action, which protects self-cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins
mass_dalton
13648
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins
pubmed
10965140
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
9029105
uniprot
proteins
sequence_length
123
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P13987}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:P13987}. Secreted {ECO:0000250|UniProtKB:P13987}. Note=Localizes to the cell surface. Soluble form found in a number of tissues. {ECO:0000250|UniProtKB:P13987}.
uniprot
proteins