CSNK1G1
entrez
53944
canonical
uniprot
Q9HCP0
canonical
ensembl
ENSG00000169118
resolver
ensp
ENSP00000305777
resolver
ensp
ENSP00000475724
resolver
ensp
ENSP00000476088
resolver
ensp
ENSP00000557642
resolver
enst
ENST00000561349
resolver
enst
ENST00000607537
resolver
genesymbol
CSNK1G1
resolver
hgnc
HGNC:2454
resolver
uniprot
A0ACM8PXG0
resolver
uniprot
Q5JPH1
resolver
uniprot
Q8IXA3
resolver
uniprot
Q96AE9
resolver
uniprot
Q9HCP1
resolver
uniprot
U3KQB3
resolver
uniprot
U3KQN9
resolver
uniprot_entry
A0ACM8PXG0_HUMAN
resolver
uniprot_entry
KC1G1_HUMAN
resolver
uniprot_entry
Q8IXA3_HUMAN
resolver
uniprot_entry
U3KQB3_HUMAN
resolver
uniprot_sec
Q5JPH1
resolver
uniprot_sec
Q96AE9
resolver
uniprot_sec
Q9HCP1
resolver
uniprot_sec
U3KQN9
resolver
activity_regulation
ACTIVITY REGULATION: Repressed by 2-(2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine (DB08325).
uniprot
proteins
amino_acid_sequence
MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRPSQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQRHK
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN. {ECO:0000250, ECO:0000269|PubMed:21680713}.
uniprot
proteins
mass_dalton
48511
uniprot
proteins
mutagenesis
MUTAGEN 169; /note="N->A: Loss of kinase activity."; /evidence="ECO:0000269|PubMed:21680713
uniprot
proteins
post_translational_modification
PTM: Autophosphorylated. {ECO:0000250}.
uniprot
proteins
protein_family
CK1 Ser/Thr protein kinase family
uniprot
proteins
protein_family
Casein kinase I subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
11124537
uniprot
proteins
pubmed
14759258
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17344846
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
21680713
uniprot
proteins
pubmed
24463883
uniprot
proteins
sequence_length
422
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins