D3ZRP6
uniprot
D3ZRP6
canonical
amino_acid_sequence
MSASAVFILDVKGKPLISRNYKGDVPMTEIDHFMPLLMQREEEGMLAPLLSHGRVHFLWIKHSNLYLVATTLKNANASLVYSFLYKTVEVFCEYFKELEEESIRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQQGNKLETGKSRVPPTVTNAVSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTGRSKNKSVELEDVKFHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVRPRVDXESVIEKFSHSRVEIMVKAKGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPEKNVVIWSIKSFPGGKEYLMRAHFGLPSVETEEVEGRPPIGVKFEIPYFTVSGIQVRYMKIIEKSGYQALPWVRYITQSGDYQLRTS
uniprot
proteins
function
FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. {ECO:0000250|UniProtKB:Q9Y6Q5}.
uniprot
proteins
mass_dalton
48167
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. {ECO:0000250}.
uniprot
proteins
protein_family
Adaptor complexes medium subunit family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15985462
uniprot
proteins
sequence_length
423
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q9Y6Q5}. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:Q9Y6Q5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9Y6Q5}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9Y6Q5}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250|UniProtKB:Q9Y6Q5}.
uniprot
proteins