Kcnv1
entrez
67498
canonical
uniprot
Q8BZN2
canonical
ensembl
ENSMUSG00000022342
resolver
ensp
ENSMUSP00000022967
resolver
enst
ENSMUST00000022967
resolver
genesymbol
Kcnv1
resolver
uniprot
Q8BK61
resolver
uniprot
Q8BYS7
resolver
uniprot
Q9CZR1
resolver
uniprot_entry
KCNV1_MOUSE
resolver
uniprot_sec
Q8BK61
resolver
uniprot_sec
Q8BYS7
resolver
uniprot_sec
Q9CZR1
resolver
amino_acid_sequence
MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSKGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNLQLLEILEYVCISWFTGEFVLRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF
uniprot
proteins
function
FUNCTION: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
56669
uniprot
proteins
protein_family
Kv8.1/KCNV1 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
protein_family
V (TC 1.A.1.2) subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
503
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2 (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 214..234; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 242..262; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 280..300; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 313..334; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 349..369; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 410..430; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins