Enpp4
entrez
224794
canonical
uniprot
Q8BTJ4
canonical
ensembl
ENSMUSG00000023961
resolver
ensp
ENSMUSP00000024757
resolver
ensp
ENSMUSP00000114429
resolver
ensp
ENSMUSP00000304316
resolver
ensp
ENSMUSP00000304320
resolver
genesymbol
Enpp4
resolver
genesymbol_syn
Kiaa0879
resolver
uniprot
Q3TZS2
resolver
uniprot
Q69ZX0
resolver
uniprot
Q8K1L3
resolver
uniprot_entry
ENPP4_MOUSE
resolver
uniprot_sec
Q3TZS2
resolver
uniprot_sec
Q69ZX0
resolver
uniprot_sec
Q8K1L3
resolver
amino_acid_sequence
MFNMKILVIPLFWGLVTGYKGNSSDSSAPRLLLVSFDGFRADYLKSYDLPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDSVTKKHFSESNDKDPFWWNGAEPIWVTNQLQENRSSAAAMWPGTDVPIHNITASYFMNYSSSVSFKERLGNVTTWLSSSNPPVTFAALYWEEPDVSGHKYGPEDKENMRRVLKEVDDLIGDIVLKLKVLGLWDSLNVIITSDHGMAQCSKNRLIDLDSCIDRSNYSVIDLTPVAAILPKINVTEVYDKLKRCNPHMNVYLKEAIPNRFYYQHSSRIQPIILVAEEGWTITLNKSSFKLGDHGYDNSLPSMHPFLAAHGPAFRKGYRQSTINTVDIYPMMCHILGLKPHPNNGTLSHTKCLLVDQWCINLPEAIGIVVSALLVLTMLTGLMIFMRSRASTSRPFSRLQLQEDDDDPLID
uniprot
proteins
ec_number
3.6.1.29
uniprot
proteins
function
FUNCTION: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
51611
uniprot
proteins
protein_family
Nucleotide pyrophosphatase/phosphodiesterase family
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
456
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 411..431; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins