Lzts3
entrez
280670
canonical
uniprot
Q8K1Q4
canonical
ensembl
ENSRNOG00000021231
resolver
ensp
ENSRNOP00000084706
resolver
ensp
ENSRNOP00000110375
resolver
enst
ENSRNOT00000101454
resolver
enst
ENSRNOT00000150128
resolver
genesymbol
Lzts3
resolver
genesymbol_syn
Prosapip1
resolver
uniprot
A0A8I5ZYI8
resolver
uniprot
A0ABK0LVQ7
resolver
uniprot_entry
A0A8I5ZYI8_RAT
resolver
uniprot_entry
A0ABK0LVQ7_RAT
resolver
uniprot_entry
LZTS3_RAT
resolver
amino_acid_sequence
MAPADLASEGPKLEDPPAPHLFGKCPSGLIMANVETLPVRADPGRDPLLAFAPRPAELGPPDPRLTMGSVGGGVTHAQEFPMKSVGTRTGGGGSQGSFPGPRSSGSGTNRERPGPGRYPSEDKVLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPNHPPKLLTTSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPAGLKGGLEKSRTMTPAGGSGGGGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTPGYSSGGGGGGSGYQDLGTSDSGRASSKSGSSSSMGRSGHLGSGEGGNGGLPFAACSPPSPSALIQELEERLWEKEQEVAALRRSQEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAAQLIRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFGSKQASLELSEGELPPACLKPALTPVDLVEPQEALASCESDEAKMRRQAGVAAAASLVSVDGEVDAGGEGGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGSRTPTPQHGEEEKAWTPSRLERIESTEI
uniprot
proteins
function
FUNCTION: May be involved in promoting the maturation of dendritic spines, probably via regulating SIPA1L1 levels at the postsynaptic density of synapses (PubMed:27252646). {ECO:0000269|PubMed:27252646}.
uniprot
proteins
mass_dalton
75179
uniprot
proteins
mutagenesis
MUTAGEN 700; /note="S->G,S: Abolishes interaction with SHANK3."; /evidence="ECO:0000269|PubMed:16522626"; MUTAGEN 701; /note="T->A,S: Abolishes interaction with SHANK3."; /evidence="ECO:0000269|PubMed:16522626"; MUTAGEN 703; /note="I->A,G,V: Abolishes interaction with SHANK3."; /evidence="ECO:0000269|PubMed:16522626
uniprot
proteins
protein_family
LZTS3 family
uniprot
proteins
pubmed
16522626
uniprot
proteins
pubmed
27252646
uniprot
proteins
sequence_length
703
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Synapse {ECO:0000269|PubMed:27252646}. Postsynaptic density {ECO:0000269|PubMed:16522626, ECO:0000269|PubMed:27252646}. Cell projection, dendritic spine {ECO:0000269|PubMed:16522626}. Cell projection, dendrite {ECO:0000269|PubMed:16522626}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16522626}. Note=Rather found at excitatory than inhibitory synapses (PubMed:27252646). {ECO:0000269|PubMed:16522626, ECO:0000269|PubMed:27252646}.
uniprot
proteins