EMR3
entrez
84658
canonical
uniprot
Q9BY15
canonical
ensembl
ENSG00000131355
resolver
ensp
ENSP00000253673
resolver
ensp
ENSP00000340758
resolver
ensp
ENSP00000396208
resolver
ensp
ENSP00000631315
resolver
enst
ENST00000443157
resolver
genesymbol
ADGRE3
resolver
genesymbol
EMR3
resolver
genesymbol_syn
EMR3
resolver
hgnc
HGNC:23647
resolver
uniprot
A1L1B9
resolver
uniprot
B7Z5A1
resolver
uniprot
E7EW83
resolver
uniprot
Q0IJ53
resolver
uniprot_entry
A1L1B9_HUMAN
resolver
uniprot_entry
AGRE3_HUMAN
resolver
uniprot_entry
B7Z5A1_HUMAN
resolver
uniprot_entry
E7EW83_HUMAN
resolver
uniprot_entry
Q0IJ53_HUMAN
resolver
amino_acid_sequence
MQGPLLLPGLCFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEGRKELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILRDVESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMDIRCSDIIQGDTQGPSAIAFISYSSLGNIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPGQVKRKY
uniprot
proteins
function
FUNCTION: Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils. {ECO:0000269|PubMed:11279179}.
uniprot
proteins
mass_dalton
72621
uniprot
proteins
post_translational_modification
PTM: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. {ECO:0000250|UniProtKB:Q9UHX3}.
uniprot
proteins
protein_family
Adhesion G protein-coupled receptor (ADGR) subfamily
uniprot
proteins
protein_family
G protein-coupled receptor 2 family
uniprot
proteins
pubmed
11279179
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
25713288
uniprot
proteins
sequence_length
652
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
uniprot
proteins
transmembrane_region
TRANSMEM 358..378; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 390..410; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 417..437; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 465..485; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 509..529; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 558..578; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 581..601; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins