NMRK2
entrez
27231
canonical
uniprot
Q9NPI5
canonical
ensembl
ENSG00000077009
resolver
ensp
ENSP00000168977
resolver
ensp
ENSP00000480091
resolver
ensp
ENSP00000531872
resolver
ensp
ENSP00000583607
resolver
ensp
ENSP00000764988
resolver
ensp
ENSP00000764996
resolver
genesymbol
NMRK2
resolver
genesymbol_syn
ITGB1BP3
resolver
genesymbol_syn
NRK2
resolver
hgnc
HGNC:17871
resolver
uniprot
B7ZKR3
resolver
uniprot
Q52M81
resolver
uniprot
Q9NZK3
resolver
uniprot_entry
NRK2_HUMAN
resolver
uniprot_sec
B7ZKR3
resolver
uniprot_sec
Q52M81
resolver
uniprot_sec
Q9NZK3
resolver
amino_acid_sequence
MKLIVGIGGMTNGGKTTLTNSLLRALPNCCVIHQDDFFKPQDQIAVGEDGFKQWDVLESLDMEAMLDTVQAWLSSPQKFARAHGVSVQPEASDTHILLLEGFLLYSYKPLVDLYSRRYFLTVPYEECKWRRSTRNYTVPDPPGLFDGHVWPMYQKYRQEMEANGVEVVYLDGMKSREELFREVLEDIQNSLLNRSQESAPSPARPARTQGPGRGCGHRTARPAASQQDSM
uniprot
proteins
ec_number
2.7.1.173
uniprot
proteins
ec_number
2.7.1.22
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis. {ECO:0000269|PubMed:10613898, ECO:0000269|PubMed:15137942}.
uniprot
proteins
mass_dalton
26046
uniprot
proteins
mutagenesis
MUTAGEN 35; /note="D->A: Loss of activity."; /evidence="ECO:0000269|PubMed:17914902"; MUTAGEN 100; /note="E->A: Loss of activity."; /evidence="ECO:0000269|PubMed:17914902
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis. {ECO:0000305|PubMed:17914902}.
uniprot
proteins
protein_family
NRK subfamily
uniprot
proteins
protein_family
Uridine kinase family
uniprot
proteins
pubmed
10613898
uniprot
proteins
pubmed
12941630
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15137942
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17914902
uniprot
proteins
sequence_length
230
uniprot
proteins