Pigw
entrez
70325
canonical
uniprot
Q8C398
canonical
ensembl
ENSMUSG00000045140
resolver
ensp
ENSMUSP00000064547
resolver
ensp
ENSMUSP00000103715
resolver
ensp
ENSMUSP00000243519
resolver
enst
ENSMUST00000067058
resolver
enst
ENSMUST00000108080
resolver
genesymbol
Pigw
resolver
uniprot
B7ZN11
resolver
uniprot
Q8C4S0
resolver
uniprot
Q9CSX1
resolver
uniprot_entry
B7ZN11_MOUSE
resolver
uniprot_entry
PIGW_MOUSE
resolver
uniprot_sec
Q8C4S0
resolver
uniprot_sec
Q9CSX1
resolver
amino_acid_sequence
MSQKQLKEAFVRNLSGTSVLEVTQGLCFPAFCILCRGLWIIFSQHVCSFSNTWSTRFLMDFVVLIVPLVITLTVLSSFILLENLTVIVWGAWLLYQIYHRRTCYAKVPVQKVFANFLKISLESEYNPAITCYRVINSVFTAIAILAVDFPLFPRRFAKTELYGTGAMDFGVGGFIFGAAMVCPEVRRKSIEESRFNYLRKSLYSVWPLVFLGMGRLVIIKSIGYQEHSTEYGIHWNFFFTIIVVRLVTSLLLIIFPLNKSWIVAVSITVVYQLALDYTPLKRILLYGTDGSGTRVGFLNANREGIISTLGYVTIHMAGVQTGLYVLKGRAQVRDWIKATCWVFSVAVGFFISLHIVQVNIEAVSRRMANLAFCLWVVASSLMLLSCLLLSGIILSFAQFLIKGSLVPCSWKLIQSPTTHKNHSESLILEAEKNQPSLCLITALNRNQLFFFLLSNITTGLINLTMDTLHTGALWTLVVLSIYMFTNCLVIYVLDLQGKTIKFW
uniprot
proteins
ec_number
2.3.-.-
uniprot
proteins
function
FUNCTION: Acyltransferase that catalyzes the acyl transfer from an acyl-CoA at the 2-OH position of the inositol ring of a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol (glucosaminyl phosphatidylinositol, GlcN-PI) to generate a 2-acyl-6-alpha-D-glucosaminyl-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol (glucosaminyl acyl phosphatidylinositol, GlcN-(acyl)PI) and participates in the fourth step of GPI-anchor biosynthesis (By similarity). Required for the transport of GPI-anchored proteins to the plasma membrane (By similarity). Acylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity). {ECO:0000250|UniProtKB:Q7TSN4, ECO:0000250|UniProtKB:Q7Z7B1}.
uniprot
proteins
mass_dalton
56841
uniprot
proteins
pathway_participation
PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis. {ECO:0000250|UniProtKB:Q7TSN4}.
uniprot
proteins
protein_family
PIGW family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
503
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q7TSN4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q7TSN4}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 49..71; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 75..97; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 132..152; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 161..181; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 237..257; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 260..280; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 305..325; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 340..360; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 381..401; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 448..468; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 473..493; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins