NUCKS1
entrez
64710
canonical
uniprot
Q9H1E3
canonical
ensembl
ENSG00000069275
resolver
ensp
ENSP00000356110
resolver
ensp
ENSP00000545276
resolver
genesymbol
NUCKS1
resolver
genesymbol_syn
NUCKS
resolver
hgnc
HGNC:29923
resolver
uniprot
Q54AC0
resolver
uniprot
Q5PXE7
resolver
uniprot
Q9H1D6
resolver
uniprot
Q9H723
resolver
uniprot_entry
NUCKS_HUMAN
resolver
uniprot_sec
Q54AC0
resolver
uniprot_sec
Q5PXE7
resolver
uniprot_sec
Q9H1D6
resolver
uniprot_sec
Q9H723
resolver
amino_acid_sequence
MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPTKKIRSSPREAKNKRRSGKNSQEDSEDSEDKDVKTKKDDSHSAEDSEDEKEDHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPPEKKTSTSPPPEKSGDEGSEDEAPSGED
uniprot
proteins
function
FUNCTION: Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR) (PubMed:26323318). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1 (PubMed:26323318). {ECO:0000269|PubMed:26323318}.
uniprot
proteins
mass_dalton
27296
uniprot
proteins
post_translational_modification
PTM: Phosphorylated in an ATM-dependent manner in response to DNA damage (PubMed:26323318). Phosphorylated by CDK1 and casein kinase (PubMed:11298763). {ECO:0000269|PubMed:11298763, ECO:0000269|PubMed:26323318}.
uniprot
proteins
pubmed
11298763
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15381070
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16964243
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17487921
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
17693683
uniprot
proteins
pubmed
17924679
uniprot
proteins
pubmed
18220336
uniprot
proteins
pubmed
18318008
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19367720
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
26323318
uniprot
proteins
sequence_length
243
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11298763, ECO:0000269|PubMed:26323318}. Chromosome {ECO:0000269|PubMed:26323318}.
uniprot
proteins