PAIP2
entrez
51247
canonical
uniprot
Q9BPZ3
canonical
ensembl
ENSG00000120727
resolver
ensp
ENSP00000265192
resolver
ensp
ENSP00000378275
resolver
ensp
ENSP00000422508
resolver
ensp
ENSP00000551981
resolver
ensp
ENSP00000551982
resolver
ensp
ENSP00000587568
resolver
ensp
ENSP00000587571
resolver
ensp
ENSP00000587572
resolver
ensp
ENSP00000587573
resolver
ensp
ENSP00000587574
resolver
ensp
ENSP00000587575
resolver
ensp
ENSP00000624534
resolver
ensp
ENSP00000624535
resolver
ensp
ENSP00000624536
resolver
ensp
ENSP00000624537
resolver
ensp
ENSP00000764660
resolver
enst
ENST00000265192
resolver
enst
ENST00000394795
resolver
enst
ENST00000510080
resolver
enst
ENST00000881922
resolver
enst
ENST00000881923
resolver
enst
ENST00000917509
resolver
enst
ENST00000917512
resolver
enst
ENST00000917513
resolver
enst
ENST00000917514
resolver
enst
ENST00000917515
resolver
enst
ENST00000917516
resolver
enst
ENST00000954475
resolver
enst
ENST00000954476
resolver
enst
ENST00000954477
resolver
enst
ENST00000954478
resolver
genesymbol
PAIP2
resolver
genesymbol_syn
PAIP2A
resolver
hgnc
HGNC:17970
resolver
uniprot
B2RBI1
resolver
uniprot
D3DQC6
resolver
uniprot
Q49A06
resolver
uniprot
Q49AE6
resolver
uniprot
Q9H0Y5
resolver
uniprot
Q9P0Q8
resolver
uniprot_entry
PAIP2_HUMAN
resolver
uniprot_entry
Q49AE6_HUMAN
resolver
uniprot_sec
B2RBI1
resolver
uniprot_sec
D3DQC6
resolver
uniprot_sec
Q49A06
resolver
uniprot_sec
Q9H0Y5
resolver
uniprot_sec
Q9P0Q8
resolver
amino_acid_sequence
MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI
uniprot
proteins
function
FUNCTION: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. {ECO:0000269|PubMed:11172725}.
uniprot
proteins
mass_dalton
14984
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation by the proteasome. {ECO:0000269|PubMed:16804161}.
uniprot
proteins
protein_family
PAIP2 family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
11172725
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11287632
uniprot
proteins
pubmed
11438674
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16804161
uniprot
proteins
sequence_length
127
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11172725}.
uniprot
proteins