CCL23
entrez
6368
canonical
uniprot
P55773
canonical
ensembl
ENSG00000274736
resolver
ensembl
ENSG00000276114
resolver
ensp
ENSP00000481357
resolver
ensp
ENSP00000483546
resolver
ensp
ENSP00000484748
resolver
ensp
ENSP00000488270
resolver
enst
ENST00000610342
resolver
enst
ENST00000632633
resolver
genesymbol
CCL23
resolver
genesymbol_syn
MIP3
resolver
genesymbol_syn
MPIF1
resolver
genesymbol_syn
SCYA23
resolver
hgnc
HGNC:10622
resolver
uniprot
B7ZKQ3
resolver
uniprot
O00174
resolver
uniprot
O75950
resolver
uniprot
Q52LD4
resolver
uniprot_entry
CCL23_HUMAN
resolver
uniprot_sec
B7ZKQ3
resolver
uniprot_sec
O00174
resolver
uniprot_sec
O75950
resolver
uniprot_sec
Q52LD4
resolver
amino_acid_sequence
MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN
uniprot
proteins
function
FUNCTION: Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23. {ECO:0000269|PubMed:15905581}.
uniprot
proteins
mass_dalton
13443
uniprot
proteins
post_translational_modification
PTM: The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro. {ECO:0000269|PubMed:15905581}.
uniprot
proteins
protein_family
Intercrine beta (chemokine CC) family
uniprot
proteins
pubmed
10213461
uniprot
proteins
pubmed
11060285
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15905581
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
9104803
uniprot
proteins
pubmed
9129202
uniprot
proteins
pubmed
9558365
uniprot
proteins
sequence_length
120
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins