Jdp2
entrez
81703
canonical
uniprot
P97875
canonical
ensembl
ENSMUSG00000034271
resolver
ensp
ENSMUSP00000059724
resolver
ensp
ENSMUSP00000129985
resolver
ensp
ENSMUSP00000136823
resolver
ensp
ENSMUSP00000316030
resolver
enst
ENSMUST00000050687
resolver
enst
ENSMUST00000171754
resolver
enst
ENSMUST00000177587
resolver
genesymbol
Jdp2
resolver
genesymbol_syn
Jundm2
resolver
uniprot_entry
JDP2_MOUSE
resolver
amino_acid_sequence
MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK
uniprot
proteins
function
FUNCTION: Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin (By similarity). {ECO:0000250, ECO:0000269|PubMed:12707301, ECO:0000269|PubMed:14627710}.
uniprot
proteins
mass_dalton
18675
uniprot
proteins
mutagenesis
MUTAGEN 148; /note="T->A: Blocks phosphorylation by MAPK8."; /evidence="ECO:0000269|PubMed:11602244, ECO:0000269|PubMed:18307971
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments. {ECO:0000269|PubMed:11602244, ECO:0000269|PubMed:18307971}.; PTM: Polyubiquitinated; probably by IRF2BP1. {ECO:0000250}.
uniprot
proteins
protein_family
ATF subfamily
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
pubmed
11231009
uniprot
proteins
pubmed
11602244
uniprot
proteins
pubmed
12707301
uniprot
proteins
pubmed
14627710
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18307971
uniprot
proteins
sequence_length
163
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins