TMED7
entrez
51014
canonical
uniprot
Q9Y3B3
canonical
ensembl
ENSG00000134970
resolver
ensembl
ENSG00000251201
resolver
ensp
ENSP00000405926
resolver
genesymbol
TMED7
resolver
hgnc
HGNC:24253
resolver
uniprot
Q8NBU8
resolver
uniprot
Q8WUU6
resolver
uniprot
Q96K51
resolver
uniprot_entry
TMED7_HUMAN
resolver
uniprot_sec
Q8NBU8
resolver
uniprot_sec
Q8WUU6
resolver
uniprot_sec
Q96K51
resolver
amino_acid_sequence
MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
uniprot
proteins
function
FUNCTION: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications.
uniprot
proteins
mass_dalton
25172
uniprot
proteins
post_translational_modification
PTM: N-linked glycosylated in complex form containing terminal sialic acid. {ECO:0000269|PubMed:10359607}.
uniprot
proteins
protein_family
EMP24/GP25L family
uniprot
proteins
pubmed
10359607
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
12237308
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15372022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
16940185
uniprot
proteins
sequence_length
224
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Cycles between compartments of the early secretatory pathway.
uniprot
proteins
transmembrane_region
TRANSMEM 188..208; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins