Entpd3
entrez
215446
canonical
uniprot
Q8BFW6
canonical
ensembl
ENSMUSG00000041608
resolver
ensp
ENSMUSP00000036830
resolver
enst
ENSMUST00000047687
resolver
genesymbol
Entpd3
resolver
uniprot
E9PYV0
resolver
uniprot
Q3TC04
resolver
uniprot
Q3TDX3
resolver
uniprot_entry
ENTP3_MOUSE
resolver
uniprot_sec
E9PYV0
resolver
uniprot_sec
Q3TC04
resolver
uniprot_sec
Q3TDX3
resolver
amino_acid_sequence
MFTVMTRQPCEQAGFRALSRTPAIVTLVVLLVSIVVLVTLTLIQIRHPQVLPPGLKYGVVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCILKVKEQVPEHLHGSTRIYLGATAGMRLLRLQNETAAREVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVAGEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGQNEAEKKFLAMLLQSPSTEANISNPCYPQGYSTAFTLGHVFGSLCTEKQRPESYNSSKSVTFMGTGDPRLCREKVASVFDFNACQEQDACSFDGIYQPKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPALLSRFDETYARSYCFSAHYIYHLLVNGYKFTEETWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIHLPIQPPVFMGVLAFFTAIALLCLAFLLYLCSSFRTKERSENAFDQAVDSD
uniprot
proteins
ec_number
3.6.1.5
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (PubMed:15130768). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (PubMed:15130768). This activity contributes to the regulation of extracellular levels of nucleotides (PubMed:15130768). Has a threefold preference for the hydrolysis of ATP and UTP over ADP (PubMed:15130768). Does not hydrolyzes AMP (PubMed:15130768). {ECO:0000269|PubMed:15130768}.
uniprot
proteins
mass_dalton
58984
uniprot
proteins
protein_family
GDA1/CD39 NTPase family
uniprot
proteins
pubmed
15130768
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
529
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15130768}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 23..43; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 486..506; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins