Hmox2
entrez
15369
canonical
uniprot
O70252
canonical
ensembl
ENSMUSG00000004070
resolver
ensp
ENSMUSP00000004172
resolver
ensp
ENSMUSP00000112397
resolver
ensp
ENSMUSP00000113110
resolver
enst
ENSMUST00000004172
resolver
enst
ENSMUST00000118885
resolver
enst
ENSMUST00000120232
resolver
genesymbol
Hmox2
resolver
uniprot
O70626
resolver
uniprot
Q544R7
resolver
uniprot_entry
HMOX2_MOUSE
resolver
uniprot_entry
Q544R7_MOUSE
resolver
uniprot_sec
O70626
resolver
amino_acid_sequence
MSSEVETSEGVDESEKNSMAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKAALIKDMKYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLNLKTKERIVEEANKAFEYNMQIFSELDQAGSMLARETLEDGLPVHDGKGDIRKCPFYAAQPDKGTLGGSNCPFQTTVAVLRKPSLQLILAASVALVAGLLAWYYM
uniprot
proteins
ec_number
1.14.14.18
uniprot
proteins
function
FUNCTION: [Heme oxygenase 2]: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. {ECO:0000250|UniProtKB:P30519}.; FUNCTION: [Heme oxygenase 2 soluble form]: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. {ECO:0000250|UniProtKB:P30519}.
uniprot
proteins
mass_dalton
35739
uniprot
proteins
post_translational_modification
PTM: A soluble form arises by proteolytic removal of the membrane anchor. {ECO:0000250|UniProtKB:P30519}.; PTM: S-nitrosylated by BLVRB. {ECO:0000250|UniProtKB:P30519}.
uniprot
proteins
protein_family
Heme oxygenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9795203
uniprot
proteins
sequence_length
315
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Microsome membrane {ECO:0000250|UniProtKB:P30519}; Single-pass type IV membrane protein {ECO:0000255}; Cytoplasmic side {ECO:0000250|UniProtKB:P09601}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P09601}; Single-pass type IV membrane protein {ECO:0000255}; Cytoplasmic side {ECO:0000250|UniProtKB:P09601}.
uniprot
proteins
transmembrane_region
TRANSMEM 295..315; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins