ATP5MF
entrez
9551
canonical
uniprot
P56134
canonical
ensembl
ENSG00000241468
resolver
ensp
ENSP00000292475
resolver
ensp
ENSP00000352890
resolver
ensp
ENSP00000377740
resolver
ensp
ENSP00000418197
resolver
genesymbol
ATP5MF
resolver
genesymbol_syn
ATP5J2
resolver
genesymbol_syn
ATP5JL
resolver
hgnc
HGNC:848
resolver
uniprot
C9J8H9
resolver
uniprot
F8W7V3
resolver
uniprot
O76079
resolver
uniprot
Q6IBB3
resolver
uniprot
Q96L83
resolver
uniprot
Q9BTI8
resolver
uniprot_entry
ATPK_HUMAN
resolver
uniprot_sec
C9J8H9
resolver
uniprot_sec
F8W7V3
resolver
uniprot_sec
O76079
resolver
uniprot_sec
Q6IBB3
resolver
uniprot_sec
Q96L83
resolver
uniprot_sec
Q9BTI8
resolver
amino_acid_sequence
MASVGECPAPVPVKDKKLLEVKLGELPSWILMRDFSPSGIFGAFQRGYYRYYNKYINVKKGSISGITMVLACYVLFSYSFSYKHLKHERLRKYH
uniprot
proteins
function
FUNCTION: Subunit f, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (PubMed:37244256). {ECO:0000250|UniProtKB:P19483, ECO:0000269|PubMed:37244256, ECO:0000305|PubMed:37244256}.
uniprot
proteins
mass_dalton
10918
uniprot
proteins
protein_family
ATPase F chain family
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
37244256
uniprot
proteins
pubmed
9653160
uniprot
proteins
sequence_length
94
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion. Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 68..85; /note="Helical"; /evidence="ECO:0000269|PubMed:37244256, ECO:0007744|PDB:8H9V
uniprot
proteins