Cdca7l
entrez
619566
canonical
uniprot
Q4G059
canonical
ensembl
ENSRNOG00000005410
resolver
ensembl
ENSRNOG00055004938
resolver
ensembl
ENSRNOG00060014878
resolver
ensp
ENSRNOP00000079873
resolver
ensp
ENSRNOP00055005970
resolver
ensp
ENSRNOP00060020301
resolver
enst
ENSRNOT00000103690
resolver
enst
ENSRNOT00055007920
resolver
enst
ENSRNOT00060025467
resolver
genesymbol
Cdca7l
resolver
uniprot_entry
CDA7L_RAT
resolver
amino_acid_sequence
MELATRSQIPKEVADIFNAPSDDEEFVGFQDDVPMENLSESCGSLDSLELEKQNACLHSKYFTEELRRIFKEDTDSDNEDFEGFTESELNIGSNPELIESELSDGDKTHPMMSDEEDDDDEEEAAPRRGRQSTRSSFGLRVAFQFPTKKTAKTPDKNSPHLLGGKTDLRREKSCRQPKEKEDSASDAEDESRAESQETSDALLKRAMNIKENKAMLAQLLAELNSVPDFFPVRTPPSASRRRTPRRAFSEGQITRRVNPTRSARPPEKFALENFTFSATKLTEELYSFRRRKTISGGKCQKYRRHRISSFRSVKDITEEELENIAITVRDKVYDKVLGNTCHQCRQKTIDTKTVCRNQGCGGVRGQFCGPCLRNRYGEDVRTALLDPKWTCPPCRGICNCSYCRRRDGRCATGILIHLAKFYGYDNVKEYLESLQKQL
uniprot
proteins
function
FUNCTION: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
49973
uniprot
proteins
post_translational_modification
PTM: Phosphorylation increases its interaction with PSIP1. {ECO:0000250|UniProtKB:Q96GN5}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
438
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction (By similarity). {ECO:0000250}.
uniprot
proteins