Riox2
entrez
266670
canonical
uniprot
Q8CFC1
canonical
ensembl
ENSRNOG00000001680
resolver
ensembl
ENSRNOG00055013749
resolver
ensembl
ENSRNOG00060017618
resolver
ensembl
ENSRNOG00065014249
resolver
ensp
ENSRNOP00000081634
resolver
ensp
ENSRNOP00055019249
resolver
ensp
ENSRNOP00060024352
resolver
ensp
ENSRNOP00065018290
resolver
enst
ENSRNOT00000100511
resolver
enst
ENSRNOT00055023645
resolver
enst
ENSRNOT00060030168
resolver
enst
ENSRNOT00065023516
resolver
genesymbol
Riox2
resolver
genesymbol_syn
Mina
resolver
genesymbol_syn
Mina53
resolver
uniprot_entry
RIOX2_RAT
resolver
amino_acid_sequence
MPKKVKPTGDENEEESVPCKQVKEELPNTLSVLNFDSPSSFFESLISPIKVETFFKEFWEQKPLLIQRDDPSLAAYYQSLFSLSDLRSLCSQGLYYGRDVNVCRCIGGKKKVLNKDGKAQFLQLRKDFDQKRATIQFHQPQRFKDELWRIQEKLECYFGSLVGSNVYMTPAGSQGLPPHYDDVEVFILQLEGRKRWRLYSPTVPLAREYSVEPEDRIGTPTHDFLLKPGDLLYFPRGTIHQAETPSGLAHSIHLTISTYQNNSWGDYLLDSISGLVFDIAKEDVALRTGMPRRMLMNVETPADVTRKLSGFLRTLADQLEGRKELLSSDMKKDFVMHRLPPFCVGNGTESMNPGGKLPRLNSIVRLQFKDHIVLTVGPDQNQSDEAQQKVVYIYHSLKNERQTHMMGKEVETEIYGLRFPLSYVDALKQIWCGSPVRVKDLKLGTDEEKENLAVSLWTECLVHVL
uniprot
proteins
ec_number
1.14.11.79
uniprot
proteins
function
FUNCTION: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39' (By similarity). May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. {ECO:0000250, ECO:0000269|PubMed:12091391}.
uniprot
proteins
mass_dalton
53216
uniprot
proteins
protein_family
MINA53 subfamily
uniprot
proteins
protein_family
ROX family
uniprot
proteins
pubmed
12091391
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
465
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8IUF8}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q8IUF8}.
uniprot
proteins