Cpne1
entrez
266692
canonical
uniprot
Q8C166
canonical
ensembl
ENSMUSG00000074643
resolver
ensp
ENSMUSP00000105236
resolver
ensp
ENSMUSP00000105237
resolver
enst
ENSMUST00000109607
resolver
enst
ENSMUST00000109608
resolver
genesymbol
Cpne1
resolver
uniprot
Q3U893
resolver
uniprot
Q925K4
resolver
uniprot
Q925K5
resolver
uniprot_entry
CPNE1_MOUSE
resolver
uniprot_entry
Q3U893_MOUSE
resolver
uniprot_sec
Q925K4
resolver
uniprot_sec
Q925K5
resolver
amino_acid_sequence
MAHCVTLVQLSVSCEHLIDKDIGSKSDPLCVLLQDVGGAWAELCRTERVRNCSSPEFSKTLQIEYHFETVQKLRFGIYDIDNKTPELGDDDFLGGAECSLGQIVSSQTLTLPLMLKPGKPAGRGTITVSAQELKDSRVVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWQLAYRTEVVKNNLNPTWKRFSVSLQHFCGGDLSTPIQVRCSDYDSDGSHDLIGTFHTTLAQLQAVPAEFECVHPEKQQRKKNYRNSGTVRVKTCRVETEYSFLDYVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLTALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVARFAAQAAQQRSASQYFVLLLLTDGAVTDVEATCKAVVDASKLPMSVIIVGVGGADFEVMEQLDADGGPLRTRSGEAAARDIVQFVPYRRFQNAPRETLAQTVLAEVPTQMVSYFRAQGWAPLKAPPTPGKGPAQAPQA
uniprot
proteins
function
FUNCTION: Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF receptor signaling pathway in a calcium-dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit. Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL. {ECO:0000250|UniProtKB:Q99829}.
uniprot
proteins
mass_dalton
58887
uniprot
proteins
protein_family
Copine family
uniprot
proteins
pubmed
11471062
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
536
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q99829}. Cytoplasm {ECO:0000250|UniProtKB:Q99829}. Cell membrane {ECO:0000250|UniProtKB:Q99829}. Note=Translocates to the cell membrane in a calcium-dependent manner. {ECO:0000250|UniProtKB:Q99829}.
uniprot
proteins