Aanat
entrez
11298
canonical
uniprot
O88816
canonical
ensembl
ENSMUSG00000020804
resolver
ensp
ENSMUSP00000122895
resolver
enst
ENSMUST00000153476
resolver
genesymbol
Aanat
resolver
genesymbol_syn
Snat
resolver
uniprot
Q14A64
resolver
uniprot_entry
Q14A64_MOUSE
resolver
uniprot_entry
SNAT_MOUSE
resolver
amino_acid_sequence
MLNINSLKPEALHLPLGTSEFLGCQRRHTLPASEFRCLTPEDATSAFEIEREAFISVSGTCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLTQESLTLHRPGGRTAHLHVLAVHRTFRQQGKGSVLLWRYLHHLGSQPAVRRAVLMCEDALVPFYEKFGFQAVGPCAITVGSLTFTELQCSLRCHAFLRRNSGC
uniprot
proteins
ec_number
2.3.1.87
uniprot
proteins
function
FUNCTION: Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin. {ECO:0000250|UniProtKB:Q29495}.
uniprot
proteins
mass_dalton
23069
uniprot
proteins
pathway_participation
PATHWAY: Aromatic compound metabolism; melatonin biosynthesis; melatonin from serotonin: step 1/2.
uniprot
proteins
post_translational_modification
PTM: cAMP-dependent phosphorylation on both N-terminal Thr-29 and C-terminal Ser-203 regulates AANAT activity by promoting interaction with 14-3-3 proteins. {ECO:0000250}.
uniprot
proteins
protein_family
AANAT subfamily
uniprot
proteins
protein_family
Acetyltransferase family
uniprot
proteins
pubmed
20308563
uniprot
proteins
pubmed
9708862
uniprot
proteins
pubmed
9838107
uniprot
proteins
sequence_length
205
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q16613}.
uniprot
proteins