ENDOD1
entrez
23052
canonical
uniprot
O94919
canonical
ensembl
ENSG00000149218
resolver
ensp
ENSP00000278505
resolver
enst
ENST00000278505
resolver
genesymbol
ENDOD1
resolver
genesymbol_syn
KIAA0830
resolver
hgnc
HGNC:29129
resolver
uniprot
A8K6K8
resolver
uniprot
Q6GQY5
resolver
uniprot
Q8TAQ8
resolver
uniprot_entry
ENDD1_HUMAN
resolver
uniprot_sec
A8K6K8
resolver
uniprot_sec
Q6GQY5
resolver
uniprot_sec
Q8TAQ8
resolver
amino_acid_sequence
MGTARWLALGSLFALAGLLEGRLVGEEEAGFGECDKFFYAGTPPAGLAADSHVKICQRAEGAERFATLYSTRDRIPVYSAFRAPRPAPGGAEQRWLVEPQIDDPNSNLEEAINEAEAITSVNSLGSKQALNTDYLDSDYQRGQLYPFSLSSDVQVATFTLTNSAPMTQSFQERWYVNLHSLMDRALTPQCGSGEDLYILTGTVPSDYRVKDKVAVPEFVWLAACCAVPGGGWAMGFVKHTRDSDIIEDVMVKDLQKLLPFNPQLFQNNCGETEQDTEKMKKILEVVNQIQDEERMVQSQKSSSPLSSTRSKRSTLLPPEASEGSSSFLGKLMGFIATPFIKLFQLIYYLVVAILKNIVYFLWCVTKQVINGIESCLYRLGSATISYFMAIGEELVSIPWKVLKVVAKVIRALLRILCCLLKAICRVLSIPVRVLVDVATFPVYTMGAIPIVCKDIALGLGGTVSLLFDTAFGTLGGLFQVVFSVCKRIGYKVTFDNSGEL
uniprot
proteins
ec_number
3.1.30.-
uniprot
proteins
function
FUNCTION: May act as a DNase and a RNase. Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. {ECO:0000269|PubMed:32614325}.
uniprot
proteins
mass_dalton
55017
uniprot
proteins
protein_family
DNA/RNA non-specific endonuclease family
uniprot
proteins
pubmed
10048485
uniprot
proteins
pubmed
11921445
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
32614325
uniprot
proteins
sequence_length
500
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
uniprot
proteins