GNLY
entrez
10578
canonical
uniprot
P22749
canonical
ensembl
ENSG00000115523
resolver
ensp
ENSP00000263863
resolver
ensp
ENSP00000387116
resolver
ensp
ENSP00000436423
resolver
ensp
ENSP00000770080
resolver
enst
ENST00000524600
resolver
genesymbol
GNLY
resolver
genesymbol_syn
LAG2
resolver
genesymbol_syn
NKG5
resolver
genesymbol_syn
TLA519
resolver
hgnc
HGNC:4414
resolver
uniprot
B4E3H9
resolver
uniprot
F6U7F4
resolver
uniprot
P09325
resolver
uniprot
Q6GU08
resolver
uniprot_entry
B4E3H9_HUMAN
resolver
uniprot_entry
F6U7F4_HUMAN
resolver
uniprot_entry
GNLY_HUMAN
resolver
uniprot_sec
P09325
resolver
uniprot_sec
Q6GU08
resolver
amino_acid_sequence
MATWALLLLAAMLLGNPGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRLCIPSTGPL
uniprot
proteins
function
FUNCTION: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.
uniprot
proteins
mass_dalton
16374
uniprot
proteins
post_translational_modification
PTM: A 9 kDa form is produced by proteolytic processing of a 15 kDa protein. {ECO:0000269|PubMed:10449094}.
uniprot
proteins
pubmed
10449094
uniprot
proteins
pubmed
10644038
uniprot
proteins
pubmed
12488100
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
2212946
uniprot
proteins
pubmed
2434598
uniprot
proteins
pubmed
8423048
uniprot
proteins
pubmed
9756476
uniprot
proteins
sequence_length
145
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted. Note=Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.
uniprot
proteins