L3mbtl2
entrez
214669
canonical
uniprot
P59178
canonical
ensembl
ENSMUSG00000022394
resolver
ensp
ENSMUSP00000023029
resolver
ensp
ENSMUSP00000133967
resolver
ensp
ENSMUSP00000134333
resolver
enst
ENSMUST00000023029
resolver
enst
ENSMUST00000172748
resolver
enst
ENSMUST00000174229
resolver
genesymbol
L3mbtl2
resolver
genesymbol_syn
M4mbt
resolver
uniprot
G3UY70
resolver
uniprot
G3UZ40
resolver
uniprot
Q80XB1
resolver
uniprot
Q8BHD5
resolver
uniprot_entry
G3UY70_MOUSE
resolver
uniprot_entry
G3UZ40_MOUSE
resolver
uniprot_entry
LMBL2_MOUSE
resolver
uniprot_entry
Q80XB1_MOUSE
resolver
uniprot_sec
Q8BHD5
resolver
amino_acid_sequence
MEKPRGTEEAPSSEPMEEEEEDDLDLFGGYDSFRSYNSSAGSESSSYLEESSEAENEDREAGELPTSPLHLFSSANNRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHAQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMKYPFRQGMRLEVVDKTQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSDRRCDMSHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGSICVATICKVLLDGYLMICVDGGPSTDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFAWETYLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNEYDQWVDCESPDIYPVGWCELTGYQLQPPVSAEPNTPQKGKDTTKKKKKQFGKKRKRIPSAKTRPLRQGSKKPLLEDNLEALGVSEPVPDDIIAVCVKEEHQDISSLDRSPSPQLPLPIESIKQERNN
uniprot
proteins
function
FUNCTION: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
78971
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000269|PubMed:14597177}.
uniprot
proteins
pubmed
14597177
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
703
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14597177}.
uniprot
proteins