CAPG
entrez
822
canonical
uniprot
P40121
canonical
ensembl
ENSG00000042493
resolver
ensp
ENSP00000263867
resolver
ensp
ENSP00000386965
resolver
ensp
ENSP00000387063
resolver
ensp
ENSP00000550886
resolver
ensp
ENSP00000550894
resolver
ensp
ENSP00000550896
resolver
ensp
ENSP00000550897
resolver
ensp
ENSP00000550902
resolver
ensp
ENSP00000588334
resolver
ensp
ENSP00000669380
resolver
genesymbol
CAPG
resolver
genesymbol
HEL-S-66
resolver
genesymbol_syn
AFCP
resolver
genesymbol_syn
MCP
resolver
hgnc
HGNC:1474
resolver
uniprot
B2R9S4
resolver
uniprot
B8ZZS7
resolver
uniprot
D6W5K8
resolver
uniprot
Q53SA7
resolver
uniprot
V9HW69
resolver
uniprot_entry
B2R9S4_HUMAN
resolver
uniprot_entry
CAPG_HUMAN
resolver
uniprot_entry
V9HW69_HUMAN
resolver
uniprot_sec
B8ZZS7
resolver
uniprot_sec
D6W5K8
resolver
uniprot_sec
Q53SA7
resolver
amino_acid_sequence
MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK
uniprot
proteins
function
FUNCTION: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
uniprot
proteins
mass_dalton
38499
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
Villin/gelsolin family
uniprot
proteins
pubmed
1322908
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17081065
uniprot
proteins
pubmed
18266911
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
7814409
uniprot
proteins
pubmed
7851883
uniprot
proteins
sequence_length
348
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17081065, ECO:0000269|PubMed:18266911}. Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P24452}. Cell projection, ruffle {ECO:0000250|UniProtKB:P24452}. Note=In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia. {ECO:0000250|UniProtKB:P24452}.
uniprot
proteins