Plpp7
entrez
227721
canonical
uniprot
Q91WB2
canonical
ensembl
ENSMUSG00000051373
resolver
ensp
ENSMUSP00000054337
resolver
ensp
ENSMUSP00000141597
resolver
ensp
ENSMUSP00000312978
resolver
enst
ENSMUST00000057423
resolver
enst
ENSMUST00000140762
resolver
genesymbol
Plpp7
resolver
genesymbol_syn
Net39
resolver
genesymbol_syn
Ppapdc3
resolver
uniprot
A0A0A6YWL5
resolver
uniprot_entry
A0A0A6YWL5_MOUSE
resolver
uniprot_entry
PLPP7_MOUSE
resolver
amino_acid_sequence
MPASQSRARARDRNNVLNRAEFLSLNQPPKGTQEPRSSGRKASGPSTQPPPSSDGARERRQSQQLPEEDCMQLNPSFKGIAFNSLLAIDICMSKRLGVCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVRSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPGLLDYLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYFQFRLVELVWMSSNTCQMLISAW
uniprot
proteins
function
FUNCTION: Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity. Knockdown in myoblasts strongly promotes differentiation, whereas overexpression represses myogenesis. {ECO:0000269|PubMed:19704009}.
uniprot
proteins
mass_dalton
29710
uniprot
proteins
protein_family
PA-phosphatase related phosphoesterase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17062158
uniprot
proteins
pubmed
19704009
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
271
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus envelope. Endoplasmic reticulum membrane. Membrane; Multi-pass membrane protein. Note=Both the N- and C-terminal are exposed to the cytoplasm/nucleoplasm.
uniprot
proteins
transmembrane_region
TRANSMEM 113..133; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 142..162; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 203..223; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 240..260; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins