ING1
entrez
3621
canonical
uniprot
Q9UK53
canonical
ensembl
ENSG00000153487
resolver
ensp
ENSP00000328436
resolver
ensp
ENSP00000345202
resolver
ensp
ENSP00000364929
resolver
ensp
ENSP00000364930
resolver
enst
ENST00000375774
resolver
genesymbol
ING1
resolver
hgnc
HGNC:6062
resolver
uniprot
A0A0C4DFW2
resolver
uniprot
O00532
resolver
uniprot
O43658
resolver
uniprot
Q53ZR3
resolver
uniprot
Q5T9G8
resolver
uniprot
Q5T9G9
resolver
uniprot
Q5T9H0
resolver
uniprot
Q5T9H1
resolver
uniprot
Q9H007
resolver
uniprot
Q9HD98
resolver
uniprot
Q9HD99
resolver
uniprot
Q9NS83
resolver
uniprot
Q9P0U6
resolver
uniprot
Q9UBC6
resolver
uniprot
Q9UIJ1
resolver
uniprot
Q9UIJ2
resolver
uniprot
Q9UIJ3
resolver
uniprot
Q9UIJ4
resolver
uniprot
Q9UK52
resolver
uniprot_entry
A0A0C4DFW2_HUMAN
resolver
uniprot_entry
ING1_HUMAN
resolver
uniprot_sec
O00532
resolver
uniprot_sec
O43658
resolver
uniprot_sec
Q53ZR3
resolver
uniprot_sec
Q5T9G8
resolver
uniprot_sec
Q5T9G9
resolver
uniprot_sec
Q5T9H0
resolver
uniprot_sec
Q5T9H1
resolver
uniprot_sec
Q9H007
resolver
uniprot_sec
Q9HD98
resolver
uniprot_sec
Q9HD99
resolver
uniprot_sec
Q9NS83
resolver
uniprot_sec
Q9P0U6
resolver
uniprot_sec
Q9UBC6
resolver
uniprot_sec
Q9UIJ1
resolver
uniprot_sec
Q9UIJ2
resolver
uniprot_sec
Q9UIJ3
resolver
uniprot_sec
Q9UIJ4
resolver
uniprot_sec
Q9UK52
resolver
amino_acid_sequence
MSFVECPYHSPAERLVAEADEGGPSAITGMGLCFRCLLFSFSGRSGVEGGRVDLNVFGSLGLQPWIGSSRCWGGPCSSALRCGWFSSWPPPSKSAIPIGGGSRGAGRVSRWPPPHWLEAWRVSPLPLSPLSPATFGRGFIAVAVIPGLWARGRGCSSDRLPRPAGPARRQFQAASLLTRGWGRAWPWKQILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
uniprot
proteins
disease_involvement
DISEASE: Squamous cell carcinoma of the head and neck (HNSCC) [MIM:275355]: A non-melanoma skin cancer affecting the head and neck. The hallmark of cutaneous SCC is malignant transformation of normal epidermal keratinocytes. {ECO:0000269|PubMed:10866301}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene. {ECO:0000269|PubMed:9440695}.
uniprot
proteins
mass_dalton
46738
uniprot
proteins
mutagenesis
MUTAGEN 378; /note="W->A: Unable to stimulate DNA repair after UV irradiation or promote DNA-damage-induced apoptosis."; /evidence="ECO:0000269|PubMed:18533182
uniprot
proteins
protein_family
ING family
uniprot
proteins
pubmed
10626813
uniprot
proteins
pubmed
10779953
uniprot
proteins
pubmed
10807544
uniprot
proteins
pubmed
10866301
uniprot
proteins
pubmed
11481424
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16728974
uniprot
proteins
pubmed
18533182
uniprot
proteins
pubmed
22419112
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
8944021
uniprot
proteins
pubmed
9440695
uniprot
proteins
sequence_length
422
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins