Ddo
entrez
685325
canonical
uniprot
D3ZDM7
canonical
ensembl
ENSRNOG00000000582
resolver
ensembl
ENSRNOG00055000655
resolver
ensembl
ENSRNOG00060007002
resolver
ensembl
ENSRNOG00065008742
resolver
ensp
ENSRNOP00000000710
resolver
ensp
ENSRNOP00055000880
resolver
ensp
ENSRNOP00060008612
resolver
ensp
ENSRNOP00065010360
resolver
enst
ENSRNOT00000000710
resolver
enst
ENSRNOT00055001122
resolver
enst
ENSRNOT00060011491
resolver
enst
ENSRNOT00065013913
resolver
genesymbol
Ddo
resolver
genesymbol_syn
LOC100911156
resolver
uniprot
A6KTC0
resolver
uniprot_entry
OXDD_RAT
resolver
uniprot_sec
A6KTC0
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by aminooxyacetic acid, malonate, meso-tartrate and potassium bromide. {ECO:0000269|PubMed:25747990, ECO:0000269|PubMed:32376478}.
uniprot
proteins
amino_acid_sequence
MDTVRIAVVGAGVIGLSTAACVSQLVPRCSVTVISDRFTPDTTSNVAAGMLIPPTYPDTPVPTLKRWFRETFQHLSEIARSAEAVDAGIHLVSGWQIFRSVPTEEVPFWADVVLGFREMTEAELKRFPQYEFGQAFTTLKCETSAYLPWLEKRIKGSGGLLLTRRIEDLWELQPSFDIVVNCSGLGSRRLVGDATVSPVRGQVLQAQAPWVKHFIRDGGGLTYVYPGTSYVTLGGSRQTGDWNLSPDAELSREIFSRCCALEPSLHRACDIKEKVGLRPSRPGVRLQKEILVRGEQRLPVVHNYGHGSGGISVHWGSALEATRLVMECVHTLRTPASLSKL
uniprot
proteins
ec_number
1.4.3.1
uniprot
proteins
function
FUNCTION: Selectively catalyzes the oxidative deamination of acidic amino acids (PubMed:1991137, PubMed:25747990, PubMed:29292239, PubMed:32376478). Suppresses the level of D-aspartate in the brain, an amino acid that can act as an agonist for glutamate receptors (By similarity). Protects the organism from the toxicity of D-amino acids (PubMed:7903300). May also function in the intestine (By similarity). {ECO:0000250|UniProtKB:Q922Z0, ECO:0000269|PubMed:1991137, ECO:0000269|PubMed:25747990, ECO:0000269|PubMed:29292239, ECO:0000269|PubMed:32376478, ECO:0000269|PubMed:7903300}.
uniprot
proteins
mass_dalton
37543
uniprot
proteins
protein_family
DAMOX/DASOX family
uniprot
proteins
pubmed
12209855
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15632090
uniprot
proteins
pubmed
1991137
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
25747990
uniprot
proteins
pubmed
29292239
uniprot
proteins
pubmed
32376478
uniprot
proteins
pubmed
7903300
uniprot
proteins
sequence_length
341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome matrix {ECO:0000269|PubMed:12209855, ECO:0000269|PubMed:1991137}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q99489}. Note=Active in the peroxisomal matrix. {ECO:0000250|UniProtKB:Q99489}.
uniprot
proteins