Ripor1
entrez
75687
canonical
uniprot
Q68FE6
canonical
ensembl
ENSMUSG00000038604
resolver
ensp
ENSMUSP00000039966
resolver
ensp
ENSMUSP00000269164
resolver
ensp
ENSMUSP00000332337
resolver
enst
ENSMUST00000043531
resolver
genesymbol
Ripor1
resolver
genesymbol_syn
Fam65a
resolver
genesymbol_syn
Kiaa1930
resolver
uniprot
G5E8A2
resolver
uniprot
Q80T73
resolver
uniprot
Q8K0T1
resolver
uniprot
Q9D6R4
resolver
uniprot_entry
RIPR1_MOUSE
resolver
uniprot_sec
G5E8A2
resolver
uniprot_sec
Q80T73
resolver
uniprot_sec
Q8K0T1
resolver
uniprot_sec
Q9D6R4
resolver
amino_acid_sequence
MMSLSVRPQRRLLSARVSRSQSFAGVLGSHERGPRSFTVFSPPGPPRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQRQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSTPKPLVQQPEPLPVQVAFRRPESLTSGSMDEEPAMTPSLVNGHAPYSRTLSHISEASVDAALTEAVEAVDSQSPIPGPSPLVYPDSTHVERVSSVLPVLNNGHSATSPALSTTGPAPTFIDPAPTTQLDLVHKTTDSAPSELPSITHTTTSSAYSAVSLVNSVPSLTSTTIGSAHTTTPSPLTSTGSVPNATDSTQATPSPTHSTPSPTHTTIRLTHTTVSPTHSSPSPIHTTPSPTHTTVSPTCTTPSSGHSTTSPTQEAKMSTHTTGAVGPVQTTTSPISTTESPSPSTDVAIISSSSAESTGPGTEPLPCSHPASPPYTKADPTASCTSYQSLASSGSKPLTSPAPDSPEQIPKSPSSSPSSSAPEPQHSEHNLAAVAQAPVPEATGGAGDRRLEEALGTLMSALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDNDGPGDRHTSSPEVVAEDRLDSSNGQSLSTGCSALDATLVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFQEVCERSKLWGNSATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICSVERVLLTFCSQYGARLSLRQPGLAEAVCVKFLEDALGQKLPRRPQPGPGEQFTIFQFWSYVEALDSPSMDAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRLRKDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDGDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRQLEESLDALPCIFGPSSMASTAF
uniprot
proteins
function
FUNCTION: Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation. {ECO:0000250|UniProtKB:Q6ZS17}.
uniprot
proteins
mass_dalton
132352
uniprot
proteins
protein_family
RIPOR family
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17251388
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1223
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17251388}. Golgi apparatus {ECO:0000250|UniProtKB:Q6ZS17}. Note=Localizes to the podocyte major processes and cell body (PubMed:17251388). Colocalized with STK26 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with STK26 upon serum stimulation in a Rho- and PDCD10-dependent manner (By similarity). {ECO:0000250|UniProtKB:Q6ZS17, ECO:0000269|PubMed:17251388}.
uniprot
proteins