Tbrg1
entrez
21376
canonical
uniprot
Q3UB74
canonical
ensembl
ENSMUSG00000011114
resolver
ensp
ENSMUSP00000112600
resolver
enst
ENSMUST00000117654
resolver
genesymbol
Tbrg1
resolver
genesymbol_syn
Niam
resolver
uniprot
Q3TLE7
resolver
uniprot
Q3UCG2
resolver
uniprot
Q3YBR3
resolver
uniprot
Q6P067
resolver
uniprot
Q80XA1
resolver
uniprot
Q8CGC5
resolver
uniprot_entry
TBRG1_MOUSE
resolver
uniprot_sec
Q3TLE7
resolver
uniprot_sec
Q3UCG2
resolver
uniprot_sec
Q3YBR3
resolver
uniprot_sec
Q6P067
resolver
uniprot_sec
Q80XA1
resolver
uniprot_sec
Q8CGC5
resolver
amino_acid_sequence
MSVLSGLASEPRTPLSSKARMKRLPRKSQNEKYRLKYLRLRRAAKATVFENASICDEIARLEEKFLKAKEERRYLLKKLLQIHALTEGEPQAAAPSHSSSLPLPYGVTSSVGTMQGAGPSTGAEEPFAKKSKKEKKEKGKENSKLEVLKKTSKKKKMEGGARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPQNTIVGSSADACYEELLRAISATTGKLMPNPLSCGADFFGFSHPTIHNLIQSCPEAQNCVNYQWVKFDACKPRKGQLSQELPENDATMSLEAFQTQTFDDDHDDSILPGSLDLPELQHEAFVSSYQPEFLTHEPLVDTDLQHLKSPSQCSPIQSSD
uniprot
proteins
function
FUNCTION: Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. {ECO:0000269|PubMed:17110379}.
uniprot
proteins
mass_dalton
44881
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated; mediated by MDM2 and leading to its subsequent proteasomal degradation. {ECO:0000250}.
uniprot
proteins
protein_family
TBRG1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17110379
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
7654366
uniprot
proteins
sequence_length
406
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17110379}.
uniprot
proteins