RABAC1
entrez
10567
canonical
uniprot
Q9UI14
canonical
ensembl
ENSG00000105404
resolver
ensp
ENSP00000222008
resolver
enst
ENST00000222008
resolver
genesymbol
RABAC1
resolver
genesymbol_syn
PRA1
resolver
genesymbol_syn
PRAF1
resolver
hgnc
HGNC:9794
resolver
uniprot
Q7Z4Y2
resolver
uniprot
Q9Y3R1
resolver
uniprot_entry
PRAF1_HUMAN
resolver
uniprot_sec
Q7Z4Y2
resolver
uniprot_sec
Q9Y3R1
resolver
amino_acid_sequence
MAAQKDQQKDAEAEGLSGTTLLPKLIPSGAGREWLERRRATIRPWSTFVDQQRFSRPRNLGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLESKLVLFGREVSPAHQYALAGGISFPFFWLAGAGSAVFWVLGATLVVIGSHAAFHQIEAVDGEELQMEPV
uniprot
proteins
function
FUNCTION: General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. {ECO:0000250|UniProtKB:O35394}.
uniprot
proteins
mass_dalton
20648
uniprot
proteins
protein_family
PRA1 family
uniprot
proteins
pubmed
10329441
uniprot
proteins
pubmed
11520070
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15922294
uniprot
proteins
pubmed
16481131
uniprot
proteins
pubmed
21269460
uniprot
proteins
sequence_length
185
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O35394}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:O35394}. Golgi apparatus {ECO:0000250|UniProtKB:O35394}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:O35394}. Note=According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles. {ECO:0000250|UniProtKB:O35394}.
uniprot
proteins
transmembrane_region
TRANSMEM 79..94; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 95..112; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 132..148; /note="Helical"; /evidence="ECO:0000250"; TRANSMEM 149..165; /note="Helical"; /evidence="ECO:0000250
uniprot
proteins