TUBGCP3
entrez
10426
canonical
uniprot
Q96CW5
canonical
ensembl
ENSG00000126216
resolver
ensp
ENSP00000261965
resolver
ensp
ENSP00000364821
resolver
ensp
ENSP00000478276
resolver
ensp
ENSP00000535859
resolver
ensp
ENSP00000741815
resolver
ensp
ENSP00000778424
resolver
enst
ENST00000464139
resolver
genesymbol
TUBGCP3
resolver
genesymbol_syn
GCP3
resolver
hgnc
HGNC:18598
resolver
uniprot
A0A087WU06
resolver
uniprot
B4DYP7
resolver
uniprot
O43631
resolver
uniprot
O60852
resolver
uniprot
O60853
resolver
uniprot
Q5T8L2
resolver
uniprot
Q7Z4K1
resolver
uniprot
Q96I79
resolver
uniprot_entry
A0A087WU06_HUMAN
resolver
uniprot_entry
B4DYP7_HUMAN
resolver
uniprot_entry
GCP3_HUMAN
resolver
uniprot_sec
O43631
resolver
uniprot_sec
O60852
resolver
uniprot_sec
O60853
resolver
uniprot_sec
Q5T8L2
resolver
uniprot_sec
Q7Z4K1
resolver
uniprot_sec
Q96I79
resolver
amino_acid_sequence
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSLLPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTGGTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWLHNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFDQIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHT
uniprot
proteins
function
FUNCTION: Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed:38305685, PubMed:38609661, PubMed:39321809, PubMed:9566967). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed:38305685, PubMed:38609661, PubMed:39321809). {ECO:0000269|PubMed:38305685, ECO:0000269|PubMed:38609661, ECO:0000269|PubMed:39321809, ECO:0000269|PubMed:9566967}.
uniprot
proteins
mass_dalton
103571
uniprot
proteins
protein_family
TUBGCP family
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057823
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17959831
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
38305685
uniprot
proteins
pubmed
38609661
uniprot
proteins
pubmed
39321809
uniprot
proteins
pubmed
9566967
uniprot
proteins
pubmed
9566969
uniprot
proteins
sequence_length
907
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843}.
uniprot
proteins