Cnot11
entrez
363221
canonical
uniprot
B0BNA9
canonical
ensembl
ENSRNOG00000023220
resolver
ensembl
ENSRNOG00055019862
resolver
ensembl
ENSRNOG00060025569
resolver
ensembl
ENSRNOG00065030569
resolver
ensp
ENSRNOP00000035943
resolver
ensp
ENSRNOP00055027569
resolver
ensp
ENSRNOP00060036694
resolver
ensp
ENSRNOP00065043303
resolver
enst
ENSRNOT00055033945
resolver
enst
ENSRNOT00060044250
resolver
enst
ENSRNOT00065052679
resolver
genesymbol
Cnot11
resolver
uniprot_entry
CNO11_RAT
resolver
amino_acid_sequence
MPGGGASTASGRLLSADPRGAREAAAFRSGPAGSSGGRGGAGGPGSGSGGPAGRMSLTPKELSSLLSIISEEAGGGSTFEGLSTAFHHYFSKADHFRLGSVLVMLLQQPDLLPSAAQRLTALYLLWEMYRTEPLAANPFAASFAHLLNPAPPARGGQEPDRPPLSGFLPPITPPEKFFLSQLMLAPPRELFKKTPRQIALMDVGNMGQSVDISGLQLALAERQSELPTQSKASFPSILSDPDPDSSNSAFDSSVASRITESLVSGPKPPIESHFRPEFIRPPPPLHICEDELAWLNPTEPEHAIQWDRSMCVKNSTGVEIKRIMAKAFKSPLSSPQQTQLLGELEKDPKLVYHIGLTPAKLPDLVENNPLVAIEMLLKLMQSSQITEYFSVLVNMDMSLHSMEVVNRLTTAVDLPPEFIHLYISNCISTCEQIKDKYMQNRLVRLVCVFLQSLIRNKIINVQDLFIEVQAFCIEFSRIREAAGLFRLLKTLDTGETPSETKVSK
uniprot
proteins
function
FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Does not seem to be required for complex deadenylase function (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
54836
uniprot
proteins
protein_family
CNOT11 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
504
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins