Commd3
entrez
12238
canonical
uniprot
Q63829
canonical
ensembl
ENSMUSG00000051154
resolver
ensp
ENSMUSP00000049882
resolver
enst
ENSMUST00000061158
resolver
genesymbol
Commd3
resolver
genesymbol_syn
Bup
resolver
uniprot
A2ASR4
resolver
uniprot
Q3UKI1
resolver
uniprot
Q8C9P5
resolver
uniprot_entry
COMD3_MOUSE
resolver
uniprot_sec
A2ASR4
resolver
uniprot_sec
Q3UKI1
resolver
uniprot_sec
Q8C9P5
resolver
amino_acid_sequence
MELSESVQRGIQTLADPGSFDSNAFALLLRAAFQSLLDARADEAALDHPYLKQIDPVVLKHCHAAAATCILEAGKHQVDKSTLSTYLEDCKFDRERIELFCTEYQNNKNSLETLLGSIGRSLPHITDVSWRLEYQIKTNQLHKMYRPGYLVTLNVENNDSQSYPEINFSCNMEQLQDLVGKLKDASKSLERATQL
uniprot
proteins
function
FUNCTION: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity). May down-regulate activation of NF-kappa-B (By similarity). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (By similarity). {ECO:0000250|UniProtKB:Q9UBI1}.
uniprot
proteins
mass_dalton
22037
uniprot
proteins
protein_family
COMM domain-containing protein 3 family
uniprot
proteins
pubmed
1287475
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
195
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9UBI1}. Nucleus {ECO:0000250|UniProtKB:Q9UBI1}.
uniprot
proteins