KLHL26
entrez
55295
canonical
uniprot
Q53HC5
canonical
ensembl
ENSG00000167487
resolver
ensp
ENSP00000300976
resolver
ensp
ENSP00000472001
resolver
ensp
ENSP00000472032
resolver
enst
ENST00000300976
resolver
enst
ENST00000595182
resolver
enst
ENST00000599006
resolver
genesymbol
KLHL26
resolver
hgnc
HGNC:25623
resolver
uniprot
M0R1N0
resolver
uniprot
M0R1P3
resolver
uniprot
Q8TAP0
resolver
uniprot
Q9NUX3
resolver
uniprot_entry
KLH26_HUMAN
resolver
uniprot_entry
M0R1N0_HUMAN
resolver
uniprot_entry
M0R1P3_HUMAN
resolver
uniprot_sec
Q8TAP0
resolver
uniprot_sec
Q9NUX3
resolver
amino_acid_sequence
MAESGGSSGGAGGGGAFGAGPGPERPNSTADKNGALKCTFSAPSHSTSLLQGLATLRAQGQLLDVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGQMATTFSLASLRESVDAFTFRHFLQIAEEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRPRASHVLCHIRFPLMQSSELVDSVQTLDIMVEDVLCRQYLLEAFNYQVLPFRQHEMQSPRTAVRSDVPSLVTFGGTPYTDSDRSVSSKVYQLPEPGARHFRELTEMEVGCSHTCVAVLDNFVYVAGGQHLQYRSGEGAVDACYRYDPHLNRWLRLQAMQESRIQFQLNVLCGMVYATGGRNRAGSLASVERYCPRRNEWGYACSLKRRTWGHAGAASGGRLYISGGYGISVEDKKALHCYDPVADQWEFKAPMSEPRVLHAMVGAGGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTSVSPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTDTDEWERDLHFPESFAGIACAPVLLPRAGTRR
uniprot
proteins
disease_involvement
DISEASE: Note=Defects in KLHL26 may be cause of autosomal dominant inheritance of Ebstein's anomaly and left ventricular non-compaction. {ECO:0000269|PubMed:31985165}.
uniprot
proteins
function
FUNCTION: May play a role in endo(sarco)plasmic reticulum (ER/SR) mitochondrial signaling (PubMed:37204873). May be part of the ubiquitin-proteasome system (UPS) and affect ubiquitination and degradation of target substrates in cardiomyocytes (PubMed:37204873). {ECO:0000269|PubMed:37204873}.
uniprot
proteins
mass_dalton
68139
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
31985165
uniprot
proteins
pubmed
37204873
uniprot
proteins
sequence_length
615
uniprot
proteins