Naca
entrez
17938
canonical
uniprot
P70670
canonical
uniprot
Q60817
canonical
ensembl
ENSMUSG00000061315
resolver
ensp
ENSMUSP00000073532
resolver
ensp
ENSMUSP00000089680
resolver
ensp
ENSMUSP00000194203
resolver
enst
ENSMUST00000073868
resolver
enst
ENSMUST00000092048
resolver
genesymbol
Naca
resolver
genesymbol_syn
Gm1878
resolver
uniprot
E9QMB1
resolver
uniprot
Q3THR6
resolver
uniprot
Q4FZL8
resolver
uniprot_entry
NACAM_MOUSE
resolver
uniprot_entry
NACA_MOUSE
resolver
uniprot_sec
E9QMB1
resolver
uniprot_sec
Q3THR6
resolver
uniprot_sec
Q4FZL8
resolver
amino_acid_sequence
MPGEATETVPATEQELPQPQAETAVLPMSSALKVAAVGQPGPTPPSSLGPQQSPIVTAHQPSPLPSSVSSTPFEVPFAQPITAETALPSGTAPPTPTFLPHLIGPPISPAALALASPMIGLAQKGARSSSAPLSLVALAPHSVQKSSVCPPHPLTSPPSAAGAELGALTASIPPLEPKTSTSQVPSQGTLNLKGTAPCPPDVVRAFPSHLENPLASVQPGLMSCPQTLSNTSPVKGVPISSALTQSRLSLNLKGPVSPPARNTAAPSIPLAPSTSLGCHLPLLHHSSVDSPIQPPGQSGLAVSNPTSVGHSGIAASCPPERCVVPALPSRLLAVDSGAAPSDDKGSSAVTNELCSPPGSSNVAGTSLSPKASLVPKGSNVALQPLVTQVPASQKTGLKEIPVSCIGATHHALDNPSAISVAPATHVPPPTSSGLVSSKDPASPVTSLVVPAAHKQFPAPPASATLGVPVSPLPATEGLKNLPISALVNVGAPVSPAQAGLPTRKDTTLQPLAPIALKESPSSQSASSLEVLSEDTVTKKTTGGPAPVVRPAIAGVATTTSLRADSPPAVIRADSCVSPNTVSQPLKRSVTDPAMAPRTAKNTAPSTTSPLVPLASEGCPVASSMALSPQNASVSETALALSPEIPKSVPFPDPPLAEISFSNARKVDAVSHMESSGSSRQGHPDASVTAKGTVVCLADSSLDTSVSASKGSALSGASSPLYPLEVSFLPEAGLAVQGPKGSLNKLSPTPPSSKGAPVPSTGAPPSPKGAPIVPTESSISSKQVPAEILPSPQKTPEVTASRLISAVQSPKVDPIMSDVTPTSPKKTSATAVPKDTSATLSLKSVPAVTSLSPPKAPVAPSNEATIVPTEIPTSLKNALAAATPKETLATSIPKVTSPSPQKTPKSVSLKGAPAMTSKKATEIAASKDVSPSQFPKEVPLLPHVPPTSPPKSPVSDTLSGALTSPPPKGPPATLAETPTYPKKSPKPAASKKTPATPSPEGVTAVPLEIPPCSKKAPKTAAPKESSATSSSKRAPKTAVSKEIPSKGVTAVPLEISLPLKETSKSATPGEKSASSPKRSPKTAGPKETPPGGVTAVPPEISLPPKETPQNATPNESLAASSQKRSPKTSVPKETPPGGVTAMPLEIPSAPQKAPKTAVPKQIPTPEDAVTILAGSPLSPKKASKTAAPKEAPATPSVGVIAVSGEISPSPKKTSKTAAPKENSATLPPKRSPKTAAPKETPATSSEGVTAVPSEISPSPPTPASKGVPVTLTPKGAPNALAESPASPKKVPKTAAPEETSTTPSPQKIPKVAGPKEASATPPSKKTPKTAVPKETSAPSEGVTAVPLEIPPSPRKAPKTAAPKETPAPSPEGATTAPVQIPPSPRKGSKKAGSKETPTTPSPEGVTAAPLEIPISSKKTSKMASPKETLVTPSSKKLSQTVGPKETSLEGATAVPLEIPPSHKKAPKTVDPKQVPLTPSPKDAPTTLAESPSSPKKAPKTAAPPSERVTTVPPEKPATPQKASATTASKVPVPAETQEVAVSSRETPVTPAVPPVKNPSSHKKTSKTIELKEAPATLPPSPTKSPKIPSSKKAPRTSAPKEFPASPSIKPVTTSLAQTAPPSLQKAPSTTIPKENLAAPAVLPVSSKSPAAPAAASASLSPATAAPQTAPKEATTIPSCKKAAATETPIETSTAPSLEGAPKETSETSVSKVLMSSPPKKASSSKRASTLPATTLPSLKEASVLSPTATSSGKDSHISPVSDACSTGTTTPQASEKLPSKKGPTAFTEMLAAPAPESALAITAPIQKSPGANSNSASSPKCPDPSSKKDTKGLPSAVALAPQTVPVEKDTSKAIETLLVSPAKGSDCLHSPKGPVGSQVATPLAAFTSDKVPPEAVSASVAPKPAPAASLTLAPSPVAPLPPKQPLLESAPGSVLESPSKLPVPAEEDELPPLIPPEAVSGGEPFQPILVNMPAPKPAGTPAPAPSAKQPVLKNNKGSGTESDSDESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM
uniprot
proteins
amino_acid_sequence
MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM
uniprot
proteins
function
FUNCTION: Cardiac- and muscle-specific transcription factor. May act to regulate the expression of genes involved in the development of myotubes. Plays a critical role in ventricular cardiomyocyte expansion and regulates postnatal skeletal muscle growth and regeneration. Involved in the organized assembly of thick and thin filaments of myofibril sarcomeres. {ECO:0000269|PubMed:21071677, ECO:0000269|PubMed:23662692, ECO:0000269|PubMed:8698236}.
uniprot
proteins
function
FUNCTION: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity). Isoform 1 and isoform 2 appear to bind DNA and play roles in transcription. Isoform 1 may function as a specific coactivator for JUN, acting to stabilize the interaction of JUN homodimers with promoter elements. {ECO:0000250, ECO:0000269|PubMed:15299025, ECO:0000269|PubMed:15831452, ECO:0000269|PubMed:8698236, ECO:0000269|PubMed:9488445, ECO:0000269|PubMed:9488446}.
uniprot
proteins
mass_dalton
220499
uniprot
proteins
mass_dalton
23384
uniprot
proteins
mutagenesis
MUTAGEN 1952; /note="L->A: Loss of interaction with SMYD1."; /evidence="ECO:0000269|PubMed:12011100
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Ser-2015 by ILK during cell adhesion may promote nuclear localization. Phosphorylation of Thr-2131 by GSK3B may promote proteasome mediated degradation.
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Ser-43 by ILK during cell adhesion may promote nuclear localization. Phosphorylation of Thr-159 by GSK3B may promote proteasome mediated degradation. {ECO:0000269|PubMed:15005626, ECO:0000269|PubMed:15299025}.
uniprot
proteins
protein_family
NAC-alpha family
uniprot
proteins
pubmed
10224091
uniprot
proteins
pubmed
12011100
uniprot
proteins
pubmed
15005626
uniprot
proteins
pubmed
15299025
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15831452
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21071677
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23662692
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
8698236
uniprot
proteins
pubmed
9488445
uniprot
proteins
pubmed
9488446
uniprot
proteins
pubmed
9877153
uniprot
proteins
sequence_length
215
uniprot
proteins
sequence_length
2187
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12011100}. Nucleus {ECO:0000269|PubMed:12011100}.
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus. {ECO:0000250}.
uniprot
proteins