Klf13
entrez
50794
canonical
uniprot
Q9JJZ6
canonical
ensembl
ENSMUSG00000052040
resolver
ensp
ENSMUSP00000067680
resolver
enst
ENSMUST00000063694
resolver
genesymbol
Klf13
resolver
genesymbol_syn
Bteb3
resolver
genesymbol_syn
Fklf2
resolver
uniprot
Q9ESX3
resolver
uniprot
Q9JHF8
resolver
uniprot_entry
KLF13_MOUSE
resolver
uniprot_sec
Q9ESX3
resolver
uniprot_sec
Q9JHF8
resolver
amino_acid_sequence
MAAAAYVDHFAAECLVSMSSRAVVHEPREGPEPRPEGAAAAAPTLPRVDERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPAPPAPPPGPEPASPGQAGAPAAPPSPAWSEPEAALEQEPGPAGSGEPGLRQRGRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQECNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRHANFHPGMLQRRGGGSRTGSLSDYSRSDASSPTISPASSP
uniprot
proteins
function
FUNCTION: Transcription factor that activates expression from GC-rich minimal promoter regions, including genes in the cells of the erythroid lineage (PubMed:10642511, PubMed:10828046). Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES and CCL5 expression in T-cells (By similarity). {ECO:0000250|UniProtKB:Q9Y2Y9, ECO:0000269|PubMed:10642511, ECO:0000269|PubMed:10828046}.
uniprot
proteins
mass_dalton
31136
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PRP4K; phosphorylation regulates its transcriptional modulator activity. {ECO:0000250|UniProtKB:Q9Y2Y9}.
uniprot
proteins
protein_family
Sp1 C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
10642511
uniprot
proteins
pubmed
10828046
uniprot
proteins
pubmed
11087666
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
289
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y2Y9}.
uniprot
proteins