PARPBP
entrez
55010
canonical
uniprot
Q9NWS1
canonical
ensembl
ENSG00000185480
resolver
ensp
ENSP00000332915
resolver
ensp
ENSP00000376643
resolver
ensp
ENSP00000393867
resolver
ensp
ENSP00000411313
resolver
ensp
ENSP00000440850
resolver
ensp
ENSP00000442549
resolver
ensp
ENSP00000444576
resolver
ensp
ENSP00000522279
resolver
ensp
ENSP00000522280
resolver
ensp
ENSP00000522281
resolver
ensp
ENSP00000599828
resolver
ensp
ENSP00000599829
resolver
ensp
ENSP00000599831
resolver
ensp
ENSP00000638057
resolver
ensp
ENSP00000638058
resolver
ensp
ENSP00000653558
resolver
ensp
ENSP00000653559
resolver
ensp
ENSP00000724422
resolver
ensp
ENSP00000724423
resolver
ensp
ENSP00000750489
resolver
ensp
ENSP00000750490
resolver
ensp
ENSP00000750493
resolver
ensp
ENSP00000750494
resolver
ensp
ENSP00000750499
resolver
ensp
ENSP00000786087
resolver
ensp
ENSP00000787004
resolver
ensp
ENSP00000800435
resolver
enst
ENST00000541394
resolver
enst
ENST00000543784
resolver
genesymbol
PARPBP
resolver
genesymbol_syn
C12orf48
resolver
genesymbol_syn
PARI
resolver
hgnc
HGNC:26074
resolver
uniprot
B4DT40
resolver
uniprot
B4DZ31
resolver
uniprot
B4E0Y0
resolver
uniprot
F6T824
resolver
uniprot
F6VL08
resolver
uniprot
Q05C00
resolver
uniprot
Q499L8
resolver
uniprot
Q4FZA0
resolver
uniprot
Q4KMW7
resolver
uniprot
Q6NSC6
resolver
uniprot
Q6PJA1
resolver
uniprot
Q86W36
resolver
uniprot
Q9BZU5
resolver
uniprot_entry
B4DT40_HUMAN
resolver
uniprot_entry
B4DZ31_HUMAN
resolver
uniprot_entry
F6T824_HUMAN
resolver
uniprot_entry
F6VL08_HUMAN
resolver
uniprot_entry
PARI_HUMAN
resolver
uniprot_entry
Q9BZU5_HUMAN
resolver
uniprot_sec
B4E0Y0
resolver
uniprot_sec
Q05C00
resolver
uniprot_sec
Q499L8
resolver
uniprot_sec
Q4FZA0
resolver
uniprot_sec
Q4KMW7
resolver
uniprot_sec
Q6NSC6
resolver
uniprot_sec
Q6PJA1
resolver
uniprot_sec
Q86W36
resolver
amino_acid_sequence
MAVFNQKSVSDMIKEFRKNWRALCNSERTTLCGADSMLLALQLSMAENNKQHSGEFTVSLSDVLLTWKYLLHEKLNLPVENMDVTDHYEDVRKIYDDFLKNSNMLDLIDVYQKCRALTSNCENYNTVSPSQLLDFLSGKQYAVGDETDLSIPTSPTSKYNRDNEKVQLLARKIIFSYLNLLVNSKNDLAVAYILNIPDRGLGREAFTDLKHAAREKQMSIFLVATSFIRTIELGGKGYAPPPSDPLRTHVKGLSNFINFIDKLDEILGEIPNPSIAGGQILSVIKMQLIKGQNSRDPFCKAIEEVAQDLDLRIKNIINSQEGVVALSTTDISPARPKSHAINHGTAYCGRDTVKALLVLLDEEAANAPTKNKAELLYDEENTIHHHGTSILTLFRSPTQVNNSIKPLRERICVSMQEKKIKMKQTLIRSQFACTYKDDYMISKDNWNNVNLASKPLCVLYMENDLSEGVNPSVGRSTIGTSFGNVHLDRSKNEKVSRKSTSQTGNKSSKRKQVDLDGENILCDNRNEPPQHKNAKIPKKSNDSQNRLYGKLAKVAKSNKCTAKDKLISGQAKLTQFFRL
uniprot
proteins
function
FUNCTION: Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect. {ECO:0000269|PubMed:20931645, ECO:0000269|PubMed:22153967}.
uniprot
proteins
mass_dalton
65054
uniprot
proteins
protein_family
PARI family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
20931645
uniprot
proteins
pubmed
22153967
uniprot
proteins
sequence_length
579
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20931645, ECO:0000269|PubMed:22153967}. Note=Localizes to chromatin in response to S phase arrest but not in mitosis. Targeted to chromatin via its interaction with PCNA.
uniprot
proteins