Tnfrsf8
entrez
21941
canonical
uniprot
Q60846
canonical
ensembl
ENSMUSG00000028602
resolver
ensp
ENSMUSP00000030339
resolver
enst
ENSMUST00000030339
resolver
genesymbol
Tnfrsf8
resolver
uniprot
A1L3C9
resolver
uniprot_entry
TNR8_MOUSE
resolver
uniprot_sec
A1L3C9
resolver
amino_acid_sequence
MSALLTAAGLLFLGMLQAFPTDRPLKTTCAGDLSHYPGEAARNCCYQCPSGLSPTQPCPRGPAHCRKQCAPDYYVNEDGKCTACVTCLPGLVEKAPCSGNSPRICECQPGMHCCTPAVNSCARCKLHCSGEEVVKSPGTAKKDTICELPSSGSGPNCSNPGDRKTLTSHATPQAMPTLESPANDSARSLLPMRVTNLVQEDATELVKVPESSSSKAREPSPDPGNAEKNMTLELPSPGTLPDISTSENSKEPASTASTLSLVVDAWTSSRMQPTSPLSTGTPFLDPGPVLFWVAMVVLLVGSGSFLLCYWKACRRRFQQKFHLDYLVQTFQPKMEQTDSCPTEKLTQPQRSGSVTDPSTGHKLSPVSPPPAVETCASVGATYLENLPLLDDSPAGNPFSPREPPEPRVSTEHTNNRIEKIYIMKADTVIVGSVKTEVPEGRAPAGSTESELEAELEVDHAPHYPEQETEPPLGSCTEVMFSVEEGGKEDHGPTTVSEK
uniprot
proteins
function
FUNCTION: Receptor for TNFSF8/CD30L (PubMed:8543792). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity). {ECO:0000250|UniProtKB:P28908, ECO:0000269|PubMed:8543792}.
uniprot
proteins
mass_dalton
53216
uniprot
proteins
protein_family
TNFR8 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8543792
uniprot
proteins
sequence_length
498
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:8543792}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins