KIF25
entrez
3834
canonical
uniprot
Q9UIL4
canonical
ensembl
ENSG00000125337
resolver
ensp
ENSP00000496229
resolver
ensp
ENSP00000625812
resolver
genesymbol
KIF25
resolver
genesymbol_syn
KNSL3
resolver
hgnc
HGNC:6390
resolver
uniprot
A8K0C3
resolver
uniprot
O94775
resolver
uniprot
Q5SZU9
resolver
uniprot_entry
KIF25_HUMAN
resolver
uniprot_sec
A8K0C3
resolver
uniprot_sec
O94775
resolver
uniprot_sec
Q5SZU9
resolver
amino_acid_sequence
MTWTSGQLQREKQARPGSGAVLAFPDDKDLRVYGPAESQSAVFGDVCPLLTSLLDGYNVCVMAYGQTGSGKSYTMLGRHSDDGPVLPLDPQSDLGIIPRVAEELFRLILENTSRSPKVEVSIVEVYNNDIFDLLAKDSIAAVSGVKREVVTAKDGRTEVALLASEAVGSASKLMELVHGGLQLRAKHPTLVHADSSRSHLIITVTLTTASCSDSTADQACSATLPREQTEAGRAGRSRRASQGALAPQLVPGNPAGHAEQVQARLQLVDSAGSECVGVSGVTGLALREMACISRSLAALAGVLGALLEHRGHAPYRNSRLTHLLQDCLGGDAKLLVILCISPSQRHLAQTLQGLGFGIRARQVQRGPARKKPPSSQTEGKRRPD
uniprot
proteins
function
FUNCTION: Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase (PubMed:28263957). Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis (PubMed:28263957). May also act as a negative regulator of amino acid starvation-induced autophagy (PubMed:22354037). {ECO:0000250|UniProtKB:Q4R918, ECO:0000269|PubMed:22354037, ECO:0000269|PubMed:28263957}.
uniprot
proteins
mass_dalton
40686
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
22354037
uniprot
proteins
pubmed
28263957
uniprot
proteins
pubmed
9925916
uniprot
proteins
sequence_length
384
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q4R918}.
uniprot
proteins