Dnmbp
entrez
71972
canonical
uniprot
Q6TXD4
canonical
ensembl
ENSMUSG00000025195
resolver
ensp
ENSMUSP00000026209
resolver
ensp
ENSMUSP00000148421
resolver
ensp
ENSMUSP00000148546
resolver
ensp
ENSMUSP00000148582
resolver
ensp
ENSMUSP00000148708
resolver
enst
ENSMUST00000026209
resolver
enst
ENSMUST00000212032
resolver
enst
ENSMUST00000212396
resolver
enst
ENSMUST00000212592
resolver
genesymbol
Dnmbp
resolver
genesymbol_syn
Kiaa1010
resolver
genesymbol_syn
Tuba
resolver
uniprot
A0A0R4J055
resolver
uniprot
A0A1D5RLL6
resolver
uniprot
A0A1D5RMB5
resolver
uniprot
Q6ZQ05
resolver
uniprot
Q8CEW8
resolver
uniprot
Q8R0Y2
resolver
uniprot
Q9CWU8
resolver
uniprot_entry
A0A0R4J055_MOUSE
resolver
uniprot_entry
A0A1D5RLL6_MOUSE
resolver
uniprot_entry
A0A1D5RMB5_MOUSE
resolver
uniprot_entry
DNMBP_MOUSE
resolver
uniprot_entry
Q9CWU8_MOUSE
resolver
uniprot_sec
Q6ZQ05
resolver
uniprot_sec
Q8CEW8
resolver
uniprot_sec
Q8R0Y2
resolver
amino_acid_sequence
MEPGSMVRAIFDFCPSVSEELPLFVGDVIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFVSRELNSLSLHRGDLVILDDSAPTAGWLQGRSCWGAWGFFPSSCVQELCLSSRSRRWHAQSALLQAPEYSLGQARALMGLSAQLDEELDFREGDLITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTVDESVNSRSGDDSAVNGEVDVPPEEAESGGDEDDQQSGTYGIALYRFQALETNELDFEVGDRIQILGTLEDGWLEGCLKGKTGVFPHRFVKLCPSNRTEETTAQPQESSFPKDSESSVGKSGDSVVEEARQEPWECEEERPDYDLPGQASVPQDHVAPEWTGDTISGQDKDASGSSPDVDLERPLAKDLSTPDPSEEVNGVSSQPQVPIHPKVQKSQHYLTAGGSHQTSDPFSELVPLEARTRDYSSLPPRRTYAQGWSFQKPASHLQRASSLTASRLDRPSHFCHPAMASYAQKHQTSTENTASLHDPPERPERRPGLQDRGPATDITTASQGDSLDLDSKLTQQLIEFEKSLSGPSTEPETIVRRFSIMDFYSEKDIVRGSSNSLPSQAFPERRKTLRPPPPRPRTPTPISSHLLVDQSPKPVPTLVVRPSRPAPLPPPAQQRMNTASPKPTSCAHPGWEAPEKEDSEHMEKSPAQTFPCPSMLARIRDVEQDLDTCTRAQEELNLLLEEKQDDPSRAETLETLRSYESTIQSLTLELQQLRDMTLLSSQSSSLAAPFGSVSTENPEQRMLEKRAKVVAELLQTERDYIRDLEMCIERVMVPLQQAQVPNVDFEGLFGNMQTVIKVSKQLLAALEISDAVGMSSCDCLVPGPVFLDHRDELEGTYRVYCQNHDEAISLLEMYEKDEKTQKHLQDYLADLKGCTNYINLGSFLIKPVQRIMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSSRVSSHLKHLTGFAPQLKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAMSIWDLCMERGHHDLEQFEKVHRYISDQLFTRFKERTERLVINPLNQLLNMFTGPYKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNSQLLDELPKFQQYAQSLFTNCIHGYAEAHCDFVQQALEQLQPLLSLLKATDREGNLIAIFLEEHSRVLQQLQVFTFFPESLPAPRKPFERKTTDRQSSRKTLLGMPSYMLQSEELRSSLLARYPPEKLFHVQRNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLVDNGVTKGFVYSSFLKPYNPRCSHSDASVASHSSTESEHSGSSPGCHRQNSHSALTFNSNNMTVSFTSGLALTQPQDASPLKDCAHETLAVSWNTGHPETGPSTCSSDPGFSCQRRLGNPADGARDISQPASTLRGCQRSSPHSEVVGYSVPGRNDQGSDSIKGSARVCQAPEDRDRGVGSSETEGNQVYFAIYTFKARNPNELSVLANQRLRIHEFKDVTGNTEWWLAEVNGRKGYVPSNYIRKTEYT
uniprot
proteins
function
FUNCTION: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions in epithelial cells (By similarity). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation (By similarity). Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (PubMed:14506234). {ECO:0000250|UniProtKB:E2RP94, ECO:0000250|UniProtKB:Q6XZF7, ECO:0000269|PubMed:14506234}.
uniprot
proteins
mass_dalton
177277
uniprot
proteins
pubmed
14506234
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1580
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14506234}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:14506234}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14506234}. Synapse {ECO:0000250|UniProtKB:M0R4F8}. Cell junction {ECO:0000250|UniProtKB:Q6XZF7}. Note=Localizes to the apical junction, colocalizes with TJP1. {ECO:0000250|UniProtKB:Q6XZF7}.
uniprot
proteins