Tgfa
entrez
21802
canonical
uniprot
P48030
canonical
ensembl
ENSMUSG00000029999
resolver
ensp
ENSMUSP00000032066
resolver
enst
ENSMUST00000032066
resolver
genesymbol
Tgfa
resolver
uniprot
Q545E4
resolver
uniprot_entry
Q545E4_MOUSE
resolver
uniprot_entry
TGFA_MOUSE
resolver
amino_acid_sequence
MVPATGQLALLALGILLAVCQALENSTSPLSDSPVAAAVVSHFNKCPDSHTQYCFHGTCRFLVQEEKPACVCHSGYVGVRCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVLIHCCQLRKHCEWCRALVCRHEKPSALLKGRTACCHSETVV
uniprot
proteins
function
FUNCTION: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
uniprot
proteins
mass_dalton
17018
uniprot
proteins
pubmed
1420315
uniprot
proteins
pubmed
15652357
uniprot
proteins
pubmed
8877107
uniprot
proteins
sequence_length
159
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Transforming growth factor alpha]: Secreted, extracellular space.; SUBCELLULAR LOCATION: [Protransforming growth factor alpha]: Cell membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 98..123; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins