E0CZ42
uniprot
E0CZ42
canonical
amino_acid_sequence
MFGLKLKKKKKDKAEKGLVLTNKGAQDGNESEIPQKGPSHQEGPEDLTKDDAFLAPGPSAPSKRRAKLLTKIHDGEIKSQNYQITVTITEARQLVGENIDPVVTIEIGDDKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKISVLHHKLIGSILIGSFRVDVGTVYNQPGHQFCDKWALLTDPGDIRTGTKGYLKCDISVTGKGDILKTNPKTSDAEEQIEKNLLIPQGFPSERPWARFYVRLYRAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQTGRTSVQKNCADPVWHEQVVFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKISNEQDGDKGFLPTFGPAWINLYGSPRNHSLMDDYQELNEGFGEGVSFRGRILVEIAVEILSGGAQESKFSKALKELKLSSKDKDSKSSKGSSKDKADKADDSKAQQTTDKTNSTEVEVESFAVPPEIIPEKYEDFLLFGAFFEATMIDRKIGDKPISFEVSVGNFGNLIDGGSHHGSKKKSTELTEEDVLPLLHEGEKDVAQDSAISMASTTHPEKPLVTDGNRNYNYLPFGAKKPCVSFISSWGDQTFRLHWSNMLEKMADLLEEGIEEVRELVKVSQEAPEEKMKTALRDFITQSRVFISEAEKKPKTLNQTALDKKRLTLCWQELKAMADEAEGVIRQQKKKLSLDEMIREAQNFVEKIHFLVDEPQHTIPDVFIWMLSNNKRVAYARIAAKDLLYSPIEEQMGKHCGKIKTHFLKLPGKRPPGWTVQAKVDIYLWLGSTRYSNTILDNLPVGYEAEMPPKSSGTHHPPSALLYQAQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSQCQTTKIISQTLSPTWNQMLLFNELVLHGEEKELLESPPHVVVELYDSDAVGKPEYLGATVAAPVVTLADQDYEPPKLSYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLPPTGPPDITQIYPVPSNIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQVLIECGGGGVKSCVIQSYKNNPNFSVQAEAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTINCLKQFLCKPRETFALTSQTDGDGARPAISDSLAATESSNLLSSSQDLPADHVYVDVEPPPTMLPDSAQAQTATLVDIPDSSPMLETEHKPVAQGPPKDGHGKDPRKPSRRSTKRRRRTIADESAENVIDWWSKYYASVKRAQKEKENNHKEKRATEAKPDEVVLDMEDGPKRKKDKMLKKKLKDDGNDAIPNLAALKIYDGDLESEFNNFEDWVKTFELFRGKSTEEDHGLDGDRVIGKFKGSFCIYKSPEDSTSEDSGQLRIQQGIPPNHPVQVLIRVYIVAAFNLSPADPDGKSDPYIVLRLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSVLIYDHDMIGSDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFRPGKIQIGKKVFSGKTVFNEEDSEEMVESYEHLALKVLHSWEDIPEAGWRLVPEHIETRPLYHKDKPGMEQGRLQMWVDMFPKDTPQLGPPVDISPRKPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWIKGLEDDRQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVISKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGSLEMNLNSFPRAAKSAKACDLSKFENAVQENKISIFQQKRVRGWWPFAKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFVSPFKCLYHLIWKNYKKYIIIAFILIILIVFLVLFIYTLPGAISRRIVVGGS
uniprot
proteins
function
FUNCTION: Calcium/phospholipid-binding protein which is essential for proper development of skeletal and cardiac muscle. {ECO:0000250|UniProtKB:A0AB32U2W5}.
uniprot
proteins
mass_dalton
209831
uniprot
proteins
protein_family
Ferlin family
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
30516436
uniprot
proteins
sequence_length
1862
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:30516436}; Single-pass type IV membrane protein {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:30516436}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q2WGJ9}. Recycling endosome {ECO:0000250|UniProtKB:Q2WGJ9}. Note=Shuttles from the cell membrane to a distinct subcompartment of the trans-Golgi network that is closely associated with the recycling endosome. {ECO:0000250|UniProtKB:Q2WGJ9}.
uniprot
proteins
transmembrane_region
TRANSMEM 1829..1849; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins