Atp6v0e1
entrez
94170
canonical
uniprot
Q794C0
canonical
ensembl
ENSRNOG00000003269
resolver
ensembl
ENSRNOG00055003132
resolver
ensembl
ENSRNOG00060003470
resolver
ensembl
ENSRNOG00065011116
resolver
ensp
ENSRNOP00000080976
resolver
ensp
ENSRNOP00055003585
resolver
ensp
ENSRNOP00060004157
resolver
ensp
ENSRNOP00065013719
resolver
enst
ENSRNOT00000097009
resolver
enst
ENSRNOT00055004858
resolver
enst
ENSRNOT00060005699
resolver
enst
ENSRNOT00065017995
resolver
genesymbol
Atp6v0e1
resolver
genesymbol_syn
Atp6v0e
resolver
genesymbol_syn
Dsr1
resolver
uniprot_entry
VA0E1_RAT
resolver
amino_acid_sequence
MAYHGLTVPLIVMSVFWGFVGLLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQLNPLFGPQLKNETIWYLKYHWP
uniprot
proteins
function
FUNCTION: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it promotes acidification of the extracellular environment (By similarity). The V-ATPase complex also acts as an activator for mTORC1 on lysosomal membrane by promoting the guanine nucleotide exchange factor (GEF) of the Ragulator complex, thereby enabling mTORC1 recruitment (By similarity). {ECO:0000250|UniProtKB:O15342, ECO:0000250|UniProtKB:Q2KIB5}.
uniprot
proteins
mass_dalton
9340
uniprot
proteins
protein_family
V-ATPase e1/e2 subunit family
uniprot
proteins
pubmed
11162653
uniprot
proteins
sequence_length
81
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 36..56; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins