Abcf1
entrez
85493
canonical
uniprot
Q6MG08
canonical
ensembl
ENSRNOG00000000799
resolver
ensp
ENSRNOP00000001049
resolver
genesymbol
Abcf1
resolver
genesymbol_syn
Abc50
resolver
uniprot
Q9ERQ2
resolver
uniprot_entry
ABCF1_RAT
resolver
uniprot_sec
Q9ERQ2
resolver
amino_acid_sequence
MPKGPKQQPPEPEWIGDGEGTSPADKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKLQKEKEQQQQQQQQKKKRDTRKGRRKKDVDDDDDGDERVLMERLKQLSVPASDEEDEVPVPVPRGRKKAKGGNVFEALIQDESEEEKEEEEEKPVLKPAKPEKNRINKAVAEEPPGLRNKKGKEEKSKGKAKNKPSATDSEGEDDEDMTKEKEPPRPGKDKDKKGAEQGSEEEKEEKEGEVKANDPYAHLSKKEKKKLKKQMDYERQVESLKAANAAENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLRLLEEEKRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQDPPELLKRPREYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEALGEVMVNRPRD
uniprot
proteins
function
FUNCTION: Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity). {ECO:0000250, ECO:0000269|PubMed:10931828}.
uniprot
proteins
mass_dalton
95252
uniprot
proteins
post_translational_modification
PTM: Phosphorylated at phosphoserine and phosphothreonine. Phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
10931828
uniprot
proteins
pubmed
15060004
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
839
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8NE71}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q8NE71}. Nucleus envelope {ECO:0000250|UniProtKB:Q8NE71}.
uniprot
proteins