Mblac1
entrez
304346
canonical
uniprot
Q6AYD1
canonical
ensembl
ENSRNOG00000082402
resolver
ensp
ENSRNOP00000104063
resolver
ensp
ENSRNOP00000106336
resolver
ensp
ENSRNOP00000112777
resolver
enst
ENSRNOT00000129882
resolver
enst
ENSRNOT00000132761
resolver
enst
ENSRNOT00000144546
resolver
genesymbol
Mblac1
resolver
uniprot_entry
MBLC1_RAT
resolver
amino_acid_sequence
MSGPVRTEPLHGETPLLASSGSYSVVVLLRGYAEPQGVGDAVRADGTVTLVLPRGWVSDTSRRLAPSADGGAKTALEEAVRGPILVDTGGPWTRDALLEALATQGVAPGDVTLVVGTHGHSDHIGNLGLFPQAALLVSHDFCLPGGLYLPHGLCETQPLILGSGLQVWATPGHGGQRDVSVVVEGTSLGTVVVVGDVFERLGDEDSWQDLSEDPVAQQRSRERILSVADVVVPGHGAPFRVVREAVKSSED
uniprot
proteins
ec_number
3.1.27.-
uniprot
proteins
function
FUNCTION: Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end. Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase. Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop. May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage. {ECO:0000250|UniProtKB:A4D2B0}.
uniprot
proteins
mass_dalton
26137
uniprot
proteins
protein_family
Glyoxalase II family
uniprot
proteins
protein_family
Metallo-beta-lactamase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
251
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:A4D2B0}. Nucleus {ECO:0000250|UniProtKB:A4D2B0}. Note=Localizes in the nucleus during early S-phase of the cell cycle. {ECO:0000250|UniProtKB:A4D2B0}.
uniprot
proteins