Mvd
entrez
192156
canonical
uniprot
Q99JF5
canonical
ensembl
ENSMUSG00000006517
resolver
ensp
ENSMUSP00000006692
resolver
enst
ENSMUST00000006692
resolver
genesymbol
Mvd
resolver
uniprot
Q3TCD8
resolver
uniprot
Q3UYC1
resolver
uniprot
Q8BTM4
resolver
uniprot
Q922D7
resolver
uniprot_entry
MVD1_MOUSE
resolver
uniprot_entry
Q3UYC1_MOUSE
resolver
uniprot_sec
Q3TCD8
resolver
uniprot_sec
Q8BTM4
resolver
uniprot_sec
Q922D7
resolver
amino_acid_sequence
MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTVAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTEDGDTLPLSLSYKVHVASVNNFPTAAGLASSAAGYACLAYTLAQVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRILILVVSADKKQTGSTVGMQTSVETSTLLKFRAESVVPERMKEMTRCIQEQDFQGFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNTHQGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKAALAVEPSPGGVQYIIATQVGPGPQVLDDTHDHLLGQDGLPQRDL
uniprot
proteins
ec_number
4.1.1.33
uniprot
proteins
function
FUNCTION: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. {ECO:0000250|UniProtKB:P53602}.
uniprot
proteins
mass_dalton
44072
uniprot
proteins
pathway_participation
PATHWAY: Steroid biosynthesis; cholesterol biosynthesis. {ECO:0000305}.
uniprot
proteins
protein_family
Diphosphomevalonate decarboxylase family
uniprot
proteins
pubmed
12736493
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
401
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12736493}.
uniprot
proteins