Pinx1
entrez
72400
canonical
uniprot
Q9CZX5
canonical
ensembl
ENSMUSG00000021958
resolver
ensp
ENSMUSP00000022528
resolver
ensp
ENSMUSP00000258242
resolver
enst
ENSMUST00000022528
resolver
genesymbol
Pinx1
resolver
genesymbol_syn
Lpts
resolver
uniprot
Q14BS4
resolver
uniprot
Q3V450
resolver
uniprot
Q8C6E5
resolver
uniprot
Q91WZ9
resolver
uniprot
Q9D0C2
resolver
uniprot_entry
PINX1_MOUSE
resolver
uniprot_sec
Q14BS4
resolver
uniprot_sec
Q3V450
resolver
uniprot_sec
Q8C6E5
resolver
uniprot_sec
Q91WZ9
resolver
uniprot_sec
Q9D0C2
resolver
amino_acid_sequence
MSMLAERRRKQKWTVDPRNTAWSNDDSKFGQKMLEKMGWSKGKGLGAQEQGATEHIKVKVKNNHLGLGATNNNEDNWIAHQDDFNQLLAALNTCHGQETADSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKDLSSRSETDLDCIFGKRRNKKLAQDGCSNSSADEVNTSLTTTTTTTSAFTIQEYFAKRMAQLKNKPQASAPGSDLSETPVERKKGKKKNKEAADTDVENSPQHKAKRHKKKKRVEAERGPVAKKRDRAELQPGGPSEDECSDASVEAAEDCVQTPDIQDDVPKPKKRKAKKKLQRPEGVEIDATLDRAPVKKKKKKVSR
uniprot
proteins
function
FUNCTION: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
37221
uniprot
proteins
protein_family
PINX1 family
uniprot
proteins
pubmed
11701125
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Chromosome, telomere {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE (By similarity). {ECO:0000250}.
uniprot
proteins