Focad
entrez
230393
canonical
uniprot
A2AKG8
canonical
ensembl
ENSMUSG00000038368
resolver
ensp
ENSMUSP00000095602
resolver
ensp
ENSMUSP00000124298
resolver
ensp
ENSMUSP00000210933
resolver
ensp
ENSMUSP00000210937
resolver
ensp
ENSMUSP00000210947
resolver
enst
ENSMUST00000159342
resolver
genesymbol
Focad
resolver
genesymbol_syn
BC057079
resolver
genesymbol_syn
Kiaa1797
resolver
uniprot
E9PYJ6
resolver
uniprot
Q0P620
resolver
uniprot
Q3TPY9
resolver
uniprot
Q3UJY8
resolver
uniprot
Q3UK73
resolver
uniprot
Q6PGE3
resolver
uniprot_entry
E9PYJ6_MOUSE
resolver
uniprot_entry
FOCAD_MOUSE
resolver
uniprot_sec
Q0P620
resolver
uniprot_sec
Q3TPY9
resolver
uniprot_sec
Q3UJY8
resolver
uniprot_sec
Q3UK73
resolver
uniprot_sec
Q6PGE3
resolver
amino_acid_sequence
MSDDIKKRFDFPNSLIQSQAVGHLIAAVLKEHGVSEKIHQSTNQTAALNLLWEKCCSDHVVVRTACSEGLVALVAQGHAEFSYVLNGILNLTPSARNMSGLIKALMKLLQMQALREGQSGEKDIQDIYSIRNPPQPLITVLEHRPDCWPLLLQQLTAFFQQCPERSEASCVQIMAPFLWYLYCEPSQLEEYAKLRLSLLKVLLQPRGVCEEAQLSVREQSTLQLCCSMLPCLQMKDLMQTTEMMLFVEEVYLSLLRHPGFWKSQLTQLTLQLLCICEVSLKITGECSSLIHLLERSVELLGEDFPVELVIIGIALLLLQMPASQQKPLLNLALKLLSLTEGQKIPKASLLLLVPLLQILSSTALEDCLAMGEEGPSRQQLALSLVEVLQKERHGDDSHTISCRLAFPVSSMYGSIFTAWRILDVIGEESATSDWLATVESLLSATTVIPPHVFLLLAYLLVEDVGQNLQQILRVTTQLAQADSSQVPNLIPVLMFKLGRPLDPVSYNHILYTLPTLGVHKVCVGQILRVIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAVSDAPSLSVGKELQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDMRPLILKTLSELFSLVPSLTVNTVEYENFKVQVLSFLWTHTQNKNPTVASAAYKSLSHFSAGEHTILHLPEKIRPEMPVPGELDEEESVDLSIPGACFLRLLTITAPSVLPALEEFFTSLVRQEMVNMPRGIYHSALKGGVRSDQGKTVAGIPNFILKTYETNKQPGLKPGLAGGMLFCYDLAMYQSKDGKPLNRLMASRGRSFKQTTLALIHEVHVQLSEWHRAIFLPQAWLAYMTRAYHAILQGRIAELELQLQHGKEGPEEVQYKRSTAWLWVRDMLTDEITKTAAKESPVVKANALLALSSLAVVVSKHEASLCSDSDGVLEIQPNFLPVKEWVSMVLNTLLVIVDSHYHPSGQLFTCFYHKSYSGENTASAIARSAAATALSLLVPVFIISCKEKVEEILNMLTARLPGKPSADESQAVQIHMGLALGMFLSRLCEEKLSDMSGQQMNLLLMKSLDALESCCFDPSLEYNTGCILGVGLALSLMSHSSHTESRVHVAASLRKLSTYLDESGSQSRTFQEVLVYTLSCVCTSAFSAGIIEAAEAEDIMSKLQLLVENNQQTSGFALALGNLVYGLSVCGHGKAEDLGNRLRPSWIKVVLTEGAPTMLCLAALHGLVALVGSDVDVMQLKSEAIQNTHFQARLNEVIRTLTEVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPEGSFIRAAIGFFITGGKKGPEAVPPSLLKVVMKPIATVGESYQYPPANLAALLSPLMRLNFGEEIQQLCLEIAVTQAPSSQSAASLLGLWVMPPLIHGLSLNIKKYLLVSMPLWAKHVSDEQIQGFVENLMVEVFKTASQPCHPEMCLSALQGLSQAMKLPSPSHHLWSLLCDATGRIFDLLPNRIRRNDLELYISIAKCLSEMTDEGVNQVSQITKDNIEKAAFVKLYLVSQGRLPLMSLTDLLTAAMQHPEKETLAWMILHSLYQARIVNHANTGVLKRLEWLLELMGYVRNIAYQSAPIQNVAPEEALDFLMLIFAAAVVAWADHEAPLLLGLSASWLPWHQQNGPGGPAAALLGRSPMHRVTVQEVLTQLPRSMLLLLQKEPWKEQTQKFIDWLLSIMEIPNKAFAAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW
uniprot
proteins
function
FUNCTION: Required for the maintenance of SKIC2 and SKIC3 proteostatic levels in the liver. May be involved in the regulation of RNA degradation by the exosome complex (By similarity). Potential tumor suppressor in gliomas. {ECO:0000250|UniProtKB:Q5VW36, ECO:0000269|PubMed:22427331}.
uniprot
proteins
mass_dalton
198950
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22427331
uniprot
proteins
sequence_length
1798
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q5VW36}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q5VW36}. Note=In astrocytes, colocalizes with VCL to the end of actin stress fibers, which normally terminate at focal adhesions. In hepatocytes, it is found in the cytosol. {ECO:0000250|UniProtKB:Q5VW36}.
uniprot
proteins