Tas2r4
entrez
554302
canonical
uniprot
Q67ET0
canonical
ensembl
ENSRNOG00000012195
resolver
ensembl
ENSRNOG00055032300
resolver
ensembl
ENSRNOG00060010825
resolver
ensembl
ENSRNOG00065018298
resolver
ensp
ENSRNOP00000016232
resolver
ensp
ENSRNOP00055045944
resolver
ensp
ENSRNOP00060014281
resolver
ensp
ENSRNOP00065024398
resolver
enst
ENSRNOT00000016232
resolver
enst
ENSRNOT00055055761
resolver
enst
ENSRNOT00060018322
resolver
enst
ENSRNOT00065030662
resolver
genesymbol
Tas2r4
resolver
genesymbol_syn
T2r16
resolver
genesymbol_syn
T2r20
resolver
genesymbol_syn
Tas2r108
resolver
uniprot_entry
TA2R4_RAT
resolver
amino_acid_sequence
MLWELYAFVFAASVVFNFVGIVANLFIIVIISKTWVKSHKISSSDKILFSLAITRFLTLGLFLLNTVYIATNTGRSVYFSTFFLLCWKFLDSNSLWLVTFLNCLYCVKITHFQHPVFLLLKRTVSMKTTSLLLACLLISAFTTLLYFVLTQISRFPEHIIGRNDTLFDVSDGILTLAASLILSSLLQFLLNVTFASLLIHSLRRHVQKMQRNRSSFWNPQTEAHVGAMRLMICFLVLYIPYSIAALLYFPSYMRKNLRAQAACMIITAAYPPGHSILLIITHHKLKAKAKKICCFYKLRDFVSN
uniprot
proteins
function
FUNCTION: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity). In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
34811
uniprot
proteins
protein_family
G protein-coupled receptor T2R family
uniprot
proteins
pubmed
15886333
uniprot
proteins
sequence_length
304
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 47..67; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 81..101; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 129..149; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 172..192; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 230..250; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins