Mctp1
entrez
309928
canonical
uniprot
D4ABL6
canonical
ensembl
ENSRNOG00000013282
resolver
ensembl
ENSRNOG00055022999
resolver
ensembl
ENSRNOG00060002708
resolver
ensembl
ENSRNOG00065005627
resolver
ensp
ENSRNOP00000017828
resolver
ensp
ENSRNOP00000058979
resolver
ensp
ENSRNOP00000076318
resolver
enst
ENSRNOT00000017828
resolver
genesymbol
Mctp1
resolver
uniprot
A0A1W2Q6L3
resolver
uniprot
A0A286YFH5
resolver
uniprot_entry
A0A286YFH5_RAT
resolver
uniprot_entry
MCTP1_RAT
resolver
uniprot_sec
A0A1W2Q6L3
resolver
amino_acid_sequence
MEPRGAAAGEPEPAVSPSFQARLWKNLQLGVGKGKGGGGGRAGGPERRTAATPTPSLPPPKTTQDVGSTGSRWSGFKKRKQVLDRVFSSSQPNLCCSSPEPLEPGGAGRAEQGSTLRRRLREHLLPVAKGSSTAAGTVGVTPPGGRSPDSAPSSSASSSLSSSPQPPPRGDRIRDEGTRRGSPEAHLCHQKSSSLPGTACLEQLLEPAPPPAEPARRPAEPQSLQKGEELDCSQKINPVETSNADVPLADPGMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGRKEVFRSKIIHKNLNPVWEEKACVLIDHLREPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNRPTDVTLTLKDPHYPDHDLGIILLSVILTPKEGEPRDVTMLMRKSWKRSSKFQTQSLRLSDQHRKSHLWRGIVSITLIEGRDLKAMDSNGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYEERGGVMDITAWDKDAGKRDDFIGRCQVDLSSLSREQTHKLELQLEEGEGHLVLLVTLTASATVSISDLSVNSMEDHKEREEILKRYSPLRIFNNIKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIKDIHSVLEVTVYDEDRDRSADFLGRVAIPLLSIQNGEQKAYVLKNKQLTGPTKGVIHLEIDVIFNAVKASLRTLIPKERKYIEEENRLSKQLLLRNFIRTKRCVMVLVNAAYYVNSCFDWDSPPRSLAAFVLFLLVVWNFELYMIPLLLLLLLTWNYFLIISGKDNRQRDTVVEDMLEDEEEEDDRDDKDGEKKGFINKIYAIQEVCVSVQNILDEAASLGERVKNTFNWTVPFLSWLAIIALCVFTAILYFIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFLSRVPSDVQVVQYQELKPDHSHSPYKRKKNNLG
uniprot
proteins
function
FUNCTION: Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity (By similarity). Overexpression in cultured neurons significantly inhibits neuronal transferrin endocytosis, secretory vesicle retrieval, cell migration, and oxidative stress from glutamate toxicity (PubMed:26195140). {ECO:0000250|UniProtKB:A1ZBD6, ECO:0000269|PubMed:26195140}.
uniprot
proteins
mass_dalton
106483
uniprot
proteins
protein_family
MCTP family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
26195140
uniprot
proteins
sequence_length
946
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:26195140}; Multi-pass membrane protein {ECO:0000255}. Recycling endosome {ECO:0000269|PubMed:26195140}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A1ZBD6}.
uniprot
proteins
transmembrane_region
TRANSMEM 758..778; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 861..881; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins