Tktl2
entrez
74419
canonical
uniprot
Q9D4D4
canonical
ensembl
ENSMUSG00000025519
resolver
ensp
ENSMUSP00000002025
resolver
ensp
ENSMUSP00000138388
resolver
enst
ENSMUST00000002025
resolver
enst
ENSMUST00000183187
resolver
genesymbol
Tktl2
resolver
uniprot
A0A0R4J2A3
resolver
uniprot
A2RSH3
resolver
uniprot_entry
A0A0R4J2A3_MOUSE
resolver
uniprot_entry
TKTL2_MOUSE
resolver
uniprot_sec
A2RSH3
resolver
amino_acid_sequence
MALARDAKLESDTLQVLQDVANRLRIHSIRATCACSSGHPTSCCSVAEIMAVLFFHTMRYKQADPEHPDNDRFVLSKGHAAPILYAVWVEVGRICESDLLNLRKIHCDLEGHPTPRLSFVDVATGSLGQGLGAACGMAYTGKYFDKASYRVFCLMGDGESSEGSVWEALAFASHYNLDNLVAIFDVNRLGQSGTAPLEHCTAVYEKRCQAFGWNTYVVDGHDVEALCQAFWKAAQVKNKPTALIAKTFKGRGIPNVEDAENWHGKPMPKDRADGIVKLIENRIQTNRNLTPKPPIEDSPRISMSNTKMTSLPVYKLGDMIATREAYGLALAKLGQSNQRVIVLDGDTKNSTFSEVFKKEHPERFIECFIAEQNMVSVALGCATRGRTIAFVSTFAAFLTRAFDQIRMGAISQTNINFVGSHCGVSVGEDGPSQMALEDLAMFRSIPNCTVFYPSDAVSTEHAVYLAANTKGMCFIRTTRPKTAVIYTAEENFVIGQAKVIRQSAVDKVTVIGAGVTLHEALVAAEELSQQGIFIRVIDLFTIKPLDAVTIIQSAKATGGQIITVEDHYREGGIGEAVCAAISREPDIVVRQLAVTEVPRSGKPSELLDMFGISARHIIAAVKDTVMK
uniprot
proteins
ec_number
2.2.1.1
uniprot
proteins
function
FUNCTION: Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (By similarity). {ECO:0000250|UniProtKB:Q9H0I9}.
uniprot
proteins
mass_dalton
68447
uniprot
proteins
protein_family
Transketolase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
627
uniprot
proteins