Snrnp70
entrez
20637
canonical
uniprot
Q62376
canonical
ensembl
ENSMUSG00000063511
resolver
ensp
ENSMUSP00000074160
resolver
ensp
ENSMUSP00000172750
resolver
ensp
ENSMUSP00000172753
resolver
ensp
ENSMUSP00000172754
resolver
genesymbol
Snrnp70
resolver
genesymbol_syn
Snrp70
resolver
uniprot
A2RS68
resolver
uniprot
Q3UIW4
resolver
uniprot
Q6ZWP0
resolver
uniprot_entry
A2RS68_MOUSE
resolver
uniprot_entry
Q6ZWP0_MOUSE
resolver
uniprot_entry
RU17_MOUSE
resolver
uniprot_sec
Q3UIW4
resolver
amino_acid_sequence
MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGGGGGGSGGGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDREHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE
uniprot
proteins
function
FUNCTION: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. {ECO:0000250|UniProtKB:P08621}.; FUNCTION: [Isoform 2]: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. {ECO:0000250|UniProtKB:P08621}.
uniprot
proteins
mass_dalton
51992
uniprot
proteins
post_translational_modification
PTM: Extensively phosphorylated on serine residues in the C-terminal region. {ECO:0000250|UniProtKB:P08621}.
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
17656373
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2525092
uniprot
proteins
sequence_length
448
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000269|PubMed:17656373}. Nucleus, nucleoplasm {ECO:0000269|PubMed:17656373}. Note=Colocalizes with SCNM1 and LUC7L2 in nuclear speckles. {ECO:0000269|PubMed:17656373}.
uniprot
proteins