OR1D2
entrez
4991
canonical
uniprot
P34982
canonical
ensembl
ENSG00000184166
resolver
ensp
ENSP00000493077
resolver
ensp
ENSP00000493103
resolver
enst
ENST00000641064
resolver
enst
ENST00000641833
resolver
genesymbol
OR1D2
resolver
genesymbol_syn
OLFR1
resolver
hgnc
HGNC:8183
resolver
uniprot
Q6IFL8
resolver
uniprot
Q96RA4
resolver
uniprot
Q9UM78
resolver
uniprot_entry
OR1D2_HUMAN
resolver
uniprot_sec
Q6IFL8
resolver
uniprot_sec
Q96RA4
resolver
uniprot_sec
Q9UM78
resolver
amino_acid_sequence
MDGGNQSEGSEFLLLGMSESPEQQRILFWMFLSMYLVTVVGNVLIILAISSDSRLHTPVYFFLANLSFTDLFFVTNTIPKMLVNLQSHNKAISYAGCLTQLYFLVSLVALDNLILAVMAYDRYVAICCPLHYTTAMSPKLCILLLSLCWVLSVLYGLIHTLLMTRVTFCGSRKIHYIFCEMYVLLRMACSNIQINHTVLIATGCFIFLIPFGFVIISYVLIIRAILRIPSVSKKYKAFSTCASHLGAVSLFYGTLCMVYLKPLHTYSVKDSVATVMYAVVTPMMNPFIYSLRNKDMHGALGRLLDKHFKRLT
uniprot
proteins
function
FUNCTION: Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception. {ECO:0000269|PubMed:12663925, ECO:0000269|PubMed:15458659, ECO:0000269|PubMed:16820410}.
uniprot
proteins
mass_dalton
35240
uniprot
proteins
mutagenesis
MUTAGEN 230; /note="S->A: Abolishes nuclear translocation of ARRB2; when associated with A-232 and A-239."; /evidence="ECO:0000269|PubMed:16820410"; MUTAGEN 232; /note="S->A: Abolishes nuclear translocation of ARRB2; when associated with A-230 and A-239."; /evidence="ECO:0000269|PubMed:16820410"; MUTAGEN 239; /note="S->A: Abolishes nuclear translocation of ARRB2; when associated with A-230 and A-232."; /evidence="ECO:0000269|PubMed:16820410"; MUTAGEN 312; /note="T->A: Abolishes nuclear translocation of ARRB2."; /evidence="ECO:0000269|PubMed:16820410
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10673334
uniprot
proteins
pubmed
12213199
uniprot
proteins
pubmed
12663925
uniprot
proteins
pubmed
14983052
uniprot
proteins
pubmed
15458659
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16820410
uniprot
proteins
pubmed
8004088
uniprot
proteins
pubmed
8097991
uniprot
proteins
sequence_length
312
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16820410}; Multi-pass membrane protein {ECO:0000269|PubMed:16820410}. Note=In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal.
uniprot
proteins
transmembrane_region
TRANSMEM 26..49; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 58..79; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 101..120; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 140..158; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 197..219; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 237..259; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 272..291; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins