Pycr3
entrez
66194
canonical
uniprot
Q9DCC4
canonical
ensembl
ENSMUSG00000022571
resolver
ensp
ENSMUSP00000049605
resolver
enst
ENSMUST00000053918
resolver
genesymbol
Pycr3
resolver
genesymbol_syn
Pycrl
resolver
uniprot
Q8R0P9
resolver
uniprot
Q9D0X2
resolver
uniprot_entry
P5CR3_MOUSE
resolver
uniprot_sec
Q8R0P9
resolver
uniprot_sec
Q9D0X2
resolver
amino_acid_sequence
MAATMSEPRRVGFVGAGRMAEAIARGLIQAGKVEAKQVLASAPTDNNLCHFRALGCQTTHSNHEVLQNCPLVIFATKPQVLPTVLAEVAPIVTTEHIIVSVAAGISLSTMEGLLPPNTRVLRVSPNLPCVVQEGAMVMARGHHAGNDDAELLQNLLEACGQCIEVPESYVDIHTGLSGSGVAFVCTFSEALAEGAIKMGMPSGLAHRIAAQTLLGTAKMLQQEGKHPAQLRTDVLTPAGTTIHGLHALERGGFRAATMSAVEAATCRAKELSKK
uniprot
proteins
ec_number
1.5.1.2
uniprot
proteins
function
FUNCTION: Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate (P5C) to L-proline using NAD(P)H. Proline is synthesized from either glutamate or ornithine; both are converted to P5C, and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCR3 is exclusively linked to the biosynthesis of proline from ornithine. {ECO:0000250|UniProtKB:Q53H96}.
uniprot
proteins
mass_dalton
28721
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. {ECO:0000250|UniProtKB:Q53H96}.
uniprot
proteins
protein_family
Pyrroline-5-carboxylate reductase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
274
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q53H96}.
uniprot
proteins