Icmt
entrez
170818
canonical
uniprot
Q9WVM4
canonical
ensembl
ENSRNOG00055015966
resolver
ensembl
ENSRNOG00060003637
resolver
ensembl
ENSRNOG00065009955
resolver
ensp
ENSRNOP00055021880
resolver
ensp
ENSRNOP00060004406
resolver
ensp
ENSRNOP00065012095
resolver
enst
ENSRNOT00055027142
resolver
enst
ENSRNOT00060005985
resolver
enst
ENSRNOT00065015996
resolver
genesymbol
Icmt
resolver
uniprot
G3V7G5
resolver
uniprot_entry
ICMT_RAT
resolver
uniprot_sec
G3V7G5
resolver
amino_acid_sequence
MAGCAARVPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSAAGLLMVIFGECLRKVAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVGL
uniprot
proteins
ec_number
2.1.1.100
uniprot
proteins
function
FUNCTION: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. {ECO:0000250|UniProtKB:O60725}.
uniprot
proteins
mass_dalton
31812
uniprot
proteins
protein_family
Class VI-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
Isoprenylcysteine carboxyl methyltransferase family
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
284
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O60725}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O60725}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..33; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 42..59; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 70..87; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 93..112; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 132..149; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 155..174; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 213..228; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 230..244; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins