Gpr19
entrez
312787
canonical
uniprot
P70585
canonical
ensembl
ENSRNOG00000007126
resolver
ensembl
ENSRNOG00055024911
resolver
ensembl
ENSRNOG00060015950
resolver
ensembl
ENSRNOG00065012005
resolver
ensp
ENSRNOP00000085068
resolver
ensp
ENSRNOP00000093658
resolver
ensp
ENSRNOP00000104788
resolver
ensp
ENSRNOP00000107664
resolver
ensp
ENSRNOP00000112467
resolver
ensp
ENSRNOP00055035045
resolver
ensp
ENSRNOP00055035072
resolver
ensp
ENSRNOP00060021906
resolver
ensp
ENSRNOP00060021930
resolver
ensp
ENSRNOP00065014944
resolver
ensp
ENSRNOP00065014954
resolver
enst
ENSRNOT00000116148
resolver
enst
ENSRNOT00000121405
resolver
enst
ENSRNOT00000131765
resolver
enst
ENSRNOT00000172279
resolver
enst
ENSRNOT00055042924
resolver
enst
ENSRNOT00055042966
resolver
enst
ENSRNOT00060027307
resolver
enst
ENSRNOT00060027337
resolver
enst
ENSRNOT00065019508
resolver
enst
ENSRNOT00065019518
resolver
genesymbol
Gpr19
resolver
uniprot
Q5FVI1
resolver
uniprot_entry
GPR19_RAT
resolver
uniprot_sec
Q5FVI1
resolver
amino_acid_sequence
MGFDHRMETDQPPVVTATLLVPLQNGSCVEAAEALLPHGLMELHEEHSWMSNRTDLQYELNPGEVATASIFFGALWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVVLQFTTGRWTLGSAMCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKRMIAASWILDAAFVTPVFFFYGSNWDSHCNYFLPPSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTLRRTMNIVPRTKVKTVKMFLLLNLVFLFSWLPFHVAQLWHPHEQDYRKSSLVFTAVTWVSFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKRNYVGISEIPPVSRTITKDSIYDSFDREAREKKLAWPINSNPPNTFV
uniprot
proteins
function
FUNCTION: G protein-coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism (PubMed:26739651). Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain (By similarity). May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence (By similarity). Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity (PubMed:29909017). {ECO:0000250|UniProtKB:Q15760, ECO:0000250|UniProtKB:Q61121, ECO:0000269|PubMed:26739651, ECO:0000269|PubMed:29909017}.
uniprot
proteins
mass_dalton
47634
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
26739651
uniprot
proteins
pubmed
29909017
uniprot
proteins
pubmed
8830667
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 70..90; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 103..123; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 153..173; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 183..203; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 222..242; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 278..298; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 310..332; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins