METAP1D
entrez
254042
canonical
uniprot
Q6UB28
canonical
ensembl
ENSG00000172878
resolver
ensembl
ENSG00000292097
resolver
ensp
ENSP00000315152
resolver
ensp
ENSP00000517833
resolver
enst
ENST00000315796
resolver
enst
ENST00000709703
resolver
genesymbol
METAP1D
resolver
genesymbol_syn
MAP1D
resolver
hgnc
HGNC:32583
resolver
uniprot
Q1WNX3
resolver
uniprot_entry
MAP12_HUMAN
resolver
uniprot_sec
Q1WNX3
resolver
amino_acid_sequence
MAAPSGVHLLVRRGSHRIFSSPLNHIYLHKQSSSQQRRNFFFRRQRDISHSIVLPAAVSSAHPVPKHIKKPDYVTTGIVPDWGDSIEVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMTTEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDEAIAACRAGAPFSVIGNTISHITHQNGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDLPMEEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEHTVLITSRGAQILTKLPHEA
uniprot
proteins
ec_number
3.4.11.18
uniprot
proteins
function
FUNCTION: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity). May play a role in colon tumorigenesis. {ECO:0000255|HAMAP-Rule:MF_03174, ECO:0000269|PubMed:16568094}.
uniprot
proteins
mass_dalton
37088
uniprot
proteins
protein_family
Methionine aminopeptidase type 1 subfamily
uniprot
proteins
protein_family
Peptidase M24A family
uniprot
proteins
pubmed
14532271
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16568094
uniprot
proteins
pubmed
17929833
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03174, ECO:0000269|PubMed:14532271}.
uniprot
proteins