Gins4
entrez
109145
canonical
uniprot
Q99LZ3
canonical
ensembl
ENSMUSG00000031546
resolver
ensp
ENSMUSP00000033950
resolver
enst
ENSMUST00000033950
resolver
genesymbol
Gins4
resolver
genesymbol_syn
Sld5
resolver
uniprot
Q3TP06
resolver
uniprot_entry
SLD5_MOUSE
resolver
uniprot_sec
Q3TP06
resolver
amino_acid_sequence
MTEVLDLHGQDSDGGSEEMVLTPAELIEKLEQAWMNEKFAPELLESKAEIVECVMEQLEHMEENLRRAKKGDLKVSIHRMEMERIRYVLSSYLRCRLMKIEKFFPHILEKEKVRSEGEPSSLSPEEFVFAKEYMDHTETHFKNVALKHMPPNLQKVDLLRAVPKPDLDSYVFLRVKERQENILVEPEADEQRDYVIDLEVGSQHLIRYKTIAPLVASGAVQLI
uniprot
proteins
function
FUNCTION: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. {ECO:0000250|UniProtKB:O75419}.
uniprot
proteins
mass_dalton
25961
uniprot
proteins
protein_family
GINS4/SLD5 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16338220
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
223
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16338220}. Chromosome {ECO:0000250|UniProtKB:Q7ZT48}. Cytoplasm {ECO:0000269|PubMed:16338220}.
uniprot
proteins