Tbc1d2
entrez
381605
canonical
uniprot
B1AVH7
canonical
ensembl
ENSMUSG00000039813
resolver
ensp
ENSMUSP00000081670
resolver
ensp
ENSMUSP00000208464
resolver
ensp
ENSMUSP00000208470
resolver
genesymbol
Tbc1d2
resolver
genesymbol_syn
Tbc1d2a
resolver
uniprot
Q3UFW9
resolver
uniprot
Q8BYB1
resolver
uniprot_entry
TBD2A_MOUSE
resolver
uniprot_sec
Q3UFW9
resolver
uniprot_sec
Q8BYB1
resolver
amino_acid_sequence
MEDAPERTPSSSESTQPPGLAREPEVVSPGDSEGCARPLDTVPKKLCGYLSKFGGKGPIKGWKCRWFFYDERKCHLYYSRTAQDANPLDSIDLSSAVFDCKADAEEEGTFEIKTPSRVITLKAATKQAMLYWLQQLQMKRWEFHNSPPALPATPAAALAENGPTLHLKLEQEEAELEEFLCPVKTPTGLVGAAAALQPVPAVPSALQNISLKHLGTEIQNTMHNIRGNKQAQAAAHGPLVEDSPQGGEPQSGEQPSISDPSLPEKEPEDPAKSAPRSSVPSGPTQKPKRQSNTFPFFSDGLARSRTAQEKVAALEQQVLMLTKELKSQKELVIILHKALEAAQQEKRASSAYLAATEDRDRLELVRHKVRQIAELNQRVEALEQGRERLAHEAGLREQQVQALQQHVQLLMDKNHAKQQVICKLTQKLTEDLAQPADATNGDFLSQQERMEHLKDDMEAYRTQNRFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEAAGAEAGDFPELLQQLIQEALQWEAGEADSVGLSPVSEYDDYGFLTVPDYEMEDLKLLAKIQALEVRSHHLLAHEAVERPLRDRWATLTELTPSAELKQLLRAGVPREHRPRVWRWLVHRRVRHLQAPGCYQELLARGRACEHPAARQIELDLNRTFPTNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEDEESAFWCLVAIVETILPAEYYSKTLTASQVDQRVLQDLLSEKLPRLTAHLGQHRVDLSLITFNWFLVVFADSLISDILLRVWDAFLYEGTKVVFRYALAIFKYNEEAILQLQDSLEIYQYLRFFTKTICDSRKLMSIAFNDMNPFPMKQLRQLRAAHRERLEAELRELELLKVEYLQRRASLGRAPPEGCVSEDEGEGDS
uniprot
proteins
function
FUNCTION: Acts as a GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
104260
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
922
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction {ECO:0000250}.
uniprot
proteins