Memo1
entrez
76890
canonical
uniprot
Q91VH6
canonical
ensembl
ENSMUSG00000058704
resolver
ensp
ENSMUSP00000156437
resolver
ensp
ENSMUSP00000156607
resolver
ensp
ENSMUSP00000225302
resolver
enst
ENSMUST00000232989
resolver
enst
ENSMUST00000233514
resolver
genesymbol
Memo1
resolver
uniprot
A0A3B2W7C9
resolver
uniprot_entry
A0A3B2W7C9_MOUSE
resolver
uniprot_entry
MEMO1_MOUSE
resolver
amino_acid_sequence
MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYTYCGSCAAHAYKQVDPSVTRRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLLNAITELQKNGMNMSFSFLNYAQSSQCRSWQDSSVSYAAGALTVH
uniprot
proteins
function
FUNCTION: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33692
uniprot
proteins
protein_family
MEMO1 family
uniprot
proteins
pubmed
11707072
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17947660
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
297
uniprot
proteins