Npr2
entrez
230103
canonical
uniprot
Q6VVW5
canonical
ensembl
ENSMUSG00000028469
resolver
ensp
ENSMUSP00000030191
resolver
ensp
ENSMUSP00000114385
resolver
ensp
ENSMUSP00000320593
resolver
genesymbol
Npr2
resolver
uniprot
B1AWI8
resolver
uniprot
Q6VVW3
resolver
uniprot
Q6VVW4
resolver
uniprot
Q8CGA9
resolver
uniprot_entry
ANPRB_MOUSE
resolver
uniprot_sec
B1AWI8
resolver
uniprot_sec
Q6VVW3
resolver
uniprot_sec
Q6VVW4
resolver
uniprot_sec
Q8CGA9
resolver
amino_acid_sequence
MALPSLLLVVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRALPVDLRFVSSELDGACSEYLAPLRAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGFAAKNEHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTQEQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELAPSLMNLIAGCFYDGILLYAQVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPLDNPPCAFDLDDPSCDKTPLSTLAIVALGTGVTFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNSDRYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFAIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGEQKGPPGLL
uniprot
proteins
ec_number
4.6.1.2
uniprot
proteins
function
FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. {ECO:0000269|PubMed:15572448}.
uniprot
proteins
mass_dalton
117060
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. {ECO:0000250|UniProtKB:P16067}.; PTM: Glycosylated. {ECO:0000250|UniProtKB:P20594}.
uniprot
proteins
protein_family
Adenylyl cyclase class-4/guanylyl cyclase family
uniprot
proteins
pubmed
14514678
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15572448
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1047
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P20594}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P20594}.
uniprot
proteins
transmembrane_region
TRANSMEM 459..478; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins