Cyp4x1
entrez
246767
canonical
uniprot
Q8K4D6
canonical
ensembl
ENSRNOG00000043513
resolver
ensembl
ENSRNOG00055031360
resolver
ensembl
ENSRNOG00060029479
resolver
ensembl
ENSRNOG00065015575
resolver
ensp
ENSRNOP00000011985
resolver
ensp
ENSRNOP00055044901
resolver
ensp
ENSRNOP00060042568
resolver
ensp
ENSRNOP00065020351
resolver
enst
ENSRNOT00000011985
resolver
enst
ENSRNOT00055054312
resolver
enst
ENSRNOT00060051160
resolver
enst
ENSRNOT00065025865
resolver
genesymbol
Cyp4x1
resolver
uniprot_entry
CP4X1_RAT
resolver
amino_acid_sequence
MEASWLENRWARPLHLALVFCLALVLMQAVKLYLRRQRLLRDLRPFPGPTAHWLLGHQKFLQEDNMEKLDEIVKEYPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKTQYLHQLMTPFLGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTEKIIQDRKKTLKDQVNQDDTQTSQNFLDIVLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGSSITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLRPKHGIYLHLKKLPEC
uniprot
proteins
ec_number
1.14.14.-
uniprot
proteins
function
FUNCTION: A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling. Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). {ECO:0000250|UniProtKB:Q8N118}.
uniprot
proteins
mass_dalton
58574
uniprot
proteins
protein_family
Cytochrome P450 family
uniprot
proteins
pubmed
12176035
uniprot
proteins
sequence_length
507
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q6A152}; Single-pass membrane protein {ECO:0000255}. Microsome membrane {ECO:0000250|UniProtKB:Q6A152}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 14..34; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins