CKLF
entrez
51192
canonical
uniprot
Q9UBR5
canonical
ensembl
ENSG00000217555
resolver
ensp
ENSP00000264001
resolver
ensp
ENSP00000264003
resolver
ensp
ENSP00000290771
resolver
ensp
ENSP00000355417
resolver
ensp
ENSP00000416678
resolver
genesymbol
CKLF
resolver
genesymbol_syn
CKLF1
resolver
hgnc
HGNC:13253
resolver
uniprot
C9JE38
resolver
uniprot
Q5BJH6
resolver
uniprot
Q9UHM7
resolver
uniprot
Q9UHN8
resolver
uniprot
Q9UI41
resolver
uniprot_entry
CKLF_HUMAN
resolver
uniprot_entry
Q5BJH6_HUMAN
resolver
uniprot_sec
C9JE38
resolver
uniprot_sec
Q9UHM7
resolver
uniprot_sec
Q9UHN8
resolver
uniprot_sec
Q9UI41
resolver
activity_regulation
ACTIVITY REGULATION: Partly inhibited by interleukin 10. {ECO:0000269|PubMed:11415443}.
uniprot
proteins
amino_acid_sequence
MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL
uniprot
proteins
function
FUNCTION: May play an important role in inflammation and regeneration of skeletal muscle (PubMed:11415443). Essential for embryonic development (By similarity). {ECO:0000250|UniProtKB:Q9DAS1, ECO:0000269|PubMed:11415443}.; FUNCTION: [Isoform 1]: Has chemotactic response in monocytes, neutrophils and lymphocytes (PubMed:11415443). Binds CCR4 (PubMed:16137713). {ECO:0000269|PubMed:11415443, ECO:0000269|PubMed:16137713}.
uniprot
proteins
mass_dalton
17170
uniprot
proteins
protein_family
Chemokine-like factor family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
11415443
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
16137713
uniprot
proteins
sequence_length
152
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Secreted {ECO:0000269|PubMed:11415443, ECO:0000269|PubMed:16137713}.; SUBCELLULAR LOCATION: [Isoform 2]: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 4]: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 81..101; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 108..128; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins