PDP2
entrez
57546
canonical
uniprot
Q9P2J9
canonical
ensembl
ENSG00000172840
resolver
ensp
ENSP00000309548
resolver
ensp
ENSP00000523944
resolver
ensp
ENSP00000523945
resolver
ensp
ENSP00000523946
resolver
ensp
ENSP00000596870
resolver
ensp
ENSP00000596871
resolver
ensp
ENSP00000596872
resolver
ensp
ENSP00000596873
resolver
ensp
ENSP00000596874
resolver
ensp
ENSP00000611623
resolver
ensp
ENSP00000611624
resolver
ensp
ENSP00000611625
resolver
ensp
ENSP00000611626
resolver
ensp
ENSP00000611627
resolver
enst
ENST00000311765
resolver
enst
ENST00000853885
resolver
enst
ENST00000853886
resolver
enst
ENST00000853887
resolver
enst
ENST00000926811
resolver
enst
ENST00000926812
resolver
enst
ENST00000926813
resolver
enst
ENST00000926814
resolver
enst
ENST00000926815
resolver
enst
ENST00000941564
resolver
enst
ENST00000941565
resolver
enst
ENST00000941566
resolver
enst
ENST00000941567
resolver
enst
ENST00000941568
resolver
genesymbol
PDP2
resolver
genesymbol_syn
KIAA1348
resolver
hgnc
HGNC:30263
resolver
uniprot
A8K924
resolver
uniprot_entry
PDP2_HUMAN
resolver
uniprot_sec
A8K924
resolver
amino_acid_sequence
MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
uniprot
proteins
ec_number
3.1.3.43
uniprot
proteins
function
FUNCTION: Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA (By similarity). Acts as a crucial regulator of T cell metabolism and function, with a particular focus on T-helper Th17 (By similarity). {ECO:0000250|UniProtKB:O88484, ECO:0000250|UniProtKB:Q504M2}.
uniprot
proteins
mass_dalton
59978
uniprot
proteins
protein_family
PP2C family
uniprot
proteins
pubmed
10718198
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
529
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:O88484}.
uniprot
proteins