SUMF2
entrez
25870
canonical
uniprot
Q8NBJ7
canonical
ensembl
ENSG00000129103
resolver
ensp
ENSP00000275607
resolver
ensp
ENSP00000341938
resolver
ensp
ENSP00000378824
resolver
ensp
ENSP00000400922
resolver
ensp
ENSP00000406445
resolver
ensp
ENSP00000498981
resolver
ensp
ENSP00000498997
resolver
ensp
ENSP00000669569
resolver
ensp
ENSP00000669571
resolver
ensp
ENSP00000669573
resolver
ensp
ENSP00000765555
resolver
enst
ENST00000395436
resolver
enst
ENST00000413756
resolver
genesymbol
SUMF2
resolver
hgnc
HGNC:20415
resolver
uniprot
A8MXB9
resolver
uniprot
B4DU41
resolver
uniprot
B4DWQ0
resolver
uniprot
C9J660
resolver
uniprot
Q14DW5
resolver
uniprot
Q53ZE3
resolver
uniprot
Q96BH2
resolver
uniprot
Q9BRN3
resolver
uniprot
Q9BWI1
resolver
uniprot
Q9Y405
resolver
uniprot_entry
A8MXB9_HUMAN
resolver
uniprot_entry
C9J660_HUMAN
resolver
uniprot_entry
SUMF2_HUMAN
resolver
uniprot_sec
B4DU41
resolver
uniprot_sec
B4DWQ0
resolver
uniprot_sec
Q14DW5
resolver
uniprot_sec
Q53ZE3
resolver
uniprot_sec
Q96BH2
resolver
uniprot_sec
Q9BRN3
resolver
uniprot_sec
Q9BWI1
resolver
uniprot_sec
Q9Y405
resolver
amino_acid_sequence
MARHGLPLLPLLSLLVGAWLKLGNGQATSMVQLQGGRFLMGTNSPDSRDGDGPVREATVKPFAIDIFPVTNKDFRDFVREKKYRTEAEMFGWSFVFEDFVSDELRNKATQPMKSVLWWLPVEKAFWRQPAGPGSGIRERLEHPVLHVSWNDARAYCAWRGKRLPTEEEWEFAARGGLKGQVYPWGNWFQPNRTNLWQGKFPKGDKAEDGFHGVSPVNAFPAQNNYGLYDLLGNVWEWTASPYQAAEQDMRVLRGASWIDTADGSANHRARVTTRMGNTPDSASDNLGFRCAADAGRPPGEL
uniprot
proteins
function
FUNCTION: Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. {ECO:0000269|PubMed:12757706, ECO:0000269|PubMed:15708861, ECO:0000269|PubMed:15962010}.
uniprot
proteins
mass_dalton
33843
uniprot
proteins
mutagenesis
MUTAGEN 156; /note="C->A: Abolishes interaction with and inhibition of SUMF1. Can still form homodimers."; /evidence="ECO:0000269|PubMed:15962010"; MUTAGEN 290; /note="C->A: Abolishes interaction with and inhibition of SUMF1. Can still form homodimers."; /evidence="ECO:0000269|PubMed:15962010"; MUTAGEN 298..301; /note="Missing: Abolishes endoplasmic reticulum retention."; /evidence="ECO:0000269|PubMed:18266766"; MUTAGEN 298..299; /note="PG->KD: Does not affect endoplasmic reticulum retention."; /evidence="ECO:0000269|PubMed:18266766"; MUTAGEN 298; /note="P->S: Does not affect endoplasmic reticulum retention."; /evidence="ECO:0000269|PubMed:18266766
uniprot
proteins
protein_family
Sulfatase-modifying factor family
uniprot
proteins
pubmed
12757706
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15687489
uniprot
proteins
pubmed
15708861
uniprot
proteins
pubmed
15962010
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18266766
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28397838
uniprot
proteins
sequence_length
301
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000269|PubMed:15708861, ECO:0000269|PubMed:15962010, ECO:0000269|PubMed:18266766}.
uniprot
proteins