Q9DBZ9
uniprot
Q9DBZ9
canonical
amino_acid_sequence
MAEPLLRKTFSRLRGREKLPRKKSEAKDRGHPAQRSEPKPPEPEPRVLEGSQAGAEVPPSPETPRSPTRGAYLQSLEPSSRRWVLGGAKPPEEISLGPRTPSSGEPAGEIWYNPIPEEDPRPPAPEPLGSQLASSEPEGPNIQGAAPTSPPTKTSRTKSPGPARRLSMKMKKLPELRRRLSLRSTRTGRDRERTAPAGSVISRYRLDSSVGTPGQASVAGGSRSPRGGYLSDGDSPERPGGPPSPTAFRPYEVGPSARTPPAALWGRLSLHLYGLGGLRPSPGATPRDLCCLLQVDGVARARTGPLRSGPDFLRLDHTFHLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTIFRGCQAQQLAVRLEPQGFLYAKLTLSEQQEAPATAEPRVFGLPLQLLVEREQSPGQVPLIIRKCVGQIECRGLRVVGLYRLCGSAAVKKELRDAFEQDSAAVCLSEDVYPDINVITGILKDYLRELPTPLITQPLYQVVLEAMAQGHPSRASLGPEGTRGLLRCLPDVERATLTLLLDHLRLVSSFHTHNRMTPQNXAVCFGPVLLPARQTPSRPRLRSSGPGVTSAVDFKRHIEVLHYLLQSWPDTRRPSDTPDGAVAPYLRPKRQPPLHLPLAGPEVVTRPRGRGGPESPPSNRYAGDWSVCGGDLLPCGRDFLSGPDYDHVTGSDSEEDDDETGEPRGTTDFEDEFDAPFNPHLNLKDFDALILDLERELSKQINVCL
uniprot
proteins
function
FUNCTION: GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1. {ECO:0000250|UniProtKB:Q6ZW31}.
uniprot
proteins
mass_dalton
80496
uniprot
proteins
post_translational_modification
PTM: Palmitoylated. Probably palmitoylated by ZDHHC3 and ZDHHC7. {ECO:0000250|UniProtKB:D3ZZN9}.
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27917469
uniprot
proteins
sequence_length
737
uniprot
proteins