GRIK4
entrez
2900
canonical
uniprot
Q16099
canonical
ensembl
ENSG00000149403
resolver
ensp
ENSP00000404063
resolver
ensp
ENSP00000435648
resolver
ensp
ENSP00000492086
resolver
ensp
ENSP00000573084
resolver
ensp
ENSP00000573087
resolver
ensp
ENSP00000573091
resolver
ensp
ENSP00000573093
resolver
ensp
ENSP00000640174
resolver
enst
ENST00000438375
resolver
enst
ENST00000527524
resolver
enst
ENST00000638419
resolver
enst
ENST00000903025
resolver
genesymbol
GRIK4
resolver
genesymbol_syn
GRIK
resolver
hgnc
HGNC:4582
resolver
uniprot
A0A8D9PH79
resolver
uniprot
A0A8D9UJ88
resolver
uniprot
A6H8K8
resolver
uniprot
A8K9L1
resolver
uniprot
B2RAP6
resolver
uniprot_entry
A0A8D9PH79_HUMAN
resolver
uniprot_entry
A0A8D9UJ88_HUMAN
resolver
uniprot_entry
A6H8K8_HUMAN
resolver
uniprot_entry
B2RAP6_HUMAN
resolver
uniprot_entry
GRIK4_HUMAN
resolver
uniprot_sec
A8K9L1
resolver
amino_acid_sequence
MPRVSAPLVLLPAWLVMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVKFQFQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSHLYASNISDTLFNTTLVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEATEVSVCQEMVTELRSIILCQDSIHPRRRRAAVPPPRPPIPEERRPRGTATLSNGKLCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWEKTTNSSEPE
uniprot
proteins
function
FUNCTION: Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel. Cannot form functional channels on its own (PubMed:8263508). Shows channel activity only in heteromeric assembly with GRIK1, GRIK2 and GRIK3 subunits (By similarity). {ECO:0000250|UniProtKB:Q01812, ECO:0000269|PubMed:8263508}.
uniprot
proteins
mass_dalton
107246
uniprot
proteins
protein_family
GRIK4 subfamily
uniprot
proteins
protein_family
Glutamate-gated ion channel (TC 1.A.10.1) family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
8263508
uniprot
proteins
sequence_length
956
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:8263508}; Multi-pass membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q8BMF5}; Multi-pass membrane protein {ECO:0000255}. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q8BMF5}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 546..566; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 624..644; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 805..825; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins