St3gal5
entrez
20454
canonical
uniprot
O88829
canonical
ensembl
ENSMUSG00000056091
resolver
ensp
ENSMUSP00000070414
resolver
ensp
ENSMUSP00000109747
resolver
ensp
ENSMUSP00000227390
resolver
enst
ENSMUST00000114112
resolver
genesymbol
St3gal5
resolver
genesymbol_syn
GM3S
resolver
genesymbol_syn
Siat9
resolver
uniprot
A0A0R4J1J3
resolver
uniprot
B2RRS1
resolver
uniprot
Q3TMT6
resolver
uniprot
Q3TY01
resolver
uniprot
Q91YF2
resolver
uniprot
Q91YF3
resolver
uniprot
Q9CZ65
resolver
uniprot
Q9QWF8
resolver
uniprot
Q9QWF9
resolver
uniprot_entry
A0A0R4J1J3_MOUSE
resolver
uniprot_entry
SIAT9_MOUSE
resolver
uniprot_sec
B2RRS1
resolver
uniprot_sec
Q3TMT6
resolver
uniprot_sec
Q3TY01
resolver
uniprot_sec
Q91YF2
resolver
uniprot_sec
Q91YF3
resolver
uniprot_sec
Q9CZ65
resolver
uniprot_sec
Q9QWF8
resolver
uniprot_sec
Q9QWF9
resolver
amino_acid_sequence
MHTEAVGGAARRPQKLRSQAAAPACRAMPSEFTSAKLRSDCSRTSLQWYTRTQHKMRRPSLLIKDICKCTLVAFGVWLLYILILNYTAEECDMKRMHYVDPDRIKRAQSYAQEVLQKECRPRYAKTAMALLFEDRYSINLEPFVQKVPTASEAELKYDPPFGFRKFSSKVQSLLDMLPEHDFPEHLRAKACKRCVVVGNGGILHGLELGHALNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPEGAPLSDVEYYANDLFVTVLFKSVDFKWLQAMVKNESLPFWVRLFFWKQVAEKVPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGHDKNIPTIGVIAVVLATHLCDEVSLAGFGYDLSQPRTPLHYFDSQCMGAMHWQVMHNVTTETKFLLKLLKEGVVEDLSGGIH
uniprot
proteins
ec_number
2.4.3.9
uniprot
proteins
function
FUNCTION: (Microbial infection) Gangliosides GD1b and GT1b (derived from GM3) may serve as receptors for some C.botulinum neurotoxins (minimally types BoNT/A, B, C) (PubMed:16115873). {ECO:0000305|PubMed:16115873}.; FUNCTION: Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis) (PubMed:10092602, PubMed:12629211, PubMed:9875239). Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D-galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer (LacCer) (By similarity). {ECO:0000250|UniProtKB:Q9UNP4, ECO:0000269|PubMed:10092602, ECO:0000269|PubMed:12629211, ECO:0000269|PubMed:9875239}.
uniprot
proteins
mass_dalton
47360
uniprot
proteins
protein_family
Glycosyltransferase 29 family
uniprot
proteins
pubmed
10092602
uniprot
proteins
pubmed
12629211
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16115873
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
9875239
uniprot
proteins
sequence_length
414
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 66..86; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins