Aadat
entrez
29416
canonical
uniprot
Q64602
canonical
ensembl
ENSRNOG00000011861
resolver
ensembl
ENSRNOG00055012248
resolver
ensembl
ENSRNOG00060006840
resolver
ensembl
ENSRNOG00065004394
resolver
ensp
ENSRNOP00000015974
resolver
ensp
ENSRNOP00000105590
resolver
ensp
ENSRNOP00000107369
resolver
ensp
ENSRNOP00055016815
resolver
ensp
ENSRNOP00060008370
resolver
ensp
ENSRNOP00065004513
resolver
enst
ENSRNOT00000015974
resolver
enst
ENSRNOT00000128898
resolver
enst
ENSRNOT00000133634
resolver
enst
ENSRNOT00055020837
resolver
enst
ENSRNOT00060011207
resolver
enst
ENSRNOT00065006411
resolver
genesymbol
Aadat
resolver
genesymbol_syn
Kat2
resolver
uniprot
A0ABK0L6P1
resolver
uniprot
A0ABK0LY24
resolver
uniprot_entry
A0ABK0L6P1_RAT
resolver
uniprot_entry
A0ABK0LY24_RAT
resolver
uniprot_entry
AADAT_RAT
resolver
amino_acid_sequence
MNYSRFLTATSLARKTSPIRATVEIMSRAPKDIISLAPGSPNPKVFPFKSAVFTVENGSTIRFEGEMFQRALQYSSSYGIPELLSWLKQLQIKLHNPPTVNYSPNEGQMDLCITSGCQDGLCKVFEMLINPGDTVLVNEPLYSGALFAMKPLGCNFISVPSDDCGIIPEGLKKVLSQWKPEDSKDPTKRTPKFLYTIPNGNNPTGNSLTGDRKKEIYELARKYDFLIIEDDPYYFLQFTKPWEPTFLSMDVDGRVIRADSLSKVISSGLRVGFITGPKSLIQRIVLHTQISSLHPCTLSQLMISELLYQWGEEGFLAHVDRAIDFYKNQRDFILAAADKWLRGLAEWHVPKAGMFLWIKVNGISDAKKLIEEKAIEREILLVPGNSFFVDNSAPSSFFRASFSQVTPAQMDLVFQRLAQLIKDVS
uniprot
proteins
ec_number
2.6.1.39
uniprot
proteins
ec_number
2.6.1.4
uniprot
proteins
ec_number
2.6.1.63
uniprot
proteins
ec_number
2.6.1.7
uniprot
proteins
ec_number
2.6.1.73
uniprot
proteins
function
FUNCTION: Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). {ECO:0000269|PubMed:7493966}.
uniprot
proteins
mass_dalton
47784
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 4/6.
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
Class-I pyridoxal-phosphate-dependent aminotransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
7493966
uniprot
proteins
sequence_length
425
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
uniprot
proteins