ATP5J
entrez
522
canonical
uniprot
P18859
canonical
ensembl
ENSG00000154723
resolver
ensp
ENSP00000284971
resolver
ensp
ENSP00000382959
resolver
ensp
ENSP00000382962
resolver
ensp
ENSP00000382965
resolver
ensp
ENSP00000382966
resolver
ensp
ENSP00000389649
resolver
ensp
ENSP00000594823
resolver
genesymbol
ATP5J
resolver
genesymbol
ATP5PF
resolver
genesymbol_syn
ATP5A
resolver
genesymbol_syn
ATP5J
resolver
genesymbol_syn
ATPM
resolver
hgnc
HGNC:847
resolver
uniprot
J3KQ83
resolver
uniprot
Q6IB54
resolver
uniprot
Q6NZ59
resolver
uniprot_entry
ATP5J_HUMAN
resolver
uniprot_entry
Q6IB54_HUMAN
resolver
uniprot_entry
Q6NZ59_HUMAN
resolver
uniprot_sec
J3KQ83
resolver
amino_acid_sequence
MILQRLFRFSSVIRSAVSVHLRRNIGVTAVAFNKELDPIQKLFVDKIREYKSKRQTSGGPVDASSEYQQELERELFKLKQMFGNADMNTFPTFKFEDPKFEVIEKPQA
uniprot
proteins
function
FUNCTION: Subunit F6, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (PubMed:37244256). Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity). {ECO:0000250|UniProtKB:P02721, ECO:0000250|UniProtKB:P19483, ECO:0000269|PubMed:37244256, ECO:0000305|PubMed:37244256}.
uniprot
proteins
mass_dalton
12588
uniprot
proteins
protein_family
Eukaryotic ATPase subunit F6 family
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
1286669
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17213182
uniprot
proteins
pubmed
1825642
uniprot
proteins
pubmed
1830479
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
29961568
uniprot
proteins
pubmed
37244256
uniprot
proteins
sequence_length
108
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion. Mitochondrion inner membrane.
uniprot
proteins