PTGR3
entrez
284273
canonical
uniprot
Q8N4Q0
canonical
ensembl
ENSG00000180011
resolver
ensp
ENSP00000323678
resolver
ensp
ENSP00000440111
resolver
genesymbol
PTGR3
resolver
genesymbol
ZADH2
resolver
genesymbol_syn
ZADH2
resolver
hgnc
HGNC:28697
resolver
uniprot
A8KA15
resolver
uniprot
B4DZ91
resolver
uniprot
Q4G1C4
resolver
uniprot_entry
PTGR3_HUMAN
resolver
uniprot_entry
Q4G1C4_HUMAN
resolver
uniprot_sec
A8KA15
resolver
uniprot_sec
B4DZ91
resolver
amino_acid_sequence
MLRLVPTGARAIVDMSYARHFLDFQGSAIPQAMQKLVVTRLSPNFREAVTLSRDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGSFAEYTVVPASIATPVPSVKPEYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESIFRAVNYMYMGKNTGKIVVELPHSVNSKL
uniprot
proteins
ec_number
1.3.1.48
uniprot
proteins
function
FUNCTION: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. {ECO:0000250|UniProtKB:Q8BGC4}.
uniprot
proteins
mass_dalton
40140
uniprot
proteins
protein_family
Quinone oxidoreductase subfamily
uniprot
proteins
protein_family
Zinc-containing alcohol dehydrogenase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16177791
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
377
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000250|UniProtKB:Q8BGC4}.
uniprot
proteins