Mthfd1l
entrez
270685
canonical
uniprot
Q3V3R1
canonical
ensembl
ENSMUSG00000040675
resolver
ensp
ENSMUSP00000036178
resolver
ensp
ENSMUSP00000112870
resolver
ensp
ENSMUSP00000112897
resolver
enst
ENSMUST00000043735
resolver
enst
ENSMUST00000117291
resolver
enst
ENSMUST00000120585
resolver
genesymbol
Mthfd1l
resolver
genesymbol_syn
Fthfsdc1
resolver
uniprot
Q3TVQ0
resolver
uniprot
Q3V402
resolver
uniprot
Q80V98
resolver
uniprot
Q8CAL0
resolver
uniprot
Q8K2N5
resolver
uniprot_entry
C1TM_MOUSE
resolver
uniprot_sec
Q3TVQ0
resolver
uniprot_sec
Q3V402
resolver
uniprot_sec
Q80V98
resolver
uniprot_sec
Q8CAL0
resolver
uniprot_sec
Q8K2N5
resolver
amino_acid_sequence
MSVRLPLLLRQLGRQQLPSGPACRLRELCRSGSRSSSSGGGDPEGLRGRRLQDGQTFSSHGPGNPEAPGMDSIVRDVIHNSKEVLSLLQEKNPAFKPVLVVIQAGDDNLMKDMNQNLAKEAGLDITHICLPPDSGEDEIIDEILKINEDPRVHGLTLQISEDSLSNKVLNALKPEKDVDGVTDINLGKLVRGDAPECFVSPLAKAAVELVEKSGITLDGKKVLVVGAHGPLEAALQWLFQRKGSMTMSCPWATPQLPDKLREADIVVLGSPKPEEIPAVWIPSGTTILNCFHDFLSGKLSGGSPGVPVDKLIAEESVSLLAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVPSDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVQLSLLERLKDQTDGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLKVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHESTQTDKALYNRLVPLVNGVREFSEIQLSRLKKLGIHKTDPSTLTEEEVRKFARLNIDPATITWQRVLDTNDRFLRKITIGQGSTEKGYSRQAQFDIAVASEIMAVLALTDSLTDMKERLGRMVVASDKDGQPVTAEDLGVTGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGADIGMEKFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEENIQLVADGCCNLQKQIQIAQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSAGGKGSVDLARAVREAANKRSRFQFLYDVQLPIVEKIRVIAQTVYGAKDIELSPEAQSKIDRYTQQGFGNLPICMAKTHLSLSHEPDKKGVPRDFTLPISDVRASIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDTETEQVKGLF
uniprot
proteins
ec_number
6.3.4.3
uniprot
proteins
function
FUNCTION: May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2. {ECO:0000269|PubMed:15611115}.
uniprot
proteins
mass_dalton
105729
uniprot
proteins
pathway_participation
PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion. {ECO:0000305|PubMed:15611115}.
uniprot
proteins
protein_family
Tetrahydrofolate dehydrogenase/cyclohydrolase family; Formate--tetrahydrofolate ligase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15611115
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
977
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305|PubMed:15611115}.
uniprot
proteins