Kif21a
entrez
16564
canonical
uniprot
Q9QXL2
canonical
ensembl
ENSMUSG00000022629
resolver
ensp
ENSMUSP00000066911
resolver
ensp
ENSMUSP00000085985
resolver
ensp
ENSMUSP00000104910
resolver
ensp
ENSMUSP00000104911
resolver
ensp
ENSMUSP00000271623
resolver
ensp
ENSMUSP00000271624
resolver
ensp
ENSMUSP00000271626
resolver
ensp
ENSMUSP00000271628
resolver
ensp
ENSMUSP00000271635
resolver
ensp
ENSMUSP00000271638
resolver
ensp
ENSMUSP00000271639
resolver
ensp
ENSMUSP00000271642
resolver
enst
ENSMUST00000067205
resolver
genesymbol
Kif21a
resolver
genesymbol_syn
Kiaa1708
resolver
uniprot
F8WGN6
resolver
uniprot
Q3TQJ5
resolver
uniprot
Q3UHE7
resolver
uniprot
Q3V416
resolver
uniprot
Q6P5H1
resolver
uniprot
Q6ZPJ8
resolver
uniprot
Q8BWZ9
resolver
uniprot
Q8BXF1
resolver
uniprot_entry
F8WGN6_MOUSE
resolver
uniprot_entry
KI21A_MOUSE
resolver
uniprot_entry
Q3TQJ5_MOUSE
resolver
uniprot_entry
Q3UHE7_MOUSE
resolver
uniprot_entry
Q3V416_MOUSE
resolver
uniprot_sec
Q6P5H1
resolver
uniprot_sec
Q6ZPJ8
resolver
uniprot_sec
Q8BWZ9
resolver
uniprot_sec
Q8BXF1
resolver
amino_acid_sequence
MLGAADESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIMEEEQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQTDAENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRARITQLVSEQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSASSAFSPTILSSDKETIEIIDLAKKDLEKLKRKEKKKKKRLQKLEESGREERSVAGKDDNADTDQEKKEEKGVSEKENNELDVEENQEVSDHEDEEEEEEDEEEEDDIEGEESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVKCEYEKKLHAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSESPAPDTGSSAASGEADTSRPGTQQKMRIPVARVQALPTPTTNGTRKKYQRKGFTGRVFTSKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLRQREELTKRREKLSKRREKIVKESGEGDKSVANIIEEMESLTANIDYINDSIADCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDGAPPENEEDSSEEDGPLHSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSEVASDTSAGDASLSGPLAPVAEGQEIGMNTETSGTSARDKELLAPSGLPSKIGSISRQSSLSEKKVPEPSPVTRRKAYEKADKPKAKEHKHSDSGASETSLSPPSSPPSRPRNELNVFNRLTVPQGTPSVQQDKSDESDSSLSEVHRGIINPFPACKGVRASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDSPINAICVNSTHVFTAADDRTVRIWKAHNLQDGQLSDTGDLGEDIASN
uniprot
proteins
function
FUNCTION: Processive microtubule plus-end directed motor protein involved in neuronal axon guidance. Is recruited by KANK1 to cortical microtubule stabilizing complexes (CMSCs) at focal adhesions (FAs) rims where it promotes microtubule capture and stability. Controls microtubule polymerization rate at axonal growth cones and suppresses microtubule growth without inducing microtubule disassembly once it reaches the cell cortex. {ECO:0000250|UniProtKB:Q7Z4S6, ECO:0000269|PubMed:10225949}.
uniprot
proteins
mass_dalton
186536
uniprot
proteins
mutagenesis
MUTAGEN 1156; /note="R->E: Abolishes binding to KANK1."; /evidence="ECO:0000269|PubMed:29217769"; MUTAGEN 1165; /note="L->Q: Decreases the binding affinity for KANK1 by 20-fold."; /evidence="ECO:0000269|PubMed:29217769
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
10225949
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
29217769
uniprot
proteins
sequence_length
1672
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10225949}. Cytoplasm, cell cortex {ECO:0000269|PubMed:21183079}. Cell projection, dendrite {ECO:0000269|PubMed:10225949}. Cell projection, axon {ECO:0000269|PubMed:10225949}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q7Z4S6}. Note=In neurons, localized to axons and dendrites. {ECO:0000269|PubMed:10225949}.
uniprot
proteins