P16453
uniprot
P16453
canonical
activity_regulation
ACTIVITY REGULATION: Phosphorylation of brain HDC by cAMP-dependent protein kinase leads to enzyme inactivation.
uniprot
proteins
amino_acid_sequence
MMEPSEYHEYQARGKEMVDYICQYLSTVRERQVTPNVKPGYLRAQIPSSAPEEPDSWDSIFGDIEQIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLGLPDFFLHHHPSSQGGGVLQRTVSESTLIALLAARKNKILEMKAHEPNADESSLNARLVAYASDQAHSSVEKAGLISLVKIKFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDKLSELGPICAREGLWLHVDAAYAGTAFLRPELRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSIKLWFVIRSFGVKNLQAHVRHGTDMAKYFESLVRSDPVFEIPAERHLGLVVFRLKGPNCLTESVLKEIAKTGQVFLIPATIQDKLIIRFTVTSQFTTKDDILRDWNLIREAANLVLSQHCTSQPSPRAKNLIPPPVTRDSKDLTNGLSLESVNEGGDDPVQVRKIFRLPGDSLETTMDPFDDCFSEEASDTTKHKLSSFLFSYLSVQNKKKTMRSLSCNSMPMSAQKSPPPDASVKHGGFFRARIFSGFPEEMMMMKKGGFKKLIKFYSVPSFPECSSQCGTLQLPCCPLQAMV
uniprot
proteins
ec_number
4.1.1.22
uniprot
proteins
function
FUNCTION: Catalyzes the biosynthesis of histamine from histidine. {ECO:0000250}.
uniprot
proteins
mass_dalton
73636
uniprot
proteins
pathway_participation
PATHWAY: Amine and polyamine biosynthesis; histamine biosynthesis; histamine from L-histidine: step 1/1.
uniprot
proteins
post_translational_modification
PTM: May be post-translationally processed.
uniprot
proteins
protein_family
Group II decarboxylase family
uniprot
proteins
pubmed
1702422
uniprot
proteins
pubmed
2300558
uniprot
proteins
pubmed
2402512
uniprot
proteins
sequence_length
656
uniprot
proteins