TMEM214
entrez
54867
canonical
uniprot
Q6NUQ4
canonical
ensembl
ENSG00000119777
resolver
ensp
ENSP00000238788
resolver
ensp
ENSP00000384417
resolver
ensp
ENSP00000392442
resolver
ensp
ENSP00000395061
resolver
enst
ENST00000435172
resolver
genesymbol
TMEM214
resolver
hgnc
HGNC:25983
resolver
uniprot
A6NNF2
resolver
uniprot
B3KUI9
resolver
uniprot
B5MCD8
resolver
uniprot
D6W547
resolver
uniprot
H7C0H8
resolver
uniprot
Q53SW1
resolver
uniprot
Q69YH4
resolver
uniprot
Q8NC45
resolver
uniprot
Q8WZ37
resolver
uniprot
Q9NXH2
resolver
uniprot_entry
H7C0H8_HUMAN
resolver
uniprot_entry
TM214_HUMAN
resolver
uniprot_sec
A6NNF2
resolver
uniprot_sec
B3KUI9
resolver
uniprot_sec
B5MCD8
resolver
uniprot_sec
D6W547
resolver
uniprot_sec
Q53SW1
resolver
uniprot_sec
Q69YH4
resolver
uniprot_sec
Q8NC45
resolver
uniprot_sec
Q8WZ37
resolver
uniprot_sec
Q9NXH2
resolver
amino_acid_sequence
MATKTAGVGRWEVVKKGRRPGVGAGAGGRGGGRNRRALGEANGVWKYDLTPAIQTTSTLYERGFENIMKRQNKEQVPPPAVEPKKPGNKKQPKKVATPPNQNQKQGRFRSLEEALKALDVADLQKELDKSQSVFSGNPSIWLKDLASYLNYKLQAPLSEPTLSQHTHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIATANLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAITYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPDSTLHTYFPSFLSRATPSCPPEMKKELLSSLTECLTVDPLSASVWRQLYPKHLSQSSLLLEHLLSSWEQIPKKVQKSLQETIQSLKLTNQELLRKGSSNNQDVVTCDMACKGLLQQVQGPRLPWTRLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLRSSGFLPASQQACAKLYSYSLQGYSWLGETLPLWGSHLLTVVRPSLQLAWAHTNATVSFLSAHCASHLAWFGDSLTSLSQRLQIQLPDSVNQLLRYLRELPLLFHQNVLLPLWHLLLEALAWAQEHCHEACRGEVTWDCMKTQLSEAVHWTWLCLQDITVAFLDWALALISQQ
uniprot
proteins
function
FUNCTION: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. {ECO:0000269|PubMed:23661706}.
uniprot
proteins
mass_dalton
77151
uniprot
proteins
protein_family
TMEM214 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15498874
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23661706
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
689
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:23661706}; Multi-pass membrane protein {ECO:0000269|PubMed:23661706}.
uniprot
proteins
transmembrane_region
TRANSMEM 480..500; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 616..636; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins