Sez6
entrez
20370
canonical
uniprot
Q7TSK2
canonical
ensembl
ENSMUSG00000000632
resolver
ensp
ENSMUSP00000000646
resolver
ensp
ENSMUSP00000091532
resolver
ensp
ENSMUSP00000233181
resolver
ensp
ENSMUSP00000233183
resolver
genesymbol
Sez6
resolver
genesymbol_syn
Kiaa4158
resolver
uniprot
Q3TT53
resolver
uniprot
Q62223
resolver
uniprot
Q62224
resolver
uniprot
Q62269
resolver
uniprot
Q7TPC9
resolver
uniprot_entry
SEZ6_MOUSE
resolver
uniprot_sec
Q3TT53
resolver
uniprot_sec
Q62223
resolver
uniprot_sec
Q62224
resolver
uniprot_sec
Q62269
resolver
uniprot_sec
Q7TPC9
resolver
amino_acid_sequence
MRPAALLLLPSLLALLAHGLSSEAPITGEGHATGIRETDGELTAAPTPEQSDRGVHFVTTAPTLKLLNHHPLLEEFLQEGLEREEAPQPALPFQPDSPTHFTPSPLPRLTNQDNRPVFTSPTPAVAAAPTQPHSREKPWNLESKPPELSITSSLPPGPSMAVPTLLPEDRPSTTPPSQAWTPTQEGPGDMDRPWVPEVMSKTTGLGVEGTIATSTASGDDEETTTTIITTTVTTVQPPGPCSWNFSGPEGSLDSPTAPSSPSDVGLDCFYYISVYPGYGVEIKVENISLQEGETITVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPLPAGPGTFHFRYQAYLLSCHFPRRPAYGDVTVTSLHPGGSAHFHCATGYQLKGARFLTCLNATQPFWDSQEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSSGRHFFVEFSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLEQGSIIIECVDLHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSGDVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMADVTIQFQSDPGTSALGYQQGFVIHFFEVPRNDTCPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDRQAGSPKWSDRAPKCLLEQFKPCHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNGRSLDVAKAPAASSALDAAHLAAAIFLPLVAMVLLVGGVYLYFSRFQGKSPLQLPRTHPRPYNRITVESAFDNPTYETGSLSFAGDERI
uniprot
proteins
function
FUNCTION: May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity. {ECO:0000269|PubMed:18031681}.
uniprot
proteins
mass_dalton
107433
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000269|PubMed:7488116}.
uniprot
proteins
protein_family
SEZ6 family
uniprot
proteins
pubmed
12351182
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16814779
uniprot
proteins
pubmed
18031681
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7488116
uniprot
proteins
pubmed
7723619
uniprot
proteins
sequence_length
991
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Localized on dendrites and in the postsynaptic fraction. Does not appear to be enriched at synapses, at least not in the presynaptic axon terminal.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single-pass type I membrane protein. Synapse. Cell projection, dendrite. Note=Localized on dendrites and in the synaptic and postsynaptic fraction.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted {ECO:0000305}. Cytoplasm.
uniprot
proteins
transmembrane_region
TRANSMEM 923..943; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins