Extl2
entrez
58193
canonical
uniprot
Q9ES89
canonical
ensembl
ENSMUSG00000027963
resolver
ensp
ENSMUSP00000029575
resolver
ensp
ENSMUSP00000102110
resolver
ensp
ENSMUSP00000102111
resolver
enst
ENSMUST00000029575
resolver
enst
ENSMUST00000106501
resolver
enst
ENSMUST00000106502
resolver
genesymbol
Extl2
resolver
genesymbol_syn
Extr2
resolver
uniprot
F7A372
resolver
uniprot
Q3TSR0
resolver
uniprot
Q505Q8
resolver
uniprot
Q8C089
resolver
uniprot
Q9CX90
resolver
uniprot_entry
EXTL2_MOUSE
resolver
uniprot_entry
F7A372_MOUSE
resolver
uniprot_entry
Q3TSR0_MOUSE
resolver
uniprot_entry
Q8C089_MOUSE
resolver
uniprot_sec
Q505Q8
resolver
uniprot_sec
Q9CX90
resolver
amino_acid_sequence
MMRGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM
uniprot
proteins
ec_number
2.4.1.223
uniprot
proteins
function
FUNCTION: Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. {ECO:0000250|UniProtKB:Q9UBQ6}.
uniprot
proteins
mass_dalton
37391
uniprot
proteins
mutagenesis
MUTAGEN 243; /note="N->A: Reduced activity."; /evidence="ECO:0000269|PubMed:12562774"; MUTAGEN 246; /note="D->A: Abolishes enzyme activity."; /evidence="ECO:0000269|PubMed:12562774"; MUTAGEN 293; /note="R->A: Reduced activity."; /evidence="ECO:0000269|PubMed:12562774
uniprot
proteins
protein_family
Glycosyltransferase 47 family
uniprot
proteins
pubmed
10965119
uniprot
proteins
pubmed
12562774
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
330
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins