Commd4
entrez
66199
canonical
uniprot
Q9CQ02
canonical
ensembl
ENSMUSG00000032299
resolver
ensp
ENSMUSP00000069078
resolver
ensp
ENSMUSP00000205288
resolver
enst
ENSMUST00000065358
resolver
genesymbol
Commd4
resolver
uniprot_entry
COMD4_MOUSE
resolver
amino_acid_sequence
MRFRFCGDLDCPDWVLAEISTLAKISSVKLRLLCSQVLKELLGQGIDYEKILKLTADAKFESGDVKATVAVLSFILSSAAKHSVDSDSLSSELQQLGLPKEHATSLCRCYEEKQSPLQEHLRACSLRVNRLASVGWRVDYTLSSSLLHSVEEPMVHLQLQVVPAPGTQAQPVSMSLSADKFQVLLAELKQAQTMMTALG
uniprot
proteins
function
FUNCTION: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity). Down-regulates activation of NF-kappa-B (By similarity). {ECO:0000250|UniProtKB:Q9H0A8}.
uniprot
proteins
mass_dalton
21860
uniprot
proteins
protein_family
COMM domain-containing protein 4 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
199
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H0A8}. Nucleus {ECO:0000250|UniProtKB:Q9H0A8}.
uniprot
proteins