Dclk2
entrez
310698
canonical
uniprot
Q5MPA9
canonical
ensembl
ENSRNOG00000016550
resolver
ensembl
ENSRNOG00055025208
resolver
ensembl
ENSRNOG00060031672
resolver
ensp
ENSRNOP00000022292
resolver
ensp
ENSRNOP00000062805
resolver
ensp
ENSRNOP00000075203
resolver
ensp
ENSRNOP00000104840
resolver
genesymbol
Dclk2
resolver
genesymbol_syn
Dcamkl2
resolver
genesymbol_syn
Dck2
resolver
uniprot
Q5MPA7
resolver
uniprot
Q5MPA8
resolver
uniprot
Q5MPB0
resolver
uniprot_entry
DCLK2_RAT
resolver
uniprot_sec
Q5MPA7
resolver
uniprot_sec
Q5MPA8
resolver
uniprot_sec
Q5MPB0
resolver
amino_acid_sequence
MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSISGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTVDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNVNPNWSVNIKGGTTRTLAVASAKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKYRYAQDDFVLDHSECRVLKSSYSRASAAKYSGSRSPGLSRRSKSPASVKRAGHSSAYSTAKSPVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISAQGRSSSNVNGGPELDRCMSPEGVNGNRCSESFTLLEKYRIGKVIGDGNFAVVKECMDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETTTELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLASALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGEILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQVFCSKHCRDSSKSSREQTSAREAPPPPESPRPPGPPATSGCDPAGTWRRHRD
uniprot
proteins
ec_number
2.7.11.1
uniprot
proteins
function
FUNCTION: Protein kinase with a significantly reduced Ca(2+)+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
84016
uniprot
proteins
mutagenesis
MUTAGEN 438; /note="K->A: Loss of autophosphorylation."; /evidence="ECO:0000269|PubMed:15611072
uniprot
proteins
post_translational_modification
PTM: Autophosphorylated.
uniprot
proteins
protein_family
CAMK Ser/Thr protein kinase family
uniprot
proteins
protein_family
CaMK subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
pubmed
15611072
uniprot
proteins
pubmed
16641100
uniprot
proteins
sequence_length
767
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15611072}. Note=Colocalizes with microtubules. When overexpressed in sympathetic neurons, localizes to cell body and to the terminal segments of axons and dendrites.
uniprot
proteins