Kctd1
entrez
106931
canonical
uniprot
Q5M956
canonical
ensembl
ENSMUSG00000036225
resolver
ensp
ENSMUSP00000025992
resolver
ensp
ENSMUSP00000128070
resolver
enst
ENSMUST00000168989
resolver
genesymbol
Kctd1
resolver
uniprot
E9Q6T9
resolver
uniprot
Q5EER9
resolver
uniprot_entry
E9Q6T9_MOUSE
resolver
uniprot_entry
KCTD1_MOUSE
resolver
uniprot_sec
Q5EER9
resolver
amino_acid_sequence
MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELRRTPRVPSVIRIKQEPLD
uniprot
proteins
function
FUNCTION: Is a regulator of different signaling pathways. Up-regulates ADCY5 thereby enhancing cAMP signaling, and is involved in the negative regulation of Wnt canonical, Hh and Notch signaling (By similarity). Is a repressor of transcriptional activation mediated by AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent (By similarity). {ECO:0000250|UniProtKB:Q719H9}.
uniprot
proteins
mass_dalton
29405
uniprot
proteins
post_translational_modification
PTM: Sumoylated. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
38791218
uniprot
proteins
sequence_length
257
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q719H9}.
uniprot
proteins