TMEM161B
entrez
153396
canonical
uniprot
Q8NDZ6
canonical
ensembl
ENSG00000164180
resolver
ensp
ENSP00000296595
resolver
ensp
ENSP00000421498
resolver
ensp
ENSP00000425991
resolver
ensp
ENSP00000426354
resolver
ensp
ENSP00000520925
resolver
ensp
ENSP00000669554
resolver
enst
ENST00000512429
resolver
enst
ENST00000514135
resolver
enst
ENST00000850886
resolver
genesymbol
TMEM161B
resolver
hgnc
HGNC:28483
resolver
uniprot
A0ABB0MVN1
resolver
uniprot
B7Z6T3
resolver
uniprot
B7Z6X1
resolver
uniprot
E9PCX5
resolver
uniprot
F6SD43
resolver
uniprot
Q5CZH7
resolver
uniprot
Q6UWQ6
resolver
uniprot_entry
B7Z6T3_HUMAN
resolver
uniprot_entry
B7Z6X1_HUMAN
resolver
uniprot_entry
E9PCX5_HUMAN
resolver
uniprot_entry
F6SD43_HUMAN
resolver
uniprot_entry
T161B_HUMAN
resolver
uniprot_sec
A0ABB0MVN1
resolver
uniprot_sec
Q5CZH7
resolver
uniprot_sec
Q6UWQ6
resolver
amino_acid_sequence
MGVIGIQLVVTMVMASVMQKIIPHYSLARWLLCNGSLRWYQHPTEEELRILAGKQQKGKTKKDRKYNGHIESKPLTIPKDIDLHLETKSVTEVDTLALHYFPEYQWLVDFTVAATVVYLVTEVYYNFMKPTQEMNISLVWCLLVLSFAIKVLFSLTTHYFKVEDGGERSVCVTFGFFFFVKAMAVLIVTENYLEFGLETGFTNFSDSAMQFLEKQGLESQSPVSKLTFKFFLAIFCSFIGAFLTFPGLRLAQMHLDALNLATEKITQTLLHINFLAPLFMVLLWVKPITKDYIMNPPLGKESIPLMTEATFDTLRLWLIILLCALRLAMMRSHLQAYLNLAQKCVDQMKKEAGRISTVELQKMVARVFYYLCVIALQYVAPLVMLLHTTLLLKTLGNHSWGIYPESISTLPVDNSLLSNSVYSELPSAEGKMKVTVTQITVALSSLKNIFTPLLFRGLLSFLTWWIAACLFSTSLFGLFYHQYLTVA
uniprot
proteins
function
FUNCTION: Essential for maintaining normal cardiac rhythm in the developing heart and for neonatal survival (By similarity). Inhibits potassium and calcium currents in the cardiomyocytes, this assists in timely action potential repolarization and thereby maintains normal cardiac rhythm (By similarity). {ECO:0000250|UniProtKB:Q8C2L6}.
uniprot
proteins
mass_dalton
55482
uniprot
proteins
protein_family
TMEM161 family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
487
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7SY10}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 107..127; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 169..189; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 228..248; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 265..285; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 305..325; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 367..387; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 459..479; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins