Slc25a20
entrez
57279
canonical
uniprot
Q9Z2Z6
canonical
ensembl
ENSMUSG00000032602
resolver
ensp
ENSMUSP00000035222
resolver
enst
ENSMUST00000035222
resolver
genesymbol
Slc25a20
resolver
genesymbol_syn
Cac
resolver
genesymbol_syn
Cact
resolver
uniprot
Q3U801
resolver
uniprot_entry
MCAT_MOUSE
resolver
uniprot_sec
Q3U801
resolver
amino_acid_sequence
MADEPKPISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKSPEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGENKYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPEGKSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFLNWIAPNL
uniprot
proteins
function
FUNCTION: Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism. Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation. Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange). {ECO:0000250|UniProtKB:O43772}.
uniprot
proteins
mass_dalton
33027
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19287344
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
301
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 13..31; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 74..93; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 113..131; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 171..190; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 212..230; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 268..287; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins