DPY30
entrez
84661
canonical
uniprot
Q9C005
canonical
ensembl
ENSG00000162961
resolver
ensp
ENSP00000295066
resolver
ensp
ENSP00000345837
resolver
ensp
ENSP00000543219
resolver
ensp
ENSP00000543221
resolver
ensp
ENSP00000593036
resolver
ensp
ENSP00000593039
resolver
ensp
ENSP00000593041
resolver
ensp
ENSP00000593042
resolver
ensp
ENSP00000759337
resolver
ensp
ENSP00000759338
resolver
ensp
ENSP00000759344
resolver
enst
ENST00000295066
resolver
enst
ENST00000342166
resolver
enst
ENST00000873160
resolver
enst
ENST00000873162
resolver
enst
ENST00000922977
resolver
enst
ENST00000922980
resolver
enst
ENST00000922982
resolver
enst
ENST00000922983
resolver
genesymbol
DPY30
resolver
hgnc
HGNC:24590
resolver
uniprot
D6W578
resolver
uniprot_entry
DPY30_HUMAN
resolver
uniprot_sec
D6W578
resolver
amino_acid_sequence
MEPEQMLEGQTQVAENPHSEYGLTDNVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFEDRN
uniprot
proteins
function
FUNCTION: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. {ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:19651892, ECO:0000269|PubMed:21335234}.
uniprot
proteins
mass_dalton
11250
uniprot
proteins
protein_family
Dpy-30 family
uniprot
proteins
pubmed
14992727
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17500065
uniprot
proteins
pubmed
18838538
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19481096
uniprot
proteins
pubmed
19556245
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19651892
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21335234
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
28112733
uniprot
proteins
sequence_length
99
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19651892}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:19651892}. Note=Associated with chromatin at regions enriched in histone H3 trimethylated at 'Lys-4. Highly enriched in gene promoter regions and 5' UTRs, but not in downstream regions of genes or 3' UTRs (By similarity). {ECO:0000250}.
uniprot
proteins