Coro7
entrez
78885
canonical
uniprot
Q9D2V7
canonical
ensembl
ENSMUSG00000039637
resolver
ensp
ENSMUSP00000048489
resolver
enst
ENSMUST00000038552
resolver
genesymbol
Coro7
resolver
uniprot
Q3UDJ4
resolver
uniprot
Q6P8Y8
resolver
uniprot
Q8C9V7
resolver
uniprot_entry
CORO7_MOUSE
resolver
uniprot_sec
Q3UDJ4
resolver
uniprot_sec
Q6P8Y8
resolver
uniprot_sec
Q8C9V7
resolver
amino_acid_sequence
MSRFKVSKFRHMEARPSRREAWISDIRAVTTPTCGNHIKSSCSLIAFNSDRPGVLGVISLEGHEENKRHVTYLGCHSDLVTDLDFSPFDDFLLASGSADRTIKLWRLSGTGEALPSVPGVVLGPEELPVEVLQFHPTVDGVLVSTAGKTVKVWDVAKQQPLTELEAHKDLVQSAVWSRDGAIVGTACKDKQLRIFDPRARTQASQSTQAHENNRDIRLAWTGIQEHLVSTGFNQMREREAKLWDTRLFSSALASVTLDTSPGPLIPLLDPDSGLLVLAGKGENQLYCYEVTPQQPALSPVTQCILENVLRGAALVPRRALAVMSCEVLQVLQLSDTAIIPISHHVPRKAVEFHEDLFPDTAGSVPASDAHMWWAGDNQQVQKVSLNPARRPHPCFTSSLVPTMEPAPDMVQPAEMPRADTDLSEGFSSPSSLMSPSTPSSLGPSLSSTSGIGTSPSQRSLQSLLGPSSKFRHTQGSLLHRDSHITNLKGLNLTTPGESDGFCANRLRVAVPLLSSGGQVAVLELQKPGRLPDTALPTLQNGTAVMDLVWDPFDPHRLAVAGEDARIRLWRVPPGGLENVLTTPETVLTGHTEKIYSLRFHPLAADVLASSSYDLTVRIWDLQTGAERLKLQGHQDQIFSLAWSPDGKQLATVCKDGHVRVYEPRSSPLPLQEGPGPEGGRGARIVWVCDGGCLLVSGFDSRSERQLQLYIADALAQGPSALLGLDVAPSTLLPSYDPDTGLVLLTGKGDTRVFLYEVLPEAPFFLECNSFTSPDPHKGFVLLPKTECDIQDVEFARCLRLRQTSLEPVAFRLPRVRKEFFQDDVFPDTAVTWEPALSAKAWFEGANGQPRLLSLQPPGMTPVSQAPREVPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDPLPQDSFEGVDEDEWD
uniprot
proteins
function
FUNCTION: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
100812
uniprot
proteins
post_translational_modification
PTM: The membrane-associated form is phosphorylated on tyrosine residues.; PTM: Ubiquitinated via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex: 'Lys-33'-linked ubiquitination promotes interaction with EPS15 and facilitates actin polymerization at the trans-Golgi network, thereby facilitating post-Golgi trafficking. Deubiquitinated by ZRANB1/TRABID (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
WD repeat coronin family
uniprot
proteins
pubmed
15327992
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
922
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:15327992}. Golgi apparatus, trans-Golgi network {ECO:0000250}. Cytoplasmic vesicle {ECO:0000269|PubMed:15327992}. Cytoplasm, cytosol {ECO:0000269|PubMed:15327992}. Note=Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments.
uniprot
proteins