DLG2
entrez
1740
canonical
uniprot
Q15700
canonical
ensembl
ENSG00000150672
resolver
ensp
ENSP00000280241
resolver
ensp
ENSP00000365272
resolver
ensp
ENSP00000381353
resolver
ensp
ENSP00000381355
resolver
ensp
ENSP00000385113
resolver
ensp
ENSP00000393049
resolver
ensp
ENSP00000402275
resolver
ensp
ENSP00000432894
resolver
ensp
ENSP00000433848
resolver
ensp
ENSP00000435809
resolver
ensp
ENSP00000435849
resolver
ensp
ENSP00000497475
resolver
ensp
ENSP00000497771
resolver
ensp
ENSP00000500169
resolver
ensp
ENSP00000516282
resolver
ensp
ENSP00000516284
resolver
ensp
ENSP00000516287
resolver
ensp
ENSP00000516288
resolver
ensp
ENSP00000516291
resolver
ensp
ENSP00000516312
resolver
ensp
ENSP00000516313
resolver
enst
ENST00000404783
resolver
enst
ENST00000524982
resolver
enst
ENST00000527088
resolver
enst
ENST00000527466
resolver
enst
ENST00000532653
resolver
enst
ENST00000648622
resolver
enst
ENST00000706204
resolver
enst
ENST00000706226
resolver
enst
ENST00000706232
resolver
enst
ENST00000706233
resolver
enst
ENST00000706243
resolver
enst
ENST00000706266
resolver
enst
ENST00000706267
resolver
genesymbol
DLG2
resolver
hgnc
HGNC:2901
resolver
uniprot
A0A3B3ISW2
resolver
uniprot
A0A5F9ZH92
resolver
uniprot
A0A994J570
resolver
uniprot
A0A994J587
resolver
uniprot
A0A994J5T6
resolver
uniprot
A0A994J7P1
resolver
uniprot
A0A994J7Q5
resolver
uniprot
A0A994J819
resolver
uniprot
A0A994J822
resolver
uniprot
A0ACM8QHE3
resolver
uniprot
B5MCC5
resolver
uniprot
B7WNY8
resolver
uniprot
B7Z2T4
resolver
uniprot
B7Z640
resolver
uniprot
E9PIJ9
resolver
uniprot
E9PN83
resolver
uniprot
F6UPN5
resolver
uniprot
F8W9V6
resolver
uniprot
Q59G57
resolver
uniprot
Q5H9Q4
resolver
uniprot
Q68CQ8
resolver
uniprot
Q6ZTA8
resolver
uniprot_entry
A0A3B3ISW2_HUMAN
resolver
uniprot_entry
A0A5F9ZH92_HUMAN
resolver
uniprot_entry
A0A994J570_HUMAN
resolver
uniprot_entry
A0A994J587_HUMAN
resolver
uniprot_entry
A0A994J5T6_HUMAN
resolver
uniprot_entry
A0A994J7P1_HUMAN
resolver
uniprot_entry
A0A994J7Q5_HUMAN
resolver
uniprot_entry
A0A994J819_HUMAN
resolver
uniprot_entry
A0A994J822_HUMAN
resolver
uniprot_entry
A0ACM8QHE3_HUMAN
resolver
uniprot_entry
B5MCC5_HUMAN
resolver
uniprot_entry
B7Z2T4_HUMAN
resolver
uniprot_entry
DLG2_HUMAN
resolver
uniprot_entry
E9PIJ9_HUMAN
resolver
uniprot_entry
E9PN83_HUMAN
resolver
uniprot_entry
F6UPN5_HUMAN
resolver
uniprot_sec
B7WNY8
resolver
uniprot_sec
B7Z640
resolver
uniprot_sec
F8W9V6
resolver
uniprot_sec
Q59G57
resolver
uniprot_sec
Q5H9Q4
resolver
uniprot_sec
Q68CQ8
resolver
uniprot_sec
Q6ZTA8
resolver
amino_acid_sequence
MFFACYCALRTNVKKYRYQDEDAPHDHSLPRLTHEVRGPELVHVSEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPYVNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPPDITHSYSPPMENHLLSGNNGTLEYKTSLPPISPGRYSPIPKHMLVDDDYTRPPEPVYSTVNKLCDKPASPRHYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVTRQEINYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPSKEKL
uniprot
proteins
function
FUNCTION: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
97552
uniprot
proteins
post_translational_modification
PTM: Palmitoylation of isoform 1 is not required for targeting to postsynaptic density. {ECO:0000250}.
uniprot
proteins
protein_family
MAGUK family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15304517
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
16630835
uniprot
proteins
pubmed
17384233
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19118189
uniprot
proteins
pubmed
19807924
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
8755482
uniprot
proteins
sequence_length
870
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q63622}; Lipid-anchor {ECO:0000250|UniProtKB:Q63622}. Postsynaptic density {ECO:0000250|UniProtKB:Q63622}. Synapse {ECO:0000250}. Membrane {ECO:0000250|UniProtKB:Q63622}. Cell projection, axon {ECO:0000250|UniProtKB:Q63622}. Perikaryon {ECO:0000250|UniProtKB:Q63622}. Note=Concentrated in soma and postsynaptic density of a subset of neurons. {ECO:0000250|UniProtKB:Q63622}.
uniprot
proteins