NUPR2
entrez
389493
canonical
uniprot
A6NF83
canonical
ensembl
ENSG00000185290
resolver
ensp
ENSP00000455442
resolver
enst
ENST00000329309
resolver
genesymbol
NUPR2
resolver
genesymbol_syn
NUPR1L
resolver
hgnc
HGNC:44164
resolver
uniprot_entry
NUPR2_HUMAN
resolver
amino_acid_sequence
MEAPAERALPRLQALARPPPPISYEEELYDCLDYYYLRDFPACGAGRSKGRTRREQALRTNWPAPGGHERKVAQKLLNGQRKRRQRQLHPKMRTRLT
uniprot
proteins
function
FUNCTION: Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells (PubMed:25899918). Involved in the G1 cell cycle arrest, and in a decrease in cell viability and cell proliferation (PubMed:25899918). Plays a role as a negative regulator of the protumoral factor NUPR1 (PubMed:25899918). {ECO:0000269|PubMed:25899918}.
uniprot
proteins
mass_dalton
11356
uniprot
proteins
protein_family
NUPR family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
25899918
uniprot
proteins
sequence_length
97
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:25899918}.
uniprot
proteins