Eda2r
entrez
245527
canonical
uniprot
Q8BX35
canonical
ensembl
ENSMUSG00000034457
resolver
ensp
ENSMUSP00000041210
resolver
ensp
ENSMUSP00000109463
resolver
enst
ENSMUST00000037353
resolver
enst
ENSMUST00000113832
resolver
genesymbol
Eda2r
resolver
genesymbol_syn
Tnfrsf27
resolver
genesymbol_syn
Xedar
resolver
uniprot
Q3KP88
resolver
uniprot
Q8BM50
resolver
uniprot_entry
Q3KP88_MOUSE
resolver
uniprot_entry
TNR27_MOUSE
resolver
uniprot_sec
Q8BM50
resolver
amino_acid_sequence
MDCQENEYRDQWGRCVTCQQCGPGQELSKDCGYGEGGDAHCIVCPPRKYKSTWGHHRCQTCITCAVINRVQKANCTNTSNAICGDCLPRFYRKTRIGGLQDQECIPCTKQTPSSEVQCTFQLSLVKVDAHTVPPREATLVALVGSLLVVFALAFLGLFFLYCKQIFNRHCQCRDSLQYEAEKTVEEDSLFPVPPGQETSPEFPANEGILEIKPLNSILDDDCSSTRGFPTQESFTMASCASESHSQWVHTPIECTELDLQKFSSSIPSTGPETLRENTAEHSGDRLELYVPFEVPSL
uniprot
proteins
function
FUNCTION: Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33066
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 139..159; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins