MRGPRX3
entrez
117195
canonical
uniprot
Q96LB0
canonical
ensembl
ENSG00000179826
resolver
ensp
ENSP00000379571
resolver
ensp
ENSP00000481943
resolver
enst
ENST00000396275
resolver
enst
ENST00000621697
resolver
genesymbol
MRGPRX3
resolver
genesymbol_syn
MRGX3
resolver
genesymbol_syn
SNSR1
resolver
genesymbol_syn
SNSR2
resolver
hgnc
HGNC:17980
resolver
uniprot
B0M0L1
resolver
uniprot
Q8TDE0
resolver
uniprot
Q8TDE1
resolver
uniprot_entry
MRGX3_HUMAN
resolver
uniprot_sec
B0M0L1
resolver
uniprot_sec
Q8TDE0
resolver
uniprot_sec
Q8TDE1
resolver
amino_acid_sequence
MDSTIPVLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNAVSIYILNLVAADFLFLSGHIICSPLRLINIRHPISKILSPVMTFPYFIGLSMLSAISTERCLSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFCDFLFSGANSVWCETSDFITIAWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQWALFSRIHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDTPEVDEGGGWLPQETLELSGSRLEQ
uniprot
proteins
function
FUNCTION: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
36483
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
protein_family
Mas subfamily
uniprot
proteins
pubmed
11551509
uniprot
proteins
pubmed
11850634
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
sequence_length
322
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 32..52; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 61..81; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 97..117; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 178..198; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 214..234; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 255..275; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins