CXCL3
entrez
2921
canonical
uniprot
P19876
canonical
ensembl
ENSG00000163734
resolver
ensp
ENSP00000296026
resolver
enst
ENST00000296026
resolver
genesymbol
CXCL3
resolver
genesymbol_syn
GRO3
resolver
genesymbol_syn
GROG
resolver
genesymbol_syn
SCYB3
resolver
hgnc
HGNC:4604
resolver
uniprot
Q4W5H9
resolver
uniprot_entry
CXCL3_HUMAN
resolver
uniprot_sec
Q4W5H9
resolver
amino_acid_sequence
MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
uniprot
proteins
function
FUNCTION: Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. {ECO:0000250, ECO:0000269|PubMed:10095777}.
uniprot
proteins
mass_dalton
11342
uniprot
proteins
post_translational_modification
PTM: N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. {ECO:0000269|PubMed:10095777}.
uniprot
proteins
protein_family
Intercrine alpha (chemokine CxC) family
uniprot
proteins
pubmed
10095777
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
2201751
uniprot
proteins
pubmed
2217207
uniprot
proteins
sequence_length
107
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins