MPP3
entrez
4356
canonical
uniprot
Q13368
canonical
ensembl
ENSG00000161647
resolver
ensp
ENSP00000381425
resolver
ensp
ENSP00000381430
resolver
ensp
ENSP00000671575
resolver
ensp
ENSP00000686559
resolver
ensp
ENSP00000782000
resolver
enst
ENST00000398393
resolver
genesymbol
MPP3
resolver
genesymbol_syn
DLG3
resolver
hgnc
HGNC:7221
resolver
uniprot
A0A0C4DGP3
resolver
uniprot
B2R7N0
resolver
uniprot
D3DX46
resolver
uniprot
D3DX47
resolver
uniprot
Q4GX05
resolver
uniprot
Q6PGR3
resolver
uniprot
Q86SV1
resolver
uniprot_entry
D3DX46_HUMAN
resolver
uniprot_entry
MPP3_HUMAN
resolver
uniprot_sec
A0A0C4DGP3
resolver
uniprot_sec
B2R7N0
resolver
uniprot_sec
D3DX47
resolver
uniprot_sec
Q4GX05
resolver
uniprot_sec
Q6PGR3
resolver
uniprot_sec
Q86SV1
resolver
amino_acid_sequence
MPVLSEDSGLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR
uniprot
proteins
function
FUNCTION: Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K) (PubMed:24503895). Stabilizes HTR2C at the plasma membrane and prevents its desensitization. May participates in the maintenance of adherens junctions (By similarity). {ECO:0000250|UniProtKB:O88910, ECO:0000269|PubMed:24503895}.
uniprot
proteins
mass_dalton
66152
uniprot
proteins
protein_family
MAGUK family
uniprot
proteins
pubmed
13679854
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16519681
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
24503895
uniprot
proteins
pubmed
25268382
uniprot
proteins
pubmed
8824795
uniprot
proteins
sequence_length
585
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24503895}. Apical cell membrane {ECO:0000269|PubMed:16519681}. Cell junction, adherens junction {ECO:0000269|PubMed:16519681}. Note=Localized in apical villi of Mueller glia cells (By similarity). Localized at the apical membrane in the developing cortex and colocalized with apical proteins and adherens junction proteins (By similarity). Localized at the outer limiting membrane (OLM), and outer plexiform (OPL) of retina (PubMed:16519681). {ECO:0000250|UniProtKB:O88910, ECO:0000269|PubMed:16519681}.
uniprot
proteins