Kyat1
entrez
70266
canonical
uniprot
Q8BTY1
canonical
ensembl
ENSMUSG00000039648
resolver
ensp
ENSMUSP00000038612
resolver
ensp
ENSMUSP00000109291
resolver
ensp
ENSMUSP00000109292
resolver
ensp
ENSMUSP00000109293
resolver
enst
ENSMUST00000044038
resolver
enst
ENSMUST00000113661
resolver
enst
ENSMUST00000113662
resolver
enst
ENSMUST00000113663
resolver
genesymbol
Kyat1
resolver
genesymbol_syn
Ccbl1
resolver
genesymbol_syn
Kat
resolver
uniprot
Q05CI8
resolver
uniprot
Q8BY27
resolver
uniprot_entry
KAT1_MOUSE
resolver
uniprot_entry
Q05CI8_MOUSE
resolver
uniprot_sec
Q8BY27
resolver
amino_acid_sequence
MSKQLQARRLEGIDHNPWVEFTRLSKEYDVVNLGQGFPDFSPPDFAVQAFQQATTGNFMLNQYTSAFGYPPLTKILASFFGKLLGQEMDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLSPAPKGQLGSSNDWQLDPTELASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMGLNRDHMIQSLQSVGLKPLIPQGSYFLIADISDFKSSMPDLPGAMDEPYDTRFAKWMIKNKGLSAIPVSTFYSQPHHKDFDHYIRFCFVKDKATLQAMDKRLCSWKGEPQA
uniprot
proteins
ec_number
2.6.1.64
uniprot
proteins
ec_number
2.6.1.7
uniprot
proteins
ec_number
4.4.1.13
uniprot
proteins
function
FUNCTION: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. {ECO:0000250|UniProtKB:Q16773}.
uniprot
proteins
mass_dalton
47564
uniprot
proteins
pathway_participation
PATHWAY: Amino-acid degradation; L-kynurenine degradation; kynurenate from L-kynurenine: step 1/2.
uniprot
proteins
protein_family
Class-I pyridoxal-phosphate-dependent aminotransferase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
424
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q16773}.
uniprot
proteins