Panx3
entrez
315567
canonical
uniprot
P60572
canonical
ensembl
ENSRNOG00000031675
resolver
ensembl
ENSRNOG00055009540
resolver
ensembl
ENSRNOG00060011794
resolver
ensembl
ENSRNOG00065016203
resolver
ensp
ENSRNOP00000041185
resolver
ensp
ENSRNOP00055012965
resolver
ensp
ENSRNOP00060015671
resolver
ensp
ENSRNOP00065021209
resolver
enst
ENSRNOT00000042717
resolver
enst
ENSRNOT00055016135
resolver
enst
ENSRNOT00060019954
resolver
enst
ENSRNOT00065026971
resolver
genesymbol
Panx3
resolver
genesymbol_syn
Px3
resolver
uniprot_entry
PANX3_RAT
resolver
amino_acid_sequence
MSLAHTAAEYMLSDALLPDRRGSRLKGLRLELPLDKMVKFVTVGFPLLLMSLAFAQEFSSGSPISCFSPSNFSVRQAVFVDSSCWDSLAHYKQDEAGQYTVKSLWPHKALPYSLLALAVAMYLPVLLWQYAAVPALSSDLLFIISELDKSYNRSIRLVQHMLKIRQKSSDPHVFWDELEKARKERYFEFPLLERYLACKQRSHWLVATYLLRNALLLLFTSATYLYLGHFHLDVFFQEEFSCSIKTGLLHEETHVPELITCRLTSLSVFQIVSVSSVAIYTVLVPVIIYNLTRLCRWDKRLLSIYEMLPAFDLLSRKMLGCPINDLNVILLFLRANISELISFSWLSVLCVLKDTTTQKHNIDTVVDFMTLLAGLEPSKPKHLTQHTYDEHP
uniprot
proteins
function
FUNCTION: Regulator of osteoblast differentiation by functioning as a Ca(2+) channel in the endoplasmic reticulum which regulates calmodulin (CaM) pathways. Allows ATP release into the extracellular space and activation or purinergic receptors. {ECO:0000250|UniProtKB:Q8CEG0}.
uniprot
proteins
mass_dalton
44978
uniprot
proteins
protein_family
Pannexin family
uniprot
proteins
pubmed
14597722
uniprot
proteins
sequence_length
392
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8CEG0}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}. Cell junction, gap junction {ECO:0000250|UniProtKB:Q8CEG0}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8CEG0}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00351}.
uniprot
proteins
transmembrane_region
TRANSMEM 40..60; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351"; TRANSMEM 114..134; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351"; TRANSMEM 216..236; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351"; TRANSMEM 268..288; /note="Helical"; /evidence="ECO:0000255|PROSITE-ProRule:PRU00351
uniprot
proteins