PDZK1IP1
entrez
10158
canonical
uniprot
Q13113
canonical
ensembl
ENSG00000162366
resolver
ensp
ENSP00000294338
resolver
ensp
ENSP00000360952
resolver
ensp
ENSP00000579829
resolver
ensp
ENSP00000579830
resolver
enst
ENST00000294338
resolver
enst
ENST00000371885
resolver
enst
ENST00000909770
resolver
enst
ENST00000909771
resolver
genesymbol
PDZK1IP1
resolver
genesymbol_syn
MAP17
resolver
hgnc
HGNC:16887
resolver
uniprot
Q6ICT9
resolver
uniprot
Q96EI1
resolver
uniprot_entry
PDZ1I_HUMAN
resolver
uniprot_sec
Q6ICT9
resolver
uniprot_sec
Q96EI1
resolver
amino_acid_sequence
MSALSLLILGLLTAVPPASCQQGLGNLQPWMQGLIAVAVFLVLVAIAFAVNHFWCQEEPEPAHMILTVGNKADGVLVGTDGRYSSMAASFRSSEHENAYENVPEEEGKVRSTPM
uniprot
proteins
function
FUNCTION: Auxiliary protein of electrogenic Na(+)-coupled sugar symporter SLC5A2/SGLT2 and SLC5A1/SGLT1 (PubMed:34880493, PubMed:37217492, PubMed:38057552). Essential for the transporter activity of SLC5A2/SGLT2 but not SLC5A1/SGLT1 (PubMed:37217492). {ECO:0000269|PubMed:34880493, ECO:0000269|PubMed:37217492, ECO:0000269|PubMed:38057552}.
uniprot
proteins
mass_dalton
12227
uniprot
proteins
protein_family
PDZK1-interacting protein 1/SMIM24 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
34880493
uniprot
proteins
pubmed
37217492
uniprot
proteins
pubmed
38057552
uniprot
proteins
pubmed
8701988
uniprot
proteins
pubmed
9461128
uniprot
proteins
pubmed
9815914
uniprot
proteins
sequence_length
114
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000305|PubMed:34880493, ECO:0000305|PubMed:37217492, ECO:0000305|PubMed:38057552, ECO:0000305|PubMed:8701988}; Single-pass membrane protein {ECO:0000269|PubMed:34880493, ECO:0000269|PubMed:37217492, ECO:0000269|PubMed:38057552}.
uniprot
proteins
transmembrane_region
TRANSMEM 29..51; /note="Helical"; /evidence="ECO:0000269|PubMed:34880493, ECO:0000269|PubMed:37217492, ECO:0000269|PubMed:38057552, ECO:0007744|PDB:7VSI, ECO:0007744|PDB:7YNI, ECO:0007744|PDB:7YNJ, ECO:0007744|PDB:7YNK, ECO:0007744|PDB:8HB0, ECO:0007744|PDB:8HDH, ECO:0007744|PDB:8HEZ, ECO:0007744|PDB:8HG7, ECO:0007744|PDB:8HIN
uniprot
proteins