Tmem177
entrez
66343
canonical
uniprot
Q8BPE4
canonical
ensembl
ENSMUSG00000036975
resolver
ensp
ENSMUSP00000042416
resolver
enst
ENSMUST00000037906
resolver
genesymbol
Tmem177
resolver
uniprot_entry
TM177_MOUSE
resolver
amino_acid_sequence
MAGPLWRAAAFIQRHRTSLLVGSCAGLFGVQISFHLFPDPIVQWLYQYWPQGQPAPLSPHLWSLFQEVLKDIGVPSGHCYKPFTAFTFQPVSAGFPRLPAGAVVGIPAIFLGGPVTNIEHSVIIHGQRVDWQSPAGTRLRDALTMSHNAQKFALAKEVVYLESGVAALQTLPAPACLAGTWAISVGAKHALGLYGGPMSLRTAFNLVAIVVGYVAYTFSKDSLTLALEGWLDRRTASLSAAYVQGGVEFYEKILSGNLALRSLLGRQGEKLYTPSGNIVPRHWFRINHLPYTTRRDSLQQMWRATVSPGRF
uniprot
proteins
function
FUNCTION: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein. {ECO:0000250|UniProtKB:Q53S58}.
uniprot
proteins
mass_dalton
34067
uniprot
proteins
protein_family
TMEM177 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
311
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q53S58}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 191..211; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins