Pdgfa
entrez
18590
canonical
uniprot
P20033
canonical
ensembl
ENSMUSG00000025856
resolver
ensp
ENSMUSP00000038870
resolver
ensp
ENSMUSP00000075463
resolver
ensp
ENSMUSP00000106521
resolver
ensp
ENSMUSP00000106522
resolver
ensp
ENSMUSP00000169381
resolver
ensp
ENSMUSP00000169385
resolver
enst
ENSMUST00000046901
resolver
enst
ENSMUST00000076095
resolver
enst
ENSMUST00000110896
resolver
enst
ENSMUST00000110897
resolver
genesymbol
Pdgfa
resolver
uniprot
F6VYC3
resolver
uniprot
G5E891
resolver
uniprot
Q99L56
resolver
uniprot_entry
F6VYC3_MOUSE
resolver
uniprot_entry
G5E891_MOUSE
resolver
uniprot_entry
PDGFA_MOUSE
resolver
uniprot_entry
Q99L56_MOUSE
resolver
amino_acid_sequence
MRTWACLLLLGCGYLAHALAEEAEIPRELIERLARSQIHSIRDLQRLLEIDSVGAEDALETSLRAHGSHAINHVPEKRPVPIRRKRSIEEAIPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATSNLNPDHREEETGRRRESGKKRKRKRLKPT
uniprot
proteins
function
FUNCTION: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB. {ECO:0000269|PubMed:10831606, ECO:0000269|PubMed:10903171, ECO:0000269|PubMed:11803579, ECO:0000269|PubMed:19030102, ECO:0000269|PubMed:8681381, ECO:0000269|PubMed:9374392, ECO:0000269|PubMed:9876175}.
uniprot
proteins
mass_dalton
24130
uniprot
proteins
protein_family
PDGF/VEGF growth factor family
uniprot
proteins
pubmed
10831606
uniprot
proteins
pubmed
10903171
uniprot
proteins
pubmed
11803579
uniprot
proteins
pubmed
1340209
uniprot
proteins
pubmed
14514732
uniprot
proteins
pubmed
15207812
uniprot
proteins
pubmed
15207813
uniprot
proteins
pubmed
19030102
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
2155144
uniprot
proteins
pubmed
8681381
uniprot
proteins
pubmed
9374392
uniprot
proteins
pubmed
9876175
uniprot
proteins
sequence_length
211
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted. Note=Released by platelets upon wounding.
uniprot
proteins