Ascc1
entrez
69090
canonical
uniprot
Q9D8Z1
canonical
ensembl
ENSMUSG00000044475
resolver
ensp
ENSMUSP00000052351
resolver
ensp
ENSMUSP00000126301
resolver
ensp
ENSMUSP00000161757
resolver
ensp
ENSMUSP00000161761
resolver
ensp
ENSMUSP00000161765
resolver
ensp
ENSMUSP00000336448
resolver
ensp
ENSMUSP00000336449
resolver
enst
ENSMUST00000050516
resolver
enst
ENSMUST00000164083
resolver
genesymbol
Ascc1
resolver
uniprot
Q3TAC2
resolver
uniprot_entry
ASCC1_MOUSE
resolver
uniprot_sec
Q3TAC2
resolver
amino_acid_sequence
MDVLRPQIVTFDGRNYRKNPIQEKQYQHEEDEDFYPDSMEYSDEPCGAYEVAQTPHGFRATVSAPSLLYKHIVGKRGDTKKKIEVETKTSINIPKHGHEGEIVITGQHRNGVVSARTRIDVLLDTFRRRQPFTHFLSFFLNEVEVQERFLMFQEEVLRKCSKDRGVDSTIFQNPKKLHLTIGMLVLLSEQEIQQTCEILQRCKEEFINDISGGRPLEVEMAGIEYMNDDPAMVDVLYAKVHMKDGSNRLQELVDRVLERFQSLGLIVKEWTSVKLHATVMNTLLRKDPNAEGRYNLYTADGKYIFKERESFDGRNILKTFENFYFGSLRLNSIHISQRFTVDSFGNYASCGHVDFS
uniprot
proteins
function
FUNCTION: Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction. {ECO:0000250|UniProtKB:Q8N9N2}.
uniprot
proteins
mass_dalton
41280
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26924529
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8N9N2}. Nucleus speckle {ECO:0000250|UniProtKB:Q8N9N2}. Note=Colocalizes with PRPF8 in nuclear speckles in the absence of DNA damage. {ECO:0000250|UniProtKB:Q8N9N2}.
uniprot
proteins