Tlcd2
entrez
380712
canonical
uniprot
Q8VC26
canonical
ensembl
ENSMUSG00000038217
resolver
ensp
ENSMUSP00000042958
resolver
ensp
ENSMUSP00000104074
resolver
genesymbol
Tlcd2
resolver
uniprot
Q9D837
resolver
uniprot_entry
TLCD2_MOUSE
resolver
uniprot_sec
Q9D837
resolver
amino_acid_sequence
MASWGLLVAGASFTAFRGLHWGLQLLPTPKSVRDRWMWRNIFVSLIHSLLSGVGALVGLWQFPQMVTDPINDHPPWARVLVAVSVGYFAADGVDMLWNQTLAQAWDLLCHHLAVVSCLSTAVVSGHYVGFSMVSLLLELNSICLHLRKLLLLSHKAPSLAFRVSSWASLATLVLFRLLPLGWMSLWLSRQHYQLSLALVLLCVAGLVTVGSISISTGIRILTKDILQSQPYPFILMHKETKTREPVARNTSTLSLKGSRYLYSTAAAALGGHLMVLASPKRCMTPSVLGLQERRLEPGKVAHADNASTWE
uniprot
proteins
function
FUNCTION: Regulates the composition and fluidity of the plasma membrane (By similarity). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity). Does not appear to have any effect on LCPUFA synthesis (By similarity). {ECO:0000250|UniProtKB:A6NGC4}.
uniprot
proteins
mass_dalton
34139
uniprot
proteins
protein_family
TLCD family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
310
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:A6NGC4}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 6..26; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 40..60; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 194..214; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins