Fxyd3
entrez
116831
canonical
uniprot
P59645
canonical
ensembl
ENSRNOG00000080106
resolver
ensembl
ENSRNOG00055032590
resolver
ensembl
ENSRNOG00060032585
resolver
ensembl
ENSRNOG00065033743
resolver
ensp
ENSRNOP00000104598
resolver
ensp
ENSRNOP00055046458
resolver
ensp
ENSRNOP00060046641
resolver
ensp
ENSRNOP00065047720
resolver
enst
ENSRNOT00000172857
resolver
enst
ENSRNOT00055056320
resolver
enst
ENSRNOT00060056459
resolver
enst
ENSRNOT00065057957
resolver
genesymbol
Fxyd3
resolver
uniprot_entry
FXYD3_RAT
resolver
amino_acid_sequence
MQEFALSLLVLLAGLPTLDANDPEDKDSPFYYDWHSLRVGGLICAGILCALGIIVLMSGKCKCKFSQKPSHRPGDGPPLITPGSAHNC
uniprot
proteins
function
FUNCTION: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. {ECO:0000250|UniProtKB:Q14802}.
uniprot
proteins
mass_dalton
9411
uniprot
proteins
post_translational_modification
PTM: Glutathionylated. {ECO:0000250|UniProtKB:Q14802}.
uniprot
proteins
protein_family
FXYD family
uniprot
proteins
pubmed
10950925
uniprot
proteins
sequence_length
88
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 39..59; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins