Iapp
entrez
24476
canonical
uniprot
P12969
canonical
ensembl
ENSRNOG00000082704
resolver
ensembl
ENSRNOG00055010406
resolver
ensembl
ENSRNOG00060008839
resolver
ensembl
ENSRNOG00065005720
resolver
ensp
ENSRNOP00000099257
resolver
ensp
ENSRNOP00055014172
resolver
ensp
ENSRNOP00060011462
resolver
ensp
ENSRNOP00065006029
resolver
enst
ENSRNOT00000140283
resolver
enst
ENSRNOT00055017610
resolver
enst
ENSRNOT00060014813
resolver
enst
ENSRNOT00065008547
resolver
genesymbol
Iapp
resolver
uniprot_entry
IAPP_RAT
resolver
amino_acid_sequence
MRCISRLPAVLLILSVALGHLRATPVGSGTNPQVDKRKCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYGKRNVAEDPNRESLDFLLL
uniprot
proteins
function
FUNCTION: Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis (By similarity). Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes (PubMed:35324283). Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs (PubMed:35324283). {ECO:0000250|UniProtKB:P10997, ECO:0000269|PubMed:35324283}.
uniprot
proteins
mass_dalton
10015
uniprot
proteins
protein_family
Calcitonin family
uniprot
proteins
pubmed
19360098
uniprot
proteins
pubmed
19456151
uniprot
proteins
pubmed
2223885
uniprot
proteins
pubmed
2357234
uniprot
proteins
pubmed
2654937
uniprot
proteins
pubmed
2666169
uniprot
proteins
pubmed
2668946
uniprot
proteins
pubmed
2679555
uniprot
proteins
pubmed
35324283
uniprot
proteins
sequence_length
93
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P10997}.
uniprot
proteins