Sfxn2
entrez
94279
canonical
uniprot
Q925N2
canonical
ensembl
ENSMUSG00000025036
resolver
ensp
ENSMUSP00000026011
resolver
enst
ENSMUST00000026011
resolver
genesymbol
Sfxn2
resolver
uniprot
Q3UC14
resolver
uniprot_entry
Q3UC14_MOUSE
resolver
uniprot_entry
SFXN2_MOUSE
resolver
amino_acid_sequence
MEGDLSGFNIDAPRWDQCTFLGRVKHFFNITDPRTVFASEQELDWAKAVVEKSRMGLVPPGTQMEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQVPGGMLITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMWTKRAPPLVGRWVPFAAVAAANCVNIPMMRQQELIQGICVKDRNQNELGHSQRAAAVGIAQVVISRITMAAPGMILLPVIMERLERLHLMKKVKVMHAPLQVLLCGCFLLFMVPVACGLFPQECELSVSYLEPELRDTIKAKYGEQVLFVYFNKGL
uniprot
proteins
function
FUNCTION: Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria (By similarity). Involved in mitochondrial iron homeostasis by regulating heme biosynthesis (By similarity). {ECO:0000250|UniProtKB:Q96NB2}.
uniprot
proteins
mass_dalton
36141
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
11274051
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
30570704
uniprot
proteins
sequence_length
322
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q96NB2}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q96NB2}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 99..119; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 147..167; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 223..243; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins