Prok1
entrez
192205
canonical
uniprot
Q8R414
canonical
ensembl
ENSRNOG00000079989
resolver
ensembl
ENSRNOG00055020302
resolver
ensembl
ENSRNOG00065022953
resolver
ensp
ENSRNOP00000103298
resolver
ensp
ENSRNOP00055028101
resolver
ensp
ENSRNOP00065031864
resolver
enst
ENSRNOT00000163828
resolver
enst
ENSRNOT00055034676
resolver
enst
ENSRNOT00065039228
resolver
genesymbol
Prok1
resolver
uniprot_entry
PROK1_RAT
resolver
amino_acid_sequence
MRGAVQVFIMLLLATVSDCAVITGACERDVQCGAGTCCAISLWLRGLRLCTPLGREGEECHPGSHKIPFFRKRQHHTCPCSPSLLCSRFPDGRYRCSQDLKNVNF
uniprot
proteins
function
FUNCTION: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
11643
uniprot
proteins
protein_family
AVIT (prokineticin) family
uniprot
proteins
pubmed
12054613
uniprot
proteins
sequence_length
105
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
uniprot
proteins