Epc1
entrez
13831
canonical
uniprot
Q8C9X6
canonical
ensembl
ENSMUSG00000024240
resolver
ensp
ENSMUSP00000028100
resolver
ensp
ENSMUSP00000060599
resolver
ensp
ENSMUSP00000111536
resolver
enst
ENSMUST00000050542
resolver
genesymbol
Epc1
resolver
uniprot
B2RRY2
resolver
uniprot
F8WIJ6
resolver
uniprot
Q3UEV1
resolver
uniprot
Q3UG01
resolver
uniprot
Q6PBH3
resolver
uniprot
Q7TNR8
resolver
uniprot
Q9Z299
resolver
uniprot_entry
EPC1_MOUSE
resolver
uniprot_entry
F8WIJ6_MOUSE
resolver
uniprot_entry
Q3UEV1_MOUSE
resolver
uniprot_entry
Q3UG01_MOUSE
resolver
uniprot_entry
Q6PBH3_MOUSE
resolver
uniprot_entry
Q7TNR8_MOUSE
resolver
uniprot_sec
B2RRY2
resolver
uniprot_sec
Q9Z299
resolver
amino_acid_sequence
MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFRMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPLQFEEMIDRLEKGSGQQPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGSSLIPLVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTYAIPIIPITNSSQFKHQDATDSKEFKVNKQDKADLIRPKRKYEKKPKVLPPSAAAPQQQSPAALPGFSAKDLNQYDFPSSDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKDGGLGDVRYRYCLTTLTVPQRCLGFARRRVGRGGRVVLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSEPNTSDRSSSKDLSQILVDIKSCRWRHFRPRTPSLPDSDSGELSSRKLHRSISRAGAAQPGAHTCSTSTQNRSSSGSAHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQQANSSSSAAAQQGFVSKTLDSASAQFAASALMTSEQLLGFKVKDDVVLGLGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSSLSHQVTAASSATTQVLFGNNIRLTVPSSVPTVNSVTPINARHIPRTLSAVPPSALKLAAAANCQVSKVPSSSSVDSVPRENHESEKPALNNIADNTVAMEVT
uniprot
proteins
function
FUNCTION: Component of the NuA4 histone acetyltransferase (HAT) complex, a multiprotein complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A (PubMed:28694333). The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) by promoting homologous recombination (HR) (By similarity). The NuA4 complex is also required for spermatid development by promoting acetylation of histones: histone acetylation is required for histone replacement during the transition from round to elongating spermatids (PubMed:28694333). In the NuA4 complex, EPC1 is required to recruit MBTD1 into the complex (By similarity). {ECO:0000250|UniProtKB:Q9H2F5, ECO:0000269|PubMed:28694333}.
uniprot
proteins
mass_dalton
90411
uniprot
proteins
protein_family
Enhancer of polycomb family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
28694333
uniprot
proteins
pubmed
9735366
uniprot
proteins
sequence_length
813
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:28694333}. Cytoplasm {ECO:0000269|PubMed:28694333}.
uniprot
proteins