Pcmtd1
entrez
319263
canonical
uniprot
P59913
canonical
ensembl
ENSMUSG00000051285
resolver
ensp
ENSMUSP00000059261
resolver
enst
ENSMUST00000061280
resolver
genesymbol
Pcmtd1
resolver
uniprot
Q3TGS5
resolver
uniprot_entry
PCMD1_MOUSE
resolver
uniprot_entry
Q3TGS5_MOUSE
resolver
amino_acid_sequence
MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGTPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDSKEEEEKEHIEAMKREEPPQNLLREKIMKLPLPESLKAYLTYFRDK
uniprot
proteins
function
FUNCTION: Substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Specifically binds to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but does not display methyltransferase activity. May provide an alternate maintenance pathway for modified proteins by acting as a damage-specific E3 ubiquitin ligase adaptor protein. {ECO:0000250|UniProtKB:Q96MG8}.
uniprot
proteins
mass_dalton
40693
uniprot
proteins
protein_family
L-isoaspartyl/D-aspartyl protein methyltransferase family
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
357
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P22061}. Membrane {ECO:0000250|UniProtKB:Q96MG8}; Lipid-anchor {ECO:0000250|UniProtKB:Q96MG8}.
uniprot
proteins