Cabp1
entrez
171051
canonical
uniprot
O88751
canonical
ensembl
ENSRNOG00000001173
resolver
ensp
ENSRNOP00000001551
resolver
ensp
ENSRNOP00000001552
resolver
ensp
ENSRNOP00000033685
resolver
enst
ENSRNOT00000001551
resolver
genesymbol
Cabp1
resolver
uniprot
A0A140TA91
resolver
uniprot
Q711K8
resolver
uniprot
Q91WZ7
resolver
uniprot_entry
A0A140TA91_RAT
resolver
uniprot_entry
CABP1_RAT
resolver
uniprot_sec
Q711K8
resolver
uniprot_sec
Q91WZ7
resolver
amino_acid_sequence
MSSHIAKSESKTSLLKAAAASGGSRAPRHSSARDPGLRGRRLPGPCPDSPATCGDPSSRRPLCRPVPRDEGARGSRRGLPQAHCRPRETLPPARGRDGEERGLAPALSLRGSLRSRGRGDPAPAGTPEADPFLHQLRPMLSSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR
uniprot
proteins
function
FUNCTION: Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling (By similarity). Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (PubMed:11865310). Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D. Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity). {ECO:0000250|UniProtKB:Q9JLK7, ECO:0000250|UniProtKB:Q9NZU7, ECO:0000269|PubMed:11865310}.
uniprot
proteins
mass_dalton
33017
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. The phosphorylation regulates the activity (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
11865310
uniprot
proteins
pubmed
11906216
uniprot
proteins
pubmed
12032348
uniprot
proteins
pubmed
15095872
uniprot
proteins
pubmed
18303947
uniprot
proteins
pubmed
9694893
uniprot
proteins
sequence_length
298
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15095872}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15095872}. Note=Occurs in both the cytoplasmic and cytoskeletal compartment of cell somata and dendrites.
uniprot
proteins