Sfxn3
entrez
65042
canonical
uniprot
Q9JHY2
canonical
ensembl
ENSRNOG00000015442
resolver
ensp
ENSRNOP00000021171
resolver
ensp
ENSRNOP00000083890
resolver
enst
ENSRNOT00000021171
resolver
enst
ENSRNOT00000105996
resolver
genesymbol
Sfxn3
resolver
uniprot
A0A8I5ZY86
resolver
uniprot
A0A8W1ATD7
resolver
uniprot
G3V804
resolver
uniprot_entry
A0A8I5ZY86_RAT
resolver
uniprot_entry
A0A8W1ATD7_RAT
resolver
uniprot_entry
SFXN3_RAT
resolver
uniprot_sec
G3V804
resolver
amino_acid_sequence
MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGKQLEASRNIVQNYRAGVVTPGLTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTMVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLTKHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVVSRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQKPSIDVVYYNKGL
uniprot
proteins
function
FUNCTION: Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. {ECO:0000250|UniProtKB:Q9BWM7}.
uniprot
proteins
mass_dalton
35465
uniprot
proteins
protein_family
Sideroflexin family
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
321
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:Q9BWM7}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 146..164; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 174..194; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins