Rabep2
entrez
70314
canonical
uniprot
Q91WG2
canonical
ensembl
ENSMUSG00000030727
resolver
ensp
ENSMUSP00000102015
resolver
genesymbol
Rabep2
resolver
genesymbol_syn
Rabpt5b
resolver
uniprot
Q3UMK8
resolver
uniprot
Q99KN3
resolver
uniprot_entry
RABE2_MOUSE
resolver
uniprot_sec
Q3UMK8
resolver
uniprot_sec
Q99KN3
resolver
amino_acid_sequence
MAAAPATLALDPQPQEKQKDASESSELSRLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSISSYETQIAALKQERQQQQQDFEEKDRELGHLKQLLARAHPLDSLEKQMEKAHEDSEKLREIVLPMEQEITELKGKLQRAEELIQEIQRRPRQPASLHGSTELLPLSRNPSPPLEPLEEPSGDAGPAAEAFAHNCDDSASISSFSLGGAAGSASLRGPQGLSPEQEETASLVSTGTLVPEGIFLPPPGYQLVPDSQWEQLQVEGRQLQKELESVSRERDELQEGLRRSNEDCAKQMQVLLAQVQNSEQLLRTLQGTVSQAQERVQLQMAELATSHKCLSQEVKRLNEENQGLRAEQLPSSALQGSEQREDQDEALPSSIQELHLLVQNTRQQARARQQAQEHEAERLRIEIVKLREALDEETAAKASLERQLRVQREETDVLEASLCSLRIETERVQQEQRKAQLTDLLSEQRAKTLRLQAELETSEQVQRDFVRLSQALQVRLERIRQAETLQQVRSILDEAPLRDIRDIKDS
uniprot
proteins
function
FUNCTION: Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking. By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis. {ECO:0000250|UniProtKB:Q9H5N1}.
uniprot
proteins
mass_dalton
62132
uniprot
proteins
protein_family
Rabaptin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
554
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H5N1}. Early endosome {ECO:0000250|UniProtKB:Q9H5N1}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9H5N1}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q9H5N1}.
uniprot
proteins