Kdm4d
entrez
689582
canonical
uniprot
A1A5Q5
canonical
ensembl
ENSRNOG00000045905
resolver
ensembl
ENSRNOG00055007218
resolver
ensembl
ENSRNOG00060005823
resolver
ensembl
ENSRNOG00065011690
resolver
ensp
ENSRNOP00000059913
resolver
ensp
ENSRNOP00000067344
resolver
ensp
ENSRNOP00000099256
resolver
ensp
ENSRNOP00000105224
resolver
ensp
ENSRNOP00055009496
resolver
ensp
ENSRNOP00055009500
resolver
ensp
ENSRNOP00060007251
resolver
ensp
ENSRNOP00060007257
resolver
ensp
ENSRNOP00060007261
resolver
ensp
ENSRNOP00065014534
resolver
ensp
ENSRNOP00065014536
resolver
enst
ENSRNOT00000033932
resolver
enst
ENSRNOT00000071532
resolver
enst
ENSRNOT00000124622
resolver
enst
ENSRNOT00000127250
resolver
enst
ENSRNOT00055011992
resolver
enst
ENSRNOT00055011996
resolver
enst
ENSRNOT00060009645
resolver
enst
ENSRNOT00060009652
resolver
enst
ENSRNOT00060009658
resolver
enst
ENSRNOT00065019007
resolver
enst
ENSRNOT00065019009
resolver
genesymbol
Kdm4d
resolver
genesymbol_syn
Jhdm3d
resolver
genesymbol_syn
Jmjd2d
resolver
uniprot_entry
KDM4D_RAT
resolver
amino_acid_sequence
MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKAMTVGQYRHLANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYEMWKRGQDQAVVDHTEAMGPTSQELTTWRVIQAPRKTWGLKHLRLRQVSRCLLPVATDSNIANNTQMCHTSRQAADSKGDEVQESDPAIAPPYPLGLSSPGHMSTGKRGLGRRPCELGVQESTNGAPVKRRLPEGRDDRSPSPELQSQSVTGDLIVNSDLVNPGPQHPVTASEGGLTSDP
uniprot
proteins
ec_number
1.14.11.66
uniprot
proteins
function
FUNCTION: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000250|UniProtKB:Q6B0I6}.
uniprot
proteins
mass_dalton
57188
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated via 'Lys-63'-linked ubiquitin chains. Deubiquitinated by USP14 with the help of TRIM14 leading to stabilization. {ECO:0000250|UniProtKB:Q6B0I6}.
uniprot
proteins
protein_family
JHDM3 histone demethylase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
510
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537}.
uniprot
proteins