Kif21b
entrez
16565
canonical
uniprot
Q9QXL1
canonical
ensembl
ENSMUSG00000041642
resolver
ensp
ENSMUSP00000074661
resolver
enst
ENSMUST00000075164
resolver
genesymbol
Kif21b
resolver
genesymbol_syn
Kif6
resolver
uniprot
E9PUY6
resolver
uniprot
F8VQE2
resolver
uniprot
P97424
resolver
uniprot_entry
F8VQE2_MOUSE
resolver
uniprot_entry
KI21B_MOUSE
resolver
uniprot_sec
E9PUY6
resolver
uniprot_sec
P97424
resolver
amino_acid_sequence
MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDTVTSEEEQGIIPRAIAHLFRGIDERKRRAQEKGVTGPEFKVSAQFLELYNEEILDLFDSTRDPDARHRRSNIKIHEDANGGIYTTGVTSRLINSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRVCAQPDLVNETVTGLPDGAAPTGTEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGTEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARNPYSLGASPAGPAFGGSPATSMEDASEVIRKAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQAENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEIVLRRKTQEVSALRRLAKPMSERVAGRVGLKPPNMDSGAEVSASTTSSEAESGARSVSSIVRQWNRKIDHFLGDRPTATVNGGRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKREHLQAESPEEEKGLQELAEEIEVLAANIDYINDSITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMTGSSQNHLLLDALREKAEAHPELQALIYNVQHENGYASTDEEVSEFSEGSFSQSFTMKGSTSHDDFKFKGEPKLSAQMKAVSAECLGPPLDSSTKNITKSLASLVEIKEDGVGFSIRDPYYRDKVSRTVSLPTRGSTFPRQSRGATDTSPLTRRKSYDRGQPIRSTDMGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSEVLRGIITPIGGAKGARTAPLQCISMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSSSYIKVWDIRDSAKCIRTLTSSGQVISGDACIATSTRAITSAQGEHQINQMALSPSGSMLYVASGNAVRIWELNRFQPIGKLTGHIGPVMCLTVTQTSNQHDLVVTGSKDHYVKMFQLGDCVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGFIKVWNVDNFTPIGEIKGHDSPINAICTNSKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRAPPCPDLPPPPLTLPILPFPVFPPPRSELLLHVT
uniprot
proteins
function
FUNCTION: Plus-end directed microtubule-dependent motor protein which displays processive activity (PubMed:10225949, PubMed:27117409). Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation (PubMed:27117409). Plays a role in lerning and memory (PubMed:27117409). Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface (PubMed:25172774). {ECO:0000269|PubMed:10225949, ECO:0000269|PubMed:25172774, ECO:0000269|PubMed:27117409}.
uniprot
proteins
mass_dalton
186180
uniprot
proteins
mutagenesis
MUTAGEN 96; /note="T->N: Abolishes processive activity."; /evidence="ECO:0000269|PubMed:27117409
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
10225949
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24086586
uniprot
proteins
pubmed
25172774
uniprot
proteins
pubmed
27117409
uniprot
proteins
sequence_length
1668
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10225949}. Cell projection, dendrite {ECO:0000269|PubMed:10225949, ECO:0000269|PubMed:24086586, ECO:0000269|PubMed:25172774, ECO:0000269|PubMed:27117409}. Cell projection, growth cone {ECO:0000269|PubMed:24086586}. Cell projection, axon {ECO:0000269|PubMed:10225949}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:F1M5N7}.
uniprot
proteins