ADAM28
entrez
10863
canonical
uniprot
Q9UKQ2
canonical
ensembl
ENSG00000042980
resolver
ensp
ENSP00000265769
resolver
ensp
ENSP00000393699
resolver
ensp
ENSP00000429484
resolver
ensp
ENSP00000574817
resolver
ensp
ENSP00000574818
resolver
ensp
ENSP00000620467
resolver
genesymbol
ADAM28
resolver
genesymbol_syn
ADAM23
resolver
genesymbol_syn
MDCL
resolver
hgnc
HGNC:206
resolver
uniprot
A0A384NKT9
resolver
uniprot
B2RMV5
resolver
uniprot
Q9Y339
resolver
uniprot
Q9Y3S0
resolver
uniprot_entry
A0A384NKT9_HUMAN
resolver
uniprot_entry
ADA28_HUMAN
resolver
uniprot_sec
B2RMV5
resolver
uniprot_sec
Q9Y339
resolver
uniprot_sec
Q9Y3S0
resolver
amino_acid_sequence
MLQGLLPVSLLLSVAVSAIKELPGVKKYEVVYPIRLHPLHKREAKEPEQQEQFETELKYKMTINGKIAVLYLKKNKNLLAPGYTETYYNSTGKEITTSPQIMDDCYYQGHILNEKVSDASISTCRGLRGYFSQGDQRYFIEPLSPIHRDGQEHALFKYNPDEKNYDSTCGMDGVLWAHDLQQNIALPATKLVKLKDRKVQEHEKYIEYYLVLDNGEFKRYNENQDEIRKRVFEMANYVNMLYKKLNTHVALVGMEIWTDKDKIKITPNASFTLENFSKWRGSVLSRRKRHDIAQLITATELAGTTVGLAFMSTMCSPYSVGVVQDHSDNLLRVAGTMAHEMGHNFGMFHDDYSCKCPSTICVMDKALSFYIPTDFSSCSRLSYDKFFEDKLSNCLFNAPLPTDIISTPICGNQLVEMGEDCDCGTSEECTNICCDAKTCKIKATFQCALGECCEKCQFKKAGMVCRPAKDECDLPEMCNGKSGNCPDDRFQVNGFPCHHGKGHCLMGTCPTLQEQCTELWGPGTEVADKSCYNRNEGGSKYGYCRRVDDTLIPCKANDTMCGKLFCQGGSDNLPWKGRIVTFLTCKTFDPEDTSQEIGMVANGTKCGDNKVCINAECVDIEKAYKSTNCSSKCKGHAVCDHELQCQCEEGWIPPDCDDSSVVFHFSIVVGVLFPMAVIFVVVAMVIRHQSSREKQKKDQRPLSTTGTRPHKQKRKPQMVKAVQPQEMSQMKPHVYDLPVEGNEPPASFHKDTNALPPTVFKDNPVSTPKDSNPKA
uniprot
proteins
ec_number
3.4.24.-
uniprot
proteins
function
FUNCTION: May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
uniprot
proteins
mass_dalton
87148
uniprot
proteins
post_translational_modification
PTM: Pro-domain removal and maturation may be, at least in part, autocatalytic. {ECO:0000250}.
uniprot
proteins
pubmed
10506182
uniprot
proteins
pubmed
10587367
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
21618342
uniprot
proteins
sequence_length
775
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
uniprot
proteins
transmembrane_region
TRANSMEM 666..686; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins