Bhmt
entrez
12116
canonical
uniprot
O35490
canonical
ensembl
ENSMUSG00000069324
resolver
ensembl
ENSMUSG00000074768
resolver
ensp
ENSMUSP00000096912
resolver
ensp
ENSMUSP00000135956
resolver
enst
ENSMUST00000091776
resolver
enst
ENSMUST00000099309
resolver
genesymbol
Bhmt
resolver
uniprot
Q3UEM1
resolver
uniprot
Q3UL72
resolver
uniprot
Q561N0
resolver
uniprot_entry
BHMT1_MOUSE
resolver
uniprot_sec
Q3UEM1
resolver
uniprot_sec
Q3UL72
resolver
uniprot_sec
Q561N0
resolver
amino_acid_sequence
MAPVAGKKAKKGILERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVAEKISGQKVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFEKQKFKSAQ
uniprot
proteins
ec_number
2.1.1.5
uniprot
proteins
function
FUNCTION: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. {ECO:0000250|UniProtKB:Q93088}.
uniprot
proteins
mass_dalton
45021
uniprot
proteins
pathway_participation
PATHWAY: Amine and polyamine degradation; betaine degradation; sarcosine from betaine: step 1/2.; PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (BhmT route): step 1/1. {ECO:0000250|UniProtKB:Q93088}.
uniprot
proteins
pubmed
10854776
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
407
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:O09171}. Nucleus {ECO:0000250|UniProtKB:O09171}. Note=Predominantly localized in the cytoplasm with a small fraction detected in the nucleus. Translocates into the nucleus upon oxidative stress. {ECO:0000250|UniProtKB:O09171}.
uniprot
proteins