Rab42
entrez
242681
canonical
uniprot
Q0PD08
canonical
ensembl
ENSMUSG00000089687
resolver
ensp
ENSMUSP00000047735
resolver
ensp
ENSMUSP00000222548
resolver
enst
ENSMUST00000040411
resolver
genesymbol
Rab42
resolver
genesymbol_syn
Rab43
resolver
uniprot_entry
RAB42_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. Regulated by GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity. Inhibited by GDP dissociation inhibitors (GDIs). {ECO:0000250|UniProtKB:P62820}.
uniprot
proteins
amino_acid_sequence
MEAAGCSYQFRIALLGDAGVGKTSLLRCYVAGARGAAEPDPEPTVGVEFYSRALQLPAGLRVKLQLWDTAGQECFRCITRSFYRNMVGVLLVFDVTNRESFEHIQAWHQEVVSTQGPDKVVFLLVGHKCDLNTRCVSSQEAEELAASLGMGFMETSAKSNCNVDLAFDTVTSAIEQALQQGDIKLDKDWAGVRLLHRSPNPRSSSRKQDSGTCQC
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). The physiological function of RAB42 remains undefined (Probable). {ECO:0000250|UniProtKB:P62820, ECO:0000305}.
uniprot
proteins
mass_dalton
23568
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16923123
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
215
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:P62820}; Lipid-anchor {ECO:0000250|UniProtKB:P62820}.
uniprot
proteins