Synpo
entrez
60324
canonical
uniprot
Q9Z327
canonical
ensembl
ENSRNOG00000019181
resolver
ensp
ENSRNOP00000061109
resolver
genesymbol
Synpo
resolver
uniprot_entry
SYNPO_RAT
resolver
amino_acid_sequence
MLGTHFPPPPLGPSEGRAAPCTFQIPDGSYRCLALEAEESSSEDGLQGEVRLVDLEEEGTSKSRVNHGTPPLSRAPAIIQPSSCCREARGGFQHSDKPSREWDVVQARKVMTASVSSSPVPRVAQKPALGRSTSFTEKDLKEAKERSQRIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESRGQRSPKLSQEALQTGHPSSPIGHAPGLSVNPTSPSKPGSPKHSSSQSPSRGVPGHIMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNRETQQSSPNPPETEEVPSPAADINQNPSSPNATLTTAASNSHHNQPTADVNQNPPATITPVQQNSSETQCSPNGTLDSKPNTPSADDGQRPVPAEEVRSSILLIDKVSAPPSAASPFSREATPLSSSGPPAADLMSSSLLIGMQPSTLVASAEQEVSGHAAVTTPTKVYSEVHLTLAKPASVVNRTARPFGMQSPGTTSQIEQSPMMGRRHFGEKAWAPPASSMADRSPQPQRHIMARSPMVERRLVGQRSPVVERRPLGNFTPPPTYAETLSTAPVASQVRSPPSYSTLYPSSDPKPPHLKGQVVPANKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGMEDEPFALGAEASNFQQEPIARDRSGPAAAEETVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSGHAELARCPSPTMSLPSSWKYTTNAPGGFRVASLSPARTPPASLYHGYLPENGVLRPEPTKQQPHQMRPSLYALSPVKEPAKISSRATSSRASSRTVSPRAASPAKPSSLDLVPNLPRAGLPPSPALPRPSRSSPGLYNAPVQDSLQPTAVSPTYSSDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK
uniprot
proteins
function
FUNCTION: Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity. {ECO:0000269|PubMed:11595771}.
uniprot
proteins
mass_dalton
99986
uniprot
proteins
post_translational_modification
PTM: O-glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
Synaptopodin family
uniprot
proteins
pubmed
11595771
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
9314539
uniprot
proteins
sequence_length
931
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11595771, ECO:0000269|PubMed:9314539}. Cell junction, tight junction {ECO:0000269|PubMed:9314539}. Perikaryon. Cell projection, dendritic spine {ECO:0000269|PubMed:9314539}. Postsynaptic density {ECO:0000269|PubMed:9314539}. Synapse {ECO:0000269|PubMed:9314539}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8N3V7}. Note=Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses (PubMed:9314539). {ECO:0000269|PubMed:9314539}.
uniprot
proteins