POU2AF2
entrez
341032
canonical
uniprot
Q8IXP5
canonical
ensembl
ENSG00000150750
resolver
ensp
ENSP00000280325
resolver
ensp
ENSP00000489630
resolver
enst
ENST00000280325
resolver
enst
ENST00000637637
resolver
genesymbol
POU2AF2
resolver
genesymbol_syn
C11orf53
resolver
hgnc
HGNC:30527
resolver
uniprot
A0A1C7CYV6
resolver
uniprot
A0A8V8SAS4
resolver
uniprot_entry
A0A8V8SAS4_HUMAN
resolver
uniprot_entry
OCAT1_HUMAN
resolver
uniprot_sec
A0A1C7CYV6
resolver
amino_acid_sequence
MESVPGDYSKRVYQGVRVKHTVKDLLAEKRSGQTSNSRLNGSVSSSQSPFVQMPGSPVTSGYYGVRRSFLSDSDFHNSKQFSNDVYTSSVGKPFPCESSAGQSHAALLEPYFPQEPYGDYRPPALTPNAGSLFSASPLPPLLPPPFPGDPAHFLFRDSWEQTLPDGLSQPDPVSADALLTLPPSTSCLSQLESGSIAQHRGSSWGSSLAGAQSYSLHALEDLHHTPGYPTPPPYPFTPFMTVSNDLPPKVGPLSPDEEADTGSLHDPSPWVKEDGSIAWGSYECRRAY
uniprot
proteins
function
FUNCTION: Transcriptional coactivator of POU2F3 (PubMed:35576971, PubMed:36197978). This complex drives the development of tuft cells, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues (PubMed:35576971). {ECO:0000269|PubMed:35576971, ECO:0000269|PubMed:36197978}.
uniprot
proteins
mass_dalton
31101
uniprot
proteins
mutagenesis
MUTAGEN 16; /note="V->D: Abolishes interaction with POU2F3."; /evidence="ECO:0000269|PubMed:35576971"; MUTAGEN 22; /note="V->E: Abolishes interaction with POU2F3."; /evidence="ECO:0000269|PubMed:35576971
uniprot
proteins
protein_family
POU2AF family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
25048349
uniprot
proteins
pubmed
35576971
uniprot
proteins
pubmed
36197978
uniprot
proteins
sequence_length
288
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:36197978}. Nucleus {ECO:0000269|PubMed:35576971, ECO:0000269|PubMed:36197978}. Note=Recruited to chromatin by POU2F3. {ECO:0000269|PubMed:36197978}.
uniprot
proteins