Bag4
entrez
67384
canonical
uniprot
Q8CI61
canonical
ensembl
ENSMUSG00000037316
resolver
ensp
ENSMUSP00000044725
resolver
enst
ENSMUST00000038498
resolver
genesymbol
Bag4
resolver
genesymbol_syn
Sodd
resolver
uniprot
A6H6S8
resolver
uniprot
Q3TRL9
resolver
uniprot
Q91VT5
resolver
uniprot
Q9CWG2
resolver
uniprot_entry
A6H6S8_MOUSE
resolver
uniprot_entry
BAG4_MOUSE
resolver
uniprot_sec
Q3TRL9
resolver
uniprot_sec
Q91VT5
resolver
uniprot_sec
Q9CWG2
resolver
amino_acid_sequence
MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHVPPPLYPPLRPEPPQPPVSWRGRGGAPAETTWPGEGAGGDGYYPSGGAWAEASRAGGGHQEQPPYPGYNSNYWNSVRPRAPYPGSYSVRPELQGQSLNSYANGAYGPPYPPGPGASTASYSGAYYVPGYTQSNYSTEVPNTYRSPGNSPTPMSRWMYSQQDCPTEAPPLRGQVPGYPASQNPGMTLPHYPYGDGNRAVPQSGGTGRPQDDAWASSAYGMGARYPWPSAAPSAPSAGSLYMTESASPWPGNSSPQPPPSPPPQQPKDPSYSYNPSGQGLSRHSFPCSVHQYESPGAVNNDNSDLLDSQVQYSAEPQLYGNASSEHPSNQVPSNNLPEECFSSDEGTPPSIKKIIHVLEKVQFLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL
uniprot
proteins
function
FUNCTION: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling (By similarity). Negative regulator of PRKN translocation to damaged mitochondria (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
49095
uniprot
proteins
mutagenesis
MUTAGEN 387; /note="L->P: Abolishes interaction with HSP70 and TNFRSF1A."; /evidence="ECO:0000269|PubMed:11909948"; MUTAGEN 416; /note="L->P: Abolishes interaction with HSP70 and TNFRSF1A."; /evidence="ECO:0000269|PubMed:11909948"; MUTAGEN 441; /note="A->P: Abolishes interaction with HSP70 and TNFRSF1A."; /evidence="ECO:0000269|PubMed:11909948
uniprot
proteins
pubmed
11909948
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
457
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins