Gpr135
entrez
238252
canonical
uniprot
Q7TQP2
canonical
ensembl
ENSMUSG00000043398
resolver
ensp
ENSMUSP00000058762
resolver
enst
ENSMUST00000050649
resolver
genesymbol
Gpr135
resolver
uniprot
A3KMD9
resolver
uniprot
A7E1Z8
resolver
uniprot_entry
A7E1Z8_MOUSE
resolver
uniprot_entry
GP135_MOUSE
resolver
uniprot_sec
A3KMD9
resolver
amino_acid_sequence
MEEQARPPGRPAASATLQGSAHPGGAASTATAAALSFSSVATVTLGNQSDAGRPEAAGSRGPAPLLWHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFAPPGDSGPWRSFCAASRFFSSCFGIVSTFSVALISLDRYCAIVRPPRDKLGRRRALQLLAGAWLAALGFSLPWDLLRAPREPPAPQSFHRCLYRTSPDPAQLGVAYSVGLVVACYLLPFLLMCFCRYHICKTVRLSDVRVRPMTTYARVLRFFSEVRTATTVLIMIIFVMCCWGPYCFLVLLAATRQGQATQAPSLLNVAAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNMDAFLPSQGLGFQARSRNRLRNGCANRLGACSRMPSSNPASGSGGEVVMWARKNPVVLFFREGPPDSVMEVGKLHNSETRDSSI
uniprot
proteins
function
FUNCTION: Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). {ECO:0000250|UniProtKB:Q8IZ08}.
uniprot
proteins
mass_dalton
49361
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
14623098
uniprot
proteins
sequence_length
457
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8IZ08}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000250|UniProtKB:Q8IZ08}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome (By similarity). {ECO:0000250|UniProtKB:Q8IZ08}.
uniprot
proteins
transmembrane_region
TRANSMEM 65..85; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 110..130; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 157..177; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 190..210; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 236..256; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 296..316; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 330..350; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins