Cd24
entrez
12484
canonical
uniprot
P24807
canonical
ensembl
ENSMUSG00000047139
resolver
ensp
ENSMUSP00000057983
resolver
ensp
ENSMUSP00000148921
resolver
ensp
ENSMUSP00000184690
resolver
enst
ENSMUST00000058714
resolver
enst
ENSMUST00000214476
resolver
genesymbol
Cd24
resolver
genesymbol
Cd24a
resolver
genesymbol_syn
Cd24a
resolver
genesymbol_syn
Ly-52
resolver
uniprot
A0A1L1SQ70
resolver
uniprot
P26691
resolver
uniprot
Q3THW4
resolver
uniprot
Q8CEU3
resolver
uniprot_entry
A0A1L1SQ70_MOUSE
resolver
uniprot_entry
CD24_MOUSE
resolver
uniprot_entry
Q3THW4_MOUSE
resolver
uniprot_entry
Q8CEU3_MOUSE
resolver
uniprot_sec
P26691
resolver
amino_acid_sequence
MGRAMVARLGLGLLLLALLLPTQIYCNQTSVAPFPGNQNISASPNPSNATTRGGGSSLQSTAGLLALSLSLLHLYC
uniprot
proteins
function
FUNCTION: May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses (By similarity). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90 (PubMed:19264983). Plays a role in the control of autoimmunity (PubMed:20200274). {ECO:0000250|UniProtKB:P25063, ECO:0000269|PubMed:19264983, ECO:0000269|PubMed:20200274}.
uniprot
proteins
mass_dalton
7797
uniprot
proteins
post_translational_modification
PTM: The identity of the N- and O-linked polysaccharides is not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc. {ECO:0000269|PubMed:1530634}.
uniprot
proteins
protein_family
CD24 family
uniprot
proteins
pubmed
1530634
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19264983
uniprot
proteins
pubmed
2019286
uniprot
proteins
pubmed
20200274
uniprot
proteins
pubmed
2118158
uniprot
proteins
pubmed
8226859
uniprot
proteins
sequence_length
76
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
uniprot
proteins