Syt8
entrez
60566
canonical
uniprot
Q925B4
canonical
ensembl
ENSRNOG00000020245
resolver
ensp
ENSRNOP00000108224
resolver
genesymbol
Syt8
resolver
uniprot
Q62749
resolver
uniprot
Q925B9
resolver
uniprot_entry
SYT8_RAT
resolver
uniprot_sec
Q62749
resolver
uniprot_sec
Q925B9
resolver
amino_acid_sequence
MQADRSMKMGHVSNPLSTSAPVDATAGPNLIPDLITKIPWPRWILFIAILAAGVLLVSCLLCVICYCCHRQRHRKQPKDKETVGLGSARNSTTTHLVQPDVECLEPCSGGDQPWGQLLLSLEYDFGSQEIRVGLRQAKNLKAEGTADPYARVSVSTQAGRRHETKVHRGTLCPMFEETCCFLVPPAELPKATLKVQLLDFKRFSEHEPLGELQLPLGTVDLQHVLESWYQLGPPGSTESEQMGELCFSLRYVPSSGRLTVVILEARGLNPGLAEAYVKVQLILNQRKWKKNKTSSKKGTTNPYFNEAFVFLVPVSQLQSMDLVLAVWARGLQLLAEPVGKVLLGPRASGQPLQHWADMLAHARRPIAQWHHLRSPREVDRALALQPRLPLLRPRS
uniprot
proteins
function
FUNCTION: Involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in insulin secreted cells (By similarity). {ECO:0000250|UniProtKB:Q9R0N6, ECO:0000269|PubMed:11309201}.
uniprot
proteins
mass_dalton
43980
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
11309201
uniprot
proteins
pubmed
7791877
uniprot
proteins
pubmed
9689015
uniprot
proteins
sequence_length
395
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9R0N6}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..65; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins