Nacc1
entrez
66830
canonical
uniprot
Q7TSZ8
canonical
ensembl
ENSMUSG00000001910
resolver
ensp
ENSMUSP00000001975
resolver
ensp
ENSMUSP00000315887
resolver
ensp
ENSMUSP00000315888
resolver
enst
ENSMUST00000001975
resolver
genesymbol
Nacc1
resolver
genesymbol_syn
Btbd14b
resolver
genesymbol_syn
Nac1
resolver
uniprot
Q80X97
resolver
uniprot
Q9CZ72
resolver
uniprot_entry
NACC1_MOUSE
resolver
uniprot_sec
Q80X97
resolver
uniprot_sec
Q9CZ72
resolver
amino_acid_sequence
MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSRSAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQTLGWPACSTPLPLVSRVKTEQELDSVQCTPMAKRLWDSSQKEAGGSGGNNGSRKMAKFSTPDLALNRMPQPLSMATATAAVAVVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTAEKVEALPEQVVLESRSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTCKIEPDMMSMEHSFETASHDGEAGPSAEVLQ
uniprot
proteins
function
FUNCTION: Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. Involved in the acute behavioral and neurological responses to cocaine and amphetamines. {ECO:0000269|PubMed:17130457, ECO:0000269|PubMed:17945361}.
uniprot
proteins
mass_dalton
56537
uniprot
proteins
pubmed
14521994
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17130457
uniprot
proteins
pubmed
17945361
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
514
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=Distribution in the cytoplasm is dependent on phosphorylation. {ECO:0000250}.
uniprot
proteins