Ahrr
entrez
11624
canonical
uniprot
Q3U1U7
canonical
ensembl
ENSMUSG00000021575
resolver
ensp
ENSMUSP00000022059
resolver
ensp
ENSMUSP00000105268
resolver
enst
ENSMUST00000109640
resolver
genesymbol
Ahrr
resolver
genesymbol_syn
Kiaa1234
resolver
uniprot
A0A0R4J020
resolver
uniprot
A0A0R4J1D3
resolver
uniprot
Q147Z5
resolver
uniprot
Q3U3H6
resolver
uniprot
Q69ZN4
resolver
uniprot
Q8C696
resolver
uniprot
Q9Z312
resolver
uniprot_entry
A0A0R4J1D3_MOUSE
resolver
uniprot_entry
AHRR_MOUSE
resolver
uniprot_entry
Q8C696_MOUSE
resolver
uniprot_sec
A0A0R4J020
resolver
uniprot_sec
Q147Z5
resolver
uniprot_sec
Q3U3H6
resolver
uniprot_sec
Q69ZN4
resolver
uniprot_sec
Q9Z312
resolver
amino_acid_sequence
MMIPSGECTYAGRKRRKPIQKRRLTMGAEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSPEEHSYRGFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADTDNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAPVLPSVTEMKMKSTFLKAKHRADIVVTMDSRAKAVTSLCESELHPKLNYLAGKSNGENGISLFRGQTDRSHWARALARSSCLCLRGGPDLLDPKGTSGDREEEDQKHILRRSPGAWGQREMHKYSYGLETPVHLRHLNWSTEQRSQESTTKLTRQPSKNEPSTCLVPHGSCVPYPGSQGMLSASNMASFRDSLDHPTGAYCSQMNRPLSDIHQGQVDPSTCHISQGSLGSRIPLTGMQRFTARGFSTEDAKLPSLPVTIGTPCNPVLSLDVPIKMENESGSQDIVEASTTSCLWLGTSDMARGHLVGFPARMHLKTEPDYRQQACTPHLGHGMLGTNPYSRDTVGSCREHAPLYSAHCTCLDPEPPHHFFMCSHSESQHPSLDQDCRAPIVKREPLDSPSWAAPGQVTVPRMFPKSASKTVIPSKGSDGIFLP
uniprot
proteins
function
FUNCTION: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with AHR for heterodimer formation with ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of a variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site. {ECO:0000269|PubMed:17949687, ECO:0000269|PubMed:9887096}.
uniprot
proteins
mass_dalton
77760
uniprot
proteins
pubmed
12520768
uniprot
proteins
pubmed
15368895
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17949687
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
9887096
uniprot
proteins
sequence_length
701
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:9887096}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:9887096}. Note=Predominantly in the nuclear compartment. First cytoplasmic, translocates into the nuclear compartment upon interaction with ARNT in the cytoplasmic compartment.
uniprot
proteins