Tmed9
entrez
361207
canonical
uniprot
Q5I0E7
canonical
ensembl
ENSRNOG00000021882
resolver
ensembl
ENSRNOG00055015170
resolver
ensembl
ENSRNOG00060021751
resolver
ensembl
ENSRNOG00065021846
resolver
ensp
ENSRNOP00000030668
resolver
ensp
ENSRNOP00055021161
resolver
ensp
ENSRNOP00060031130
resolver
ensp
ENSRNOP00065029973
resolver
enst
ENSRNOT00000036140
resolver
enst
ENSRNOT00055025962
resolver
enst
ENSRNOT00060037738
resolver
enst
ENSRNOT00065037165
resolver
genesymbol
Tmed9
resolver
uniprot_entry
TMED9_RAT
resolver
amino_acid_sequence
MAAVRGVRVVGTSPGLLLGRGMRAFLLLLCLAARGGALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV
uniprot
proteins
function
FUNCTION: Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
27028
uniprot
proteins
post_translational_modification
PTM: N-linked glycosylated containing high mannose. {ECO:0000250}.
uniprot
proteins
protein_family
EMP24/GP25L family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21545355
uniprot
proteins
pubmed
9472029
uniprot
proteins
sequence_length
235
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:9472029}; Single-pass type I membrane protein {ECO:0000269|PubMed:9472029}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:9472029}; Single-pass type I membrane protein {ECO:0000269|PubMed:9472029}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:9472029}; Single-pass type I membrane protein {ECO:0000269|PubMed:9472029}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Cycles between compartments of the early secretatory pathway.
uniprot
proteins
transmembrane_region
TRANSMEM 203..222; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins