L3HYPDH
entrez
112849
canonical
uniprot
Q96EM0
canonical
ensembl
ENSG00000126790
resolver
ensp
ENSP00000247194
resolver
ensp
ENSP00000702716
resolver
ensp
ENSP00000776717
resolver
enst
ENST00000247194
resolver
genesymbol
L3HYPDH
resolver
genesymbol_syn
C14orf149
resolver
hgnc
HGNC:20488
resolver
uniprot
Q96LJ5
resolver
uniprot_entry
T3HPD_HUMAN
resolver
uniprot_sec
Q96LJ5
resolver
amino_acid_sequence
MESALAVPRLPPHDPGTPVLSVVDMHTGGEPLRIVLAGCPEVSGPTLLAKRRYMRQHLDHVRRRLMFEPRGHRDMYGAVLVPSELPDAHLGVLFLHNEGYSSMCGHAVLALGRFALDFGLVPAPPAGTREARVNIHCPCGLVTAFVACEDGRSHGPVRFHSVPAFVLATDLMVDVPGHGKVMVDIAYGGAFYAFVTAEKLGLDICSAKTRDLVDAASAVTEAVKAQFKINHPDSEDLAFLYGTILTDGKDAYTKEPTTNICVFADEQVDRSPTGSGVTARIALQYHKGLLELNQMRAFKSSATGSVFTGKAVREAKCGDFKAVIVEVSGQAHYTGTASFIIEDDDPLRDGFLLK
uniprot
proteins
ec_number
4.2.1.77
uniprot
proteins
function
FUNCTION: Catalyzes the dehydration of trans-3-hydroxy-L-proline to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be required to degrade trans-3-hydroxy-L-proline from the diet and originating from the degradation of proteins such as collagen-IV that contain it. {ECO:0000269|PubMed:22528483}.
uniprot
proteins
mass_dalton
38138
uniprot
proteins
mutagenesis
MUTAGEN 273; /note="T->C: Regains racemase activity, catalyzing the conversion of trans-3-hydroxy-L-proline to cis-3-hydroxy-D-proline. Also catalyzes racemization of L-proline to D-proline, albeit at a very low level. Has lost its original dehydratase activity."; /evidence="ECO:0000269|PubMed:22528483
uniprot
proteins
protein_family
Proline racemase family
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22528483
uniprot
proteins
pubmed
24649405
uniprot
proteins
sequence_length
354
uniprot
proteins