Syt3
entrez
20981
canonical
uniprot
O35681
canonical
ensembl
ENSMUSG00000030731
resolver
ensp
ENSMUSP00000112432
resolver
ensp
ENSMUSP00000112968
resolver
ensp
ENSMUSP00000114070
resolver
ensp
ENSMUSP00000263967
resolver
ensp
ENSMUSP00000263971
resolver
ensp
ENSMUSP00000263974
resolver
ensp
ENSMUSP00000263981
resolver
ensp
ENSMUSP00000263982
resolver
ensp
ENSMUSP00000263988
resolver
ensp
ENSMUSP00000263991
resolver
ensp
ENSMUSP00000263992
resolver
ensp
ENSMUSP00000263993
resolver
enst
ENSMUST00000118831
resolver
enst
ENSMUST00000118962
resolver
enst
ENSMUST00000120262
resolver
genesymbol
Syt3
resolver
uniprot
G3X9Y1
resolver
uniprot
P97791
resolver
uniprot
Q80WV1
resolver
uniprot_entry
G3X9Y1_MOUSE
resolver
uniprot_entry
SYT3_MOUSE
resolver
uniprot_sec
P97791
resolver
uniprot_sec
Q80WV1
resolver
amino_acid_sequence
MSGDYEDDLCRRALILVSDLCARVRDADTNDRCQEFNELRIRGYPRGPDADISVSLLSVIVTFCGIVLLGVSLFVSWKLCWVPWRDKGGSAVGGGPLRKDLAPGVGLAGLVGGGGHHLGASLGGHPLLGGPHHHGHTAHHPPFAELLEPGGLGGSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLTTQADPSTEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRGGGSGEAGAPCGRISFALRYLYGSDHLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDILEGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPRKPVEHWHQLVEEKTLSSFTKGGKGLSEKENSE
uniprot
proteins
function
FUNCTION: Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes. {ECO:0000250|UniProtKB:P40748, ECO:0000250|UniProtKB:Q9BQG1}.
uniprot
proteins
mass_dalton
63254
uniprot
proteins
mutagenesis
MUTAGEN 10; /note="C->A: Abolishes disulfide-dependent homodimerization. Abolishes disulfide-dependent homodimerization; when associated with A-21."; /evidence="ECO:0000269|PubMed:10531343"; MUTAGEN 21; /note="C->A: Abolishes disulfide-dependent homodimerization; when associated with A-10. Does not affect disulfide-dependent homodimerization; when associated with A-33."; /evidence="ECO:0000269|PubMed:10531343"; MUTAGEN 33; /note="C->A: Does not affect disulfide-dependent homodimerization; when associated with A-21."; /evidence="ECO:0000269|PubMed:10531343
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
10531343
uniprot
proteins
pubmed
10531344
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
587
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P40748}; Single-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 55..75; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins