Plbd1
entrez
297694
canonical
uniprot
Q5U2V4
canonical
ensembl
ENSRNOG00000008933
resolver
ensembl
ENSRNOG00055025657
resolver
ensembl
ENSRNOG00060008496
resolver
ensembl
ENSRNOG00065011774
resolver
ensp
ENSRNOP00000011930
resolver
ensp
ENSRNOP00055036204
resolver
ensp
ENSRNOP00060010867
resolver
ensp
ENSRNOP00065014637
resolver
enst
ENSRNOT00000011930
resolver
enst
ENSRNOT00055044249
resolver
enst
ENSRNOT00060014169
resolver
enst
ENSRNOT00065019131
resolver
genesymbol
Plbd1
resolver
uniprot_entry
LYLAP_RAT
resolver
amino_acid_sequence
MCHRSHGRSLRPPSPLLLLLPLLLQSPWAAGAAEKHNSAGVHYATAYWLPDTKAVEIKMVLDKKGDAYGFYNDSIQTTGWGVLEIKAGYGSQILSNEIIMFLAGYLEGYLTALHMYDHFTNLYPQLIKNPSIVKKVQDFMEKQELWTRKNIKDQKDDPFWRHTGYVVSQLDGMYLGAQKRASEEEMKPMTMFQIQFLNAVGDLLDLIPSLSPTKSSSLKKFKIWEMGHCSALIKVLPGFENIYFAHSSWYTYAAMLRIYKHWDFNIKDKYTASNRLSFSSYPGFLESLDDFYILSSGLILLQTTNSVYNKTLLKLVVPESLLAWQRVRVANMMAQGGKEWSQLFSMYNSGTYNNQYMVLDLKKVTLKKSIDRGALYVVEQIPTYVEYSDQTNILRKGYWASYNIPFHKTVYNWSGYPLLVHKLGLDYSYDLAPRAKIFRRDQGTVTDMASMKHIMRYNNYKVDPYSKGDPCSTICCREDLNEASPSPGGCYDTKVADIFLASQYKAYAISGPTVQNGLPPFNWNRFNDTLHQGMPDVFDFDFVTMKPILT
uniprot
proteins
ec_number
3.4.11.-
uniprot
proteins
function
FUNCTION: Lysosomal processive monoaminopeptidase that preferentially cleaves hydrophobic amino acids, with strong preference for leucine residues. Plays a key role in the degradation of hydrophobic transmembrane domains within the lysosome. {ECO:0000250|UniProtKB:Q6P4A8}.
uniprot
proteins
mass_dalton
63027
uniprot
proteins
post_translational_modification
PTM: Proteolytically activated within lysosomes. Undergoes autocatalytic cleavage into an N-terminal A chain and a C-terminal B chain. Both chains A and B remain associated in the mature protein. An additional maturation step involves the removal of a segment spanning residues Leu-210-228-Cys, which occludes the active site. {ECO:0000250|UniProtKB:Q6P4A8}.
uniprot
proteins
protein_family
Ntn-hydrolase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
550
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000250|UniProtKB:Q9GL30}.
uniprot
proteins