Plgrkt
entrez
67759
canonical
uniprot
Q9D3P8
canonical
ensembl
ENSMUSG00000016495
resolver
ensp
ENSMUSP00000016639
resolver
ensp
ENSMUSP00000120466
resolver
ensp
ENSMUSP00000314986
resolver
ensp
ENSMUSP00000349073
resolver
enst
ENSMUST00000016639
resolver
enst
ENSMUST00000143467
resolver
genesymbol
Plgrkt
resolver
uniprot
Q3TCJ3
resolver
uniprot_entry
PLRKT_MOUSE
resolver
uniprot_sec
Q3TCJ3
resolver
amino_acid_sequence
MGFIFSKSMNENMKNQQEFMVTHARLQLERHLTMQNEMRERQMAMQIAWSREFLKYFGTFFGIATISLATGALKRKKPAFLVPIVPLSFIFTYQYDLGYGTLLQRMKSEAEDILETEKTKLELPKGLITFESLEKARREQSKLFSDK
uniprot
proteins
function
FUNCTION: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9. {ECO:0000269|PubMed:19897580, ECO:0000269|PubMed:21795689, ECO:0000269|PubMed:21940822}.
uniprot
proteins
mass_dalton
17261
uniprot
proteins
mutagenesis
MUTAGEN 147; /note="K->A: Disrupts binding to plasminogen."; /evidence="ECO:0000269|PubMed:19897580
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19897580
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21795689
uniprot
proteins
pubmed
21940822
uniprot
proteins
sequence_length
147
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19897580, ECO:0000269|PubMed:21795689}; Multi-pass membrane protein {ECO:0000269|PubMed:19897580, ECO:0000269|PubMed:21795689}. Note=Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/Plaur.
uniprot
proteins
transmembrane_region
TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 79..99; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins