MRC1
entrez
4360
canonical
uniprot
P22897
canonical
ensembl
ENSG00000260314
resolver
ensp
ENSP00000455897
resolver
genesymbol
MRC1
resolver
genesymbol_syn
CLEC13D
resolver
genesymbol_syn
CLEC13DL
resolver
genesymbol_syn
MRC1L1
resolver
hgnc
HGNC:7228
resolver
uniprot
A5PKW3
resolver
uniprot
Q5VSJ2
resolver
uniprot
Q5VSK2
resolver
uniprot_entry
MRC1_HUMAN
resolver
uniprot_sec
A5PKW3
resolver
uniprot_sec
Q5VSJ2
resolver
uniprot_sec
Q5VSK2
resolver
amino_acid_sequence
MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHCNESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNWNTGDPSGERNDCVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLTTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSPGTSDMKDLVGNIEQNEHSVI
uniprot
proteins
function
FUNCTION: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; FUNCTION: (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens.; FUNCTION: (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. {ECO:0000269|PubMed:18266465}.; FUNCTION: (Microbial infection) Interacts with Hepatitis B virus envelope protein. {ECO:0000269|PubMed:19683778}.
uniprot
proteins
mass_dalton
166012
uniprot
proteins
pubmed
10779515
uniprot
proteins
pubmed
1294118
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1730714
uniprot
proteins
pubmed
18266465
uniprot
proteins
pubmed
18780401
uniprot
proteins
pubmed
19683778
uniprot
proteins
pubmed
20035344
uniprot
proteins
pubmed
2258707
uniprot
proteins
pubmed
2373685
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
1456
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}. Cell membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}.
uniprot
proteins
transmembrane_region
TRANSMEM 1390..1410; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins