Tdrd3
entrez
306066
canonical
uniprot
Q66HC1
canonical
ensembl
ENSRNOG00000009034
resolver
ensp
ENSRNOP00000083043
resolver
ensp
ENSRNOP00000086500
resolver
ensp
ENSRNOP00000104599
resolver
enst
ENSRNOT00000119103
resolver
enst
ENSRNOT00000157501
resolver
genesymbol
Tdrd3
resolver
uniprot
A0A8I6A6B7
resolver
uniprot
A0ABK0LLX3
resolver
uniprot_entry
A0A8I6A6B7_RAT
resolver
uniprot_entry
A0ABK0LLX3_RAT
resolver
uniprot_entry
TDRD3_RAT
resolver
amino_acid_sequence
MLRVQMTDGHTSCTAVEFSYISKISLNTPPGTKVKLSGTVDIKNGFLLLSDSNTTVLGGEVEHLIDKWALQRSLLKHNRSNIGAEGGPPPFLPFGQKCASTVQVDSRELDRRKTLQVSLPAKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGVRSHLNIGAGGHRNREVSQKEKASKSESKNEGVYRELVDEKALKHITEMGFSKEASRQALMDNANNLEAALNVLLNSSKQKPVVGPPPRGRGKGRGRVRSEDEEDLGNARPSAPSTLFDFLESKMGTLNMEEPRSQPQHLYQGQHRVSNTEQNGIKDGNQSRHLPRNDPRQPRNEKPPRFQRDTPNLKSALENSVLSRNRGSERPSSSSGSDVWAEERIKCDRPYSRYDRTKDASYPLGFQHNDGAFKRRDNSMQNRSGRGPLYAEAKENPHPSEFVDYNNQKRGKRENQTSNPDHFYDRKSRTMNSEAFSGLKIEKHFSANTDYQNPVQSNSFVGVPNGETDMPMKGRRVGPIKPAGPVTAVPYDDKIFYNSGPKRRSGPIKPEKVIESSIPVEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFTDYGNYEEVLLSNIKPVQTEAWEEEGTYDHTIEFRRGGDGQPRRSTRPTQQFYQPPRARN
uniprot
proteins
function
FUNCTION: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. {ECO:0000250|UniProtKB:Q9H7E2}.
uniprot
proteins
mass_dalton
73028
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
651
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H7E2}. Nucleus {ECO:0000250|UniProtKB:Q9H7E2}. Note=Predominantly cytoplasmic. Associated with actively translating polyribosomes. Component of stress granules. {ECO:0000250|UniProtKB:Q9H7E2}.
uniprot
proteins