POU2F2
entrez
5452
canonical
uniprot
P09086
canonical
ensembl
ENSG00000028277
resolver
ensp
ENSP00000339369
resolver
ensp
ENSP00000373992
resolver
ensp
ENSP00000431603
resolver
ensp
ENSP00000436988
resolver
ensp
ENSP00000437224
resolver
ensp
ENSP00000452930
resolver
ensp
ENSP00000453255
resolver
ensp
ENSP00000509972
resolver
ensp
ENSP00000602837
resolver
enst
ENST00000342301
resolver
enst
ENST00000560398
resolver
enst
ENST00000692977
resolver
genesymbol
POU2F2
resolver
genesymbol_syn
OCT2
resolver
genesymbol_syn
OTF2
resolver
hgnc
HGNC:9213
resolver
uniprot
A0A8I5KYI8
resolver
uniprot
B5ME60
resolver
uniprot
H0YLL6
resolver
uniprot
Q16648
resolver
uniprot
Q7M4M8
resolver
uniprot
Q9BRS4
resolver
uniprot_entry
A0A8I5KYI8_HUMAN
resolver
uniprot_entry
B5ME60_HUMAN
resolver
uniprot_entry
H0YLL6_HUMAN
resolver
uniprot_entry
PO2F2_HUMAN
resolver
uniprot_sec
Q16648
resolver
uniprot_sec
Q7M4M8
resolver
uniprot_sec
Q9BRS4
resolver
activity_regulation
ACTIVITY REGULATION: Transactivation activity is enhanced by transcriptional coactivator POU2AF1. {ECO:0000250|UniProtKB:Q00196}.
uniprot
proteins
amino_acid_sequence
MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPSTKIKAEDPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP
uniprot
proteins
function
FUNCTION: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654). Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874). {ECO:0000250|UniProtKB:Q00196, ECO:0000269|PubMed:10480874, ECO:0000269|PubMed:2328728, ECO:0000269|PubMed:2901913, ECO:0000269|PubMed:2904654, ECO:0000269|PubMed:7859290}.; FUNCTION: [Isoform 5]: Activates the U2 small nuclear RNA (snRNA) promoter. {ECO:0000269|PubMed:1739980}.
uniprot
proteins
mass_dalton
51209
uniprot
proteins
mutagenesis
MUTAGEN 340..342; /note="VIR->FNP: Suppresses DNA-binding ability.
uniprot
proteins
protein_family
Class-2 subfamily
uniprot
proteins
protein_family
POU transcription factor family
uniprot
proteins
pubmed
10480874
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1739980
uniprot
proteins
pubmed
2328728
uniprot
proteins
pubmed
2901913
uniprot
proteins
pubmed
2904653
uniprot
proteins
pubmed
2904654
uniprot
proteins
pubmed
3072196
uniprot
proteins
pubmed
3265124
uniprot
proteins
pubmed
7859290
uniprot
proteins
pubmed
7888080
uniprot
proteins
pubmed
7914745
uniprot
proteins
sequence_length
479
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus.
uniprot
proteins