Dnajc9
entrez
108671
canonical
uniprot
Q91WN1
canonical
ensembl
ENSMUSG00000021811
resolver
ensp
ENSMUSP00000022345
resolver
enst
ENSMUST00000022345
resolver
genesymbol
Dnajc9
resolver
uniprot
Q3TSG3
resolver
uniprot
Q8R0E3
resolver
uniprot_entry
DNJC9_MOUSE
resolver
uniprot_sec
Q3TSG3
resolver
uniprot_sec
Q8R0E3
resolver
amino_acid_sequence
MGLLELCEQVFGTADLYQVLGVRREASDGEVRRGYHKVSLQVHPDRVEEDQKEDATRRFQILGRVYAVLSDKEQKAVYDEQGTVDEDSAGLNQDRDWDAYWRLLFKKISLEDIQAFEKTYKGSEEELNDIKQAYLDFKGDMDQIMESVLCVQYTDEPRIRNIIQKAIESKEIPAYSAFVKESKQKMNARKRRAQEEAKEAELSRKELGLEEGVDNLKALIQSRQKDRQKEMDSFLAQMEAKYCKPSKGGKRTALKKEKK
uniprot
proteins
function
FUNCTION: Acts as a dual histone chaperone and heat shock co-chaperone (By similarity). As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers; and may thereby assist MCM2 in histone H3-H4 heterodimer recognition and facilitate the assembly of histones into nucleosomes (By similarity). May also act as a histone co-chaperone together with TONSL (By similarity). May recruit histone chaperones ASF1A, NASP and SPT2 to histone H3-H4 heterodimers (By similarity). Also plays a role as co-chaperone of the HSP70 family of molecular chaperone proteins, such as HSPA1A, HSPA1B and HSPA8 (By similarity). As a co-chaperone, may play a role in the recruitment of HSP70-type molecular chaperone machinery to histone H3-H4 substrates, thereby maintaining the histone structural integrity (By similarity). Exhibits activity to assemble histones onto DNA in vitro (By similarity). {ECO:0000250|UniProtKB:Q8WXX5}.
uniprot
proteins
mass_dalton
30059
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
259
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8WXX5}. Cytoplasm {ECO:0000250|UniProtKB:Q8WXX5}. Cell membrane {ECO:0000250|UniProtKB:Q8WXX5}. Note=Predominantly nuclear. Translocates to the cytoplasm and membrane after heat shock. {ECO:0000250|UniProtKB:Q8WXX5}.
uniprot
proteins