TXNDC2
entrez
84203
canonical
uniprot
Q86VQ3
canonical
ensembl
ENSG00000168454
resolver
ensp
ENSP00000304908
resolver
ensp
ENSP00000350419
resolver
genesymbol
TXNDC2
resolver
genesymbol_syn
SPTRX
resolver
genesymbol_syn
SPTRX1
resolver
hgnc
HGNC:16470
resolver
uniprot
A0A140VJY8
resolver
uniprot
A5YM73
resolver
uniprot
Q8N7U4
resolver
uniprot
Q96RX3
resolver
uniprot
Q9H0L8
resolver
uniprot_entry
A0A140VJY8_HUMAN
resolver
uniprot_entry
TXND2_HUMAN
resolver
uniprot_sec
A5YM73
resolver
uniprot_sec
Q8N7U4
resolver
uniprot_sec
Q96RX3
resolver
uniprot_sec
Q9H0L8
resolver
amino_acid_sequence
MDVDKELGMESVKAGASGKPEMRLGTQEETSEGDANESSLLVLSSNVPLLALEFLEIAQAKEKAFLPMVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADNCEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAELK
uniprot
proteins
function
FUNCTION: Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
uniprot
proteins
mass_dalton
60404
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
11399755
uniprot
proteins
pubmed
12387870
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16177791
uniprot
proteins
sequence_length
553
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11399755}. Note=In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
uniprot
proteins