P2ry12
entrez
70839
canonical
uniprot
Q9CPV9
canonical
ensembl
ENSMUSG00000036353
resolver
ensp
ENSMUSP00000051353
resolver
ensp
ENSMUSP00000126819
resolver
ensp
ENSMUSP00000143036
resolver
ensp
ENSMUSP00000143521
resolver
ensp
ENSMUSP00000191238
resolver
enst
ENSMUST00000050360
resolver
enst
ENSMUST00000170388
resolver
enst
ENSMUST00000196583
resolver
enst
ENSMUST00000199609
resolver
genesymbol
P2ry12
resolver
uniprot
Q546L4
resolver
uniprot_entry
P2Y12_MOUSE
resolver
uniprot_entry
Q546L4_MOUSE
resolver
amino_acid_sequence
MDVPGVNTTSANTTFSPGTSTLCVRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGPLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVVIWAFMFLISLPNMILTNRRPKDKDVTKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKVPKKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCSAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLTSMLRCSNSTSTSGTNKKKGQEGGEPSEETPM
uniprot
proteins
function
FUNCTION: Receptor for ADP and ATP coupled to G proteins that inhibit the adenylyl cyclase second messenger system. Required for normal platelet aggregation and blood coagulation. {ECO:0000269|PubMed:12897207}.
uniprot
proteins
mass_dalton
39474
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12897207
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
347
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 34..56; /note="Helical; Name=1"; /evidence="ECO:0000250"; TRANSMEM 68..88; /note="Helical; Name=2"; /evidence="ECO:0000250"; TRANSMEM 104..124; /note="Helical; Name=3"; /evidence="ECO:0000250"; TRANSMEM 149..168; /note="Helical; Name=4"; /evidence="ECO:0000250"; TRANSMEM 192..213; /note="Helical; Name=5"; /evidence="ECO:0000250"; TRANSMEM 240..265; /note="Helical; Name=6"; /evidence="ECO:0000250"; TRANSMEM 285..304; /note="Helical; Name=7"; /evidence="ECO:0000250
uniprot
proteins