Gins4
entrez
290842
canonical
uniprot
Q499W2
canonical
ensembl
ENSRNOG00000018040
resolver
ensembl
ENSRNOG00055008424
resolver
ensembl
ENSRNOG00065008932
resolver
ensp
ENSRNOP00000024301
resolver
ensp
ENSRNOP00055011444
resolver
ensp
ENSRNOP00065010693
resolver
enst
ENSRNOT00055014253
resolver
enst
ENSRNOT00065014280
resolver
genesymbol
Gins4
resolver
genesymbol_syn
Sld5
resolver
uniprot_entry
SLD5_RAT
resolver
amino_acid_sequence
MTEVQDLHGQDSDEGSEEVVLTPAELIERLEQAWMNEKFAPELLESKSEIVECVMEQLEHMEENLRRAKKGDLKVSIHRMEMERIRYVLSSYLRCRLMKIEKFFPHILEKEKTRPAGEPSSLSPEEFVFAKEYMDHTETHFKNVALKHMPPNLQKVDLMRAVPKPDLDSYVFLRVKERQENILVEPEADEQRDYVIDLEEGSQHLIRYKTIAPLVASGAVQLI
uniprot
proteins
function
FUNCTION: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. {ECO:0000250|UniProtKB:O75419}.
uniprot
proteins
mass_dalton
26062
uniprot
proteins
protein_family
GINS4/SLD5 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
223
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O75419}. Chromosome {ECO:0000250|UniProtKB:O75419}. Note=Associates with chromatin. {ECO:0000250|UniProtKB:O75419}.
uniprot
proteins