Ntrk3
entrez
29613
canonical
uniprot
Q03351
canonical
ensembl
ENSRNOG00000018674
resolver
ensembl
ENSRNOG00055008845
resolver
ensembl
ENSRNOG00060003667
resolver
ensembl
ENSRNOG00065029604
resolver
ensp
ENSRNOP00000044402
resolver
ensp
ENSRNOP00000046059
resolver
ensp
ENSRNOP00000049463
resolver
genesymbol
Ntrk3
resolver
genesymbol_syn
Trkc
resolver
uniprot
Q68G04
resolver
uniprot_entry
NTRK3_RAT
resolver
uniprot_entry
Q68G04_RAT
resolver
amino_acid_sequence
MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRGLHTLNAVDMELYTGLQKLTIKNSGLRNIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELRLEQNFFNCSCDIRWMQLWQEQGEARLDSQSLYCISADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLVEPEVRLEHCIEFVVRGNPTPTLHWLYNGQPLRESKIIHMDYYQEGEVSEGCLLFNKPTHYNNGNYTLIAKNALGTANQTINGHFLKEPFPESTDFFDFESDASPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFIMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRLAASAASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG
uniprot
proteins
ec_number
2.7.10.1
uniprot
proteins
function
FUNCTION: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (By similarity). NTRK3 isoforms containing insertions within the kinase domain can autophosphorylate in response to NTF3/neurotrophin-3, but cannot mediate downstream phenotypic responses (PubMed:8494647, PubMed:8494648). {ECO:0000250|UniProtKB:Q16288, ECO:0000269|PubMed:8494647, ECO:0000269|PubMed:8494648}.
uniprot
proteins
mass_dalton
97064
uniprot
proteins
post_translational_modification
PTM: Ligand-mediated auto-phosphorylation.
uniprot
proteins
protein_family
Insulin receptor subfamily
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Tyr protein kinase family
uniprot
proteins
pubmed
12471037
uniprot
proteins
pubmed
1488112
uniprot
proteins
pubmed
15167895
uniprot
proteins
pubmed
17967490
uniprot
proteins
pubmed
21775604
uniprot
proteins
pubmed
8494647
uniprot
proteins
pubmed
8494648
uniprot
proteins
pubmed
9856458
uniprot
proteins
sequence_length
864
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 430..453; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins