Cert1
entrez
68018
canonical
uniprot
Q9EQG9
canonical
ensembl
ENSMUSG00000021669
resolver
ensp
ENSMUSP00000076856
resolver
ensp
ENSMUSP00000105070
resolver
genesymbol
Cert1
resolver
genesymbol_syn
Cert
resolver
genesymbol_syn
Col4a3bp
resolver
genesymbol_syn
Stard11
resolver
uniprot
Q3TQF6
resolver
uniprot
Q8BNN8
resolver
uniprot
Q8C8H3
resolver
uniprot
Q8CAR3
resolver
uniprot
Q91WB1
resolver
uniprot
Q9CU52
resolver
uniprot
Q9EQG8
resolver
uniprot_entry
CERT_MOUSE
resolver
uniprot_sec
Q3TQF6
resolver
uniprot_sec
Q8BNN8
resolver
uniprot_sec
Q8C8H3
resolver
uniprot_sec
Q8CAR3
resolver
uniprot_sec
Q91WB1
resolver
uniprot_sec
Q9CU52
resolver
uniprot_sec
Q9EQG8
resolver
amino_acid_sequence
MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNTLSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPEHRQQWVDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDVCADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHNTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREESWQKRHDREVEKRRRVEEAYKNVMEELKKKPRFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDTFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMNYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIVYQTHKRVWPASQRDVLYLSAIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINIAMICQTLVSPPEGDQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
uniprot
proteins
function
FUNCTION: Shelters ceramides inside its steroidogenic acute regulatory lipid transfer (START) domain and mediates their intracellular trafficking in a non-vesicular manner from the endoplasmic reticulum to the Golgi apparatus for conversion to sphingomyelin. Efficiently transfers ceramide molecules having long-chain fatty chains, but not those with very long acyl chains. Capable of transferring diacylglycerol, although with very low efficiency. {ECO:0000250|UniProtKB:Q9Y5P4}.
uniprot
proteins
mass_dalton
71111
uniprot
proteins
post_translational_modification
PTM: Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity. Inactivated by hyperphosphorylation of serine residues by CSNK1G2/CK1 that triggers dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. {ECO:0000250|UniProtKB:Q9Y5P4}.
uniprot
proteins
pubmed
11007769
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
624
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Y5P4}. Golgi apparatus {ECO:0000250|UniProtKB:Q9Y5P4}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9Y5P4}. Note=Preferentially localized to the Golgi apparatus. {ECO:0000250|UniProtKB:Q9Y5P4}.
uniprot
proteins