Sdhaf3
entrez
362323
canonical
uniprot
Q6TUF2
canonical
ensembl
ENSRNOG00000011283
resolver
ensembl
ENSRNOG00055001833
resolver
ensembl
ENSRNOG00060020515
resolver
ensembl
ENSRNOG00065010756
resolver
ensp
ENSRNOP00000015286
resolver
genesymbol
Sdhaf3
resolver
genesymbol_syn
Acn9
resolver
uniprot_entry
SDHF3_RAT
resolver
amino_acid_sequence
MTGRHVSRVRSLYRRILQLHRALPPDLKALGDQYVKDEFRRHKTVGPGEAQRFLKEWETYAAVLWQQAKDSRQSSSGKACFGTSLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSITESTKPHL
uniprot
proteins
function
FUNCTION: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit Sdhb of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. {ECO:0000250|UniProtKB:Q04401, ECO:0000250|UniProtKB:Q8SZ16}.
uniprot
proteins
mass_dalton
14525
uniprot
proteins
protein_family
Complex I LYR family
uniprot
proteins
protein_family
SDHAF3 subfamily
uniprot
proteins
pubmed
15057822
uniprot
proteins
sequence_length
125
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q04401}.
uniprot
proteins