Spcs1
entrez
69019
canonical
uniprot
Q9D958
canonical
ensembl
ENSMUSG00000021917
resolver
ensp
ENSMUSP00000139654
resolver
ensp
ENSMUSP00000154282
resolver
ensp
ENSMUSP00000154732
resolver
enst
ENSMUST00000186131
resolver
enst
ENSMUST00000226782
resolver
enst
ENSMUST00000228736
resolver
genesymbol
Spcs1
resolver
genesymbol_syn
Spc12
resolver
uniprot
A0A2I3BRW0
resolver
uniprot
Q8BJM2
resolver
uniprot_entry
A0A2I3BRW0_MOUSE
resolver
uniprot_entry
SPCS1_MOUSE
resolver
uniprot_sec
Q8BJM2
resolver
amino_acid_sequence
MARGGARGCPCPSETSASGATAEVKRSAGRPCSRYRPPQTLLLNNRLRPFRCRYRSSATMLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYVAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDLGTEDKKSGDRKIKRHAKNN
uniprot
proteins
function
FUNCTION: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Dispensable for SPC enzymatic activity (By similarity). {ECO:0000250|UniProtKB:P46965, ECO:0000250|UniProtKB:Q9Y6A9}.
uniprot
proteins
mass_dalton
18186
uniprot
proteins
post_translational_modification
PTM: May be phosphorylated. {ECO:0000250|UniProtKB:Q9Y6A9}.
uniprot
proteins
protein_family
SPCS1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
161
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P83362}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P83362}.
uniprot
proteins
transmembrane_region
TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 108..128; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins