Klrb1c
entrez
17059
canonical
uniprot
P27814
canonical
ensembl
ENSMUSG00000030325
resolver
ensp
ENSMUSP00000127297
resolver
ensp
ENSMUSP00000134504
resolver
enst
ENSMUST00000167691
resolver
enst
ENSMUST00000174404
resolver
genesymbol
Klrb1c
resolver
genesymbol_syn
Ly55c
resolver
genesymbol_syn
Nkrp1c
resolver
uniprot
A0A1U9W192
resolver
uniprot
A0A1U9W195
resolver
uniprot
E9Q3U6
resolver
uniprot
G3UZI0
resolver
uniprot
Q541U5
resolver
uniprot
Q925G3
resolver
uniprot_entry
A0A1U9W192_MOUSE
resolver
uniprot_entry
A0A1U9W195_MOUSE
resolver
uniprot_entry
E9Q3U6_MOUSE
resolver
uniprot_entry
G3UZI0_MOUSE
resolver
uniprot_entry
KLRBC_MOUSE
resolver
uniprot_sec
Q541U5
resolver
uniprot_sec
Q925G3
resolver
amino_acid_sequence
MDTASIYLGLKPPRTLGAWHESPPSLPPDACRCPRSHRLALKLSCAGLILLVLTLIGMSVLVRVLVQKPSREKCCVFIQENLNKTTDCSVNLECPQDWLLHRDKCFHVSQVSNTWEEGQADCGRKGATLLLIQDQEELRFLLDSIKEKYNSFWIGLRFTLPDMNWKWINGTTFNSDVLKITGVTENGSCASILGDKVTPESCASDNRWICQKELNHETPSNDS
uniprot
proteins
function
FUNCTION: Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. {ECO:0000269|PubMed:12813047, ECO:0000269|PubMed:15814704}.
uniprot
proteins
mass_dalton
25077
uniprot
proteins
mutagenesis
MUTAGEN 7; /note="Y->F: Decreased Ca(2+) mobilization."; /evidence="ECO:0000269|PubMed:15814704"; MUTAGEN 31; /note="C->S: Absence of Ca(2+) mobilization and no LCK association."; /evidence="ECO:0000269|PubMed:15814704
uniprot
proteins
pubmed
10229823
uniprot
proteins
pubmed
11685472
uniprot
proteins
pubmed
12813047
uniprot
proteins
pubmed
1506685
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15814704
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16751398
uniprot
proteins
pubmed
1880421
uniprot
proteins
sequence_length
223
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 46..66; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins