Arf5
entrez
79117
canonical
uniprot
P84083
canonical
genesymbol
Arf5
resolver
uniprot
P26437
resolver
uniprot_entry
ARF5_RAT
resolver
uniprot_sec
P26437
resolver
amino_acid_sequence
MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
uniprot
proteins
function
FUNCTION: GTP-binding protein involved in protein trafficking. Contributes to vesicle budding and uncoating at the Golgi apparatus. Regulates mTORC1 activity at the plasma membrane by promoting its recruitment to membrane ruffles, facilitating activation via the PI3K/Akt signaling pathway. Acts as an early responder to lysosomal damage and participates in lysosomal quality control pathways. {ECO:0000250|UniProtKB:P84085}.
uniprot
proteins
mass_dalton
20530
uniprot
proteins
protein_family
Arf family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
10022920
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8813705
uniprot
proteins
sequence_length
180
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P84085}. Golgi apparatus {ECO:0000250|UniProtKB:P84085}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P84085}. Lysosome membrane {ECO:0000250|UniProtKB:P84085}; Lipid-anchor {ECO:0000250|UniProtKB:P84085}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:P84085}; Lipid-anchor {ECO:0000250|UniProtKB:P84084}.
uniprot
proteins