Sit1
entrez
500449
canonical
uniprot
Q5M869
canonical
ensembl
ENSRNOG00000021546
resolver
ensembl
ENSRNOG00055016901
resolver
ensembl
ENSRNOG00060003793
resolver
ensembl
ENSRNOG00065009741
resolver
ensp
ENSRNOP00000036171
resolver
ensp
ENSRNOP00055023118
resolver
ensp
ENSRNOP00060004754
resolver
ensp
ENSRNOP00065011819
resolver
enst
ENSRNOT00000035040
resolver
enst
ENSRNOT00055028703
resolver
enst
ENSRNOT00060006352
resolver
enst
ENSRNOT00065015650
resolver
genesymbol
Sit1
resolver
genesymbol_syn
Sit
resolver
uniprot_entry
SIT1_RAT
resolver
amino_acid_sequence
MSRENNCTTADLAWGIPSITQAWGLWALFGVVTMLLLISLAALLSQWTRGRRRTQEEQGPPSGRSVEEVPLYGNLHYLQTGRLSEESRSEEQDPSSGGLARGAEEATCYTSLQLRPAQGRIPSSGTPIKYCEVVLDSEPKPQASGPEPELYASVCAQTRRARASFPDQAYANSQPAPS
uniprot
proteins
function
FUNCTION: Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.
uniprot
proteins
mass_dalton
19368
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosines upon TCR activation; which promotes recruitment of PTPN11, GRB2 and CSK. {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16160011
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
178
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 24..44; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins