TMEM177
entrez
80775
canonical
uniprot
Q53S58
canonical
ensembl
ENSG00000144120
resolver
ensp
ENSP00000272521
resolver
ensp
ENSP00000385966
resolver
ensp
ENSP00000402661
resolver
ensp
ENSP00000537166
resolver
ensp
ENSP00000537167
resolver
ensp
ENSP00000537168
resolver
ensp
ENSP00000537169
resolver
ensp
ENSP00000537170
resolver
ensp
ENSP00000591730
resolver
ensp
ENSP00000591731
resolver
ensp
ENSP00000591732
resolver
ensp
ENSP00000591733
resolver
ensp
ENSP00000591734
resolver
ensp
ENSP00000591735
resolver
ensp
ENSP00000591736
resolver
enst
ENST00000272521
resolver
enst
ENST00000401466
resolver
enst
ENST00000424086
resolver
enst
ENST00000867107
resolver
enst
ENST00000867108
resolver
enst
ENST00000867109
resolver
enst
ENST00000867110
resolver
enst
ENST00000867111
resolver
enst
ENST00000921671
resolver
enst
ENST00000921672
resolver
enst
ENST00000921673
resolver
enst
ENST00000921674
resolver
enst
ENST00000921675
resolver
enst
ENST00000921676
resolver
enst
ENST00000921677
resolver
genesymbol
TMEM177
resolver
hgnc
HGNC:28143
resolver
uniprot
Q9BT20
resolver
uniprot_entry
TM177_HUMAN
resolver
uniprot_sec
Q9BT20
resolver
amino_acid_sequence
MAGPLWRTAAFVQRHRTGLLVGSCAGLFGVPISYHLFPDPVVQWLYQYWPQGQPAPLPPQLQSLFQEVLQDIGVPSGHCYKPFTTFTFQPVSAGFPRLPAGAVVGIPASFLGDLVINTNHPVVIHGHTVDWRSPAGARLRASLTLSREAQKFALAREVVYLESSTTAVHALLAPACLAGTWALGVGAKYTLGLHAGPMNLRAAFSLVAAVAGFVAYAFSQDSLTHAVESWLDRRTASLSAAYACGGVEFYEKLLSGNLALRSLLGKDGEKLYTPSGNIVPRHLFRIKHLPYTTRRDSVLQMWRGMLNPGRS
uniprot
proteins
function
FUNCTION: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein. {ECO:0000269|PubMed:29154948}.
uniprot
proteins
mass_dalton
33760
uniprot
proteins
protein_family
TMEM177 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
29154948
uniprot
proteins
sequence_length
311
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:29154948}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 198..218; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins