Dohh
entrez
314644
canonical
uniprot
Q5PPJ4
canonical
ensembl
ENSRNOG00000004259
resolver
ensembl
ENSRNOG00055032747
resolver
ensembl
ENSRNOG00060032309
resolver
ensembl
ENSRNOG00065021680
resolver
ensp
ENSRNOP00000005640
resolver
ensp
ENSRNOP00055046729
resolver
ensp
ENSRNOP00060046287
resolver
ensp
ENSRNOP00065029712
resolver
enst
ENSRNOT00000005640
resolver
enst
ENSRNOT00055056623
resolver
enst
ENSRNOT00060056007
resolver
enst
ENSRNOT00065036893
resolver
genesymbol
Dohh
resolver
uniprot_entry
DOHH_RAT
resolver
amino_acid_sequence
MVTEQEVEAIGKTLVDSTQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDPRAIPVLVSVLQDRNQEPMVRHEAGEALGAIGNPKVLGLLKQYSTDPVVEVAETCQLAVRRLEWLQQHPGEATCAGPYLSVDPAPPAAEGDVGRLRETLLDEAQPLFERYRAMFALRNVGGKEAALALAEGLKCGSALFRHEVGYVLGQLQHEAAVSELAATLARTTESPMVRHECAEALGAIARPACLAALREYITDPERVVRESCEVALDMYEYENGQDFQYADGLERLRPPP
uniprot
proteins
ec_number
1.14.99.29
uniprot
proteins
function
FUNCTION: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. {ECO:0000250|UniProtKB:Q99LN9, ECO:0000255|HAMAP-Rule:MF_03101}.
uniprot
proteins
mass_dalton
33077
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; eIF5A hypusination. {ECO:0000250|UniProtKB:Q9BU89, ECO:0000255|HAMAP-Rule:MF_03101}.
uniprot
proteins
protein_family
Deoxyhypusine hydroxylase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
302
uniprot
proteins