PTGER2
entrez
5732
canonical
uniprot
P43116
canonical
ensembl
ENSG00000125384
resolver
ensp
ENSP00000245457
resolver
enst
ENST00000245457
resolver
genesymbol
PTGER2
resolver
hgnc
HGNC:9594
resolver
uniprot
D3DSC0
resolver
uniprot
Q52LG8
resolver
uniprot_entry
PE2R2_HUMAN
resolver
uniprot_sec
D3DSC0
resolver
uniprot_sec
Q52LG8
resolver
amino_acid_sequence
MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
uniprot
proteins
function
FUNCTION: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
uniprot
proteins
mass_dalton
39761
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10521663
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8078484
uniprot
proteins
sequence_length
358
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 24..47; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 66..91; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 112..132; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 152..176; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 199..223; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 263..286; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 300..323; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins