Relt
entrez
320100
canonical
uniprot
Q8BX43
canonical
ensembl
ENSMUSG00000008318
resolver
ensp
ENSMUSP00000008462
resolver
ensp
ENSMUSP00000211636
resolver
ensp
ENSMUSP00000211642
resolver
ensp
ENSMUSP00000211643
resolver
ensp
ENSMUSP00000211647
resolver
enst
ENSMUST00000008462
resolver
genesymbol
Relt
resolver
genesymbol_syn
Tnfrsf19l
resolver
uniprot
Q497Z8
resolver
uniprot
Q8BTV0
resolver
uniprot_entry
TR19L_MOUSE
resolver
uniprot_sec
Q497Z8
resolver
uniprot_sec
Q8BTV0
resolver
amino_acid_sequence
MSLQGLMMKRTLLCWPLSCLFVLLPWPLATPTPITPWLCPPGKEPDPDPGQGTLCRTCPPGTFSASWNSYPCQPHYRCSLQKRLEAQAGTATHDTMCGDCQHGWFGPQGVPHVPCQPCSKAPPSTGGCDESGRRGRRGVEVAAGTSSNGEPRQPGNGTRAGGPEETAAQYAVIAIVPVFCLMGLLGILVCNLLKRKGYHCTAQKEVGPSPGGGGSGINPAYRTEDANEDTIGVLVRLITEKKENAAALEELLKEYHSKQLVQTSHRPVPRLLPASPSIPHICPHHHHLHTVQGLASLSGPCCSRCSQKWPEVLLSPEAAAATTPAPTLLPTASRAPKASAKPGRQGEITILSVGRFRVARIPEQRTSSLLSEVKTITEAGPSEGDLPDSPQPGLPPEQRALLGSGGSHTKWLKPPAENKAEENRYVVRLSESNLVI
uniprot
proteins
function
FUNCTION: May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation (PubMed:30506946). {ECO:0000250|UniProtKB:Q969Z4, ECO:0000269|PubMed:30506946}.
uniprot
proteins
mass_dalton
46518
uniprot
proteins
mutagenesis
MUTAGEN 396..436; /note="Missing: Enamel of mutant mice has a rough surface and is hypomineralized."; /evidence="ECO:0000269|PubMed:30506946
uniprot
proteins
post_translational_modification
PTM: Phosphorylated in vitro by OXSR1. Phosphorylated by STK39. {ECO:0000250|UniProtKB:Q969Z4}.
uniprot
proteins
protein_family
RELT family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
30506946
uniprot
proteins
sequence_length
436
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q969Z4}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q969Z4}. Cytoplasm {ECO:0000250|UniProtKB:Q969Z4}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q969Z4}.
uniprot
proteins
transmembrane_region
TRANSMEM 170..190; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins