Lgi3
entrez
213469
canonical
uniprot
Q8K406
canonical
ensembl
ENSMUSG00000033595
resolver
ensp
ENSMUSP00000046705
resolver
enst
ENSMUST00000047331
resolver
genesymbol
Lgi3
resolver
uniprot
Q3V1R3
resolver
uniprot_entry
LGI3_MOUSE
resolver
uniprot_entry
Q3V1R3_MOUSE
resolver
amino_acid_sequence
MAGLRARRGPGRRLLVLSTLGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKSVPKNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFIGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILSDLDLRGNALNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLSFPAVSAEPFLYSSDLYLALAQPGASACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDGQLYVVVAQLFGGSYIYHWDPNTTRFTKLQDIDPQRVRKPNDLEAFRIDGDWFFAVADSSKAGATSLYRWHQNGFYSHQALHAWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRSQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGHRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHVVVDLSA
uniprot
proteins
function
FUNCTION: May participate in the regulation of neuronal exocytosis. {ECO:0000269|PubMed:18760330}.
uniprot
proteins
mass_dalton
61818
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18760330
uniprot
proteins
pubmed
19833108
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
35948005
uniprot
proteins
sequence_length
548
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8N145}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000269|PubMed:18760330}. Synapse, synaptosome {ECO:0000269|PubMed:18760330}. Cell projection, axon {ECO:0000269|PubMed:35948005}. Note=Found in the synaptosomal membrane fraction. Within peripheral myelinated axons, LGI3 is highly expressed at the juxtaparanodal membrane and colocalizes with the voltage-gated potassium channels Kv1.1 (KCNA1) and Kv1.2 (KCNA2), and CNTNAP2, DLG4, ADAM22 and ADAM23 (PubMed:35948005). {ECO:0000269|PubMed:35948005}.
uniprot
proteins