Api5
entrez
11800
canonical
uniprot
O35841
canonical
ensembl
ENSMUSG00000027193
resolver
ensp
ENSMUSP00000028617
resolver
ensp
ENSMUSP00000263282
resolver
ensp
ENSMUSP00000263283
resolver
enst
ENSMUST00000028617
resolver
genesymbol
Api5
resolver
uniprot
Q3U517
resolver
uniprot
Q3UYQ4
resolver
uniprot
Q922L2
resolver
uniprot_entry
API5_MOUSE
resolver
uniprot_entry
Q3UYQ4_MOUSE
resolver
uniprot_sec
Q3U517
resolver
uniprot_sec
Q922L2
resolver
amino_acid_sequence
MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQAFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRTSEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLSNFNYERSLQGK
uniprot
proteins
function
FUNCTION: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
56785
uniprot
proteins
post_translational_modification
PTM: Acetylation at Lys-251 impairs antiapoptotic function. {ECO:0000250}.
uniprot
proteins
protein_family
API5 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9307294
uniprot
proteins
pubmed
9918813
uniprot
proteins
sequence_length
504
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly nuclear.
uniprot
proteins