Rxylt1
entrez
216395
canonical
uniprot
Q8VDX6
canonical
ensembl
ENSMUSG00000034620
resolver
ensp
ENSMUSP00000119308
resolver
ensp
ENSMUSP00000184622
resolver
enst
ENSMUST00000140299
resolver
genesymbol
Rxylt1
resolver
genesymbol_syn
Tmem5
resolver
uniprot
Q8BVJ1
resolver
uniprot
Q8R566
resolver
uniprot_entry
Q8BVJ1_MOUSE
resolver
uniprot_entry
RXLT1_MOUSE
resolver
uniprot_sec
Q8R566
resolver
amino_acid_sequence
MRLTRTRLCSLLVALYCLFSIYAAYHVFFGRRRRPLGTTSRNSRKAAAAQAKERRGREQSALESEEWNPWEGDEKNEQRHRVKTNLQILNKSTKEKIEHRVQIWGKAAIGLYLWEHIFEGTLDPADVTAQWREGQSVVGRTHYSFITGPAVVPGYFSIDVDNVVLVLNGREKAKIFHATQWLIYAQNLMKTQKLQHLAVVLLGNEHCENDWIMQFLKRNGGFVDLLFITYDSPWINGADILQWPLGVATYRQFPVVEASWTMLHDERPYICNFLGTAYENSSRQALMNILKQDGNDKLCWVSAREQWQPQETNESLKNYQDALLHSDLTLCPVGVNTECYRIYEACSFGSIPVVEDVMTAGHCGNTTSQHSAPLQLLKAMGAPFIFIKNWKELPAILEKEKTISLQEKIQRRKVLLHWYQHFKTELKWKFTKILESSFFINNKV
uniprot
proteins
ec_number
2.4.2.61
uniprot
proteins
function
FUNCTION: Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan. Participates in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. {ECO:0000250|UniProtKB:Q9Y2B1}.
uniprot
proteins
mass_dalton
51386
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000250|UniProtKB:Q9Y2B1}.
uniprot
proteins
protein_family
RXYLT1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
444
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9Y2B1}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9Y2B1}.
uniprot
proteins
transmembrane_region
TRANSMEM 10..30; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins