Sult1c2
entrez
69083
canonical
uniprot
Q9D939
canonical
ensembl
ENSMUSG00000023122
resolver
ensp
ENSMUSP00000023886
resolver
enst
ENSMUST00000023886
resolver
genesymbol
Sult1c2
resolver
genesymbol_syn
Sult1c1
resolver
uniprot
Q3UNA9
resolver
uniprot
Q8R210
resolver
uniprot_entry
ST1C2_MOUSE
resolver
uniprot_sec
Q3UNA9
resolver
uniprot_sec
Q8R210
resolver
amino_acid_sequence
MALTPELSRQTKLKEVAGIPLQAPTVDNWRQIQTFEAKPDDLLICTYPKSGTTWIQEIVDMIEQNGDVEKCRRTIIQHRHPFIEWARPPQPSGVDKANEMPAPRILRTHLPTQLLPPSFWTNNCKFLYVARNAKDCMVSYYHFYRMSQVLPEPGTWDEYFETFINGKVSWGSWFDHVKGWWEIRDKYQILFLFYEDMKRNPKHEIQKVMQFMGKNLDEDVVDKIVLETSFEKMKENPMTNRSTAPKSILDQSISPFMRKGTVGDWKNHFTVAQNERFDEIYKQKMGRTSLNFSMEL
uniprot
proteins
ec_number
2.8.2.1
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the sulfate conjugation of phenolic compounds (PubMed:12164856). Does not transfer sulfate to steroids, dopamine, acetaminophen, or alpha-naphthol (PubMed:12164856). Except in mitochondria, where it can add sulfate to cholesterol producing cholesterol sulfate, which alters mitochondrial membrane organization, and impacts protein complex mobility increasing state-III respiration, thereby modulating mitochondrial respiration (By similarity). Catalyzes the sulfation of the carcinogenic N-hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis (By similarity). {ECO:0000250|UniProtKB:O00338, ECO:0000250|UniProtKB:Q9WUW8, ECO:0000269|PubMed:12164856}.
uniprot
proteins
mass_dalton
34953
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
12164856
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
296
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O46503}. Lysosome {ECO:0000250|UniProtKB:Q9WUW8}. Mitochondrion {ECO:0000250|UniProtKB:Q9WUW8}.
uniprot
proteins