Cc2d1a
entrez
288908
canonical
uniprot
Q66HA5
canonical
ensembl
ENSRNOG00000006747
resolver
ensp
ENSRNOP00000045667
resolver
enst
ENSRNOT00000045180
resolver
genesymbol
Cc2d1a
resolver
uniprot
A0A8L2QP71
resolver
uniprot_entry
A0A8L2QP71_RAT
resolver
uniprot_entry
C2D1A_RAT
resolver
amino_acid_sequence
MHKRNGPQAPPGRGAVTARQLGLLVDFSPDGLMIPEDGVNDEELEAEFLALVGGQPQALEKLKGKGPLPMEAIEKMARLCMRDLDEDEEGTDEDVEADEDLLAELNEVLGEERKAVEPAMPVVQPKPSSPNPGIEATLQERLILYQSAVESARQAGDSAKMRRYDRGLKTLENLLVSAKKGNTINEADIPPPVASGKGPAIGHSHTHTTSHLAPVSPPAPEPSVTLEAPSTTAQTSAKPQLSPDPCSPLARLQSLQHEYKVAALRAKHQDDTATAARYLRVSKSFDPVLEALSRGELVDLSRLPPPPDQLSPEPPLPAAQPVTPASTLTRPEVPQPPKNLLEALEQRMERYHVAAAQAKAKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPIQGLESAEPSQQSLVGVLETAMKLANHEEGSDEEEEETPKKNTPAASTAQPKASPSRAPPSGPAPAGKAASKGTSTRAQQQLAFLEGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDIAKVPPAPVNKDDFVLVQRPGPGMSQEAVRRYGELTKLLRQQHEMCLNHSTQFTHLGNIAETIKFEKLAEDCKRSMDTLKQAFARSLPTPAARFEQRTFSVIKIFPDLSNNDMLLFIVKGINLPTPPGLSPSDLDAFVRFDFPYPNVEEAQKDKTSVIKSTDSPEFKEQFKLCINRGHRGFRRAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLDTLETACEVHEILEVLDGRRPTGGRLEVMVRIREPLTAQQLETTTERWLVIDHIPAAVPTVTGPKAKVPLIPASSKEAGNRSSRPLHSLSVLAFDQERLERKILALRQARRPVPPEVAQQYQDVVQRSQWQRAQLEQGGAALRREYASHLERQLHFYTEAARRLGYDGSREAAKEALYRRNLVESELQRLRR
uniprot
proteins
function
FUNCTION: Transcription factor that binds specifically to the DRE (dual repressor element) and represses 5-HT1A gene transcription though this element. Mediates HDAC-independent repression of HTR1A promoter. CAMK2G inhibits CC2D1a-induced repression of the HTR1A. May play a role in the altered regulation of 5-HT1A receptors associated with anxiety and major depression. Performs essential function in controlling functional maturation of synapses (By similarity). {ECO:0000250, ECO:0000269|PubMed:12917378}.
uniprot
proteins
mass_dalton
103587
uniprot
proteins
protein_family
CC2D1 family
uniprot
proteins
pubmed
12917378
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
941
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12917378}. Nucleus {ECO:0000269|PubMed:12917378}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q6P1N0}.
uniprot
proteins