Q17RH7
uniprot
Q17RH7
canonical
amino_acid_sequence
MQDPRHPQGLPLSPGLPKRQRQDRTIYNWKQQEVLENHFKEEQYPDYDTRQELAEMLNLREYQVQVWFKNRRAKRSRERWFQKQLQQLQKHPQQQHPQQQHPQQQLQQQQPQQQPQQQQPQQQPQQQQPQQQQLHQQPQ
uniprot
proteins
function
FUNCTION: Transcription factor required for zygotic genome activation (ZGA), a critical event in early embryonic development during which the developmental control passes from maternally provided mRNAs to the expression of the zygotic genome after fertilization (PubMed:36074823). Protein produced from maternal transcripts that binds and activates expression of key ZGA marker genes, such as NANOGNB, ZSCAN4, DUXB, KLF5 and DPPA3 (PubMed:36074823). Binds to regulatory DNA sequences containing a 5'-TAATCC-3' sequence motif (By similarity). {ECO:0000250|UniProtKB:Q8N7U7, ECO:0000269|PubMed:36074823}.
uniprot
proteins
mass_dalton
17344
uniprot
proteins
protein_family
Paired homeobox family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
36074823
uniprot
proteins
sequence_length
139
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:36074823}.
uniprot
proteins