SPRR1B
entrez
6699
canonical
uniprot
P22528
canonical
ensembl
ENSG00000169469
resolver
ensp
ENSP00000306461
resolver
enst
ENST00000307098
resolver
genesymbol
SPRR1B
resolver
hgnc
HGNC:11260
resolver
uniprot
B2R5H7
resolver
uniprot
P22529
resolver
uniprot
P22530
resolver
uniprot
Q5T524
resolver
uniprot_entry
SPR1B_HUMAN
resolver
uniprot_sec
B2R5H7
resolver
uniprot_sec
P22529
resolver
uniprot_sec
P22530
resolver
uniprot_sec
Q5T524
resolver
amino_acid_sequence
MSSQQQKQPCTPPPQLQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCHPKVPEPCQPKVPEPCHPKVPEPCPSIVTPAPAQQKTKQK
uniprot
proteins
function
FUNCTION: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
uniprot
proteins
mass_dalton
9888
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
Cornifin (SPRR) family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
3133554
uniprot
proteins
pubmed
7829876
uniprot
proteins
pubmed
8388378
uniprot
proteins
sequence_length
89
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins