Elp2
entrez
58523
canonical
uniprot
Q91WG4
canonical
ensembl
ENSMUSG00000024271
resolver
ensp
ENSMUSP00000157109
resolver
ensp
ENSMUSP00000284080
resolver
genesymbol
Elp2
resolver
genesymbol_syn
Statip1
resolver
uniprot
Q3TIH5
resolver
uniprot
Q3TIT0
resolver
uniprot
Q8CBW6
resolver
uniprot
Q9ESY7
resolver
uniprot_entry
ELP2_MOUSE
resolver
uniprot_sec
Q3TIH5
resolver
uniprot_sec
Q3TIT0
resolver
uniprot_sec
Q8CBW6
resolver
uniprot_sec
Q9ESY7
resolver
amino_acid_sequence
MVSSVLEVSHVFCCPNRVRGALSWNTGPGGLLAFGTSCSVVLYDPQKKVVITNLNGHTARVNCLQWIRTEDGSPSNELVSGGSDNRVIHWELENNQVLKSVRLQGHEGPVCAVHAIYQSGPSEGEQHALIASAASDSTVRIWSKKGSEVKYLQTLSFRDGFVLSVCLAILPGTNVPVLACGDDDCRIHLYIQQDDQFQKALSLCGHEDWIRGVEWATFGRDLFLASCSQDCLIRIWRLYMKPASFETKDGSLRLKENTFTIKDGGVRTTVAVTLETVLAGHENWVNAVHWQPSFYKDGVLQQPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFGENGTMIIAHAFHGALHLWKQSTVNPRQWAPEIVISGHFDGVQDLMWDPEGEFIITTSTDQTTRLFAPWKKKDQKDRSQVTWHEIARPQIHGYNIKCLAMIDRFQFVSGADEKVLRVFSAPRNFVENFSVISRQSLSHMLCDDQDLPEGATVPALGLSNKALFQGDIASQPFEEDELISPAFGSPQVTFQPAVLNEPPTEDHLLQNTLWPEIQKLYGHGYEIVCVACNNSKTLLASACKASQKEHAAIILWSTASWKQVQSLAFHTLTVTQMTFSPDDKFLLAVSRDRTWSLWKRQDATSSEFDPFFSLFAFTNKITSVHSRIIWSCDWSPDNKYFFTGSRDKKVVVWGECKSSHNPMEHPIRPCSSILDVGSSVTAVSVCPVLNPAQRYIVAIGLESGKICIYSWNKTNQEINDWTSCVETNPSQSHSLGIRRLCWKSCSDDDDDDDDDDTEQSEEGPEWLHFASCGEDHTVKIYRVNRRAL
uniprot
proteins
function
FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. {ECO:0000250|UniProtKB:Q6IA86}.
uniprot
proteins
mass_dalton
93093
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. {ECO:0000250|UniProtKB:Q6IA86}.
uniprot
proteins
protein_family
WD repeat ELP2 family
uniprot
proteins
pubmed
10954736
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
831
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q6IA86}. Nucleus {ECO:0000250|UniProtKB:Q6IA86}.
uniprot
proteins