Ptgir
entrez
19222
canonical
uniprot
P43252
canonical
ensembl
ENSMUSG00000043017
resolver
ensp
ENSMUSP00000083270
resolver
ensp
ENSMUSP00000122080
resolver
enst
ENSMUST00000086101
resolver
enst
ENSMUST00000144408
resolver
genesymbol
Ptgir
resolver
uniprot
E9PY53
resolver
uniprot
Q52KE5
resolver
uniprot
Q8CC99
resolver
uniprot_entry
E9PY53_MOUSE
resolver
uniprot_entry
PI2R_MOUSE
resolver
uniprot_entry
Q8CC99_MOUSE
resolver
uniprot_sec
Q52KE5
resolver
amino_acid_sequence
MMASDGHPGPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSAQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLYHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSREMGDLLAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQAPLSRPASGRRDPPAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC
uniprot
proteins
function
FUNCTION: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
uniprot
proteins
mass_dalton
44463
uniprot
proteins
mutagenesis
MUTAGEN 412; /note="C->S: Abolishes isoprenylation."; /evidence="ECO:0000269|PubMed:10446129
uniprot
proteins
post_translational_modification
PTM: Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. {ECO:0000269|PubMed:10446129}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10446129
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
23457445
uniprot
proteins
pubmed
7511597
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 45..66; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 80..104; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 123..143; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 163..186; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 216..236; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 264..288; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 302..322; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins