Atp5mc2
entrez
171082
canonical
uniprot
Q06646
canonical
ensembl
ENSRNOG00000015320
resolver
ensembl
ENSRNOG00065022849
resolver
ensp
ENSRNOP00000020675
resolver
ensp
ENSRNOP00065031706
resolver
enst
ENSRNOT00000020676
resolver
enst
ENSRNOT00065039051
resolver
genesymbol
Atp5mc2
resolver
genesymbol_syn
Atp5g2
resolver
uniprot
A2VCW6
resolver
uniprot_entry
AT5G2_RAT
resolver
uniprot_sec
A2VCW6
resolver
amino_acid_sequence
MYACSKFVSTRSLIRSTSQLLSRPLSAVELKRPQMPTDEGLSCLAVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
uniprot
proteins
disease_involvement
DISEASE: Note=This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease).
uniprot
proteins
function
FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
uniprot
proteins
mass_dalton
14918
uniprot
proteins
post_translational_modification
PTM: Trimethylated by ATPSCKMT at Lys-109. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. {ECO:0000269|PubMed:30530489}.
uniprot
proteins
protein_family
ATPase C chain family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
30530489
uniprot
proteins
pubmed
8448208
uniprot
proteins
sequence_length
141
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins