Lrfn2
entrez
70530
canonical
uniprot
Q80TG9
canonical
ensembl
ENSMUSG00000040490
resolver
ensp
ENSMUSP00000047573
resolver
enst
ENSMUST00000046254
resolver
genesymbol
Lrfn2
resolver
genesymbol_syn
Kiaa1246
resolver
genesymbol_syn
Salm1
resolver
uniprot
B9EIF8
resolver
uniprot
Q9CYK3
resolver
uniprot_entry
LRFN2_MOUSE
resolver
uniprot_sec
B9EIF8
resolver
uniprot_sec
Q9CYK3
resolver
amino_acid_sequence
METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGSLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDTPGKMAAATVSNVYSQTNGSQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLGRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSSRGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAVPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV
uniprot
proteins
function
FUNCTION: Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A (By similarity). May play a role in redistributing DLG4 to the cell periphery. {ECO:0000250, ECO:0000269|PubMed:16828986}.
uniprot
proteins
mass_dalton
84963
uniprot
proteins
mutagenesis
MUTAGEN 787..788; /note="Missing: Loss of DLG4-binding."; /evidence="ECO:0000269|PubMed:16828986
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000269|PubMed:16828986}.
uniprot
proteins
protein_family
LRFN family
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16828986
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
788
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:16828986}; Single-pass type I membrane protein {ECO:0000269|PubMed:16828986}. Synapse {ECO:0000269|PubMed:16828986}. Postsynaptic cell membrane {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 535..555; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins