Sult1b1
entrez
56362
canonical
uniprot
Q9QWG7
canonical
ensembl
ENSMUSG00000029269
resolver
ensp
ENSMUSP00000031199
resolver
ensp
ENSMUSP00000112679
resolver
ensp
ENSMUSP00000112844
resolver
ensp
ENSMUSP00000361560
resolver
genesymbol
Sult1b1
resolver
uniprot
Q8C301
resolver
uniprot
Q9Z2T0
resolver
uniprot_entry
ST1B1_MOUSE
resolver
uniprot_sec
Q8C301
resolver
uniprot_sec
Q9Z2T0
resolver
amino_acid_sequence
MSASEDVWRKDLKMIHGYPMIYAFALNWERIEEFQSTPGDIVITTYPKSGTTWLSEIVDMVLNDGNVEKCKRDVITSKVPMLELSVPGIRISGVELLKKTPSPRIIKTHLPIDLLPKSFWENKCKMIYLARNGKDVAVSYYHFDLMNSINPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREEHPLLYLYYEELKQNPKKEIKKIASFLDKTLDEEALDRIVHHTSFEMMKENPLVNYTHLPTAMMDHSKSPFMRKGIVGDWKNYFTMTQTEQFDAVYKKKMSGTTLEFCTDIQSA
uniprot
proteins
ec_number
2.8.2.1
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3) (PubMed:9644246). May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system (By similarity). {ECO:0000250|UniProtKB:O43704, ECO:0000269|PubMed:9644246}.
uniprot
proteins
mass_dalton
34901
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9644246
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O43704}.
uniprot
proteins