Ice1
entrez
218333
canonical
uniprot
E9Q286
canonical
ensembl
ENSMUSG00000034525
resolver
ensp
ENSMUSP00000036482
resolver
enst
ENSMUST00000043493
resolver
genesymbol
Ice1
resolver
genesymbol_syn
Kiaa0947
resolver
uniprot
Q6ZQ20
resolver
uniprot_entry
ICE1_MOUSE
resolver
uniprot_sec
Q6ZQ20
resolver
amino_acid_sequence
MMPGETHPAAPGPADLARCQGCASLQQNLNEYVEALIALKQKIINTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSLKAELEEKKSSLKLYQDTHQEYARVKEECLRTDAQKKKLEAKVKKLEEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKNEKELRHIGTQISSDSHGSIDKRKVKVLLKELWLCVNTAHRLSGEGGRRIPEKPAKGSSAARASEQDELLPVQGGPARAADMRSFFSKLSMEMEGDFSSSESAEEELPSGASPSTEHAFCEERHSEVSGQRPDDGNRTNVYDHEHFFDDDLQAAIDFFKLPPPLLSPVPSPPPMASGSLPSSLAPESFFGEFTDSSDSDSVPPRDSMESALEDYTAESRAYFDLLEKIKRSDQYVKKPGSLEATQAVNSLTPLGFVTGRTALGEPSAAASLAQGRHWTESSEFVRDRGDSVEEAERMVEAREVDKSVQVGKGLLKHNRKLWLEMASRGPARKKEAGAGESEICFSSLGKRTFSELIESEGKTLSSKALCPSQSEFSKRTLTDGSASKSPCVTGSGRFQRRERDVRESTPQSGICAAAAGRGHSARLPSSSSATSVPVSVCSNHQTPWPGCVSVGTPAEGTCTEQKSPTRTLNTFLLRSEPTACFPKENDPENSLSTLSPKSKLGTSTFSDWKSRGLESFSTLKSTAKGHSLPQSVFPKPTGGGQCKGRGPGATLILPKSDWTSLARSQAGFTRRSSGSADSTSWHRSDVLRRGSGGSPRASSEYQQRTRLQLEKATPASQNSSLTAMHGPSGESTIPPESNAAAALLPNQVSVITKQARPRRVLGSSLEPWQPHGNTLSPAVNGGKETGLMPSVSACVGDGDPIAQVPEQIADKETPSPEVSVSWRNPICDSPSDSLLAENFSCSTDRKLPFSSEDNIFQCAMNEHLQQKPTKSPQTTQSGASRLEAGELLPSGVTSGVFPAEQVPHGPHHQADTEAPVVARESHSAPQNASAPPVVPSRGPLRARVPTVPVCPSSLSRAEEETQGTSQSSLPGASYCYTGIRERGEEDTEVEDEAVSCSEGEHEAEAVMGRRQQEQAEDSHRPLGDPEAGVGEAGHPSDVGDLTSALEECNLSTLLYIDKLSTSEVVMVLESCQLGDYSSRVSASECASKGSLSEEMNTELRQSEISRKKCGKRLWEEKLLRASEEWAESEGDDSCGRTSCQHAQCPLEVPSDVLTKTGEELDTNPVDCGGTDTEHALLESTHHSQAAEDLTEDALPEETSSPMPHTAELPDPSAVDGGGSSPLSSRSDPEHIQSSYEDEPNSGECLSIGEEGLAEPGELLTLSSDSSTPPRLEQSSDCVAETAFRYQISAVTSEVISVLINKDQDLVIEKGDNWTIISGVAISPGMEQVVLCDTLGDAASSQDQGGLDDGSMEKSPEASPSGPLPQEPPCGGDLSGAQEDISSNGQSANFDKSRLRNRPVKPSIWIRSQIYDQTLETEKVASDHTYYNWKLEPLGKNKPRSKISNKDQASKLAKTLVLNRGEVHLNEVPQPASGEGTNIKLPRSQAQPIMAGTDRSTPTNCSPDTLSKIRQEVGPPLPPLLPPLIATPPRSSQTLSPLVPNSGPSSRSSPAGHVSPLCEVPGPPVLSPWPEELQQASPLDPSPSPSTAAASGRIVSSPLQFCAATPKHALPVPGRLPSCAPGHAAVSGPQQENSVKILDTMYPELSARARTLSLLKGNMQLSRGSTVDGKVLPGRVSALLGLKAITSTSTAFVLTGGSSGADGSQGKSQDSGVQQDAGGKRTLAVSMLRSAKRLRLDNKSPEPDTREVTGEGVPEDPQGGSPLAEVVPAEEEQADVPVCSAASLLRVNPREMAESYNIAITRALRKIAESSFDLLPVIRSHVYVGNISKKPVMRDQEKEVVYEFSTTNKHLGEYLLRSILSELKIQKTSLDHSYIHALCRVYVGICRQLGDLERARLFCYSLLKEDFPESEKLTLFIANMWREVFLSQSAISEAMQLVARQRARGEVLNCLRAFLSWEKNAPIDVGIVVSKLLLTIQLCPKTEFQSSEEFGEDLSANIWEYIFAIDLLCCHQRWIWTHDNIISKELWPVMDKWIKYRKGHSNIAYTPDVIVASVLRLIGRLGQLGLKEGFPTAVKNISSVIGMFIQHAQDEDIPWGVQLAAVYALCDLSPSNPAEISKILEAWRTQTSNAIPSAIVHCLEEVGSLSADGSAGCTSKGDSAP
uniprot
proteins
function
FUNCTION: Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
242254
uniprot
proteins
protein_family
ICE1 family
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
2241
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y2F5}. Nucleus, Cajal body {ECO:0000250|UniProtKB:Q9Y2F5}. Note=Colocalizes with COIL in subnuclear Cajal and histone locus bodies. Associates to transcriptionally active chromatin at snRNA genes. {ECO:0000250|UniProtKB:Q9Y2F5}.
uniprot
proteins