Faim2
entrez
72393
canonical
uniprot
Q8K097
canonical
ensembl
ENSMUSG00000023011
resolver
ensp
ENSMUSP00000023750
resolver
ensp
ENSMUSP00000155195
resolver
genesymbol
Faim2
resolver
genesymbol_syn
Kiaa0950
resolver
genesymbol_syn
Lfg
resolver
genesymbol_syn
Lfg2
resolver
genesymbol_syn
Nmp35
resolver
uniprot
Q3TY22
resolver
uniprot
Q8K1F6
resolver
uniprot
Q9D6K4
resolver
uniprot_entry
LFG2_MOUSE
resolver
uniprot_sec
Q3TY22
resolver
uniprot_sec
Q8K1F6
resolver
uniprot_sec
Q9D6K4
resolver
amino_acid_sequence
MTQGKLSVANKAPGTEGQQHQANGEKKDAPAVPSAPPSYEEATSGEGLKAGTFPQGPTAVPLHPSWAYVDPSGSSGYEGGFPAGHHEHFTTFSWDDQKVRRLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLVITALVCLSVTIFSFQTKFDFTSCQGVLFVLLMTLFFSGLLLAVLLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE
uniprot
proteins
function
FUNCTION: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. Plays a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. {ECO:0000269|PubMed:17635665, ECO:0000269|PubMed:21209208, ECO:0000269|PubMed:21957071}.
uniprot
proteins
mass_dalton
35258
uniprot
proteins
protein_family
BI1 family
uniprot
proteins
protein_family
LFG subfamily
uniprot
proteins
pubmed
12693553
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17635665
uniprot
proteins
pubmed
19784873
uniprot
proteins
pubmed
21209208
uniprot
proteins
pubmed
21957071
uniprot
proteins
sequence_length
317
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane raft {ECO:0000269|PubMed:17635665}. Postsynaptic cell membrane {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 107..127; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..159; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 166..186; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 195..215; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 252..272; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 291..311; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins