P21845
uniprot
P21845
canonical
amino_acid_sequence
MLKRRLLLLWALSLLASLVYSAPRPANQRVGIVGGHEASESKWPWQVSLRFKLNYWIHFCGGSLIHPQWVLTAAHCVGPHIKSPQLFRVQLREQYLYYGDQLLSLNRIVVHPHYYTAEGGADVALLELEVPVNVSTHIHPISLPPASETFPPGTSCWVTGWGDIDNDEPLPPPYPLKQVKVPIVENSLCDRKYHTGLYTGDDFPIVHDGMLCAGNTRRDSCQGDSGGPLVCKVKGTWLQAGVVSWGEGCAQPNKPGIYTRVTYYLDWIHRYVPEHS
uniprot
proteins
ec_number
3.4.21.59
uniprot
proteins
function
FUNCTION: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Plays a role in innate immunity. {ECO:0000269|PubMed:17456473}.
uniprot
proteins
mass_dalton
30927
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
protein_family
Tryptase subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16777228
uniprot
proteins
pubmed
17456473
uniprot
proteins
pubmed
17947660
uniprot
proteins
pubmed
1995638
uniprot
proteins
pubmed
2326280
uniprot
proteins
pubmed
7959952
uniprot
proteins
pubmed
8210998
uniprot
proteins
sequence_length
276
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Note=Released from the secretory granules upon mast cell activation. {ECO:0000250}.
uniprot
proteins