Rps23
entrez
124323
canonical
uniprot
P62268
canonical
ensembl
ENSRNOG00000016580
resolver
ensembl
ENSRNOG00065022794
resolver
ensembl
ENSRNOG00065026736
resolver
ensp
ENSRNOP00000022348
resolver
ensp
ENSRNOP00065031578
resolver
ensp
ENSRNOP00065037830
resolver
enst
ENSRNOT00000022348
resolver
enst
ENSRNOT00065038921
resolver
enst
ENSRNOT00065046110
resolver
genesymbol
Rps23
resolver
uniprot
P39028
resolver
uniprot_entry
RS23_RAT
resolver
uniprot_sec
P39028
resolver
amino_acid_sequence
MGKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS
uniprot
proteins
function
FUNCTION: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. {ECO:0000250|UniProtKB:P62266}.
uniprot
proteins
mass_dalton
15808
uniprot
proteins
post_translational_modification
PTM: Hydroxylation at Pro-62 affects translation termination efficiency. {ECO:0000250|UniProtKB:P62266}.
uniprot
proteins
protein_family
Universal ribosomal protein uS12 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8037726
uniprot
proteins
sequence_length
143
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62266}. Cytoplasm {ECO:0000250|UniProtKB:P62266}. Rough endoplasmic reticulum {ECO:0000250|UniProtKB:Q6SA96}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62266}. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity). {ECO:0000250|UniProtKB:P62266, ECO:0000250|UniProtKB:Q6SA96}.
uniprot
proteins