DUSP2
entrez
1844
canonical
uniprot
Q05923
canonical
ensembl
ENSG00000158050
resolver
ensp
ENSP00000288943
resolver
ensp
ENSP00000520821
resolver
enst
ENST00000288943
resolver
enst
ENST00000718436
resolver
genesymbol
DUSP2
resolver
genesymbol_syn
PAC1
resolver
hgnc
HGNC:3068
resolver
uniprot
Q53T45
resolver
uniprot_entry
DUSP2_HUMAN
resolver
uniprot_sec
Q53T45
resolver
amino_acid_sequence
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Dephosphorylates both phosphorylated Thr and Tyr residues in MAPK1, and dephosphorylation of phosphotyrosine is slightly faster than that of phosphothreonine (PubMed:8107850). Can dephosphorylate MAPK1 (By similarity). {ECO:0000250|UniProtKB:Q05922, ECO:0000269|PubMed:8107850}.
uniprot
proteins
mass_dalton
34400
uniprot
proteins
mutagenesis
MUTAGEN 257; /note="C->S: Loss of tyrosine phosphatase activity."; /evidence="ECO:0000269|PubMed:8107850
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
12575935
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
7590752
uniprot
proteins
pubmed
7681221
uniprot
proteins
pubmed
8107850
uniprot
proteins
sequence_length
314
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins