Pxylp1
entrez
315939
canonical
uniprot
Q66H78
canonical
ensembl
ENSRNOG00000012480
resolver
ensembl
ENSRNOG00055017549
resolver
ensembl
ENSRNOG00060008185
resolver
ensembl
ENSRNOG00065007446
resolver
ensp
ENSRNOP00000017085
resolver
ensp
ENSRNOP00000106723
resolver
ensp
ENSRNOP00055023852
resolver
ensp
ENSRNOP00060010335
resolver
ensp
ENSRNOP00065008483
resolver
enst
ENSRNOT00000017085
resolver
enst
ENSRNOT00000124727
resolver
enst
ENSRNOT00055029689
resolver
enst
ENSRNOT00060013559
resolver
enst
ENSRNOT00065011630
resolver
genesymbol
Pxylp1
resolver
genesymbol_syn
Acpl2
resolver
uniprot
A0ABK0LSI8
resolver
uniprot_entry
A0ABK0LSI8_RAT
resolver
uniprot_entry
PXYP1_RAT
resolver
amino_acid_sequence
MLYRNRFLVLLALAGLLAFLSLSLQFFHLIPVSTTKNGGSSKSRKRIMPDPVTEPPTVDPVYEALLYCNIPSVAEHSMEGHAPHHYKLVSVHVFIRHGDRYPLYAIPKTKRPEIDCTLVASRKPYHPKLEAFVGHMLKGSGASFESPLGSLPLYPNHPLCEMGELTQTGVVQHLQNGQLLRDIYLRKHKLLPNNWSSDQLYLETTGKSRTLQSGLALLYGFLPEFDWKKVYFKHQPSALFCSGSCYCPLRNQYLEKEQRRQYLLRLKNSDLERTYGEMAKIVDIPTKQLRAANPIDSMLCHFCHNVSFPCSRSGCLGMEHFKVIKTHQIEDERERHEKLLYFGYSLLGAHPILNQTVNRMQRAALGWRDELFTLYSAHDVTLSPILSALGLLEARFPRFAARLVFELWQDRQKPSEHSVRILYNGADVTFHTSFCHDFHKHSPKPMCPLENLVRFVKRDMFVALDGSSTNYYDACHGEGA
uniprot
proteins
ec_number
3.1.3.-
uniprot
proteins
function
FUNCTION: Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains. {ECO:0000250|UniProtKB:Q8TE99}.
uniprot
proteins
mass_dalton
54958
uniprot
proteins
protein_family
Histidine acid phosphatase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
480
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8TE99}; Single-pass type II membrane protein {ECO:0000255}. Note=Colocalizes to Golgi apparatus in a B3GAT3-dependent manner. {ECO:0000250|UniProtKB:Q8TE99}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..27; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins