Ostn
entrez
360730
canonical
uniprot
P61365
canonical
ensembl
ENSRNOG00000030462
resolver
ensembl
ENSRNOG00055004574
resolver
ensembl
ENSRNOG00060013043
resolver
ensembl
ENSRNOG00065003653
resolver
ensp
ENSRNOP00000043654
resolver
ensp
ENSRNOP00055005412
resolver
ensp
ENSRNOP00060017606
resolver
ensp
ENSRNOP00065003832
resolver
enst
ENSRNOT00000049841
resolver
enst
ENSRNOT00055007248
resolver
enst
ENSRNOT00060022219
resolver
enst
ENSRNOT00065005302
resolver
genesymbol
Ostn
resolver
uniprot_entry
OSTN_RAT
resolver
amino_acid_sequence
MLDWRLASAHFLLAMILMLWGSGKAFSVDLASEASEFGAESLQSPPTTREEKSATELAAKLLLLDDLVSLENDVFETKKKRSFSGFGSPLDRLSAGSVEHRGKQRRVVDHSKKRFGIPMDRIGRNRLSSSRG
uniprot
proteins
function
FUNCTION: Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C. May act as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle. {ECO:0000250|UniProtKB:P61364}.
uniprot
proteins
mass_dalton
14636
uniprot
proteins
protein_family
Osteocrin family
uniprot
proteins
pubmed
14523025
uniprot
proteins
pubmed
15044443
uniprot
proteins
pubmed
17951249
uniprot
proteins
sequence_length
132
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:14523025}.
uniprot
proteins