Pkd1l2
entrez
76645
canonical
uniprot
Q7TN88
canonical
ensembl
ENSMUSG00000034416
resolver
ensp
ENSMUSP00000104721
resolver
enst
ENSMUST00000109093
resolver
genesymbol
Pkd1l2
resolver
uniprot
E9QPG2
resolver
uniprot_entry
E9QPG2_MOUSE
resolver
uniprot_entry
PK1L2_MOUSE
resolver
amino_acid_sequence
MAGLVFLGLALSSGATVAKSEGGSLCSRSQVFFRDACYEFVPLEHTFPGAQGWCEGHGGHLAFIPDEDTQQFLQRHITQDREWWIGLTGGSGHNGTVGGSGTWLDTSNVNYSNWQEGQATPAPGSCGYIGSGPSSQWAALEDCTQTFAFVCEFGVGRSLACEGHNATMHCDSGEVILVQDAFYGHQTPYLCTRGIWPPSDLEGECGWVSVKDEVAGQCQGLQACQVAVDGTYFGDPCPTRGSYLWVQYQCLEGLRLVVPNGSFIFDNVTISLMWLLSPYTGNLSCVLSMGDGYTFDPYNPPSVSSNVTHQFSSPGEFTVFAECTTSEWHVTAQKQVILCEKVETPRITGCTGLAGAGVGLLCQAVFGEPLWVQVDLDGGAGATYAVLSHNRTLAEFTAQRGSQLYNLTLDRDIQEMLGPGRHHLKIQAVSNEGTGTASAPSGNFTVYFVEPLSGLRASWASDRVELGWDLVVNVSVARGTLEELTFEVAGLNANFSQEEESVGQSSGNYHVAVPAEGTFLVTVHVRNAFSELSLDIGNITVTASSSLQELSGINAEAKSGHKQDMKVFTEPELYVDPFTEVTLGWPDDDPGLNFHWSCGRCWAQWNACVGRQLLHTDQRLLVLHTFCLPPLNSAVTLHLAILRGQELEKETEQCLYVSAPLNLGPQISCEKNCRPVKADQDVLLTVTVGDETSVAVFSWYLDDTVPEEVEPLPAACRLRGFWPRSLTLLHSNSSVLLLNSSFLQTWGPVIPIRVTALTSHAYGEDTYMISMLPRPEVPACTIDPEEGSVLTSFTVSCSTPATLGPVEYCFCLPSGFCLHCGPEPALPAVYLPLGEEKDGFVLPVVISVTNRAGDIEQTQVAVKVGHSYTGVEDVTFQEMVSERIATALHQESGREQLLLFAKAVSSELNSEVQSPGSGQLGMDIKRKVRELMLRSLSVVTTGLQNMQRVQALAEVLREVTQRAEELTPAAQWEASCALQRATEALLVASTKVRPEDQRRQEATRAMFEAVGSVLEASLSHRSEEPMEANSSQVAYIVAQLLRVIDHFQSALLLGTLPGGLPAILVTPSISVYTDRIQPRSWQGSSVHTAAADSVTFTLPAATFLCPMEDSQEPVDIRMMSFSQNPFPSRSQFDVSGTVGGLRLTSSSGHPIPVKNLSQNIEILLPRISAHIEPKMLSLASREALSVNVTAGDTALGIQLHWGPGVPLILSLGYGYHPNETSYDAQTHLPPVAATGDLPTWILHPEDLPFGEGVYYLRVVPEADLESSSGRNLTVGITTFLAHCVFWDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFGSSFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVLIWARRKDIQDQAKVKVVVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDPDAAVFERGGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQRVSCCFSMLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFRNTRPRLPMGKDGRQKQGPPNLTPSAQPTEEGLLTPETGIQSLISSLFKALKVQPPASGWDSMNPVDINYLLTLMEDIICPESTEGPGFWEEAKGREDPITSTRGSVKPKENTWHPKPELAVRGLWKDSVYRRCLYLQLEHVERELQLLGPQGFLHHHSHAQALRQLHVLKGHLWGQPGTPALAYPSTSRVSKSPRGLPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSFVESVFITQPLKVLGFAAFFALVLKREDDEETLPLFPGHLSSPGPGVLFRSRRHSSERAYQPPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQGFSPVLGFRGFFEWANTTLVKNLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHREGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSEEQKSDQLSEEGEIADLLLVKILSFLGIRCKREETWSSSEQPELPPQALAPQPAQALSRV
uniprot
proteins
function
FUNCTION: May function as a G protein-coupled receptor. {ECO:0000250|UniProtKB:Q7Z443}.
uniprot
proteins
mass_dalton
271977
uniprot
proteins
post_translational_modification
PTM: Autoproteolytically processed at the GPS region of the GAIN-B domain; this cleavage modulates receptor activity. {ECO:0000255|PROSITE-ProRule:PRU00098}.
uniprot
proteins
protein_family
Polycystin family
uniprot
proteins
pubmed
12782129
uniprot
proteins
sequence_length
2461
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 1346..1366; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1554..1574; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1596..1616; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1816..1836; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1863..1883; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1940..1960; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 2186..2206; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 2222..2242; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 2273..2293; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 2315..2335; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 2380..2400; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins