SIGLEC6
entrez
946
canonical
uniprot
O43699
canonical
ensembl
ENSG00000105492
resolver
ensp
ENSP00000344064
resolver
ensp
ENSP00000345907
resolver
ensp
ENSP00000353071
resolver
ensp
ENSP00000375674
resolver
ensp
ENSP00000401502
resolver
ensp
ENSP00000410679
resolver
ensp
ENSP00000760503
resolver
ensp
ENSP00000760504
resolver
ensp
ENSP00000760505
resolver
ensp
ENSP00000760508
resolver
ensp
ENSP00000760512
resolver
ensp
ENSP00000760517
resolver
genesymbol
SIGLEC6
resolver
genesymbol_syn
CD33L
resolver
genesymbol_syn
CD33L1
resolver
genesymbol_syn
OBBP1
resolver
hgnc
HGNC:10875
resolver
uniprot
A8MV71
resolver
uniprot
B2RTS8
resolver
uniprot
C9JBE5
resolver
uniprot
F8WA78
resolver
uniprot
O15388
resolver
uniprot
O43700
resolver
uniprot_entry
SIGL6_HUMAN
resolver
uniprot_sec
A8MV71
resolver
uniprot_sec
B2RTS8
resolver
uniprot_sec
C9JBE5
resolver
uniprot_sec
F8WA78
resolver
uniprot_sec
O15388
resolver
uniprot_sec
O43700
resolver
amino_acid_sequence
MQGAQEASASEMLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLPTTLPASYYGYGYWFLEGADVPVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRLKSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPEGRAGGVLGAVWGASITTLVFLCVCFIFRVKTRRKKAAQPVQNTDDVNPVMVSGSRGHQHQFQTGIVSDHPAEAGPISEDEQELHYAVLHFHKVQPQEPKVTDTEYSEIKIHK
uniprot
proteins
function
FUNCTION: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
uniprot
proteins
mass_dalton
49913
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
protein_family
SIGLEC (sialic acid binding Ig-like lectin) family
uniprot
proteins
pubmed
10428856
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9465907
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
uniprot
proteins
transmembrane_region
TRANSMEM 348..368; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins