DIRAS2
entrez
54769
canonical
uniprot
Q96HU8
canonical
ensembl
ENSG00000165023
resolver
ensp
ENSP00000364919
resolver
enst
ENST00000375765
resolver
genesymbol
DIRAS2
resolver
hgnc
HGNC:19323
resolver
uniprot
B3KVM2
resolver
uniprot_entry
DIRA2_HUMAN
resolver
uniprot_sec
B3KVM2
resolver
amino_acid_sequence
MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM
uniprot
proteins
ec_number
3.6.5.-
uniprot
proteins
function
FUNCTION: Displays low GTPase activity and exists predominantly in the GTP-bound form. {ECO:0000269|PubMed:12194967}.
uniprot
proteins
mass_dalton
22485
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated by the ECS(ASB11) complex via 'Lys-11'-linked ubiquitin chains, leading to its degradation by the proteasome. {ECO:0000269|PubMed:38574733}.
uniprot
proteins
protein_family
Di-Ras family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
12194967
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
38574733
uniprot
proteins
sequence_length
199
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:12194967}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins