Kdm4b
entrez
193796
canonical
uniprot
Q91VY5
canonical
ensembl
ENSMUSG00000024201
resolver
ensp
ENSMUSP00000025036
resolver
ensp
ENSMUSP00000194964
resolver
ensp
ENSMUSP00000194967
resolver
ensp
ENSMUSP00000194969
resolver
ensp
ENSMUSP00000194970
resolver
ensp
ENSMUSP00000194971
resolver
ensp
ENSMUSP00000194972
resolver
ensp
ENSMUSP00000194973
resolver
ensp
ENSMUSP00000194977
resolver
ensp
ENSMUSP00000194979
resolver
genesymbol
Kdm4b
resolver
genesymbol_syn
Jhdm3b
resolver
genesymbol_syn
Jmjd2b
resolver
uniprot
Q3UR22
resolver
uniprot
Q6ZQ30
resolver
uniprot
Q99K42
resolver
uniprot_entry
KDM4B_MOUSE
resolver
uniprot_sec
Q3UR22
resolver
uniprot_sec
Q6ZQ30
resolver
uniprot_sec
Q99K42
resolver
amino_acid_sequence
MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSIKAKLLRRQISVKESRPWRKAEEERRREPTRRPGPASHRRRSQPKKSKPEESRSPGEATAGVSTLDEARGCSRGEAMPEDEEEEELLPSQGHEAEGVEEDGRGKPRPTKARNKKKTPSPSSPPLLSAPPALFPTEEVLRPPPQPKSPGPAMGPMAAEGGPPPTPLNVVPPGAPVEEAEVRPRPIIPMLYVLPRTSSTDGDREHSAHAQLAPMELGPEEENQAQAGDSQGTTPFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFLFSGEDDVTDPEALRSLLSLQWKNKAASFQAERKFNAAAALSEPYCAICTLFYPYSQSVQTERDSAVQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDDVKAAKRPRVASVLATTTEDTGRSPEYLSFMESLLQAQGRPGAPF
uniprot
proteins
ec_number
1.14.11.66
uniprot
proteins
function
FUNCTION: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate (By similarity). Plays a critical role in the development of the central nervous system (CNS). {ECO:0000250|UniProtKB:O94953, ECO:0000269|PubMed:27023172}.
uniprot
proteins
mass_dalton
121604
uniprot
proteins
protein_family
JHDM3 histone demethylase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
27023172
uniprot
proteins
sequence_length
1086
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537}.
uniprot
proteins