Tas1r3
entrez
170634
canonical
uniprot
Q923K1
canonical
ensembl
ENSRNOG00000019589
resolver
ensembl
ENSRNOG00055013753
resolver
ensembl
ENSRNOG00060004571
resolver
ensembl
ENSRNOG00065010226
resolver
ensp
ENSRNOP00000026671
resolver
ensp
ENSRNOP00055019241
resolver
ensp
ENSRNOP00060005712
resolver
ensp
ENSRNOP00065012530
resolver
enst
ENSRNOT00000026671
resolver
enst
ENSRNOT00055023637
resolver
enst
ENSRNOT00060007624
resolver
enst
ENSRNOT00065016486
resolver
genesymbol
Tas1r3
resolver
genesymbol_syn
T1r3
resolver
genesymbol_syn
Tr3
resolver
uniprot_entry
TS1R3_RAT
resolver
amino_acid_sequence
MPGLAILGLSLAAFLELGMGSSLCLSQQFKAQGDYILGGLFPLGTTEEATLNQRTQPNGILCTRFSPLGLFLAMAMKMAVEEINNGSALLPGLRLGYDLFDTCSEPVVTMKPSLMFMAKVGSQSIAAYCNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYSASMDRLSDRETFPSFFRTVPSDRVQLQAVVTLLQNFSWNWVAALGSDDDYGREGLSIFSGLANSRGICIAHEGLVPQHDTSGQQLGKVVDVLRQVNQSKVQVVVLFASARAVYSLFSYSILHDLSPKVWVASESWLTSDLVMTLPNIARVGTVLGFLQRGALLPEFSHYVETRLALAADPTFCASLKAELDLEERVMGPRCSQCDYIMLQNLSSGLMQNLSAGQLHHQIFATYAAVYSVAQALHNTLQCNVSHCHTSEPVQPWQLLENMYNMSFRARDLTLQFDAKGSVDMEYDLKMWVWQSPTPVLHTVGTFNGTLQLQHSKMYWPGNQVPVSQCSRQCKDGQVRRVKGFHSCCYDCVDCKAGSYRKHPDDFTCTPCGKDQWSPEKSTTCLPRRPKFLAWGEPAVLSLLLLLCLVLGLTLAALGLFVHYWDSPLVQASGGSLFCFGLICLGLFCLSVLLFPGRPRSASCLAQQPMAHLPLTGCLSTLFLQAAEIFVESELPLSWANWLCSYLRGPWAWLVVLLATLVEAALCAWYLMAFPPEVVTDWQVLPTEVLEHCRMRSWVSLGLVHITNAVLAFLCFLGTFLVQSQPGRYNRARGLTFAMLAYFIIWVSFVPLLANVQVAYQPAVQMGAILFCALGILATFHLPKCYVLLWLPELNTQEFFLGRSPKEASDGNSGSSEATRGHSE
uniprot
proteins
function
FUNCTION: Key component of the sweet and umami taste receptors (By similarity). TAS1R1 and TAS1R3 form the umami receptor and respond to the umami taste stimulus (the taste of monosodium glutamate) (By similarity). TAS1R2 and TAS1R3 form the sweet taste receptor and recognize diverse natural and synthetic sweeteners (By similarity). The sweet taste receptor has lower affinity for natural sugars than for synthetic sweeteners (By similarity). Essential for the recognition and response to the disaccharide trehalose (By similarity). Functions as a G protein-coupled receptor and primarily signals through the gustducin heterotrimer (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses (By similarity). {ECO:0000250|UniProtKB:Q49KI5, ECO:0000250|UniProtKB:Q7RTX0}.
uniprot
proteins
mass_dalton
94846
uniprot
proteins
protein_family
G protein-coupled receptor 3 family
uniprot
proteins
protein_family
TAS1R subfamily
uniprot
proteins
pubmed
11509186
uniprot
proteins
pubmed
11917125
uniprot
proteins
sequence_length
858
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7RTX0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q7RTX0}.
uniprot
proteins
transmembrane_region
TRANSMEM 576..596; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:Q7RTX0"; TRANSMEM 609..629; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:Q7RTX0"; TRANSMEM 645..665; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:Q7RTX0"; TRANSMEM 688..708; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:Q7RTX0"; TRANSMEM 735..755; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:Q7RTX0"; TRANSMEM 768..788; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:Q7RTX0"; TRANSMEM 795..818; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:Q7RTX0
uniprot
proteins