PTPRR
entrez
5801
canonical
uniprot
Q15256
canonical
ensembl
ENSG00000153233
resolver
ensp
ENSP00000283228
resolver
ensp
ENSP00000339605
resolver
ensp
ENSP00000368054
resolver
ensp
ENSP00000391750
resolver
genesymbol
PTPRR
resolver
genesymbol_syn
ECPTP
resolver
genesymbol_syn
PTPRQ
resolver
hgnc
HGNC:9680
resolver
uniprot
B2R5Z7
resolver
uniprot
B7Z3J1
resolver
uniprot
B7Z998
resolver
uniprot
F5GXR7
resolver
uniprot
O00342
resolver
uniprot
Q92682
resolver
uniprot
Q9UE65
resolver
uniprot_entry
B7Z998_HUMAN
resolver
uniprot_entry
PTPRR_HUMAN
resolver
uniprot_sec
B2R5Z7
resolver
uniprot_sec
B7Z3J1
resolver
uniprot_sec
F5GXR7
resolver
uniprot_sec
O00342
resolver
uniprot_sec
Q92682
resolver
uniprot_sec
Q9UE65
resolver
amino_acid_sequence
MRRAVCFPALCLLLNLHAAGCFSGNNDHFLAINQKKSGKPVFIYKHSQDIEKSLDIAPQKIYRHSYHSSSEAQVSKRHQIVNSAFPRPAYDPSLNLLAMDGQDLEVENLPIPAANVIVVTLQMDVNKLNITLLRIFRQGVAAALGLLPQQVHINRLIGKKNSIELFVSPINRKTGISDALPSEEVLRSLNINVLHQSLSQFGITEVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
73834
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
protein_family
Receptor class 7 subfamily
uniprot
proteins
pubmed
10705342
uniprot
proteins
pubmed
11147789
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16441242
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
25326458
uniprot
proteins
pubmed
7557444
uniprot
proteins
sequence_length
657
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:25326458}.; SUBCELLULAR LOCATION: [Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform Delta]: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.; SUBCELLULAR LOCATION: [Isoform Gamma]: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.
uniprot
proteins
transmembrane_region
TRANSMEM 228..248; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins