Ppp1r1a
entrez
58200
canonical
uniprot
Q9ERT9
canonical
ensembl
ENSMUSG00000022490
resolver
ensp
ENSMUSP00000023133
resolver
enst
ENSMUST00000023133
resolver
genesymbol
Ppp1r1a
resolver
uniprot_entry
PPR1A_MOUSE
resolver
amino_acid_sequence
MEPDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNSLLKSTLSMSPRQRKKMTRTTPTMKELQTMVEHHLGQQKQGEEPEGATESTGNQESCPPGIPDTGSASRPDTPGTAQKSAESNPKTQEQCGVEPRTEDSSAHMLPLDSQGASLV
uniprot
proteins
function
FUNCTION: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
uniprot
proteins
mass_dalton
18718
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Thr-35 is required for activity. {ECO:0000250}.
uniprot
proteins
protein_family
Protein phosphatase inhibitor 1 family
uniprot
proteins
pubmed
10960791
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
171
uniprot
proteins