Cdc42se2
entrez
72729
canonical
uniprot
Q8BGH7
canonical
ensembl
ENSMUSG00000052298
resolver
ensp
ENSMUSP00000070725
resolver
ensp
ENSMUSP00000198026
resolver
ensp
ENSMUSP00000198047
resolver
enst
ENSMUST00000064104
resolver
genesymbol
Cdc42se2
resolver
uniprot
Q3UKN9
resolver
uniprot_entry
C42S2_MOUSE
resolver
uniprot_sec
Q3UKN9
resolver
amino_acid_sequence
MSEFWLCFNCCIAEQPQPKRRRRIDRSMIGEPTNFVHTAHVGSGDLFSGMNSVSSIQNQMQSKGGYGGGMPANVQMQLVDTKAG
uniprot
proteins
function
FUNCTION: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
9223
uniprot
proteins
protein_family
CDC42SE/SPEC family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15840583
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
84
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Cell projection, phagocytic cup {ECO:0000250}. Note=Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages. {ECO:0000250}.
uniprot
proteins