Ctsd
entrez
13033
canonical
uniprot
P18242
canonical
ensembl
ENSMUSG00000007891
resolver
ensp
ENSMUSP00000121203
resolver
enst
ENSMUST00000151120
resolver
genesymbol
Ctsd
resolver
uniprot
Q3UCD9
resolver
uniprot_entry
CATD_MOUSE
resolver
uniprot_entry
Q3UCD9_MOUSE
resolver
amino_acid_sequence
MKTPGVLLLILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVGFANAVVL
uniprot
proteins
ec_number
3.4.23.5
uniprot
proteins
function
FUNCTION: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. {ECO:0000250|UniProtKB:P07339}.
uniprot
proteins
mass_dalton
44954
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:P07339, ECO:0000269|PubMed:16170054}.; PTM: Undergoes proteolytic cleavage and activation by ADAM30. {ECO:0000250|UniProtKB:P07339}.
uniprot
proteins
protein_family
Peptidase A1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16170054
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2263503
uniprot
proteins
pubmed
2374732
uniprot
proteins
pubmed
28453791
uniprot
proteins
pubmed
8011168
uniprot
proteins
sequence_length
410
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome. Melanosome {ECO:0000250}. Secreted, extracellular space {ECO:0000250}.
uniprot
proteins