Slco3a1
entrez
140915
canonical
uniprot
Q99N02
canonical
ensembl
ENSRNOG00000032798
resolver
ensp
ENSRNOP00000074908
resolver
enst
ENSRNOT00000082564
resolver
genesymbol
Slco3a1
resolver
genesymbol_syn
Oatp3a1
resolver
genesymbol_syn
Oatpd
resolver
genesymbol_syn
Pgt2
resolver
genesymbol_syn
Slc21a11
resolver
uniprot
A0A0G2K992
resolver
uniprot_entry
A0A0G2K992_RAT
resolver
uniprot_entry
SO3A1_RAT
resolver
amino_acid_sequence
MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCATNGSSSDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPGMESEQAMLPEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIVLAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTVPVAGVTVRYGNNSARGSPLDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTGCACLTTVPPENATVVPGKCPSPGCQEAFLTFLCVMCVCSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSEFLASTLTLDNLGRDPVPAHQTHRTKFIYNLEDHEWCENMESVL
uniprot
proteins
function
FUNCTION: Putative organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormone L-thyroxine, prostanoids such as prostaglandin E1 and E2, bile acids such as taurocholate, glycolate and glycochenodeoxycholate and peptide hormones such as L-arginine vasopressin, likely operating in a tissue-specific manner (By similarity) (PubMed:14631946). The transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable). Mediates transport of tryptophan, phenyalanine, tyrosine, and steroid hormone precursors dehydroepiandrosterone 3-sulfate and estrone 3-sulfate (By similarity). {ECO:0000250|UniProtKB:Q9UIG8, ECO:0000269|PubMed:14631946, ECO:0000305}.
uniprot
proteins
mass_dalton
76825
uniprot
proteins
protein_family
Organo anion transporter (TC 2.A.60) family
uniprot
proteins
pubmed
14631946
uniprot
proteins
pubmed
16971491
uniprot
proteins
sequence_length
710
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000250|UniProtKB:Q9UIG8}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000250|UniProtKB:Q9UIG8}; Multi-pass membrane protein {ECO:0000255}. Basal cell membrane {ECO:0000250|UniProtKB:Q9UIG8}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 41..60; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 80..100; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 107..131; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 175..203; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 223..243; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 262..286; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 345..366; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 387..410; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 415..438; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 540..562; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 572..597; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 631..648; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins