Cyp27b1
entrez
114700
canonical
uniprot
O35132
canonical
ensembl
ENSRNOG00000046214
resolver
ensembl
ENSRNOG00065016075
resolver
ensp
ENSRNOP00000064023
resolver
ensp
ENSRNOP00065020967
resolver
enst
ENSRNOT00065026720
resolver
genesymbol
Cyp27b1
resolver
genesymbol_syn
Cyp27b
resolver
uniprot
O35076
resolver
uniprot_entry
CP27B_RAT
resolver
uniprot_sec
O35076
resolver
amino_acid_sequence
MTQAVKLASRVFHRVQLPSQLGSDSVLRSLSDIPGPSTPSFLAELFCKGGLSRLHELQVHGAARYGPIWSGSFGTLRTVYVADPALVEQLLRQESHCPERCSFSSWSEHRRRHQRACGLLTADGEEWQRLRSLLAPLLLRPQAAAGYAGTLDSVVSDLVRRLRRQRGRGSGLPDLVLDVAGEFYKFGLEGIGAVLLGSRLGCLEAEVPPDTETFIEAVGSVFVSTLLTMAMPSWLHRLIPGPWARLCRDWDQMFAFAQKHVEQREGEAAVRNQGKPEEDLPTGHHLTHFLFREKVSVQSIVGNVTELLLAGVDTVSNTLSWALYELSRHPEVQSALHSEITGAVNPGSYAHLQATALSQLPLLKAVIKEVLRLYPVVPGNSRVPDRDICVGNYVIPQDTLVSLCHYATSRDPAQFREPNSFNPARWLGEGPAPHPFASLPFGFGKRSCIGRRLAELELQMALAQILTHFEVLPEPGALPVKPMTRTVLVPERSIHLQFVDR
uniprot
proteins
ec_number
1.14.15.18
uniprot
proteins
function
FUNCTION: Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D3) to 1-alpha,25-dihydroxyvitamin D3 (1alpha,25(OH)(2)D3), and of 24,25-dihydroxyvitamin D3 (24,25(OH)(2)D3) to 1-alpha,24,25-trihydroxyvitamin D3 (1alpha,24,25(OH)(3)D3). Is also active with 25-hydroxy-24-oxo-vitamin D3. Plays an important role in normal bone growth, calcium metabolism, and tissue differentiation. {ECO:0000250|UniProtKB:O35084}.
uniprot
proteins
mass_dalton
55369
uniprot
proteins
pathway_participation
PATHWAY: Hormone biosynthesis; cholecalciferol biosynthesis.
uniprot
proteins
protein_family
Cytochrome P450 family
uniprot
proteins
pubmed
9333115
uniprot
proteins
pubmed
9371776
uniprot
proteins
sequence_length
501
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane.
uniprot
proteins