Asip
entrez
24152
canonical
uniprot
Q99JA2
canonical
genesymbol
Asip
resolver
genesymbol_syn
A
resolver
uniprot_entry
ASIP_RAT
resolver
amino_acid_sequence
MDVTRLLLATLVGFLCFLTVHSHLVFEETLGDDRSLKSNSSINSLDFSSVSIVALNKKSKKISRKEAEKRKRSSKKKASIKKVARPPPPSPCVATRDSCKPPAPACCNPCASCQCRFFGSACTCRVLNPNC
uniprot
proteins
function
FUNCTION: Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). {ECO:0000269|PubMed:11353396}.
uniprot
proteins
mass_dalton
14276
uniprot
proteins
pubmed
11353396
uniprot
proteins
sequence_length
131
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q03288}.
uniprot
proteins