Arf5
entrez
11844
canonical
uniprot
P84084
canonical
ensembl
ENSMUSG00000020440
resolver
ensp
ENSMUSP00000020717
resolver
enst
ENSMUST00000020717
resolver
genesymbol
Arf5
resolver
uniprot
A2RTC5
resolver
uniprot
P26437
resolver
uniprot_entry
ARF5_MOUSE
resolver
uniprot_sec
A2RTC5
resolver
uniprot_sec
P26437
resolver
amino_acid_sequence
MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
uniprot
proteins
function
FUNCTION: GTP-binding protein involved in protein trafficking. Contributes to vesicle budding and uncoating at the Golgi apparatus. Regulates mTORC1 activity at the plasma membrane by promoting its recruitment to membrane ruffles, facilitating activation via the PI3K/Akt signaling pathway. Acts as an early responder to lysosomal damage and participates in lysosomal quality control pathways. {ECO:0000250|UniProtKB:P84085}.
uniprot
proteins
mass_dalton
20530
uniprot
proteins
protein_family
Arf family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
11950392
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8947846
uniprot
proteins
sequence_length
180
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P84085}. Golgi apparatus {ECO:0000250|UniProtKB:P84085}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P84085}. Lysosome membrane {ECO:0000250|UniProtKB:P84085}; Lipid-anchor {ECO:0000250|UniProtKB:P84085}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:11950392}; Lipid-anchor {ECO:0000269|PubMed:11950392}.
uniprot
proteins