Phactr1
entrez
306844
canonical
uniprot
P62024
canonical
ensembl
ENSRNOG00000014264
resolver
ensembl
ENSRNOG00055007606
resolver
ensembl
ENSRNOG00060009910
resolver
ensembl
ENSRNOG00065008419
resolver
ensp
ENSRNOP00000043053
resolver
ensp
ENSRNOP00000077447
resolver
ensp
ENSRNOP00000078261
resolver
ensp
ENSRNOP00000097958
resolver
ensp
ENSRNOP00055010157
resolver
ensp
ENSRNOP00060013101
resolver
ensp
ENSRNOP00065009876
resolver
enst
ENSRNOT00000046523
resolver
enst
ENSRNOT00000106668
resolver
enst
ENSRNOT00000107421
resolver
enst
ENSRNOT00000110352
resolver
enst
ENSRNOT00055012740
resolver
enst
ENSRNOT00060016756
resolver
enst
ENSRNOT00065013348
resolver
genesymbol
Phactr1
resolver
genesymbol_syn
AABR07027306.1
resolver
uniprot
A0A8I5XW51
resolver
uniprot
A0A8I5ZKJ8
resolver
uniprot
A0A8I6ATP4
resolver
uniprot
F1LNB2
resolver
uniprot
Q4KMC2
resolver
uniprot_entry
A0A8I5XW51_RAT
resolver
uniprot_entry
A0A8I5ZKJ8_RAT
resolver
uniprot_entry
A0A8I6ATP4_RAT
resolver
uniprot_entry
F1LNB2_RAT
resolver
uniprot_entry
PHAR1_RAT
resolver
uniprot_sec
Q4KMC2
resolver
amino_acid_sequence
MDYPKMDYFLDVESAHRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDDIDRRPIRRVRSKSDTPYLAEARISFNLGAAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELSISNEDDSLTNGQSLSSSQLSLPALSEMEPVPMPRDPCSYEVLQASDIMDGPDPGAPVKLPCLPVKLSPPLPPKKVLICMPVGGPELSLASYAAQKSSQQAVAQHHHTVLPSQMQHQLQYGSHGQHLPSSTGTLPMHPSGCRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSSDGVTKAGPLGLPEIRQVPTVVIECDDNKENVPHEPDYEDSSCLYAREEEEEEEDEDDDASLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP
uniprot
proteins
function
FUNCTION: Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity (By similarity). Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity). {ECO:0000250|UniProtKB:Q2M3X8}.
uniprot
proteins
mass_dalton
66216
uniprot
proteins
mutagenesis
MUTAGEN 576; /note="R->A: No effect on PPP1CA-binding."; /evidence="ECO:0000269|PubMed:15107502"; MUTAGEN 577; /note="F->A: Strongly reduces PPP1CA-binding."; /evidence="ECO:0000269|PubMed:15107502"; MUTAGEN 578; /note="H->A: Reduces PPP1CA-binding."; /evidence="ECO:0000269|PubMed:15107502"; MUTAGEN 579; /note="R->A: No effect on PPP1CA-binding."; /evidence="ECO:0000269|PubMed:15107502"; MUTAGEN 580; /note="P->A: No effect on PPP1CA-binding."; /evidence="ECO:0000269|PubMed:15107502
uniprot
proteins
protein_family
Phosphatase and actin regulator family
uniprot
proteins
pubmed
15107502
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
580
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15107502}. Synapse {ECO:0000269|PubMed:15107502}. Nucleus {ECO:0000250}. Note=Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity). Enriched at synapses. {ECO:0000250}.
uniprot
proteins