Med22
entrez
499762
canonical
uniprot
A0JPN6
canonical
ensembl
ENSRNOG00000005059
resolver
ensembl
ENSRNOG00055005951
resolver
ensembl
ENSRNOG00060027551
resolver
ensembl
ENSRNOG00065023403
resolver
ensp
ENSRNOP00000006720
resolver
genesymbol
Med22
resolver
genesymbol_syn
Surf5
resolver
uniprot_entry
MED22_RAT
resolver
amino_acid_sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLITLRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDTDSADGLSAPLLASPETGAGPLQSAAPVHSHGGGPGPTEHT
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
22312
uniprot
proteins
protein_family
Mediator complex subunit 22 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
200
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins