Chst5
entrez
56773
canonical
uniprot
Q9QUP4
canonical
ensembl
ENSMUSG00000031952
resolver
ensp
ENSMUSP00000034430
resolver
enst
ENSMUST00000034430
resolver
genesymbol
Chst5
resolver
genesymbol_syn
Gst4
resolver
uniprot_entry
CHST5_MOUSE
resolver
amino_acid_sequence
MRLPRFSSTVMLSLLMVQTGILVFLVSRQVPSSPAGLGERVHVLVLSSWRSGSSFVGQLFSQHPDVFYLMEPAWHVWDTLSQGSAPALHMAVRDLIRSVFLCDMDVFDAYLPWRRNISDLFQWAVSRALCSPPVCEAFARGNISSEEVCKPLCATRPFGLAQEACSSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREQTAKALARDNGIVLGTNGTWVEADPRLRVVNEVCRSHVRIAEAALHKPPPFLQDRYRLVRYEDLARDPLTVIRELYAFTGLGLTPQLQTWIHNITHGSGPGARREAFKTTSRDALSVSQAWRHTLPFAKIRRVQELCGGALQLLGYRSVHSELEQRDLSLDLLLPRGMDSFKWASSTEKQPES
uniprot
proteins
ec_number
2.8.2.21
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan (PubMed:12218059, PubMed:30867513). Involved in biosynthesis of keratan sulfate in cornea, with an impact on proteoglycan fibril organization and corneal transparency (PubMed:11278593, PubMed:16938851). Involved in biosynthesis of phosphacan (isoform of PTPRZ), a major keratan sulfate proteoglycan in the developing brain (PubMed:30867513). {ECO:0000269|PubMed:11278593, ECO:0000269|PubMed:12218059, ECO:0000269|PubMed:16938851, ECO:0000269|PubMed:30867513}.
uniprot
proteins
mass_dalton
44537
uniprot
proteins
protein_family
Gal/GlcNAc/GalNAc subfamily
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
10491328
uniprot
proteins
pubmed
11278593
uniprot
proteins
pubmed
12218059
uniprot
proteins
pubmed
16938851
uniprot
proteins
pubmed
30867513
uniprot
proteins
sequence_length
395
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9GZS9}; Single-pass type II membrane protein {ECO:0000250}. Note=Golgi membrane, early secretory pathway. {ECO:0000250|UniProtKB:Q9GZS9}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..26; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins