CD200R1
entrez
131450
canonical
uniprot
Q8TD46
canonical
ensembl
ENSG00000163606
resolver
ensp
ENSP00000311035
resolver
ensp
ENSP00000405733
resolver
ensp
ENSP00000418801
resolver
ensp
ENSP00000418928
resolver
genesymbol
CD200R1
resolver
genesymbol_syn
CD200R
resolver
genesymbol_syn
CRTR2
resolver
genesymbol_syn
MOX2R
resolver
genesymbol_syn
OX2R
resolver
hgnc
HGNC:24235
resolver
uniprot
B3KWZ9
resolver
uniprot
E9PCM9
resolver
uniprot
Q52LJ7
resolver
uniprot
Q6IS95
resolver
uniprot
Q6UW94
resolver
uniprot
Q6WHB8
resolver
uniprot
Q8TD44
resolver
uniprot
Q8TD45
resolver
uniprot
Q8TD52
resolver
uniprot_entry
MO2R1_HUMAN
resolver
uniprot_sec
B3KWZ9
resolver
uniprot_sec
E9PCM9
resolver
uniprot_sec
Q52LJ7
resolver
uniprot_sec
Q6IS95
resolver
uniprot_sec
Q6UW94
resolver
uniprot_sec
Q6WHB8
resolver
uniprot_sec
Q8TD44
resolver
uniprot_sec
Q8TD45
resolver
uniprot_sec
Q8TD52
resolver
amino_acid_sequence
MLCPWRTANLGLLLILTIFLVAEAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATNAVLCCPPIALRNLIIITWEIILRGQPSCTKAYKKETNETKETNCTDERITWVSRPDQNSDLQIRTVAITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAVCKAVAGKPAAHISWIPEGDCATKQEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLPVPGAKKSAKLYIPYIILTIIILTIVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQPYASYTEKNNPLYDTTNKVKASEALQSEVDTDLHTL
uniprot
proteins
function
FUNCTION: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. {ECO:0000269|PubMed:12960329}.
uniprot
proteins
mass_dalton
39041
uniprot
proteins
protein_family
CD200R family
uniprot
proteins
pubmed
12960329
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15274657
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24388216
uniprot
proteins
sequence_length
348
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.; SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
uniprot
proteins
transmembrane_region
TRANSMEM 266..286; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins