Ctsc
entrez
25423
canonical
uniprot
P80067
canonical
ensembl
ENSRNOG00000016496
resolver
ensp
ENSRNOP00000022342
resolver
enst
ENSRNOT00000022342
resolver
genesymbol
Ctsc
resolver
uniprot
P80068
resolver
uniprot_entry
CATC_RAT
resolver
uniprot_sec
P80068
resolver
amino_acid_sequence
MGPWTHSLRAALLLVLLGVCTVSSDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPIPKL
uniprot
proteins
ec_number
3.4.14.1
uniprot
proteins
function
FUNCTION: Thiol protease (PubMed:1740150). Has dipeptidylpeptidase activity (PubMed:1740150). Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate (PubMed:1740150). Can act as both an exopeptidase and endopeptidase (By similarity). Activates serine proteases such as elastase, cathepsin G and granzymes A and B (By similarity). {ECO:0000250|UniProtKB:P53634, ECO:0000269|PubMed:1740150}.
uniprot
proteins
mass_dalton
52235
uniprot
proteins
protein_family
Peptidase C1 family
uniprot
proteins
pubmed
11602245
uniprot
proteins
pubmed
1515062
uniprot
proteins
pubmed
1740150
uniprot
proteins
pubmed
1885565
uniprot
proteins
sequence_length
462
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000269|PubMed:1740150}.
uniprot
proteins