Pde4b
entrez
24626
canonical
uniprot
P14646
canonical
ensembl
ENSRNOG00000005905
resolver
ensp
ENSRNOP00000007738
resolver
ensp
ENSRNOP00000008278
resolver
ensp
ENSRNOP00000084515
resolver
ensp
ENSRNOP00000096704
resolver
enst
ENSRNOT00000007738
resolver
enst
ENSRNOT00000098470
resolver
enst
ENSRNOT00000099065
resolver
genesymbol
Pde4b
resolver
uniprot
A0A8I5ZY41
resolver
uniprot
A0A8I6AT13
resolver
uniprot
A0A8L2Q3F0
resolver
uniprot
Q5RKL0
resolver
uniprot
Q8VD81
resolver
uniprot
Q8VD82
resolver
uniprot_entry
A0A8I5ZY41_RAT
resolver
uniprot_entry
A0A8I6AT13_RAT
resolver
uniprot_entry
A0A8L2Q3F0_RAT
resolver
uniprot_entry
PDE4B_RAT
resolver
uniprot_sec
Q5RKL0
resolver
uniprot_sec
Q8VD81
resolver
uniprot_sec
Q8VD82
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by rolipram. {ECO:0000250|UniProtKB:Q07343}.
uniprot
proteins
amino_acid_sequence
MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQSERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRIVRNNFTLLTNLHGAPNKRSPAASQAPVTRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGPNYFSSTKTLCVIDPENRDSLEETDIDIATEDKSLIDT
uniprot
proteins
ec_number
3.1.4.53
uniprot
proteins
function
FUNCTION: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. {ECO:0000269|PubMed:12441002}.
uniprot
proteins
mass_dalton
83375
uniprot
proteins
pathway_participation
PATHWAY: Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. {ECO:0000305|PubMed:12441002}.
uniprot
proteins
protein_family
Cyclic nucleotide phosphodiesterase family
uniprot
proteins
protein_family
PDE4 subfamily
uniprot
proteins
pubmed
12441002
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1655746
uniprot
proteins
pubmed
19103603
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2542941
uniprot
proteins
pubmed
2546153
uniprot
proteins
pubmed
7958996
uniprot
proteins
pubmed
8276818
uniprot
proteins
pubmed
9371714
uniprot
proteins
sequence_length
736
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm {ECO:0000250|UniProtKB:Q07343}. Cell membrane {ECO:0000250|UniProtKB:Q07343}.
uniprot
proteins