Cacng3
entrez
140724
canonical
uniprot
Q8VHX0
canonical
ensembl
ENSRNOG00000012362
resolver
ensembl
ENSRNOG00055008418
resolver
ensembl
ENSRNOG00060030131
resolver
ensembl
ENSRNOG00065013062
resolver
ensp
ENSRNOP00000016632
resolver
ensp
ENSRNOP00055011429
resolver
ensp
ENSRNOP00060043557
resolver
ensp
ENSRNOP00065016565
resolver
enst
ENSRNOT00000016632
resolver
enst
ENSRNOT00055014238
resolver
enst
ENSRNOT00060052336
resolver
enst
ENSRNOT00065021407
resolver
genesymbol
Cacng3
resolver
uniprot_entry
CCG3_RAT
resolver
amino_acid_sequence
MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHSVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRARSHSELLKKSTFARLPPYRYRFRRRSSSRSTEPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKLTMGTLLNSDRDHAFLQFHNSTPKEFKESLHNNPANRRTTPV
uniprot
proteins
function
FUNCTION: Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. {ECO:0000269|PubMed:17880894, ECO:0000269|PubMed:19234459}.
uniprot
proteins
mass_dalton
35516
uniprot
proteins
protein_family
CACNG subfamily
uniprot
proteins
protein_family
PMP-22/EMP/MP20 family
uniprot
proteins
pubmed
11738816
uniprot
proteins
pubmed
17880894
uniprot
proteins
pubmed
19234459
uniprot
proteins
pubmed
19265014
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
315
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Displays a somatodendritic localization and is excluded from axons in neurons. {ECO:0000250|UniProtKB:Q9JJV5}.
uniprot
proteins
transmembrane_region
TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 135..155; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 181..201; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins