ABHD16B
entrez
140701
canonical
uniprot
Q9H3Z7
canonical
ensembl
ENSG00000183260
resolver
ensp
ENSP00000358932
resolver
enst
ENST00000369916
resolver
genesymbol
ABHD16B
resolver
genesymbol_syn
C20orf135
resolver
hgnc
HGNC:16128
resolver
uniprot_entry
ABHGB_HUMAN
resolver
amino_acid_sequence
MCVICFVKALVRVFKIYLTASYTYPFRGWPVAFRWDDVRAVGRSSSHRALTCAAAAAGVWLLRDETLGGDALGRPPRGARSQAQCLLQQLRELPGQLASYALAHSLGRWLVYPGSVSLMTRALLPLLQQGQERLVERYHGRRAKLVACDGNEIDTMFMDRRQHPGSHVHGPRLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGSSTGVPFPQHDANAMDVVVEYALHRLHFPPAHLVVYGWSVGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHSWKGLVVRTVREHFNLNVAEQLCCYPGPVLLLRRTQDDVVSTSGRLRPLSPGDVEGNRGNELLLRLLEHRYPVVMAREGRAVVTRWLRAGSLAQEAAFYARYRVDEDWCLALLRSYRARCEEELEGEEALGPHGPAFPWLVGQGLSSRRRRRLALFLARKHLKNVEATHFSPLEPEEFQLPWRL
uniprot
proteins
ec_number
3.1.1.111
uniprot
proteins
function
FUNCTION: Hydrolyzes the sn-1 position of glycerophospholipids with high specificity towards phosphatidylserine (PS), PS-PLA1 enzyme (PubMed:36841071). Also hydrolyzes the acyl chain of glycerolipids with a preference for the monoacylglycerol (MAG) 1-acylglycerol, MAG lipase (PubMed:36841071). Plays a regulatory role in cellular lipid homeostasis by modulating genes involved in neutral lipid degradation and in phospholipid synthesis and composition (PubMed:37944658). {ECO:0000269|PubMed:36841071, ECO:0000269|PubMed:37944658}.
uniprot
proteins
mass_dalton
52555
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
ABHD16 family
uniprot
proteins
pubmed
11780052
uniprot
proteins
pubmed
36841071
uniprot
proteins
pubmed
37944658
uniprot
proteins
sequence_length
469
uniprot
proteins