NAA30
entrez
122830
canonical
uniprot
Q147X3
canonical
ensembl
ENSG00000139977
resolver
ensp
ENSP00000452521
resolver
genesymbol
NAA30
resolver
genesymbol_syn
C14orf35
resolver
genesymbol_syn
MAK3
resolver
genesymbol_syn
NAT12
resolver
hgnc
HGNC:19844
resolver
uniprot
B3KS28
resolver
uniprot
Q0IIN2
resolver
uniprot_entry
B3KS28_HUMAN
resolver
uniprot_entry
NAA30_HUMAN
resolver
uniprot_sec
Q0IIN2
resolver
amino_acid_sequence
MAEVPPGPSSLLPPPAPPAPAAVEPRCPFPAGAALACCSEDEEDDEEHEGGGSRSPAGGESATVAAKGHPCLRCPQPPQEQQQLNGLISPELRHLRAAASLKSKVLSVAEVAATTATPDGGPRATATKGAGVHSGERPPHSLSSNARTAVPSPVEAAAASDPAAARNGLAEGTEQEEEEEDEQVRLLSSSLTADCSLRSPSGREVEPGEDRTIRYVRYESELQMPDIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR
uniprot
proteins
ec_number
2.3.1.256
uniprot
proteins
function
FUNCTION: Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex (PubMed:19398576, PubMed:37891180). Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly (PubMed:19398576, PubMed:37891180). N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway (PubMed:37891180). Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate (PubMed:19398576). {ECO:0000269|PubMed:19398576, ECO:0000269|PubMed:37891180}.
uniprot
proteins
mass_dalton
39320
uniprot
proteins
protein_family
Acetyltransferase family
uniprot
proteins
protein_family
MAK3 subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
19398576
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19660095
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25732826
uniprot
proteins
pubmed
37891180
uniprot
proteins
sequence_length
362
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19398576, ECO:0000269|PubMed:25732826}. Nucleus {ECO:0000269|PubMed:25732826}.
uniprot
proteins