SMYD1
entrez
150572
canonical
uniprot
Q8NB12
canonical
ensembl
ENSG00000115593
resolver
ensp
ENSP00000393453
resolver
ensp
ENSP00000407888
resolver
enst
ENST00000419482
resolver
enst
ENST00000444564
resolver
genesymbol
SMYD1
resolver
hgnc
HGNC:20986
resolver
uniprot
A0AV30
resolver
uniprot
A6NE13
resolver
uniprot
E9PHG3
resolver
uniprot_entry
E9PHG3_HUMAN
resolver
uniprot_entry
SMYD1_HUMAN
resolver
uniprot_sec
A0AV30
resolver
uniprot_sec
A6NE13
resolver
amino_acid_sequence
MTIGRMENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKDLRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKDDLFLGVKDNPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRMLSIVSEVLSYLQAFEEASFYARRMVDGYMKLYHPNNAQLGMAVMRAGLTNWHAGNIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQVMAEPSNEPSPALFHKKQ
uniprot
proteins
ec_number
2.1.1.354
uniprot
proteins
function
FUNCTION: Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. {ECO:0000250|UniProtKB:P97443}.
uniprot
proteins
mass_dalton
56617
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19783823
uniprot
proteins
sequence_length
490
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins