Faap20
entrez
67513
canonical
uniprot
Q3UN58
canonical
ensembl
ENSMUSG00000073684
resolver
ensp
ENSMUSP00000101252
resolver
ensp
ENSMUSP00000137116
resolver
genesymbol
Faap20
resolver
uniprot
A2ADD8
resolver
uniprot
Q0VG17
resolver
uniprot_entry
FAP20_MOUSE
resolver
uniprot_sec
A2ADD8
resolver
uniprot_sec
Q0VG17
resolver
amino_acid_sequence
MEEERRLRGRLSRRRPPAGGGPPNCRPWFLSEGSKSEPWAALLRSTVSGTADWTPNRQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEPEGSLGSPTPSLKGCPALNSGRTPSAQECVPVQSPLALLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDVVW
uniprot
proteins
function
FUNCTION: Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
20038
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
186
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q6NZ36}. Chromosome {ECO:0000250|UniProtKB:Q6NZ36}. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8. {ECO:0000250|UniProtKB:Q6NZ36}.
uniprot
proteins