ANKS3
entrez
124401
canonical
uniprot
Q6ZW76
canonical
ensembl
ENSG00000168096
resolver
ensp
ENSP00000304586
resolver
ensp
ENSP00000388270
resolver
ensp
ENSP00000480350
resolver
enst
ENST00000450067
resolver
genesymbol
ANKS3
resolver
genesymbol_syn
KIAA1977
resolver
hgnc
HGNC:29422
resolver
uniprot
B4DWU4
resolver
uniprot
D3DUE2
resolver
uniprot
F6WF08
resolver
uniprot
Q86W77
resolver
uniprot
Q8TF25
resolver
uniprot_entry
ANKS3_HUMAN
resolver
uniprot_entry
F6WF08_HUMAN
resolver
uniprot_entry
Q86W77_HUMAN
resolver
uniprot_sec
B4DWU4
resolver
uniprot_sec
D3DUE2
resolver
uniprot_sec
Q8TF25
resolver
amino_acid_sequence
MSELSDEASEPELLNRSLSMWHGLGTQVSGEELDVPLDLHTAASIGQYEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEIIVQYFLNHGVKVDARDHSGATARMLAKQYGHMKIVALMDTYSPSLPKSLYRSPEKYEDLSSSDESCPAPQRQRPCRKKGVSIHEGPRALARITGIGLGGRAPRPRYEQAPPRGYVTFNSSGENPLEEEGLCCRDVTSPINERDVESSSSSSSREEHAFCANLGPVQSSSSSEGLARAQGLSSEASVESNEDSDHACKSSARKQAKSYMKTKNPDSQWPPRAATDREGFLAESSPQTQRAPYSGPQDLAALLEQIGCLKYLQVFEEQDVDLRIFLTLTESDLKEIGITLFGPKRKMTSAIARWHSSARPPGDALELAYADRLEAEMQELAIQLHKRCEEVEATRGQVCQEQELRAVVESCLLEQDRAREDLQARLRETWALARDAALVLDQLRACQAELSSRVRQDQPPGAATLGLAVPPADSKGWQASLQAMSLPELSGALEDRVREMGQALCLVTQSLEKLQVLNGKKWRET
uniprot
proteins
function
FUNCTION: May be involved in vasopressin signaling in the kidney. {ECO:0000250|UniProtKB:Q9CZK6}.
uniprot
proteins
mass_dalton
72038
uniprot
proteins
mutagenesis
MUTAGEN 450; /note="D->K: Decreased homooligomerization. No effect on interaction with ANKS6."; /evidence="ECO:0000269|PubMed:24998259"; MUTAGEN 455; /note="I->E: Decreased homooligomerization. No effect on interaction with ANKS6."; /evidence="ECO:0000269|PubMed:24998259"; MUTAGEN 466; /note="E->K: Decreased homooligomerization. No effect on interaction with ANKS6."; /evidence="ECO:0000269|PubMed:24998259"; MUTAGEN 471; /note="L->E: Decreased homooligomerization. Decreased interaction with ANKS6."; /evidence="ECO:0000269|PubMed:24998259"; MUTAGEN 472; /note="F->E: Decreased homooligomerization. Decreased interaction with ANKS6."; /evidence="ECO:0000269|PubMed:24998259"; MUTAGEN 477; /note="K->E: Decreased homooligomerization. Decreased interaction with ANKS6."; /evidence="ECO:0000269|PubMed:24998259
uniprot
proteins
post_translational_modification
PTM: Hydroxylated at Asn-96, most probably by HIF1AN. {ECO:0000250|UniProtKB:Q9CZK6}.; PTM: Phosphorylations at Ser-5, Ser-225, Thr-319, Ser-320, Ser-368 and Ser-371 occur in a NEK7-dependent manner. {ECO:0000250|UniProtKB:Q9CZK6}.; PTM: Polyubiquitinated. {ECO:0000250|UniProtKB:Q9CZK6}.
uniprot
proteins
pubmed
11853319
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
24998259
uniprot
proteins
pubmed
26188091
uniprot
proteins
sequence_length
656
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000250|UniProtKB:Q9CZK6}. Cytoplasm {ECO:0000250|UniProtKB:Q9CZK6}.
uniprot
proteins