Mthfd2l
entrez
305248
canonical
uniprot
D3ZUA0
canonical
ensembl
ENSRNOG00000021347
resolver
ensembl
ENSRNOG00055006399
resolver
ensembl
ENSRNOG00060018107
resolver
ensembl
ENSRNOG00065017090
resolver
ensp
ENSRNOP00000044342
resolver
genesymbol
Mthfd2l
resolver
uniprot_entry
MTD2L_RAT
resolver
amino_acid_sequence
MATRARGLSLLRGRLGRGPARAPGVAERAWRGFGSSSRRHEAVIISGTEMAKQIRRELQQGVESWLALGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELIVKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRAGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRHTPREQLKAHTQLAEIIIVAAGIPGLITADMVREGATVIDVGINYVQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNITY
uniprot
proteins
ec_number
1.5.1.15
uniprot
proteins
ec_number
1.5.1.5
uniprot
proteins
ec_number
3.5.4.9
uniprot
proteins
function
FUNCTION: [Isoform 1]: Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. {ECO:0000269|PubMed:21163947, ECO:0000269|PubMed:24733394}.; FUNCTION: [Isoform 2]: Has no NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase activity. {ECO:0000269|PubMed:24733394}.
uniprot
proteins
mass_dalton
36426
uniprot
proteins
pathway_participation
PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion. {ECO:0000269|PubMed:24733394}.
uniprot
proteins
protein_family
Tetrahydrofolate dehydrogenase/cyclohydrolase family
uniprot
proteins
pubmed
21163947
uniprot
proteins
pubmed
24733394
uniprot
proteins
sequence_length
338
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:21163947}; Peripheral membrane protein {ECO:0000269|PubMed:21163947}; Matrix side {ECO:0000269|PubMed:21163947}.
uniprot
proteins