Ntmt2
entrez
289167
canonical
uniprot
D3ZVR1
canonical
ensembl
ENSRNOG00000025415
resolver
ensembl
ENSRNOG00055017569
resolver
ensembl
ENSRNOG00060009056
resolver
ensembl
ENSRNOG00065020481
resolver
ensp
ENSRNOP00000068028
resolver
ensp
ENSRNOP00055023886
resolver
ensp
ENSRNOP00060011821
resolver
ensp
ENSRNOP00065027767
resolver
enst
ENSRNOT00000076404
resolver
enst
ENSRNOT00055029725
resolver
enst
ENSRNOT00060015198
resolver
enst
ENSRNOT00065034621
resolver
genesymbol
Ntmt2
resolver
genesymbol_syn
Mettl11b
resolver
uniprot_entry
NTM1B_RAT
resolver
amino_acid_sequence
MAHLGAHFAFRSRWQKTDDELCRHSMSFILHKAIRNDFFQSYLYLLEKIPLVKLYALTSQVIDGEMQFYARAKLFYQEVPATEEGMMGNFIELSNPDIQASREFLRKFVGGPGRAGTGCALDCGSGIGRVSKHVLLPVFSSVELVDMMESFLLEAQSYLQVNENKVESYHCYSLQEFTPHLGRYDVIWIQWVSGYLTDKDLLAFLSRCRDGLKENGVIILKDNVAREGCIFDLSDSSVTRDMDILRSLIRKSGLVVLGQEKQEGFPEQCVPVWMFALHSDRHS
uniprot
proteins
ec_number
2.1.1.299
uniprot
proteins
function
FUNCTION: Alpha N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes monomethylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and Pro in the Pro-Pro-Lys motif. Predominantly functions as a mono-methyltransferase but is also able to di-/tri-methylate the GPKRIA peptide and di-methylate the PPKRIA peptide (in vitro). May activate NTMT1 by priming its substrates for trimethylation. {ECO:0000250|UniProtKB:Q5VVY1}.
uniprot
proteins
mass_dalton
32312
uniprot
proteins
protein_family
Methyltransferase superfamily
uniprot
proteins
protein_family
NTM1 family
uniprot
proteins
sequence_length
283
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q5VVY1}.
uniprot
proteins