SLC27A6
entrez
28965
canonical
uniprot
Q9Y2P4
canonical
ensembl
ENSG00000113396
resolver
ensp
ENSP00000262462
resolver
ensp
ENSP00000378684
resolver
ensp
ENSP00000421024
resolver
ensp
ENSP00000571497
resolver
ensp
ENSP00000571498
resolver
ensp
ENSP00000628239
resolver
enst
ENST00000262462
resolver
enst
ENST00000395266
resolver
enst
ENST00000506176
resolver
enst
ENST00000901438
resolver
enst
ENST00000901439
resolver
enst
ENST00000958180
resolver
genesymbol
SLC27A6
resolver
genesymbol_syn
ACSVL2
resolver
genesymbol_syn
FACVL2
resolver
genesymbol_syn
FATP6
resolver
hgnc
HGNC:11000
resolver
uniprot
B2R8P6
resolver
uniprot
Q6IAM5
resolver
uniprot
Q7Z6E6
resolver
uniprot
Q86YF6
resolver
uniprot_entry
B2R8P6_HUMAN
resolver
uniprot_entry
S27A6_HUMAN
resolver
uniprot_sec
Q6IAM5
resolver
uniprot_sec
Q7Z6E6
resolver
uniprot_sec
Q86YF6
resolver
amino_acid_sequence
MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL
uniprot
proteins
ec_number
6.2.1.-
uniprot
proteins
ec_number
6.2.1.15
uniprot
proteins
ec_number
6.2.1.3
uniprot
proteins
function
FUNCTION: Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (PubMed:12556534). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (By similarity). Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation such as the heart (PubMed:12556534). {ECO:0000250|UniProtKB:E9Q9W4, ECO:0000269|PubMed:12556534}.
uniprot
proteins
mass_dalton
70112
uniprot
proteins
protein_family
ATP-dependent AMP-binding enzyme family
uniprot
proteins
pubmed
12556534
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
619
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane, sarcolemma {ECO:0000305|PubMed:12556534}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:E9Q9W4}; Multi-pass membrane protein {ECO:0000255}. Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36. {ECO:0000305|PubMed:12556534}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 119..139; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins