Rab3c
entrez
171058
canonical
uniprot
P62824
canonical
ensembl
ENSRNOG00000011623
resolver
ensembl
ENSRNOG00055011684
resolver
ensembl
ENSRNOG00060003825
resolver
ensembl
ENSRNOG00065019722
resolver
ensp
ENSRNOP00000015871
resolver
ensp
ENSRNOP00000096986
resolver
ensp
ENSRNOP00000104946
resolver
ensp
ENSRNOP00055016035
resolver
ensp
ENSRNOP00055016037
resolver
ensp
ENSRNOP00060004808
resolver
ensp
ENSRNOP00060004812
resolver
ensp
ENSRNOP00065026632
resolver
ensp
ENSRNOP00065026636
resolver
enst
ENSRNOT00000015871
resolver
enst
ENSRNOT00000116600
resolver
enst
ENSRNOT00000170596
resolver
enst
ENSRNOT00055019886
resolver
enst
ENSRNOT00055019889
resolver
enst
ENSRNOT00060006420
resolver
enst
ENSRNOT00060006425
resolver
enst
ENSRNOT00065033273
resolver
enst
ENSRNOT00065033279
resolver
genesymbol
Rab3c
resolver
uniprot
A0A8L2Q7P7
resolver
uniprot
Q62858
resolver
uniprot
Q62974
resolver
uniprot
Q63482
resolver
uniprot
Q9CXQ1
resolver
uniprot_entry
A0A8L2Q7P7_RAT
resolver
uniprot_entry
RAB3C_RAT
resolver
uniprot_sec
Q62858
resolver
uniprot_sec
Q62974
resolver
uniprot_sec
Q63482
resolver
uniprot_sec
Q9CXQ1
resolver
activity_regulation
ACTIVITY REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. Regulated by GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity. Inhibited by GDP dissociation inhibitors (GDIs) which prevent Rab-GDP dissociation. {ECO:0000250|UniProtKB:P20336}.
uniprot
proteins
amino_acid_sequence
MRHEAPMQMASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQSTRLKETPPPPQPNCGC
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. {ECO:0000250|UniProtKB:P10949}.
uniprot
proteins
mass_dalton
25872
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM and RAB GDP dissociation inhibitor GDI2. {ECO:0000250|UniProtKB:Q96E17}.
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
8841986
uniprot
proteins
pubmed
8885988
uniprot
proteins
pubmed
9252191
uniprot
proteins
sequence_length
227
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins