HPX
entrez
3263
canonical
uniprot
P02790
canonical
ensembl
ENSG00000110169
resolver
ensp
ENSP00000265983
resolver
enst
ENST00000265983
resolver
genesymbol
HPX
resolver
hgnc
HGNC:5171
resolver
uniprot
B2R957
resolver
uniprot
Q9BS19
resolver
uniprot_entry
HEMO_HUMAN
resolver
uniprot_entry
Q9BS19_HUMAN
resolver
uniprot_sec
B2R957
resolver
amino_acid_sequence
MARVLGAPVALGLWSLCWSLAIATPLPPTSAHGNVAEGETKPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWDRELISERWKNFPSPVDAAFRQGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAEGVLFFQGDREWFWDLATGTMKERSWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGEVPPRYPRDVRDYFMPCPGRGHGHRNGTGHGNSTHHGPEYMRCSPHLVLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQWPQGPSAVDAAFSWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKRLEKEVGTPHGIILDSVDAAFICPGSSRLHIMAGRRLWWLDLKSGAQATWTELPWPHEKVDGALCMEKSLGPNSCSANGPGLYLIHGPNLYCYSDVEKLNAAKALPQPQNVTSLLGCTH
uniprot
proteins
function
FUNCTION: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
uniprot
proteins
mass_dalton
51676
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29. {ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:16740002, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:23234360, ECO:0000269|PubMed:6371807}.
uniprot
proteins
protein_family
Hemopexin family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14760718
uniprot
proteins
pubmed
15084671
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16740002
uniprot
proteins
pubmed
18211098
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
19838169
uniprot
proteins
pubmed
20610401
uniprot
proteins
pubmed
23234360
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
2842511
uniprot
proteins
pubmed
2989777
uniprot
proteins
pubmed
3220477
uniprot
proteins
pubmed
3855550
uniprot
proteins
pubmed
6371807
uniprot
proteins
pubmed
6510521
uniprot
proteins
sequence_length
462
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins