Fstl3
entrez
114031
canonical
uniprot
Q99PW7
canonical
ensembl
ENSRNOG00000009311
resolver
ensembl
ENSRNOG00055032847
resolver
ensembl
ENSRNOG00060026817
resolver
ensembl
ENSRNOG00065020413
resolver
ensp
ENSRNOP00000012578
resolver
ensp
ENSRNOP00055046916
resolver
ensp
ENSRNOP00060038606
resolver
ensp
ENSRNOP00065027648
resolver
enst
ENSRNOT00055056815
resolver
enst
ENSRNOT00060046448
resolver
enst
ENSRNOT00065034502
resolver
genesymbol
Fstl3
resolver
genesymbol_syn
Flrg
resolver
uniprot
Q54A93
resolver
uniprot_entry
FSTL3_RAT
resolver
uniprot_sec
Q54A93
resolver
amino_acid_sequence
MRPGALWPLLWGALVWAVGSVGAVMGSGDSVPGGVCWLQQGKEATCSLVLKTQVSREECCASGNINTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPHCECVSNCEGVPAGFQVCGSDGATYRDECELRTARCRGHPDLRVMYRGRCQKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPPNPGQELCGNNNVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVPAEEEENFV
uniprot
proteins
function
FUNCTION: The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such as activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
27109
uniprot
proteins
pubmed
12493714
uniprot
proteins
sequence_length
256
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins