GPR137
entrez
56834
canonical
uniprot
Q96N19
canonical
ensembl
ENSG00000173264
resolver
ensp
ENSP00000321698
resolver
ensp
ENSP00000366931
resolver
ensp
ENSP00000415698
resolver
ensp
ENSP00000524038
resolver
ensp
ENSP00000524040
resolver
ensp
ENSP00000524043
resolver
ensp
ENSP00000524046
resolver
ensp
ENSP00000608944
resolver
ensp
ENSP00000624838
resolver
ensp
ENSP00000649515
resolver
ensp
ENSP00000769392
resolver
ensp
ENSP00000769393
resolver
genesymbol
GPR137
resolver
genesymbol_syn
C11orf4
resolver
genesymbol_syn
GPR137A
resolver
genesymbol_syn
TM7SF1L1
resolver
hgnc
HGNC:24300
resolver
uniprot
B4DTG7
resolver
uniprot
B7Z7M1
resolver
uniprot
Q4G0Y9
resolver
uniprot
Q8N4K6
resolver
uniprot_entry
G137A_HUMAN
resolver
uniprot_sec
B4DTG7
resolver
uniprot_sec
B7Z7M1
resolver
uniprot_sec
Q4G0Y9
resolver
uniprot_sec
Q8N4K6
resolver
amino_acid_sequence
MESNLSGLVPAAGLVPALPPAVTLGLTAAYTTLYALLFFSVYAQLWLVLLYGHKRLSYQTVFLALCLLWAALRTTLFSFYFRDTPRANRLGPLPFWLLYCCPVCLQFFTLTLMNLYFAQVVFKAKVKRRPEMSRGLLAVRGAFVGASLLFLLVNVLCAVLSHRRRAQPWALLLVRVLVSDSLFVICALSLAACLCLVARRAPSTSIYLEAKGTSVCQAAAMGGAMVLLYASRACYNLTALALAPQSRLDTFDYDWYNVSDQADLVNDLGNKGYLVFGLILFVWELLPTTLLVGFFRVHRPPQDLSTSHILNGQVFASRSYFFDRAGHCEDEGCSWEHSRGESTRCQDQAATTTVSTPPHRRDPPPSPTEYPGPSPPHPRPLCQVCLPLLAQDPGGRGYPLLWPAPCCSCHSELVPSP
uniprot
proteins
function
FUNCTION: Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes (PubMed:31036939). May play a role in autophagy (PubMed:31036939). {ECO:0000269|PubMed:31036939}.; FUNCTION: May activate Wnt/beta-catenin signaling to modulate epithelial cell function. {ECO:0000250|UniProtKB:Q80ZU9}.
uniprot
proteins
mass_dalton
46059
uniprot
proteins
protein_family
GPR137 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
31036939
uniprot
proteins
sequence_length
417
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000269|PubMed:31036939}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 32..52; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 61..81; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 90..110; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 176..196; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 219..241; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 275..295; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins