Q8NGC2
uniprot
Q8NGC2
canonical
activity_regulation
ACTIVITY REGULATION: Copper binding enhances receptor activity in response to odorant binding. {ECO:0000250|UniProtKB:Q7TQQ0}.
uniprot
proteins
amino_acid_sequence
MDSLNQTRVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTPLHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTSYMVILVSLRKHSAEGRQKALSTCSAHFMVVALFFGPCIFIYTRPDTSFSIDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT
uniprot
proteins
function
FUNCTION: Olfactory receptor that is activated by the binding of organosulfur odorants with thioether groups such as (methylthio)methanethiol (MTMT) and bis(methylthiomethyl) disulfide (By similarity). Also binds odorants cis-cyclooctene and tert-butyl mercaptan (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). {ECO:0000250|UniProtKB:Q7TQQ0}.
uniprot
proteins
mass_dalton
35466
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12213199
uniprot
proteins
pubmed
14983052
uniprot
proteins
sequence_length
313
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7TQQ0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q7TQQ0}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..49; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 58..79; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 101..120; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 140..158; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 196..219; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 236..258; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 270..289; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins