Toxin-antitoxin system
uniprot_keyword
KW-1277
canonical
name
Toxin-antitoxin system
uniprot
synonym
Toxin-antitoxin module
uniprot
definition
Bacterial, archaeal or viral protein belonging to a toxin-antitoxin (TA) system. Toxin protein expression is poisonous to the cell and is counteracted by its co-expressed, short-lived "antidote" antitoxin. Antitoxins can be protein (type II, IV, V, VI) or RNA (type I, III) and act directly or indirectly on the toxin protein or transcript. Genes for the 2 components are closely linked; in many type II TA systems the toxin-antitoxin complex regulates transcription of its operon. Toxins belong to recognizable protein families, antitoxins usually do not. Orphan toxin genes are occasionally found in complete genomes.
uniprot
keywords
is_obsolete
false
uniprot
keywords
ontology_id
uniprot_keywords
uniprot
keywords