RPS20
entrez
6224
canonical
uniprot
P60866
canonical
ensembl
ENSG00000008988
resolver
ensp
ENSP00000009589
resolver
ensp
ENSP00000429374
resolver
genesymbol
RPS20
resolver
hgnc
HGNC:10405
resolver
uniprot
B2R4F4
resolver
uniprot
B4DW28
resolver
uniprot
P17075
resolver
uniprot
Q5M8S9
resolver
uniprot_entry
RS20_HUMAN
resolver
uniprot_sec
B2R4F4
resolver
uniprot_sec
B4DW28
resolver
uniprot_sec
P17075
resolver
uniprot_sec
Q5M8S9
resolver
amino_acid_sequence
MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA
uniprot
proteins
function
FUNCTION: Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). {ECO:0000269|PubMed:23636399}.
uniprot
proteins
mass_dalton
13373
uniprot
proteins
mutagenesis
MUTAGEN 4; /note="K->R: Enhanced readthrough on the poly(A)-stall sequences; when associated with R-8."; /evidence="ECO:0000269|PubMed:28065601, ECO:0000269|PubMed:28132843, ECO:0000269|PubMed:32011234, ECO:0000269|PubMed:36302773"; MUTAGEN 8; /note="K->R: Enhanced readthrough on the poly(A)-stall sequences; when associated with R-4."; /evidence="ECO:0000269|PubMed:28065601, ECO:0000269|PubMed:28132843, ECO:0000269|PubMed:32011234, ECO:0000269|PubMed:36302773
uniprot
proteins
post_translational_modification
PTM: Polyubiquitinated by ZNF598 via 'Lys-63'-linked ubiquitin chains when a ribosome has stalled, initiating the ribosome quality control (RQC) pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, PubMed:28132843, PubMed:28685749, PubMed:32011234, PubMed:36302773). Deubiquitinated by OTUD3 and USP21, antagonizing ZNF598 activity (PubMed:32011234). {ECO:0000269|PubMed:28065601, ECO:0000269|PubMed:28132843, ECO:0000269|PubMed:28685749, ECO:0000269|PubMed:32011234, ECO:0000269|PubMed:36302773}.; PTM: Ufmylated by UFL1. {ECO:0000250|UniProtKB:P60867}.
uniprot
proteins
protein_family
Universal ribosomal protein uS10 family
uniprot
proteins
pubmed
11875025
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23636399
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24524803
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28065601
uniprot
proteins
pubmed
28132843
uniprot
proteins
pubmed
28685749
uniprot
proteins
pubmed
32011234
uniprot
proteins
pubmed
36302773
uniprot
proteins
pubmed
8479924
uniprot
proteins
pubmed
8706699
uniprot
proteins
pubmed
9582194
uniprot
proteins
sequence_length
119
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23636399}.
uniprot
proteins