Mapk8ip2
entrez
60597
canonical
uniprot
Q9ERE9
canonical
ensembl
ENSMUSG00000022619
resolver
ensp
ENSMUSP00000023291
resolver
enst
ENSMUST00000023291
resolver
genesymbol
Mapk8ip2
resolver
genesymbol_syn
Ib2
resolver
genesymbol_syn
Jip2
resolver
uniprot
Q548W8
resolver
uniprot
Q6PIT2
resolver
uniprot
Q9CXI4
resolver
uniprot_entry
JIP2_MOUSE
resolver
uniprot_entry
Q548W8_MOUSE
resolver
uniprot_entry
Q6PIT2_MOUSE
resolver
uniprot_sec
Q9CXI4
resolver
amino_acid_sequence
MADRAEMFSLSTFHSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEEEEEEEEEEEDGDRQGKAGGGPGSQALAGDSLIPSPSLEESHKLRPTTLHLTTLGAQDSLNNNNGGFTSAPPSSWQETVLRSPAQEPLKELPAPLLPAEEERHEVQSLARPGCDCEGNQPPEPPASSGGASPSSDPGIEADLRSHSSGGHEGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSGRSSHLTNSIEEASSPASEPEPEPEPLHEPPRRPAFLPVGQDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRLPEEAASQANSVPQDCQDPEAGPHVELVDMDTLCGPPPPAPAAPRLGPAQPGPCLFLSNPTRDTITPLWATPGRTARPGRSCSAACSEEEEEDEEEDEEDEEDAEDSVVPPGSRTTGSTAPLDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGNDSEEDSSCEASEEEAGATLLGSDQVPEDASPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCVVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSPCWVDRFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVARSVGRAFLEYYQEHLAFACPTEDIYLE
uniprot
proteins
function
FUNCTION: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
89900
uniprot
proteins
protein_family
JIP scaffold family
uniprot
proteins
pubmed
10827199
uniprot
proteins
pubmed
11378392
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16628014
uniprot
proteins
pubmed
19893486
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
830
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q13387}. Note=Accumulates in cell surface projections. {ECO:0000250|UniProtKB:Q13387}.
uniprot
proteins