HS3ST3B1
entrez
9953
canonical
uniprot
Q9Y662
canonical
ensembl
ENSG00000125430
resolver
ensp
ENSP00000354213
resolver
ensp
ENSP00000436078
resolver
enst
ENST00000360954
resolver
enst
ENST00000466596
resolver
genesymbol
HS3ST3B1
resolver
genesymbol_syn
3OST3B1
resolver
genesymbol_syn
HS3ST3B
resolver
hgnc
HGNC:5198
resolver
uniprot
B3KN58
resolver
uniprot
D3DTS6
resolver
uniprot_entry
HS3SB_HUMAN
resolver
uniprot_sec
B3KN58
resolver
uniprot_sec
D3DTS6
resolver
amino_acid_sequence
MGQRLSGGRSCLDVPGRLLPQPPPPPPPVRRKLALLFAMLCVWLYMFLYSCAGSCAAAPGLLLLGSGSRAAHDPPALATAPDGTPPRLPFRAPPATPLASGKEMAEGAASPEEQSPEVPDSPSPISSFFSGSGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWD
uniprot
proteins
ec_number
2.8.2.30
uniprot
proteins
function
FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate (PubMed:10520990, PubMed:9988768). Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2 (PubMed:10520990, PubMed:9988768). The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry (PubMed:10520990). Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate (PubMed:9988768). {ECO:0000269|PubMed:10520990, ECO:0000269|PubMed:9988768}.
uniprot
proteins
mass_dalton
43324
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
10520990
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9988767
uniprot
proteins
pubmed
9988768
uniprot
proteins
sequence_length
390
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 33..53; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins