Atp9a
entrez
11981
canonical
uniprot
O70228
canonical
ensembl
ENSMUSG00000027546
resolver
ensp
ENSMUSP00000029060
resolver
ensp
ENSMUSP00000104804
resolver
ensp
ENSMUSP00000104806
resolver
ensp
ENSMUSP00000136793
resolver
enst
ENSMUST00000029060
resolver
enst
ENSMUST00000109175
resolver
enst
ENSMUST00000109177
resolver
enst
ENSMUST00000178504
resolver
genesymbol
Atp9a
resolver
uniprot
F7BMJ1
resolver
uniprot
F7BML0
resolver
uniprot
Q505G9
resolver
uniprot
Q8C288
resolver
uniprot
Q8C4G3
resolver
uniprot
Q8VDI5
resolver
uniprot
Q922L9
resolver
uniprot_entry
ATP9A_MOUSE
resolver
uniprot_entry
F7BMJ1_MOUSE
resolver
uniprot_entry
F7BML0_MOUSE
resolver
uniprot_entry
Q505G9_MOUSE
resolver
uniprot_entry
Q8C288_MOUSE
resolver
uniprot_entry
Q8C4G3_MOUSE
resolver
uniprot_sec
Q8VDI5
resolver
uniprot_sec
Q922L9
resolver
amino_acid_sequence
MTDSIPLQPVRHKKRVDSRPRAGCCEWLRCCGGGEPRPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFSQFRYFFNFYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTIIREAVEEIRCYVRDKEMNSQVYSRLTSRGTVKVKSSNIQVGDLILVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFLGTFTREDSDPPISESLSIENTLWAGTVIASGTVVGVVLYTGRELRSVMNTSDPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMVFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTVTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQFEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQVLNLTILQVFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLTEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFIDVYFIATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPSYSKLTS
uniprot
proteins
ec_number
7.6.2.1
uniprot
proteins
function
FUNCTION: Plays a role in regulating membrane trafficking of cargo proteins, namely endosome to plasma membrane recycling, probably acting through RAB5 and RAB11 activation (PubMed:36604604). Also involved in endosome to trans-Golgi network retrograde transport (By similarity). In complex with MON2 and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS, a transporter of Wnt morphogens in developing tissues. Participates in the formation of endosomal carriers that direct WLS trafficking back to Golgi, away from lysosomal degradation. Appears to be implicated in intercellular communication by negatively regulating the release of exosomes. The flippase activity towards membrane lipids and its role in membrane asymmetry remains to be proved. Required for the maintenance of neurite morphology and synaptic transmission (PubMed:36604604). {ECO:0000250|UniProtKB:O75110, ECO:0000269|PubMed:36604604}.
uniprot
proteins
mass_dalton
118609
uniprot
proteins
protein_family
Cation transport ATPase (P-type) (TC 3.A.3) family
uniprot
proteins
protein_family
Type IV subfamily
uniprot
proteins
pubmed
11015572
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
36604604
uniprot
proteins
pubmed
9548971
uniprot
proteins
sequence_length
1047
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Early endosome membrane {ECO:0000269|PubMed:36604604}; Multi-pass membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000269|PubMed:36604604}; Multi-pass membrane protein {ECO:0000255}. Late endosome membrane {ECO:0000269|PubMed:36604604}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:O75110}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O75110}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O75110}. Note=Efficient exit from the endoplasmic reticulum does not require CDC50A, nor CDC50B. Transiently expressed in the cell membrane. {ECO:0000250|UniProtKB:O75110}.
uniprot
proteins
transmembrane_region
TRANSMEM 70..91; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 97..119; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 304..325; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 333..354; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 842..862; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 875..893; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 924..942; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 950..972; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 979..999; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 1007..1030; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins