Nupr2
entrez
69034
canonical
uniprot
Q497P3
canonical
ensembl
ENSMUSG00000095789
resolver
ensp
ENSMUSP00000137364
resolver
ensp
ENSMUSP00000141660
resolver
ensp
ENSMUSP00000142125
resolver
enst
ENSMUST00000178355
resolver
enst
ENSMUST00000194521
resolver
enst
ENSMUST00000195766
resolver
genesymbol
Nupr2
resolver
genesymbol_syn
Nupr1l
resolver
uniprot
Q3UXQ0
resolver
uniprot
Q9D923
resolver
uniprot_entry
NUPR2_MOUSE
resolver
uniprot_sec
Q3UXQ0
resolver
uniprot_sec
Q9D923
resolver
amino_acid_sequence
MDPPTRPSVSGPRTRARPPPPEALPTVGFEEEVYDCLDYYYLRDFPASGAGRSKGRTRREQQLRTNYPVPGGHERKVAQILLNGQRKRRQRQLQPRPRTRLA
uniprot
proteins
function
FUNCTION: Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells. Involved in the G1 cell cycle arrest, and in a decrease in cell viability and cell proliferation of pancreatic cancer cells. Plays a role as a negative regulator of the protumoral factor NUPR1. {ECO:0000250|UniProtKB:A6NF83}.
uniprot
proteins
mass_dalton
11767
uniprot
proteins
protein_family
NUPR family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
102
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:A6NF83}.
uniprot
proteins