Apoa1
entrez
11806
canonical
uniprot
Q00623
canonical
ensembl
ENSMUSG00000032083
resolver
ensp
ENSMUSP00000034588
resolver
enst
ENSMUST00000034588
resolver
genesymbol
Apoa1
resolver
uniprot
O08855
resolver
uniprot
O09042
resolver
uniprot
Q8BPD5
resolver
uniprot_entry
APOA1_MOUSE
resolver
uniprot_sec
O08855
resolver
uniprot_sec
O09042
resolver
uniprot_sec
Q8BPD5
resolver
amino_acid_sequence
MKAVVLAVALVFLTGSQAWHVWQQDEPQSQWDKVKDFANVYVDAVKDSGRDYVSQFESSSLGQQLNLNLLENWDTLGSTVSQLQERLGPLTRDFWDNLEKETDWVRQEMNKDLEEVKQKVQPYLDEFQKKWKEDVELYRQKVAPLGAELQESARQKLQELQGRLSPVAEEFRDRMRTHVDSLRTQLAPHSEQMRESLAQRLAELKSNPTLNEYHTRAKTHLKTLGEKARPALEDLRHSLMPMLETLKTQVQSVIDKASETLTAQ
uniprot
proteins
function
FUNCTION: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
uniprot
proteins
mass_dalton
30616
uniprot
proteins
post_translational_modification
PTM: Glycosylated. {ECO:0000250}.; PTM: Palmitoylated. {ECO:0000250}.; PTM: May be acylated.; PTM: Phosphorylation sites are present in the extracellular medium. {ECO:0000250}.; PTM: Some tyrosine residues are chlorinated and nitrated: chlorination and nitration takes place when the lipid-free form of APOA1 is exposed to hypochlorous acid and peroxynitrite oxidants, respectively, which are generated by myeloperoxidase (MPO). {ECO:0000250|UniProtKB:P02647}.
uniprot
proteins
protein_family
Apolipoprotein A1/A4/E family
uniprot
proteins
pubmed
1478650
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1596360
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16876491
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
264
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins