Mdp1
entrez
67881
canonical
uniprot
Q9D967
canonical
ensembl
ENSMUSG00000002329
resolver
ensp
ENSMUSP00000002400
resolver
enst
ENSMUST00000002400
resolver
genesymbol
Mdp1
resolver
uniprot_entry
MGDP1_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by vanadate and zinc, and slightly by calcium. {ECO:0000269|PubMed:10889041}.
uniprot
proteins
amino_acid_sequence
MTRLPKLAVFDLDYTLWPFWVDTHVDPPFHKSSDGTVRDRRGQNIQLYPEVPEVLGRLQSLGVPVAAASRTSEIQGANQLLELFDLGKYFIQREIYPGSKVTHFERLHHKTGVPFSQMVFFDDENRNIIDVGRLGVTCIHIRDGMSLQTLTQGLETFAKAQAGL
uniprot
proteins
ec_number
3.1.3.-
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Magnesium-dependent phosphatase which may act as a tyrosine phosphatase. {ECO:0000269|PubMed:10889041, ECO:0000269|PubMed:11601995, ECO:0000269|PubMed:15461449}.
uniprot
proteins
mass_dalton
18582
uniprot
proteins
mutagenesis
MUTAGEN 11; /note="D->N,E: Abolishes enzymatic activity."; /evidence="ECO:0000269|PubMed:11601995"; MUTAGEN 13; /note="D->N: 92% loss of enzymatic activity."; /evidence="ECO:0000269|PubMed:11601995"; MUTAGEN 69; /note="S->A: Abolishes enzymatic activity."; /evidence="ECO:0000269|PubMed:11601995"; MUTAGEN 100; /note="K->R: Abolishes enzymatic activity."; /evidence="ECO:0000269|PubMed:11601995"; MUTAGEN 103; /note="H->K,A: 50% decrease in enzymatic activity."; /evidence="ECO:0000269|PubMed:10889041"; MUTAGEN 122; /note="D->N: Abolishes enzymatic activity."; MUTAGEN 123; /note="D->N: Abolishes enzymatic activity."; MUTAGEN 127; /note="N->D: 50% decrease in enzymatic activity."; MUTAGEN 138; /note="C->S,A,G: No effect on enzymatic activity."; /evidence="ECO:0000269|PubMed:10889041
uniprot
proteins
protein_family
HAD-like hydrolase superfamily
uniprot
proteins
pubmed
10889041
uniprot
proteins
pubmed
11601995
uniprot
proteins
pubmed
15461449
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
164
uniprot
proteins