SPATA16
entrez
83893
canonical
uniprot
Q9BXB7
canonical
ensembl
ENSG00000144962
resolver
ensp
ENSP00000341765
resolver
enst
ENST00000351008
resolver
genesymbol
SPATA16
resolver
hgnc
HGNC:29935
resolver
uniprot
A0A140VJV8
resolver
uniprot
Q0R0N4
resolver
uniprot
Q0R0S0
resolver
uniprot
Q0R0W2
resolver
uniprot
Q0R129
resolver
uniprot
Q0R131
resolver
uniprot
Q0R140
resolver
uniprot
Q0R1B8
resolver
uniprot
Q0R1G5
resolver
uniprot
Q0R1I2
resolver
uniprot
Q0R1J6
resolver
uniprot
Q0R1S4
resolver
uniprot
Q0R202
resolver
uniprot
Q0R280
resolver
uniprot
Q0R2F8
resolver
uniprot
Q0R2N6
resolver
uniprot
Q0R2N7
resolver
uniprot
Q0R2R0
resolver
uniprot
Q0R2R1
resolver
uniprot
Q0R2S3
resolver
uniprot
Q0R2S4
resolver
uniprot
Q0R2S5
resolver
uniprot
Q0R2T4
resolver
uniprot
Q0R2T7
resolver
uniprot
Q0R2U2
resolver
uniprot
Q0R2U8
resolver
uniprot
Q0R2U9
resolver
uniprot
Q0R2V5
resolver
uniprot
Q0R2V7
resolver
uniprot
Q8NE67
resolver
uniprot_entry
A0A140VJV8_HUMAN
resolver
uniprot_entry
SPT16_HUMAN
resolver
uniprot_sec
Q0R0N4
resolver
uniprot_sec
Q0R0S0
resolver
uniprot_sec
Q0R0W2
resolver
uniprot_sec
Q0R129
resolver
uniprot_sec
Q0R131
resolver
uniprot_sec
Q0R140
resolver
uniprot_sec
Q0R1B8
resolver
uniprot_sec
Q0R1G5
resolver
uniprot_sec
Q0R1I2
resolver
uniprot_sec
Q0R1J6
resolver
uniprot_sec
Q0R1S4
resolver
uniprot_sec
Q0R202
resolver
uniprot_sec
Q0R280
resolver
uniprot_sec
Q0R2F8
resolver
uniprot_sec
Q0R2N6
resolver
uniprot_sec
Q0R2N7
resolver
uniprot_sec
Q0R2R0
resolver
uniprot_sec
Q0R2R1
resolver
uniprot_sec
Q0R2S3
resolver
uniprot_sec
Q0R2S4
resolver
uniprot_sec
Q0R2S5
resolver
uniprot_sec
Q0R2T4
resolver
uniprot_sec
Q0R2T7
resolver
uniprot_sec
Q0R2U2
resolver
uniprot_sec
Q0R2U8
resolver
uniprot_sec
Q0R2U9
resolver
uniprot_sec
Q0R2V5
resolver
uniprot_sec
Q0R2V7
resolver
uniprot_sec
Q8NE67
resolver
amino_acid_sequence
MDAGSSRSLENAVNRIYHDQLVPKINTSKKMSTLAHPPNILEMSQEIKKNCGGKQVEITLERTKMTKGIKEKQSNDLEKAAFKRKAEGEEKPTRKKQAKITELDNQLITMPLPHIPLKNIMDVEMKLVYIDEMGVRYEFVESFMSTGSQPTCQAAEIVDPLSVHNFSFLPQIDKWLQVALKDASSCYRQKKYALAAGQFRTALELCSKGAVLGEPFDAPAEDIASVASFIETKLVTCYLRMRKPDLALNHAHRSIVLNPAYFRNHLRQATVFRCLERYSEAARSAMIADYMFWLGGGREESISKLIKLYWQAMIEEAITRAESFSVMYTPFATKIRADKIEKVKDAFTKTHPAYAEYMYTDLQALHMLPQTVDWSSFPPQQYLLTLGFKNKDDGKFLEKISSRKLPIFTEHKTPFGLTREDTVRQMETMGKRILPILDFIRSTQLNGSFPASSGVMEKLQYASLLSQLQRVKEQSQVINQAMAELATIPYLQDISQQEAELLQSLMADAMDTLEGRRNNNERVWNMIQKVGQIEDFLYQLEDSFLKTKKLRTARRQKTKMKRLQTVQQR
uniprot
proteins
disease_involvement
DISEASE: Spermatogenic failure 6 (SPGF6) [MIM:102530]: An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome, which can be totally absent in most severe cases. Additional features are an abnormal nuclear shape and abnormal arrangement of the mitochondria of the spermatozoon. {ECO:0000269|PubMed:17847006}. Note=The disease is caused by variants affecting the gene represented in this entry. An autosomal recessive variation of SPATA16 has been shown to be responsible for the disease in a consanguineous family with members homozygous for the variation.
uniprot
proteins
function
FUNCTION: Essential for spermiogenesis and male fertility (By similarity). Involved in the formation of sperm acrosome during spermatogenesis. {ECO:0000250|UniProtKB:Q8C636, ECO:0000269|PubMed:12529416}.
uniprot
proteins
mass_dalton
65263
uniprot
proteins
protein_family
SPATA16 family
uniprot
proteins
pubmed
12529416
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
17665087
uniprot
proteins
pubmed
17847006
uniprot
proteins
sequence_length
569
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:12529416}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q8C636}. Note=Shift from Golgi to sperm acrosome. {ECO:0000250|UniProtKB:Q8C636}.
uniprot
proteins