AP1G2
entrez
8906
canonical
uniprot
O75843
canonical
ensembl
ENSG00000213983
resolver
ensp
ENSP00000312442
resolver
ensp
ENSP00000380309
resolver
ensp
ENSP00000558365
resolver
ensp
ENSP00000558370
resolver
ensp
ENSP00000558377
resolver
ensp
ENSP00000558378
resolver
ensp
ENSP00000648257
resolver
ensp
ENSP00000755201
resolver
enst
ENST00000308724
resolver
enst
ENST00000397120
resolver
enst
ENST00000888306
resolver
enst
ENST00000888318
resolver
enst
ENST00000888319
resolver
genesymbol
AP1G2
resolver
hgnc
HGNC:556
resolver
uniprot
D3DS51
resolver
uniprot
O75504
resolver
uniprot
Q86U03
resolver
uniprot
Q86V28
resolver
uniprot_entry
AP1G2_HUMAN
resolver
uniprot_entry
Q86U03_HUMAN
resolver
uniprot_entry
Q86V28_HUMAN
resolver
uniprot_sec
D3DS51
resolver
uniprot_sec
O75504
resolver
amino_acid_sequence
MVVPSLKLQDLIEEIRGAKTQAQEREVIQKECAHIRASFRDGDPVHRHRQLAKLLYVHMLGYPAHFGQMECLKLIASSRFTDKRVGYLGAMLLLDERHDAHLLITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKVPELSSVFLPPCAQLLHERHHGILLGTITLITELCERSPAALRHFRKVVPQLVHILRTLVTMGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQSDHSAVQRHRPTVVECLRETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPTKRWHIDTILHVLTTAGTHVRDDAVANLTQLIGGAQELHAYSVRRLYNALAEDISQQPLVQVAAWCIGEYGDLLLAGNCEEIEPLQVDEEEVLALLEKVLQSHMSLPATRGYALTALMKLSTRLCGDNNRIRQVVSIYGSCLDVELQQRAVEYDTLFRKYDHMRAAILEKMPLVERDGPQADEEAKESKEAAQLSEAAPVPTEPQASQLLDLLDLLDGASGDVQHPPHLDPSPGGALVHLLDLPCVPPPPAPIPDLKVFEREGVQLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGGLPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESWQ
uniprot
proteins
function
FUNCTION: May function in protein sorting in late endosomes or multivesucular bodies (MVBs). {ECO:0000269|PubMed:9733768}.; FUNCTION: (Microbial infection) Involved in MVB-assisted maturation of hepatitis B virus (HBV). {ECO:0000269|PubMed:16867982, ECO:0000269|PubMed:17553870}.
uniprot
proteins
mass_dalton
87117
uniprot
proteins
mutagenesis
MUTAGEN 369; /note="L->G: Greatly diminishes interaction with ubiquitin; when associated with G-372."; /evidence="ECO:0000269|PubMed:16867982"; MUTAGEN 372; /note="A->G: Greatly diminishes interaction with ubiquitin; when associated with G-369."; /evidence="ECO:0000269|PubMed:16867982"; MUTAGEN 372; /note="A->G: Greatly diminishes interaction with ubiquitin; when associated with G-376."; /evidence="ECO:0000269|PubMed:16867982"; MUTAGEN 376; /note="S->G: Greatly diminishes interaction with ubiquitin; when associated with G-372."; /evidence="ECO:0000269|PubMed:16867982
uniprot
proteins
protein_family
Adaptor complexes large subunit family
uniprot
proteins
pubmed
11333915
uniprot
proteins
pubmed
14665628
uniprot
proteins
pubmed
16867982
uniprot
proteins
pubmed
17553870
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
9733768
uniprot
proteins
pubmed
9762922
uniprot
proteins
sequence_length
785
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:11333915, ECO:0000269|PubMed:9762922}; Peripheral membrane protein; Cytoplasmic side {ECO:0000269|PubMed:11333915}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:9733768}; Peripheral membrane protein. Endosome membrane {ECO:0000269|PubMed:16867982}; Peripheral membrane protein. Note=Mainly localized to perinuclear vesicular structures (PubMed:9733768). Colocalizes with HBV major surface antigen L and HBV core protein C in CD63-containing compartments (PubMed:16867982). Colocalizes with HBV major surface antigen L to cis-Golgi-like structures (PubMed:11333915).
uniprot
proteins