Abhd17b
entrez
309399
canonical
uniprot
Q6AY17
canonical
ensembl
ENSRNOG00000012514
resolver
ensembl
ENSRNOG00055030503
resolver
ensembl
ENSRNOG00060024979
resolver
ensembl
ENSRNOG00065024476
resolver
ensp
ENSRNOP00000047508
resolver
ensp
ENSRNOP00055043755
resolver
ensp
ENSRNOP00060035789
resolver
ensp
ENSRNOP00065034335
resolver
enst
ENSRNOT00000044486
resolver
enst
ENSRNOT00055052948
resolver
enst
ENSRNOT00060043233
resolver
enst
ENSRNOT00065042000
resolver
genesymbol
Abhd17b
resolver
uniprot_entry
AB17B_RAT
resolver
amino_acid_sequence
MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVSQELVNL
uniprot
proteins
ec_number
3.1.2.22
uniprot
proteins
function
FUNCTION: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Has depalmitoylating activity towards GAP43. Has depalmitoylating activity towards MAP6. Has depalmitoylating activity towards NRAS. {ECO:0000250|UniProtKB:Q5VST6, ECO:0000250|UniProtKB:Q7M759}.
uniprot
proteins
mass_dalton
32201
uniprot
proteins
post_translational_modification
PTM: Palmitoylated on cysteine residues located in a cysteine cluster at the N-terminus which promotes membrane localization. Palmitoylation is required for post-synaptic localization and for depalmitoylating activity towards DLG4/PSD95. {ECO:0000250|UniProtKB:Q7M759}.
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
ABHD17 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
27307232
uniprot
proteins
sequence_length
288
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:27307232}; Lipid-anchor {ECO:0000269|PubMed:27307232}; Cytoplasmic side {ECO:0000269|PubMed:27307232}. Recycling endosome membrane {ECO:0000269|PubMed:27307232}; Lipid-anchor {ECO:0000269|PubMed:27307232}; Cytoplasmic side {ECO:0000269|PubMed:27307232}. Cell projection, dendritic spine {ECO:0000269|PubMed:27307232}. Postsynaptic density membrane {ECO:0000269|PubMed:27307232}.
uniprot
proteins