Nol12
entrez
97961
canonical
uniprot
Q8BG17
canonical
ensembl
ENSMUSG00000033099
resolver
ensp
ENSMUSP00000042908
resolver
ensp
ENSMUSP00000116103
resolver
ensp
ENSMUSP00000261967
resolver
enst
ENSMUST00000138880
resolver
genesymbol
Nol12
resolver
genesymbol_syn
Nop25
resolver
uniprot
Q91VI1
resolver
uniprot_entry
NOL12_MOUSE
resolver
uniprot_sec
Q91VI1
resolver
amino_acid_sequence
MGRNKKKKKRDGDDRRPRLVLNFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPLPEQGDQDGSQEEEMSSLEKPTKALPRKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHNGE
uniprot
proteins
function
FUNCTION: Multifunctional RNA binding protein that plays a role in RNA metabolism and DNA maintenance. Participates in the resolution of DNA stress and the maintenance of genome integrity by localizing to sites of DNA insults. Also plays a role in proper nucleolar organization by limiting nucleolar size and regulating nucleolar number. Mechanistically, regulates the nucleolar levels of fibrillarin and nucleolin, two key players in pre-rRNA processing and ribosome assembly. {ECO:0000250|UniProtKB:Q9UGY1, ECO:0000269|PubMed:16430885}.
uniprot
proteins
mass_dalton
25356
uniprot
proteins
protein_family
RRP17 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16430885
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
217
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16430885}. Nucleus {ECO:0000250|UniProtKB:Q9UGY1}. Cytoplasm {ECO:0000250|UniProtKB:Q9UGY1}.
uniprot
proteins