Ift74
entrez
67694
canonical
uniprot
Q8BKE9
canonical
ensembl
ENSMUSG00000028576
resolver
ensp
ENSMUSP00000030311
resolver
ensp
ENSMUSP00000102721
resolver
ensp
ENSMUSP00000190695
resolver
enst
ENSMUST00000030311
resolver
enst
ENSMUST00000107104
resolver
genesymbol
Ift74
resolver
genesymbol_syn
Ccdc2
resolver
genesymbol_syn
Cmg1
resolver
uniprot
B1AWG1
resolver
uniprot
B1AWG2
resolver
uniprot
Q80ZI3
resolver
uniprot
Q9CSY1
resolver
uniprot
Q9CUS0
resolver
uniprot
Q9D9T5
resolver
uniprot_entry
B1AWG1_MOUSE
resolver
uniprot_entry
IFT74_MOUSE
resolver
uniprot_sec
B1AWG2
resolver
uniprot_sec
Q80ZI3
resolver
uniprot_sec
Q9CSY1
resolver
uniprot_sec
Q9CUS0
resolver
uniprot_sec
Q9D9T5
resolver
amino_acid_sequence
MASNHKSSAPRPISRGGIGLTGRPPSGIRPPSGNVRVATAMPPTTARPGSRGGPLGTGGVLSSQIKVADRPVTQQGLSGMKTGMKGPQRQILDKSYYLGLLRSKISELTTEINKLQKEIEMYNQENSVYLSYEKRAETLAVEIKDFQGQLADYNMLVDKLNTNTEMEEVMSDYNMLKAQNDRETQSMDVIFTERQAKEKQIRSVEEEVEQEKQAADGIIKNMSPEKQVKYIEMKTTNEKLLQELDTLQQQLDSLNMKKESLETEIAHSQVKQEAVLLYEKLYELESHRDQMIAEDKSMGSPMEERERLLKQVKEDNQEIASMERQLTDIKEKINQFSEEIRQLDMDLEEHQGEMNQKYKELKKREENMDAFIETFEETKNQELERKAQIEASIITLLEHCSRNINRMKQISSITNQELKMMQDDLSFKSTEMQKSQTTARNLTSDSQRLQLDLQKMELLESKMTEEQQSLKNKIKQMTADLETYSDLAALKSSAEEKKKKLHQERTVLSTHRNAFKKIMEKLTSDYDTLKRQLQDNETHAQLTNLERKWQHLEQNNFVMKEFIATKSQESDYQPVIKNVMKQIAEYNKTIMDALHNASRS
uniprot
proteins
function
FUNCTION: Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis (By similarity). Essential for flagellogenesis during spermatogenesis (PubMed:31004481). {ECO:0000250|UniProtKB:Q96LB3, ECO:0000269|PubMed:31004481}.
uniprot
proteins
mass_dalton
69301
uniprot
proteins
protein_family
IFT74 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16775004
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23810713
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
31004481
uniprot
proteins
sequence_length
600
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000269|PubMed:16775004}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q96LB3}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:31004481}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:31004481}. Note=In male germ cells, strongly expressed in the vesicles of spermatocytes and round spermatids and also in the acrosome and centrosome regions of elongating spermatids and in developing sperm tails. {ECO:0000269|PubMed:31004481}.
uniprot
proteins