OC90
entrez
729330
canonical
uniprot
Q02509
canonical
ensembl
ENSG00000253117
resolver
ensp
ENSP00000254627
resolver
genesymbol
OC90
resolver
genesymbol_syn
PLA2L
resolver
hgnc
HGNC:8100
resolver
uniprot
B4DNG8
resolver
uniprot_entry
OC90_HUMAN
resolver
uniprot_sec
B4DNG8
resolver
amino_acid_sequence
MIAFLLTSVLMIPHAGGHPLDTPHLPQELPPGLPNNINITFFSGMFKNVESVAEIFDCLGPHFTWLQAVFTNFPVLIQFVNGMKCVAGLCPRDFEDYGCTCRFEMEGLPVDESDSCCFQHRRCYEEAAEMDCLQDPAKLSTEVNCVSKKIICESKDNCEHLLCTCDKAAIECLARSSLNSSLNLLDTSFCLAQTPETTIKEDLTTLLPRVVPVEPTDTSLTALSGEEAGHDQEGVGAARATSPPGSAEIVATRVTAKIVTLVPAGIKSLGLAVSSVENDPEETTEKACDRFTFLHLGSGDNMQVMPQLGEMLFCLTSRCPEEFESYGCYCGQEGRGEPRDDLDRCCLSHHCCLEQVRRLGCLLERLPWSPVVCVDHTPKCGGQSLCEKLLCACDQTAAECMTSASFNQSLKSPSRLGCPGQPAACEDSLHPVPAAPTLGSSSEEDSEEDPPQEDLGRAKRFLRKSLGPLGIGPLHGR
uniprot
proteins
function
FUNCTION: Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure. Together with OTOL1, modulates calcite crystal morphology and growth kinetics. It is unlikely that this protein has phospholipase A2 activity. {ECO:0000250|UniProtKB:Q9Z0L3}.
uniprot
proteins
mass_dalton
51728
uniprot
proteins
protein_family
Phospholipase A2 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
8382789
uniprot
proteins
sequence_length
477
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P81869}.
uniprot
proteins