RGS1
entrez
5996
canonical
uniprot
Q08116
canonical
ensembl
ENSG00000090104
resolver
ensp
ENSP00000356429
resolver
genesymbol
RGS1
resolver
genesymbol_syn
1R20
resolver
genesymbol_syn
BL34
resolver
genesymbol_syn
IER1
resolver
hgnc
HGNC:9991
resolver
uniprot
B2RDM9
resolver
uniprot
B4DZY0
resolver
uniprot
Q07918
resolver
uniprot
Q9H1W2
resolver
uniprot_entry
RGS1_HUMAN
resolver
uniprot_sec
B2RDM9
resolver
uniprot_sec
B4DZY0
resolver
uniprot_sec
Q07918
resolver
uniprot_sec
Q9H1W2
resolver
amino_acid_sequence
MRAAAISTPKLDKMPGMFFSANPKELKGTTHSLLDDKMQKRRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK
uniprot
proteins
function
FUNCTION: Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541). {ECO:0000250|UniProtKB:Q9JL25, ECO:0000269|PubMed:10480894, ECO:0000269|PubMed:18434541}.
uniprot
proteins
mass_dalton
23858
uniprot
proteins
pubmed
10480894
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
18434541
uniprot
proteins
pubmed
8241276
uniprot
proteins
pubmed
8473738
uniprot
proteins
sequence_length
209
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10480894}; Peripheral membrane protein {ECO:0000269|PubMed:10480894}; Cytoplasmic side {ECO:0000269|PubMed:10480894}. Cytoplasm, cytosol {ECO:0000269|PubMed:10480894}.
uniprot
proteins