CLIP3
entrez
25999
canonical
uniprot
Q96DZ5
canonical
ensembl
ENSG00000105270
resolver
ensp
ENSP00000353732
resolver
ensp
ENSP00000466832
resolver
ensp
ENSP00000574738
resolver
ensp
ENSP00000574739
resolver
enst
ENST00000360535
resolver
enst
ENST00000593074
resolver
enst
ENST00000904679
resolver
enst
ENST00000904680
resolver
genesymbol
CLIP3
resolver
genesymbol_syn
CLIPR59
resolver
hgnc
HGNC:24314
resolver
uniprot
A8K0E4
resolver
uniprot
Q8WWL1
resolver
uniprot
Q96C99
resolver
uniprot
Q9UFT7
resolver
uniprot_entry
CLIP3_HUMAN
resolver
uniprot_sec
A8K0E4
resolver
uniprot_sec
Q8WWL1
resolver
uniprot_sec
Q96C99
resolver
uniprot_sec
Q9UFT7
resolver
amino_acid_sequence
MTKTDPAPMAPPPRGEEEEEEEEDEPVPEAPSPTQERRQKPVVHPSAPAPLPKDYAFTFFDPNDPACQEILFDPQTTIPELFAIVRQWVPQVQHKIDVIGNEILRRGCHVNDRDGLTDMTLLHYACKAGAHGVGDPAAAVRLSQQLLALGADVTLRSRWTNMNALHYAAYFDVPDLVRVLLKGARPRVVNSTCSDFNHGSALHIAASSLCLGAAKCLLEHGANPALRNRKGQVPAEVVPDPMDMSLDKAEAALVAKELRTLLEEAVPLSCALPKVTLPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGVRYFICPPKQGLFASVSKISKAVDAPPSSVTSTPRTPRMDFSRVTGKGRREHKGKKKTPSSPSLGSLQQRDGAKAEVGDQVLVAGQKQGIVRFYGKTDFAPGYWYGIELDQPTGKHDGSVFGVRYFTCPPRHGVFAPASRIQRIGGSTDSPGDSVGAKKVHQVTMTQPKRTFTTVRTPKDIASENSISRLLFCCWFPWMLRAEMQS
uniprot
proteins
function
FUNCTION: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes. {ECO:0000269|PubMed:19139280}.
uniprot
proteins
mass_dalton
59560
uniprot
proteins
mutagenesis
MUTAGEN 509; /note="P->A: Inhibits interaction with ZDHHC13 and ZDHHC17."; /evidence="ECO:0000269|PubMed:26198635"; MUTAGEN 534..535; /note="CC->AA: Strongly reduced plasma membrane association and decrease in the levels of Akt at the plasma membrane."; /evidence="ECO:0000269|PubMed:24001771
uniprot
proteins
post_translational_modification
PTM: Palmitoylation by ZDHHC17 regulates association with the plasma membrane. {ECO:0000269|PubMed:24001771}.
uniprot
proteins
pubmed
11854307
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19139280
uniprot
proteins
pubmed
24001771
uniprot
proteins
pubmed
26198635
uniprot
proteins
pubmed
28882895
uniprot
proteins
sequence_length
547
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24001771}; Lipid-anchor {ECO:0000269|PubMed:24001771}. Cytoplasm {ECO:0000269|PubMed:24001771}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:24001771}. Note=Localized to Golgi stacks as well as on tubulovesicular elements juxtaposed to Golgi cisternae.
uniprot
proteins