Tmem25
entrez
71687
canonical
uniprot
Q9DCF1
canonical
ensembl
ENSMUSG00000002032
resolver
ensp
ENSMUSP00000002100
resolver
ensp
ENSMUSP00000110353
resolver
ensp
ENSMUSP00000244923
resolver
ensp
ENSMUSP00000244949
resolver
ensp
ENSMUSP00000244956
resolver
ensp
ENSMUSP00000347123
resolver
enst
ENSMUST00000114705
resolver
genesymbol
Tmem25
resolver
uniprot
A0A1N9MYB8
resolver
uniprot
Q3TMP3
resolver
uniprot
Q6PAK7
resolver
uniprot_entry
A0A1N9MYB8_MOUSE
resolver
uniprot_entry
TMM25_MOUSE
resolver
uniprot_sec
Q3TMP3
resolver
uniprot_sec
Q6PAK7
resolver
amino_acid_sequence
MELPLSQATLRHTLLLLPALLSSGQGELAPQIDGQTWAERALRENEHHAFTCRVAGGSATPRLAWYLDGQLQEATTSRLLSVGGDAFSGGTSTFTVTAQRSQHELNCSLQDPGSGRPANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPPANVTWIDQDGPVTVNASDFLVLDAQNYPWLTNHTVQLQLRSLAHNLSVVATNDVGVTSASLPAPGLLATRIEVPLLGIVVAGGLALGTLVGFSTLVACLVCRKEKKTKGPSRRPSLISSDSNNLKLNNVRLPRENMSLPSNLQLNDLTPDLRGKATERPMAQHSSRPELLEAEPGGLLTSRGFIRLPMLGYIYRVSSVSSDEIWL
uniprot
proteins
function
FUNCTION: In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability. {ECO:0000269|PubMed:31424425}.
uniprot
proteins
mass_dalton
39170
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
31424425
uniprot
proteins
sequence_length
365
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Late endosome {ECO:0000269|PubMed:31424425}. Lysosome {ECO:0000269|PubMed:31424425}.; SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 233..253; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins