ST3GAL3
entrez
6487
canonical
uniprot
Q11203
canonical
ensembl
ENSG00000126091
resolver
ensp
ENSP00000262915
resolver
ensp
ENSP00000316999
resolver
ensp
ENSP00000317192
resolver
ensp
ENSP00000330463
resolver
ensp
ENSP00000333494
resolver
ensp
ENSP00000335633
resolver
ensp
ENSP00000354748
resolver
ensp
ENSP00000355341
resolver
ensp
ENSP00000361437
resolver
ensp
ENSP00000361442
resolver
ensp
ENSP00000361444
resolver
ensp
ENSP00000361447
resolver
ensp
ENSP00000361449
resolver
ensp
ENSP00000432682
resolver
ensp
ENSP00000434876
resolver
ensp
ENSP00000435603
resolver
ensp
ENSP00000439634
resolver
ensp
ENSP00000493823
resolver
ensp
ENSP00000494146
resolver
ensp
ENSP00000494201
resolver
ensp
ENSP00000495333
resolver
ensp
ENSP00000495624
resolver
ensp
ENSP00000495683
resolver
ensp
ENSP00000496289
resolver
ensp
ENSP00000527247
resolver
ensp
ENSP00000631724
resolver
ensp
ENSP00000796717
resolver
enst
ENST00000642331
resolver
enst
ENST00000643252
resolver
enst
ENST00000646686
resolver
enst
ENST00000647237
resolver
genesymbol
ST3GAL3
resolver
genesymbol_syn
SIAT6
resolver
hgnc
HGNC:10866
resolver
uniprot
A0A2R8Y6H4
resolver
uniprot
A0A2R8Y6L4
resolver
uniprot
A0A2R8Y732
resolver
uniprot
A0A2R8YDJ6
resolver
uniprot
A9Z1W2
resolver
uniprot
D3DPX8
resolver
uniprot
Q5T4W9
resolver
uniprot
Q5T4X0
resolver
uniprot
Q5T4X7
resolver
uniprot
Q5T4X8
resolver
uniprot
Q5T4X9
resolver
uniprot
Q5T4Y0
resolver
uniprot
Q5T4Y2
resolver
uniprot
Q5T4Y3
resolver
uniprot
Q5T4Y4
resolver
uniprot
Q86UR6
resolver
uniprot
Q86UR7
resolver
uniprot
Q86UR8
resolver
uniprot
Q86UR9
resolver
uniprot
Q86US0
resolver
uniprot
Q86US1
resolver
uniprot
Q86US2
resolver
uniprot
Q8IX41
resolver
uniprot
Q8IX42
resolver
uniprot
Q8IX43
resolver
uniprot
Q8IX44
resolver
uniprot
Q8IX45
resolver
uniprot
Q8IX46
resolver
uniprot
Q8IX47
resolver
uniprot
Q8IX48
resolver
uniprot
Q8IX49
resolver
uniprot
Q8IX50
resolver
uniprot
Q8IX51
resolver
uniprot
Q8IX52
resolver
uniprot
Q8IX53
resolver
uniprot
Q8IX54
resolver
uniprot
Q8IX55
resolver
uniprot
Q8IX56
resolver
uniprot
Q8IX57
resolver
uniprot
Q8IX58
resolver
uniprot_entry
A0A2R8Y6H4_HUMAN
resolver
uniprot_entry
A0A2R8Y6L4_HUMAN
resolver
uniprot_entry
A0A2R8Y732_HUMAN
resolver
uniprot_entry
A0A2R8YDJ6_HUMAN
resolver
uniprot_entry
SIAT6_HUMAN
resolver
uniprot_sec
A9Z1W2
resolver
uniprot_sec
D3DPX8
resolver
uniprot_sec
Q5T4W9
resolver
uniprot_sec
Q5T4X0
resolver
uniprot_sec
Q5T4X7
resolver
uniprot_sec
Q5T4X8
resolver
uniprot_sec
Q5T4X9
resolver
uniprot_sec
Q5T4Y0
resolver
uniprot_sec
Q5T4Y2
resolver
uniprot_sec
Q5T4Y3
resolver
uniprot_sec
Q5T4Y4
resolver
uniprot_sec
Q86UR6
resolver
uniprot_sec
Q86UR7
resolver
uniprot_sec
Q86UR8
resolver
uniprot_sec
Q86UR9
resolver
uniprot_sec
Q86US0
resolver
uniprot_sec
Q86US1
resolver
uniprot_sec
Q86US2
resolver
uniprot_sec
Q8IX41
resolver
uniprot_sec
Q8IX42
resolver
uniprot_sec
Q8IX43
resolver
uniprot_sec
Q8IX44
resolver
uniprot_sec
Q8IX45
resolver
uniprot_sec
Q8IX46
resolver
uniprot_sec
Q8IX47
resolver
uniprot_sec
Q8IX48
resolver
uniprot_sec
Q8IX49
resolver
uniprot_sec
Q8IX50
resolver
uniprot_sec
Q8IX51
resolver
uniprot_sec
Q8IX52
resolver
uniprot_sec
Q8IX53
resolver
uniprot_sec
Q8IX54
resolver
uniprot_sec
Q8IX55
resolver
uniprot_sec
Q8IX56
resolver
uniprot_sec
Q8IX57
resolver
uniprot_sec
Q8IX58
resolver
amino_acid_sequence
MGLLVFVRNLLLALCLFLVLGFLYYSAWKLHLLQWEEDSNSVVLSFDSAGQTLGSEYDRLGFLLNLDSKLPAELATKYANFSEGACKPGYASALMTAIFPRFSKPAPMFLDDSFRKWARIREFVPPFGIKGQDNLIKAILSVTKEYRLTPALDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGSKTTLRITYPEGAMQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGFGYDMSTPNAPLHYYETVRMAAIKESWTHNIQREKEFLRKLVKARVITDLSSGI
uniprot
proteins
disease_involvement
DISEASE: Intellectual developmental disorder, autosomal recessive 12 (MRT12) [MIM:611090]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. {ECO:0000269|PubMed:21907012}. Note=The disease is caused by variants affecting the gene represented in this entry.; DISEASE: Developmental and epileptic encephalopathy 15 (DEE15) [MIM:615006]: A form of epilepsy that manifests in the neonatal or the early infantile period as severely impaired cognitive and motor development, due to recurrent clinical seizures or prominent interictal epileptiform discharges. Patients develop infantile spasms, mainly of the flexor type, between 3 and 7 months of age, which are accompanied by hypsarrhythmia on EEG. Other features include poor eye contact, hypotonia, primitive reflexes, and irritability. Seizures evolve clinically to Lennox-Gastaut syndrome. {ECO:0000269|PubMed:23252400}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
2.4.3.6
uniprot
proteins
function
FUNCTION: Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc. {ECO:0000250|UniProtKB:P97325}.
uniprot
proteins
mass_dalton
42171
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation.
uniprot
proteins
post_translational_modification
PTM: The soluble form derives from the membrane form by proteolytic processing.
uniprot
proteins
protein_family
Glycosyltransferase 29 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21907012
uniprot
proteins
pubmed
23252400
uniprot
proteins
pubmed
8333853
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
uniprot
proteins
transmembrane_region
TRANSMEM 9..28; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins