Tac3
entrez
29191
canonical
uniprot
P08435
canonical
ensembl
ENSRNOG00000004229
resolver
ensp
ENSRNOP00000005679
resolver
enst
ENSRNOT00000005679
resolver
genesymbol
Tac3
resolver
genesymbol_syn
Nknb
resolver
genesymbol_syn
Tac2
resolver
uniprot
G3V6J3
resolver
uniprot_entry
G3V6J3_RAT
resolver
uniprot_entry
TKNK_RAT
resolver
amino_acid_sequence
MRSAMLFAAVLALSLAWTFGAACEEPQEQGGRLSKDSDLSLLPPPLLRRLYDSRSISLEGLLKVLSKASVGPKETSLPQKRDMHDFFVGLMGKRNSQPDTPADVVEENTPSFGVLK
uniprot
proteins
function
FUNCTION: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.; FUNCTION: [Neurokinin-B]: Is a ligand for TACR3, and triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C (PubMed:1370820). Binding to TACR3 also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP) (PubMed:1370820). Is a critical central regulator of gonadal function (By similarity). {ECO:0000250|UniProtKB:Q9UHF0, ECO:0000269|PubMed:1370820}.
uniprot
proteins
mass_dalton
12660
uniprot
proteins
protein_family
Tachykinin family
uniprot
proteins
pubmed
1370820
uniprot
proteins
pubmed
3479225
uniprot
proteins
sequence_length
116
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins