CDIPT
entrez
10423
canonical
uniprot
O14735
canonical
ensembl
ENSG00000103502
resolver
ensp
ENSP00000219789
resolver
ensp
ENSP00000457340
resolver
genesymbol
CDIPT
resolver
genesymbol_syn
PIS
resolver
genesymbol_syn
PIS1
resolver
hgnc
HGNC:1769
resolver
uniprot
A8K3L7
resolver
uniprot
B4DUV0
resolver
uniprot
H3BTV1
resolver
uniprot
Q6FGU1
resolver
uniprot
Q6ZN70
resolver
uniprot_entry
A8K3L7_HUMAN
resolver
uniprot_entry
CDIPT_HUMAN
resolver
uniprot_sec
B4DUV0
resolver
uniprot_sec
H3BTV1
resolver
uniprot_sec
Q6FGU1
resolver
uniprot_sec
Q6ZN70
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by PtdIns (product inhibition), phosphatidylinositol phosphate, and nucleoside di- and tri-phosphates.
uniprot
proteins
amino_acid_sequence
MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLITAARNMAALDAADRAKKK
uniprot
proteins
ec_number
2.7.8.11
uniprot
proteins
function
FUNCTION: Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. {ECO:0000269|PubMed:8110188, ECO:0000269|PubMed:9407135}.
uniprot
proteins
mass_dalton
23539
uniprot
proteins
protein_family
CDP-alcohol phosphatidyltransferase class-I family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15616553
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
8110188
uniprot
proteins
pubmed
9407135
uniprot
proteins
sequence_length
213
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305|PubMed:8110188}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000305|PubMed:8110188}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 6..26; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 28..48; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 74..94; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 96..116; /note="Helical"; /evidence="ECO:0000305"; TRANSMEM 140..160; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 175..195; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins