DENND5B
entrez
160518
canonical
uniprot
Q6ZUT9
canonical
ensembl
ENSG00000170456
resolver
ensp
ENSP00000346238
resolver
ensp
ENSP00000373734
resolver
ensp
ENSP00000442938
resolver
ensp
ENSP00000444889
resolver
ensp
ENSP00000567877
resolver
ensp
ENSP00000567878
resolver
ensp
ENSP00000567879
resolver
ensp
ENSP00000567880
resolver
ensp
ENSP00000618295
resolver
ensp
ENSP00000618296
resolver
ensp
ENSP00000618297
resolver
ensp
ENSP00000618298
resolver
ensp
ENSP00000618299
resolver
ensp
ENSP00000669801
resolver
enst
ENST00000536562
resolver
genesymbol
DENND5B
resolver
hgnc
HGNC:28338
resolver
uniprot
B5ME75
resolver
uniprot
G3V1S3
resolver
uniprot
Q59FW8
resolver
uniprot
Q68CZ7
resolver
uniprot
Q6NUJ0
resolver
uniprot
Q7Z3F9
resolver
uniprot
Q8N973
resolver
uniprot
Q8WUC8
resolver
uniprot_entry
DEN5B_HUMAN
resolver
uniprot_entry
G3V1S3_HUMAN
resolver
uniprot_sec
B5ME75
resolver
uniprot_sec
Q59FW8
resolver
uniprot_sec
Q68CZ7
resolver
uniprot_sec
Q6NUJ0
resolver
uniprot_sec
Q7Z3F9
resolver
uniprot_sec
Q8N973
resolver
uniprot_sec
Q8WUC8
resolver
amino_acid_sequence
MSGSCAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHYSSVYASSSCSMDSLASSLDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPSELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLVQFGIPPEGSLHCSESTSKLKNMVLKDLVNDKKNGNVCTNNISMYELLKGNETIARLQALAKRTGVAVEKMDLSASLGEKDKDLKLHCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDTRIDKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTSNNRWVSRSATAQRRKERLRQHSEHVGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNCKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTSASDEDLVKQCRTPPQQKSPTTARRLSITSLTGKNNKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKVVAYFETTDQILDNEDDVLIQKSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDRMTVNSLIRILQTIQDFTIVLEGSLIKGVDV
uniprot
proteins
function
FUNCTION: Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. {ECO:0000269|PubMed:20937701}.
uniprot
proteins
mass_dalton
145020
uniprot
proteins
protein_family
RAB6IP1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20937701
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
1274
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 916..936; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins