Nrbp1
entrez
192292
canonical
uniprot
Q99J45
canonical
ensembl
ENSMUSG00000029148
resolver
ensp
ENSMUSP00000031034
resolver
ensp
ENSMUSP00000143872
resolver
enst
ENSMUST00000031034
resolver
enst
ENSMUST00000202576
resolver
genesymbol
Nrbp1
resolver
genesymbol_syn
Madm
resolver
genesymbol_syn
Nrbp
resolver
uniprot
D3YUV1
resolver
uniprot
Q8BL77
resolver
uniprot_entry
D3YUV1_MOUSE
resolver
uniprot_entry
NRBP_MOUSE
resolver
uniprot_sec
Q8BL77
resolver
amino_acid_sequence
MSEGESQTVVSSGSDPKVESSSLAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDSLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNESIPDLAAELVQLGFISEADQSRLTSLLEETLNKFNFTRNSTLNTATVTVSS
uniprot
proteins
function
FUNCTION: Required for embryonic development (PubMed:22510880). Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes (PubMed:22510880). May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases (By similarity). {ECO:0000250|UniProtKB:Q9UHY1, ECO:0000269|PubMed:22510880}.
uniprot
proteins
mass_dalton
59866
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
Ser/Thr protein kinase family
uniprot
proteins
pubmed
12176995
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22510880
uniprot
proteins
sequence_length
535
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cell cortex {ECO:0000269|PubMed:12176995}. Endomembrane system {ECO:0000269|PubMed:12176995}. Cell projection, lamellipodium {ECO:0000269|PubMed:12176995}. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
uniprot
proteins