PTGFR
entrez
5737
canonical
uniprot
P43088
canonical
ensembl
ENSG00000122420
resolver
ensp
ENSP00000359792
resolver
ensp
ENSP00000359793
resolver
ensp
ENSP00000555154
resolver
genesymbol
PTGFR
resolver
hgnc
HGNC:9600
resolver
uniprot
A8K9Y0
resolver
uniprot
Q2KHP3
resolver
uniprot
Q6RYQ6
resolver
uniprot
Q9P1X4
resolver
uniprot_entry
PF2R_HUMAN
resolver
uniprot_sec
A8K9Y0
resolver
uniprot_sec
Q2KHP3
resolver
uniprot_sec
Q6RYQ6
resolver
uniprot_sec
Q9P1X4
resolver
amino_acid_sequence
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
uniprot
proteins
function
FUNCTION: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. {ECO:0000250, ECO:0000269|PubMed:18587449}.
uniprot
proteins
mass_dalton
40055
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14984197
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
18587449
uniprot
proteins
pubmed
8300593
uniprot
proteins
pubmed
9341156
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 32..54; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 70..90; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 110..131; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 153..175; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 199..224; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 251..267; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 286..307; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins