Tesk2
entrez
230661
canonical
uniprot
Q8VCT9
canonical
ensembl
ENSMUSG00000033985
resolver
ensp
ENSMUSP00000041009
resolver
enst
ENSMUST00000045542
resolver
genesymbol
Tesk2
resolver
uniprot_entry
TESK2_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Activated by autophosphorylation on Ser-219. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MDRSKRNSIAGFPPRVERLEEFEGGGGGDGNTVQVGRVSSSSYRAIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSDLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRLPEEELERDRKLQPTAKGPLEKVPGGKRLSSLDDKIPHKSPRPRRTIWLSRSQSDIFSHKPPRTVSVLDPYYQPRDGATHTPKVNPFSARQDLKGGKVKFFDLPSKSVISLVFDLDAPGPGSTTLADCQEPLAMSSRRWRSLPGSPEFLHQACPFMGCEESLSDGPPPRLSSLKYGVREIPPFRTSALSAASGHEAMDCSNPQEENGFGPRLKGTSLCTGAASEEMEVEEERPRRASVYFSISGISLQTQAKQDG
uniprot
proteins
ec_number
2.7.12.1
uniprot
proteins
function
FUNCTION: Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
63470
uniprot
proteins
protein_family
Protein kinase superfamily
uniprot
proteins
protein_family
TKL Ser/Thr protein kinase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
570
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins