Klra8
entrez
16639
canonical
uniprot
Q60682
canonical
ensembl
ENSMUSG00000089727
resolver
ensp
ENSMUSP00000014476
resolver
ensp
ENSMUSP00000349877
resolver
genesymbol
Klra8
resolver
genesymbol_syn
Ly-49h
resolver
genesymbol_syn
Ly49-h
resolver
genesymbol_syn
Ly49H
resolver
uniprot
O78027
resolver
uniprot
Q3UPS5
resolver
uniprot_entry
KLRA8_MOUSE
resolver
uniprot_entry
Q3UPS5_MOUSE
resolver
uniprot_sec
O78027
resolver
amino_acid_sequence
MSEQEVTFPTMRFHKSSGLNSQVRLEGTQRSRKAGLRVCSVPWQLIVIALGILCSLRLVIVAVFVTKFFQYSQHKQEINETLNHRHNCSNMQRDFNLKEEMLTNKSIDCRPSYELLEYIKREQERWDSETKSVSDSSRDTGRGVKYWFCYGTKCYYFIMNKTTWSGCKANCQHYSVPIVKIEDEDELKFLQRHVILESYWIGLSYDKKKKEWAWIHNGQSKLDMKIKKMNFTSRGCVFLSKARIEDTDCNTPYYCICGKKLDKFPD
uniprot
proteins
function
FUNCTION: Receptor on natural killer (NK) cells for class I MHC. {ECO:0000269|PubMed:9647200}.
uniprot
proteins
mass_dalton
31393
uniprot
proteins
mutagenesis
MUTAGEN 118; /note="Y->A: Partial loss of interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:23666294"; MUTAGEN 123; /note="Q->A: Complete loss of interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:23666294"; MUTAGEN 126; /note="W->A: Complete loss of interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:23666294"; MUTAGEN 131; /note="K->A: No effect on the interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:23666294"; MUTAGEN 146; /note="Y->H: 30% loss of interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:17182575"; MUTAGEN 151; /note="G->S: 35% loss of interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:17182575"; MUTAGEN 179; /note="V->L: 90% loss of interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:17182575"; MUTAGEN 180; /note="K->N: No effect on the interaction Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:17182575"; MUTAGEN 226; /note="I->T: No effect on the interaction with Murid herpesvirus 1 glycoprotein m157."; /evidence="ECO:0000269|PubMed:17182575
uniprot
proteins
pubmed
12060703
uniprot
proteins
pubmed
14597723
uniprot
proteins
pubmed
17182575
uniprot
proteins
pubmed
17537914
uniprot
proteins
pubmed
18566392
uniprot
proteins
pubmed
23666294
uniprot
proteins
pubmed
7964501
uniprot
proteins
pubmed
8824161
uniprot
proteins
pubmed
9647200
uniprot
proteins
sequence_length
266
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 45..66; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins