TEKT2
entrez
27285
canonical
uniprot
Q9UIF3
canonical
ensembl
ENSG00000092850
resolver
ensp
ENSP00000207457
resolver
ensp
ENSP00000572803
resolver
ensp
ENSP00000572804
resolver
ensp
ENSP00000572806
resolver
ensp
ENSP00000592262
resolver
ensp
ENSP00000592263
resolver
enst
ENST00000207457
resolver
enst
ENST00000902744
resolver
enst
ENST00000902745
resolver
enst
ENST00000902747
resolver
enst
ENST00000922203
resolver
enst
ENST00000922204
resolver
genesymbol
TEKT2
resolver
hgnc
HGNC:11725
resolver
uniprot
A6NIS6
resolver
uniprot
O60638
resolver
uniprot_entry
TEKT2_HUMAN
resolver
uniprot_sec
A6NIS6
resolver
uniprot_sec
O60638
resolver
amino_acid_sequence
MATLSVKPSRRFQLPDWHTNSYLLSTNAQLQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLVERIDTVNRWKEMLDKCLTDLDAEIDALTQMKESAEQNLQAKNLPLDVAIECLTLRESRRDIDVVKDPVEDELHKEVEVIEATKKALQQKVSQAFEQLCLLQEVQQQLNSDHRGKMETLEIDRGCLSLNLRSPNISLKVDPTRVPDGSTTLQQWDDFSRFNKDRAEAEMKAATELREATALTIAETNNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLRTKLLSLKLSHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQDALDALCKHLARLQADIACKANSMLLDTKCMDTRRKLTVPAERFVPEVDTFTRTTNSTLSPLKSCQLELA
uniprot
proteins
function
FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:36191189). Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. {ECO:0000250|UniProtKB:Q922G7, ECO:0000269|PubMed:36191189}.
uniprot
proteins
mass_dalton
49672
uniprot
proteins
post_translational_modification
PTM: Tyrosine phosphorylated. {ECO:0000250|UniProtKB:Q1W6C3}.; PTM: Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. {ECO:0000250|UniProtKB:Q922G7}.
uniprot
proteins
protein_family
Tektin family
uniprot
proteins
pubmed
11751288
uniprot
proteins
pubmed
12029069
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
36191189
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:36191189}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q922G7}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q922G7}. Note=Colocalized with CCDC172 at the perinuclear region. {ECO:0000250|UniProtKB:Q922G7}.
uniprot
proteins