Rap2c
entrez
72065
canonical
uniprot
Q8BU31
canonical
ensembl
ENSMUSG00000050029
resolver
ensp
ENSMUSP00000058391
resolver
ensp
ENSMUSP00000224942
resolver
enst
ENSMUST00000053593
resolver
genesymbol
Rap2c
resolver
uniprot
Q504Q0
resolver
uniprot
Q6P1Y7
resolver
uniprot
Q810J4
resolver
uniprot
Q8R2P4
resolver
uniprot_entry
RAP2C_MOUSE
resolver
uniprot_sec
Q504Q0
resolver
uniprot_sec
Q6P1Y7
resolver
uniprot_sec
Q810J4
resolver
uniprot_sec
Q8R2P4
resolver
amino_acid_sequence
MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTCVVQ
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription. {ECO:0000269|PubMed:19061864}.
uniprot
proteins
mass_dalton
20745
uniprot
proteins
mutagenesis
MUTAGEN 176; /note="C->G: Loss of association with the recycling endosome membranes and loss of TNIK activation; when associated with C-177."; /evidence="ECO:0000269|PubMed:19061864"; MUTAGEN 177; /note="C->G: Loss of association with the recycling endosome membranes and loss of TNIK activation; when associated with C-176."; /evidence="ECO:0000269|PubMed:19061864"; MUTAGEN 180; /note="C->A: Loss of association with membranes."; /evidence="ECO:0000269|PubMed:19061864
uniprot
proteins
post_translational_modification
PTM: Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK. {ECO:0000269|PubMed:19061864}.
uniprot
proteins
protein_family
Ras family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19061864
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
183
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Recycling endosome membrane {ECO:0000269|PubMed:19061864}; Lipid-anchor {ECO:0000269|PubMed:19061864}; Cytoplasmic side {ECO:0000269|PubMed:19061864}.
uniprot
proteins