Igsf5
entrez
72058
canonical
uniprot
Q7TSN7
canonical
ensembl
ENSMUSG00000000159
resolver
ensp
ENSMUSP00000000163
resolver
ensp
ENSMUSP00000079874
resolver
ensp
ENSMUSP00000109425
resolver
ensp
ENSMUSP00000288548
resolver
ensp
ENSMUSP00000349414
resolver
ensp
ENSMUSP00000349415
resolver
enst
ENSMUST00000000163
resolver
enst
ENSMUST00000081093
resolver
enst
ENSMUST00000113794
resolver
genesymbol
Igsf5
resolver
genesymbol_syn
Jam4
resolver
uniprot
A0A0B4J1E1
resolver
uniprot
A0A0R4J105
resolver
uniprot
D3YXH1
resolver
uniprot
Q9D8G2
resolver
uniprot_entry
A0A0B4J1E1_MOUSE
resolver
uniprot_entry
A0A0R4J105_MOUSE
resolver
uniprot_entry
D3YXH1_MOUSE
resolver
uniprot_entry
IGSF5_MOUSE
resolver
uniprot_sec
Q9D8G2
resolver
amino_acid_sequence
MEGSWRDVLAVLVILAQLTASGSSYQIIEGPQNVTVLKDSEAHFNCTVTHGWKLLMWTLNQMVVLSLTTQGPIITNNRFTYASYNSTDSFISELIIHDVQPSDSGSVQCSLQNSHGFGSAFLSVQVMGTLNIPSNNLIVTEGEPCNVTCYAVGWTSLPDISWELEVPVSHSSYNSFLESGNFMRVLSVLDLTPLGNGTLTCVAELKDLQASKSLTVNLTVVQPPPDSIGEEGPALPTWAIILLAVAFSLLLILIIVLIIIFCCCCASRREKEESTYQNEIRKSANMRTNKADPETKLKGGKENYGYSSDEAKAAQTASLPPKSAEVSLPEKRSSSLPYQELNKHQPGPATHPRVSFDIASPQKVRNVTLV
uniprot
proteins
function
FUNCTION: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells. {ECO:0000269|PubMed:12773569, ECO:0000269|PubMed:16982697}.
uniprot
proteins
mass_dalton
40292
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:12773569}.
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12773569
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16832352
uniprot
proteins
pubmed
16982697
uniprot
proteins
sequence_length
370
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:Q5VJ70}; Single-pass type I membrane protein {ECO:0000255}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q5VJ70}.
uniprot
proteins
transmembrane_region
TRANSMEM 240..260; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins