Nkap
entrez
298342
canonical
uniprot
Q4V7C9
canonical
ensembl
ENSRNOG00000053813
resolver
ensp
ENSRNOP00000073123
resolver
genesymbol
Nkap
resolver
uniprot_entry
NKAP_RAT
resolver
amino_acid_sequence
MAPVSGSRSPVREASGGKRRSSSRSPKSIKSSRSPRCRRSRSRSCSRFGDRNGLSHSLSGFSQSSRNQSYRSRSRSRSRERPSAQRSAPFASSSSSAYYGGYSRPYGGDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASSSEDDKKKKRKSSRSKERAKKKRKKKSSKRKHKKYSEDSDSDSESDTDSSDEDSKRRAKKAKKKEKKKKRRGKKYKKKKSKKNRKESSDSSSKESQEEFLENPWKDRSKTEEPSDLIGPEAPKTLASQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK
uniprot
proteins
function
FUNCTION: Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter (By similarity). {ECO:0000250|UniProtKB:Q8N5F7}.
uniprot
proteins
mass_dalton
47267
uniprot
proteins
protein_family
NKAP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
415
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins