Nkd1
entrez
93960
canonical
uniprot
Q99MH6
canonical
ensembl
ENSMUSG00000031661
resolver
ensp
ENSMUSP00000034086
resolver
ensp
ENSMUSP00000125935
resolver
ensp
ENSMUSP00000147347
resolver
enst
ENSMUST00000034086
resolver
enst
ENSMUST00000169179
resolver
enst
ENSMUST00000211113
resolver
genesymbol
Nkd1
resolver
uniprot
E9Q5K6
resolver
uniprot
Q3TLD6
resolver
uniprot
Q8K200
resolver
uniprot
Q91Y46
resolver
uniprot_entry
E9Q5K6_MOUSE
resolver
uniprot_entry
NKD1_MOUSE
resolver
uniprot_sec
Q3TLD6
resolver
uniprot_sec
Q8K200
resolver
uniprot_sec
Q91Y46
resolver
amino_acid_sequence
MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGSVSGPRQLRLAGTVGRGTRELVGDTSREALGEEDEDDFPLEVALPPEKIDSLGSGDEKRMERLSEPGQASKKQLKFEELQCDVSVEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKTLRVKLTVAPDGSQSKRSVLFNHTDLQSTRPRADTKPAEELRGWEKKQRAPLRFQGDSHLEQPDCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRISNPTRSRSHEPEAAHIPHRRPQGVDPGSFHLLDTPFAKASELQQRLRGTQDGSKHFVRSPKAQGKNMGMGHGARGARSKPPLVPTTHTVSPSAHLATSPALLPTLAPLGHKKHKHRAKESQASCRGLQGPLAAGGSTVMGREQVRELPAVVVYESQAGQAVQRHEHHHHHEHHHHYHHFYQP
uniprot
proteins
function
FUNCTION: Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for spermatogenesis. {ECO:0000269|PubMed:11274398, ECO:0000269|PubMed:11356022, ECO:0000269|PubMed:15546883}.
uniprot
proteins
mass_dalton
52391
uniprot
proteins
mutagenesis
MUTAGEN 138..163; /note="Missing: Impairs inhibition of the Wnt signaling pathway."; /evidence="ECO:0000269|PubMed:11274398"; MUTAGEN 144; /note="D->V: Impairs inhibition of the Wnt signaling pathway; when associated with V-146."; /evidence="ECO:0000269|PubMed:11274398"; MUTAGEN 146; /note="D->V: Impairs inhibition of the Wnt signaling pathway; when associated with V-144."; /evidence="ECO:0000269|PubMed:11274398"; MUTAGEN 149; /note="G->W: Impairs inhibition of the Wnt signaling pathway."; /evidence="ECO:0000269|PubMed:11274398
uniprot
proteins
protein_family
NKD family
uniprot
proteins
pubmed
11274398
uniprot
proteins
pubmed
11356022
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15511637
uniprot
proteins
pubmed
15546883
uniprot
proteins
pubmed
15687260
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16488995
uniprot
proteins
pubmed
17438140
uniprot
proteins
sequence_length
471
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}. Cytoplasm {ECO:0000250}.
uniprot
proteins