Nol7
entrez
70078
canonical
uniprot
Q9D7Z3
canonical
ensembl
ENSMUSG00000063200
resolver
ensp
ENSMUSP00000071818
resolver
genesymbol
Nol7
resolver
uniprot
A1L3B6
resolver
uniprot
Q9CY79
resolver
uniprot
Q9JJE2
resolver
uniprot_entry
A1L3B6_MOUSE
resolver
uniprot_entry
UTP16_MOUSE
resolver
uniprot_sec
Q9CY79
resolver
uniprot_sec
Q9JJE2
resolver
amino_acid_sequence
MVQLRPRLSRIPAPAEAMVDEDQAASEEEEAEHGLLLAQPSSGAAAEPLDEEEDADDEAPEELTFASAQAEAREEELRVRASARRDKTLLKEKRKRREELFIEQKKRKLLPDAVLEQLTTASEADIKKSPENVKVNLKKKSEQHAKGRNSKKVKVQKVQSVGQIESYMAVRLKDEDLRDSRQEAAKHFIHSCLYGSDSKRTTVNKFLSLNNKRSPVKKAAAQFLTSTWGAQKQQNAKRFKKRWMAKKMKKKTYK
uniprot
proteins
function
FUNCTION: Functions as part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit that coordinates the first two steps of ribosome biogenesis in transcription of the primary transcript pre-RNA and pre-18S processing. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. This subunit is required for processing of the 5'-external transcribed spacer sequence (5'ETS) of the primary transcript pre-rRNA to yield the 18S rRNA. Also plays a role in maintaining early pre-rRNA levels, either by assisting in its transcription or stability. {ECO:0000250|UniProtKB:Q9UMY1}.
uniprot
proteins
mass_dalton
28970
uniprot
proteins
protein_family
UTP16 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
254
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9UMY1}.
uniprot
proteins