TRIM60
entrez
166655
canonical
uniprot
Q495X7
canonical
ensembl
ENSG00000176979
resolver
ensp
ENSP00000343765
resolver
ensp
ENSP00000421142
resolver
ensp
ENSP00000426496
resolver
ensp
ENSP00000497401
resolver
enst
ENST00000341062
resolver
enst
ENST00000508504
resolver
enst
ENST00000512596
resolver
enst
ENST00000647760
resolver
genesymbol
TRIM60
resolver
genesymbol_syn
RNF129
resolver
genesymbol_syn
RNF33
resolver
hgnc
HGNC:21162
resolver
uniprot
Q8NA35
resolver
uniprot_entry
TRI60_HUMAN
resolver
uniprot_sec
Q8NA35
resolver
amino_acid_sequence
MEFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPFQVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYFYTGTDSEPLKICSVSDSER
uniprot
proteins
function
FUNCTION: E3 SUMO-protein ligase that mediates SUMOylation of TAB2 leading to inhibition of NF-kappa-B and MAPK pathways by suppressing the TRAF6/TAB2/TAK1 complex. {ECO:0000269|PubMed:33184450}.
uniprot
proteins
mass_dalton
55114
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
33184450
uniprot
proteins
sequence_length
471
uniprot
proteins