Hmox2
entrez
79239
canonical
uniprot
P23711
canonical
ensembl
ENSRNOG00000003773
resolver
ensembl
ENSRNOG00055028051
resolver
ensembl
ENSRNOG00060007820
resolver
ensembl
ENSRNOG00065010283
resolver
ensp
ENSRNOP00000075102
resolver
ensp
ENSRNOP00000084166
resolver
ensp
ENSRNOP00055039913
resolver
ensp
ENSRNOP00060009780
resolver
ensp
ENSRNOP00065012651
resolver
enst
ENSRNOT00000077164
resolver
enst
ENSRNOT00055048553
resolver
enst
ENSRNOT00060012904
resolver
enst
ENSRNOT00065016608
resolver
genesymbol
Hmox2
resolver
uniprot_entry
HMOX2_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by metalloporphyrins such as Sn- and Zn-protoporphyrins. {ECO:0000269|PubMed:1575508}.
uniprot
proteins
amino_acid_sequence
MSSEVETSEGVDESENNSTAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALIKDMEYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLSMKTKERIVEEANKAFEYNMQIFSELDQAGSMLTKETLEDGLPVHDGKGDVRKCPFYAAQPDKGTLGGSNCPFRTAMAVLRKPSLQLILAASVALVAGLLAWYYM
uniprot
proteins
ec_number
1.14.14.18
uniprot
proteins
function
FUNCTION: [Heme oxygenase 2]: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. {ECO:0000269|PubMed:1575508, ECO:0000269|PubMed:2185251}.; FUNCTION: [Heme oxygenase 2 soluble form]: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. {ECO:0000250|UniProtKB:P30519}.
uniprot
proteins
mass_dalton
35762
uniprot
proteins
post_translational_modification
PTM: A soluble form arises by proteolytic removal of the membrane anchor. {ECO:0000250|UniProtKB:P30519}.; PTM: S-nitrosylated by BLVRB. {ECO:0000250|UniProtKB:P30519}.
uniprot
proteins
protein_family
Heme oxygenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1575508
uniprot
proteins
pubmed
2185251
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
3343248
uniprot
proteins
pubmed
8112599
uniprot
proteins
sequence_length
315
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Microsome membrane {ECO:0000250|UniProtKB:P30519}; Single-pass type IV membrane protein {ECO:0000255}; Cytoplasmic side {ECO:0000250|UniProtKB:P09601}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P09601}; Single-pass type IV membrane protein {ECO:0000255}; Cytoplasmic side {ECO:0000250|UniProtKB:P09601}.
uniprot
proteins
transmembrane_region
TRANSMEM 295..315; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins