SPDEF
entrez
25803
canonical
uniprot
O95238
canonical
ensembl
ENSG00000124664
resolver
ensp
ENSP00000363149
resolver
ensp
ENSP00000442715
resolver
genesymbol
SPDEF
resolver
genesymbol_syn
PDEF
resolver
genesymbol_syn
PSE
resolver
hgnc
HGNC:17257
resolver
uniprot
B4DWH8
resolver
uniprot
F5H778
resolver
uniprot_entry
SPDEF_HUMAN
resolver
uniprot_sec
B4DWH8
resolver
uniprot_sec
F5H778
resolver
amino_acid_sequence
MGSASPGLSSVSPSHLLLPPDTVSRTGLEKAAAGAVGLERRDWSPSPPATPEQGLSAFYLSYFDMLYPEDSSWAAKAPGASSREEPPEEPEQCPVIDSQAPAGSLDLVPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAGKELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI
uniprot
proteins
function
FUNCTION: May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter. {ECO:0000269|PubMed:10625666}.
uniprot
proteins
mass_dalton
37518
uniprot
proteins
protein_family
ETS family
uniprot
proteins
pubmed
10625666
uniprot
proteins
pubmed
10675039
uniprot
proteins
pubmed
11809674
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15882048
uniprot
proteins
sequence_length
335
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins