Stxbp2
entrez
20911
canonical
uniprot
Q64324
canonical
ensembl
ENSMUSG00000004626
resolver
ensp
ENSMUSP00000004745
resolver
ensp
ENSMUSP00000125405
resolver
ensp
ENSMUSP00000231462
resolver
ensp
ENSMUSP00000231465
resolver
ensp
ENSMUSP00000231482
resolver
ensp
ENSMUSP00000338494
resolver
enst
ENSMUST00000004745
resolver
enst
ENSMUST00000160708
resolver
genesymbol
Stxbp2
resolver
genesymbol_syn
Unc18b
resolver
uniprot
F8WGM5
resolver
uniprot
Q548T0
resolver
uniprot_entry
F8WGM5_MOUSE
resolver
uniprot_entry
Q548T0_MOUSE
resolver
uniprot_entry
STXB2_MOUSE
resolver
amino_acid_sequence
MAPLGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKRREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRLAKAVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAGERGRQLDALAQQIATLCATLQEYPSIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLDIEQDTYRYETTGLSESREKAVLLDEDDDLWVELRHMHIADVSKKVTELLKTFCESKRLTTDKANIKDLSHILKKMPQYQKELNKYSTHLHLADDCMKHFKGSVEKLCSVEQDLAMGSDAEGEKIKDAMKLIVPVLLDASVPPYDKIRVLLLYILLRNGVSEENLAKLIQHANVQSYSSLIRNLEQLGGTVTNSAGSGTSSRLERRERMEPTYQLSRWSPVIKDVMEDVVEDRLDRKLWPFVSDPAPVPSSQAAVSARFGHWHKNKAGVEARAGPRLIVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKTLDQKLEGVALP
uniprot
proteins
function
FUNCTION: Functions in intracellular vesicle trafficking through interaction with SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) which are essential proteins for membrane fusion. By promoting the assembly of functional STX11/SNAP23/VAMP8 SNARE complexes at the plasma membrane, regulates cytotoxic granule exocytosis in natural killer (NK) cells. {ECO:0000250|UniProtKB:Q15833}.
uniprot
proteins
mass_dalton
66357
uniprot
proteins
protein_family
STXBP/unc-18/SEC1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7890599
uniprot
proteins
pubmed
7890715
uniprot
proteins
sequence_length
593
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q15833}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q15833}. Cytolytic granule membrane {ECO:0000250|UniProtKB:Q15833}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q15833}. Note=Enriched at the immunological synapse in activated immune cells. {ECO:0000250|UniProtKB:Q15833}.
uniprot
proteins