SULT1C3
entrez
442038
canonical
uniprot
Q6IMI6
canonical
ensembl
ENSG00000196228
resolver
ensp
ENSP00000333310
resolver
ensp
ENSP00000505748
resolver
genesymbol
SULT1C3
resolver
hgnc
HGNC:33543
resolver
uniprot
Q6IMI5
resolver
uniprot_entry
ST1C3_HUMAN
resolver
uniprot_sec
Q6IMI5
resolver
amino_acid_sequence
MAKIEKNAPTMEKKPELFNIMEVDGVPTLILSKEWWEKVCNFQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQTLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHSISPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTFRTEI
uniprot
proteins
ec_number
2.8.2.1
uniprot
proteins
ec_number
2.8.2.2
uniprot
proteins
function
FUNCTION: [Isoform 1]: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor. Has sulfotransferase activity towards various substrates, such as bile acids, thyroid hormones and toward xenobiotic compounds such as chloro phenols and hydroxypyrenes. Lithocholic acid appears to be the best substrate among the endogenous compounds tested and 3,3',5,5'-tetrachloro-4,4'-biphenyldiol shows the highest specific activity among the xenobiotic compounds. {ECO:0000269|PubMed:17425406, ECO:0000269|PubMed:17936463, ECO:0000269|PubMed:28992322}.; FUNCTION: [Isoform 2]: Exhibits weak sulphating activity and only toward chloro phenols (pentachlorophenol and 3,3',5,5'-tetrachloro-4,4'-biphenyldiol). {ECO:0000269|PubMed:28992322}.
uniprot
proteins
mass_dalton
35889
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
14676822
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17425406
uniprot
proteins
pubmed
17936463
uniprot
proteins
pubmed
24335392
uniprot
proteins
pubmed
28992322
uniprot
proteins
sequence_length
304
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q80VR3}.
uniprot
proteins