NTNG2
entrez
84628
canonical
uniprot
Q96CW9
canonical
ensembl
ENSG00000196358
resolver
ensp
ENSP00000376921
resolver
ensp
ENSP00000616547
resolver
ensp
ENSP00000616551
resolver
genesymbol
NTNG2
resolver
genesymbol_syn
KIAA1857
resolver
genesymbol_syn
LMNT2
resolver
hgnc
HGNC:14288
resolver
uniprot
Q5JUJ2
resolver
uniprot
Q6UXY0
resolver
uniprot
Q96JH0
resolver
uniprot_entry
NTNG2_HUMAN
resolver
uniprot_sec
Q5JUJ2
resolver
uniprot_sec
Q6UXY0
resolver
uniprot_sec
Q96JH0
resolver
amino_acid_sequence
MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR
uniprot
proteins
disease_involvement
DISEASE: Neurodevelopmental disorder with behavioral abnormalities, absent speech, and hypotonia (NEDBASH) [MIM:618718]: An autosomal recessive disorder characterized by global developmental delay with severely impaired intellectual development, impaired motor development, axial and peripheral hypotonia, poor speech and significant behavioral abnormalities, including autism spectrum disorder, hyperactivity, mood disorders, aggression, hand and face stereotypies, sleep disturbances, anxiety, self-injurious behavior, and bruxism. {ECO:0000269|PubMed:31372774, ECO:0000269|PubMed:31668703, ECO:0000269|PubMed:31692205}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites. {ECO:0000269|PubMed:21946559}.
uniprot
proteins
mass_dalton
59799
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q8R4F1}.
uniprot
proteins
pubmed
11347906
uniprot
proteins
pubmed
12168954
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21946559
uniprot
proteins
pubmed
22041449
uniprot
proteins
pubmed
31372774
uniprot
proteins
pubmed
31668703
uniprot
proteins
pubmed
31692205
uniprot
proteins
sequence_length
530
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:21946559, ECO:0000269|PubMed:31668703}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:21946559}; Extracellular side {ECO:0000269|PubMed:21946559, ECO:0000269|PubMed:31668703}.
uniprot
proteins