Entpd6
entrez
85260
canonical
uniprot
Q9ER31
canonical
ensembl
ENSRNOG00000007427
resolver
ensembl
ENSRNOG00055023532
resolver
ensembl
ENSRNOG00060001847
resolver
ensp
ENSRNOP00000009946
resolver
ensp
ENSRNOP00055032861
resolver
ensp
ENSRNOP00060001849
resolver
enst
ENSRNOT00000009946
resolver
enst
ENSRNOT00055040450
resolver
enst
ENSRNOT00060002839
resolver
genesymbol
Entpd6
resolver
genesymbol_syn
Cd39l2
resolver
uniprot_entry
ENTP6_RAT
resolver
amino_acid_sequence
MRKIPNHGTLRMTKVAYPLGLCVGLFIYVAYIKWHRASAAQAFFTIAGAASGVRWTQQAFSSPDSATRGHEVFYGIMFDAGSTGTRIHVFQFARPPGETPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDEGVSAWITVNFLTGSLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDDKELVSPCLSPRFRGKWEHAEVTYRISGQKAVGLYELCASRVSEVLRNKVHRTEEAQHVDFYAFSYYYDLAASFGLIDAEKGGSLVVGDFEIAAKYVCRTLETQPPSSPFACMDLTYISLLLHEFGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL
uniprot
proteins
ec_number
3.6.1.6
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP (PubMed:11042118). The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides (PubMed:11042118). {ECO:0000269|PubMed:11042118}.
uniprot
proteins
mass_dalton
49899
uniprot
proteins
post_translational_modification
PTM: Might be cleaved at the N-terminus, retained in an intracellular membrane compartment and in addition be released into the extracellular medium. {ECO:0000269|PubMed:11042118}.; PTM: N-glycosylated. {ECO:0000250|UniProtKB:O75354}.
uniprot
proteins
protein_family
GDA1/CD39 NTPase family
uniprot
proteins
pubmed
11042118
uniprot
proteins
sequence_length
455
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:11042118}; Single-pass type II membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:11042118}. Cell membrane {ECO:0000269|PubMed:11042118}; Single-pass type II membrane protein {ECO:0000255}. Note=Exists as a secreted and membrane-bound forms in the medium of transfected cells, the secreted form is predominant. {ECO:0000269|PubMed:11042118}.
uniprot
proteins
transmembrane_region
TRANSMEM 13..32; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins