KCNJ15
entrez
3772
canonical
uniprot
Q99712
canonical
ensembl
ENSG00000157551
resolver
ensp
ENSP00000331698
resolver
ensp
ENSP00000381904
resolver
ensp
ENSP00000381905
resolver
ensp
ENSP00000381907
resolver
ensp
ENSP00000381911
resolver
ensp
ENSP00000479100
resolver
ensp
ENSP00000484960
resolver
ensp
ENSP00000536407
resolver
ensp
ENSP00000536408
resolver
ensp
ENSP00000536409
resolver
ensp
ENSP00000536410
resolver
ensp
ENSP00000536411
resolver
ensp
ENSP00000536412
resolver
ensp
ENSP00000536413
resolver
ensp
ENSP00000536414
resolver
ensp
ENSP00000536415
resolver
ensp
ENSP00000536416
resolver
ensp
ENSP00000536417
resolver
ensp
ENSP00000536418
resolver
ensp
ENSP00000536419
resolver
ensp
ENSP00000536420
resolver
ensp
ENSP00000623680
resolver
ensp
ENSP00000623681
resolver
ensp
ENSP00000623682
resolver
ensp
ENSP00000623683
resolver
ensp
ENSP00000623684
resolver
ensp
ENSP00000623685
resolver
ensp
ENSP00000623686
resolver
ensp
ENSP00000623687
resolver
ensp
ENSP00000623688
resolver
ensp
ENSP00000623689
resolver
enst
ENST00000328656
resolver
enst
ENST00000398930
resolver
enst
ENST00000398932
resolver
enst
ENST00000398934
resolver
enst
ENST00000398938
resolver
enst
ENST00000612702
resolver
enst
ENST00000613499
resolver
enst
ENST00000866348
resolver
enst
ENST00000866349
resolver
enst
ENST00000866350
resolver
enst
ENST00000866351
resolver
enst
ENST00000866352
resolver
enst
ENST00000866353
resolver
enst
ENST00000866354
resolver
enst
ENST00000866355
resolver
enst
ENST00000866356
resolver
enst
ENST00000866357
resolver
enst
ENST00000866358
resolver
enst
ENST00000866359
resolver
enst
ENST00000866360
resolver
enst
ENST00000866361
resolver
enst
ENST00000953621
resolver
enst
ENST00000953622
resolver
enst
ENST00000953623
resolver
enst
ENST00000953624
resolver
enst
ENST00000953625
resolver
enst
ENST00000953626
resolver
enst
ENST00000953627
resolver
enst
ENST00000953628
resolver
enst
ENST00000953629
resolver
enst
ENST00000953630
resolver
genesymbol
KCNJ15
resolver
genesymbol_syn
KCNJ14
resolver
hgnc
HGNC:6261
resolver
uniprot
D3DSH5
resolver
uniprot
O00564
resolver
uniprot
Q96L28
resolver
uniprot
Q99446
resolver
uniprot_entry
KCJ15_HUMAN
resolver
uniprot_sec
D3DSH5
resolver
uniprot_sec
O00564
resolver
uniprot_sec
Q96L28
resolver
uniprot_sec
Q99446
resolver
activity_regulation
ACTIVITY REGULATION: Channel activity is regulated by variations of cytosolic pH; reversibly inhibited by acidic pH values. Inhibited by Ba(2+) and Cs(+) in a voltage-dependent manner. {ECO:0000250|UniProtKB:O88932}.
uniprot
proteins
amino_acid_sequence
MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQSNV
uniprot
proteins
function
FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. {ECO:0000250|UniProtKB:O88932}.
uniprot
proteins
mass_dalton
42577
uniprot
proteins
protein_family
Inward rectifier-type potassium channel (TC 1.A.2.1) family
uniprot
proteins
protein_family
KCNJ15 subfamily
uniprot
proteins
pubmed
10830953
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
8995301
uniprot
proteins
pubmed
9299242
uniprot
proteins
pubmed
9647694
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q91ZF1}.
uniprot
proteins
transmembrane_region
TRANSMEM 61..87; /note="Helical; Name=M1"; /evidence="ECO:0000250|UniProtKB:P49655"; TRANSMEM 140..165; /note="Helical; Name=M2"; /evidence="ECO:0000250|UniProtKB:P49655
uniprot
proteins