Naf1
entrez
234344
canonical
uniprot
Q3UMQ8
canonical
ensembl
ENSMUSG00000014907
resolver
ensp
ENSMUSP00000112640
resolver
enst
ENSMUST00000118009
resolver
genesymbol
Naf1
resolver
uniprot
E9QJT2
resolver
uniprot
Q8R2W2
resolver
uniprot_entry
E9QJT2_MOUSE
resolver
uniprot_entry
NAF1_MOUSE
resolver
uniprot_sec
Q8R2W2
resolver
amino_acid_sequence
MEVVEAAAQLQTLKFGGSGQGSAAPQPPEDRREAPPPGVQPPPPAPSGRPPPPPAPSSDPGGRPPPPPAPNWDAGGRPPPPPAPNSDPPPGGAWVTGRNAAEPPPVLQASDSSDSDSDSETDSDSSSSSSSSSSSSSSCVSFPPVLSDGDEDFQLEKENKNFPLKTKDELLLNELPSVEELTVILPEDIALKPLGKVSSIIEQLVIIESVTNIPPVNEDTVIFKSDRQAAGKIFEIFGPVAHPFYVLRFNSSDHIESKGIKINDTMYFAPSMKDFTQYIFTEKLKQDRGSDASWKNDQEPPPEVLDFSDDEKEKEAKQRKKSQIQGRKKLKSELNESGEDFGEVHENWNAYSSSEHSKGYHHREFSRGFARGRYSRRSHGRPPPQQYYNSDHMASQESLGFTPQRQDNPVMPHYPFPPPMFDMHNFPLPPPPPPPPPPPPSMGWAAPSMASHPVLNLPYSMPPPPLPPPPPPPPPSPGENNSSHFGPYF
uniprot
proteins
function
FUNCTION: RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. {ECO:0000269|PubMed:27510903}.
uniprot
proteins
mass_dalton
53246
uniprot
proteins
protein_family
NAF1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27510903
uniprot
proteins
sequence_length
489
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P53919}. Nucleus {ECO:0000250|UniProtKB:P53919}. Note=Shuttles between the cytoplasm and the nucleus. Absent from the nucleolus (By similarity). {ECO:0000250|UniProtKB:P53919}.
uniprot
proteins