Fhod1
entrez
234686
canonical
uniprot
Q6P9Q4
canonical
ensembl
ENSMUSG00000014778
resolver
ensp
ENSMUSP00000014922
resolver
ensp
ENSMUSP00000256878
resolver
enst
ENSMUST00000014922
resolver
genesymbol
Fhod1
resolver
genesymbol_syn
Fhos1
resolver
uniprot
Q8BMK2
resolver
uniprot_entry
FHOD1_MOUSE
resolver
uniprot_sec
Q8BMK2
resolver
amino_acid_sequence
MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSAQIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYGSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIQAVNAVASATGTLPWANLVSILEEKNGADAELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLEDGDMEEAAAAAAAGGRRERRKPSSEEGKRSRRSLEGGGCPVRAPEPGSTGSASPVGSTPSTGSAPPTNPAFSSTGPASGLLRTSVNLFPTISVGPSVDSSCERSVYKARFLENVAAAETEKQAALAQGRAETLAGATVDDTDGSSGTRELWDSPEPASAPRTPQSPVSRILLRTQRSLEPEPKKPVSPPSPKAEPIQEPPTCVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKASPFLSSLSPSLSGGPPPPPPPPPPITGSCPPPPPPPLPPPATGSCPPPPPPPPPPIIGSCPPPPPLAAPFTHSALDGPRHPTKRKTVKLFWRELKLTGGPGCSRSRFGPCPTLWASLEPVSVDTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGPAENFLMTLASIGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLYHLCSLVLQTRPDSSDLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSPALRARLTHFLAQCTRRVAMLRVVHRRVCNRFHAFLLYLGYTPQAARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERNKTRGRMITETEKFSGVAGEAPNNLSVPVAVGSGPGQGDTDNHASMKSLLTSRPEDATHSRRSRGMVQSSSPVSHTAVGPSAASPEETAASGLPTDTSDEIMDLLVQSVTKSGPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAPGLEV
uniprot
proteins
function
FUNCTION: Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
129600
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by ROCK1. {ECO:0000250}.
uniprot
proteins
protein_family
Formin homology family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15966898
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1197
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, bleb {ECO:0000250}. Note=Predominantly cytoplasmic. {ECO:0000250}.
uniprot
proteins