Q3UTQ7
uniprot
Q3UTQ7
canonical
amino_acid_sequence
MDPKDESAHVWPTSADHEQSTAQVHFVPDAGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPAQVAYVQQDATAQQVLPSIESVHGSDPLATLQNPIARLDAKEEEEEEEDEDEDTEEEEEEDAEDTDVDDWQPDPPRPFDPHDLWCEECNNAHSSVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKDRDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFTRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQASIPIPQLPQETPPSLEQEPETHTLHLQPQQEESLVPTQTTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSASLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHVNDGCFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKNEMSYFALSKKVALYIAFMVKYLTLQVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEYAQLPNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVAPATSPHQSQQSTVDVGQLHDPQTYTQHAIQVQHIQVTEPAPAAPSASQVAGQPLSPSAQQVQQGLSPSHIQGSSSTQGQALQQQQNSSVQHTYLPNAWNSFRGYSAVSAGDTSHESASEIQMMTLPPGQFVITDSGVATPVTSGQVKAVTPGHYVLSESQPELEEKQASALSGAVQVQPSAHSDSLDSTGPSQQQTTQYIITTTTNGNGGSEVHITKP
uniprot
proteins
function
FUNCTION: Transcriptional activator, essential for early embryonic development and survival of embryonic stem cells (ESCs) (PubMed:32681107). Supports cell growth and survival during early development by transcriptionally activating the expression of the translation initiation factor EIF3B, to sustain global translation (PubMed:32681107). Activates the transcription of FLNC (By similarity). {ECO:0000250|UniProtKB:Q9NQV6, ECO:0000269|PubMed:32681107}.
uniprot
proteins
mass_dalton
133746
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
pubmed
12175877
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
32681107
uniprot
proteins
sequence_length
1184
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9NQV6}.
uniprot
proteins