GSTM1
entrez
2944
canonical
uniprot
P09488
canonical
ensembl
ENSG00000134184
resolver
ensp
ENSP00000234981
resolver
ensp
ENSP00000311469
resolver
genesymbol
GSTM1
resolver
genesymbol_syn
GST1
resolver
hgnc
HGNC:4632
resolver
uniprot
Q5GHG0
resolver
uniprot
Q6FH88
resolver
uniprot
Q8TC98
resolver
uniprot
Q9UC96
resolver
uniprot
X5D932
resolver
uniprot
X5DR03
resolver
uniprot_entry
GSTM1_HUMAN
resolver
uniprot_entry
X5D932_HUMAN
resolver
uniprot_entry
X5DR03_HUMAN
resolver
uniprot_sec
Q5GHG0
resolver
uniprot_sec
Q6FH88
resolver
uniprot_sec
Q8TC98
resolver
uniprot_sec
Q9UC96
resolver
amino_acid_sequence
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
uniprot
proteins
ec_number
2.5.1.18
uniprot
proteins
function
FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). {ECO:0000269|PubMed:16548513, ECO:0000269|PubMed:21046276, ECO:0000269|PubMed:9084911}.
uniprot
proteins
mass_dalton
25712
uniprot
proteins
mutagenesis
MUTAGEN 7; /note="Y->F: Reduces catalytic activity 100-fold."; /evidence="ECO:0000269|PubMed:16548513"; MUTAGEN 108; /note="H->Q: Reduces catalytic activity by half."; /evidence="ECO:0000269|PubMed:16548513, ECO:0000269|PubMed:9930979"; MUTAGEN 108; /note="H->S: Changes the properties of the enzyme toward some substrates."; /evidence="ECO:0000269|PubMed:16548513, ECO:0000269|PubMed:9930979"; MUTAGEN 109; /note="M->I: Reduces catalytic activity by half."; /evidence="ECO:0000269|PubMed:16548513"; MUTAGEN 116; /note="Y->A: Reduces catalytic activity 10-fold."; /evidence="ECO:0000269|PubMed:16548513"; MUTAGEN 116; /note="Y->F: Slight increase of catalytic activity."; /evidence="ECO:0000269|PubMed:16548513
uniprot
proteins
protein_family
GST superfamily
uniprot
proteins
protein_family
Mu family
uniprot
proteins
pubmed
11271497
uniprot
proteins
pubmed
1420361
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16548513
uniprot
proteins
pubmed
1846734
uniprot
proteins
pubmed
21046276
uniprot
proteins
pubmed
2110160
uniprot
proteins
pubmed
2362832
uniprot
proteins
pubmed
3174634
uniprot
proteins
pubmed
3419925
uniprot
proteins
pubmed
3864155
uniprot
proteins
pubmed
3979555
uniprot
proteins
pubmed
7822249
uniprot
proteins
pubmed
8317488
uniprot
proteins
pubmed
8471052
uniprot
proteins
pubmed
9084911
uniprot
proteins
pubmed
9930979
uniprot
proteins
sequence_length
218
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins