Kif24
entrez
109242
canonical
uniprot
Q6NWW5
canonical
ensembl
ENSMUSG00000028438
resolver
ensp
ENSMUSP00000030148
resolver
ensp
ENSMUSP00000103690
resolver
genesymbol
Kif24
resolver
uniprot
A2BGK6
resolver
uniprot
Q8BUI2
resolver
uniprot
Q99PT7
resolver
uniprot_entry
KIF24_MOUSE
resolver
uniprot_sec
A2BGK6
resolver
uniprot_sec
Q8BUI2
resolver
uniprot_sec
Q99PT7
resolver
amino_acid_sequence
MASWLYECLCEAELAQYYPHFTALGLQKIDELAKVTMKDYSRLGVHDMNDRKRLFQLIKIIKIMQEEDKALGIPEHPLQASSLYTKPREFRSGPRRQLHFDSPSASKDKMANNETGSLSNFSVDEQKSTYLKVLEHMLPDDSQCQTKIRAPDASAADASMQTETNAPLFSSNYFSPQLGNCDIPVIQRVSHVSGYNYGIPHSCVRQITSENPWTEMEKIRVCVRKRPLGVREVRRGEVNVITVEDKETLLVHEKKEAVDLTQYILQHVFYFDEVFGEACSNQDVYLKTAHPLIQHIFNGGSATCFAYGQTGAGKTYTMIGTHQNPGLYALAAKDIFRQLKVSQSRRNLFVWISFYEIYCGQLYDLLNRRKRLFAREDSKHVVQIAGLRELQVDSVELLLQVILKGSKERSTGATGVNADSSRSHAIIQIQIKDSAKRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHTHTPFRQSKLTQVLKDSFIGNAKTCMIANISPSHIATEHTLNTLRYADRVKELKKGVKCCASATSQNQTSANASPKRIQSSPVTLPGDKCSPKKVKLGLQQSLTVAPGPTKVKAHPLASHVPNVPFTSGPKTPGKKSSSRGSPTPEWDMKASPRKGTTRSGHSIKKGAESAPLCSEKSQIGSKIAVGWEGRASDPGEGLLRVRLPTRGKKVQPVQPVQKQLLSRPRLLANSHHLEATQDSKVGTPAGLAPEAWTNPILQQKEREEHLRFYHQQFQQPPLLKQKLNYQPLQRLLCQHRPSEGRLQSETGFPLHSNPENRDGAQAEDLDDSDFSEDSFSHGSSQPAMKQGSTALERSGSSFFLHQDREHSPEEQAAERQQCLLFSSETDGSKKRPADSWVYSRDPIISHRRGALSQSHSPSMVCPDWSKEEDSASSGPSPKDNRAQKPSSSQVDFVHHQKPGEAQVSDIRLEAFTSEVPEQAEGSLSSPSPENGLSFPLSHVAVSGSPDQRDRVCTPLREVSENRVTHTPGRVNSSTPFQEDSGEQIQMCSANASGLMAPLTMSLLETPCHEDLSSLEQIAQDGAGYGFMAEIVGGPAAGHTVPSYDQEAALPVSSATECLWLSSSPPDNRPSGDLPALSPSPIHQHSPDKLPGREAYQTRRPILLPENHMGSKLYDDRAEETELGGSLTFPRKPSSNIHAGVPYSTPFLTSCTGSSNGVGRPWAQERKHPTGVSCQELVSSTDSNKPHYNEDIAWLRHRPISRCLDSDSPVVPSCSSKALRTYCPLTPEQAQQVIIRAHKEQLDEMAELDLKEETLMTQMDSNDFEDFVTQLDEIMALKSRCIQSLRSQLQLYLTSHRPAAAPERTVVS
uniprot
proteins
function
FUNCTION: Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. Following activation by NEK2 involved in disassembly of primary cilium during G2/M phase but does not disassemble fully formed ciliary axonemes. As cilium assembly and disassembly is proposed to coexist in a dynamic equilibrium may suppress nascent cilium assembly and, potentially, ciliar re-assembly in cells that have already disassembled their cilia ensuring the completion of cilium removal in the later stages of the cell cycle (By similarity). Plays an important role in recruiting MPHOSPH9, a negative regulator of cilia formation to the distal end of mother centriole (By similarity). {ECO:0000250|UniProtKB:Q5T7B8}.
uniprot
proteins
mass_dalton
150207
uniprot
proteins
protein_family
Kinesin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
11416179
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q5T7B8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q5T7B8}. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole. {ECO:0000250|UniProtKB:Q5T7B8}.
uniprot
proteins