ATF3
entrez
467
canonical
uniprot
P18847
canonical
ensembl
ENSG00000162772
resolver
ensp
ENSP00000336908
resolver
ensp
ENSP00000344352
resolver
ensp
ENSP00000355950
resolver
ensp
ENSP00000355954
resolver
ensp
ENSP00000480606
resolver
ensp
ENSP00000542962
resolver
genesymbol
ATF3
resolver
hgnc
HGNC:785
resolver
uniprot
Q5VTZ2
resolver
uniprot
Q6ICQ9
resolver
uniprot
Q7Z566
resolver
uniprot
Q8WYM6
resolver
uniprot_entry
ATF3_HUMAN
resolver
uniprot_sec
Q5VTZ2
resolver
uniprot_sec
Q6ICQ9
resolver
uniprot_sec
Q7Z566
resolver
uniprot_sec
Q8WYM6
resolver
amino_acid_sequence
MMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQS
uniprot
proteins
function
FUNCTION: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. {ECO:0000269|PubMed:7515060}.; FUNCTION: [Isoform 2]: Activates transcription presumably by sequestering inhibitory cofactors away from the promoters. {ECO:0000269|PubMed:7515060}.; FUNCTION: [Isoform 3]: Stress-induced isoform, counteracts the transcriptional repression of isoform 1. {ECO:0000269|PubMed:12034827}.
uniprot
proteins
mass_dalton
20576
uniprot
proteins
protein_family
ATF subfamily
uniprot
proteins
protein_family
BZIP family
uniprot
proteins
pubmed
12034827
uniprot
proteins
pubmed
12881527
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14759258
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
2516827
uniprot
proteins
pubmed
25865756
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
29463886
uniprot
proteins
pubmed
7515060
uniprot
proteins
sequence_length
181
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12034827}.
uniprot
proteins