Sgce
entrez
20392
canonical
uniprot
O70258
canonical
ensembl
ENSMUSG00000004631
resolver
ensp
ENSMUSP00000004750
resolver
ensp
ENSMUSP00000088185
resolver
ensp
ENSMUSP00000099200
resolver
ensp
ENSMUSP00000111240
resolver
ensp
ENSMUSP00000111242
resolver
ensp
ENSMUSP00000120718
resolver
ensp
ENSMUSP00000121964
resolver
ensp
ENSMUSP00000302218
resolver
ensp
ENSMUSP00000302224
resolver
ensp
ENSMUSP00000302226
resolver
ensp
ENSMUSP00000302234
resolver
ensp
ENSMUSP00000302236
resolver
enst
ENSMUST00000004750
resolver
enst
ENSMUST00000090686
resolver
enst
ENSMUST00000101677
resolver
enst
ENSMUST00000126151
resolver
enst
ENSMUST00000133306
resolver
genesymbol
Sgce
resolver
uniprot
D3Z572
resolver
uniprot
E9PX46
resolver
uniprot
F6R6P2
resolver
uniprot
F6WKE4
resolver
uniprot
F8WGM3
resolver
uniprot
Q4H437
resolver
uniprot
Q4H438
resolver
uniprot
Q6L8N9
resolver
uniprot
Q921G2
resolver
uniprot_entry
D3Z572_MOUSE
resolver
uniprot_entry
E9PX46_MOUSE
resolver
uniprot_entry
F6R6P2_MOUSE
resolver
uniprot_entry
F6WKE4_MOUSE
resolver
uniprot_entry
F8WGM3_MOUSE
resolver
uniprot_entry
Q4H437_MOUSE
resolver
uniprot_entry
Q4H438_MOUSE
resolver
uniprot_entry
Q6L8N9_MOUSE
resolver
uniprot_entry
SGCE_MOUSE
resolver
uniprot_sec
Q921G2
resolver
amino_acid_sequence
MLLFWWWELGDPCAWTGKGRGTLKMSPATTGTFLLTVYTLFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEVSNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEEFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVAFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTHFHIDWCKISLVDKTKQVSTYQEVVRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRDMQTPDIQLVHHSSIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEVIPPTHTDNYDSTNMPLMQAQQNLPHQTQIPQPQTTGKWYP
uniprot
proteins
function
FUNCTION: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
uniprot
proteins
mass_dalton
49736
uniprot
proteins
mutagenesis
MUTAGEN 60; /note="H->P,R: Misfolded, leading to the interaction with TOR1A, ubiquitination and a decrease of the half-life. Impairs intracellular transport. No effect on glycosylation."; /evidence="ECO:0000269|PubMed:17200151"; MUTAGEN 196; /note="L->R: Misfolded, leading to the interaction with TOR1A, ubiquitination and a decrease of the half-life. Impairs intracellular transport. No effect on glycosylation."; /evidence="ECO:0000269|PubMed:17200151
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:17200151}.; PTM: Ubiquitinated, leading to its degradation by the proteasome. {ECO:0000269|PubMed:17200151}.
uniprot
proteins
protein_family
Sarcoglycan alpha/epsilon family
uniprot
proteins
pubmed
10488149
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17200151
uniprot
proteins
pubmed
9405466
uniprot
proteins
sequence_length
437
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane, sarcolemma {ECO:0000269|PubMed:17200151}; Single-pass membrane protein {ECO:0000269|PubMed:17200151}. Golgi apparatus {ECO:0000269|PubMed:17200151}. Cell projection, dendrite {ECO:0000269|PubMed:17200151}. Cytoplasm, cytoskeleton {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 318..338; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins