ATP5MC2
entrez
517
canonical
uniprot
Q06055
canonical
ensembl
ENSG00000135390
resolver
ensp
ENSP00000377878
resolver
ensp
ENSP00000447317
resolver
ensp
ENSP00000448801
resolver
ensp
ENSP00000499883
resolver
ensp
ENSP00000564513
resolver
ensp
ENSP00000564514
resolver
ensp
ENSP00000606970
resolver
ensp
ENSP00000675219
resolver
genesymbol
ATP5MC2
resolver
genesymbol_syn
ATP5G2
resolver
hgnc
HGNC:842
resolver
uniprot
B3KQQ6
resolver
uniprot_entry
AT5G2_HUMAN
resolver
uniprot_sec
B3KQQ6
resolver
amino_acid_sequence
MFACSKFVSTPSLVKSTSQLLSRPLSAVVLKRPEILTDESLSSLAVSCPLTSLVSSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
uniprot
proteins
function
FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
uniprot
proteins
mass_dalton
14637
uniprot
proteins
post_translational_modification
PTM: Trimethylated by ATPSCKMT at Lys-109. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. {ECO:0000269|PubMed:30530489}.
uniprot
proteins
protein_family
ATPase C chain family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
16541075
uniprot
proteins
pubmed
2883974
uniprot
proteins
pubmed
30318146
uniprot
proteins
pubmed
30530489
uniprot
proteins
pubmed
8328972
uniprot
proteins
pubmed
8485160
uniprot
proteins
sequence_length
141
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins