ETV1
entrez
2115
canonical
uniprot
P50549
canonical
ensembl
ENSG00000006468
resolver
ensp
ENSP00000242066
resolver
ensp
ENSP00000384085
resolver
ensp
ENSP00000384138
resolver
ensp
ENSP00000385381
resolver
ensp
ENSP00000385551
resolver
ensp
ENSP00000385686
resolver
ensp
ENSP00000393078
resolver
ensp
ENSP00000394710
resolver
ensp
ENSP00000405327
resolver
ensp
ENSP00000640615
resolver
enst
ENST00000405358
resolver
genesymbol
ETV1
resolver
genesymbol_syn
ER81
resolver
hgnc
HGNC:3490
resolver
uniprot
A4D118
resolver
uniprot
B2R768
resolver
uniprot
B5MCT2
resolver
uniprot
B7Z2C9
resolver
uniprot
B7Z2I4
resolver
uniprot
B7Z618
resolver
uniprot
B7Z9P2
resolver
uniprot
C9JT37
resolver
uniprot
E9PHB1
resolver
uniprot
F5GXR2
resolver
uniprot
O75849
resolver
uniprot
Q4KMQ6
resolver
uniprot
Q59GA7
resolver
uniprot
Q6AI30
resolver
uniprot
Q9UQ71
resolver
uniprot
Q9Y636
resolver
uniprot_entry
B5MCT2_HUMAN
resolver
uniprot_entry
B7Z2C9_HUMAN
resolver
uniprot_entry
ETV1_HUMAN
resolver
uniprot_sec
A4D118
resolver
uniprot_sec
B2R768
resolver
uniprot_sec
B7Z2I4
resolver
uniprot_sec
B7Z618
resolver
uniprot_sec
B7Z9P2
resolver
uniprot_sec
C9JT37
resolver
uniprot_sec
E9PHB1
resolver
uniprot_sec
F5GXR2
resolver
uniprot_sec
O75849
resolver
uniprot_sec
Q4KMQ6
resolver
uniprot_sec
Q59GA7
resolver
uniprot_sec
Q6AI30
resolver
uniprot_sec
Q9UQ71
resolver
uniprot_sec
Q9Y636
resolver
amino_acid_sequence
MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
uniprot
proteins
disease_involvement
DISEASE: Ewing sarcoma (ES) [MIM:612219]: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. {ECO:0000269|PubMed:7700648}. Note=The gene represented in this entry is involved in disease pathogenesis. A chromosomal aberration involving ETV1 is found in patients with Ewing sarcoma. Translocation t(7;22)(p22;q12) with EWSR1. {ECO:0000269|PubMed:7700648}.
uniprot
proteins
function
FUNCTION: Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (PubMed:7651741). Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH) (By similarity). {ECO:0000250|UniProtKB:P41164, ECO:0000269|PubMed:7651741}.
uniprot
proteins
mass_dalton
55131
uniprot
proteins
mutagenesis
MUTAGEN 191; /note="S->A: Loss of phosphorylation by RPS6KA5."; /evidence="ECO:0000269|PubMed:12569367"; MUTAGEN 216; /note="S->A: Loss of phosphorylation by RPS6KA5."; /evidence="ECO:0000269|PubMed:12569367
uniprot
proteins
post_translational_modification
PTM: Sumoylated. {ECO:0000269|PubMed:15561718}.; PTM: Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5; phosphorylation activates transcriptional activity. {ECO:0000269|PubMed:12213813, ECO:0000269|PubMed:12569367}.
uniprot
proteins
protein_family
ETS family
uniprot
proteins
pubmed
12213813
uniprot
proteins
pubmed
12569367
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15561718
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
7651741
uniprot
proteins
pubmed
7700648
uniprot
proteins
sequence_length
477
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}.
uniprot
proteins