GAPT
entrez
202309
canonical
uniprot
Q8N292
canonical
ensembl
ENSG00000175857
resolver
ensp
ENSP00000323075
resolver
ensp
ENSP00000379997
resolver
ensp
ENSP00000422645
resolver
ensp
ENSP00000423113
resolver
ensp
ENSP00000507091
resolver
ensp
ENSP00000508387
resolver
enst
ENST00000318469
resolver
enst
ENST00000396776
resolver
enst
ENST00000502276
resolver
enst
ENST00000511930
resolver
enst
ENST00000513924
resolver
enst
ENST00000515443
resolver
genesymbol
GAPT
resolver
genesymbol_syn
C5orf29
resolver
hgnc
HGNC:26588
resolver
uniprot_entry
GAPT_HUMAN
resolver
amino_acid_sequence
MSKSCGNNLAAISVGISLLLLLVVCGIGCVWHWKHRVATRFTLPRFLQRRSSRRKVCTKTFLGPRIIGLRHEISVETQDHKSAVRGNNTHDNYENVEAGPPKAKGKTDKELYENTGQSNFEEHIYGNETSSDYYNFQKPRPSEVPQDEDIYILPDSY
uniprot
proteins
function
FUNCTION: Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
17883
uniprot
proteins
mutagenesis
MUTAGEN 139; /note="P->A: Abolishes interaction with GRB2."; /evidence="ECO:0000269|PubMed:18559951"; MUTAGEN 141; /note="P->A: Abolishes interaction with GRB2."; /evidence="ECO:0000269|PubMed:18559951"; MUTAGEN 145; /note="P->A: Abolishes interaction with GRB2."; /evidence="ECO:0000269|PubMed:18559951
uniprot
proteins
protein_family
GAPT family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18559951
uniprot
proteins
sequence_length
157
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:18559951}; Single-pass membrane protein {ECO:0000269|PubMed:18559951}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins