FAM98B
entrez
283742
canonical
uniprot
Q52LJ0
canonical
ensembl
ENSG00000171262
resolver
ensp
ENSP00000380734
resolver
genesymbol
FAM98B
resolver
hgnc
HGNC:26773
resolver
uniprot
A8MUW5
resolver
uniprot
Q8N935
resolver
uniprot_entry
FA98B_HUMAN
resolver
uniprot_sec
A8MUW5
resolver
uniprot_sec
Q8N935
resolver
amino_acid_sequence
MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIKSLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFLSTELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKDILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSDRAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY
uniprot
proteins
function
FUNCTION: Accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity and may function toward other RNAs (PubMed:21311021, PubMed:24870230). Could regulate the expression of PRMT1, a protein arginine N-methyltransferase (PubMed:28040436). {ECO:0000269|PubMed:21311021, ECO:0000269|PubMed:24870230, ECO:0000269|PubMed:28040436}.
uniprot
proteins
mass_dalton
45547
uniprot
proteins
protein_family
FAM98 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
18445686
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21311021
uniprot
proteins
pubmed
24608264
uniprot
proteins
pubmed
24870230
uniprot
proteins
pubmed
28040436
uniprot
proteins
sequence_length
433
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24608264}. Cytoplasm {ECO:0000269|PubMed:18445686, ECO:0000269|PubMed:24608264}.
uniprot
proteins