GALR2
entrez
8811
canonical
uniprot
O43603
canonical
ensembl
ENSG00000182687
resolver
ensp
ENSP00000329684
resolver
enst
ENST00000329003
resolver
genesymbol
GALR2
resolver
genesymbol_syn
GALNR2
resolver
hgnc
HGNC:4133
resolver
uniprot
A5JUU4
resolver
uniprot
Q32MN8
resolver
uniprot_entry
GALR2_HUMAN
resolver
uniprot_sec
A5JUU4
resolver
uniprot_sec
Q32MN8
resolver
amino_acid_sequence
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
uniprot
proteins
function
FUNCTION: Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)). {ECO:0000269|PubMed:24517231, ECO:0000269|PubMed:25691535, ECO:0000269|PubMed:9480833, ECO:0000269|PubMed:9685625, ECO:0000269|PubMed:9832121, ECO:0000269|PubMed:9880084}.
uniprot
proteins
mass_dalton
41700
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24517231
uniprot
proteins
pubmed
25691535
uniprot
proteins
pubmed
9480833
uniprot
proteins
pubmed
9685625
uniprot
proteins
pubmed
9832121
uniprot
proteins
pubmed
9880084
uniprot
proteins
sequence_length
387
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 29..49; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 61..81; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 100..121; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 142..162; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 188..208; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 238..258; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 261..281; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins