KCNG2
entrez
26251
canonical
uniprot
Q9UJ96
canonical
ensembl
ENSG00000178342
resolver
ensp
ENSP00000315654
resolver
ensp
ENSP00000628352
resolver
ensp
ENSP00000628353
resolver
enst
ENST00000316249
resolver
enst
ENST00000958293
resolver
enst
ENST00000958294
resolver
genesymbol
KCNG2
resolver
genesymbol_syn
KCNF2
resolver
hgnc
HGNC:6249
resolver
uniprot_entry
KCNG2_HUMAN
resolver
amino_acid_sequence
MEPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
uniprot
proteins
function
FUNCTION: Regulatory alpha-subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1, can modulate the kinetics and conductance-voltage relationship (PubMed:10551266). Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values (Probable). Potassium channel subunit that does not form functional channels by itself (Probable). {ECO:0000269|PubMed:10551266, ECO:0000305|PubMed:10551266}.
uniprot
proteins
mass_dalton
51240
uniprot
proteins
protein_family
G (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv6.2/KCNG2 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
10551266
uniprot
proteins
sequence_length
466
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q14721}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P63142}.
uniprot
proteins
transmembrane_region
TRANSMEM 175..196; /note="Helical; Name=Segment S1"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 218..239; /note="Helical; Name=Segment S2"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 251..271; /note="Helical; Name=Segment S3"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 284..304; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 320..341; /note="Helical; Name=Segment S5"; /evidence="ECO:0000250|UniProtKB:P63142"; TRANSMEM 384..412; /note="Helical; Name=Segment S6"; /evidence="ECO:0000250|UniProtKB:P63142
uniprot
proteins