Trim2
entrez
361970
canonical
uniprot
D3ZQG6
canonical
ensembl
ENSRNOG00000010124
resolver
ensp
ENSRNOP00000060362
resolver
ensp
ENSRNOP00000072306
resolver
ensp
ENSRNOP00000082573
resolver
enst
ENSRNOT00000067618
resolver
enst
ENSRNOT00000085382
resolver
enst
ENSRNOT00000107931
resolver
genesymbol
Trim2
resolver
uniprot
A0A0G2K2M8
resolver
uniprot
A0A8I5ZV62
resolver
uniprot
D3ZM62
resolver
uniprot_entry
A0A0G2K2M8_RAT
resolver
uniprot_entry
A0A8I5ZV62_RAT
resolver
uniprot_entry
D3ZM62_RAT
resolver
uniprot_entry
TRIM2_RAT
resolver
amino_acid_sequence
MASEGASIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNGEDPSILQTVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTSGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSNDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSSNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
function
FUNCTION: UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity. {ECO:0000250|UniProtKB:Q9C040, ECO:0000250|UniProtKB:Q9ESN6, ECO:0000269|PubMed:21478148}.
uniprot
proteins
mass_dalton
81427
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
post_translational_modification
PTM: RING-type zinc finger-dependent and UBE2D1-dependent autoubiquitination. {ECO:0000250|UniProtKB:Q9ESN6}.
uniprot
proteins
protein_family
TRIM/RBCC family
uniprot
proteins
pubmed
21478148
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
744
uniprot
proteins