FGF21
entrez
26291
canonical
uniprot
Q9NSA1
canonical
ensembl
ENSG00000105550
resolver
ensp
ENSP00000222157
resolver
ensp
ENSP00000471477
resolver
enst
ENST00000222157
resolver
enst
ENST00000593756
resolver
genesymbol
FGF21
resolver
hgnc
HGNC:3678
resolver
uniprot
Q8N683
resolver
uniprot_entry
FGF21_HUMAN
resolver
uniprot_sec
Q8N683
resolver
amino_acid_sequence
MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS
uniprot
proteins
function
FUNCTION: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. {ECO:0000250|UniProtKB:Q9JJN1, ECO:0000269|PubMed:15902306, ECO:0000269|PubMed:17623664}.
uniprot
proteins
mass_dalton
22300
uniprot
proteins
protein_family
Heparin-binding growth factors family
uniprot
proteins
pubmed
10858549
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15902306
uniprot
proteins
pubmed
17623664
uniprot
proteins
pubmed
18829467
uniprot
proteins
pubmed
19117008
uniprot
proteins
pubmed
20094046
uniprot
proteins
sequence_length
209
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q9JJN1}.
uniprot
proteins