Prss57
entrez
73106
canonical
uniprot
Q14B24
canonical
ensembl
ENSMUSG00000020323
resolver
ensp
ENSMUSP00000020573
resolver
ensp
ENSMUSP00000132215
resolver
enst
ENSMUST00000020573
resolver
enst
ENSMUST00000169684
resolver
genesymbol
Prss57
resolver
genesymbol_syn
Prssl1
resolver
uniprot_entry
PRS57_MOUSE
resolver
amino_acid_sequence
MPSSTAMVPGTRGGWHCLVLTTAAALTQLMWLPGCCGSYIVGGHEVTPHSRPYMASVSFEGHHYCGGFLIHTHWVVSAAHCFSDRDPSMGLVVLGAHALLAPEPTQQTFSIAAAVSHPDFQPATQANDICLLRLNGSAVLGPAVRLLRLPRRNAKPPAAGTRCHVSGWGFVSDFEEPPPGLMEVEVRILDLSVCNSSWQGQLNPAMLCTHSGDRRRRGFCSADSGGPLVCGRRAHGLVSFSGLWCGDPKTPDVYTQVSAFVTWIWDVVRASSSPGSTGRSVRAV
uniprot
proteins
ec_number
3.4.21.-
uniprot
proteins
function
FUNCTION: Serine protease that cleaves preferentially after Arg residues. Can also cleave after citrulline (deimidated arginine) and methylarginine residues. {ECO:0000250|UniProtKB:Q6UWY2}.
uniprot
proteins
mass_dalton
30341
uniprot
proteins
post_translational_modification
PTM: After cleavage of the signal peptide, the N-terminus is probably further processed by CTSC. Processing by CTSC is probably required for accumulation in cytoplasmic granules; in the absence of CTSC the protein does not accumulate. {ECO:0000250|UniProtKB:Q6UWY2}.; PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q6UWY2}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
284
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic granule lumen {ECO:0000250|UniProtKB:Q6UWY2}. Secreted {ECO:0000250|UniProtKB:Q6UWY2}. Note=Stored in cytoplasmic granules and secreted as active enzyme in response to stimulation of neutrophils. {ECO:0000250|UniProtKB:Q6UWY2}.
uniprot
proteins