Ereg
entrez
13874
canonical
uniprot
Q61521
canonical
ensembl
ENSMUSG00000029377
resolver
ensp
ENSMUSP00000031324
resolver
enst
ENSMUST00000031324
resolver
genesymbol
Ereg
resolver
uniprot
Q7M0A8
resolver
uniprot_entry
EREG_MOUSE
resolver
uniprot_sec
Q7M0A8
resolver
amino_acid_sequence
METLPASWVLTLLCLGSHLLQAVISTTVIPSCIPGESEDNCTALVQMEDDPRVAQVQITKCSSDMDGYCLHGQCIYLVDMREKFCRCEVGYTGLRCEHFFLTVHQPLSKEYVALTVILIFLFLIITAGCIYYFCRWYKNRKSKKSREEYERVTSGDPVLPQV
uniprot
proteins
function
FUNCTION: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (By similarity). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). {ECO:0000250|UniProtKB:O14944, ECO:0000303|PubMed:24631357}.
uniprot
proteins
mass_dalton
18474
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
24631357
uniprot
proteins
pubmed
7706296
uniprot
proteins
pubmed
8549764
uniprot
proteins
sequence_length
162
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Epiregulin]: Secreted, extracellular space {ECO:0000250|UniProtKB:O14944}.; SUBCELLULAR LOCATION: [Proepiregulin]: Cell membrane {ECO:0000250|UniProtKB:O14944}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:O14944}.
uniprot
proteins
transmembrane_region
TRANSMEM 113..133; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins