Parp11
entrez
101187
canonical
uniprot
Q8CFF0
canonical
ensembl
ENSMUSG00000037997
resolver
ensp
ENSMUSP00000036127
resolver
ensp
ENSMUSP00000107810
resolver
ensp
ENSMUSP00000107812
resolver
ensp
ENSMUSP00000242202
resolver
ensp
ENSMUSP00000242204
resolver
ensp
ENSMUSP00000242206
resolver
ensp
ENSMUSP00000242215
resolver
genesymbol
Parp11
resolver
uniprot
Q3UAF2
resolver
uniprot
Q3UZR7
resolver
uniprot
Q8BML7
resolver
uniprot_entry
PAR11_MOUSE
resolver
uniprot_entry
Q8BML7_MOUSE
resolver
uniprot_sec
Q3UAF2
resolver
uniprot_sec
Q3UZR7
resolver
amino_acid_sequence
MFHKTEEFFPKKTDSDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH
uniprot
proteins
ec_number
2.4.2.-
uniprot
proteins
function
FUNCTION: Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins (By similarity). Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (PubMed:25673562). Inhibits the type I interferon activated signaling pathway (By similarity). Mechanistically, mono-ADP-ribosylates beta-TrCP/BTRC to promote IFNAR1 ubiquitination and protect BTRC from ubiquitin-proteasome degradation (By similarity). {ECO:0000250|UniProtKB:Q9NR21, ECO:0000269|PubMed:25673562}.
uniprot
proteins
mass_dalton
38737
uniprot
proteins
post_translational_modification
PTM: Auto-mono-ADP-ribosylated. {ECO:0000250|UniProtKB:Q9NR21}.
uniprot
proteins
protein_family
ARTD/PARP family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
25673562
uniprot
proteins
sequence_length
331
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q9NR21}. Note=Colocalizes with NUP153 at nuclear pores. {ECO:0000250|UniProtKB:Q9NR21}.
uniprot
proteins