Il18rap
entrez
16174
canonical
uniprot
Q9Z2B1
canonical
ensembl
ENSMUSG00000026068
resolver
ensp
ENSMUSP00000027237
resolver
enst
ENSMUST00000027237
resolver
genesymbol
Il18rap
resolver
uniprot
Q0VBK3
resolver
uniprot
Q3TTU1
resolver
uniprot_entry
I18RA_MOUSE
resolver
uniprot_entry
Q0VBK3_MOUSE
resolver
uniprot_entry
Q3TTU1_MOUSE
resolver
amino_acid_sequence
MLCLGWVFLWFVAGEKTTGFNHSACATKKLLWTYSARGAENFVLFCDLQELQEQKFSHASQLSPTQSPAHKPCSGSQKDLSDVQWYMQPRSGSPLEEISRNSPHMQSEGMLHILAPQTNSIWSYICRPRIRSPQDMACCIKTVLEVKPQRNVSCGNTAQDEQVLLLGSTGSIHCPSLSCQSDVQSPEMTWYKDGRLLPEHKKNPIEMADIYVFNQGLYVCDYTQSDNVSSWTVRAVVKVRTIGKDINVKPEILDPITDTLDVELGKPLTLPCRVQFGFQRLSKPVIKWYVKESTQEWEMSVFEEKRIQSTFKNEVIERTIFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEEVVFVYILLGTALMLVGVLVAAAFLYWYWIEVVLLCRTYKNKDETLGDKKEFDAFVSYSNWSSPETDAVGSLSEEHLALNLFPEVLEDTYGYRLCLLDRDVTPGGVYADDIVSIIKKSRRGIFILSPSYLNGPRVFELQAAVNLALVDQTLKLILIKFCSFQEPESLPYLVKKALRVLPTVTWKGLKSVHASSRFWTQIRYHMPVKNSNRFMFNGLRIFLKGFSPEKDLVTQKPLEGMPKSGNDHGAQNLLLYSDQKRC
uniprot
proteins
ec_number
3.2.2.6
uniprot
proteins
function
FUNCTION: Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:11046021, PubMed:15843532, PubMed:9792649). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (By similarity). {ECO:0000250|UniProtKB:O95256, ECO:0000269|PubMed:11046021, ECO:0000269|PubMed:15843532, ECO:0000269|PubMed:9792649}.
uniprot
proteins
mass_dalton
70094
uniprot
proteins
protein_family
Interleukin-1 receptor family
uniprot
proteins
pubmed
11046021
uniprot
proteins
pubmed
15843532
uniprot
proteins
pubmed
9792649
uniprot
proteins
sequence_length
614
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:O95256}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 357..377; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins