Degs2
entrez
70059
canonical
uniprot
Q8R2F2
canonical
ensembl
ENSMUSG00000021263
resolver
ensp
ENSMUSP00000021691
resolver
ensp
ENSMUSP00000125891
resolver
genesymbol
Degs2
resolver
uniprot
Q3TR85
resolver
uniprot
Q78JJ1
resolver
uniprot_entry
DEGS2_MOUSE
resolver
uniprot_sec
Q3TR85
resolver
uniprot_sec
Q78JJ1
resolver
amino_acid_sequence
MGNSAARSDFEWVYSDQPHTQRRKEMLAKYPAIKALMRPDPHIKWTVSGMVLVQVLACWLVRGLSWRWLLFWAYAFGGCINHSLTLAIHDISHNTAFGTSCVSRNRWFAIFANLPIGLPYATSFKKYHVDHHRYLGGDGLDVDIPTNFEGWFFCTPARKLLWLVLQPFFYSLRPLCVNPKVVTRMEILNALVQLAFDVTIFALWGIKPIVYLLGSSLLGLGLHPISGHFVAEHYMFLKGHETYSYYGPLNWITFNVGYHMEHHDFPSIPGYYLPLVRKIAPEYYDHLPQHHSWVKVLWDFVFEDSMGPYSRVKRKCKLAKDHL
uniprot
proteins
ec_number
1.14.18.5
uniprot
proteins
ec_number
1.14.19.17
uniprot
proteins
function
FUNCTION: Bifunctional enzyme which acts both as a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase. {ECO:0000269|PubMed:11937514, ECO:0000269|PubMed:14731113, ECO:0000269|PubMed:16571104}.
uniprot
proteins
mass_dalton
37491
uniprot
proteins
pathway_participation
PATHWAY: Membrane lipid metabolism; sphingolipid biosynthesis. {ECO:0000269|PubMed:11937514}.
uniprot
proteins
protein_family
DEGS subfamily
uniprot
proteins
protein_family
Fatty acid desaturase type 1 family
uniprot
proteins
pubmed
11937514
uniprot
proteins
pubmed
14731113
uniprot
proteins
pubmed
15474011
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16571104
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16571104, ECO:0000305}; Multi-pass membrane protein {ECO:0000269|PubMed:16571104, ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 41..61; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 68..88; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 210..231; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins