Pcsk2
entrez
25121
canonical
uniprot
P28841
canonical
ensembl
ENSRNOG00000005438
resolver
ensembl
ENSRNOG00055023581
resolver
ensembl
ENSRNOG00060001418
resolver
ensembl
ENSRNOG00065027777
resolver
ensp
ENSRNOP00000007249
resolver
ensp
ENSRNOP00055032926
resolver
ensp
ENSRNOP00060001279
resolver
ensp
ENSRNOP00065039282
resolver
enst
ENSRNOT00000007249
resolver
enst
ENSRNOT00055040528
resolver
enst
ENSRNOT00060002083
resolver
enst
ENSRNOT00065047874
resolver
genesymbol
Pcsk2
resolver
genesymbol_syn
Nec-2
resolver
genesymbol_syn
Nec2
resolver
genesymbol_syn
Rpc2
resolver
uniprot_entry
NEC2_RAT
resolver
amino_acid_sequence
MEGGCGSQWKAAGLLFCVMVFASAERPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNSDASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANVDLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKLVLTLQTNACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGLLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKQELEEELDEAVERSLQSILRKN
uniprot
proteins
ec_number
3.4.21.94
uniprot
proteins
function
FUNCTION: Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells. Mediates the release of insulin from proinsulin. {ECO:0000250|UniProtKB:P16519}.
uniprot
proteins
mass_dalton
70753
uniprot
proteins
protein_family
Furin subfamily
uniprot
proteins
protein_family
Peptidase S8 family
uniprot
proteins
pubmed
1791845
uniprot
proteins
pubmed
1954888
uniprot
proteins
pubmed
24090084
uniprot
proteins
sequence_length
637
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P16519}. Secreted {ECO:0000250|UniProtKB:P16519}. Note=Localized in the secretion granules. {ECO:0000250|UniProtKB:P16519}.
uniprot
proteins