Mstn
entrez
29152
canonical
uniprot
O35312
canonical
ensembl
ENSRNOG00000021294
resolver
ensembl
ENSRNOG00055004850
resolver
ensembl
ENSRNOG00060016957
resolver
ensembl
ENSRNOG00065029971
resolver
ensp
ENSRNOP00000038159
resolver
ensp
ENSRNOP00055005820
resolver
ensp
ENSRNOP00060023342
resolver
ensp
ENSRNOP00065042617
resolver
enst
ENSRNOT00000038093
resolver
enst
ENSRNOT00055007724
resolver
enst
ENSRNOT00060028990
resolver
enst
ENSRNOT00065051777
resolver
genesymbol
Mstn
resolver
genesymbol_syn
Gdf8
resolver
uniprot_entry
GDF8_RAT
resolver
amino_acid_sequence
MIQKPQMYVYIYLFVLIAAGPVDLNEDSEREANVEKEGLCNACAWRQNTRYSRIEAIKIQILSKLRLETAPNISKDAIRQLLPRAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQADGKPKCCFFKFSSKIQYNKVVKAQLWIYLRAVKTPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMSPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
uniprot
proteins
function
FUNCTION: Acts specifically as a negative regulator of skeletal muscle growth. {ECO:0000250|UniProtKB:O08689}.
uniprot
proteins
mass_dalton
42829
uniprot
proteins
post_translational_modification
PTM: Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase. {ECO:0000250|UniProtKB:O08689}.
uniprot
proteins
protein_family
TGF-beta family
uniprot
proteins
pubmed
9356471
uniprot
proteins
sequence_length
376
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:O08689}.
uniprot
proteins