Cryab
entrez
25420
canonical
uniprot
P23928
canonical
ensembl
ENSRNOG00000010524
resolver
ensembl
ENSRNOG00055029072
resolver
ensembl
ENSRNOG00060014408
resolver
ensembl
ENSRNOG00065017518
resolver
ensp
ENSRNOP00000055901
resolver
ensp
ENSRNOP00055041420
resolver
ensp
ENSRNOP00060019620
resolver
ensp
ENSRNOP00065023231
resolver
enst
ENSRNOT00000059127
resolver
enst
ENSRNOT00055050334
resolver
enst
ENSRNOT00060024605
resolver
enst
ENSRNOT00065029284
resolver
genesymbol
Cryab
resolver
uniprot
Q6LDR2
resolver
uniprot_entry
CRYAB_RAT
resolver
uniprot_sec
Q6LDR2
resolver
amino_acid_sequence
MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSEMRMEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQASGPERTIPITREEKPAVTAAPKK
uniprot
proteins
function
FUNCTION: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity). {ECO:0000250|UniProtKB:P23927}.
uniprot
proteins
mass_dalton
20089
uniprot
proteins
protein_family
Small heat shock protein (HSP20) family
uniprot
proteins
pubmed
10751411
uniprot
proteins
pubmed
16641100
uniprot
proteins
pubmed
1764082
uniprot
proteins
pubmed
1765091
uniprot
proteins
pubmed
1783614
uniprot
proteins
pubmed
2176207
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2912453
uniprot
proteins
pubmed
8282729
uniprot
proteins
pubmed
8639509
uniprot
proteins
sequence_length
175
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P02511}. Nucleus {ECO:0000250|UniProtKB:P02511}. Secreted {ECO:0000250|UniProtKB:P02511}. Lysosome {ECO:0000250|UniProtKB:P23927}. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. Localizes at the Z-bands and the intercalated disk in cardiomyocytes. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. {ECO:0000250|UniProtKB:P02511}.
uniprot
proteins