Hsd3b2
entrez
15493
canonical
uniprot
P26149
canonical
ensembl
ENSMUSG00000063730
resolver
ensp
ENSMUSP00000102635
resolver
ensp
ENSMUSP00000102636
resolver
ensp
ENSMUSP00000136533
resolver
enst
ENSMUST00000107021
resolver
enst
ENSMUST00000107022
resolver
enst
ENSMUST00000177651
resolver
genesymbol
Hsd3b2
resolver
uniprot
B1ARN7
resolver
uniprot
Q8R0J6
resolver
uniprot_entry
3BHS2_MOUSE
resolver
uniprot_sec
B1ARN7
resolver
uniprot_sec
Q8R0J6
resolver
amino_acid_sequence
MPGWSCLVTGAGGFLGQRIIQLLVQEEDLEEIRVLDKVFRPETRKEFFNLETSIKVTVLEGDILDTQYLRRACQGISVVIHTAAIIDVTGVIPRQTILDVNLKGTQNLLEACIQASVPAFIFSSSVDVAGPNSYKEIVLNGHEEECHESTWSDPYPYSKKMAEKAVLAANGSMLKNGGTLQTCALRPMCIYGERSPLISNIIIMALKHKGILRSFGKFNTANPVYVGNVAWAHILAARGLRDPKKSPNIQGEFYYISDDTPHQSFDDISYTLSKEWGFCLDSSWSLPVPLLYWLAFLLETVSFLLSPIYRYIPPFNRHLVTLSGSTFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
uniprot
proteins
ec_number
1.1.1.145
uniprot
proteins
ec_number
5.3.3.1
uniprot
proteins
function
FUNCTION: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. {ECO:0000250|UniProtKB:P26439}.
uniprot
proteins
mass_dalton
41923
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; steroid biosynthesis. {ECO:0000250|UniProtKB:P26439}.
uniprot
proteins
protein_family
3-beta-HSD family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1924345
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P26439}; Single-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:P26439}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins