Hnf1a
entrez
24817
canonical
uniprot
P15257
canonical
ensembl
ENSRNOG00000001183
resolver
ensembl
ENSRNOG00055002002
resolver
ensembl
ENSRNOG00060007240
resolver
ensembl
ENSRNOG00065006331
resolver
ensp
ENSRNOP00000001565
resolver
ensp
ENSRNOP00055002403
resolver
ensp
ENSRNOP00060008942
resolver
ensp
ENSRNOP00065007019
resolver
enst
ENSRNOT00000001565
resolver
enst
ENSRNOT00055003204
resolver
enst
ENSRNOT00060011889
resolver
enst
ENSRNOT00065009712
resolver
genesymbol
Hnf1a
resolver
genesymbol_syn
Hnf-1
resolver
genesymbol_syn
Hnf-1a
resolver
genesymbol_syn
Tcf1
resolver
uniprot_entry
HNF1A_RAT
resolver
amino_acid_sequence
MVSKLSQLQTELLAALLESGLSKEALIQALGEPGPYLMVGDGPLDKGESCGGTRGDLTELPNGLGETRGSEDDTDDDGEDFAPPILKELENLSPEEAAHQKAVVESLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHAGQGGLIEEPTGDELPTKKGRRNRFKWGPASQQILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEAFRHKLAMDTYNGPPPGPGPGPALPAHSSPGLPTTTLSPSKVHGVRYGQSATSEAAEVPSSSGGPLVTVSAALHQVSPTGLEPSSLLSTEAKLVSATGGPLPPVSTLTALHSLEQTSPGLNQQPQNLIMASLPGVMTIGPGEPASLGPTFTNTGASTLVIGLASTQAQSVPVINSMGSSLTTLQPVQFSQPLHPSYQQPLMPPVQSHVAQSPFMATMAQLQSPHALYSHKPEVAQYTHTSLLPQTMLITDTNLSTLASLTPTKQVFTSDTEASSEPGLHEPSSPATTIHIPSQDPSNIQHLQPAHRLSTSPTVSSSSLVLYQSSDSNGHSHLLPSNHGVIETFISTQMASSSQ
uniprot
proteins
function
FUNCTION: Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity). {ECO:0000250|UniProtKB:P22361}.
uniprot
proteins
mass_dalton
67213
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated in s SPOP-dependent manner; leading to prteasomal degradation. {ECO:0000250|UniProtKB:P20823}.
uniprot
proteins
protein_family
HNF1 homeobox family
uniprot
proteins
pubmed
1354855
uniprot
proteins
pubmed
1967225
uniprot
proteins
pubmed
1970973
uniprot
proteins
pubmed
1988016
uniprot
proteins
pubmed
2216777
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
2571419
uniprot
proteins
pubmed
7937157
uniprot
proteins
pubmed
8491172
uniprot
proteins
pubmed
8491173
uniprot
proteins
pubmed
9126845
uniprot
proteins
sequence_length
628
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins