Lrrc52
entrez
240899
canonical
uniprot
Q5M8M9
canonical
ensembl
ENSMUSG00000040485
resolver
ensp
ENSMUSP00000047213
resolver
enst
ENSMUST00000036643
resolver
genesymbol
Lrrc52
resolver
uniprot_entry
LRC52_MOUSE
resolver
amino_acid_sequence
MSLASGPSSKLLLFSLGMGLVSGSKCPNKCVCQDQEVACIDLHLTEYPADIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFRLIYLDLSSNNLTSISPFSFSVLTNLVRLNISHNPHLLYLDKYVFANTTSLRYLDLRNTGLHIIDHNGFHHLVVLQTLYLSGNPWICNCSFLDFTIHLLVSHMDHPDAQNATCTEPAELKGWPITKVGNPLQYMCITHLDQQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRTSSGDDTEDETGSRFANQIFRSNTHLGPIRRFPELI
uniprot
proteins
function
FUNCTION: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium (By similarity). KCNU1 channel auxiliary protein. Modulates KCNU1 gating properties, shifting KCNU1 gating to more negative potentials at a given pH (PubMed:22084117, PubMed:25675513). {ECO:0000250, ECO:0000269|PubMed:22084117, ECO:0000269|PubMed:25675513}.
uniprot
proteins
mass_dalton
35295
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:22084117}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22084117
uniprot
proteins
pubmed
25675513
uniprot
proteins
sequence_length
314
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:22084117}; Single-pass membrane protein {ECO:0000269|PubMed:22084117}. Note=Expression at the cell surface may require the presence of KCNU1.
uniprot
proteins
transmembrane_region
TRANSMEM 245..265; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins