Abhd4
entrez
105501
canonical
uniprot
Q8VD66
canonical
ensembl
ENSMUSG00000040997
resolver
ensp
ENSMUSP00000044134
resolver
ensp
ENSMUSP00000137214
resolver
ensp
ENSMUSP00000159351
resolver
enst
ENSMUST00000041197
resolver
enst
ENSMUST00000180359
resolver
enst
ENSMUST00000239403
resolver
genesymbol
Abhd4
resolver
uniprot
A0A6I8MX04
resolver
uniprot
J3QK35
resolver
uniprot
Q3U7M5
resolver
uniprot
Q8C0M2
resolver
uniprot_entry
A0A6I8MX04_MOUSE
resolver
uniprot_entry
ABHD4_MOUSE
resolver
uniprot_entry
J3QK35_MOUSE
resolver
uniprot_entry
Q3U7M5_MOUSE
resolver
uniprot_entry
Q8C0M2_MOUSE
resolver
amino_acid_sequence
MADDLEQQPQGWLSSWLPTWRPTSMSQLKNVEARILQCLQNKFLARYVSLPNQNKIWTVTVSPEQKDRTPLVMVHGFGGGVGLWILNMDSLSARRTLHTFDLLGFGRSSRPTFPRDPEGAEDEFVASIETWRETMGIPTMILLGHSLGGFLATSYSIKYPERVKHLILVDPWGFPLRPTDPSEIRAPPTWVKAVASVLGRSNPLAVLRVAGPWGPGLVQRFRPDFKRKFADFFEDDTISEYIYHCNAQNPSGETAFKAMMESFGWARRPMLERIHLIRKDVPITMIYGANTWIDTSTGKKVKMQRPDSYVRDMEIEGASHHVYADQPHIFNAVVEEICNSVD
uniprot
proteins
ec_number
3.1.1.-
uniprot
proteins
function
FUNCTION: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis (PubMed:16818490, PubMed:25853435). Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains (PubMed:16818490, PubMed:25853435). Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine (PubMed:16818490). {ECO:0000269|PubMed:16818490, ECO:0000269|PubMed:25853435}.
uniprot
proteins
mass_dalton
38861
uniprot
proteins
protein_family
ABHD4/ABHD5 subfamily
uniprot
proteins
protein_family
Peptidase S33 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16818490
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25853435
uniprot
proteins
sequence_length
342
uniprot
proteins