Fgd4
entrez
246174
canonical
uniprot
O88387
canonical
ensembl
ENSRNOG00000059491
resolver
ensembl
ENSRNOG00055003163
resolver
ensembl
ENSRNOG00060002642
resolver
ensembl
ENSRNOG00065008509
resolver
ensp
ENSRNOP00000072359
resolver
ensp
ENSRNOP00000092594
resolver
ensp
ENSRNOP00000100627
resolver
ensp
ENSRNOP00055003653
resolver
ensp
ENSRNOP00060002972
resolver
ensp
ENSRNOP00065010011
resolver
enst
ENSRNOT00000078367
resolver
enst
ENSRNOT00000100508
resolver
enst
ENSRNOT00000145334
resolver
enst
ENSRNOT00055004930
resolver
enst
ENSRNOT00060004232
resolver
enst
ENSRNOT00065013507
resolver
genesymbol
Fgd4
resolver
uniprot
A0A0G2K2S8
resolver
uniprot
A0A8I6GK89
resolver
uniprot_entry
A0A0G2K2S8_RAT
resolver
uniprot_entry
A0A8I6GK89_RAT
resolver
uniprot_entry
FGD4_RAT
resolver
amino_acid_sequence
MEESNPAPTSCASKGKHSKVSDLISHFEGGSVLSSYTDVQKDSTMNLNIPQTPRQHGLTSTTPQKLPSHKSPQKQEKDSDQNQGQHGCLANGVAAAQSQMECETEKEAALSPETDTQTAAASPDAHVLNGVRNETTTDSASSVTNSHDENACDSSCRTQGTDLGLPSKEGEPVIEAELQERENGLSTEGLNPLDQHHEVKETNEQKLHKIATELLLTERAYVSRLNLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDAPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIMSGFAESEEKKRRGILEIESAEVSGNSEVCSFLQYMEKSKPWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYIVDDMPKSADLPHSFKLTQSKSVHSFAADSEELKQKWLKIILLAVTGETPDGPSEHLDTLDNLPGPKEKSEC
uniprot
proteins
function
FUNCTION: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8. {ECO:0000269|PubMed:10464238, ECO:0000269|PubMed:9668039}.
uniprot
proteins
mass_dalton
86454
uniprot
proteins
pubmed
10464238
uniprot
proteins
pubmed
9668039
uniprot
proteins
sequence_length
766
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10464238}. Cell projection, filopodium {ECO:0000269|PubMed:10464238}. Note=Concentrated in filopodia and poorly detected at lamellipodia. Binds along the sides of actin fibers.
uniprot
proteins