Sycn
entrez
68416
canonical
uniprot
Q8VCK7
canonical
ensembl
ENSMUSG00000084174
resolver
ensp
ENSMUSP00000112770
resolver
enst
ENSMUST00000119180
resolver
genesymbol
Sycn
resolver
uniprot_entry
SYCN_MOUSE
resolver
amino_acid_sequence
MSLLCPLLLALALVAVPGAHGNCPVPADLKKSDGTRTCARLYEKSDPYYDNCCQGPVLSVEPGTDLPYLPSGWSNTASSLVVGQRCEITVWSLPGKHGKTRKFTAGSYPRLEEYRKGIFGDWSDSISALYCKCY
uniprot
proteins
function
FUNCTION: Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues. {ECO:0000269|PubMed:11839820, ECO:0000269|PubMed:15040787, ECO:0000269|PubMed:15462671}.
uniprot
proteins
mass_dalton
14595
uniprot
proteins
post_translational_modification
PTM: Contains intrachain disulfide bonds. {ECO:0000250}.
uniprot
proteins
pubmed
11839820
uniprot
proteins
pubmed
15040787
uniprot
proteins
pubmed
15462671
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
134
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Zymogen granule membrane {ECO:0000250|UniProtKB:O35775}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35775}; Lumenal side {ECO:0000250|UniProtKB:O35775}. Zymogen granule lumen {ECO:0000250|UniProtKB:O35775}. Note=Associated in a cholesterol-dependent manner with lipid rafts of zymogen granule membranes. {ECO:0000250|UniProtKB:O35775}.
uniprot
proteins