Gphb5
entrez
217674
canonical
uniprot
Q812B2
canonical
ensembl
ENSMUSG00000048982
resolver
ensp
ENSMUSP00000061488
resolver
enst
ENSMUST00000051079
resolver
genesymbol
Gphb5
resolver
genesymbol_syn
Gpb5
resolver
genesymbol_syn
Zlut1
resolver
uniprot
B2RTN6
resolver
uniprot
Q8BJV2
resolver
uniprot_entry
B2RTN6_MOUSE
resolver
uniprot_entry
GPHB5_MOUSE
resolver
uniprot_sec
Q8BJV2
resolver
amino_acid_sequence
MKLVYLVLGAVALLLLGGPDSVLSSSSGNLHTFVGCAVREFTFMAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAYHRVCTYNETRQVTVKLPNCAPGVDPFYTYPMAVRCDCGACSTATTECETI
uniprot
proteins
function
FUNCTION: Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. {ECO:0000250|UniProtKB:Q86YW7}.
uniprot
proteins
mass_dalton
14249
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q86YW7}.
uniprot
proteins
protein_family
Glycoprotein hormones subunit beta family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16210345
uniprot
proteins
sequence_length
130
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
uniprot
proteins