Myb
entrez
17863
canonical
uniprot
P06876
canonical
ensembl
ENSMUSG00000019982
resolver
ensp
ENSMUSP00000020158
resolver
ensp
ENSMUSP00000139699
resolver
enst
ENSMUST00000020158
resolver
enst
ENSMUST00000188495
resolver
genesymbol
Myb
resolver
uniprot
A0A087WPA7
resolver
uniprot
E9QMG8
resolver
uniprot
Q3UUX5
resolver
uniprot
Q61929
resolver
uniprot_entry
A0A087WPA7_MOUSE
resolver
uniprot_entry
MYB_MOUSE
resolver
uniprot_entry
Q3UUX5_MOUSE
resolver
uniprot_sec
E9QMG8
resolver
uniprot_sec
Q61929
resolver
amino_acid_sequence
MARRPRHSIYSSDEDDEDIEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPSKASQTPVATSFQKNNHLMGFGHASPPSQLSPSGQSSVNSEYPYYHIAEAQNISSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTCSYPGWHSTSIVDQTRPHGDSAPVSCLGEHHATPSLPADPGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSFLNTSSNHESSGLDAPTLPSTPLIGHKLTPCRDQTVKTQKENSIFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHAVEDLQDVIKQESDESGIVAEFQESGPPLLKKIKQEVESPTEKSGNFFCSNHWAENSLSTQLFSQASPVADAPNILTSSVLMTPVSEDEDNVLKAFTVPKNRPLVGPLQPCSGAWEPASCGKTEDQMTASGPARKYVNAFSARTLVM
uniprot
proteins
function
FUNCTION: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. {ECO:0000269|PubMed:16162816}.
uniprot
proteins
mass_dalton
71422
uniprot
proteins
mutagenesis
MUTAGEN 499; /note="K->R: Complete loss of TRAF7-mediated SUMOylatiom; when associated with R-523."; /evidence="ECO:0000269|PubMed:16162816"; MUTAGEN 523; /note="K->R: Complete loss of TRAF7-mediated SUMOylatiom; when associated with R-499."; /evidence="ECO:0000269|PubMed:16162816
uniprot
proteins
post_translational_modification
PTM: SUMOylated by TRAF7; leading to MYB transcriptional activity inhibition. {ECO:0000269|PubMed:16162816}.; PTM: Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. {ECO:0000250}.; PTM: Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.; PTM: Phosphorylated by HIPK1. This phosphorylation reduces MYB transcription factor activity but not MYB protein levels (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
11792321
uniprot
proteins
pubmed
15082531
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16162816
uniprot
proteins
pubmed
1631139
uniprot
proteins
pubmed
17823980
uniprot
proteins
pubmed
1923521
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
2481264
uniprot
proteins
pubmed
2670562
uniprot
proteins
pubmed
2998780
uniprot
proteins
pubmed
3010282
uniprot
proteins
pubmed
3014527
uniprot
proteins
pubmed
3016644
uniprot
proteins
pubmed
3023843
uniprot
proteins
pubmed
3033638
uniprot
proteins
pubmed
3608990
uniprot
proteins
pubmed
7796266
uniprot
proteins
pubmed
8365401
uniprot
proteins
pubmed
8408047
uniprot
proteins
pubmed
8942977
uniprot
proteins
pubmed
9447996
uniprot
proteins
pubmed
9566892
uniprot
proteins
sequence_length
636
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16162816}.
uniprot
proteins