Hao2
entrez
84029
canonical
uniprot
Q07523
canonical
ensembl
ENSRNOG00000019470
resolver
ensembl
ENSRNOG00055032816
resolver
ensembl
ENSRNOG00060013867
resolver
ensembl
ENSRNOG00065031098
resolver
ensp
ENSRNOP00000040223
resolver
ensp
ENSRNOP00000071695
resolver
ensp
ENSRNOP00055046857
resolver
ensp
ENSRNOP00060018855
resolver
ensp
ENSRNOP00065044078
resolver
enst
ENSRNOT00000046942
resolver
enst
ENSRNOT00000091444
resolver
enst
ENSRNOT00055056753
resolver
enst
ENSRNOT00060023703
resolver
enst
ENSRNOT00065053630
resolver
genesymbol
Hao2
resolver
genesymbol_syn
Hao3
resolver
genesymbol_syn
Haox2
resolver
uniprot
A0A8L2UQG3
resolver
uniprot_entry
A0A8L2UQG3_RAT
resolver
uniprot_entry
HAOX2_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Is inhibited in vitro by CCPST (4-carboxy-5-(4-chlorophenyl)sulfanyl-1,2,3-thiadiazole). {ECO:0000269|PubMed:22342614}.
uniprot
proteins
amino_acid_sequence
MPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL
uniprot
proteins
ec_number
1.1.3.15
uniprot
proteins
function
FUNCTION: Oxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate, 2-hydroxyoctanoate, 2-hydroxyhexanoate and 2-hydroxybutanoate, to the corresponding 2-oxoacids (PubMed:15683236, PubMed:3061453, PubMed:8508789). Its role in the oxidation of 2-hydroxy fatty acids may contribute to the general pathway of fatty acid alpha-oxidation (By similarity). Can also use mandelate as substrate (PubMed:3061453). Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2 (PubMed:15683236, PubMed:3061453, PubMed:8508789). {ECO:0000250|UniProtKB:Q9NYQ3, ECO:0000269|PubMed:15683236, ECO:0000269|PubMed:3061453, ECO:0000269|PubMed:8508789}.
uniprot
proteins
mass_dalton
39201
uniprot
proteins
protein_family
FMN-dependent alpha-hydroxy acid dehydrogenase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15683236
uniprot
proteins
pubmed
1939137
uniprot
proteins
pubmed
22342614
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
3061453
uniprot
proteins
pubmed
8508789
uniprot
proteins
sequence_length
353
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome.
uniprot
proteins