Bhlha15
entrez
17341
canonical
uniprot
Q9QYC3
canonical
ensembl
ENSMUSG00000052271
resolver
ensp
ENSMUSP00000055493
resolver
enst
ENSMUST00000060747
resolver
genesymbol
Bhlha15
resolver
genesymbol_syn
Bhlhb8
resolver
genesymbol_syn
Mist1
resolver
uniprot
Q9QYE4
resolver
uniprot_entry
BHA15_MOUSE
resolver
uniprot_sec
Q9QYE4
resolver
amino_acid_sequence
MKTKNRPPRRRTPMQDTEATPGEQTPDRPQSGSGGSELTKGLRSRTARASGGRGEVSRRRQGSGGRRENSVQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEAPGPAPGPKLYQHYHHQQQQQQQQQQVAGAMLGVTEDQPQGHLQRYSTQIHSFREGS
uniprot
proteins
function
FUNCTION: Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated (PubMed:17612490). Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. {ECO:0000269|PubMed:15003629, ECO:0000269|PubMed:15665001, ECO:0000269|PubMed:17612490, ECO:0000269|PubMed:9482738}.
uniprot
proteins
mass_dalton
22150
uniprot
proteins
pubmed
10575209
uniprot
proteins
pubmed
11696558
uniprot
proteins
pubmed
15003629
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15665001
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17612490
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9073453
uniprot
proteins
pubmed
9482738
uniprot
proteins
sequence_length
197
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins