Slc26a4
entrez
23985
canonical
uniprot
Q9R155
canonical
ensembl
ENSMUSG00000020651
resolver
ensp
ENSMUSP00000001253
resolver
ensp
ENSMUSP00000196436
resolver
ensp
ENSMUSP00000196437
resolver
enst
ENSMUST00000001253
resolver
genesymbol
Slc26a4
resolver
genesymbol_syn
Pds
resolver
uniprot_entry
S26A4_MOUSE
resolver
amino_acid_sequence
MAARGGRSEPPQLAEYSCSYTVSRPVYSELAFQQQRERRLPERRTLRDSLARSCSCSRKRAFGVVKTLLPILDWLPKYRVKEWLLSDIISGVSTGLVGTLQGMAYALLAAVPVQFGLYSAFFPILTYFVFGTSRHISVGPFPVVSLMVGSVVLSMAPDDHFLVPSGNGSALNSTTLDTGTRDAARVLLASTLTLLVGIIQLVFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGILSIIYTLIEIFQNIGDTNIADFIAGLLTIIVCMAVKELNDRFKHRIPVPIPIEVIVTIIATAISYGANLEKNYNAGIVKSIPSGFLPPVLPSVGLFSDMLAASFSIAVVAYAIAVSVGKVYATKHDYVIDGNQEFIAFGISNVFSGFFSCFVATTALSRTAVQESTGGKTQVAGLISAVIVMVAIVALGRLLEPLQKSVLAAVVIANLKGMFMQVCDVPRLWKQNKTDAVIWVFTCIMSIILGLDLGLLAGLLFALLTVVLRVQFPSWNGLGSVPSTDIYKSITHYKNLEEPEGVKILRFSSPIFYGNVDGFKKCINSTVGFDAIRVYNKRLKALRRIQKLIKKGQLRATKNGIISDIGSSNNAFEPDEDVEEPEELNIPTKEIEIQVDWNSELPVKVNVPKVPIHSLVLDCGAVSFLDVVGVRSLRMIVKEFQRIDVNVYFALLQDDVLEKMEQCGFFDDNIRKDRFFLTVHDAILHLQNQVKSREGQDSLLETVARIRDCKDPLDLMEAEMNAEELDVQDEAMRRLAS
uniprot
proteins
function
FUNCTION: Sodium-independent transporter of chloride and iodide (By similarity). Mediates electroneutral iodide-chloride, iodide-bicarbonate and chloride-bicarbonate exchange with 1:1 stoichiometry (PubMed:11274445, PubMed:18565999). Mediates elctroneutral chloride-formate exchange (By similarity). {ECO:0000250|UniProtKB:Q9R154, ECO:0000269|PubMed:11274445, ECO:0000269|PubMed:18565999}.
uniprot
proteins
mass_dalton
85687
uniprot
proteins
protein_family
SLC26A/SulP transporter (TC 2.A.53) family
uniprot
proteins
pubmed
10449762
uniprot
proteins
pubmed
11274445
uniprot
proteins
pubmed
11459928
uniprot
proteins
pubmed
18565999
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
35601831
uniprot
proteins
sequence_length
780
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:11274445, ECO:0000269|PubMed:11459928, ECO:0000269|PubMed:18565999, ECO:0000269|PubMed:35601831}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:11459928}; Multi-pass membrane protein {ECO:0000269|PubMed:11459928}. Note=Localizes to the apical brush border of cells in the cortical collecting ducts of the kidney. {ECO:0000269|PubMed:11274445}.
uniprot
proteins
transmembrane_region
TRANSMEM 88..108; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 110..130; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 136..156; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 192..212; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 219..239; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 264..284; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 296..316; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 345..365; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 385..405; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 422..442; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 449..469; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 487..507; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins