Grm8
entrez
60590
canonical
uniprot
P70579
canonical
ensembl
ENSRNOG00000021468
resolver
ensp
ENSRNOP00000035953
resolver
enst
ENSRNOT00000031714
resolver
genesymbol
Grm8
resolver
genesymbol_syn
Gprc1h
resolver
genesymbol_syn
Mglur8
resolver
uniprot
F1LRA6
resolver
uniprot_entry
F1LRA6_RAT
resolver
uniprot_entry
GRM8_RAT
resolver
amino_acid_sequence
MVCEGKRLASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKERCPGYIGLCPRMVTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEYKIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTYISYSNHSI
uniprot
proteins
function
FUNCTION: G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
uniprot
proteins
mass_dalton
101867
uniprot
proteins
protein_family
G protein-coupled receptor 3 family
uniprot
proteins
pubmed
11122333
uniprot
proteins
pubmed
9016353
uniprot
proteins
sequence_length
908
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 584..608; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 621..641; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 648..668; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 696..716; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 747..768; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 782..803; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 819..843; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins