Tnfsf14
entrez
50930
canonical
uniprot
Q9QYH9
canonical
ensembl
ENSMUSG00000005824
resolver
ensp
ENSMUSP00000005976
resolver
enst
ENSMUST00000005976
resolver
genesymbol
Tnfsf14
resolver
genesymbol_syn
Light
resolver
genesymbol_syn
Tnlg1d
resolver
uniprot
A0A0U5JAA8
resolver
uniprot
Q059Y9
resolver
uniprot_entry
A0A0U5JAA8_MOUSE
resolver
uniprot_entry
TNF14_MOUSE
resolver
uniprot_sec
Q059Y9
resolver
amino_acid_sequence
MESVVQPSVFVVDGQTDIPFRRLEQNHRRRRCGTVQVSLALVLLLGAGLATQGWFLLRLHQRLGDIVAHLPDGGKGSWEKLIQDQRSHQANPAAHLTGANASLIGIGGPLLWETRLGLAFLRGLTYHDGALVTMEPGYYYVYSKVQLSGVGCPQGLANGLPITHGLYKRTSRYPKELELLVSRRSPCGRANSSRVWWDSSFLGGVVHLEAGEEVVVRVPGNRLVRPRDGTRSYFGAFMV
uniprot
proteins
function
FUNCTION: Cytokine that binds to TNFRSF3/LTBR. Activates NFKB and stimulates the proliferation of T-cells. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production (By similarity). {ECO:0000250|UniProtKB:O43557}.
uniprot
proteins
mass_dalton
26338
uniprot
proteins
post_translational_modification
PTM: The soluble form derives from the membrane form by proteolytic processing.
uniprot
proteins
protein_family
Tumor necrosis factor family
uniprot
proteins
pubmed
10700230
uniprot
proteins
pubmed
10894944
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
239
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 14, soluble form]: Secreted {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 38..58; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins