GPR173
entrez
54328
canonical
uniprot
Q9NS66
canonical
ensembl
ENSG00000184194
resolver
ensp
ENSP00000331600
resolver
ensp
ENSP00000565571
resolver
enst
ENST00000332582
resolver
enst
ENST00000895512
resolver
genesymbol
GPR173
resolver
genesymbol_syn
SREB3
resolver
hgnc
HGNC:18186
resolver
uniprot
B1B0A5
resolver
uniprot_entry
GP173_HUMAN
resolver
uniprot_sec
B1B0A5
resolver
amino_acid_sequence
MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYFLLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQLGRMFYAITLLFLLLWSPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWGTGGAPAPREPYCVM
uniprot
proteins
function
FUNCTION: Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity). In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth (PubMed:30933929). {ECO:0000250|UniProtKB:Q9JJH2, ECO:0000269|PubMed:30933929}.
uniprot
proteins
mass_dalton
41481
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10833454
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
30933929
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 27..47; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 60..80; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 98..118; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 140..160; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 189..209; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 288..308; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 323..343; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins