Ddi1
entrez
71829
canonical
uniprot
Q9DAF3
canonical
ensembl
ENSMUSG00000047619
resolver
ensp
ENSMUSP00000053223
resolver
enst
ENSMUST00000051706
resolver
genesymbol
Ddi1
resolver
uniprot_entry
DDI1_MOUSE
resolver
amino_acid_sequence
MLITVYCVRRDLTEVTFSLQVNPDFELSNFRVLCELESGVPAEEAQIVYMEQLLTDDHCSLGSYGLKDGDMVVLLQKDNVGLRTPGRTPNHPRADFTGSGSAVPGTSSSRHPHQHQHHYHHHQRIPSTQQAHGLASGENMTFAQELDSPALIRSMLLSNPHDLSLLKERNPALAEALLSGNLETFSQVLMEQQRERTLREQEMFRLYSTNPFDQETQARIEEEIRQQNIEENMNIAMEEAPESFGQVAMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWGGVAKGVGTQRIMGRVHLAQIQIEGDFLQCSFSILEEQPMDILLGLDMLRRHQCSIDLKKNVLVIGTTGSQTHFLPEGELPLCAKLLSGTVQEESSDREVGGTIKHPVKGPGRKKH
uniprot
proteins
ec_number
3.4.23.-
uniprot
proteins
function
FUNCTION: Probable aspartic protease (By similarity). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, for cellular survival following replication stress. Together or redundantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (By similarity). {ECO:0000250|UniProtKB:I7HUG0, ECO:0000250|UniProtKB:Q8WTU0}.
uniprot
proteins
mass_dalton
45713
uniprot
proteins
protein_family
DDI1 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
408
uniprot
proteins