Tspan10
entrez
208634
canonical
uniprot
Q8VCF5
canonical
ensembl
ENSMUSG00000039691
resolver
ensp
ENSMUSP00000041883
resolver
genesymbol
Tspan10
resolver
genesymbol_syn
Ocsp
resolver
uniprot
Q3UFN9
resolver
uniprot
Q3UFS7
resolver
uniprot
Q3UGA5
resolver
uniprot_entry
TSN10_MOUSE
resolver
uniprot_sec
Q3UFN9
resolver
uniprot_sec
Q3UFS7
resolver
uniprot_sec
Q3UGA5
resolver
amino_acid_sequence
MMKEEECSPLLSQDTAGREHPLTRNSPPTANIPCPAPWENQKGSWGCRCCPGAKRQASGEGQASSLPLSTGSNCVKYLIFLSNFLFSLPSLLALAAGLWGLTVKRSQGIGWGGPVPTDPMLMLVLGGLVVSVVSLSGCLGAFCENSCLLHWYCGAVLFCLALEALAGVLMVTLWKPLQDSLKYTLHAAIIHYWDDPDLHFLLDQVQLGLQCCGAVSYQDWQQNLYFNCSSPGVQACSLPASCCINPQEDGAVVNTQCGFGALGLDQNVAGQVVFLQGCWPALQEWLRGNTGAIGDCAVAVVMIQGTELLLAACLLRALAVHEAAEDIEAGPL
uniprot
proteins
function
FUNCTION: Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. {ECO:0000269|PubMed:23035126, ECO:0000269|PubMed:26668317}.
uniprot
proteins
mass_dalton
35313
uniprot
proteins
protein_family
Tetraspanin (TM4SF) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
23035126
uniprot
proteins
pubmed
26668317
uniprot
proteins
sequence_length
332
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 78..98; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 122..142; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 154..174; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 292..312; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins