Ecscr
entrez
68545
canonical
uniprot
Q3TZW0
canonical
ensembl
ENSMUSG00000073599
resolver
ensp
ENSMUSP00000095223
resolver
ensp
ENSMUSP00000118628
resolver
enst
ENSMUST00000133064
resolver
genesymbol
Ecscr
resolver
genesymbol_syn
Ecsm2
resolver
uniprot
C3RSF3
resolver
uniprot
G3UVV5
resolver
uniprot_entry
ECSCR_MOUSE
resolver
uniprot_entry
G3UVV5_MOUSE
resolver
uniprot_sec
C3RSF3
resolver
amino_acid_sequence
MRLGSAILGLLLLQGYSSQPTTTQTSQEILQKSSQVSLVSNQPVTPRSSTMDKQSLSLPDLMSFQPQKHTLGPGTGTPERSSSSSSSSSSRRGEASLDATPSPETTSLQTKKMTILLTILPTPTSESVLTVAAFGVISFIVILVVVVIILVSVVSLRFKCRKNKESEDPQKPGSSGLSESCSTANGEKDSITLISMRNINVNNSKGSMSAEKIL
uniprot
proteins
function
FUNCTION: Regulates endothelial chemotaxis and tube formation (By similarity). Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. {ECO:0000250, ECO:0000269|PubMed:19416853}.
uniprot
proteins
mass_dalton
22689
uniprot
proteins
post_translational_modification
PTM: May be heavily O-glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
ECSCR family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19416853
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
214
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 131..151; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins