Slc26a1
entrez
231583
canonical
uniprot
P58735
canonical
ensembl
ENSMUSG00000046959
resolver
ensp
ENSMUSP00000051561
resolver
ensp
ENSMUSP00000113185
resolver
ensp
ENSMUSP00000131282
resolver
ensp
ENSMUSP00000280928
resolver
ensp
ENSMUSP00000280929
resolver
ensp
ENSMUSP00000280930
resolver
enst
ENSMUST00000051757
resolver
enst
ENSMUST00000119270
resolver
enst
ENSMUST00000163328
resolver
genesymbol
Slc26a1
resolver
genesymbol_syn
Sat1
resolver
uniprot
G5E8U1
resolver
uniprot
Q3UPH6
resolver
uniprot
Q80WF6
resolver
uniprot_entry
G5E8U1_MOUSE
resolver
uniprot_entry
Q3UPH6_MOUSE
resolver
uniprot_entry
S26A1_MOUSE
resolver
uniprot_sec
Q80WF6
resolver
amino_acid_sequence
MDASPEPQQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPAIHWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPKNNDSTLNNSATTLIIGLQDCRRDCYAIRVATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHMLGVQIPRHQGLGMVVHTWLSLLQNVGQANICDVVTSALCLGVLLAAKELSDRYRHRLKVPIPTELFVIVVATIVSHFGQLHTRFDSRVAGNIPTGFVAPQVPDPKIMWRVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSTEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYRLTGLDAGHSATRKDQGPEVGVSNRSLVDGKDLGSVSSGAGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRRDYRALDITLLLACCSPSVRDTLRKGGFLGEEQGAENELLFPSVHSAVEAACARREELLAADSAL
uniprot
proteins
function
FUNCTION: Sodium-independent sulfate anion transporter (PubMed:12217875, PubMed:12590734, PubMed:20160351, PubMed:27210743). Can transport other anions including bicarbonate, thiosulfate and oxalate by mediating sulfate-hydrogencarbonate, sulfate-oxalate and oxalate-hydrogencarbonate anion exchange (PubMed:12217875, PubMed:12590734, PubMed:20160351, PubMed:27210743). Mediates sulfate-thiosulfate anion exchange (By similarity). {ECO:0000250|UniProtKB:Q9H2B4, ECO:0000269|PubMed:12217875, ECO:0000269|PubMed:12590734, ECO:0000269|PubMed:20160351, ECO:0000269|PubMed:27210743}.
uniprot
proteins
mass_dalton
75788
uniprot
proteins
mutagenesis
MUTAGEN 56; /note="A->T: Decreased sulfate-hydrogencarbonate exchange activity. Does not affect localization to plasma membrane."; /evidence="ECO:0000269|PubMed:27210743"; MUTAGEN 190; /note="T->M: Decreased sulfate-hydrogencarbonate exchange activity. Loss of localization to plasma membrane."; /evidence="ECO:0000269|PubMed:27210743"; MUTAGEN 363; /note="S->L: Decreased sulfate-hydrogencarbonate exchange activity. Increased accumulation of protein in ER."; /evidence="ECO:0000269|PubMed:27210743
uniprot
proteins
protein_family
SLC26A/SulP transporter (TC 2.A.53) family
uniprot
proteins
pubmed
12217875
uniprot
proteins
pubmed
12590734
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
20160351
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27210743
uniprot
proteins
sequence_length
704
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:27210743}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:P45380}; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 68..90; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 94..116; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 185..207; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 260..282; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 295..314; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 347..369; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 382..404; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 417..439; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 477..499; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins