Krt16
entrez
16666
canonical
uniprot
Q9Z2K1
canonical
ensembl
ENSMUSG00000053797
resolver
ensp
ENSMUSP00000007280
resolver
enst
ENSMUST00000007280
resolver
genesymbol
Krt16
resolver
genesymbol_syn
Krt1-16
resolver
uniprot
Q3SYP5
resolver
uniprot
Q3ZAW8
resolver
uniprot_entry
K1C16_MOUSE
resolver
uniprot_entry
Q3SYP5_MOUSE
resolver
uniprot_entry
Q3ZAW8_MOUSE
resolver
amino_acid_sequence
MATCSRQFTSSSSMKGSCGIGGGSSRMSSILAGGSCRAPSTCGGMSVTSSRFSSGGVCGIGGGYGGSFSSSSFGGGLGSGFGGRFDGFGGGFGAGLGGGLGGGIGDGLLVGSEKVTMQNLNDRLATYLDKVRALEEANRDLEVKIRDWYQRQRPTEIKDYSPYFKTIEDLKSKIIIATQENAQFTLQIDNARLAADDFRTKYENELFLRQSVEGDINGLRKVLDELTLSRADLEMQIENLREELAFLKKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDVEAWFLRKTEELNKEVASNSDLIQSNRSEVAELRRVFQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLISSVEEQLAQLRCEMEQQSQEYNILLDVKTRLEQEIATYRRLLDGENIHSSSQHSSGQSYSSREVFSSSSRQPRSILKEQGSTSFSQSQSQSSRD
uniprot
proteins
function
FUNCTION: Structural component of intermediate filaments in epithelial keratinocytes. Forms heteropolymers with type II keratins KRT6A and KRT6B, assembling into keratin intermediate filament networks that contribute to cytoskeletal resilience of palm, sole, nail bed and oral mucosa (PubMed:11029038, PubMed:22336941, PubMed:24218583). Regulates epidermal innate immunity and inflammatory signaling in response to barrier disruption (PubMed:24218583). Required for normal palmoplantar epidermal differentiation and nail unit structure (PubMed:22336941). {ECO:0000269|PubMed:11029038, ECO:0000269|PubMed:22336941, ECO:0000269|PubMed:24218583}.
uniprot
proteins
mass_dalton
51606
uniprot
proteins
protein_family
Intermediate filament family
uniprot
proteins
pubmed
11029038
uniprot
proteins
pubmed
11408584
uniprot
proteins
pubmed
12445204
uniprot
proteins
pubmed
16702408
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22336941
uniprot
proteins
pubmed
24218583
uniprot
proteins
pubmed
26758872
uniprot
proteins
pubmed
8636216
uniprot
proteins
pubmed
9822705
uniprot
proteins
sequence_length
469
uniprot
proteins