Msra
entrez
110265
canonical
uniprot
Q9D6Y7
canonical
ensembl
ENSMUSG00000054733
resolver
ensp
ENSMUSP00000065754
resolver
ensp
ENSMUSP00000147689
resolver
ensp
ENSMUSP00000148189
resolver
ensp
ENSMUSP00000213862
resolver
enst
ENSMUST00000210363
resolver
genesymbol
Msra
resolver
uniprot
A0A1B0GT40
resolver
uniprot
Q5EBQ7
resolver
uniprot
Q91WK9
resolver
uniprot
Q9DCY2
resolver
uniprot_entry
A0A1B0GT40_MOUSE
resolver
uniprot_entry
MSRA_MOUSE
resolver
uniprot_sec
Q5EBQ7
resolver
uniprot_sec
Q91WK9
resolver
uniprot_sec
Q9DCY2
resolver
amino_acid_sequence
MLSASRRALQLLSSANPVRRMGDSASKVISAEEALPGRTEPIPVTAKHHVSGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGHTRNPTYKEVCSEKTGHAEVVRVVYRPEHISFEELLKVFWENHDPTQGMRQGNDFGTQYRSAVYPTSAVQMEAALRSKEEYQKVLSKHNFGPITTDIREGQVFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPMAIKK
uniprot
proteins
ec_number
1.8.4.11
uniprot
proteins
function
FUNCTION: Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Plays a crucial role in repairing oxidized methionine residues in key lens proteins, such as alpha-crystallin (CRYAA/CRYAB) and cytochrome c (CYCS), thereby restoring their function and maintaining lens transparency. {ECO:0000269|PubMed:21079812}.; FUNCTION: [Isoform 1]: Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. {ECO:0000269|PubMed:15924425}.; FUNCTION: [Isoform 2]: Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. {ECO:0000269|PubMed:20368336, ECO:0000269|PubMed:30529269}.
uniprot
proteins
mass_dalton
25988
uniprot
proteins
protein_family
MsrA Met sulfoxide reductase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15924425
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20368336
uniprot
proteins
pubmed
21079812
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
30529269
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:21079812}. Cytoplasm {ECO:0000269|PubMed:21079812}.; SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:15924425, ECO:0000269|PubMed:20368336}. Cytoplasm {ECO:0000269|PubMed:15924425}. Nucleus {ECO:0000269|PubMed:15924425}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:20368336}. Membrane {ECO:0000250|UniProtKB:Q9UJ68}; Lipid-anchor {ECO:0000250|UniProtKB:Q9UJ68}.
uniprot
proteins