FRAT1
entrez
10023
canonical
uniprot
Q92837
canonical
ensembl
ENSG00000165879
resolver
ensp
ENSP00000360060
resolver
enst
ENST00000371021
resolver
genesymbol
FRAT1
resolver
hgnc
HGNC:3944
resolver
uniprot
Q5JTI1
resolver
uniprot
Q8NE74
resolver
uniprot
Q8TDW9
resolver
uniprot_entry
FRAT1_HUMAN
resolver
uniprot_sec
Q5JTI1
resolver
uniprot_sec
Q8NE74
resolver
uniprot_sec
Q8TDW9
resolver
amino_acid_sequence
MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS
uniprot
proteins
function
FUNCTION: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. {ECO:0000269|PubMed:12556519}.
uniprot
proteins
mass_dalton
29093
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250}.
uniprot
proteins
protein_family
GSK-3-binding protein family
uniprot
proteins
pubmed
11738041
uniprot
proteins
pubmed
11894125
uniprot
proteins
pubmed
12556519
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
9034327
uniprot
proteins
sequence_length
279
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins