C1qtnf5
entrez
315598
canonical
uniprot
Q5FVH0
canonical
ensembl
ENSRNOG00000007613
resolver
ensembl
ENSRNOG00055020186
resolver
ensembl
ENSRNOG00060021927
resolver
ensembl
ENSRNOG00065022966
resolver
ensp
ENSRNOP00000010127
resolver
ensp
ENSRNOP00055027929
resolver
ensp
ENSRNOP00060031321
resolver
ensp
ENSRNOP00065031875
resolver
enst
ENSRNOT00055034465
resolver
enst
ENSRNOT00060037995
resolver
enst
ENSRNOT00065039240
resolver
genesymbol
C1qtnf5
resolver
genesymbol_syn
Ctrp5
resolver
uniprot_entry
C1QT5_RAT
resolver
amino_acid_sequence
MRPLLALLLLGLASGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGEPGPRGEAGPVGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHYDATTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQFFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA
uniprot
proteins
function
FUNCTION: Involved in cellular energy homeostasis through the regulation of 5'-AMP-activated protein kinase (AMPK) phosphorylation and activation (PubMed:19651784). In myocytes, it induces adiponectin receptors-independent AMPK phosphorylation and activation, thereby increasing the phosphorylation of acetyl-CoA carboxylase (ACC) and stimulating fatty acid oxidation and glucose uptake (PubMed:19651784). In the retinal pigment epithelium (RPE), it acts as antagonist of adiponectin receptor protein 1 (ADIPOR1) and negatively regulates ADIPOR1-dependent AMPK activation (By similarity). {ECO:0000250|UniProtKB:Q9BXJ0, ECO:0000269|PubMed:19651784}.
uniprot
proteins
mass_dalton
25334
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19651784
uniprot
proteins
sequence_length
243
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:Q8K479}. Secreted {ECO:0000269|PubMed:19651784}. Note=Associated with the lateral and apical membranes of the ocular ciliary body and retinal pigment epithelium. {ECO:0000250|UniProtKB:Q8K479}.
uniprot
proteins