AP3M2
entrez
10947
canonical
uniprot
P53677
canonical
ensembl
ENSG00000070718
resolver
ensp
ENSP00000380132
resolver
ensp
ENSP00000428787
resolver
ensp
ENSP00000430616
resolver
genesymbol
AP3M2
resolver
hgnc
HGNC:570
resolver
uniprot
A0A384NYL6
resolver
uniprot
B2RCR0
resolver
uniprot
D3DSY2
resolver
uniprot
Q7Z472
resolver
uniprot_entry
A0A384NYL6_HUMAN
resolver
uniprot_entry
AP3M2_HUMAN
resolver
uniprot_sec
B2RCR0
resolver
uniprot_sec
D3DSY2
resolver
uniprot_sec
Q7Z472
resolver
amino_acid_sequence
MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVIEEIDAIIDKSGSTITAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHNISFRDSSSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMSLQAGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT
uniprot
proteins
function
FUNCTION: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
uniprot
proteins
mass_dalton
46977
uniprot
proteins
protein_family
Adaptor complexes medium subunit family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
7601449
uniprot
proteins
sequence_length
418
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250}.
uniprot
proteins