Pdss2
entrez
71365
canonical
uniprot
Q33DR3
canonical
ensembl
ENSMUSG00000038240
resolver
ensp
ENSMUSP00000093393
resolver
ensp
ENSMUSP00000124864
resolver
ensp
ENSMUSP00000199055
resolver
ensp
ENSMUSP00000199058
resolver
ensp
ENSMUSP00000199060
resolver
ensp
ENSMUSP00000199072
resolver
genesymbol
Pdss2
resolver
genesymbol_syn
Dlp1
resolver
uniprot
B2RWA7
resolver
uniprot
B2RWF3
resolver
uniprot
Q3USU6
resolver
uniprot
Q9D3K7
resolver
uniprot_entry
DLP1_MOUSE
resolver
uniprot_sec
B2RWA7
resolver
uniprot_sec
B2RWF3
resolver
uniprot_sec
Q3USU6
resolver
uniprot_sec
Q9D3K7
resolver
amino_acid_sequence
MSLRQLLLRLSGYLGASGPPSRHWWYFRSLDSISSAGSWRGRSSRSPAHWNQVVSEAEKIVGYPASFMSLRCLLSDELSNIAMQVRKLVGTGHPLLTTARALVHDSRHNLQLRGLVVLLISKAAGPSTRNAACQNYDMVSGVYSCQRSLAEITELIHTALLVHRGIVNLSELQSSDGPLKDMQFGNKIAILSGDFLLANACNGLALLQNTKVVELLSSALMDLVHGVYQENSASTKENSIPDDIGISTWKEQTFLSHCALLAKSCQAAMELAKHDAAVQDMAFQYGKHMAMSHKINADLQPFIKDKASDSKTFNLNSAPVVLHQEFLGRDLWIKQIGEAQEKGSLNYSKLRETIKAGKGVTSAIDLCRYHGNKALEALESFPPSEARSALENIVFAVTRFS
uniprot
proteins
ec_number
2.5.1.91
uniprot
proteins
function
FUNCTION: Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone (PubMed:16262699). Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively (PubMed:16262699). The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry (PubMed:16262699). May play a role during cerebellar development (PubMed:21871565). May regulate mitochondrial respiratory chain function (PubMed:18437205). {ECO:0000269|PubMed:16262699, ECO:0000269|PubMed:18437205, ECO:0000269|PubMed:21871565}.
uniprot
proteins
mass_dalton
43980
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis. {ECO:0000269|PubMed:16262699}.
uniprot
proteins
protein_family
FPP/GGPP synthase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16262699
uniprot
proteins
pubmed
18437205
uniprot
proteins
pubmed
21871565
uniprot
proteins
sequence_length
401
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
uniprot
proteins