SUN3
entrez
256979
canonical
uniprot
Q8TAQ9
canonical
ensembl
ENSG00000164744
resolver
ensp
ENSP00000297325
resolver
ensp
ENSP00000378939
resolver
ensp
ENSP00000410204
resolver
genesymbol
SUN3
resolver
genesymbol_syn
SUNC1
resolver
hgnc
HGNC:22429
resolver
uniprot
A4D2F3
resolver
uniprot
B4DXK1
resolver
uniprot
D3DVM3
resolver
uniprot
E7EWC8
resolver
uniprot
Q4F965
resolver
uniprot
Q7Z4U8
resolver
uniprot_entry
SUN3_HUMAN
resolver
uniprot_sec
A4D2F3
resolver
uniprot_sec
B4DXK1
resolver
uniprot_sec
D3DVM3
resolver
uniprot_sec
E7EWC8
resolver
uniprot_sec
Q4F965
resolver
uniprot_sec
Q7Z4U8
resolver
amino_acid_sequence
MSGKTKARRAAMFFRRCSEDASGSASGNALLSEDENPDANGVTRSWKIILSTMLTLTFLLVGLLNHQWLKETDVPQKSRQLYAIIAEYGSRLYKYQARLRMPKEQLELLKKESQNLENNFRQILFLIEQIDVLKALLRDMKDGMDNNHNWNTHGDPVEDPDHTEEVSNLVNYVLKKLREDQVEMADYALKSAGASIIEAGTSESYKNNKAKLYWHGIGFLNHEMPPDIILQPDVYPGKCWAFPGSQGHTLIKLATKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGITKKCEGEEIFLGQFIYNKTGTTVQTFELQHAVSEYLLCVKLNIFSNWGHPKYTCLYRFRVHGTPGKHI
uniprot
proteins
function
FUNCTION: As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenesis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette. {ECO:0000250|UniProtKB:Q5SS91}.
uniprot
proteins
mass_dalton
40503
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
26244732
uniprot
proteins
sequence_length
357
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus envelope {ECO:0000250|UniProtKB:Q5SS91}. Nucleus inner membrane {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 48..64; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins