Slc47a2
entrez
380701
canonical
uniprot
Q3V050
canonical
ensembl
ENSMUSG00000069855
resolver
ensp
ENSMUSP00000090710
resolver
ensp
ENSMUSP00000120907
resolver
enst
ENSMUST00000093029
resolver
enst
ENSMUST00000134423
resolver
genesymbol
Slc47a2
resolver
genesymbol_syn
Mate2
resolver
uniprot
B2RXN1
resolver
uniprot
Q5SS46
resolver
uniprot_entry
S47A2_MOUSE
resolver
uniprot_sec
B2RXN1
resolver
uniprot_sec
Q5SS46
resolver
amino_acid_sequence
MEPAEDSLGATIQPPELVRVPRGRSLRILLGLRGALSPDVRREAAALVALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQGIIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGSAWANTTSQFFLSALLFLYVWWKRIHIHTWGGWTRECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVAEQAQVRAGLKSTKELIPTPADLPILEREVMDGVILPDIIRPESQTGQLVVEENSQCAVPTVGEVLTGRQLVFYRGMALTVSVAVLIAGIVVRVFNDRG
uniprot
proteins
function
FUNCTION: Multidrug efflux pump that functions as a H(+)/organic cation antiporter (PubMed:17715386). May mediate testosterone efflux from the Leydig cells in the testes (PubMed:17715386). {ECO:0000269|PubMed:17715386, ECO:0000303|PubMed:17715386}.
uniprot
proteins
mass_dalton
61789
uniprot
proteins
protein_family
Multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17715386
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
573
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:17715386}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 47..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 123..143; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 162..182; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 197..217; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 226..246; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 267..286; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 305..325; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 346..366; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 380..400; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 416..436; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 444..464; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 546..566; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins