Gjb4
entrez
14621
canonical
uniprot
Q02738
canonical
ensembl
ENSMUSG00000046623
resolver
ensp
ENSMUSP00000053307
resolver
ensp
ENSMUSP00000101696
resolver
ensp
ENSMUSP00000344029
resolver
enst
ENSMUST00000060419
resolver
enst
ENSMUST00000106090
resolver
genesymbol
Gjb4
resolver
genesymbol_syn
Cxn-30.3
resolver
uniprot
Q8C677
resolver
uniprot_entry
CXB4_MOUSE
resolver
uniprot_entry
Q8C677_MOUSE
resolver
amino_acid_sequence
MNWGFLQGILSGVNKYSTALGRIWLSVVFIFRVLVYVVAAEEVWDDDQKDFICNTKQPGCPNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHRLKHGPNAPALYSNLSKKRGGLWWTYLLSLIFKAAVDSGFLYIFHCIYKDYDMPRVVACSVTPCPHTVDCYIARPTEKKVFTYFMVVTAAICILLNLSEVVYLVGKRCMEVFRPRRRKASRRHQLPDTCPPYVISKGGHPQDESVILTKAGMATVDAGVYP
uniprot
proteins
function
FUNCTION: Structural component of gap junctions (PubMed:15692151). Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (PubMed:15692151). {ECO:0000250|UniProtKB:P29033, ECO:0000269|PubMed:15692151}.
uniprot
proteins
mass_dalton
30389
uniprot
proteins
protein_family
Beta-type (group I) subfamily
uniprot
proteins
protein_family
Connexin family
uniprot
proteins
pubmed
1512260
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15692151
uniprot
proteins
sequence_length
266
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:15692151}; Multi-pass membrane protein {ECO:0000305}. Cell junction, gap junction {ECO:0000269|PubMed:15692151}. Note=Colocalizes with GJB2 at gap junction plaques in the cochlea. {ECO:0000269|PubMed:15692151}.
uniprot
proteins
transmembrane_region
TRANSMEM 21..40; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033"; TRANSMEM 74..94; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033"; TRANSMEM 131..151; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033"; TRANSMEM 185..205; /note="Helical"; /evidence="ECO:0000250|UniProtKB:P29033
uniprot
proteins