Ccn2
entrez
14219
canonical
uniprot
P29268
canonical
ensembl
ENSMUSG00000019997
resolver
ensp
ENSMUSP00000020171
resolver
enst
ENSMUST00000020171
resolver
genesymbol
Ccn2
resolver
genesymbol_syn
Ctgf
resolver
genesymbol_syn
Fisp-12
resolver
genesymbol_syn
Fisp12
resolver
genesymbol_syn
Hcs24
resolver
genesymbol_syn
betaIG-M2
resolver
uniprot
G5E830
resolver
uniprot
Q922U0
resolver
uniprot_entry
CCN2_MOUSE
resolver
uniprot_sec
G5E830
resolver
uniprot_sec
Q922U0
resolver
amino_acid_sequence
MLASVAGPISLALVLLALCTRPAMGQDCSAQCQCAAEAAPHCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCVFGGSVYRSGESFQSSCKYQCTCLDGAVGCVPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDRTAVGPALAAYRLEDTFGPDPTMMRANCLVQTTEWSACSKTCGMGISTRVTNDNTFCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKIAKPVKFELSGCTSVKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEIMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
uniprot
proteins
function
FUNCTION: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis (PubMed:39414788). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity). {ECO:0000250|UniProtKB:P29279, ECO:0000269|PubMed:10082563, ECO:0000269|PubMed:39414788, ECO:0000269|PubMed:9184077}.
uniprot
proteins
mass_dalton
37824
uniprot
proteins
protein_family
CCN family
uniprot
proteins
pubmed
10082563
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1888698
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
2029337
uniprot
proteins
pubmed
30232710
uniprot
proteins
pubmed
39414788
uniprot
proteins
pubmed
9184077
uniprot
proteins
sequence_length
348
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:9184077}. Secreted {ECO:0000269|PubMed:9184077}.
uniprot
proteins