CPLX2
entrez
10814
canonical
uniprot
Q6PUV4
canonical
ensembl
ENSG00000145920
resolver
ensp
ENSP00000352544
resolver
ensp
ENSP00000377346
resolver
ensp
ENSP00000421106
resolver
ensp
ENSP00000421825
resolver
ensp
ENSP00000423612
resolver
ensp
ENSP00000569684
resolver
ensp
ENSP00000569685
resolver
ensp
ENSP00000569686
resolver
ensp
ENSP00000569687
resolver
ensp
ENSP00000569688
resolver
ensp
ENSP00000569689
resolver
ensp
ENSP00000641213
resolver
enst
ENST00000359546
resolver
enst
ENST00000393745
resolver
enst
ENST00000515094
resolver
enst
ENST00000899625
resolver
enst
ENST00000899626
resolver
enst
ENST00000899627
resolver
enst
ENST00000899628
resolver
enst
ENST00000899629
resolver
enst
ENST00000899630
resolver
enst
ENST00000971154
resolver
genesymbol
CPLX2
resolver
hgnc
HGNC:2310
resolver
uniprot
B2RAG2
resolver
uniprot
O09056
resolver
uniprot
Q13329
resolver
uniprot
Q28184
resolver
uniprot
Q52M15
resolver
uniprot
Q64386
resolver
uniprot_entry
CPLX2_HUMAN
resolver
uniprot_sec
B2RAG2
resolver
uniprot_sec
O09056
resolver
uniprot_sec
Q13329
resolver
uniprot_sec
Q28184
resolver
uniprot_sec
Q52M15
resolver
uniprot_sec
Q64386
resolver
amino_acid_sequence
MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK
uniprot
proteins
function
FUNCTION: Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis (By similarity). {ECO:0000250|UniProtKB:P84086, ECO:0000250|UniProtKB:P84088}.
uniprot
proteins
mass_dalton
15394
uniprot
proteins
protein_family
Complexin/synaphin family
uniprot
proteins
pubmed
11483314
uniprot
proteins
pubmed
11576753
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15906159
uniprot
proteins
pubmed
16162394
uniprot
proteins
pubmed
7553862
uniprot
proteins
pubmed
9853440
uniprot
proteins
sequence_length
134
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P84087}. Presynapse {ECO:0000250|UniProtKB:P84087}. Nucleus {ECO:0000250|UniProtKB:P84087}. Perikaryon {ECO:0000250|UniProtKB:P84087}. Note=Translocated from the perikaryon to the presynaptic terminals during maturation of neuronal cells. In mast cells, cytosol and nucleus. Becomes enriched near plasma membrane following stimulation. {ECO:0000250|UniProtKB:P84087}.
uniprot
proteins