CCL16
entrez
6360
canonical
uniprot
O15467
canonical
ensembl
ENSG00000275095
resolver
ensembl
ENSG00000275152
resolver
ensp
ENSP00000478024
resolver
ensp
ENSP00000482168
resolver
enst
ENST00000611905
resolver
enst
ENST00000621559
resolver
genesymbol
CCL16
resolver
genesymbol_syn
ILINCK
resolver
genesymbol_syn
NCC4
resolver
genesymbol_syn
SCYA16
resolver
hgnc
HGNC:10614
resolver
uniprot
Q4KKU0
resolver
uniprot_entry
CCL16_HUMAN
resolver
uniprot_sec
Q4KKU0
resolver
amino_acid_sequence
MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ
uniprot
proteins
function
FUNCTION: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
uniprot
proteins
mass_dalton
13600
uniprot
proteins
protein_family
Intercrine beta (chemokine CC) family
uniprot
proteins
pubmed
10213461
uniprot
proteins
pubmed
10235110
uniprot
proteins
pubmed
10671294
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
9545580
uniprot
proteins
pubmed
9596672
uniprot
proteins
pubmed
9642106
uniprot
proteins
sequence_length
120
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins