ARF4
entrez
378
canonical
uniprot
P18085
canonical
ensembl
ENSG00000168374
resolver
ensp
ENSP00000306010
resolver
ensp
ENSP00000618703
resolver
enst
ENST00000303436
resolver
enst
ENST00000948644
resolver
genesymbol
ARF4
resolver
genesymbol_syn
ARF2
resolver
hgnc
HGNC:655
resolver
uniprot
B2R7J7
resolver
uniprot
P21371
resolver
uniprot_entry
ARF4_HUMAN
resolver
uniprot_sec
B2R7J7
resolver
uniprot_sec
P21371
resolver
amino_acid_sequence
MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR
uniprot
proteins
function
FUNCTION: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Part of the ciliary targeting complex containing Rab11, ASAP1, Rabin8/RAB3IP, RAB11FIP3 and ARF4, which direct preciliary vesicle trafficking to mother centriole and ciliogenesis initiation (PubMed:25673879). {ECO:0000269|PubMed:25673879}.
uniprot
proteins
mass_dalton
20511
uniprot
proteins
protein_family
Arf family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
10524252
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1899243
uniprot
proteins
pubmed
2107548
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25255805
uniprot
proteins
pubmed
25673879
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26258637
uniprot
proteins
sequence_length
180
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:25673879}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
uniprot
proteins