Ndc1
entrez
362557
canonical
uniprot
Q6AXN4
canonical
ensembl
ENSRNOG00000010620
resolver
ensp
ENSRNOP00000014275
resolver
genesymbol
Ndc1
resolver
genesymbol_syn
Tmem48
resolver
uniprot_entry
NDC1_RAT
resolver
amino_acid_sequence
MATAASGPCAGGSPRDILWRVLGWRIVTSVVWSVLLLPVCITAFIVFSSIDLFHPIQWLSDSLNEFYSSQVIFYLLLLAVVIIIISIFNVEFYTVVPSIPGSRLALIARILHPQQLTHSFIHAVMGMAVAWCAAIMTKGQSRSLVVPCTGTESLDSPAAQTCMNEYHLFFLLSGAFMGYSYSLLYFINNMNYLPFPIIQQYKFLRFRRSLLLLVKHSCVESLFMVRNFCIVYYFFGHIPKAWISTALDLRTDEQAHRPLDTIGGLLNVSLLYHVWLCGVFLLMTWYISWILFKIYATEAYMFPVQPPFAEESDECLPKVLNSNPPLIIKYLALQDLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLSLLNDMTQKLVLYQEAAATNGRMYSSYSVEPKRLSSPEETAFQTPKPSQMPSVPPLVKTSLFSPKLSTPDGSSPFGTPFGSSVVNRMAGIFDVNTCCGSPQSPQLVRRGPRLWTHTSDQQVSAVSNPSPCASVTAEGKTVRQPSVLYSWIQNKREQIKNFLSKRVLIMYFFSKHPEASIQAVFSDAQMHIWALEGLSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRTSGSLVDTSYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASAEHQKRLQQFLEFKE
uniprot
proteins
function
FUNCTION: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity). {ECO:0000250|UniProtKB:Q9BTX1}.
uniprot
proteins
mass_dalton
75713
uniprot
proteins
post_translational_modification
PTM: Phosphorylated. {ECO:0000250}.
uniprot
proteins
protein_family
NDC1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16600873
uniprot
proteins
sequence_length
673
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nuclear pore complex {ECO:0000250}. Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Central core structure of the nuclear pore complex. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..46; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 72..92; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 116..136; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 167..187; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 227..247; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 274..294; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins