Tmem86b
entrez
68255
canonical
uniprot
Q497J1
canonical
ensembl
ENSMUSG00000045282
resolver
ensp
ENSMUSP00000060237
resolver
ensp
ENSMUSP00000215413
resolver
ensp
ENSMUSP00000361469
resolver
enst
ENSMUST00000055085
resolver
genesymbol
Tmem86b
resolver
uniprot_entry
TM86B_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Competitively inhibited by lysophosphatidic acid. {ECO:0000250|UniProtKB:Q8N661}.
uniprot
proteins
amino_acid_sequence
MDARKEGLPLETLFSDQYPQVRRWLAPFILACSLYFLLWIPVDQPSWVSALIKCQPILCLVVFLWAVAPGGSSTWLLQGALVCSAVGDACLIWPEAFFYGTAAFSVAHLFYLGAFGLTPLQPGLLLCTTLASLTYYSFLLLHLEQGMVLPVMAYGLILNSMLWRSLVWGGSASWGAVLFTFSDGVLAWDTFVYSLPFARLVTMSTYYAAQLLLILSALRNPGLKTH
uniprot
proteins
ec_number
3.3.2.2
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of the vinyl ether bond of choline or ethanolamine lysoplasmalogens, forming fatty aldehyde and glycerophosphocholine or glycerophosphoethanolamine, respectively and is specific for the sn-2-deacylated (lyso) form of plasmalogen. {ECO:0000250|UniProtKB:B0BNF0}.
uniprot
proteins
mass_dalton
24989
uniprot
proteins
protein_family
TMEM86 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21515882
uniprot
proteins
sequence_length
226
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D8N3}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:Q8N661}.
uniprot
proteins
transmembrane_region
TRANSMEM 24..40; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 47..68; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 75..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..117; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 124..140; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 147..163; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 172..188; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 200..218; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins