THNSL2
entrez
55258
canonical
uniprot
Q86YJ6
canonical
ensembl
ENSG00000144115
resolver
ensp
ENSP00000327323
resolver
ensp
ENSP00000339563
resolver
ensp
ENSP00000366464
resolver
ensp
ENSP00000501447
resolver
ensp
ENSP00000501453
resolver
ensp
ENSP00000665058
resolver
ensp
ENSP00000665060
resolver
ensp
ENSP00000687906
resolver
ensp
ENSP00000687910
resolver
ensp
ENSP00000787108
resolver
ensp
ENSP00000787109
resolver
ensp
ENSP00000795368
resolver
enst
ENST00000377254
resolver
genesymbol
THNSL2
resolver
hgnc
HGNC:25602
resolver
uniprot
A0A0A0MRU2
resolver
uniprot
A8K0C1
resolver
uniprot
B3KTB1
resolver
uniprot
B5MDX8
resolver
uniprot
B7WPF8
resolver
uniprot
D9ZZB8
resolver
uniprot
Q6P2M7
resolver
uniprot
Q6PI27
resolver
uniprot
Q9NV54
resolver
uniprot_entry
A0A0A0MRU2_HUMAN
resolver
uniprot_entry
A8K0C1_HUMAN
resolver
uniprot_entry
THNS2_HUMAN
resolver
uniprot_sec
B3KTB1
resolver
uniprot_sec
B5MDX8
resolver
uniprot_sec
B7WPF8
resolver
uniprot_sec
D9ZZB8
resolver
uniprot_sec
Q6P2M7
resolver
uniprot_sec
Q6PI27
resolver
uniprot_sec
Q9NV54
resolver
amino_acid_sequence
MWYVSTRGVAPRVNFEGALFSGYAPDGGLFMPEELPQLDRGTLCQWSTLSYPGLVKELCALFIGSELLPKDELNDLIDRAFSRFRHREVVHLSRLRNGLNVLELWHGVTYAFKDLSLSCTTQFLQYFLEKREKHVTVVVGTSGDTGSAAIESVQGAKNMDIIVLLPKGHCTKIQELQMTTVLKQNVHVFGVEGNSDELDEPIKTVFADVAFVKKHNLMSLNSINWSRVLVQMAHHFFAYFQCTPSLDTHPLPLVEVVVPTGAAGNLAAGYIAQKIGLPIRLVVAVNRNDIIHRTVQQGDFSLSEAVKSTLASAMDIQVPYNMERVFWLLSGSDSQVTRALMEQFERTQSVNLPKELHSKLSEAVTSVSVSDEAITQTMGRCWDENQYLLCPHSAVAVNYHYQQIDRQQPSTPRCCLAPASAAKFPEAVLAAGLTPETPAEIVALEHKETRCTLMRRGDNWMLMLRDTIEDLSRQWRSHALNTSQ
uniprot
proteins
ec_number
4.2.3.-
uniprot
proteins
function
FUNCTION: [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). {ECO:0000250}.; FUNCTION: [Isoform SOFAT]: Potent inducer of osteoblastic production of IL6. May act to exacerbate inflammation and/or bone turnover under inflammatory conditions. {ECO:0000269|PubMed:19877052}.
uniprot
proteins
mass_dalton
54116
uniprot
proteins
protein_family
Threonine synthase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
19877052
uniprot
proteins
sequence_length
484
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform SOFAT]: Secreted. Note=Secreted by activated T-cells via a calcineurin-independent pathway.
uniprot
proteins