Ptprr
entrez
94202
canonical
uniprot
O08617
canonical
ensembl
ENSRNOG00000004483
resolver
ensp
ENSRNOP00000006401
resolver
ensp
ENSRNOP00000070648
resolver
enst
ENSRNOT00000006401
resolver
genesymbol
Ptprr
resolver
genesymbol_syn
Ptp
resolver
uniprot
G3V6L5
resolver
uniprot
Q5FWV8
resolver
uniprot
Q62695
resolver
uniprot
Q63419
resolver
uniprot_entry
G3V6L5_RAT
resolver
uniprot_entry
PTPRR_RAT
resolver
uniprot_entry
Q5FWV8_RAT
resolver
uniprot_sec
Q62695
resolver
uniprot_sec
Q63419
resolver
amino_acid_sequence
MRRAVGFPALCLLLNLHAAGCFSRNNDHFLAIRQKKSWKPMFIYDHSQDIKKSLDIAQEAYKHNYPAPSEVQISKRHQIVDSAFPRPAYDPSLNLLAASGQDLEIENLPIPAANVIVVTLQMDIDKLNITLLRIFRQGVAAALGLLPQQVHINRLIEKKSQIELFVSPGNRKPGEPQALQAEEVLRSLNVDVLRQSLPQFGSIDVSPEKNVLQGQHEADKIWSKEGFYAVVIFLSIFIIIVTCLMIIYRLKERLQLSFRQDKEKNQEIHLSPIALQQAQSEAKAAHSMVQPDQAPKVLNVVVDPQGQCTPEIRNTASTSVCPSPFRMKPIGLQERRGSNVSLTLDMSSLGNVEPFVAVSTPREKVAMEYLQSASRVLTSPQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNITDPLSTYINANYIRGYSGKEKAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVIGVNECDNYTIRNLVLKRGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASEGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFESRLSPETVQ
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
73907
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
protein_family
Receptor class 7 subfamily
uniprot
proteins
pubmed
7557444
uniprot
proteins
pubmed
7814416
uniprot
proteins
sequence_length
656
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 226..248; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins