Cyp4x1
entrez
81906
canonical
uniprot
Q6A152
canonical
ensembl
ENSMUSG00000047155
resolver
ensp
ENSMUSP00000059545
resolver
ensp
ENSMUSP00000102155
resolver
enst
ENSMUST00000051400
resolver
genesymbol
Cyp4x1
resolver
uniprot
Q2HJC6
resolver
uniprot
Q8BYS0
resolver
uniprot_entry
CP4X1_MOUSE
resolver
uniprot_sec
Q2HJC6
resolver
uniprot_sec
Q8BYS0
resolver
amino_acid_sequence
MEASWLETRWARPLHLALVFCLALVLMQAMKLYLRRQRLLRDLSPFPGPPAHWLLGHQKFLQEDNMETLDEIVKKHPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKMQYLHQLLTPCIGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQYTEKIIQDRKKILKNQVKQDDTQTSQIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGSSITWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALILLHFQVAPDLTRPPAFSSHTVLRPKHGIYLHLKKLLEC
uniprot
proteins
ec_number
1.14.14.-
uniprot
proteins
function
FUNCTION: A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling. Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). {ECO:0000250|UniProtKB:Q8N118}.
uniprot
proteins
mass_dalton
58557
uniprot
proteins
protein_family
Cytochrome P450 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16478468
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
507
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305|PubMed:16478468}; Single-pass membrane protein {ECO:0000255}. Microsome membrane {ECO:0000269|PubMed:16478468}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 14..34; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins