Cnih2
entrez
361705
canonical
uniprot
Q5BJU5
canonical
ensembl
ENSRNOG00000020247
resolver
ensp
ENSRNOP00000027421
resolver
ensp
ENSRNOP00000082060
resolver
enst
ENSRNOT00000027421
resolver
enst
ENSRNOT00000105446
resolver
genesymbol
Cnih2
resolver
uniprot
A0A8I5ZV84
resolver
uniprot_entry
A0A8I5ZV84_RAT
resolver
uniprot_entry
CNIH2_RAT
resolver
amino_acid_sequence
MAFTFAAFCYMLTLVLCASLIFFVIWHIIAFDELRTDFKNPIDQGNPARARERLKNIERICCLLRKLVVPEYSIHGLFCLMFLCAAEWVTLGLNIPLLFYHLWRYFHRPADGSEVMYDAVSIMNADILNYCQKESWCKLAFYLLSFFYYLYSMVYTLVSF
uniprot
proteins
function
FUNCTION: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. {ECO:0000269|PubMed:19265014, ECO:0000269|PubMed:20805473}.
uniprot
proteins
mass_dalton
18931
uniprot
proteins
protein_family
Cornichon family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19265014
uniprot
proteins
pubmed
20805473
uniprot
proteins
sequence_length
160
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Postsynaptic cell membrane {ECO:0000269|PubMed:19265014}; Multi-pass membrane protein {ECO:0000269|PubMed:19265014}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Postsynaptic density {ECO:0000250}. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 73..93; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 139..159; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins