Best3
entrez
382427
canonical
uniprot
Q6H1V1
canonical
ensembl
ENSMUSG00000020169
resolver
ensp
ENSMUSP00000020378
resolver
ensp
ENSMUSP00000291465
resolver
genesymbol
Best3
resolver
genesymbol_syn
Vmd2l3
resolver
uniprot_entry
BEST3_MOUSE
resolver
amino_acid_sequence
MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGAQKRYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMLLISSSVHGSDQHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTADERKLFDHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYVGHDLDLYVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTIQMGLSGSNFPAEDWLWNYEKHGNRHSVMRRVKRFLSTHEHPGSPRRRRSFGRQASDSSMFLPPSPARDLLDVPSRNPHRGSPTRKQSRSQEGSPKLHSSMGELSTIRETSRTSTLQSLSPQSSVRSSPTKMPQVPEVLITAAEAPAFSADSHQHDSTTSILSLEFTGVQPSGTEQQVEPSGTPPGDPNPQTTSASTERDLFKFEEDLEDDRFPKRWSLPEFLESRHTSLGNLGPDPVSPRDALLLPDTETPSETNGIHPGAGSALAPDILYLMESLDKETDILEFNNEHTGESPKGTPQRPRTWF
uniprot
proteins
function
FUNCTION: [Isoform 1]: Ligand-gated anion channel that allows the movement of chloride monoatomic anions across cell membranes when activated by calcium (Ca2+). {ECO:0000269|PubMed:18414923}.; FUNCTION: [Isoform 2]: Does not function as calcium-gated chloride channel. {ECO:0000269|PubMed:18414923}.
uniprot
proteins
mass_dalton
76431
uniprot
proteins
protein_family
Anion channel-forming bestrophin (TC 1.A.46) family
uniprot
proteins
protein_family
Calcium-sensitive chloride channel subfamily
uniprot
proteins
pubmed
15218265
uniprot
proteins
pubmed
18414923
uniprot
proteins
sequence_length
669
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane {ECO:0000269|PubMed:18414923}. Note=Localized also in punctate structures in the cytosolic compartment. {ECO:0000269|PubMed:18414923}.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane {ECO:0000269|PubMed:18414923}. Note=Localized also in punctate structures in the cytosolic compartment. {ECO:0000269|PubMed:18414923}.
uniprot
proteins
transmembrane_region
TRANSMEM 32..51; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O76090"; TRANSMEM 61..82; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O76090"; TRANSMEM 238..255; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O76090"; TRANSMEM 275..288; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O76090
uniprot
proteins