Slc25a3
entrez
18674
canonical
uniprot
Q8VEM8
canonical
ensembl
ENSMUSG00000061904
resolver
ensp
ENSMUSP00000075987
resolver
ensp
ENSMUSP00000127098
resolver
ensp
ENSMUSP00000132480
resolver
enst
ENSMUST00000076694
resolver
enst
ENSMUST00000164505
resolver
enst
ENSMUST00000170810
resolver
genesymbol
Slc25a3
resolver
uniprot
G5E902
resolver
uniprot
Q542V7
resolver
uniprot_entry
G5E902_MOUSE
resolver
uniprot_entry
S25A3_MOUSE
resolver
uniprot_sec
Q542V7
resolver
amino_acid_sequence
MFSSVAHLARANPFNAPHLQLVHDGLSGPRSPPAPPRRSRHLAAAAVEEYSCEFGSMKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVFKALYSNILGEENTYLWRTSLYLASSASAEFFADIALAPMEAAKVRIQTQPGYANTLREAVPKMYKEEGLNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSTASQVLQRLGFRGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTE
uniprot
proteins
function
FUNCTION: Inorganic ion transporter that transports phosphate or copper ions across the mitochondrial inner membrane into the matrix compartment (By similarity). Mediates proton-coupled symport of phosphate ions necessary for mitochondrial oxidative phosphorylation of ADP to ATP (By similarity). Transports copper ions probably in the form of anionic copper(I) complexes to maintain mitochondrial matrix copper pool and to supply copper for cytochrome C oxidase complex assembly (PubMed:29237729). May also play a role in regulation of the mitochondrial permeability transition pore (mPTP) (By similarity). {ECO:0000250|UniProtKB:P12234, ECO:0000250|UniProtKB:P16036, ECO:0000250|UniProtKB:Q00325, ECO:0000269|PubMed:29237729}.
uniprot
proteins
mass_dalton
39632
uniprot
proteins
protein_family
Mitochondrial carrier (TC 2.A.29) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
29237729
uniprot
proteins
sequence_length
357
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250|UniProtKB:P12234}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P12234}.
uniprot
proteins
transmembrane_region
TRANSMEM 59..81; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 117..136; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 157..178; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 214..233; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 257..279; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 310..328; /note="Helical; Name=6"; /evidence="ECO:0000255
uniprot
proteins