Cd200r1
entrez
57781
canonical
uniprot
Q9ES57
canonical
ensembl
ENSMUSG00000022667
resolver
ensp
ENSMUSP00000053822
resolver
enst
ENSMUST00000057488
resolver
genesymbol
Cd200r1
resolver
genesymbol_syn
Mox2r
resolver
genesymbol_syn
Ox2r
resolver
uniprot_entry
MO2R1_MOUSE
resolver
amino_acid_sequence
MFCFWRTSALAVLLIWGVFVAGSSCTDKNQTTQNNSSSPLTQVNTTVSVQIGTKALLCCFSIPLTKAVLITWIIKLRGLPSCTIAYKVDTKTNETSCLGRNITWASTPDHSPELQISAVTLQHEGTYTCETVTPEGNFEKNYDLQVLVPPEVTYFPEKNRSAVCEAMAGKPAAQISWSPDGDCVTTSESHSNGTVTVRSTCHWEQNNVSDVSCIVSHLTGNQSLSIELSRGGNQSLRPYIPYIIPSIIILIIIGCICLLKISGFRKCKLPKLEATSAIEEDEMQPYASYTEKSNPLYDTVTKVEAFPVSQGEVNGTDCLTLSAIGI
uniprot
proteins
function
FUNCTION: Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. {ECO:0000269|PubMed:12960329, ECO:0000269|PubMed:15187158}.
uniprot
proteins
mass_dalton
35505
uniprot
proteins
mutagenesis
MUTAGEN 138; /note="F->L: 7-fold reduction in binding to CD200."; /evidence="ECO:0000269|PubMed:23602662
uniprot
proteins
protein_family
CD200R family
uniprot
proteins
pubmed
10981966
uniprot
proteins
pubmed
12960329
uniprot
proteins
pubmed
15187158
uniprot
proteins
pubmed
15274657
uniprot
proteins
pubmed
15471863
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
23602662
uniprot
proteins
pubmed
24388216
uniprot
proteins
sequence_length
326
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 239..259; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins