POLE3
entrez
54107
canonical
uniprot
Q9NRF9
canonical
ensembl
ENSG00000148229
resolver
ensp
ENSP00000363284
resolver
ensp
ENSP00000363286
resolver
ensp
ENSP00000610641
resolver
enst
ENST00000374169
resolver
enst
ENST00000374171
resolver
enst
ENST00000940582
resolver
genesymbol
POLE3
resolver
genesymbol_syn
CHRAC17
resolver
hgnc
HGNC:13546
resolver
uniprot
Q5W0U1
resolver
uniprot
Q8N758
resolver
uniprot
Q8NCE5
resolver
uniprot
Q9NR32
resolver
uniprot_entry
DPOE3_HUMAN
resolver
uniprot_sec
Q5W0U1
resolver
uniprot_sec
Q8N758
resolver
uniprot_sec
Q8NCE5
resolver
uniprot_sec
Q9NR32
resolver
amino_acid_sequence
MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN
uniprot
proteins
function
FUNCTION: Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity). Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 (PubMed:10801849). Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (PubMed:14759371). {ECO:0000250|UniProtKB:Q04603, ECO:0000269|PubMed:10801849, ECO:0000269|PubMed:14759371}.
uniprot
proteins
mass_dalton
16860
uniprot
proteins
pubmed
10801849
uniprot
proteins
pubmed
10880450
uniprot
proteins
pubmed
12434153
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14759371
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
sequence_length
147
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins