Ephx3
entrez
71932
canonical
uniprot
Q3V1F8
canonical
ensembl
ENSMUSG00000037577
resolver
ensp
ENSMUSP00000085013
resolver
ensp
ENSMUSP00000124600
resolver
enst
ENSMUST00000087721
resolver
enst
ENSMUST00000162117
resolver
genesymbol
Ephx3
resolver
genesymbol_syn
Abhd9
resolver
uniprot
A0A0R4J127
resolver
uniprot
G3XA19
resolver
uniprot_entry
A0A0R4J127_MOUSE
resolver
uniprot_entry
EPHX3_MOUSE
resolver
uniprot_entry
G3XA19_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by 1-(1-acetylpiperidin-4-yl)-3-(4-(trifl uoromethoxy)phenyl)urea (TPAU), 1-cyclohexyl-3-dodecylurea (CDU), 12-(3-adamantan-1-yl-ureido)-dodecanoic acid (AUDA), 1-((3S, 5S, 7S)-adamantan-1-yl)-3-(5-(2-(2-ethoxyethoxy) ethoxy)pentyl)urea (AEPU) and to a lesser extent by 8-(3-((3S, 5S, 7S)-adamantan-1-yl)ureido) octanoic acid (AUOA). {ECO:0000250|UniProtKB:Q9H6B9}.
uniprot
proteins
amino_acid_sequence
MPEFVVTALLAPSRLSLKLLRALVMSLVYLAALVAAFVYSCIALTHVMCRPRRGCCGRQRLSPPECLRDPTLGEHCFLTLRVSVPPVKSSGLRLHYVSAGHGNGPLMLFLHGFPENWFSWRYQLREFQSHFHVVAVDMRGYSPSDAPKEVDCYTIDLLLDDIKDTILGLGYSKCILVSHDWGASLAWEFSIYYPSLVERMVVANGPPMSVIQEYSIHHIGQIFRSNYMFLFQLPWLPEKLLSMSDFQILKDTFTHRKNGIPGLTPSELEAFLYHFSQPGCLTGPINYYRNVFRNFPLEPKKLSTPTLLLWGEKDFAFQQGLVEAIGRHFVPGRLESHILPGSGHWIPQSHPQEMHQYMWAFLQDLLG
uniprot
proteins
ec_number
3.3.2.10
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of epoxide-containing fatty acids. Active in vitro against epoxyeicosatrienoic acids (EETs) including 8,9-EET, 9,10-EET, 11,12-EET and 14,15-EET and leukotoxin. {ECO:0000250|UniProtKB:Q9H6B9}.
uniprot
proteins
mass_dalton
41853
uniprot
proteins
protein_family
AB hydrolase superfamily
uniprot
proteins
protein_family
Epoxide hydrolase family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
22798687
uniprot
proteins
pubmed
28384353
uniprot
proteins
sequence_length
367
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Microsome membrane {ECO:0000250|UniProtKB:Q9H6B9}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 22..42; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins