PIK3IP1
entrez
113791
canonical
uniprot
Q96FE7
canonical
ensembl
ENSG00000100100
resolver
ensp
ENSP00000215912
resolver
ensp
ENSP00000415608
resolver
genesymbol
PIK3IP1
resolver
genesymbol_syn
HGFL
resolver
hgnc
HGNC:24942
resolver
uniprot
B4DRR9
resolver
uniprot
D1MEI0
resolver
uniprot
O00318
resolver
uniprot
Q49A94
resolver
uniprot
Q86YW2
resolver
uniprot
Q8NCJ9
resolver
uniprot_entry
P3IP1_HUMAN
resolver
uniprot_sec
B4DRR9
resolver
uniprot_sec
D1MEI0
resolver
uniprot_sec
O00318
resolver
uniprot_sec
Q49A94
resolver
uniprot_sec
Q86YW2
resolver
uniprot_sec
Q8NCJ9
resolver
amino_acid_sequence
MLLAWVQAFLVSNMLLAEAYGSGGCFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGNHSYCRNPDEDPRGPWCYVSGEAGVPEKRPCEDLRCPETTSQALPAFTTEIQEASEGPGADEVQVFAPANALPARSEAAAVQPVIGISQRVRMNSKEKKDLGTLGYVLGITMMVIIIAIGAGIILGYSYKRGKDLKEQHDQKVCEREMQRITLPLSAFTNPTCEIVDEKTVVVHTSQTPVDPQEGTTPLMGQAGTPGA
uniprot
proteins
function
FUNCTION: Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity. {ECO:0000250|UniProtKB:Q7TMJ8}.
uniprot
proteins
mass_dalton
28248
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan heterogeneity at Asn-66: dHex1Hex5HexNAc4 (major) and dHex1Hex6HexNAc5 (minor). {ECO:0000269|PubMed:22171320}.
uniprot
proteins
pubmed
10591208
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15461802
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19088825
uniprot
proteins
pubmed
22171320
uniprot
proteins
sequence_length
263
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19088825}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 169..189; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins