Tbc1d2
entrez
313234
canonical
uniprot
B5DFA1
canonical
ensembl
ENSRNOG00000023348
resolver
ensp
ENSRNOP00000011714
resolver
genesymbol
Tbc1d2
resolver
genesymbol_syn
Tbc1d2a
resolver
uniprot_entry
TBD2A_RAT
resolver
amino_acid_sequence
MEDTPERTPSSESIQPPGLAREPEVTSPGDSEGCARPLDPAPKKLCGYLSKFGGKGPIKGWKCRWFFYDERKCHLYYSRTAQDANPLDSIDLSSATFDCKADAEEEGTFEIKTPSRVITLKAATRQVMLYWLQQLQMKRWEFHNSPPALPATPAAALTENGPTLHLKLEQEEAELEEFLCPVKTPPGLVGTAAALQPVPAMPSALQNISLKHLGTEIQNTMYNIRGNKQAQATAHGPPVEESSQSAEPQRGEQPLISDPSIPEKEPEDPPKSAPRSCVPSGPMQKPKRQSNTFPFFSDGLARSRTAQEKVVALEQQVLMLTKELKSQKELVIILHKALEAAQQEKRASSAYLAATEDRDRLELVRHKVRQIAELNQRVEALEQDRERLVHEAGLREQQVQALQQHVQLLMDKNQAKQQVICKLSQKLTEDLAQPQPADATNGDFLSQQERLEHLKDDMEAYRTQNRFLNSEIHQVTKIWRKVAEKEKALLTKCAYLQARNCQVESKYLAGLRRLQEAAGAEPGDFPELLQQLVQEALQWEAGEASDSVGLSPVSEYDDYGFLTVPDYEVEDLKLLAKIQALEVRSHHLLALEAVERPLRDRWATLTELMPSAELKQLLRAGVPREHRPRVWRWLVHRRVQHLHSSGCYQELLARGRACEHPAARQIELDLNRTFPTNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEDEESAFWCLVAIVETILPAEYYSKTLTASQVDQRVLQDLLSEKLPRLTAHLGQRHVDLSLITFNWFLVIFADSLISDILLRVWDAFLYEGTKVVFRYALAIFKYNEEAILRLQDSLEIYQYLRFFTKTICDSRKLTSIAFNDMNPFPMKQLRQLRAAHRERLEAELRELELLKAEYLERRASRGRAVPEGCVSEDEGEGDS
uniprot
proteins
function
FUNCTION: Acts as a GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
104975
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
924
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction {ECO:0000250}.
uniprot
proteins