Sox13
entrez
20668
canonical
uniprot
Q04891
canonical
ensembl
ENSMUSG00000070643
resolver
ensp
ENSMUSP00000092130
resolver
ensp
ENSMUSP00000119729
resolver
ensp
ENSMUSP00000291619
resolver
ensp
ENSMUSP00000291620
resolver
ensp
ENSMUSP00000291621
resolver
enst
ENSMUST00000094551
resolver
enst
ENSMUST00000153799
resolver
genesymbol
Sox13
resolver
genesymbol_syn
Sox-13
resolver
uniprot
Q922L3
resolver
uniprot_entry
SOX13_MOUSE
resolver
uniprot_sec
Q922L3
resolver
amino_acid_sequence
MSMQSPVSVQLAPDSASTMVNCTIKSEEKKEPCHEAPQGAAPAVETQPGDPALASQDATNAKAPPQDCASPESSGSPEPKRPAASEAASGSQERLDFNRNLQEVVPAIEKLLSSDWKERFLGRSNVEAKDVKGTQESLAEKELQLLVMIHQLSALRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRSGVAAHHPLQEPPQPLNLTAKPKVPELPNTSSSPSLKMNSCGPRPASHGAPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALENSPNTPFRKDLISLDSSPAKERLEESCVHPLEEAMLSCDMDGSRHFSESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCVVEGRRLRVGEYKALMRTRRQGARQSYTIPPQAGQAQVSSDILFPRAAGLPLARPLVEHYDPQGLDPNMPVIINTCSLREEGEGTDDRHSVADGEMYRYSEDEDSEGDEKSDEELVVLTD
uniprot
proteins
function
FUNCTION: Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3' (PubMed:9421502, PubMed:9524265). Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube (PubMed:26525805). Binds to the gene promoter of MBP and acts as a transcriptional repressor (PubMed:26525805). Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells (PubMed:17218525, PubMed:23562159, PubMed:30413363). Required for the differentiation of Vgamma2-positive gamma-delta T-cells, a subset of IL17A expressing gamma-delta T-cells (PubMed:23562159). Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells (PubMed:23562159). Promotes brown adipocyte differentiation (PubMed:27923061). Inhibitor of WNT signaling (By similarity). {ECO:0000250|UniProtKB:Q9UN79, ECO:0000269|PubMed:17218525, ECO:0000269|PubMed:23562159, ECO:0000269|PubMed:26525805, ECO:0000269|PubMed:27923061, ECO:0000269|PubMed:30413363, ECO:0000269|PubMed:9421502, ECO:0000269|PubMed:9524265}.
uniprot
proteins
mass_dalton
68168
uniprot
proteins
pubmed
10871192
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16835393
uniprot
proteins
pubmed
17218525
uniprot
proteins
pubmed
20028982
uniprot
proteins
pubmed
23562159
uniprot
proteins
pubmed
26525805
uniprot
proteins
pubmed
27923061
uniprot
proteins
pubmed
30413363
uniprot
proteins
pubmed
30638933
uniprot
proteins
pubmed
8441686
uniprot
proteins
pubmed
9421502
uniprot
proteins
pubmed
9524265
uniprot
proteins
sequence_length
613
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:10871192, ECO:0000269|PubMed:16835393, ECO:0000269|PubMed:26525805, ECO:0000269|PubMed:9421502}. Cytoplasm {ECO:0000269|PubMed:10871192}.
uniprot
proteins