Gramd4
entrez
223752
canonical
uniprot
Q8CB44
canonical
ensembl
ENSMUSG00000035900
resolver
ensp
ENSMUSP00000086321
resolver
ensp
ENSMUSP00000120796
resolver
enst
ENSMUST00000088931
resolver
enst
ENSMUST00000138134
resolver
genesymbol
Gramd4
resolver
genesymbol_syn
BC021523
resolver
genesymbol_syn
Dip
resolver
genesymbol_syn
Kiaa0767
resolver
uniprot
B2RTC1
resolver
uniprot
D3YUE7
resolver
uniprot
Q5U4C7
resolver
uniprot
Q6ZQ52
resolver
uniprot
Q8VDL6
resolver
uniprot_entry
D3YUE7_MOUSE
resolver
uniprot_entry
GRAM4_MOUSE
resolver
uniprot_entry
Q5U4C7_MOUSE
resolver
uniprot_sec
B2RTC1
resolver
uniprot_sec
Q6ZQ52
resolver
uniprot_sec
Q8VDL6
resolver
amino_acid_sequence
MGIASHSAFRERESSPTGASLDASPRPWDKGLSGREPPRHVQVRPRSAVLNMLRRLDRIRFRGHKREDLLDLAESPNASDTECGDEIPLKTPRPSPRDSEELRDPAGPGTLIMAAGVQDFNRTEFDRLNEIKGHLEIALLEKHFLQEELRKLREETNSEMLRQELDRERQRRIELEQKMQEVLKARSEEQPAQPQQPPKGQSQASNGTGTERRSQGLASRVQKWFYERFGEYIEDFRFQPEENTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWYSIYTSAIAFTVYMNAVWHGWAIPMFLFLAILRLSLNYLIARGWRIQWSIVPEVSEAVEPAKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPETTQKLYVALWAAFLASCFFPYRLVGLAVGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWRSLPTDPQLKERAGATVSRRLQTASSRSYVSSAPAGLSKDEDAGRFHSTKKGNFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSSKRNKVIKLMDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETIFSQYVKITSAAASGGDS
uniprot
proteins
function
FUNCTION: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (By similarity). Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (PubMed:25917084). {ECO:0000250|UniProtKB:Q6IC98, ECO:0000269|PubMed:25917084}.
uniprot
proteins
mass_dalton
72264
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25917084
uniprot
proteins
sequence_length
633
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000250|UniProtKB:Q6IC98}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:25917084}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with COX4I1. {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 295..315; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 389..409; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 411..431; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins