E2F5
entrez
1875
canonical
uniprot
Q15329
canonical
ensembl
ENSG00000133740
resolver
ensp
ENSP00000398124
resolver
ensp
ENSP00000414312
resolver
ensp
ENSP00000429120
resolver
genesymbol
E2F5
resolver
hgnc
HGNC:3119
resolver
uniprot
E9PBN9
resolver
uniprot
Q16601
resolver
uniprot
Q92756
resolver
uniprot_entry
E2F5_HUMAN
resolver
uniprot_sec
E9PBN9
resolver
uniprot_sec
Q16601
resolver
uniprot_sec
Q92756
resolver
amino_acid_sequence
MAAAEPASSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFPVPPPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFDVQILNY
uniprot
proteins
function
FUNCTION: Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis. {ECO:0000250|UniProtKB:Q6DE14}.
uniprot
proteins
mass_dalton
37610
uniprot
proteins
protein_family
E2F/DP family
uniprot
proteins
pubmed
16360038
uniprot
proteins
pubmed
16421571
uniprot
proteins
pubmed
17531812
uniprot
proteins
pubmed
7760804
uniprot
proteins
pubmed
7892279
uniprot
proteins
pubmed
8589754
uniprot
proteins
pubmed
9464260
uniprot
proteins
sequence_length
346
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins