Smg9
entrez
365215
canonical
uniprot
Q5PQS6
canonical
ensembl
ENSRNOG00000019596
resolver
ensp
ENSRNOP00000026669
resolver
ensp
ENSRNOP00000099692
resolver
genesymbol
Smg9
resolver
uniprot_entry
SMG9_RAT
resolver
amino_acid_sequence
MSESGHSQPGLYGIERRRRWKEPGSSGPQNLSGPGGRERDYIAPWERERRDGSEDPSTNVMQKTPIILSKPPAERSKQPPPSTAPAAPPAPAPLEKPIVLMKPREEGKGPVAATGASTPEGTAPPPPTAPAPPKGEKEGQRPTQPVYQIQNRGMGTAAPTAMDPVVGQAKLLPPERMKHSIKLVDDQMNWCDSAIEYLLDQTDVLVVGVLGLQGTGKSMVMSLLSANTPEEDQRAYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSAAGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHLMIDQLMAHSHLRYKGTLSMLQCNIFPGLPPDFLDAEVNLFLVPFMDSEAENENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMSMARPQLSHTILTEKNWFHYAARIWDGVKKSSALAEYSRLLA
uniprot
proteins
function
FUNCTION: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (By similarity). Plays a role in brain, heart, and eye development. {ECO:0000250|UniProtKB:Q9DB90, ECO:0000250|UniProtKB:Q9H0W8}.
uniprot
proteins
mass_dalton
57633
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by SMG1. {ECO:0000250|UniProtKB:Q9H0W8}.
uniprot
proteins
protein_family
SMG9 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
520
uniprot
proteins