Tmem86b
entrez
690610
canonical
uniprot
B0BNF0
canonical
ensembl
ENSRNOG00000087324
resolver
ensembl
ENSRNOG00055010141
resolver
ensembl
ENSRNOG00055014538
resolver
ensembl
ENSRNOG00065032420
resolver
ensp
ENSRNOP00000105181
resolver
ensp
ENSRNOP00055013761
resolver
ensp
ENSRNOP00055020367
resolver
ensp
ENSRNOP00065045966
resolver
enst
ENSRNOT00000171887
resolver
enst
ENSRNOT00055017109
resolver
enst
ENSRNOT00055024929
resolver
enst
ENSRNOT00065055803
resolver
genesymbol
Tmem86b
resolver
uniprot
A0ABK0LUH4
resolver
uniprot_entry
A0ABK0LUH4_RAT
resolver
uniprot_entry
TM86B_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Competitively inhibited by lysophosphatidic acid. {ECO:0000250|UniProtKB:Q8N661}.
uniprot
proteins
amino_acid_sequence
MPCCDPYPWIGLNVGRLSSFPLLKYPQVRRWLAPFIVACSLYFLLWIPEDQPSWVSALVKCQPILCLVLFLWAVAPGGSYTWLLQGALTCSAVGDACLIWPEAFFYGMAVFSVAHLLYLWAFGLSPLQPGLLLCTTLASLTYYSFLLLHLEPNMVLPVAAYGLILNTMLWRGLVLGRSAGWGAVLFIFSDGVLAWDTFVYTLPFARLVTMSTYYAAQLLLTLSALRSPGLKTH
uniprot
proteins
ec_number
3.3.2.2
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of the vinyl ether bond of choline or ethanolamine lysoplasmalogens, forming fatty aldehyde and glycerophosphocholine or glycerophosphoethanolamine, respectively and is specific for the sn-2-deacylated (lyso) form of plasmalogen. {ECO:0000269|PubMed:21515882}.
uniprot
proteins
mass_dalton
25912
uniprot
proteins
protein_family
TMEM86 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21515882
uniprot
proteins
sequence_length
233
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D8N3}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:Q8N661}.
uniprot
proteins
transmembrane_region
TRANSMEM 31..47; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 54..75; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 82..100; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 107..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 131..147; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 154..170; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 179..195; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 207..225; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins