Slc30a6
entrez
210148
canonical
uniprot
Q8BJM5
canonical
ensembl
ENSMUSG00000024069
resolver
ensp
ENSMUSP00000024870
resolver
ensp
ENSMUSP00000136503
resolver
ensp
ENSMUSP00000213345
resolver
ensp
ENSMUSP00000213347
resolver
enst
ENSMUST00000024870
resolver
enst
ENSMUST00000179074
resolver
genesymbol
Slc30a6
resolver
genesymbol_syn
Znt6
resolver
uniprot
J3QMX8
resolver
uniprot
Q3UB35
resolver
uniprot
Q6NVE0
resolver
uniprot
Q8K4H6
resolver
uniprot
Q8R4Z2
resolver
uniprot
Q99JQ3
resolver
uniprot_entry
J3QMX8_MOUSE
resolver
uniprot_entry
ZNT6_MOUSE
resolver
uniprot_sec
Q3UB35
resolver
uniprot_sec
Q6NVE0
resolver
uniprot_sec
Q8K4H6
resolver
uniprot_sec
Q8R4Z2
resolver
uniprot_sec
Q99JQ3
resolver
amino_acid_sequence
MGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILLFGAINVLCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLITCLISYWVMMRKPSPVYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGLIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVSNRLCTLVSTLTVQIFKDDWIRPALSSGPVAPNVLNFSDHHVIPMPLLKNVDERTPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYSLGLNRGHTPYSSVFSQGLAFPGVGAGQGLRPTFPHIPSRYGINRMGQPRP
uniprot
proteins
function
FUNCTION: Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (Probable). As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (By similarity). {ECO:0000250|UniProtKB:Q6NXT4, ECO:0000305|PubMed:11997387}.
uniprot
proteins
mass_dalton
51027
uniprot
proteins
protein_family
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
uniprot
proteins
protein_family
SLC30A subfamily
uniprot
proteins
pubmed
11997387
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17101726
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
460
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:11997387}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:17101726}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 34..54; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 65..85; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 99..119; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 135..155; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 201..221; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 224..244; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins