RAB19
entrez
401409
canonical
uniprot
A4D1S5
canonical
ensembl
ENSG00000146955
resolver
ensp
ENSP00000440167
resolver
ensp
ENSP00000567854
resolver
ensp
ENSP00000567855
resolver
ensp
ENSP00000594087
resolver
ensp
ENSP00000594088
resolver
genesymbol
RAB19
resolver
genesymbol_syn
RAB19B
resolver
hgnc
HGNC:19982
resolver
uniprot
A4D1S6
resolver
uniprot
B2RTS6
resolver
uniprot
B5MDR2
resolver
uniprot
Q9UL27
resolver
uniprot_entry
RAB19_HUMAN
resolver
uniprot_sec
A4D1S6
resolver
uniprot_sec
B2RTS6
resolver
uniprot_sec
B5MDR2
resolver
uniprot_sec
Q9UL27
resolver
activity_regulation
ACTIVITY REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. Regulated by GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity. Inhibited by GDP dissociation inhibitors (GDIs). {ECO:0000305}.
uniprot
proteins
amino_acid_sequence
MHFSSSARAADENFDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIGNKCDLWEKRHVLFEDACTLAEKYGLLAVLETSAKESKNIEEVFVLMAKELIARNSLHLYGESALNGLPLDSSPVLMAQGPSEKTHCTC
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. {ECO:0000250|UniProtKB:Q9H0U4}.
uniprot
proteins
mass_dalton
24400
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
217
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
uniprot
proteins