Nubp2
entrez
26426
canonical
uniprot
Q9R061
canonical
ensembl
ENSMUSG00000039183
resolver
ensp
ENSMUSP00000049319
resolver
ensp
ENSMUSP00000157064
resolver
ensp
ENSMUSP00000157175
resolver
ensp
ENSMUSP00000157378
resolver
ensp
ENSMUSP00000322671
resolver
enst
ENSMUST00000044252
resolver
enst
ENSMUST00000234597
resolver
enst
ENSMUST00000234928
resolver
genesymbol
Nubp2
resolver
uniprot
A0A3Q4EH93
resolver
uniprot_entry
A0A3Q4EH93_MOUSE
resolver
uniprot_entry
NUBP2_MOUSE
resolver
amino_acid_sequence
MEAAAGERAEPGNLAGVRHIILVLSGKGGVGKSTISTELALALRHQGKKVGILDVDLCGPSIPHMLRAQGKAVHQCDNGWVPVFVDQEQSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDEHMATMEALRPYRPLGALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAGVPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRVVHRMSALCS
uniprot
proteins
function
FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure (PubMed:23807208). {ECO:0000255|HAMAP-Rule:MF_03039, ECO:0000269|PubMed:23807208}.
uniprot
proteins
mass_dalton
29518
uniprot
proteins
protein_family
Mrp/NBP35 ATP-binding proteins family
uniprot
proteins
protein_family
NUBP2/CFD1 subfamily
uniprot
proteins
pubmed
10486206
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16638812
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23807208
uniprot
proteins
sequence_length
275
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|HAMAP-Rule:MF_03039, ECO:0000269|PubMed:16638812}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255|HAMAP-Rule:MF_03039, ECO:0000269|PubMed:16638812}. Cytoplasm {ECO:0000269|PubMed:23807208}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:23807208}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23807208}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000269|PubMed:23807208}. Note=Enriched at the centrosomes during mitosis (By similarity). Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis (PubMed:23807208). Localized at centrioles and in the nucleus at interphase (PubMed:23807208). Colocalizes with nubp-1 at prometaphase (PubMed:23807208). {ECO:0000255|HAMAP-Rule:MF_03039, ECO:0000269|PubMed:23807208}.
uniprot
proteins