Gulo
entrez
268756
canonical
uniprot
P58710
canonical
ensembl
ENSMUSG00000034450
resolver
ensp
ENSMUSP00000060912
resolver
enst
ENSMUST00000059970
resolver
genesymbol
Gulo
resolver
uniprot
Q8K152
resolver
uniprot_entry
GGLO_MOUSE
resolver
uniprot_sec
Q8K152
resolver
amino_acid_sequence
MVHGYKGVQFQNWAKTYGCSPEMYYQPTSVGEVREVLALARQQNKKVKVVGGGHSPSDIACTDGFMIHMGKMNRVLQVDKEKKQVTVEAGILLTDLHPQLDKHGLALSNLGAVSDVTVGGVIGSGTHNTGIKHGILATQVVALTLMKADGTVLECSESSNADVFQAARVHLGCLGVILTVTLQCVPQFHLLETSFPSTLKEVLDNLDSHLKKSEYFRFLWFPHSENVSIIYQDHTNKEPSSASNWFWDYAIGFYLLEFLLWTSTYLPRLVGWINRFFFWLLFNCKKESSNLSHKIFSYECRFKQHVQDWAIPREKTKEALLELKAMLEAHPKVVAHYPVEVRFTRGDDILLSPCFQRDSCYMNIIMYRPYGKDVPRLDYWLAYETIMKKFGGRPHWAKAHNCTRKDFEKMYPAFHKFCDIREKLDPTGMFLNSYLEKVFY
uniprot
proteins
ec_number
1.1.3.8
uniprot
proteins
function
FUNCTION: Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate. {ECO:0000269|PubMed:14962674}.
uniprot
proteins
mass_dalton
50478
uniprot
proteins
pathway_participation
PATHWAY: Cofactor biosynthesis; L-ascorbate biosynthesis via UDP-alpha-D-glucuronate pathway; L-ascorbate from UDP-alpha-D-glucuronate: step 4/4.
uniprot
proteins
protein_family
Oxygen-dependent FAD-linked oxidoreductase family
uniprot
proteins
pubmed
14962674
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
440
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Microsome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 251..273; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins