NPFFR2
entrez
10886
canonical
uniprot
Q9Y5X5
canonical
ensembl
ENSG00000056291
resolver
ensp
ENSP00000307822
resolver
ensp
ENSP00000340789
resolver
ensp
ENSP00000351599
resolver
ensp
ENSP00000379321
resolver
enst
ENST00000344413
resolver
genesymbol
NPFFR2
resolver
genesymbol_syn
GPR74
resolver
genesymbol_syn
NPFF2
resolver
genesymbol_syn
NPGPR
resolver
hgnc
HGNC:4525
resolver
uniprot
A0A804CC06
resolver
uniprot
A0PJM9
resolver
uniprot
Q96RV1
resolver
uniprot
Q9NR49
resolver
uniprot_entry
A0A804CC06_HUMAN
resolver
uniprot_entry
A0PJM9_HUMAN
resolver
uniprot_entry
NPFF2_HUMAN
resolver
uniprot_sec
Q96RV1
resolver
uniprot_sec
Q9NR49
resolver
amino_acid_sequence
MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRRLGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
uniprot
proteins
function
FUNCTION: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. {ECO:0000269|PubMed:11024015}.
uniprot
proteins
mass_dalton
60270
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10079187
uniprot
proteins
pubmed
10837915
uniprot
proteins
pubmed
10851242
uniprot
proteins
pubmed
11024015
uniprot
proteins
sequence_length
522
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11024015}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 148..168; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 185..205; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 222..242; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 263..283; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 320..340; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 378..398; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 414..434; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins