Syt6
entrez
60565
canonical
uniprot
Q62746
canonical
ensembl
ENSRNOG00000019163
resolver
ensembl
ENSRNOG00055018902
resolver
ensembl
ENSRNOG00060030707
resolver
ensembl
ENSRNOG00065031251
resolver
ensp
ENSRNOP00000025953
resolver
ensp
ENSRNOP00000081725
resolver
enst
ENSRNOT00000094540
resolver
genesymbol
Syt6
resolver
uniprot
A0A8I5ZT49
resolver
uniprot
Q4KLI6
resolver
uniprot_entry
A0A8I5ZT49_RAT
resolver
uniprot_entry
SYT6_RAT
resolver
uniprot_sec
Q4KLI6
resolver
amino_acid_sequence
MSGVWGAGGPRCQAALAVLASLCRARPPPLGLDVETCQSFELQPPEQSPSAADSGTSVSLLAVVVIVCGVALVAVFFFLFWKLCWMPWRNKEASSPSSANPASEILQSPSSRGNMADKLKDPSALGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTKLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAAEQPTSIGRIKPELYKQKSVDGDEAKSEAAKSCGKINFSLRYDYESETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGISAEGLGRDHWNEMLAYPRKPIAHWHCLAEVKKSFKEGTPRL
uniprot
proteins
function
FUNCTION: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm (By similarity). {ECO:0000250|UniProtKB:Q9R0N8}.
uniprot
proteins
mass_dalton
57179
uniprot
proteins
protein_family
Synaptotagmin family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
7791877
uniprot
proteins
sequence_length
511
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q9R0N8}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9R0N8}.; SUBCELLULAR LOCATION: [Isoform 1]: Membrane {ECO:0000250|UniProtKB:Q9R0N8}; Single-pass membrane protein {ECO:0000250}. Note=Localized predominantly to endoplasmic reticulum (ER) and/or Golgi-like perinuclear compartment (By similarity). {ECO:0000250|UniProtKB:Q9R0N8}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9R0N8}. Cell membrane {ECO:0000250|UniProtKB:Q9R0N8}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9R0N8}.
uniprot
proteins
transmembrane_region
TRANSMEM 60..80; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins