MTA3
entrez
57504
canonical
uniprot
Q9BTC8
canonical
ensembl
ENSG00000057935
resolver
ensp
ENSP00000383973
resolver
ensp
ENSP00000384249
resolver
ensp
ENSP00000385045
resolver
ensp
ENSP00000385823
resolver
ensp
ENSP00000626490
resolver
ensp
ENSP00000661885
resolver
enst
ENST00000405592
resolver
enst
ENST00000406652
resolver
genesymbol
MTA3
resolver
genesymbol_syn
KIAA1266
resolver
hgnc
HGNC:23784
resolver
uniprot
F6RRE2
resolver
uniprot
Q9NSP2
resolver
uniprot
Q9ULF4
resolver
uniprot_entry
F6RRE2_HUMAN
resolver
uniprot_entry
MTA3_HUMAN
resolver
uniprot_sec
Q9NSP2
resolver
uniprot_sec
Q9ULF4
resolver
amino_acid_sequence
MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAVNGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLKMPTQSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKFARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELSGSPLKSKSTRKPLACIIGYLEIHPAKKPNVIRSTPSLQTPTTKRMLTTPNHTSLSILGKRNYSHHNGLDELTCCVSD
uniprot
proteins
function
FUNCTION: Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:12705869, PubMed:16428440, PubMed:28977666). Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels (PubMed:12705869). Contributes to transcriptional repression by BCL6 (PubMed:15454082). {ECO:0000269|PubMed:12705869, ECO:0000269|PubMed:15454082, ECO:0000269|PubMed:16428440, ECO:0000269|PubMed:28977666}.
uniprot
proteins
mass_dalton
67504
uniprot
proteins
protein_family
Metastasis-associated protein family
uniprot
proteins
pubmed
10574462
uniprot
proteins
pubmed
12705869
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15454082
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16428440
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22926524
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
28977666
uniprot
proteins
pubmed
33283408
uniprot
proteins
sequence_length
594
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:12705869, ECO:0000269|PubMed:28977666, ECO:0000269|PubMed:33283408}. Cytoplasm {ECO:0000250|UniProtKB:Q924K8}.
uniprot
proteins