Mn1
entrez
433938
canonical
uniprot
D3YWE6
canonical
ensembl
ENSMUSG00000070576
resolver
ensp
ENSMUSP00000092034
resolver
enst
ENSMUST00000094463
resolver
genesymbol
Mn1
resolver
uniprot_entry
MN1_MOUSE
resolver
amino_acid_sequence
MFGLDQFEPQINSRHAGQGEGNFNEAGLSMNAHFKAPAFHAGPPTGPVDPAISALGEPPILGLNMEPYGFHARSHSELHAGGLQAQPVHGFFGGQQPHHSHPGGHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAESYEHMAESQGPEGFGPQRPGNLPDFHSSGTSGHAVPAPCLPLDQSPNRAASFHGLSASSGSDSHSLEPRRVTNQGAVDSLEYNYPSEPPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRASGMVGLSKMHSQPPQPPPQQQQPQHGVFFERFGGARKMPVGLEPAVGSRHPLMQPPQQAPPPPQQPPPQQQPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGTLDNQLSPSAYPGLPGEFTPPVPDSFSSGPPLQHPGPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGSVGGLAQTNFEREGGSAGAGRLSGFEQQAPHLAQESAWFPGPHPPGDLLPRRMGGAGLPTDCGPHDPALAPPPAPGGSGVLFRGSLQEPLRMPGEGHVPALASPGLQFGGSLAGLGQLQSPGAGVGLPNAPSERRPPPPDFPAPALGGQPGFPFGSGSRQATPHSAPGVNSPPSAGSGSSGAGGGAYPPQPDFQPSQRNSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNEPDSAVAAGNPGSDYFPGGTTPGAPGPGGPSGTSGGGSKASGPPNPPIQGDSTSLSPNYTLESTSGNDGKPVPGGSGRGRGRRKRDSGHVSPGTFFDKYSTAPDSGGAPGVSPGQQQAPGSAAGGSSVNEARGPTPHEKALTSPSWGKGAELLLGDQPDLMASLDSTAKSDGSSPHVGEFASDEVSTSYANEDEVSSSSDNTTALAKASRSPLVTSSPKLPPRGVGAGEHTPKASALGLGILSTSTSTPDSYGGGVGTGHPGTPGLEQVRTPTSSSGAQPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGSKKAECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSTTWYMPPDKALVDGGDEDKTLAPWEKAKSQNPNNKEAHDHPTNKASATQPGSHLQCLTVHCTDGDPKARTSVPTWRSLHSDISNRFGTFVAALT
uniprot
proteins
function
FUNCTION: Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate (PubMed:18948418). Required during later stages of palate development for normal growth and medial fusion of the palatal shelves (PubMed:18948418). Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL (PubMed:19386590). Necessary for normal development of the membranous bones of the skull (PubMed:15870292). May play a role in tumor suppression (By similarity). {ECO:0000250|UniProtKB:Q10571, ECO:0000269|PubMed:15870292, ECO:0000269|PubMed:18948418, ECO:0000269|PubMed:19386590}.
uniprot
proteins
mass_dalton
134072
uniprot
proteins
pubmed
15870292
uniprot
proteins
pubmed
18948418
uniprot
proteins
pubmed
19386590
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
1297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q10571}.
uniprot
proteins