Myo1e
entrez
25484
canonical
uniprot
Q63356
canonical
ensembl
ENSRNOG00000061928
resolver
ensembl
ENSRNOG00055007084
resolver
ensembl
ENSRNOG00060017424
resolver
ensembl
ENSRNOG00065016265
resolver
ensp
ENSRNOP00000074970
resolver
ensp
ENSRNOP00000101453
resolver
ensp
ENSRNOP00055009296
resolver
ensp
ENSRNOP00060024317
resolver
ensp
ENSRNOP00065021323
resolver
enst
ENSRNOT00000171134
resolver
enst
ENSRNOT00055011767
resolver
enst
ENSRNOT00060030120
resolver
enst
ENSRNOT00065027124
resolver
genesymbol
Myo1e
resolver
genesymbol_syn
Myr3
resolver
uniprot_entry
MYO1E_RAT
resolver
amino_acid_sequence
MGSKGAYRYHWQSHNVKHSGVDDMVLLSKITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGITSMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNINFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPVWRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVARKKYVQMREDASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADIVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEVERILSVSLSTMQDDIFILHEQEYDSLLESVFKTEFLSLLTKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFYQGFGDLAILKPSNKVLQVSIGPGLPKNARPTRRNTVSSRGYSGGTNNNYPMRAAPAPPGCHRNGLTRNQFVHPPRASGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDVIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI
uniprot
proteins
function
FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Involved in clathrin-mediated endocytosis and intracellular movement of clathrin-coated ve (By similarity)sicles. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function (By similarity). In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14 (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
126827
uniprot
proteins
protein_family
Myosin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
12486594
uniprot
proteins
pubmed
7730414
uniprot
proteins
sequence_length
1107
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:7730414}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:7730414}. Cytoplasmic vesicle {ECO:0000305|PubMed:7730414}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. Cell junction {ECO:0000269|PubMed:7730414}. Note=In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles (By similarity). Detected in cytoplasmic punctae. Colocalizes with F-actin. {ECO:0000250}.
uniprot
proteins