Q6ZUV0
uniprot
Q6ZUV0
canonical
amino_acid_sequence
MIKEAGAIISTRHCNPQNGDRCVAALARVECTHFLWPMCIGEVAHVSAEITYTSKHSVEVQVNMMSENILTGAKKLTNKATLWYAPLSLTNVDKVLEEPPVVYFRQEQEEEGQKRYKTQKLERMETNWRNGDIVQPVLNPEPNTVSYSQSSLIHLVGPSDCTLHSFVHEGVTMKVMDEVAGILAARHCKTNLVTASMEAINFDNKIRKGCIKTISGRMTFTSNKSVEIEVLVDADCVVDSSQKRYRAASVFT
uniprot
proteins
disease_involvement
DISEASE: Note=A functional variant in the transcriptional regulatory region of in ACOT7L cosegregates with disease phenotype in family affected by nasopharyngeal carcinoma. The variant creates an AP1-binding site that significantly enhances binding of AP1 to the promoter, resulting in up-regulation.
uniprot
proteins
function
FUNCTION: Acyl-CoA thioesterase-like protein that may catalyze the hydrolysis of acyl-CoA thioesters to free fatty acids and coenzyme A. Probably lacks enzymatic activity due to the absence of the N-terminal domain containing residue essential for catalysis. {ECO:0000250|UniProtKB:Q91V12}.
uniprot
proteins
mass_dalton
28164
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
16423998
uniprot
proteins
sequence_length
252
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins