Psmb10
entrez
19171
canonical
uniprot
O35955
canonical
ensembl
ENSMUSG00000031897
resolver
ensp
ENSMUSP00000034369
resolver
enst
ENSMUST00000034369
resolver
genesymbol
Psmb10
resolver
genesymbol_syn
Lmp10
resolver
genesymbol_syn
Mecl1
resolver
uniprot
O08687
resolver
uniprot
Q99KC5
resolver
uniprot_entry
PSB10_MOUSE
resolver
uniprot_sec
O08687
resolver
uniprot_sec
Q99KC5
resolver
amino_acid_sequence
MLKQAVEPTGGFSFENCQRNASLEHVLPGLRVPHARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQLYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACVITAGGAKLQRALSTPTEPVQRAGRYRFAPGTTPVLTREVRPLTLELLEETVQAMEVE
uniprot
proteins
ec_number
3.4.25.1
uniprot
proteins
function
FUNCTION: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Plays a role in determining the T-cell repertoire for an antiviral T-cell response. {ECO:0000269|PubMed:22341445}.
uniprot
proteins
mass_dalton
29063
uniprot
proteins
mutagenesis
MUTAGEN 40; /note="T->A: Prevents the correct removal of the propeptide."; /evidence="ECO:0000269|PubMed:10413086
uniprot
proteins
post_translational_modification
PTM: Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity. {ECO:0000305|PubMed:10413086}.
uniprot
proteins
protein_family
Peptidase T1B family
uniprot
proteins
pubmed
10413086
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15907481
uniprot
proteins
pubmed
16709825
uniprot
proteins
pubmed
16857966
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22341445
uniprot
proteins
pubmed
23706739
uniprot
proteins
pubmed
9300697
uniprot
proteins
pubmed
9367687
uniprot
proteins
sequence_length
273
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus {ECO:0000250}.
uniprot
proteins