ARL8A
entrez
127829
canonical
uniprot
Q96BM9
canonical
ensembl
ENSG00000143862
resolver
ensp
ENSP00000272217
resolver
ensp
ENSP00000485023
resolver
enst
ENST00000272217
resolver
enst
ENST00000614750
resolver
genesymbol
ARL8A
resolver
genesymbol_syn
ARL10B
resolver
genesymbol_syn
GIE2
resolver
hgnc
HGNC:25192
resolver
uniprot
A0A087X2J2
resolver
uniprot
B3KXD0
resolver
uniprot_entry
A0A087X2J2_HUMAN
resolver
uniprot_entry
ARL8A_HUMAN
resolver
uniprot_sec
B3KXD0
resolver
amino_acid_sequence
MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQLQGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS
uniprot
proteins
function
FUNCTION: Plays a role in lysosome motility (By similarity). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (By similarity). {ECO:0000250|UniProtKB:Q9CQW2, ECO:0000250|UniProtKB:Q9NVJ2}.
uniprot
proteins
mass_dalton
21416
uniprot
proteins
protein_family
Arf family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15331635
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16537643
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17897319
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28325809
uniprot
proteins
pubmed
35314674
uniprot
proteins
sequence_length
186
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Late endosome membrane {ECO:0000250|UniProtKB:Q9NVJ2}. Lysosome membrane {ECO:0000250|UniProtKB:Q9CQW2}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9NVJ2}. Cell projection, axon {ECO:0000250|UniProtKB:Q9CQW2}. Synapse {ECO:0000250|UniProtKB:Q9CQW2}. Note=Localizes with microtubules at the spindle mid-zone during mitosis. {ECO:0000250|UniProtKB:Q9NVJ2}.
uniprot
proteins