TNFRSF12A
entrez
51330
canonical
uniprot
Q9NP84
canonical
ensembl
ENSG00000006327
resolver
ensp
ENSP00000326737
resolver
genesymbol
TNFRSF12A
resolver
genesymbol_syn
FN14
resolver
hgnc
HGNC:18152
resolver
uniprot
D3DUA6
resolver
uniprot
Q9HCS0
resolver
uniprot_entry
TNR12_HUMAN
resolver
uniprot_sec
D3DUA6
resolver
uniprot_sec
Q9HCS0
resolver
amino_acid_sequence
MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAAPPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGEGCPAVALIQ
uniprot
proteins
function
FUNCTION: Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. {ECO:0000269|PubMed:11728344}.
uniprot
proteins
mass_dalton
13911
uniprot
proteins
pubmed
10751351
uniprot
proteins
pubmed
11728344
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19241374
uniprot
proteins
sequence_length
129
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 81..101; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins