PGLYRP3
entrez
114771
canonical
uniprot
Q96LB9
canonical
ensembl
ENSG00000159527
resolver
ensp
ENSP00000290722
resolver
ensp
ENSP00000507327
resolver
enst
ENST00000290722
resolver
enst
ENST00000683862
resolver
genesymbol
PGLYRP3
resolver
genesymbol_syn
PGRPIA
resolver
hgnc
HGNC:30014
resolver
uniprot
A1A4U8
resolver
uniprot
Q5SY65
resolver
uniprot_entry
PGRP3_HUMAN
resolver
uniprot_sec
A1A4U8
resolver
uniprot_sec
Q5SY65
resolver
amino_acid_sequence
MGTLPWLLAFFILGLQAWDTPTIVSRKEWGARPLACRALLTLPVAYIITDQLPGMQCQQQSVCSQMLRGLQSHSVYTIGWCDVAYNFLVGDDGRVYEGVGWNIQGLHTQGYNNISLGIAFFGNKIGSSPSPAALSAAEGLISYAIQKGHLSPRYIQPLLLKEETCLDPQHPVMPRKVCPNIIKRSAWEARETHCPKMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQSFHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAAQDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQALYNIISTWPHFKH
uniprot
proteins
function
FUNCTION: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. {ECO:0000269|PubMed:16354652}.
uniprot
proteins
mass_dalton
37611
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:16354652}.
uniprot
proteins
protein_family
N-acetylmuramoyl-L-alanine amidase 2 family
uniprot
proteins
pubmed
11461926
uniprot
proteins
pubmed
15140887
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15572450
uniprot
proteins
pubmed
16354652
uniprot
proteins
pubmed
16641493
uniprot
proteins
pubmed
16710414
uniprot
proteins
sequence_length
341
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16354652}.
uniprot
proteins