SFTPD
entrez
6441
canonical
uniprot
P35247
canonical
ensembl
ENSG00000133661
resolver
ensp
ENSP00000361366
resolver
ensp
ENSP00000535240
resolver
ensp
ENSP00000535241
resolver
ensp
ENSP00000535242
resolver
ensp
ENSP00000535243
resolver
ensp
ENSP00000535247
resolver
ensp
ENSP00000535248
resolver
ensp
ENSP00000535249
resolver
ensp
ENSP00000616758
resolver
ensp
ENSP00000616763
resolver
ensp
ENSP00000616766
resolver
enst
ENST00000372292
resolver
enst
ENST00000865181
resolver
enst
ENST00000865182
resolver
enst
ENST00000865183
resolver
enst
ENST00000865184
resolver
enst
ENST00000865188
resolver
enst
ENST00000865189
resolver
enst
ENST00000865190
resolver
enst
ENST00000946699
resolver
enst
ENST00000946707
resolver
genesymbol
SFTPD
resolver
genesymbol_syn
COLEC7
resolver
genesymbol_syn
PSPD
resolver
genesymbol_syn
SFTP4
resolver
hgnc
HGNC:10803
resolver
uniprot
Q5T0M3
resolver
uniprot
Q6FH08
resolver
uniprot
Q86YK9
resolver
uniprot
Q8TCD8
resolver
uniprot
Q9UCJ2
resolver
uniprot
Q9UCJ3
resolver
uniprot_entry
SFTPD_HUMAN
resolver
uniprot_sec
Q5T0M3
resolver
uniprot_sec
Q6FH08
resolver
uniprot_sec
Q86YK9
resolver
uniprot_sec
Q8TCD8
resolver
uniprot_sec
Q9UCJ2
resolver
uniprot_sec
Q9UCJ3
resolver
amino_acid_sequence
MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF
uniprot
proteins
function
FUNCTION: Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. {ECO:0000269|PubMed:23478426}.
uniprot
proteins
mass_dalton
37728
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.; PTM: Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates. {ECO:0000250}.; PTM: S-nitrosylation at Cys-35 and Cys-40 alters the quaternary structure which results in a pro-inflammatory chemoattractive signaling activity with macrophages. {ECO:0000250}.
uniprot
proteins
protein_family
SFTPD family
uniprot
proteins
pubmed
10368295
uniprot
proteins
pubmed
1339284
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
1898081
uniprot
proteins
pubmed
19100526
uniprot
proteins
pubmed
23478426
uniprot
proteins
pubmed
8424457
uniprot
proteins
pubmed
8428971
uniprot
proteins
sequence_length
375
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
uniprot
proteins