RAB6C
entrez
84084
canonical
uniprot
Q9H0N0
canonical
ensembl
ENSG00000222014
resolver
ensembl
ENSG00000292140
resolver
ensp
ENSP00000387307
resolver
ensp
ENSP00000517898
resolver
enst
ENST00000410061
resolver
enst
ENST00000709845
resolver
genesymbol
RAB6C
resolver
genesymbol_syn
WTH3
resolver
hgnc
HGNC:16525
resolver
uniprot
Q53RU3
resolver
uniprot
Q6FIF7
resolver
uniprot
Q9P128
resolver
uniprot_entry
RAB6C_HUMAN
resolver
uniprot_sec
Q53RU3
resolver
uniprot_sec
Q6FIF7
resolver
uniprot_sec
Q9P128
resolver
amino_acid_sequence
MSAGGDFGNPLRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIITLVGNRTDLADKRQVSVEEGERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDIKLEKPQEQTVSEGGCSCYSPMSSSTLPQKPPYSFIDCSVNIGLNLFPSLITFCNSSLLPVSWR
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB6C may be involved in the regulation of centrosome duplication and cell cycle progression. {ECO:0000250|UniProtKB:P20340, ECO:0000269|PubMed:17426708, ECO:0000269|PubMed:18992151, ECO:0000269|PubMed:20064528}.
uniprot
proteins
mass_dalton
28355
uniprot
proteins
mutagenesis
MUTAGEN 25; /note="A->G: No GTP binding. No GTP binding; when associated with T-45."; /evidence="ECO:0000269|PubMed:20064528"; MUTAGEN 45; /note="I->T: No GTP binding; when associated with G-25."; /evidence="ECO:0000269|PubMed:20064528
uniprot
proteins
protein_family
Rab family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
11054569
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
12007787
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16103095
uniprot
proteins
pubmed
17426708
uniprot
proteins
pubmed
18992151
uniprot
proteins
pubmed
20064528
uniprot
proteins
pubmed
21822290
uniprot
proteins
sequence_length
254
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16103095}. Cytoplasm {ECO:0000269|PubMed:16103095}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20064528}.
uniprot
proteins