ACOT9
entrez
23597
canonical
uniprot
Q9Y305
canonical
ensembl
ENSG00000123130
resolver
ensp
ENSP00000336580
resolver
ensp
ENSP00000368597
resolver
ensp
ENSP00000368605
resolver
genesymbol
ACOT9
resolver
hgnc
HGNC:17152
resolver
uniprot
B3KNC9
resolver
uniprot
B7ZM94
resolver
uniprot_entry
ACOT9_HUMAN
resolver
uniprot_sec
B3KNC9
resolver
uniprot_sec
B7ZM94
resolver
activity_regulation
ACTIVITY REGULATION: Strongly inhibited by NADH and CoA. {ECO:0000250|UniProtKB:Q9R0X4}.
uniprot
proteins
amino_acid_sequence
MRRAALRLCALGKGQLTPGRGLTQGPQNPKKQGIFHIHEVRDKLREIVGASTNWRDHVKAMEERKLLHSFLAKSQDGLPPRRMKDSYIEVLLPLGSEPELREKYLTVQNTVRFGRILEDLDSLGVLICYMHNKIHSAKMSPLSIVTALVDKIDMCKKSLSPEQDIKFSGHVSWVGKTSMEVKMQMFQLHGDEFCPVLDATFVMVARDSENKGPAFVNPLIPESPEEEELFRQGELNKGRRIAFSSTSLLKMAPSAEERTTIHEMFLSTLDPKTISFRSRVLPSNAVWMENSKLKSLEICHPQERNIFNRIFGGFLMRKAYELAWATACSFGGSRPFVVAVDDIMFQKPVEVGSLLFLSSQVCFTQNNYIQVRVHSEVASLQEKQHTTTNVFHFTFMSEKEVPLVFPKTYGESMLYLDGQRHFNSMSGPATLRKDYLVEP
uniprot
proteins
ec_number
3.1.2.-
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
function
FUNCTION: Mitochondrial acyl-CoA thioesterase. Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoA), regulating their respective intracellular levels. Regulates both mitochondrial lipid and amino acid metabolism. {ECO:0000250|UniProtKB:Q9R0X4}.
uniprot
proteins
mass_dalton
49902
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; fatty acid metabolism. {ECO:0000250|UniProtKB:Q9R0X4}.
uniprot
proteins
protein_family
Acyl coenzyme A hydrolase family
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18772397
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
439
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9R0X4}. Mitochondrion matrix {ECO:0000250|UniProtKB:Q9R0X4}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9R0X4}.
uniprot
proteins