Kcnc4
entrez
99738
canonical
uniprot
Q8R1C0
canonical
ensembl
ENSMUSG00000027895
resolver
ensp
ENSMUSP00000009617
resolver
ensp
ENSMUSP00000158751
resolver
ensp
ENSMUSP00000257715
resolver
enst
ENSMUST00000009617
resolver
enst
ENSMUST00000238670
resolver
genesymbol
Kcnc4
resolver
uniprot
A0A571BG98
resolver
uniprot_entry
A0A571BG98_MOUSE
resolver
uniprot_entry
KCNC4_MOUSE
resolver
amino_acid_sequence
MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGGGAGPGDEAGDDERELALQRLGPHEGGSGPGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNITSVRFRREVETEPILTYIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSEETSPRDSTYSDTSPPAREEGVVERKRADSKQNGDANAVLSDEEGAGLTQPLALAPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACADGSVRKEGNVEPKACVPVSHTCAL
uniprot
proteins
function
FUNCTION: Voltage-gated potassium channel that opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The channel displays rapid activation and inactivation kinetics. {ECO:0000250|UniProtKB:Q03721}.
uniprot
proteins
mass_dalton
68655
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of serine residues in the inactivation gate inhibits rapid channel closure. {ECO:0000250|UniProtKB:Q03721}.
uniprot
proteins
protein_family
C (Shaw) (TC 1.A.1.2) subfamily
uniprot
proteins
protein_family
Kv3.4/KCNC4 sub-subfamily
uniprot
proteins
protein_family
Potassium channel family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
628
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 231..251; /note="Helical; Name=Segment S1"; /evidence="ECO:0000255"; TRANSMEM 282..302; /note="Helical; Name=Segment S2"; /evidence="ECO:0000255"; TRANSMEM 317..337; /note="Helical; Name=Segment S3"; /evidence="ECO:0000255"; TRANSMEM 349..368; /note="Helical; Voltage-sensor; Name=Segment S4"; /evidence="ECO:0000255"; TRANSMEM 385..405; /note="Helical; Name=Segment S5"; /evidence="ECO:0000255"; TRANSMEM 456..476; /note="Helical; Name=Segment S6"; /evidence="ECO:0000255
uniprot
proteins