Isyna1
entrez
71780
canonical
uniprot
Q9JHU9
canonical
ensembl
ENSMUSG00000019139
resolver
ensp
ENSMUSP00000019283
resolver
ensp
ENSMUSP00000148077
resolver
enst
ENSMUST00000019283
resolver
enst
ENSMUST00000210005
resolver
genesymbol
Isyna1
resolver
genesymbol_syn
Ino1
resolver
uniprot_entry
INO1_MOUSE
resolver
amino_acid_sequence
MEPAAEILVDSPDVVYSPETIEARYEYRTTRVSREGGVLRVQPRATRFTFRTARQVPRLGVMLVGWGGNNGSTLTAAVLANRLRLTWPTRTGRKEANYYGSLTQAGTVNLGLDENGREVFVPFSALLPMVAPNDLVFDGWDISSLNLAEAMRRAQVLDCGLQEQLWPHMESLRPRPSVYIPEFIAANQTARADNLIPGTRAQQLEQIRKDIRDFRSSAGLDKVIVLWTANTERFCEVVPGRNDTAENLLHTIQLGLEVSPSTLFAVASILEDCAFLNGSPQNTLVPGALELASQRHVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGQNLSAPLQFRSKEVTKSSVVDDMVHSNHVLYAPGERPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDSLLAAPIMLDLVLLTELCQRVSFCTDSDPEPQGFHTVLSLLSFLFKAPLVPPGSPVVNALFRQRSCIENIFRACVGLPPQNHMLLEHKMERPGPGIKPGEVVATSPLPCKKEPTPATNGCTGDANGHPQAPTPKLSTA
uniprot
proteins
ec_number
5.5.1.4
uniprot
proteins
function
FUNCTION: Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity). {ECO:0000250|UniProtKB:Q9NPH2}.
uniprot
proteins
mass_dalton
60932
uniprot
proteins
pathway_participation
PATHWAY: Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.
uniprot
proteins
protein_family
Myo-inositol 1-phosphate synthase family
uniprot
proteins
pubmed
14613899
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17121280
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
557
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P11986}.
uniprot
proteins