Spring1
entrez
76792
canonical
uniprot
Q8BTG6
canonical
ensembl
ENSMUSG00000032840
resolver
ensp
ENSMUSP00000043410
resolver
enst
ENSMUST00000049138
resolver
genesymbol
Spring1
resolver
genesymbol_syn
Spring
resolver
uniprot_entry
SPRNG_MOUSE
resolver
amino_acid_sequence
MLNLAALLWRRLLRKRWVLALVFGLSLVYFLSSTFKQEERAVRDRNLLQVQDREQPIPWKVQFNLGNSSRPSNQCRNSVQGKHLLTDELGYVCERKDLLANGCCDVSVPSTKQYCCDGCLANGCCEAYEYCVSCCLQPSKQLLLERFLNRAAVAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAKYCYGESPPELFPA
uniprot
proteins
function
FUNCTION: Positively regulates hepatic SREBP signaling pathway by modulating the proper localization of SCAP (SREBP cleavage-activating protein) to the endoplasmic reticulum, thereby controlling the level of functional SCAP (PubMed:32111832). Plays a crucial role during embryogenesis (PubMed:32111832). {ECO:0000269|PubMed:32111832}.
uniprot
proteins
mass_dalton
23477
uniprot
proteins
protein_family
SPRING family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
32111832
uniprot
proteins
sequence_length
205
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9H741}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 17..35; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins