NACA2
entrez
342538
canonical
uniprot
Q9H009
canonical
ensembl
ENSG00000253506
resolver
ensp
ENSP00000427802
resolver
enst
ENST00000521764
resolver
genesymbol
NACA2
resolver
genesymbol_syn
NACAL
resolver
hgnc
HGNC:23290
resolver
uniprot
Q2VIR9
resolver
uniprot_entry
NACA2_HUMAN
resolver
uniprot_sec
Q2VIR9
resolver
amino_acid_sequence
MPGEATETVPATEQELPQSQAETGSGTASDSGESVPGIEEQDSTQTTTQKAWLVAAAEIDEEPVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIVFGEAKIQDLSQQAQLAAAEKFRVQGEAVGNIQENTQTPTVQEESEEEEVDETGVEVKDVKLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV
uniprot
proteins
function
FUNCTION: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
23223
uniprot
proteins
protein_family
NAC-alpha family
uniprot
proteins
pubmed
12406326
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16201836
uniprot
proteins
pubmed
19690332
uniprot
proteins
sequence_length
215
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
uniprot
proteins