Ccdc40
entrez
207607
canonical
uniprot
Q8BI79
canonical
ensembl
ENSMUSG00000039963
resolver
ensp
ENSMUSP00000158069
resolver
ensp
ENSMUSP00000213801
resolver
ensp
ENSMUSP00000213802
resolver
enst
ENSMUST00000236813
resolver
genesymbol
Ccdc40
resolver
genesymbol_syn
Lnks
resolver
uniprot
A0A494BAF9
resolver
uniprot
A2AFL0
resolver
uniprot
Q5U4C0
resolver
uniprot
Q8BI54
resolver
uniprot
Q8BI59
resolver
uniprot_entry
A0A494BAF9_MOUSE
resolver
uniprot_entry
CCD40_MOUSE
resolver
uniprot_entry
Q8BI54_MOUSE
resolver
uniprot_sec
A2AFL0
resolver
uniprot_sec
Q5U4C0
resolver
uniprot_sec
Q8BI59
resolver
amino_acid_sequence
MMDAEKVSTDGEAISEGEVGSNGETPPETEVEFIGETAPDTDVEFIGETSPGTDVEPTGESIQETEVESIGEATPGMDVEPIKKTMTELNVESIGEETSETDVDSIRKALRGIDLESITVAYPPKKAKHRKVRPQAEVESTGRAAPEGELEVSDHEKVEALLDELDELSEIVSSPEVSYSDISPLEMGEDDTNVSATSTDTFQQGIYEPIEPIEPTEPPEPAEPPKPAETPEDSTVRAPAHPYQRDFPMGARHRFRLSIMGSLTPSDTDDLPLETDEPPQQESVQSTPRALEETRIQFLDQVQSLSPEALLDRATEGSDEAEEEGSQLIVLDPDHPLMIRFQEALKGYLNRQMDKLKLDVQELDVATKQTRSQRQELGVNLYGVQQHLARLQMQLEKSHDRHSLVACERRRKEEELQCARSVYNKTCQTANEERKKLAALQTEVESLALHLFYMQNIEQDVRDDIQVMKQVVRKTETEKMHAEVEKKKQDLFVDQLTERSHQLEENIALFEAQYLSQAEDTRVLKKAVTEAITEIDTIAVEKKRILQQWTTSLVGMKHRNEAYKTVMDALRECQHQVKSTDSEIEVCKKSIMQEEEKNEKLARLLNRAETEATLVQKMTAQCLSKQEALQTEFNTYQLALQDTEEMLNKGYVEHSAVLSELQATRQAFHQEQELRQKMDMSMVDKLQEQGTSSKMTKYFHQLLRKLQKENTNLVTHLSKIDGDIAQATLDITNTNCKIDMHKKTLAEMDKEVKRFNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSELGGEEAGPLELEIKRLSKLTEEYNTGVAEAQMTWLRLQQELVQVTHEREEQLVSVDQLKKEVHIMEQKKLRIESKIAHEKKEQKIVSRHMRDLDNDLSKLNMLLDKNRCSSEELEQNNIATETEFLRTLKDSERETIQMQEKLMELSEEKATLLNSFMEAEHQIMLWEKKIQLAKEMRSSVDSETGQTEIRAMKAEIHRMKVRHGQLLKQQEKMIRDMELAVARRETIVVQAEGQSKIDKKVITKTEFHYQQRELQKKVREMHKATDDCTNTISELEETQKFLSSSLQEKQQLLSEMQATTDVLEEEINQLTALKRQNLLEIVTLQTRGKHLQAAIEGKYVFLHRNSRSQLMERKRLSVRLSQLNKVLSSVQEDYPQYQEVLQSIQQKIATKLETPEPS
uniprot
proteins
function
FUNCTION: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39. {ECO:0000250|UniProtKB:A8IQT2, ECO:0000250|UniProtKB:Q4G0X9}.
uniprot
proteins
mass_dalton
136772
uniprot
proteins
protein_family
CCDC40 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21131972
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1192
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21131972}. Cell projection, cilium {ECO:0000269|PubMed:21131972}. Note=Localizes to cytoplasm and motile cilium. {ECO:0000269|PubMed:21131972}.
uniprot
proteins