CHST9
entrez
83539
canonical
uniprot
Q7L1S5
canonical
ensembl
ENSG00000154080
resolver
ensp
ENSP00000462852
resolver
ensp
ENSP00000464655
resolver
ensp
ENSP00000480991
resolver
ensp
ENSP00000778695
resolver
genesymbol
CHST9
resolver
hgnc
HGNC:19898
resolver
uniprot
Q6UX69
resolver
uniprot
Q9BXH3
resolver
uniprot
Q9BXH4
resolver
uniprot
Q9BZW9
resolver
uniprot_entry
CHST9_HUMAN
resolver
uniprot_sec
Q6UX69
resolver
uniprot_sec
Q9BXH3
resolver
uniprot_sec
Q9BXH4
resolver
uniprot_sec
Q9BZW9
resolver
amino_acid_sequence
MQPSEMVMNPKQVFLSVLIFGVAGLLLFMYLQVWIEEQHTGRVEKRREQKVTSGWGPVKYLRPVPRIMSTEKIQEHITNQNPKFHMPEDVREKKENLLLNSERSTRLLTKTSHSQGGDQALSKSTGSPTEKLIEKRQGAKTVFNKFSNMNWPVDIHPLNKSLVKDNKWKKTEETQEKRRSFLQEFCKKYGGVSHHQSHLFHTVSRIYVEDKHKILYCEVPKAGCSNWKRILMVLNGLASSAYNISHNAVHYGKHLKKLDSFDLKGIYTRLNTYTKAVFVRDPMERLVSAFRDKFEHPNSYYHPVFGKAIIKKYRPNACEEALINGSGVKFKEFIHYLLDSHRPVGMDIHWEKVSKLCYPCLINYDFVGKFETLEEDANYFLQMIGAPKELKFPNFKDRHSSDERTNAQVVRQYLKDLTRTERQLIYDFYYLDYLMFNYTTPFL
uniprot
proteins
ec_number
2.8.2.-
uniprot
proteins
function
FUNCTION: Catalyzes the transfer of sulfate from 3'-phosphoadenylyl sulfate (PAPS) to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans (PubMed:11139592, PubMed:11445554). Transfers sulfate to the C-4 hydroxyl of terminal beta-1,4-linked GalNAc in the sequence GalNAc-beta-1,4GlcNAcbeta-R found on N-linked oligosaccharides and to the nonterminal beta-1,4-linked GalNAc in chondroitin and dermatan (PubMed:11445554). Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures (PubMed:11139592, PubMed:11445554). {ECO:0000269|PubMed:11139592, ECO:0000269|PubMed:11445554}.; FUNCTION: [Isoform 2]: Active against chondroitin but not against terminal beta-1,4-linked GalNAc. {ECO:0000269|PubMed:11139592}.
uniprot
proteins
mass_dalton
52055
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; carbohydrate sulfation. {ECO:0000305|PubMed:11445554}.
uniprot
proteins
protein_family
Sulfotransferase 2 family
uniprot
proteins
pubmed
11139592
uniprot
proteins
pubmed
11445554
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16177791
uniprot
proteins
pubmed
28132690
uniprot
proteins
sequence_length
443
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 13..33; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins