Nepro
entrez
212547
canonical
uniprot
Q8R2U2
canonical
ensembl
ENSMUSG00000036208
resolver
ensp
ENSMUSP00000038779
resolver
enst
ENSMUST00000048788
resolver
genesymbol
Nepro
resolver
genesymbol
Rmp64
resolver
genesymbol_syn
BC027231
resolver
genesymbol_syn
Nepro
resolver
uniprot
Q3TS42
resolver
uniprot_entry
Q3TS42_MOUSE
resolver
uniprot_entry
RMP64_MOUSE
resolver
amino_acid_sequence
MAAAVRPGAEPWNRVRIPQAGNCSTLTVRDPSATLDICTAAVTKGCHLVTQSLKSQTLDAEVDVLCSVLYSNHNRLGHHKPHLALRQVEQCLKRLKHMNLEGSIEDLSQLLSANATQPGATENRVVPSQPVVEVVLMKVLGGCKLLLRLLDCCCKAFLLTVKHLGLKEFIILNLVMVGLVSRLWVLHKGLLRRLISLYEPLLSLRQEISSIHPMPYFKDFAFPSDITDFLGPSYLEVFKVKTPAASATKGVTKLLNKLFLMREQLPKMNEDTLDRLSKPSEQMTSNPQSTVDLGQPVKACKRTRKEKPLGFDLRAFCTRLGNKATQETNRDFKYSQSKLKTTKLPSQQLRTHWANDTVQRIRKTKTFAQLSEEIEMAIVWSRSKKLKTQATFLGNKLLKSNRFRHVESQGYSLTKKLQCMKTSLCNCLLRGSRTSTSEHPPRQRRSKYKVLSRQRKPQRKLQSTLLKETQQVPEGTLKNTRDSSAKRRCSGTVQRSDVCPNGKQVLRKLAKPDLKTKVVVHGNLTGGSRNESGFQAKTQMHTHNAPDTAKEADDIDDIFALMGV
uniprot
proteins
function
FUNCTION: Specific component of the MRP ribonucleoprotein endoribonuclease, Rnase/Mrp complex, a ribonucleoprotein complex involved in pre-rRNA processing (By similarity). May play a role in cortex development as part of the Notch signaling pathway. Downstream of Notch may repress the expression of proneural genes and inhibit neuronal differentiation thereby maintaining neural progenitors. May also play a role in preimplentation embryo development (PubMed:19906856, PubMed:26178919). {ECO:0000250|UniProtKB:Q6NW34, ECO:0000269|PubMed:19906856, ECO:0000269|PubMed:26178919}.
uniprot
proteins
mass_dalton
63394
uniprot
proteins
protein_family
RMP64 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19906856
uniprot
proteins
pubmed
26178919
uniprot
proteins
sequence_length
564
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19906856}. Nucleus, nucleolus {ECO:0000269|PubMed:26178919}.
uniprot
proteins