NPFFR1
entrez
64106
canonical
uniprot
Q9GZQ6
canonical
ensembl
ENSG00000148734
resolver
ensp
ENSP00000277942
resolver
enst
ENST00000277942
resolver
genesymbol
NPFFR1
resolver
genesymbol_syn
GPR147
resolver
genesymbol_syn
NPFF1
resolver
hgnc
HGNC:17425
resolver
uniprot
A2RRF0
resolver
uniprot
Q8NGR0
resolver
uniprot
Q96RN3
resolver
uniprot_entry
NPFF1_HUMAN
resolver
uniprot_sec
A2RRF0
resolver
uniprot_sec
Q8NGR0
resolver
uniprot_sec
Q96RN3
resolver
amino_acid_sequence
MEGEPSQPPNSSWPLSQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVAHHGLPREGPGCSHLPLTIPAWDI
uniprot
proteins
function
FUNCTION: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. {ECO:0000269|PubMed:11024015, ECO:0000269|PubMed:11025660}.
uniprot
proteins
mass_dalton
47819
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
11024015
uniprot
proteins
pubmed
11025660
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11024015}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 44..64; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 81..101; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 118..138; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 159..179; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 215..235; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 272..292; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 308..328; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins