KLF7
entrez
8609
canonical
uniprot
O75840
canonical
ensembl
ENSG00000118263
resolver
ensp
ENSP00000309570
resolver
ensp
ENSP00000387510
resolver
ensp
ENSP00000398572
resolver
ensp
ENSP00000413590
resolver
ensp
ENSP00000515454
resolver
ensp
ENSP00000544507
resolver
ensp
ENSP00000544508
resolver
ensp
ENSP00000749527
resolver
genesymbol
KLF7
resolver
genesymbol_syn
UKLF
resolver
hgnc
HGNC:6350
resolver
uniprot
B2RB03
resolver
uniprot
B7Z4F7
resolver
uniprot
C9JF04
resolver
uniprot
E7EWH1
resolver
uniprot
L0R4P2
resolver
uniprot
Q7Z3H8
resolver
uniprot
Q96E51
resolver
uniprot_entry
KLF7_HUMAN
resolver
uniprot_sec
B2RB03
resolver
uniprot_sec
B7Z4F7
resolver
uniprot_sec
C9JF04
resolver
uniprot_sec
E7EWH1
resolver
uniprot_sec
L0R4P2
resolver
uniprot_sec
Q7Z3H8
resolver
uniprot_sec
Q96E51
resolver
amino_acid_sequence
MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQTEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRDKLLSETCLSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDGTVTLKLVAKKAALSSVKVGGVATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI
uniprot
proteins
function
FUNCTION: Transcriptional factor (PubMed:16339272, PubMed:9774444). Plays a critical role in neuronal morphogenesis and survival of sensory neurons (By similarity). Represses the corneal epithelium differentiation (PubMed:28916725). Also acts as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells (PubMed:16339272). Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin (PubMed:16339272). {ECO:0000250|UniProtKB:Q99JB0, ECO:0000269|PubMed:16339272, ECO:0000269|PubMed:28916725, ECO:0000269|PubMed:9774444}.
uniprot
proteins
mass_dalton
33362
uniprot
proteins
protein_family
Krueppel C2H2-type zinc-finger protein family
uniprot
proteins
pubmed
11230166
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16339272
uniprot
proteins
pubmed
23134681
uniprot
proteins
pubmed
28916725
uniprot
proteins
pubmed
29251763
uniprot
proteins
pubmed
31375868
uniprot
proteins
pubmed
9774444
uniprot
proteins
sequence_length
302
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9774444}.
uniprot
proteins