NUTM1
entrez
256646
canonical
uniprot
Q86Y26
canonical
ensembl
ENSG00000184507
resolver
ensembl
ENSG00000291987
resolver
ensp
ENSP00000329448
resolver
ensp
ENSP00000407031
resolver
ensp
ENSP00000444896
resolver
ensp
ENSP00000517710
resolver
ensp
ENSP00000517711
resolver
ensp
ENSP00000517712
resolver
ensp
ENSP00000517713
resolver
enst
ENST00000709471
resolver
enst
ENST00000709472
resolver
enst
ENST00000709473
resolver
enst
ENST00000709474
resolver
genesymbol
NUTM1
resolver
genesymbol_syn
C15orf55
resolver
genesymbol_syn
NUT
resolver
hgnc
HGNC:29919
resolver
uniprot
A0AAG2UVG0
resolver
uniprot
A0AAG2UVR5
resolver
uniprot
A0AAG2UXE6
resolver
uniprot
B4DZ00
resolver
uniprot
B7Z7Y4
resolver
uniprot
E7EVE8
resolver
uniprot
F5H4I6
resolver
uniprot
Q86YS8
resolver
uniprot
Q8N7F2
resolver
uniprot
Q9NTB3
resolver
uniprot_entry
A0AAG2UVG0_HUMAN
resolver
uniprot_entry
A0AAG2UVR5_HUMAN
resolver
uniprot_entry
A0AAG2UXE6_HUMAN
resolver
uniprot_entry
NUTM1_HUMAN
resolver
uniprot_sec
B4DZ00
resolver
uniprot_sec
B7Z7Y4
resolver
uniprot_sec
E7EVE8
resolver
uniprot_sec
F5H4I6
resolver
uniprot_sec
Q86YS8
resolver
uniprot_sec
Q8N7F2
resolver
uniprot_sec
Q9NTB3
resolver
amino_acid_sequence
MASDGASALPGPDMSMKPSAAPSPSPALPFLPPTSDPPDHPPREPPPQPIMPSVFSPDNPLMLSAFPSSLLVTGDGGPCLSGAGAGKVIVKVKTEGGSAEPSQTQNFILTQTALNSTAPGTPCGGLEGPAPPFVTASNVKTILPSKAVGVSQEGPPGLPPQPPPPVAQLVPIVPLEKAWPGPHGTTGEGGPVATLSKPSLGDRSKISKDVYENFRQWQRYKALARRHLSQSPDTEALSCFLIPVLRSLARLKPTMTLEEGLPLAVQEWEHTSNFDRMIFYEMAERFMEFEAEEMQIQNTQLMNGSQGLSPATPLKLDPLGPLASEVCQQPVYIPKKAASKTRAPRRRQRKAQRPPAPEAPKEIPPEAVKEYVDIMEWLVGTHLATGESDGKQEEEGQQQEEEGMYPDPGLLSYINELCSQKVFVSKVEAVIHPQFLADLLSPEKQRDPLALIEELEQEEGLTLAQLVQKRLMALEEEEDAEAPPSFSGAQLDSSPSGSVEDEDGDGRLRPSPGLQGAGGAACLGKVSSSGKRAREVHGGQEQALDSPRGMHRDGNTLPSPSSWDLQPELAAPQGTPGPLGVERRGSGKVINQVSLHQDGHLGGAGPPGHCLVADRTSEALPLCWQGGFQPESTPSLDAGLAELAPLQGQGLEKQVLGLQKGQQTGGRGVLPQGKEPLAVPWEGSSGAMWGDDRGTPMAQSYDQNPSPRAAGERDDVCLSPGVWLSSEMDAVGLELPVQIEEVIESFQVEKCVTEYQEGCQGLGSRGNISLGPGETLVPGDTESSVIPCGGTVAAAALEKRNYCSLPGPLRANSPPLRSKENQEQSCETVGHPSDLWAEGCFPLLESGDSTLGSSKETLPPTCQGNLLIMGTEDASSLPEASQEAGSRGNSFSPLLETIEPVNILDVKDDCGLQLRVSEDTCPLNVHSYDPQGEGRVDPDLSKPKNLAPLQESQESYTTGTPKATSSHQGLGSTLPRRGTRNAIVPRETSVSKTHRSADRAKGKEKKKKEAEEEDEELSNFAYLLASKLSLSPREHPLSPHHASGGQGSQRASHLLPAGAKGPSKLPYPVAKSGKRALAGGPAPTEKTPHSGAQLGVPREKPLALGVVRPSQPRKRRCDSFVTGRRKKRRRSQ
uniprot
proteins
disease_involvement
DISEASE: Note=A chromosomal aberration involving NUTM1 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUTM1 fusion protein. {ECO:0000269|PubMed:12543779}.; DISEASE: Note=A chromosomal aberration involving NUTM1 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUTM1 fusion protein. {ECO:0000269|PubMed:12543779}.
uniprot
proteins
function
FUNCTION: Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites. {ECO:0000269|PubMed:30447097}.
uniprot
proteins
mass_dalton
120314
uniprot
proteins
mutagenesis
MUTAGEN 1046; /note="Q->R: Abolishes methylation by N6AMT1."; /evidence="ECO:0000269|PubMed:26797129
uniprot
proteins
post_translational_modification
PTM: Methylated at Gln-1046 by N6AMT1. {ECO:0000269|PubMed:26797129}.; PTM: Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export. {ECO:0000269|PubMed:17934517}.
uniprot
proteins
protein_family
NUT family
uniprot
proteins
pubmed
12543779
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
17934517
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
26797129
uniprot
proteins
pubmed
30447097
uniprot
proteins
sequence_length
1132
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17934517}. Nucleus {ECO:0000269|PubMed:17934517}. Note=Shuttles between nucleus and cytoplasm. {ECO:0000269|PubMed:17934517}.
uniprot
proteins