Get1
entrez
71446
canonical
uniprot
Q8K0D7
canonical
ensembl
ENSMUSG00000023147
resolver
ensp
ENSMUSP00000023913
resolver
enst
ENSMUST00000023913
resolver
genesymbol
Get1
resolver
genesymbol_syn
Wrb
resolver
uniprot
Q3TA55
resolver
uniprot
Q9D1W0
resolver
uniprot_entry
GET1_MOUSE
resolver
uniprot_sec
Q3TA55
resolver
uniprot_sec
Q9D1W0
resolver
amino_acid_sequence
MSASETDRWAWLLVLSFVFGCNLLRILLPSLSSFISRVLQKDAEQESQMRAEIQGMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWFISVAFYILQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGIGITCWILVCNKVVAIVLHPFS
uniprot
proteins
function
FUNCTION: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with CAMLG/GET2, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required to ensure correct topology and ER insertion of CAMLG. {ECO:0000250|UniProtKB:O00258}.
uniprot
proteins
mass_dalton
19867
uniprot
proteins
protein_family
WRB/GET1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
174
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O00258}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 100..120; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 149..169; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins