Mmp20
entrez
30800
canonical
uniprot
P57748
canonical
ensembl
ENSMUSG00000018620
resolver
ensp
ENSMUSP00000034487
resolver
enst
ENSMUST00000034487
resolver
genesymbol
Mmp20
resolver
uniprot
A7MCV5
resolver
uniprot_entry
MMP20_MOUSE
resolver
uniprot_sec
A7MCV5
resolver
amino_acid_sequence
MKVLPASGLAVLVTALKFATADPNLLAATPRTFRSNYHLAQAYLDKYYTKKGGPQAGEMVARESNPMIRRIKELQIFFGLKVTGKLDQNTMNVIKKPRCGVPDVANYRLFPGEPKWKKNILTYRISKYTPSMSPTEVDKAIQMALHAWSTAVPLNFVRINSGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALYGPRKIFPGKPTMPHIPPHKPSIPDLCDSSSSFDAVTMLGKELLFFKDRIFWRRQVHLPTGIRPSTITSSFPQLMSNVDAAYEVAERGIAFFFKGPHYWVTRGFHMQGPPRTIYDFGFPRHVQRIDAAVYLKEPQKTLFFVGEEYYSYDERKKKMEKDYPKNTEEEFSGVSGHIDAAVELNGYIYFFSGRKTFKYDTEKEDVVSVVKSSSWIGC
uniprot
proteins
ec_number
3.4.24.-
uniprot
proteins
function
FUNCTION: Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site. {ECO:0000250|UniProtKB:O60882}.
uniprot
proteins
mass_dalton
54373
uniprot
proteins
post_translational_modification
PTM: Autoactivates at least at the 106-Asn-|-Tyr-107 site. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase M10A family
uniprot
proteins
pubmed
10610728
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21285247
uniprot
proteins
sequence_length
482
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
uniprot
proteins