Rprm
entrez
67874
canonical
uniprot
Q9JJ72
canonical
ensembl
ENSMUSG00000075334
resolver
ensp
ENSMUSP00000097667
resolver
enst
ENSMUST00000100089
resolver
genesymbol
Rprm
resolver
uniprot
Q8K1G8
resolver
uniprot_entry
RPRM_MOUSE
resolver
uniprot_sec
Q8K1G8
resolver
amino_acid_sequence
MNSVLGNQTDVAGLFLVNSSEALERAVRCCTQASVVTDDGFAEGGPDERSLYIMRVVQIAVMCVLSLTVVFGIFFLGCNLLIKSEGMINFLVKDRRPSKEVEAVVVGPY
uniprot
proteins
function
FUNCTION: May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex. {ECO:0000269|PubMed:10930422}.
uniprot
proteins
mass_dalton
11820
uniprot
proteins
protein_family
Reprimo family
uniprot
proteins
pubmed
10930422
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
109
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:10930422}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins