CXCR1
entrez
3577
canonical
uniprot
P25024
canonical
ensembl
ENSG00000163464
resolver
ensp
ENSP00000295683
resolver
enst
ENST00000295683
resolver
genesymbol
CXCR1
resolver
genesymbol_syn
CMKAR1
resolver
genesymbol_syn
IL8RA
resolver
hgnc
HGNC:6026
resolver
uniprot
B2R6Q3
resolver
uniprot
Q2YEF8
resolver
uniprot
Q2YEG4
resolver
uniprot
Q2YEG5
resolver
uniprot
Q2YEG7
resolver
uniprot
Q2YEG8
resolver
uniprot
Q53R18
resolver
uniprot
Q6IN95
resolver
uniprot
Q8N6T6
resolver
uniprot
Q9P2T8
resolver
uniprot
Q9P2T9
resolver
uniprot
Q9P2U0
resolver
uniprot
Q9P2U1
resolver
uniprot
Q9P2U2
resolver
uniprot_entry
CXCR1_HUMAN
resolver
uniprot_sec
B2R6Q3
resolver
uniprot_sec
Q2YEF8
resolver
uniprot_sec
Q2YEG4
resolver
uniprot_sec
Q2YEG5
resolver
uniprot_sec
Q2YEG7
resolver
uniprot_sec
Q2YEG8
resolver
uniprot_sec
Q53R18
resolver
uniprot_sec
Q6IN95
resolver
uniprot_sec
Q8N6T6
resolver
uniprot_sec
Q9P2T8
resolver
uniprot_sec
Q9P2T9
resolver
uniprot_sec
Q9P2U0
resolver
uniprot_sec
Q9P2U1
resolver
uniprot_sec
Q9P2U2
resolver
amino_acid_sequence
MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
uniprot
proteins
function
FUNCTION: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor (PubMed:1840701). Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698). {ECO:0000269|PubMed:1840701, ECO:0000269|PubMed:8662698}.
uniprot
proteins
mass_dalton
39791
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10368283
uniprot
proteins
pubmed
11196695
uniprot
proteins
pubmed
1379593
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16205979
uniprot
proteins
pubmed
1840701
uniprot
proteins
pubmed
7929358
uniprot
proteins
pubmed
8384312
uniprot
proteins
pubmed
8486366
uniprot
proteins
pubmed
8662698
uniprot
proteins
sequence_length
350
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 40..66; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 76..96; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 112..133; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 155..174; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 200..220; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 243..264; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 286..308; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins