POGLUT3
entrez
143888
canonical
uniprot
Q7Z4H8
canonical
ensembl
ENSG00000178202
resolver
ensp
ENSP00000315386
resolver
ensp
ENSP00000413429
resolver
ensp
ENSP00000516431
resolver
ensp
ENSP00000516432
resolver
enst
ENST00000706523
resolver
enst
ENST00000706524
resolver
genesymbol
POGLUT3
resolver
genesymbol_syn
KDELC2
resolver
hgnc
HGNC:28496
resolver
uniprot
A0A9L9PX09
resolver
uniprot
A0A9L9PY40
resolver
uniprot
Q6UWW2
resolver
uniprot
Q6ZUM9
resolver
uniprot
Q8N7L8
resolver
uniprot
Q8NE24
resolver
uniprot_entry
A0A9L9PX09_HUMAN
resolver
uniprot_entry
A0A9L9PY40_HUMAN
resolver
uniprot_entry
PLGT3_HUMAN
resolver
uniprot_sec
Q6UWW2
resolver
uniprot_sec
Q6ZUM9
resolver
uniprot_sec
Q8N7L8
resolver
uniprot_sec
Q8NE24
resolver
amino_acid_sequence
MRRLPRALLLQLRLALLVAAGAPEVLVSAPRSLVWGPGLQAAVVLPVRYFYLQAVNSEGQNLTRSPAGETPFKVVVKSLSPKELVRIHVPKPLDRNDGTFLMRYRMYETVDEGLKIEVLYGDEHVAQSPYILKGPVYHEYCECPEDPQAWQKTLSCPTKEPQIAKDFASFPSINLQQMLKEVPKRFGDERGAIVHYTILNNHVYRRSLGKYTDFKMFSDEILLSLTRKVLLPDLEFYVNLGDWPLEHRKVNGTPSPIPIISWCGSLDSRDVVLPTYDITHSMLEAMRGVTNDLLSIQGNTGPSWINKTERAFFRGRDSREERLQLVQLSKENPQLLDAGITGYFFFQEKEKELGKAKLMGFFDFFKYKYQVNVDGTVAAYRYPYLMLGDSLVLKQDSPYYEHFYMALEPWKHYVPIKRNLSDLLEKVKWAKENDEEAKKIAKEGQLMARDLLQPHRLYCYYYQVLQKYAERQSSKPEVRDGMELVPQPEDSTAICQCHRKKPSREEL
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
ec_number
2.4.2.-
uniprot
proteins
function
FUNCTION: Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed:30127001). Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed:30127001). Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1 (PubMed:30127001, PubMed:34411563). May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed:30127001). {ECO:0000269|PubMed:30127001, ECO:0000269|PubMed:34411563}.
uniprot
proteins
mass_dalton
58572
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000269|PubMed:30127001}.
uniprot
proteins
protein_family
KDELC family
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
30127001
uniprot
proteins
pubmed
34411563
uniprot
proteins
sequence_length
507
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
uniprot
proteins