Thpo
entrez
21832
canonical
uniprot
P40226
canonical
ensembl
ENSMUSG00000022847
resolver
ensp
ENSMUSP00000075756
resolver
ensp
ENSMUSP00000111097
resolver
ensp
ENSMUSP00000155914
resolver
ensp
ENSMUSP00000179453
resolver
genesymbol
Thpo
resolver
uniprot
Q543R9
resolver
uniprot_entry
Q543R9_MOUSE
resolver
uniprot_entry
TPO_MOUSE
resolver
amino_acid_sequence
MELTDLLLAAMLLAVARLTLSSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET
uniprot
proteins
function
FUNCTION: Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. {ECO:0000250|UniProtKB:P40225}.
uniprot
proteins
mass_dalton
37836
uniprot
proteins
protein_family
EPO/TPO family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22284746
uniprot
proteins
pubmed
7849319
uniprot
proteins
pubmed
8020099
uniprot
proteins
pubmed
8202158
uniprot
proteins
sequence_length
356
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P40225}.
uniprot
proteins