Hsd3b
entrez
682974
canonical
uniprot
P22072
canonical
ensembl
ENSRNOG00000080702
resolver
ensembl
ENSRNOG00055032809
resolver
ensembl
ENSRNOG00060013844
resolver
ensembl
ENSRNOG00065031015
resolver
ensp
ENSRNOP00000075324
resolver
ensp
ENSRNOP00000095326
resolver
ensp
ENSRNOP00055046843
resolver
ensp
ENSRNOP00060018795
resolver
ensp
ENSRNOP00065043952
resolver
enst
ENSRNOT00000086835
resolver
enst
ENSRNOT00000105757
resolver
enst
ENSRNOT00055056738
resolver
enst
ENSRNOT00060023643
resolver
enst
ENSRNOT00065053465
resolver
genesymbol
Hsd3b
resolver
uniprot_entry
3BHS2_RAT
resolver
amino_acid_sequence
MPGWSCLVTGAGGFVGQRIIRMLVQEKELQEVRALDKVFRPETKEEFSKLQTKAKVTMLEGDILDAQYLRRACQGISVVIHTASVMDFSRVLPRQTILDVNLKGTQNLLEAGIHASVPAFIYCSTVDVAGPNSYKKTILNGREEEHHESTWSNPYPYSKKMAEKAVLAANGSILKNGGTLHTCALRPMYIYGERGQFLSRIIIMALKNKGVLNVTGKFSIVNPVYVGNVAWAHILAARGLRDPKKSQNIQGQFYYISDDTPHQSYDDLNCTLSKEWGLRLDSSWSLPLPLLYWLAFLLETVSFLLRPFYNYRPPFNCHLVTLSNSKFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
uniprot
proteins
ec_number
1.1.1.145
uniprot
proteins
ec_number
5.3.3.1
uniprot
proteins
function
FUNCTION: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
uniprot
proteins
mass_dalton
42277
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; steroid biosynthesis.
uniprot
proteins
protein_family
3-beta-HSD family
uniprot
proteins
pubmed
1944305
uniprot
proteins
pubmed
1985917
uniprot
proteins
sequence_length
373
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 288..308; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins