Mterf1a
entrez
545725
canonical
uniprot
Q8CHZ9
canonical
ensembl
ENSMUSG00000040429
resolver
ensp
ENSMUSP00000046017
resolver
ensp
ENSMUSP00000113306
resolver
ensp
ENSMUSP00000221746
resolver
ensp
ENSMUSP00000365136
resolver
enst
ENSMUST00000044746
resolver
enst
ENSMUST00000117463
resolver
genesymbol
Mterf1a
resolver
genesymbol_syn
Mterf
resolver
genesymbol_syn
Mterf1
resolver
uniprot
Q63ZX5
resolver
uniprot
Q8C7T1
resolver
uniprot_entry
MTF1A_MOUSE
resolver
uniprot_sec
Q63ZX5
resolver
uniprot_sec
Q8C7T1
resolver
amino_acid_sequence
MASRNIWCVRRNFLFDLRDWMLQYSAEVFLKSISFRPFSAECDSKDKESLEEEREDLLSNLVTMGVDIDMARRRQPGVFNKAVTNEQELKLFLLSKGASDKVIGSIISRYPRAITRTPESLSKRWDLWRKIMASDLEIVNILERSPESFFRSNNNLNLENNIKFLCSVGLTHKCLCRLLTNAPRTFSNSLNLNKQMVEFLQETGMSLGHNDPRDFVRKIISKNPSILIQSTKRVKTNIEFLQSTFNLNKRDLLLLICGPGARILDLSNDCTKKNYTNIRERLLSLGCSEEEVQRFVLSYLNMVFLSEKKFNDKIDCLIEEKISASQIIENPRILDSSINTLKTRIRELSHAGYDLSTSSIALLSWSQRRYEAKLKRLCG
uniprot
proteins
function
FUNCTION: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand. {ECO:0000269|PubMed:23562081}.
uniprot
proteins
mass_dalton
43815
uniprot
proteins
post_translational_modification
PTM: Phosphoprotein with mostly four phosphate groups. While the DNA-binding activity is unaffected by the phosphorylation state, only the phosphorylated form of the protein is active for termination activity. Functioning seems to be regulated by phosphorylation (By similarity). {ECO:0000250}.
uniprot
proteins
protein_family
MTERF family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15582606
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
23562081
uniprot
proteins
sequence_length
379
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:15582606}.
uniprot
proteins