Ppp2r2d
entrez
52432
canonical
uniprot
Q925E7
canonical
ensembl
ENSMUSG00000041769
resolver
ensp
ENSMUSP00000040321
resolver
ensp
ENSMUSP00000119004
resolver
ensp
ENSMUSP00000228896
resolver
enst
ENSMUST00000041097
resolver
enst
ENSMUST00000155672
resolver
genesymbol
Ppp2r2d
resolver
genesymbol_syn
D7Ertd753e
resolver
genesymbol_syn
Kiaa1541
resolver
uniprot
F6RV17
resolver
uniprot
Q6ZPN5
resolver
uniprot_entry
2ABD_MOUSE
resolver
uniprot_entry
F6RV17_MOUSE
resolver
uniprot_sec
Q6ZPN5
resolver
amino_acid_sequence
MAGAGGGGCPAGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDVTLEASRENSKPRASLKPRKVCTGGKRKKDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN
uniprot
proteins
function
FUNCTION: Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit (PubMed:39003739). Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67 (PubMed:39003739). The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis (By similarity). {ECO:0000250|UniProtKB:Q7ZX64, ECO:0000269|PubMed:39003739}.
uniprot
proteins
mass_dalton
51957
uniprot
proteins
protein_family
Phosphatase 2A regulatory subunit B family
uniprot
proteins
pubmed
14621295
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
39003739
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P56932}.
uniprot
proteins