TRMT2B
entrez
79979
canonical
uniprot
Q96GJ1
canonical
ensembl
ENSG00000188917
resolver
ensp
ENSP00000362026
resolver
ensp
ENSP00000362027
resolver
ensp
ENSP00000362030
resolver
ensp
ENSP00000438134
resolver
ensp
ENSP00000532885
resolver
ensp
ENSP00000532893
resolver
ensp
ENSP00000598920
resolver
genesymbol
TRMT2B
resolver
genesymbol_syn
CXorf34
resolver
hgnc
HGNC:25748
resolver
uniprot
A6NDG5
resolver
uniprot
A6NEI9
resolver
uniprot
A6NMG6
resolver
uniprot
Q5JPF0
resolver
uniprot
Q5JVY6
resolver
uniprot
Q96HU7
resolver
uniprot
Q96IH9
resolver
uniprot
Q9H9K2
resolver
uniprot_entry
TRM2B_HUMAN
resolver
uniprot_sec
A6NDG5
resolver
uniprot_sec
A6NEI9
resolver
uniprot_sec
A6NMG6
resolver
uniprot_sec
Q5JPF0
resolver
uniprot_sec
Q5JVY6
resolver
uniprot_sec
Q96HU7
resolver
uniprot_sec
Q96IH9
resolver
uniprot_sec
Q9H9K2
resolver
amino_acid_sequence
MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTPHCELVLLFTR
uniprot
proteins
ec_number
2.1.1.-
uniprot
proteins
ec_number
2.1.1.35
uniprot
proteins
function
FUNCTION: Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and 12S rRNA (PubMed:31948311, PubMed:34556860). Catalyzes the methylation of uridine at position 54 (m5U54) in all tRNAs (PubMed:31948311). Specifically methylates the uridine in position 429 of 12S rRNA (m5U429) (PubMed:31948311). Does not affect RNA stability or mitochondrial translation (PubMed:31948311). {ECO:0000269|PubMed:31948311, ECO:0000269|PubMed:34556860}.
uniprot
proteins
mass_dalton
56476
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
RNA M5U methyltransferase family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
27184847
uniprot
proteins
pubmed
31948311
uniprot
proteins
pubmed
34556860
uniprot
proteins
sequence_length
504
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:31948311}.; SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion matrix {ECO:0000269|PubMed:27184847}.
uniprot
proteins