Sugct
entrez
361253
canonical
uniprot
Q68FU4
canonical
ensembl
ENSRNOG00000066247
resolver
ensembl
ENSRNOG00055011142
resolver
ensembl
ENSRNOG00060014508
resolver
ensembl
ENSRNOG00065021750
resolver
ensp
ENSRNOP00000079174
resolver
ensp
ENSRNOP00000100791
resolver
ensp
ENSRNOP00000102580
resolver
ensp
ENSRNOP00000109393
resolver
ensp
ENSRNOP00055015262
resolver
ensp
ENSRNOP00060019758
resolver
ensp
ENSRNOP00065029786
resolver
enst
ENSRNOT00000137064
resolver
enst
ENSRNOT00000139022
resolver
enst
ENSRNOT00000146890
resolver
enst
ENSRNOT00055018905
resolver
enst
ENSRNOT00060024802
resolver
enst
ENSRNOT00065036973
resolver
genesymbol
Sugct
resolver
uniprot
A0ABK0LC44
resolver
uniprot
A0ABK0LF49
resolver
uniprot
A0ABK0LLM2
resolver
uniprot
F1LXJ6
resolver
uniprot_entry
A0ABK0LC44_RAT
resolver
uniprot_entry
A0ABK0LF49_RAT
resolver
uniprot_entry
A0ABK0LLM2_RAT
resolver
uniprot_entry
SUCHY_RAT
resolver
uniprot_sec
F1LXJ6
resolver
amino_acid_sequence
MLRMLARAVAFRRSGRGQAGGRGLWTGRPQSDCDSMKPLEGVRILDLTRVLAGPFATMNLGDLGAEVIKVERPGAGDDTRSWGPPFVNTESTYFLSVNRNKKSIAVNIKDPRGVRIVKELAAICDVFVENYVPGKLSEMGLGYADIDKIAPHIVYCSITGYGQTGPMSHRAGYDAIASAMSGLMHITGPEDGDPVRPGVAMTDLATGLFAYGAIMAGLIQRYRTGKGLFIDCNLLSSQVACLTQVAANYLIGQKEAKRWGTAHGSIVPYQAFKTKDGYLVIGAGNNQQFAVLCKILNLPELIDDSKYRTNHLRVQNRKELVKILSARFAEEVTAKWLCLFEGSGIPYGPINSLKDVFSEAQVLHNGLVMEMNHPTVGKISVPGPAVRYSKFKMSEAKPPPLLGQHTRHILKEVLRYDEGVIGELLCSGVIEQHETE
uniprot
proteins
ec_number
2.8.3.-
uniprot
proteins
ec_number
2.8.3.13
uniprot
proteins
function
FUNCTION: Coenzyme A (CoA) transferase that reversibly catalyzes the transfer of a CoA moiety from a dicarboxyl-CoA to a dicarboxylate in a metabolite recycling process. Displays preference for succinyl-CoA and glutarate-CoA as dicarboxyl-CoA donors and glutarate, succinate, adipate/hexanedioate, itaconate and 3-hydroxy-3-methylglutarate as dicarboxylate acceptors (By similarity). Acts on intermediates or end products of lysine and tryptophan degradation pathway, in particular catalyzes succinyl-CoA-dependent reesterification of free glutarate into glutaryl-CoA to prevent renal excretion of glutarate (By similarity). Upon inflammation, may convert macrophage-derived itaconate to itaconyl-CoA in erythroid precursors where it negatively regulates the TCA cycle and heme synthesis to limit erythroid differentiation in the context of stress erythropoiesis (By similarity). {ECO:0000250|UniProtKB:Q9HAC7}.
uniprot
proteins
mass_dalton
47549
uniprot
proteins
protein_family
CoA-transferase III family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
436
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9HAC7}.
uniprot
proteins