RGS3
entrez
5998
canonical
uniprot
P49796
canonical
ensembl
ENSG00000138835
resolver
ensp
ENSP00000312844
resolver
ensp
ENSP00000340284
resolver
ensp
ENSP00000343359
resolver
ensp
ENSP00000363249
resolver
ensp
ENSP00000363255
resolver
ensp
ENSP00000378141
resolver
ensp
ENSP00000420356
resolver
ensp
ENSP00000479017
resolver
ensp
ENSP00000511882
resolver
enst
ENST00000342620
resolver
enst
ENST00000620489
resolver
enst
ENST00000695401
resolver
genesymbol
RGS3
resolver
hgnc
HGNC:9999
resolver
uniprot
A0A087WUY2
resolver
uniprot
A0A8Q3WKG2
resolver
uniprot
A6NHA0
resolver
uniprot
A8K0V1
resolver
uniprot
B3KUB2
resolver
uniprot
B3KVT7
resolver
uniprot
B3KWG8
resolver
uniprot
H7BXY1
resolver
uniprot
Q53GP3
resolver
uniprot
Q5VXB8
resolver
uniprot
Q5VXC1
resolver
uniprot
Q5VZ05
resolver
uniprot
Q5VZ06
resolver
uniprot
Q6ZRM5
resolver
uniprot
Q8IUQ1
resolver
uniprot
Q8NC47
resolver
uniprot
Q8NFN4
resolver
uniprot
Q8NFN5
resolver
uniprot
Q8NFN6
resolver
uniprot
Q8TD59
resolver
uniprot
Q8TD68
resolver
uniprot
Q8WV02
resolver
uniprot
Q8WXA0
resolver
uniprot_entry
A0A087WUY2_HUMAN
resolver
uniprot_entry
A0A8Q3WKG2_HUMAN
resolver
uniprot_entry
B3KVT7_HUMAN
resolver
uniprot_entry
B3KWG8_HUMAN
resolver
uniprot_entry
H7BXY1_HUMAN
resolver
uniprot_entry
Q53GP3_HUMAN
resolver
uniprot_entry
RGS3_HUMAN
resolver
uniprot_sec
A6NHA0
resolver
uniprot_sec
A8K0V1
resolver
uniprot_sec
B3KUB2
resolver
uniprot_sec
Q5VXB8
resolver
uniprot_sec
Q5VXC1
resolver
uniprot_sec
Q5VZ05
resolver
uniprot_sec
Q5VZ06
resolver
uniprot_sec
Q6ZRM5
resolver
uniprot_sec
Q8IUQ1
resolver
uniprot_sec
Q8NC47
resolver
uniprot_sec
Q8NFN4
resolver
uniprot_sec
Q8NFN5
resolver
uniprot_sec
Q8NFN6
resolver
uniprot_sec
Q8TD59
resolver
uniprot_sec
Q8TD68
resolver
uniprot_sec
Q8WV02
resolver
uniprot_sec
Q8WXA0
resolver
amino_acid_sequence
MPVIPALWEVEMGRSQGQEIETILANRSHSDSTPLPNFLSGSHRPECCTCRLLTASGAQDSLPFGRRLYSGPWRSCEEVCHVSVLSVLSTSCGLSLSLPIFPGWMEWLSPDIALPRRDEWTQTSPARKRITHAKVQGAGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLIPEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGPDGGVLRRASCKSTHDLQSPPNKREKNCTHGVQARPEQRHSCHLVCDSSDGLLLGGWERYTEVAKRGGQHTLPALSRATAPTDPNYIILAPLNPGSQLLRPVYQEDTIPEESGSPSKGKSYTGLGKKSRLMKTVQTMKGHGNYQNCPVVRPHATHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKAAEVTLFAYSDLLLFTKEDEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAASPPDSKMFETEADEKREMALEEGKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLPPCQDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQGCSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQNSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSMHHLSLFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNESPGAPPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSPPL
uniprot
proteins
function
FUNCTION: Down-regulates signaling from heterotrimeric G proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G protein-mediated release of inositol phosphates and activation of MAP kinases. {ECO:0000269|PubMed:10749886, ECO:0000269|PubMed:11294858, ECO:0000269|PubMed:8602223, ECO:0000269|PubMed:9858594}.
uniprot
proteins
mass_dalton
132336
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by cyclic GMP-dependent protein kinase. {ECO:0000250}.; PTM: ISGylated. {ECO:0000305|PubMed:16884686}.
uniprot
proteins
pubmed
10749886
uniprot
proteins
pubmed
11294858
uniprot
proteins
pubmed
12036301
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16884686
uniprot
proteins
pubmed
17487921
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24129315
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8602223
uniprot
proteins
pubmed
9858594
uniprot
proteins
sequence_length
1198
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:9858594}. Nucleus {ECO:0000269|PubMed:10749886}. Cell membrane {ECO:0000269|PubMed:9858594}; Peripheral membrane protein {ECO:0000269|PubMed:9858594}. Note=Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594). Short isoforms are nuclear (PubMed:10749886).
uniprot
proteins