Tcf7l1
entrez
21415
canonical
uniprot
Q9Z1J1
canonical
ensembl
ENSMUSG00000055799
resolver
ensp
ENSMUSP00000069403
resolver
ensp
ENSMUSP00000109687
resolver
enst
ENSMUST00000069536
resolver
enst
ENSMUST00000114053
resolver
genesymbol
Tcf7l1
resolver
genesymbol_syn
Tcf3
resolver
uniprot
A1A549
resolver
uniprot
A1A550
resolver
uniprot
F6WGY2
resolver
uniprot
F6XXN7
resolver
uniprot
O70450
resolver
uniprot
O70573
resolver
uniprot_entry
A1A549_MOUSE
resolver
uniprot_entry
A1A550_MOUSE
resolver
uniprot_entry
F6WGY2_MOUSE
resolver
uniprot_entry
F6XXN7_MOUSE
resolver
uniprot_entry
TF7L1_MOUSE
resolver
uniprot_sec
O70450
resolver
uniprot_sec
O70573
resolver
amino_acid_sequence
MPQLGGGRGGAGGGGGGSGAGATSGGDDLGANDELIPFQDEGGEEQEPSSDTASAQRDLDEVKSSLVNESENQSSSSDSEAERRPQPARDAFQKPRDYFAEVRRPQDGAFFKGGAYPGYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNDHFSPASPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAAPSLSPAVSAKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHAQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQIQEAEGALASKSKKPCIQYLPPEKPCDSPASSHGSALDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQLALHSAAFLSAKAAASNSSQMGSQPPLLSRPLPLGSMPAALLTSPPTFPATLHAHQALPVLQAQPLSLVTKSAH
uniprot
proteins
function
FUNCTION: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. {ECO:0000269|PubMed:11445543}.
uniprot
proteins
mass_dalton
62298
uniprot
proteins
mutagenesis
MUTAGEN 383; /note="L->P: Abolishes DNA-binding and transactivator/repressor activity; when associated with I-407."; /evidence="ECO:0000269|PubMed:11445543"; MUTAGEN 407; /note="P->I: Abolishes DNA-binding and transactivator/repressor activity; when associated with P-383."; /evidence="ECO:0000269|PubMed:11445543
uniprot
proteins
protein_family
TCF/LEF family
uniprot
proteins
pubmed
10498690
uniprot
proteins
pubmed
11445543
uniprot
proteins
pubmed
9488439
uniprot
proteins
sequence_length
584
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins