Rbks
entrez
71336
canonical
uniprot
Q8R1Q9
canonical
ensembl
ENSMUSG00000029136
resolver
ensp
ENSMUSP00000031018
resolver
ensp
ENSMUSP00000249140
resolver
ensp
ENSMUSP00000249148
resolver
ensp
ENSMUSP00000354780
resolver
enst
ENSMUST00000031018
resolver
genesymbol
Rbks
resolver
genesymbol_syn
Rbsk
resolver
uniprot_entry
RBSK_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity. Competitively inhibited by phosphonoacetic acid, etidronate, 2-carboxethylphosphonic acid, N-(phosphonomethyl)glycine, N-(phosphonomethyl)iminodiacetic acid and clodronate (By similarity). {ECO:0000250|UniProtKB:Q9H477, ECO:0000255|HAMAP-Rule:MF_03215}.
uniprot
proteins
amino_acid_sequence
MAACGEPGRPWQEEEAAAVVVVGSCMTDLVSLTSRLPKTGETIHGHEFFIGFGGKGANQCVQAARLGAKAAIVCKVGNDSFGNDYIENLKQNHISTEFTYQTRDAATGTASIIVNNEGQNIIVIVAGANLFLNSEDLKKAASVISRAKVMICQLEISPAASLEALTMARRSGVKTLFNPAPAMADLDPQFYTLSSIFCCNESEAEILTGHAVSDPTTAGKAAMILLERGCQVVVITLGASGCVILSQAEPVPKHIPTEAVKAVDTTGAGDSFVGALAFYLAYYPNLSLEEMLKRSNFIAAVSVQATGTQSSYPYKKDLPLALF
uniprot
proteins
ec_number
2.7.1.15
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. {ECO:0000255|HAMAP-Rule:MF_03215}.
uniprot
proteins
mass_dalton
34119
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2. {ECO:0000255|HAMAP-Rule:MF_03215}.
uniprot
proteins
protein_family
Carbohydrate kinase PfkB family
uniprot
proteins
protein_family
Ribokinase subfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
323
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03215}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03215}.
uniprot
proteins