Cd276
entrez
102657
canonical
uniprot
Q8VE98
canonical
ensembl
ENSMUSG00000035914
resolver
ensp
ENSMUSP00000042681
resolver
ensp
ENSMUSP00000129418
resolver
ensp
ENSMUSP00000193289
resolver
ensp
ENSMUSP00000193293
resolver
ensp
ENSMUSP00000193297
resolver
enst
ENSMUST00000039788
resolver
enst
ENSMUST00000165365
resolver
genesymbol
Cd276
resolver
genesymbol_syn
B7h3
resolver
uniprot
A6MDC5
resolver
uniprot_entry
A6MDC5_MOUSE
resolver
uniprot_entry
CD276_MOUSE
resolver
amino_acid_sequence
MLRGWGGPSVGVCVRTALGVLCLCLTGAVEVQVSEDPVVALVDTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYSNRTALFPDLLVQGNASLRLQRVRVTDEGSYTCFVSIQDFDSAAVSLQVAAPYSKPSMTLEPNKDLRPGNMVTITCSSYQGYPEAEVFWKDGQGVPLTGNVTTSQMANERGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPLTFPPEALWVTVGLSVCLVVLLVALAFVCWRKIKQSCEEENAGAEDQDGDGEGSKTALRPLKPSENKEDDGQEIA
uniprot
proteins
function
FUNCTION: Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. {ECO:0000269|PubMed:12055244, ECO:0000269|PubMed:12925852, ECO:0000269|PubMed:12939639, ECO:0000269|PubMed:15294965, ECO:0000269|PubMed:15682454}.
uniprot
proteins
mass_dalton
34001
uniprot
proteins
protein_family
BTN/MOG family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12055244
uniprot
proteins
pubmed
12906861
uniprot
proteins
pubmed
12925852
uniprot
proteins
pubmed
12939639
uniprot
proteins
pubmed
15294965
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15682454
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19349973
uniprot
proteins
pubmed
19656770
uniprot
proteins
sequence_length
316
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 249..269; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins