Dnajb6
entrez
23950
canonical
uniprot
O54946
canonical
ensembl
ENSMUSG00000029131
resolver
ensp
ENSMUSP00000008733
resolver
ensp
ENSMUSP00000012734
resolver
ensp
ENSMUSP00000110488
resolver
ensp
ENSMUSP00000262147
resolver
ensp
ENSMUSP00000262155
resolver
ensp
ENSMUSP00000362854
resolver
enst
ENSMUST00000012734
resolver
genesymbol
Dnajb6
resolver
genesymbol_syn
Hsj2
resolver
genesymbol_syn
Mrj
resolver
uniprot
G3X8S5
resolver
uniprot
Q3TE94
resolver
uniprot
Q3U6L0
resolver
uniprot
Q3UNJ5
resolver
uniprot
Q3UYT7
resolver
uniprot
Q99LA5
resolver
uniprot
Q9QYI9
resolver
uniprot_entry
DNJB6_MOUSE
resolver
uniprot_entry
G3X8S5_MOUSE
resolver
uniprot_sec
Q3TE94
resolver
uniprot_sec
Q3U6L0
resolver
uniprot_sec
Q3UNJ5
resolver
uniprot_sec
Q3UYT7
resolver
uniprot_sec
Q99LA5
resolver
uniprot_sec
Q9QYI9
resolver
amino_acid_sequence
MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGIHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGNRSRGAGSFFSTFSGFPSFGSGFPAFDTGFTPFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQPTPALAPGPAPAPVRVPSQARPLAPTPAPTPAPTPAPAPAQTPAPSVSTRPQKPPRPAPTAKLGSKSNWEDDEQDRQRVPGNWDAPMTSAGLKEGGKRKKQKQKEDLKKKKSTKGNH
uniprot
proteins
function
FUNCTION: Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed:18373498). Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity (By similarity). {ECO:0000250|UniProtKB:O75190, ECO:0000269|PubMed:18373498}.
uniprot
proteins
mass_dalton
39807
uniprot
proteins
pubmed
11147971
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
18163532
uniprot
proteins
pubmed
18373498
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
24129315
uniprot
proteins
sequence_length
365
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O75190}. Nucleus {ECO:0000250|UniProtKB:O75190}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:O75190}.
uniprot
proteins