CLDN25
entrez
644672
canonical
uniprot
C9JDP6
canonical
ensembl
ENSG00000228607
resolver
ensp
ENSP00000396304
resolver
enst
ENST00000453129
resolver
genesymbol
CLDN25
resolver
hgnc
HGNC:37218
resolver
uniprot_entry
CLD25_HUMAN
resolver
amino_acid_sequence
MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEVATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIFSACLGKEDVPFPLMAGPTVPLSCAPVEESDGSFHLMLRPRNLVI
uniprot
proteins
function
FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. {ECO:0000250}.
uniprot
proteins
mass_dalton
25394
uniprot
proteins
protein_family
Claudin family
uniprot
proteins
pubmed
16554811
uniprot
proteins
pubmed
30734065
uniprot
proteins
sequence_length
229
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, tight junction {ECO:0000269|PubMed:30734065}. Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 11..31; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 82..102; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 125..145; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 165..185; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins