TXNDC12
entrez
51060
canonical
uniprot
O95881
canonical
ensembl
ENSG00000117862
resolver
ensp
ENSP00000360688
resolver
ensp
ENSP00000520430
resolver
enst
ENST00000371626
resolver
enst
ENST00000715260
resolver
genesymbol
TXNDC12
resolver
genesymbol_syn
TLP19
resolver
hgnc
HGNC:24626
resolver
uniprot
B3KQS0
resolver
uniprot
Q5T1T4
resolver
uniprot
Q96H50
resolver
uniprot_entry
TXD12_HUMAN
resolver
uniprot_sec
B3KQS0
resolver
uniprot_sec
Q5T1T4
resolver
uniprot_sec
Q96H50
resolver
amino_acid_sequence
METRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDPSGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL
uniprot
proteins
ec_number
1.8.4.2
uniprot
proteins
function
FUNCTION: Protein-disulfide reductase of the endoplasmic reticulum that promotes disulfide bond formation in client proteins through its thiol-disulfide oxidase activity. {ECO:0000269|PubMed:12761212}.
uniprot
proteins
mass_dalton
19206
uniprot
proteins
mutagenesis
MUTAGEN 66; /note="C->S: Loss of protein-disulfide reductase (glutathione) activity. Loss of the formation of disulfide bonds in substrate."; /evidence="ECO:0000269|PubMed:12761212"; MUTAGEN 69; /note="C->S: Loss of protein-disulfide reductase (glutathione) activity. Loss of the formation of disulfide bonds in substrate."; /evidence="ECO:0000269|PubMed:12761212
uniprot
proteins
pubmed
12761212
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14557066
uniprot
proteins
pubmed
15340161
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
19361226
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
172
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:12761212}.
uniprot
proteins