ANO4
entrez
121601
canonical
uniprot
Q32M45
canonical
ensembl
ENSG00000151572
resolver
ensembl
ENSG00000262139
resolver
ensp
ENSP00000376703
resolver
ensp
ENSP00000376705
resolver
ensp
ENSP00000469449
resolver
ensp
ENSP00000470039
resolver
ensp
ENSP00000471431
resolver
ensp
ENSP00000494481
resolver
ensp
ENSP00000522739
resolver
ensp
ENSP00000522744
resolver
ensp
ENSP00000592809
resolver
ensp
ENSP00000592810
resolver
enst
ENST00000570509
resolver
enst
ENST00000573650
resolver
enst
ENST00000575847
resolver
enst
ENST00000644049
resolver
genesymbol
ANO4
resolver
genesymbol_syn
TMEM16D
resolver
hgnc
HGNC:23837
resolver
uniprot
A0A2R8Y532
resolver
uniprot
B7Z9Z0
resolver
uniprot
Q8NAJ0
resolver
uniprot
Q8NB39
resolver
uniprot
Q8NB53
resolver
uniprot_entry
A0A2R8Y532_HUMAN
resolver
uniprot_entry
ANO4_HUMAN
resolver
uniprot_entry
B7Z9Z0_HUMAN
resolver
uniprot_sec
Q8NAJ0
resolver
uniprot_sec
Q8NB39
resolver
uniprot_sec
Q8NB53
resolver
amino_acid_sequence
MEASSSGITNGKTKVFHPEGGVDLQGYQLDMQILPDGPKSDVDFSEILNAIQEMAKDVNILFDELEAVSSPCKDDDSLLHPGNLTSTSDDASRLEAGGETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKAHHNEWP
uniprot
proteins
function
FUNCTION: Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). {ECO:0000250|UniProtKB:Q8C5H1}.
uniprot
proteins
mass_dalton
111462
uniprot
proteins
protein_family
Anoctamin family
uniprot
proteins
pubmed
12739008
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21607626
uniprot
proteins
pubmed
21642943
uniprot
proteins
pubmed
22302790
uniprot
proteins
pubmed
22946059
uniprot
proteins
sequence_length
955
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:22946059}; Multi-pass membrane protein {ECO:0000269|PubMed:22946059}. Note=Shows an intracellular localization. {ECO:0000250|UniProtKB:Q8C5H1}.
uniprot
proteins
transmembrane_region
TRANSMEM 353..373; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 425..445; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 506..526; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 548..568; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 596..616; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 716..736; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 769..789; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 886..906; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins