Cntn1
entrez
12805
canonical
uniprot
P12960
canonical
ensembl
ENSMUSG00000055022
resolver
ensp
ENSMUSP00000000109
resolver
ensp
ENSMUSP00000067842
resolver
ensp
ENSMUSP00000133063
resolver
ensp
ENSMUSP00000291912
resolver
ensp
ENSMUSP00000291923
resolver
enst
ENSMUST00000000109
resolver
enst
ENSMUST00000068378
resolver
enst
ENSMUST00000169825
resolver
genesymbol
Cntn1
resolver
uniprot
Q6NXV7
resolver
uniprot
Q8BR42
resolver
uniprot
Q8C6A0
resolver
uniprot_entry
CNTN1_MOUSE
resolver
uniprot_sec
Q6NXV7
resolver
uniprot_sec
Q8BR42
resolver
uniprot_sec
Q8C6A0
resolver
amino_acid_sequence
MKMPLLVSHLLLISLTSCLGDFTWHRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTNDRYSMVGGNLVINNPDKQKDAGVYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVKVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVESSDRGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDIYTMMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGLYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCIATGKPIPTIRWLKNGYSYHKGELRLYDVTFENAGMYQCIAENAYGSIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITNPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKEITHIHYQRNFMLDANGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAVDLIPWMEYEFRVVATNTLGTGEPSIPSNRIKTDGAAPNVAPSDVGGGGGTNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMTPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWKHVLEKIVESYQIRYWAGHDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKILYRPDGQHDGKLFSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGVSTLSSSLLSLLLPSLGFLVYSEF
uniprot
proteins
function
FUNCTION: Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth. {ECO:0000269|PubMed:11395001, ECO:0000269|PubMed:14567914, ECO:0000269|PubMed:7678967}.
uniprot
proteins
mass_dalton
113388
uniprot
proteins
protein_family
Contactin family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
11395001
uniprot
proteins
pubmed
11564762
uniprot
proteins
pubmed
14567914
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20133774
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2474555
uniprot
proteins
pubmed
31112734
uniprot
proteins
pubmed
34272044
uniprot
proteins
pubmed
7678967
uniprot
proteins
sequence_length
1020
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
uniprot
proteins