PPP2R2D
entrez
55844
canonical
uniprot
Q66LE6
canonical
ensembl
ENSG00000175470
resolver
ensp
ENSP00000399970
resolver
ensp
ENSP00000789365
resolver
enst
ENST00000455566
resolver
genesymbol
PPP2R2D
resolver
genesymbol_syn
KIAA1541
resolver
hgnc
HGNC:23732
resolver
uniprot
A8KAK0
resolver
uniprot
Q5SQJ2
resolver
uniprot
Q6IN90
resolver
uniprot
Q9P1Y7
resolver
uniprot_entry
2ABD_HUMAN
resolver
uniprot_entry
Q6IN90_HUMAN
resolver
uniprot_sec
A8KAK0
resolver
uniprot_sec
Q5SQJ2
resolver
uniprot_sec
Q9P1Y7
resolver
amino_acid_sequence
MAGAGGGGCPAGGNDFQWCFSQVKGAIDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKSRPHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMESRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRDTRRDVTLEASRESSKPRASLKPRKVCTGGKRRKDEISVDSLDFNKKILHTAWHPVDNVIAVAATNNLYIFQDKIN
uniprot
proteins
function
FUNCTION: Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67 (By similarity). The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis (By similarity). {ECO:0000250|UniProtKB:Q7ZX64, ECO:0000250|UniProtKB:Q925E7}.
uniprot
proteins
mass_dalton
52042
uniprot
proteins
protein_family
Phosphatase 2A regulatory subunit B family
uniprot
proteins
pubmed
10819331
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
25816751
uniprot
proteins
sequence_length
453
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P56932}.
uniprot
proteins