Rpain
entrez
287463
canonical
uniprot
Q4G2Y1
canonical
ensembl
ENSRNOG00000006913
resolver
ensembl
ENSRNOG00055032487
resolver
ensembl
ENSRNOG00060025334
resolver
ensembl
ENSRNOG00065029685
resolver
ensp
ENSRNOP00000097917
resolver
genesymbol
Rpain
resolver
genesymbol_syn
Rip
resolver
uniprot_entry
RIP_RAT
resolver
amino_acid_sequence
MAESSGSPHRLLYKQVGSPPWKETFRQGCLERMRNSRHKLLNRYRQAAGSTLGTASDRLLVQEVMEEEWNSLQSVENCPEALLQLELPLNLAVLQDIEQELWNEEKSIISEYEKGLQFDESCLNSMLAEWEANPLICPVCIKYNLRIMNSVVTCPCGLHIPSHSTDLTEQKLRACLEGNVNEHSAHCPHIPEFSVTGGTEEKPSLLMSCLACDTWAVIL
uniprot
proteins
function
FUNCTION: Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Sumoylation mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
24710
uniprot
proteins
post_translational_modification
PTM: Sumoylated; required for localization in the nuclear PML body and transport of RPA complex in PML body. Upon UV irradiation and during S phase, it is desumoylated, releasing RPA complex that is translocated to sites of DNA damage. Sumoylation takes place at different Lys residues (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15277470
uniprot
proteins
pubmed
16008515
uniprot
proteins
sequence_length
219
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins