Hmgcll1
entrez
367112
canonical
uniprot
D4A5C3
canonical
ensembl
ENSRNOG00000011193
resolver
ensembl
ENSRNOG00055007526
resolver
ensembl
ENSRNOG00060018465
resolver
ensembl
ENSRNOG00065017142
resolver
ensp
ENSRNOP00000014927
resolver
ensp
ENSRNOP00000112407
resolver
ensp
ENSRNOP00055009975
resolver
ensp
ENSRNOP00060025825
resolver
ensp
ENSRNOP00065022679
resolver
enst
ENSRNOT00000014926
resolver
enst
ENSRNOT00000132426
resolver
enst
ENSRNOT00055012557
resolver
enst
ENSRNOT00060031794
resolver
enst
ENSRNOT00065028631
resolver
genesymbol
Hmgcll1
resolver
uniprot
A0ABK0M2D4
resolver
uniprot_entry
A0ABK0M2D4_RAT
resolver
uniprot_entry
HMGC2_RAT
resolver
amino_acid_sequence
MGNLPSAAKHCLNYQQLLREHLWSGESVAGALDPAQEASQLSGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIEFINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMGGIHQYPGVRYPVLVPNLQGLQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFEQVISSARHMNIPVRGYVSCALGCPYEGSIMPQKVTEVSKRLYSMGCYEISLGDTVGVGTPGSMKTMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGMGLNTGVDLHKVMEAGDFICKAVNKTTNSKVAQASFKARLE
uniprot
proteins
ec_number
4.1.3.4
uniprot
proteins
function
FUNCTION: Non-mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues. {ECO:0000250}.
uniprot
proteins
mass_dalton
36549
uniprot
proteins
pathway_participation
PATHWAY: Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.
uniprot
proteins
protein_family
HMG-CoA lyase family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
22865860
uniprot
proteins
sequence_length
343
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
uniprot
proteins