Nop56
entrez
67134
canonical
uniprot
Q9D6Z1
canonical
ensembl
ENSMUSG00000027405
resolver
ensp
ENSMUSP00000099487
resolver
ensp
ENSMUSP00000238845
resolver
enst
ENSMUST00000103198
resolver
genesymbol
Nop56
resolver
genesymbol_syn
Nol5a
resolver
uniprot
Q3UD45
resolver
uniprot
Q8BVL1
resolver
uniprot
Q8VDT2
resolver
uniprot
Q99LT8
resolver
uniprot
Q9CT15
resolver
uniprot_entry
NOP56_MOUSE
resolver
uniprot_sec
Q3UD45
resolver
uniprot_sec
Q8BVL1
resolver
uniprot_sec
Q8VDT2
resolver
uniprot_sec
Q99LT8
resolver
uniprot_sec
Q9CT15
resolver
amino_acid_sequence
MVLLHVLFEHAVGYALLALKEVEEISLLLPQVEECVLNLGKFHNVVRLVAFCPFSSSQVALENANAVSEGVVHEDLRLLLETYLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIVNDNATYCRLAQFIGNRRELNEEKLEKLEEITMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAVVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSTPEECEEVNEKSKKKKKLKPQENGMEDPPVSLPKSKKKKAPKEELASDLEEMATSSAKRKKSSPKEEVASEPEEAASPTTPKKKRKFSEEPEVAANFTKSSTKKKKKSQKAQED
uniprot
proteins
function
FUNCTION: Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs). {ECO:0000250|UniProtKB:O00567}.
uniprot
proteins
mass_dalton
64464
uniprot
proteins
protein_family
NOP5/NOP56 family
uniprot
proteins
pubmed
10864044
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
18630941
uniprot
proteins
pubmed
19131326
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21683323
uniprot
proteins
pubmed
23806337
uniprot
proteins
sequence_length
580
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:O00567}. Cytoplasm {ECO:0000269|PubMed:21683323}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:O00567}.
uniprot
proteins