Cnksr3
entrez
215748
canonical
uniprot
Q8BMA3
canonical
ensembl
ENSMUSG00000015202
resolver
ensp
ENSMUSP00000015346
resolver
genesymbol
Cnksr3
resolver
uniprot
Q3UDS2
resolver
uniprot
Q8K2K0
resolver
uniprot_entry
CNKR3_MOUSE
resolver
uniprot_sec
Q3UDS2
resolver
uniprot_sec
Q8K2K0
resolver
amino_acid_sequence
MEPVTKWSPKQVVDWTRGLDDCLQPYVHKFEREKIDGEQLLKISHQDLEELGVTRIGHQELVLEAVDLLCALNYGLETDTMKNLVLKLRASSHNLQNYISSRRKSPAYDGNTSRKPPNEFLTSVVELIGAAKALLAWLDRAPFTGITDLSVTKNKIIQLCLDLTTAVQKDCLIAEMEDKVLNVVKVLNGICDKTMRSTTDPVMSQCACLEEVHLPNVRPGEGLGMYIKSTYDGLHVITGTTENSPADRSQKIHAGDEVIQVNRQTVVGWQLKNLVRKLRENPTGVVLLLKKRPTGSFSFTPAPLKNLRWKPPLVQTSPPPTTTQSPESTMDASLKKEKPAILDLYIPPPPAVPYSPRDENVSFGYRGHSKSKQPLPVRKGSESPNSFLDQESQRRRFTIADSDQLPGYSVETNVLPTKMRGKTPSYGKPRPLSMPADGNWMGIVDPFAKPRGNGRKGEDALCRYFSNERITPITEESASPMYRFSRPLTERHLVRGADYIRGSRCYINSDLHSSATIPFQEEGSKKKSASSSAKASSGEPSLLVSWLTRLKLLTH
uniprot
proteins
function
FUNCTION: Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC). {ECO:0000269|PubMed:19567370, ECO:0000269|PubMed:22851176}.
uniprot
proteins
mass_dalton
61870
uniprot
proteins
protein_family
CNKSR family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19567370
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22851176
uniprot
proteins
sequence_length
555
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22851176}. Apical cell membrane {ECO:0000269|PubMed:22851176}; Peripheral membrane protein {ECO:0000269|PubMed:22851176}.
uniprot
proteins