ARMCX3
entrez
51566
canonical
uniprot
Q9UH62
canonical
ensembl
ENSG00000102401
resolver
ensp
ENSP00000340672
resolver
ensp
ENSP00000439032
resolver
ensp
ENSP00000454483
resolver
ensp
ENSP00000562703
resolver
ensp
ENSP00000562704
resolver
ensp
ENSP00000562705
resolver
ensp
ENSP00000562706
resolver
ensp
ENSP00000562707
resolver
ensp
ENSP00000562708
resolver
ensp
ENSP00000562709
resolver
ensp
ENSP00000562710
resolver
ensp
ENSP00000562711
resolver
ensp
ENSP00000562712
resolver
ensp
ENSP00000562713
resolver
ensp
ENSP00000562714
resolver
ensp
ENSP00000562715
resolver
ensp
ENSP00000562716
resolver
ensp
ENSP00000562717
resolver
ensp
ENSP00000609787
resolver
ensp
ENSP00000609788
resolver
ensp
ENSP00000609789
resolver
ensp
ENSP00000630695
resolver
ensp
ENSP00000630696
resolver
ensp
ENSP00000630697
resolver
enst
ENST00000341189
resolver
enst
ENST00000471229
resolver
enst
ENST00000537169
resolver
enst
ENST00000892644
resolver
enst
ENST00000892645
resolver
enst
ENST00000892646
resolver
enst
ENST00000892647
resolver
enst
ENST00000892648
resolver
enst
ENST00000892649
resolver
enst
ENST00000892650
resolver
enst
ENST00000892651
resolver
enst
ENST00000892652
resolver
enst
ENST00000892653
resolver
enst
ENST00000892654
resolver
enst
ENST00000892655
resolver
enst
ENST00000892656
resolver
enst
ENST00000892657
resolver
enst
ENST00000892658
resolver
enst
ENST00000939728
resolver
enst
ENST00000939729
resolver
enst
ENST00000939730
resolver
enst
ENST00000960636
resolver
enst
ENST00000960637
resolver
enst
ENST00000960638
resolver
genesymbol
ARMCX3
resolver
genesymbol_syn
ALEX3
resolver
hgnc
HGNC:24065
resolver
uniprot
Q53HC6
resolver
uniprot
Q7LCF5
resolver
uniprot
Q9NPE4
resolver
uniprot_entry
ARMX3_HUMAN
resolver
uniprot_sec
Q53HC6
resolver
uniprot_sec
Q7LCF5
resolver
uniprot_sec
Q9NPE4
resolver
amino_acid_sequence
MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDAGDCSGARYNDWSDDDDDSNESKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKENKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESHHDFLVKVKVGKFMAKLAEHMFPKSQE
uniprot
proteins
function
FUNCTION: Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters. {ECO:0000250|UniProtKB:Q8BHS6}.
uniprot
proteins
mass_dalton
42501
uniprot
proteins
protein_family
Eutherian X-chromosome-specific Armcx family
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
11162520
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18318008
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
sequence_length
379
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000250|UniProtKB:Q8BHS6}. Nucleus {ECO:0000250|UniProtKB:Q8BHS6}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..29; /note="Helical; Signal-anchor"; /evidence="ECO:0000255
uniprot
proteins