MYH10
entrez
4628
canonical
uniprot
P35580
canonical
ensembl
ENSG00000133026
resolver
ensp
ENSP00000269243
resolver
ensp
ENSP00000353590
resolver
ensp
ENSP00000369315
resolver
ensp
ENSP00000509695
resolver
ensp
ENSP00000510471
resolver
ensp
ENSP00000586111
resolver
ensp
ENSP00000586115
resolver
ensp
ENSP00000625242
resolver
enst
ENST00000684843
resolver
enst
ENST00000692526
resolver
enst
ENST00000916052
resolver
enst
ENST00000916056
resolver
enst
ENST00000955183
resolver
genesymbol
MYH10
resolver
hgnc
HGNC:7568
resolver
uniprot
A0A8I5KZ38
resolver
uniprot
B2RWP9
resolver
uniprot
D3DTS1
resolver
uniprot
F8VTL3
resolver
uniprot
G1UI33
resolver
uniprot
Q12989
resolver
uniprot
Q149N3
resolver
uniprot
Q149N4
resolver
uniprot
Q16087
resolver
uniprot
Q4LE45
resolver
uniprot
Q6PK16
resolver
uniprot
Q9BWG0
resolver
uniprot_entry
A0A8I5KZ38_HUMAN
resolver
uniprot_entry
G1UI33_HUMAN
resolver
uniprot_entry
MYH10_HUMAN
resolver
uniprot_sec
B2RWP9
resolver
uniprot_sec
D3DTS1
resolver
uniprot_sec
F8VTL3
resolver
uniprot_sec
Q12989
resolver
uniprot_sec
Q149N3
resolver
uniprot_sec
Q149N4
resolver
uniprot_sec
Q16087
resolver
uniprot_sec
Q4LE45
resolver
uniprot_sec
Q6PK16
resolver
uniprot_sec
Q9BWG0
resolver
amino_acid_sequence
MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQSE
uniprot
proteins
disease_involvement
DISEASE: Note=Associated with severe intellectual disability, microcephaly, and feeding difficulties as well as cerebral atrophy. {ECO:0000269|PubMed:25003005, ECO:0000269|PubMed:25356899}.
uniprot
proteins
function
FUNCTION: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. {ECO:0000269|PubMed:20052411, ECO:0000269|PubMed:20603131}.; FUNCTION: (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1 envelope glycoprotein B. {ECO:0000305|PubMed:25428876, ECO:0000305|PubMed:39048823}.
uniprot
proteins
mass_dalton
228999
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by ABL2. {ECO:0000250}.
uniprot
proteins
protein_family
Myosin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16625196
uniprot
proteins
pubmed
16721066
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17525332
uniprot
proteins
pubmed
18318008
uniprot
proteins
pubmed
1860190
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20052411
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
20603131
uniprot
proteins
pubmed
20682791
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22480440
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25003005
uniprot
proteins
pubmed
25356899
uniprot
proteins
pubmed
25428876
uniprot
proteins
pubmed
28345668
uniprot
proteins
pubmed
39048823
uniprot
proteins
pubmed
7499478
uniprot
proteins
pubmed
7782316
uniprot
proteins
pubmed
7916668
uniprot
proteins
pubmed
8690889
uniprot
proteins
sequence_length
1976
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, lamellipodium {ECO:0000269|PubMed:20052411, ECO:0000269|PubMed:22480440}. Note=Colocalizes with MCC at the leading edge of migrating cells.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:25428876}. Note=(Microbial infection) Localizes at the surface of the cell membrane following infection by herpes simplex virus 1/HHV-1,. {ECO:0000305|PubMed:25428876}.
uniprot
proteins