STM7
entrez
8395
canonical
uniprot
O14986
canonical
ensembl
ENSG00000107242
resolver
ensp
ENSP00000265382
resolver
ensp
ENSP00000435778
resolver
ensp
ENSP00000438082
resolver
ensp
ENSP00000555725
resolver
ensp
ENSP00000555732
resolver
ensp
ENSP00000555733
resolver
ensp
ENSP00000555734
resolver
ensp
ENSP00000555736
resolver
ensp
ENSP00000555737
resolver
ensp
ENSP00000619945
resolver
ensp
ENSP00000657563
resolver
ensp
ENSP00000785986
resolver
genesymbol
PIP5K1B
resolver
genesymbol
STM7
resolver
genesymbol_syn
STM7
resolver
hgnc
HGNC:8995
resolver
uniprot
A8K9L9
resolver
uniprot
B4DIG7
resolver
uniprot
P78518
resolver
uniprot
P78519
resolver
uniprot
Q5T5K6
resolver
uniprot
Q5T5K8
resolver
uniprot
Q5T5K9
resolver
uniprot
Q5VZ00
resolver
uniprot
Q7KYT5
resolver
uniprot
Q7KYT6
resolver
uniprot
Q8NHQ5
resolver
uniprot
Q92749
resolver
uniprot_entry
PI51B_HUMAN
resolver
uniprot_entry
Q7KYT6_HUMAN
resolver
uniprot_sec
A8K9L9
resolver
uniprot_sec
B4DIG7
resolver
uniprot_sec
P78518
resolver
uniprot_sec
P78519
resolver
uniprot_sec
Q5T5K6
resolver
uniprot_sec
Q5T5K8
resolver
uniprot_sec
Q5T5K9
resolver
uniprot_sec
Q5VZ00
resolver
uniprot_sec
Q7KYT5
resolver
uniprot_sec
Q8NHQ5
resolver
uniprot_sec
Q92749
resolver
amino_acid_sequence
MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEIVSSISQEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVNEHYPHDRPTLYSNSKGLPSSSTFTLEEGTIYLTAEPNTLEVQDDNASVLDVYL
uniprot
proteins
ec_number
2.7.1.68
uniprot
proteins
function
FUNCTION: Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4)P/PI4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2), a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility (By similarity). PtdIns(4,5)P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3), diacylglycerol (DAG) or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3/PIP3) (By similarity). Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of phospholipase PLD2. Together with PIP5K1A, is required, after stimulation by G protein-coupled receptors, for the synthesis of IP3 that will induce stable platelet adhesion (By similarity). {ECO:0000250|UniProtKB:P70181, ECO:0000250|UniProtKB:Q99755}.
uniprot
proteins
mass_dalton
61036
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
8841185
uniprot
proteins
pubmed
8955136
uniprot
proteins
pubmed
9177790
uniprot
proteins
sequence_length
540
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P70181}. Cell membrane {ECO:0000250|UniProtKB:P70181}. Endomembrane system. Note=Associated with membranes. {ECO:0000250}.
uniprot
proteins