Lsm8
entrez
76522
canonical
uniprot
Q6ZWM4
canonical
ensembl
ENSMUSG00000044155
resolver
ensp
ENSMUSP00000057238
resolver
enst
ENSMUST00000056398
resolver
genesymbol
Lsm8
resolver
uniprot
Q3TIX3
resolver
uniprot_entry
LSM8_MOUSE
resolver
uniprot_sec
Q3TIX3
resolver
amino_acid_sequence
MTSALENYINRTVAVITSDGRMIVGTLKGFDQTINLILDESHERVFSSSQGVEQVVLGLYIVRGDNVAVIGEIDEETDSALDLGNIRAEPLNSVAH
uniprot
proteins
function
FUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. {ECO:0000250|UniProtKB:O95777}.
uniprot
proteins
mass_dalton
10403
uniprot
proteins
protein_family
SnRNP Sm proteins family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
96
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O95777}.
uniprot
proteins