Snrpd3
entrez
67332
canonical
uniprot
P62320
canonical
ensembl
ENSMUSG00000020180
resolver
ensp
ENSMUSP00000020397
resolver
enst
ENSMUST00000020397
resolver
genesymbol
Snrpd3
resolver
uniprot
P43331
resolver
uniprot
Q3TV81
resolver
uniprot_entry
SMD3_MOUSE
resolver
uniprot_sec
P43331
resolver
uniprot_sec
Q3TV81
resolver
amino_acid_sequence
MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR
uniprot
proteins
function
FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:19470752). {ECO:0000250|UniProtKB:P62318, ECO:0000269|PubMed:19470752}.
uniprot
proteins
mass_dalton
13916
uniprot
proteins
post_translational_modification
PTM: Methylated on arginine residues by PRMT5 and PRMT7; probable asymmetric dimethylation which is required for assembly and biogenesis of snRNPs. {ECO:0000250|UniProtKB:P62318}.
uniprot
proteins
protein_family
SnRNP core protein family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19470752
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
126
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62318}. Nucleus {ECO:0000269|PubMed:19470752}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000250|UniProtKB:P62318}.
uniprot
proteins