F7
entrez
260320
canonical
uniprot
Q8K3U6
canonical
ensembl
ENSRNOG00000032737
resolver
ensembl
ENSRNOG00055015036
resolver
ensembl
ENSRNOG00060019172
resolver
ensembl
ENSRNOG00065009327
resolver
ensp
ENSRNOP00000038466
resolver
ensp
ENSRNOP00055020988
resolver
ensp
ENSRNOP00060027222
resolver
ensp
ENSRNOP00065011140
resolver
enst
ENSRNOT00000037806
resolver
enst
ENSRNOT00055025721
resolver
enst
ENSRNOT00060033261
resolver
enst
ENSRNOT00065014914
resolver
genesymbol
F7
resolver
uniprot_entry
FA7_RAT
resolver
amino_acid_sequence
MVPQTHGLLLLYFLLQLQGPLGAVVFITQEEAHGVLHRQRRANSLLEELWSSSLERECNEERCSFEEAREIFKSPERTKQFWTIYSDGDQCASNPCQNGGTCQDHLKSYVCFCPLDFEGRNCEKNKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYVLQPDEVSCKPKVEYPCGRIPVVEKRNFSRPQGRIVGGYVCPKGECPWQAVLKFNEALLCGAVLLDTRWIVTAAHCFDKFGKLVNITVVLGEHDFSEKEGTEQVRLVEQVIMPNKYTRGRTDHDIALVRLHRPVTFTDYVVPLCLPERAFSENTLASIRFSRVSGWGQLLDRGATALELMVIEVPRLMTQDCLEHAKHSANTPRITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVKYMDSKLRVGISRVSLL
uniprot
proteins
ec_number
3.4.21.21
uniprot
proteins
function
FUNCTION: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
50399
uniprot
proteins
post_translational_modification
PTM: The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. {ECO:0000250}.; PTM: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. {ECO:0000250}.; PTM: Can be either O-glucosylated or O-xylosylated at Ser-93 by POGLUT1. {ECO:0000250}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
sequence_length
446
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
uniprot
proteins