RSC1A1
entrez
6248
canonical
uniprot
Q92681
canonical
ensembl
ENSG00000215695
resolver
ensp
ENSP00000341963
resolver
enst
ENST00000345034
resolver
genesymbol
RSC1A1
resolver
hgnc
HGNC:10458
resolver
uniprot
B2RBP5
resolver
uniprot_entry
RSCA1_HUMAN
resolver
uniprot_sec
B2RBP5
resolver
amino_acid_sequence
MSSLPTSDGFNHPARSSGQSPDVGNPMSLARSVSASVCPIKPSDSDRIEPKAVKALKASAEFQLNSEKKEHLSLQDLSDHASSADHAPTDQSPAMPMQNSSEEITVAGNLEKSAERSTQGLKFHLHTRQEASLSVTSTRMHEPQMFLGEKDWHPENQNLSQVSDPQQHEEPGNEQYEVAQQKASHDQEYLCNIGDLELPEERQQNQHKIVDLEATMKGNGLPQNVDPPSAKKSIPSSECSGCSNSETFMEIDTAQQSLVTLLNSTGRQNANVKNIGALDLTLDNPLMEVETSKCNPSSEILNDSISTQDLQPPETNVEIPGTNKEYGHYSSPSLCGSCQPSVESAEESCPSITAALKELHELLVVSSKPASENTSEEVICQSETIAEGQTSIKDLSERWTQNEHLTQNEQCPQVSFHQAISVSVETEKLTGTSSDTGREAVENVNFRSLGDGLSTDKEGVPKSRESINKNRSVTVTSAKTSNQLHCTLGVEISPKLLAGEEDALNQTSEQTKSLSSNFILVKDLGQGIQNSVTDRPETRENVCPDASRPLLEYEPPTSHPSSSPAILPPLIFPATDIDRILRAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT
uniprot
proteins
function
FUNCTION: Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network. {ECO:0000269|PubMed:14724758, ECO:0000269|PubMed:16788146, ECO:0000269|PubMed:8836035}.
uniprot
proteins
mass_dalton
66790
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14724758
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
16788146
uniprot
proteins
pubmed
16788147
uniprot
proteins
pubmed
17686765
uniprot
proteins
pubmed
8836035
uniprot
proteins
sequence_length
617
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:16788147}. Nucleus {ECO:0000269|PubMed:16788147}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:16788147}. Note=Localizes at the inner side of the plasma membrane.
uniprot
proteins