Hsf5
entrez
327992
canonical
uniprot
Q5ND04
canonical
ensembl
ENSMUSG00000070345
resolver
ensp
ENSMUSP00000091488
resolver
enst
ENSMUST00000093956
resolver
genesymbol
Hsf5
resolver
genesymbol_syn
Gm739
resolver
uniprot
B2KGG8
resolver
uniprot
Q3TLD8
resolver
uniprot_entry
HSF5_MOUSE
resolver
uniprot_sec
B2KGG8
resolver
uniprot_sec
Q3TLD8
resolver
amino_acid_sequence
MEEALLSTPINPNNFPAKLWRLVNSPRYRSIRWDGRGEGLLIDQPLFEAELLSPPGPGAGGAGGAGSSGGGGGSGVGAAGAEPELFKTTNFTSFIRQLNLYGFRKVVLGGPGAAGPGPGPGAGGPAGDGPLHHFHSPHFRRDQPQLLVHLKRLTSANKAKLAAGLEVPCRPPNRFQRLLITSASASASASTSPLQHQDPPPQPAGPRPEQHGPVAVGQFHRSFRRDNLSPYSYVSTSSHNHSAFPLKGLDRTPIPPRTWQNSLGMHPGQVETSPTFSDKGVPFPVLQRFPTEVTYTLQPSATSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYYPTAVLQCCSPPTHMDALSSCVTPTASSYAHCNYFQNPPMQSSYPVEFLPSNWPCSATDENKKTEVNLEAVFQIVDELHSSPKLEMVKVEPVETQCPSSQANRGQHILPNANSSNPSSTSQASQLEPLTPVGSDITSFVVGTEQAITCSLPQSPEYIYTIHTAQPLENSTMQESATIQQTHVKLKEQLNHNPSPSSVVFVQEGLPFSTPQVDSSIKCQTNPSENILPSEQMGFLISEMGPANKSTKDTGLSTPARYRERRSNSQGKSPDLHLLVDVACKQEHFPKEEELKE
uniprot
proteins
function
FUNCTION: DNA-binding transcription factor that is essential for male fertility, spermatogenesis and meiotic prophase progression in spermatocytes under non-stress conditions (PubMed:38684656). Positvely and negatively regulates gene expression to ensure progression of meiotic prophase beyond pachytene stage in spermatocytes (PubMed:38684656). {ECO:0000269|PubMed:38684656}.
uniprot
proteins
mass_dalton
67316
uniprot
proteins
protein_family
HSF family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
20339383
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
37206036
uniprot
proteins
pubmed
38684656
uniprot
proteins
pubmed
40535264
uniprot
proteins
sequence_length
624
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:38684656}. Chromosome {ECO:0000269|PubMed:38684656}. Note=Expressed primarily in the XY body of pachytene spermatocytes. {ECO:0000269|PubMed:38684656}.
uniprot
proteins