Gfra4
entrez
14588
canonical
uniprot
Q9JJT2
canonical
ensembl
ENSMUSG00000027316
resolver
ensp
ENSMUSP00000028787
resolver
ensp
ENSMUSP00000068357
resolver
ensp
ENSMUSP00000105868
resolver
ensp
ENSMUSP00000105869
resolver
genesymbol
Gfra4
resolver
uniprot
A2AP44
resolver
uniprot
A2AP45
resolver
uniprot
A2AP46
resolver
uniprot
A2AP47
resolver
uniprot
A2AP49
resolver
uniprot
Q8C1V7
resolver
uniprot
Q9JJT3
resolver
uniprot
Q9JJT4
resolver
uniprot
Q9JJT6
resolver
uniprot
Q9JJT7
resolver
uniprot
Q9JJT8
resolver
uniprot_entry
A2AP45_MOUSE
resolver
uniprot_entry
GFRA4_MOUSE
resolver
uniprot_entry
Q8C1V7_MOUSE
resolver
uniprot_sec
A2AP44
resolver
uniprot_sec
A2AP46
resolver
uniprot_sec
A2AP47
resolver
uniprot_sec
A2AP49
resolver
uniprot_sec
Q9JJT3
resolver
uniprot_sec
Q9JJT4
resolver
uniprot_sec
Q9JJT6
resolver
uniprot_sec
Q9JJT7
resolver
uniprot_sec
Q9JJT8
resolver
amino_acid_sequence
MAHCMESALLLLLLLGSASFTDGNRCVDAAEACTADERCQQLRSEYVARCLGRAAPGGRPGPGGCVRSRCRRALRRFFARGPPALTHALLFCGCEGSACAERRRQTFAPACAFSGPGLVPPSCLEPLERCERSRLCRPRLLAFQASCAPAPGSRDRCPEEGGPRCLRVYAGLIGTVVTPNYLDNVSARVAPWCGCAASGNRREECEAFRKLFTRNPCLDGAIQAFDSLQPSVLQDQTAGCCFPRVSWLYALTALALQALL
uniprot
proteins
function
FUNCTION: Receptor for persephin (PSPN), a growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla. {ECO:0000250|UniProtKB:Q9GZZ7}.
uniprot
proteins
mass_dalton
27990
uniprot
proteins
protein_family
GDNFR family
uniprot
proteins
pubmed
10860579
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
260
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform a1]: Cell membrane {ECO:0000305|PubMed:10860579}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9GZZ7}.; SUBCELLULAR LOCATION: [Isoform b1]: Cell membrane {ECO:0000305|PubMed:10860579}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9GZZ7}.; SUBCELLULAR LOCATION: [Isoform a3]: Secreted {ECO:0000305|PubMed:10860579}.; SUBCELLULAR LOCATION: [Isoform b3]: Secreted {ECO:0000305|PubMed:10860579}.
uniprot
proteins