Q3V0T4
uniprot
Q3V0T4
canonical
amino_acid_sequence
MVFKTIWIERYRKLINLFRALASCHGSNLDVEKPVVFKEDAASFGQTVVQFGGSRLVVGAPLEAVAVNQTGQLYDCAPATGVCQPILLHIPLEAVNMSLGLSLVADTNNSQLLACGPTAQRACAKNMYAKGSCLLLGSSLQFIQAIPATMPECPGQEMDIAFLIDGSGSIDQSDFTQMKDFVKALMGQLASTSTSFSLMQYSNILKTHFTFTEFKSSLSPQSLVDAIVQLQGLTYTASGIQKVVKELFHSKNGARKSAKKILIVITDGQKFRDPLEYRHVIPEAEKAGIIRYAIGVGDAFREPTALQELNTIGSAPSQDHVFKVGNFVALRSIQRQIQEKIFAIEGTESRSSSSFQHEMSQEGFSSALSMDGPVLGAVGSFSWSGGAFLYPSNMRSTFINMSQENEDMRDAYLGYSTALAFWKGVHSLILGAPRHQHTGKVVIFTQESRHWRPKSEVRGTQIGSYFGASLCSVDMDRDGSTDLVLIGVPHYYEHTRGGQVSVCPMPGVRSRWHCGTTLHGEQGHPWGRFGAALTVLGDVNGDSLADVAIGAPGEEENRGAVYIFHGASRQDIAPSPSQRVTGSQLFLRLQYFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVGISIRFAPSEVAKTVYQCWGRTPTVLEAGEATVCLTVRKGSPDLLGDVQSSVRYDLALDPGRLISRAIFDETKNCTLTRRKTLGLGDHCETMKLLLPDCVEDAVTPIILRLNLSLAGDSAPSRNLRPVLAVGSQDHVTASFPFEKNCKQELLCEGNLGVSFNFSGLQVLEVGSSPELTVTVTVWNEGEDSYGTLIKFYYPAELSYRRVTRAQQPHPYPLRLACEAEPTGQESLRSSSCSINHPIFREGAKATFMITFDVSYKAFLGDRLLLRASASSENNKPETSKTAFQLELPVKYTVYTVISRQEDSTKHFNFSSSHGERQKEAEHRYRVNNLSPLTLAISVNFWVPILLNGVAVWDVTLRSPAQGVSCVSQREPPQHSDLLTQIQGRSVLDCAIADCLHLRCDIPSLGTLDELDFILKGNLSFGWISQTLQKKVLLLSEAEITFNTSVYSQLPGQEAFLRAQVSTMLEEYVVYEPVFLMVFSSVGGLLLLALITVALYKLGFFKRQYKEMLDLPSADPDPAGQADSNHETPPHLTS
uniprot
proteins
function
FUNCTION: Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood. {ECO:0000250|UniProtKB:Q13349}.
uniprot
proteins
mass_dalton
127829
uniprot
proteins
protein_family
Integrin alpha chain family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1168
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q13349}; Single-pass type I membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 1108..1128; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins