Ltbp4
entrez
108075
canonical
uniprot
Q8K4G1
canonical
ensembl
ENSMUSG00000040488
resolver
ensp
ENSMUSP00000037536
resolver
ensp
ENSMUSP00000113674
resolver
genesymbol
Ltbp4
resolver
uniprot
E9QPD9
resolver
uniprot
Q3UGU1
resolver
uniprot
Q8K4G0
resolver
uniprot_entry
LTBP4_MOUSE
resolver
uniprot_entry
Q3UGU1_MOUSE
resolver
uniprot_sec
E9QPD9
resolver
uniprot_sec
Q8K4G0
resolver
amino_acid_sequence
MRRPGLGGPCPLLLLLLLPAATSASGSSPSPSPSPIEKAVVPSHQAGVAACHCCLDQTPKSSRCTRASCRVRNCPPAKCTGLEGCLTPTPSVPSPSRSPVEKSQVSLNWQPLTLQEARALLRQRRPRGPWARALLKRRPPHRAPAGQARVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAMPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEANPEALARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGSECASPLPGLRTQEVCCRGEGLAWGVHDCHPCAEHLRNSNQVSGPNGPCPPGFERVNGSCVDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCYRVLHDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPYGSEGFREICPAGPGYHYSASDLRYNTRPLNQDPPRVTFNQPRVPPATPRPPTGFLPTRRPEPRPDPGPQPEPRPRPEPRPRPESRPRPEPRPRPEPRPQPESQPRPESRPRPESQPWPEFPLPSIPAWTGPEIPESGPSSSMCQRNPQVCGPGRCVPRPSGYTCACDPGFRLGPQGTRCIDIDECRRVPTPCAPGRCENTPGSFRCVCGTGFQAGPRATECLDVDECRRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGVCENLPGSFRCVCPAGFRGSACEEDVDECAQQPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECSRSPSPCAYGRCENTEGSFKCVCPTGFQPNAAGSECEDVDECENRLACPGQECVNSPGSFQCRACPVGHHLHRGRCTDVDECSSGTPCGLHGQCTNTKGSFHCSCSTGYRAPSGQPGPCADINECLEGDFCFPHGECLNTDGSFTCTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDIDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHPGPEGTCDDIDECREYGSAICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAMCQNLPGSFQCVCDQGYEGARDGRHCVDVNECETLQGVCGSALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRAPAGTFPGSQPQAPASPSLPARPPAPPPPRRPSPPRQGPVSSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLVPSGDLSARRDVDECQLFQDQVCKSGVCVNTAPGYSCYCSNGFYYHAHRLECVDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGPDLVCSRPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGIPYEYGPDIGPPYQSLPYGPDLYPPPVLPYDPYPPPPGPFARREAPYGAPPFDMPDFEDDGGPYGESETPDPPSRGTGWPYRSRDTRGSFPEPEESSERGSYTGALSEPYEGLEAEECGILDGCPHGRCVRVPEGFTCDCFDGYRLDITRMSCVDVNECDEAEATSPLCVNARCVNTDGSFRCICRPGFAPTHQPHHCAPARPRA
uniprot
proteins
function
FUNCTION: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. {ECO:0000250|UniProtKB:Q14766}.
uniprot
proteins
mass_dalton
178642
uniprot
proteins
post_translational_modification
PTM: Contains hydroxylated asparagine residues. {ECO:0000250|UniProtKB:Q14766}.
uniprot
proteins
protein_family
LTBP family
uniprot
proteins
pubmed
12208849
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
19836010
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25713297
uniprot
proteins
sequence_length
1666
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q8N2S1}.
uniprot
proteins