Paip2
entrez
67869
canonical
uniprot
Q9D6V8
canonical
ensembl
ENSMUSG00000037058
resolver
ensp
ENSMUSP00000036021
resolver
ensp
ENSMUSP00000157456
resolver
ensp
ENSMUSP00000157519
resolver
ensp
ENSMUSP00000157742
resolver
ensp
ENSMUSP00000157936
resolver
ensp
ENSMUSP00000158160
resolver
ensp
ENSMUSP00000158248
resolver
ensp
ENSMUSP00000158496
resolver
ensp
ENSMUSP00000258604
resolver
ensp
ENSMUSP00000258627
resolver
ensp
ENSMUSP00000358598
resolver
enst
ENSMUST00000041314
resolver
enst
ENSMUST00000235210
resolver
enst
ENSMUST00000235400
resolver
enst
ENSMUST00000235476
resolver
enst
ENSMUST00000236020
resolver
enst
ENSMUST00000236414
resolver
enst
ENSMUST00000236666
resolver
enst
ENSMUST00000236868
resolver
genesymbol
Paip2
resolver
uniprot
Q3UBH5
resolver
uniprot
Q9DAW7
resolver
uniprot_entry
PAIP2_MOUSE
resolver
uniprot_sec
Q3UBH5
resolver
uniprot_sec
Q9DAW7
resolver
amino_acid_sequence
MKDPSRSSTSPSIINDDVIINGHSHEEDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY
uniprot
proteins
function
FUNCTION: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
14700
uniprot
proteins
post_translational_modification
PTM: Ubiquitinated, leading to its degradation by the proteasome. {ECO:0000250|UniProtKB:Q9BPZ3}.
uniprot
proteins
protein_family
PAIP2 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16804161
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
124
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins