JCHAIN
entrez
3512
canonical
uniprot
P01591
canonical
ensembl
ENSG00000132465
resolver
ensp
ENSP00000254801
resolver
ensp
ENSP00000426687
resolver
enst
ENST00000254801
resolver
enst
ENST00000510437
resolver
genesymbol
JCHAIN
resolver
genesymbol_syn
IGCJ
resolver
genesymbol_syn
IGJ
resolver
hgnc
HGNC:5713
resolver
uniprot_entry
IGJ_HUMAN
resolver
amino_acid_sequence
MKNHLLFWGVLAVFIKAVHVKAQEDERIVLVDNKCKCARITSRIIRSSEDPNEDIVERNIRIIVPLNNRENISDPTSPLRTRFVYHLSDLCKKCDPTEVELDNQIVTATQSNICDEDSATETCYTYDRNKCYTAVVPLVYGGETKMVETALTPDACYPD
uniprot
proteins
function
FUNCTION: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component. {ECO:0000250|UniProtKB:P01592}.
uniprot
proteins
mass_dalton
18099
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
1472500
uniprot
proteins
pubmed
15084671
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
16740002
uniprot
proteins
pubmed
18780401
uniprot
proteins
pubmed
19139490
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25946035
uniprot
proteins
pubmed
2984306
uniprot
proteins
pubmed
32029686
uniprot
proteins
pubmed
32029689
uniprot
proteins
pubmed
37095205
uniprot
proteins
pubmed
407930
uniprot
proteins
sequence_length
159
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P01592}.
uniprot
proteins