Tmem74
entrez
239408
canonical
uniprot
Q8BQU7
canonical
ensembl
ENSMUSG00000054409
resolver
ensp
ENSMUSP00000070748
resolver
ensp
ENSMUSP00000195672
resolver
enst
ENSMUST00000067469
resolver
genesymbol
Tmem74
resolver
uniprot_entry
TMM74_MOUSE
resolver
amino_acid_sequence
MELHSLSKRNSPVDPCNALEWSSGETSGDHIEEATIRDAFCYQKNLVSTPRADVVEVCRLSTSPASPTSLLQDSAIQTSFSLSGPPDSGNNQVMADRKVCNCCSQELETSFTYVDENVNLEQRSQRSPSAKGSNHPVDLGWGNPNEWSHETAMSLMSEDDDDTSSEATSSGKSVDYGFISAILFLVTGILLVIISYIVPREVTVDPNTVAAREMERLEKESAMLGAHLDRCVIAGLCLLTLGGVVLSCLLMMSMWKGELYRRNRFASSKESAKLYGSFNFRMKTSTNEDTLELSLVEEDALAVQS
uniprot
proteins
function
FUNCTION: Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33416
uniprot
proteins
protein_family
TMEM74 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
305
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 178..198; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 232..252; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins