Prok1
entrez
246691
canonical
uniprot
Q14A28
canonical
ensembl
ENSMUSG00000070368
resolver
ensp
ENSMUSP00000060617
resolver
ensp
ENSMUSP00000143197
resolver
genesymbol
Prok1
resolver
genesymbol_syn
Pk1
resolver
uniprot
Q0P609
resolver
uniprot
Q8K457
resolver
uniprot_entry
PROK1_MOUSE
resolver
uniprot_sec
Q0P609
resolver
uniprot_sec
Q8K457
resolver
amino_acid_sequence
MRGAVHIFIMLLLATASDCAVITGACERDIQCGAGTCCAISLWLRGLRLCTPLGREGEECHPGSHKIPFLRKRQHHTCPCSPSLLCSRFPDGRYRCFRDLKNANF
uniprot
proteins
function
FUNCTION: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. {ECO:0000250|UniProtKB:P58294, ECO:0000269|PubMed:12746324, ECO:0000269|PubMed:17324478, ECO:0000269|PubMed:17531315}.
uniprot
proteins
mass_dalton
11678
uniprot
proteins
protein_family
AVIT (prokineticin) family
uniprot
proteins
pubmed
12746324
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17324478
uniprot
proteins
pubmed
17531315
uniprot
proteins
sequence_length
105
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P58294}.
uniprot
proteins