SLC67A1
entrez
5002
canonical
uniprot
Q96BI1
canonical
ensembl
ENSG00000110628
resolver
ensembl
ENSG00000276130
resolver
ensp
ENSP00000307859
resolver
ensp
ENSP00000369948
resolver
ensp
ENSP00000392072
resolver
ensp
ENSP00000479357
resolver
ensp
ENSP00000480848
resolver
ensp
ENSP00000482330
resolver
ensp
ENSP00000497561
resolver
ensp
ENSP00000558550
resolver
ensp
ENSP00000558552
resolver
ensp
ENSP00000558554
resolver
ensp
ENSP00000558555
resolver
ensp
ENSP00000558556
resolver
ensp
ENSP00000558558
resolver
ensp
ENSP00000558562
resolver
ensp
ENSP00000558567
resolver
ensp
ENSP00000558568
resolver
ensp
ENSP00000618788
resolver
ensp
ENSP00000618790
resolver
enst
ENST00000347936
resolver
enst
ENST00000380574
resolver
enst
ENST00000449793
resolver
enst
ENST00000610526
resolver
enst
ENST00000615661
resolver
enst
ENST00000622105
resolver
enst
ENST00000649076
resolver
enst
ENST00000888491
resolver
enst
ENST00000888493
resolver
enst
ENST00000888495
resolver
enst
ENST00000888496
resolver
enst
ENST00000888497
resolver
enst
ENST00000888499
resolver
enst
ENST00000888503
resolver
enst
ENST00000888508
resolver
enst
ENST00000888509
resolver
enst
ENST00000948729
resolver
enst
ENST00000948731
resolver
genesymbol
SLC67A1
resolver
genesymbol_syn
BWR1A
resolver
genesymbol_syn
BWSCR1A
resolver
genesymbol_syn
HET
resolver
genesymbol_syn
IMPT1
resolver
genesymbol_syn
ITM
resolver
genesymbol_syn
ORCTL2
resolver
genesymbol_syn
SLC22A18
resolver
genesymbol_syn
SLC22A1L
resolver
genesymbol_syn
TSSC5
resolver
hgnc
HGNC:10964
resolver
uniprot
A0A024RCG2
resolver
uniprot
E9PRM7
resolver
uniprot
O14906
resolver
uniprot
O43562
resolver
uniprot
O60485
resolver
uniprot
O60680
resolver
uniprot
Q7LDS5
resolver
uniprot
Q7LGF7
resolver
uniprot_entry
A0A024RCG2_HUMAN
resolver
uniprot_entry
E9PRM7_HUMAN
resolver
uniprot_entry
S67A1_HUMAN
resolver
uniprot_sec
O14906
resolver
uniprot_sec
O43562
resolver
uniprot_sec
O60485
resolver
uniprot_sec
O60680
resolver
uniprot_sec
Q7LDS5
resolver
uniprot_sec
Q7LGF7
resolver
amino_acid_sequence
MQGARAPRDQGRSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
uniprot
proteins
disease_involvement
DISEASE: Lung cancer (LNCR) [MIM:211980]: A common malignancy affecting tissues of the lung. The most common form of lung cancer is non-small cell lung cancer (NSCLC) that can be divided into 3 major histologic subtypes: squamous cell carcinoma, adenocarcinoma, and large cell lung cancer. NSCLC is often diagnosed at an advanced stage and has a poor prognosis. {ECO:0000269|PubMed:9751628}. Note=The gene represented in this entry may be involved in disease pathogenesis.; DISEASE: Rhabdomyosarcoma, embryonal, 1 (RMSE1) [MIM:268210]: A form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchymal cells and exhibiting differentiation along rhabdomyoblastic lines. Rhabdomyosarcoma is one of the most frequently occurring soft tissue sarcomas and the most common in children. It occurs in four forms: alveolar, pleomorphic, embryonal and botryoidal rhabdomyosarcomas. {ECO:0000269|PubMed:9520460}. Note=The disease may be caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney (PubMed:9744804). Plays a role in the regulation of lipid metabolism (By similarity). {ECO:0000250|UniProtKB:Q78KK3, ECO:0000269|PubMed:9744804}.
uniprot
proteins
mass_dalton
44846
uniprot
proteins
protein_family
Major facilitator (TC 2.A.1) superfamily
uniprot
proteins
protein_family
Organic cation transporter (TC 2.A.1.19) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16314844
uniprot
proteins
pubmed
26536134
uniprot
proteins
pubmed
9499412
uniprot
proteins
pubmed
9520460
uniprot
proteins
pubmed
9570947
uniprot
proteins
pubmed
9744804
uniprot
proteins
pubmed
9751628
uniprot
proteins
pubmed
9802569
uniprot
proteins
sequence_length
424
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:9744804}; Multi-pass membrane protein {ECO:0000305}. Note=Localized at the apical membrane surface of renal proximal tubules. {ECO:0000269|PubMed:9744804}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..46; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 59..79; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 90..110; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 156..176; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 184..204; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 243..263; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 276..296; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 312..332; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 334..354; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 391..411; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins