TSPO2
entrez
222642
canonical
uniprot
Q5TGU0
canonical
ensembl
ENSG00000112212
resolver
ensp
ENSP00000362255
resolver
ensp
ENSP00000419985
resolver
ensp
ENSP00000772927
resolver
ensp
ENSP00000772930
resolver
genesymbol
TSPO2
resolver
genesymbol_syn
BZRPL1
resolver
hgnc
HGNC:21256
resolver
uniprot
B2RPR2
resolver
uniprot
B7ZMN8
resolver
uniprot
Q3SX82
resolver
uniprot_entry
TSPO2_HUMAN
resolver
uniprot_sec
B2RPR2
resolver
uniprot_sec
B7ZMN8
resolver
uniprot_sec
Q3SX82
resolver
amino_acid_sequence
MRLQGAIFVLLPHLGPILVWLFTRDHMSGWCEGPRMLSWCPFYKVLLLVQTAIYSVVGYASYLVWKDLGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPINKLAALLLLPYLAWLTVTSALTYHLWRDSLCPVHQPQPTEKSD
uniprot
proteins
function
FUNCTION: Cholesterol-binding protein involved in the redistribution of cholesterol from lipid droplets to the endoplasmic reticulum (PubMed:19729679). Required to meet cholesterol demands during erythropoietic differentiation (PubMed:19729679). May play a role in transport processes at the plasma membrane of erythrocytes, including regulating VDAC-mediated ATP export, and import of the heme precursors protoporphyrin IX and 5-aminolevulinic acid (PubMed:27641616, PubMed:30061676, PubMed:31989647). {ECO:0000269|PubMed:19729679, ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:30061676, ECO:0000269|PubMed:31989647}.
uniprot
proteins
mass_dalton
19129
uniprot
proteins
protein_family
TspO/BZRP family
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19729679
uniprot
proteins
pubmed
27641616
uniprot
proteins
pubmed
30061676
uniprot
proteins
pubmed
31989647
uniprot
proteins
sequence_length
170
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19729679}; Multi-pass membrane protein {ECO:0000269|PubMed:19729679}. Cell membrane {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:31989647}; Multi-pass membrane protein. Note=Localizes to the plasma membrane and intracellular membranes in developing and mature erythrocytes. {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:31989647}.
uniprot
proteins
transmembrane_region
TRANSMEM 3..23; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 45..65; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 78..98; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 104..124; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 130..150; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins