GPR42
entrez
2866
canonical
uniprot
O15529
canonical
ensembl
ENSG00000126251
resolver
ensp
ENSP00000410925
resolver
ensp
ENSP00000473212
resolver
enst
ENST00000454971
resolver
enst
ENST00000597214
resolver
genesymbol
GPR42
resolver
genesymbol_syn
GPR42P
resolver
hgnc
HGNC:4500
resolver
uniprot_entry
GPR42_HUMAN
resolver
amino_acid_sequence
MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLRCRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLVAATLLNFLVCFGPYNVSHVVGYICGESPVWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAEN
uniprot
proteins
function
FUNCTION: G protein-coupled receptor that is activated by short chain fatty acids (SCFAs), such as propionate. Hence may play a role in the regulation of whole-body energy homeostasis and/or in intestinal immunity. {ECO:0000269|PubMed:19630535}.
uniprot
proteins
mass_dalton
38665
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
12496283
uniprot
proteins
pubmed
15057824
uniprot
proteins
pubmed
19630535
uniprot
proteins
pubmed
9344866
uniprot
proteins
sequence_length
346
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 20..40; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 48..68; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 91..111; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 133..153; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 179..199; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 223..243; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 259..279; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins