Slc17a4
entrez
319848
canonical
uniprot
Q5NCM1
canonical
ensembl
ENSMUSG00000021336
resolver
ensp
ENSMUSP00000021769
resolver
ensp
ENSMUSP00000106037
resolver
ensp
ENSMUSP00000196095
resolver
enst
ENSMUST00000021769
resolver
enst
ENSMUST00000110407
resolver
genesymbol
Slc17a4
resolver
uniprot
A0A2C9F2D4
resolver
uniprot
B9EJP0
resolver
uniprot
Q8BWR0
resolver
uniprot_entry
A0A2C9F2D4_MOUSE
resolver
uniprot_entry
Q8BWR0_MOUSE
resolver
uniprot_entry
S17A4_MOUSE
resolver
uniprot_sec
B9EJP0
resolver
amino_acid_sequence
MSTGADLKAREGDIPSDNMTQEQSFKKGFCSLRHGLAFILHLCNFSIYTQQMNLSFAITAMVNTTVASSQLNASTERPPTNSQDVWNETLQESKAPVYDWTPEIQGILLSSLSYGSFIAPIPTGYVAGVFGAKYVVGLGLLISSVLTLFIPLAADAGVALLIVLRVIQGMAQVMVLTGQYSLWAKWAPPQERSQLITIAASGSMLGTFLVLIAGGLICQALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGERRYITCSLAQEDCSLGWSLPIKAMVKSLPLWAIVVSYFCEYWLLSTVMAYTPTYISSVLQANLRDSGILSALPFMFGCVCIILGGLLADFLLSRKILRLVTIRKLFTAVGVLASSGILLPLPWVRSSRSTTMAFLVLSSVFASLCDSGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEFGWRNVFFLAAAIDVVGLLFYLIFSRAEVQDWAKEPTFTHL
uniprot
proteins
function
FUNCTION: Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions (PubMed:22460716). Mediates chloride-dependent transport of urate (PubMed:22460716). Mediates sodium-independent high affinity transport of thyroid hormones including L-thyroxine (T4) and 3,3',5-triiodo-L-thyronine (T3) (By similarity). Can actively transport inorganic phosphate into cells via Na(+) cotransport (By similarity). {ECO:0000250|UniProtKB:Q9Y2C5, ECO:0000269|PubMed:22460716}.
uniprot
proteins
mass_dalton
53668
uniprot
proteins
protein_family
Major facilitator superfamily
uniprot
proteins
protein_family
Sodium/anion cotransporter family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
22460716
uniprot
proteins
sequence_length
492
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000269|PubMed:22460716}; Multi-pass membrane protein {ECO:0000255}. Note=Apical in the intestinal brush border. {ECO:0000269|PubMed:22460716}.
uniprot
proteins
transmembrane_region
TRANSMEM 112..132; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 134..154; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 156..176; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 198..218; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 225..245; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 287..307; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 327..347; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 363..383; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 393..413; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 426..446; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 456..476; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins