STOML1
entrez
9399
canonical
uniprot
Q9UBI4
canonical
ensembl
ENSG00000067221
resolver
ensp
ENSP00000319323
resolver
ensp
ENSP00000319384
resolver
ensp
ENSP00000352788
resolver
ensp
ENSP00000442478
resolver
ensp
ENSP00000456343
resolver
ensp
ENSP00000456853
resolver
ensp
ENSP00000656732
resolver
enst
ENST00000561656
resolver
genesymbol
STOML1
resolver
genesymbol_syn
SLP1
resolver
genesymbol_syn
UNC24
resolver
hgnc
HGNC:14560
resolver
uniprot
B3KQN0
resolver
uniprot
B4DUU5
resolver
uniprot
B4DXM9
resolver
uniprot
E7ESC0
resolver
uniprot
H3BRP3
resolver
uniprot
H3BST3
resolver
uniprot
O95675
resolver
uniprot
Q4PNR4
resolver
uniprot
Q53HB6
resolver
uniprot
Q6FGL8
resolver
uniprot
Q8WYI7
resolver
uniprot
Q9UMB9
resolver
uniprot
Q9UMC0
resolver
uniprot
Q9Y6H9
resolver
uniprot_entry
H3BST3_HUMAN
resolver
uniprot_entry
Q53HB6_HUMAN
resolver
uniprot_entry
STML1_HUMAN
resolver
uniprot_sec
B3KQN0
resolver
uniprot_sec
B4DUU5
resolver
uniprot_sec
B4DXM9
resolver
uniprot_sec
E7ESC0
resolver
uniprot_sec
H3BRP3
resolver
uniprot_sec
O95675
resolver
uniprot_sec
Q4PNR4
resolver
uniprot_sec
Q6FGL8
resolver
uniprot_sec
Q8WYI7
resolver
uniprot_sec
Q9UMB9
resolver
uniprot_sec
Q9UMC0
resolver
uniprot_sec
Q9Y6H9
resolver
amino_acid_sequence
MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPERGGVGTGADVPQSWPSCLCHGLISFLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQQLALHFLGGSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTALQPFLSEALVSQVGACYQFNVVLPSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLRALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRALK
uniprot
proteins
function
FUNCTION: May play a role in cholesterol transfer to late endosomes (PubMed:19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed:23082202). {ECO:0000250|UniProtKB:Q8CI66, ECO:0000269|PubMed:19696025, ECO:0000305|PubMed:23082202}.
uniprot
proteins
mass_dalton
42968
uniprot
proteins
mutagenesis
MUTAGEN 7; /note="Y->A: Plasma membrane localization."; /evidence="ECO:0000269|PubMed:19696025"; MUTAGEN 10; /note="L->S: Plasma membrane localization."; /evidence="ECO:0000269|PubMed:19696025
uniprot
proteins
protein_family
Band 7/mec-2 family
uniprot
proteins
pubmed
10997330
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16303743
uniprot
proteins
pubmed
16572171
uniprot
proteins
pubmed
19696025
uniprot
proteins
pubmed
23082202
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
9931417
uniprot
proteins
sequence_length
398
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. Late endosome membrane {ECO:0000269|PubMed:19696025}. Membrane raft {ECO:0000269|PubMed:19696025}. Cell membrane {ECO:0000250|UniProtKB:Q8CI66}; Single-pass type III membrane protein. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q8CI66}.
uniprot
proteins
transmembrane_region
TRANSMEM 58..78; /note="Helical; Signal-anchor for type III membrane protein"; /evidence="ECO:0000255
uniprot
proteins