Il1rl2
entrez
107527
canonical
uniprot
Q9ERS7
canonical
ensembl
ENSMUSG00000070942
resolver
ensp
ENSMUSP00000092630
resolver
ensp
ENSMUSP00000142248
resolver
ensp
ENSMUSP00000193836
resolver
enst
ENSMUST00000095020
resolver
enst
ENSMUST00000194296
resolver
genesymbol
Il1rl2
resolver
uniprot
Q149G7
resolver
uniprot_entry
ILRL2_MOUSE
resolver
uniprot_entry
Q149G7_MOUSE
resolver
amino_acid_sequence
MGVTSLLFCGVFFLLLLFVAADTCEDIFMHNVIISEGQPFPFNCTYPPETNGAVNLTWYKTPSKSPVSNNRHLRVHQDQTWILFLPLTLEDSGIYQCVIRNAHNCYQIAVNLTVLKNHWCDSSMEGSPVNSPDVYQQILPIGKSGSLNCHLYFPESCALDSIKWYKGCEEIKAGKKYSPSGAKLLVNNVAVEDGGSYACSARLTHLGRHFTIRNYIAVNTKEVEYGRRIPNITYPKNNSIEVPLGSTLIVNCNITDTKENTNLRCWRVNNTLVDDYYKDSKRIQEGIETNVSLRDQIRYTVNITFLKVKMEDYGRPFTCHAGVSAAYIILIYPVPDFRAYLLGGLMAFLLLVVSVLFIYNSFKIDIMLWYRSAFHTAQAPDDEKLYDAYVLYPKYPRGSQGHDVDTLVLKILPEVLEKQCGYKLFIFGRDEFPGQAVASVIDENIKLCRRLMVFVAPESSSFGFLKNLSEEQIAVYNALIQHGMKVILIELEKVKDYSTMPESIQYIRQKHGAIQWDGDFTEQSQCAKTKFWKKVRYHMPPRRYPASSPVQLLGHIPCNCKAGKCNAATGLITP
uniprot
proteins
ec_number
3.2.2.6
uniprot
proteins
function
FUNCTION: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. {ECO:0000269|PubMed:21860022, ECO:0000269|PubMed:23064362}.
uniprot
proteins
mass_dalton
65108
uniprot
proteins
protein_family
Interleukin-1 receptor family
uniprot
proteins
pubmed
10882729
uniprot
proteins
pubmed
21860022
uniprot
proteins
pubmed
21965679
uniprot
proteins
pubmed
23064362
uniprot
proteins
sequence_length
574
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 339..359; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins