Chrdl2
entrez
69121
canonical
uniprot
Q8VEA6
canonical
ensembl
ENSMUSG00000030732
resolver
ensp
ENSMUSP00000032977
resolver
ensp
ENSMUSP00000102699
resolver
enst
ENSMUST00000032977
resolver
enst
ENSMUST00000107084
resolver
genesymbol
Chrdl2
resolver
genesymbol_syn
Chl2
resolver
uniprot
A0A0B4J1E8
resolver
uniprot
D3YV59
resolver
uniprot
Q925I3
resolver
uniprot_entry
A0A0B4J1E8_MOUSE
resolver
uniprot_entry
CRDL2_MOUSE
resolver
uniprot_entry
D3YV59_MOUSE
resolver
uniprot_sec
Q925I3
resolver
amino_acid_sequence
MVPGVRIIPSLLGLVMFWLPLDSQARSRSGKVCLFGEKIYTPGQSWHPYLEPQGTIYCVRCTCSENGHVNCYRLRCPPLHCSQPVMEPQQCCPRCVDPHVPSGLRVPLKSCQLNETTYQHGEIFSAQELFPARLSNQCVLCSCIEGHTYCGLMTCPEPSCPTTLPLPDSCCQTCKDRTTESSTEENLTQLQHGERHSQDPCSERRGPSTPAPTSLSSPLGFIPRHFQSVGMGSTTIKIILKEKHKKACTHNGKTYSHGEVWHPTVLSFGPMPCILCTCIDGYQDCHRVTCPTQYPCSQPKKVAGKCCKICPEDEAEDDHSEVISTRCPKVPGQFHVYTLASPSPDSLHRFVLEHEASDQVEMYIWKLVKGIYHLVQIKRVRKQDFQKEAQNFRLLTGTHEGYWTVFLAQTPELKVTASPDKVTKTL
uniprot
proteins
function
FUNCTION: Implicated in tumor angiogenesis (By similarity). May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. May play a role during myoblast and osteoblast differentiation, and maturation. {ECO:0000250, ECO:0000269|PubMed:14660436, ECO:0000269|PubMed:15094188}.
uniprot
proteins
mass_dalton
47765
uniprot
proteins
pubmed
14660436
uniprot
proteins
pubmed
15094188
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
426
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
uniprot
proteins