RPL8
entrez
6132
canonical
uniprot
P62917
canonical
ensembl
ENSG00000161016
resolver
ensp
ENSP00000262584
resolver
ensp
ENSP00000378378
resolver
ensp
ENSP00000433464
resolver
enst
ENST00000262584
resolver
enst
ENST00000394920
resolver
enst
ENST00000528957
resolver
genesymbol
RPL8
resolver
hgnc
HGNC:10368
resolver
uniprot
A8K094
resolver
uniprot
D3DWN2
resolver
uniprot
P25120
resolver
uniprot
Q567Q7
resolver
uniprot
Q969V7
resolver
uniprot
Q9BWQ9
resolver
uniprot_entry
RL8_HUMAN
resolver
uniprot_sec
A8K094
resolver
uniprot_sec
D3DWN2
resolver
uniprot_sec
P25120
resolver
uniprot_sec
Q567Q7
resolver
uniprot_sec
Q969V7
resolver
uniprot_sec
Q9BWQ9
resolver
amino_acid_sequence
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN
uniprot
proteins
function
FUNCTION: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. {ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:32669547, ECO:0000305|PubMed:12962325}.
uniprot
proteins
mass_dalton
28025
uniprot
proteins
mutagenesis
MUTAGEN 209; /note="H->A,G: No incorporation into translating E.coli polysomes; ribosomes assembled normally. Significantly reduced translational activity."; /evidence="ECO:0000269|PubMed:9531480
uniprot
proteins
post_translational_modification
PTM: Hydroxylated on His-216 by RIOX1. The modification is impaired by hypoxia. {ECO:0000269|PubMed:23103944}.
uniprot
proteins
protein_family
Universal ribosomal protein uL2 family
uniprot
proteins
pubmed
11875025
uniprot
proteins
pubmed
12962325
uniprot
proteins
pubmed
14654843
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15592455
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23103944
uniprot
proteins
pubmed
23636399
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
24524803
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
32669547
uniprot
proteins
pubmed
7506540
uniprot
proteins
pubmed
9531480
uniprot
proteins
pubmed
9582194
uniprot
proteins
sequence_length
257
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23636399}.
uniprot
proteins