DDX3Y
entrez
8653
canonical
uniprot
O15523
canonical
ensembl
ENSG00000067048
resolver
ensp
ENSP00000336725
resolver
ensp
ENSP00000353284
resolver
ensp
ENSP00000564575
resolver
ensp
ENSP00000665746
resolver
genesymbol
DDX3Y
resolver
genesymbol_syn
DBY
resolver
hgnc
HGNC:2699
resolver
uniprot
B4DK29
resolver
uniprot
B4DXX7
resolver
uniprot
Q8IYV7
resolver
uniprot_entry
DDX3Y_HUMAN
resolver
uniprot_sec
B4DK29
resolver
uniprot_sec
B4DXX7
resolver
uniprot_sec
Q8IYV7
resolver
amino_acid_sequence
MSHVVVKNDPELDQQLANLDLNSEKQSGGASTASKGRYIPPHLRNREASKGFHDKDSSGWSCSKDKDAYSSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGRFERSGHSRWCDKSVEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
uniprot
proteins
disease_involvement
DISEASE: Note=Located in the 'azoospermia factor a' (AZFa) region on chromosome Y which is deleted in Sertoli cell-only syndrome. This is an infertility disorder in which no germ cells are visible in seminiferous tubules leading to azoospermia.
uniprot
proteins
ec_number
3.6.4.13
uniprot
proteins
function
FUNCTION: Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). {ECO:0000250|UniProtKB:Q62095}.
uniprot
proteins
mass_dalton
73154
uniprot
proteins
protein_family
DDX3/DED1 subfamily
uniprot
proteins
protein_family
DEAD box helicase family
uniprot
proteins
pubmed
12815422
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15294876
uniprot
proteins
pubmed
15383328
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
9381176
uniprot
proteins
sequence_length
660
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15294876, ECO:0000269|PubMed:15383328}. Nucleus {ECO:0000269|PubMed:15383328}. Note=Shuttles between the nucleus and the cytoplasm in an XPO1-dependent manner.
uniprot
proteins