Hycc1
entrez
84652
canonical
uniprot
Q6P9N1
canonical
ensembl
ENSMUSG00000028995
resolver
ensp
ENSMUSP00000030849
resolver
ensp
ENSMUSP00000099050
resolver
ensp
ENSMUSP00000216980
resolver
ensp
ENSMUSP00000216990
resolver
ensp
ENSMUSP00000216991
resolver
ensp
ENSMUSP00000216998
resolver
ensp
ENSMUSP00000217000
resolver
genesymbol
Hycc1
resolver
genesymbol_syn
Drctnnb1a
resolver
genesymbol_syn
Fam126a
resolver
uniprot
D3Z481
resolver
uniprot
Q3TTP7
resolver
uniprot
Q99NC4
resolver
uniprot_entry
HYCCI_MOUSE
resolver
uniprot_sec
D3Z481
resolver
uniprot_sec
Q3TTP7
resolver
uniprot_sec
Q99NC4
resolver
amino_acid_sequence
MFTSEIGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVTSLYKVIQEPQSELLEPVCHQLFEFYRSGEEQLLRFTLQFLPELMWCYLAVSASRDVHSSGCIEALLLGVYNLEIVDKHGHSKVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEVLTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYRGVSSRIPISSGFMVQMLTGVYFAIYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGAMKSSKEGTRCIQVEITPTSSRISRNAVTSMSIRGHRWKRHGDTELTGQEELMDITEVDEGFYSRAASSTSQSGLSNSSHNCSNKTSVGKNQRRSGGSKAGAKERETAGESCRDHFARKQTQRAQSENLELLSLKRLTLTSSQSLPKPSSQGLAKTAATVFSKSFEQVSGAPVPRSPSPAIGCVAGADANRFSACSLQEEKLIYVSERTELAVKCQAGQQGPPSISVTLSAE
uniprot
proteins
function
FUNCTION: Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. HYCC1 plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P. Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system. May also have a role in the beta-catenin/Lef signaling pathway. {ECO:0000250|UniProtKB:Q9BYI3}.
uniprot
proteins
mass_dalton
57321
uniprot
proteins
protein_family
Hyccin family
uniprot
proteins
pubmed
10910037
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22461884
uniprot
proteins
pubmed
26571211
uniprot
proteins
sequence_length
521
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9BYI3}. Cell membrane {ECO:0000250|UniProtKB:Q9BYI3}. Note=Localizes to the cytosol and is recruited to the plasma membrane following interaction with other components of the phosphatidylinositol 4-kinase (PI4K) complex. {ECO:0000250|UniProtKB:Q9BYI3}.
uniprot
proteins