Agtr1b
entrez
11608
canonical
uniprot
P29755
canonical
ensembl
ENSMUSG00000054988
resolver
ensp
ENSMUSP00000068298
resolver
enst
ENSMUST00000068316
resolver
genesymbol
Agtr1b
resolver
uniprot
Q32MF7
resolver
uniprot
Q8BU69
resolver
uniprot_entry
AGTRB_MOUSE
resolver
uniprot_entry
Q32MF7_MOUSE
resolver
uniprot_entry
Q8BU69_MOUSE
resolver
amino_acid_sequence
MILNSSIEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYQWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFVIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFSFLDVLIQLGVIHDCEIADVVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKARSHAGLSTKMSTLSYRPSDNMSSSARKSAYCFEVE
uniprot
proteins
function
FUNCTION: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. {ECO:0000250|UniProtKB:P30556}.
uniprot
proteins
mass_dalton
40950
uniprot
proteins
post_translational_modification
PTM: C-terminal Ser or Thr residues may be phosphorylated. {ECO:0000250|UniProtKB:P30556}.
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
1497638
uniprot
proteins
pubmed
1599461
uniprot
proteins
sequence_length
359
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P30556}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P30556}.
uniprot
proteins
transmembrane_region
TRANSMEM 26..55; /note="Helical; Name=1"; /evidence="ECO:0000250|UniProtKB:P30556"; TRANSMEM 62..89; /note="Helical; Name=2"; /evidence="ECO:0000250|UniProtKB:P30556"; TRANSMEM 99..125; /note="Helical; Name=3"; /evidence="ECO:0000250|UniProtKB:P30556"; TRANSMEM 142..165; /note="Helical; Name=4"; /evidence="ECO:0000250|UniProtKB:P30556"; TRANSMEM 191..216; /note="Helical; Name=5"; /evidence="ECO:0000250|UniProtKB:P30556"; TRANSMEM 240..268; /note="Helical; Name=6"; /evidence="ECO:0000250|UniProtKB:P30556"; TRANSMEM 279..304; /note="Helical; Name=7"; /evidence="ECO:0000250|UniProtKB:P30556
uniprot
proteins