Psme3ip1
entrez
102122
canonical
uniprot
Q91WE2
canonical
ensembl
ENSMUSG00000031774
resolver
ensp
ENSMUSP00000034226
resolver
ensp
ENSMUSP00000148506
resolver
enst
ENSMUST00000034226
resolver
genesymbol
Psme3ip1
resolver
genesymbol_syn
Fam192a
resolver
genesymbol_syn
Nip30
resolver
uniprot
Q3U9X3
resolver
uniprot
Q8R0C9
resolver
uniprot_entry
PIP30_MOUSE
resolver
uniprot_sec
Q3U9X3
resolver
uniprot_sec
Q8R0C9
resolver
amino_acid_sequence
MDGEDDSNLVIKKRFVSEAELDERRKRRQEEWEKVRKPEDPKECPEEAYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELEELKEYRSNLNKVGISAENKEVEKKLAVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPDPDDKAQEAPSCMSLGSSSLSGPPSIHCPSAAVCIGILPGLGAYSGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP
uniprot
proteins
function
FUNCTION: Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus. {ECO:0000250|UniProtKB:Q9GZU8}.
uniprot
proteins
mass_dalton
28702
uniprot
proteins
post_translational_modification
PTM: Phosphorylation by CK2 stabilizes the interaction with PSME3. {ECO:0000250|UniProtKB:Q9GZU8}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
26497270
uniprot
proteins
sequence_length
254
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:26497270}.
uniprot
proteins