Sdcbp2
entrez
311532
canonical
uniprot
Q4KLN0
canonical
ensembl
ENSRNOG00000009528
resolver
ensp
ENSRNOP00000012690
resolver
enst
ENSRNOT00000012690
resolver
genesymbol
Sdcbp2
resolver
uniprot_entry
SDCB2_RAT
resolver
amino_acid_sequence
MSVLYPSLEDLKVGQVIQAQARASPMMPTVMPTLPASMASAPPLSELYPNLAELESYMGLSLSSQEVQKNLSQIPDGDNMVITSPGPGQVTAPVSGNDLGVLRAEIKPGVREIHLCKDERGKTGLRLQAVDKGLFVQLVQANTPASLVGLRFGDQILQIDGCDCAGWSTHKAQKALKKASAEKIVMVVRDRPFQRTVTMHKDSSGQVGFFIKKGKIVSVVKGSSAARNGLLTNHYVCEVNGQNVIGLKDKKIIEILTTAGNVITLTIIPTVIYEHMIKKLSPLLLHHTMDHSIPDT
uniprot
proteins
function
FUNCTION: Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival. {ECO:0000250|UniProtKB:Q9H190}.
uniprot
proteins
mass_dalton
31965
uniprot
proteins
pubmed
11152476
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
296
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H190}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9H190}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q9H190}. Cell membrane {ECO:0000250|UniProtKB:Q9H190}. Nucleus speckle {ECO:0000250|UniProtKB:Q9H190}. Note=Associates with intracellular membranes and enriched in the apical region of the cell and in intracellular compartments. Colocalizes with TM4SF1 in the apical region of the cell. Predominantly targeted to nuclear PIP2 pools. Shuttles between several subcellular compartments. PIP2 plays an important role in the distribution of SDCBP2. {ECO:0000250|UniProtKB:Q9H190}.
uniprot
proteins