Scd4
entrez
329065
canonical
uniprot
Q6T707
canonical
ensembl
ENSMUSG00000050195
resolver
ensp
ENSMUSP00000059860
resolver
enst
ENSMUST00000058856
resolver
genesymbol
Scd4
resolver
uniprot
B9EIY5
resolver
uniprot_entry
SCD4_MOUSE
resolver
uniprot_sec
B9EIY5
resolver
amino_acid_sequence
MTAHLPQEISSRCSTTNIMEPHSRRQQDGEEKMPLQAEDIRPEIKDDLYDPSYQDEEGPPPKLEYVWRNIIFMALLHVGALYGITLVPSCKVYTWLLGVFYNVVAGLGITAGAHRLWSHRTYKARLPLRIFLIMANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGKNLDMSDLKAEKLVMFQRRYYKLAVTLMFIILPTLVPWYLWGETFQHSLCVSNFLRYAVLLNFTWLVNSAAHLYGYRPYDRGIGARENPFVSMASLGEGFHNYHHTFPYDYSVSEYRWHINFTTFFIDCMAALGLAYDRKKVSKAVVLARIKRTGDGSHKSS
uniprot
proteins
ec_number
1.14.19.1
uniprot
proteins
function
FUNCTION: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:12815040, PubMed:16443825). Required for the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). {ECO:0000250|UniProtKB:O00767, ECO:0000269|PubMed:12815040, ECO:0000269|PubMed:16443825}.
uniprot
proteins
mass_dalton
41042
uniprot
proteins
protein_family
Fatty acid desaturase type 1 family
uniprot
proteins
pubmed
12815040
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16118274
uniprot
proteins
pubmed
16443825
uniprot
proteins
pubmed
19468303
uniprot
proteins
sequence_length
353
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O00767}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O00767}. Microsome membrane {ECO:0000269|PubMed:12815040, ECO:0000269|PubMed:16443825}.
uniprot
proteins
transmembrane_region
TRANSMEM 67..87; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O00767"; TRANSMEM 92..112; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O00767"; TRANSMEM 212..231; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O00767"; TRANSMEM 236..257; /note="Helical"; /evidence="ECO:0000250|UniProtKB:O00767
uniprot
proteins