Mmrn2
entrez
105450
canonical
uniprot
A6H6E2
canonical
ensembl
ENSMUSG00000041445
resolver
ensp
ENSMUSP00000107539
resolver
genesymbol
Mmrn2
resolver
uniprot
Q8BJX4
resolver
uniprot
Q8K1Z7
resolver
uniprot_entry
MMRN2_MOUSE
resolver
uniprot_sec
Q8BJX4
resolver
uniprot_sec
Q8K1Z7
resolver
amino_acid_sequence
MIPTLLLGFGVYLSWGLLGSWAQDPGTKFSHLNRPGMPEGWRLGAEDTSRDPIRRNWCPYQKSRLVTFVAACKTEKFLVHSQQPCPQGAPDCQGVRVMYRVAQKPVYQVQQKVLISVDWRCCPGFQGPDCQDHNPTANPEPTEPSGKLQETWDSMDGFELGHPVPEFNEIKVPQEQQENLLQNLQNDAQSVEDGFPGSWEAPPSNLTDEMTEANLTEFEFPGRTSEHLLQPHIDAFLKAHFSPIWKNFNDSLHSLSQAIRNLSLDVEANHQAIKMIQEGTVARADFQELGAKFEAKVQQNSQRLGQLWQDVEDQLHAQRRSVHHALSDVQAEVSTKLKQLVKAQELPGANGSLVMASAAAAARPEPESLQARLGQLQRNLSALHMVTSQREEELQSTLKNMDSVLKQHAEEIKELYSESDETFDQISKVERQVEELLVNHTGLRELRVILMEKSLIMEENKEEIERQLLELNLTLQHLHAGHADLIKYVKDCNCQRVNSDVDVAPEGHRDVMHTLEETQVSLDEQHQLDGSSLQALQSTVDAMSSAMDAYRGEGERARAERARIRSQLRALDHAVEALKTAANGTRKEIRLLHGSFTALLEDALRHQAVLAALFGEEMIDEMSEEAPRPLPLDYEQIRLALQDAASGLQEQAIGWEDLATRVEALEKAAGGFVEQHPQLAEGLEPSHDSGREEEAMTLAELEQEIRRLSSDVKQIGQCCEASWAASLNSSLEDLHSMLLDTQHGLRQHRQLFHNLFQNFQGLVASNISLDLGKLQAMLSKKDKKQPRGPGESRKRDKKQVVMSTDAHAKGLELWETGSPVAFYAGSSEGATALQMVKFNTTSINVGSSYFPEHGYFRAPKRGVYLFAVSITFGPGPGMGQLVFEGHHRVPVYSTEQRGGSTATTFAMVELQKGERAWFELIQGSATKGSQPGTAFGGFLMFKT
uniprot
proteins
function
FUNCTION: Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor. {ECO:0000250|UniProtKB:Q9H8L6}.
uniprot
proteins
mass_dalton
105206
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:Q9H8L6}.; PTM: Processed by matrix metalloproteinases (MMPs) including MMP9 and, to a lesser degree, by MMP2 upon angiogenic stimulation. {ECO:0000250|UniProtKB:Q9H8L6}.; PTM: O-fucosylated within the EMI domain (at Ser-63 and Thr-67) by POFUT3 and POFUT4. {ECO:0000250|UniProtKB:Q9H8L6}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
31422156
uniprot
proteins
sequence_length
943
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9H8L6}.
uniprot
proteins