Ciao2b
entrez
68523
canonical
uniprot
Q9D187
canonical
ensembl
ENSMUSG00000031879
resolver
ensp
ENSMUSP00000132725
resolver
enst
ENSMUST00000164884
resolver
genesymbol
Ciao2b
resolver
genesymbol_syn
Fam96b
resolver
genesymbol_syn
Mip18
resolver
uniprot_entry
CIA2B_MOUSE
resolver
amino_acid_sequence
MVGGGGSGGGLLENANPLIYERSGERPVTAGEEDEEVPDSIDAREIFDLIRSINDPEHPLTLEELNVVEQVRIQVSDPESTVAVAFTPTIPHCSMATLIGLSIKVKLLRSLPQRFKMDVHITPGTHASEHAVNKQLADKERVAAALENTHLLEVVNQCLSARS
uniprot
proteins
function
FUNCTION: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Together with MMS19, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization of KIF4A to mitotic machinery components to promote the progression of mitosis. {ECO:0000250|UniProtKB:Q9Y3D0}.
uniprot
proteins
mass_dalton
17667
uniprot
proteins
protein_family
MIP18 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
163
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y3D0}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9Y3D0}.
uniprot
proteins