DERA
entrez
51071
canonical
uniprot
Q9Y315
canonical
ensembl
ENSG00000023697
resolver
ensp
ENSP00000416583
resolver
ensp
ENSP00000431757
resolver
ensp
ENSP00000436999
resolver
enst
ENST00000428559
resolver
enst
ENST00000526530
resolver
enst
ENST00000532964
resolver
genesymbol
DERA
resolver
hgnc
HGNC:24269
resolver
uniprot
E9PPM8
resolver
uniprot
G3V158
resolver
uniprot
Q53HN9
resolver
uniprot
Q6PHW2
resolver
uniprot_entry
DEOC_HUMAN
resolver
uniprot_entry
E9PPM8_HUMAN
resolver
uniprot_entry
G3V158_HUMAN
resolver
uniprot_sec
Q53HN9
resolver
uniprot_sec
Q6PHW2
resolver
amino_acid_sequence
MSAHNRGTELDLSWISKIQVNHPAVLRRAEQIQARRTVKKEWQAAWLLKAVTFIDLTTLSGDDTSSNIQRLCYKAKYPIREDLLKALNMHDKGITTAAVCVYPARVCDAVKALKAAGCNIPVASVAAGFPAGQTHLKTRLEEIRLAVEDGATEIDVVINRSLVLTGQWEALYDEIRQFRKACGEAHLKTILATGELGTLTNVYKASMIAMMAGSDFIKTSTGKETVNATFPVAIVMLRAIRDFFWKTGNKIGFKPAGGIRSAKDSLAWLSLVKEELGDEWLKPELFRIGASTLLSDIERQIYHHVTGRYAAYHDLPMS
uniprot
proteins
ec_number
4.1.2.4
uniprot
proteins
function
FUNCTION: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation. {ECO:0000269|PubMed:25229427}.
uniprot
proteins
mass_dalton
35231
uniprot
proteins
mutagenesis
MUTAGEN 218; /note="K->A: Abolishes deoxyribose-phosphate aldolase activity."; /evidence="ECO:0000269|PubMed:25229427"; MUTAGEN 254; /note="K->A: Abolishes deoxyribose-phosphate aldolase activity."; /evidence="ECO:0000269|PubMed:25229427
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.
uniprot
proteins
protein_family
DeoC type 2 subfamily
uniprot
proteins
protein_family
DeoC/FbaB aldolase family
uniprot
proteins
pubmed
10810093
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25229427
uniprot
proteins
sequence_length
318
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:25229427}. Cytoplasmic granule {ECO:0000269|PubMed:25229427}. Nucleus {ECO:0000269|PubMed:25229427}. Note=Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation. {ECO:0000269|PubMed:25229427}.
uniprot
proteins