POLDIP2
entrez
26073
canonical
uniprot
Q9Y2S7
canonical
ensembl
ENSG00000004142
resolver
ensp
ENSP00000475924
resolver
ensp
ENSP00000477665
resolver
enst
ENST00000540200
resolver
enst
ENST00000618887
resolver
genesymbol
POLDIP2
resolver
genesymbol_syn
PDIP38
resolver
genesymbol_syn
POLD4
resolver
hgnc
HGNC:23781
resolver
uniprot
A0A087WT81
resolver
uniprot
A0ACM8QGA3
resolver
uniprot
B2R846
resolver
uniprot
B4DEM9
resolver
uniprot
Q96JE4
resolver
uniprot_entry
A0ACM8QGA3_HUMAN
resolver
uniprot_entry
B4DEM9_HUMAN
resolver
uniprot_entry
PDIP2_HUMAN
resolver
uniprot_sec
A0A087WT81
resolver
uniprot_sec
B2R846
resolver
uniprot_sec
Q96JE4
resolver
amino_acid_sequence
MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGKVLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
uniprot
proteins
function
FUNCTION: Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025). May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1) (PubMed:24191025, PubMed:26984527). {ECO:0000269|PubMed:24191025, ECO:0000269|PubMed:26984527}.
uniprot
proteins
mass_dalton
42033
uniprot
proteins
pubmed
11042152
uniprot
proteins
pubmed
12522211
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16428295
uniprot
proteins
pubmed
20554254
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24191025
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
26984527
uniprot
proteins
sequence_length
368
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000269|PubMed:16428295}. Nucleus {ECO:0000269|PubMed:16428295}. Note=Mainly localizes to the mitochondrial matrix; a small fraction localizes in the nucleus. {ECO:0000269|PubMed:16428295}.
uniprot
proteins