Fmo1
entrez
14261
canonical
uniprot
P50285
canonical
ensembl
ENSMUSG00000040181
resolver
ensp
ENSMUSP00000037259
resolver
ensp
ENSMUSP00000107143
resolver
ensp
ENSMUSP00000117398
resolver
ensp
ENSMUSP00000118534
resolver
ensp
ENSMUSP00000141210
resolver
ensp
ENSMUSP00000229992
resolver
ensp
ENSMUSP00000230004
resolver
ensp
ENSMUSP00000230005
resolver
enst
ENSMUST00000046049
resolver
enst
ENSMUST00000111518
resolver
enst
ENSMUST00000134098
resolver
genesymbol
Fmo1
resolver
genesymbol_syn
Fmo-1
resolver
uniprot
F6R899
resolver
uniprot
F7AN75
resolver
uniprot
Q3UNX7
resolver
uniprot
Q8C9C1
resolver
uniprot_entry
F6R899_MOUSE
resolver
uniprot_entry
F7AN75_MOUSE
resolver
uniprot_entry
FMO1_MOUSE
resolver
uniprot_entry
Q3UNX7_MOUSE
resolver
uniprot_entry
Q8C9C1_MOUSE
resolver
amino_acid_sequence
MVKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSSDLGGLWRFTEHVEEGRASLYKSVVSNSSREMSCYPDFPFPEDYPNFVPNSLFLEYLKLYSTQFNLQRCIYFNTKVCSITKRPDFAVSGQWEVVTVTNGKQNSAIFDAVMVCTGFLTNPHLPLDSFPGILTFKGEYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPIVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVFIKPSIKEVKENSVVFNNTPKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMVPTGETQARWVVQVLKGATTLPPPSVMMEEVNERKKNKHSGFGLCYCKALQTDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVKVTKTRTIQESPSSFETLLKLFSFLALLIAVFLIFL
uniprot
proteins
ec_number
1.14.13.148
uniprot
proteins
ec_number
1.14.13.8
uniprot
proteins
function
FUNCTION: Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics (PubMed:32156684, PubMed:9580872). Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes (PubMed:32156684). In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine (By similarity). {ECO:0000250|UniProtKB:P36365, ECO:0000269|PubMed:32156684, ECO:0000269|PubMed:9580872}.
uniprot
proteins
mass_dalton
59915
uniprot
proteins
protein_family
FMO family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
32156684
uniprot
proteins
pubmed
9580872
uniprot
proteins
sequence_length
532
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P36365}; Single-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 511..531; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins