Gpam
entrez
29653
canonical
uniprot
P97564
canonical
ensembl
ENSRNOG00000015124
resolver
ensp
ENSRNOP00000069320
resolver
ensp
ENSRNOP00000103828
resolver
enst
ENSRNOT00000083215
resolver
enst
ENSRNOT00000142012
resolver
genesymbol
Gpam
resolver
genesymbol_syn
Gpat1
resolver
uniprot
A0A0G2JV22
resolver
uniprot
A0ABK0LG87
resolver
uniprot
O35349
resolver
uniprot
P97565
resolver
uniprot
P97566
resolver
uniprot_entry
A0A0G2JV22_RAT
resolver
uniprot_entry
A0ABK0LG87_RAT
resolver
uniprot_entry
GPAT1_RAT
resolver
uniprot_sec
O35349
resolver
uniprot_sec
P97565
resolver
uniprot_sec
P97566
resolver
amino_acid_sequence
MEESSVTIGTIDVSYLPNSSEYSLGRCKHTNEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSITDNVLNSSRVQEAIAEVAAELNPDGSAQQQSKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDILYRALLHGHIVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLEGQSQKPVSAPLSLEQALLPAILPSRPDAAAAEHEDMSSNESRNAADEAFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSIYAVQNKRGSGGSAGGLGNLISQEQLVRKAASLCYLLSNEGTISLPCQTFYQVCQETVGKFIQYGILTVAEQDDQEDVSPGLAEQQWNKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQAKEHQQFITFLQRLLGPLLEAYSSAAIFVHTFRGPVPESEYLQKLHRYLLTRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRASVLELSTTFLPQGSRQKLLEYILSFVVL
uniprot
proteins
ec_number
2.3.1.15
uniprot
proteins
function
FUNCTION: Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids (PubMed:10446428, PubMed:22905194). Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid (PubMed:10446428, PubMed:22905194). Has a narrow hydrophobic binding cleft that selects for a linear acyl chain (By similarity). Catalytic activity is higher for substrates with a 16-carbon acyl chain (By similarity). {ECO:0000250|UniProtKB:Q9HCL2, ECO:0000269|PubMed:10446428, ECO:0000269|PubMed:22905194}.
uniprot
proteins
mass_dalton
93715
uniprot
proteins
pathway_participation
PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. {ECO:0000269|PubMed:10446428}.
uniprot
proteins
protein_family
GPAT/DAPAT family
uniprot
proteins
pubmed
10446428
uniprot
proteins
pubmed
10924502
uniprot
proteins
pubmed
16641100
uniprot
proteins
pubmed
22673903
uniprot
proteins
pubmed
22905194
uniprot
proteins
sequence_length
828
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000269|PubMed:10924502}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9HCL2}. Note=Associated with the mitochondrion outer membrane of hepatic cells via a patch of basic residues. {ECO:0000250|UniProtKB:Q9HCL2}.
uniprot
proteins