Baat
entrez
12012
canonical
uniprot
Q91X34
canonical
ensembl
ENSMUSG00000039653
resolver
ensp
ENSMUSP00000041983
resolver
ensp
ENSMUSP00000129603
resolver
enst
ENSMUST00000043056
resolver
enst
ENSMUST00000166036
resolver
genesymbol
Baat
resolver
uniprot
A2AKK7
resolver
uniprot
O08833
resolver
uniprot
Q8C1I3
resolver
uniprot_entry
BAAT_MOUSE
resolver
uniprot_sec
A2AKK7
resolver
uniprot_sec
O08833
resolver
uniprot_sec
Q8C1I3
resolver
amino_acid_sequence
MAKLTAVPLSALVDEPVHIQVTGLAPFQVVCLQASLKDEKGNLFSSQAFYRASEVGEVDLEHDPSLGGDYMGVHPMGLFWSLKPEKLLGRLIKRDVMNSPYQIHIKACHPYFPLQDIVVSPPLDSLTLERWYVAPGVKRIQVKESRIRGALFLPPGEGPFPGVIDLFGGAGGLMEFRASLLASRGFATLALAYWNYDDLPSRLEKVDLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLKQIRATVLINGPNFVSQSPHVYHGQVYPPVPSNEEFVVTNALGLVEFYRTFQETADKDSKYCFPIEKAHGHFLFVVGEDDKNLNSKVHANQAIAQLMKNGKKNWTLLSYPGAGHLIEPPYTPLCQASRMPILIPSLSWGGEVIPHAAAQEHSWKEIQKFLKQHLLPDLSSQL
uniprot
proteins
ec_number
2.3.1.65
uniprot
proteins
ec_number
3.1.2.2
uniprot
proteins
ec_number
3.1.2.27
uniprot
proteins
function
FUNCTION: Catalyzes the amidation of bile acids (BAs) with the amino acid taurine (PubMed:9215542). Selective for taurine conjugation of cholyl CoA and only taurine-conjugated BAs are found in bile (PubMed:9215542). Amidation of BAs in the liver with taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism (By similarity). This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption (By similarity). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids (By similarity). In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs (By similarity). {ECO:0000250|UniProtKB:Q14032, ECO:0000269|PubMed:9215542}.
uniprot
proteins
mass_dalton
46482
uniprot
proteins
protein_family
C/M/P thioester hydrolase family
uniprot
proteins
pubmed
12810727
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
9215542
uniprot
proteins
sequence_length
420
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q14032}. Peroxisome {ECO:0000250|UniProtKB:Q63276}.
uniprot
proteins