Mcm10
entrez
70024
canonical
uniprot
Q0VBD2
canonical
ensembl
ENSMUSG00000026669
resolver
ensp
ENSMUSP00000027980
resolver
ensp
ENSMUSP00000100050
resolver
ensp
ENSMUSP00000329895
resolver
enst
ENSMUST00000027980
resolver
enst
ENSMUST00000102985
resolver
genesymbol
Mcm10
resolver
uniprot
Q505F3
resolver
uniprot
Q8BMJ1
resolver
uniprot
Q8BYA7
resolver
uniprot_entry
MCM10_MOUSE
resolver
uniprot_sec
Q505F3
resolver
uniprot_sec
Q8BMJ1
resolver
uniprot_sec
Q8BYA7
resolver
amino_acid_sequence
MDVEEDDLCLLTSLLEENEAVLPCSSEKDKSLSLGDGDPDEFDELFDADGDGESYTEEAGSGEEGKTGNQEERLATLFGDVEDLTDDEVATSKVGNSGPPPAPSQEKTSEELQDELKKLQEQMKSLQEQLKAASIKQPPGTAPLQEPPDSSLQPLLKEKRIRRIQESACFSAELDVPTLPKAKRVARKPKTPAESSSRMRTPAQPLQVSSSFLEPNHSSSSRSSTPSPQAVPGNKCSRTIRNQNTVSPGNSGDRPQQVSQVSVEAFSGLRLRRPRVSSTEMSRKMAGRKLIRLPQIKEKMATENLEETDWVTFGVILRKVTPQSATSGQTFSIWKLNDLHDLTQCVSLFLFGDVHKDLWKTEQGTVIGLLNANPMKPKDGLKEVCLSIDHPQKVLIMGEAMDLGACKAKKKNGEPCTQTVNLHDCEYCQYHIQAQYKKLSAKRTDLQSTFSGGRIPKKFRKGTSLKERLCQDGFYYGGVSSESFAASRAAAIAPKKKVQTTLTNLVVRGTNSIIQETKQKLGIPQKSLSCSEEFRELMALPTFGARNLQKHLARAKASGSSKPAIQSISASALLKQQKQQMLEMRKRRSEDIQKRFLQSSSEVQSPAVPSSSRQAAAQSPRTGAEFPRLEGTATPRMPKLGRGISEGDDVLFFDDSPPPRPKLSAAAEAKKLAAIAKLRAKGQILTKVDPNNTVRKQMDGRAMLGVKERVENSNTVSPEEELEPARKKRREQLAYLESEEFQKILKAKSKHTDILKEAEAELQKSYFEPLVKKEQMEEKMRATREVKCRVVTCRTCTYTHFKPLETCVSEQHNLHWHDGVKRFFKCPCGNRTISLDKLPNKHCRNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
uniprot
proteins
function
FUNCTION: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 (By similarity). {ECO:0000250|UniProtKB:Q7L590}.
uniprot
proteins
mass_dalton
98406
uniprot
proteins
protein_family
MCM10 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
885
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q7L590}. Note=Colocalizes with ORC2 in nuclei foci. Associated with chromatin in S phase (By similarity). {ECO:0000250|UniProtKB:Q7L590}.
uniprot
proteins