SPIC
entrez
121599
canonical
uniprot
Q8N5J4
canonical
ensembl
ENSG00000166211
resolver
ensp
ENSP00000448580
resolver
ensp
ENSP00000771964
resolver
enst
ENST00000551346
resolver
genesymbol
SPIC
resolver
hgnc
HGNC:29549
resolver
uniprot_entry
SPIC_HUMAN
resolver
amino_acid_sequence
MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTEEPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
uniprot
proteins
function
FUNCTION: Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
29180
uniprot
proteins
protein_family
ETS family
uniprot
proteins
pubmed
12459275
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
248
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins