STRIP1
entrez
85369
canonical
uniprot
Q5VSL9
canonical
ensembl
ENSG00000143093
resolver
ensp
ENSP00000358810
resolver
ensp
ENSP00000358811
resolver
ensp
ENSP00000741058
resolver
genesymbol
STRIP1
resolver
genesymbol_syn
FAM40A
resolver
genesymbol_syn
KIAA1761
resolver
hgnc
HGNC:25916
resolver
uniprot
Q0V925
resolver
uniprot
Q5VSL8
resolver
uniprot
Q658K2
resolver
uniprot
Q6ZV31
resolver
uniprot
Q8N598
resolver
uniprot
Q96SN2
resolver
uniprot
Q9C0A2
resolver
uniprot_entry
STRP1_HUMAN
resolver
uniprot_sec
Q0V925
resolver
uniprot_sec
Q5VSL8
resolver
uniprot_sec
Q658K2
resolver
uniprot_sec
Q6ZV31
resolver
uniprot_sec
Q8N598
resolver
uniprot_sec
Q96SN2
resolver
uniprot_sec
Q9C0A2
resolver
amino_acid_sequence
MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ
uniprot
proteins
function
FUNCTION: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation. {ECO:0000269|PubMed:18782753, ECO:0000269|PubMed:21834987, ECO:0000269|PubMed:30622739, ECO:0000269|PubMed:33633399}.
uniprot
proteins
mass_dalton
95576
uniprot
proteins
mutagenesis
MUTAGEN 131..134; /note="DGLE->EGLK: Decreased formation of STRIPAK core complex."; /evidence="ECO:0000269|PubMed:33633399"; MUTAGEN 427; /note="K->E: Decreased interaction with other STRIPAK core complex components. Decreased inhibition of Hippo signaling."; /evidence="ECO:0000269|PubMed:33633399"; MUTAGEN 744; /note="R->E: Decreased interaction with other STRIPAK core complex components. Decreased inhibition of Hippo signaling."; /evidence="ECO:0000269|PubMed:33633399
uniprot
proteins
protein_family
STRIP family
uniprot
proteins
pubmed
11214970
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
18691976
uniprot
proteins
pubmed
18782753
uniprot
proteins
pubmed
19367720
uniprot
proteins
pubmed
19369195
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
21834987
uniprot
proteins
pubmed
22223895
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25743393
uniprot
proteins
pubmed
26566883
uniprot
proteins
pubmed
30622739
uniprot
proteins
pubmed
33633399
uniprot
proteins
sequence_length
837
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:21834987}. Note=Enriched on the plasma membrane.
uniprot
proteins