AMIGO2
entrez
347902
canonical
uniprot
Q86SJ2
canonical
ensembl
ENSG00000139211
resolver
ensp
ENSP00000266581
resolver
ensp
ENSP00000406020
resolver
ensp
ENSP00000449034
resolver
ensp
ENSP00000542280
resolver
ensp
ENSP00000542281
resolver
ensp
ENSP00000542282
resolver
ensp
ENSP00000542283
resolver
ensp
ENSP00000542284
resolver
ensp
ENSP00000542285
resolver
ensp
ENSP00000632975
resolver
ensp
ENSP00000632976
resolver
ensp
ENSP00000632977
resolver
enst
ENST00000266581
resolver
enst
ENST00000429635
resolver
enst
ENST00000550413
resolver
enst
ENST00000872221
resolver
enst
ENST00000872222
resolver
enst
ENST00000872223
resolver
enst
ENST00000872224
resolver
enst
ENST00000872225
resolver
enst
ENST00000872226
resolver
enst
ENST00000962916
resolver
enst
ENST00000962917
resolver
enst
ENST00000962918
resolver
genesymbol
AMIGO2
resolver
genesymbol_syn
ALI1
resolver
hgnc
HGNC:24073
resolver
uniprot
Q4VBP6
resolver
uniprot
Q7Z4A0
resolver
uniprot
Q96CN8
resolver
uniprot_entry
AMGO2_HUMAN
resolver
uniprot_sec
Q4VBP6
resolver
uniprot_sec
Q7Z4A0
resolver
uniprot_sec
Q96CN8
resolver
amino_acid_sequence
MSLRVHTLPTLLGAVVRPGCRELLCLLMITVTVGPGASGVCPTACICATDIVSCTNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQFPMDLYVGRFKLAELMFLDVSYNRIPSMPMHHINLVPGKQLRGIYLHGNPFVCDCSLYSLLVFWYRRHFSSVMDFKNDYTCRLWSDSRHSRQVLLLQDSFMNCSDSIINGSFRALGFIHEAQVGERLMVHCDSKTGNANTDFIWVGPDNRLLEPDKEMENFYVFHNGSLVIESPRFEDAGVYSCIAMNKQRLLNETVDVTINVSNFTVSRSHAHEAFNTAFTTLAACVASIVLVLLYLYLTPCPCKCKTKRQKNMLHQSNAHSSILSPGPASDASADERKAGAGKRVVFLEPLKDTAAGQNGKVRLFPSEAVIAEGILKSTRGKSDSDSVNSVFSDTPFVAST
uniprot
proteins
function
FUNCTION: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
uniprot
proteins
mass_dalton
57934
uniprot
proteins
protein_family
AMIGO family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12629050
uniprot
proteins
pubmed
12843293
uniprot
proteins
pubmed
15107827
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
522
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity). {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 399..419; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins