Grm8
entrez
14823
canonical
uniprot
P47743
canonical
ensembl
ENSMUSG00000024211
resolver
ensp
ENSMUSP00000087998
resolver
ensp
ENSMUSP00000110978
resolver
ensp
ENSMUSP00000110979
resolver
enst
ENSMUST00000090512
resolver
enst
ENSMUST00000115323
resolver
enst
ENSMUST00000115324
resolver
genesymbol
Grm8
resolver
genesymbol_syn
Gprc1h
resolver
genesymbol_syn
Mglur8
resolver
uniprot
B7ZMR4
resolver
uniprot
F7AS91
resolver
uniprot
Q05BD6
resolver
uniprot
Q6B964
resolver
uniprot_entry
B7ZMR4_MOUSE
resolver
uniprot_entry
F7AS91_MOUSE
resolver
uniprot_entry
GRM8_MOUSE
resolver
uniprot_entry
Q05BD6_MOUSE
resolver
uniprot_sec
Q6B964
resolver
amino_acid_sequence
MVCEGKRSTSCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRLDGDIILGGLFPVHAKGERGVPCGDLKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKELCPGYIGLCPRMVTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEYKIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTYISYSNHSI
uniprot
proteins
function
FUNCTION: G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
uniprot
proteins
mass_dalton
101828
uniprot
proteins
mutagenesis
MUTAGEN 868; /note="K->R: No change in sumoylation. Abolishes sumoylation; when associated with R-872 and R-882."; /evidence="ECO:0000269|PubMed:16144832"; MUTAGEN 872; /note="K->R: No change in sumoylation. Abolishes sumoylation; when associated with R-868 and R-882."; /evidence="ECO:0000269|PubMed:16144832"; MUTAGEN 882; /note="K->R: Abolishes sumoylation. Abolishes sumoylation; when associated with R-868 and R-872."; /evidence="ECO:0000269|PubMed:16144832
uniprot
proteins
protein_family
G protein-coupled receptor 3 family
uniprot
proteins
pubmed
15755905
uniprot
proteins
pubmed
16144832
uniprot
proteins
pubmed
7722646
uniprot
proteins
sequence_length
908
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 584..608; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 621..641; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 648..668; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 696..716; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 747..768; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 782..803; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 819..843; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins