B3GNT7
entrez
93010
canonical
uniprot
Q8NFL0
canonical
ensembl
ENSG00000156966
resolver
ensp
ENSP00000287590
resolver
enst
ENST00000287590
resolver
genesymbol
B3GNT7
resolver
hgnc
HGNC:18811
resolver
uniprot
B3KWY4
resolver
uniprot
B7WNP0
resolver
uniprot_entry
B3GN7_HUMAN
resolver
uniprot_sec
B3KWY4
resolver
uniprot_sec
B7WNP0
resolver
amino_acid_sequence
MSLWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNNFWKNPKDVAAPTPMASQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYFPMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTASKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNLLEFLADRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGISRNRNSRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHSNLTCSRKLQVL
uniprot
proteins
ec_number
2.4.1.-
uniprot
proteins
function
FUNCTION: N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer (PubMed:14706853, PubMed:17690104). Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (By similarity) (PubMed:17690104). May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (By similarity). {ECO:0000250|UniProtKB:Q8K0J2, ECO:0000269|PubMed:14706853, ECO:0000269|PubMed:17690104}.
uniprot
proteins
mass_dalton
45987
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein glycosylation. {ECO:0000305|PubMed:14706853, ECO:0000305|PubMed:17690104}.
uniprot
proteins
protein_family
Glycosyltransferase 31 family
uniprot
proteins
pubmed
12061784
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
14706853
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
17690104
uniprot
proteins
sequence_length
401
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..26; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins