Scara5
entrez
71145
canonical
uniprot
Q8K299
canonical
ensembl
ENSMUSG00000022032
resolver
ensp
ENSMUSP00000022610
resolver
ensp
ENSMUSP00000063391
resolver
genesymbol
Scara5
resolver
uniprot
Q8BZZ2
resolver
uniprot
Q8R330
resolver
uniprot
Q91WD6
resolver
uniprot
Q9CUC3
resolver
uniprot
Q9D4G8
resolver
uniprot_entry
SCAR5_MOUSE
resolver
uniprot_sec
Q8BZZ2
resolver
uniprot_sec
Q8R330
resolver
uniprot_sec
Q91WD6
resolver
uniprot_sec
Q9CUC3
resolver
uniprot_sec
Q9D4G8
resolver
amino_acid_sequence
MDNKAMYLHTVSDRDNGSIFEEPFDGRSLSKLNLCEDGPCHKRRAGGCCTQLGSLSALKHAVLGLYLLVFLILVGIFILAVSRPRSSPDDLKALTRNVNRLNESLRDMQLRLLQAPLQADLTEQVWKVQDALQNQTDSLLALAGLVQRLEGTLWGLHAQAAQTEQAMALLRDRTGQQSDSAQLELYQLQVESNRSQLLLQRHAGLLDGLARRVGVLGEELADVGGALRGLNHSLSYDVALHSTWLQDLQVLVSNASADTRRMRLVHMDMEMQLKQELATLNVVTEDLRLKDWEHSIALRNITLAKGPPGPKGDQGNEGKEGKPGSPGLPGSRGLPGERGDPGLPGPKGDDGKLGATGPMGMRGFKGDRGPKGEKGERGERAGDMDFTMIRLVNGSGPHQGRVEVFHDRRWGTVCDDGWDKKDGDVVCRMLGFHGVEEVYRTARFGQGTGRIWMDDVNCKGTESSIFHCQFSKWGVTNCGHAEDAGVTCTVP
uniprot
proteins
function
FUNCTION: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1). {ECO:0000255|HAMAP-Rule:MF_03070, ECO:0000269|PubMed:19154717}.
uniprot
proteins
mass_dalton
53667
uniprot
proteins
protein_family
SCARA5 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16407294
uniprot
proteins
pubmed
19154717
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
491
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_03070, ECO:0000269|PubMed:19154717}; Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_03070, ECO:0000269|PubMed:19154717}.
uniprot
proteins
transmembrane_region
TRANSMEM 61..81; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255|HAMAP-Rule:MF_03070
uniprot
proteins