Lrrc14
entrez
500900
canonical
uniprot
Q569B5
canonical
ensembl
ENSRNOG00000016128
resolver
ensembl
ENSRNOG00065030366
resolver
ensp
ENSRNOP00000069176
resolver
ensp
ENSRNOP00000083734
resolver
ensp
ENSRNOP00000098700
resolver
ensp
ENSRNOP00065043071
resolver
enst
ENSRNOT00000077562
resolver
enst
ENSRNOT00000097197
resolver
enst
ENSRNOT00000173835
resolver
enst
ENSRNOT00065052378
resolver
genesymbol
Lrrc14
resolver
uniprot
A0A0G2JUP6
resolver
uniprot
A0A8I5ZZT2
resolver
uniprot
A0ABK0KWH6
resolver
uniprot_entry
A0A0G2JUP6_RAT
resolver
uniprot_entry
A0A8I5ZZT2_RAT
resolver
uniprot_entry
A0ABK0KWH6_RAT
resolver
uniprot_entry
LRC14_RAT
resolver
amino_acid_sequence
MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTAVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERLSTESMQAVILGLTARIHAREAEAGTQPVCRKHTLRVLDMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQVGTAKPGLSPVPVEIRVDLRVNRASYTFLREALQSSVDSLLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRIDLRFNNLGLRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFICLRELSIGSSLLSGRLDQLLSTLQRPLESLELAFCALLPEDLRFLAQSSHAAHLKKLDLSGNDLSGNQLTPFQGLLQAVAATLLHLELTECQIADAQLLATLPTLTRCASLRYLGLYGNPLSMAGLKELLRDSVIQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFNL
uniprot
proteins
function
FUNCTION: Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB. {ECO:0000250|UniProtKB:Q15048}.
uniprot
proteins
mass_dalton
54915
uniprot
proteins
protein_family
LRRC14 subfamily
uniprot
proteins
protein_family
PRAME family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
493
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q15048}.
uniprot
proteins