NOP14
entrez
8602
canonical
uniprot
P78316
canonical
ensembl
ENSG00000087269
resolver
ensp
ENSP00000315674
resolver
ensp
ENSP00000381146
resolver
ensp
ENSP00000405068
resolver
ensp
ENSP00000717060
resolver
genesymbol
NOP14
resolver
genesymbol_syn
C4orf9
resolver
genesymbol_syn
NOL14
resolver
hgnc
HGNC:16821
resolver
uniprot
A8KA74
resolver
uniprot
D3DVR6
resolver
uniprot
Q7LGI5
resolver
uniprot
Q7Z6K0
resolver
uniprot
Q8TBR6
resolver
uniprot_entry
A8KA74_HUMAN
resolver
uniprot_entry
NOP14_HUMAN
resolver
uniprot_sec
D3DVR6
resolver
uniprot_sec
Q7LGI5
resolver
uniprot_sec
Q7Z6K0
resolver
uniprot_sec
Q8TBR6
resolver
amino_acid_sequence
MAKAKKVGARRKASGAPAGARGGPAKANSNPFEVKVNRQKFQILGRKTRHDVGLPGVSRARALRKRTQTLLKEYKERDKSNVFRDKRFGEYNSNMSPEEKMMKRFALEQQRHHEKKSIYNLNEDEELTHYGQSLADIEKHNDIVDSDSDAEDRGTLSAELTAAHFGGGGGLLHKKTQQEGEEREKPKSRKELIEELIAKSKQEKRERQAQREDALELTEKLDQDWKEIQTLLSHKTPKSENRDKKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEAELAKEEQEHLRKLEAERLRRMLGKDEDENVKKPKHMSADDLNDGFVLDKDDRRLLSYKDGKMNVEEDVQEEQSKEASDPESNEEEGDSSGGEDTEESDSPDSHLDLESNVESEEENEKPAKEQRQTPGKGLISGKERAGKATRDELPYTFAAPESYEELRSLLLGRSMEEQLLVVERIQKCNHPSLAEGNKAKLEKLFGFLLEYVGDLATDDPPDLTVIDKLVVHLYHLCQMFPESASDAIKFVLRDAMHEMEEMIETKGRAALPGLDVLIYLKITGLLFPTSDFWHPVVTPALVCLSQLLTKCPILSLQDVVKGLFVCCLFLEYVALSQRFIPELINFLLGILYIATPNKASQGSTLVHPFRALGKNSELLVVSAREDVATWQQSSLSLRWASRLRAPTSTEANHIRLSCLAVGLALLKRCVLMYGSLPSFHAIMGPLQALLTDHLADCSHPQELQELCQSTLTEMESQKQLCRPLTCEKSKPVPLKLFTPRLVKVLEFGRKQGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK
uniprot
proteins
function
FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit (PubMed:34516797). During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity). Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity). Ensures correct nucleolar localization of small ribosomal subunit processome member EMG1 as part of a complex with NOC4L and UTP14A (PubMed:27798105). {ECO:0000250|UniProtKB:Q99207, ECO:0000269|PubMed:27798105, ECO:0000269|PubMed:34516797}.
uniprot
proteins
mass_dalton
97668
uniprot
proteins
protein_family
NOP14 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18318008
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
27798105
uniprot
proteins
pubmed
34516797
uniprot
proteins
pubmed
9661704
uniprot
proteins
pubmed
9734812
uniprot
proteins
sequence_length
857
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:27798105}.
uniprot
proteins