RGN
entrez
9104
canonical
uniprot
Q15493
canonical
ensembl
ENSG00000130988
resolver
ensp
ENSP00000253303
resolver
ensp
ENSP00000380365
resolver
ensp
ENSP00000406568
resolver
ensp
ENSP00000595527
resolver
genesymbol
HEL-S-41
resolver
genesymbol
RGN
resolver
genesymbol_syn
SMP30
resolver
hgnc
HGNC:9989
resolver
uniprot
A4FTW1
resolver
uniprot
A8K271
resolver
uniprot
Q53FC9
resolver
uniprot
Q5JRR5
resolver
uniprot
V9HWF8
resolver
uniprot_entry
RGN_HUMAN
resolver
uniprot_entry
V9HWF8_HUMAN
resolver
uniprot_sec
A4FTW1
resolver
uniprot_sec
A8K271
resolver
uniprot_sec
Q53FC9
resolver
uniprot_sec
Q5JRR5
resolver
amino_acid_sequence
MSSIKIECVLPENCRCGESPVWEEVSNSLLFVDIPAKKVCRWDSFTKQVQRVTMDAPVSSVALRQSGGYVATIGTKFCALNWKEQSAVVLATVDNDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGALYSLFPDHHVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYSVDAFDYDLQTGQISNRRSVYKLEKEEQIPDGMCIDAEGKLWVACYNGGRVIRLDPVTGKRLQTVKLPVDKTTSCCFGGKNYSEMYVTCARDGMDPEGLLRQPEAGGIFKITGLGVKGIAPYSYAG
uniprot
proteins
ec_number
3.1.1.17
uniprot
proteins
function
FUNCTION: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
33253
uniprot
proteins
mutagenesis
MUTAGEN 18; /note="E->A: Reduces enzyme activity by about 90%."; /evidence="ECO:0000269|PubMed:20329768"; MUTAGEN 103; /note="N->A: Reduces enzyme activity by about 95%."; /evidence="ECO:0000269|PubMed:20329768"; MUTAGEN 154; /note="N->A: Reduces enzyme activity by about 95%."; /evidence="ECO:0000269|PubMed:20329768"; MUTAGEN 204; /note="D->A: Reduces enzyme activity by over 98%."; /evidence="ECO:0000269|PubMed:20329768
uniprot
proteins
protein_family
SMP-30/CGR1 family
uniprot
proteins
pubmed
10677570
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
pubmed
20329768
uniprot
proteins
pubmed
23349732
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
7548213
uniprot
proteins
sequence_length
299
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
uniprot
proteins