A0A1B0GRQ3
uniprot
A0A1B0GRQ3
canonical
amino_acid_sequence
MEELRRGLSRWKRYHIKVHLADEALLLPLTVRPRDTLSDLRAQLVGQGVSSWRRTFYYNSRPLPDHQTVREARLQDGSVLLLLSDTR
uniprot
proteins
function
FUNCTION: Promotes epithelial differentiation by enhancing the sumoylation and activation of CDC42 (By similarity). Promotes keratinocyte proliferation (PubMed:34351912). This contributes to the maintenance of skin homeostasis by enhancing wound healing after skin injury (PubMed:34351912). Acts as a tumor suppressor in epithelial tumors (PubMed:36899004). {ECO:0000250|UniProtKB:A0A2R8Y7D0, ECO:0000269|PubMed:34351912, ECO:0000269|PubMed:36899004}.
uniprot
proteins
mass_dalton
10225
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
34351912
uniprot
proteins
pubmed
36369429
uniprot
proteins
pubmed
36899004
uniprot
proteins
sequence_length
87
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:A0A2R8Y7D0}. Cell junction {ECO:0000250|UniProtKB:A0A2R8Y7D0}. Cytoplasm {ECO:0000269|PubMed:34351912}.
uniprot
proteins