Mto1
entrez
68291
canonical
uniprot
Q923Z3
canonical
ensembl
ENSMUSG00000032342
resolver
ensp
ENSMUSP00000034896
resolver
enst
ENSMUST00000034896
resolver
genesymbol
Mto1
resolver
uniprot
G5E889
resolver
uniprot
Q9D2Q5
resolver
uniprot_entry
G5E889_MOUSE
resolver
uniprot_entry
MTO1_MOUSE
resolver
uniprot_sec
Q9D2Q5
resolver
amino_acid_sequence
MFLLRGRGHWAAASLGRRLPLRRLRSDSAAPCTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILSTPLLTVQKGAVEDLVLAEPEPGYPGKSRVRGVVLADGSTIYAESVILTTGTFLRGMIIIGLEMHPAGRLGDQPSIGLAQTLEKLGFMVGRLKTGTPPRLGKESINFSILNKHTPDDPSIPFSFLSDSVWIKPEDQLPCYLTHTNPRVDAIVLENLHLNSHVQETTKGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHPGYGVQYDYLDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHKEAGCVSSQRFERALWMKSSLEEGISVLKSIKFSSSKWKKLIPQIPISINRSLPVSALDVLKYEEVDMESLVGVLPEPLEKYTACRELARRLKIEASYESVLSYQLQEIKEVQQDEALQLPHELDYLTIRDVSLSQEVREKLHLSRPQTIGAASRIPGVTPAAIINLLRFVRSTRQSRQQ
uniprot
proteins
function
FUNCTION: Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity. {ECO:0000250|UniProtKB:Q9Y2Z2}.
uniprot
proteins
mass_dalton
74332
uniprot
proteins
protein_family
MnmG family
uniprot
proteins
pubmed
14522080
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
669
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:14522080}.
uniprot
proteins