Pmfbp1
entrez
56523
canonical
uniprot
Q9WVQ0
canonical
ensembl
ENSMUSG00000031727
resolver
ensp
ENSMUSP00000034162
resolver
enst
ENSMUST00000034162
resolver
genesymbol
Pmfbp1
resolver
genesymbol_syn
Stap
resolver
uniprot
B2RR67
resolver
uniprot_entry
B2RR67_MOUSE
resolver
uniprot_entry
PMFBP_MOUSE
resolver
amino_acid_sequence
MLKLKGELRTAKGLKNEAGERDRDVSNLNSKLLSLQLDIKNLHDVCKRQGKTLQENQLCVEEAMLKANHNKKQAQTLVFTDNQMDFRVNKQYHLRQLQQLKKKLLTLQQELEFRTQELQASYCSLLQYQSILEKQTSDLLVLHRHCKLKEDEVILYEEEMGNHSKSTGEKLHLAQEQLALAGDKILSLERSLNLYRDKYQTSLSNIELLECQVKMLEGELSGLIGQDPENKGDHPKVRIYTSPCVIQEHQETLKRLSEVWQKVSEQDDLIQELRNKLACSNSLVLEREEALIKLQAEFASYTATHRHPPTSSEDCEDITKILKHLQEQKDSQCLHVEEYQNLVKDLRMELEAVSEQKKKIMKDMMKLELDLHGLREETSCVIEKKDKETVFLQYRLQDLQQQYTESQKLSLKKDKLLQDKDERLHELEKNLMQVQNSLREKEAELEKLQCTTKELDTSLQEARQSTSKIDCEALRAEIQKLKDSLEEAREQLKVSDQNLTQSKEEAHLSASSLEDAHRKIENCLLQDKQKEEVIKDLQSQLHKLQKESSKIEEERKHNRQRLQELSSELSEGQRRLSNAEKEKSLLQKTLDEDEKKIDELFHSTQVSEQKQRELTNSIRKLEEELLEIKGLLEEKREQLKKSKEQEKALEEEIEALRQEAKRKEKMAKEHLRKLDEEKENLQAELTSRSSHLDSSLNKYNSSQKVIQELNAEIARQKDSIMILQTQLDSAIQKEKNCFQNMVSKEAYEELVRKSGNCQDDLTQALEKLTQATSETKSLNRSLQQTQERKAQLEDEIAAYEERMKKLNMELKKLQGFQQQSEQEVHNFDKKLEEMSNQVLQWQRQHQSDLKMLAAKESQLREFQEEMATLRESLLADEKEPYSPPAKLTPKETCRHHRENDQIMNNVEQWAKEQKIANEKLGNKLREQVKYIAKLTGEKDHLHNVMVHLQQENKKLKNEIEEKKLKAGNPRICVKAFPPNKLEPSQKGKLCCALGWRGIPQDLTPKTDHKYMGLPHSSGSSYC
uniprot
proteins
function
FUNCTION: Required for normal spermatogenesis (PubMed:30032984, PubMed:30298696). It functions as a scaffold protein that attaches the sperm head-tail connecting piece to the nuclear envelope, thus maintaining sperm head and tail integrity (PubMed:30032984). May also be involved in the general organization of cellular cytoskeleton. {ECO:0000269|PubMed:11468771, ECO:0000269|PubMed:30032984, ECO:0000269|PubMed:30298696}.
uniprot
proteins
mass_dalton
119401
uniprot
proteins
pubmed
11468771
uniprot
proteins
pubmed
30032984
uniprot
proteins
pubmed
30298696
uniprot
proteins
sequence_length
1022
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000269|PubMed:11468771, ECO:0000269|PubMed:30032984, ECO:0000269|PubMed:30298696}. Note=Localized at the sperm head-tail connecting piece (PubMed:30032984, PubMed:30298696). During spermatogenesis, it is first observed in the cytoplasm of round spermatids, it later appears in the implantation fossa region of the sperm nucleus during sperm head elongation and differentiation, and finally it localizes to the head-tail connecting piece (PubMed:30032984). {ECO:0000269|PubMed:30032984, ECO:0000269|PubMed:30298696}.
uniprot
proteins