Amacr
entrez
17117
canonical
uniprot
O09174
canonical
ensembl
ENSMUSG00000022244
resolver
ensp
ENSMUSP00000066915
resolver
enst
ENSMUST00000070877
resolver
genesymbol
Amacr
resolver
genesymbol_syn
Macr1
resolver
uniprot
Q543Q9
resolver
uniprot
Q9DCW6
resolver
uniprot_entry
AMACR_MOUSE
resolver
uniprot_sec
Q543Q9
resolver
uniprot_sec
Q9DCW6
resolver
amino_acid_sequence
MVLRGVRVVELAGLAPGPFCGMVLADFGAEVVRVNRLGSTGENFLARGKRSLALDLKRSQGVTVLRRMCARADVLLEPFRCGVMEKLQLGPETLLQDNPKLIYARLSGFGQSGIFSKVAGHDINYLALSGVLSKIGRSGENPYPPLNLLADFGGGGLMCTLGIVLALFERTRSGRGQVIDSSMVEGTAYLSSFLWKTQPMGLWKQPRGQNILDGGAPFYTTYKTADGEFMAVGAIEPQFYALLLKGLGLESEELPSQMSSADWPEMKKKFADVFAKKTKAEWCQIFDGTDACVTPVLTFEEALHHQHNRERASFITDGEQLPSPRPAPLLSRTPAVPSAKRDPSVGEHTVEVLREYGFSQEEILQLHSDRIVESDKLKANL
uniprot
proteins
ec_number
5.1.99.4
uniprot
proteins
function
FUNCTION: Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters (By similarity). Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs (By similarity). {ECO:0000250|UniProtKB:Q9UHK6}.
uniprot
proteins
mass_dalton
41704
uniprot
proteins
pathway_participation
PATHWAY: Lipid metabolism; bile acid biosynthesis.; PATHWAY: Lipid metabolism; fatty acid metabolism.
uniprot
proteins
protein_family
CoA-transferase III family
uniprot
proteins
pubmed
10770938
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
23806337
uniprot
proteins
pubmed
9307041
uniprot
proteins
sequence_length
381
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Peroxisome {ECO:0000269|PubMed:10770938}. Mitochondrion {ECO:0000269|PubMed:10770938}.
uniprot
proteins