Adamtsl4
entrez
310670
canonical
uniprot
Q4FZU4
canonical
ensembl
ENSRNOG00000049385
resolver
ensembl
ENSRNOG00055031628
resolver
ensembl
ENSRNOG00060013233
resolver
ensembl
ENSRNOG00065023504
resolver
ensp
ENSRNOP00000063998
resolver
ensp
ENSRNOP00055045275
resolver
ensp
ENSRNOP00060017878
resolver
ensp
ENSRNOP00065032702
resolver
enst
ENSRNOT00000074156
resolver
enst
ENSRNOT00055054782
resolver
enst
ENSRNOT00060022557
resolver
enst
ENSRNOT00065040198
resolver
genesymbol
Adamtsl4
resolver
uniprot_entry
ATL4_RAT
resolver
amino_acid_sequence
MELWLGRLWLYVMLLLLLLQLCQDQELLGPSLQTPSEEDQVPEGLWGPWGRWASCSQPCGVGVQRRSRTCELHPALSLPPRPPRHPEAPQPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPGMFGYGRVPFALPLHRSRRLAHKPGQPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRTSSAPSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQLSRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTPECSGESEQMRACSQEPCPPEQPDPRALQCAAFDSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGSLDICVAGHCLSPGCDGILGSGRRPDGCGVCGGDGSTCRLVSGNLTDRGGPLGYQKILWIPAGASHLRISQFRPSSNYLALRGPGGRSIINGNWAVDPPGSYAAVGTVFQYNRPPREEGKGETLSAEGPTTQPVDVYMIFQEDNPGVFYQYVTSAAPESPSTMPPALQLQPEMLRGEPLLPSAPRPVRAPGTLQRQARIPQVPPPTHVRTAMGSSAGYWKQVGHSECSASCGKGVWRPIFLCVSRESGEELDEQSCAVGARPPASPESCHRPPCPPYWEAGEWTSCSRSCGPGTQHRQLLCRQEFGGGGSSVPPERCGHLPRPNITQSCQLRLCGHWEISSPWSQCSVRCGRGQRSRQVRCVGSNGHEVGKQECASGPPPPPSREACDMGPCTTAWFYSDWSSKCSAECGTGIQRRAVVCLRSGETLQGDPEAGSTEQGCPLRSRPPDMRACSLGPCEKTWRWYTGPWSECSSECGSGTQHRDIICVSKLGTKFNVTSPSNCSHLPRPPALQPCQGQACEDQWFSTLWSPCSQSCQGGVQTREVQCLSSNHTLSSRCPPHLRPSRKRPCNSQPCNQRPDDQCKDSSPHCPLVVQARLCVYPYYTATCCRSCAHVLEQSQLEPA
uniprot
proteins
function
FUNCTION: Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
112785
uniprot
proteins
post_translational_modification
PTM: Glycosylated (By similarity). Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion (By similarity). {ECO:0000250}.
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
1030
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Colocalizes with FMN1 microfibrils in the eye ECM. {ECO:0000250}.
uniprot
proteins