SPACA4
entrez
171169
canonical
uniprot
Q8TDM5
canonical
ensembl
ENSG00000177202
resolver
ensp
ENSP00000312774
resolver
enst
ENST00000321762
resolver
genesymbol
SPACA4
resolver
genesymbol_syn
SAMP14
resolver
hgnc
HGNC:16441
resolver
uniprot
A0A140VJU1
resolver
uniprot_entry
A0A140VJU1_HUMAN
resolver
uniprot_entry
SACA4_HUMAN
resolver
amino_acid_sequence
MVLCWLLLLVMALPPGTTGVKDCVFCELTDSMQCPGTYMHCGDDEDCFTGHGVAPGTGPVINKGCLRATSCGLEEPVSYRGVTYSLTTNCCTGRLCNRAPSSQTVGATTSLALGLGMLLPPRLL
uniprot
proteins
function
FUNCTION: Sperm surface membrane protein that is essential for effective sperm-zona pellucida binding and penetration during fertilization. {ECO:0000269|PubMed:12788941, ECO:0000269|PubMed:37377732}.
uniprot
proteins
mass_dalton
13004
uniprot
proteins
protein_family
SPACA4/bouncer family
uniprot
proteins
pubmed
12788941
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
37377732
uniprot
proteins
sequence_length
124
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12788941}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:12788941}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:12788941}. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane {ECO:0000269|PubMed:37377732}. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane {ECO:0000269|PubMed:37377732}. Note=Expressed in acrosomal matrix and outer and inner acrosomal membranes. {ECO:0000269|PubMed:12788941, ECO:0000269|PubMed:37377732}.
uniprot
proteins