Rasa2
entrez
114713
canonical
uniprot
P58069
canonical
ensembl
ENSMUSG00000032413
resolver
ensp
ENSMUSP00000034984
resolver
ensp
ENSMUSP00000275746
resolver
ensp
ENSMUSP00000345578
resolver
enst
ENSMUST00000034984
resolver
genesymbol
Rasa2
resolver
uniprot
G3X918
resolver
uniprot_entry
RASA2_MOUSE
resolver
uniprot_sec
G3X918
resolver
amino_acid_sequence
MAAAAPAAAASPEAPAVSGSADPETGDEDSREVRVLQSLRGRIYEAKNLLPYLGPNKMRDCFCTINLDQEEVYRTQVVEKSLSPYFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCSHSGKETWFSLQPIDSNSEVQGKVHLELRLNELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEVFYFEVTRSSSYSRKSQFQVEEEDIEKLEIRIDLWNNENLVQDVFLGEIKVPVNVLRSDSFHQAWYLLQPRDNGNKSSKTDDLGSLLLTLCYTEDCVLPSEYYGPLKTLLLKSPDVQPVSASAAYILGEICQDQKDAVLPLVRLLLHHNKLVPFITAVAELDLKDTPDANAIFRGNSLATQCLTEMMKIVGGHYLKVTLKPVLDEICESSKSCEIDPVKLKEGDNVENNKENLYYYVDKVFNTIVGSSVSCPTVMCDIFYSLRQMAAKKFPNHPHVQYSAVSSFVFLRFFAVAILSPHAFHLRPHYPDTQTVRTLTLISKTIQIIGNWGCQSRKKSRFKKSVMCEFLKMFQEERYFTDVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHRQQGKDAIYTIPVKNILAVEKLEEGSFNKKNMFQVIHTEKTLYIQANNCVEANEWIDVLCRVSRCNHNRLSSFHPSAYLNGNWLCCQETSESTPGCKPCTAGIPADIQIDIDEDRETERIYSIFTLSLLKLQKMEETCGSIAVYQGPQKEPGYSKFTIEDSVATFKTIQQIKSTIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKIS
uniprot
proteins
function
FUNCTION: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) and phospholipids.
uniprot
proteins
mass_dalton
96401
uniprot
proteins
mutagenesis
MUTAGEN 626..628; /note="KKR->QQQ: No binding to IP4, reduced binding to phospholipids."; /evidence="ECO:0000269|PubMed:8702543"; MUTAGEN 628; /note="R->C: Greatly reduced binding to IP4 and to phospholipids."; /evidence="ECO:0000269|PubMed:8702543
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8702543
uniprot
proteins
sequence_length
847
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}.
uniprot
proteins