DCTN3
entrez
11258
canonical
uniprot
O75935
canonical
ensembl
ENSG00000137100
resolver
ensp
ENSP00000259632
resolver
ensp
ENSP00000343986
resolver
ensp
ENSP00000368196
resolver
ensp
ENSP00000432915
resolver
ensp
ENSP00000656954
resolver
enst
ENST00000477738
resolver
genesymbol
DCTN3
resolver
genesymbol_syn
DCTN22
resolver
hgnc
HGNC:2713
resolver
uniprot
A6NII7
resolver
uniprot
B2RBM5
resolver
uniprot
Q5T1I5
resolver
uniprot
Q5T1I7
resolver
uniprot
Q5T8G3
resolver
uniprot
Q9BPU8
resolver
uniprot
X6RLR1
resolver
uniprot_entry
DCTN3_HUMAN
resolver
uniprot_entry
X6RLR1_HUMAN
resolver
uniprot_sec
A6NII7
resolver
uniprot_sec
B2RBM5
resolver
uniprot_sec
Q5T1I5
resolver
uniprot_sec
Q5T1I7
resolver
uniprot_sec
Q5T8G3
resolver
uniprot_sec
Q9BPU8
resolver
amino_acid_sequence
MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVPEHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQVKPAEE
uniprot
proteins
function
FUNCTION: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). Together with dynein may be involved in spindle assembly and cytokinesis (PubMed:9722614). {ECO:0000250|UniProtKB:F1SEC0, ECO:0000269|PubMed:9722614}.
uniprot
proteins
mass_dalton
21119
uniprot
proteins
protein_family
Dynactin subunit 3 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22814378
uniprot
proteins
pubmed
9722614
uniprot
proteins
sequence_length
186
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:9722614}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:9722614}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:9722614}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:9722614}. Cleavage furrow {ECO:0000269|PubMed:9722614}. Midbody {ECO:0000269|PubMed:9722614}. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
uniprot
proteins