MED6
entrez
10001
canonical
uniprot
O75586
canonical
ensembl
ENSG00000133997
resolver
ensp
ENSP00000256379
resolver
ensp
ENSP00000394502
resolver
ensp
ENSP00000413343
resolver
ensp
ENSP00000481920
resolver
enst
ENST00000615788
resolver
genesymbol
MED6
resolver
genesymbol_syn
ARC33
resolver
hgnc
HGNC:19970
resolver
uniprot
A0A087WYL7
resolver
uniprot
B4DU17
resolver
uniprot
B4E2P0
resolver
uniprot
O15401
resolver
uniprot
Q53FE3
resolver
uniprot
Q53HJ3
resolver
uniprot
Q6FHQ4
resolver
uniprot
Q9BTH1
resolver
uniprot
Q9UHL1
resolver
uniprot_entry
A0A087WYL7_HUMAN
resolver
uniprot_entry
MED6_HUMAN
resolver
uniprot_sec
B4DU17
resolver
uniprot_sec
B4E2P0
resolver
uniprot_sec
O15401
resolver
uniprot_sec
Q53FE3
resolver
uniprot_sec
Q53HJ3
resolver
uniprot_sec
Q6FHQ4
resolver
uniprot_sec
Q9BTH1
resolver
uniprot_sec
Q9UHL1
resolver
amino_acid_sequence
MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPEKRMRLQ
uniprot
proteins
function
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:16595664}.
uniprot
proteins
mass_dalton
28425
uniprot
proteins
protein_family
Mediator complex subunit 6 family
uniprot
proteins
pubmed
10024883
uniprot
proteins
pubmed
10235267
uniprot
proteins
pubmed
10508479
uniprot
proteins
pubmed
10993082
uniprot
proteins
pubmed
11867769
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15175163
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15989967
uniprot
proteins
pubmed
16574658
uniprot
proteins
pubmed
16595664
uniprot
proteins
pubmed
17000779
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
25944712
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
9734358
uniprot
proteins
sequence_length
246
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins