GSTM3
entrez
2947
canonical
uniprot
P21266
canonical
ensembl
ENSG00000134202
resolver
ensp
ENSP00000256594
resolver
ensp
ENSP00000354357
resolver
enst
ENST00000256594
resolver
enst
ENST00000361066
resolver
genesymbol
GSTM3
resolver
genesymbol_syn
GST5
resolver
hgnc
HGNC:4635
resolver
uniprot
O60550
resolver
uniprot
Q6FGJ9
resolver
uniprot
Q96HA3
resolver
uniprot_entry
GSTM3_HUMAN
resolver
uniprot_entry
Q6FGJ9_HUMAN
resolver
uniprot_sec
O60550
resolver
uniprot_sec
Q96HA3
resolver
amino_acid_sequence
MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
uniprot
proteins
ec_number
2.5.1.18
uniprot
proteins
function
FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers. {ECO:0000269|PubMed:10587441}.
uniprot
proteins
mass_dalton
26560
uniprot
proteins
mutagenesis
MUTAGEN 120; /note="Y->A: No effect."; /evidence="ECO:0000269|PubMed:10587441"; MUTAGEN 120; /note="Y->F: Strongly increased catalytic activity."; /evidence="ECO:0000269|PubMed:10587441"; MUTAGEN 213; /note="N->F: Strongly increased catalytic activity."; /evidence="ECO:0000269|PubMed:10587441"; MUTAGEN 213; /note="N->G: No effect."; /evidence="ECO:0000269|PubMed:10587441
uniprot
proteins
post_translational_modification
PTM: The N-terminus is blocked.
uniprot
proteins
protein_family
GST superfamily
uniprot
proteins
protein_family
Mu family
uniprot
proteins
pubmed
10587441
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
2345169
uniprot
proteins
pubmed
28112733
uniprot
proteins
pubmed
8218382
uniprot
proteins
pubmed
8373352
uniprot
proteins
pubmed
9882431
uniprot
proteins
sequence_length
225
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm.
uniprot
proteins