CYSLTR1
entrez
10800
canonical
uniprot
Q9Y271
canonical
ensembl
ENSG00000173198
resolver
ensp
ENSP00000362401
resolver
ensp
ENSP00000478492
resolver
ensp
ENSP00000526927
resolver
ensp
ENSP00000625285
resolver
ensp
ENSP00000625286
resolver
enst
ENST00000373304
resolver
enst
ENST00000614798
resolver
enst
ENST00000856868
resolver
enst
ENST00000955226
resolver
enst
ENST00000955227
resolver
genesymbol
CYSLTR1
resolver
genesymbol_syn
CYSLT1
resolver
hgnc
HGNC:17451
resolver
uniprot
B2R954
resolver
uniprot
D3DTE4
resolver
uniprot
Q38Q88
resolver
uniprot
Q38Q91
resolver
uniprot
Q5JS94
resolver
uniprot
Q8IV19
resolver
uniprot_entry
CLTR1_HUMAN
resolver
uniprot_entry
Q38Q88_HUMAN
resolver
uniprot_entry
Q38Q91_HUMAN
resolver
uniprot_sec
B2R954
resolver
uniprot_sec
D3DTE4
resolver
uniprot_sec
Q5JS94
resolver
uniprot_sec
Q8IV19
resolver
amino_acid_sequence
MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
uniprot
proteins
function
FUNCTION: Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
uniprot
proteins
mass_dalton
38541
uniprot
proteins
protein_family
G protein-coupled receptor 1 family
uniprot
proteins
pubmed
10391245
uniprot
proteins
pubmed
10462554
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15772651
uniprot
proteins
sequence_length
337
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
uniprot
proteins
transmembrane_region
TRANSMEM 29..49; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 58..78; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 107..127; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 142..162; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 194..214; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 231..251; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 277..297; /note="Helical; Name=7"; /evidence="ECO:0000255
uniprot
proteins