Cep162
entrez
300880
canonical
uniprot
Q4KLH6
canonical
ensembl
ENSRNOG00000010608
resolver
ensp
ENSRNOP00000014165
resolver
ensp
ENSRNOP00000075055
resolver
enst
ENSRNOT00000083934
resolver
genesymbol
Cep162
resolver
genesymbol_syn
Qn1
resolver
uniprot
A0A8L2R9X6
resolver
uniprot_entry
A0A8L2R9X6_RAT
resolver
uniprot_entry
CE162_RAT
resolver
amino_acid_sequence
MAHYSKVDLDEEFERFMKELSDDSFENSNETPSQPNKDRKKKDTAPWWIAEDGFEDDGLLGTNVSYLKTKKTYQPITDMEEENEKVQFLKSSGTSVLSVDSLEANELVASELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSAQFRVLHRYQGNVEPAEGGRENESEHKELPETYSDDFEDAEDTDEPLITKDEETRPKENPESGKGSFPNQEEEKTGMLANVVLLDSFDSVEDVDLNNHERPTPKAKALPEMAGGELAETGVSYGQSSGDTEALHQAYHHVAHSLGDTGEPRIEASPGHSVRSSAKDGLQENEESSKNISTTESDLPTVEELMKPIRIDSYGIRGFDLQPVSLQKAVGSKEAESVSSLPLTVNTNTMSQDTRHVSPFPHEQDESVVLHRTAGEGVGSSCPATEEHLDKMYLEILRKKTSVNPSLLPQDNKANQTSRSRLSAREEAPVTSKQVPCKKARSAPPLPRRKPQSGLYASARSSGYSKPSSPLQFFSALEKKTSKDNTKTKNVRPIPTSNQFRKREILSGTKLIKPAALNKPSPHREGSPATPKRPEDPSDDSFVQLQTETLGSYGGNREKELLMLKRAQDAEEKWRGAQALIEQIKMTFSEKEKELENTVESLKRQQERELFKLNQENYILQAKLSSFEETSRKQRWLQFGETSDPLTEEKLKQIQKEIQEQETLLQGYQQENERLYSQVKDLQEQNKKNEERMFKENQNLFSELASLKEQMHKNHFLPQAVENIEPTKNQSFTDLLAELRAAQKEKNHLMEDIKRLKQDKQALEVDLERVKRERDQAKDQIAYTTGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEETERLKLEIEKLKTESGSPANQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSVDRNTVDFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQMLAHRQREAPQNQHNSSSRLKALETELGGIKEAHQITVRKLEAEIDVLKHQNAHLEHKKNDKEDQDLQSIEFQVEQAQARAKLARLNEELAAKGREIQDLTKTVERLQKERRMMLSRQSPRGREEMAAKRLKKEILHPNSGNANAFSETLGAKLYHPHTFTDSHISEVLEENYRLRSELEGLTLEREKLKMESEAAVCQLESSMKRVKDDAAAHIASLKAAHEREIEKLLCQNAVENSSSRVAELNRKIATQEVLLKHFQGQVNELQGKQESLSLSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEESTAKEF
uniprot
proteins
function
FUNCTION: Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
161001
uniprot
proteins
protein_family
CEP162 family
uniprot
proteins
pubmed
15057822
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16302001
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
1403
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16302001}. Nucleus {ECO:0000250}. Note=Localizes to the distal end of centrioles throughout the cell cycle. During ciliogenesis, found at the cilia base. Localizes to spindle microtubules during mitosis (By similarity). {ECO:0000250}.
uniprot
proteins