Trmt1
entrez
212528
canonical
uniprot
Q3TX08
canonical
ensembl
ENSMUSG00000001909
resolver
ensp
ENSMUSP00000001974
resolver
ensp
ENSMUSP00000105389
resolver
ensp
ENSMUSP00000105390
resolver
ensp
ENSMUSP00000316517
resolver
ensp
ENSMUSP00000316551
resolver
enst
ENSMUST00000109768
resolver
genesymbol
Trmt1
resolver
genesymbol_syn
D8Ertd812e
resolver
uniprot
A0A0R4IZW7
resolver
uniprot
E9PWD4
resolver
uniprot
Q3TBY4
resolver
uniprot
Q8R2M8
resolver
uniprot_entry
E9PWD4_MOUSE
resolver
uniprot_entry
TRM1_MOUSE
resolver
uniprot_sec
A0A0R4IZW7
resolver
uniprot_sec
Q3TBY4
resolver
uniprot_sec
Q8R2M8
resolver
amino_acid_sequence
MSLARTILWLSRPLRPAHSLCRAQFMERKAQKPPSPPAMENGTRSWEERPPADPVATVTEGAAKIVFPSANEVFYNPVQEFNRDLTCAVITEFARIHLGAKGIQIKVPGEKDSEKIAVDLSDQEEETAGKNENLAPGDWPRTAAVGEICEEGLRVLEGLAASGLRSIRFALEVPGLQSVVANDASARAVELMHRNVELNGVAHLVQPNQADARMLMYQHQKAPERFDVIDLDPYGSPAPFLDAAVQAVSDGGLLCVTCTDMAVLAGNSGETCYSKYGAMALKSRACHEMALRIVLHSLDLHANCYQRYIVPLLSISADFYIRVFVRVFTGQAKVKSSASKQALVFQCVGCGAFYLQRLGKASGDPGGRIKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLDAVTTNPGRFHTSMRIQGVLSVVTEELPDVPLYYTLDQLSSTIHCNTPRLLQLRSALLHAGFRVSLSHACKNAVKTDAPPEALWDIMRCWEKECPVKRERLSESSPAFRILAVEPRLKANFNIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAASEDLAGRRRLLQNKRKEPAEDPAQRAARLKTFPCKRFKEGTCQLGDQCCYSHSPAAPVASGDIPIEECPETTTKISPGPKAAAGGIPGPGVD
uniprot
proteins
ec_number
2.1.1.216
uniprot
proteins
function
FUNCTION: Dimethylates a single guanine residue at position 26 of most nuclear- and mitochondrial-encoded tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (By similarity). tRNA guanine(26)-dimethylation is required for redox homeostasis and ensure proper cellular proliferation and oxidative stress survival (By similarity). {ECO:0000250|UniProtKB:Q9NXH9}.
uniprot
proteins
mass_dalton
72373
uniprot
proteins
protein_family
Class I-like SAM-binding methyltransferase superfamily
uniprot
proteins
protein_family
Trm1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
663
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion {ECO:0000250|UniProtKB:Q9NXH9}.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus {ECO:0000250|UniProtKB:Q9NXH9}. Cytoplasm {ECO:0000250|UniProtKB:Q9NXH9}.
uniprot
proteins