Afap1
entrez
140935
canonical
uniprot
Q8VH46
canonical
ensembl
ENSRNOG00000060665
resolver
ensp
ENSRNOP00000069497
resolver
ensp
ENSRNOP00000069806
resolver
ensp
ENSRNOP00000095531
resolver
enst
ENSRNOT00000089006
resolver
enst
ENSRNOT00000090597
resolver
enst
ENSRNOT00000117533
resolver
genesymbol
Afap1
resolver
genesymbol_syn
Afap
resolver
uniprot
A0A0G2JVI5
resolver
uniprot
A0A8I6ALM6
resolver
uniprot
G3V6Z3
resolver
uniprot_entry
A0A0G2JVI5_RAT
resolver
uniprot_entry
A0A8I6ALM6_RAT
resolver
uniprot_entry
AFAP1_RAT
resolver
uniprot_entry
G3V6Z3_RAT
resolver
amino_acid_sequence
MEELIVELRLFLELLDHEYLTSTVREKKAVLTNILLRMQSSKGFEVKDHAQKAETNNLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSEAMGSSYESYDEEEEDGKGKKTQHQCHHEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCSITYIPRDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDPECSPPPSASVPVNKAELEKKLSSERPSSDGEGVVENGVTTCNGKEQAKRKKPSKSEAKGTVSKVTGKKITKIIGLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDSKLILHKDRADLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPGALHYDYIDVEMSANVIQTAKQTFCFMNRRAVSTSPYLGSLSNGYAHPSGTALHYDDVPCVNGSLKNKKPPASSNGLPVKGRAPSSQQKKVESAGGVKRTASNAEQYKYGKNRVEADAKRLQSKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKTQVALEDKLKRLEEECKQREAERVSLELELTEVKESLKKALAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDAEGPLPVNSAAVLKKSQPSSSSSPCRGHVLQKAREWELKNGT
uniprot
proteins
function
FUNCTION: Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
80752
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues. {ECO:0000269|PubMed:12114187}.
uniprot
proteins
pubmed
12114187
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
731
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:12114187}.
uniprot
proteins