Cel
entrez
12613
canonical
uniprot
Q64285
canonical
ensembl
ENSMUSG00000026818
resolver
ensp
ENSMUSP00000028161
resolver
enst
ENSMUST00000028161
resolver
genesymbol
Cel
resolver
genesymbol_syn
Lip1
resolver
uniprot
Q3V2H7
resolver
uniprot_entry
CEL_MOUSE
resolver
uniprot_entry
Q3V2H7_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Activated by bile salts such as sodium taurocholate. {ECO:0000269|PubMed:27509211}.
uniprot
proteins
amino_acid_sequence
MGRLEVLFLGLTCCLAAACAAKLGAVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFATAKTLENPQRHPGWQGTLKATNFKKRCLQATITQDNTYGQEDCLYLNIWVPQGRKQVSHNLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGMALSPWAIQKNPLFWAKTIAKKVGCPTEDTGKMAACLKITDPRALTLAYKLPVKKQEYPVVHYLAFIPVIDGDFIPDDPINLYNNTADIDYIAGINNMDGHLFATIDVPAVDKTKQTVTEEDFYRLVSGHTVAKGLKGAQATFDIYTESWAQDPSQENMKKTVVAFETDVLFLIPTEIALAQHKAHAKSAKTYSYLFSHPSRMPIYPKWMGADHADDLQYVFGKPFATPLGYRPQDRAVSKAMIAYWTNFARSGDPNMGNSPVPTHWYPYTLENGNYLDITKTITSASMKEHLREKFLKFWAVTFEVLPTVTGDQDTLTPPEDDSEVAPDPPSDDSQVVPVPPTDDSVEAQMPATIGF
uniprot
proteins
ec_number
3.1.1.13
uniprot
proteins
ec_number
3.1.1.3
uniprot
proteins
ec_number
3.1.1.6
uniprot
proteins
function
FUNCTION: Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs) (PubMed:27509211). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (PubMed:27509211). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). {ECO:0000250|UniProtKB:P19835, ECO:0000269|PubMed:27509211}.
uniprot
proteins
mass_dalton
65813
uniprot
proteins
protein_family
Type-B carboxylesterase/lipase family
uniprot
proteins
pubmed
11834744
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
27509211
uniprot
proteins
pubmed
8522186
uniprot
proteins
pubmed
8530060
uniprot
proteins
sequence_length
599
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P19835}.
uniprot
proteins