FAM3B
entrez
54097
canonical
uniprot
P58499
canonical
ensembl
ENSG00000183844
resolver
ensp
ENSP00000350673
resolver
ensp
ENSP00000381641
resolver
ensp
ENSP00000381642
resolver
genesymbol
FAM3B
resolver
genesymbol_syn
C21orf11
resolver
genesymbol_syn
C21orf76
resolver
hgnc
HGNC:1253
resolver
uniprot_entry
FAM3B_HUMAN
resolver
amino_acid_sequence
MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
uniprot
proteins
function
FUNCTION: Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. {ECO:0000269|PubMed:16114871}.
uniprot
proteins
mass_dalton
25982
uniprot
proteins
post_translational_modification
PTM: 2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46.; PTM: O-glycosylated. {ECO:0000250}.
uniprot
proteins
protein_family
FAM3 family
uniprot
proteins
pubmed
11707072
uniprot
proteins
pubmed
12160727
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16114871
uniprot
proteins
sequence_length
235
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted. Note=Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure.
uniprot
proteins