Mycn
entrez
18109
canonical
uniprot
P03966
canonical
ensembl
ENSMUSG00000037169
resolver
ensp
ENSMUSP00000045993
resolver
ensp
ENSMUSP00000114225
resolver
enst
ENSMUST00000043396
resolver
enst
ENSMUST00000130990
resolver
genesymbol
Mycn
resolver
genesymbol_syn
Nmyc
resolver
genesymbol_syn
Nmyc1
resolver
uniprot
Q3UII1
resolver
uniprot
Q61978
resolver
uniprot_entry
MYCN_MOUSE
resolver
uniprot_entry
Q3UII1_MOUSE
resolver
uniprot_sec
Q61978
resolver
amino_acid_sequence
MPSCTASTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRAFPEHSPEPSNWATEMLLPEADLWGNPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVNEKLQHGHGPPGVSSACSAPGVGASSPGGRALGGSSSASHTGATLPTDLSHPAAECVDPAVVFPFPVNKRESASVPAAPTSAPATSAAVTSVSVPATAPVAAPARAGGRPASSGEAKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNNKAVTTFTITVRPKTSALGLGRAQPGELILKRCVPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVVPAKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHALQANEHQLLLEKEKLQARQQQLLKKIEHARTC
uniprot
proteins
function
FUNCTION: Positively regulates the transcription of MYCNOS in neuroblastoma cells. {ECO:0000250|UniProtKB:P04198}.
uniprot
proteins
mass_dalton
49572
uniprot
proteins
mutagenesis
MUTAGEN 58; /note="T->M: Results in decreased phosphorylation and subsequent protein accumulation. Heterozygous mutant mice have postaxial polydactyly, higher brain weight and thicker cerebral cortex layers than wild-type animals, and reproductive system and kidney anomalies."; /evidence="ECO:0000269|PubMed:37710961
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by GSK3-beta which may promote its degradation. Phosphorylated by AURKA. {ECO:0000250|UniProtKB:P04198}.
uniprot
proteins
pubmed
2555695
uniprot
proteins
pubmed
3015591
uniprot
proteins
pubmed
30573562
uniprot
proteins
pubmed
3287334
uniprot
proteins
pubmed
3513190
uniprot
proteins
pubmed
37710961
uniprot
proteins
pubmed
8521822
uniprot
proteins
pubmed
8617250
uniprot
proteins
sequence_length
462
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus.
uniprot
proteins