Tmem45b
entrez
315524
canonical
uniprot
Q497B2
canonical
ensembl
ENSRNOG00000008515
resolver
ensembl
ENSRNOG00055009166
resolver
ensembl
ENSRNOG00060012045
resolver
ensembl
ENSRNOG00065014997
resolver
ensp
ENSRNOP00000011329
resolver
ensp
ENSRNOP00055012420
resolver
ensp
ENSRNOP00060016080
resolver
ensp
ENSRNOP00065019398
resolver
enst
ENSRNOT00000011329
resolver
enst
ENSRNOT00055015505
resolver
enst
ENSRNOT00060020422
resolver
enst
ENSRNOT00065024816
resolver
genesymbol
Tmem45b
resolver
uniprot_entry
TM45B_RAT
resolver
amino_acid_sequence
MANFKGHALPGSFFLIFGLWWSVKYPLKYFHQKGLKKNRLSLQQQRIEIIEGAVKALFAVIGILAEQFVPDGPHLHLYHENQWTKLMNWQHSTMYLFFGVSGIIDMLTYLYFNIVPLGLDRVVLAMAVFVEGFLFYFHVHGRPPLDQHIHSLLLFSLFGATISICLEVILRDNIVLELFRTTLLILQGTWFWQIGFVLFPPFGTPEWDQKDMDNVMFITMCFCWHYLVALCITAINYSLVYCFLTRVRRRAEGEIIGIQKLKSDHTYQSTLLSGSDEE
uniprot
proteins
function
FUNCTION: Plays a role in innate immunity. Essential for inflammation- and tissue injury-induced mechanical pain hypersensitivity. {ECO:0000250|UniProtKB:Q8VCZ2, ECO:0000250|UniProtKB:Q96B21}.
uniprot
proteins
mass_dalton
32338
uniprot
proteins
protein_family
TMEM45 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
278
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endosome membrane {ECO:0000250|UniProtKB:Q96B21}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000250|UniProtKB:Q96B21}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q96B21}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 7..27; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 49..69; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 95..115; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 117..137; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 149..169; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 183..203; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 215..235; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins