Slc6a17
entrez
229706
canonical
uniprot
Q8BJI1
canonical
ensembl
ENSMUSG00000027894
resolver
ensp
ENSMUSP00000029499
resolver
ensp
ENSMUSP00000129379
resolver
ensp
ENSMUSP00000307227
resolver
enst
ENSMUST00000029499
resolver
enst
ENSMUST00000169449
resolver
genesymbol
Slc6a17
resolver
genesymbol_syn
Ntt4
resolver
uniprot
A0A0R4J087
resolver
uniprot
B2RUH5
resolver
uniprot
Q8C057
resolver
uniprot
Q8CGQ9
resolver
uniprot_entry
A0A0R4J087_MOUSE
resolver
uniprot_entry
S6A17_MOUSE
resolver
uniprot_sec
B2RUH5
resolver
uniprot_sec
Q8C057
resolver
uniprot_sec
Q8CGQ9
resolver
amino_acid_sequence
MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGETGGKQKVAEEELDTEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYSVIMTVKEKQFPALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFQPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLDNSNNPNGRYGSGYLLASTPESEL
uniprot
proteins
function
FUNCTION: Synaptic vesicle transporter with apparent selectivity for neutral amino acids. The transport is sodium-coupled but chloride-independent, likely driven by the proton electrochemical gradient generated by vacuolar H(+)-ATPase in an overall electrogenic mechanism. May contribute to the synaptic uptake of neurotransmitter precursors in a process coupled in part to vesicle exocytosis. {ECO:0000250|UniProtKB:P31662}.
uniprot
proteins
mass_dalton
81071
uniprot
proteins
protein_family
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17114649
uniprot
proteins
pubmed
18034455
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
25704603
uniprot
proteins
sequence_length
727
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:P31662}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P31662}. Postsynapse {ECO:0000269|PubMed:25704603}. Presynapse {ECO:0000269|PubMed:25704603}. Note=Localizes at synaptic junctions - at both pre- and post-synaptic sites - particularly in excitatory glutamatergic terminals. {ECO:0000269|PubMed:25704603}.
uniprot
proteins
transmembrane_region
TRANSMEM 69..89; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 97..116; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 141..161; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 225..243; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 252..269; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 305..322; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 334..355; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 452..471; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 495..513; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 529..549; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 570..591; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 619..641; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins