Rhoq
entrez
104215
canonical
uniprot
Q8R527
canonical
ensembl
ENSMUSG00000024143
resolver
ensp
ENSMUSP00000024956
resolver
enst
ENSMUST00000024956
resolver
genesymbol
Rhoq
resolver
genesymbol_syn
Arhq
resolver
genesymbol_syn
Tc10
resolver
uniprot
Q7TNC0
resolver
uniprot
Q80VH4
resolver
uniprot_entry
RHOQ_MOUSE
resolver
uniprot_sec
Q7TNC0
resolver
uniprot_sec
Q80VH4
resolver
activity_regulation
ACTIVITY REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP, GTPase activating proteins (GAPs) which increase the GTP hydrolysis activity, and GDP dissociation inhibitors which inhibit the dissociation of the nucleotide from the GTPase. {ECO:0000250}.
uniprot
proteins
amino_acid_sequence
MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPVCVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
uniprot
proteins
ec_number
3.6.5.2
uniprot
proteins
function
FUNCTION: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
22645
uniprot
proteins
post_translational_modification
PTM: May be post-translationally modified by both palmitoylation and polyisoprenylation. {ECO:0000250}.
uniprot
proteins
protein_family
Rho family
uniprot
proteins
protein_family
Small GTPase superfamily
uniprot
proteins
pubmed
10490598
uniprot
proteins
pubmed
12456725
uniprot
proteins
pubmed
12773384
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
205
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
uniprot
proteins