DUSP29
entrez
338599
canonical
uniprot
Q68J44
canonical
ensembl
ENSG00000188716
resolver
ensembl
ENSG00000281660
resolver
ensp
ENSP00000340609
resolver
ensp
ENSP00000487404
resolver
ensp
ENSP00000614348
resolver
enst
ENST00000338487
resolver
enst
ENST00000625469
resolver
enst
ENST00000944289
resolver
genesymbol
DUSP29
resolver
genesymbol_syn
DUPD1
resolver
genesymbol_syn
DUSP27
resolver
hgnc
HGNC:23481
resolver
uniprot
B2RP93
resolver
uniprot_entry
DUS29_HUMAN
resolver
uniprot_sec
B2RP93
resolver
amino_acid_sequence
MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL
uniprot
proteins
ec_number
3.1.3.16
uniprot
proteins
ec_number
3.1.3.48
uniprot
proteins
function
FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (PubMed:17498703). Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase (By similarity). Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity). {ECO:0000250|UniProtKB:Q8BK84, ECO:0000269|PubMed:17498703}.
uniprot
proteins
mass_dalton
25336
uniprot
proteins
protein_family
Non-receptor class dual specificity subfamily
uniprot
proteins
protein_family
Protein-tyrosine phosphatase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17498703
uniprot
proteins
pubmed
21543850
uniprot
proteins
sequence_length
220
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17498703}. Nucleus {ECO:0000250|UniProtKB:Q8BK84}.
uniprot
proteins