CYB561D2
entrez
11068
canonical
uniprot
O14569
canonical
ensembl
ENSG00000114395
resolver
ensp
ENSP00000232508
resolver
ensp
ENSP00000391209
resolver
ensp
ENSP00000400454
resolver
ensp
ENSP00000410663
resolver
ensp
ENSP00000573894
resolver
ensp
ENSP00000573895
resolver
ensp
ENSP00000573897
resolver
enst
ENST00000232508
resolver
enst
ENST00000418577
resolver
enst
ENST00000424512
resolver
enst
ENST00000425346
resolver
enst
ENST00000903835
resolver
enst
ENST00000903836
resolver
enst
ENST00000903838
resolver
genesymbol
CYB561D2
resolver
genesymbol_syn
101F6
resolver
hgnc
HGNC:30253
resolver
uniprot
A8K552
resolver
uniprot_entry
C56D2_HUMAN
resolver
uniprot_sec
A8K552
resolver
amino_acid_sequence
MALSAETESHIYRALRTASGAAAHLVALGFTIFVAVLARPGSSLFSWHPVLMSLAFSFLMTEALLVFSPESSLLHSLSRKGRARCHWVLQLLALLCALLGLGLVILHKEQLGKAHLVTRHGQAGLLAVLWAGLQCSGGVGLLYPKLLPRWPLAKLKLYHATSGLVGYLLGSASLLLGMCSLWFTASVTGAAWYLAVLCPVLTSLVIMNQVSNAYLYRKRIQP
uniprot
proteins
ec_number
7.2.1.3
uniprot
proteins
function
FUNCTION: Transmembrane reductase that may use ascorbate as an electron donor in the cytoplasm and transfer electrons across endoplasmic reticulum membranes to reduce monodehydro-L-ascorbate radical and iron cations Fe(3+) in the lumen of that compartment. {ECO:0000269|PubMed:23235316, ECO:0000269|PubMed:23641721}.
uniprot
proteins
mass_dalton
23974
uniprot
proteins
pubmed
11085536
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
19734123
uniprot
proteins
pubmed
19892738
uniprot
proteins
pubmed
23235316
uniprot
proteins
pubmed
23641721
uniprot
proteins
sequence_length
222
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9WUE3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9WUE3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q53TN4}.
uniprot
proteins
transmembrane_region
TRANSMEM 18..38; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 47..67; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 86..106; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 123..143; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 163..183; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 187..207; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins