Aspg
entrez
246266
canonical
uniprot
O88202
canonical
ensembl
ENSRNOG00000012843
resolver
ensp
ENSRNOP00000017454
resolver
genesymbol
Aspg
resolver
uniprot
Q4G088
resolver
uniprot_entry
LPP60_RAT
resolver
uniprot_sec
Q4G088
resolver
activity_regulation
ACTIVITY REGULATION: Inhibited by phosphatidic acid. {ECO:0000269|PubMed:8119970}.
uniprot
proteins
amino_acid_sequence
MARATGPEQRLLAIYTGGTIGMRSEGGVLVPGRGLAAVLRTLHMLHDEEYARAHSLPEDTLVLPPASSDQRIIYKVLECQPLFDSSDMTITEWVQIAQTIERHYTQYQGFVVIHGTDTMAFAASVLSFMLENLQKPVILTGAQVPIHELWSDGRENLLGALLMAGQYVIPEVCLFFQNQLFRGNRTTKVDARRFAAFCSPNLPPLATVGADVTINRELVRKASWKSHLVVHSNMEPDVGLLRLYPGIPASLVRTFLQPPLKGVVMETFGSGNGPTKPDLIQELRAAAERGLIIVNCTHCLQGAVTSDYAPGMAMAGAGIISGFDMTSEAALAKLSYVLGQPGLSLSDRKKLLAKDLRGEMTLPTTDDLLGDDMLGCRATWLLSMNGSQDADAMKDVLLPGLALAAAHAGDLDTLQAFVELGRDLNLKDYSGQTPLHVAARRGHASVVAMLLQKGVDVDACNEDGQSPLLLAVRGRHQSVIRLLRAAGAHLSPQELEDVGTELCRLASRADSEGLRAWWQAGADLGQPDYDGHCALQVAEAAGNADVVALLQSLEDRVSAQPQPH
uniprot
proteins
ec_number
3.1.1.47
uniprot
proteins
ec_number
3.1.1.5
uniprot
proteins
ec_number
3.5.1.1
uniprot
proteins
function
FUNCTION: Exhibits lysophospholipase, transacylase, PAF acetylhydrolase and asparaginase activities (PubMed:10320809, PubMed:8119970, PubMed:9575212). Can catalyze three types of transacylation reactions: (1) acyl transfer from 1-acyl-sn-glycero-3-phosphocholine (1-acyl-GPC) to the sn-1(3) positions of glycerol and 2-acylglycerol (sn-1 to -1(3) transfer), (2) acyl transfer from 1-acyl-GPC to the sn-2 positions of 1-acyl-GPC, 1-acyl-sn-glycero-3-phosphoethanolamine (1-acyl-GPE), and other lysophospholipids (sn-1 to -2 transfer) and (3) acyl transfer from 2-acyl-GPC to the sn-1 position of 2-acyl-GPC and 2-acyl-GPE (sn-2 to -1 transfer) (PubMed:10320809). Mediates the synthesis of 1-arachidonoyl species of phospholipids by transferring the arachidonoyl residue from 2-arachidonoyl lysophospholipid to the sn-1 position of 2-acyl lysophospholipid (PubMed:10320809). {ECO:0000269|PubMed:10320809, ECO:0000269|PubMed:8119970, ECO:0000269|PubMed:9575212}.
uniprot
proteins
mass_dalton
60795
uniprot
proteins
protein_family
Asparaginase 1 family
uniprot
proteins
pubmed
10320809
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8119970
uniprot
proteins
pubmed
9575212
uniprot
proteins
sequence_length
564
uniprot
proteins