BRF1
entrez
2972
canonical
uniprot
Q92994
canonical
ensembl
ENSG00000185024
resolver
ensp
ENSP00000329029
resolver
ensp
ENSP00000369269
resolver
ensp
ENSP00000376340
resolver
ensp
ENSP00000388877
resolver
ensp
ENSP00000389859
resolver
ensp
ENSP00000446707
resolver
ensp
ENSP00000448387
resolver
ensp
ENSP00000580297
resolver
ensp
ENSP00000627263
resolver
ensp
ENSP00000648948
resolver
genesymbol
BRF1
resolver
genesymbol
HEL-S-76p
resolver
genesymbol_syn
BRF
resolver
genesymbol_syn
GTF3B
resolver
genesymbol_syn
TAF3B2
resolver
genesymbol_syn
TAF3C
resolver
hgnc
HGNC:11551
resolver
uniprot
B3KU36
resolver
uniprot
B4DIG5
resolver
uniprot
B7Z2N3
resolver
uniprot
F5H5Z7
resolver
uniprot
F8WA46
resolver
uniprot
Q13223
resolver
uniprot
Q3SYD9
resolver
uniprot
Q5PR24
resolver
uniprot
Q6IQ02
resolver
uniprot
Q96KX3
resolver
uniprot
Q9HCW6
resolver
uniprot
Q9HCW7
resolver
uniprot
Q9HCW8
resolver
uniprot
V9HVY2
resolver
uniprot_entry
TF3B_HUMAN
resolver
uniprot_entry
V9HVY2_HUMAN
resolver
uniprot_sec
B3KU36
resolver
uniprot_sec
B4DIG5
resolver
uniprot_sec
B7Z2N3
resolver
uniprot_sec
F5H5Z7
resolver
uniprot_sec
F8WA46
resolver
uniprot_sec
Q13223
resolver
uniprot_sec
Q3SYD9
resolver
uniprot_sec
Q5PR24
resolver
uniprot_sec
Q6IQ02
resolver
uniprot_sec
Q96KX3
resolver
uniprot_sec
Q9HCW6
resolver
uniprot_sec
Q9HCW7
resolver
uniprot_sec
Q9HCW8
resolver
amino_acid_sequence
MTGRVCRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGDEDDGY
uniprot
proteins
disease_involvement
DISEASE: Cerebellofaciodental syndrome (CFDS) [MIM:616202]: An autosomal recessive disorder characterized by cerebellar hypoplasia, delayed development and intellectual disability, as well as facial dysmorphic features, short stature, microcephaly, and dental anomalies. {ECO:0000269|PubMed:25561519}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
uniprot
proteins
mass_dalton
73840
uniprot
proteins
protein_family
TFIIB family
uniprot
proteins
pubmed
10921893
uniprot
proteins
pubmed
12508121
uniprot
proteins
pubmed
14592981
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17081983
uniprot
proteins
pubmed
18377933
uniprot
proteins
pubmed
18669648
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25561519
uniprot
proteins
pubmed
7624363
uniprot
proteins
pubmed
8943358
uniprot
proteins
sequence_length
677
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
uniprot
proteins