A1EGX6
uniprot
A1EGX6
canonical
amino_acid_sequence
MEECEEPEEPISLGRQEYRRRRRPSQPMVDKSQQTEITEKRKAMASVQPPAPKATHSIGNIPGSKDNYSRKEYESLRLSSQLQKTLMKRKHVQDMTDKSLQTEPIVEEKVEVIFIDKTLKLEENTAGVGEIAPELPQSIPEVEIPTSRPTSHLIDRSQQTSCTGDWSLIYICPKEKVDKEQQTYFSELEIIIRSIPGSSMTKSKEETIPIAQEDPLVEINGSLEIEVLSPEELPDVMMSFTEGEISGELQALSNGEATVKGELFLTEEIPIQAPSPAEETSAAETATTTAKDVVDIQAPPADKLSSVEAPADISPTLVQGALSDKPSDQQYPQGTEMAPSELPVEDLDPFSEEVLEKVQALTTDSMLEDLGIAESTIAEETSGKVQHPLSEETSKEVPAEVHFPIAADFEESAILINEKFATDEVFEEYKPPIIEEVSADKATAEVQPPSAEDASEEVASSEVLPPSTEQGTVEDLTAEVLSTPTEEGPTEVPPQPTEEGPAEVPPPLSEEGPAEVPPAPAEEAPAEVLPPPAEEAPAEVPPPLTEEGPAEVPPPLTEEGPAEVPLAPAEEVPAEFLPPPAEEVPAEVPPPLTEEGPAEVPPPLTEEGPEEVPPLPAEEAPTKVPPSPAEKGSAEVSPPQTEEGPAEVPPPPAEEFPTEVPSSSAEEGSSEVPLPPTAERPEEAPPPATEEAPVEVLPPATEEAPVEVLPPATEEAPVEVQSPAAEEGLAEVPPPPTEESPTHDVPTEVQVPQAKESPGQVLPLSGESTAEEASAQVQPPSFEKAPLESLPLEEVEKIHLDNLPFEVQPLPTEDIAIGVPAESQALPADENPAREDTVETQPSSFEGAPIAENPIEAPLPASEADTGREDSAVHPSSLGPTDEAPAEIQILQTDDIPTEMSPVENQPLPAEEGFPEVVSEEEATAAEVRFPLSEGAPAQEATVEAQLTSVEESPKRASVDVQPLSPETPVEESPGVDLPLKTNEVTMQEFRVEKMPAEDSLPPSEQTPADQVLLKEHRLSQVADISEKELESTTLTSDKMSEGIDSVPEDVSGTKDDQISTFKIEGTIKIELKN
uniprot
proteins
function
FUNCTION: May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. {ECO:0000269|PubMed:17855365, ECO:0000269|PubMed:27398160}.
uniprot
proteins
mass_dalton
114979
uniprot
proteins
post_translational_modification
PTM: Phosphorylated by PKA upon spermatozoa capacitation conditions. {ECO:0000269|PubMed:17855365, ECO:0000269|PubMed:21871179, ECO:0000269|PubMed:27398160}.
uniprot
proteins
pubmed
17855365
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
21871179
uniprot
proteins
pubmed
27398160
uniprot
proteins
sequence_length
1074
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, cilium, flagellum {ECO:0000269|PubMed:17855365}. Note=Localizes to cortex of the fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella. {ECO:0000269|PubMed:17855365}.
uniprot
proteins