GRHPR
entrez
9380
canonical
uniprot
Q9UBQ7
canonical
ensembl
ENSG00000137106
resolver
ensp
ENSP00000313432
resolver
ensp
ENSP00000544703
resolver
ensp
ENSP00000643359
resolver
ensp
ENSP00000792845
resolver
genesymbol
GRHPR
resolver
genesymbol_syn
GLXR
resolver
hgnc
HGNC:4570
resolver
uniprot
A0A384N605
resolver
uniprot
Q5T945
resolver
uniprot
Q9H3E9
resolver
uniprot
Q9H636
resolver
uniprot
Q9UKX1
resolver
uniprot_entry
A0A384N605_HUMAN
resolver
uniprot_entry
GRHPR_HUMAN
resolver
uniprot_sec
Q5T945
resolver
uniprot_sec
Q9H3E9
resolver
uniprot_sec
Q9H636
resolver
uniprot_sec
Q9UKX1
resolver
amino_acid_sequence
MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL
uniprot
proteins
disease_involvement
DISEASE: Hyperoxaluria primary 2 (HP2) [MIM:260000]: A disorder characterized by elevated urinary excretion of oxalate and L-glycerate, progressive tissue accumulation of insoluble calcium oxalate, nephrolithiasis, nephrocalcinosis, and end-stage renal disease. {ECO:0000269|PubMed:10484776}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
ec_number
1.1.1.79
uniprot
proteins
ec_number
1.1.1.81
uniprot
proteins
function
FUNCTION: Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate, oxidizes D-glycerate to hydroxypyruvate. {ECO:0000269|PubMed:10484776, ECO:0000269|PubMed:10524214}.
uniprot
proteins
mass_dalton
35668
uniprot
proteins
protein_family
D-isomer specific 2-hydroxyacid dehydrogenase family
uniprot
proteins
pubmed
10484776
uniprot
proteins
pubmed
10524214
uniprot
proteins
pubmed
10679197
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16756993
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
328
uniprot
proteins