F9
entrez
14071
canonical
uniprot
P16294
canonical
ensembl
ENSMUSG00000031138
resolver
ensp
ENSMUSP00000033477
resolver
enst
ENSMUST00000033477
resolver
genesymbol
F9
resolver
genesymbol_syn
Cf9
resolver
uniprot
Q3UES1
resolver
uniprot_entry
FA9_MOUSE
resolver
uniprot_sec
Q3UES1
resolver
amino_acid_sequence
MKHLNTVMAESPALITIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVRGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDISSYECWCQVGFEGRNCELDATCNIKNGRCKQFCKNSPDNKVICSCTEGYQLAEDQKSCEPTVPFPCGRASISYSSKKITRAETVFSNMDYENSTEAVFIQDDITDGAILNNVTESSESLNDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEYNIDKKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANREYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTTFTIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
uniprot
proteins
ec_number
3.4.21.22
uniprot
proteins
function
FUNCTION: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. {ECO:0000250|UniProtKB:P00740}.
uniprot
proteins
mass_dalton
52978
uniprot
proteins
post_translational_modification
PTM: Activated by factor XIa, which excises the activation peptide. The propeptide can also be removed by snake venom protease (By similarity). Activated by coagulation factor VIIa-tissue factor (F7-F3) complex in calcium-dependent manner (By similarity). {ECO:0000250|UniProtKB:P00740}.; PTM: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. {ECO:0000250|UniProtKB:P00740}.; PTM: Predominantly O-glucosylated at Ser-99 by POGLUT1 in vitro. {ECO:0000250|UniProtKB:P00740}.; PTM: Carboxylated by vitamin K-dependent GGCX to form gamma-carboxyglutamate; these residues are essential for the binding of calcium. {ECO:0000250|UniProtKB:P00740}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
2303254
uniprot
proteins
pubmed
2323576
uniprot
proteins
sequence_length
471
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P00740}.
uniprot
proteins