ENO4
entrez
387712
canonical
uniprot
A6NNW6
canonical
ensembl
ENSG00000188316
resolver
ensp
ENSP00000345555
resolver
ensp
ENSP00000639755
resolver
genesymbol
ENO4
resolver
genesymbol_syn
C10orf134
resolver
hgnc
HGNC:31670
resolver
uniprot
A0A087WZY6
resolver
uniprot
A6NI74
resolver
uniprot
B8ZZN9
resolver
uniprot
J3KNX1
resolver
uniprot_entry
ENO4_HUMAN
resolver
uniprot_sec
A0A087WZY6
resolver
uniprot_sec
A6NI74
resolver
uniprot_sec
B8ZZN9
resolver
uniprot_sec
J3KNX1
resolver
amino_acid_sequence
MEEEGGGRSCGTTRELQKLKQQAMEYYRENDVPRRLEELLNSTFYLQPADVYGHLANCFSKLAKPPTICKIVGKDVLDGLGLPTLQVDIFCTIQNFPKNVCSVVISTHFEVHENALPELAKAEEAERASAVSTAVQWVNSTITHELQGMAPSDQAEVDHLLRIFFASKVQEDKGRKELEKSLEYSTVPTPLPPVPPPPPPPPPTKKKGQKPGRKDTITEKPIAPAEPVEPVLSGSMAIGAVSLAVAKACAMLLNKPLYLNIALLKHNQEQPTTLSMPLLMVSLVSCGKSSSGKLNLMKEVICIPHPELTTKQGVEMLMEMQKHINKIIEMPSPPKAETKKGHDGSKRGQQQITGKMSHLGCLTINCDSIEQPLLLIQEICANLGLELGTNLHLAINCAGHELMDYNKGKYEVIMGTYKNAAEMVDLYVDLINKYPSIIALIDPFRKEDSEQWDSIYHALGSRCYIIAGTASKSISKLLEQGNISIPKSNGLIIKHTNQTTMSDLVEITNLIDSKKHITVFGSTEGESSDDSLVDLAVGLGVRFIKLGGLSRGERVTKYNRLLTIEEELVQNGTLGFKEEHTFFYFNEEAEKAAEALEAAAAREPLVPTFPTQGVEESAETGASSG
uniprot
proteins
ec_number
4.2.1.11
uniprot
proteins
function
FUNCTION: Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis (By similarity). May be required for sperm motility and function. {ECO:0000250|UniProtKB:Q8C042}.
uniprot
proteins
mass_dalton
68465
uniprot
proteins
pathway_participation
PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5. {ECO:0000250|UniProtKB:Q8C042}.
uniprot
proteins
post_translational_modification
PTM: Synthesized as an approximately 70-kDa precursor, which then undergoes proteolytic cleavage to an approximately 60-kDa enzyme; HOATZ associates directly or indirectly with ENO4 to mediate this process before its transport to mature flagella. {ECO:0000250|UniProtKB:Q8C042}.
uniprot
proteins
protein_family
Enolase family
uniprot
proteins
pubmed
15164054
uniprot
proteins
pubmed
17974005
uniprot
proteins
sequence_length
625
uniprot
proteins