Kin
entrez
16588
canonical
uniprot
Q8K339
canonical
ensembl
ENSMUSG00000037262
resolver
ensp
ENSMUSP00000043614
resolver
ensp
ENSMUSP00000302454
resolver
enst
ENSMUST00000042512
resolver
genesymbol
Kin
resolver
genesymbol_syn
Btcd
resolver
genesymbol_syn
Kin17
resolver
uniprot
Q9CV58
resolver
uniprot_entry
KIN17_MOUSE
resolver
uniprot_sec
Q9CV58
resolver
amino_acid_sequence
MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFTELSRENEEEKVTFNLNKGAGGSAGATTSKSSSLGPSALKLLGSAASGKRKESSQSSAQPAKKKKSALDEIMELEEEKKRTARTDAWLQPGIVVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKAFSATIVIETGPLKGRRVEGIQYEDISKLA
uniprot
proteins
function
FUNCTION: Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo. Binds via its C-terminal domain to RNA in vitro. {ECO:0000250|UniProtKB:O60870, ECO:0000269|PubMed:15252136, ECO:0000269|PubMed:1923796, ECO:0000269|PubMed:8670903, ECO:0000269|PubMed:8954809}.
uniprot
proteins
mass_dalton
44722
uniprot
proteins
protein_family
KIN17 family
uniprot
proteins
pubmed
15252136
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
1715759
uniprot
proteins
pubmed
1923796
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
8670903
uniprot
proteins
pubmed
8954809
uniprot
proteins
sequence_length
391
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15252136}. Cytoplasm {ECO:0000269|PubMed:15252136}. Note=During S phase, strongly associated with the nuclear matrix, and to chromosomal DNA in the presence of DNA damage. Also shows cytoplasmic localization in elongated spermatids. {ECO:0000250|UniProtKB:O60870, ECO:0000269|PubMed:15252136}.
uniprot
proteins