MGARP
entrez
84709
canonical
uniprot
Q8TDB4
canonical
ensembl
ENSG00000137463
resolver
ensp
ENSP00000381928
resolver
enst
ENST00000398955
resolver
genesymbol
MGARP
resolver
genesymbol_syn
C4orf49
resolver
genesymbol_syn
CESP1
resolver
genesymbol_syn
HUMMR
resolver
genesymbol_syn
OSAP
resolver
hgnc
HGNC:29969
resolver
uniprot
Q9BZC3
resolver
uniprot_entry
HUMMR_HUMAN
resolver
uniprot_sec
Q9BZC3
resolver
amino_acid_sequence
MYLRRAVSKTLALPLRAPPNPAPLGKDASLRRMSSNRFPGSSGSNMIYYLVVGVTVSAGGYYAYKTVTSDQAKHTEHKTNLKEKTKAEIHPFQGEKENVAETEKASSEAPEELIVEAEVVDAEESPSATVVVIKEASACPGHVEAAPETTAVSAETGPEVTDAAARETTEVNPETTPEVTNAALDEAVTIDNDKDTTKNETSDEYAELEEENSPAESESSAGDDLQEEASVGSEAASAQG
uniprot
proteins
function
FUNCTION: Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity). Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons (By similarity). {ECO:0000250|UniProtKB:Q8VI64}.
uniprot
proteins
mass_dalton
25390
uniprot
proteins
pubmed
12036975
uniprot
proteins
pubmed
12770732
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16565373
uniprot
proteins
pubmed
19325000
uniprot
proteins
pubmed
19528298
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
21447634
uniprot
proteins
sequence_length
240
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16565373, ECO:0000269|PubMed:21447634}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8VI64}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q8VI64}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8VI64}. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q8VI64}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q8VI64}; Cytoplasmic side {ECO:0000250|UniProtKB:Q8VI64}. Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion. {ECO:0000250|UniProtKB:Q8VI64}.
uniprot
proteins
transmembrane_region
TRANSMEM 41..63; /note="Helical; Anchor for type IV membrane protein"; /evidence="ECO:0000255
uniprot
proteins