Myo5a
entrez
17918
canonical
uniprot
Q99104
canonical
ensembl
ENSMUSG00000034593
resolver
ensp
ENSMUSP00000116028
resolver
ensp
ENSMUSP00000117493
resolver
ensp
ENSMUSP00000120444
resolver
enst
ENSMUST00000123128
resolver
enst
ENSMUST00000136731
resolver
enst
ENSMUST00000155282
resolver
genesymbol
Myo5a
resolver
genesymbol_syn
Dilute
resolver
uniprot
D3YZ62
resolver
uniprot
D3Z4J3
resolver
uniprot
E9PUE5
resolver
uniprot_entry
D3YZ62_MOUSE
resolver
uniprot_entry
D3Z4J3_MOUSE
resolver
uniprot_entry
MYO5A_MOUSE
resolver
uniprot_sec
E9PUE5
resolver
amino_acid_sequence
MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLGDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPIEKKVPLDMSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKREDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIARV
uniprot
proteins
function
FUNCTION: Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein (By similarity). Involved in melanosome transport (PubMed:1996138). Also mediates the transport of vesicles to the plasma membrane (PubMed:22908308). May also be required for some polarization process involved in dendrite formation (By similarity). {ECO:0000250|UniProtKB:Q9QYF3, ECO:0000250|UniProtKB:Q9Y4I1, ECO:0000269|PubMed:1996138, ECO:0000269|PubMed:22908308}.
uniprot
proteins
mass_dalton
215538
uniprot
proteins
mutagenesis
MUTAGEN 1528; /note="R->H: Slightly reduces affinity for MLPH."; /evidence="ECO:0000269|PubMed:23798443"; MUTAGEN 1535; /note="I->E: Strongly reduces affinity for MLPH and SYTL4."; /evidence="ECO:0000269|PubMed:23798443"; MUTAGEN 1539; /note="K->E: Strongly reduces affinity for MLPH and SYTL4."; /evidence="ECO:0000269|PubMed:23798443
uniprot
proteins
protein_family
Myosin family
uniprot
proteins
protein_family
TRAFAC class myosin-kinesin ATPase superfamily
uniprot
proteins
pubmed
11887186
uniprot
proteins
pubmed
12147688
uniprot
proteins
pubmed
12221080
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
16452087
uniprot
proteins
pubmed
17151196
uniprot
proteins
pubmed
19144319
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
1996138
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
22908308
uniprot
proteins
pubmed
23798443
uniprot
proteins
sequence_length
1853
uniprot
proteins