Smyd1
entrez
12180
canonical
uniprot
P97443
canonical
ensembl
ENSMUSG00000055027
resolver
ensp
ENSMUSP00000073911
resolver
ensp
ENSMUSP00000109824
resolver
genesymbol
Smyd1
resolver
genesymbol_syn
Bop
resolver
uniprot
P97442
resolver
uniprot
P97444
resolver
uniprot
Q3UQT9
resolver
uniprot
Q6DFW7
resolver
uniprot_entry
Q3UQT9_MOUSE
resolver
uniprot_entry
SMYD1_MOUSE
resolver
uniprot_sec
P97442
resolver
uniprot_sec
P97444
resolver
uniprot_sec
Q6DFW7
resolver
amino_acid_sequence
MTIGSMENVEVFTSEGKGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECAAIKKYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLFLAAKEDPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIASEVLSYLQAYEEASHYARRMVDGYMKLYHHNNAQLGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRMQTEMELRMFRQNEFMYHKMREAALNNQPMQVMAEPSNEPAPALFHKKQ
uniprot
proteins
ec_number
2.1.1.354
uniprot
proteins
function
FUNCTION: Methylates histone H3 at 'Lys-4' (H3K4me). Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. {ECO:0000269|PubMed:11923873, ECO:0000269|PubMed:20943667}.
uniprot
proteins
mass_dalton
56496
uniprot
proteins
protein_family
Class V-like SAM-binding methyltransferase superfamily
uniprot
proteins
pubmed
11923873
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
20943667
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9013956
uniprot
proteins
sequence_length
490
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11923873}. Nucleus {ECO:0000269|PubMed:11923873}.
uniprot
proteins