P84109
uniprot
P84109
canonical
amino_acid_sequence
LNRDDDSDLHSPRYSFSEDTKCDDGWFVGTSRRTK
uniprot
proteins
function
FUNCTION: Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity). {ECO:0000250|UniProtKB:Q62417}.
uniprot
proteins
mass_dalton
4107
uniprot
proteins
post_translational_modification
PTM: O-glycosylated. {ECO:0000250}.
uniprot
proteins
pubmed
10085297
uniprot
proteins
pubmed
22673903
uniprot
proteins
sequence_length
35
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell junction, adherens junction {ECO:0000269|PubMed:10085297}. Cell membrane {ECO:0000269|PubMed:10085297}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10085297}. Cell junction, focal adhesion {ECO:0000250}. Nucleus {ECO:0000250}. Nucleus matrix {ECO:0000250}. Note=Colocalized with PXN at focal adhesions during myogenic differentiation. Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. {ECO:0000250}.
uniprot
proteins