TIMP4
entrez
7079
canonical
uniprot
Q99727
canonical
ensembl
ENSG00000157150
resolver
ensp
ENSP00000287814
resolver
enst
ENST00000287814
resolver
genesymbol
TIMP4
resolver
hgnc
HGNC:11823
resolver
uniprot
B2R7K6
resolver
uniprot_entry
TIMP4_HUMAN
resolver
uniprot_sec
B2R7K6
resolver
amino_acid_sequence
MPGSPRPAPSWVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPASADPADTEKMLRYEIKQIKMFKGFEKVKDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVFIHLCNYIEPWEDLSLVQRESLNHHYHLNCGCQITTCYTVPCTISAPNECLWTDWLLERKLYGYQAQHYVCMKHVDGTCSWYRGHLPLRKEFVDIVQP
uniprot
proteins
function
FUNCTION: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
uniprot
proteins
mass_dalton
25503
uniprot
proteins
protein_family
Protease inhibitor I35 (TIMP) family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8939999
uniprot
proteins
pubmed
9693046
uniprot
proteins
sequence_length
224
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted.
uniprot
proteins