Psmd4
entrez
19185
canonical
uniprot
O35226
canonical
ensembl
ENSMUSG00000005625
resolver
ensp
ENSMUSP00000071589
resolver
ensp
ENSMUSP00000102857
resolver
ensp
ENSMUSP00000170578
resolver
ensp
ENSMUSP00000334801
resolver
ensp
ENSMUSP00000357671
resolver
genesymbol
Psmd4
resolver
genesymbol_syn
Mcb1
resolver
uniprot
Q3ULG4
resolver
uniprot
Q91V59
resolver
uniprot
Q9JJM0
resolver
uniprot
Q9JJM1
resolver
uniprot
Q9JJM2
resolver
uniprot
Q9JJM3
resolver
uniprot_entry
PSMD4_MOUSE
resolver
uniprot_entry
Q3ULG4_MOUSE
resolver
uniprot_sec
Q91V59
resolver
uniprot_sec
Q9JJM0
resolver
uniprot_sec
Q9JJM1
resolver
uniprot_sec
Q9JJM2
resolver
uniprot_sec
Q9JJM3
resolver
amino_acid_sequence
MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATPGTEDSDDALLKMTINQQEFGRPGLPDLSSMTEEEQIAYAMQMSLQGTEFSQESADMDASSAMDTSDPVKEEDDYDVMQDPEFLQSVLENLPGVDPNNAAIRSVMGALASQATKDGKNDKKEEEKK
uniprot
proteins
function
FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains. {ECO:0000250|UniProtKB:P55036}.
uniprot
proteins
mass_dalton
40704
uniprot
proteins
protein_family
Proteasome subunit S5A family
uniprot
proteins
pubmed
10921894
uniprot
proteins
pubmed
15345747
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16857966
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
9511739
uniprot
proteins
sequence_length
376
uniprot
proteins