Proc
entrez
25268
canonical
uniprot
P31394
canonical
ensembl
ENSRNOG00000014376
resolver
ensp
ENSRNOP00000019596
resolver
ensp
ENSRNOP00000100621
resolver
enst
ENSRNOT00000019596
resolver
genesymbol
Proc
resolver
uniprot
F7FMY6
resolver
uniprot
Q68FY8
resolver
uniprot_entry
F7FMY6_RAT
resolver
uniprot_entry
PROC_RAT
resolver
uniprot_entry
Q68FY8_RAT
resolver
amino_acid_sequence
MWQFRIFLLFASTWGISGVSAHPDPVFSSSEGAHQVLRVRRANSFLEEVRAGSLERECMEEICDFEEAQEIFQNVEDTLAFWIKYFDGDQCSTPPLDHQCDSPCCGHGTCIDGLGGFSCSCDKGWEGRFCQQEMGFQDCRVKNGGCYHYCLEETRGRRCRCAPGYELADDHMHCRPTVNFPCGKLWKRTDKKRKNFKRDIDPEDEELELGPRIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCLESSKKLTVRLGEYDLRRRDPWELDLDIKEVLVHPNYTRSNSDNDIALLRLSQPATLSKTIVPICLPNSGLAQELSQAGQETVVTGWGYQSDKVKDGRRNRTFILTFIRIPLAARNDCMQVMNNVVSENMLCAGIIGDTRDACDGDSGGPMVVFFRGTWFLVGLVSWGEGCGHLNNYGVYTKVGSYLKWIHSYIGERDVSLKSPKL
uniprot
proteins
ec_number
3.4.21.69
uniprot
proteins
function
FUNCTION: Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (By similarity). Exerts a protective effect on the endothelial cell barrier function (By similarity). {ECO:0000250|UniProtKB:P04070}.
uniprot
proteins
mass_dalton
51912
uniprot
proteins
post_translational_modification
PTM: Carboxylated by vitamin K-dependent GGCX to form gamma-carboxyglutamate; these residues are essential for the binding of calcium. {ECO:0000250|UniProtKB:P04070}.; PTM: N- and O-glycosylated (By similarity). {ECO:0000250|UniProtKB:P04070}.; PTM: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. {ECO:0000250|UniProtKB:P04070}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
1627650
uniprot
proteins
sequence_length
461
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P04070}. Golgi apparatus {ECO:0000250|UniProtKB:P04070}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P04070}.
uniprot
proteins