Q761V0
uniprot
Q761V0
canonical
amino_acid_sequence
MDCSAPKEMNKQPANILEAAVPGHRDSPRAPRTSPEQDLPAEAPAATVQPPRVPRSASTGAQTFQSADARACEAQQSGVGFCNLSSPRAQATSAALRDLSEGHSAQANPPSGPAGAGNALHCKIPALRGPEEDANVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC
uniprot
proteins
function
FUNCTION: Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses (By similarity). {ECO:0000250|UniProtKB:P58295}.
uniprot
proteins
mass_dalton
87861
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000250|UniProtKB:Q9Y345}.
uniprot
proteins
protein_family
SLC6A5 subfamily
uniprot
proteins
protein_family
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family
uniprot
proteins
pubmed
15081419
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
799
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9Y345}; Multi-pass membrane protein {ECO:0000255}.
uniprot
proteins
transmembrane_region
TRANSMEM 202..222; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 229..249; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 273..293; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 397..417; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 433..453; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 472..492; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 510..530; /note="Helical; Name=7"; /evidence="ECO:0000255"; TRANSMEM 565..585; /note="Helical; Name=8"; /evidence="ECO:0000255"; TRANSMEM 611..631; /note="Helical; Name=9"; /evidence="ECO:0000255"; TRANSMEM 640..660; /note="Helical; Name=10"; /evidence="ECO:0000255"; TRANSMEM 677..697; /note="Helical; Name=11"; /evidence="ECO:0000255"; TRANSMEM 717..737; /note="Helical; Name=12"; /evidence="ECO:0000255
uniprot
proteins