Ndst3
entrez
83398
canonical
uniprot
Q9EQH7
canonical
ensembl
ENSMUSG00000027977
resolver
ensp
ENSMUSP00000029602
resolver
ensp
ENSMUSP00000118207
resolver
ensp
ENSMUSP00000120623
resolver
ensp
ENSMUSP00000122617
resolver
ensp
ENSMUSP00000133657
resolver
enst
ENSMUST00000029602
resolver
enst
ENSMUST00000124803
resolver
enst
ENSMUST00000132112
resolver
enst
ENSMUST00000154668
resolver
enst
ENSMUST00000172537
resolver
genesymbol
Ndst3
resolver
genesymbol_syn
Hsst3
resolver
uniprot
D3YXE5
resolver
uniprot
E9PZJ4
resolver
uniprot
G3UXE3
resolver
uniprot
Q6AXE0
resolver
uniprot
Q9D557
resolver
uniprot_entry
D3YXE5_MOUSE
resolver
uniprot_entry
E9PZJ4_MOUSE
resolver
uniprot_entry
NDST3_MOUSE
resolver
uniprot_sec
G3UXE3
resolver
uniprot_sec
Q6AXE0
resolver
uniprot_sec
Q9D557
resolver
amino_acid_sequence
MSFIMKPHRHFQRTLILLATFCMVSIIISAYYLYSGYKQESEVSGRASEVDCGDLQHIPSRLMEVRRTMISDASRTDPTVLVFVESQYSSLGQDIIMMLESIRFHYHTEIAPGKGDLPALTDNVKGKYVLIIYENILKYINMDSWNRSLLDKYCIEYGVGIIGFHKTSEKNLQSFQFRGFPFSISGNLAVKDCCINPHSPLLRVTKSSKLDRGSLPGTDWTVFQINHSTYQPVIFAKVKTPENLSPPISKHAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRTQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLIEQMILNKKFALEHGIPTDMGYAVSPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPRELDKSIHGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANFVQTWTNLRLQTLPPAQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALCLFLIMHPSILSNSPSPKSFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEDAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPNAPWELRTLQKRCLVPGWYANHIERWLVYFPPFQLLIIDGQHLRTTPATVMDEVQKFLGVSPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRAFLSSYYRDHNVELSKLLHRLGQPLPSWLRQELQKVR
uniprot
proteins
ec_number
2.8.2.-
uniprot
proteins
ec_number
2.8.2.8
uniprot
proteins
ec_number
3.-.-.-
uniprot
proteins
function
FUNCTION: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity. {ECO:0000269|PubMed:11087757}.
uniprot
proteins
mass_dalton
101040
uniprot
proteins
pathway_participation
PATHWAY: Glycan metabolism; heparan sulfate biosynthesis.; PATHWAY: Glycan metabolism; heparin biosynthesis.
uniprot
proteins
protein_family
NDST subfamily
uniprot
proteins
protein_family
Sulfotransferase 1 family
uniprot
proteins
pubmed
11087757
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16056228
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
873
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 14..34; /note="Helical; Signal-anchor for type II membrane protein"; /evidence="ECO:0000255
uniprot
proteins