Cdhr5
entrez
72040
canonical
uniprot
Q8VHF2
canonical
ensembl
ENSMUSG00000025497
resolver
ensp
ENSMUSP00000079484
resolver
ensp
ENSMUSP00000127292
resolver
enst
ENSMUST00000167263
resolver
genesymbol
Cdhr5
resolver
genesymbol_syn
Mucdhl
resolver
genesymbol_syn
Mupcdh
resolver
uniprot
A0PJK7
resolver
uniprot
F6UF26
resolver
uniprot
Q8CEJ3
resolver
uniprot
Q9D8I9
resolver
uniprot_entry
A0PJK7_MOUSE
resolver
uniprot_entry
CDHR5_MOUSE
resolver
uniprot_entry
F6UF26_MOUSE
resolver
uniprot_sec
Q8CEJ3
resolver
uniprot_sec
Q9D8I9
resolver
amino_acid_sequence
MGAPALLWPSLLLPWLTVLFGQPPGTLAQTQVCSVNQTIFRVEENTTVSEPLVNIFVPDGLHVTLGPLSTPYAFRIEGKDLFLNVTPDYEENSLLQADVECKRGDAVVVRLEVFVAVLDINDNAPKFSFEIKTFNVSEDTKVNTTVIPETQLKATDADINDILVYTLQEVTPNASKFFSLEGVNYPALKLDQTLDYFKNQNMTFMLLARDTWEENVEPSHTATATLVLNTLPADLRTPWFLPCSFTDGYVCIHAQYSAVVPTGHKLPSPLIMSPGPIYAVDGDQAINQSIIYSIIAGNTDGTFIINAHDGNLTMTKSIPSPMKFTLLIRADQEDMAQYSVTQAIVEARSVTGNPLQFSQSLYYGTVVLGSEAGTAVKDKTFPSEILRIQAQYPGFPDLNSAVTYRVTNSSEFMMNKDIMLTAVPMEEARTIRVEVEASNTVTKDTATAVVEIQVSERERTPTPPEAGGTTGPSSNTTMEAPLTSGTSQRPATTSSGGSVGPFPPGGTTLRPPTPASSIPGGSPTLGTSTSPQTTTPGGDSAQTPKPGTSHPTAPTSRTSTSLMTTSSRSDSTQTPKPGTSQPMVPIPGASTSSQPATPSGSSPQTPKPGTSQSTATGPISLPSTGAGEQGDGQRFSTVDMAVLGGVLGALLLLALICLVILVHKHYRHRLACCSGKASEPQPSGYDNLTFLPDHKAKWSPTPNRKPEPSPKLAQPPLRPPSPMSSSPTPPSSTPPSPQPKASGSPKTVQAGDSPSAVRSILTKERRPEGEGGYKAVWFGKDIGAEADVVVLNEPTADVDSASASGSEGSDDDDPDQKKTLRFGVDADNTYI
uniprot
proteins
function
FUNCTION: Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. {ECO:0000250|UniProtKB:Q9HBB8}.
uniprot
proteins
mass_dalton
88208
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250|UniProtKB:Q9JIK1}.
uniprot
proteins
pubmed
10801787
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
17242355
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
831
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Apical cell membrane {ECO:0000250|UniProtKB:Q9HBB8}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9HBB8}. Cell projection, microvillus membrane {ECO:0000250|UniProtKB:Q9HBB8}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9HBB8}.
uniprot
proteins
transmembrane_region
TRANSMEM 642..662; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins