AGMO
entrez
392636
canonical
uniprot
Q6ZNB7
canonical
ensembl
ENSG00000187546
resolver
ensp
ENSP00000341662
resolver
ensp
ENSP00000644213
resolver
ensp
ENSP00000644215
resolver
ensp
ENSP00000776859
resolver
enst
ENST00000342526
resolver
genesymbol
AGMO
resolver
genesymbol_syn
TMEM195
resolver
hgnc
HGNC:33784
resolver
uniprot
A4D114
resolver
uniprot
A6NCH5
resolver
uniprot
X5D773
resolver
uniprot_entry
ALKMO_HUMAN
resolver
uniprot_entry
X5D773_HUMAN
resolver
uniprot_sec
A4D114
resolver
uniprot_sec
A6NCH5
resolver
amino_acid_sequence
MKNPEAQQDVSVSQGFRMLFYTMKPSETSFQTLEEVPDYVKKATPFFISLMLLELVVSWILKGKPPGRLDDALTSISAGVLSRLPSLFFRSIELTSYIYIWENYRLFNLPWDSPWTWYSAFLGVDFGYYWFHRMAHEVNIMWAGHQTHHSSEDYNLSTALRQSVLQIYTSWIFYSPLALFIPPSVYAVHLQFNLLYQFWIHTEVINNLGPLELILNTPSHHRVHHGRNRYCIDKNYAGVLIIWDKIFGTFEAENEKVVYGLTHPINTFEPIKVQFHHLFSIWTTFWATPGFFNKFSVIFKGPGWGPGKPRLGLSEEIPEVTGKEVPFSSSSSQLLKIYTVVQFALMLAFYEETFADTAALSQVTLLLRVCFIILTLTSIGFLLDQRPKAAIMETLRCLMFLMLYRFGHLKPLVPSLSSAFEIVFSICIAFWGVRSMKQLTSHPWK
uniprot
proteins
ec_number
1.14.16.5
uniprot
proteins
function
FUNCTION: Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes. {ECO:0000269|PubMed:20643956}.
uniprot
proteins
mass_dalton
51500
uniprot
proteins
mutagenesis
MUTAGEN 132; /note="H->A: Loss of function; when associated with A-136; A-145; A-148; A-149; A-221; A-224 and A-225."; /evidence="ECO:0000269|PubMed:20643956"; MUTAGEN 136; /note="H->A: Loss of function; when associated with A-132; A-145; A-148; A-149; A-221; A-224 and A-225."; /evidence="ECO:0000269|PubMed:20643956"; MUTAGEN 145; /note="H->A: Loss of function; when associated with A-132; A-136; A-148; A-149; A-221; A-224 and A-225."; /evidence="ECO:0000269|PubMed:20643956"; MUTAGEN 148; /note="H->A: Loss of function; when associated with A-132; A-136; A-145; A-149; A-221; A-224 and A-225."; /evidence="ECO:0000269|PubMed:20643956"; MUTAGEN 149; /note="H->A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-221; A-224 and A-225."; /evidence="ECO:0000269|PubMed:20643956"; MUTAGEN 221; /note="H->A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-149; A-224 and A-225."; /evidence="ECO:0000269|PubMed:20643956"; MUTAGEN 224; /note="H->A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-149; A-221 and A-225."; /evidence="ECO:0000269|PubMed:20643956"; MUTAGEN 225; /note="H->A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-149; A-221 and A-224."; /evidence="ECO:0000269|PubMed:20643956
uniprot
proteins
protein_family
Sterol desaturase family
uniprot
proteins
protein_family
TMEM195 subfamily
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20643956
uniprot
proteins
pubmed
24275569
uniprot
proteins
sequence_length
445
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20643956}; Multi-pass membrane protein {ECO:0000269|PubMed:20643956}.
uniprot
proteins
transmembrane_region
TRANSMEM 43..63; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 111..131; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 334..354; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 363..383; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 413..433; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins