Hgh1
entrez
315094
canonical
uniprot
Q6AY79
canonical
ensembl
ENSRNOG00000029238
resolver
ensembl
ENSRNOG00065009929
resolver
ensp
ENSRNOP00000047549
resolver
ensp
ENSRNOP00065012045
resolver
enst
ENSRNOT00000040981
resolver
enst
ENSRNOT00065015944
resolver
genesymbol
Hgh1
resolver
genesymbol_syn
Brp16
resolver
genesymbol_syn
Fam203a
resolver
uniprot_entry
HGH1_RAT
resolver
amino_acid_sequence
MRGPGVGSGLSGERGLSGKEAGADTEVAELLPFLVPGARADLQAAAAQHVLALTGVGSGRTLLAGQTALLRALIDLAVAPIPAPSRDASRALVNLAADPDLHWQMLAADPELPVRLLRCVLDPQWPWAEELAAVLANLSREPAPCAVLTEKLVAAEPERLGLERLVSALCMPSYNASAPLHYLGPLLSNLSQQAEVRAFLLDPDRCVVQRLLPLTQYTDSSVRRGGVVGTLRNCCFEHRHHKWLLGPQVDILPFLLLPLAGPEEFSEEEMEELPVDLQYLSPDKQREPDADIRKMLIEAIMLLTATAPGRKQVRDQGAYLILRELYAWESEPDVRMACEKLIQVLIGDEPEVGMENLLEVQVPEDVERQLQELDQQEQQELAQERRDKGAPRT
uniprot
proteins
function
FUNCTION: Co-chaperone involved in the folding of nascent eukaryotic elongation factor eEF2, an essential component of the translation machinery. Recognizes a non-native conformation in the central domain of eEF2 and recruits the chaperonin-containing T-complex (TRiC) to the C-terminal region of the nascent polypeptide, preventing unproductive interactions and promoting efficient folding of the N-terminal GTPase domain. May also assist in eEF2 maturation by recruiting the molecular chaperone Hsp90. {ECO:0000250|UniProtKB:P48362}.
uniprot
proteins
mass_dalton
43132
uniprot
proteins
protein_family
HGH1 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
393
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P48362}.
uniprot
proteins