Iqub
entrez
296936
canonical
uniprot
Q45GW3
canonical
ensembl
ENSRNOG00000021729
resolver
ensembl
ENSRNOG00055022331
resolver
ensembl
ENSRNOG00060019314
resolver
ensp
ENSRNOP00000063053
resolver
ensp
ENSRNOP00055031247
resolver
ensp
ENSRNOP00060027438
resolver
enst
ENSRNOT00000064983
resolver
enst
ENSRNOT00055038387
resolver
enst
ENSRNOT00060033524
resolver
genesymbol
Iqub
resolver
uniprot
Q4FZV4
resolver
uniprot_entry
IQUB_RAT
resolver
uniprot_sec
Q4FZV4
resolver
amino_acid_sequence
MSDTEENVLDSPASGEAAGEVISIPGPTDEAEESDISPEQEYEIEGFTTESEETVEHYSDLSVSTPKSYDSKPRDEVVSLGSATDSHEQEYRLGDLGGDQRSEEDEMSFLYKIKAIKENLQSSVKECIATVKIVLIPAGQEIVMPFRVDAPFRFLKEHFAHLLRIPHHVLQMAYTGISVGNNESLIQYGVKPREIVQMNVFSSEPDQYPVRRIEGLSEGSKIITVTIQTGIERYEEVAVEIVKSDFHKPFLGGFRHKITGLEYHNAGTQTVPKKIPEKDNLFCRDTQTVFQKKKLQQTMNTTSTQMTKIGVYVSNMTDKLLTPGSYFSAAEYHARRLNAVIVIQTAYRRWHAKCYVDSLRLQKKMRLEWEKEEELKKIREKEEWIRMDYYRRHNPKTTEDFELLFNALELWRQEEVTQVEQYSSEAERKAALCELLEKETQIIASIGRHRYVAQLERQDVATQAFLDKCSASNTWRRPDGQTVEMDTQFTIRARELQSIYKCILLKNLSQDERLDILLTLKHTVKEHECKLTQEILELIDREVDLMMRGVKSHNLEGLRKRITTLFIHYIKTPLFNPEVAKHLKVPQDPLKFYDKIYFCHSCQMYLPSVEFSVSPTSHRVYRCRHCINLENETQRRESFLKYKCLLQRLYFSEANYEDNSHIAYLMQLQDIKYLTENIWASQSALSAWDDLNDLVMVRWNKHVEWSPWNCILLTKDEGTAHLKLESIEKGYGRLFIHKIKHKHILAKNYFSQVPVLASLILKDDEIEAIRSKYSTENPPKIIVPHGIVPN
uniprot
proteins
function
FUNCTION: Adapter protein that anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes. The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum. May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1. Additionally, may play a role in the functioning of cilia. Not required for the functioning of tracheal or ependymal cilia. {ECO:0000250|UniProtKB:Q8CDK3}.
uniprot
proteins
mass_dalton
91823
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
790
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q8CDK3}. Cell projection, cilium {ECO:0000250|UniProtKB:Q8CDK3}. Note=Localizes to the axoneme of sperm cells and the cilia of tracheal epithelial cells. {ECO:0000250|UniProtKB:Q8CDK3}.
uniprot
proteins