BHLHA15
entrez
168620
canonical
uniprot
Q7RTS1
canonical
ensembl
ENSG00000180535
resolver
ensp
ENSP00000326391
resolver
ensp
ENSP00000476312
resolver
ensp
ENSP00000600596
resolver
enst
ENST00000314018
resolver
enst
ENST00000609256
resolver
enst
ENST00000930537
resolver
genesymbol
BHLHA15
resolver
genesymbol_syn
BHLHB8
resolver
genesymbol_syn
MIST1
resolver
hgnc
HGNC:22265
resolver
uniprot
A4D271
resolver
uniprot
Q14DE4
resolver
uniprot_entry
BHA15_HUMAN
resolver
uniprot_sec
A4D271
resolver
uniprot_sec
Q14DE4
resolver
amino_acid_sequence
MKTKNRPPRRRAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRPGPSGPGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEGPGPKLYQHYQQQQQVAGGALGATEAQPQGHLQRYSTQIHSFREGT
uniprot
proteins
function
FUNCTION: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity). {ECO:0000250|UniProtKB:Q9QYC3}.
uniprot
proteins
mass_dalton
20818
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14516699
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
21269460
uniprot
proteins
sequence_length
189
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
uniprot
proteins