CEACAM20
entrez
125931
canonical
uniprot
Q6UY09
canonical
ensembl
ENSG00000273777
resolver
ensp
ENSP00000481812
resolver
ensp
ENSP00000481937
resolver
ensp
ENSP00000482943
resolver
ensp
ENSP00000483912
resolver
genesymbol
CEACAM20
resolver
hgnc
HGNC:24879
resolver
uniprot
A0A087WXE1
resolver
uniprot
A0A087WYH6
resolver
uniprot
A0A087WYM6
resolver
uniprot
A0A087WZX4
resolver
uniprot
A0A087X155
resolver
uniprot
A7LFK7
resolver
uniprot
A7LFK8
resolver
uniprot
A7LFK9
resolver
uniprot
A7LFL0
resolver
uniprot_entry
CEA20_HUMAN
resolver
uniprot_sec
A0A087WXE1
resolver
uniprot_sec
A0A087WYH6
resolver
uniprot_sec
A0A087WYM6
resolver
uniprot_sec
A0A087WZX4
resolver
uniprot_sec
A0A087X155
resolver
uniprot_sec
A7LFK7
resolver
uniprot_sec
A7LFK8
resolver
uniprot_sec
A7LFK9
resolver
uniprot_sec
A7LFL0
resolver
amino_acid_sequence
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSIVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLCIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYRNISQLQGRIRVELMQPPDLPEETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV
uniprot
proteins
function
FUNCTION: Together with the tyrosine-protein kinase SYK, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response. {ECO:0000250|UniProtKB:Q9D2Z1}.
uniprot
proteins
mass_dalton
65808
uniprot
proteins
post_translational_modification
PTM: Phosphorylated on tyrosine residues by SYK, SRC and FYN in vitro. {ECO:0000250|UniProtKB:Q9D2Z1}.
uniprot
proteins
protein_family
CEA family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
15057824
uniprot
proteins
sequence_length
596
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cell projection, microvillus membrane {ECO:0000250|UniProtKB:Q9D2Z1}; Single-pass type I membrane protein {ECO:0000305}. Apical cell membrane {ECO:0000250|UniProtKB:Q9D2Z1}; Single-pass type I membrane protein {ECO:0000305}. Note=Colocalizes with PTPRH and CEACAM1 at the apical brush border of intestinal cells.
uniprot
proteins
transmembrane_region
TRANSMEM 451..471; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins