Lage3
entrez
66192
canonical
uniprot
Q9CR70
canonical
ensembl
ENSMUSG00000015289
resolver
ensp
ENSMUSP00000015433
resolver
enst
ENSMUST00000015433
resolver
genesymbol
Lage3
resolver
genesymbol_syn
Itba2
resolver
uniprot_entry
LAGE3_MOUSE
resolver
amino_acid_sequence
MQTAHTGLSHTADGADGQTSRCCPGNAGTKAVIPSGAHPVARALEASRNSSKSMVPLTQRPGTRHHRFSLFVPFPTSLEAEIACGSLVPDVEPHRGLVGKELKVSGCMLEVRWIAEDSRLLRLSIINFLDQLSLVVNTIQLFGPPVSC
uniprot
proteins
function
FUNCTION: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex. {ECO:0000250|UniProtKB:Q14657}.
uniprot
proteins
mass_dalton
15824
uniprot
proteins
protein_family
CTAG/PCC1 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
28805828
uniprot
proteins
sequence_length
148
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q14657}. Nucleus {ECO:0000250|UniProtKB:Q14657}.
uniprot
proteins