Psmd11
entrez
69077
canonical
uniprot
Q8BG32
canonical
ensembl
ENSMUSG00000017428
resolver
ensp
ENSMUSP00000017572
resolver
ensp
ENSMUSP00000133571
resolver
enst
ENSMUST00000017572
resolver
enst
ENSMUST00000173938
resolver
genesymbol
Psmd11
resolver
uniprot
Q3UWW9
resolver
uniprot
Q5BKQ9
resolver
uniprot_entry
PSD11_MOUSE
resolver
uniprot_entry
Q3UWW9_MOUSE
resolver
uniprot_entry
Q5BKQ9_MOUSE
resolver
amino_acid_sequence
MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYSKAKKLT
uniprot
proteins
function
FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity. {ECO:0000250|UniProtKB:O00231}.
uniprot
proteins
mass_dalton
47437
uniprot
proteins
protein_family
Proteasome subunit S9 family
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16857966
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
422
uniprot
proteins