KPNA7
entrez
402569
canonical
uniprot
A9QM74
canonical
ensembl
ENSG00000185467
resolver
ensembl
ENSG00000284068
resolver
ensp
ENSP00000330878
resolver
ensp
ENSP00000491331
resolver
ensp
ENSP00000506489
resolver
ensp
ENSP00000563242
resolver
enst
ENST00000327442
resolver
enst
ENST00000640158
resolver
enst
ENST00000681060
resolver
enst
ENST00000893183
resolver
genesymbol
KPNA7
resolver
hgnc
HGNC:21839
resolver
uniprot
A4D277
resolver
uniprot_entry
IMA8_HUMAN
resolver
uniprot_sec
A4D277
resolver
amino_acid_sequence
MPTLDAPEERRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCPDTPSEKTAKGVAVSLTLGEIIKGVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEAAWALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIPHLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLLQHQDSEVLSDACWALSYLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLNVLPQLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFATGATMDQLIQLVHSGVLEPLVNLLTAPDVKIVLIILDVISCILQAAEKRSEKENLCLLIEELGGIDRIEALQLHENRQIGQSALNIIEKHFGEEEDESQTLLSQVIDQDYEFIDYECLAKK
uniprot
proteins
disease_involvement
DISEASE: Oocyte/zygote/embryo maturation arrest 17 (OZEMA17) [MIM:620319]: A rare cause of female primary infertility. In affected women, ovulation and fertilization proceed normally but embryos are arrested at early stages of development or cannot establish pregnancy after implantation. Inheritance is autosomal recessive. {ECO:0000269|PubMed:36647821}. Note=The disease is caused by variants affecting the gene represented in this entry.
uniprot
proteins
function
FUNCTION: Functions in nuclear protein import. {ECO:0000269|PubMed:36647821}.
uniprot
proteins
mass_dalton
56938
uniprot
proteins
protein_family
Importin alpha family
uniprot
proteins
pubmed
12690205
uniprot
proteins
pubmed
20701745
uniprot
proteins
pubmed
36647821
uniprot
proteins
sequence_length
516
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20701745, ECO:0000269|PubMed:36647821}.
uniprot
proteins