Dram1
entrez
71712
canonical
uniprot
Q9DC58
canonical
ensembl
ENSMUSG00000020057
resolver
ensp
ENSMUSP00000020249
resolver
genesymbol
Dram1
resolver
genesymbol_syn
Dram
resolver
uniprot
Q78J26
resolver
uniprot_entry
DRAM1_MOUSE
resolver
uniprot_sec
Q78J26
resolver
amino_acid_sequence
MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVEKQNETCYFSTPVFNLVSLALGLVGCIGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLTTCHVRMAISAVSCAAVVPMIACASLISITKLEWNPKEKDYIYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINDDF
uniprot
proteins
function
FUNCTION: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy (By similarity). {ECO:0000250}.
uniprot
proteins
mass_dalton
26201
uniprot
proteins
protein_family
DRAM/TMEM150 family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
sequence_length
238
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
uniprot
proteins
transmembrane_region
TRANSMEM 9..29; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 53..73; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 91..111; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 116..136; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 161..181; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 200..220; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins