Tmem38a
entrez
306327
canonical
uniprot
A6ZIQ8
canonical
ensembl
ENSRNOG00000011912
resolver
ensp
ENSRNOP00000059284
resolver
ensp
ENSRNOP00000073925
resolver
enst
ENSRNOT00000064060
resolver
enst
ENSRNOT00000086424
resolver
genesymbol
Tmem38a
resolver
uniprot
A0A0G2K6S5
resolver
uniprot
B1WBL7
resolver
uniprot
G3V9T4
resolver
uniprot_entry
A0A0G2K6S5_RAT
resolver
uniprot_entry
B1WBL7_RAT
resolver
uniprot_entry
G3V9T4_RAT
resolver
uniprot_entry
TM38A_RAT
resolver
activity_regulation
ACTIVITY REGULATION: Channel activity is activated by a change of voltage within the sarcoplasmic reticulum lumen and blocked by luminal high Ca(2+) levels. {ECO:0000250|UniProtKB:A5A6S6}.
uniprot
proteins
amino_acid_sequence
MDLISSLSLGELALSFSRVPLFPVFDLSYFIVSIIYLKYEPGSVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHYHHGWFIMIATGWVKGSGVALLSNLEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFVFTMFMVSCKVFLTATHSHSSPFDVLEGYICPVLFGATWGGDHHHDNHGAPHGMGLGTQHSGLPAKAKEELSEGFRKKKTKKAD
uniprot
proteins
function
FUNCTION: Intracellular monovalent cation channel required for maintenance of rapid intracellular calcium release. Acts as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. Opened by a change of voltage within the sarcoplasmic reticulum lumen. {ECO:0000250|UniProtKB:A5A6S6}.
uniprot
proteins
mass_dalton
33276
uniprot
proteins
protein_family
TMEM38 family
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:A5A6S6}; Multi-pass membrane protein {ECO:0000250|UniProtKB:A5A6S6}. Nucleus membrane {ECO:0000250|UniProtKB:A5A6S6}.
uniprot
proteins
transmembrane_region
TRANSMEM 19..39; /note="Helical;Name=1"; /evidence="ECO:0000255"; TRANSMEM 52..72; /note="Helical;Name=2"; /evidence="ECO:0000255"; TRANSMEM 86..106; /note="Helical;Name=3"; /evidence="ECO:0000255"; TRANSMEM 144..164; /note="Helical;Name=4"; /evidence="ECO:0000255"; TRANSMEM 178..198; /note="Helical;Name=5"; /evidence="ECO:0000255"; TRANSMEM 209..229; /note="Helical;Name=6"; /evidence="ECO:0000255"; TRANSMEM 234..254; /note="Helical;Name=7"; /evidence="ECO:0000255
uniprot
proteins