PLSCR2
entrez
57047
canonical
uniprot
Q9NRY7
canonical
ensembl
ENSG00000163746
resolver
ensp
ENSP00000338707
resolver
ensp
ENSP00000420132
resolver
ensp
ENSP00000478902
resolver
ensp
ENSP00000512407
resolver
ensp
ENSP00000512413
resolver
ensp
ENSP00000512414
resolver
genesymbol
PLSCR2
resolver
hgnc
HGNC:16494
resolver
uniprot
B4DXC3
resolver
uniprot
J3KR76
resolver
uniprot
Q0VAQ1
resolver
uniprot
Q6NSW9
resolver
uniprot
Q7Z4L7
resolver
uniprot_entry
PLS2_HUMAN
resolver
uniprot_sec
B4DXC3
resolver
uniprot_sec
J3KR76
resolver
uniprot_sec
Q0VAQ1
resolver
uniprot_sec
Q6NSW9
resolver
uniprot_sec
Q7Z4L7
resolver
amino_acid_sequence
MRSWNSLFCLNSSRPPGHIVYPKHQAGHTGKQADHLGSQAFYPGRQHDYLVPPAGTAGIPVQNQPGRPEGVPWMPAPPPPLNCPPGLEYLSQIDMILIHQQIELLEVLFSFESSNMYEIKNSFGQRIYFAAEDTNFCIRNCCGRSRPFTLRITDNVGREVITLERPLRCNCCCCPCCLQEIEIQAPPGVPVGYVTQTWHPCLTKFTIKNQKREDVLKISGPCIVCSCIAGVDFEITSLDEQIVVGRISKHWSGFLREAFTDADNFGIQFPRDLDVKMKAVMIGACFLIDYMFFERTR
uniprot
proteins
function
FUNCTION: May catalyze calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane. {ECO:0000305|PubMed:24648509}.; FUNCTION: [Isoform 1]: Has no phospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain. {ECO:0000269|PubMed:24648509}.
uniprot
proteins
mass_dalton
33504
uniprot
proteins
protein_family
Phospholipid scramblase family
uniprot
proteins
pubmed
10930526
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16641997
uniprot
proteins
pubmed
24648509
uniprot
proteins
sequence_length
297
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:O15162}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O15162}.; SUBCELLULAR LOCATION: [Isoform 1]: Nucleus {ECO:0000269|PubMed:24648509}.
uniprot
proteins
transmembrane_region
TRANSMEM 277..293; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins