Ccne1
entrez
12447
canonical
uniprot
Q61457
canonical
ensembl
ENSMUSG00000002068
resolver
ensp
ENSMUSP00000103658
resolver
enst
ENSMUST00000108023
resolver
genesymbol
Ccne1
resolver
genesymbol_syn
Ccne
resolver
uniprot
Q05BA1
resolver
uniprot
Q05BA6
resolver
uniprot
Q05BB7
resolver
uniprot_entry
CCNE1_MOUSE
resolver
uniprot_sec
Q05BA1
resolver
uniprot_sec
Q05BA6
resolver
uniprot_sec
Q05BB7
resolver
amino_acid_sequence
MPRERDSTDHSNMKEEGGSDLSVRSRKRKANVAVFLQDPDEEIAKIDKTVKSEDSSQPWDDNSACVDPCSFIPTPNKEEDNELEYPRTAFQPRKIRPPRASPLPVLNWGNREEVWRIMLNKEKTYLRDEHFLQRHPLLQARMRAVLLDWLMEVCEVYKLHRETFYLAQDFFDRYMASQHNIIKTLLQLIGISALFIASKLEEIYPPKLHQFAYVTDGACSGDEILTMELMMMKALKWRLSPLTIVSWLNVYVQVAYVNDTGEVLMPQYPQQVFVQIAELLDLCVLDVGCLEFPYGVLAASALYHFSSLELMQKVSGYQWCDIEKCVKWMVPFAMVIREMGSSKLKHFRGVPMEDSHNIQTHTNSLDLLDKAQAKKAILSEQNRISPPPSVVLTPPPSSKKQSSEQETE
uniprot
proteins
function
FUNCTION: Essential for the control of the cell cycle at the G1/S (start) transition.
uniprot
proteins
mass_dalton
46986
uniprot
proteins
post_translational_modification
PTM: Phosphorylation of both Thr-393 by GSK3 and Ser-397 by CDK2 creates a high affinity degron recognized by FBXW7, and accelerates degradation via the ubiquitin proteasome pathway. Phosphorylation at Thr-74 creates a low affinity degron also recognized by FBXW7 (By similarity). {ECO:0000250|UniProtKB:P24864}.; PTM: Ubiquitinated by UHRF2; appears to occur independently of phosphorylation. {ECO:0000250|UniProtKB:P24864}.
uniprot
proteins
protein_family
Cyclin E subfamily
uniprot
proteins
protein_family
Cyclin family
uniprot
proteins
pubmed
11585773
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
8003041
uniprot
proteins
sequence_length
408
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P24864}.
uniprot
proteins