APBB2
entrez
323
canonical
uniprot
Q92870
canonical
ensembl
ENSG00000163697
resolver
ensp
ENSP00000295974
resolver
ensp
ENSP00000421539
resolver
ensp
ENSP00000423765
resolver
ensp
ENSP00000425802
resolver
ensp
ENSP00000426018
resolver
ensp
ENSP00000427211
resolver
ensp
ENSP00000427307
resolver
ensp
ENSP00000564709
resolver
ensp
ENSP00000564711
resolver
ensp
ENSP00000582420
resolver
ensp
ENSP00000582421
resolver
ensp
ENSP00000653776
resolver
ensp
ENSP00000716516
resolver
enst
ENST00000506352
resolver
genesymbol
APBB2
resolver
genesymbol_syn
FE65L
resolver
genesymbol_syn
FE65L1
resolver
hgnc
HGNC:582
resolver
uniprot
B4DJ88
resolver
uniprot
B4DSL4
resolver
uniprot
B4E2F2
resolver
uniprot
E9PG87
resolver
uniprot
G5E9Y1
resolver
uniprot
Q5I0G1
resolver
uniprot
Q8IUI6
resolver
uniprot_entry
APBB2_HUMAN
resolver
uniprot_entry
B4DJ88_HUMAN
resolver
uniprot_entry
B4E2F2_HUMAN
resolver
uniprot_entry
G5E9Y1_HUMAN
resolver
uniprot_entry
Q5I0G1_HUMAN
resolver
uniprot_sec
B4DSL4
resolver
uniprot_sec
E9PG87
resolver
uniprot_sec
Q8IUI6
resolver
amino_acid_sequence
MSEVLPADSGVDTLAVFMASSGTTDVTNRNSPATPPNTLNLRSSHNELLNAEIKHTETKNSTPPKCRKKYALTNIQAAMGLSDPAAQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNKNLSPTAVINITSEKLEGKEPHPQDSSSCEILPSQPRRTKSFLNYYADLETSARELEQNRGNHHGTAEEKSQPVQGQASTIIGNGDLLLQKPNRPQSSPEDGQVATVSSSPETKKDHPKTGAKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETDIWSDHSFQTDPDLPPGWKRVSDIAGTYYWHIPTGTTQWERPVSIPADLQGSRKGSLSSVTPSPTPENEKQPWSDFAVLNGGKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHPDDDDSCSINSDPEAKCFAVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLILENDMLSLVDPMDRSVLHSQPIVSIRVWGVGRDNGRDFAYVARDKDTRILKCHVFRCDTPAKAIATSLHEICSKIMAERKNAKALACSSLQERANVNLDVPLQVDFPTPKTELVQKFHVQYLGMLPVDKPVGMDILNSAIENLMTSSNKEDWLSVNMNVADATVTVISEKNEEEVLVECRVRFLSFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAGNVSEAVQAACMLRYQKCLVARPPSQKVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTEMP
uniprot
proteins
function
FUNCTION: Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (By similarity). Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning (By similarity). Activates transcription of APP (PubMed:14527950). {ECO:0000250|UniProtKB:Q9DBR4, ECO:0000269|PubMed:14527950}.
uniprot
proteins
mass_dalton
83374
uniprot
proteins
mutagenesis
MUTAGEN 702; /note="C->V: Abolishes interaction with APP and gamma-secretase-dependent processing of the APP membrane-anchored C-terminal fragment C83."; /evidence="ECO:0000269|PubMed:14527950
uniprot
proteins
pubmed
14527950
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
19413330
uniprot
proteins
pubmed
19690332
uniprot
proteins
pubmed
20068231
uniprot
proteins
pubmed
21406692
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
8855266
uniprot
proteins
sequence_length
758
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:14527950}. Golgi apparatus {ECO:0000269|PubMed:14527950}. Early endosome {ECO:0000269|PubMed:14527950}.
uniprot
proteins