Shprh
entrez
268281
canonical
uniprot
Q7TPQ3
canonical
ensembl
ENSMUSG00000090112
resolver
ensp
ENSMUSP00000039422
resolver
ensp
ENSMUSP00000125849
resolver
ensp
ENSMUSP00000132870
resolver
ensp
ENSMUSP00000247043
resolver
genesymbol
Shprh
resolver
uniprot
Q7TQ27
resolver
uniprot
Q7TQ28
resolver
uniprot
Q7TQ29
resolver
uniprot
Q8BKE2
resolver
uniprot
Q8BUW0
resolver
uniprot
Q922Q3
resolver
uniprot_entry
SHPRH_MOUSE
resolver
uniprot_sec
Q7TQ27
resolver
uniprot_sec
Q7TQ28
resolver
uniprot_sec
Q7TQ29
resolver
uniprot_sec
Q8BKE2
resolver
uniprot_sec
Q8BUW0
resolver
uniprot_sec
Q922Q3
resolver
amino_acid_sequence
MSSRRKRAPPMKVDEERQQQLHWNMHEDLRSEPLTMTVGEQACSDADSSSDCIIIDEGPPESALHRDKKRRSETVSVLEATEEETRLSVTLNVTVSPYRVDNSWKAFLGDFALQLLPKESLVEHFSERTFTLSPSESSSQFLIYVHSECKNVEKQENVLEGSAGVCSKGIRVESSFSSDMLQDLAWLQKRRGIKLYQRPDGTHTIKVGIYILEAGLTRLDFMSDAGSRMKKFNQLMKRVMEKLHNFIIPDVLEEEEEGSESEPEGQDIDELYHFVKQTHQQETRSVQVDVQHPALIPVLRPYQREAVNWMLQQEQFRSAPPADNSLHFLWREIVTPDGLKLYYNPYTGCIIRDFPHAGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPTHCPREKVKNREIQDTEYEPKEKVHCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIFRYDVQRNRGLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEDVFDKTKKQAVGSPRKIEKELRKSVNKDADSEYLPSNTSDDDEPYYYYCKAGKSRSKLKKPALLTKKGKGQSVHLDSQGDAPAAGVCASTDVHVSENTCVSEDKQTQEAKDCAESPNPAAEELAQSNTSSPCETSDYRFECICGEFDQIGHKPRVQCLKCHLWQHAKCVNYEEKNLKVKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKHGFLQPHFLAEQDIVIITYDVLRSELNYVNIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWIRLLYHPYCKKNPQHLYSFIAKIMWRSAKKDVIDQIQIPPQTEEMHWLHFSPVERHFYHRQHEVCCQDAIVKLRKISDWALKLSSLDRRTVSSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLGAKHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALQPVQQSIRELQRKIHSNSPWWLNVIHRAMEFSVDEELVQRVRNEISSNYKQQTDKLSMSEKFRDCRGLQFLLTTQMEELHKFQKLVREAVKKLEKPPSREVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFFNTVKGQTAIFEEMIEDEEGLVDDRVPTTTRGLWAVSETERSMKAILSFARSHRFDVEYVDEGSVSMDLFEAWKKEYKLLHEYWMTLRNRVSAVDELAMATERLRVRHPKEPKPNPPVHHIIEPHEVEQNRIKLVNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGINPEPCPICARQLGKQWAVLTCGHCFCNECTSIIIEQYSVGSHRSSIKCAICRQTTSHKEVSYVFTSEKANQEDDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFTQISRIKTFQENLSAFKYDPHINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTSSSGKHSEASVLTVAGLADLFTKENEELE
uniprot
proteins
ec_number
2.3.2.27
uniprot
proteins
ec_number
3.6.4.-
uniprot
proteins
function
FUNCTION: E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'. {ECO:0000250|UniProtKB:Q149N8}.
uniprot
proteins
mass_dalton
191490
uniprot
proteins
pathway_participation
PATHWAY: Protein modification; protein ubiquitination.
uniprot
proteins
protein_family
SNF2/RAD54 helicase family
uniprot
proteins
pubmed
12837266
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
sequence_length
1674
uniprot
proteins