Sohlh2
entrez
74434
canonical
uniprot
Q9D489
canonical
ensembl
ENSMUSG00000027794
resolver
ensp
ENSMUSP00000029369
resolver
enst
ENSMUST00000029369
resolver
genesymbol
Sohlh2
resolver
genesymbol_syn
Tohlh2
resolver
uniprot
Q4JI40
resolver
uniprot_entry
SOLH2_MOUSE
resolver
uniprot_sec
Q4JI40
resolver
amino_acid_sequence
MADRISTGELGRRPGQGRVNLLLVGDATRYFLAGSMQKFFPSTAQITLTISNVKKVAVLLAANSFDIIFLKVTSTLTAEEQEAAKLIRSGKKKNTHLLFAFVIPERLKGYVSEYGADISFSEPLTLEKVNTVIHYWKTYFTNTDMENTELPPECRLYFQTSRSELGGRFSTDMFLCSELLKNDARLGLKAPLSSLDKSKQASFLHSTKEKLRRERIKSCCEQLRTLLPYVKGRKSDVASVIEATVDYVKQVRESLSPAIMAQVTEAIQNNRRFSKRQMPIELFLPFSATSQREDAMLTSAFSPVQEIQLLADRGLNVYSMTAAGGALEGAVRGQPGSVSESSIEDLYKTRVPSTARSLNSFHSVKYTSGTVSPHEAAARTNQNISTYLPPTAPSVSNFIPQHCNAMLCPARPTSPNCLCTPGHELAASSRAASASIFRGFRAASASDHQASQPPALPSPQPHDSSYF
uniprot
proteins
function
FUNCTION: Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation (PubMed:22056784). Coordinates oocyte differentiation without affecting meiosis I (PubMed:28504655). {ECO:0000269|PubMed:22056784, ECO:0000269|PubMed:28504655}.
uniprot
proteins
mass_dalton
51325
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
16564520
uniprot
proteins
pubmed
16765102
uniprot
proteins
pubmed
22056784
uniprot
proteins
pubmed
28504655
uniprot
proteins
sequence_length
467
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:16765102, ECO:0000269|PubMed:28504655}. Cytoplasm {ECO:0000269|PubMed:28504655}. Note=Translocates from the cytoplasm into the nucleus and the translocation is dependent on SOHLH1 protein expression. {ECO:0000269|PubMed:28504655}.
uniprot
proteins