Q62935
uniprot
Q62935
canonical
amino_acid_sequence
HCDGVNLTCEACQEPGGLVVPPTDAPVSSTTPYVEDTPEPPLHNFYCSKLLDLVFLLDGSYRLSEAEFEVLKAFVVGTMERLHISQKRIRVAVVEYHDGSHAYLELRARKRPSELRRIASQIKYVGSQLASTSEVLKYTLFQIFGKIDRPEASRVILLLTASQEPQRMARYFTRYLQGFKKKKVILIPVGIGPHANLKQIRLIEKQAPENKAFLLSGVDELEQRRDEIINYLCDLAPEAPAPSKPPQVAHITVSPGISGVSSPGPKRKSLVLDVVFVLEASDEVGEANFNKSKEFLEEVIQRMDVSPAGTHIAVLQYSYTVNVEYTFKEAQSKEDVLRHVREIRYQGGNRTNTGQALQYLSEHSFSPSQGDREQAPNLVYMVTGNPASDEIRRLPGDIQVVPIGVGSRANLQELERISRPITPIFIQDFE
uniprot
proteins
function
FUNCTION: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). {ECO:0000250|UniProtKB:P04275}.
uniprot
proteins
mass_dalton
48139
uniprot
proteins
post_translational_modification
PTM: N- and O-glycosylated. {ECO:0000250}.
uniprot
proteins
pubmed
10335651
uniprot
proteins
pubmed
12871266
uniprot
proteins
sequence_length
430
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Localized to storage granules. {ECO:0000250}.
uniprot
proteins