PCYOX1
entrez
51449
canonical
uniprot
Q9UHG3
canonical
ensembl
ENSG00000116005
resolver
ensp
ENSP00000387654
resolver
genesymbol
PCYOX1
resolver
genesymbol_syn
KIAA0908
resolver
genesymbol_syn
PCL1
resolver
hgnc
HGNC:20588
resolver
uniprot
B2RB14
resolver
uniprot
B7Z9P8
resolver
uniprot
O94982
resolver
uniprot
Q8N4N5
resolver
uniprot
Q96QM8
resolver
uniprot_entry
PCYOX_HUMAN
resolver
uniprot_sec
B2RB14
resolver
uniprot_sec
B7Z9P8
resolver
uniprot_sec
O94982
resolver
uniprot_sec
Q8N4N5
resolver
uniprot_sec
Q96QM8
resolver
amino_acid_sequence
MGRVVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAIIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSAVQASGGLLGIYNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL
uniprot
proteins
ec_number
1.8.3.5
uniprot
proteins
function
FUNCTION: Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (PubMed:10585463, PubMed:11078725, PubMed:12186880). Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity). Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded (PubMed:10585463). {ECO:0000250|UniProtKB:F1N2K1, ECO:0000269|PubMed:10585463, ECO:0000269|PubMed:11078725, ECO:0000269|PubMed:12186880}.
uniprot
proteins
mass_dalton
56640
uniprot
proteins
protein_family
Prenylcysteine oxidase family
uniprot
proteins
pubmed
10048485
uniprot
proteins
pubmed
10585463
uniprot
proteins
pubmed
11078725
uniprot
proteins
pubmed
12186880
uniprot
proteins
pubmed
12975309
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15815621
uniprot
proteins
pubmed
16335952
uniprot
proteins
pubmed
19159218
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
24275569
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
505
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Lysosome {ECO:0000269|PubMed:10585463}.
uniprot
proteins