TYW1
entrez
55253
canonical
uniprot
Q9NV66
canonical
ensembl
ENSG00000198874
resolver
ensp
ENSP00000352645
resolver
ensp
ENSP00000725586
resolver
ensp
ENSP00000725587
resolver
ensp
ENSP00000788216
resolver
genesymbol
TYW1
resolver
genesymbol_syn
RSAFD1
resolver
hgnc
HGNC:25598
resolver
uniprot
Q6PJG8
resolver
uniprot
Q75MG8
resolver
uniprot
Q75MN3
resolver
uniprot
Q86V12
resolver
uniprot
Q8IVS7
resolver
uniprot
Q9H9C4
resolver
uniprot_entry
TYW1_HUMAN
resolver
uniprot_sec
Q6PJG8
resolver
uniprot_sec
Q75MG8
resolver
uniprot_sec
Q75MN3
resolver
uniprot_sec
Q86V12
resolver
uniprot_sec
Q8IVS7
resolver
uniprot_sec
Q9H9C4
resolver
amino_acid_sequence
MDPSADTWDLFSPLISLWINRFYIYLGFAVSISLWICVQIVIKTQGKNLQEKSVPKAAQDLMTNGYVSLQEKDIFVSGVKIFYGSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRYAVFGLGNSAYASHFNKVGKNVDKWLWMLGAHRVMSRGEGDCDVVKSKHGSIEADFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSHEQDELHHRDTEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCGESSASSLTMAHVPWHEEVVQFVHELVDLIPEYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGASERGFDPKDTRHQRKNKSKAISGC
uniprot
proteins
ec_number
4.1.3.44
uniprot
proteins
function
FUNCTION: Involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis. {ECO:0000250|UniProtKB:Q08960}.
uniprot
proteins
mass_dalton
83702
uniprot
proteins
pathway_participation
PATHWAY: tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
uniprot
proteins
protein_family
TYW1 family
uniprot
proteins
pubmed
12853948
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
sequence_length
732
uniprot
proteins