Pon1
entrez
18979
canonical
uniprot
P52430
canonical
ensembl
ENSMUSG00000002588
resolver
ensp
ENSMUSP00000002663
resolver
ensp
ENSMUSP00000135195
resolver
ensp
ENSMUSP00000315730
resolver
ensp
ENSMUSP00000350455
resolver
enst
ENSMUST00000002663
resolver
genesymbol
Pon1
resolver
genesymbol_syn
Pon
resolver
uniprot
Q91X30
resolver
uniprot_entry
PON1_MOUSE
resolver
uniprot_sec
Q91X30
resolver
amino_acid_sequence
MAKLLALTLVGLVLALYKNHRSSYQTRLNAFREVTPVELPNCNLVKGIETGAEDLEILPNGLTFFSTGLKYPGIKSFDPSKPGKILLMDLNKKEPAVSELEIIGNTLDISSFNPHGISTFTDEDNTVYLLVVNHPDSSSTVEVFKFQEEERSLLHLKTITHELLPSINDIAAIGPESFYATNDHYFADPYLRSWEMYLGLSWSNVVYYSPDKVQVVAEGFDFANGIGISLDGKYVYIAELLAHKIHVYEKHANWTLTPLKVLNFDTLVDNISVDPVTGDLWVGCHPNGMRIFFYDAENPPGSEVLRIQNILSEDPKITVVYAENGTVLQGTTVASVYKGKLLIGTVFHKALYCDL
uniprot
proteins
ec_number
3.1.1.2
uniprot
proteins
ec_number
3.1.1.81
uniprot
proteins
ec_number
3.1.8.1
uniprot
proteins
function
FUNCTION: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification. {ECO:0000250|UniProtKB:P27169}.
uniprot
proteins
mass_dalton
39565
uniprot
proteins
post_translational_modification
PTM: The signal sequence is not cleaved. {ECO:0000250|UniProtKB:P27169}.
uniprot
proteins
protein_family
Paraoxonase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
15963993
uniprot
proteins
pubmed
17330941
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
7638166
uniprot
proteins
pubmed
8601628
uniprot
proteins
pubmed
9170151
uniprot
proteins
sequence_length
355
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space.
uniprot
proteins