Gsr
entrez
14782
canonical
uniprot
P47791
canonical
ensembl
ENSMUSG00000031584
resolver
ensp
ENSMUSP00000033992
resolver
genesymbol
Gsr
resolver
genesymbol_syn
Gr1
resolver
uniprot
Q7TNC2
resolver
uniprot
Q8BN97
resolver
uniprot
Q8C9Z6
resolver
uniprot_entry
GSHR_MOUSE
resolver
uniprot_sec
Q7TNC2
resolver
uniprot_sec
Q8BN97
resolver
uniprot_sec
Q8C9Z6
resolver
amino_acid_sequence
MALLPRALGVGAAPSLRRAARALTCAMASPGEPQPPAPDTSSFDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHVDYGFQSCEGKFSWHVIKQKRDAYVSRLNTIYQNNLTKSHIEIIHGYATFADGPRPTVEVNGKKFTAPHILIATGGVPTVPHESQIPGASLGITSDGFFQLEDLPSRSVIVGAGYIAVEIAGILSALGSKTSLMIRHDKVLRNFDSLISSNCTEELENAGVEVLKFTQVKEVKKTSSGLELQVVTSVPGRKPTTTMIPDVDCLLWAIGRDPNSKGLNLNKVGIQTDEKGHILVDEFQNTNVKGVYAVGDVCGKALLTPVAIAAGRKLAHRLFECKQDSKLDYDNIPTVVFSHPPIGTVGLTEDEAVHKYGKDNVKIYSTAFTPMYHAVTTRKTKCVMKMVCANKEEKVVGIHMQGIGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
uniprot
proteins
ec_number
1.8.1.7
uniprot
proteins
function
FUNCTION: Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol. {ECO:0000250|UniProtKB:P00390}.
uniprot
proteins
mass_dalton
53663
uniprot
proteins
protein_family
Class-I pyridine nucleotide-disulfide oxidoreductase family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
21183079
uniprot
proteins
pubmed
2185014
uniprot
proteins
pubmed
23576753
uniprot
proteins
pubmed
9268726
uniprot
proteins
sequence_length
500
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: [Isoform Mitochondrial]: Mitochondrion {ECO:0000250|UniProtKB:P00390}.; SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm {ECO:0000250|UniProtKB:P00390}.
uniprot
proteins