GOLPH3L
entrez
55204
canonical
uniprot
Q9H4A5
canonical
ensembl
ENSG00000143457
resolver
ensp
ENSP00000271732
resolver
ensp
ENSP00000664824
resolver
genesymbol
GOLPH3L
resolver
genesymbol_syn
GPP34R
resolver
hgnc
HGNC:24882
resolver
uniprot
B1AN09
resolver
uniprot
B7Z6N3
resolver
uniprot
Q9NVK0
resolver
uniprot_entry
GLP3L_HUMAN
resolver
uniprot_sec
B1AN09
resolver
uniprot_sec
B7Z6N3
resolver
uniprot_sec
Q9NVK0
resolver
amino_acid_sequence
MTTLTHRARRTEISKNSEKKMESEEDSNWEKSPDNEDSGDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKKRLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLVKKLQDSVLERWVNDPQRMDKRTLALLVLAHSSDVLENVFSSLTDDKYDVAMNRAKDLVELDPEVEGTKPSATEMIWAVLAAFNKS
uniprot
proteins
function
FUNCTION: Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane. {ECO:0000269|PubMed:23345592}.
uniprot
proteins
mass_dalton
32767
uniprot
proteins
mutagenesis
MUTAGEN 7..10; /note="RARR->AAAA: Loss of binding to coatomer."; /evidence="ECO:0000269|PubMed:22889169
uniprot
proteins
protein_family
GOLPH3/VPS74 family
uniprot
proteins
pubmed
11042173
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16710414
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
22889169
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
23345592
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
285
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Note=Phosphatidylinositol 4-phosphate (PtdIns4P)-binding mediates recruitment to Golgi membranes.
uniprot
proteins