Try4
entrez
22074
canonical
uniprot
Q9R0T7
canonical
ensembl
ENSMUSG00000054106
resolver
ensp
ENSMUSP00000031913
resolver
enst
ENSMUST00000031913
resolver
genesymbol
Try4
resolver
genesymbol_syn
T8
resolver
genesymbol_syn
Td
resolver
uniprot_entry
TRY4_MOUSE
resolver
activity_regulation
ACTIVITY REGULATION: Activated by autocatalytic cleavage (PubMed:23814066). Cleavage by CTRC inhibits autoactivation (PubMed:23814066). {ECO:0000269|PubMed:23814066}.
uniprot
proteins
amino_acid_sequence
MRALLFLALVGAAVAFPVDDDDKIVGGYTCRENSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGNEQFVNSAKIIKHPNFNSRTLNNDIMLIKLASPVTLNARVATVALPSSCAPAGTQCLISGWGNTLSFGVNNPDLLQCLDAPLLPQADCEASYPGKITNNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALKDNPGVYTKVCNYVDWIQNTIAAN
uniprot
proteins
ec_number
3.4.21.4
uniprot
proteins
function
FUNCTION: Serine protease capable of autoactivation. {ECO:0000269|PubMed:23814066}.
uniprot
proteins
mass_dalton
26274
uniprot
proteins
mutagenesis
MUTAGEN 122; /note="R->H: Slightly increases autoactivation."; /evidence="ECO:0000269|PubMed:23814066
uniprot
proteins
post_translational_modification
PTM: Proteolytically cleaved and activated by an autocatalytic mechanism (PubMed:23814066). Cleavage by CTRC inhibits autoactivation (PubMed:23814066). {ECO:0000269|PubMed:23814066}.
uniprot
proteins
protein_family
Peptidase S1 family
uniprot
proteins
pubmed
10506205
uniprot
proteins
pubmed
11160223
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16141072
uniprot
proteins
pubmed
19468303
uniprot
proteins
pubmed
23814066
uniprot
proteins
sequence_length
246
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000305}.
uniprot
proteins