MTHFD1L
entrez
25902
canonical
uniprot
Q6UB35
canonical
ensembl
ENSG00000120254
resolver
ensp
ENSP00000356276
resolver
ensp
ENSP00000356290
resolver
ensp
ENSP00000478253
resolver
ensp
ENSP00000479539
resolver
ensp
ENSP00000657931
resolver
ensp
ENSP00000716562
resolver
ensp
ENSP00000751792
resolver
enst
ENST00000611279
resolver
enst
ENST00000618312
resolver
genesymbol
MTHFD1L
resolver
genesymbol_syn
FTHFSDC1
resolver
hgnc
HGNC:21055
resolver
uniprot
A0A087WTZ6
resolver
uniprot
A0A087WVM4
resolver
uniprot
B2RD24
resolver
uniprot
B7ZM99
resolver
uniprot
Q2TBF3
resolver
uniprot
Q8WVW0
resolver
uniprot
Q96HG8
resolver
uniprot
Q9H789
resolver
uniprot
Q9UFU8
resolver
uniprot_entry
A0A087WTZ6_HUMAN
resolver
uniprot_entry
A0A087WVM4_HUMAN
resolver
uniprot_entry
B2RD24_HUMAN
resolver
uniprot_entry
B7ZM99_HUMAN
resolver
uniprot_entry
C1TM_HUMAN
resolver
uniprot_sec
Q2TBF3
resolver
uniprot_sec
Q8WVW0
resolver
uniprot_sec
Q96HG8
resolver
uniprot_sec
Q9H789
resolver
uniprot_sec
Q9UFU8
resolver
amino_acid_sequence
MGTRLPLVLRQLRRPPQPPGPPRRLRVPCRASSGGGGGGGGGREGLLGQRRPQDGQARSSCSPGGRTPAARDSIVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAGDDNLMQEINQNLAEEAGLNITHICLPPDSSEAEIIDEILKINEDTRVHGLALQISENLFSNKVLNALKPEKDVDGVTDINLGKLVRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSIQWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNCSHDFLSGKVGCGSPRIHFGGLIEEDDVILLAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVPSDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVRLSVLERLKDQADGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHENTQTDKALYNRLVPLVNGVREFSEIQLARLKKLGINKTDPSTLTEEEVSKFARLDIDPSTITWQRVLDTNDRFLRKITIGQGNTEKGHYRQAQFDIAVASEIMAVLALTDSLADMKARLGRMVVASDKSGQPVTADDLGVTGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGADIGMEKFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEENIQLVADGCCNLQKQIQITQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSVGGKGSVDLARAVREAASKRSRFQFLYDVQVPIVDKIRTIAQAVYGAKDIELSPEAQAKIDRYTQQGFGNLPICMAKTHLSLSHQPDKKGVPRDFILPISDVRASIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDTETEQVKGLF
uniprot
proteins
ec_number
6.3.4.3
uniprot
proteins
function
FUNCTION: May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2. {ECO:0000250, ECO:0000269|PubMed:16171773}.
uniprot
proteins
mass_dalton
105790
uniprot
proteins
pathway_participation
PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion. {ECO:0000269|PubMed:16171773}.
uniprot
proteins
protein_family
Tetrahydrofolate dehydrogenase/cyclohydrolase family; Formate--tetrahydrofolate ligase family
uniprot
proteins
pubmed
12937168
uniprot
proteins
pubmed
14574404
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15013446
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
16171773
uniprot
proteins
pubmed
16959974
uniprot
proteins
pubmed
17974005
uniprot
proteins
pubmed
19608861
uniprot
proteins
pubmed
21269460
uniprot
proteins
pubmed
23186163
uniprot
proteins
pubmed
25944712
uniprot
proteins
sequence_length
978
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:12937168}.
uniprot
proteins