SPMIP6
entrez
84688
canonical
uniprot
Q8NCR6
canonical
ensembl
ENSG00000164972
resolver
ensp
ENSP00000297623
resolver
ensp
ENSP00000368421
resolver
ensp
ENSP00000368422
resolver
ensp
ENSP00000368428
resolver
ensp
ENSP00000510469
resolver
enst
ENST00000692548
resolver
genesymbol
SPMIP6
resolver
genesymbol_syn
C9orf24
resolver
genesymbol_syn
CBE1
resolver
genesymbol_syn
SMRP1
resolver
hgnc
HGNC:19919
resolver
uniprot
A0A8I5KRB0
resolver
uniprot
Q5T598
resolver
uniprot
Q5T599
resolver
uniprot
Q5T5A0
resolver
uniprot
Q8N9G4
resolver
uniprot
Q96KD1
resolver
uniprot
Q96LN1
resolver
uniprot_entry
A0A8I5KRB0_HUMAN
resolver
uniprot_entry
SMIP6_HUMAN
resolver
uniprot_sec
Q5T598
resolver
uniprot_sec
Q5T599
resolver
uniprot_sec
Q5T5A0
resolver
uniprot_sec
Q8N9G4
resolver
uniprot_sec
Q96KD1
resolver
uniprot_sec
Q96LN1
resolver
amino_acid_sequence
MFLFSRKTRTPISTYSDSYRAPTSIKEVYKDPPLCAWEANKFLTPGLTHTMERHVDPEALQKMAKCAVQDYTYRGSISGHPYLPEKYWLSQEEADKCSPNYLGSDWYNTWRMEPYNSSCCNKYTTYLPRLPKEARMETAVRGMPLECPPRPERLNAYEREVMVNMLNSLSRNQQLPRITPRCGCVDPLPGRLPFHGYESACSGRHYCLRGMDYYASGAPCTDRRLRPWCREQPTMCTSLRAPARNAVCCYNSPAVILPISEP
uniprot
proteins
function
FUNCTION: May participate in intramanchette transport and midpiece formation of the sperm tail. May play a potential role in somatic cell proliferation. {ECO:0000250|UniProtKB:Q2MH31}.
uniprot
proteins
mass_dalton
30167
uniprot
proteins
mutagenesis
MUTAGEN 223..224; /note="RR->AA: Predominantly cytoplasmic rather than nuclear localization."; /evidence="ECO:0000269|PubMed:15242845
uniprot
proteins
protein_family
SPMIP6 family
uniprot
proteins
pubmed
14702039
uniprot
proteins
pubmed
15164053
uniprot
proteins
pubmed
15242845
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
19213785
uniprot
proteins
pubmed
28601408
uniprot
proteins
sequence_length
262
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q2MH31}. Nucleus {ECO:0000269|PubMed:15242845}. Cytoplasm {ECO:0000269|PubMed:15242845}. Mitochondrion {ECO:0000250|UniProtKB:Q2MH31}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:28601408}. Note=During spermatid elongation (step 10), localizes along the length of the manchette and later during the elongation process only at the distal ends of spermatid manchette (step 12). In late elongated spermatids (step 16), in the final steps of spermiogenesis, localization is restricted to the midpiece of the flagellum. Localizes at the contractile ring in dividing cells (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines (PubMed:15242845). {ECO:0000250|UniProtKB:Q2MH31, ECO:0000269|PubMed:15242845}.
uniprot
proteins