Btn1a1
entrez
12231
canonical
uniprot
Q62556
canonical
ensembl
ENSMUSG00000000706
resolver
ensp
ENSMUSP00000041013
resolver
enst
ENSMUST00000041674
resolver
genesymbol
Btn1a1
resolver
genesymbol_syn
Btn
resolver
uniprot
P97392
resolver
uniprot
Q3UM26
resolver
uniprot
Q3UQC0
resolver
uniprot
Q8K2H7
resolver
uniprot
Q921K7
resolver
uniprot_entry
BT1A1_MOUSE
resolver
uniprot_entry
Q3UM26_MOUSE
resolver
uniprot_entry
Q3UQC0_MOUSE
resolver
uniprot_sec
P97392
resolver
uniprot_sec
Q8K2H7
resolver
uniprot_sec
Q921K7
resolver
amino_acid_sequence
MAVPTNSCLLVCLLTLTVLQLPTLDSAAPFDVTAPQEPVLALVGSDAELTCGFSPNASSEYMELLWFRQTRSTAVLLYRDGQEQEGQQMTEYRGRATLATAGLLDGRATLLIRDVRVSDQGEYRCLFKDNDDFEEAAVYLKVAAVGSDPQISMTVQENGEMELECTSSGWYPEPQVQWRTGNREMLPSTSESKKHNEEGLFTVAVSMMIRDSSIKNMSCCIQNILLGQGKEVEISLPAPFVPRLTPWIVAVAIILLALGFLTIGSIFFTWKLYKERSSLRKKEFGSKERLLEELRCKKTVLHEVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQILPDRPERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCRENVVKKGFDPMTPDNGFWAVELYGNGYWALTPLRTSLRLAGPPRRVGVFLDYDAGDISFYNMSNGSLIYTFPSISFSGPLRPFFCLWSCGKKPLTICSTANGPEKVTVIANVQDDIPLSPLGEGCTSGDKDTLHSKLIPFSPSQAAP
uniprot
proteins
function
FUNCTION: May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. {ECO:0000250, ECO:0000269|PubMed:20208008}.
uniprot
proteins
mass_dalton
58407
uniprot
proteins
post_translational_modification
PTM: N-glycosylated. {ECO:0000269|PubMed:20208008}.
uniprot
proteins
protein_family
BTN/MOG family
uniprot
proteins
protein_family
Immunoglobulin superfamily
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
20208008
uniprot
proteins
pubmed
8541302
uniprot
proteins
pubmed
8995761
uniprot
proteins
sequence_length
524
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. Note=Secreted in association with the milk-fat-globule membrane during lactation.
uniprot
proteins
transmembrane_region
TRANSMEM 248..268; /note="Helical"; /evidence="ECO:0000255
uniprot
proteins