Sag
entrez
25539
canonical
uniprot
P15887
canonical
ensembl
ENSRNOG00000018185
resolver
ensembl
ENSRNOG00055008233
resolver
ensembl
ENSRNOG00060010282
resolver
ensembl
ENSRNOG00065020862
resolver
ensp
ENSRNOP00000071579
resolver
ensp
ENSRNOP00055011188
resolver
ensp
ENSRNOP00060013507
resolver
ensp
ENSRNOP00065028533
resolver
enst
ENSRNOT00000085770
resolver
enst
ENSRNOT00055013948
resolver
enst
ENSRNOT00060017383
resolver
enst
ENSRNOT00065035425
resolver
genesymbol
Sag
resolver
uniprot_entry
ARRS_RAT
resolver
amino_acid_sequence
MAACVKTNKSHVIFKKVSRDKSVTIYLGKRDYIDHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLYFSRVQVYPPVGAMSAPTQLQLSLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEVKAFATDITDAEEDKIPKKSSVRLLIRKVQHAPPEMGPQPCAEASWQFFMSDKPLHLSVSLSKEIYFHGEPIPVTVTVTNNTEKVVKKIKVSVEQIANVVLYSSDYYVKPVASEETQEKVQPNSTLTKTLVLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDRTVMGILVSYHIKVKLTVSGFLGELTSSEVATEVPFRLMHPQPEDPAKESVQDENLVFEEFARQNLKDTGENTEGKKDEDAGQDE
uniprot
proteins
function
FUNCTION: Involved in the regulation of phototransduction, playing a key role in signal termination after rhodopsin (RHO) has been activated by light in rod photoreceptors. Binds to photoactivated and phosphorylated RHO, preventing its interaction with transducin (GNAT1) and terminating transducin-mediated opsin signaling (By similarity). May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (By similarity). {ECO:0000250|UniProtKB:P08168, ECO:0000250|UniProtKB:P20443}.
uniprot
proteins
mass_dalton
44950
uniprot
proteins
protein_family
Arrestin family
uniprot
proteins
pubmed
16641100
uniprot
proteins
pubmed
2213004
uniprot
proteins
pubmed
2373176
uniprot
proteins
pubmed
2714438
uniprot
proteins
sequence_length
403
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Photoreceptor inner segment {ECO:0000250|UniProtKB:P20443}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P20443}. Membrane {ECO:0000250|UniProtKB:P20443}; Peripheral membrane protein {ECO:0000250|UniProtKB:P20443}. Note=In dark-adapted retina, it is predominatly localized to the outer nuclear layer and photoreceptor inner segments. Localized to photoreceptor outer segments in light-exposed retina. During light exposure it first accumulates in the proximal region of photoreceptor outer segments, and moves toward the distal tip of the outer segment as light exposure is prolonged. {ECO:0000250|UniProtKB:P20443}.
uniprot
proteins