Ier2
entrez
494344
canonical
uniprot
Q6P7D3
canonical
ensembl
ENSRNOG00000074928
resolver
ensp
ENSRNOP00000103117
resolver
ensp
ENSRNOP00000103402
resolver
ensp
ENSRNOP00000103930
resolver
enst
ENSRNOT00000143896
resolver
enst
ENSRNOT00000154538
resolver
enst
ENSRNOT00000166619
resolver
genesymbol
Ier2
resolver
uniprot_entry
IER2_RAT
resolver
amino_acid_sequence
MEVQKEAQRIMTLSVWKMYHSRMQRGGLRLHRSLQLSLVMRSARELYLSAKVETHQPEFPPSRRALDPRLHPPREPEAAMEAATPDVEQPPEPMDTQEEVLRVQETPALCDPPPARVSRKRRSSSDLSDGSDAGLVPSKKARLEEVEGEATSEVSNRLQLPPAQTEGAFPNLARVLQRRFSSLLNCGPAVPPPTPPTCEAKPACRPADNMLNVLVRTVVAF
uniprot
proteins
function
FUNCTION: DNA-binding protein that seems to act as a transcription factor (By similarity). Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (PubMed:17156131). May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity). Promotes cell motility, seems to stimulate tumor metastasis (By similarity). {ECO:0000250|UniProtKB:B7SXM5, ECO:0000250|UniProtKB:Q9BTL4, ECO:0000269|PubMed:17156131}.
uniprot
proteins
mass_dalton
24596
uniprot
proteins
protein_family
IER family
uniprot
proteins
pubmed
15489334
uniprot
proteins
pubmed
17156131
uniprot
proteins
sequence_length
221
uniprot
proteins
subcellular_location
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BTL4}. Nucleus {ECO:0000250|UniProtKB:Q9BTL4}. Note=Cytoplasmic during quiescence, translocates to the nucleus upon stimulation. {ECO:0000250|UniProtKB:Q9BTL4}.
uniprot
proteins